# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- PIF1 PF05970.9 KNZ71251.1 - 3.5e-16 59.1 0.1 3.8e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Toxin_51 PF15531.1 KNZ71252.1 - 0.09 12.5 1.2 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Putative toxin 51 Ycf1 PF05758.7 KNZ71252.1 - 1.6 6.3 1.5 2.2 5.8 1.0 1.1 1 0 0 1 1 1 0 Ycf1 ATP-grasp_2 PF08442.5 KNZ71253.1 - 6.4e-66 221.5 0.9 3.1e-65 219.3 0.2 2.0 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 KNZ71253.1 - 2.4e-26 92.1 0.2 4.6e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KNZ71253.1 - 8.4e-11 41.5 0.3 1.9e-10 40.3 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KNZ71253.1 - 0.00031 20.5 0.0 0.00055 19.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KNZ71253.1 - 0.00086 18.9 0.1 0.015 14.8 0.0 2.3 1 1 1 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.12 KNZ71253.1 - 0.0026 17.0 0.2 0.15 11.3 0.0 2.4 1 1 1 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PASTA PF03793.14 KNZ71253.1 - 0.03 13.9 0.3 3.5 7.3 0.0 2.8 2 0 0 2 2 2 0 PASTA domain ATP-grasp PF02222.17 KNZ71253.1 - 0.045 13.1 0.0 0.13 11.5 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain Succ_CoA_lig PF13607.1 KNZ71253.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain SGT1 PF07093.6 KNZ71254.1 - 3e-117 392.4 24.5 2.9e-106 356.1 0.0 3.0 2 1 1 3 3 3 3 SGT1 protein XPA_C PF05181.7 KNZ71255.1 - 1.9e-28 97.8 3.3 3.8e-28 96.8 2.3 1.6 1 0 0 1 1 1 1 XPA protein C-terminus APC_CDC26 PF10471.4 KNZ71255.1 - 8.8e-05 23.1 0.9 8.8e-05 23.1 0.6 3.3 3 1 0 3 3 3 1 Anaphase-promoting complex APC subunit 1 XPA_N PF01286.13 KNZ71255.1 - 0.079 12.6 9.3 0.047 13.3 2.6 2.4 2 0 0 2 2 2 0 XPA protein N-terminal PWWP PF00855.12 KNZ71255.1 - 1.4 9.1 5.5 0.18 11.9 0.4 2.2 3 0 0 3 3 3 0 PWWP domain Cobl PF09469.5 KNZ71255.1 - 1.6 8.7 0.0 1.6 8.7 0.0 3.3 3 1 0 3 3 3 0 Cordon-bleu ubiquitin-like domain Hist_deacetyl PF00850.14 KNZ71256.1 - 4.5e-80 269.2 0.0 5.9e-80 268.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain MFS_1 PF07690.11 KNZ71257.1 - 1.4e-19 70.0 37.5 3.6e-18 65.3 3.6 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Asparaginase_2 PF01112.13 KNZ71258.1 - 8.7e-54 182.3 0.0 1.4e-53 181.6 0.0 1.3 1 1 0 1 1 1 1 Asparaginase DGF-1_5 PF11038.3 KNZ71258.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 G_glu_transpept PF01019.16 KNZ71258.1 - 0.07 11.6 0.1 0.12 10.8 0.1 1.3 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase STE3 PF02076.10 KNZ71259.1 - 2.2e-54 184.4 16.5 2.9e-54 184.0 11.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor EBP PF05241.7 KNZ71260.1 - 8e-07 28.2 8.7 1.1e-06 27.8 6.0 1.1 1 0 0 1 1 1 1 Emopamil binding protein DUF1626 PF07788.6 KNZ71260.1 - 0.083 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1626) DUF3311 PF11755.3 KNZ71260.1 - 3.5 7.2 9.8 4.4 6.9 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) Pex24p PF06398.6 KNZ71262.1 - 2.7e-22 79.0 5.4 2.4e-18 66.0 0.0 2.5 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Kdo PF06293.9 KNZ71263.1 - 1.4e-05 24.2 0.1 2e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KNZ71263.1 - 1.6e-05 24.3 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KNZ71263.1 - 4.9e-05 23.1 1.5 0.0041 16.8 0.7 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ71263.1 - 0.00088 18.5 0.2 0.0013 17.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.6 KNZ71263.1 - 0.07 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.15 KNZ71263.1 - 0.099 12.2 2.3 1 8.9 1.6 2.3 1 1 0 1 1 1 0 Choline/ethanolamine kinase SH3_2 PF07653.12 KNZ71264.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.5 1 1 0 1 1 1 0 Variant SH3 domain zf-CCHC PF00098.18 KNZ71265.1 - 4e-06 26.4 2.9 4e-06 26.4 2.0 2.0 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.12 KNZ71265.1 - 0.00099 19.1 0.1 0.0029 17.6 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein SMN PF06003.7 KNZ71265.1 - 0.034 13.2 0.6 0.051 12.6 0.4 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) 7tm_1 PF00001.16 KNZ71266.1 - 0.0033 16.5 1.6 0.0056 15.8 1.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF788 PF05620.6 KNZ71266.1 - 0.13 12.1 0.2 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF788) MscS_TM PF12794.2 KNZ71266.1 - 0.16 10.5 3.1 0.27 9.7 2.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Ycf4 PF02392.11 KNZ71266.1 - 7.7 5.7 7.6 1.6 7.9 0.6 2.2 1 1 1 2 2 2 0 Ycf4 DUF2413 PF10310.4 KNZ71267.1 - 1e-69 235.5 0.5 2.6e-69 234.1 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) Complex1_30kDa PF00329.14 KNZ71268.1 - 2.1e-34 117.8 0.0 3.4e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BCAS2 PF05700.6 KNZ71269.1 - 2.4e-63 213.5 3.9 3.1e-63 213.1 2.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF2854 PF11016.3 KNZ71269.1 - 0.088 12.3 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) Imm29 PF15575.1 KNZ71269.1 - 0.1 12.1 1.5 0.22 11.1 0.1 1.9 2 0 0 2 2 2 0 Immunity protein 29 DUF2317 PF10079.4 KNZ71269.1 - 0.12 10.9 4.1 0.23 10.0 2.8 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Nup54 PF13874.1 KNZ71269.1 - 0.19 11.3 7.4 1.1 8.9 0.7 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF4404 PF14357.1 KNZ71269.1 - 0.2 12.1 2.8 2.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Baculo_PEP_C PF04513.7 KNZ71269.1 - 0.4 10.5 4.7 0.87 9.4 3.3 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC155 PF14662.1 KNZ71269.1 - 1.9 8.0 12.2 0.63 9.6 6.3 1.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 APG6 PF04111.7 KNZ71269.1 - 5 6.0 11.0 0.23 10.4 3.9 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF1843 PF08898.5 KNZ71269.1 - 10 6.2 12.3 12 5.9 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Cut8_N PF14482.1 KNZ71270.1 - 2.6 8.0 10.6 1.3 9.0 0.1 3.2 3 0 0 3 3 3 0 Cut8 proteasome-binding domain COesterase PF00135.23 KNZ71271.1 - 4.4e-85 286.4 0.2 3.7e-74 250.3 0.1 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ71271.1 - 8.5e-11 41.8 0.2 1.2e-09 38.0 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ71271.1 - 5.6e-05 22.9 0.0 0.00017 21.4 0.0 1.8 1 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ71271.1 - 0.047 12.9 0.0 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KNZ71271.1 - 0.064 13.1 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family MARVEL PF01284.18 KNZ71274.1 - 0.13 12.1 11.7 0.43 10.3 7.8 2.0 1 1 0 1 1 1 0 Membrane-associating domain MFS_1 PF07690.11 KNZ71275.1 - 1.7e-14 53.3 17.0 2.2e-14 52.9 11.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ71275.1 - 0.043 12.4 12.2 0.7 8.3 8.5 2.6 1 1 0 1 1 1 0 Sugar (and other) transporter Trp_halogenase PF04820.9 KNZ71276.1 - 3.8e-24 85.1 0.0 8.1e-18 64.2 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase DAO PF01266.19 KNZ71276.1 - 0.029 13.2 0.0 0.15 10.9 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Cpl-7 PF08230.6 KNZ71276.1 - 1.2 8.8 3.0 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Cpl-7 lysozyme C-terminal domain ketoacyl-synt PF00109.21 KNZ71278.1 - 8.4e-07 28.7 0.1 1.2e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain TSC22 PF01166.13 KNZ71279.1 - 0.56 10.2 2.0 0.67 9.9 0.4 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family Coa1 PF08695.5 KNZ71280.1 - 1.6e-32 111.4 0.1 2.4e-32 110.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Abhydrolase_6 PF12697.2 KNZ71281.1 - 2.6e-23 83.0 0.0 3.3e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ71281.1 - 4.1e-11 42.8 0.1 4.5e-10 39.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ71281.1 - 3.5e-09 36.5 0.0 7.6e-09 35.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KNZ71281.1 - 1.7e-05 25.1 0.0 2.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 KNZ71281.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S15 PF02129.13 KNZ71281.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3328 PF11807.3 KNZ71282.1 - 1.2e-15 57.7 0.0 1.3e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_C2 PF00648.16 KNZ71286.1 - 8.9e-63 212.0 0.2 6.9e-41 140.1 0.1 2.1 2 0 0 2 2 2 2 Calpain family cysteine protease PEP_mutase PF13714.1 KNZ71287.1 - 7.1e-43 146.5 3.1 9.5e-43 146.1 2.2 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KNZ71287.1 - 3e-20 71.9 0.7 4e-20 71.5 0.5 1.3 1 0 0 1 1 1 1 Isocitrate lyase family GMC_oxred_N PF00732.14 KNZ71288.1 - 5.1e-50 170.2 0.0 6.6e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ71288.1 - 1.5e-38 132.3 0.0 2.4e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KNZ71288.1 - 0.0014 17.6 0.0 0.012 14.5 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KNZ71288.1 - 0.0014 18.5 0.1 0.0037 17.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KNZ71288.1 - 0.002 17.1 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KNZ71288.1 - 0.028 13.2 0.3 0.31 9.8 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 KNZ71288.1 - 0.039 13.8 0.0 0.54 10.1 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Jiraiya PF15038.1 KNZ71289.1 - 0.13 11.6 3.7 0.25 10.7 2.6 1.4 1 0 0 1 1 1 0 Jiraiya NB-ARC PF00931.17 KNZ71290.1 - 0.053 12.3 0.0 0.061 12.1 0.0 1.0 1 0 0 1 1 1 0 NB-ARC domain HNH_2 PF13391.1 KNZ71292.1 - 0.0012 18.5 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease HsbA PF12296.3 KNZ71293.1 - 1.1e-07 31.6 2.7 2e-07 30.9 1.9 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A LAGLIDADG_1 PF00961.14 KNZ71294.1 - 1.1e-25 90.1 0.0 1.2e-14 54.6 0.0 2.4 2 0 0 2 2 2 2 LAGLIDADG endonuclease COX1 PF00115.15 KNZ71294.1 - 5e-19 68.2 1.8 9.1e-19 67.4 1.2 1.3 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I LAGLIDADG_3 PF14528.1 KNZ71294.1 - 2.2e-06 27.8 0.0 0.0039 17.4 0.0 2.6 2 0 0 2 2 2 2 LAGLIDADG-like domain Endonuc_subdom PF09062.5 KNZ71294.1 - 0.0015 19.2 0.0 0.07 13.8 0.0 2.8 2 0 0 2 2 2 1 PI-PfuI Endonuclease subdomain Hom_end PF05204.9 KNZ71294.1 - 0.11 12.4 0.0 20 5.1 0.0 2.7 2 1 0 2 2 2 0 Homing endonuclease ATP-synt_C PF00137.16 KNZ71295.1 - 4.3e-17 61.7 11.4 5.5e-17 61.4 7.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit C NfeD PF01957.13 KNZ71295.1 - 0.027 14.5 0.8 0.033 14.3 0.6 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF1469 PF07332.6 KNZ71295.1 - 1.1 8.9 7.0 1.2 8.8 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) COX1 PF00115.15 KNZ71296.1 - 1e-17 63.9 3.6 1.6e-17 63.2 2.5 1.3 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I NUMOD3 PF07460.6 KNZ71296.1 - 1.1e-05 25.2 1.1 0.19 11.6 0.0 3.5 3 1 1 4 4 4 2 NUMOD3 motif (2 copies) GIY-YIG PF01541.19 KNZ71296.1 - 0.00012 22.3 0.1 0.00024 21.3 0.1 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain NUMOD1 PF07453.8 KNZ71296.1 - 0.07 13.0 0.1 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 NUMOD1 domain Tropomyosin_1 PF12718.2 KNZ71297.1 - 1.6e-14 53.9 21.9 4.2e-10 39.6 9.5 2.1 2 0 0 2 2 2 2 Tropomyosin like ROF PF07073.7 KNZ71297.1 - 0.0039 17.1 3.2 0.26 11.3 0.2 2.5 1 1 0 2 2 2 2 Modulator of Rho-dependent transcription termination (ROF) End3 PF12761.2 KNZ71297.1 - 0.094 12.3 13.0 2.5 7.6 1.1 2.4 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Cep57_MT_bd PF06657.8 KNZ71297.1 - 0.59 10.1 11.0 3.7 7.5 0.9 3.2 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF1319 PF07028.6 KNZ71297.1 - 2.7 8.1 13.3 13 6.0 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) CHD5 PF04420.9 KNZ71297.1 - 3.6 7.2 7.7 3.8 7.1 0.6 3.1 1 1 2 3 3 3 0 CHD5-like protein Phage_GP20 PF06810.6 KNZ71297.1 - 4.1 6.8 18.6 0.6 9.5 7.5 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 Atg14 PF10186.4 KNZ71297.1 - 4.4 6.1 15.1 0.28 10.0 6.1 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Cob_adeno_trans PF01923.13 KNZ71297.1 - 7 6.4 8.8 5.4 6.7 2.8 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Occludin_ELL PF07303.8 KNZ71297.1 - 8 7.2 8.9 14 6.4 4.0 2.5 1 1 0 2 2 2 0 Occludin homology domain OmpH PF03938.9 KNZ71297.1 - 9.7 6.1 20.8 0.74 9.7 10.0 1.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF3334 PF11813.3 KNZ71298.1 - 0.15 11.6 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) Ribosomal_L37e PF01907.14 KNZ71300.1 - 9.7e-25 86.1 12.3 1.7e-24 85.3 8.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 KNZ71300.1 - 0.00037 20.2 2.5 0.00057 19.6 1.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 KNZ71300.1 - 0.013 15.1 0.4 0.019 14.6 0.3 1.5 1 1 0 1 1 1 0 SelR domain LIM PF00412.17 KNZ71300.1 - 0.024 14.6 2.3 0.035 14.1 1.6 1.3 1 0 0 1 1 1 0 LIM domain C1_1 PF00130.17 KNZ71300.1 - 0.036 13.7 4.1 0.058 13.1 2.8 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.14 KNZ71300.1 - 0.036 13.7 0.8 0.054 13.1 0.6 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 KNZ71300.1 - 0.13 11.5 3.5 0.34 10.1 2.5 1.6 1 1 1 2 2 2 0 zinc-ribbon domain zf-RING_5 PF14634.1 KNZ71300.1 - 0.18 11.5 5.1 0.28 10.9 3.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_2 PF13240.1 KNZ71300.1 - 0.46 10.0 5.3 3.2 7.3 3.8 2.0 1 1 1 2 2 2 0 zinc-ribbon domain GFA PF04828.9 KNZ71300.1 - 0.57 10.1 4.6 5.3 7.0 2.9 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4_2 PF13923.1 KNZ71300.1 - 2.1 8.4 5.9 3.4 7.7 4.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ISL3 PF14690.1 KNZ71300.1 - 2.2 8.3 7.6 1.1 9.2 0.6 3.0 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 YhfH PF14149.1 KNZ71300.1 - 3.3 7.5 5.3 4.2 7.2 1.0 2.2 1 1 1 2 2 2 0 YhfH-like protein zf-C3HC4 PF00097.20 KNZ71300.1 - 3.9 7.1 6.5 6.8 6.4 4.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.16 KNZ71300.1 - 5.5 6.4 9.3 6.4 6.2 0.2 2.7 1 1 2 3 3 3 0 Ribosomal protein S14p/S29e Aminotran_3 PF00202.16 KNZ71301.1 - 7.5e-06 25.0 0.0 1.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III adh_short_C2 PF13561.1 KNZ71302.1 - 2.3e-28 99.5 0.0 3e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KNZ71302.1 - 2.5e-19 69.8 0.5 3.6e-19 69.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ71302.1 - 7.7e-10 38.7 0.1 1.1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KNZ71302.1 - 0.0057 15.6 0.0 0.0092 14.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase His_biosynth PF00977.16 KNZ71302.1 - 0.015 14.5 0.1 0.036 13.3 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein Flavodoxin_4 PF12682.2 KNZ71302.1 - 0.1 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin PA PF02225.17 KNZ71302.1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 PA domain LAGLIDADG_2 PF03161.8 KNZ71303.1 - 2.7e-33 115.3 0.6 8.5e-33 113.7 0.4 1.7 1 1 0 1 1 1 1 LAGLIDADG DNA endonuclease family Alpha_kinase PF02816.13 KNZ71303.1 - 0.075 12.6 1.6 0.14 11.7 1.1 1.6 1 1 0 1 1 1 0 Alpha-kinase family SUI1 PF01253.17 KNZ71303.1 - 0.1 12.4 0.1 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor SUI1 Cytochrom_B_C PF00032.12 KNZ71304.1 - 9.8e-18 64.2 2.2 1.4e-17 63.7 1.5 1.2 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD CbiQ PF02361.11 KNZ71304.1 - 0.046 13.2 2.8 0.06 12.9 1.9 1.3 1 1 0 1 1 1 0 Cobalt transport protein LAGLIDADG_2 PF03161.8 KNZ71305.1 - 5.5e-40 137.1 1.4 6.8e-40 136.8 0.9 1.1 1 0 0 1 1 1 1 LAGLIDADG DNA endonuclease family LAGLIDADG_3 PF14528.1 KNZ71305.1 - 0.11 12.6 1.1 0.81 9.9 0.1 2.4 2 1 0 2 2 2 0 LAGLIDADG-like domain ABC2_membrane PF01061.19 KNZ71307.1 - 2.5e-28 98.6 16.9 6.8e-28 97.2 11.7 1.8 1 1 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.7 KNZ71307.1 - 1.9e-06 27.4 0.3 4.4e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 CDR ABC transporter TPP_enzyme_M PF00205.17 KNZ71308.1 - 2.3e-21 75.9 0.0 3.7e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KNZ71308.1 - 1e-11 44.6 0.0 3.7e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 KNZ71308.1 - 2.9e-06 26.8 0.0 4.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain zf-CCHC PF00098.18 KNZ71311.1 - 0.62 10.0 5.0 1.2 9.1 3.5 1.5 1 0 0 1 1 1 0 Zinc knuckle p450 PF00067.17 KNZ71312.1 - 1.6e-43 148.8 0.0 2e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Adaptin_N PF01602.15 KNZ71313.1 - 4.5e-55 186.9 0.7 5.7e-55 186.6 0.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KNZ71313.1 - 0.00017 21.7 0.0 0.031 14.5 0.0 2.8 1 1 2 3 3 3 2 HEAT repeats Arm PF00514.18 KNZ71313.1 - 0.57 10.1 2.2 28 4.7 0.1 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Fungal_trans PF04082.13 KNZ71314.1 - 4.8e-06 25.6 0.0 7.6e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Asp_protease_2 PF13650.1 KNZ71315.1 - 1.4e-07 31.8 0.0 3e-07 30.8 0.0 1.5 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.5 KNZ71315.1 - 0.0038 16.7 0.1 0.0059 16.1 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KNZ71315.1 - 0.0039 16.9 0.0 0.0078 16.0 0.0 1.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Phage_int_SAM_1 PF02899.12 KNZ71316.1 - 0.063 13.4 0.4 0.69 10.0 0.0 2.5 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF760 PF05542.6 KNZ71317.1 - 0.18 11.9 1.3 0.67 10.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF760) GvpH PF05455.6 KNZ71318.1 - 0.013 15.1 0.1 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 GvpH Glyco_hydro_43 PF04616.9 KNZ71319.1 - 3.1e-05 23.2 0.0 3.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_61 PF03443.9 KNZ71321.1 - 5e-09 36.2 0.0 5.4e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Asp_protease_2 PF13650.1 KNZ71322.1 - 4.9e-07 30.1 0.0 3.4e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.5 KNZ71322.1 - 0.0064 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Pkinase PF00069.20 KNZ71324.1 - 0.0011 18.1 0.0 0.0011 18.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ71324.1 - 0.029 13.4 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase XH PF03469.9 KNZ71324.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 XH domain Cytochrom_B_N_2 PF13631.1 KNZ71325.1 - 5e-53 179.3 16.9 6e-53 179.0 11.7 1.1 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_N PF00033.14 KNZ71325.1 - 2.5e-15 56.3 12.4 2.5e-15 56.3 8.6 1.5 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.12 KNZ71325.1 - 0.14 12.4 0.7 0.14 12.4 0.5 3.7 2 1 2 4 4 4 0 Cytochrome b(C-terminal)/b6/petD OppC_N PF12911.2 KNZ71325.1 - 4.1 6.8 13.7 0.19 11.1 1.9 2.9 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C PIF1 PF05970.9 KNZ71326.1 - 3.7e-23 82.0 0.1 4.2e-23 81.8 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase PAE PF03283.8 KNZ71326.1 - 0.0085 14.7 0.1 0.0085 14.7 0.1 1.1 1 0 0 1 1 1 1 Pectinacetylesterase p450 PF00067.17 KNZ71327.1 - 2.2e-22 79.2 0.0 2.6e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BNIP2 PF12496.3 KNZ71330.1 - 0.056 13.6 1.7 0.075 13.1 1.2 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Oxidored_q2 PF00420.19 KNZ71331.1 - 1.1e-19 69.7 13.0 1.2e-19 69.6 9.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Claudin_2 PF13903.1 KNZ71331.1 - 1.1 8.9 6.7 0.47 10.1 3.1 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Gram_pos_anchor PF00746.16 KNZ71331.1 - 5.8 6.8 11.4 7.5 6.4 0.0 2.9 2 1 1 3 3 3 0 Gram positive anchor Herpes_LMP1 PF05297.6 KNZ71331.1 - 7.6 5.3 10.7 8 5.2 7.4 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF843 PF05814.6 KNZ71331.1 - 7.9 6.3 9.6 11 5.9 6.7 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) Macoilin PF09726.4 KNZ71332.1 - 0.69 8.1 4.7 0.84 7.8 3.3 1.0 1 0 0 1 1 1 0 Transmembrane protein KAR9 PF08580.5 KNZ71332.1 - 1 7.5 6.2 1.1 7.4 4.3 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 ORC6 PF05460.8 KNZ71332.1 - 1.1 8.3 5.8 1.4 7.9 4.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SR-25 PF10500.4 KNZ71332.1 - 1.2 8.5 9.5 2.1 7.7 6.6 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF566 PF04484.7 KNZ71332.1 - 3.7 6.9 11.1 5.1 6.5 7.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) ketoacyl-synt PF00109.21 KNZ71333.1 - 4.3e-34 118.1 1.8 7.7e-33 114.0 0.5 2.0 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KNZ71333.1 - 2.3e-31 108.1 0.4 3.2e-31 107.6 0.3 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KNZ71333.1 - 0.00011 21.3 0.2 0.001 18.0 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain zf-CCHC_5 PF14787.1 KNZ71334.1 - 3.8 7.0 12.0 0.37 10.3 2.3 2.6 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger PolC_DP2 PF03833.8 KNZ71334.1 - 5.6 4.4 5.8 7.3 4.1 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 GDA1_CD39 PF01150.12 KNZ71335.1 - 4.9e-30 104.3 0.0 2e-29 102.3 0.0 1.7 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 KNZ71335.1 - 0.082 12.0 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Ppx/GppA phosphatase family RVP_2 PF08284.6 KNZ71336.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease LBR_tudor PF09465.5 KNZ71337.1 - 0.085 12.4 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain BAR_2 PF10455.4 KNZ71338.1 - 1.7e-10 40.3 1.0 2.1e-10 39.9 0.7 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking MUG2_C PF08593.5 KNZ71338.1 - 0.099 12.8 0.6 0.21 11.8 0.3 1.8 1 1 0 1 1 1 0 Meiotically up-regulated glycoproteins C-terminal DUF3328 PF11807.3 KNZ71339.1 - 1.1e-18 67.7 0.0 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PIF1 PF05970.9 KNZ71340.1 - 2.8e-28 98.9 0.0 3.1e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase COX2_TM PF02790.10 KNZ71341.1 - 7.6e-28 96.3 1.5 8.8e-28 96.1 1.0 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain GpcrRhopsn4 PF10192.4 KNZ71341.1 - 0.038 13.1 4.7 0.042 13.0 3.2 1.0 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain zf-DHHC PF01529.15 KNZ71341.1 - 1.5 8.1 4.3 1.8 7.9 3.0 1.0 1 0 0 1 1 1 0 DHHC palmitoyltransferase COX2 PF00116.15 KNZ71342.1 - 2.1e-24 85.6 0.0 2.4e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Herpes_Helicase PF02689.9 KNZ71344.1 - 0.0001 20.2 0.0 0.0001 20.2 0.0 1.0 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 KNZ71345.1 - 6.2e-22 78.0 0.0 7.5e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 KNZ71345.1 - 0.018 14.9 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2576 PF10845.3 KNZ71345.1 - 0.16 11.1 0.2 0.37 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) Pkinase PF00069.20 KNZ71348.1 - 0.00016 20.9 0.0 0.00016 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KNZ71348.1 - 0.00018 20.6 0.0 0.00022 20.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ71348.1 - 0.0004 20.1 0.5 0.0005 19.8 0.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KNZ71348.1 - 0.015 14.2 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 KNZ71348.1 - 0.059 12.9 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 KNZ71348.1 - 0.13 11.2 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Chromo PF00385.19 KNZ71349.1 - 1.1e-16 60.1 0.3 1.5e-16 59.7 0.2 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SF3a60_bindingd PF12108.3 KNZ71349.1 - 0.0077 15.7 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain Mtf2_C PF14061.1 KNZ71349.1 - 0.11 12.3 0.9 0.16 11.8 0.6 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 ATP-synt_A PF00119.15 KNZ71350.1 - 1.6e-25 89.8 11.2 1.8e-25 89.7 7.7 1.0 1 0 0 1 1 1 1 ATP synthase A chain DUF1290 PF06947.7 KNZ71350.1 - 0.17 11.8 8.3 2.1 8.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1290) Herpes_LMP1 PF05297.6 KNZ71350.1 - 1.2 7.9 7.7 1.4 7.7 5.3 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) BofA PF07441.6 KNZ71350.1 - 2.1 8.3 11.6 3.4 7.7 2.9 2.1 1 1 1 2 2 2 0 SigmaK-factor processing regulatory protein BofA Chromo PF00385.19 KNZ71351.1 - 1.2e-16 60.1 0.2 1.5e-16 59.8 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KNZ71351.1 - 0.066 13.1 0.2 0.09 12.6 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 COX3 PF00510.13 KNZ71354.1 - 4.5e-25 88.5 10.9 4.9e-25 88.4 7.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III PepSY_TM_2 PF13703.1 KNZ71354.1 - 0.19 11.8 3.9 0.24 11.6 2.7 1.2 1 0 0 1 1 1 0 PepSY-associated TM helix DUF308 PF03729.8 KNZ71354.1 - 1.3 9.0 6.8 7.1 6.6 4.7 1.9 1 1 0 1 1 1 0 Short repeat of unknown function (DUF308) DUF3955 PF13127.1 KNZ71354.1 - 2.4 7.7 5.9 1.9 8.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3955) FixQ PF05545.6 KNZ71354.1 - 8.1 6.1 8.2 9.6 5.9 0.1 2.2 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ NTP_transferase PF00483.18 KNZ71355.1 - 4.9e-31 107.9 0.0 1.4e-30 106.3 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyl transferase MannoseP_isomer PF01050.13 KNZ71355.1 - 0.0002 20.9 0.1 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase NTP_transf_3 PF12804.2 KNZ71355.1 - 0.00058 19.9 0.2 0.0015 18.6 0.2 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain YejG PF13989.1 KNZ71355.1 - 0.061 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 YejG-like protein DUF364 PF04016.7 KNZ71355.1 - 0.078 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF364) DivIC PF04977.10 KNZ71355.1 - 0.86 9.1 3.0 0.38 10.2 0.4 1.6 2 0 0 2 2 2 0 Septum formation initiator DUF4610 PF15384.1 KNZ71356.1 - 0.09 12.2 0.3 0.14 11.7 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4610) G-alpha PF00503.15 KNZ71357.1 - 6.2e-108 360.9 0.5 3.1e-65 220.3 0.0 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 KNZ71357.1 - 3.2e-08 33.0 1.0 0.025 13.8 0.4 3.4 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 KNZ71357.1 - 0.011 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KNZ71357.1 - 0.015 15.4 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mrr_cat_2 PF13156.1 KNZ71358.1 - 0.012 15.4 1.6 0.017 15.0 1.0 1.4 1 1 0 1 1 1 0 Restriction endonuclease DUF1643 PF07799.7 KNZ71358.1 - 0.26 10.9 1.6 0.31 10.7 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1643) DUF883 PF05957.8 KNZ71358.1 - 1.9 8.9 16.8 11 6.5 5.3 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) HisKA_3 PF07730.8 KNZ71358.1 - 2.8 8.3 5.0 2.8 8.3 0.1 3.0 2 1 2 4 4 4 0 Histidine kinase AAA_18 PF13238.1 KNZ71359.1 - 2.7e-10 40.6 2.7 2e-09 37.8 1.9 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ71359.1 - 1e-07 32.8 0.5 5.2e-07 30.4 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KNZ71359.1 - 5.5e-06 26.3 0.0 1.5e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KNZ71359.1 - 0.017 14.2 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.13 KNZ71359.1 - 0.033 13.7 0.1 0.18 11.3 0.1 1.9 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family T2SE PF00437.15 KNZ71359.1 - 0.073 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.1 KNZ71359.1 - 0.083 12.8 0.8 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 KNZ71359.1 - 0.12 11.6 0.1 0.26 10.4 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 FAD_binding_2 PF00890.19 KNZ71360.1 - 1.8e-75 254.3 1.6 6.1e-66 222.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Cyt-b5 PF00173.23 KNZ71360.1 - 5.5e-23 80.5 0.0 1.3e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_2 PF07992.9 KNZ71360.1 - 2.1e-10 40.8 0.0 3.2e-05 23.9 0.0 3.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KNZ71360.1 - 4.1e-10 39.0 1.1 8.7e-07 28.1 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 KNZ71360.1 - 5.3e-07 28.8 0.2 7.9e-05 21.6 0.0 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KNZ71360.1 - 4.7e-06 26.5 0.3 4.7e-06 26.5 0.2 3.3 4 1 0 4 4 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KNZ71360.1 - 6.4e-06 25.4 0.4 1.1e-05 24.6 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KNZ71360.1 - 3.5e-05 23.0 0.4 0.039 13.0 0.1 2.5 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 KNZ71360.1 - 5.4e-05 21.8 4.6 0.00013 20.5 0.3 2.8 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.1 KNZ71360.1 - 6.7e-05 23.0 0.2 0.00017 21.6 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNZ71360.1 - 0.00027 20.7 0.1 0.68 9.6 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KNZ71360.1 - 0.0014 17.7 1.5 0.0028 16.8 0.6 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KNZ71360.1 - 0.0032 16.4 0.5 0.017 14.0 0.3 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 KNZ71360.1 - 0.0036 17.6 0.2 0.038 14.3 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KNZ71360.1 - 0.015 15.5 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 KNZ71360.1 - 0.084 12.4 0.4 0.14 11.6 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 KNZ71360.1 - 0.12 11.4 1.3 0.22 10.5 0.4 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 KNZ71360.1 - 0.19 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M19 PF01244.16 KNZ71361.1 - 2.9e-100 335.3 0.0 3.6e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) G-patch_2 PF12656.2 KNZ71362.1 - 4.6e-26 90.4 0.0 3.6e-25 87.6 0.0 2.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site G-patch PF01585.18 KNZ71362.1 - 0.0078 15.9 0.9 0.03 14.1 0.6 2.1 1 1 0 1 1 1 1 G-patch domain Pantoate_transf PF02548.10 KNZ71363.1 - 6.3e-67 225.4 0.1 7e-46 156.4 0.0 3.2 2 1 1 3 3 3 3 Ketopantoate hydroxymethyltransferase Ras PF00071.17 KNZ71363.1 - 5.1e-35 120.2 0.0 8.4e-35 119.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ71363.1 - 4.1e-09 36.9 0.0 9e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Chs3p PF12271.3 KNZ71364.1 - 4.8e-15 55.2 0.5 5.5e-15 55.1 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF4239 PF14023.1 KNZ71364.1 - 0.17 11.2 1.6 0.22 10.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Atg14 PF10186.4 KNZ71369.1 - 1.3e-49 168.8 0.0 1.7e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 EzrA PF06160.7 KNZ71369.1 - 0.0029 15.8 1.0 0.0043 15.3 0.7 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA APG6 PF04111.7 KNZ71369.1 - 0.026 13.5 0.6 0.21 10.5 0.3 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4094 PF13334.1 KNZ71369.1 - 0.085 13.2 0.6 0.38 11.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) zf-B_box PF00643.19 KNZ71369.1 - 0.19 11.6 4.6 0.35 10.7 3.2 1.4 1 0 0 1 1 1 0 B-box zinc finger Aldedh PF00171.17 KNZ71370.1 - 8.8e-171 568.2 0.0 1e-170 568.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KNZ71370.1 - 0.03 13.0 0.0 0.078 11.6 0.0 1.6 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Pkinase PF00069.20 KNZ71371.1 - 1.9e-14 53.4 0.0 4.3e-09 35.8 0.0 3.0 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ71371.1 - 1.5e-13 50.4 0.2 1.1e-06 27.8 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Peptidase_M36 PF02128.10 KNZ71373.1 - 1.8e-107 359.4 3.0 2.3e-107 359.1 2.1 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.10 KNZ71373.1 - 0.00076 19.2 0.0 0.0021 17.7 0.0 1.7 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain PepSY PF03413.14 KNZ71373.1 - 0.03 14.9 0.1 0.083 13.5 0.0 1.8 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Peptidase_MA_2 PF13485.1 KNZ71373.1 - 0.039 13.9 0.1 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase MA superfamily Chromo PF00385.19 KNZ71376.1 - 8.3e-10 38.1 0.5 1.2e-09 37.6 0.3 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KNZ71376.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Tannase PF07519.6 KNZ71379.1 - 1e-78 265.1 0.0 1.3e-78 264.8 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase PIF1 PF05970.9 KNZ71381.1 - 5.3e-34 117.7 0.1 6.6e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 KNZ71381.1 - 2.4e-05 22.3 0.0 2.9e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Helicase UPF0160 PF03690.8 KNZ71382.1 - 2.5e-122 408.2 0.0 3.3e-122 407.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) SAD_SRA PF02182.12 KNZ71384.1 - 5.8e-29 100.4 0.0 5.9e-28 97.1 0.0 2.0 1 1 0 1 1 1 1 SAD/SRA domain SNARE PF05739.14 KNZ71385.1 - 2.6e-07 30.2 3.3 2.6e-07 30.2 2.3 3.0 4 1 0 4 4 4 1 SNARE domain DUF4398 PF14346.1 KNZ71385.1 - 0.74 9.9 15.0 0.038 14.0 6.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Mpp10 PF04006.7 KNZ71386.1 - 1.7e-95 320.6 49.6 4e-95 319.4 34.4 1.4 1 1 0 1 1 1 1 Mpp10 protein Fig1 PF12351.3 KNZ71387.1 - 0.82 9.5 16.9 0.15 11.9 5.8 2.5 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Lyase_8 PF02278.13 KNZ71388.1 - 2.8e-27 95.7 0.9 4.9e-27 94.9 0.6 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 KNZ71388.1 - 4e-15 55.5 2.1 1.8e-11 43.5 0.2 2.2 2 0 0 2 2 2 2 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8 PF02278.13 KNZ71390.1 - 5.3e-36 124.3 1.8 8.5e-36 123.7 1.2 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 KNZ71390.1 - 6.2e-12 45.0 0.0 1.1e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.12 KNZ71390.1 - 0.00089 19.2 0.0 0.0026 17.7 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Thiolase_N PF00108.18 KNZ71391.1 - 9e-70 234.6 0.0 1.6e-69 233.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KNZ71391.1 - 6e-36 122.5 0.1 1.4e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain Ribosomal_S3_C PF00189.15 KNZ71391.1 - 1.1e-16 60.7 0.0 3.2e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KNZ71391.1 - 8.4e-12 44.4 0.0 1.7e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 KH domain ACP_syn_III PF08545.5 KNZ71391.1 - 0.0034 17.0 0.6 0.45 10.2 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KNZ71391.1 - 0.0058 16.1 0.5 0.0058 16.1 0.4 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain UN_NPL4 PF11543.3 KNZ71391.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Ldh_1_C PF02866.13 KNZ71391.1 - 0.12 12.0 0.0 3.7 7.2 0.0 2.8 2 1 1 3 3 3 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ribosomal_L32p PF01783.18 KNZ71392.1 - 3.5e-09 36.6 1.8 4.6e-09 36.3 1.3 1.2 1 1 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.1 KNZ71392.1 - 0.015 15.0 2.3 0.028 14.1 1.6 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-UBR PF02207.15 KNZ71392.1 - 0.021 14.5 0.3 0.022 14.4 0.2 1.2 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Zn-ribbon_8 PF09723.5 KNZ71392.1 - 0.061 13.2 1.0 0.35 10.8 0.1 2.0 1 1 1 2 2 2 0 Zinc ribbon domain zf-C3HC4 PF00097.20 KNZ71392.1 - 0.12 12.0 2.3 6 6.6 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 KNZ71392.1 - 0.14 12.0 2.7 0.18 11.6 1.8 1.3 1 1 0 1 1 1 0 Double zinc ribbon zf-C4 PF00105.13 KNZ71392.1 - 0.17 12.1 1.3 0.37 11.0 0.7 1.7 1 1 1 2 2 2 0 Zinc finger, C4 type (two domains) Auto_anti-p27 PF06677.7 KNZ71392.1 - 0.59 9.9 4.3 1.2 9.0 0.2 2.1 1 1 1 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ribbon_3 PF13248.1 KNZ71392.1 - 1.2 8.3 5.3 2.6 7.3 3.7 1.6 1 1 0 1 1 1 0 zinc-ribbon domain ETC_C1_NDUFA5 PF04716.9 KNZ71393.1 - 8.3e-18 63.6 0.0 1.4e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region LSM PF01423.17 KNZ71394.1 - 4.7e-17 61.3 0.2 6.7e-17 60.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain PHD PF00628.24 KNZ71395.1 - 1.1e-10 41.0 7.8 1.1e-10 41.0 5.4 2.4 2 0 0 2 2 2 1 PHD-finger HABP4_PAI-RBP1 PF04774.10 KNZ71396.1 - 6.2e-05 23.4 11.0 6.2e-05 23.4 7.6 3.4 3 1 0 3 3 3 1 Hyaluronan / mRNA binding family His_Phos_1 PF00300.17 KNZ71397.1 - 4.8e-23 81.9 0.0 6.5e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KNZ71397.1 - 0.037 13.3 0.0 0.075 12.3 0.0 1.4 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Memo PF01875.12 KNZ71398.1 - 1e-68 231.2 0.0 2.6e-68 229.9 0.0 1.6 1 1 0 1 1 1 1 Memo-like protein Ribosomal_L32e PF01655.13 KNZ71398.1 - 6e-47 158.2 2.3 9.1e-47 157.6 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L32 WD40 PF00400.27 KNZ71399.1 - 9.1e-09 34.8 0.2 5e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 WD domain, G-beta repeat Pkinase PF00069.20 KNZ71400.1 - 2e-43 148.4 0.0 2.4e-42 144.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ71400.1 - 1.2e-16 60.6 0.0 1.1e-15 57.4 0.0 2.4 2 2 1 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ71400.1 - 0.00019 20.4 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ71400.1 - 0.00046 19.9 0.0 0.0012 18.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KNZ71400.1 - 0.011 14.7 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GTP_EFTU PF00009.22 KNZ71401.1 - 2.2e-56 190.2 0.1 3.5e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KNZ71401.1 - 7.8e-37 125.4 0.0 2.6e-36 123.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KNZ71401.1 - 1.4e-16 60.3 1.0 1.4e-16 60.3 0.7 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KNZ71401.1 - 8.3e-05 22.1 0.3 0.00024 20.6 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KNZ71401.1 - 0.0013 18.6 0.4 0.0042 17.0 0.3 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.13 KNZ71401.1 - 0.041 13.7 0.1 0.42 10.4 0.0 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain SKG6 PF08693.5 KNZ71402.1 - 0.016 14.5 4.7 0.032 13.5 3.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 KNZ71402.1 - 0.11 12.9 0.9 0.27 11.6 0.6 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 KNZ71402.1 - 0.52 9.8 4.9 0.93 9.0 3.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Shisa PF13908.1 KNZ71402.1 - 0.59 10.2 3.3 1.7 8.8 0.0 2.9 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator DLH PF01738.13 KNZ71403.1 - 1.2e-17 63.9 0.0 1.8e-17 63.3 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KNZ71403.1 - 0.0038 17.0 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.4 KNZ71403.1 - 0.1 11.4 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Acetyltransf_10 PF13673.1 KNZ71404.1 - 2.4e-05 24.4 0.0 8.1e-05 22.7 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KNZ71404.1 - 4.1e-05 23.6 0.0 0.0001 22.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ71404.1 - 0.035 14.1 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Elong_Iki1 PF10483.4 KNZ71405.1 - 6.1e-11 42.2 0.0 1.7e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 Elongator subunit Iki1 YpzG PF14139.1 KNZ71406.1 - 0.096 12.6 1.8 14 5.7 0.0 3.2 3 0 0 3 3 3 0 YpzG-like protein Aminotran_1_2 PF00155.16 KNZ71407.1 - 1.8e-90 303.5 0.0 2e-90 303.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II tRNA-synt_2 PF00152.15 KNZ71408.1 - 2.8e-78 263.0 0.1 4.1e-78 262.5 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KNZ71408.1 - 2.5e-07 30.4 0.0 4.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KNZ71408.1 - 0.036 13.2 3.1 1.1 8.4 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Pil1 PF13805.1 KNZ71409.1 - 6.4e-19 68.1 0.9 9.6e-19 67.5 0.6 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 IF4E PF01652.13 KNZ71410.1 - 9.9e-49 165.0 0.0 1.3e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mito_carr PF00153.22 KNZ71411.1 - 3.8e-56 186.8 0.0 5.6e-17 61.2 0.0 3.7 2 2 1 3 3 3 3 Mitochondrial carrier protein PX PF00787.19 KNZ71412.1 - 8.1e-16 57.8 0.0 1.7e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 KNZ71412.1 - 7.1e-10 38.4 5.1 1.7e-09 37.1 3.5 1.6 1 0 0 1 1 1 1 SNARE domain DivIC PF04977.10 KNZ71412.1 - 6.3 6.3 7.1 0.77 9.2 1.5 2.1 3 0 0 3 3 3 0 Septum formation initiator Methyltransf_18 PF12847.2 KNZ71413.1 - 1.9e-08 34.8 0.0 3.3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ71413.1 - 2.2e-08 34.0 0.0 3.1e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ71413.1 - 0.0029 18.0 0.0 0.0059 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KNZ71413.1 - 0.0034 16.9 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 KNZ71413.1 - 0.0082 16.6 0.0 0.028 14.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ71413.1 - 0.014 14.9 0.0 0.14 11.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 KNZ71413.1 - 0.026 13.2 0.0 0.067 11.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) CMAS PF02353.15 KNZ71413.1 - 0.035 13.1 0.0 0.53 9.3 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase CBS PF00571.23 KNZ71414.1 - 1.7e-29 101.3 2.8 5.2e-12 45.3 0.0 4.4 4 0 0 4 4 4 4 CBS domain SPRY PF00622.23 KNZ71415.1 - 8.4e-18 64.6 0.0 1.6e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 SPRY domain RIO1 PF01163.17 KNZ71418.1 - 6.6e-48 162.5 0.0 1.1e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 KNZ71418.1 - 4.4e-34 116.3 0.1 8.4e-34 115.5 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 KNZ71418.1 - 1.9e-10 40.8 0.1 0.00056 19.7 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KNZ71418.1 - 6e-08 32.0 0.0 5.8e-07 28.7 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.7 KNZ71418.1 - 0.08 10.8 13.6 0.11 10.4 9.5 1.1 1 0 0 1 1 1 0 Nop14-like family HTH_Crp_2 PF13545.1 KNZ71418.1 - 0.11 12.2 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Lin-8 PF03353.10 KNZ71418.1 - 0.16 11.2 10.6 0.24 10.6 7.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF605 PF04652.11 KNZ71418.1 - 0.33 10.3 12.2 0.45 9.8 8.4 1.1 1 0 0 1 1 1 0 Vta1 like BSP_II PF05432.6 KNZ71418.1 - 0.41 9.8 16.7 0.042 13.1 8.6 1.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) SMN PF06003.7 KNZ71418.1 - 0.47 9.5 7.2 0.81 8.7 5.0 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) CDC45 PF02724.9 KNZ71418.1 - 0.72 7.8 11.7 0.97 7.3 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 KNZ71418.1 - 1.1 7.3 9.1 1.6 6.8 6.3 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein NOA36 PF06524.7 KNZ71418.1 - 4.5 6.4 7.4 6.4 5.9 5.1 1.2 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.8 KNZ71418.1 - 6.5 5.3 16.5 10 4.7 11.4 1.3 1 0 0 1 1 1 0 Paf1 Acetyltransf_1 PF00583.19 KNZ71419.1 - 7.8e-13 48.2 0.0 5.7e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KNZ71419.1 - 2.6e-08 33.8 0.0 4.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNZ71419.1 - 2.8e-05 24.1 0.0 0.00012 22.2 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KNZ71419.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ESSS PF10183.4 KNZ71420.1 - 2.2e-27 95.4 0.3 2.7e-27 95.2 0.2 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GCV_H PF01597.14 KNZ71421.1 - 9.4e-40 135.0 0.1 1.1e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 KNZ71421.1 - 1.1e-05 24.9 0.1 2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 KNZ71421.1 - 2.9e-05 23.7 0.1 4.8e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.17 KNZ71421.1 - 0.025 14.6 0.1 1.1 9.4 0.0 2.2 1 1 1 2 2 2 0 Peptidase family M23 GTP_EFTU PF00009.22 KNZ71422.1 - 1.2e-59 200.9 0.3 1.8e-59 200.3 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KNZ71422.1 - 2.5e-27 94.9 0.0 1.3e-26 92.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KNZ71422.1 - 9.4e-16 57.6 1.1 1.9e-15 56.6 0.8 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KNZ71422.1 - 2.1e-05 24.4 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KNZ71422.1 - 0.0021 18.5 0.0 0.0036 17.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 KNZ71422.1 - 0.011 15.4 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 4 cobW PF02492.14 KNZ71422.1 - 0.019 14.4 0.3 0.05 13.0 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KNZ71422.1 - 0.041 13.3 0.5 7.2 6.0 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DisA_N PF02457.11 KNZ71422.1 - 0.054 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding CbiA PF01656.18 KNZ71422.1 - 0.17 11.2 1.1 5.9 6.2 0.0 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain GRIP PF01465.15 KNZ71423.1 - 1e-18 66.5 1.1 4.1e-18 64.6 0.8 2.1 1 0 0 1 1 1 1 GRIP domain Pex14_N PF04695.8 KNZ71423.1 - 1.1e-16 61.1 1.1 1.1e-16 61.1 0.8 6.4 5 3 0 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Med5 PF08689.5 KNZ71424.1 - 4.3e-24 84.3 7.8 8.9e-21 73.3 1.8 3.1 3 0 0 3 3 3 3 Mediator complex subunit Med5 Cation_efflux PF01545.16 KNZ71425.1 - 1.8e-78 263.5 8.7 2.2e-78 263.2 6.0 1.1 1 0 0 1 1 1 1 Cation efflux family MerC PF03203.9 KNZ71425.1 - 0.17 12.2 6.2 4.2 7.7 0.6 3.0 1 1 1 2 2 2 0 MerC mercury resistance protein SMN PF06003.7 KNZ71426.1 - 3.5e-09 36.1 2.8 4.7e-09 35.7 1.9 1.2 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 KNZ71426.1 - 1.7e-05 24.6 0.0 5.4e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Tudor domain Relaxase PF03432.9 KNZ71426.1 - 0.004 16.5 2.4 0.0079 15.6 1.7 1.4 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain BLVR PF06375.6 KNZ71426.1 - 0.054 13.3 9.7 0.024 14.4 5.0 1.6 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) OmpH PF03938.9 KNZ71426.1 - 0.32 10.9 11.9 0.12 12.2 3.4 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Rtf2 PF04641.7 KNZ71426.1 - 1.2 8.2 12.3 0.26 10.4 5.2 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger DUF3682 PF12446.3 KNZ71426.1 - 1.2 9.3 8.3 1.9 8.7 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) PDCD2_C PF04194.8 KNZ71426.1 - 1.3 8.5 7.1 0.44 10.1 3.1 1.5 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain FlaG PF03646.10 KNZ71426.1 - 1.6 8.9 12.8 2.7 8.1 4.8 2.3 2 0 0 2 2 2 0 FlaG protein Rsc14 PF08586.5 KNZ71426.1 - 2.1 8.8 4.8 41 4.7 2.8 2.3 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit JAB PF01398.16 KNZ71427.1 - 1e-11 44.6 0.0 2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DPBB_1 PF03330.13 KNZ71427.1 - 5.7e-08 32.6 0.0 1.5e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF4131 PF13567.1 KNZ71427.1 - 0.033 13.6 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) TFIIA PF03153.8 KNZ71427.1 - 0.65 9.8 7.4 1.2 8.9 5.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DPBB_1 PF03330.13 KNZ71428.1 - 3.6e-10 39.7 0.0 3.8e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 KNZ71428.1 - 0.061 13.3 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 Cerato-platanin Barwin PF00967.12 KNZ71428.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Barwin family Ipi1_N PF12333.3 KNZ71429.1 - 9.1e-14 51.2 0.0 1.3e-12 47.5 0.0 2.9 2 1 2 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation DSS1_SEM1 PF05160.8 KNZ71429.1 - 0.081 12.7 0.5 0.16 11.7 0.3 1.4 1 0 0 1 1 1 0 DSS1/SEM1 family WEMBL PF05701.6 KNZ71430.1 - 0.12 10.7 5.0 0.19 10.1 3.4 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Cellulase PF00150.13 KNZ71431.1 - 1.5e-17 63.6 0.5 2.5e-17 63.0 0.3 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 KNZ71431.1 - 0.0017 17.5 0.1 0.012 14.8 0.1 2.0 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_10 PF00331.15 KNZ71431.1 - 0.0022 17.0 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Atracotoxin PF05353.6 KNZ71431.1 - 0.049 13.4 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Delta Atracotoxin E1_DerP2_DerF2 PF02221.10 KNZ71433.1 - 3e-22 79.3 0.1 3.8e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KNZ71433.1 - 5.2e-05 23.3 0.0 0.00013 22.0 0.0 1.6 1 1 1 2 2 2 1 ML-like domain Zip PF02535.17 KNZ71434.1 - 0.00056 19.0 0.0 0.00072 18.6 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter MRAP PF15183.1 KNZ71434.1 - 0.0018 17.8 0.0 0.0052 16.3 0.0 1.8 1 0 0 1 1 1 1 Melanocortin-2 receptor accessory protein family Tetraspannin PF00335.15 KNZ71434.1 - 1.6 7.9 12.7 7.2 5.8 8.8 2.1 1 1 0 1 1 1 0 Tetraspanin family Ribosomal_L17 PF01196.14 KNZ71437.1 - 2.9e-35 120.7 0.0 6.1e-35 119.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 SGL PF08450.7 KNZ71438.1 - 3.1e-70 236.3 0.0 3.7e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KNZ71438.1 - 9.8e-06 25.4 0.0 0.00013 21.8 0.0 2.2 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.11 KNZ71438.1 - 0.089 12.8 0.0 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 Strictosidine synthase DUF4221 PF13970.1 KNZ71438.1 - 0.089 12.0 0.1 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4221) Ribosomal_L13 PF00572.13 KNZ71439.1 - 3.6e-27 94.9 0.0 5.4e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L13 KH_1 PF00013.24 KNZ71440.1 - 1e-39 133.9 10.5 1.8e-15 56.2 0.2 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KNZ71440.1 - 3.9e-26 90.1 12.3 3.1e-09 36.2 1.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KNZ71440.1 - 9.7e-11 41.1 0.4 0.0039 16.8 0.0 3.6 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 KNZ71440.1 - 7.4e-09 35.0 7.3 0.011 15.2 0.1 3.6 4 0 0 4 4 4 3 KH domain KH_5 PF13184.1 KNZ71440.1 - 0.00014 21.6 2.8 0.29 10.9 0.0 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 KNZ71440.1 - 0.0016 17.9 0.9 0.42 10.0 0.0 2.7 3 0 0 3 3 3 2 dUTPase Arb2 PF09757.4 KNZ71440.1 - 0.15 11.5 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 Arb2 domain NUFIP1 PF10453.4 KNZ71441.1 - 5.6e-16 57.7 1.5 5.6e-16 57.7 1.0 1.8 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) IDO PF01231.13 KNZ71442.1 - 2.6e-114 381.9 0.0 3e-114 381.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Peptidase_M16_C PF05193.16 KNZ71443.1 - 3.2e-19 69.3 0.0 5.2e-12 45.8 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KNZ71443.1 - 8.8e-09 35.2 0.0 6.5e-08 32.4 0.0 2.4 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) MCM_N PF14551.1 KNZ71443.1 - 0.14 12.7 0.0 9.3 6.7 0.0 2.8 2 1 0 2 2 2 0 MCM N-terminal domain DUF2205 PF10224.4 KNZ71443.1 - 0.42 10.2 3.1 0.54 9.8 0.7 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Exo_endo_phos PF03372.18 KNZ71444.1 - 5.1e-19 69.1 0.0 9e-19 68.3 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LSM14 PF12701.2 KNZ71444.1 - 0.098 12.4 0.0 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Scd6-like Sm domain RhoGEF PF00621.15 KNZ71445.1 - 2.9e-17 63.1 0.0 4.9e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Fungal_trans PF04082.13 KNZ71447.1 - 6.2e-08 31.8 0.1 1.2e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ71447.1 - 4.1e-06 26.5 10.8 7.3e-06 25.7 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-3CxxC PF13695.1 KNZ71449.1 - 0.089 13.0 1.9 0.15 12.2 1.3 1.3 1 0 0 1 1 1 0 Zinc-binding domain Ras PF00071.17 KNZ71450.1 - 9.9e-48 161.5 0.1 1.1e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ71450.1 - 2.3e-14 53.9 0.0 3.3e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KNZ71450.1 - 0.00026 20.4 0.0 0.00059 19.3 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 KNZ71450.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KNZ71450.1 - 0.0019 18.1 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KNZ71450.1 - 0.0029 16.9 0.1 0.085 12.1 0.0 2.5 1 1 1 3 3 3 1 Ferrous iron transport protein B NB-ARC PF00931.17 KNZ71450.1 - 0.033 13.0 0.0 0.2 10.4 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.7 KNZ71450.1 - 0.044 12.9 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KNZ71450.1 - 0.045 13.9 0.1 1.7 8.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF374 PF04028.8 KNZ71450.1 - 0.086 12.0 0.0 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Yippee-Mis18 PF03226.9 KNZ71451.1 - 3.4e-21 75.0 0.2 3.8e-21 74.9 0.2 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 KNZ71451.1 - 0.021 14.7 1.5 0.71 9.8 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Evr1_Alr PF04777.8 KNZ71451.1 - 0.046 13.6 0.4 1 9.3 0.0 2.0 1 1 1 2 2 2 0 Erv1 / Alr family AlcCBM31 PF11606.3 KNZ71451.1 - 0.06 13.3 0.1 1.8 8.5 0.0 2.1 1 1 0 2 2 2 0 Family 31 carbohydrate binding protein Helicase_C PF00271.26 KNZ71452.1 - 1.4e-13 50.4 0.0 3.3e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KNZ71452.1 - 2.4e-07 30.3 0.0 9.1e-07 28.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KNZ71452.1 - 8.2e-06 25.7 0.0 2.6e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Beta_elim_lyase PF01212.16 KNZ71454.1 - 1.1e-70 238.0 0.0 1.7e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KNZ71454.1 - 0.00016 20.0 0.0 0.00029 19.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KNZ71454.1 - 0.09 11.7 0.0 0.24 10.3 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family zf-met2 PF12907.2 KNZ71455.1 - 2.3e-15 56.2 0.4 3e-15 55.8 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 KNZ71455.1 - 6.5e-05 23.5 12.5 9.8e-05 23.0 8.7 1.3 1 0 0 1 1 1 1 4F5 protein family zf-Tim10_DDP PF02953.10 KNZ71456.1 - 4.4e-21 73.9 0.6 5e-21 73.7 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KNZ71456.1 - 0.048 13.1 0.5 0.067 12.6 0.3 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF2116 PF09889.4 KNZ71456.1 - 0.15 11.8 1.4 0.23 11.2 1.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) WD40 PF00400.27 KNZ71457.1 - 1.2e-14 53.5 28.9 0.00036 20.3 0.0 9.0 9 0 0 9 9 9 5 WD domain, G-beta repeat DUF3312 PF11768.3 KNZ71457.1 - 0.25 9.5 0.0 0.39 8.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Mpv17_PMP22 PF04117.7 KNZ71458.1 - 8.6e-25 86.1 0.2 9.9e-25 85.9 0.1 1.0 1 0 0 1 1 1 1 Mpv17 / PMP22 family PTH2 PF01981.11 KNZ71460.1 - 5.5e-41 138.8 0.1 7.6e-41 138.4 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DEAD PF00270.24 KNZ71461.1 - 1.3e-36 125.6 0.1 2.4e-36 124.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ71461.1 - 3.3e-21 74.9 0.0 7e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KNZ71461.1 - 6.7e-20 70.4 0.3 1.5e-19 69.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.1 KNZ71461.1 - 0.073 13.2 1.4 0.83 9.8 0.3 3.0 2 1 0 2 2 2 0 AAA domain UPF0121 PF03661.8 KNZ71462.1 - 3.6e-19 68.9 5.0 4.9e-19 68.5 3.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) CBS PF00571.23 KNZ71463.1 - 6.4e-37 125.0 8.8 7.3e-10 38.4 0.0 4.8 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 KNZ71463.1 - 3.5e-08 32.9 0.0 1.2e-07 31.2 0.0 2.0 2 1 0 2 2 2 1 PB1 domain KaiC PF06745.8 KNZ71463.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 KaiC Sgf11 PF08209.6 KNZ71464.1 - 1.5e-12 46.6 0.5 3.2e-12 45.5 0.3 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 KNZ71464.1 - 0.35 10.5 1.9 0.36 10.5 0.1 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-RING_5 PF14634.1 KNZ71464.1 - 0.53 10.0 2.9 3.3 7.5 0.3 2.3 2 0 0 2 2 2 0 zinc-RING finger domain PTH2 PF01981.11 KNZ71465.1 - 4.2e-41 139.2 0.1 4.6e-41 139.1 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SNARE PF05739.14 KNZ71467.1 - 1.8e-08 33.9 0.5 2.3e-08 33.5 0.3 1.2 1 0 0 1 1 1 1 SNARE domain DUF4234 PF14018.1 KNZ71467.1 - 0.0029 17.3 0.6 0.0045 16.7 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4234) DUF2120 PF09893.4 KNZ71467.1 - 0.074 13.0 0.0 0.097 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Synaptobrevin PF00957.16 KNZ71467.1 - 0.35 10.5 2.1 0.29 10.7 0.3 1.7 2 0 0 2 2 2 0 Synaptobrevin Peptidase_C48 PF02902.14 KNZ71468.1 - 5.1e-20 72.0 0.0 9.9e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain G-patch PF01585.18 KNZ71469.1 - 1.5e-11 43.9 0.2 3e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.3 KNZ71469.1 - 1.3e-06 28.3 6.4 2.3e-06 27.5 4.5 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KNZ71469.1 - 1.7e-05 24.8 1.3 2.8e-05 24.1 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.2 KNZ71469.1 - 0.0003 20.5 0.0 0.0003 20.5 0.0 2.3 3 0 0 3 3 3 1 DExH-box splicing factor binding site zf-C2H2_2 PF12756.2 KNZ71469.1 - 0.0014 18.6 0.7 0.0024 17.9 0.5 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) NusB PF01029.13 KNZ71469.1 - 0.092 12.7 0.9 0.17 11.8 0.6 1.4 1 0 0 1 1 1 0 NusB family XAP5 PF04921.9 KNZ71469.1 - 2.7 7.5 10.7 8.1 5.9 3.1 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator Frataxin_Cyay PF01491.11 KNZ71471.1 - 1.6e-33 114.7 0.0 1.8e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain Drf_DAD PF06345.6 KNZ71471.1 - 0.17 11.7 0.4 0.39 10.6 0.3 1.6 1 0 0 1 1 1 0 DRF Autoregulatory Domain Urb2 PF10441.4 KNZ71472.1 - 8.3e-30 104.0 0.0 8.3e-30 104.0 0.0 2.5 3 0 0 3 3 3 1 Urb2/Npa2 family WHIM1 PF15612.1 KNZ71472.1 - 0.13 12.2 1.9 16 5.7 0.1 3.4 3 0 0 3 3 3 0 WSTF, HB1, Itc1p, MBD9 motif 1 IBR PF01485.16 KNZ71473.1 - 1.9e-18 66.0 28.1 2.7e-10 39.9 1.2 3.4 3 0 0 3 3 3 2 IBR domain RWD PF05773.17 KNZ71473.1 - 5.8e-08 32.6 0.0 1.3e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 KNZ71473.1 - 8.6e-06 25.4 8.0 8.6e-06 25.4 5.5 4.5 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KNZ71473.1 - 0.00017 21.5 9.4 0.00017 21.5 6.5 5.4 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ71473.1 - 0.00062 19.3 6.8 0.00062 19.3 4.7 4.8 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) KH_1 PF00013.24 KNZ71474.1 - 5.1e-37 125.3 0.1 8.8e-09 34.8 0.0 6.2 6 0 0 6 6 6 4 KH domain KH_3 PF13014.1 KNZ71474.1 - 4.3e-25 86.8 0.2 5.7e-06 25.8 0.0 6.3 6 0 0 6 6 6 4 KH domain V-ATPase_C PF03223.10 KNZ71475.1 - 2.4e-116 388.6 1.4 2.7e-116 388.5 1.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Rhodanese PF00581.15 KNZ71476.1 - 6.1e-21 74.8 0.0 1.5e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain ThiC-associated PF13667.1 KNZ71476.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 ThiC-associated domain Ctr PF04145.10 KNZ71480.1 - 1.1e-26 93.6 0.0 1.4e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family ATP_synt_I PF03899.10 KNZ71480.1 - 3.4 7.8 9.3 0.95 9.6 0.2 2.1 2 0 0 2 2 2 0 ATP synthase I chain Rhodanese PF00581.15 KNZ71481.1 - 5e-17 62.2 0.0 2.1e-16 60.2 0.0 1.8 1 1 1 2 2 2 1 Rhodanese-like domain Multi_ubiq PF14452.1 KNZ71481.1 - 0.002 18.0 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 Multiubiquitin RRM_6 PF14259.1 KNZ71482.1 - 1.1e-07 31.7 0.0 1.1e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 KNZ71482.1 - 1.7e-06 27.5 4.8 2.8e-06 26.8 3.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 KNZ71482.1 - 9e-06 25.7 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 PWI domain RRM_5 PF13893.1 KNZ71482.1 - 0.002 17.9 0.0 0.0063 16.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KNZ71482.1 - 0.069 13.0 0.1 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif GMC_oxred_C PF05199.8 KNZ71483.1 - 0.061 13.6 0.3 0.093 13.0 0.2 1.4 1 1 0 1 1 1 0 GMC oxidoreductase Aminotran_4 PF01063.14 KNZ71485.1 - 3.2e-27 95.4 0.0 3.9e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV APH PF01636.18 KNZ71488.1 - 1.4e-12 47.9 0.3 2.7e-12 46.9 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ71488.1 - 2.3e-06 27.3 0.1 4.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KNZ71488.1 - 0.0013 17.9 0.0 0.3 10.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.17 KNZ71488.1 - 0.012 14.9 0.1 0.14 11.5 0.0 2.2 2 1 1 3 3 3 0 RIO1 family Fructosamin_kin PF03881.9 KNZ71488.1 - 0.08 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase Aldedh PF00171.17 KNZ71489.1 - 5.4e-180 598.6 0.7 6.1e-180 598.4 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KNZ71489.1 - 0.0014 17.4 0.0 0.0046 15.7 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KNZ71489.1 - 0.018 14.2 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) ADH_zinc_N PF00107.21 KNZ71490.1 - 1.4e-24 86.1 0.1 2.3e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PAP_assoc PF03828.14 KNZ71491.1 - 6.6e-07 29.1 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KNZ71491.1 - 8.4e-07 29.2 0.0 2.1e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyltransferase domain Sp38 PF07354.7 KNZ71493.1 - 0.59 8.7 7.2 0.73 8.4 5.0 1.1 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) RVP_2 PF08284.6 KNZ71497.1 - 0.0012 18.7 0.0 0.0015 18.4 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease GerPB PF10803.3 KNZ71497.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Spore germination GerPB DUF4262 PF14081.1 KNZ71497.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) ApbE PF02424.10 KNZ71499.1 - 0.041 13.1 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 ApbE family Transp_cyt_pur PF02133.10 KNZ71501.1 - 0.081 11.4 0.0 0.081 11.4 0.0 1.2 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin Coat_X PF07552.6 KNZ71501.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Spore Coat Protein X and V domain Abhydrolase_6 PF12697.2 KNZ71502.1 - 6.4e-11 42.5 0.0 8.3e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ71502.1 - 3e-05 23.7 0.0 6.3e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chromo PF00385.19 KNZ71503.1 - 5.2e-18 64.4 0.1 6.3e-18 64.1 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KNZ71503.1 - 0.058 13.2 0.2 0.078 12.8 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 GED PF02212.13 KNZ71504.1 - 0.031 14.1 0.2 0.07 13.0 0.1 1.6 1 0 0 1 1 1 0 Dynamin GTPase effector domain AAA_22 PF13401.1 KNZ71504.1 - 0.055 13.6 0.0 14 5.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain E1_dh PF00676.15 KNZ71505.1 - 3e-110 367.6 0.0 3.5e-110 367.4 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KNZ71505.1 - 1.5e-05 24.1 0.0 2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 KNZ71505.1 - 0.00018 21.1 0.6 0.00018 21.1 0.4 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Beta_elim_lyase PF01212.16 KNZ71505.1 - 0.017 14.2 0.2 0.04 13.0 0.0 1.8 2 1 0 2 2 2 0 Beta-eliminating lyase Transketolase_N PF00456.16 KNZ71505.1 - 0.071 11.9 0.2 0.13 11.0 0.0 1.5 2 0 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain PIF1 PF05970.9 KNZ71506.1 - 6.5e-34 117.4 0.0 7.3e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Asp_protease_2 PF13650.1 KNZ71510.1 - 0.0019 18.6 0.0 0.0045 17.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease NSP10 PF09401.5 KNZ71510.1 - 0.012 15.2 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA synthesis protein NSP10 Asp_protease PF09668.5 KNZ71510.1 - 0.099 12.2 0.1 0.2 11.2 0.1 1.6 1 1 1 2 2 2 0 Aspartyl protease Ribonuclease_3 PF00636.21 KNZ71511.1 - 0.068 13.6 0.0 0.085 13.3 0.0 1.3 1 1 0 1 1 1 0 Ribonuclease III domain Methyltransf_2 PF00891.13 KNZ71512.1 - 3.8e-21 75.3 0.0 5.6e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase RPA_C PF08784.6 KNZ71512.1 - 0.017 15.4 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 Replication protein A C terminal Methyltransf_12 PF08242.7 KNZ71512.1 - 0.028 14.8 0.0 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ71512.1 - 0.032 14.8 0.0 0.078 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MarR_2 PF12802.2 KNZ71512.1 - 0.071 12.7 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 MarR family Dimerisation PF08100.6 KNZ71512.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Rrf2 PF02082.15 KNZ71512.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Spore_GerAC PF05504.6 KNZ71513.1 - 0.038 13.7 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal SMN PF06003.7 KNZ71515.1 - 0.13 11.3 0.8 0.17 10.9 0.6 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Mitofilin PF09731.4 KNZ71516.1 - 1.9e-81 274.4 19.2 2.1e-81 274.3 13.3 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF2937 PF11157.3 KNZ71516.1 - 0.67 9.2 6.0 2.1 7.6 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DHQ_synthase PF01761.15 KNZ71517.1 - 3.3e-35 121.2 0.3 5.7e-35 120.5 0.2 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase USP8_interact PF08941.5 KNZ71517.1 - 0.003 16.9 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 USP8 interacting SPT2 PF08243.6 KNZ71519.1 - 4.6 7.5 8.4 0.85 9.9 2.7 2.0 2 0 0 2 2 2 0 SPT2 chromatin protein Pyr_redox_3 PF13738.1 KNZ71520.1 - 2.2e-20 73.5 0.0 3.9e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KNZ71520.1 - 2.3e-13 49.2 0.0 4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KNZ71520.1 - 2.4e-10 40.2 0.1 1.5e-09 37.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KNZ71520.1 - 3e-08 32.9 0.0 5.2e-05 22.3 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KNZ71520.1 - 3.8e-06 26.9 0.0 0.001 18.9 0.0 2.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KNZ71520.1 - 8.2e-06 24.9 0.0 0.0099 14.8 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KNZ71520.1 - 2e-05 24.4 0.1 0.0015 18.3 0.0 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 KNZ71520.1 - 0.0049 15.9 0.4 0.013 14.5 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KNZ71520.1 - 0.0053 17.1 0.8 2.4 8.6 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KNZ71520.1 - 0.024 13.5 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 KNZ71520.1 - 0.19 10.1 0.1 0.39 9.1 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 KNZ71520.1 - 0.22 10.6 0.0 0.46 9.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pex24p PF06398.6 KNZ71522.1 - 0.8 8.4 2.8 1.2 7.8 1.9 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Exo_endo_phos_2 PF14529.1 KNZ71523.1 - 0.0035 16.9 0.2 0.0057 16.2 0.2 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 KNZ71524.1 - 0.0008 18.8 0.0 0.00095 18.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pyr_redox_3 PF13738.1 KNZ71526.1 - 8.6e-08 32.4 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KNZ71526.1 - 7.6e-06 24.3 0.0 1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KNZ71526.1 - 0.00016 20.7 0.0 0.0069 15.3 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 KNZ71526.1 - 0.003 16.7 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KNZ71526.1 - 0.0094 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase OTT_1508_deam PF14441.1 KNZ71528.1 - 7e-06 25.9 0.0 1.8e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 OTT_1508-like deaminase DYW_deaminase PF14432.1 KNZ71528.1 - 0.031 14.2 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases OTT_1508_deam PF14441.1 KNZ71529.1 - 4.3e-08 33.0 0.3 1.2e-07 31.6 0.2 1.9 1 1 0 1 1 1 1 OTT_1508-like deaminase SusD PF07980.6 KNZ71529.1 - 0.026 14.0 0.2 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 SusD family SCHIP-1 PF10148.4 KNZ71529.1 - 0.045 13.1 0.1 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 BCIP PF13862.1 KNZ71530.1 - 7.8e-33 113.6 0.2 8.3e-32 110.2 0.0 2.0 2 0 0 2 2 2 1 p21-C-terminal region-binding protein PI3K_1B_p101 PF10486.4 KNZ71530.1 - 0.075 10.6 0.1 0.1 10.1 0.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Toprim_C_rpt PF13368.1 KNZ71530.1 - 0.73 10.3 4.1 10 6.7 0.1 2.5 2 0 0 2 2 2 0 Topoisomerase C-terminal repeat Pro_dh PF01619.13 KNZ71531.1 - 6.6e-35 120.6 0.0 6e-34 117.4 0.0 2.3 1 1 0 1 1 1 1 Proline dehydrogenase Sigma70_r3 PF04539.11 KNZ71532.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 DUF4411 PF14367.1 KNZ71532.1 - 2.9 7.5 6.9 0.35 10.5 0.3 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4411) COesterase PF00135.23 KNZ71533.1 - 4.2e-07 29.0 0.0 5.9e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Coprogen_oxidas PF01218.13 KNZ71534.1 - 1.2e-114 381.9 0.0 2.4e-114 380.8 0.0 1.5 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase SAICAR_synt PF01259.13 KNZ71535.1 - 3e-85 285.3 0.0 3.8e-85 284.9 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Diphthamide_syn PF01866.12 KNZ71537.1 - 1.6e-54 185.2 0.3 2.3e-33 115.7 0.0 2.5 2 1 0 2 2 2 2 Putative diphthamide synthesis protein tRNA-synt_2 PF00152.15 KNZ71540.1 - 0.083 11.6 0.3 0.095 11.4 0.2 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Phage_integrase PF00589.17 KNZ71542.1 - 1e-05 25.3 0.0 5.6e-05 22.8 0.0 2.2 2 1 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.12 KNZ71542.1 - 0.095 12.8 0.0 0.31 11.2 0.0 1.9 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Glyco_hydro_31 PF01055.21 KNZ71545.1 - 1.9e-122 409.2 0.3 2.5e-122 408.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KNZ71545.1 - 8.5e-11 41.5 0.2 1.7e-09 37.3 0.0 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like Cmc1 PF08583.5 KNZ71546.1 - 4.2e-14 52.0 2.3 5e-14 51.8 1.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Muted PF14942.1 KNZ71546.1 - 0.018 14.9 0.4 0.02 14.7 0.3 1.0 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Cation_ATPase_N PF00690.21 KNZ71546.1 - 0.12 11.8 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Transketolase_N PF00456.16 KNZ71547.1 - 5.5e-143 475.7 0.0 7e-143 475.4 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KNZ71547.1 - 3.6e-42 143.8 0.0 7.4e-42 142.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KNZ71547.1 - 1.5e-12 47.5 0.0 3.1e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KNZ71547.1 - 7.8e-05 21.7 0.3 0.00071 18.5 0.2 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 KNZ71547.1 - 0.0019 17.0 0.0 0.0027 16.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component UCR_14kD PF02271.11 KNZ71548.1 - 1.3e-36 124.5 0.4 1.5e-36 124.3 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit NDK PF00334.14 KNZ71549.1 - 3.4e-56 188.7 0.0 4e-56 188.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DOMON PF03351.12 KNZ71550.1 - 1.3e-05 25.1 0.3 7.9e-05 22.5 0.0 2.3 2 1 0 2 2 2 1 DOMON domain Cytochrom_B561 PF03188.11 KNZ71550.1 - 0.011 15.6 6.2 0.026 14.3 4.3 1.8 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 DUF3180 PF11377.3 KNZ71550.1 - 0.015 15.1 0.2 0.044 13.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3180) DUF2530 PF10745.4 KNZ71550.1 - 1.5 8.8 6.5 4.2 7.4 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) DUF2427 PF10348.4 KNZ71550.1 - 2.3 7.8 7.5 0.16 11.5 0.3 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF2427) Pyridoxal_deC PF00282.14 KNZ71551.1 - 4.5e-55 186.5 0.0 2e-54 184.5 0.0 1.7 1 1 1 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KNZ71551.1 - 3e-05 22.9 0.0 4.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 KNZ71551.1 - 0.13 10.7 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Pyridoxal_deC PF00282.14 KNZ71554.1 - 1.9e-62 210.8 0.0 2.6e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KNZ71554.1 - 1.3e-06 27.4 0.0 2.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V 4HBT PF03061.17 KNZ71555.1 - 2.5e-09 37.1 0.0 3.5e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 KNZ71555.1 - 8.7e-06 26.1 0.0 1.1e-05 25.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 KNZ71555.1 - 0.0015 17.5 0.2 0.0022 16.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase DUF2346 PF09803.4 KNZ71556.1 - 1.4e-09 37.6 0.0 1.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) PALP PF00291.20 KNZ71557.1 - 1.5e-51 175.4 0.0 2e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PIN_4 PF13638.1 KNZ71558.1 - 7.3e-21 74.6 0.0 1.7e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.4 KNZ71558.1 - 2e-10 40.3 0.0 1.7e-09 37.3 0.0 2.6 3 1 0 3 3 3 1 Est1 DNA/RNA binding domain zf-RVT PF13966.1 KNZ71559.1 - 0.0011 19.2 0.3 0.0011 19.2 0.2 2.2 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase DNA_pol_E_B PF04042.11 KNZ71560.1 - 6e-34 117.1 0.0 9.5e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B EAP30 PF04157.11 KNZ71561.1 - 1.4e-55 187.9 0.0 1.6e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DUF4423 PF14394.1 KNZ71561.1 - 0.0063 16.0 0.2 0.051 13.1 0.0 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4423) FtsA PF14450.1 KNZ71561.1 - 0.1 12.4 0.2 0.67 9.8 0.0 2.1 2 0 0 2 2 2 0 Cell division protein FtsA Cellulase PF00150.13 KNZ71563.1 - 2.9e-23 82.4 2.0 4.5e-23 81.8 1.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Imm33 PF15580.1 KNZ71563.1 - 0.075 12.5 3.3 0.2 11.1 2.3 1.6 1 0 0 1 1 1 0 Immunity protein 33 Hid1 PF12722.2 KNZ71564.1 - 4.3e-145 484.6 0.0 4e-144 481.4 0.0 1.8 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KNZ71564.1 - 1e-71 242.0 0.0 1.4e-71 241.5 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Thioredoxin_9 PF14595.1 KNZ71564.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Rad51 PF08423.6 KNZ71565.1 - 6.7e-20 71.0 0.0 1.2e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KNZ71565.1 - 2.3e-07 30.4 0.0 8e-07 28.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 KNZ71565.1 - 7.5e-05 21.9 0.3 0.0021 17.1 0.1 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein KaiC PF06745.8 KNZ71565.1 - 0.00025 20.2 0.0 0.00041 19.5 0.0 1.3 1 0 0 1 1 1 1 KaiC Atg8 PF02991.11 KNZ71566.1 - 4.1e-52 174.4 0.2 4.9e-52 174.2 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KNZ71566.1 - 3.3e-07 30.4 0.0 4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Band_7 PF01145.20 KNZ71567.1 - 0.00026 20.9 11.2 0.0012 18.8 5.5 2.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family Lactamase_B_2 PF12706.2 KNZ71568.1 - 4.9e-18 65.3 0.3 8.7e-18 64.5 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KNZ71568.1 - 5.5e-07 29.4 0.0 9.6e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.10 KNZ71568.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II MFS_1 PF07690.11 KNZ71569.1 - 5.1e-35 120.8 33.2 5.1e-35 120.8 23.0 2.0 1 1 2 3 3 3 2 Major Facilitator Superfamily Pkinase PF00069.20 KNZ71570.1 - 2.1e-63 213.9 0.0 2.4e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ71570.1 - 1.7e-25 89.6 0.0 2.2e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ71570.1 - 9.8e-06 24.7 0.0 3.3e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KNZ71570.1 - 0.00074 19.3 0.1 0.03 14.0 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ71570.1 - 0.0076 15.8 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase WD40 PF00400.27 KNZ71571.1 - 1.1e-63 208.9 33.3 1.5e-10 40.5 0.2 8.2 7 2 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KNZ71571.1 - 3.4e-16 58.5 13.3 7.1e-05 21.1 0.0 6.0 1 1 4 5 5 5 5 Nucleoporin Nup120/160 F-box-like PF12937.2 KNZ71571.1 - 6e-12 45.0 0.2 1.3e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ71571.1 - 1.1e-09 37.6 0.0 2.4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain Thoc2 PF11732.3 KNZ71573.1 - 0.018 14.8 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Kelch_6 PF13964.1 KNZ71573.1 - 0.11 12.7 0.9 0.35 11.1 0.6 2.0 1 1 0 1 1 1 0 Kelch motif UQ_con PF00179.21 KNZ71576.1 - 5.2e-11 42.1 0.4 9.4e-09 34.8 0.4 2.2 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme ALO PF04030.9 KNZ71577.1 - 2.1e-74 250.3 4.2 4.2e-74 249.3 2.9 1.5 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KNZ71577.1 - 6.8e-05 22.3 0.4 0.00016 21.2 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain Sen15 PF09631.5 KNZ71578.1 - 0.038 14.2 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 Sen15 protein PapG_C PF03628.8 KNZ71579.1 - 0.035 13.7 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 PapG chaperone-binding domain DUF2971 PF11185.3 KNZ71579.1 - 0.061 14.0 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2971) T4_deiodinase PF00837.12 KNZ71584.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Iodothyronine deiodinase WD40 PF00400.27 KNZ71584.1 - 0.11 12.3 8.0 0.22 11.4 0.1 3.0 3 1 0 3 3 3 0 WD domain, G-beta repeat Peptidase_C54 PF03416.14 KNZ71586.1 - 5.6e-88 294.7 0.0 7.6e-88 294.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 p450 PF00067.17 KNZ71587.1 - 2.7e-58 197.6 0.0 3.8e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PAGK PF15284.1 KNZ71587.1 - 0.051 13.3 0.2 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Phage-encoded virulence factor FAM150 PF15129.1 KNZ71588.1 - 0.093 12.6 0.2 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 FAM150 family MFS_1 PF07690.11 KNZ71589.1 - 0.00047 18.9 8.8 0.0005 18.8 6.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily FA_desaturase PF00487.19 KNZ71589.1 - 0.89 8.9 5.6 2.1 7.6 3.9 1.6 1 1 0 1 1 1 0 Fatty acid desaturase Rot1 PF10681.4 KNZ71590.1 - 0.19 11.0 1.1 0.18 11.1 0.8 1.1 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal Ribonuclease_3 PF00636.21 KNZ71591.1 - 5.7e-39 133.1 0.0 3.3e-19 69.3 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KNZ71591.1 - 8e-26 90.4 0.5 8.1e-11 41.9 0.0 4.5 4 0 0 4 4 4 4 Ribonuclease-III-like DEAD PF00270.24 KNZ71591.1 - 2.7e-15 56.2 0.0 8.3e-15 54.6 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.9 KNZ71591.1 - 2.5e-13 49.6 0.0 5.6e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 KNZ71591.1 - 1.7e-12 47.0 0.0 4.7e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ71591.1 - 5.6e-11 42.6 0.0 1.3e-10 41.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PvlArgDC PF01862.11 KNZ71591.1 - 0.2 11.2 0.0 0.51 9.9 0.0 1.6 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Peroxidase_2 PF01328.12 KNZ71592.1 - 1.4e-22 79.8 0.0 1.9e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Zot PF05707.7 KNZ71592.1 - 0.014 14.8 0.0 0.019 14.4 0.0 1.3 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) adh_short PF00106.20 KNZ71593.1 - 5.8e-23 81.6 0.2 7.2e-23 81.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ71593.1 - 6.9e-09 35.8 0.0 8.8e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ71593.1 - 1.5e-06 27.9 0.0 2.1e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KNZ71593.1 - 2.6e-05 23.4 0.0 3.6e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KNZ71593.1 - 4.4e-05 23.0 0.0 6.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KNZ71593.1 - 0.00084 18.3 0.1 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KNZ71593.1 - 0.0026 17.8 0.1 0.0049 16.9 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KNZ71593.1 - 0.0028 16.9 0.1 0.0039 16.4 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 KNZ71593.1 - 0.039 12.8 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Protoglobin PF11563.3 KNZ71594.1 - 8.1e-43 145.8 0.0 9.4e-43 145.6 0.0 1.0 1 0 0 1 1 1 1 Protoglobin p450 PF00067.17 KNZ71595.1 - 1.2e-61 208.6 0.0 1.6e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_30 PF02055.11 KNZ71597.1 - 4e-33 114.3 0.5 5.6e-33 113.8 0.3 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 KNZ71597.1 - 0.0016 17.4 0.0 0.072 12.0 0.0 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 MFS_1 PF07690.11 KNZ71599.1 - 6.4e-40 136.9 34.3 6.4e-40 136.9 23.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily NABP PF07990.7 KNZ71599.1 - 0.12 11.6 0.6 0.18 11.0 0.4 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Bacteriocin_IId PF09221.5 KNZ71599.1 - 3.6 7.5 7.4 12 5.9 0.2 2.8 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like Fasciclin PF02469.17 KNZ71600.1 - 1.4e-30 105.9 1.8 1e-18 67.5 0.2 2.2 2 0 0 2 2 2 2 Fasciclin domain ABC2_membrane_3 PF12698.2 KNZ71601.1 - 0.29 10.1 9.9 0.5 9.3 6.9 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane PF01061.19 KNZ71601.1 - 7.4 5.6 14.0 0.55 9.3 5.7 1.8 2 0 0 2 2 2 0 ABC-2 type transporter F-box-like PF12937.2 KNZ71602.1 - 8.6e-08 31.7 1.2 3.2e-07 29.9 0.9 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KNZ71603.1 - 2e-05 24.1 1.3 7.1e-05 22.4 0.9 2.0 1 0 0 1 1 1 1 F-box-like PP2C PF00481.16 KNZ71604.1 - 1.6e-50 171.8 0.2 3e-50 170.9 0.1 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C HMG_box PF00505.14 KNZ71605.1 - 7.8e-08 32.4 4.0 1.7e-07 31.4 2.7 1.6 1 1 0 1 1 1 1 HMG (high mobility group) box adh_short PF00106.20 KNZ71606.1 - 6.6e-16 58.6 4.7 1.1e-14 54.7 3.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ71606.1 - 2.2e-12 47.2 0.4 1.4e-11 44.6 0.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KNZ71606.1 - 0.0068 15.5 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KNZ71606.1 - 0.015 15.3 0.7 0.053 13.5 0.3 2.1 1 1 0 1 1 1 0 NADH(P)-binding HMG_box PF00505.14 KNZ71610.1 - 6.6e-06 26.3 6.4 1.7e-05 24.9 4.4 1.7 1 1 0 1 1 1 1 HMG (high mobility group) box PNP_UDP_1 PF01048.15 KNZ71611.1 - 6.8e-24 84.1 0.1 1.1e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily DUF3715 PF12509.3 KNZ71611.1 - 0.071 12.9 0.0 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3715) HMG_box PF00505.14 KNZ71612.1 - 0.019 15.2 4.9 0.02 15.1 1.0 2.2 1 1 1 2 2 2 0 HMG (high mobility group) box HMG_box_2 PF09011.5 KNZ71612.1 - 0.035 14.4 2.3 0.31 11.4 0.9 2.2 1 1 1 2 2 2 0 HMG-box domain adh_short_C2 PF13561.1 KNZ71613.1 - 2.3e-28 99.5 0.0 3e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KNZ71613.1 - 2.5e-19 69.8 0.5 3.6e-19 69.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ71613.1 - 7.7e-10 38.7 0.1 1.1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KNZ71613.1 - 0.0057 15.6 0.0 0.0092 14.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase His_biosynth PF00977.16 KNZ71613.1 - 0.015 14.5 0.1 0.036 13.3 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein Flavodoxin_4 PF12682.2 KNZ71613.1 - 0.1 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin PA PF02225.17 KNZ71613.1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 PA domain WD40 PF00400.27 KNZ71614.1 - 9.7e-13 47.4 19.7 3.4e-05 23.5 0.3 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat BUD22 PF09073.5 KNZ71614.1 - 0.34 9.9 2.0 0.65 8.9 1.4 1.3 1 0 0 1 1 1 0 BUD22 GMC_oxred_N PF00732.14 KNZ71615.1 - 3.5e-56 190.5 0.0 5e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ71615.1 - 3.6e-36 124.5 0.2 5.6e-36 123.9 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KNZ71615.1 - 3.5e-06 26.1 0.2 8.9e-05 21.5 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KNZ71615.1 - 0.00018 21.4 0.1 0.00056 19.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KNZ71615.1 - 0.00062 18.7 0.1 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KNZ71615.1 - 0.0044 15.9 2.3 0.17 10.7 0.2 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.1 KNZ71615.1 - 0.023 14.7 0.1 3.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KNZ71615.1 - 0.031 13.3 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KNZ71615.1 - 0.12 11.5 0.6 0.24 10.4 0.1 1.8 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 KNZ71615.1 - 0.18 10.2 0.2 11 4.3 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Pkinase PF00069.20 KNZ71616.1 - 7.1e-71 238.3 0.0 1.5e-67 227.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ71616.1 - 1.5e-36 125.8 0.0 1.4e-32 112.8 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KNZ71616.1 - 0.00022 20.3 0.0 0.00079 18.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KNZ71616.1 - 0.0013 18.1 0.3 0.0043 16.4 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KNZ71616.1 - 0.0051 15.9 0.2 0.011 14.7 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family GMC_oxred_N PF00732.14 KNZ71618.1 - 6.3e-48 163.4 0.1 2.7e-47 161.3 0.1 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ71618.1 - 4.4e-36 124.3 0.2 6.7e-36 123.7 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KNZ71618.1 - 2.1e-05 23.5 5.4 4.4e-05 22.5 2.3 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KNZ71618.1 - 3.3e-05 23.8 0.4 8.5e-05 22.4 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KNZ71618.1 - 0.00078 18.3 2.4 0.013 14.3 0.4 2.4 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 KNZ71618.1 - 0.00082 18.3 0.0 0.0016 17.4 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KNZ71618.1 - 0.0075 16.3 0.0 1.3 9.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KNZ71618.1 - 0.016 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KNZ71618.1 - 0.037 13.1 0.1 0.093 11.8 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KNZ71618.1 - 0.039 13.8 0.1 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UCR_TM PF02921.9 KNZ71618.1 - 0.043 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region DUF2583 PF10762.4 KNZ71620.1 - 0.19 11.8 1.3 1.3 9.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) p450 PF00067.17 KNZ71621.1 - 1.1e-63 215.3 0.0 1.4e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 gag-asp_proteas PF13975.1 KNZ71623.1 - 8.8e-09 35.0 0.0 0.0023 17.7 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ71623.1 - 3.5e-05 24.2 0.0 0.023 15.2 0.0 2.3 2 0 0 2 2 2 2 Aspartyl protease YqjK PF13997.1 KNZ71624.1 - 0.23 11.6 6.8 0.36 11.0 0.1 3.6 3 1 1 4 4 4 0 YqjK-like protein Zn_clus PF00172.13 KNZ71624.1 - 2 8.4 8.7 9.2 6.2 6.3 1.9 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MRC1 PF09444.5 KNZ71626.1 - 1.5e-08 35.0 15.3 1.5e-08 35.0 10.6 4.8 4 1 2 6 6 6 1 MRC1-like domain SAGA-Tad1 PF12767.2 KNZ71627.1 - 0.0061 16.2 9.7 0.0082 15.8 6.7 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Draxin PF15550.1 KNZ71627.1 - 0.4 10.2 6.4 0.48 10.0 4.5 1.1 1 0 0 1 1 1 0 Draxin RhoGAP PF00620.22 KNZ71628.1 - 3.6e-40 137.0 0.0 6.2e-40 136.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 KNZ71628.1 - 1.3e-11 44.6 0.0 2.8e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KNZ71628.1 - 4.1e-07 30.2 0.0 9.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PX PF00787.19 KNZ71628.1 - 1.5e-06 27.9 0.0 3.9e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 PX domain PH_8 PF15409.1 KNZ71628.1 - 0.018 15.0 0.2 0.14 12.2 0.0 2.4 3 0 0 3 3 3 0 Pleckstrin homology domain SHR3_chaperone PF08229.6 KNZ71629.1 - 1.2e-31 109.2 1.2 5.8e-18 64.5 0.1 2.0 2 0 0 2 2 2 2 ER membrane protein SH3 LSM PF01423.17 KNZ71631.1 - 6.6e-15 54.4 0.0 8.3e-15 54.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain NMO PF03060.10 KNZ71632.1 - 1.2e-49 169.3 1.0 1.2e-47 162.7 0.7 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 KNZ71632.1 - 0.00063 18.6 0.2 0.0011 17.9 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KNZ71632.1 - 0.0015 17.4 0.0 0.075 11.9 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KNZ71632.1 - 0.0018 17.5 0.1 0.84 8.8 0.0 2.2 2 0 0 2 2 2 2 Histidine biosynthesis protein CPSase_L_D2 PF02786.12 KNZ71633.1 - 2.4e-80 268.7 0.1 4.7e-80 267.8 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KNZ71633.1 - 4.3e-66 222.0 0.0 7.8e-66 221.2 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KNZ71633.1 - 4.6e-37 126.4 0.1 1.1e-36 125.2 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KNZ71633.1 - 1.4e-29 102.1 0.0 4.5e-29 100.5 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KNZ71633.1 - 3.7e-28 98.7 0.0 7.1e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 KNZ71633.1 - 3e-19 69.4 0.1 5.4e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KNZ71633.1 - 1.1e-18 66.5 4.8 1.1e-17 63.4 2.7 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KNZ71633.1 - 1.6e-16 59.9 0.1 1.4e-15 56.9 0.0 2.3 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KNZ71633.1 - 1.7e-13 49.9 2.8 1.2e-07 31.2 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KNZ71633.1 - 8.5e-11 41.6 0.0 1.7e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD PF00529.15 KNZ71633.1 - 2.6e-08 33.5 3.2 0.00051 19.4 0.1 2.6 2 1 1 3 3 3 2 HlyD family secretion protein ATP-grasp PF02222.17 KNZ71633.1 - 1.3e-07 31.0 0.0 2.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 KNZ71633.1 - 2.3e-06 27.9 0.7 0.035 14.4 0.0 2.9 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 KNZ71633.1 - 2.3e-05 24.3 0.0 8e-05 22.5 0.0 2.0 2 0 0 2 2 1 1 ATP-grasp domain GCV_H PF01597.14 KNZ71633.1 - 7.1e-05 22.4 1.4 0.0012 18.5 0.3 3.1 3 1 0 3 3 3 1 Glycine cleavage H-protein RimK PF08443.6 KNZ71633.1 - 0.00076 19.0 0.0 0.0024 17.3 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain NQRA PF05896.6 KNZ71633.1 - 0.0019 17.4 0.2 0.0049 16.1 0.1 1.6 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_2 PF12700.2 KNZ71633.1 - 0.0053 15.9 0.5 0.22 10.6 0.0 2.2 1 1 1 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 KNZ71633.1 - 0.0095 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.1 KNZ71633.1 - 0.011 15.4 1.0 0.037 13.7 0.6 1.8 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.4 KNZ71633.1 - 0.036 13.7 0.2 0.2 11.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) PNPase PF03726.9 KNZ71633.1 - 0.11 12.8 0.2 0.32 11.3 0.1 1.8 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain UAA PF08449.6 KNZ71634.1 - 1.2e-14 54.0 16.3 1.5e-14 53.6 11.3 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KNZ71634.1 - 8.9e-11 41.6 5.1 8.9e-11 41.6 3.5 3.0 1 1 2 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 KNZ71634.1 - 0.0062 16.5 6.0 0.0062 16.5 4.2 2.2 2 0 0 2 2 2 1 EamA-like transporter family UCR_6-4kD PF08997.5 KNZ71634.1 - 0.11 12.2 0.1 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein PQ-loop PF04193.9 KNZ71635.1 - 1.1e-16 60.1 4.1 4.6e-13 48.5 1.2 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF1771 PF08590.5 KNZ71636.1 - 8.3e-13 48.1 7.9 1.5e-12 47.3 5.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.19 KNZ71636.1 - 9.1e-08 31.6 7.8 0.0022 17.6 0.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.16 KNZ71636.1 - 9.5e-05 22.5 0.1 0.0003 20.9 0.1 1.9 1 0 0 1 1 1 1 Smr domain HBS1_N PF08938.5 KNZ71636.1 - 0.0023 18.0 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 HBS1 N-terminus zf-C3H1 PF10650.4 KNZ71636.1 - 0.31 10.5 3.3 5.7 6.5 0.4 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain zf-CCCH_2 PF14608.1 KNZ71636.1 - 1.3 9.1 6.6 2.6 8.2 0.5 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type AAA_12 PF13087.1 KNZ71638.1 - 9.8e-35 119.7 0.1 2.8e-34 118.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA PF00004.24 KNZ71638.1 - 3.2e-32 111.5 3.0 6.6e-09 36.0 0.0 7.1 6 1 1 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 KNZ71638.1 - 8.5e-25 87.6 11.8 4.6e-19 68.9 0.0 6.3 5 2 0 5 5 5 2 AAA domain AAA_19 PF13245.1 KNZ71638.1 - 4.6e-18 64.7 5.3 1.2e-05 24.9 0.0 5.6 6 0 0 6 6 5 4 Part of AAA domain AAA_17 PF13207.1 KNZ71638.1 - 3.9e-13 50.2 7.3 0.013 16.2 0.0 6.0 6 0 0 6 6 4 4 AAA domain AAA_5 PF07728.9 KNZ71638.1 - 2.8e-12 46.5 0.5 0.13 12.0 0.0 5.0 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KNZ71638.1 - 9.3e-11 41.2 0.3 0.096 11.8 0.0 4.7 4 0 0 4 4 4 4 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KNZ71638.1 - 9.8e-11 41.3 1.7 0.31 10.4 0.0 5.0 5 0 0 5 5 4 4 IstB-like ATP binding protein AAA_22 PF13401.1 KNZ71638.1 - 1e-10 41.8 6.5 0.17 12.0 0.1 7.4 5 2 0 5 5 5 3 AAA domain AAA_30 PF13604.1 KNZ71638.1 - 4e-10 39.6 8.3 0.012 15.1 0.0 6.4 6 1 0 6 6 5 3 AAA domain AAA_18 PF13238.1 KNZ71638.1 - 3e-09 37.2 6.8 0.18 12.1 0.0 5.9 5 0 0 5 5 4 3 AAA domain AAA_16 PF13191.1 KNZ71638.1 - 6.3e-09 36.0 10.5 0.0053 16.7 0.0 5.6 6 0 0 6 6 4 2 AAA ATPase domain AAA_33 PF13671.1 KNZ71638.1 - 1.6e-07 31.2 3.8 0.59 10.0 0.0 5.0 4 0 0 4 4 4 3 AAA domain RuvB_N PF05496.7 KNZ71638.1 - 5.4e-07 28.9 0.3 0.3 10.0 0.0 4.9 5 0 0 5 5 5 1 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 KNZ71638.1 - 5.9e-07 28.7 3.6 0.0081 15.1 0.0 5.7 5 2 0 5 5 5 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 KNZ71638.1 - 2.6e-06 27.5 0.4 6.3 7.0 0.0 5.3 5 0 0 5 5 5 0 RNA helicase AAA_25 PF13481.1 KNZ71638.1 - 7.5e-06 25.4 3.9 1.2 8.4 0.0 5.4 5 0 0 5 5 5 1 AAA domain Viral_helicase1 PF01443.13 KNZ71638.1 - 8.9e-06 25.3 1.9 0.039 13.4 0.0 5.4 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 KNZ71638.1 - 2e-05 24.1 0.3 8.6 5.8 0.0 5.0 5 0 0 5 5 5 0 Sigma-54 interaction domain AAA_24 PF13479.1 KNZ71638.1 - 5.2e-05 22.9 7.7 0.34 10.4 0.0 4.6 4 0 0 4 4 4 2 AAA domain PhoH PF02562.11 KNZ71638.1 - 6.2e-05 22.3 0.8 5 6.2 0.0 4.6 4 0 0 4 4 4 1 PhoH-like protein AAA_28 PF13521.1 KNZ71638.1 - 0.0002 21.3 18.5 0.15 12.0 0.1 5.8 5 1 0 5 5 4 3 AAA domain Torsin PF06309.6 KNZ71638.1 - 0.00029 20.7 0.1 1.8 8.4 0.0 4.1 4 0 0 4 4 4 1 Torsin AAA_14 PF13173.1 KNZ71638.1 - 0.0026 17.6 0.1 11 5.9 0.0 4.7 4 0 0 4 4 3 0 AAA domain AAA_29 PF13555.1 KNZ71638.1 - 0.0061 16.0 2.6 16 5.1 0.0 4.6 4 0 0 4 4 4 0 P-loop containing region of AAA domain NACHT PF05729.7 KNZ71638.1 - 0.02 14.5 5.7 18 4.9 0.2 5.5 5 1 0 5 5 4 0 NACHT domain NTPase_1 PF03266.10 KNZ71638.1 - 0.085 12.5 4.2 14 5.3 0.0 4.4 5 0 0 5 5 4 0 NTPase KaiC PF06745.8 KNZ71638.1 - 0.091 11.8 5.6 13 4.8 0.0 4.7 5 0 0 5 5 5 0 KaiC RVP_2 PF08284.6 KNZ71639.1 - 0.015 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease CNTF PF01110.12 KNZ71641.1 - 0.074 12.3 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor Asp_protease_2 PF13650.1 KNZ71646.1 - 0.00043 20.7 0.0 0.0011 19.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease NSP10 PF09401.5 KNZ71646.1 - 0.04 13.6 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA synthesis protein NSP10 Asp_protease PF09668.5 KNZ71646.1 - 0.081 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.21 KNZ71647.1 - 0.033 14.3 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.12 KNZ71648.1 - 0.021 14.9 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein DUF2496 PF10689.4 KNZ71649.1 - 0.4 10.2 3.6 1.7 8.3 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2496) Spc42p PF11544.3 KNZ71649.1 - 1.8 8.5 16.9 1.5 8.8 0.4 3.9 2 2 0 3 3 3 0 Spindle pole body component Spc42p Allantoicase PF03561.10 KNZ71650.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Allantoicase repeat APH PF01636.18 KNZ71651.1 - 4.5e-07 29.8 0.6 9e-07 28.8 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ71651.1 - 0.0015 18.1 0.3 0.0038 16.8 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 KNZ71651.1 - 0.0025 17.0 0.0 0.011 14.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain SAGA-Tad1 PF12767.2 KNZ71652.1 - 0.0039 16.8 7.7 0.0054 16.4 5.3 1.3 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Draxin PF15550.1 KNZ71652.1 - 0.29 10.7 4.5 0.35 10.4 3.1 1.1 1 0 0 1 1 1 0 Draxin MFS_1 PF07690.11 KNZ71653.1 - 4.7e-35 120.9 60.6 3.3e-33 114.8 42.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily PalH PF08733.5 KNZ71653.1 - 0.29 9.9 4.7 0.46 9.2 3.3 1.2 1 0 0 1 1 1 0 PalH/RIM21 Phage_holin_2 PF04550.7 KNZ71653.1 - 7.6 6.7 8.0 0.55 10.3 0.9 2.5 3 0 0 3 3 3 0 Phage holin family 2 ketoacyl-synt PF00109.21 KNZ71654.1 - 2.4e-17 63.2 0.0 6.4e-17 61.8 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Glyco_hydro_35 PF01301.14 KNZ71656.1 - 2.8e-69 233.9 0.0 4.1e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 KNZ71656.1 - 1.7e-47 160.2 4.7 4.1e-26 91.4 0.3 3.0 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 KNZ71656.1 - 5.6e-35 120.3 1.5 1e-34 119.5 1.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 KNZ71656.1 - 3.5e-19 67.9 0.4 8.9e-19 66.6 0.0 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Amidohydro_2 PF04909.9 KNZ71656.1 - 0.006 16.1 0.1 0.025 14.1 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase Glyco_hydro_42 PF02449.10 KNZ71656.1 - 0.11 11.5 0.1 2.1 7.4 0.0 2.2 1 1 0 1 1 1 0 Beta-galactosidase COX4 PF02936.9 KNZ71657.1 - 5.5e-22 78.0 0.0 1e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV TIP41 PF04176.8 KNZ71658.1 - 0.14 11.3 0.8 1.5 8.0 0.2 2.1 2 0 0 2 2 2 0 TIP41-like family Cation_efflux PF01545.16 KNZ71667.1 - 2.6e-79 266.2 10.2 5.9e-79 265.1 7.1 1.5 1 1 0 1 1 1 1 Cation efflux family Alginate_lyase PF05426.7 KNZ71669.1 - 3.6e-39 134.7 3.8 1.1e-38 133.2 2.6 1.7 1 1 0 1 1 1 1 Alginate lyase Globin PF00042.17 KNZ71670.1 - 0.083 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Globin DUF2930 PF11152.3 KNZ71670.1 - 0.092 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2930) Pkinase PF00069.20 KNZ71671.1 - 4.6e-05 22.7 0.0 4.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ71671.1 - 0.006 15.6 0.0 0.006 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase XH PF03469.9 KNZ71671.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 XH domain Pkinase PF00069.20 KNZ71673.1 - 4.6e-05 22.7 0.0 4.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ71673.1 - 0.006 15.6 0.0 0.006 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase XH PF03469.9 KNZ71673.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 XH domain RVP_2 PF08284.6 KNZ71674.1 - 0.052 13.4 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RNA_Me_trans PF04252.8 KNZ71677.1 - 8.7e-37 126.4 0.0 1.5e-36 125.6 0.0 1.4 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Annexin PF00191.15 KNZ71678.1 - 2e-49 165.3 0.2 1.4e-15 56.9 0.0 4.3 4 0 0 4 4 4 4 Annexin F-box-like PF12937.2 KNZ71679.1 - 2.6e-06 27.0 2.1 3.8e-06 26.5 0.5 2.2 2 0 0 2 2 2 1 F-box-like Cellulase PF00150.13 KNZ71680.1 - 6.1e-12 45.3 0.0 6.2e-07 28.8 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) COesterase PF00135.23 KNZ71681.1 - 2.4e-96 323.5 0.0 2.7e-96 323.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ71681.1 - 6e-09 35.7 0.0 1.6e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KNZ71681.1 - 0.059 12.5 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S10 PF00450.17 KNZ71683.1 - 1.2e-84 284.9 0.1 1.4e-84 284.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase 2OG-FeII_Oxy PF03171.15 KNZ71685.1 - 1.1e-10 41.7 0.0 1.9e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KNZ71685.1 - 3.8e-08 33.8 0.0 1.3e-07 32.1 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal ABC_membrane PF00664.18 KNZ71686.1 - 6.1e-47 160.3 38.1 4.8e-26 91.7 10.5 3.4 3 1 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KNZ71686.1 - 6.6e-41 139.8 0.0 1.4e-25 90.2 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 KNZ71686.1 - 1.9e-10 40.4 2.3 0.00012 21.6 1.2 2.9 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 KNZ71686.1 - 3.7e-09 36.1 5.5 0.11 11.6 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KNZ71686.1 - 3.4e-08 33.7 4.3 0.061 13.2 0.1 4.2 2 2 2 4 4 4 2 AAA domain AAA PF00004.24 KNZ71686.1 - 1.4e-06 28.5 0.0 0.1 12.8 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNZ71686.1 - 1.7e-06 28.1 2.2 0.0078 16.2 0.4 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KNZ71686.1 - 9.9e-06 25.0 0.1 0.18 11.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KNZ71686.1 - 3.6e-05 23.8 2.9 0.65 10.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KNZ71686.1 - 6e-05 23.8 0.0 0.095 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KNZ71686.1 - 8.5e-05 22.1 4.3 0.77 9.1 0.0 4.2 4 0 0 4 4 4 1 AAA-like domain AAA_23 PF13476.1 KNZ71686.1 - 0.00011 22.6 5.9 0.00095 19.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 KNZ71686.1 - 0.00012 21.8 0.5 0.057 13.1 0.1 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KNZ71686.1 - 0.00013 20.9 1.2 0.15 10.9 0.0 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein DUF87 PF01935.12 KNZ71686.1 - 0.00028 20.7 0.8 0.0043 16.9 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 Arch_ATPase PF01637.13 KNZ71686.1 - 0.0003 20.5 0.0 0.33 10.6 0.0 2.4 2 0 0 2 2 2 2 Archaeal ATPase MMR_HSR1 PF01926.18 KNZ71686.1 - 0.00037 20.4 0.1 0.53 10.2 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.12 KNZ71686.1 - 0.00041 19.8 1.8 2.5 7.4 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein DEAD PF00270.24 KNZ71686.1 - 0.00058 19.3 0.1 0.022 14.2 0.1 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.1 KNZ71686.1 - 0.00075 19.8 0.0 0.61 10.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 KNZ71686.1 - 0.00079 19.9 0.0 0.81 10.1 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein Adeno_IVa2 PF02456.10 KNZ71686.1 - 0.0013 17.4 0.1 0.0066 15.1 0.0 1.9 2 0 0 2 2 2 1 Adenovirus IVa2 protein DUF258 PF03193.11 KNZ71686.1 - 0.0017 17.6 0.0 0.92 8.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KNZ71686.1 - 0.0017 18.2 0.0 3 7.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KNZ71686.1 - 0.0017 18.0 1.1 3.2 7.4 0.0 3.8 3 1 1 4 4 4 1 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 KNZ71686.1 - 0.0021 17.6 0.1 2.2 7.7 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 KNZ71686.1 - 0.003 17.2 2.7 5.3 6.6 0.0 3.4 3 0 0 3 3 3 0 NACHT domain FtsK_SpoIIIE PF01580.13 KNZ71686.1 - 0.013 15.0 0.7 0.46 9.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.10 KNZ71686.1 - 0.015 15.1 0.2 7.3 6.3 0.1 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KNZ71686.1 - 0.023 14.8 0.0 8 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 KNZ71686.1 - 0.036 13.1 0.0 6.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.7 KNZ71686.1 - 0.049 12.9 0.5 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_14 PF13173.1 KNZ71686.1 - 0.054 13.4 0.0 7 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 KNZ71686.1 - 0.071 12.5 0.9 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 KNZ71686.1 - 0.087 12.6 3.3 6.5 6.5 0.0 2.9 3 0 0 3 3 2 0 Dynamin family AAA_11 PF13086.1 KNZ71686.1 - 0.21 11.1 0.0 0.44 10.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KNZ71686.1 - 0.3 10.5 0.5 25 4.2 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 KNZ71686.1 - 1.3 8.4 4.4 39 3.6 0.1 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.4 KNZ71686.1 - 1.7 7.5 3.7 1.3 7.9 0.2 2.4 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Glyco_hydro_1 PF00232.13 KNZ71687.1 - 4.1e-144 480.1 0.9 1.3e-115 386.2 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 1 adh_short PF00106.20 KNZ71688.1 - 4.4e-26 91.7 2.5 2e-25 89.6 1.7 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ71688.1 - 4.6e-20 72.4 0.4 2.9e-13 50.1 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ71688.1 - 4e-10 39.6 0.2 6.2e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KNZ71688.1 - 0.0092 15.4 0.1 0.75 9.1 0.0 2.2 1 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KNZ71688.1 - 0.035 13.9 0.2 0.1 12.4 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TRI5 PF06330.6 KNZ71689.1 - 8.3e-24 83.9 0.7 1e-23 83.6 0.5 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) F-box-like PF12937.2 KNZ71690.1 - 0.048 13.3 0.1 0.17 11.6 0.1 1.9 1 0 0 1 1 1 0 F-box-like INCENP_N PF12178.3 KNZ71690.1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal TRI5 PF06330.6 KNZ71691.1 - 1.2e-19 70.2 0.0 2.5e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) FHA PF00498.21 KNZ71692.1 - 1.8e-06 27.9 0.0 3.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain UbiA PF01040.13 KNZ71693.1 - 1.9e-29 102.6 22.2 2.4e-29 102.3 15.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Isy1 PF06246.7 KNZ71694.1 - 9.9e-69 231.5 2.7 1.2e-68 231.2 1.9 1.0 1 0 0 1 1 1 1 Isy1-like splicing family UPF0193 PF05250.6 KNZ71694.1 - 0.028 13.9 0.5 1.5 8.3 0.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0193) Secretin PF00263.16 KNZ71694.1 - 0.16 11.3 0.0 0.78 9.0 0.0 1.9 1 1 0 1 1 1 0 Bacterial type II and III secretion system protein N2227 PF07942.7 KNZ71695.1 - 9.2e-87 290.4 0.0 4.4e-58 196.3 0.0 2.1 2 0 0 2 2 2 2 N2227-like protein Methyltransf_23 PF13489.1 KNZ71695.1 - 0.0039 16.9 0.0 0.018 14.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 KNZ71695.1 - 0.1 12.0 0.0 0.24 10.7 0.0 1.6 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Sugar_tr PF00083.19 KNZ71696.1 - 4.5e-110 368.3 29.3 5.4e-110 368.0 20.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ71696.1 - 4.6e-27 94.6 27.2 4.6e-27 94.6 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OTT_1508_deam PF14441.1 KNZ71698.1 - 1.6e-07 31.2 0.1 3e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase COPIIcoated_ERV PF07970.7 KNZ71699.1 - 1.1e-34 119.9 0.4 3.1e-34 118.5 0.3 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KNZ71699.1 - 5.4e-19 67.9 0.0 9.7e-19 67.1 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Peptidase_M36 PF02128.10 KNZ71701.1 - 1.1e-39 136.4 9.8 4.5e-32 111.3 3.1 2.1 1 1 1 2 2 2 2 Fungalysin metallopeptidase (M36) Pkinase PF00069.20 KNZ71702.1 - 6e-09 35.4 0.7 2.6e-08 33.3 0.5 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ71702.1 - 0.00017 20.7 0.3 0.00047 19.3 0.2 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KNZ71702.1 - 0.01 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KNZ71702.1 - 0.016 14.9 2.1 0.33 10.6 0.3 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family rve PF00665.21 KNZ71704.1 - 0.0001 22.3 0.1 0.00074 19.6 0.0 2.1 1 1 1 2 2 2 1 Integrase core domain rve PF00665.21 KNZ71707.1 - 3.9e-05 23.7 0.0 7.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF2286 PF10051.4 KNZ71709.1 - 0.067 12.8 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2286) Sod_Fe_C PF02777.13 KNZ71712.1 - 3.6e-10 39.6 0.3 0.00013 21.7 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain DAD PF02109.11 KNZ71713.1 - 9.6e-47 157.7 1.1 1.1e-46 157.4 0.7 1.0 1 0 0 1 1 1 1 DAD family SSP160 PF06933.6 KNZ71713.1 - 0.093 10.6 0.0 0.11 10.5 0.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1600 PF07667.6 KNZ71713.1 - 0.095 12.8 0.3 0.14 12.2 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1600) DUF1748 PF08520.5 KNZ71714.1 - 7.2e-19 67.2 0.0 7.5e-19 67.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) DUF2838 PF10998.3 KNZ71715.1 - 4.3e-38 129.6 11.4 9.1e-38 128.5 7.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) Fijivirus_P9-2 PF06837.6 KNZ71715.1 - 0.048 12.8 1.7 0.083 12.0 1.2 1.4 1 0 0 1 1 1 0 Fijivirus P9-2 protein Curto_V3 PF07436.6 KNZ71715.1 - 0.087 12.9 0.1 24 5.1 0.0 2.9 2 0 0 2 2 2 0 Curtovirus V3 protein AAA_13 PF13166.1 KNZ71715.1 - 0.13 10.6 0.6 0.19 10.1 0.4 1.1 1 0 0 1 1 1 0 AAA domain Hexokinase_2 PF03727.11 KNZ71716.1 - 3.5e-65 219.5 0.0 5.3e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KNZ71716.1 - 5.3e-63 212.0 0.0 7.2e-63 211.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase UPF0270 PF06794.7 KNZ71716.1 - 0.036 13.8 0.0 0.14 11.9 0.0 2.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) rve PF00665.21 KNZ71718.1 - 0.00052 20.1 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain AAA_22 PF13401.1 KNZ71719.1 - 0.063 13.4 0.0 12 6.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 KNZ71719.1 - 0.099 12.6 0.0 2.2 8.2 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain WD40 PF00400.27 KNZ71721.1 - 3.3e-09 36.2 0.0 0.0024 17.6 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat PQQ_2 PF13360.1 KNZ71721.1 - 7.2e-05 22.3 1.7 0.004 16.6 0.0 3.2 2 1 1 3 3 3 2 PQQ-like domain BBS1 PF14779.1 KNZ71721.1 - 0.00029 19.9 0.7 0.96 8.3 0.0 3.8 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 1 PQQ_3 PF13570.1 KNZ71721.1 - 0.00059 20.0 0.3 3.1 8.1 0.0 4.6 5 0 0 5 5 5 1 PQQ-like domain BBS2_Mid PF14783.1 KNZ71721.1 - 0.00088 19.0 0.3 5.7 6.7 0.0 3.8 2 1 2 4 4 4 3 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.16 KNZ71721.1 - 0.022 14.2 0.1 2 8.0 0.0 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat gag-asp_proteas PF13975.1 KNZ71724.1 - 0.00028 20.6 0.0 0.00035 20.3 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KNZ71724.1 - 0.00035 20.5 0.0 0.0004 20.3 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KNZ71724.1 - 0.0028 18.1 0.0 0.0034 17.8 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease DUF2205 PF10224.4 KNZ71725.1 - 0.0058 16.1 2.2 0.0058 16.1 1.5 2.7 2 0 0 2 2 2 1 Predicted coiled-coil protein (DUF2205) Chibby PF14645.1 KNZ71725.1 - 0.17 11.7 3.6 0.15 11.9 0.8 2.1 2 0 0 2 2 2 0 Chibby family DivIC PF04977.10 KNZ71725.1 - 0.28 10.6 9.1 0.072 12.5 1.1 2.4 2 0 0 2 2 2 0 Septum formation initiator Mt_ATP-synt_D PF05873.7 KNZ71725.1 - 0.93 9.1 8.6 0.88 9.1 2.8 2.9 2 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF972 PF06156.8 KNZ71725.1 - 1.9 8.8 9.6 0.35 11.2 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 KNZ71725.1 - 3.1 7.3 7.9 2.7 7.5 1.9 2.2 2 0 0 2 2 2 0 IncA protein bZIP_1 PF00170.16 KNZ71725.1 - 8.4 6.4 7.5 0.7 9.8 1.5 2.0 2 0 0 2 2 2 0 bZIP transcription factor RVP_2 PF08284.6 KNZ71726.1 - 0.11 12.4 0.1 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease His_Phos_1 PF00300.17 KNZ71727.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) P53_TAD PF08563.6 KNZ71730.1 - 0.022 13.8 0.0 0.049 12.7 0.0 1.6 1 0 0 1 1 1 0 P53 transactivation motif NACHT PF05729.7 KNZ71731.1 - 0.00077 19.1 0.0 0.0015 18.1 0.0 1.5 1 1 0 1 1 1 1 NACHT domain Creatininase PF02633.9 KNZ71731.1 - 0.12 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Creatinine amidohydrolase Pkinase PF00069.20 KNZ71732.1 - 1.8e-36 125.6 0.0 6.1e-36 123.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ71732.1 - 6.2e-16 58.2 0.0 9.8e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ71732.1 - 0.00051 19.8 0.0 0.0023 17.7 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KNZ71732.1 - 0.0025 16.7 0.0 0.0038 16.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.15 KNZ71732.1 - 0.0032 17.0 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KNZ71732.1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like EF-hand_1 PF00036.27 KNZ71733.1 - 3.3e-26 88.5 16.5 2.9e-09 35.5 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KNZ71733.1 - 6.9e-24 83.7 14.2 5.3e-12 45.7 1.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KNZ71733.1 - 1e-23 81.0 13.9 1.7e-08 33.6 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KNZ71733.1 - 2.5e-16 59.0 17.7 7e-08 31.9 1.5 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KNZ71733.1 - 2.3e-13 48.7 10.0 0.00081 18.6 0.0 3.8 4 0 0 4 4 3 3 EF hand EF-hand_9 PF14658.1 KNZ71733.1 - 5.3e-12 45.4 1.0 1.2e-05 25.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KNZ71733.1 - 1.9e-08 34.0 6.7 0.00045 19.9 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand DUF1636 PF07845.6 KNZ71733.1 - 0.0014 18.8 0.0 1.2 9.4 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1636) Caleosin PF05042.8 KNZ71733.1 - 0.0057 16.2 0.1 0.12 11.9 0.0 2.3 2 1 0 2 2 2 1 Caleosin related protein DUF4601 PF15373.1 KNZ71733.1 - 0.012 14.4 0.2 0.021 13.6 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4601) DUF3164 PF11363.3 KNZ71733.1 - 0.021 14.1 0.1 1.2 8.5 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3164) SPARC_Ca_bdg PF10591.4 KNZ71733.1 - 0.11 12.4 3.2 2.5 8.1 0.1 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region YolD PF08863.5 KNZ71733.1 - 0.13 12.1 0.5 2 8.3 0.1 2.3 2 1 0 2 2 2 0 YolD-like protein MerR-DNA-bind PF09278.6 KNZ71733.1 - 0.19 12.1 2.1 20 5.6 0.1 3.2 2 1 1 3 3 3 0 MerR, DNA binding MgtE_N PF03448.12 KNZ71733.1 - 1.6 9.0 6.1 0.88 9.9 1.0 2.5 3 0 0 3 3 3 0 MgtE intracellular N domain zf-C2H2 PF00096.21 KNZ71734.1 - 1.3e-10 40.9 6.9 0.00022 21.3 0.2 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ71734.1 - 1.7e-06 27.9 4.1 0.0012 19.0 0.6 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KNZ71734.1 - 9.6e-05 22.4 3.6 9.6e-05 22.4 2.5 4.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KNZ71734.1 - 0.0042 16.9 0.1 0.0042 16.9 0.1 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KNZ71735.1 - 5.1e-08 32.7 17.5 0.00035 20.7 3.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ71735.1 - 3.6e-05 23.8 15.6 0.01 16.0 2.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KNZ71735.1 - 0.0015 18.7 7.9 0.0015 18.7 5.5 3.3 3 0 0 3 3 3 1 Zinc-finger double domain FANCL_C PF11793.3 KNZ71735.1 - 0.046 13.6 2.1 0.086 12.8 1.4 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C2H2_6 PF13912.1 KNZ71735.1 - 0.061 13.2 0.4 0.061 13.2 0.2 2.2 3 0 0 3 3 3 0 C2H2-type zinc finger DUF950 PF06106.6 KNZ71737.1 - 0.0036 17.3 0.1 0.0041 17.1 0.0 1.0 1 0 0 1 1 1 1 Staphylococcus protein of unknown function (DUF950) PAP_assoc PF03828.14 KNZ71738.1 - 2.9e-05 23.9 0.1 6.6e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KNZ71738.1 - 0.00015 22.0 0.0 0.00034 20.8 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Glucan_synthase PF02364.10 KNZ71742.1 - 0 1364.1 0.0 0 1363.5 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KNZ71742.1 - 4.7e-39 132.9 0.6 1.2e-38 131.6 0.0 2.0 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 NinE PF05322.6 KNZ71742.1 - 0.094 12.4 0.1 0.8 9.4 0.0 2.5 2 0 0 2 2 2 0 NINE Protein SpoIIE PF07228.7 KNZ71744.1 - 1.5e-13 50.8 0.0 2.2e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KNZ71744.1 - 4.5e-06 26.2 0.0 1.1e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KNZ71744.1 - 0.018 14.4 0.4 2.2 7.6 0.0 2.7 2 1 0 3 3 3 0 Protein phosphatase 2C DNA_pol3_gamma3 PF12169.3 KNZ71744.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III Peptidase_M49 PF03571.10 KNZ71745.1 - 8.1e-188 624.9 0.0 9.5e-188 624.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 FAD_binding_3 PF01494.14 KNZ71746.1 - 5.1e-36 124.4 0.0 7.9e-22 77.7 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KNZ71746.1 - 3.2e-06 26.2 0.0 0.039 12.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KNZ71746.1 - 1.9e-05 24.8 0.0 4.6e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KNZ71746.1 - 0.00027 19.5 0.0 0.31 9.4 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 KNZ71746.1 - 0.00066 19.6 0.1 0.0027 17.6 0.1 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ71746.1 - 0.0044 16.9 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KNZ71746.1 - 0.0076 16.0 0.0 0.46 10.2 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KNZ71746.1 - 0.0085 16.4 0.2 5.5 7.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KNZ71746.1 - 0.021 14.7 0.1 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.19 KNZ71746.1 - 0.027 13.3 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 KNZ71746.1 - 0.029 13.4 0.5 0.29 10.1 0.5 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.5 KNZ71746.1 - 0.042 12.6 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Lycopene_cycl PF05834.7 KNZ71746.1 - 0.052 12.4 0.1 0.21 10.4 0.0 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 KNZ71746.1 - 0.09 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TPR_12 PF13424.1 KNZ71747.1 - 1.4e-09 37.7 13.6 0.022 14.6 0.1 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ71747.1 - 1.3e-05 24.7 2.5 0.28 10.8 0.3 3.6 3 1 0 3 3 3 2 TPR repeat TPR_10 PF13374.1 KNZ71747.1 - 2.7e-05 23.9 0.6 0.00015 21.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ71747.1 - 0.0012 18.4 0.4 5.6 6.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF1938 PF09153.5 KNZ71747.1 - 0.003 17.3 0.0 0.028 14.2 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1938) TPR_2 PF07719.12 KNZ71747.1 - 0.019 14.8 8.8 1.3 9.1 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ71747.1 - 0.062 12.9 4.5 8.9 6.1 0.5 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ71747.1 - 8.7 7.1 18.9 0.85 10.3 0.2 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat Cellulase PF00150.13 KNZ71748.1 - 6.3e-15 55.1 0.5 2e-14 53.4 0.2 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.1 KNZ71748.1 - 9.9e-05 21.8 0.2 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.10 KNZ71748.1 - 0.00016 20.9 0.5 0.0045 16.1 0.2 2.7 2 1 0 2 2 2 1 Beta-galactosidase Cellulase-like PF12876.2 KNZ71748.1 - 0.028 14.8 0.0 0.075 13.4 0.0 1.7 1 0 0 1 1 1 0 Sugar-binding cellulase-like Glyco_hydro_1 PF00232.13 KNZ71748.1 - 0.055 11.6 0.0 0.17 10.0 0.1 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 1 NP1-WLL PF11733.3 KNZ71748.1 - 0.21 11.8 2.5 0.46 10.7 1.8 1.5 1 0 0 1 1 1 0 Non-capsid protein NP1 DUF1227 PF06777.6 KNZ71749.1 - 2.7e-56 189.3 0.1 4.9e-56 188.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KNZ71749.1 - 3.1e-48 163.4 0.0 5.4e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 KNZ71749.1 - 9.9e-44 149.2 0.0 2e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 KNZ71749.1 - 0.00092 18.7 0.1 0.4 10.1 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.18 KNZ71749.1 - 0.004 15.9 0.0 0.52 9.0 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.10 KNZ71749.1 - 0.0054 16.5 0.2 0.069 12.9 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit YtxC PF08812.6 KNZ71749.1 - 0.1 12.0 0.2 0.42 10.0 0.1 2.1 2 0 0 2 2 2 0 YtxC-like family AAA_22 PF13401.1 KNZ71749.1 - 0.1 12.7 0.1 8.5 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Peptidase_M41 PF01434.13 KNZ71750.1 - 3.4e-67 226.0 0.1 5.3e-67 225.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KNZ71750.1 - 1.6e-43 148.0 0.0 7.7e-43 145.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KNZ71750.1 - 6.1e-06 26.0 0.4 7e-05 22.5 0.1 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KNZ71750.1 - 1e-05 25.5 2.0 0.0024 17.8 0.1 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 KNZ71750.1 - 1.6e-05 25.7 0.0 5.3e-05 24.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KNZ71750.1 - 3.8e-05 23.3 0.2 0.00016 21.3 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 KNZ71750.1 - 0.00012 20.9 0.0 0.00027 19.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KNZ71750.1 - 0.00017 20.7 0.0 0.00039 19.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KNZ71750.1 - 0.00021 21.4 0.8 0.011 15.9 0.2 2.9 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KNZ71750.1 - 0.0008 18.8 0.1 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 KNZ71750.1 - 0.01 15.8 1.1 0.015 15.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 KNZ71750.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KNZ71750.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KNZ71750.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KNZ71750.1 - 0.014 14.5 0.3 0.031 13.4 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KNZ71750.1 - 0.017 14.1 0.4 0.038 13.0 0.2 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 KNZ71750.1 - 0.025 13.9 5.6 0.058 12.7 0.5 2.7 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.21 KNZ71750.1 - 0.032 13.7 0.3 0.26 10.7 0.0 2.4 2 1 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.8 KNZ71750.1 - 0.038 12.9 0.0 0.085 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_2 PF07724.9 KNZ71750.1 - 0.042 13.7 0.0 0.16 11.8 0.0 2.0 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.7 KNZ71750.1 - 0.043 13.4 0.1 0.32 10.6 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Beta_protein PF14350.1 KNZ71750.1 - 0.06 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Beta protein KaiC PF06745.8 KNZ71750.1 - 0.062 12.4 0.3 0.41 9.7 0.0 2.2 2 0 0 2 2 2 0 KaiC Sigma54_activ_2 PF14532.1 KNZ71750.1 - 0.085 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain PGAP1 PF07819.8 KNZ71750.1 - 0.088 12.3 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein DUF2075 PF09848.4 KNZ71750.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Glyco_transf_54 PF04666.8 KNZ71750.1 - 0.14 10.8 0.0 0.24 10.0 0.0 1.3 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region RNA_helicase PF00910.17 KNZ71750.1 - 0.15 12.2 0.1 0.85 9.8 0.0 2.3 2 1 0 2 2 1 0 RNA helicase Parvo_NS1 PF01057.12 KNZ71750.1 - 0.2 10.4 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 GCIP PF13324.1 KNZ71751.1 - 6.6e-16 58.3 0.1 8.9e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting DUF851 PF05867.6 KNZ71752.1 - 0.027 13.7 0.2 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF851) DUF2762 PF10960.3 KNZ71752.1 - 0.72 9.5 3.4 1.2 8.9 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) FBPase PF00316.15 KNZ71753.1 - 1.2e-120 402.2 0.0 1.3e-120 402.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 KNZ71753.1 - 3.2e-05 23.3 0.0 5.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family zf-H2C2_2 PF13465.1 KNZ71754.1 - 1.3e-25 88.4 21.0 2.1e-07 30.8 0.1 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KNZ71754.1 - 1.3e-20 72.4 27.8 2.8e-05 24.1 2.3 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ71754.1 - 3e-15 55.3 24.5 0.00037 20.6 1.7 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KNZ71754.1 - 2.9e-07 30.4 4.8 0.29 11.3 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KNZ71754.1 - 1.3e-05 25.2 5.0 0.23 11.7 0.2 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KNZ71754.1 - 2.2e-05 24.1 6.1 0.19 11.6 0.0 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger TAP42 PF04177.7 KNZ71754.1 - 0.077 11.9 1.4 0.48 9.3 0.3 2.2 2 0 0 2 2 2 0 TAP42-like family zf-TRAF PF02176.13 KNZ71754.1 - 0.4 11.0 15.1 0.15 12.4 2.4 3.1 1 1 2 3 3 3 0 TRAF-type zinc finger zf-CGNR PF11706.3 KNZ71754.1 - 2 7.9 11.5 28 4.3 0.4 4.3 4 0 0 4 4 4 0 CGNR zinc finger Pmp3 PF01679.12 KNZ71755.1 - 1.9e-16 59.4 3.6 2.4e-16 59.1 2.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PNGaseA PF12222.3 KNZ71756.1 - 7.5e-73 245.8 3.3 1.1e-72 245.2 2.3 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A FTHFS PF01268.14 KNZ71757.1 - 2.3e-255 847.8 0.1 3.1e-255 847.4 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KNZ71757.1 - 7.2e-66 220.2 0.1 1.7e-65 219.0 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KNZ71757.1 - 7.3e-33 113.0 0.1 1.5e-32 112.0 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GrpE PF01025.14 KNZ71758.1 - 1.9e-43 147.9 0.6 2.5e-43 147.5 0.4 1.2 1 0 0 1 1 1 1 GrpE INTS2 PF14750.1 KNZ71758.1 - 0.15 9.5 0.0 0.2 9.1 0.0 1.1 1 0 0 1 1 1 0 Integrator complex subunit 2 tRNA-synt_2d PF01409.15 KNZ71759.1 - 2.9e-27 95.4 0.1 4.4e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KNZ71759.1 - 3.8e-23 81.4 0.0 7.4e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DUF3552 PF12072.3 KNZ71760.1 - 0.004 16.4 6.1 0.013 14.7 1.6 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3552) GAGA_bind PF06217.7 KNZ71760.1 - 0.027 14.4 0.0 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family DUF1090 PF06476.7 KNZ71760.1 - 1.1 8.8 4.5 14 5.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) FliD_N PF02465.13 KNZ71761.1 - 2.8 8.3 8.8 2.8 8.3 0.4 2.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Porin_3 PF01459.17 KNZ71762.1 - 3.3e-79 266.0 5.9 3.8e-79 265.8 4.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Glyco_transf_15 PF01793.11 KNZ71763.1 - 8e-136 452.3 11.1 9.5e-136 452.0 7.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.11 KNZ71764.1 - 1.8e-134 447.8 7.9 2.3e-134 447.5 5.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PI3_PI4_kinase PF00454.22 KNZ71765.1 - 1.4e-31 109.7 0.0 2.9e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 KNZ71765.1 - 0.0016 18.1 0.0 0.38 10.5 0.0 3.6 3 0 0 3 3 3 1 Yeast phosphatidylinositol-4-OH kinase Pik1 OST3_OST6 PF04756.8 KNZ71766.1 - 8.7e-16 57.8 1.2 1.3e-15 57.3 0.9 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 KNZ71766.1 - 0.00024 20.7 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin 7TMR-DISM_7TM PF07695.6 KNZ71766.1 - 0.3 10.7 8.2 1.5 8.4 5.7 2.0 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF998 PF06197.8 KNZ71766.1 - 0.3 10.3 6.5 0.047 13.0 1.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Sec16_C PF12931.2 KNZ71767.1 - 2.5e-69 234.1 0.0 3.4e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KNZ71767.1 - 1e-27 96.4 0.0 4.2e-27 94.4 0.0 2.2 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region PUF PF00806.14 KNZ71768.1 - 2.2e-61 199.9 7.5 6.2e-09 34.8 0.0 9.8 9 1 0 9 9 9 8 Pumilio-family RNA binding repeat Utp13 PF08625.6 KNZ71768.1 - 0.17 11.5 0.0 0.85 9.2 0.0 2.2 1 1 0 2 2 2 0 Utp13 specific WD40 associated domain Kinesin PF00225.18 KNZ71769.1 - 8.3e-113 376.4 0.1 8.3e-113 376.4 0.1 2.0 2 0 0 2 2 2 1 Kinesin motor domain DUF3580 PF12117.3 KNZ71769.1 - 0.01 15.8 0.3 0.034 14.1 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) Elf1 PF05129.8 KNZ71770.1 - 3.2e-28 97.2 0.3 3.8e-28 97.0 0.2 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.7 KNZ71770.1 - 0.013 15.6 0.5 0.018 15.1 0.3 1.2 1 0 0 1 1 1 0 CHY zinc finger Cytochrome_C554 PF13435.1 KNZ71770.1 - 0.1 12.6 0.7 0.2 11.7 0.5 1.6 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Kinesin PF00225.18 KNZ71771.1 - 2.1e-108 361.9 0.0 4.1e-108 361.0 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 KNZ71771.1 - 0.00085 19.4 0.2 0.00085 19.4 0.1 3.7 4 1 1 5 5 5 1 Kinesin-associated microtubule-binding Vps55 PF04133.9 KNZ71772.1 - 8.5e-42 141.7 3.5 9.4e-42 141.5 2.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 TRAPPC9-Trs120 PF08626.6 KNZ71773.1 - 7.9e-108 361.3 0.0 4e-84 282.8 0.0 2.1 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.1 KNZ71773.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat DPM2 PF07297.7 KNZ71774.1 - 3.7e-30 104.0 0.5 4.2e-30 103.8 0.4 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 KNZ71774.1 - 3.3e-05 23.5 0.4 3.4e-05 23.4 0.3 1.1 1 0 0 1 1 1 1 PIG-P Peptidase_M28 PF04389.12 KNZ71774.1 - 0.067 12.9 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 DUF1469 PF07332.6 KNZ71774.1 - 0.51 10.0 3.1 0.88 9.3 2.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) C1_1 PF00130.17 KNZ71775.1 - 0.032 13.9 2.1 0.066 12.9 1.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 KNZ71775.1 - 1.3 8.7 4.4 2.7 7.7 3.1 1.4 1 0 0 1 1 1 0 PHD-finger DUF4211 PF13926.1 KNZ71776.1 - 3e-33 114.4 0.1 1.5e-32 112.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) TFIID-18kDa PF02269.11 KNZ71777.1 - 1.1e-16 60.3 2.4 1.3e-14 53.7 1.7 2.1 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit RRM_1 PF00076.17 KNZ71778.1 - 6.4e-16 57.7 0.1 2e-15 56.1 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ71778.1 - 2.3e-10 40.3 0.0 3.5e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ71778.1 - 2.5e-08 33.6 0.0 1.6e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KNZ71778.1 - 0.00041 20.0 0.0 0.00063 19.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 KNZ71778.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 KNZ71779.1 - 7.9e-14 51.4 0.1 3.7e-11 42.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ71779.1 - 5e-05 22.4 0.0 0.00053 19.1 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KNZ71779.1 - 0.067 12.2 0.3 0.23 10.4 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2040 PF09745.4 KNZ71780.1 - 1.5e-32 112.1 23.4 1.5e-32 112.1 16.2 3.5 2 2 2 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) RNase_PH PF01138.16 KNZ71781.1 - 1.8e-31 109.1 0.0 2.4e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PvlArgDC PF01862.11 KNZ71781.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) AA_permease_2 PF13520.1 KNZ71782.1 - 2.7e-61 207.3 40.5 3.7e-61 206.9 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KNZ71782.1 - 1.8e-25 89.2 35.2 2.8e-25 88.5 24.3 1.3 1 1 0 1 1 1 1 Amino acid permease HMA PF00403.21 KNZ71783.1 - 2.2e-07 30.9 0.0 3.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain TRM PF02005.11 KNZ71784.1 - 3.5e-121 404.6 0.0 4.3e-121 404.3 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 KNZ71784.1 - 0.0001 22.3 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KNZ71784.1 - 0.00095 18.8 0.0 0.0022 17.6 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein Spermine_synth PF01564.12 KNZ71784.1 - 0.011 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase Methyltransf_18 PF12847.2 KNZ71784.1 - 0.029 14.9 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 KNZ71785.1 - 4.7e-69 232.4 0.0 6.5e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ71785.1 - 5.9e-48 163.1 0.0 8.4e-48 162.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.25 KNZ71785.1 - 7.2e-16 58.1 0.0 1.3e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.1 KNZ71785.1 - 2.4e-15 56.3 0.0 5e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 KNZ71785.1 - 2.9e-14 52.6 0.0 5.5e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 KNZ71785.1 - 2.5e-05 23.4 0.0 0.0012 17.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KNZ71785.1 - 0.24 10.1 0.0 0.43 9.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Alpha-amylase PF00128.19 KNZ71786.1 - 3.6e-20 72.5 9.9 3.6e-17 62.7 0.2 3.6 3 1 0 3 3 3 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KNZ71786.1 - 2.4e-16 59.9 0.0 4.3e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 KNZ71786.1 - 5.1e-09 36.3 0.0 1.2e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KNZ71786.1 - 1.8e-08 34.0 0.0 3.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 PRCC PF10253.4 KNZ71787.1 - 1.6e-30 107.1 8.4 1.6e-30 107.1 5.8 2.3 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Histone PF00125.19 KNZ71788.1 - 2e-21 75.9 0.2 2.8e-21 75.4 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KNZ71788.1 - 1.3e-05 25.1 0.1 3.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KNZ71788.1 - 0.00025 21.2 0.0 0.00044 20.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 KNZ71788.1 - 0.018 15.5 0.4 0.025 15.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.6 KNZ71788.1 - 0.083 12.2 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein SAP PF02037.22 KNZ71791.1 - 7.4e-11 41.2 0.1 1.2e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 SAP domain DUF2315 PF10231.4 KNZ71792.1 - 3e-13 49.7 5.1 1.6e-11 44.1 1.4 2.2 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2315) Nucleoporin_C PF03177.9 KNZ71793.1 - 1.3e-49 169.2 0.0 2e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KNZ71793.1 - 5.5e-18 64.9 0.0 7.7e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like DnaG_DnaB_bind PF08278.6 KNZ71793.1 - 0.021 15.0 0.7 1.1 9.5 0.0 2.7 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding SecM PF06558.7 KNZ71793.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) Histone PF00125.19 KNZ71794.1 - 2e-21 75.9 0.2 2.8e-21 75.4 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KNZ71794.1 - 1.4e-05 25.0 0.1 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KNZ71794.1 - 0.00025 21.2 0.0 0.00044 20.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 KNZ71794.1 - 0.028 14.9 0.4 0.038 14.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.6 KNZ71794.1 - 0.079 12.3 0.1 0.097 12.0 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Methyltransf_11 PF08241.7 KNZ71795.1 - 3.1e-15 56.4 0.0 7.9e-15 55.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ71795.1 - 1.1e-11 45.2 0.0 8.5e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ71795.1 - 9.6e-09 35.1 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ71795.1 - 1.3e-07 32.0 0.0 2.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ71795.1 - 4.4e-07 29.9 0.0 7.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ71795.1 - 9e-06 25.9 0.0 3.4e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ71795.1 - 1.4e-05 24.6 0.0 7.6e-05 22.3 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNZ71795.1 - 4.4e-05 22.7 0.0 6.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 KNZ71795.1 - 0.00097 18.6 0.0 0.0018 17.7 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.1 KNZ71795.1 - 0.0012 19.6 0.2 0.0034 18.2 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 KNZ71795.1 - 0.034 13.1 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Rsm22 PF09243.5 KNZ71795.1 - 0.064 12.2 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 DAGK_cat PF00781.19 KNZ71796.1 - 3e-22 78.4 0.0 6e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain WD40 PF00400.27 KNZ71796.1 - 2.4e-09 36.7 10.5 0.00075 19.2 0.4 5.7 7 0 0 7 7 7 2 WD domain, G-beta repeat Swi3 PF07962.7 KNZ71797.1 - 2.8e-26 90.9 0.0 7.8e-26 89.5 0.0 1.7 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 Methyltransf_PK PF05891.7 KNZ71798.1 - 3e-50 170.5 0.0 1e-48 165.5 0.0 2.2 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 KNZ71798.1 - 6.2e-05 22.7 0.0 9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ71798.1 - 0.0013 19.3 0.0 0.002 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KNZ71798.1 - 0.0024 17.0 0.0 0.0068 15.6 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_11 PF08241.7 KNZ71798.1 - 0.013 15.9 0.0 6 7.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ71798.1 - 0.034 14.6 0.0 8.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ71798.1 - 0.036 14.4 0.0 0.11 12.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain ADK PF00406.17 KNZ71799.1 - 8.8e-46 155.5 0.0 1.2e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KNZ71799.1 - 1.3e-12 47.1 0.0 2.2e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KNZ71799.1 - 2.9e-07 31.3 0.1 5.2e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KNZ71799.1 - 1.1e-06 29.0 0.1 2.6e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KNZ71799.1 - 0.00014 21.7 0.0 0.00083 19.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KNZ71799.1 - 0.033 13.3 0.0 0.05 12.7 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin Epimerase PF01370.16 KNZ71801.1 - 1.9e-12 47.1 0.2 3.5e-09 36.4 0.0 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ71801.1 - 9e-12 45.3 0.0 4e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KNZ71801.1 - 0.00059 18.6 0.0 0.0022 16.7 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KNZ71801.1 - 0.002 17.0 0.1 0.57 9.0 0.0 2.9 3 0 0 3 3 3 1 Male sterility protein adh_short PF00106.20 KNZ71801.1 - 0.009 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KNZ71801.1 - 0.084 11.7 0.0 0.22 10.3 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain DPBB_1 PF03330.13 KNZ71802.1 - 4e-10 39.5 0.1 1.1e-09 38.1 0.1 1.8 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KNZ71802.1 - 3.9e-06 26.5 0.3 7.2e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 Barwin family DUF3246 PF11596.3 KNZ71802.1 - 0.71 9.1 23.0 6.2 6.0 15.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) SCAMP PF04144.8 KNZ71803.1 - 2.5e-43 148.0 9.1 3e-43 147.7 6.3 1.1 1 0 0 1 1 1 1 SCAMP family DUF4200 PF13863.1 KNZ71803.1 - 0.26 11.2 3.2 0.43 10.5 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4231 PF14015.1 KNZ71803.1 - 2.5 8.1 5.3 1.3 9.0 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) RRM_1 PF00076.17 KNZ71804.1 - 2.8e-82 270.3 7.2 2.2e-22 78.4 0.6 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ71804.1 - 3.2e-54 180.7 1.0 5.1e-14 51.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ71804.1 - 2.5e-42 142.5 0.8 2.7e-11 43.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KNZ71804.1 - 1e-27 95.5 1.5 2.2e-27 94.4 0.7 1.9 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 KNZ71804.1 - 1.6e-05 24.7 12.2 0.048 13.5 3.0 3.8 3 1 1 4 4 4 3 RNA binding motif Limkain-b1 PF11608.3 KNZ71804.1 - 3.6e-05 23.4 3.5 0.14 11.8 0.2 3.6 2 1 1 3 3 3 2 Limkain b1 Nup35_RRM_2 PF14605.1 KNZ71804.1 - 9.6e-05 22.0 0.2 1.8 8.3 0.0 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 KNZ71804.1 - 0.0044 17.2 0.0 0.16 12.2 0.0 2.6 2 0 0 2 2 2 1 Cobalamin biosynthesis central region OB_RNB PF08206.6 KNZ71804.1 - 0.0064 15.9 2.6 7.9 6.0 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease B OB domain PNPase PF03726.9 KNZ71804.1 - 0.16 12.2 3.6 0.28 11.4 0.1 2.7 3 0 0 3 3 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF4407 PF14362.1 KNZ71804.1 - 3.9 6.3 6.1 0.83 8.5 0.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Gemini_mov PF01708.11 KNZ71806.1 - 0.029 13.9 0.1 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Geminivirus putative movement protein Ni_hydr_CYTB PF01292.15 KNZ71806.1 - 0.09 12.1 1.9 1.5 8.1 1.6 2.1 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF716 PF04819.7 KNZ71806.1 - 0.21 11.0 4.0 0.44 9.9 0.0 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF716) YwiC PF14256.1 KNZ71806.1 - 0.22 11.5 6.4 0.082 12.9 1.3 2.1 2 0 0 2 2 2 0 YwiC-like protein SRP54 PF00448.17 KNZ71807.1 - 4.7e-74 248.0 0.6 8.7e-74 247.2 0.4 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KNZ71807.1 - 1.1e-16 60.9 0.8 1.1e-16 60.9 0.6 4.3 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.14 KNZ71807.1 - 5.3e-15 55.2 4.8 1.1e-14 54.2 3.3 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KNZ71807.1 - 2.5e-07 30.2 0.1 5.4e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KNZ71807.1 - 3.4e-06 27.0 0.1 6.5e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KNZ71807.1 - 0.00022 20.7 0.4 0.0012 18.3 0.3 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 KNZ71807.1 - 0.00059 18.9 0.1 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin MobB PF03205.9 KNZ71807.1 - 0.00083 19.0 0.1 0.0018 17.9 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 KNZ71807.1 - 0.003 16.3 1.8 0.0057 15.4 0.0 2.3 3 0 0 3 3 3 1 ArgK protein AAA_31 PF13614.1 KNZ71807.1 - 0.029 14.2 0.0 5.1 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2201 PF09967.4 KNZ71807.1 - 0.044 13.7 1.6 0.17 11.8 0.1 2.6 2 1 0 2 2 2 0 VWA-like domain (DUF2201) AAA_17 PF13207.1 KNZ71807.1 - 0.06 14.1 0.0 0.14 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 KNZ71807.1 - 0.073 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_22 PF13401.1 KNZ71807.1 - 0.083 13.0 0.2 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 KNZ71808.1 - 3.5e-15 55.1 19.1 0.0014 18.4 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat SDA1 PF05285.7 KNZ71808.1 - 0.059 12.6 3.8 0.085 12.1 2.6 1.2 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 KNZ71808.1 - 1.2 7.8 12.9 2.1 6.9 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 KNZ71808.1 - 2 6.2 16.5 3.1 5.6 11.4 1.2 1 0 0 1 1 1 0 Nop14-like family SH2_2 PF14633.1 KNZ71809.1 - 1.8e-65 220.0 0.1 1.8e-65 220.0 0.1 2.6 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.1 KNZ71809.1 - 9.3e-31 106.4 0.0 3.5e-30 104.5 0.0 2.0 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 KNZ71809.1 - 1.7e-30 105.4 1.3 1.7e-30 105.4 0.9 2.5 2 0 0 2 2 2 1 Death-like domain of SPT6 HHH_7 PF14635.1 KNZ71809.1 - 1.7e-28 98.7 0.0 4.1e-28 97.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 KNZ71809.1 - 2e-19 69.4 35.1 2e-19 69.4 24.4 5.1 4 1 2 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 KNZ71809.1 - 1.7e-13 50.5 0.1 1.2e-12 47.8 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 KNZ71809.1 - 5.6e-06 26.0 0.0 4.2e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 SH2 domain HHH_3 PF12836.2 KNZ71809.1 - 0.0017 18.2 0.0 0.0094 15.8 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif dCMP_cyt_deam_1 PF00383.17 KNZ71810.1 - 1.9e-11 43.4 0.0 3.5e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AMP-binding PF00501.23 KNZ71811.1 - 1.4e-87 293.8 0.0 2.2e-87 293.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KNZ71811.1 - 3.1e-79 265.9 4.0 2.6e-28 98.7 0.0 5.5 3 2 2 5 5 5 5 Condensation domain PP-binding PF00550.20 KNZ71811.1 - 1.1e-14 54.4 1.7 5.9e-07 29.6 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KNZ71811.1 - 0.012 16.5 0.0 0.045 14.6 0.0 2.1 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KNZ71811.1 - 0.069 11.6 0.0 2.2 6.7 0.0 2.2 2 0 0 2 2 2 0 GH3 auxin-responsive promoter K_oxygenase PF13434.1 KNZ71812.1 - 7.5e-75 251.9 0.0 9e-75 251.7 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KNZ71812.1 - 7.5e-08 32.6 0.0 1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KNZ71812.1 - 9.7e-06 25.6 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNZ71812.1 - 6.4e-05 22.7 0.0 0.00041 20.1 0.0 2.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KNZ71812.1 - 0.0068 16.7 0.0 2.3 8.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KNZ71812.1 - 0.049 12.4 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 KNZ71812.1 - 0.056 12.3 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ribosomal_L24e PF01246.15 KNZ71813.1 - 8.9e-31 105.5 3.4 8.9e-31 105.5 2.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.9 KNZ71813.1 - 0.023 14.3 4.9 0.044 13.4 3.4 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Flu_M1 PF00598.14 KNZ71813.1 - 0.12 11.7 0.6 0.18 11.2 0.4 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M1) ATG_C PF09333.6 KNZ71814.1 - 1.9e-34 117.7 0.0 3.8e-34 116.7 0.0 1.5 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 KNZ71814.1 - 1.1e-09 37.8 0.0 2.9e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG2_CAD PF13329.1 KNZ71814.1 - 0.00045 19.8 0.0 0.0023 17.5 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif Lipase_GDSL_2 PF13472.1 KNZ71815.1 - 8.8e-06 25.9 0.0 1.1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KNZ71815.1 - 9.6e-06 25.5 0.0 1.9e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RPA_C PF08784.6 KNZ71816.1 - 5.6e-17 62.0 0.1 1.3e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KNZ71816.1 - 5.5e-08 32.5 0.3 1.1e-07 31.6 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HTH_6 PF01418.12 KNZ71816.1 - 0.008 15.8 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family NatB_MDM20 PF09797.4 KNZ71817.1 - 1.8e-69 234.2 4.2 1.8e-69 234.2 2.9 1.9 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 KNZ71817.1 - 4.6e-06 26.8 8.4 0.0043 17.3 0.0 4.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ71817.1 - 1.4e-05 25.3 2.4 2.8 8.8 0.0 6.5 4 1 3 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ71817.1 - 0.001 19.6 0.8 0.4 11.4 0.0 4.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ71817.1 - 0.0034 16.9 0.2 0.2 11.3 0.0 3.0 3 0 0 3 3 3 1 TPR repeat BTAD PF03704.12 KNZ71817.1 - 0.0053 17.0 0.1 0.0053 17.0 0.1 3.3 4 1 0 4 4 4 1 Bacterial transcriptional activator domain DUF2665 PF11654.3 KNZ71818.1 - 4.1e-13 48.6 0.1 5.5e-13 48.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) DUF2372 PF10178.4 KNZ71819.1 - 0.00057 19.9 0.1 0.0077 16.3 0.1 2.2 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) TruB_N PF01509.13 KNZ71821.1 - 1.8e-43 148.2 0.0 4.9e-43 146.8 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DHDPS PF00701.17 KNZ71822.1 - 1.9e-30 105.4 0.0 8.6e-30 103.3 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family PNTB PF02233.11 KNZ71823.1 - 2.4e-169 564.0 25.6 2.4e-169 564.0 17.7 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KNZ71823.1 - 1.8e-50 170.7 1.0 4.3e-50 169.5 0.7 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KNZ71823.1 - 6.9e-42 142.6 0.2 2.8e-41 140.7 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KNZ71823.1 - 4.6e-33 113.2 2.9 4.6e-33 113.2 2.0 5.6 5 2 1 6 6 6 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 KNZ71823.1 - 0.007 15.5 3.3 0.4 9.8 0.1 3.4 4 0 0 4 4 4 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 KNZ71823.1 - 0.016 15.1 3.6 0.066 13.2 0.3 3.3 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KNZ71823.1 - 0.02 14.7 0.3 0.052 13.4 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNZ71823.1 - 0.022 14.8 1.4 7 6.6 0.3 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KNZ71823.1 - 0.032 14.3 8.6 2.5 8.1 0.1 4.8 5 1 0 5 5 5 0 Shikimate / quinate 5-dehydrogenase Methyltransf_31 PF13847.1 KNZ71823.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Nuc_sug_transp PF04142.10 KNZ71824.1 - 6.2e-80 267.8 12.1 8.7e-80 267.3 8.4 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 KNZ71824.1 - 1.1e-07 32.0 2.7 1.1e-07 32.0 1.8 2.8 3 0 0 3 3 3 2 Multidrug resistance efflux transporter UAA PF08449.6 KNZ71824.1 - 5.8e-07 28.7 9.0 9.3e-07 28.0 6.2 1.4 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KNZ71824.1 - 4.9e-06 26.2 20.5 0.00086 18.9 0.9 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 KNZ71824.1 - 6.8e-05 22.9 2.5 6.8e-05 22.9 1.7 3.2 4 1 0 4 4 4 2 EamA-like transporter family BRCT PF00533.21 KNZ71826.1 - 2.4e-05 24.4 0.8 0.0013 18.8 0.0 3.6 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain DUF4537 PF15057.1 KNZ71826.1 - 5.7e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.5 KNZ71826.1 - 9.8e-05 22.1 0.1 0.0003 20.6 0.0 1.8 2 0 0 2 2 2 1 Tumour suppressor p53-binding protein-1 Tudor DUF1325 PF07039.6 KNZ71826.1 - 0.02 14.5 0.0 0.053 13.1 0.0 1.7 1 0 0 1 1 1 0 SGF29 tudor-like domain Chromo PF00385.19 KNZ71827.1 - 7e-11 41.6 3.7 1.6e-10 40.4 2.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SNF2_N PF00176.18 KNZ71828.1 - 1.2e-49 168.6 0.1 2.6e-24 85.5 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Rad54_N PF08658.5 KNZ71828.1 - 5.8e-37 127.3 10.6 1.2e-36 126.3 7.3 1.5 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 KNZ71828.1 - 2e-12 46.7 0.0 4.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KNZ71828.1 - 1.5e-07 30.5 0.2 9.2e-07 27.9 0.0 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 GYF PF02213.11 KNZ71829.1 - 4.6e-06 26.1 0.3 1e-05 24.9 0.2 1.6 1 0 0 1 1 1 1 GYF domain PQ-loop PF04193.9 KNZ71830.1 - 3.4e-40 135.3 7.3 3.2e-20 71.4 0.4 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 KNZ71830.1 - 0.06 13.2 0.4 0.06 13.2 0.3 2.1 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange CLTH PF10607.4 KNZ71831.1 - 1.2e-15 57.4 0.0 1.6e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KNZ71831.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 LisH DUF4096 PF13340.1 KNZ71831.1 - 0.082 12.7 0.0 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) LRR_4 PF12799.2 KNZ71832.1 - 0.083 12.5 0.1 0.49 10.0 0.0 2.0 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KNZ71832.1 - 0.11 12.5 0.2 3.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich Repeat Ribosomal_L3 PF00297.17 KNZ71833.1 - 2.4e-37 128.7 1.1 7.4e-36 123.8 0.8 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 p450 PF00067.17 KNZ71834.1 - 9e-52 176.1 0.0 9.4e-51 172.7 0.0 2.6 1 1 0 1 1 1 1 Cytochrome P450 Herpes_Helicase PF02689.9 KNZ71835.1 - 9.5e-08 30.2 0.0 1e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ71835.1 - 0.043 13.9 0.0 0.077 13.1 0.0 1.5 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Ras PF00071.17 KNZ71836.1 - 3.5e-55 185.8 0.0 4.3e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ71836.1 - 2.8e-18 66.5 0.0 4e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ71836.1 - 2.3e-15 56.2 0.0 3e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KNZ71836.1 - 1.1e-07 31.2 0.0 1.3e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KNZ71836.1 - 5.7e-05 22.6 0.0 0.00011 21.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KNZ71836.1 - 0.00022 21.1 0.0 0.00038 20.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KNZ71836.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Arrestin_C PF02752.17 KNZ71837.1 - 0.0014 18.7 2.1 0.0062 16.6 0.3 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KNZ71837.1 - 0.022 14.5 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain ARID PF01388.16 KNZ71838.1 - 1.8e-10 40.5 0.0 3.8e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF3518 PF12031.3 KNZ71838.1 - 0.0045 15.8 0.3 0.068 11.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3518) DUF1764 PF08576.5 KNZ71839.1 - 9.5e-06 26.3 7.3 6.4e-05 23.6 5.1 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) NST1 PF13945.1 KNZ71839.1 - 0.11 12.6 5.4 0.13 12.2 3.8 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator SART-1 PF03343.8 KNZ71839.1 - 0.12 10.6 6.7 0.15 10.4 4.6 1.1 1 0 0 1 1 1 0 SART-1 family Herpes_Helicase PF02689.9 KNZ71840.1 - 9.3e-05 20.3 0.0 9.8e-05 20.3 0.0 1.0 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 KNZ71841.1 - 3.2e-14 52.6 0.0 3.5e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.9 KNZ71842.1 - 1e-53 182.6 0.2 1.2e-53 182.3 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ71842.1 - 0.0087 15.6 0.0 0.014 14.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KNZ71842.1 - 0.041 13.3 0.1 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KNZ71842.1 - 0.073 12.9 0.0 0.19 11.5 0.0 1.6 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KNZ71842.1 - 0.15 12.2 0.1 0.54 10.4 0.1 2.0 1 1 0 1 1 1 0 RNA helicase Helitron_like_N PF14214.1 KNZ71843.1 - 4e-24 85.3 0.0 5.1e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ71843.1 - 0.0029 17.1 0.1 0.0034 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) Gemini_AL1 PF00799.15 KNZ71843.1 - 0.021 14.6 0.1 0.032 14.0 0.1 1.3 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain Helitron_like_N PF14214.1 KNZ71844.1 - 2.2e-16 60.0 0.0 3.9e-15 56.0 0.0 2.1 2 0 0 2 2 2 2 Helitron helicase-like domain at N-terminus AAA_18 PF13238.1 KNZ71845.1 - 1.5e-29 102.8 0.0 2.4e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ71845.1 - 1.2e-14 55.1 0.1 3.1e-14 53.8 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KNZ71845.1 - 5.5e-06 26.3 0.0 0.00015 21.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KNZ71845.1 - 6.3e-05 23.1 0.0 0.00016 21.8 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KNZ71845.1 - 8.5e-05 22.7 0.0 0.00015 21.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KNZ71845.1 - 8.7e-05 22.5 0.0 0.00024 21.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 KNZ71845.1 - 0.0001 22.2 0.1 0.00066 19.5 0.1 1.9 1 1 0 1 1 1 1 Shikimate kinase AAA_19 PF13245.1 KNZ71845.1 - 0.00045 19.9 0.1 0.00083 19.0 0.1 1.3 1 0 0 1 1 1 1 Part of AAA domain Thymidylate_kin PF02223.12 KNZ71845.1 - 0.0024 17.2 0.0 0.72 9.1 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase KTI12 PF08433.5 KNZ71845.1 - 0.0051 16.0 0.0 0.0092 15.2 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 KaiC PF06745.8 KNZ71845.1 - 0.0057 15.7 0.0 0.26 10.3 0.0 2.1 2 0 0 2 2 2 1 KaiC AAA_14 PF13173.1 KNZ71845.1 - 0.0061 16.4 0.0 0.019 14.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain ArgK PF03308.11 KNZ71845.1 - 0.0064 15.2 0.1 0.022 13.5 0.0 1.8 2 0 0 2 2 2 1 ArgK protein ABC_tran PF00005.22 KNZ71845.1 - 0.0065 16.7 0.0 0.0086 16.3 0.0 1.5 1 1 0 1 1 1 1 ABC transporter Cytidylate_kin2 PF13189.1 KNZ71845.1 - 0.0096 15.8 0.1 0.95 9.3 0.0 2.1 1 1 1 2 2 2 1 Cytidylate kinase-like family RuvB_N PF05496.7 KNZ71845.1 - 0.015 14.3 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 KNZ71845.1 - 0.017 13.8 0.0 0.023 13.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein dNK PF01712.14 KNZ71845.1 - 0.023 14.5 0.1 0.036 13.9 0.1 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase Viral_helicase1 PF01443.13 KNZ71845.1 - 0.024 14.1 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KNZ71845.1 - 0.024 14.8 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ADK PF00406.17 KNZ71845.1 - 0.024 14.5 0.1 0.75 9.6 0.0 2.4 2 1 0 2 2 2 0 Adenylate kinase Sigma54_activ_2 PF14532.1 KNZ71845.1 - 0.027 14.5 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.10 KNZ71845.1 - 0.031 14.0 0.4 0.2 11.3 0.1 2.1 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.4 KNZ71845.1 - 0.048 12.6 0.3 0.07 12.0 0.2 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 KNZ71845.1 - 0.055 13.4 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 KNZ71845.1 - 0.066 12.9 0.1 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 KNZ71845.1 - 0.07 12.0 0.1 0.14 11.0 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 KNZ71845.1 - 0.072 12.5 0.1 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 KNZ71845.1 - 0.073 12.1 0.0 0.48 9.4 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.17 KNZ71845.1 - 0.077 11.8 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 KNZ71845.1 - 0.14 11.7 0.1 0.33 10.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KNZ71845.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Sin_N PF04801.8 KNZ71846.1 - 3.2e-16 59.2 3.4 8e-16 57.9 2.4 1.6 1 1 0 1 1 1 1 Sin-like protein conserved region DnaJ PF00226.26 KNZ71848.1 - 8.7e-21 73.4 0.7 1.3e-20 72.8 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 KNZ71848.1 - 0.0084 16.1 1.4 0.013 15.5 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Gly-zipper_YMGG PF13441.1 KNZ71848.1 - 1.2 8.7 5.9 1.9 8.0 4.1 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.4 KNZ71848.1 - 1.8 8.7 7.1 3.6 7.7 5.0 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Pex24p PF06398.6 KNZ71849.1 - 0.098 11.4 2.5 0.13 11.0 1.7 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin LIM PF00412.17 KNZ71852.1 - 1.3e-11 44.3 24.7 9e-06 25.6 3.1 5.4 5 0 0 5 5 5 3 LIM domain HhH-GPD PF00730.20 KNZ71853.1 - 6.1e-06 26.4 0.0 7.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein FMN_dh PF01070.13 KNZ71854.1 - 1e-99 333.8 0.0 1.2e-99 333.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KNZ71854.1 - 2e-22 78.7 0.0 3.9e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KNZ71854.1 - 0.0078 15.1 0.1 0.027 13.3 0.0 1.8 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 KNZ71854.1 - 0.01 14.7 0.5 0.13 11.1 0.1 2.7 2 1 1 3 3 3 0 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KNZ71854.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase DUF1270 PF06900.6 KNZ71854.1 - 0.07 13.2 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) NUDE_C PF04880.8 KNZ71855.1 - 5.3e-05 23.6 1.0 5.3e-05 23.6 0.7 2.8 3 3 1 4 4 4 1 NUDE protein, C-terminal conserved region NPV_P10 PF05531.7 KNZ71855.1 - 0.089 13.0 0.3 0.18 12.0 0.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SAP PF02037.22 KNZ71855.1 - 0.1 12.1 0.3 0.22 11.0 0.2 1.5 1 0 0 1 1 1 0 SAP domain FliD_N PF02465.13 KNZ71855.1 - 0.11 12.8 1.4 0.2 12.0 0.1 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Pkinase PF00069.20 KNZ71856.1 - 1.1e-66 224.7 0.0 1.2e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ71856.1 - 6.2e-26 91.0 0.0 1e-25 90.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ71856.1 - 5.8e-06 25.4 0.0 8.6e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ71856.1 - 0.063 12.9 0.3 0.17 11.5 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KNZ71856.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Helitron_like_N PF14214.1 KNZ71857.1 - 8.5e-08 32.1 0.9 1.7e-07 31.1 0.6 1.6 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus Gemini_AL1 PF00799.15 KNZ71857.1 - 0.11 12.3 1.0 0.12 12.1 0.7 1.2 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain PIF1 PF05970.9 KNZ71859.1 - 7.9e-28 97.4 0.1 8.5e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 KNZ71859.1 - 0.0046 16.7 0.0 0.0049 16.7 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KNZ71859.1 - 0.016 14.7 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KNZ71859.1 - 0.064 12.7 0.1 0.072 12.5 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 KNZ71859.1 - 0.08 12.1 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.1 KNZ71859.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Torsin PF06309.6 KNZ71859.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Torsin Aldo_ket_red PF00248.16 KNZ71860.1 - 5.7e-66 222.2 0.0 6.4e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PAN_4 PF14295.1 KNZ71861.1 - 1.7 8.4 9.4 0.045 13.4 1.5 2.3 3 1 0 3 3 3 0 PAN domain Transp_cyt_pur PF02133.10 KNZ71862.1 - 1.1e-112 376.7 35.9 1.3e-112 376.5 24.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase PF00069.20 KNZ71863.1 - 2.4e-51 174.4 0.0 3.6e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ71863.1 - 8.4e-48 162.6 0.0 1.2e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KNZ71863.1 - 3.2e-07 29.9 6.6 7.2e-07 28.8 4.6 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.18 KNZ71863.1 - 0.021 14.5 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KNZ71863.1 - 0.059 12.3 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KNZ71863.1 - 0.089 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_3 PF07649.7 KNZ71863.1 - 0.097 12.7 4.5 0.22 11.5 3.1 1.7 1 0 0 1 1 1 0 C1-like domain PHD PF00628.24 KNZ71863.1 - 0.79 9.4 9.9 2 8.1 6.9 1.7 1 0 0 1 1 1 0 PHD-finger Mito_carr PF00153.22 KNZ71864.1 - 3.6e-23 81.0 3.6 1.6e-15 56.5 0.2 2.6 3 0 0 3 3 3 2 Mitochondrial carrier protein SE PF08491.5 KNZ71868.1 - 2.5e-94 315.1 0.0 3.1e-94 314.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 KNZ71868.1 - 0.0004 19.5 0.0 0.0009 18.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KNZ71868.1 - 0.012 14.5 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 4HBT PF03061.17 KNZ71869.1 - 1.2e-07 31.7 0.0 0.0036 17.3 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily DUF1688 PF07958.6 KNZ71871.1 - 6.5e-151 502.6 0.0 7.4e-151 502.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) XPG_I PF00867.13 KNZ71872.1 - 2e-18 66.1 0.0 7.8e-18 64.3 0.0 2.1 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KNZ71872.1 - 0.00087 19.5 0.0 0.0034 17.6 0.0 2.1 1 1 0 1 1 1 1 XPG N-terminal domain Glyco_hydro_3 PF00933.16 KNZ71873.1 - 8.2e-62 208.8 0.0 1.1e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DUF1888 PF08985.6 KNZ71873.1 - 0.14 11.8 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1888) VHS PF00790.14 KNZ71874.1 - 4.3e-07 29.6 0.0 9.2e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 VHS domain Pkinase PF00069.20 KNZ71875.1 - 4.6e-25 88.2 0.0 4.5e-21 75.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ71875.1 - 6.9e-20 71.2 0.0 1.4e-16 60.3 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KNZ71875.1 - 0.0022 17.7 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KNZ71875.1 - 0.075 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Fructosamin_kin PF03881.9 KNZ71875.1 - 0.099 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase RRM_1 PF00076.17 KNZ71876.1 - 1.1e-35 121.0 0.2 5.3e-17 61.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ71876.1 - 2.3e-28 97.9 0.1 7.9e-15 54.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ71876.1 - 4.9e-14 51.9 0.1 1.8e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KNZ71876.1 - 0.0024 17.7 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif OB_RNB PF08206.6 KNZ71876.1 - 0.0026 17.2 0.0 0.79 9.2 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain VHS PF00790.14 KNZ71877.1 - 9.7e-08 31.7 0.1 3e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KNZ71877.1 - 1.2e-07 31.6 0.3 4.5e-07 29.7 0.2 1.9 1 1 0 1 1 1 1 GAT domain AA_permease_2 PF13520.1 KNZ71878.1 - 3e-58 197.3 51.9 3.8e-58 197.0 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KNZ71878.1 - 1.2e-14 53.5 47.3 1.7e-14 53.0 32.8 1.1 1 0 0 1 1 1 1 Amino acid permease Amino_oxidase PF01593.19 KNZ71880.1 - 9.1e-62 209.5 0.0 5.5e-60 203.7 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KNZ71880.1 - 5e-11 42.4 0.3 1.5e-10 40.9 0.2 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KNZ71880.1 - 7.2e-05 22.9 0.3 0.017 15.2 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KNZ71880.1 - 0.0025 16.9 0.2 0.0041 16.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KNZ71880.1 - 0.007 15.3 0.2 0.18 10.6 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ71880.1 - 0.0089 14.9 0.5 0.015 14.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KNZ71880.1 - 0.018 14.1 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KNZ71880.1 - 0.034 14.2 0.1 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KNZ71880.1 - 0.14 12.5 1.1 1 9.7 0.4 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KNZ71880.1 - 0.15 11.6 0.1 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 KNZ71880.1 - 0.19 10.1 0.4 0.43 8.9 0.3 1.6 1 0 0 1 1 1 0 HI0933-like protein DUF89 PF01937.14 KNZ71881.1 - 1.3e-87 293.9 0.0 1.2e-78 264.3 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function DUF89 BolA PF01722.13 KNZ71883.1 - 2.2e-20 72.4 0.0 2.5e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Amidohydro_2 PF04909.9 KNZ71884.1 - 6.4e-28 98.0 0.1 1.4e-27 96.9 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase Adenylsucc_synt PF00709.16 KNZ71885.1 - 3.4e-157 523.4 0.0 3.9e-157 523.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase MCD PF05292.6 KNZ71885.1 - 0.031 12.9 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase (MCD) COX16 PF14138.1 KNZ71886.1 - 1.2e-28 99.0 0.0 1.5e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 ATP-synt_J PF04911.7 KNZ71887.1 - 1.4e-19 69.2 0.0 1.8e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase j chain Clathrin PF00637.15 KNZ71888.1 - 3.5e-19 68.8 1.3 3.4e-13 49.4 0.7 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 KNZ71888.1 - 0.0047 16.7 0.1 0.012 15.4 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 KNZ71888.1 - 0.012 15.3 7.6 0.022 14.4 5.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.1 KNZ71888.1 - 0.036 13.8 2.0 0.094 12.5 1.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 KNZ71888.1 - 0.038 14.0 7.0 0.073 13.1 4.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 KNZ71888.1 - 0.046 13.3 0.5 0.53 9.9 0.0 2.8 3 0 0 3 3 3 0 TPR repeat zf-rbx1 PF12678.2 KNZ71888.1 - 0.094 12.8 3.1 0.23 11.5 2.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 KNZ71888.1 - 0.21 11.4 8.1 0.44 10.4 5.6 1.6 1 0 0 1 1 1 0 Ring finger domain TPR_16 PF13432.1 KNZ71888.1 - 0.6 10.8 5.6 9.4 7.0 1.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Antistasin PF02822.9 KNZ71889.1 - 0.12 12.6 0.6 0.24 11.7 0.4 1.5 1 0 0 1 1 1 0 Antistasin family HSP70 PF00012.15 KNZ71890.1 - 5.2e-267 886.6 8.1 6e-267 886.4 5.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KNZ71890.1 - 4.2e-19 68.3 1.4 4.1e-18 65.0 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 KNZ71890.1 - 0.0027 16.8 3.9 0.0084 15.2 0.2 2.8 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.5 KNZ71890.1 - 0.0045 15.8 0.5 0.21 10.4 0.2 2.5 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 KNZ71890.1 - 1.5 8.6 5.3 28 4.5 0.1 3.7 2 1 0 2 2 2 0 Cell division protein FtsA Acetyltransf_1 PF00583.19 KNZ71891.1 - 2.6e-17 62.6 0.0 4e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KNZ71891.1 - 2.7e-09 36.6 0.0 4.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KNZ71891.1 - 2.2e-08 34.0 0.0 2.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNZ71891.1 - 9.3e-08 32.2 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KNZ71891.1 - 3.5e-07 30.2 0.0 6.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KNZ71891.1 - 2.4e-06 27.7 0.0 3.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KNZ71891.1 - 1.1e-05 25.2 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KNZ71891.1 - 0.0028 17.6 0.0 0.0042 17.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KNZ71891.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 KNZ71891.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PP2C PF00481.16 KNZ71895.1 - 3.5e-75 252.6 0.1 5.1e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KNZ71895.1 - 8e-06 25.3 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C GMC_oxred_N PF00732.14 KNZ71896.1 - 1.9e-61 207.8 0.0 2.9e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ71896.1 - 8.2e-36 123.4 0.3 1.6e-35 122.5 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KNZ71896.1 - 0.0001 22.2 0.0 0.0003 20.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KNZ71896.1 - 0.00015 20.8 0.0 0.00022 20.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KNZ71896.1 - 0.00018 20.5 0.0 0.0011 17.9 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ71896.1 - 0.00021 20.2 0.0 0.0081 15.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KNZ71896.1 - 0.0016 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KNZ71896.1 - 0.067 11.6 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KNZ71896.1 - 0.086 11.9 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family YL1_C PF08265.6 KNZ71897.1 - 2.1e-15 55.9 0.3 3.1e-15 55.3 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CPL PF08144.6 KNZ71898.1 - 1.7e-19 70.1 0.0 1.5e-18 67.0 0.0 2.5 2 1 1 3 3 3 1 CPL (NUC119) domain DUF4282 PF14110.1 KNZ71899.1 - 0.049 13.8 0.1 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) Chromo PF00385.19 KNZ71900.1 - 6.4e-10 38.5 0.1 8e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KNZ71900.1 - 0.032 14.1 0.1 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 NST1 PF13945.1 KNZ71902.1 - 2.1e-56 191.0 0.0 2.1e-56 191.0 0.0 5.1 2 1 3 5 5 5 1 Salt tolerance down-regulator NdhN PF11909.3 KNZ71903.1 - 0.023 14.0 0.0 0.077 12.3 0.0 1.8 2 0 0 2 2 2 0 NADH-quinone oxidoreductase cyanobacterial subunit N CBM_5_12 PF02839.9 KNZ71903.1 - 0.13 11.9 0.3 0.28 10.7 0.2 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain LRR_4 PF12799.2 KNZ71904.1 - 0.12 12.0 0.2 1.4 8.6 0.0 2.7 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) TPR_11 PF13414.1 KNZ71904.1 - 0.16 11.6 0.2 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 TPR repeat LRR_8 PF13855.1 KNZ71904.1 - 1.7 8.4 5.1 1.4 8.7 0.1 3.2 4 0 0 4 4 4 0 Leucine rich repeat ACOX PF01756.14 KNZ71905.1 - 1e-21 77.1 0.2 3.1e-21 75.6 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KNZ71905.1 - 1.7e-17 63.8 0.0 3.3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KNZ71905.1 - 5.8e-09 35.3 0.1 3.2e-08 32.9 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KNZ71905.1 - 0.00018 21.6 0.0 0.00018 21.6 0.0 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain La PF05383.12 KNZ71906.1 - 7.2e-19 67.3 0.0 1.5e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_3 PF08777.6 KNZ71906.1 - 8.5e-05 22.3 0.1 0.00037 20.2 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif RRM_1 PF00076.17 KNZ71906.1 - 9.4e-05 21.9 0.4 0.00026 20.5 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ71906.1 - 9.6e-05 22.2 0.1 0.00065 19.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.22 KNZ71907.1 - 2.6e-37 126.3 1.6 4e-13 48.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.19 KNZ71913.1 - 6.7e-83 278.7 14.9 8.1e-83 278.4 10.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ71913.1 - 2.5e-24 85.6 36.3 7.7e-16 57.7 9.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KNZ71913.1 - 0.051 13.6 8.1 1.1 9.3 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) TPR_16 PF13432.1 KNZ71913.1 - 3.7 8.3 5.4 25 5.6 0.9 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat SH3_2 PF07653.12 KNZ71914.1 - 0.045 13.2 0.0 0.067 12.6 0.0 1.5 1 1 0 1 1 1 0 Variant SH3 domain Glyoxalase_4 PF13669.1 KNZ71917.1 - 0.057 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DNA_pol_B_palm PF14792.1 KNZ71918.1 - 1.2e-26 92.9 0.0 2.9e-26 91.7 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 KNZ71918.1 - 1.7e-18 65.9 0.4 3e-17 61.8 0.0 2.7 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 KNZ71918.1 - 2e-17 62.6 0.0 5.7e-17 61.1 0.0 1.9 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 KNZ71918.1 - 5.7e-15 55.2 0.6 1.8e-14 53.6 0.3 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.18 KNZ71918.1 - 0.0003 20.3 0.3 0.003 17.1 0.1 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif BRCT PF00533.21 KNZ71918.1 - 0.00075 19.5 0.0 0.0088 16.1 0.0 2.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain CAF-1_p150 PF11600.3 KNZ71918.1 - 0.0051 16.2 4.7 0.0051 16.2 3.3 3.0 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal HHH_5 PF14520.1 KNZ71918.1 - 0.012 15.7 1.1 2.2 8.4 0.0 3.5 3 0 0 3 3 3 0 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 KNZ71918.1 - 0.019 15.3 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Methyltransf_23 PF13489.1 KNZ71919.1 - 3.1e-12 46.5 0.0 4.9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ71919.1 - 3.3e-11 42.9 0.0 1.3e-10 41.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ71919.1 - 3.6e-08 33.7 0.0 6.7e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KNZ71919.1 - 4.3e-07 29.1 0.0 2.8e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 KNZ71919.1 - 1.3e-06 28.7 0.0 4.8e-06 26.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ71919.1 - 1.7e-05 25.1 0.0 5e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ71919.1 - 0.0017 18.9 0.0 0.012 16.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ71919.1 - 0.0044 17.0 0.0 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNZ71919.1 - 0.0063 15.6 0.0 0.26 10.3 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 KNZ71919.1 - 0.018 15.0 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Peptidase_M16 PF00675.15 KNZ71920.1 - 5.2e-26 91.1 0.1 8.7e-26 90.4 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KNZ71920.1 - 1.6e-07 31.2 0.0 0.00029 20.5 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Uteroglobin PF01099.12 KNZ71920.1 - 0.69 9.7 2.2 16 5.4 0.1 2.6 2 0 0 2 2 2 0 Uteroglobin family Peptidase_S9 PF00326.16 KNZ71925.1 - 8e-25 87.3 0.0 1.1e-22 80.3 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KNZ71925.1 - 6.6e-06 26.1 0.4 1.5e-05 25.0 0.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ71925.1 - 6.4e-05 22.7 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ71925.1 - 0.031 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KNZ71925.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1513 PF07433.6 KNZ71925.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) Ycf4 PF02392.11 KNZ71925.1 - 0.53 9.5 29.1 12 5.1 0.5 5.7 1 1 3 4 4 4 0 Ycf4 Ribosomal_60s PF00428.14 KNZ71926.1 - 3.5e-26 91.4 6.8 3.5e-26 91.4 4.7 1.7 2 0 0 2 2 2 1 60s Acidic ribosomal protein MMR_HSR1 PF01926.18 KNZ71927.1 - 1.9e-06 27.8 0.0 4.9e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KNZ71927.1 - 3.6e-06 27.4 0.0 0.00011 22.6 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein Septin PF00735.13 KNZ71927.1 - 0.002 17.1 0.0 0.012 14.6 0.0 2.0 1 1 0 1 1 1 1 Septin MobB PF03205.9 KNZ71927.1 - 0.026 14.2 0.0 0.077 12.7 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KNZ71927.1 - 0.04 13.0 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KNZ71927.1 - 0.044 13.7 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KNZ71927.1 - 0.069 13.2 0.0 0.34 11.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KNZ71927.1 - 0.076 12.5 0.1 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.17 KNZ71927.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 KNZ71927.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter HUN PF08729.5 KNZ71928.1 - 2.1e-12 46.6 1.0 5.1e-12 45.4 0.7 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 KNZ71928.1 - 9.1e-06 25.4 6.5 3.3e-05 23.6 0.2 2.8 2 1 0 2 2 2 1 Ubinuclein conserved middle domain Mito_fiss_reg PF05308.6 KNZ71928.1 - 0.2 11.0 6.6 0.5 9.6 4.6 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator ACPS PF01648.15 KNZ71929.1 - 0.0019 17.9 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Peptidase_C33 PF05412.7 KNZ71929.1 - 0.029 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase Asp_protease_2 PF13650.1 KNZ71931.1 - 8.6e-05 22.9 0.0 0.0002 21.7 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.5 KNZ71931.1 - 0.00031 20.3 0.2 0.0052 16.3 0.1 2.1 1 1 1 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 KNZ71931.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease E1-E2_ATPase PF00122.15 KNZ71935.1 - 6.4e-50 169.3 2.2 6.4e-50 169.3 1.5 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KNZ71935.1 - 1.4e-40 138.7 5.8 1.4e-40 138.7 4.0 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KNZ71935.1 - 5.7e-29 102.0 0.0 5.2e-28 98.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KNZ71935.1 - 6.8e-19 67.6 0.0 1.3e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KNZ71935.1 - 8.7e-13 48.8 0.0 4.4e-12 46.5 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KNZ71935.1 - 3e-06 26.5 0.0 7.6e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KNZ71935.1 - 0.00018 21.1 0.4 0.00061 19.4 0.4 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2839 PF10999.3 KNZ71935.1 - 0.28 11.2 2.4 29 4.7 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) E1-E2_ATPase PF00122.15 KNZ71936.1 - 7.1e-50 169.1 4.1 7.1e-50 169.1 2.8 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KNZ71936.1 - 4.5e-43 146.9 3.0 4.5e-43 146.9 2.1 3.2 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KNZ71936.1 - 2.3e-32 113.1 0.0 6e-32 111.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KNZ71936.1 - 3.2e-20 71.8 0.0 9.9e-20 70.2 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KNZ71936.1 - 2.6e-14 53.8 0.0 9.5e-14 51.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KNZ71936.1 - 4.4e-09 35.6 0.0 1.1e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KNZ71936.1 - 0.00016 21.3 1.9 0.00069 19.2 0.6 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase AMP-binding PF00501.23 KNZ71938.1 - 8.5e-24 83.6 0.0 1.6e-22 79.5 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.8 KNZ71938.1 - 0.026 13.0 0.1 0.039 12.4 0.1 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter Tyr-DNA_phospho PF06087.7 KNZ71939.1 - 6.2e-51 173.4 0.0 1.2e-50 172.4 0.0 1.3 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KNZ71939.1 - 0.006 16.3 0.0 0.71 9.6 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Lipase_GDSL PF00657.17 KNZ71940.1 - 0.026 14.3 0.3 0.033 14.0 0.2 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Xpo1 PF08389.7 KNZ71941.1 - 5.7e-12 45.7 0.6 1.4e-09 38.0 0.1 3.7 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 KNZ71941.1 - 0.0003 20.6 0.1 0.0035 17.2 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Flu_M1_C PF08289.6 KNZ71941.1 - 0.00073 19.5 0.0 0.0028 17.6 0.0 2.0 1 0 0 1 1 1 1 Influenza Matrix protein (M1) C-terminal domain DUF2424 PF10340.4 KNZ71944.1 - 4.5e-23 81.4 0.0 6.3e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 KNZ71944.1 - 1.1e-19 70.9 0.0 1.6e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold His_kinase PF06580.8 KNZ71944.1 - 0.15 12.0 0.0 14 5.6 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase DUF2424 PF10340.4 KNZ71945.1 - 4.7e-20 71.5 0.0 6.7e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 KNZ71945.1 - 6.4e-20 71.6 0.0 9.3e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ71945.1 - 0.00059 19.5 0.0 0.00089 19.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ71945.1 - 0.0041 17.0 0.0 0.006 16.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AMP-binding PF00501.23 KNZ71947.1 - 2e-86 289.9 0.2 2.7e-86 289.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2424 PF10340.4 KNZ71948.1 - 3.8e-22 78.4 0.0 5.5e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 KNZ71948.1 - 3.6e-20 72.4 0.0 5e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold WD40 PF00400.27 KNZ71949.1 - 0.00023 20.9 6.0 1.2 9.1 0.0 5.2 5 2 1 6 6 6 2 WD domain, G-beta repeat tRNA-synt_1f PF01921.13 KNZ71949.1 - 0.18 10.4 0.1 0.55 8.8 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (K) Glyco_hydro_38 PF01074.17 KNZ71950.1 - 4.9e-78 262.1 0.2 7.7e-78 261.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KNZ71950.1 - 1.8e-61 208.3 0.0 3.1e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KNZ71950.1 - 1e-07 32.0 0.0 2.8e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase, middle domain MMR_HSR1 PF01926.18 KNZ71951.1 - 0.00032 20.6 0.0 0.0042 17.0 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KNZ71951.1 - 0.0012 19.3 0.0 0.0075 16.7 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein ATP_bind_1 PF03029.12 KNZ71951.1 - 0.0029 17.1 0.2 0.011 15.3 0.1 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KNZ71952.1 - 3.6e-08 33.3 0.0 1.3e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KNZ71952.1 - 3.6e-05 24.2 0.0 0.00017 22.0 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ71952.1 - 0.00023 20.4 0.0 0.00049 19.3 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KNZ71952.1 - 0.00083 18.1 0.6 0.012 14.3 0.0 2.3 2 1 0 2 2 2 1 G-protein alpha subunit DUF2326 PF10088.4 KNZ71952.1 - 0.0015 18.1 0.3 0.0034 17.0 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2326) Arch_ATPase PF01637.13 KNZ71952.1 - 0.006 16.3 0.3 0.017 14.8 0.2 2.0 1 1 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 KNZ71952.1 - 0.0091 16.8 0.1 0.017 15.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 KNZ71952.1 - 0.01 15.5 0.3 0.023 14.4 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KNZ71952.1 - 0.013 15.0 0.0 0.055 12.9 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 KNZ71952.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KNZ71952.1 - 0.015 15.4 0.0 0.077 13.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain Septin PF00735.13 KNZ71952.1 - 0.016 14.2 0.0 0.21 10.5 0.0 2.3 3 0 0 3 3 3 0 Septin GTP_EFTU PF00009.22 KNZ71952.1 - 0.019 14.3 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KNZ71952.1 - 0.021 14.6 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Transaldolase PF00923.14 KNZ71953.1 - 2.9e-60 203.8 0.0 3.7e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Transaldolase AAA_12 PF13087.1 KNZ71955.1 - 3.6e-32 111.3 0.1 8.1e-32 110.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KNZ71955.1 - 9.7e-17 61.3 0.0 8e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KNZ71955.1 - 2.7e-13 49.9 0.0 7.3e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KNZ71955.1 - 1e-08 34.8 0.0 3.5e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 KNZ71955.1 - 1.6e-05 24.5 0.2 0.47 9.9 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 KNZ71955.1 - 2.1e-05 23.8 0.0 0.0014 17.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.1 KNZ71955.1 - 0.0042 17.2 0.0 0.085 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KNZ71955.1 - 0.0085 16.3 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KNZ71955.1 - 0.013 15.3 0.2 0.04 13.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain UvrD_C PF13361.1 KNZ71955.1 - 0.018 14.5 0.1 0.042 13.2 0.0 1.6 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.4 KNZ71955.1 - 0.022 13.7 0.1 3.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 KNZ71955.1 - 0.024 14.6 0.0 0.089 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain UvrD_C_2 PF13538.1 KNZ71955.1 - 0.05 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.9 KNZ71955.1 - 0.066 12.8 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Helicase NACHT PF05729.7 KNZ71955.1 - 0.071 12.7 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Flavi_DEAD PF07652.9 KNZ71955.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_17 PF13207.1 KNZ71955.1 - 0.13 13.1 0.0 0.76 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 KNZ71955.1 - 0.14 11.6 0.0 1.2 8.6 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase PMSR PF01625.16 KNZ71956.1 - 4.8e-58 195.4 0.1 5.7e-58 195.2 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase UCR_hinge PF02320.11 KNZ71957.1 - 1.5e-08 34.4 1.8 2.6e-08 33.6 1.2 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.5 KNZ71957.1 - 3.2 7.5 6.9 0.14 11.9 0.8 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF106 PF01956.11 KNZ71959.1 - 0.28 10.7 3.4 15 5.0 0.0 2.2 1 1 1 2 2 2 0 Integral membrane protein DUF106 DUF1917 PF08939.5 KNZ71960.1 - 1.6e-44 152.4 0.1 4.8e-38 131.2 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF1917) Hormone_2 PF00123.15 KNZ71960.1 - 0.036 13.9 0.1 0.082 12.7 0.1 1.7 1 0 0 1 1 1 0 Peptide hormone Aldedh PF00171.17 KNZ71961.1 - 1.6e-72 244.3 0.0 2e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Dynamin_M PF01031.15 KNZ71962.1 - 3.4e-25 88.4 0.0 2.3e-17 62.7 0.0 2.9 3 0 0 3 3 3 2 Dynamin central region Dynamin_N PF00350.18 KNZ71962.1 - 7.3e-22 77.9 0.0 1.6e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KNZ71962.1 - 1.5e-09 37.5 0.6 1e-08 34.9 0.2 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_29 PF13555.1 KNZ71962.1 - 0.018 14.5 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KNZ71962.1 - 0.1 12.8 0.0 0.35 11.1 0.0 2.0 1 1 0 1 1 1 0 ABC transporter MFS_1 PF07690.11 KNZ71963.1 - 2.3e-35 121.9 41.9 3.4e-35 121.4 29.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily BacteriocIIc_cy PF12173.3 KNZ71963.1 - 0.023 14.7 1.5 0.081 12.9 1.1 2.0 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like Oxidored_FMN PF00724.15 KNZ71964.1 - 7.7e-97 324.3 0.0 9.3e-97 324.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF3602 PF12223.3 KNZ71965.1 - 2.9e-24 85.2 34.2 3.3e-05 24.1 0.5 6.1 1 1 5 6 6 6 6 Protein of unknown function (DUF3602) DUF2422 PF10337.4 KNZ71966.1 - 2.2e-64 217.9 0.0 4e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KNZ71966.1 - 1.3e-49 168.8 0.0 2e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KNZ71966.1 - 4.4e-09 36.3 13.8 4.4e-09 36.3 9.6 3.5 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 KNZ71966.1 - 1.6 7.2 10.1 4.3 5.8 7.0 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter Asp_protease_2 PF13650.1 KNZ71968.1 - 0.0056 17.1 0.0 0.014 15.8 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease ICMT PF04140.9 KNZ71969.1 - 3.9e-11 43.0 1.3 5.7e-11 42.4 0.1 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KNZ71969.1 - 8.8e-11 41.8 1.1 1.6e-09 37.8 0.8 2.3 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KNZ71969.1 - 0.063 11.8 0.5 0.094 11.2 0.4 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family MFS_1 PF07690.11 KNZ71970.1 - 6.2e-20 71.2 19.4 1.2e-19 70.3 13.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily ImcF-related_N PF14331.1 KNZ71971.1 - 0.0088 14.9 0.2 0.018 13.9 0.1 1.5 1 0 0 1 1 1 1 ImcF-related N-terminal domain GTP_EFTU PF00009.22 KNZ71971.1 - 0.032 13.6 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Aldo_ket_red PF00248.16 KNZ71972.1 - 2.7e-59 200.3 0.0 5.8e-59 199.2 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1896 PF08989.5 KNZ71974.1 - 0.054 13.3 0.1 10 6.0 0.0 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF1896) Daxx PF03344.10 KNZ71975.1 - 0.28 9.6 23.0 0.29 9.5 15.9 1.0 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 KNZ71975.1 - 0.95 8.8 12.8 1.1 8.6 8.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO CENP-T PF15511.1 KNZ71975.1 - 1 8.5 19.6 1.2 8.3 13.6 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 KNZ71975.1 - 1.5 6.6 28.3 1.7 6.4 19.6 1.0 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.12 KNZ71975.1 - 2.5 7.8 9.1 3.1 7.5 6.3 1.1 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 KNZ71975.1 - 2.7 6.9 6.1 3.1 6.7 4.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SDA1 PF05285.7 KNZ71975.1 - 2.8 7.1 27.4 3.3 6.9 19.0 1.0 1 0 0 1 1 1 0 SDA1 Ycf1 PF05758.7 KNZ71975.1 - 3.9 5.0 11.5 4.4 4.8 8.0 1.0 1 0 0 1 1 1 0 Ycf1 Fibrinogen_aC PF12160.3 KNZ71975.1 - 4.2 6.9 8.7 0.45 10.0 2.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha C domain DUF1510 PF07423.6 KNZ71975.1 - 5 6.4 24.8 6.4 6.0 17.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF913 PF06025.7 KNZ71975.1 - 5.2 5.7 6.2 6.4 5.4 4.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BTV_NS2 PF04514.7 KNZ71975.1 - 6 5.6 12.9 7.6 5.3 9.0 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 BUD22 PF09073.5 KNZ71975.1 - 6.3 5.7 28.5 7.4 5.5 19.8 1.0 1 0 0 1 1 1 0 BUD22 Trypan_PARP PF05887.6 KNZ71975.1 - 7 6.4 15.6 8.9 6.1 10.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Herpes_LMP1 PF05297.6 KNZ71975.1 - 7.5 5.3 9.2 8.9 5.1 6.4 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PPP4R2 PF09184.6 KNZ71975.1 - 9.2 5.7 25.0 11 5.4 17.3 1.1 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.9 KNZ71975.1 - 9.7 4.0 21.8 11 3.8 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1349 PF07081.6 KNZ71979.1 - 1.2e-10 40.9 0.0 1.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) PLAC8 PF04749.12 KNZ71980.1 - 1.7e-24 86.4 7.8 2e-24 86.1 5.4 1.1 1 0 0 1 1 1 1 PLAC8 family Glyco_hydro_10 PF00331.15 KNZ71984.1 - 6.9e-27 94.3 0.6 5.5e-15 55.2 0.2 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 ATG13 PF10033.4 KNZ71985.1 - 2e-24 86.3 0.0 3.5e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 N2227 PF07942.7 KNZ71986.1 - 3.2e-62 209.9 0.0 4e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KNZ71986.1 - 4.6e-06 26.4 0.0 9.1e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ71986.1 - 0.0087 16.5 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ71986.1 - 0.066 13.7 0.0 0.17 12.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ71986.1 - 0.15 12.1 0.0 0.46 10.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Histone PF00125.19 KNZ71987.1 - 4e-30 103.7 0.8 6.7e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNZ71987.1 - 1.4e-05 25.1 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KNZ71987.1 - 0.00067 19.6 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KNZ71987.1 - 0.016 14.9 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KNZ71987.1 - 0.087 12.0 1.0 0.096 11.9 0.7 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Hist_deacetyl PF00850.14 KNZ71988.1 - 1.3e-61 208.5 0.2 2.2e-61 207.8 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Mito_carr PF00153.22 KNZ71989.1 - 1.3e-56 188.2 5.2 9.8e-19 66.8 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF202 PF02656.10 KNZ71990.1 - 2.1e-19 69.5 5.1 2.1e-19 69.5 3.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TrbC PF04956.8 KNZ71990.1 - 4.1 7.4 11.9 1.6 8.7 1.0 2.1 2 0 0 2 2 2 0 TrbC/VIRB2 family RRM_6 PF14259.1 KNZ71991.1 - 3.5e-14 52.5 0.0 3.1e-12 46.2 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KNZ71991.1 - 1.8e-10 40.2 1.2 3.5e-07 29.7 0.1 3.9 4 1 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ71991.1 - 2.7e-05 23.9 0.2 0.47 10.3 0.1 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 KNZ71992.1 - 6.3e-29 100.8 31.7 5.2e-28 97.8 22.0 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ71992.1 - 1.3e-06 27.4 44.8 8.7e-06 24.6 9.7 2.9 1 1 0 2 2 2 2 Major Facilitator Superfamily Pectinesterase PF01095.14 KNZ71993.1 - 1.2e-34 119.3 0.2 1.5e-34 118.9 0.2 1.1 1 0 0 1 1 1 1 Pectinesterase STE2 PF02116.10 KNZ71994.1 - 0.015 14.3 1.4 0.015 14.3 1.0 1.6 2 0 0 2 2 2 0 Fungal pheromone mating factor STE2 GPCR bZIP_1 PF00170.16 KNZ71995.1 - 2.4e-08 33.8 6.5 4.1e-08 33.0 4.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KNZ71995.1 - 0.00027 20.7 10.9 0.00049 19.8 7.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KNZ71995.1 - 0.0078 16.4 3.2 0.014 15.6 2.2 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Suc_Fer-like PF06999.7 KNZ71996.1 - 1.7e-23 83.8 0.0 6.8e-22 78.6 0.0 2.1 2 0 0 2 2 2 2 Sucrase/ferredoxin-like DAO PF01266.19 KNZ71998.1 - 7e-10 38.3 0.1 1.3e-09 37.4 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase TPR_12 PF13424.1 KNZ71999.1 - 1.6e-89 293.9 15.0 2.6e-14 52.9 0.0 9.1 2 2 6 9 9 9 9 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ71999.1 - 2e-72 237.2 0.0 2.6e-08 33.5 0.0 11.9 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ71999.1 - 1.6e-16 60.4 5.7 0.0044 17.6 0.1 6.2 3 2 5 8 8 8 5 Tetratricopeptide repeat Patatin PF01734.17 KNZ71999.1 - 6.1e-15 55.6 0.0 1.2e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_17 PF13431.1 KNZ71999.1 - 3.2e-14 51.8 0.3 2.2 8.6 0.0 10.1 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ71999.1 - 4e-09 35.7 23.8 6.5 6.9 0.1 10.9 11 0 0 11 11 11 1 Tetratricopeptide repeat DUF4404 PF14357.1 KNZ71999.1 - 8.9e-08 32.4 20.9 0.32 11.4 0.1 8.6 3 2 6 9 9 9 3 Domain of unknown function (DUF4404) TPR_7 PF13176.1 KNZ71999.1 - 1.1e-06 27.9 16.8 38 4.4 0.0 9.9 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_4 PF07721.9 KNZ71999.1 - 1.6e-05 24.8 0.1 77 4.1 0.0 8.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ71999.1 - 0.0024 17.3 19.5 26 4.6 0.0 10.1 12 0 0 12 12 11 0 Tetratricopeptide repeat ProSAAS PF07259.7 KNZ71999.1 - 0.018 14.5 6.9 29 4.1 0.0 6.2 3 2 3 7 7 7 0 ProSAAS precursor DUF4648 PF15505.1 KNZ71999.1 - 0.12 12.5 1.2 2.8 8.1 0.0 3.3 2 1 1 4 4 3 0 Domain of unknown function (DUF4648) CTD_bind PF04818.8 KNZ71999.1 - 2.7 8.3 8.2 1.8e+02 2.4 0.0 6.2 6 2 3 9 9 8 0 RNA polymerase II-binding domain. Zn_Tnp_IS1595 PF12760.2 KNZ72000.1 - 0.042 13.6 9.3 0.25 11.1 6.5 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 KNZ72000.1 - 0.07 12.6 0.6 0.22 11.0 0.4 1.8 1 0 0 1 1 1 0 zinc-ribbon domain PBP_sp32 PF07222.7 KNZ72000.1 - 0.31 10.1 1.7 0.34 10.0 1.2 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 zf-FPG_IleRS PF06827.9 KNZ72000.1 - 0.83 9.3 4.2 0.46 10.1 0.9 2.1 2 1 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF3039 PF11238.3 KNZ72000.1 - 0.89 9.0 5.1 0.13 11.7 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3039) PIF1 PF05970.9 KNZ72001.1 - 3.4e-26 92.0 0.0 4.5e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ72001.1 - 0.049 13.2 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KNZ72001.1 - 0.056 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 KNZ72001.1 - 0.07 13.3 0.0 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 KNZ72001.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF2791 PF10923.3 KNZ72001.1 - 0.14 10.7 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) REF PF05755.7 KNZ72001.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Y_phosphatase PF00102.22 KNZ72001.1 - 0.27 10.5 1.1 0.93 8.7 0.1 1.9 1 1 1 2 2 2 0 Protein-tyrosine phosphatase SH3_1 PF00018.23 KNZ72003.1 - 4.2e-13 48.4 0.0 6.2e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KNZ72003.1 - 8.9e-12 44.4 0.0 1.7e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KNZ72003.1 - 1.9e-09 36.8 0.0 3.1e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Sporozoite_P67 PF05642.6 KNZ72003.1 - 0.035 11.9 6.1 0.042 11.7 4.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_LMP1 PF05297.6 KNZ72003.1 - 0.81 8.5 3.2 1.7 7.4 2.2 1.6 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Sugar_tr PF00083.19 KNZ72005.1 - 8.6e-101 337.7 13.8 1.5e-100 336.9 9.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ72005.1 - 5.8e-28 97.6 29.9 1e-26 93.5 16.1 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily AMP-binding PF00501.23 KNZ72006.1 - 1.2e-76 257.8 0.0 1.5e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF202 PF02656.10 KNZ72007.1 - 0.00022 21.3 4.3 0.00089 19.4 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF981 PF06168.6 KNZ72007.1 - 0.034 13.9 4.8 1.9 8.2 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF981) DUF3040 PF11239.3 KNZ72007.1 - 0.11 12.5 9.1 3.7 7.6 6.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2975 PF11188.3 KNZ72007.1 - 0.19 11.4 3.4 0.23 11.1 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) VMA21 PF09446.5 KNZ72007.1 - 0.27 11.1 5.1 0.31 11.0 3.5 1.3 1 1 0 1 1 1 0 VMA21-like domain CRPA PF05745.6 KNZ72007.1 - 2.3 7.9 5.7 4.5 7.0 3.9 1.5 1 1 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Gram_pos_anchor PF00746.16 KNZ72007.1 - 6.8 6.6 8.3 16 5.4 0.8 2.8 2 0 0 2 2 2 0 Gram positive anchor Pectinesterase PF01095.14 KNZ72009.1 - 6.6e-39 133.2 6.3 8.3e-39 132.9 4.3 1.0 1 0 0 1 1 1 1 Pectinesterase DER1 PF04511.10 KNZ72010.1 - 2.6e-25 89.1 5.2 1.9e-16 60.1 0.1 2.0 1 1 1 2 2 2 2 Der1-like family Rhomboid PF01694.17 KNZ72010.1 - 0.12 12.4 5.2 2 8.4 3.6 2.2 1 1 0 1 1 1 0 Rhomboid family Na_H_Exchanger PF00999.16 KNZ72011.1 - 1.4e-54 185.1 42.1 2e-54 184.6 29.2 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.16 KNZ72012.1 - 1.5e-61 208.0 49.0 2.2e-61 207.4 34.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_hydro_35 PF01301.14 KNZ72014.1 - 5.5e-73 246.1 0.0 7.9e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 KNZ72014.1 - 3.5e-48 162.4 4.6 4.2e-26 91.3 0.3 3.0 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 KNZ72014.1 - 5.1e-35 120.4 1.4 9.1e-35 119.6 0.9 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 KNZ72014.1 - 2.5e-19 68.4 0.6 5.4e-19 67.3 0.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Amidohydro_2 PF04909.9 KNZ72014.1 - 0.02 14.4 0.1 0.085 12.4 0.0 1.9 2 0 0 2 2 2 0 Amidohydrolase Glyco_hydro_42 PF02449.10 KNZ72014.1 - 0.032 13.3 0.2 0.21 10.6 0.1 2.0 1 1 0 1 1 1 0 Beta-galactosidase COX4 PF02936.9 KNZ72015.1 - 5.3e-34 116.9 0.1 6.8e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Unstab_antitox PF09720.5 KNZ72015.1 - 0.03 14.0 1.4 0.28 10.8 0.0 2.3 2 0 0 2 2 2 0 Putative addiction module component Ank_2 PF12796.2 KNZ72016.1 - 1.2e-06 28.7 0.3 3.7e-05 23.9 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNZ72016.1 - 6e-06 26.6 0.2 3.2e-05 24.2 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KNZ72016.1 - 0.00051 20.2 0.1 0.056 13.7 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ72016.1 - 0.00063 19.7 0.1 2.9 8.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 KNZ72016.1 - 0.028 14.2 0.3 0.76 9.7 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.2 KNZ72017.1 - 2.8e-19 69.2 0.3 8.3e-10 38.8 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNZ72017.1 - 2.5e-15 56.4 1.9 6.6e-06 26.4 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ72017.1 - 3.1e-14 51.6 3.1 0.069 13.4 0.0 6.6 6 1 1 7 7 7 4 Ankyrin repeat Ank PF00023.25 KNZ72017.1 - 3e-12 45.6 3.0 0.018 14.8 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KNZ72017.1 - 7.1e-10 38.8 2.4 0.015 15.5 0.3 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) TPR_10 PF13374.1 KNZ72020.1 - 3.6e-15 55.3 1.4 8e-07 28.7 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ72020.1 - 8.8e-09 35.1 0.4 1.1e-08 34.8 0.3 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ72020.1 - 0.0004 20.3 0.1 0.075 13.2 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF4404 PF14357.1 KNZ72020.1 - 0.0052 17.1 0.3 0.0093 16.3 0.0 1.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4404) Carbpep_Y_N PF05388.6 KNZ72020.1 - 0.095 12.8 0.0 9.7 6.3 0.0 2.0 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide Steroid_dh PF02544.11 KNZ72021.1 - 1.6e-25 89.6 1.2 6.9e-16 58.3 0.0 2.6 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KNZ72021.1 - 2.2e-05 23.9 0.1 4.3e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) GMC_oxred_N PF00732.14 KNZ72022.1 - 1.8e-19 70.0 0.7 1e-18 67.5 0.1 2.0 2 0 0 2 2 2 1 GMC oxidoreductase zf-RING_2 PF13639.1 KNZ72022.1 - 1.8e-09 37.2 7.9 4e-09 36.1 1.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KNZ72022.1 - 4.5e-05 23.3 1.8 4.5e-05 23.3 1.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KNZ72022.1 - 4.8e-05 23.3 0.6 4.8e-05 23.3 0.4 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KNZ72022.1 - 0.00016 21.2 1.0 0.00016 21.2 0.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ72022.1 - 0.00039 20.0 0.5 0.00039 20.0 0.3 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KNZ72022.1 - 0.001 18.8 0.2 0.002 17.9 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KNZ72022.1 - 0.0012 18.4 0.7 0.0012 18.4 0.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KNZ72022.1 - 0.45 10.5 2.0 0.6 10.1 0.1 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain DUF2890 PF11081.3 KNZ72022.1 - 0.45 10.5 13.0 0.16 11.9 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) DUF605 PF04652.11 KNZ72022.1 - 9 5.5 42.3 5.3 6.3 15.0 2.1 2 0 0 2 2 2 0 Vta1 like Nop PF01798.13 KNZ72023.1 - 1.6e-58 196.2 0.0 2.8e-58 195.4 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KNZ72023.1 - 6.2e-26 89.9 0.3 4e-25 87.3 0.0 2.4 3 0 0 3 3 3 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KNZ72023.1 - 1.7e-22 79.3 0.5 1.7e-22 79.3 0.3 2.1 2 0 0 2 2 2 1 NOP5NT (NUC127) domain FRG1 PF06229.7 KNZ72023.1 - 0.0021 17.5 3.9 0.0034 16.8 2.7 1.4 1 0 0 1 1 1 1 FRG1-like family DUF2151 PF10221.4 KNZ72023.1 - 1.4 7.0 8.2 2.1 6.3 5.7 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator UPF0223 PF05256.7 KNZ72024.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0223) PIF1 PF05970.9 KNZ72025.1 - 1.4e-49 168.9 0.0 1.8e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ72025.1 - 0.00067 19.2 0.0 0.00091 18.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KNZ72025.1 - 0.014 14.8 0.2 0.035 13.6 0.1 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KNZ72025.1 - 0.026 14.5 0.0 0.046 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.10 KNZ72025.1 - 0.027 14.3 0.0 0.06 13.1 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KNZ72025.1 - 0.082 13.0 0.1 0.42 10.7 0.1 2.1 1 1 0 1 1 1 0 RNA helicase IBN_N PF03810.14 KNZ72027.1 - 1.3e-08 34.6 0.3 3.1e-07 30.1 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KNZ72027.1 - 0.0056 16.5 1.2 0.054 13.4 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein DUF1446 PF07287.6 KNZ72027.1 - 0.043 12.2 0.0 0.12 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1446) HEAT PF02985.17 KNZ72027.1 - 0.086 12.9 0.0 1.3 9.3 0.1 3.2 2 0 0 2 2 2 0 HEAT repeat Actin PF00022.14 KNZ72028.1 - 1.7e-80 270.4 0.0 2e-80 270.1 0.0 1.0 1 0 0 1 1 1 1 Actin NRDE PF05742.7 KNZ72029.1 - 3.1e-29 102.1 0.0 5.8e-29 101.2 0.0 1.3 1 1 0 1 1 1 1 NRDE protein Zn_clus PF00172.13 KNZ72030.1 - 1.1e-08 34.8 7.2 2.5e-08 33.7 5.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSS PF03034.10 KNZ72031.1 - 9.7e-99 330.2 9.2 1.2e-98 329.9 6.4 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase MFS_1 PF07690.11 KNZ72033.1 - 5.5e-26 91.1 22.8 5.5e-26 91.1 15.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily YTH PF04146.10 KNZ72034.1 - 6.3e-51 171.6 0.0 1e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 KNZ72034.1 - 0.00012 21.6 0.0 0.001 18.6 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ72034.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_8 PF13450.1 KNZ72035.1 - 7e-15 54.8 0.0 3.9e-14 52.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KNZ72035.1 - 1.3e-11 44.2 0.3 4.5e-05 22.6 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KNZ72035.1 - 4e-05 23.7 0.0 0.00049 20.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KNZ72035.1 - 0.0021 17.0 0.5 0.0043 16.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KNZ72035.1 - 0.0053 16.5 0.0 0.18 11.5 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 KNZ72035.1 - 0.018 14.1 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KNZ72035.1 - 0.073 11.5 0.0 0.36 9.2 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Mem_trans PF03547.13 KNZ72039.1 - 2.4e-33 115.0 3.1 2.9e-33 114.7 2.2 1.1 1 0 0 1 1 1 1 Membrane transport protein Melibiase PF02065.13 KNZ72043.1 - 1e-21 77.1 1.1 1.6e-17 63.2 0.0 2.9 1 1 0 2 2 2 2 Melibiase PH PF00169.24 KNZ72044.1 - 0.033 14.3 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 PH domain Cytochrom_B562 PF07361.6 KNZ72044.1 - 0.62 10.5 5.2 0.26 11.7 0.1 2.9 2 1 1 3 3 3 0 Cytochrome b562 2OG-FeII_Oxy_2 PF13532.1 KNZ72045.1 - 4.3e-16 59.3 0.0 9.1e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C2HC5 PF06221.8 KNZ72045.1 - 1.5 8.6 5.6 0.2 11.4 1.0 1.7 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type ATP-synt_DE_N PF02823.11 KNZ72046.1 - 1.3e-19 69.6 0.2 1.9e-19 69.1 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain GCS PF03074.11 KNZ72047.1 - 9.3e-168 558.0 0.2 1.2e-167 557.7 0.2 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase S1 PF00575.18 KNZ72047.1 - 0.1 12.7 0.1 0.65 10.1 0.0 2.4 3 0 0 3 3 3 0 S1 RNA binding domain Nic96 PF04097.9 KNZ72050.1 - 1e-29 103.1 1.7 1.3e-29 102.8 1.2 1.0 1 0 0 1 1 1 1 Nup93/Nic96 DUF2496 PF10689.4 KNZ72051.1 - 1.2 8.7 4.9 5 6.7 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2496) WD40 PF00400.27 KNZ72054.1 - 5e-09 35.6 0.9 0.0022 17.8 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.1 KNZ72054.1 - 3.3e-05 23.4 0.1 0.011 15.1 0.0 2.9 1 1 1 2 2 2 2 PQQ-like domain BBS1 PF14779.1 KNZ72054.1 - 0.00013 21.0 0.1 0.14 11.0 0.0 3.3 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 1 PQQ_3 PF13570.1 KNZ72054.1 - 0.00044 20.4 0.2 2.6 8.4 0.0 4.6 5 0 0 5 5 5 1 PQQ-like domain BBS2_Mid PF14783.1 KNZ72054.1 - 0.00095 18.9 0.4 4.9 6.9 0.0 3.7 3 2 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.16 KNZ72054.1 - 0.022 14.3 0.2 2 8.1 0.1 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat RVP_2 PF08284.6 KNZ72055.1 - 0.00041 20.2 0.1 0.00058 19.8 0.1 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 KNZ72055.1 - 0.13 11.8 0.0 16 5.1 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease rve PF00665.21 KNZ72056.1 - 8.6e-07 29.0 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KNZ72056.1 - 0.0091 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve PF00665.21 KNZ72057.1 - 1.5e-08 34.7 0.0 2.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KNZ72057.1 - 0.049 13.1 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain YchF-GTPase_C PF06071.8 KNZ72058.1 - 3.6e-36 122.8 0.0 9.6e-36 121.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KNZ72058.1 - 9.5e-15 54.5 0.0 4.5e-14 52.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KNZ72058.1 - 7.8e-06 25.2 0.0 1.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 KNZ72058.1 - 0.01 16.6 0.0 0.044 14.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KNZ72058.1 - 0.015 15.5 0.1 0.81 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KNZ72058.1 - 0.035 12.8 0.2 0.38 9.4 0.0 2.1 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 KNZ72058.1 - 0.12 12.1 0.2 0.6 9.9 0.1 2.1 2 1 1 3 3 3 0 Dynamin family SRRM_C PF15230.1 KNZ72059.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus Nop14 PF04147.7 KNZ72060.1 - 9.7 3.9 18.2 15 3.3 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family MMtag PF10159.4 KNZ72062.1 - 3.4e-30 103.9 2.6 3.4e-30 103.9 1.8 3.4 3 1 1 4 4 4 1 Kinase phosphorylation protein Rrp15p PF07890.7 KNZ72062.1 - 0.0075 16.3 6.6 0.0075 16.3 4.6 2.3 3 1 0 3 3 3 1 Rrp15p IncA PF04156.9 KNZ72062.1 - 0.15 11.6 7.1 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 IncA protein F-box PF00646.28 KNZ72063.1 - 3e-07 29.9 9.6 5.5e-05 22.7 0.1 3.3 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.2 KNZ72063.1 - 0.0015 18.1 2.0 0.049 13.3 0.2 2.9 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KNZ72063.1 - 0.047 13.4 0.4 0.38 10.4 0.0 2.4 2 0 0 2 2 2 0 F-box-like domain MARVEL PF01284.18 KNZ72065.1 - 1.2e-07 31.6 7.9 4e-07 29.9 3.4 2.3 1 1 1 2 2 2 2 Membrane-associating domain Pro_isomerase PF00160.16 KNZ72067.1 - 7.1e-22 78.2 0.0 1.4e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD rve PF00665.21 KNZ72067.1 - 2.3e-09 37.3 0.0 4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Abhydrolase_5 PF12695.2 KNZ72068.1 - 4.9e-11 42.5 0.0 7.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ72068.1 - 6.8e-07 29.3 0.0 1.6e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PhoPQ_related PF10142.4 KNZ72068.1 - 0.00015 20.3 0.0 0.00087 17.8 0.0 2.0 1 1 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Peptidase_S9 PF00326.16 KNZ72068.1 - 0.0075 15.5 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DEAD PF00270.24 KNZ72069.1 - 3.8e-48 163.1 0.0 1.1e-46 158.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ72069.1 - 8.1e-28 96.1 0.0 1.8e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ72069.1 - 4.9e-07 29.7 0.0 2.2e-06 27.6 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KNZ72069.1 - 0.0012 18.5 0.0 0.078 12.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF1253 PF06862.7 KNZ72069.1 - 0.012 13.9 0.0 0.14 10.5 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 KNZ72069.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain DUF2443 PF10398.4 KNZ72069.1 - 0.048 13.4 0.2 0.092 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) AAA PF00004.24 KNZ72069.1 - 0.14 12.3 0.1 16 5.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RAM PF15320.1 KNZ72069.1 - 0.25 11.6 5.6 0.6 10.4 3.9 1.6 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Ras PF00071.17 KNZ72070.1 - 5.9e-40 136.3 0.0 8.3e-40 135.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ72070.1 - 5.9e-16 59.0 0.0 1.2e-15 57.9 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KNZ72070.1 - 0.0001 22.2 0.0 0.00015 21.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KNZ72070.1 - 0.00039 19.9 0.0 0.15 11.5 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.16 KNZ72070.1 - 0.01 15.0 0.0 0.089 12.0 0.0 2.0 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_10 PF12846.2 KNZ72070.1 - 0.029 13.8 0.1 0.14 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA-like domain DUF2075 PF09848.4 KNZ72070.1 - 0.035 13.0 0.1 0.14 11.0 0.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 KNZ72070.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.7 2 1 0 2 2 2 0 AAA ATPase domain Methyltransf_23 PF13489.1 KNZ72072.1 - 2.6e-16 59.7 0.0 3.4e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ72072.1 - 1.4e-14 54.3 0.0 2.7e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ72072.1 - 1.9e-14 53.5 0.0 5.1e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ72072.1 - 1.7e-13 50.8 0.0 1.1e-12 48.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ72072.1 - 6.3e-13 49.2 0.0 3.3e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ72072.1 - 8.5e-09 35.7 0.0 4.9e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ72072.1 - 8.8e-07 28.9 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KNZ72072.1 - 2.1e-05 23.6 0.0 5.7e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KNZ72072.1 - 9.1e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 KNZ72072.1 - 0.00021 20.7 0.0 0.00053 19.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KNZ72072.1 - 0.00025 20.2 0.0 0.0026 16.9 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 KNZ72072.1 - 0.00035 19.8 0.0 0.015 14.6 0.0 2.2 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain PrmA PF06325.8 KNZ72072.1 - 0.0026 16.9 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 KNZ72072.1 - 0.0069 15.8 0.0 0.014 14.7 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.4 KNZ72072.1 - 0.035 13.5 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_29 PF03141.11 KNZ72072.1 - 0.04 12.2 0.0 0.29 9.4 0.0 1.9 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.15 KNZ72072.1 - 0.051 12.6 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 KNZ72072.1 - 0.075 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase PCMT PF01135.14 KNZ72072.1 - 0.079 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RRM_1 PF00076.17 KNZ72073.1 - 1.6e-14 53.2 0.1 2.5e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ72073.1 - 6.3e-11 42.1 0.0 1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ72073.1 - 0.00067 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyoxalase_2 PF12681.2 KNZ72073.1 - 0.022 15.3 0.0 0.048 14.2 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain Proteasome PF00227.21 KNZ72074.1 - 8.8e-28 96.8 0.1 1.1e-27 96.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit HSV_VP16_C PF12149.3 KNZ72074.1 - 0.035 13.7 0.5 0.035 13.7 0.3 1.9 2 0 0 2 2 2 0 Herpes simplex virus virion protein 16 C terminal PI3Ka PF00613.15 KNZ72075.1 - 2.6e-53 179.9 0.1 3.9e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 KNZ72075.1 - 1.4e-40 138.3 0.0 2.6e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3_PI4_kinase PF00454.22 KNZ72075.1 - 3.5e-40 137.9 0.0 7.2e-39 133.6 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase C2 PF00168.25 KNZ72075.1 - 0.0012 18.6 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain Vps26 PF03643.10 KNZ72077.1 - 3.4e-10 39.1 0.0 8.1e-10 37.9 0.0 1.5 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 26 gag-asp_proteas PF13975.1 KNZ72080.1 - 0.0018 18.0 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ72080.1 - 0.0031 17.9 0.0 0.011 16.2 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Vps26 PF03643.10 KNZ72081.1 - 6.7e-38 130.0 0.2 1.8e-29 102.3 0.0 2.1 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 UBN2_2 PF14227.1 KNZ72082.1 - 0.022 14.3 0.0 0.073 12.6 0.0 1.8 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type RNase_H PF00075.19 KNZ72083.1 - 4.6e-06 27.0 0.1 4.6e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 RNase H UBN2_2 PF14227.1 KNZ72084.1 - 8.8e-06 25.2 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KNZ72084.1 - 0.0012 18.4 1.3 0.0012 18.4 0.9 2.3 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ72084.1 - 0.0019 18.0 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4285 PF14113.1 KNZ72084.1 - 0.087 12.8 0.6 5.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4285) BNIP2 PF12496.3 KNZ72085.1 - 0.0014 18.7 1.3 0.0019 18.3 0.9 1.1 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Vps26 PF03643.10 KNZ72086.1 - 3e-119 396.8 3.0 3.6e-119 396.6 2.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KNZ72086.1 - 0.0076 16.0 1.9 0.39 10.5 0.1 3.2 2 2 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Complex1_51K PF01512.12 KNZ72087.1 - 1.7e-48 164.1 0.0 2.8e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KNZ72087.1 - 1.8e-19 68.6 0.3 1.8e-19 68.6 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KNZ72087.1 - 1.2e-08 34.7 0.0 4.9e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 SLBB domain FAD-oxidase_C PF02913.14 KNZ72089.1 - 2.2e-55 187.6 0.0 3.9e-55 186.8 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KNZ72089.1 - 4.7e-30 103.8 0.0 9e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain eIF3_N PF09440.5 KNZ72090.1 - 1.3e-42 145.0 4.0 2.6e-41 140.9 2.4 2.4 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KNZ72090.1 - 2.3e-08 34.2 0.1 8.2e-08 32.5 0.0 2.0 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 KNZ72090.1 - 0.0098 15.6 0.0 0.035 13.8 0.0 1.8 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 Cpn60_TCP1 PF00118.19 KNZ72091.1 - 2.2e-159 531.1 2.0 2.6e-159 530.9 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L4 PF00573.17 KNZ72092.1 - 8.3e-44 149.2 1.8 1.5e-43 148.4 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KNZ72092.1 - 1.4e-29 101.7 4.8 1.8e-29 101.4 1.0 2.4 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain zf-ZPR1 PF03367.8 KNZ72095.1 - 6e-97 321.3 0.0 5.8e-49 165.3 0.0 3.1 2 1 1 3 3 3 3 ZPR1 zinc-finger domain HypA PF01155.14 KNZ72095.1 - 0.015 15.0 0.3 0.62 9.7 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 KNZ72095.1 - 0.039 13.7 1.4 1.6 8.5 0.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 KNZ72095.1 - 0.1 11.8 4.8 5.6 6.3 1.1 3.0 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KNZ72095.1 - 0.12 11.8 7.2 1.3 8.5 0.0 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KNZ72095.1 - 0.2 11.6 4.2 2.3 8.2 0.1 3.4 3 0 0 3 3 3 0 Zinc ribbon domain Ribosomal_L37e PF01907.14 KNZ72095.1 - 0.55 10.0 3.9 1.8 8.4 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein L37e OrfB_Zn_ribbon PF07282.6 KNZ72095.1 - 0.66 9.6 2.8 34 4.1 0.0 3.2 3 0 0 3 3 3 0 Putative transposase DNA-binding domain UPF0547 PF10571.4 KNZ72095.1 - 4.6 7.0 6.5 26 4.6 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.1 KNZ72095.1 - 6.7 6.4 8.2 0.92 9.2 0.1 3.1 3 0 0 3 3 3 0 Nudix N-terminal ABC_membrane PF00664.18 KNZ72096.1 - 2.5e-34 118.9 11.7 3.2e-34 118.6 8.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KNZ72096.1 - 2.1e-08 34.5 0.0 7.3e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 KNZ72096.1 - 0.00017 20.9 0.0 0.0002 20.6 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KNZ72096.1 - 0.00034 20.6 0.2 0.00069 19.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KNZ72096.1 - 0.055 13.3 0.4 0.51 10.2 0.3 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Sec34 PF04136.10 KNZ72097.1 - 6.6e-27 94.1 0.1 1.5e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Sec34-like family zf-H2C2_2 PF13465.1 KNZ72098.1 - 4.8e-11 42.3 6.5 5.1e-07 29.6 0.2 4.2 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KNZ72098.1 - 4.5e-09 36.1 12.0 0.00036 20.7 2.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ72098.1 - 1.3e-06 28.3 11.6 0.00012 22.1 2.6 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KNZ72098.1 - 0.001 19.1 2.6 0.0016 18.5 0.5 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Zn_clus PF00172.13 KNZ72098.1 - 0.014 15.3 12.2 0.03 14.2 8.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_Tnp_IS1 PF03811.8 KNZ72098.1 - 0.034 13.6 7.5 0.13 11.7 5.2 2.1 1 0 0 1 1 1 0 InsA N-terminal domain zf-C2H2_2 PF12756.2 KNZ72098.1 - 0.089 12.9 5.1 0.48 10.5 0.3 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Rad50_zn_hook PF04423.9 KNZ72098.1 - 0.16 11.4 1.5 6.5 6.3 0.1 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2_6 PF13912.1 KNZ72098.1 - 0.45 10.4 7.9 1.4 8.8 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger UBN2_2 PF14227.1 KNZ72099.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type V_ATPase_I PF01496.14 KNZ72099.1 - 0.031 12.1 0.0 0.039 11.8 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UBN2_3 PF14244.1 KNZ72099.1 - 0.042 13.4 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ72099.1 - 0.064 13.0 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF572 PF04502.8 KNZ72101.1 - 7.2e-56 189.7 0.7 1.2e-55 188.9 0.5 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF572) Myosin_tail_1 PF01576.14 KNZ72101.1 - 0.0092 13.7 5.1 0.011 13.4 3.5 1.2 1 0 0 1 1 1 1 Myosin tail DUF3994 PF13159.1 KNZ72101.1 - 0.077 13.2 1.5 0.084 13.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) TMPIT PF07851.8 KNZ72101.1 - 1.4 7.9 2.9 0.71 8.8 0.5 1.5 1 1 0 1 1 1 0 TMPIT-like protein ARID PF01388.16 KNZ72102.1 - 6.9e-10 38.6 0.0 2.5e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain SNARE_assoc PF09335.6 KNZ72103.1 - 3e-12 46.8 6.9 6.9e-12 45.6 4.0 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein Exo_endo_phos PF03372.18 KNZ72104.1 - 1.1e-09 38.6 0.5 3.5e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family NAPRTase PF04095.11 KNZ72105.1 - 1.9e-60 204.1 0.1 3.2e-60 203.4 0.1 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family RNase_PH PF01138.16 KNZ72106.1 - 7.3e-35 120.1 0.3 1.5e-34 119.1 0.1 1.7 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KNZ72106.1 - 6.4e-05 22.8 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Methyltransf_4 PF02390.12 KNZ72107.1 - 4.2e-42 143.4 0.0 5e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Citrate_synt PF00285.16 KNZ72108.1 - 2.6e-77 259.9 0.0 8.8e-61 205.5 0.0 2.1 1 1 1 2 2 2 2 Citrate synthase Eclosion PF04736.7 KNZ72108.1 - 0.18 11.2 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone PLDc_2 PF13091.1 KNZ72109.1 - 2.7e-11 43.2 0.0 3.6e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KNZ72109.1 - 5.1e-09 35.6 0.1 0.00039 20.1 0.1 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif Actin PF00022.14 KNZ72110.1 - 4.6e-89 298.5 0.0 6.3e-89 298.1 0.0 1.1 1 0 0 1 1 1 1 Actin UbiA PF01040.13 KNZ72112.1 - 5.8e-29 101.0 24.3 8.7e-29 100.5 16.8 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Homeobox PF00046.24 KNZ72113.1 - 1.9e-18 65.8 5.7 4.7e-18 64.5 3.9 1.7 1 0 0 1 1 1 1 Homeobox domain zf-Tim10_DDP PF02953.10 KNZ72114.1 - 1e-22 79.1 1.5 1.2e-22 78.9 1.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FANCI_S3 PF14677.1 KNZ72114.1 - 0.015 14.7 0.1 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 FANCI solenoid 3 TIL PF01826.12 KNZ72114.1 - 0.062 13.4 1.0 0.09 12.9 0.7 1.2 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain DnaJ PF00226.26 KNZ72115.1 - 4.2e-22 77.6 0.4 1e-21 76.4 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 KNZ72115.1 - 4.4e-10 39.3 0.4 1.1e-09 38.1 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KNZ72115.1 - 5.9e-09 35.8 0.5 1.4e-08 34.6 0.4 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KNZ72115.1 - 0.0071 16.4 0.1 0.018 15.1 0.1 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.6 KNZ72115.1 - 0.072 12.7 0.4 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Prp18 PF02840.10 KNZ72116.1 - 3.7e-58 195.4 2.6 5.2e-58 195.0 0.0 2.2 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 KNZ72116.1 - 1.2e-12 46.8 4.3 2.3e-12 45.9 3.0 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like DUF4407 PF14362.1 KNZ72116.1 - 4.7 6.0 7.8 0.24 10.3 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) COX6B PF02297.12 KNZ72117.1 - 4.1e-20 71.5 6.2 4.6e-20 71.4 4.3 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 KNZ72117.1 - 0.00094 19.0 2.8 0.0016 18.2 2.0 1.5 1 0 0 1 1 1 1 CHCH domain UPF0203 PF05254.7 KNZ72117.1 - 1.9 8.3 7.7 5.4 6.9 1.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Oxidored_molyb PF00174.14 KNZ72118.1 - 4.5e-54 182.3 0.0 6.4e-54 181.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KNZ72118.1 - 1.6e-19 69.8 0.9 3.2e-19 68.8 0.6 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.15 KNZ72118.1 - 0.036 13.8 1.0 0.16 11.8 0.7 2.1 1 0 0 1 1 1 0 BNR/Asp-box repeat Gmad2 PF10648.4 KNZ72118.1 - 0.11 12.7 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination DUF1748 PF08520.5 KNZ72119.1 - 2.1e-23 81.7 0.0 2.4e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Glyco_hydro_18 PF00704.23 KNZ72120.1 - 1.1e-14 54.6 2.6 1.7e-14 54.0 1.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.9 KNZ72120.1 - 5e-10 38.7 7.4 1.6e-09 37.1 5.1 2.0 1 0 0 1 1 1 1 Carbohydrate binding domain AKAP2_C PF15304.1 KNZ72120.1 - 0.1 12.1 1.7 0.15 11.6 1.2 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Mucin PF01456.12 KNZ72120.1 - 0.27 11.0 22.8 0.54 10.0 15.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Fungal_trans PF04082.13 KNZ72121.1 - 1.4e-11 43.8 0.0 2.2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Adaptin_N PF01602.15 KNZ72122.1 - 1.4e-121 406.4 0.6 2.1e-121 405.8 0.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KNZ72122.1 - 5.1e-07 29.8 0.9 0.0088 16.2 0.0 4.0 3 1 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 KNZ72122.1 - 0.00031 21.1 0.3 3.5 8.2 0.0 4.7 4 1 0 4 4 4 1 HEAT-like repeat HEAT PF02985.17 KNZ72122.1 - 0.011 15.7 5.0 5 7.4 0.0 5.9 6 0 0 6 6 6 0 HEAT repeat Myc_N PF01056.13 KNZ72122.1 - 0.092 11.9 2.6 0.19 10.8 1.8 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 KNZ72122.1 - 6.7 5.0 15.2 10 4.4 10.5 1.2 1 0 0 1 1 1 0 Daxx Family RVT_2 PF07727.9 KNZ72123.1 - 0.00019 20.4 0.0 0.00045 19.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Frag1 PF10277.4 KNZ72124.1 - 1e-40 139.5 10.8 1e-40 139.5 7.5 2.3 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 KNZ72124.1 - 4.9e-05 23.3 0.0 9.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2417 PF10329.4 KNZ72124.1 - 1.6 8.0 5.4 1 8.6 0.4 2.4 2 0 0 2 2 2 0 Region of unknown function (DUF2417) cobW PF02492.14 KNZ72125.1 - 3e-37 127.8 0.0 3.8e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KNZ72125.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.9 KNZ72125.1 - 0.0032 17.1 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Pox_A32 PF04665.7 KNZ72125.1 - 0.12 11.6 0.0 0.34 10.1 0.0 1.6 2 0 0 2 2 2 0 Poxvirus A32 protein DUF1574 PF07611.6 KNZ72125.1 - 0.14 10.9 0.0 0.29 9.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1574) DnaJ PF00226.26 KNZ72126.1 - 1.3e-17 63.3 0.2 3.8e-17 61.7 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain Serinc PF03348.10 KNZ72128.1 - 3e-139 464.4 7.3 3.7e-139 464.1 5.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) OTOS PF15182.1 KNZ72128.1 - 0.12 12.0 0.2 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Otospiralin Acetyltransf_13 PF13880.1 KNZ72129.1 - 2.3e-12 46.4 0.0 4.2e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 KNZ72129.1 - 3.7e-08 32.7 0.2 6.4e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 KNZ72129.1 - 0.018 15.0 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KNZ72129.1 - 0.076 13.1 0.0 0.14 12.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Nudix_N_2 PF14803.1 KNZ72129.1 - 0.36 10.5 2.8 0.68 9.6 0.8 2.1 2 0 0 2 2 2 0 Nudix N-terminal Rad51 PF08423.6 KNZ72130.1 - 6.8e-08 31.7 0.0 1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 KNZ72130.1 - 8.5e-06 25.0 0.1 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KNZ72130.1 - 0.00035 19.7 0.1 0.0006 19.0 0.0 1.7 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.1 KNZ72130.1 - 0.00041 19.8 0.1 0.00093 18.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KNZ72130.1 - 0.0035 17.2 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain CobU PF02283.11 KNZ72130.1 - 0.0099 15.2 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_22 PF13401.1 KNZ72130.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KNZ72130.1 - 0.026 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 KNZ72130.1 - 0.091 11.6 0.1 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 KNZ72130.1 - 0.095 12.1 0.0 0.3 10.5 0.0 2.0 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KNZ72130.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Asp_protease_2 PF13650.1 KNZ72131.1 - 0.05 14.1 0.0 0.12 12.9 0.0 1.6 2 0 0 2 2 2 0 Aspartyl protease DUF2202 PF09968.4 KNZ72134.1 - 0.0079 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein domain (DUF2202) DUF1356 PF07092.7 KNZ72135.1 - 0.0071 15.5 0.8 0.0094 15.1 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) DnaJ_CXXCXGXG PF00684.14 KNZ72135.1 - 1 9.4 11.1 7.7 6.6 3.8 2.3 1 1 1 2 2 2 0 DnaJ central domain eIF3g PF12353.3 KNZ72135.1 - 1.1 9.2 5.8 0.28 11.1 0.3 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Cytochrome_C554 PF13435.1 KNZ72135.1 - 1.2 9.2 10.7 5.8 6.9 7.5 1.8 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrom_c3_2 PF14537.1 KNZ72135.1 - 1.9 8.9 11.2 1 9.7 2.8 2.2 1 1 1 2 2 2 0 Cytochrome c3 Cytochrome_CBB3 PF13442.1 KNZ72135.1 - 2.2 8.5 4.7 0.36 11.0 0.4 1.9 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_C7 PF14522.1 KNZ72135.1 - 4.9 6.8 9.3 0.22 11.2 1.7 1.8 1 1 1 2 2 2 0 Cytochrome c7 gag-asp_proteas PF13975.1 KNZ72139.1 - 0.023 14.5 0.0 0.053 13.3 0.0 1.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ72139.1 - 0.025 15.0 0.0 0.043 14.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Glyoxalase_4 PF13669.1 KNZ72140.1 - 0.035 14.1 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily rve PF00665.21 KNZ72141.1 - 2e-07 31.1 0.0 4.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KNZ72141.1 - 0.059 12.8 0.1 0.31 10.6 0.0 2.3 2 1 1 3 3 3 0 Integrase core domain Mut7-C PF01927.11 KNZ72141.1 - 1.7 8.6 4.7 0.63 9.9 0.6 2.1 3 0 0 3 3 3 0 Mut7-C RNAse domain DHDPS PF00701.17 KNZ72144.1 - 6.5e-45 152.9 0.0 8.4e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 KNZ72144.1 - 0.0074 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase IstB_IS21_ATP PF08483.6 KNZ72144.1 - 0.16 11.7 0.1 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding N-terminal Dynamin_N PF00350.18 KNZ72145.1 - 3.2e-42 144.2 0.0 8.4e-42 142.8 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KNZ72145.1 - 3.9e-08 32.4 0.0 1.7e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KNZ72145.1 - 0.00089 19.2 0.0 0.003 17.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KNZ72145.1 - 0.0031 17.9 0.0 0.0093 16.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 KNZ72145.1 - 0.041 13.8 0.4 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Spectrin PF00435.16 KNZ72145.1 - 0.081 13.2 2.2 0.24 11.6 0.3 2.6 2 0 0 2 2 2 0 Spectrin repeat FeoB_N PF02421.13 KNZ72145.1 - 0.11 11.7 0.1 8.5 5.6 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B SCP2 PF02036.12 KNZ72146.1 - 1.9e-25 89.1 1.4 2.2e-25 88.9 1.0 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KNZ72146.1 - 1.1e-05 25.4 1.7 1.4e-05 25.0 1.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal CelD_N PF02927.9 KNZ72146.1 - 0.13 12.5 1.0 0.4 10.9 0.4 2.1 1 1 1 2 2 2 0 N-terminal ig-like domain of cellulase Maf1 PF09174.5 KNZ72147.1 - 2.1e-38 131.9 1.2 7.4e-32 110.6 0.0 2.5 2 0 0 2 2 2 2 Maf1 regulator TPR_2 PF07719.12 KNZ72148.1 - 3.7e-29 98.2 8.7 5.5e-06 25.9 0.1 8.8 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ72148.1 - 2.1e-27 93.5 1.3 2.1e-08 33.3 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ72148.1 - 2.5e-27 94.3 4.0 2.2e-11 43.2 0.1 6.3 6 1 0 6 6 6 4 TPR repeat Apc3 PF12895.2 KNZ72148.1 - 4.7e-24 84.3 6.2 7.2e-14 51.6 0.0 5.3 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KNZ72148.1 - 2.2e-19 69.1 15.1 1.3e-12 47.5 0.6 7.6 6 3 1 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ72148.1 - 3.3e-19 67.1 0.0 2.1e-06 27.1 0.1 7.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ72148.1 - 4.1e-15 55.9 9.0 6.5e-06 26.6 0.0 7.6 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ72148.1 - 1.6e-14 53.9 1.6 0.0009 19.5 0.2 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ72148.1 - 8.5e-14 50.5 2.2 0.0053 16.8 0.0 7.5 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ72148.1 - 6.3e-12 45.0 4.3 0.49 11.1 0.0 8.2 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ72148.1 - 1.1e-09 37.3 7.6 0.019 14.7 0.1 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ72148.1 - 1.3e-09 37.6 7.2 0.0015 18.3 0.1 6.9 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ72148.1 - 1.9e-09 37.3 11.7 0.0022 18.3 0.1 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat SNAP PF14938.1 KNZ72148.1 - 0.002 17.3 0.0 0.039 13.1 0.1 2.6 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_9 PF13371.1 KNZ72148.1 - 0.0059 16.4 2.9 8.5 6.3 0.0 5.2 4 1 0 5 5 5 0 Tetratricopeptide repeat Herpes_UL74 PF07982.7 KNZ72148.1 - 0.006 15.3 0.0 0.0098 14.6 0.0 1.2 1 0 0 1 1 1 1 Herpes UL74 glycoproteins TPR_3 PF07720.7 KNZ72148.1 - 0.0079 15.9 8.9 2.6 7.9 0.0 5.9 8 0 0 8 8 6 1 Tetratricopeptide repeat Cohesin_load PF10345.4 KNZ72148.1 - 0.04 12.1 0.2 0.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Cohesin loading factor TPR_4 PF07721.9 KNZ72148.1 - 0.34 11.4 3.4 49 4.7 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Spectrin PF00435.16 KNZ72149.1 - 0.12 12.6 0.2 0.24 11.7 0.2 1.4 1 0 0 1 1 1 0 Spectrin repeat Pkinase PF00069.20 KNZ72150.1 - 4.2e-61 206.3 0.0 5.8e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72150.1 - 1.3e-32 112.9 0.0 1.9e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ72150.1 - 2.5e-08 33.2 0.0 4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Macro PF01661.16 KNZ72151.1 - 2.9e-29 101.3 0.0 4.6e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Macro domain Sugar_tr PF00083.19 KNZ72152.1 - 4.3e-97 325.5 20.7 1.2e-95 320.7 14.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ72152.1 - 3.6e-26 91.7 48.1 2.3e-21 75.9 16.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 KNZ72152.1 - 0.00055 18.7 0.0 0.0013 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF791) Ank_2 PF12796.2 KNZ72153.1 - 3.1e-08 33.8 0.0 2.8e-06 27.5 0.0 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KNZ72153.1 - 0.00076 19.4 0.3 0.87 10.0 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KNZ72153.1 - 0.0077 16.7 0.0 6.9 7.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KNZ72153.1 - 0.013 15.3 0.1 1 9.3 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat RDM PF11002.3 KNZ72154.1 - 0.021 14.4 0.1 0.047 13.3 0.1 1.6 1 0 0 1 1 1 0 RFPL defining motif (RDM) RRM_1 PF00076.17 KNZ72155.1 - 2.3e-15 55.9 0.0 5e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ72155.1 - 5.2e-12 45.5 0.0 1.1e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ72155.1 - 8.2e-09 35.1 0.0 1.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 KNZ72156.1 - 1.8e-49 168.5 20.6 1.3e-48 165.7 14.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ72156.1 - 1.2e-19 70.2 26.0 1.2e-19 70.2 18.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Complex1_LYR PF05347.10 KNZ72157.1 - 7.3e-12 44.8 0.8 7.3e-12 44.8 0.5 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KNZ72157.1 - 3.6e-11 43.0 1.6 3.9e-11 42.9 0.4 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KNZ72157.1 - 0.0022 18.4 0.6 0.0031 17.9 0.4 1.3 1 1 0 1 1 1 1 Complex1_LYR-like eIF-1a PF01176.14 KNZ72158.1 - 9e-29 98.6 0.2 1.3e-28 98.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 NPR3 PF03666.8 KNZ72160.1 - 2.2e-56 191.3 0.2 6.8e-56 189.6 0.1 1.8 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 AvrL567-A PF11529.3 KNZ72160.1 - 0.075 13.0 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Melampsora lini avirulence protein AvrL567-A RRM_1 PF00076.17 KNZ72161.1 - 7.2e-05 22.3 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KNZ72161.1 - 8.8e-05 22.1 0.4 0.0002 21.0 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 KNZ72161.1 - 9.6e-05 22.1 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ72161.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 KNZ72162.1 - 2.5e-06 27.0 0.9 2.5e-06 27.0 0.6 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KNZ72162.1 - 0.0035 17.2 0.3 0.0035 17.2 0.2 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type LRR_4 PF12799.2 KNZ72164.1 - 6.6e-30 102.2 27.5 2.6e-09 36.4 2.3 8.9 7 1 2 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNZ72164.1 - 1.2e-24 85.8 35.2 6.9e-13 48.1 3.6 8.0 7 2 2 9 9 9 7 Leucine rich repeat LRR_1 PF00560.28 KNZ72164.1 - 1.3e-21 73.2 24.7 0.019 14.8 0.1 11.4 11 1 0 11 11 11 7 Leucine Rich Repeat LRR_6 PF13516.1 KNZ72164.1 - 3.2e-20 69.8 13.7 0.16 12.1 0.0 11.1 11 0 0 11 11 11 5 Leucine Rich repeat LRR_7 PF13504.1 KNZ72164.1 - 1.5e-18 63.6 27.9 0.051 13.7 0.2 11.1 12 0 0 12 12 12 5 Leucine rich repeat LRR_9 PF14580.1 KNZ72164.1 - 0.18 11.3 3.4 4.3 6.8 0.5 3.3 4 0 0 4 4 4 0 Leucine-rich repeat zf-C2H2_4 PF13894.1 KNZ72165.1 - 0.00048 20.2 7.5 0.0065 16.7 0.2 3.4 3 1 1 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KNZ72165.1 - 0.014 15.6 5.9 1 9.8 0.1 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type FYVE PF01363.16 KNZ72165.1 - 0.075 12.9 3.2 0.15 12.0 2.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger SOG2 PF10428.4 KNZ72165.1 - 0.17 10.4 5.6 0.24 10.0 3.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein zf-Di19 PF05605.7 KNZ72165.1 - 0.2 11.8 2.1 2.6 8.2 0.2 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2684 PF10885.3 KNZ72168.1 - 0.09 12.6 1.4 0.61 9.9 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2684) Sigma_reg_N PF13800.1 KNZ72168.1 - 9.3 6.3 7.3 23 5.1 0.4 2.9 2 1 2 4 4 4 0 Sigma factor regulator N-terminal zf-C2H2 PF00096.21 KNZ72169.1 - 7.8e-13 47.9 14.3 9.8e-05 22.4 0.1 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KNZ72169.1 - 1.7e-09 37.4 15.8 0.00015 21.8 0.2 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KNZ72169.1 - 2.9e-09 36.6 15.0 0.0027 17.9 0.1 3.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KNZ72169.1 - 3.6 7.8 9.3 5.5 7.2 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding OrfB_Zn_ribbon PF07282.6 KNZ72169.1 - 4.2 7.0 5.7 8.6 6.1 0.0 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 KNZ72169.1 - 5.6 7.0 8.5 2.7 8.0 0.4 3.2 2 1 2 4 4 4 0 Zinc ribbon domain Thymidylat_synt PF00303.14 KNZ72170.1 - 2.6e-109 364.3 0.0 3e-109 364.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase DUF1295 PF06966.7 KNZ72171.1 - 2.4e-32 112.1 15.8 9.8e-32 110.1 7.3 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1295) ICMT PF04140.9 KNZ72171.1 - 0.013 15.6 0.1 0.046 13.9 0.1 1.9 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Telomere_Sde2 PF13019.1 KNZ72173.1 - 3.7e-30 104.7 1.6 3.7e-30 104.7 1.1 2.2 2 1 0 2 2 2 1 Telomere stability and silencing HMGL-like PF00682.14 KNZ72174.1 - 1.4e-67 227.8 0.8 2e-67 227.3 0.3 1.4 2 0 0 2 2 2 1 HMGL-like Response_reg PF00072.19 KNZ72175.1 - 3.4e-19 68.8 0.0 1.5e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 KNZ72175.1 - 1.6e-14 53.5 0.0 3.4e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KNZ72175.1 - 7.1e-14 51.5 0.1 2.4e-13 49.8 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain UDG PF03167.14 KNZ72176.1 - 6.5e-12 45.1 0.0 1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily bZIP_1 PF00170.16 KNZ72177.1 - 0.00022 21.0 2.2 0.00038 20.3 1.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KNZ72177.1 - 0.0019 17.9 1.0 0.0035 17.1 0.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Helicase_C_3 PF13625.1 KNZ72178.1 - 1.5e-28 99.1 0.1 8.9e-28 96.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ72178.1 - 2.2e-14 53.7 0.1 5.2e-14 52.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KNZ72178.1 - 1.9e-12 46.6 0.1 3.1e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNZ72178.1 - 1.6e-09 37.4 0.0 4.6e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KNZ72178.1 - 2.1e-06 27.3 0.0 4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.1 KNZ72178.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein zf-CCHC PF00098.18 KNZ72179.1 - 1.2e-11 43.9 7.7 1.6e-05 24.6 0.1 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 KNZ72179.1 - 1e-06 28.3 3.7 0.0019 17.9 1.0 2.4 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 KNZ72179.1 - 4.2e-05 23.0 0.0 8.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KNZ72179.1 - 0.00028 20.4 0.0 0.00068 19.2 0.0 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 KNZ72179.1 - 0.00084 18.9 5.4 0.37 10.4 0.2 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 KNZ72179.1 - 0.0012 18.4 6.1 0.27 10.9 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 KNZ72179.1 - 0.063 13.3 5.5 0.13 12.3 3.8 1.4 1 0 0 1 1 1 0 DnaJ central domain CCDC-167 PF15188.1 KNZ72179.1 - 1.3 9.0 6.3 0.37 10.7 0.2 2.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Nol1_Nop2_Fmu PF01189.12 KNZ72180.1 - 3.9e-23 82.2 0.0 7e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 NOL1/NOP2/sun family Fibrillarin PF01269.12 KNZ72180.1 - 0.068 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin CTDII PF01556.13 KNZ72181.1 - 3.9e-21 74.7 0.5 6.3e-18 64.4 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KNZ72181.1 - 4.4e-10 39.4 18.1 7.7e-10 38.6 12.5 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.26 KNZ72181.1 - 8.7e-09 34.9 0.3 1.5e-08 34.1 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Cytochrome_C7 PF14522.1 KNZ72181.1 - 0.045 13.3 8.1 0.24 11.0 0.8 2.4 2 0 0 2 2 2 0 Cytochrome c7 HypA PF01155.14 KNZ72181.1 - 0.084 12.5 11.4 0.46 10.1 3.2 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_CIII PF02085.11 KNZ72181.1 - 0.34 11.0 5.2 0.41 10.7 1.0 2.1 2 0 0 2 2 2 0 Class III cytochrome C family Cytochrom_c3_2 PF14537.1 KNZ72181.1 - 0.53 10.6 12.8 0.59 10.5 3.7 2.2 1 1 1 2 2 2 0 Cytochrome c3 Nucleoplasmin PF03066.10 KNZ72181.1 - 1.2 8.5 4.5 1.9 7.9 3.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin Zn-ribbon_8 PF09723.5 KNZ72181.1 - 5.4 7.0 10.5 0.66 9.9 0.3 3.1 2 1 2 4 4 4 0 Zinc ribbon domain ThuA PF06283.6 KNZ72182.1 - 2.1e-57 194.3 0.0 2.7e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Trehalose utilisation RNase_PH PF01138.16 KNZ72182.1 - 0.026 14.8 0.2 0.054 13.7 0.1 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 ECH PF00378.15 KNZ72184.1 - 5.4e-19 68.2 0.0 1.3e-18 67.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Carboxyl_trans PF01039.17 KNZ72184.1 - 0.069 11.4 0.0 0.1 10.9 0.0 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain Asp PF00026.18 KNZ72185.1 - 7.5e-64 215.9 5.2 9.4e-64 215.6 3.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNZ72185.1 - 1.1e-06 28.7 0.3 2.7e-06 27.4 0.2 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal OB_NTP_bind PF07717.11 KNZ72186.1 - 0.04 13.7 0.0 0.083 12.7 0.0 1.5 1 1 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold DHDPS PF00701.17 KNZ72186.1 - 0.087 11.4 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Cys_Met_Meta_PP PF01053.15 KNZ72187.1 - 4.5e-128 426.8 0.0 5.7e-128 426.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 KNZ72187.1 - 9.5e-18 64.0 0.2 9.3e-17 60.8 0.0 2.9 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KNZ72187.1 - 7.2e-05 22.9 0.1 0.00025 21.1 0.0 2.0 1 1 1 2 2 2 1 GHMP kinases C terminal Aminotran_1_2 PF00155.16 KNZ72187.1 - 0.00011 21.2 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KNZ72187.1 - 0.00015 20.9 0.0 0.00025 20.1 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GalKase_gal_bdg PF10509.4 KNZ72187.1 - 0.0003 20.0 0.0 0.00061 19.0 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Met_gamma_lyase PF06838.6 KNZ72187.1 - 0.00031 19.1 0.0 0.0071 14.6 0.0 2.1 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 KNZ72187.1 - 0.0012 18.0 0.1 0.0035 16.5 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.8 KNZ72187.1 - 0.2 10.3 0.0 0.64 8.6 0.0 1.7 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase Terpene_synth_C PF03936.11 KNZ72188.1 - 5.4e-14 52.0 0.3 7e-14 51.7 0.2 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain RNA_pol_Rpb5_C PF01191.14 KNZ72189.1 - 2.1e-33 113.7 0.2 3.8e-33 112.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KNZ72189.1 - 2.4e-26 91.9 0.0 4.1e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KNZ72189.1 - 0.0012 18.6 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease WD40 PF00400.27 KNZ72190.1 - 9.3e-25 85.5 2.4 1.5e-08 34.2 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KNZ72190.1 - 0.0059 15.4 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region TRAP_alpha PF03896.11 KNZ72192.1 - 6.4e-07 28.6 0.0 7.8e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit tRNA_synt_1c_R1 PF04558.10 KNZ72193.1 - 0.061 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 GET2 PF08690.5 KNZ72193.1 - 0.086 12.0 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 AA_permease PF00324.16 KNZ72196.1 - 1.3e-112 376.6 47.6 1.5e-112 376.3 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KNZ72196.1 - 5e-35 120.8 52.7 6.1e-35 120.5 36.5 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 KNZ72196.1 - 0.0048 17.0 0.3 0.0048 17.0 0.2 3.5 4 1 1 5 5 5 1 PrgI family protein PSI PF01437.20 KNZ72197.1 - 0.053 13.6 2.0 0.053 13.6 1.4 1.8 2 0 0 2 2 2 0 Plexin repeat SART-1 PF03343.8 KNZ72197.1 - 0.057 11.7 0.2 0.076 11.3 0.2 1.1 1 0 0 1 1 1 0 SART-1 family XH PF03469.9 KNZ72198.1 - 0.08 12.6 0.5 0.82 9.3 0.0 2.2 2 0 0 2 2 2 0 XH domain Glyoxalase_4 PF13669.1 KNZ72199.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RNA_lig_T4_1 PF09511.5 KNZ72201.1 - 5e-77 258.3 0.0 1e-76 257.3 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 KNZ72201.1 - 3.2e-23 82.4 0.1 1.1e-22 80.6 0.0 2.0 2 0 0 2 2 2 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 KNZ72201.1 - 1.1e-14 54.2 0.1 5.5e-14 52.0 0.0 2.0 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain KTI12 PF08433.5 KNZ72201.1 - 0.00057 19.1 0.0 0.03 13.5 0.0 2.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KNZ72201.1 - 0.0057 16.5 0.2 0.019 14.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain DUF1280 PF06918.9 KNZ72201.1 - 0.066 12.4 0.1 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) CENP-F_leu_zip PF10473.4 KNZ72202.1 - 0.0016 18.3 7.3 0.0023 17.7 5.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 KNZ72202.1 - 0.0097 14.4 8.6 0.013 13.9 6.0 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light IncA PF04156.9 KNZ72202.1 - 0.02 14.4 10.1 0.034 13.7 7.0 1.3 1 0 0 1 1 1 0 IncA protein Peptidase_C12 PF01088.16 KNZ72203.1 - 2e-54 184.0 0.0 3e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Med31 PF05669.7 KNZ72204.1 - 1.8e-33 114.3 4.4 2.1e-33 114.1 3.0 1.0 1 0 0 1 1 1 1 SOH1 TPT PF03151.11 KNZ72205.1 - 2e-28 98.9 8.5 2e-28 98.9 5.9 2.6 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 KNZ72205.1 - 5.9e-07 29.5 32.7 0.00087 19.3 9.5 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KNZ72205.1 - 8.4e-07 28.1 19.3 1.6e-06 27.2 13.0 1.8 1 1 0 1 1 1 1 UAA transporter family Fungal_trans PF04082.13 KNZ72206.1 - 5.4e-06 25.4 0.1 9.1e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ72206.1 - 7.1e-06 25.8 12.3 1.2e-05 25.1 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 KNZ72206.1 - 0.038 13.3 9.0 0.05 13.0 6.2 1.1 1 0 0 1 1 1 0 Vta1 like DUF218 PF02698.12 KNZ72207.1 - 6.9e-08 32.1 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain NicO PF03824.11 KNZ72207.1 - 0.013 14.8 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Fungal_trans PF04082.13 KNZ72208.1 - 1.7e-23 82.8 0.8 2.6e-23 82.2 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KNZ72208.1 - 2.6e-07 30.5 10.3 2.2e-06 27.6 2.3 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KNZ72208.1 - 4e-06 26.8 17.1 0.0039 17.4 3.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ72208.1 - 0.00015 21.8 20.0 0.00017 21.6 3.4 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KNZ72208.1 - 0.0018 18.0 1.4 0.0018 18.0 1.0 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KNZ72208.1 - 0.079 13.1 6.8 0.41 10.8 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Lar_restr_allev PF14354.1 KNZ72208.1 - 0.27 11.5 1.7 0.66 10.3 1.2 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-met PF12874.2 KNZ72208.1 - 1.3 9.3 5.6 20 5.5 0.5 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Hydrolase_like PF13242.1 KNZ72209.1 - 7.3e-23 80.0 0.0 1.9e-22 78.7 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 KNZ72209.1 - 7e-13 48.3 0.0 1.3e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KNZ72209.1 - 0.00018 21.7 0.0 0.00036 20.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase O-FucT PF10250.4 KNZ72210.1 - 2e-05 23.8 0.0 0.00031 19.9 0.0 2.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase SAM_2 PF07647.12 KNZ72211.1 - 8e-06 25.6 0.0 2.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KNZ72211.1 - 5.5e-05 23.2 0.0 0.00018 21.5 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RhoGAP PF00620.22 KNZ72212.1 - 7.4e-30 103.5 0.0 1.2e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.12 KNZ72212.1 - 3.7e-28 97.7 0.0 8.4e-28 96.6 0.0 1.6 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.21 KNZ72212.1 - 5.4e-09 35.7 3.3 3e-05 23.7 2.5 2.7 2 0 0 2 2 2 2 WW domain p450 PF00067.17 KNZ72214.1 - 4.8e-66 223.1 0.0 2e-65 221.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 FB_lectin PF07367.6 KNZ72215.1 - 0.00058 19.4 0.0 0.00064 19.3 0.0 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin FB_lectin PF07367.6 KNZ72216.1 - 4.7e-28 97.5 0.0 5.2e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin Toxin_3 PF00537.13 KNZ72216.1 - 0.09 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Scorpion toxin-like domain TPT PF03151.11 KNZ72217.1 - 2.4e-23 82.4 17.1 5.5e-20 71.5 3.3 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 KNZ72217.1 - 6e-10 38.5 10.1 5.5e-05 22.2 0.5 2.3 2 1 0 2 2 2 2 UAA transporter family EamA PF00892.15 KNZ72217.1 - 9.3e-08 32.1 25.5 1.9e-05 24.6 5.5 3.2 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KNZ72217.1 - 0.018 14.1 4.2 0.83 8.7 0.3 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter EmrE PF13536.1 KNZ72217.1 - 0.13 12.5 17.0 0.098 12.8 3.9 3.1 2 1 1 3 3 3 0 Multidrug resistance efflux transporter HNH_2 PF13391.1 KNZ72218.1 - 1.4e-06 28.0 0.0 3.4e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease zf-RVT PF13966.1 KNZ72219.1 - 0.0084 16.3 3.8 0.018 15.3 2.6 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase UPF0556 PF10572.4 KNZ72220.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 UCH PF00443.24 KNZ72222.1 - 7.1e-33 113.8 0.0 1.3e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 KNZ72222.1 - 8.9e-22 76.2 2.9 5.7e-11 41.9 0.3 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 KNZ72222.1 - 4.1e-14 52.7 0.0 2.9e-13 49.9 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KNZ72222.1 - 3.8e-13 49.3 6.7 1e-07 31.9 0.0 3.3 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein DUF1814 PF08843.6 KNZ72223.1 - 8.5e-05 22.4 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) DUF2204 PF09970.4 KNZ72223.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) POPLD PF08170.7 KNZ72223.1 - 0.062 13.1 0.1 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 POPLD (NUC188) domain DUF4473 PF14747.1 KNZ72223.1 - 0.078 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) NTP_transf_5 PF14907.1 KNZ72223.1 - 0.086 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase Transgly PF00912.17 KNZ72223.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase GST_N_3 PF13417.1 KNZ72224.1 - 1.3e-13 50.9 0.1 2.6e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KNZ72224.1 - 1.3e-10 41.1 0.0 2.4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KNZ72224.1 - 6e-06 26.0 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KNZ72224.1 - 1.8e-05 24.6 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N PF02798.15 KNZ72224.1 - 9.8e-05 22.4 0.0 0.00022 21.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KNZ72224.1 - 0.0089 15.9 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KNZ72224.1 - 0.023 15.1 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PQ-loop PF04193.9 KNZ72225.1 - 2.1e-26 91.1 13.1 7.4e-18 63.8 0.5 2.7 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.13 KNZ72225.1 - 0.052 14.0 4.7 0.071 13.5 1.3 2.4 2 1 1 3 3 3 0 ER lumen protein retaining receptor Pox_I5 PF04713.7 KNZ72225.1 - 1.1 9.0 4.4 0.18 11.5 0.5 1.6 2 0 0 2 2 2 0 Poxvirus protein I5 MtN3_slv PF03083.11 KNZ72225.1 - 2.3 8.1 7.4 18 5.2 0.3 3.1 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange DUF1814 PF08843.6 KNZ72226.1 - 0.0002 21.2 0.1 0.00028 20.7 0.1 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) NTP_transf_2 PF01909.18 KNZ72226.1 - 0.018 15.3 0.0 0.028 14.7 0.0 1.7 1 1 0 1 1 1 0 Nucleotidyltransferase domain NTP_transf_5 PF14907.1 KNZ72226.1 - 0.069 12.4 0.1 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised nucleotidyltransferase Mito_carr PF00153.22 KNZ72227.1 - 1.5e-65 216.9 4.3 6.5e-22 77.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2345 PF10106.4 KNZ72227.1 - 0.0033 17.0 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2345) AAA_28 PF13521.1 KNZ72228.1 - 6e-21 75.0 0.0 6.8e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain TOMM6 PF15184.1 KNZ72228.1 - 0.14 11.5 0.2 0.45 9.8 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM6 homolog Sec63 PF02889.11 KNZ72229.1 - 1.4e-191 635.4 0.0 9.4e-100 333.8 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KNZ72229.1 - 3.1e-44 150.4 0.6 1.7e-20 73.1 0.3 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 KNZ72229.1 - 1.8e-11 44.2 0.1 0.00019 21.3 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KNZ72229.1 - 6.2e-11 41.9 0.0 6.5e-09 35.5 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KNZ72229.1 - 0.0011 19.1 0.0 0.56 10.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 KNZ72229.1 - 0.0019 17.4 0.1 0.011 14.9 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 KNZ72229.1 - 0.04 12.8 0.0 0.11 11.3 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Pkinase PF00069.20 KNZ72230.1 - 1.5e-22 79.9 0.0 1e-18 67.4 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72230.1 - 4.9e-06 25.8 0.7 0.073 12.1 0.0 2.9 3 1 1 4 4 4 2 Protein tyrosine kinase RNase_H PF00075.19 KNZ72233.1 - 3.2e-14 53.3 0.0 6.4e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 KNZ72233.1 - 0.00044 19.8 0.9 0.0017 17.9 0.1 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Zn_Tnp_IS1595 PF12760.2 KNZ72233.1 - 0.0037 17.0 0.5 0.016 15.0 0.4 2.1 1 0 0 1 1 1 1 Transposase zinc-ribbon domain RVP_2 PF08284.6 KNZ72237.1 - 0.007 16.3 0.1 0.012 15.5 0.0 1.3 1 1 0 1 1 1 1 Retroviral aspartyl protease UBN2_2 PF14227.1 KNZ72238.1 - 0.011 15.2 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF2288 PF10052.4 KNZ72238.1 - 0.13 11.9 0.1 14 5.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2288) zf-CCHC PF00098.18 KNZ72239.1 - 0.016 15.0 0.7 0.04 13.8 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 KNZ72239.1 - 0.061 12.8 0.3 0.14 11.6 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle polyprenyl_synt PF00348.12 KNZ72240.1 - 2.4e-37 128.2 0.0 3.3e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Collagen PF01391.13 KNZ72242.1 - 0.012 15.1 6.9 0.012 15.1 4.8 1.5 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Dynamin_N PF00350.18 KNZ72243.1 - 1.9e-28 99.3 0.0 3.4e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KNZ72243.1 - 3.4e-19 68.7 0.0 6.8e-19 67.7 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region GED PF02212.13 KNZ72243.1 - 9.4e-10 38.2 0.0 2.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KNZ72243.1 - 0.00047 20.0 0.0 0.0028 17.6 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Hemerythrin PF01814.18 KNZ72243.1 - 0.0096 16.0 0.0 0.032 14.3 0.0 1.9 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Miro PF08477.8 KNZ72243.1 - 0.014 15.9 0.0 0.028 14.9 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 KNZ72243.1 - 0.056 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KNZ72243.1 - 0.089 13.0 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.22 KNZ72243.1 - 0.11 11.9 0.0 13 5.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_M PF01031.15 KNZ72244.1 - 9.2e-29 100.1 0.0 6.2e-19 67.8 0.0 2.4 2 1 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 KNZ72244.1 - 1.6e-26 93.1 0.0 2.9e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KNZ72244.1 - 8e-09 35.2 0.0 3.1e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KNZ72244.1 - 0.00075 19.4 0.0 0.0032 17.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KNZ72244.1 - 0.021 14.8 0.0 0.057 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KNZ72244.1 - 0.024 15.1 0.0 0.057 13.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Hemerythrin PF01814.18 KNZ72244.1 - 0.025 14.7 0.1 0.099 12.8 0.0 2.1 2 0 0 2 2 1 0 Hemerythrin HHE cation binding domain AAA_29 PF13555.1 KNZ72244.1 - 0.045 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KNZ72244.1 - 0.077 12.4 0.0 15 4.9 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KNZ72244.1 - 0.086 13.1 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 KNZ72244.1 - 0.098 12.3 0.1 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Peptidase_M75 PF09375.5 KNZ72244.1 - 0.12 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Imelysin Metallophos PF00149.23 KNZ72246.1 - 6.1e-08 32.2 0.2 1.2e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KNZ72246.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF596 PF04591.7 KNZ72247.1 - 0.9 9.4 3.5 1.8 8.5 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function, DUF596 Peptidase_C14 PF00656.17 KNZ72248.1 - 4e-27 95.5 0.0 4.8e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Ceramidase_alk PF04734.8 KNZ72253.1 - 1.7e-248 825.9 0.0 1.9e-248 825.8 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Cellulase PF00150.13 KNZ72255.1 - 1.1e-07 31.3 0.0 1.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-CCHC PF00098.18 KNZ72258.1 - 0.016 15.1 0.4 0.03 14.2 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle MSA-2c PF12238.3 KNZ72258.1 - 0.37 10.4 3.6 0.79 9.3 2.5 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c Asp_protease_2 PF13650.1 KNZ72259.1 - 3.9e-05 24.0 0.0 7.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ72259.1 - 0.00033 20.2 0.1 0.00051 19.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease NSP10 PF09401.5 KNZ72259.1 - 0.11 12.2 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 RNA synthesis protein NSP10 UPF0147 PF03685.8 KNZ72260.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Pinin_SDK_memA PF04696.8 KNZ72261.1 - 9.6e-09 34.9 10.7 1.9e-08 33.9 7.5 1.4 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region ATP-synt_E PF05680.7 KNZ72261.1 - 0.99 9.4 5.4 4 7.4 3.7 2.0 1 1 0 1 1 1 0 ATP synthase E chain TPR_16 PF13432.1 KNZ72262.1 - 1.5e-12 47.8 6.6 6.2e-06 26.7 0.8 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ72262.1 - 4.9e-07 29.3 3.7 0.02 14.5 0.0 3.1 3 0 0 3 3 3 2 TPR repeat Apc3 PF12895.2 KNZ72262.1 - 4.3e-06 26.7 5.4 0.0011 19.0 1.5 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KNZ72262.1 - 8.5e-06 25.9 8.3 0.042 14.4 0.0 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ72262.1 - 1.4e-05 25.2 9.3 0.00087 19.5 1.0 3.1 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ72262.1 - 4.9e-05 22.9 5.4 0.45 10.5 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 KNZ72262.1 - 0.00028 20.0 3.7 0.0075 15.3 0.8 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ72262.1 - 0.00055 20.2 3.8 1.6 9.3 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat SRP72 PF08492.7 KNZ72262.1 - 0.0022 18.3 2.9 0.0055 17.0 2.0 1.7 1 0 0 1 1 1 1 SRP72 RNA-binding domain TPR_9 PF13371.1 KNZ72262.1 - 0.011 15.6 10.9 0.038 13.8 0.2 3.6 2 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ72262.1 - 0.032 14.0 0.5 1.6 8.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ72262.1 - 0.079 12.9 7.7 0.086 12.7 1.9 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ72262.1 - 0.31 10.7 4.0 13 5.6 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ72262.1 - 4.9 7.2 11.4 5.9 6.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat His_Phos_2 PF00328.17 KNZ72263.1 - 0.0023 17.3 0.0 0.012 15.0 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF2242 PF10001.4 KNZ72264.1 - 0.0058 16.4 0.1 0.015 15.1 0.1 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2242) DUF4227 PF14004.1 KNZ72264.1 - 0.078 12.8 0.0 0.078 12.8 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4227) DUF1129 PF06570.6 KNZ72264.1 - 0.08 12.2 0.3 12 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Drf_FH1 PF06346.7 KNZ72265.1 - 4 6.9 24.8 37 3.7 17.2 2.4 1 1 0 1 1 1 0 Formin Homology Region 1 FAD_binding_7 PF03441.9 KNZ72266.1 - 8.5e-43 146.5 0.5 1.4e-42 145.8 0.3 1.2 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase RICTOR_N PF14664.1 KNZ72270.1 - 0.0027 16.3 0.2 0.83 8.1 0.0 2.4 2 1 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term TIR PF01582.15 KNZ72270.1 - 0.52 9.7 6.0 4.5 6.7 0.4 2.5 2 1 0 2 2 2 0 TIR domain Occludin_ELL PF07303.8 KNZ72270.1 - 5 7.9 11.7 4.4 8.0 1.5 2.6 1 1 2 3 3 3 0 Occludin homology domain Polysacc_lyase PF14099.1 KNZ72271.1 - 1.8e-07 31.0 0.1 1.9e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide lyase BetaGal_dom4_5 PF13364.1 KNZ72271.1 - 0.004 17.4 0.0 0.0063 16.7 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Glyco_hydro_7 PF00840.15 KNZ72273.1 - 2.4e-195 648.9 19.5 2.6e-194 645.5 13.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 DUF4098 PF13345.1 KNZ72274.1 - 0.24 11.3 4.4 0.13 12.1 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4098) zf-CCHC PF00098.18 KNZ72275.1 - 0.023 14.6 0.5 0.044 13.7 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF2967 PF11179.3 KNZ72277.1 - 0.029 13.8 0.4 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) SPT2 PF08243.6 KNZ72277.1 - 7 6.9 10.7 16 5.8 7.4 1.6 1 0 0 1 1 1 0 SPT2 chromatin protein MCM PF00493.18 KNZ72279.1 - 7.7e-34 116.9 0.0 8.9e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 MCM2/3/5 family AAA_5 PF07728.9 KNZ72279.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pyridoxal_deC PF00282.14 KNZ72280.1 - 2.3e-115 385.0 0.0 2.7e-115 384.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain OKR_DC_1 PF01276.15 KNZ72280.1 - 0.054 12.0 0.0 0.085 11.3 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.14 KNZ72280.1 - 0.063 12.0 0.0 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_1_2 PF00155.16 KNZ72280.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Tyrosinase PF00264.15 KNZ72281.1 - 2.3e-12 47.5 0.4 3.2e-12 47.0 0.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase V-SNARE PF05008.10 KNZ72283.1 - 1.2e-18 66.9 5.3 4e-18 65.3 0.9 2.3 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 KNZ72283.1 - 2.6e-12 46.6 4.0 5.6e-12 45.5 2.7 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KNZ72283.1 - 4e-05 23.2 0.4 0.00018 21.1 0.0 2.0 2 0 0 2 2 2 1 Sec20 DUF912 PF06024.7 KNZ72283.1 - 0.018 15.0 0.2 0.076 13.0 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Prominin PF05478.6 KNZ72283.1 - 0.022 12.3 0.8 0.2 9.1 0.0 2.0 1 1 1 2 2 2 0 Prominin TrwC PF08751.6 KNZ72283.1 - 0.044 13.2 0.2 0.065 12.6 0.1 1.3 1 0 0 1 1 1 0 TrwC relaxase DASH_Duo1 PF08651.5 KNZ72283.1 - 0.16 11.5 0.5 0.6 9.7 0.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF2721 PF11026.3 KNZ72283.1 - 0.36 10.4 3.2 0.23 11.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF4381 PF14316.1 KNZ72284.1 - 0.0071 16.4 0.6 0.26 11.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) Far-17a_AIG1 PF04750.9 KNZ72284.1 - 0.012 14.7 1.8 0.014 14.5 1.2 1.1 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein Yip1 PF04893.12 KNZ72284.1 - 0.044 13.2 0.6 0.052 13.0 0.4 1.1 1 0 0 1 1 1 0 Yip1 domain Herpes_glycop PF01528.11 KNZ72284.1 - 0.072 11.7 0.1 0.08 11.6 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Mpv17_PMP22 PF04117.7 KNZ72285.1 - 3.6e-24 84.1 1.1 5.6e-24 83.5 0.8 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.11 KNZ72287.1 - 1.8e-35 122.3 46.3 1.6e-31 109.3 33.1 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KNZ72287.1 - 1.3e-10 40.1 25.4 6e-10 37.9 17.6 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 KNZ72290.1 - 1e-68 232.0 0.0 3.1e-68 230.4 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 CBM_1 PF00734.13 KNZ72293.1 - 1.9e-11 43.3 12.7 1.9e-11 43.3 8.8 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Esterase_phd PF10503.4 KNZ72293.1 - 5.6e-08 32.3 0.2 6.9e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase RNase_H PF00075.19 KNZ72294.1 - 0.0001 22.6 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 RNase H Laminin_G_3 PF13385.1 KNZ72294.1 - 0.085 13.0 0.2 0.11 12.6 0.2 1.3 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily SpoU_methylase PF00588.14 KNZ72294.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 SpoU rRNA Methylase family RVT_1 PF00078.22 KNZ72295.1 - 0.00015 21.1 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KNZ72296.1 - 0.0052 16.1 0.0 0.0052 16.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 KNZ72297.1 - 3.8e-10 39.4 0.6 5.2e-10 38.9 0.4 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KNZ72297.1 - 0.00015 21.7 0.2 0.00017 21.6 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DEC-1_N PF04625.8 KNZ72298.1 - 4.8 5.7 15.6 5.5 5.5 10.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF4106 PF13388.1 KNZ72298.1 - 5.1 5.9 6.4 6.1 5.6 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Atrophin-1 PF03154.10 KNZ72298.1 - 7 4.6 14.7 7.8 4.4 10.2 1.0 1 0 0 1 1 1 0 Atrophin-1 family BAR_2 PF10455.4 KNZ72301.1 - 1.4e-17 63.5 1.2 1.6e-17 63.3 0.8 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KNZ72301.1 - 0.00093 18.7 1.4 0.001 18.6 1.0 1.0 1 0 0 1 1 1 1 BAR domain PAP_fibrillin PF04755.7 KNZ72301.1 - 0.029 14.0 0.3 0.048 13.3 0.1 1.4 1 1 0 1 1 1 0 PAP_fibrillin PuR_N PF09182.5 KNZ72301.1 - 0.13 11.8 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal DUF959 PF06121.9 KNZ72302.1 - 0.078 12.6 1.6 0.1 12.2 1.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) Sigma70_ner PF04546.8 KNZ72302.1 - 0.39 10.3 7.0 0.15 11.6 2.5 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Bd3614_N PF14442.1 KNZ72302.1 - 0.7 9.8 4.5 0.2 11.5 1.4 1.5 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Nha1_C PF08619.5 KNZ72302.1 - 0.8 8.9 17.8 1.3 8.1 12.3 1.3 1 1 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF3245 PF11595.3 KNZ72302.1 - 0.98 9.6 6.4 0.12 12.6 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) CENP-B_dimeris PF09026.5 KNZ72302.1 - 1.2 9.4 9.0 0.16 12.1 3.5 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PRP1_N PF06424.7 KNZ72302.1 - 1.9 8.8 7.4 4.3 7.6 0.6 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DNA_pol_phi PF04931.8 KNZ72302.1 - 3.9 5.1 8.5 5.4 4.6 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Myc_N PF01056.13 KNZ72302.1 - 5.1 6.1 13.7 9.6 5.2 9.5 1.6 1 1 0 1 1 1 0 Myc amino-terminal region PBP1_TM PF14812.1 KNZ72302.1 - 8.3 6.7 18.4 0.5 10.7 7.9 2.1 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0560 PF10577.4 KNZ72302.1 - 9.7 4.3 8.8 12 4.0 6.1 1.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0560 Pyr_redox_2 PF07992.9 KNZ72303.1 - 5.5e-39 134.1 1.1 1.2e-38 133.0 0.7 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KNZ72303.1 - 2.7e-33 114.2 0.6 9.3e-33 112.5 0.1 2.1 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KNZ72303.1 - 2.2e-19 69.6 3.1 6.9e-18 64.8 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNZ72303.1 - 1.4e-09 38.2 0.1 0.00014 22.0 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KNZ72303.1 - 8.4e-07 27.8 0.6 0.00052 18.5 0.0 2.4 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.1 KNZ72303.1 - 2e-06 26.9 0.0 5.2e-06 25.6 0.0 1.5 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 KNZ72303.1 - 2e-05 23.8 0.3 5.7e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ72303.1 - 0.00013 20.9 2.3 0.018 13.9 0.5 2.5 1 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KNZ72303.1 - 0.0014 18.6 0.3 0.004 17.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KNZ72303.1 - 0.028 13.3 9.5 0.33 9.8 0.8 2.9 3 1 1 4 4 4 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KNZ72303.1 - 0.029 14.0 0.1 0.029 14.0 0.1 2.4 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KNZ72303.1 - 0.035 13.8 0.9 0.24 11.1 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 KNZ72303.1 - 0.053 13.0 0.1 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 KNZ72303.1 - 1.4 7.6 6.3 0.34 9.7 0.1 2.8 3 1 1 4 4 4 0 Glucose inhibited division protein A PI-PLC-X PF00388.14 KNZ72304.1 - 2.3e-05 23.7 0.0 4.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DBD_Tnp_Mut PF03108.10 KNZ72304.1 - 0.1 12.1 1.2 0.16 11.5 0.2 1.7 2 0 0 2 2 2 0 MuDR family transposase WD40 PF00400.27 KNZ72305.1 - 6.6e-68 222.3 24.7 2.1e-11 43.2 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KNZ72305.1 - 2.1e-11 42.7 10.0 0.008 14.3 0.1 4.7 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 KNZ72305.1 - 0.00096 18.9 0.4 0.021 14.5 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Pox_A_type_inc PF04508.7 KNZ72305.1 - 0.085 12.6 0.3 0.28 11.0 0.2 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat VCBS PF13517.1 KNZ72308.1 - 4.4e-23 81.4 13.9 1.9e-07 31.2 1.1 5.5 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KNZ72308.1 - 6.4e-09 35.2 25.1 0.021 14.4 1.7 7.1 7 1 0 7 7 7 4 FG-GAP repeat TcdB_toxin_midN PF12256.3 KNZ72308.1 - 7.8e-07 28.7 7.6 0.81 9.1 0.0 6.1 5 2 1 6 6 6 4 Insecticide toxin TcdB middle/N-terminal region Cerato-platanin PF07249.7 KNZ72310.1 - 1.5e-46 157.2 0.9 1.7e-46 157.1 0.6 1.0 1 0 0 1 1 1 1 Cerato-platanin Plant_tran PF04827.9 KNZ72310.1 - 0.00087 18.7 0.1 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein Glyco_hydro_45 PF02015.11 KNZ72310.1 - 0.06 13.4 1.4 0.066 13.2 1.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 Cerato-platanin PF07249.7 KNZ72311.1 - 6.6e-45 151.9 0.4 7.6e-45 151.7 0.2 1.0 1 0 0 1 1 1 1 Cerato-platanin ABC2_membrane PF01061.19 KNZ72312.1 - 1.2e-37 129.1 18.8 1.2e-37 129.1 13.0 2.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KNZ72312.1 - 3.4e-24 85.6 0.0 7e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KNZ72312.1 - 6.7e-05 22.9 0.3 0.37 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KNZ72312.1 - 0.00014 21.0 0.3 0.0016 17.6 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 KNZ72312.1 - 0.0012 18.0 31.7 0.0021 17.1 19.7 2.7 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_22 PF13401.1 KNZ72312.1 - 0.0065 16.6 0.2 0.019 15.1 0.1 1.7 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 KNZ72312.1 - 0.011 16.5 0.2 0.023 15.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KNZ72312.1 - 0.026 14.8 0.2 0.05 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KNZ72312.1 - 0.027 14.3 0.2 0.061 13.2 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KNZ72312.1 - 0.03 13.8 0.2 0.047 13.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KNZ72312.1 - 0.034 13.6 0.1 0.088 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 KNZ72312.1 - 0.037 13.9 0.2 0.061 13.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KNZ72312.1 - 0.04 13.3 0.1 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 KNZ72312.1 - 0.048 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KNZ72312.1 - 0.053 13.7 1.1 0.16 12.1 0.2 2.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNZ72312.1 - 0.069 13.1 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 KNZ72312.1 - 0.07 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 KNZ72312.1 - 0.16 10.7 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain HD PF01966.17 KNZ72312.1 - 0.19 11.7 0.1 6.8 6.7 0.0 2.3 2 0 0 2 2 2 0 HD domain AAA_23 PF13476.1 KNZ72312.1 - 0.29 11.4 0.0 0.62 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain COX17 PF05051.8 KNZ72313.1 - 2.1e-19 69.2 3.1 2.1e-19 69.2 2.1 1.5 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) E1-E2_ATPase PF00122.15 KNZ72314.1 - 7.3e-50 169.1 2.8 1.6e-49 167.9 0.7 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KNZ72314.1 - 3.6e-32 112.5 0.0 7.7e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KNZ72314.1 - 1.4e-23 83.3 12.5 3.9e-17 62.3 1.4 3.5 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KNZ72314.1 - 1.9e-18 66.2 0.0 3.8e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KNZ72314.1 - 1.3e-14 53.3 0.0 4.4e-14 51.6 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KNZ72314.1 - 2.3e-14 53.9 0.0 5.8e-14 52.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KNZ72314.1 - 5e-05 23.0 1.1 0.02 14.4 0.5 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_efflux PF01545.16 KNZ72314.1 - 0.0032 16.5 4.3 0.089 11.8 1.7 2.8 3 1 0 3 3 3 1 Cation efflux family DUF1691 PF07950.6 KNZ72315.1 - 4.5e-09 36.1 1.7 0.0011 18.8 0.5 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1691) RST PF12174.3 KNZ72315.1 - 0.08 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain Pkinase PF00069.20 KNZ72316.1 - 5.8e-28 97.7 0.0 2.6e-27 95.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72316.1 - 4.8e-10 38.9 0.0 2.7e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ72316.1 - 2.1e-05 23.6 0.0 0.05 12.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KNZ72316.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sporozoite_P67 PF05642.6 KNZ72316.1 - 0.6 7.9 3.7 0.76 7.5 2.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Gly-zipper_OmpA PF13436.1 KNZ72316.1 - 3.6 7.2 9.8 0.45 10.1 3.1 2.0 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain F-box PF00646.28 KNZ72317.1 - 1.5e-09 37.2 1.5 4.2e-09 35.8 1.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KNZ72317.1 - 3.4e-06 26.6 0.3 8.1e-06 25.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like Terpene_synth_C PF03936.11 KNZ72319.1 - 8.2e-15 54.7 0.0 9.6e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Sec1 PF00995.18 KNZ72319.1 - 0.0018 16.9 0.0 0.92 8.0 0.0 2.1 2 0 0 2 2 2 2 Sec1 family DDOST_48kD PF03345.9 KNZ72320.1 - 6.7e-104 347.7 0.0 7.6e-104 347.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta BCSC_C PF05420.6 KNZ72320.1 - 0.0073 15.4 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Cellulose synthase operon protein C C-terminus (BCSC_C) Endotoxin_M PF00555.14 KNZ72320.1 - 0.028 14.2 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 delta endotoxin ADK PF00406.17 KNZ72321.1 - 7.4e-59 197.9 0.0 9.1e-59 197.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KNZ72321.1 - 7.4e-15 54.3 0.0 1.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 KNZ72321.1 - 0.00023 21.0 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ72321.1 - 0.0012 19.6 0.0 0.002 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KNZ72321.1 - 0.0033 16.5 0.1 0.0049 15.9 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KNZ72321.1 - 0.041 14.2 0.0 0.088 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 KNZ72322.1 - 7.9e-10 38.0 0.5 1.3e-09 37.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ72322.1 - 0.0057 16.5 5.8 0.011 15.5 4.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp_protease_2 PF13650.1 KNZ72323.1 - 0.00014 22.3 0.0 0.00033 21.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ72323.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Lactamase_B PF00753.22 KNZ72324.1 - 1.1e-16 61.0 1.4 2e-16 60.2 1.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KNZ72324.1 - 0.001 18.6 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MIF4G PF02854.14 KNZ72326.1 - 4.9e-26 91.4 3.4 7.7e-24 84.2 0.1 2.5 2 1 0 2 2 2 2 MIF4G domain MA3 PF02847.12 KNZ72326.1 - 2.6e-23 81.8 0.1 5.4e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 MA3 domain CDC45 PF02724.9 KNZ72326.1 - 0.0042 15.2 2.0 0.0042 15.2 1.4 2.4 2 1 0 2 2 2 1 CDC45-like protein GCIP PF13324.1 KNZ72326.1 - 4.2 6.5 8.5 2 7.5 0.1 2.3 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Nop25 PF09805.4 KNZ72326.1 - 5.5 7.0 10.6 9.5 6.2 0.1 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Vfa1 PF08432.5 KNZ72326.1 - 8.8 6.3 10.3 7.1 6.6 1.2 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 HEAT PF02985.17 KNZ72327.1 - 0.018 15.1 0.2 0.051 13.6 0.1 1.8 2 0 0 2 2 2 0 HEAT repeat DUF2435 PF10363.4 KNZ72327.1 - 0.051 13.4 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 KNZ72327.1 - 0.13 12.8 0.4 0.2 12.1 0.3 1.4 1 1 0 1 1 1 0 HEAT-like repeat RVP_2 PF08284.6 KNZ72328.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KNZ72328.1 - 0.045 13.5 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ72328.1 - 0.1 13.0 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease Exo_endo_phos PF03372.18 KNZ72333.1 - 0.038 13.9 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DNA_pol_alpha_N PF12254.3 KNZ72334.1 - 0.053 13.3 1.2 0.098 12.4 0.8 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal PIF1 PF05970.9 KNZ72337.1 - 6.7e-05 22.0 0.0 7.5e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ72337.1 - 0.0098 15.4 0.1 0.012 15.1 0.1 1.1 1 0 0 1 1 1 1 AAA domain YvrJ PF12841.2 KNZ72338.1 - 0.064 12.5 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 YvrJ protein family Pkinase PF00069.20 KNZ72339.1 - 4.8e-10 39.0 0.0 8.1e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72339.1 - 0.0013 17.8 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KNZ72339.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 1 0 1 1 1 0 RIO1 family RNase_H PF00075.19 KNZ72341.1 - 2e-11 44.3 0.0 3.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 KNZ72341.1 - 0.046 14.0 1.5 0.067 13.5 0.5 1.6 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase SAGA-Tad1 PF12767.2 KNZ72343.1 - 0.032 13.9 8.9 0.047 13.3 6.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Ribonucleas_3_3 PF14622.1 KNZ72344.1 - 1e-08 35.1 0.0 2.7e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.20 KNZ72344.1 - 5.6e-07 30.0 0.0 1.5e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 KNZ72344.1 - 0.022 15.1 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease III domain Helicase_C PF00271.26 KNZ72344.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain SNF2_N PF00176.18 KNZ72345.1 - 7.8e-41 139.8 0.0 1.3e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KNZ72345.1 - 2.4e-06 27.1 0.0 1.2e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-PHD-like PF15446.1 KNZ72345.1 - 0.00016 21.0 4.4 0.00016 21.0 3.1 3.4 3 2 0 3 3 3 1 PHD/FYVE-zinc-finger like domain Chromo PF00385.19 KNZ72345.1 - 0.013 15.1 5.8 0.38 10.4 0.1 3.0 3 0 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain C1_1 PF00130.17 KNZ72345.1 - 0.062 13.0 0.3 0.062 13.0 0.2 4.3 5 0 0 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 KNZ72345.1 - 2.4 7.9 18.8 1.5 8.6 0.1 4.5 4 1 0 4 4 4 0 PHD-finger DUF2305 PF10230.4 KNZ72346.1 - 2.2e-16 60.0 0.1 2.4e-16 59.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Sec8_exocyst PF04048.9 KNZ72347.1 - 1.3e-25 89.6 0.2 2.5e-25 88.7 0.2 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KNZ72347.1 - 5e-06 25.6 0.4 1.2e-05 24.4 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Helitron_like_N PF14214.1 KNZ72349.1 - 3.7e-22 78.9 0.0 4.6e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ72349.1 - 0.086 12.3 0.1 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) DUF1623 PF07785.6 KNZ72350.1 - 0.17 11.8 1.6 0.45 10.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1623) Proho_convert PF12177.3 KNZ72350.1 - 2.3 7.8 4.5 1.4 8.5 0.1 2.6 3 0 0 3 3 3 0 Prohormone convertase enzyme Pkinase PF00069.20 KNZ72354.1 - 1e-11 44.5 0.0 6.3e-11 41.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72354.1 - 0.017 14.1 0.1 0.04 12.9 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase DUF3488 PF11992.3 KNZ72355.1 - 0.21 10.1 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Ank_2 PF12796.2 KNZ72356.1 - 1.3e-34 118.3 1.6 5.9e-16 58.5 0.1 3.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ72356.1 - 9.2e-19 66.2 3.9 8.4e-06 25.3 0.1 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KNZ72356.1 - 3.9e-18 65.4 6.1 2.3e-10 40.7 0.1 4.3 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ72356.1 - 3e-17 60.9 4.6 5.8e-05 22.9 0.0 6.3 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 KNZ72356.1 - 4.2e-17 61.7 2.4 1.9e-06 27.9 0.0 4.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Phage_GP20 PF06810.6 KNZ72357.1 - 0.11 11.9 7.0 0.11 11.9 0.3 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 FCH PF00611.18 KNZ72358.1 - 2e-19 69.5 0.5 5.5e-19 68.1 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF2388 PF09498.5 KNZ72358.1 - 0.12 12.0 1.7 1.3 8.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) DUF2411 PF10304.4 KNZ72358.1 - 0.12 11.9 0.2 0.34 10.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) IncA PF04156.9 KNZ72358.1 - 2.3 7.7 10.4 1.4 8.4 2.8 2.2 1 1 0 2 2 2 0 IncA protein Cwf_Cwc_15 PF04889.7 KNZ72361.1 - 2e-72 243.8 23.7 2.9e-72 243.3 16.4 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 KNZ72361.1 - 0.0012 18.2 21.5 0.0015 17.8 14.9 1.2 1 0 0 1 1 1 1 SDA1 TFIIF_alpha PF05793.7 KNZ72361.1 - 0.09 11.1 23.7 0.14 10.5 16.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SGT1 PF07093.6 KNZ72361.1 - 0.14 10.5 13.9 0.15 10.3 9.6 1.1 1 0 0 1 1 1 0 SGT1 protein Daxx PF03344.10 KNZ72361.1 - 0.19 10.1 20.4 0.21 10.0 14.1 1.1 1 0 0 1 1 1 0 Daxx Family DUF506 PF04720.7 KNZ72361.1 - 0.22 11.1 7.7 0.39 10.3 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Rhabdo_ncap PF00945.13 KNZ72361.1 - 0.28 9.7 7.6 0.35 9.4 5.3 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Dsh_C PF12316.3 KNZ72361.1 - 0.35 10.9 3.1 0.18 11.8 0.4 1.6 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Nop14 PF04147.7 KNZ72361.1 - 0.48 8.2 26.8 0.57 8.0 18.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KNZ72361.1 - 1.8 6.5 22.6 2.7 5.9 15.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 KNZ72361.1 - 3.4 5.2 9.5 3.9 5.0 6.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rep_4 PF05797.6 KNZ72361.1 - 4.3 5.9 10.7 6.1 5.4 7.4 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) DUF2167 PF09935.4 KNZ72361.1 - 4.7 5.9 11.5 0.18 10.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) Astro_capsid PF03115.9 KNZ72361.1 - 5.4 5.1 8.5 6.6 4.8 5.9 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Smac_DIABLO PF09057.5 KNZ72361.1 - 7.6 5.5 8.3 0.14 11.2 0.4 1.9 1 1 0 2 2 2 0 Second Mitochondria-derived Activator of Caspases PseudoU_synth_2 PF00849.17 KNZ72362.1 - 1.6e-26 93.1 0.0 2.3e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase F-box PF00646.28 KNZ72363.1 - 2.4 7.9 8.9 6.2 6.6 0.7 3.2 3 0 0 3 3 3 0 F-box domain MoeZ_MoeB PF05237.8 KNZ72364.1 - 6.3e-26 89.7 0.1 2e-25 88.1 0.1 1.9 2 0 0 2 2 2 1 MoeZ/MoeB domain ThiF PF00899.16 KNZ72364.1 - 1.6e-14 53.8 0.0 2.6e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.15 KNZ72364.1 - 4.6e-09 36.6 0.0 8.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Aminotran_5 PF00266.14 KNZ72366.1 - 1.6e-27 96.2 0.0 6.3e-27 94.2 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KNZ72366.1 - 0.033 13.3 0.0 0.063 12.4 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase p450 PF00067.17 KNZ72367.1 - 8.3e-73 245.4 0.0 2.5e-72 243.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Uso1_p115_head PF04869.9 KNZ72368.1 - 3.6e-45 154.0 0.0 3.4e-44 150.8 0.0 2.6 3 1 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 KNZ72368.1 - 2.8e-10 40.2 19.6 5.7e-10 39.2 13.6 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.6 KNZ72368.1 - 0.0099 14.5 9.6 0.016 13.9 6.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein YscO PF07321.7 KNZ72368.1 - 0.031 14.0 12.4 0.059 13.1 8.6 1.4 1 0 0 1 1 1 0 Type III secretion protein YscO Cnd1 PF12717.2 KNZ72368.1 - 0.1 12.4 2.3 0.23 11.2 0.1 2.7 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 FlxA PF14282.1 KNZ72368.1 - 0.11 12.4 15.6 0.22 11.5 10.8 1.5 1 0 0 1 1 1 0 FlxA-like protein HEAT_2 PF13646.1 KNZ72368.1 - 0.16 12.2 5.4 1.1 9.6 0.0 4.1 3 1 2 5 5 4 0 HEAT repeats Seryl_tRNA_N PF02403.17 KNZ72368.1 - 0.26 11.3 13.8 0.14 12.1 7.5 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2570 PF10828.3 KNZ72368.1 - 0.36 10.4 6.0 1.1 8.8 4.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Peptidase_C65 PF10275.4 KNZ72368.1 - 0.39 10.0 6.2 9 5.5 3.6 2.7 3 0 0 3 3 3 0 Peptidase C65 Otubain FH2 PF02181.18 KNZ72368.1 - 0.41 9.4 10.8 0.68 8.7 7.5 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain IncA PF04156.9 KNZ72368.1 - 0.41 10.2 12.5 0.82 9.2 8.7 1.5 1 0 0 1 1 1 0 IncA protein DUF3818 PF12825.2 KNZ72368.1 - 1.1 7.8 9.0 0.24 10.0 3.8 1.6 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) Macoilin PF09726.4 KNZ72368.1 - 1.9 6.6 10.9 2.9 6.0 7.6 1.2 1 0 0 1 1 1 0 Transmembrane protein TBPIP PF07106.8 KNZ72368.1 - 2.1 7.8 16.3 6.2 6.3 10.7 1.9 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 KNZ72368.1 - 5.3 5.8 10.1 8.7 5.1 7.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 KNZ72368.1 - 6.7 7.1 8.4 15 5.9 5.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Atg14 PF10186.4 KNZ72370.1 - 0.037 12.9 4.2 0.075 11.9 2.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 KNZ72370.1 - 0.058 13.2 9.7 0.12 12.1 3.2 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF342 PF03961.8 KNZ72370.1 - 0.39 9.0 3.3 2.2 6.5 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 KNZ72370.1 - 0.63 9.6 8.1 1 9.0 2.3 2.2 2 0 0 2 2 2 0 Mnd1 family IncA PF04156.9 KNZ72370.1 - 0.67 9.5 7.8 0.36 10.3 3.3 2.1 2 0 0 2 2 2 0 IncA protein CENP-Q PF13094.1 KNZ72370.1 - 0.79 9.7 8.9 0.77 9.7 3.9 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit MscS_porin PF12795.2 KNZ72370.1 - 4.8 6.4 16.5 0.014 14.6 3.1 2.6 4 0 0 4 4 4 0 Mechanosensitive ion channel porin domain zf-RVT PF13966.1 KNZ72373.1 - 0.0013 19.0 0.9 0.0021 18.3 0.6 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DAN PF03045.10 KNZ72373.1 - 0.029 13.7 0.3 0.04 13.3 0.2 1.2 1 0 0 1 1 1 0 DAN domain RNase_H PF00075.19 KNZ72374.1 - 1.4e-13 51.3 0.1 1.8e-13 50.9 0.1 1.1 1 0 0 1 1 1 1 RNase H RNase_H PF00075.19 KNZ72377.1 - 2.7e-06 27.7 0.1 3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 RNase H DUF3819 PF12842.2 KNZ72377.1 - 0.079 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) DUF2798 PF11391.3 KNZ72378.1 - 0.017 14.8 1.1 0.048 13.4 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) Ank_3 PF13606.1 KNZ72379.1 - 8.3e-14 50.3 0.2 0.0001 22.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KNZ72379.1 - 1.5e-13 50.4 0.6 6.3e-05 23.0 0.1 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KNZ72379.1 - 9.2e-13 48.3 0.2 9.3e-06 25.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNZ72379.1 - 3.4e-10 40.1 0.1 8.5e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KNZ72379.1 - 6.4e-10 38.3 3.6 0.00015 21.4 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat MT PF12777.2 KNZ72379.1 - 0.086 11.5 0.3 0.12 11.0 0.2 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor IKI3 PF04762.7 KNZ72380.1 - 7.2e-254 844.8 0.4 1.2e-251 837.4 0.3 2.1 1 1 0 1 1 1 1 IKI3 family Clathrin PF00637.15 KNZ72380.1 - 0.16 11.5 1.4 0.79 9.3 0.0 2.6 2 1 0 2 2 2 0 Region in Clathrin and VPS DUF2361 PF10153.4 KNZ72381.1 - 4.5e-30 104.1 13.4 8.1e-30 103.3 9.3 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) Tropomyosin_1 PF12718.2 KNZ72381.1 - 0.0081 16.0 9.4 0.014 15.2 6.5 1.5 1 0 0 1 1 1 1 Tropomyosin like Peptidase_S64 PF08192.6 KNZ72381.1 - 0.19 10.0 3.6 0.25 9.6 2.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 FAD_binding_4 PF01565.18 KNZ72382.1 - 1.2e-12 47.5 0.2 8.2e-05 22.0 0.1 3.0 2 1 0 2 2 2 2 FAD binding domain BBE PF08031.7 KNZ72382.1 - 4e-07 29.8 0.0 8.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KNZ72382.1 - 0.023 13.8 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding ALO PF04030.9 KNZ72382.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Glyco_hydro_3 PF00933.16 KNZ72384.1 - 1.2e-56 191.8 0.0 1.7e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KNZ72384.1 - 1.1e-54 185.3 0.0 1.7e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KNZ72384.1 - 2e-21 75.6 0.8 4e-21 74.7 0.6 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PEP_mutase PF13714.1 KNZ72385.1 - 6.9e-42 143.2 4.4 1.7e-41 141.9 3.0 1.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KNZ72385.1 - 1.2e-20 73.2 0.7 1.8e-20 72.6 0.5 1.2 1 0 0 1 1 1 1 Isocitrate lyase family HSP70 PF00012.15 KNZ72389.1 - 3.2e-39 134.3 0.1 3.5e-39 134.2 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein RNase_H PF00075.19 KNZ72390.1 - 0.00055 20.2 0.1 0.0016 18.7 0.0 1.7 2 0 0 2 2 2 1 RNase H UBN2_2 PF14227.1 KNZ72391.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KNZ72391.1 - 0.16 11.9 3.8 0.64 10.0 2.7 2.0 1 0 0 1 1 1 0 Zinc knuckle Patatin PF01734.17 KNZ72392.1 - 4.6e-10 39.7 0.0 1.7e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.17 KNZ72393.1 - 4.4e-07 29.0 0.5 5.3e-06 25.4 0.0 2.0 1 1 1 2 2 2 2 NB-ARC domain TPR_12 PF13424.1 KNZ72394.1 - 1.4e-58 194.7 3.5 3e-13 49.4 0.1 4.3 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ72394.1 - 6.2e-44 146.7 0.0 1e-08 34.8 0.0 6.0 6 0 0 6 6 6 6 Tetratricopeptide repeat DUF4404 PF14357.1 KNZ72394.1 - 4.2e-09 36.6 4.9 0.003 17.9 0.2 4.2 1 1 3 4 4 4 2 Domain of unknown function (DUF4404) TPR_16 PF13432.1 KNZ72394.1 - 5.2e-09 36.5 0.1 0.11 13.2 0.0 3.6 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ72394.1 - 6.7e-09 35.0 4.7 0.42 10.6 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ72394.1 - 6.1e-08 32.2 0.0 1.5 9.2 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ72394.1 - 3.6e-05 23.2 3.8 13 5.8 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KNZ72394.1 - 0.00012 22.1 0.0 13 6.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ72394.1 - 0.00062 20.0 2.8 0.83 10.0 0.0 3.6 2 1 2 4 4 4 1 Tetratricopeptide repeat MRP-S32 PF10210.4 KNZ72394.1 - 0.0011 19.1 0.6 3.4 8.0 0.0 3.6 2 1 2 4 4 4 1 Mitochondrial 28S ribosomal protein S32 TPR_1 PF00515.23 KNZ72394.1 - 0.0044 16.5 1.8 5.2 6.8 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ72394.1 - 0.0089 15.7 0.6 1.8 8.5 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ72394.1 - 0.011 16.2 5.1 8.5 7.3 0.0 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat STAG PF08514.6 KNZ72394.1 - 0.036 13.7 3.5 3.7 7.2 0.1 3.4 2 1 2 4 4 4 0 STAG domain DUF3366 PF11846.3 KNZ72394.1 - 0.1 12.4 0.3 5.1 6.9 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3366) DUF3848 PF12959.2 KNZ72394.1 - 0.13 12.2 0.3 1.7 8.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3848) APH PF01636.18 KNZ72396.1 - 1.7e-06 27.9 0.7 2.8e-05 23.9 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KNZ72396.1 - 0.0026 16.8 0.0 0.0047 16.0 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KNZ72396.1 - 0.0039 16.7 0.0 0.0079 15.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KNZ72396.1 - 0.023 13.8 0.0 0.055 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain NB-ARC PF00931.17 KNZ72399.1 - 0.054 12.3 0.0 0.063 12.1 0.0 1.0 1 0 0 1 1 1 0 NB-ARC domain APH PF01636.18 KNZ72400.1 - 6.8e-06 25.9 1.8 0.00032 20.4 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ72400.1 - 0.023 14.2 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Asp_protease_2 PF13650.1 KNZ72404.1 - 0.00014 22.2 0.0 0.00015 22.1 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease DUF4470 PF14737.1 KNZ72407.1 - 1.3e-21 76.1 0.1 2.3e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 KNZ72407.1 - 0.0001 22.0 7.1 0.00024 20.9 4.9 1.6 1 0 0 1 1 1 1 MYND finger FANCI_S4 PF14678.1 KNZ72407.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 4 AMP-binding PF00501.23 KNZ72408.1 - 1.1e-36 126.1 0.0 8e-36 123.3 0.0 1.9 1 1 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KNZ72408.1 - 2.5e-21 75.7 0.0 3.7e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KNZ72408.1 - 0.00028 20.4 0.0 0.00047 19.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KNZ72408.1 - 0.0017 18.5 0.1 0.0057 16.8 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site DUF4470 PF14737.1 KNZ72409.1 - 3e-05 23.6 0.0 7.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Flavin_Reduct PF01613.13 KNZ72410.1 - 5.2e-19 68.6 0.0 6.1e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain PNPOx_C PF10590.4 KNZ72411.1 - 0.041 13.3 0.3 0.14 11.6 0.1 1.8 2 0 0 2 2 2 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Ribosomal_L35Ae PF01247.13 KNZ72412.1 - 0.03 14.1 0.1 0.032 14.0 0.0 1.2 1 1 0 1 1 1 0 Ribosomal protein L35Ae Apo-CIII PF05778.7 KNZ72412.1 - 0.041 13.2 0.2 0.075 12.4 0.0 1.5 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) Pyr_redox_3 PF13738.1 KNZ72413.1 - 3.4e-18 66.4 0.1 3.5e-17 63.1 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KNZ72413.1 - 3.5e-14 51.8 0.3 8.9e-13 47.2 0.2 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KNZ72413.1 - 5.3e-11 42.0 0.0 6.1e-08 31.9 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KNZ72413.1 - 2.5e-09 37.3 0.0 0.00021 21.2 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ72413.1 - 1e-08 35.0 0.1 9.8e-08 31.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KNZ72413.1 - 1.8e-05 23.8 3.2 0.019 13.8 0.1 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KNZ72413.1 - 7.2e-05 22.6 5.3 0.083 12.6 0.0 4.1 3 2 0 4 4 4 2 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 KNZ72413.1 - 0.0033 16.5 0.0 0.0069 15.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KNZ72413.1 - 0.0041 17.4 2.9 1.3 9.5 0.1 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KNZ72413.1 - 0.0048 15.8 0.0 0.013 14.4 0.0 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KNZ72413.1 - 0.016 14.3 0.3 0.075 12.1 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 KNZ72413.1 - 0.074 13.1 0.1 0.73 9.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KNZ72413.1 - 0.15 10.8 2.5 1.5 7.5 0.0 2.8 3 1 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KNZ72414.1 - 3.7e-22 79.3 0.0 6.6e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KNZ72414.1 - 1.1e-15 56.8 0.2 1.9e-15 56.0 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KNZ72414.1 - 1.1e-11 44.5 0.2 3.5e-10 39.7 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KNZ72414.1 - 1.3e-10 40.7 0.0 1.3e-09 37.5 0.0 2.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KNZ72414.1 - 2.8e-09 37.1 0.0 0.00032 20.6 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNZ72414.1 - 3.2e-06 26.9 0.2 0.0065 16.2 0.0 4.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KNZ72414.1 - 3.3e-06 26.2 0.1 0.0054 15.6 0.0 3.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KNZ72414.1 - 0.00011 22.4 0.8 0.59 10.5 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KNZ72414.1 - 0.00055 19.1 0.3 0.009 15.1 0.0 2.5 3 0 0 3 3 3 1 Thi4 family 2-Hacid_dh_C PF02826.14 KNZ72414.1 - 0.0039 16.3 0.2 0.012 14.7 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KNZ72414.1 - 0.0048 17.1 0.0 3.9 7.7 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KNZ72414.1 - 0.011 14.7 0.1 0.46 9.3 0.0 2.2 1 1 1 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 KNZ72414.1 - 0.018 13.9 0.0 4 6.1 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KNZ72414.1 - 0.026 13.0 0.5 0.17 10.3 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein SLAIN PF15301.1 KNZ72415.1 - 6.9 5.7 8.2 12 4.9 5.7 1.5 1 1 0 1 1 1 0 SLAIN motif-containing family Glyco_hydro_16 PF00722.16 KNZ72418.1 - 3.7e-14 52.4 7.3 3.1e-13 49.4 4.2 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Adaptin_N PF01602.15 KNZ72419.1 - 1.5e-82 277.6 13.0 2.2e-68 230.8 5.7 3.0 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 KNZ72419.1 - 1.4e-05 25.2 0.1 0.21 11.9 0.0 4.3 2 1 3 5 5 5 3 HEAT repeats Cnd1 PF12717.2 KNZ72419.1 - 0.0022 17.8 0.3 0.085 12.7 0.2 3.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Helitron_like_N PF14214.1 KNZ72420.1 - 3.6e-63 212.6 0.3 8.2e-63 211.4 0.1 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 KNZ72420.1 - 0.048 12.3 0.0 0.082 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) DUF3296 PF11726.3 KNZ72420.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) PIF1 PF05970.9 KNZ72422.1 - 2.1e-51 174.9 0.1 2.3e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ72422.1 - 0.00088 18.9 0.0 0.0013 18.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KNZ72422.1 - 0.0042 16.6 0.2 0.011 15.2 0.1 1.7 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KNZ72422.1 - 0.032 14.3 0.1 0.15 12.2 0.1 1.9 1 1 0 1 1 1 0 RNA helicase Pyr_redox_3 PF13738.1 KNZ72424.1 - 1.4e-20 74.1 0.0 2.5e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KNZ72424.1 - 5e-15 54.7 0.0 1.1e-14 53.5 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KNZ72424.1 - 7.1e-11 41.9 3.5 9.1e-11 41.6 0.0 2.7 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KNZ72424.1 - 3.8e-10 39.2 0.0 4.3e-07 29.1 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KNZ72424.1 - 7e-08 32.5 0.0 0.0032 17.3 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KNZ72424.1 - 3.9e-07 29.3 0.6 0.0014 17.6 0.0 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KNZ72424.1 - 3.8e-06 26.7 0.3 0.0017 18.1 0.0 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KNZ72424.1 - 2.7e-05 23.3 0.1 0.00025 20.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KNZ72424.1 - 6.8e-05 23.1 1.3 0.22 11.9 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KNZ72424.1 - 0.0022 17.1 0.1 0.0054 15.9 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 KNZ72424.1 - 0.0052 15.7 0.0 3 6.6 0.0 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_7 PF13241.1 KNZ72424.1 - 0.014 15.6 0.0 4.7 7.5 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KNZ72424.1 - 0.019 13.8 0.0 0.054 12.3 0.0 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 KNZ72424.1 - 0.028 12.9 0.7 0.1 11.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 KNZ72424.1 - 0.057 12.2 0.0 0.098 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 KNZ72424.1 - 0.1 12.7 0.2 6.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase APH PF01636.18 KNZ72425.1 - 0.00058 19.6 0.1 0.00069 19.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ72425.1 - 0.0012 18.0 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KNZ72425.1 - 0.0041 16.2 0.1 0.009 15.0 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AICARFT_IMPCHas PF01808.13 KNZ72428.1 - 1.1e-109 366.3 0.0 1.4e-109 366.0 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KNZ72428.1 - 1.6e-24 85.6 0.0 3e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain HD_3 PF13023.1 KNZ72429.1 - 2.3e-26 92.5 0.7 2.7e-26 92.2 0.5 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 KNZ72429.1 - 1.1e-06 28.6 0.4 1.8e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 HD domain Tri3 PF07428.6 KNZ72429.1 - 0.11 11.1 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 zf-C2H2 PF00096.21 KNZ72430.1 - 4.2e-11 42.5 7.1 5.7e-05 23.2 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ72430.1 - 4.6e-08 32.8 5.5 0.00076 19.6 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KNZ72430.1 - 1.5e-06 28.2 2.0 1.5e-06 28.2 1.4 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KNZ72430.1 - 0.08 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger MMR_HSR1 PF01926.18 KNZ72432.1 - 3.6e-13 49.4 0.0 5.2e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KNZ72432.1 - 0.00064 19.0 0.0 0.00092 18.5 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KNZ72432.1 - 0.0028 17.4 0.0 0.17 11.7 0.0 2.1 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 KNZ72432.1 - 0.049 12.7 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Tmemb_170 PF10190.4 KNZ72433.1 - 0.019 14.9 1.2 0.021 14.8 0.1 1.5 2 0 0 2 2 2 0 Putative transmembrane protein 170 Rax2 PF12768.2 KNZ72433.1 - 0.071 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF2892 PF11127.3 KNZ72433.1 - 8.6 6.2 7.7 39 4.1 5.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2892) TEA PF01285.13 KNZ72434.1 - 1.4e-11 44.2 0.0 2.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 TEA/ATTS domain family DUF605 PF04652.11 KNZ72434.1 - 9 5.5 8.2 13 5.0 5.7 1.2 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 KNZ72435.1 - 2.6e-39 131.6 14.5 1.3e-10 40.7 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KNZ72435.1 - 0.00085 19.0 0.1 0.51 10.0 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KNZ72435.1 - 0.0011 17.1 5.1 0.013 13.6 1.5 2.5 1 1 2 3 3 3 3 Nucleoporin Nup120/160 SGL PF08450.7 KNZ72435.1 - 0.014 14.8 0.1 0.11 11.8 0.0 2.2 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Kelch_6 PF13964.1 KNZ72435.1 - 0.038 14.1 0.1 1.7 8.9 0.1 2.8 2 0 0 2 2 2 0 Kelch motif RabGAP-TBC PF00566.13 KNZ72436.1 - 1.3e-50 171.8 0.0 2.1e-50 171.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_8 PF13833.1 KNZ72436.1 - 3.7e-06 26.4 0.6 0.012 15.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 KNZ72436.1 - 3.9e-05 23.7 1.2 0.0012 18.9 0.3 3.4 2 1 1 3 3 3 1 EF-hand domain pair GRAM PF02893.15 KNZ72436.1 - 0.00013 21.4 0.0 0.00032 20.1 0.0 1.7 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.1 KNZ72436.1 - 0.00032 20.3 5.0 0.0045 16.7 0.1 3.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 KNZ72436.1 - 0.00037 19.5 2.9 0.0011 18.0 0.0 3.1 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.4 KNZ72436.1 - 0.099 12.6 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region XH PF03469.9 KNZ72438.1 - 0.035 13.7 0.4 1 8.9 0.0 2.1 1 1 1 2 2 2 0 XH domain 2-oxoacid_dh PF00198.18 KNZ72440.1 - 5.9e-49 166.4 0.0 1.2e-48 165.4 0.0 1.5 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KNZ72440.1 - 1.3e-17 63.1 0.1 2.4e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KNZ72440.1 - 1.4e-10 40.6 0.6 2.7e-10 39.7 0.4 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KNZ72440.1 - 0.0045 16.6 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_2 PF12700.2 KNZ72440.1 - 0.069 12.2 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein HlyD_3 PF13437.1 KNZ72440.1 - 0.072 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 HlyD family secretion protein Abhydrolase_1 PF00561.15 KNZ72441.1 - 3.3e-29 102.0 0.0 2.7e-19 69.6 0.0 2.9 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KNZ72441.1 - 4.5e-10 39.8 1.4 7.4e-08 32.5 1.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.20 KNZ72442.1 - 3.7e-15 56.2 5.1 3.6e-12 46.5 0.9 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KNZ72442.1 - 1.8e-07 30.9 3.6 7.7e-07 28.9 0.7 2.2 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KNZ72442.1 - 4.7e-06 26.5 1.9 5.1e-05 23.1 1.3 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KNZ72442.1 - 4.1e-05 23.6 1.9 0.0011 19.0 1.3 2.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KNZ72442.1 - 0.0018 17.7 0.0 0.24 10.8 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KNZ72442.1 - 0.0043 16.8 0.2 0.014 15.1 0.1 1.9 1 1 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 KNZ72442.1 - 0.014 15.0 0.8 0.089 12.4 0.5 2.0 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Shikimate_DH PF01488.15 KNZ72442.1 - 0.042 13.9 0.1 0.083 12.9 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 KNZ72442.1 - 0.049 12.7 0.2 0.23 10.5 0.0 2.0 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_tran_WecB PF03808.8 KNZ72442.1 - 0.093 12.1 0.0 0.22 10.9 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family CoA_binding_2 PF13380.1 KNZ72442.1 - 0.11 12.6 0.6 0.26 11.4 0.4 1.7 1 1 0 1 1 1 0 CoA binding domain PAPA-1 PF04795.7 KNZ72443.1 - 2.8e-11 43.9 8.2 2.8e-11 43.9 5.7 3.8 3 1 0 3 3 3 1 PAPA-1-like conserved region Nop14 PF04147.7 KNZ72443.1 - 9.1 4.0 29.4 0.94 7.3 8.1 2.0 2 0 0 2 2 2 0 Nop14-like family Sporozoite_P67 PF05642.6 KNZ72443.1 - 9.2 3.9 13.5 2.5 5.8 3.8 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen UbiA PF01040.13 KNZ72446.1 - 1.6e-29 102.9 12.1 2.1e-29 102.5 8.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family RVP_2 PF08284.6 KNZ72446.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease NTF2 PF02136.15 KNZ72447.1 - 8.4e-16 58.4 0.1 1.2e-15 57.9 0.1 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_5 PF13893.1 KNZ72447.1 - 8.9e-08 31.8 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KNZ72447.1 - 2.5e-06 26.9 0.0 4.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ72447.1 - 0.00098 19.0 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Het-C PF07217.6 KNZ72448.1 - 1.2e-185 618.2 0.0 2e-114 383.0 0.0 2.0 2 0 0 2 2 2 2 Heterokaryon incompatibility protein Het-C WD40 PF00400.27 KNZ72451.1 - 1.2e-18 66.1 6.3 3.9e-07 29.7 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat PD40 PF07676.7 KNZ72451.1 - 0.029 14.0 0.3 37 4.1 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF2512 PF10710.4 KNZ72451.1 - 0.15 11.5 1.9 0.33 10.3 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) KAR9 PF08580.5 KNZ72451.1 - 2.3 6.3 6.7 3.5 5.7 4.7 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 HECT_2 PF09814.4 KNZ72452.1 - 3.8e-34 117.9 0.0 6.7e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding SR-25 PF10500.4 KNZ72452.1 - 9.3 5.6 12.4 27 4.1 8.6 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DLH PF01738.13 KNZ72453.1 - 1.3e-18 67.1 0.0 2.3e-18 66.2 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 KNZ72453.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ72453.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KNZ72454.1 - 4.2e-22 78.5 0.1 2.3e-21 76.1 0.1 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KNZ72454.1 - 3.8e-06 26.7 0.0 6.8e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ72454.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ72454.1 - 0.11 12.0 0.0 0.51 9.8 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Homoserine_dh PF00742.14 KNZ72456.1 - 4.8e-39 133.8 0.0 1.3e-38 132.5 0.0 1.7 1 1 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KNZ72456.1 - 7e-17 61.9 0.0 1.5e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain PHB_acc_N PF07879.6 KNZ72456.1 - 0.046 13.4 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain BaxI_1 PF12811.2 KNZ72456.1 - 0.059 12.5 0.3 0.1 11.7 0.2 1.3 1 0 0 1 1 1 0 Bax inhibitor 1 like ADC PF06314.6 KNZ72457.1 - 9.4e-06 25.1 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Histone PF00125.19 KNZ72459.1 - 1.9e-21 75.9 0.2 2.9e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KNZ72459.1 - 3.3e-05 23.8 0.1 3.3e-05 23.8 0.0 1.9 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KNZ72459.1 - 0.00024 21.3 0.0 0.00045 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 KNZ72459.1 - 0.018 13.7 2.6 0.023 13.3 1.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1018 PF06252.7 KNZ72459.1 - 0.032 14.7 0.7 0.044 14.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.6 KNZ72459.1 - 0.072 12.4 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Histone PF00125.19 KNZ72460.1 - 5.1e-26 90.5 0.0 6.3e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KNZ72460.1 - 2.3e-05 24.3 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cys_Met_Meta_PP PF01053.15 KNZ72461.1 - 1.8e-24 85.7 0.0 2.5e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KNZ72461.1 - 6.1e-06 25.4 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II CBS PF00571.23 KNZ72462.1 - 5.1e-20 70.9 0.5 1.9e-06 27.5 0.0 4.4 4 0 0 4 4 4 4 CBS domain CNH PF00780.17 KNZ72463.1 - 1.1e-12 47.9 0.0 1.9e-12 47.1 0.0 1.3 1 1 0 1 1 1 1 CNH domain SKG6 PF08693.5 KNZ72464.1 - 0.029 13.6 0.4 0.029 13.6 0.3 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Bacteriocin_IIc PF10439.4 KNZ72464.1 - 0.78 9.9 8.7 3.1 7.9 5.9 2.2 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Zn_clus PF00172.13 KNZ72465.1 - 1.5e-07 31.2 7.1 2.6e-07 30.4 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KNZ72465.1 - 0.00011 21.1 0.0 0.00018 20.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PPR_2 PF13041.1 KNZ72466.1 - 2.5e-09 36.9 0.0 0.05 13.5 0.0 3.9 3 0 0 3 3 3 3 PPR repeat family PPR_3 PF13812.1 KNZ72466.1 - 8.8e-06 25.6 0.2 1.2 9.5 0.0 5.7 7 0 0 7 7 7 1 Pentatricopeptide repeat domain PPR PF01535.15 KNZ72466.1 - 0.00011 21.8 0.0 3.3 7.8 0.0 4.4 5 0 0 5 5 5 2 PPR repeat Pkinase PF00069.20 KNZ72467.1 - 5.8e-66 222.2 0.0 7.8e-66 221.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72467.1 - 2.9e-30 105.2 0.0 4.9e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ72467.1 - 0.0082 15.8 0.0 0.028 14.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family MMR_HSR1 PF01926.18 KNZ72469.1 - 1.2e-10 41.3 0.0 2.4e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KNZ72469.1 - 0.0027 17.0 0.0 0.0068 15.7 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.1 KNZ72469.1 - 0.0095 16.2 0.1 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ72469.1 - 0.02 15.7 0.1 0.069 13.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain Arf PF00025.16 KNZ72469.1 - 0.02 14.1 0.0 0.082 12.1 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_29 PF13555.1 KNZ72469.1 - 0.035 13.6 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.8 KNZ72469.1 - 0.043 12.6 0.0 0.072 11.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.1 KNZ72469.1 - 0.057 13.4 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.22 KNZ72469.1 - 0.096 12.1 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 KNZ72469.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF258 PF03193.11 KNZ72469.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KNZ72469.1 - 0.26 11.1 2.3 0.37 10.6 0.0 2.3 3 0 0 3 3 3 0 Dynamin family DUF202 PF02656.10 KNZ72470.1 - 3e-13 49.8 0.6 3e-13 49.8 0.4 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF2512 PF10710.4 KNZ72470.1 - 0.039 13.4 0.6 0.061 12.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) DUF347 PF03988.7 KNZ72470.1 - 0.35 10.7 4.1 0.89 9.4 0.3 2.6 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) zf-C3HC4_3 PF13920.1 KNZ72471.1 - 7.5e-12 44.7 4.8 4.9e-10 38.9 1.0 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ72471.1 - 9.5e-07 28.7 4.8 1.6e-06 28.0 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ72471.1 - 4.4e-05 23.0 1.5 0.0002 20.9 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ72471.1 - 0.00076 19.1 2.8 0.0076 15.9 0.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KNZ72471.1 - 0.00081 19.1 7.1 0.012 15.3 5.2 2.4 1 1 1 2 2 2 1 Ring finger domain DUF1644 PF07800.7 KNZ72471.1 - 0.19 11.5 0.9 0.42 10.4 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) Prok-RING_4 PF14447.1 KNZ72471.1 - 7.5 6.1 7.3 1 8.9 0.8 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Ribosomal_L18e PF00828.14 KNZ72472.1 - 3.2e-35 121.3 0.1 4.2e-35 120.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 RNA_pol_L_2 PF13656.1 KNZ72473.1 - 1.2e-25 88.7 0.0 1.6e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KNZ72473.1 - 3.4e-13 48.5 0.0 4.6e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.6 KNZ72473.1 - 0.097 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal ADH_zinc_N PF00107.21 KNZ72474.1 - 6.2e-29 100.1 0.6 1.1e-28 99.3 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ72474.1 - 6e-28 96.7 2.8 1.1e-27 95.9 2.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TOBE_2 PF08402.5 KNZ72474.1 - 0.067 13.1 0.6 0.34 10.9 0.0 2.5 3 0 0 3 3 3 0 TOBE domain DapB_N PF01113.15 KNZ72474.1 - 0.072 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RNA_pol_3_Rpc31 PF11705.3 KNZ72475.1 - 4.1e-29 102.1 33.6 3.7e-28 99.0 23.3 1.9 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.7 KNZ72475.1 - 2.4 5.9 5.6 2.7 5.7 3.9 1.1 1 0 0 1 1 1 0 Nop14-like family RRM_1 PF00076.17 KNZ72476.1 - 1.6e-15 56.4 0.0 3.8e-15 55.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ72476.1 - 7.5e-11 41.8 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KNZ72476.1 - 1.5e-06 28.5 0.9 1.5e-06 28.5 0.6 2.6 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 KNZ72476.1 - 0.031 14.1 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PPTA PF01239.17 KNZ72477.1 - 4.9e-39 130.0 11.3 7e-08 31.5 0.0 5.2 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_16 PF13432.1 KNZ72477.1 - 0.037 14.7 0.7 4.7 8.0 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_20 PF00982.16 KNZ72478.1 - 1.5e-148 495.2 0.0 2.1e-148 494.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KNZ72478.1 - 3.4e-70 235.6 0.0 6.6e-70 234.6 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Lipase_GDSL_3 PF14606.1 KNZ72478.1 - 0.16 11.6 0.0 0.4 10.3 0.0 1.6 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Cnd1 PF12717.2 KNZ72479.1 - 2.2e-63 213.3 3.7 3.5e-59 199.6 0.2 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 KNZ72479.1 - 1.9e-51 174.0 6.4 6.8e-51 172.2 0.0 4.4 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 KNZ72479.1 - 4.5e-08 33.2 4.7 0.048 13.9 0.1 5.6 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.17 KNZ72479.1 - 0.00035 20.4 2.7 4.7 7.5 0.1 6.4 7 0 0 7 7 7 1 HEAT repeat YtzH PF14165.1 KNZ72479.1 - 0.0028 17.8 2.3 0.032 14.4 0.5 3.5 2 1 1 3 3 3 1 YtzH-like protein PIP5K PF01504.13 KNZ72480.1 - 1.4e-87 293.0 0.0 1.9e-87 292.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SR-25 PF10500.4 KNZ72480.1 - 0.37 10.2 6.3 1.2 8.6 4.2 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PP2C PF00481.16 KNZ72481.1 - 4.4e-22 78.6 0.0 4e-21 75.5 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KNZ72481.1 - 0.0022 17.7 0.0 0.67 9.6 0.0 2.4 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Aconitase_B_N PF11791.3 KNZ72481.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Aconitate B N-terminal domain MFS_1 PF07690.11 KNZ72482.1 - 3.6e-29 101.5 22.3 1.1e-27 96.6 13.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ72482.1 - 3.6e-05 22.5 8.5 5.3e-05 21.9 4.8 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_M56 PF05569.6 KNZ72482.1 - 0.16 10.9 1.3 0.42 9.5 0.9 1.8 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF2269 PF10027.4 KNZ72482.1 - 0.88 9.3 15.1 0.031 14.0 5.0 2.4 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) RNase_H PF00075.19 KNZ72484.1 - 0.011 16.1 0.1 0.017 15.4 0.0 1.5 1 0 0 1 1 1 0 RNase H Exo_endo_phos_2 PF14529.1 KNZ72486.1 - 3.5e-06 26.6 0.1 7e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KNZ72486.1 - 0.00094 19.1 0.3 0.0016 18.4 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3275 PF11679.3 KNZ72487.1 - 0.086 12.4 1.3 0.68 9.5 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) RNase_H PF00075.19 KNZ72488.1 - 2e-07 31.4 0.0 3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 RNase H Tetraspannin PF00335.15 KNZ72489.1 - 8.9e-12 44.7 14.0 1.3e-11 44.2 9.7 1.2 1 0 0 1 1 1 1 Tetraspanin family SPC12 PF06645.8 KNZ72489.1 - 0.14 11.9 4.2 0.2 11.4 0.9 2.6 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Methyltransf_2 PF00891.13 KNZ72490.1 - 1.4e-32 112.8 0.0 2.4e-32 112.0 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KNZ72490.1 - 0.00067 19.4 0.1 0.002 17.9 0.0 1.9 1 0 0 1 1 1 1 Dimerisation domain ABC2_membrane PF01061.19 KNZ72491.1 - 4.4e-80 267.7 50.3 3.1e-45 153.9 12.4 3.8 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KNZ72491.1 - 2.3e-39 133.2 1.7 1.4e-28 98.5 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KNZ72491.1 - 4.9e-38 130.5 0.0 6.5e-18 65.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 KNZ72491.1 - 2.9e-12 46.5 0.0 6.7e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KNZ72491.1 - 1.5e-08 34.2 0.0 0.00015 21.2 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KNZ72491.1 - 1e-06 28.9 0.0 0.02 15.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KNZ72491.1 - 5.9e-06 25.5 0.0 1.6e-05 24.1 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 KNZ72491.1 - 2.2e-05 23.6 13.3 2.2e-05 23.6 9.2 4.0 3 2 1 4 4 4 2 ABC-2 family transporter protein AAA_16 PF13191.1 KNZ72491.1 - 4.7e-05 23.4 0.0 0.0015 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KNZ72491.1 - 0.00014 21.4 0.1 0.26 10.7 0.0 3.2 3 0 0 3 3 3 1 FtsK/SpoIIIE family NACHT PF05729.7 KNZ72491.1 - 0.00015 21.4 0.1 0.049 13.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 KNZ72491.1 - 0.00016 21.2 0.4 0.16 11.6 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 KNZ72491.1 - 0.00017 21.0 0.0 0.025 14.0 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KNZ72491.1 - 0.00038 20.3 0.0 0.5 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KNZ72491.1 - 0.00059 19.8 0.2 0.61 9.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.14 KNZ72491.1 - 0.00064 19.0 0.0 0.29 10.3 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KNZ72491.1 - 0.0013 18.2 0.4 0.045 13.2 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.1 KNZ72491.1 - 0.0021 17.7 0.7 0.61 9.8 0.5 2.6 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 KNZ72491.1 - 0.0061 16.2 0.0 1.6 8.3 0.0 2.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 KNZ72491.1 - 0.0069 16.6 0.0 0.63 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KNZ72491.1 - 0.013 14.4 0.3 6.1 5.6 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_10 PF12846.2 KNZ72491.1 - 0.016 14.6 0.1 2.1 7.6 0.2 2.4 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 KNZ72491.1 - 0.022 14.9 0.0 3.7 7.7 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KNZ72491.1 - 0.024 14.1 0.0 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KNZ72491.1 - 0.038 14.4 0.0 8.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 KNZ72491.1 - 0.051 13.5 0.0 0.86 9.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KNZ72491.1 - 0.053 13.4 0.4 0.95 9.4 0.0 2.7 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KNZ72491.1 - 0.067 14.0 0.0 1.1 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KNZ72491.1 - 0.07 12.6 0.2 1.4 8.3 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KNZ72491.1 - 0.12 12.3 0.0 0.98 9.3 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Septin PF00735.13 KNZ72491.1 - 0.12 11.3 0.0 3.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Septin RNA_helicase PF00910.17 KNZ72491.1 - 0.12 12.5 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.1 KNZ72491.1 - 0.17 12.2 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 KNZ72491.1 - 0.21 11.0 0.4 7.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 KNZ72491.1 - 0.25 10.4 0.0 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.1 KNZ72491.1 - 0.33 10.5 0.3 18 4.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KNZ72491.1 - 0.36 10.5 0.1 17 5.0 0.1 2.7 3 0 0 3 3 3 0 NTPase AAA_15 PF13175.1 KNZ72491.1 - 0.42 9.6 0.0 3.3 6.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain MAM33 PF02330.11 KNZ72493.1 - 7.2e-17 61.8 0.5 2.8e-13 50.0 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial glycoprotein Aldedh PF00171.17 KNZ72494.1 - 4.6e-84 282.4 0.0 5.7e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PhzC-PhzF PF02567.11 KNZ72495.1 - 1.6e-41 142.4 0.2 1.8e-41 142.2 0.1 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DAP_epimerase PF01678.14 KNZ72495.1 - 0.0057 16.5 0.0 0.23 11.4 0.0 2.5 2 1 0 2 2 2 1 Diaminopimelate epimerase Apolipoprotein PF01442.13 KNZ72496.1 - 2.3e-05 24.0 2.7 0.00099 18.6 0.5 2.5 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain Perilipin PF03036.11 KNZ72496.1 - 6e-05 22.0 10.0 0.0019 17.1 0.0 3.0 1 1 1 2 2 2 2 Perilipin family PLC-beta_C PF08703.5 KNZ72496.1 - 0.0038 16.9 0.3 1.3 8.7 0.0 2.6 2 1 0 2 2 2 2 PLC-beta C terminal Herpes_UL92 PF03048.9 KNZ72496.1 - 0.16 11.5 1.1 12 5.3 0.1 2.3 1 1 1 2 2 2 0 UL92 family WXG100 PF06013.7 KNZ72496.1 - 0.16 11.9 4.9 0.75 9.8 0.8 2.8 2 1 0 2 2 2 0 Proteins of 100 residues with WXG HisKA_3 PF07730.8 KNZ72496.1 - 0.54 10.6 4.7 19 5.7 0.0 4.2 3 2 1 5 5 5 0 Histidine kinase DUF1769 PF08588.5 KNZ72498.1 - 4.4e-15 55.3 0.1 1.6e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) Autophagy_Cterm PF10381.4 KNZ72498.1 - 0.1 11.7 0.1 0.18 10.9 0.1 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal G-alpha PF00503.15 KNZ72499.1 - 1.5e-122 409.0 2.7 1.8e-122 408.8 1.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KNZ72499.1 - 5e-15 55.1 0.1 2.3e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KNZ72499.1 - 0.0011 18.1 0.1 1.4 7.9 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KNZ72499.1 - 0.024 15.1 0.1 1.1 9.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 KNZ72499.1 - 0.062 12.8 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KNZ72499.1 - 0.12 11.8 0.0 7.9 5.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Aldo_ket_red PF00248.16 KNZ72501.1 - 5.6e-58 195.9 0.1 7e-58 195.6 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Copper-fist PF00649.13 KNZ72502.1 - 1.6e-13 49.5 1.4 1.6e-13 49.5 1.0 2.9 1 1 1 2 2 2 2 Copper fist DNA binding domain Ank_2 PF12796.2 KNZ72503.1 - 1.2e-22 80.0 0.4 2.5e-11 43.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ72503.1 - 1.6e-17 62.3 0.7 5.4e-06 25.9 0.2 5.7 4 1 1 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 KNZ72503.1 - 3.3e-15 54.6 0.4 0.00034 20.5 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KNZ72503.1 - 1.7e-14 53.8 0.1 6.1e-07 29.7 0.1 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KNZ72503.1 - 3e-13 49.5 0.8 2.9e-05 24.1 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Bd3614-deam PF14439.1 KNZ72503.1 - 0.085 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase Phage-tail_1 PF09097.5 KNZ72504.1 - 0.14 11.6 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Baseplate structural protein, domain 1 UPF0172 PF03665.8 KNZ72505.1 - 2.1e-45 154.6 0.0 2.7e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) YpzG PF14139.1 KNZ72505.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 YpzG-like protein WD40 PF00400.27 KNZ72506.1 - 1.8e-33 113.1 11.3 3e-08 33.2 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KNZ72506.1 - 0.013 14.2 0.0 0.43 9.2 0.0 2.5 2 1 0 2 2 2 0 Nup133 N terminal like PQQ_2 PF13360.1 KNZ72506.1 - 0.034 13.5 0.2 1.9 7.8 0.1 2.4 2 1 1 3 3 3 0 PQQ-like domain Exo70 PF03081.10 KNZ72509.1 - 0.02 13.6 0.0 0.033 12.9 0.0 1.3 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Hexokinase_1 PF00349.16 KNZ72509.1 - 0.072 12.4 0.1 0.12 11.6 0.0 1.4 1 1 0 1 1 1 0 Hexokinase Hormone_4 PF00220.12 KNZ72510.1 - 0.22 11.2 2.3 0.96 9.2 1.6 2.2 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain AA_permease_2 PF13520.1 KNZ72511.1 - 7.1e-36 123.6 33.1 1.5e-35 122.5 22.1 1.8 1 1 1 2 2 2 2 Amino acid permease Fungal_trans PF04082.13 KNZ72512.1 - 8.5e-38 129.7 0.0 1.7e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ72512.1 - 1.2e-06 28.3 13.2 3.1e-06 26.9 9.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sds3 PF08598.6 KNZ72513.1 - 1.1e-16 61.0 1.6 1.1e-16 61.0 1.1 3.0 2 1 0 2 2 2 1 Sds3-like DUF775 PF05603.7 KNZ72515.1 - 7.4e-44 149.6 0.0 9.4e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) VIT1 PF01988.14 KNZ72516.1 - 4.5e-71 238.7 5.2 5.2e-71 238.5 3.6 1.0 1 0 0 1 1 1 1 VIT family HHH_8 PF14716.1 KNZ72516.1 - 0.069 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix domain Terpene_synth_C PF03936.11 KNZ72517.1 - 8.9e-07 28.4 0.5 1.3e-06 27.8 0.4 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TENA_THI-4 PF03070.11 KNZ72517.1 - 0.037 13.7 0.2 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 TENA/THI-4/PQQC family p450 PF00067.17 KNZ72518.1 - 2.9e-35 121.6 0.0 1.2e-21 76.8 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 PNP_UDP_1 PF01048.15 KNZ72519.1 - 2.7e-36 124.7 0.0 3.5e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Plus-3 PF03126.13 KNZ72520.1 - 1.6e-24 86.0 0.1 2.2e-23 82.3 0.0 2.6 1 1 2 3 3 3 1 Plus-3 domain OPT PF03169.10 KNZ72521.1 - 4.5e-156 520.8 38.2 5.1e-156 520.7 26.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Helitron_like_N PF14214.1 KNZ72522.1 - 5.1e-12 45.8 0.4 1e-11 44.8 0.1 1.6 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 KNZ72523.1 - 1.2e-11 44.1 0.1 1.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase DUF2013 PF09431.5 KNZ72524.1 - 1e-43 148.4 0.9 1e-43 148.4 0.6 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2013) CPSase_L_chain PF00289.17 KNZ72526.1 - 1.2e-21 76.9 0.0 5.1e-21 74.8 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D2 PF02786.12 KNZ72526.1 - 1.5e-10 40.7 0.0 2.3e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 KNZ72526.1 - 0.0007 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.1 KNZ72526.1 - 0.00089 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KNZ72526.1 - 0.0086 14.8 0.0 0.0099 14.6 0.0 1.1 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KNZ72526.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KNZ72526.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DDE_1 PF03184.14 KNZ72527.1 - 6.6e-25 87.5 0.0 7.2e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Pet20 PF08692.5 KNZ72527.1 - 0.063 13.2 0.0 0.079 12.8 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial protein Pet20 COesterase PF00135.23 KNZ72528.1 - 1.1e-93 314.8 0.1 1.3e-93 314.5 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ72528.1 - 0.0002 20.9 0.5 0.0048 16.4 0.1 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Anoctamin PF04547.7 KNZ72529.1 - 1.5e-97 327.1 2.9 1.5e-97 327.1 2.0 1.9 2 0 0 2 2 2 1 Calcium-activated chloride channel p450 PF00067.17 KNZ72530.1 - 8.8e-70 235.5 0.0 1.1e-69 235.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro_isomerase PF00160.16 KNZ72531.1 - 1.9e-39 135.3 0.0 4.1e-39 134.2 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rgp1 PF08737.5 KNZ72531.1 - 4.8 6.1 7.7 2.7 6.9 3.3 1.8 2 0 0 2 2 2 0 Rgp1 UQ_con PF00179.21 KNZ72532.1 - 5.2e-22 77.7 0.1 7e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Thymidylate_kin PF02223.12 KNZ72533.1 - 6.4e-43 146.2 0.0 7.4e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 KNZ72533.1 - 0.00063 19.7 0.0 0.00091 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KNZ72533.1 - 0.0024 17.1 0.0 0.0049 16.1 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_14 PF13173.1 KNZ72533.1 - 0.065 13.1 0.0 3.5 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Glyco_hydro_76 PF03663.9 KNZ72534.1 - 6.3e-28 98.1 20.1 4e-26 92.2 13.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 RhoGEF PF00621.15 KNZ72535.1 - 1.3e-34 119.6 0.0 2.1e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 KNZ72535.1 - 0.00011 22.4 0.0 0.00058 20.0 0.0 2.3 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 KNZ72535.1 - 0.023 14.9 0.0 0.55 10.4 0.0 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain Myb_Cef PF11831.3 KNZ72535.1 - 0.039 13.1 0.2 0.08 12.1 0.1 1.5 1 0 0 1 1 1 0 pre-mRNA splicing factor component Pirin PF02678.11 KNZ72537.1 - 3.3e-26 91.2 1.4 5.3e-26 90.5 0.9 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 KNZ72537.1 - 4e-09 35.8 0.5 5.1e-06 25.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KNZ72537.1 - 0.019 14.3 0.3 0.32 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Dyp_perox PF04261.7 KNZ72538.1 - 6.4e-05 21.8 0.1 0.0055 15.4 0.0 3.2 2 1 0 2 2 2 1 Dyp-type peroxidase family Glyco_transf_15 PF01793.11 KNZ72539.1 - 9.1e-62 208.9 3.9 1.1e-61 208.6 2.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DEAD PF00270.24 KNZ72541.1 - 1.8e-45 154.4 0.0 2.1e-44 150.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ72541.1 - 4.3e-27 93.8 0.1 9.8e-27 92.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ72541.1 - 0.00096 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GATA PF00320.22 KNZ72543.1 - 1.7e-09 36.8 5.4 1.7e-08 33.6 3.7 2.2 1 1 0 1 1 1 1 GATA zinc finger BAF1_ABF1 PF04684.8 KNZ72543.1 - 3.1 6.5 15.6 4.9 5.8 10.8 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1365 PF07103.6 KNZ72544.1 - 0.071 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1365) APH PF01636.18 KNZ72545.1 - 7.2e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ72545.1 - 0.0014 17.8 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KNZ72545.1 - 0.057 12.4 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family P4Ha_N PF08336.6 KNZ72546.1 - 0.056 13.2 0.2 0.056 13.2 0.1 2.4 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Exo_endo_phos PF03372.18 KNZ72546.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family APH PF01636.18 KNZ72547.1 - 1.6e-05 24.7 0.1 4.7e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ72547.1 - 0.0072 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF383 PF04063.9 KNZ72549.1 - 5.3e-58 195.7 0.0 1e-57 194.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KNZ72549.1 - 3.8e-17 61.5 0.1 7.8e-17 60.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Borrelia_lipo_1 PF05714.6 KNZ72549.1 - 0.085 11.9 0.1 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein Spt20 PF12090.3 KNZ72551.1 - 7e-33 113.5 4.6 9.5e-33 113.0 0.0 2.6 2 1 0 2 2 2 1 Spt20 family TPR_11 PF13414.1 KNZ72553.1 - 9e-08 31.6 0.3 2.5e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 TPR repeat Fis1_TPR_C PF14853.1 KNZ72553.1 - 0.021 14.6 0.0 0.059 13.2 0.0 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 KNZ72553.1 - 0.027 14.3 0.1 3 7.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_15 PF01793.11 KNZ72554.1 - 4.5e-70 236.2 6.7 7.8e-70 235.4 4.6 1.4 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase HAT PF02184.11 KNZ72554.1 - 4.8e-19 67.7 58.4 1.1e-07 31.5 1.2 13.8 16 1 0 16 16 14 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 KNZ72554.1 - 1.4e-18 65.6 24.6 0.015 15.8 0.0 12.0 6 3 7 13 13 13 5 Tetratricopeptide repeat Suf PF05843.9 KNZ72554.1 - 2.4e-15 57.0 5.3 8.6e-05 22.4 0.0 6.5 3 2 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 KNZ72554.1 - 5.1e-13 49.1 0.8 0.33 11.3 0.0 7.3 4 2 5 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ72554.1 - 5.3e-13 49.2 14.8 0.00047 20.7 0.0 7.9 7 2 2 9 9 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ72554.1 - 6.7e-11 41.2 4.7 0.084 12.8 0.0 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ72554.1 - 1.8e-07 30.7 4.1 0.16 11.6 0.0 5.4 6 1 1 7 7 7 2 TPR repeat TPR_15 PF13429.1 KNZ72554.1 - 1.4e-06 27.5 20.4 0.3 10.1 4.7 5.7 2 2 3 5 5 5 4 Tetratricopeptide repeat SNAP PF14938.1 KNZ72554.1 - 2.7e-06 26.7 2.2 0.0005 19.2 0.1 3.2 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KNZ72554.1 - 1.8e-05 24.6 8.7 0.52 10.2 0.0 6.9 6 3 1 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ72554.1 - 0.00014 21.7 0.0 1.7 9.0 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ72554.1 - 0.00018 21.0 11.0 6 6.9 0.0 7.4 9 0 0 9 9 7 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 KNZ72554.1 - 0.00038 20.2 14.3 0.72 9.6 0.3 6.5 4 2 2 7 7 6 1 Mad3/BUB1 homology region 1 TPR_1 PF00515.23 KNZ72554.1 - 0.001 18.5 0.0 4.6 7.0 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ72554.1 - 0.0031 17.1 0.1 22 5.1 0.0 5.1 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ72554.1 - 0.0054 17.1 9.3 1.2e+02 3.4 0.0 8.1 9 1 0 9 9 7 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 KNZ72554.1 - 0.017 14.8 0.6 0.017 14.8 0.4 5.5 4 3 2 7 7 7 0 U3 small nucleolar RNA-associated protein 6 YlbD_coat PF14071.1 KNZ72554.1 - 0.14 12.1 5.3 11 6.1 2.9 3.4 2 1 0 2 2 2 0 Putative coat protein c-SKI_SMAD_bind PF08782.5 KNZ72554.1 - 0.33 11.0 2.2 2 8.6 0.1 3.2 4 0 0 4 4 4 0 c-SKI Smad4 binding domain WEMBL PF05701.6 KNZ72556.1 - 0.044 12.2 3.8 0.055 11.9 2.6 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Prefoldin PF02996.12 KNZ72556.1 - 0.11 12.0 0.2 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.3 KNZ72556.1 - 0.16 11.6 2.5 0.31 10.7 1.7 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 KNZ72556.1 - 0.66 9.8 4.6 1.4 8.8 2.3 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APH PF01636.18 KNZ72557.1 - 2.6e-06 27.3 0.0 8.1e-06 25.7 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ72557.1 - 0.00054 19.1 0.0 0.0008 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 KNZ72557.1 - 0.0065 16.0 0.0 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase RdRP_2 PF00978.16 KNZ72557.1 - 0.16 10.6 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase adh_short PF00106.20 KNZ72558.1 - 4.7e-24 85.1 0.1 6.7e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ72558.1 - 1.4e-11 44.4 0.0 3.7e-11 43.0 0.0 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KNZ72558.1 - 9.4e-06 25.7 0.0 0.023 14.6 0.0 2.1 2 0 0 2 2 2 2 NADH(P)-binding adh_short_C2 PF13561.1 KNZ72558.1 - 8.2e-05 22.4 0.0 9.8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 KNZ72558.1 - 0.035 12.8 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KNZ72561.1 - 1.9e-11 44.2 0.0 2.4e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ72561.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 KR domain APH PF01636.18 KNZ72562.1 - 1.3e-05 25.0 0.1 4.8e-05 23.2 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ72562.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 KNZ72562.1 - 0.062 12.8 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase RdRP_2 PF00978.16 KNZ72562.1 - 0.14 10.8 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase APH PF01636.18 KNZ72564.1 - 1.8e-05 24.6 0.1 6.4e-05 22.8 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ72564.1 - 0.00043 19.5 0.0 0.0006 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 KNZ72564.1 - 0.058 12.9 0.0 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase RdRP_2 PF00978.16 KNZ72564.1 - 0.12 10.9 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase eIF3g PF12353.3 KNZ72565.1 - 0.00023 21.1 0.6 0.00047 20.0 0.4 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-C2HC5 PF06221.8 KNZ72566.1 - 1.5e-11 43.8 2.9 2.2e-11 43.3 2.0 1.2 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DZR PF12773.2 KNZ72566.1 - 0.67 9.8 4.2 1.3 8.9 2.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon HAUS6_N PF14661.1 KNZ72567.1 - 1.1e-07 31.5 1.3 0.00027 20.3 0.0 3.2 3 0 0 3 3 3 2 HAUS augmin-like complex subunit 6 N-terminus Terpene_synth_C PF03936.11 KNZ72568.1 - 1.2e-05 24.6 0.1 2.3e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.11 KNZ72570.1 - 0.0034 16.6 0.0 0.0077 15.4 0.0 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Amino_oxidase PF01593.19 KNZ72571.1 - 2.6e-74 250.9 0.1 6.2e-72 243.0 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KNZ72571.1 - 2.2e-12 46.8 0.2 5.9e-12 45.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KNZ72571.1 - 0.00018 20.6 0.6 0.00031 19.8 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KNZ72571.1 - 0.00019 20.4 0.1 0.0012 17.8 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ72571.1 - 0.00088 18.2 0.2 0.0012 17.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KNZ72571.1 - 0.001 18.2 0.4 0.0019 17.3 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KNZ72571.1 - 0.0011 19.0 0.7 0.0074 16.3 0.4 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KNZ72571.1 - 0.015 14.8 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 KNZ72571.1 - 0.017 15.5 0.5 0.043 14.2 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KNZ72571.1 - 0.024 13.0 0.1 0.041 12.3 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.15 KNZ72571.1 - 0.047 13.7 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KNZ72571.1 - 0.16 10.8 0.2 0.26 10.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Terpene_synth_C PF03936.11 KNZ72572.1 - 0.0019 17.4 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain PTR2 PF00854.16 KNZ72576.1 - 4.7e-43 147.3 7.0 3.6e-42 144.4 4.9 2.0 1 1 0 1 1 1 1 POT family UBN2_2 PF14227.1 KNZ72580.1 - 8e-14 51.2 0.0 1.1e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ72580.1 - 2.7e-08 33.6 0.0 3.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 KNZ72580.1 - 0.065 12.6 0.9 0.2 11.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) zf-CCHC PF00098.18 KNZ72580.1 - 0.18 11.7 2.4 0.43 10.5 1.7 1.6 1 0 0 1 1 1 0 Zinc knuckle NUDIX PF00293.23 KNZ72582.1 - 9.4e-08 31.7 0.0 2.3e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain DUF4407 PF14362.1 KNZ72583.1 - 0.012 14.6 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) p450 PF00067.17 KNZ72584.1 - 1.8e-61 208.1 0.0 2.4e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DSPc PF00782.15 KNZ72586.1 - 2.6e-40 137.0 0.1 2.5e-30 104.7 0.1 2.5 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KNZ72586.1 - 4.3e-05 22.9 0.0 7.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KNZ72586.1 - 0.0013 18.2 0.1 0.0028 17.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPn PF14671.1 KNZ72586.1 - 0.028 14.3 1.0 3.7 7.5 0.0 2.5 2 1 0 2 2 2 0 Dual specificity protein phosphatase, N-terminal half Myotub-related PF06602.9 KNZ72586.1 - 0.052 12.3 0.0 0.082 11.6 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 KNZ72586.1 - 0.054 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family 7TM_GPCR_Sri PF10327.4 KNZ72586.1 - 0.068 12.1 0.7 1.3 7.9 0.0 2.6 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sri HTH_21 PF13276.1 KNZ72589.1 - 0.0034 17.3 0.0 0.0077 16.2 0.0 1.6 1 0 0 1 1 1 1 HTH-like domain SIR2 PF02146.12 KNZ72590.1 - 5e-23 81.7 0.1 4e-21 75.5 0.1 2.8 1 1 0 1 1 1 1 Sir2 family zf-C2H2 PF00096.21 KNZ72591.1 - 7.4e-05 22.8 13.1 0.00056 20.0 1.4 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KNZ72591.1 - 0.00068 19.7 4.5 0.00068 19.7 3.2 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KNZ72591.1 - 0.013 15.7 22.7 0.014 15.7 1.4 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger RPAP2_Rtr1 PF04181.8 KNZ72591.1 - 0.031 14.3 0.3 0.088 12.9 0.2 1.7 1 0 0 1 1 1 0 Rtr1/RPAP2 family Metallophos PF00149.23 KNZ72592.1 - 5.3e-41 140.2 0.3 7.9e-41 139.6 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Flavoprotein PF02441.14 KNZ72592.1 - 0.044 13.4 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Flavoprotein ABC_tran PF00005.22 KNZ72593.1 - 4.6e-46 156.5 0.0 1.3e-23 83.7 0.0 3.1 3 1 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 KNZ72593.1 - 2.1e-20 72.3 6.4 3.9e-20 71.4 3.5 2.2 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KNZ72593.1 - 4.8e-17 62.8 0.6 0.0032 17.4 0.0 4.5 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KNZ72593.1 - 6.9e-09 35.1 0.4 0.0015 18.0 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KNZ72593.1 - 9.4e-08 32.2 0.2 0.0013 18.8 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KNZ72593.1 - 1.5e-07 31.9 9.2 0.0066 16.7 0.0 4.0 5 0 0 5 5 4 2 AAA domain NACHT PF05729.7 KNZ72593.1 - 5.2e-06 26.2 0.0 0.07 12.7 0.0 2.5 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.14 KNZ72593.1 - 5.3e-06 25.8 2.3 0.64 9.2 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 KNZ72593.1 - 9e-06 26.1 0.0 0.13 12.7 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 KNZ72593.1 - 2e-05 24.1 0.0 0.14 11.5 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 KNZ72593.1 - 2.2e-05 25.2 0.1 0.15 12.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KNZ72593.1 - 8.5e-05 22.7 0.0 0.19 11.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KNZ72593.1 - 0.00018 20.7 0.0 0.052 12.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KNZ72593.1 - 0.00019 20.9 0.1 0.92 8.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 KNZ72593.1 - 0.00041 20.2 0.1 0.55 10.2 0.0 3.1 4 0 0 4 4 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KNZ72593.1 - 0.0005 20.0 0.0 0.055 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KNZ72593.1 - 0.0005 20.3 0.2 1.7 8.9 0.0 3.4 4 1 0 4 4 4 1 AAA domain AAA_10 PF12846.2 KNZ72593.1 - 0.00067 19.1 0.0 0.5 9.7 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain AAA PF00004.24 KNZ72593.1 - 0.0011 19.1 0.0 6.6 6.9 0.0 4.3 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 KNZ72593.1 - 0.0021 17.8 4.2 1 9.1 0.5 3.5 3 1 1 4 4 4 2 Domain of unknown function DUF87 RNA_helicase PF00910.17 KNZ72593.1 - 0.0022 18.1 2.9 3.7 7.7 0.0 3.4 3 0 0 3 3 3 2 RNA helicase AAA_14 PF13173.1 KNZ72593.1 - 0.0026 17.6 0.0 6.1 6.7 0.0 4.3 5 0 0 5 5 5 0 AAA domain AAA_33 PF13671.1 KNZ72593.1 - 0.0038 17.1 0.0 3.3 7.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 KNZ72593.1 - 0.004 16.8 0.4 4.1 7.0 0.0 3.4 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KNZ72593.1 - 0.0041 16.7 0.1 0.58 9.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KNZ72593.1 - 0.0051 16.5 0.1 5 6.8 0.1 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 KNZ72593.1 - 0.0061 16.3 6.2 0.45 10.3 0.0 3.9 2 2 1 3 3 3 1 Dynamin family SbcCD_C PF13558.1 KNZ72593.1 - 0.024 14.5 0.0 5.9 6.8 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 KNZ72593.1 - 0.027 13.9 0.0 2.8 7.3 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DAP3 PF10236.4 KNZ72593.1 - 0.031 13.2 2.5 4.1 6.2 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_19 PF13245.1 KNZ72593.1 - 0.032 13.9 0.0 0.58 9.9 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain NTPase_1 PF03266.10 KNZ72593.1 - 0.064 12.9 3.4 2.4 7.8 0.1 3.2 4 0 0 4 4 4 0 NTPase G-alpha PF00503.15 KNZ72593.1 - 0.49 9.0 4.7 3 6.4 0.1 2.7 2 1 0 2 2 2 0 G-protein alpha subunit ProSAAS PF07259.7 KNZ72594.1 - 0.081 12.4 0.8 0.14 11.7 0.5 1.3 1 0 0 1 1 1 0 ProSAAS precursor UPF0147 PF03685.8 KNZ72596.1 - 0.01 15.6 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) DUF2296 PF10058.4 KNZ72597.1 - 4e-21 74.5 0.5 6.6e-21 73.8 0.4 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DYW_deaminase PF14432.1 KNZ72597.1 - 0.066 13.2 0.4 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 DYW family of nucleic acid deaminases zf-CHY PF05495.7 KNZ72597.1 - 0.066 13.3 0.3 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 KNZ72597.1 - 0.38 10.6 1.9 0.44 10.3 0.6 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 KNZ72597.1 - 0.51 10.1 2.4 2.4 8.0 1.8 1.9 1 1 1 2 2 2 0 PhnA Zinc-Ribbon DSPc PF00782.15 KNZ72598.1 - 2.1e-39 134.1 0.0 1.8e-31 108.4 0.0 3.0 2 1 1 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KNZ72598.1 - 0.00041 19.7 0.0 0.00084 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPn PF14671.1 KNZ72598.1 - 0.024 14.6 0.1 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.1 KNZ72598.1 - 0.1 12.6 0.2 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate HTH_38 PF13936.1 KNZ72600.1 - 5.2e-10 38.7 1.2 9.5e-10 37.8 0.8 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.14 KNZ72600.1 - 0.0056 15.9 0.1 0.009 15.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.1 KNZ72600.1 - 0.0096 15.5 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.2 KNZ72600.1 - 0.021 14.4 0.1 0.056 13.1 0.0 1.7 2 0 0 2 2 2 0 MarR family MarR PF01047.17 KNZ72600.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 MarR family Sigma54_DBD PF04552.8 KNZ72600.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54, DNA binding domain Retrotrans_gag PF03732.12 KNZ72600.1 - 0.13 12.3 0.1 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Sigma70_r4 PF04545.11 KNZ72600.1 - 0.13 11.5 0.9 0.24 10.7 0.6 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.1 KNZ72601.1 - 2.7e-05 23.6 1.4 4.8e-05 22.8 1.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.14 KNZ72601.1 - 0.14 11.4 0.4 0.21 10.9 0.3 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Mnd1 PF03962.10 KNZ72603.1 - 0.0068 16.0 9.4 0.0071 16.0 0.7 2.3 2 0 0 2 2 2 1 Mnd1 family Atrophin-1 PF03154.10 KNZ72603.1 - 0.0081 14.3 0.0 0.012 13.8 0.0 1.1 1 0 0 1 1 1 1 Atrophin-1 family Fmp27_WPPW PF10359.4 KNZ72603.1 - 0.43 8.9 3.7 0.28 9.5 1.2 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Nup54 PF13874.1 KNZ72603.1 - 0.46 10.1 6.3 0.36 10.4 2.3 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Spectrin PF00435.16 KNZ72603.1 - 0.87 9.9 7.7 2.8 8.2 3.8 2.3 2 0 0 2 2 2 0 Spectrin repeat SlyX PF04102.7 KNZ72603.1 - 0.87 9.9 5.1 20 5.6 0.0 3.7 3 1 1 4 4 4 0 SlyX DivIC PF04977.10 KNZ72603.1 - 3.2 7.2 8.7 9.6 5.7 0.7 3.7 3 0 0 3 3 3 0 Septum formation initiator TMCO5 PF14992.1 KNZ72603.1 - 6.4 5.8 12.2 0.42 9.7 4.5 1.8 2 1 1 3 3 3 0 TMCO5 family Tropomyosin_1 PF12718.2 KNZ72604.1 - 0.053 13.3 10.8 0.089 12.6 7.5 1.4 1 0 0 1 1 1 0 Tropomyosin like DUF4226 PF10774.4 KNZ72604.1 - 0.073 13.1 0.9 0.14 12.2 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) Spore_II_R PF09551.5 KNZ72604.1 - 0.11 12.5 0.4 0.23 11.5 0.2 1.5 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) DUF536 PF04394.9 KNZ72604.1 - 6.7 6.5 16.3 2 8.2 8.8 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF536 Aa_trans PF01490.13 KNZ72606.1 - 4.7e-16 58.2 22.2 1e-15 57.2 15.4 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein UBACT PF02134.16 KNZ72606.1 - 0.037 13.6 0.5 0.077 12.5 0.3 1.5 1 0 0 1 1 1 0 Repeat in ubiquitin-activating (UBA) protein Thiolase_N PF00108.18 KNZ72607.1 - 6.5e-06 25.3 0.0 8.2e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Herpes_US9 PF06072.6 KNZ72607.1 - 0.14 12.0 0.3 0.26 11.1 0.2 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 SSF PF00474.12 KNZ72608.1 - 4.2e-24 84.9 35.1 4.2e-24 84.9 24.3 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family DUF2207 PF09972.4 KNZ72608.1 - 0.23 10.0 0.0 0.23 10.0 0.0 3.6 4 1 0 5 5 5 0 Predicted membrane protein (DUF2207) Ferritin_2 PF13668.1 KNZ72609.1 - 5.3e-34 117.1 0.1 8.1e-34 116.5 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Metallophos_2 PF12850.2 KNZ72610.1 - 8.4e-09 35.4 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KNZ72610.1 - 6.5e-08 32.2 5.0 1.4e-07 31.1 3.5 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FA_desaturase PF00487.19 KNZ72611.1 - 6.5e-25 88.0 25.5 6.5e-25 88.0 17.7 1.3 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.3 KNZ72611.1 - 0.00032 20.7 0.1 0.00054 20.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.19 KNZ72612.1 - 8.3e-25 87.6 30.7 1.2e-24 87.1 21.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KNZ72612.1 - 1.4e-05 25.1 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) TBP PF00352.16 KNZ72612.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) DUF2235 PF09994.4 KNZ72614.1 - 4.4e-79 265.7 0.0 6.1e-79 265.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KNZ72614.1 - 0.026 14.2 0.0 0.045 13.5 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 KNZ72615.1 - 8.5e-79 264.6 0.0 2.1e-78 263.3 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KNZ72615.1 - 2.3e-48 165.1 0.0 1.7e-47 162.3 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KNZ72615.1 - 1.3e-38 131.5 0.6 3e-38 130.3 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KNZ72615.1 - 2.5e-24 85.9 0.0 3.9e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 KNZ72615.1 - 1.5e-19 71.1 0.0 1e-18 68.4 0.0 2.5 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 KNZ72615.1 - 7.4e-12 45.3 1.0 2.2e-11 43.8 0.7 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 KNZ72615.1 - 5.4e-11 42.8 1.4 3.5e-09 36.8 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ72615.1 - 2.6e-07 30.5 0.1 0.0059 16.3 0.0 3.5 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KNZ72615.1 - 0.017 14.1 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain TraN PF06986.6 KNZ72616.1 - 2.9 7.2 25.7 0.82 8.9 6.0 2.1 1 1 1 2 2 2 0 Type-1V conjugative transfer system mating pair stabilisation Paramecium_SA PF01508.11 KNZ72616.1 - 6.5 7.0 21.0 1 9.6 2.6 2.6 2 1 1 3 3 3 0 Paramecium surface antigen domain zf-GRF PF06839.7 KNZ72617.1 - 0.31 10.9 3.3 0.88 9.5 2.3 1.8 1 0 0 1 1 1 0 GRF zinc finger CN_hydrolase PF00795.17 KNZ72622.1 - 1.2e-26 93.2 0.0 1.9e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KNZ72622.1 - 1.4e-22 79.7 0.0 9.3e-22 77.0 0.0 2.1 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 KNZ72622.1 - 0.063 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Asparagine synthase Sec6 PF06046.8 KNZ72623.1 - 2.2e-146 488.2 1.9 2.2e-146 488.2 1.3 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec6 HECT PF00632.20 KNZ72623.1 - 0.0064 15.6 0.2 0.013 14.7 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RPN7 PF10602.4 KNZ72623.1 - 0.029 13.7 1.0 0.066 12.5 0.3 1.9 2 0 0 2 2 2 0 26S proteasome subunit RPN7 DUF885 PF05960.6 KNZ72623.1 - 0.099 11.7 10.0 0.3 10.1 0.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF885) FAD_binding_3 PF01494.14 KNZ72624.1 - 1.5e-22 80.1 0.2 1.2e-12 47.5 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KNZ72624.1 - 2.8e-06 26.5 0.0 0.00036 19.5 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.19 KNZ72624.1 - 0.00017 20.6 0.0 0.034 13.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KNZ72624.1 - 0.00018 20.3 0.3 0.0058 15.3 0.1 2.7 3 0 0 3 3 3 1 Tryptophan halogenase SE PF08491.5 KNZ72624.1 - 0.00036 19.4 0.0 0.00054 18.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 KNZ72624.1 - 0.00056 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KNZ72624.1 - 0.0007 18.7 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KNZ72624.1 - 0.0031 17.3 0.0 0.0086 15.8 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KNZ72624.1 - 0.027 14.4 0.2 0.084 12.9 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KNZ72624.1 - 0.032 13.0 0.7 0.061 12.1 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 KNZ72624.1 - 0.036 12.5 0.0 0.076 11.4 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 KNZ72624.1 - 0.042 14.2 0.2 0.37 11.2 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.2 KNZ72625.1 - 0.01 15.5 0.0 0.033 13.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like HAUS4 PF14735.1 KNZ72626.1 - 2.4e-07 30.2 0.8 8.4e-05 21.9 0.0 2.2 1 1 1 2 2 2 2 HAUS augmin-like complex subunit 4 COG5 PF10392.4 KNZ72626.1 - 0.024 14.5 0.9 0.066 13.1 0.6 1.7 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Turandot PF07240.6 KNZ72626.1 - 0.077 12.4 0.0 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot HlyD PF00529.15 KNZ72626.1 - 0.55 9.4 4.6 0.66 9.2 1.8 1.8 1 1 1 2 2 2 0 HlyD family secretion protein Na_H_Exchanger PF00999.16 KNZ72629.1 - 2.2e-53 181.1 28.8 2.8e-53 180.7 19.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Tim17 PF02466.14 KNZ72629.1 - 0.085 12.9 2.4 0.36 10.8 0.1 3.0 3 1 1 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family DUF2649 PF10854.3 KNZ72629.1 - 1.2 9.2 6.2 0.11 12.5 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) SRCR PF00530.13 KNZ72630.1 - 0.15 12.4 1.3 4.1 7.8 0.9 2.6 1 1 0 1 1 1 0 Scavenger receptor cysteine-rich domain Na_H_Exchanger PF00999.16 KNZ72634.1 - 2.2e-54 184.4 22.7 2.9e-54 184.0 15.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Tim17 PF02466.14 KNZ72634.1 - 0.25 11.3 4.8 0.23 11.4 0.2 3.1 3 2 1 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family MNHE PF01899.11 KNZ72634.1 - 3 7.4 10.3 2 8.0 0.6 3.0 3 0 0 3 3 3 0 Na+/H+ ion antiporter subunit rve PF00665.21 KNZ72636.1 - 3.5e-08 33.5 0.0 8.9e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 KNZ72640.1 - 0.013 15.3 0.7 0.036 13.9 0.5 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 KNZ72640.1 - 0.052 13.0 0.3 0.13 11.7 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle YlbD_coat PF14071.1 KNZ72640.1 - 0.15 12.1 1.2 2.4 8.2 0.2 2.7 3 0 0 3 3 3 0 Putative coat protein Na_H_Exchanger PF00999.16 KNZ72641.1 - 1e-53 182.2 29.0 1.4e-53 181.8 20.1 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3112 PF11309.3 KNZ72641.1 - 2.3 7.9 10.4 3e+02 1.0 6.6 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) Spore_YhaL PF14147.1 KNZ72641.1 - 7.5 6.0 7.7 0.41 10.1 0.1 2.9 4 0 0 4 4 4 0 Sporulation protein YhaL Mito_carr PF00153.22 KNZ72644.1 - 4e-31 106.5 9.4 2.2e-18 65.7 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Photo_RC PF00124.14 KNZ72644.1 - 0.067 12.1 1.9 0.07 12.1 0.1 1.7 2 0 0 2 2 2 0 Photosynthetic reaction centre protein DHBP_synthase PF00926.14 KNZ72645.1 - 2.9e-81 271.3 0.0 3.3e-81 271.1 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase PS_Dcarbxylase PF02666.10 KNZ72646.1 - 2.6e-50 170.5 0.0 3.9e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase zf-CCCH PF00642.19 KNZ72646.1 - 7.6e-27 92.4 67.3 7.6e-05 22.2 2.5 8.5 8 0 0 8 8 8 8 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GFO_IDH_MocA PF01408.17 KNZ72646.1 - 1.2e-20 74.1 0.0 3.2e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold zf-C3HC4_4 PF15227.1 KNZ72646.1 - 0.00032 20.4 5.2 0.00093 19.0 3.6 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.1 KNZ72646.1 - 0.003 17.4 74.0 0.06 13.3 2.4 8.3 8 0 0 8 8 8 5 Zinc finger C-x8-C-x5-C-x3-H type zf-RING_UBOX PF13445.1 KNZ72646.1 - 0.0037 16.9 2.0 0.015 15.0 1.4 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KNZ72646.1 - 0.0039 17.1 6.5 0.015 15.3 4.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ72646.1 - 0.0072 16.1 6.8 0.032 14.0 4.7 2.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KNZ72646.1 - 0.021 14.4 3.8 0.06 13.0 2.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 KNZ72646.1 - 0.063 12.9 0.0 0.33 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 KNZ72646.1 - 0.066 12.8 8.1 0.19 11.4 5.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OHCU_decarbox PF09349.5 KNZ72647.1 - 4.3e-26 92.1 0.0 7.2e-26 91.3 0.0 1.4 1 1 0 1 1 1 1 OHCU decarboxylase DnaJ PF00226.26 KNZ72648.1 - 7.4e-22 76.8 1.7 1.8e-21 75.5 1.1 1.7 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 KNZ72648.1 - 0.096 12.1 0.0 0.42 10.0 0.0 2.2 2 1 0 2 2 2 0 A repeated domain in UCH-protein Mit_ribos_Mrp51 PF11709.3 KNZ72648.1 - 0.14 11.3 0.9 0.18 10.9 0.7 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit Hrs_helical PF12210.3 KNZ72648.1 - 0.26 11.5 4.8 1.5 9.1 0.4 3.0 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Pkinase PF00069.20 KNZ72649.1 - 4.6e-62 209.5 0.0 5.8e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72649.1 - 4.7e-30 104.5 0.0 6.2e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ72649.1 - 0.012 15.3 0.1 0.042 13.5 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KNZ72649.1 - 0.046 12.6 0.0 0.074 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-RanBP PF00641.13 KNZ72650.1 - 4.5e-07 28.8 15.6 3.7e-05 22.7 3.3 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 KNZ72650.1 - 7.4e-05 22.2 1.8 0.37 10.3 0.3 2.7 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger Prok-RING_2 PF14445.1 KNZ72650.1 - 0.33 10.9 3.2 3.5 7.6 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 PHD_2 PF13831.1 KNZ72650.1 - 2.9 7.2 6.9 2.3 7.6 0.0 2.7 3 0 0 3 3 3 0 PHD-finger NADH-u_ox-rdase PF10785.4 KNZ72651.1 - 1.3e-33 115.0 0.3 2e-33 114.4 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 KNZ72651.1 - 3.3e-15 55.5 0.0 4.5e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Transferase PF02458.10 KNZ72652.1 - 9e-30 103.4 0.0 4.4e-14 51.7 0.0 2.1 2 0 0 2 2 2 2 Transferase family DPBB_1 PF03330.13 KNZ72653.1 - 4.3e-05 23.4 1.8 4.8e-05 23.2 0.2 1.8 1 1 1 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KNZ72653.1 - 0.068 12.8 0.5 0.14 11.8 0.3 1.6 1 1 0 1 1 1 0 Barwin family zf-DHHC PF01529.15 KNZ72654.1 - 9.3e-23 80.4 1.5 1.4e-22 79.9 1.0 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Med4 PF10018.4 KNZ72655.1 - 6.9e-26 90.8 0.0 8.7e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 IncA PF04156.9 KNZ72655.1 - 0.15 11.6 2.0 0.21 11.1 1.4 1.2 1 0 0 1 1 1 0 IncA protein Ead_Ea22 PF13935.1 KNZ72655.1 - 0.18 12.1 1.4 0.26 11.6 1.0 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein DUF3782 PF12644.2 KNZ72655.1 - 0.34 10.7 1.7 0.61 9.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Voltage_CLC PF00654.15 KNZ72656.1 - 1.2e-83 281.0 23.9 1.2e-83 281.0 16.6 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KNZ72656.1 - 2.4e-05 23.9 0.0 0.019 14.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain DUF2408 PF10303.4 KNZ72657.1 - 2.3e-58 196.0 0.7 2.5e-33 115.0 0.0 5.1 3 2 2 5 5 5 3 Protein of unknown function (DUF2408) MscS_porin PF12795.2 KNZ72657.1 - 0.00062 19.1 3.3 0.36 10.1 0.3 2.6 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain MitMem_reg PF13012.1 KNZ72657.1 - 0.019 15.0 1.2 0.3 11.1 0.1 3.0 1 1 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF2968 PF11180.3 KNZ72657.1 - 0.085 12.2 2.9 0.097 12.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) FUSC PF04632.7 KNZ72657.1 - 0.096 11.1 0.1 0.12 10.7 0.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Snapin_Pallidin PF14712.1 KNZ72657.1 - 0.096 13.0 16.4 0.19 12.0 0.5 5.3 6 0 0 6 6 6 0 Snapin/Pallidin Spc7 PF08317.6 KNZ72657.1 - 0.14 10.8 6.6 0.054 12.1 0.2 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein Laminin_II PF06009.7 KNZ72657.1 - 1.1 9.0 6.2 11 5.7 0.2 3.7 4 0 0 4 4 4 0 Laminin Domain II Reo_sigmaC PF04582.7 KNZ72657.1 - 2.3 7.3 6.4 15 4.6 0.0 3.2 2 1 0 4 4 4 0 Reovirus sigma C capsid protein Nucleoplasmin PF03066.10 KNZ72657.1 - 7.4 6.0 15.1 15 5.0 10.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin Tropomyosin_1 PF12718.2 KNZ72658.1 - 3e-41 140.6 34.2 3.8e-41 140.2 23.7 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KNZ72658.1 - 4.2e-09 35.8 33.2 2.8e-07 29.8 23.0 2.3 1 1 0 1 1 1 1 Tropomyosin Flagellin_C PF00700.16 KNZ72658.1 - 0.034 14.3 5.7 0.18 11.9 0.5 2.5 2 1 1 3 3 2 0 Bacterial flagellin C-terminal helical region DUF1854 PF08909.6 KNZ72658.1 - 0.037 13.6 1.0 0.064 12.8 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1854) p31comet PF06581.7 KNZ72658.1 - 0.086 11.6 5.7 0.042 12.7 0.9 2.2 1 1 0 2 2 2 0 Mad1 and Cdc20-bound-Mad2 binding LXG PF04740.7 KNZ72658.1 - 0.38 10.5 17.1 0.16 11.6 9.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily AAA_13 PF13166.1 KNZ72658.1 - 0.51 8.7 18.1 0.81 8.0 12.5 1.3 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 KNZ72658.1 - 0.62 9.6 34.2 8 6.0 23.7 2.0 1 1 0 1 1 1 0 IncA protein ERM PF00769.14 KNZ72658.1 - 0.66 9.4 36.2 0.82 9.1 25.1 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ADIP PF11559.3 KNZ72658.1 - 0.85 9.5 30.9 0.54 10.1 7.2 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.3 KNZ72658.1 - 0.91 8.7 23.6 0.64 9.2 11.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Acyl-CoA_dh_2 PF08028.6 KNZ72658.1 - 1 9.6 8.5 1.6 8.9 4.3 2.1 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Spc7 PF08317.6 KNZ72658.1 - 1.4 7.5 24.6 1.7 7.2 17.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 KNZ72658.1 - 1.5 7.7 22.7 1.8 7.3 15.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FliJ PF02050.11 KNZ72658.1 - 1.5 8.8 31.2 0.45 10.5 13.1 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein CENP-F_leu_zip PF10473.4 KNZ72658.1 - 2.3 8.0 34.3 1.1e+02 2.6 3.3 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 KNZ72658.1 - 2.4 8.1 35.2 10 6.0 16.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) GAS PF13851.1 KNZ72658.1 - 4.2 6.4 30.6 12 5.0 21.2 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 KNZ72658.1 - 4.9 4.3 29.1 12 3.0 20.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Med4 PF10018.4 KNZ72658.1 - 5.1 6.4 23.0 0.43 9.9 6.7 2.5 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Cob_adeno_trans PF01923.13 KNZ72658.1 - 6.6 6.4 12.0 20 4.8 7.1 2.4 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DNA_ligase_A_C PF04679.10 KNZ72658.1 - 8.4 6.8 6.7 8.2 6.9 0.2 2.5 1 1 1 2 2 2 0 ATP dependent DNA ligase C terminal region SelR PF01641.13 KNZ72659.1 - 1.6e-54 182.8 0.1 1.8e-54 182.6 0.1 1.0 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.1 KNZ72659.1 - 0.0057 16.4 2.2 0.068 13.0 0.1 2.9 2 1 1 3 3 3 1 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.2 KNZ72659.1 - 0.1 12.4 3.3 2.2 8.1 2.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon Yippee-Mis18 PF03226.9 KNZ72659.1 - 0.11 12.5 0.4 0.72 9.9 0.3 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2296 PF10058.4 KNZ72659.1 - 0.11 12.1 0.3 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) GFA PF04828.9 KNZ72659.1 - 0.13 12.2 0.5 2.1 8.3 0.0 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme TF_Zn_Ribbon PF08271.7 KNZ72659.1 - 0.25 10.7 2.3 1.1 8.6 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 KNZ72659.1 - 0.26 10.5 2.4 7.9 5.8 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L37e PF01907.14 KNZ72659.1 - 1.7 8.4 4.9 4.7 7.0 0.6 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e IF4E PF01652.13 KNZ72660.1 - 1.4e-47 161.2 0.2 2.1e-47 160.7 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Herpes_BLLF1 PF05109.8 KNZ72660.1 - 0.063 11.2 3.6 0.081 10.8 2.5 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Kei1 PF08552.6 KNZ72661.1 - 1.1e-38 132.7 3.2 1.1e-38 132.7 2.2 1.6 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 DUF4199 PF13858.1 KNZ72661.1 - 0.063 13.1 9.3 0.11 12.3 6.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) PQ-loop PF04193.9 KNZ72662.1 - 6.8e-30 102.4 7.1 1.2e-17 63.1 1.0 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 KNZ72662.1 - 0.037 13.8 2.3 1 9.2 0.1 2.8 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange ER_lumen_recept PF00810.13 KNZ72662.1 - 0.077 13.4 0.4 0.18 12.3 0.2 1.6 1 1 0 1 1 1 0 ER lumen protein retaining receptor NfeD PF01957.13 KNZ72662.1 - 2.6 8.1 8.0 0.5 10.5 0.1 2.8 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding NSP10 PF09401.5 KNZ72663.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA synthesis protein NSP10 rve PF00665.21 KNZ72664.1 - 0.00034 20.7 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HpaB_N PF11794.3 KNZ72666.1 - 0.047 13.0 0.1 0.06 12.7 0.1 1.1 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Coatomer_WDAD PF04053.9 KNZ72668.1 - 1.4e-154 515.1 0.0 2.6e-154 514.2 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 KNZ72668.1 - 6.7e-50 165.2 7.4 4.9e-09 35.7 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KNZ72668.1 - 0.00026 20.7 0.1 3.7 7.3 0.0 4.8 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 KNZ72668.1 - 0.0029 15.8 0.2 1.2 7.1 0.0 3.3 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Sugar_tr PF00083.19 KNZ72669.1 - 6.3e-129 430.4 21.1 7.1e-129 430.2 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ72669.1 - 2.9e-24 85.4 24.9 2.9e-24 85.4 17.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 KNZ72670.1 - 3.3e-29 102.3 0.4 5.5e-29 101.6 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ72670.1 - 4.3e-18 65.4 0.1 8e-18 64.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ72670.1 - 1.8e-15 57.1 0.1 2.9e-15 56.4 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KNZ72670.1 - 7.2e-07 28.9 0.0 4.5e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KNZ72670.1 - 2.3e-06 26.9 0.8 0.00016 20.9 0.0 2.4 1 1 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 KNZ72670.1 - 8.1e-06 25.6 0.1 0.0042 16.8 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 KNZ72670.1 - 3.3e-05 23.2 0.3 0.023 13.9 0.1 3.3 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 KNZ72670.1 - 0.0089 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.11 KNZ72670.1 - 0.21 10.9 1.1 1.2 8.5 0.0 2.6 4 0 0 4 4 4 0 Phospholipase/Carboxylesterase Vfa1 PF08432.5 KNZ72671.1 - 4 7.4 11.7 15 5.5 0.3 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 NOA36 PF06524.7 KNZ72671.1 - 7.6 5.7 18.5 12 5.0 12.8 1.2 1 0 0 1 1 1 0 NOA36 protein Hist_deacetyl PF00850.14 KNZ72672.1 - 1.1e-77 261.4 0.1 2.2e-77 260.3 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain Peptidase_M24 PF00557.19 KNZ72674.1 - 2.2e-40 138.4 0.0 4.2e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Nup188 PF10487.4 KNZ72674.1 - 1.3e-17 63.0 0.0 3.1e-14 51.9 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 adh_short PF00106.20 KNZ72675.1 - 2.2e-09 37.4 0.0 3.9e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ72675.1 - 6.9e-07 29.1 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KNZ72675.1 - 0.00027 20.7 0.1 0.0007 19.4 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase BTB PF00651.26 KNZ72675.1 - 0.0017 18.2 1.4 0.0034 17.3 0.4 1.8 2 0 0 2 2 2 1 BTB/POZ domain Ham1p_like PF01725.11 KNZ72676.1 - 9.4e-36 122.9 0.0 1e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Gag_spuma PF03276.9 KNZ72678.1 - 0.025 12.9 0.2 0.029 12.7 0.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF1768 PF08719.6 KNZ72679.1 - 1.3e-22 80.2 0.0 1.8e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) TAFII28 PF04719.9 KNZ72680.1 - 3.8e-28 97.1 0.0 5.4e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.18 KNZ72680.1 - 0.0026 17.7 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BRCT PF00533.21 KNZ72681.1 - 1.1e-06 28.6 0.0 2.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KNZ72681.1 - 6.1e-05 22.7 0.0 0.00031 20.5 0.0 2.1 1 1 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 KNZ72681.1 - 9.4e-05 22.4 0.1 0.00031 20.8 0.1 1.9 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 KNZ72681.1 - 0.0049 16.5 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) Mitofilin PF09731.4 KNZ72681.1 - 1.2 7.7 3.6 1.7 7.2 2.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein eIF2A PF08662.6 KNZ72682.1 - 2.9e-41 141.3 0.4 6.7e-36 123.8 0.0 4.6 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KNZ72682.1 - 6.3e-07 29.0 0.6 0.4 10.6 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat RRM_6 PF14259.1 KNZ72682.1 - 1.1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KNZ72682.1 - 1.2e-06 27.9 0.0 2.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ72682.1 - 0.024 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) P4Ha_N PF08336.6 KNZ72682.1 - 0.83 9.4 4.1 1.6 8.5 2.9 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Pkinase PF00069.20 KNZ72683.1 - 2.4e-61 207.1 0.0 3e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72683.1 - 2.5e-30 105.4 0.0 4.4e-30 104.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ72683.1 - 0.00057 18.9 0.0 0.00086 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ72683.1 - 0.035 13.8 0.2 0.5 10.0 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Clathrin PF00637.15 KNZ72685.1 - 2.8e-25 88.5 0.4 8.9e-25 86.9 0.1 1.9 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 KNZ72685.1 - 0.0059 16.4 9.9 0.012 15.4 5.3 2.3 1 1 1 2 2 2 1 Ring finger domain Vps39_1 PF10366.4 KNZ72685.1 - 0.0081 16.1 0.6 0.057 13.4 0.1 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KNZ72685.1 - 0.011 15.9 0.1 0.026 14.7 0.1 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-Apc11 PF12861.2 KNZ72685.1 - 0.25 11.2 2.0 0.35 10.7 0.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4628 PF15429.1 KNZ72685.1 - 0.34 10.2 1.9 0.57 9.5 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) zf-C3HC4_3 PF13920.1 KNZ72685.1 - 0.48 10.1 5.7 0.94 9.2 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ72685.1 - 0.77 9.5 5.4 1.4 8.7 2.8 2.1 1 1 0 1 1 1 0 zinc-RING finger domain RRN3 PF05327.6 KNZ72685.1 - 1.6 6.7 6.1 2.7 5.9 4.2 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TAF4 PF05236.9 KNZ72686.1 - 1.5e-27 96.5 15.1 7.8e-27 94.2 10.5 2.0 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Sporozoite_P67 PF05642.6 KNZ72686.1 - 0.47 8.2 10.3 0.72 7.6 7.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_L13 PF00572.13 KNZ72687.1 - 2.5e-47 160.1 0.3 3.2e-47 159.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 UAF_Rrn10 PF05234.6 KNZ72688.1 - 0.032 14.2 0.0 6.8 6.7 0.0 2.3 2 0 0 2 2 2 0 UAF complex subunit Rrn10 AAA_21 PF13304.1 KNZ72688.1 - 0.2 11.6 2.1 0.18 11.7 1.0 1.4 1 1 0 1 1 1 0 AAA domain TPR_11 PF13414.1 KNZ72689.1 - 5.5e-17 61.1 1.7 2.8e-06 26.8 0.0 5.4 3 1 3 6 6 6 3 TPR repeat TPR_2 PF07719.12 KNZ72689.1 - 6.2e-13 47.5 4.6 0.00051 19.7 0.0 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ72689.1 - 8.9e-11 40.9 1.1 0.016 14.7 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ72689.1 - 7.3e-10 38.6 4.5 0.0028 17.5 0.1 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ72689.1 - 2.2e-08 33.6 0.0 0.0025 17.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ72689.1 - 2.6e-08 33.7 11.4 0.086 13.5 0.0 7.3 6 2 2 8 8 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ72689.1 - 2.7e-07 31.0 0.1 2.6e-05 24.7 0.0 5.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ72689.1 - 1.4e-06 27.6 5.2 1.2 9.0 0.0 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ72689.1 - 2e-05 24.8 0.3 0.05 13.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ72689.1 - 6.7e-05 22.3 0.1 0.3 10.9 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ72689.1 - 0.00053 19.7 8.3 0.38 10.6 0.1 6.0 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ72689.1 - 0.027 14.8 3.3 51 4.6 0.0 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat Apc3 PF12895.2 KNZ72689.1 - 0.035 14.2 0.0 0.26 11.4 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 KNZ72689.1 - 0.068 12.5 1.0 0.46 9.8 0.1 2.9 4 1 0 4 4 4 0 26S proteasome subunit RPN7 TPR_10 PF13374.1 KNZ72689.1 - 0.1 12.5 11.4 1.2 9.1 0.2 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.15 KNZ72690.1 - 0.2 10.6 0.1 0.28 10.1 0.1 1.1 1 0 0 1 1 1 0 E1-E2 ATPase Rab5ip PF07019.7 KNZ72691.1 - 1e-15 57.6 2.3 1.3e-15 57.2 1.6 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) MARVEL PF01284.18 KNZ72691.1 - 0.14 11.9 4.2 0.83 9.4 0.2 2.1 1 1 1 2 2 2 0 Membrane-associating domain Semialdhyde_dhC PF02774.13 KNZ72692.1 - 5.1e-35 120.9 0.0 7.5e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KNZ72692.1 - 1.6e-29 102.6 0.0 4.4e-29 101.2 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KNZ72692.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RNase_PH PF01138.16 KNZ72693.1 - 1.4e-28 99.8 0.1 3.3e-28 98.6 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 PNPase PF03726.9 KNZ72693.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain SMC_N PF02463.14 KNZ72694.1 - 1.3e-19 70.3 0.0 2.5e-19 69.4 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KNZ72694.1 - 6e-07 29.9 36.2 6e-07 29.9 25.1 5.6 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KNZ72694.1 - 0.0084 16.1 5.0 0.019 14.9 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KNZ72694.1 - 0.024 14.1 0.0 0.097 12.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KNZ72694.1 - 0.46 9.6 3.6 0.89 8.6 0.2 2.8 2 1 0 3 3 3 0 Reovirus sigma C capsid protein 4HBT PF03061.17 KNZ72696.1 - 8.5e-06 25.8 0.5 1.5e-05 25.0 0.1 1.6 2 0 0 2 2 2 1 Thioesterase superfamily 2OG-FeII_Oxy_2 PF13532.1 KNZ72697.1 - 4.5e-14 52.7 0.0 6.2e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KNZ72697.1 - 8.1e-06 26.0 0.0 2e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RVP_2 PF08284.6 KNZ72698.1 - 0.00083 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KNZ72698.1 - 0.0032 17.9 0.0 0.0068 16.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease MSP1b PF03429.8 KNZ72698.1 - 0.12 10.2 0.0 0.41 8.4 0.0 1.7 2 0 0 2 2 2 0 Major surface protein 1B Asp_protease PF09668.5 KNZ72698.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease DUF553 PF04473.7 KNZ72701.1 - 0.0071 15.6 0.1 0.013 14.7 0.1 1.6 1 1 0 1 1 1 1 Transglutaminase-like domain eIF3g PF12353.3 KNZ72701.1 - 0.021 14.7 1.3 0.041 13.8 0.2 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G UBA_e1_C PF09358.5 KNZ72701.1 - 0.074 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain SAP18 PF06487.7 KNZ72703.1 - 4.6e-27 94.2 0.0 5.6e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Glyco_transf_52 PF07922.6 KNZ72703.1 - 0.042 12.8 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 52 RRM_3 PF08777.6 KNZ72704.1 - 3.1e-05 23.7 0.0 0.00019 21.2 0.0 2.0 1 1 0 1 1 1 1 RNA binding motif RRM_6 PF14259.1 KNZ72704.1 - 0.00049 20.0 0.0 0.05 13.5 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KNZ72704.1 - 0.0031 17.1 0.0 0.096 12.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PSP PF04046.11 KNZ72706.1 - 0.025 13.9 0.0 0.074 12.4 0.0 1.8 1 0 0 1 1 1 0 PSP EF_assoc_2 PF08356.7 KNZ72706.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 EF hand associated Ribosomal_L4 PF00573.17 KNZ72707.1 - 0.0043 16.4 5.3 0.091 12.1 0.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L4/L1 family Peptidase_MA_2 PF13485.1 KNZ72708.1 - 0.11 12.5 0.1 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase MA superfamily DUF1768 PF08719.6 KNZ72710.1 - 7.7e-17 61.4 0.0 8.6e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) ATG22 PF11700.3 KNZ72712.1 - 2.6e-98 329.5 22.6 5.3e-97 325.2 15.7 2.0 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like Amidase PF01425.16 KNZ72713.1 - 4.5e-40 137.8 0.1 4.9e-39 134.4 0.1 2.1 1 1 0 1 1 1 1 Amidase Neur_chan_memb PF02932.11 KNZ72716.1 - 3.6 7.3 5.4 6.5 6.5 3.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region p450 PF00067.17 KNZ72717.1 - 0.00056 18.5 0.0 0.00099 17.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 AATF-Che1 PF13339.1 KNZ72717.1 - 0.014 15.5 1.9 0.035 14.2 0.1 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor GST_N_3 PF13417.1 KNZ72718.1 - 1.2e-21 76.6 0.0 2.6e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KNZ72718.1 - 1.7e-12 47.1 0.0 3.6e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KNZ72718.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF605 PF04652.11 KNZ72721.1 - 0.0069 15.8 12.3 0.0072 15.7 8.5 1.1 1 0 0 1 1 1 1 Vta1 like Transposase_mut PF00872.13 KNZ72721.1 - 0.1 11.1 0.2 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 Transposase, Mutator family LAP1C PF05609.7 KNZ72721.1 - 2.3 6.8 12.9 0.97 8.0 7.3 1.5 1 1 1 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) TPR_10 PF13374.1 KNZ72722.1 - 5.8e-53 175.4 7.5 1.8e-09 37.1 0.0 6.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ72722.1 - 5.3e-40 135.2 15.1 2.6e-14 52.9 0.8 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ72722.1 - 8.5e-15 54.9 7.4 3.1e-05 24.4 0.1 4.4 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ72722.1 - 2e-13 49.7 8.6 0.0027 17.3 0.1 5.0 2 2 2 4 4 4 4 TPR repeat TPR_4 PF07721.9 KNZ72722.1 - 1.3e-12 46.8 4.4 0.22 12.0 0.1 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ72722.1 - 3e-10 39.4 4.9 0.044 13.9 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat NB-ARC PF00931.17 KNZ72722.1 - 7.4e-10 38.1 1.3 5.6e-09 35.2 0.6 2.4 1 1 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.23 KNZ72722.1 - 2.7e-09 36.2 13.2 0.66 9.6 0.1 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ72722.1 - 3.2e-09 36.0 14.1 1 9.4 0.1 7.1 6 0 0 6 6 6 3 Tetratricopeptide repeat Patatin PF01734.17 KNZ72722.1 - 6.2e-09 36.0 0.0 1.6e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_7 PF13176.1 KNZ72722.1 - 1e-08 34.3 16.4 0.018 14.7 0.1 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ72722.1 - 7.3e-05 23.0 17.8 0.99 9.7 0.1 5.3 1 1 5 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ72722.1 - 0.00011 22.5 16.0 5.6 7.8 0.0 6.7 4 2 2 6 6 6 1 Tetratricopeptide repeat DUF4404 PF14357.1 KNZ72722.1 - 0.00044 20.6 4.1 1.4 9.3 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4404) C_GCAxxG_C_C PF09719.5 KNZ72722.1 - 0.0068 16.2 0.4 73 3.1 0.0 4.4 4 0 0 4 4 4 0 Putative redox-active protein (C_GCAxxG_C_C) SSI PF00720.12 KNZ72722.1 - 0.011 15.5 2.4 9.2 6.2 0.1 3.3 2 1 0 3 3 3 0 Subtilisin inhibitor-like AAA PF00004.24 KNZ72722.1 - 0.056 13.6 0.0 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) YbaB_DNA_bd PF02575.11 KNZ72722.1 - 0.12 12.2 11.5 17 5.3 0.1 4.5 2 1 2 4 4 4 0 YbaB/EbfC DNA-binding family Caps_synth_GfcC PF06251.6 KNZ72722.1 - 5.2 6.1 13.1 23 4.0 5.7 3.1 1 1 2 3 3 3 0 Capsule biosynthesis GfcC Glyoxalase_4 PF13669.1 KNZ72724.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.7 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily rRNA_proc-arch PF13234.1 KNZ72728.1 - 0.092 11.8 0.8 0.13 11.3 0.3 1.4 1 1 1 2 2 2 0 rRNA-processing arch domain RVP_2 PF08284.6 KNZ72729.1 - 0.066 13.1 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease p450 PF00067.17 KNZ72731.1 - 8.4e-55 186.1 0.1 2e-37 128.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 TIP120 PF08623.5 KNZ72732.1 - 2.1e-50 170.6 2.1 3.7e-50 169.8 0.1 2.5 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 KNZ72732.1 - 2.4e-19 69.4 14.7 0.00034 20.8 0.3 8.7 6 2 3 9 9 9 6 HEAT repeats HEAT PF02985.17 KNZ72732.1 - 1.4e-14 52.7 25.0 0.016 15.2 0.0 12.2 13 0 0 13 13 12 4 HEAT repeat HEAT_EZ PF13513.1 KNZ72732.1 - 2.4e-10 40.5 32.4 0.0079 16.6 0.2 11.8 11 1 2 13 13 12 3 HEAT-like repeat Cnd1 PF12717.2 KNZ72732.1 - 2.2e-09 37.4 0.9 0.018 14.8 0.1 5.6 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KNZ72732.1 - 7.4e-07 28.7 4.4 0.039 13.2 0.2 4.8 4 1 1 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 KNZ72732.1 - 1.5e-06 28.4 0.2 16 5.9 0.0 7.3 7 1 1 8 8 8 0 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 KNZ72732.1 - 0.0017 18.2 5.2 7.9 6.5 0.0 6.7 6 2 2 8 8 8 1 Rix1 complex component involved in 60S ribosome maturation DUF3385 PF11865.3 KNZ72732.1 - 0.0018 18.2 2.5 0.011 15.6 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) ParcG PF10274.4 KNZ72732.1 - 0.037 13.9 4.6 4.9 7.0 0.0 4.8 6 0 0 6 6 6 0 Parkin co-regulated protein MMS19_C PF12460.3 KNZ72732.1 - 0.084 11.5 27.8 0.013 14.2 0.6 5.6 6 3 1 7 7 7 0 RNAPII transcription regulator C-terminal Nop14 PF04147.7 KNZ72732.1 - 0.2 9.5 2.7 0.52 8.1 1.8 1.6 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KNZ72732.1 - 2.6 7.5 6.9 5.5 6.4 4.8 1.5 1 0 0 1 1 1 0 Nucleoplasmin Pkinase PF00069.20 KNZ72734.1 - 2.3e-64 217.0 0.0 2.9e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72734.1 - 1.5e-23 83.1 0.0 2.1e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ72734.1 - 1.2e-05 24.4 0.0 2.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like AAA PF00004.24 KNZ72736.1 - 4.1e-42 143.5 0.0 6.6e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KNZ72736.1 - 1.6e-24 85.5 0.1 4.8e-24 84.0 0.1 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KNZ72736.1 - 1.6e-19 69.5 3.0 1.6e-19 69.5 2.1 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 KNZ72736.1 - 4.9e-07 29.9 1.0 0.0077 16.3 0.0 3.2 3 1 1 4 4 3 2 AAA domain RuvB_N PF05496.7 KNZ72736.1 - 5.6e-06 25.5 0.0 9.9e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KNZ72736.1 - 6.8e-06 25.8 0.0 6.4e-05 22.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KNZ72736.1 - 9.3e-06 25.5 0.0 3.3e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KNZ72736.1 - 1.3e-05 25.2 0.2 0.0015 18.5 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 KNZ72736.1 - 1.5e-05 25.7 0.4 6.4e-05 23.7 0.0 2.3 3 1 0 3 3 1 1 AAA domain IstB_IS21 PF01695.12 KNZ72736.1 - 1.6e-05 24.3 0.0 3.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KNZ72736.1 - 0.00016 21.1 0.2 0.19 11.1 0.1 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 KNZ72736.1 - 0.00026 20.0 0.0 0.0013 17.7 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KNZ72736.1 - 0.00035 20.4 0.1 0.0011 18.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 KNZ72736.1 - 0.00074 18.3 0.0 0.0019 16.9 0.0 1.5 1 1 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 KNZ72736.1 - 0.002 18.0 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 KNZ72736.1 - 0.0028 17.2 0.1 0.0071 15.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain KaiC PF06745.8 KNZ72736.1 - 0.0031 16.6 0.1 0.85 8.6 0.0 2.3 1 1 1 2 2 2 1 KaiC AAA_18 PF13238.1 KNZ72736.1 - 0.0036 17.6 0.1 0.013 15.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 KNZ72736.1 - 0.0048 17.0 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 KNZ72736.1 - 0.01 15.5 0.1 0.3 10.7 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 KNZ72736.1 - 0.014 14.4 0.1 0.29 10.1 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_19 PF13245.1 KNZ72736.1 - 0.022 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 KNZ72736.1 - 0.024 14.3 0.0 0.24 11.0 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 KNZ72736.1 - 0.03 13.4 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 KNZ72736.1 - 0.03 14.3 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.10 KNZ72736.1 - 0.031 14.0 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 KNZ72736.1 - 0.033 13.4 0.4 0.067 12.4 0.1 1.7 2 1 0 2 2 1 0 PhoH-like protein Parvo_NS1 PF01057.12 KNZ72736.1 - 0.052 12.4 0.0 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 KNZ72736.1 - 0.089 12.2 0.0 0.53 9.7 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Guanylate_kin PF00625.16 KNZ72736.1 - 0.12 11.7 0.0 0.33 10.3 0.0 1.6 2 0 0 2 2 1 0 Guanylate kinase AAA_28 PF13521.1 KNZ72736.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 KNZ72736.1 - 0.15 11.9 0.0 0.42 10.4 0.0 1.7 2 0 0 2 2 1 0 Torsin Viral_helicase1 PF01443.13 KNZ72736.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.1 KNZ72736.1 - 0.32 10.9 2.8 3.6 7.4 0.0 2.5 2 1 0 3 3 2 0 AAA domain APH PF01636.18 KNZ72737.1 - 1.6e-07 31.3 0.0 2.8e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ72737.1 - 0.0054 16.3 0.0 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KNZ72737.1 - 0.12 11.3 0.2 0.37 9.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L19e PF01280.15 KNZ72738.1 - 1.1e-60 203.6 12.7 1.1e-60 203.6 8.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.20 KNZ72738.1 - 0.0084 15.5 0.0 0.025 14.0 0.0 1.8 1 0 0 1 1 1 1 S4 domain MOZ_SAS PF01853.13 KNZ72739.1 - 1.1e-63 213.8 0.1 1.8e-63 213.1 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KNZ72739.1 - 1.1e-07 31.4 0.2 2.7e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 KNZ72739.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AA_permease_2 PF13520.1 KNZ72740.1 - 3.6e-43 147.6 42.3 4.5e-43 147.3 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KNZ72740.1 - 7.4e-11 41.0 39.2 1.3e-10 40.2 27.1 1.3 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 KNZ72741.1 - 7.8e-35 120.2 0.0 1.2e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72741.1 - 4.2e-12 45.6 0.0 6.5e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ72741.1 - 0.002 17.1 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ72741.1 - 0.021 14.5 0.1 0.11 12.1 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family tRNA-synt_His PF13393.1 KNZ72744.1 - 0.03 13.4 1.0 0.041 12.9 0.7 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase zf-CCHC PF00098.18 KNZ72745.1 - 0.0012 18.6 12.8 0.02 14.8 0.5 3.9 5 1 0 5 5 5 2 Zinc knuckle RNase_H PF00075.19 KNZ72746.1 - 5.4e-05 23.5 0.0 8.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 RNase H p450 PF00067.17 KNZ72750.1 - 1.7e-65 221.3 0.0 1.2e-64 218.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KNZ72751.1 - 1.2e-63 215.2 0.0 4.8e-38 130.8 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 PH PF00169.24 KNZ72752.1 - 1e-05 25.6 0.0 2.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 PH domain MCPVI PF02993.9 KNZ72753.1 - 0.17 12.0 1.5 0.24 11.5 1.0 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Ded_cyto PF06920.8 KNZ72753.1 - 0.17 11.1 2.3 0.29 10.4 1.6 1.3 1 0 0 1 1 1 0 Dedicator of cytokinesis Fib_alpha PF08702.5 KNZ72753.1 - 6.4 6.8 9.1 8.6 6.4 1.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Glyco_transf_17 PF04724.8 KNZ72754.1 - 5e-100 334.9 0.4 5.9e-100 334.7 0.3 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 Glyco_hydro_18 PF00704.23 KNZ72755.1 - 1e-55 189.5 0.9 1.5e-55 188.9 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 zf-C2H2 PF00096.21 KNZ72756.1 - 2.7e-12 46.2 14.8 0.00021 21.4 1.1 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ72756.1 - 2.9e-09 36.6 14.8 0.0005 20.2 0.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KNZ72756.1 - 6.5e-07 29.3 10.4 0.0001 22.4 0.3 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 KNZ72756.1 - 0.007 16.5 6.6 4.8 7.5 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KNZ72756.1 - 0.042 14.0 4.2 0.64 10.2 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KNZ72756.1 - 0.47 10.7 2.8 0.46 10.8 0.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 KNZ72756.1 - 1 9.3 8.5 0.68 9.9 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Mito_carr PF00153.22 KNZ72757.1 - 4e-65 215.5 4.1 8.8e-23 79.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3844 PF12955.2 KNZ72758.1 - 2.3e-30 104.7 3.8 3.7e-30 104.0 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 KNZ72758.1 - 5.7 7.1 9.8 12 6.1 6.8 1.5 1 0 0 1 1 1 0 EGF-like domain Gti1_Pac2 PF09729.4 KNZ72759.1 - 7.5e-26 90.9 0.6 9e-23 80.9 0.4 2.3 1 1 0 1 1 1 1 Gti1/Pac2 family Glutaredoxin PF00462.19 KNZ72760.1 - 0.023 14.7 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin O-FucT PF10250.4 KNZ72761.1 - 2.9e-08 33.2 0.0 0.00011 21.4 0.0 2.1 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Esterase_phd PF10503.4 KNZ72762.1 - 5.2e-25 87.9 1.1 7.5e-25 87.4 0.8 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 KNZ72762.1 - 1.6e-12 46.8 13.9 1.6e-12 46.8 9.7 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 KNZ72762.1 - 3.4e-09 36.2 1.4 5.6e-09 35.5 1.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KNZ72762.1 - 4.8e-07 29.6 0.2 6.8e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ72762.1 - 2.6e-05 24.2 0.2 3.6e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KNZ72762.1 - 0.058 12.8 1.2 0.15 11.4 0.9 1.8 1 1 0 1 1 1 0 Putative esterase Glutaredoxin PF00462.19 KNZ72763.1 - 3.7e-12 46.0 0.0 6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 KNZ72763.1 - 0.016 15.3 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain GST_N_3 PF13417.1 KNZ72763.1 - 0.025 14.7 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF2847 PF11009.3 KNZ72763.1 - 0.031 13.8 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) HAD_2 PF13419.1 KNZ72764.1 - 4.8e-18 65.9 0.0 6.6e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KNZ72764.1 - 1.7e-08 35.1 0.0 4.2e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KNZ72764.1 - 0.033 14.0 0.0 6.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KNZ72764.1 - 0.083 12.6 0.0 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 HAD-hyrolase-like DUF2681 PF10883.3 KNZ72765.1 - 0.27 11.4 1.0 0.41 10.8 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Bax1-I PF01027.15 KNZ72766.1 - 5.9e-46 156.6 24.1 7e-46 156.4 16.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 VanW PF04294.8 KNZ72766.1 - 0.16 11.1 0.0 0.4 9.8 0.0 1.6 2 0 0 2 2 2 0 VanW like protein CMAS PF02353.15 KNZ72767.1 - 4.7e-32 111.1 0.1 6.4e-32 110.7 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 KNZ72767.1 - 3.3e-12 46.2 0.0 5e-12 45.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ72767.1 - 6.3e-12 45.8 0.0 1.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ72767.1 - 3.5e-11 43.6 0.0 6.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ72767.1 - 6e-10 39.4 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ72767.1 - 4.1e-09 36.3 0.0 6.3e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ72767.1 - 7.3e-07 28.7 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KNZ72767.1 - 1.5e-06 28.5 0.0 2.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KNZ72767.1 - 4.3e-05 22.6 0.0 8.3e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase tRNA_U5-meth_tr PF05958.6 KNZ72767.1 - 0.00019 20.2 0.0 0.00027 19.7 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TehB PF03848.9 KNZ72767.1 - 0.001 18.2 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 KNZ72767.1 - 0.004 16.6 0.0 0.0055 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 KNZ72767.1 - 0.0083 15.5 0.0 0.028 13.8 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW GidB PF02527.10 KNZ72767.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DOT1 PF08123.8 KNZ72767.1 - 0.019 14.2 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.15 KNZ72767.1 - 0.034 13.1 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KNZ72767.1 - 0.049 13.6 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KNZ72767.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 KNZ72767.1 - 0.085 12.3 0.1 0.17 11.3 0.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF938) IBD PF10416.4 KNZ72767.1 - 0.099 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD MDM31_MDM32 PF08118.6 KNZ72768.1 - 6.9e-146 486.6 0.2 8.4e-146 486.3 0.1 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins HPP PF04982.8 KNZ72770.1 - 1.4 8.7 4.4 2.7 7.8 3.0 1.4 1 0 0 1 1 1 0 HPP family BAR PF03114.13 KNZ72771.1 - 9.3e-44 149.6 0.1 1.2e-43 149.3 0.1 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 KNZ72771.1 - 0.0048 16.2 0.4 0.017 14.4 0.1 1.8 2 0 0 2 2 2 1 Arfaptin-like domain SYF2 PF08231.7 KNZ72771.1 - 0.057 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 SYF2 splicing factor UvdE PF03851.9 KNZ72772.1 - 8.7e-84 280.7 0.0 1.2e-83 280.3 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE RabGAP-TBC PF00566.13 KNZ72774.1 - 8e-52 175.8 0.3 1.6e-51 174.8 0.2 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Scaffolding_pro PF11418.3 KNZ72774.1 - 0.68 10.2 6.1 18 5.7 0.0 3.8 4 0 0 4 4 4 0 Phi29 scaffolding protein DivIC PF04977.10 KNZ72774.1 - 1.6 8.3 8.1 4 6.9 0.1 3.1 2 1 1 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.3 KNZ72774.1 - 2.3 8.0 11.8 0.12 12.1 3.0 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 KNZ72774.1 - 3.3 7.2 12.8 0.29 10.7 5.3 1.8 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 KNZ72774.1 - 3.4 6.6 10.8 0.51 9.3 4.3 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 Yippee-Mis18 PF03226.9 KNZ72775.1 - 2e-07 30.9 0.1 2.4e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Amidohydro_4 PF13147.1 KNZ72776.1 - 3.3e-25 89.6 0.2 1.2e-13 51.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KNZ72776.1 - 2e-23 83.5 0.0 2.9e-11 43.6 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KNZ72776.1 - 2e-12 46.7 0.1 4.5e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KNZ72776.1 - 1.9e-06 27.3 0.0 0.056 12.6 0.0 2.5 2 1 1 3 3 3 2 Amidohydrolase family zf-RING_2 PF13639.1 KNZ72777.1 - 3.9e-13 48.9 6.0 4.3e-13 48.8 3.4 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KNZ72777.1 - 8.2e-07 29.0 0.8 2e-06 27.8 0.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KNZ72777.1 - 1.3e-05 24.7 1.8 2.7e-05 23.7 1.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KNZ72777.1 - 1.4e-05 24.9 4.2 3.1e-05 23.8 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KNZ72777.1 - 2.5e-05 24.0 0.6 5.7e-05 22.8 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KNZ72777.1 - 2.6e-05 23.7 2.2 5.4e-05 22.6 1.5 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 KNZ72777.1 - 3.9e-05 23.2 2.7 7.9e-05 22.2 1.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNZ72777.1 - 0.00028 20.4 0.7 0.00059 19.4 0.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KNZ72777.1 - 0.012 15.5 1.6 0.035 14.0 1.2 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KNZ72777.1 - 0.017 15.1 2.5 0.034 14.1 1.7 1.5 1 0 0 1 1 1 0 RING-variant domain Josephin PF02099.12 KNZ72778.1 - 1.4e-45 154.7 0.1 1.4e-45 154.7 0.1 1.8 2 0 0 2 2 2 1 Josephin UIM PF02809.15 KNZ72778.1 - 0.035 13.6 14.1 0.68 9.6 0.3 4.0 3 0 0 3 3 3 0 Ubiquitin interaction motif HlyD PF00529.15 KNZ72778.1 - 0.33 10.2 9.4 0.54 9.5 6.5 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Bac_rhamnosid PF05592.6 KNZ72779.1 - 2e-23 82.4 0.1 2.7e-21 75.3 0.1 2.7 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KNZ72779.1 - 2.1e-05 23.4 0.4 3.1e-05 22.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 KNZ72779.1 - 0.0068 15.0 0.1 0.0099 14.5 0.1 1.1 1 0 0 1 1 1 1 Trehalase Autoind_bind PF03472.10 KNZ72779.1 - 0.07 12.4 0.4 0.15 11.3 0.3 1.5 1 0 0 1 1 1 0 Autoinducer binding domain ATG27 PF09451.5 KNZ72780.1 - 7.1e-42 143.4 0.0 8.7e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 KNZ72780.1 - 0.00017 20.6 0.0 0.00027 20.0 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Cauli_VI PF01693.11 KNZ72781.1 - 1e-14 54.2 0.0 1.9e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin DASH_Duo1 PF08651.5 KNZ72782.1 - 1.6e-13 49.9 0.5 2.9e-13 49.1 0.4 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF572 PF04502.8 KNZ72782.1 - 0.016 14.4 10.9 0.021 14.0 7.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Atrophin-1 PF03154.10 KNZ72782.1 - 5.3 5.0 13.5 8.6 4.3 9.3 1.3 1 0 0 1 1 1 0 Atrophin-1 family DEAD PF00270.24 KNZ72783.1 - 1e-39 135.7 0.0 2.2e-39 134.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ72783.1 - 1.8e-21 75.7 0.2 7.5e-21 73.7 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 KNZ72783.1 - 8.3e-20 70.3 2.1 8.3e-20 70.3 1.5 2.4 3 0 0 3 3 3 1 DBP10CT (NUC160) domain EMP70 PF02990.11 KNZ72784.1 - 1.8e-185 617.3 1.1 2.3e-185 617.0 0.8 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 TGT PF01702.13 KNZ72785.1 - 1.5e-75 253.5 0.0 3e-75 252.5 0.0 1.5 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase tRNA-synt_1b PF00579.20 KNZ72786.1 - 9.6e-68 228.4 0.0 1.2e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 KNZ72786.1 - 0.0044 16.4 0.0 0.0085 15.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain Abhydrolase_1 PF00561.15 KNZ72787.1 - 6.1e-12 45.5 0.0 1.2e-11 44.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KNZ72787.1 - 6.5e-09 36.0 0.0 1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ribosom_S12_S23 PF00164.20 KNZ72788.1 - 9.6e-38 128.3 0.7 1.3e-37 127.9 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Transglut_core PF01841.14 KNZ72789.1 - 1.9e-10 40.9 0.0 2.9e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily CTP_transf_1 PF01148.15 KNZ72790.1 - 5.4e-74 249.1 25.0 7e-74 248.7 17.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Topoisom_I_N PF02919.10 KNZ72791.1 - 2.5e-96 321.1 0.6 2.5e-96 321.1 0.4 3.2 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KNZ72791.1 - 1.2e-86 289.6 7.7 2.7e-86 288.5 5.3 1.6 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KNZ72791.1 - 2.4e-31 107.1 0.1 2.4e-31 107.1 0.1 2.1 2 0 0 2 2 2 1 C-terminal topoisomerase domain NDUF_B12 PF08122.7 KNZ72792.1 - 2.6e-19 68.7 0.4 2.9e-19 68.5 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family MipZ PF09140.6 KNZ72792.1 - 0.017 14.2 0.0 0.017 14.1 0.0 1.0 1 0 0 1 1 1 0 ATPase MipZ Cation_ATPase_C PF00689.16 KNZ72792.1 - 0.019 14.4 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus HAD_2 PF13419.1 KNZ72793.1 - 1.1e-25 90.8 0.0 1.8e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.3 KNZ72793.1 - 0.015 14.3 0.0 0.074 12.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2608) Hydrolase_like PF13242.1 KNZ72793.1 - 0.022 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like PALP PF00291.20 KNZ72794.1 - 6.1e-75 252.2 0.1 7.9e-75 251.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KNZ72794.1 - 1.3e-40 136.8 0.0 6e-23 80.2 0.0 2.5 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Propep_M14 PF02244.11 KNZ72794.1 - 0.035 13.7 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 Carboxypeptidase activation peptide Mg_trans_NIPA PF05653.9 KNZ72794.1 - 0.21 10.5 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium transporter NIPA PHD PF00628.24 KNZ72795.1 - 6.6e-11 41.7 8.2 1.1e-10 41.0 5.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KNZ72795.1 - 0.23 10.8 4.6 0.41 9.9 3.2 1.3 1 0 0 1 1 1 0 PHD-finger Vps8 PF12816.2 KNZ72796.1 - 1.8e-67 226.3 0.0 1.4e-64 216.9 0.0 2.4 2 0 0 2 2 2 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 KNZ72796.1 - 0.00098 18.7 0.0 0.012 15.2 0.0 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS PQQ_3 PF13570.1 KNZ72796.1 - 0.059 13.6 0.2 5.6 7.3 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain WD40 PF00400.27 KNZ72796.1 - 0.71 9.8 0.0 0.71 9.8 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat COG2 PF06148.6 KNZ72797.1 - 1.7e-28 99.1 5.2 6.2e-28 97.3 3.6 2.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 KNZ72797.1 - 9.4e-22 77.4 0.0 2.5e-21 76.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) Vps51 PF08700.6 KNZ72797.1 - 0.013 15.2 2.8 0.022 14.5 0.7 2.4 2 1 0 2 2 2 0 Vps51/Vps67 IncA PF04156.9 KNZ72797.1 - 0.062 12.8 10.1 0.16 11.5 7.0 1.7 1 0 0 1 1 1 0 IncA protein MscS_porin PF12795.2 KNZ72797.1 - 0.077 12.2 8.3 0.45 9.8 5.7 2.1 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Feld-I_B PF09252.5 KNZ72797.1 - 0.1 12.5 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 Allergen Fel d I-B chain DUF972 PF06156.8 KNZ72797.1 - 1.8 8.9 4.3 3.3 8.1 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Spc7 PF08317.6 KNZ72797.1 - 1.8 7.1 10.0 0.29 9.7 4.1 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1168 PF06658.7 KNZ72798.1 - 2.4e-39 134.1 13.5 3.1e-39 133.7 9.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Cmyb_C PF09316.5 KNZ72798.1 - 0.19 11.3 0.2 0.19 11.3 0.1 2.2 2 0 0 2 2 2 0 C-myb, C-terminal RNase_H2-Ydr279 PF09468.5 KNZ72798.1 - 2.4 7.2 6.6 2.8 7.0 4.6 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CENP-N PF05238.8 KNZ72798.1 - 2.8 6.9 7.0 3.3 6.6 4.9 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like U79_P34 PF03064.11 KNZ72798.1 - 4.1 6.8 12.5 6.8 6.1 8.6 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 MCM PF00493.18 KNZ72799.1 - 3.5e-133 443.4 0.0 4.7e-133 443.0 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KNZ72799.1 - 6.9e-22 78.1 0.0 3.5e-21 75.9 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 KNZ72799.1 - 1.8e-08 34.1 0.0 4.8e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KNZ72799.1 - 1.2e-07 31.1 0.0 7.6e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KNZ72799.1 - 5.3e-05 22.8 0.0 0.002 17.7 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KNZ72799.1 - 0.00085 18.8 0.1 1.3 8.5 0.0 3.1 4 0 0 4 4 4 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KNZ72799.1 - 0.098 12.7 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_32 PF13654.1 KNZ72799.1 - 0.12 10.9 0.2 0.23 10.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain Ank_4 PF13637.1 KNZ72800.1 - 8.3e-11 42.1 0.2 3.9e-05 24.0 0.1 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KNZ72800.1 - 3.2e-08 32.9 0.1 1.7e-07 30.6 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 KNZ72800.1 - 3.6e-08 33.6 0.1 7e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KNZ72800.1 - 4.8e-05 23.2 0.1 0.00046 20.1 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 KNZ72800.1 - 0.0003 20.9 0.1 0.00064 19.8 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Sybindin PF04099.7 KNZ72801.1 - 1.1e-16 60.7 0.0 1.7e-16 60.1 0.0 1.3 1 1 0 1 1 1 1 Sybindin-like family SNF2_N PF00176.18 KNZ72802.1 - 1.5e-64 217.6 0.0 2.1e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNZ72802.1 - 9.6e-15 54.2 0.1 3.7e-14 52.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ72802.1 - 1.7e-05 24.7 0.0 7.8e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HHH_3 PF12836.2 KNZ72802.1 - 0.0002 21.2 0.0 0.00051 19.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Mito_carr PF00153.22 KNZ72803.1 - 2.4e-13 49.5 0.0 1.9e-07 30.6 0.0 3.3 2 1 0 2 2 2 2 Mitochondrial carrier protein DUF1365 PF07103.6 KNZ72804.1 - 2.6e-23 82.3 0.0 4.5e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) zf-CCCH PF00642.19 KNZ72806.1 - 0.00015 21.3 4.8 0.0004 19.9 3.3 1.8 1 1 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 KNZ72806.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alg14 PF08660.6 KNZ72807.1 - 1.3e-49 168.4 0.0 1.8e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TPR_1 PF00515.23 KNZ72808.1 - 1.2e-24 84.8 8.8 9.2e-05 21.8 1.2 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ72808.1 - 2.7e-22 78.1 7.3 5.2e-10 38.8 1.8 5.6 5 1 1 6 6 6 3 TPR repeat APC8 PF04049.8 KNZ72808.1 - 1.8e-18 66.6 0.0 6.5e-18 64.8 0.0 1.9 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.1 KNZ72808.1 - 2.3e-18 64.5 2.7 0.0023 17.6 0.0 7.5 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ72808.1 - 1e-17 62.5 18.5 0.015 15.1 0.1 8.4 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ72808.1 - 2.1e-17 62.0 9.7 0.0071 16.8 0.1 8.8 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ72808.1 - 3.5e-13 49.2 16.5 2.7e-06 27.2 0.3 5.3 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ72808.1 - 8e-13 48.6 20.1 2.3e-05 24.9 0.3 7.5 6 3 2 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ72808.1 - 1.3e-10 40.5 1.5 0.14 12.3 0.0 6.5 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ72808.1 - 4.8e-09 35.3 13.9 0.41 10.5 0.0 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat Apc3 PF12895.2 KNZ72808.1 - 4e-07 30.0 14.2 0.0015 18.6 2.5 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KNZ72808.1 - 6.7e-06 25.8 13.4 0.00012 21.8 1.5 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ72808.1 - 2.1e-05 24.7 9.4 0.67 10.3 0.0 6.2 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ72808.1 - 0.0004 20.6 5.4 17 6.1 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.1 KNZ72808.1 - 0.0013 17.8 6.3 0.0029 16.7 2.4 2.6 2 1 0 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.5 KNZ72808.1 - 0.0094 14.7 0.0 0.12 11.0 0.0 2.3 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 KNZ72808.1 - 0.22 11.5 5.1 2.1 8.4 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 KNZ72808.1 - 0.67 9.8 5.3 0.75 9.7 0.1 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain GLTSCR1 PF15249.1 KNZ72809.1 - 1.1e-21 76.9 0.4 1.7e-21 76.3 0.3 1.3 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region Voltage_CLC PF00654.15 KNZ72810.1 - 1.7e-90 303.6 19.9 1.7e-90 303.6 13.8 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KNZ72810.1 - 0.0039 16.9 0.0 0.0093 15.7 0.0 1.6 1 0 0 1 1 1 1 CBS domain TAT_signal PF10518.4 KNZ72810.1 - 5.5 7.2 7.9 0.9 9.7 0.3 2.9 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence LSM PF01423.17 KNZ72811.1 - 1.2e-11 43.9 0.3 1.6e-11 43.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KNZ72811.1 - 0.008 16.0 0.1 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain E3_binding PF02817.12 KNZ72811.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 e3 binding domain DUF1674 PF07896.7 KNZ72812.1 - 1.3e-12 47.6 0.3 1.9e-12 47.1 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Selenoprotein_S PF06936.6 KNZ72812.1 - 0.11 12.0 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Fungal_trans PF04082.13 KNZ72813.1 - 2.4e-22 79.0 1.5 2.7e-22 78.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ72813.1 - 2e-09 37.1 13.3 4e-09 36.2 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KNZ72813.1 - 0.03 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain Ribosomal_S8e PF01201.17 KNZ72814.1 - 3.5e-40 137.2 3.0 6.3e-40 136.3 2.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 KNZ72814.1 - 0.043 13.7 1.3 0.045 13.6 0.1 1.5 2 0 0 2 2 2 0 Mer2 Yip1 PF04893.12 KNZ72815.1 - 1.3e-05 24.7 11.7 1.9e-05 24.2 8.1 1.3 1 0 0 1 1 1 1 Yip1 domain CbtB PF09489.5 KNZ72815.1 - 0.17 11.8 0.6 22 5.0 0.1 2.5 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) UPF0203 PF05254.7 KNZ72817.1 - 0.0081 15.9 0.6 0.081 12.7 0.3 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 KNZ72817.1 - 0.02 14.6 1.3 0.052 13.3 0.3 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 KNZ72817.1 - 0.11 12.3 0.2 0.16 11.9 0.2 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DUF1746 PF08508.5 KNZ72818.1 - 2.1e-05 24.4 0.8 6.2e-05 22.9 0.6 1.8 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Tetraspannin PF00335.15 KNZ72819.1 - 9.8e-07 28.2 9.9 3.9e-06 26.2 6.9 1.8 1 1 0 1 1 1 1 Tetraspanin family DUF2970 PF11174.3 KNZ72819.1 - 0.055 13.0 0.2 0.055 13.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) TerC PF03741.11 KNZ72819.1 - 2.3 7.6 10.0 0.03 13.7 1.9 1.5 2 0 0 2 2 2 0 Integral membrane protein TerC family Amidohydro_4 PF13147.1 KNZ72820.1 - 8.2e-19 68.6 0.8 4.2e-16 59.7 0.1 3.4 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KNZ72820.1 - 1.4e-11 44.0 0.7 4.2e-09 36.1 0.1 3.2 3 0 0 3 3 3 2 Amidohydrolase Amidohydro_1 PF01979.15 KNZ72820.1 - 1.5e-10 41.2 0.1 9.7e-08 32.0 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 KNZ72820.1 - 2.9e-06 26.7 0.6 0.00052 19.3 0.0 3.5 4 0 0 4 4 4 1 Amidohydrolase family DUF1183 PF06682.7 KNZ72821.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Rad10 PF03834.9 KNZ72823.1 - 8e-27 92.7 0.1 1.5e-26 91.8 0.1 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 KNZ72823.1 - 5.1e-09 36.1 0.0 1.6e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.2 KNZ72823.1 - 0.00019 21.2 0.0 0.00086 19.1 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.18 KNZ72823.1 - 0.089 12.5 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_3 PF12836.2 KNZ72823.1 - 0.096 12.6 0.0 0.27 11.1 0.0 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix motif Amidohydro_4 PF13147.1 KNZ72824.1 - 1.6e-20 74.3 1.3 6.2e-19 69.0 0.1 3.1 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 KNZ72824.1 - 9.2e-11 41.4 0.3 5.3e-09 35.7 0.0 2.9 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 KNZ72824.1 - 2.3e-07 30.8 0.4 4.5e-05 23.2 0.1 2.6 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 KNZ72824.1 - 1.8e-06 27.4 0.4 0.00013 21.3 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Abhydrolase_3 PF07859.8 KNZ72825.1 - 6.4e-26 91.2 0.0 8.7e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KNZ72825.1 - 5.7e-12 44.9 0.0 8.3e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DUF3128 PF11326.3 KNZ72826.1 - 5.9e-17 61.5 0.1 7.3e-17 61.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) MCM PF00493.18 KNZ72827.1 - 1.3e-139 464.6 0.3 1.8e-139 464.1 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KNZ72827.1 - 1.6e-31 109.4 30.3 1.6e-31 109.4 21.0 2.2 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KNZ72827.1 - 8.7e-17 61.7 0.1 2.9e-16 60.0 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KNZ72827.1 - 1.2e-07 31.0 0.0 3.8e-06 26.2 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KNZ72827.1 - 6.6e-06 25.9 0.0 1.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KNZ72827.1 - 0.0014 18.2 0.0 0.018 14.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KNZ72827.1 - 0.0016 17.9 0.1 0.013 14.9 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Yippee-Mis18 PF03226.9 KNZ72827.1 - 0.033 14.2 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CHCH PF06747.8 KNZ72828.1 - 3.6e-09 36.2 2.6 5.9e-09 35.6 1.8 1.3 1 0 0 1 1 1 1 CHCH domain Pkinase PF00069.20 KNZ72830.1 - 1e-52 178.9 0.0 1.2e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72830.1 - 1.1e-16 60.6 0.0 1.7e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ72830.1 - 3.7e-06 26.8 0.0 0.028 14.1 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pneumovirus_M2 PF06436.6 KNZ72830.1 - 0.053 12.7 0.1 0.2 10.8 0.0 1.9 3 0 0 3 3 3 0 Pneumovirus matrix protein 2 (M2) Sec7 PF01369.15 KNZ72831.1 - 7.4e-26 90.9 0.0 1.2e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Fe-ADH PF00465.14 KNZ72832.1 - 1e-60 205.3 0.0 1.3e-60 205.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KNZ72832.1 - 6.9e-15 55.0 0.0 1.4e-14 54.0 0.0 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cation_efflux PF01545.16 KNZ72833.1 - 1.4e-52 178.5 0.2 1.7e-52 178.2 0.1 1.1 1 0 0 1 1 1 1 Cation efflux family Lyase_aromatic PF00221.14 KNZ72834.1 - 1.5e-156 521.5 4.2 1.9e-156 521.1 2.9 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Tcp11 PF05794.8 KNZ72835.1 - 7.1e-08 31.5 0.0 0.00054 18.8 0.0 3.0 2 1 0 2 2 2 2 T-complex protein 11 Alba PF01918.16 KNZ72835.1 - 0.18 11.4 0.2 0.42 10.2 0.0 1.7 2 0 0 2 2 2 0 Alba Cnd3 PF12719.2 KNZ72836.1 - 2.3e-68 230.4 5.7 6.9e-68 228.8 2.9 2.5 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KNZ72836.1 - 2.8e-06 27.5 5.7 0.00061 20.0 0.0 4.2 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.17 KNZ72836.1 - 8e-06 25.5 3.3 0.031 14.3 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KNZ72836.1 - 9.9e-06 25.8 0.9 5.1 7.7 0.0 5.3 4 0 0 4 4 4 1 HEAT-like repeat Pneumo_att_G PF05539.6 KNZ72836.1 - 3.3 6.9 7.3 5.9 6.1 5.1 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Mg_trans_NIPA PF05653.9 KNZ72837.1 - 4.3e-16 58.7 11.2 1.4e-11 43.9 0.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Ssl1 PF04056.9 KNZ72838.1 - 1.2e-69 233.7 0.0 2.1e-69 233.0 0.0 1.4 1 1 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 KNZ72838.1 - 2.6e-11 43.9 0.0 4.1e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 KNZ72838.1 - 0.037 13.2 6.0 6.7 5.8 5.1 2.2 2 0 0 2 2 2 0 Transcription factor Tfb4 DUF4428 PF14471.1 KNZ72838.1 - 0.52 10.1 3.7 2 8.2 2.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) Hist_deacetyl PF00850.14 KNZ72839.1 - 4.7e-98 328.2 0.0 7.2e-98 327.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KNZ72839.1 - 2.1e-17 63.1 0.0 4.6e-17 61.9 0.0 1.6 2 0 0 2 2 2 1 Arb2 domain DUF3089 PF11288.3 KNZ72839.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Form_Nir_trans PF01226.12 KNZ72840.1 - 3.3e-68 229.2 21.6 8.9e-66 221.3 15.0 2.0 1 1 0 1 1 1 1 Formate/nitrite transporter RRM_2 PF04059.7 KNZ72841.1 - 3e-33 113.6 0.9 5.4e-33 112.8 0.6 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 KNZ72841.1 - 2.9e-05 23.6 0.9 0.021 14.4 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ72841.1 - 0.00012 21.9 1.0 0.00061 19.7 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S6 PF01250.12 KNZ72842.1 - 2.7e-07 30.3 0.0 3.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Cpn60_TCP1 PF00118.19 KNZ72843.1 - 7.4e-148 493.1 0.2 1e-147 492.7 0.2 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Amidohydro_2 PF04909.9 KNZ72845.1 - 0.00012 21.7 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase IncA PF04156.9 KNZ72846.1 - 0.0066 16.0 8.9 0.015 14.8 6.2 1.5 1 0 0 1 1 1 1 IncA protein DUF342 PF03961.8 KNZ72846.1 - 1.1 7.5 6.9 1.8 6.9 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 KNZ72846.1 - 3 8.2 6.1 7.4 6.9 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 KNZ72846.1 - 3.6 6.5 9.8 6.3 5.7 6.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 KNZ72846.1 - 5.8 6.5 13.5 11 5.6 9.4 1.3 1 0 0 1 1 1 0 Mnd1 family DivIVA PF05103.8 KNZ72846.1 - 10 6.2 14.7 21 5.1 10.2 1.5 1 0 0 1 1 1 0 DivIVA protein MIF4G PF02854.14 KNZ72847.1 - 3.8e-51 173.4 0.6 1.4e-29 102.9 0.0 3.6 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 KNZ72847.1 - 1.5e-25 89.9 8.3 1.5e-25 89.9 5.8 2.6 2 0 0 2 2 2 1 Up-frameshift suppressor 2 SNase PF00565.12 KNZ72848.1 - 1.4e-58 195.7 0.0 3.8e-21 75.3 0.0 6.2 5 1 0 5 5 5 4 Staphylococcal nuclease homologue TUDOR PF00567.19 KNZ72848.1 - 3e-08 33.5 0.0 2e-05 24.4 0.0 2.5 1 1 1 2 2 2 2 Tudor domain HAD_2 PF13419.1 KNZ72849.1 - 1.9e-16 60.7 0.0 2.4e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KNZ72849.1 - 1.8e-11 43.5 0.0 2.8e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KNZ72849.1 - 0.00021 21.7 0.0 0.00026 21.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SET PF00856.23 KNZ72850.1 - 3.5e-10 40.4 0.2 3.5e-10 40.4 0.1 3.5 3 1 0 3 3 3 1 SET domain ubiquitin PF00240.18 KNZ72851.1 - 7e-171 553.9 29.3 7.6e-34 114.9 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 KNZ72851.1 - 1.7e-96 315.9 28.5 8.1e-19 67.0 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KNZ72851.1 - 1.2e-29 102.4 14.3 0.00023 21.3 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KNZ72851.1 - 5.1e-26 91.2 1.9 0.0025 17.5 0.0 5.0 5 0 0 5 5 5 5 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KNZ72851.1 - 6.4e-17 61.4 5.4 0.16 11.8 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KNZ72851.1 - 1.1e-16 60.8 3.7 0.16 12.1 0.0 5.2 1 1 4 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KNZ72851.1 - 3e-13 49.6 0.0 2 8.4 0.0 5.8 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 KNZ72851.1 - 1.1e-08 34.4 1.9 1.5 7.9 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase FlgD_ig PF13860.1 KNZ72851.1 - 2.4e-08 33.5 8.1 4.6 7.0 0.0 5.3 5 0 0 5 5 5 4 FlgD Ig-like domain TUG-UBL1 PF11470.3 KNZ72851.1 - 7.6e-07 28.9 8.5 9 6.3 0.0 5.2 5 0 0 5 5 5 0 GLUT4 regulating protein TUG Big_3_3 PF13750.1 KNZ72851.1 - 6.8e-05 22.3 0.0 25 4.2 0.0 4.9 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 KNZ72851.1 - 9.8e-05 22.6 1.3 99 3.3 0.0 5.1 5 0 0 5 5 5 0 ACT domain Plexin_cytopl PF08337.7 KNZ72851.1 - 0.0041 15.4 18.7 5 5.3 0.2 6.7 6 4 0 6 6 6 4 Plexin cytoplasmic RasGAP domain CTDII PF01556.13 KNZ72851.1 - 0.018 14.8 19.9 11 6.0 0.3 5.6 1 1 3 5 5 5 0 DnaJ C terminal domain Tash_PEST PF07708.6 KNZ72851.1 - 0.025 14.4 38.3 4.5 7.3 1.2 5.3 5 0 0 5 5 5 0 Tash protein PEST motif GABP-alpha PF11620.3 KNZ72851.1 - 0.077 12.9 11.0 67 3.5 0.1 4.9 5 0 0 5 5 5 0 GA-binding protein alpha chain DUF3781 PF12636.2 KNZ72851.1 - 4.1 7.4 10.6 1.6e+02 2.3 0.1 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) FERM_N PF09379.5 KNZ72851.1 - 5.7 7.0 18.0 77 3.4 0.2 6.9 5 5 0 5 5 5 0 FERM N-terminal domain Nop25 PF09805.4 KNZ72852.1 - 7.9e-19 68.0 23.7 7.9e-19 68.0 16.4 2.4 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Oest_recep PF02159.10 KNZ72852.1 - 0.082 13.0 0.9 0.13 12.3 0.1 1.7 1 1 0 2 2 2 0 Oestrogen receptor V-SNARE_C PF12352.3 KNZ72853.1 - 3.5e-16 59.0 0.4 3.5e-16 59.0 0.3 2.5 3 1 1 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KNZ72853.1 - 0.01 15.5 1.9 0.07 12.8 0.0 2.6 2 1 1 3 3 3 0 Sec20 Scaffolding_pro PF11418.3 KNZ72853.1 - 0.012 15.8 0.3 0.024 14.9 0.2 1.5 1 1 0 1 1 1 0 Phi29 scaffolding protein DHC_N1 PF08385.7 KNZ72853.1 - 0.042 12.2 0.1 0.057 11.7 0.1 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 TPR_MLP1_2 PF07926.7 KNZ72853.1 - 0.095 12.4 2.8 0.14 11.9 1.9 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 KNZ72853.1 - 0.16 11.6 1.7 1.8 8.3 0.0 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper DivIVA PF05103.8 KNZ72853.1 - 0.3 11.1 4.7 0.18 11.8 2.1 1.5 2 0 0 2 2 2 0 DivIVA protein Plasmid_RAQPRD PF09686.5 KNZ72853.1 - 0.59 10.2 5.2 0.85 9.7 1.1 2.6 3 0 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Lactamase_B PF00753.22 KNZ72854.1 - 2.3e-06 27.3 0.2 3.8e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KNZ72854.1 - 9.7e-05 21.9 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain E1-E2_ATPase PF00122.15 KNZ72855.1 - 1e-26 93.4 0.0 2.3e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KNZ72855.1 - 1.5e-24 87.2 0.0 2.7e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KNZ72855.1 - 1.4e-20 74.6 0.0 8.7e-20 72.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 KNZ72855.1 - 1.9e-16 60.0 0.1 5.2e-16 58.5 0.1 1.8 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase_like2 PF13246.1 KNZ72855.1 - 4.7e-05 23.2 0.1 0.00011 22.0 0.1 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KNZ72855.1 - 0.0014 18.0 0.0 0.0033 16.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KNZ72855.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase adh_short_C2 PF13561.1 KNZ72856.1 - 2.6e-23 83.0 0.0 3.7e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KNZ72856.1 - 1.2e-16 61.1 0.0 1.7e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ72856.1 - 1.5e-07 31.2 0.0 2.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.1 KNZ72856.1 - 0.0025 18.1 0.0 0.0049 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DinI PF06183.8 KNZ72856.1 - 0.065 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 DinI-like family DUF4443 PF14544.1 KNZ72856.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) p450 PF00067.17 KNZ72857.1 - 4.7e-53 180.3 0.2 5.6e-53 180.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Troponin PF00992.15 KNZ72857.1 - 0.017 15.1 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Troponin FKBP_C PF00254.23 KNZ72858.1 - 5.9e-31 106.3 0.1 1.3e-30 105.2 0.1 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RNase_H2-Ydr279 PF09468.5 KNZ72858.1 - 0.13 11.4 7.7 0.19 10.9 5.4 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) YL1 PF05764.8 KNZ72858.1 - 0.18 11.3 21.4 0.26 10.8 14.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein GAGA_bind PF06217.7 KNZ72858.1 - 0.48 10.3 6.6 0.66 9.8 4.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Borrelia_P83 PF05262.6 KNZ72858.1 - 1.1 7.4 17.3 1.6 6.9 12.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.7 KNZ72858.1 - 1.3 8.8 14.3 1.9 8.2 9.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ARPC4 PF05856.7 KNZ72859.1 - 2e-71 238.8 3.1 2.2e-71 238.7 2.2 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF968 PF06147.6 KNZ72859.1 - 0.082 12.7 0.1 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF968) Ten1_2 PF15490.1 KNZ72860.1 - 0.00032 20.2 0.0 0.00035 20.1 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit DUF3252 PF11623.3 KNZ72862.1 - 0.13 11.6 0.0 0.34 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3252) Ribosomal_S7 PF00177.16 KNZ72863.1 - 9.8e-41 138.7 0.7 1.2e-40 138.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e IncA PF04156.9 KNZ72864.1 - 0.0035 16.9 6.7 0.0035 16.9 4.7 1.6 2 0 0 2 2 2 1 IncA protein Cep57_MT_bd PF06657.8 KNZ72864.1 - 0.011 15.6 0.6 0.011 15.6 0.4 2.5 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 APG6 PF04111.7 KNZ72864.1 - 0.04 12.9 3.6 0.053 12.5 2.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Filament PF00038.16 KNZ72864.1 - 0.11 11.8 10.7 0.024 14.1 5.2 1.4 2 0 0 2 2 2 0 Intermediate filament protein TMF_DNA_bd PF12329.3 KNZ72864.1 - 0.15 11.8 3.4 0.34 10.7 2.3 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding CHASE3 PF05227.8 KNZ72864.1 - 0.72 9.5 9.8 1.5 8.5 4.1 2.4 1 1 1 2 2 2 0 CHASE3 domain YscO PF07321.7 KNZ72864.1 - 7.6 6.3 16.7 2.9 7.6 7.7 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO SNF2_N PF00176.18 KNZ72866.1 - 3.4e-63 213.2 0.0 4.9e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KNZ72866.1 - 1e-15 57.5 0.0 2.2e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.13 KNZ72866.1 - 1.8e-10 40.9 0.0 3.8e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C3HC4_2 PF13923.1 KNZ72866.1 - 2e-09 37.3 7.0 4.2e-09 36.2 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ72866.1 - 3.7e-08 32.8 6.4 8.8e-08 31.6 4.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ72866.1 - 4.6e-08 32.7 5.4 9.6e-08 31.7 3.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KNZ72866.1 - 5.7e-08 32.3 3.1 1.1e-07 31.3 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 KNZ72866.1 - 2e-07 30.7 0.0 4.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KNZ72866.1 - 3e-06 26.8 4.1 5.8e-06 25.9 2.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KNZ72866.1 - 8.9e-05 22.2 7.6 0.00024 20.9 5.3 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KNZ72866.1 - 0.0015 18.5 1.2 0.0035 17.4 0.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger ResIII PF04851.10 KNZ72866.1 - 0.004 16.9 0.3 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.1 KNZ72866.1 - 0.12 12.0 6.7 0.29 10.8 4.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 KNZ72866.1 - 0.28 11.0 2.2 0.66 9.8 1.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KNZ72866.1 - 1.2 8.7 4.3 2.8 7.5 3.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Acetyltransf_3 PF13302.1 KNZ72867.1 - 1.7e-18 67.1 0.0 2.2e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ72867.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KNZ72867.1 - 0.0029 17.5 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KNZ72867.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain F-box-like PF12937.2 KNZ72868.1 - 4.6e-09 35.8 2.8 1.3e-08 34.4 1.9 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ72868.1 - 0.00044 19.8 0.9 0.0013 18.3 0.6 1.8 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 KNZ72869.1 - 6.2e-33 111.4 11.0 1.2e-06 28.1 0.0 7.0 7 1 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 KNZ72869.1 - 2.3e-05 23.9 0.4 0.00081 18.9 0.1 2.7 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.16 KNZ72869.1 - 5.9e-05 22.4 0.0 0.55 9.8 0.0 3.7 3 0 0 3 3 3 2 PQQ enzyme repeat Me-amine-dh_H PF06433.6 KNZ72869.1 - 0.027 13.1 0.0 0.15 10.7 0.0 2.0 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) LSM PF01423.17 KNZ72870.1 - 6.8e-14 51.1 0.2 1.1e-13 50.5 0.2 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KNZ72870.1 - 0.016 15.0 0.1 0.021 14.7 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Ribosomal_S8e PF01201.17 KNZ72871.1 - 3.9e-50 169.3 0.9 6.4e-50 168.7 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e UDPGP PF01704.13 KNZ72872.1 - 3.6e-148 493.5 0.0 4.1e-148 493.3 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase UDPGP PF01704.13 KNZ72873.1 - 4.4e-178 592.0 1.0 5.2e-178 591.8 0.7 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 KNZ72873.1 - 0.017 13.7 0.1 0.15 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4301) Metallophos PF00149.23 KNZ72874.1 - 3e-13 49.6 0.6 4.2e-12 45.8 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KNZ72874.1 - 0.00068 19.5 0.0 0.0014 18.5 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CPSase_sm_chain PF00988.17 KNZ72875.1 - 1.7e-44 150.5 0.0 4e-44 149.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KNZ72875.1 - 1.5e-34 119.1 0.0 3e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KNZ72875.1 - 3.6e-07 29.8 0.0 1.5e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 KNZ72875.1 - 0.0083 15.5 0.2 0.033 13.6 0.0 2.0 2 0 0 2 2 2 1 DJ-1/PfpI family BSD PF03909.12 KNZ72876.1 - 1.7e-08 34.0 0.0 3.5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 BSD domain MDMPI_N PF11716.3 KNZ72876.1 - 0.051 13.9 1.7 3.1 8.2 0.0 3.0 3 0 0 3 3 3 0 Mycothiol maleylpyruvate isomerase N-terminal domain Metallophos PF00149.23 KNZ72877.1 - 4.2e-06 26.2 0.0 1.8e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Scs3p PF10261.4 KNZ72878.1 - 2.5e-40 138.0 12.4 1.4e-38 132.3 8.6 2.2 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 KNZ72878.1 - 0.00021 20.9 2.3 0.00021 20.9 1.6 2.3 2 1 0 2 2 2 1 PAP2 superfamily ALAD PF00490.16 KNZ72879.1 - 9.4e-115 382.9 0.0 1e-114 382.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Pkinase PF00069.20 KNZ72880.1 - 8.2e-48 162.8 0.0 1.2e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72880.1 - 3.1e-31 108.4 0.0 8.2e-31 107.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ72880.1 - 0.02 13.8 0.0 0.036 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KNZ72880.1 - 0.025 14.3 0.6 0.77 9.4 0.0 2.4 1 1 0 2 2 2 0 Phosphotransferase enzyme family Homeobox PF00046.24 KNZ72881.1 - 2.3e-18 65.5 0.6 4.2e-18 64.6 0.4 1.5 1 0 0 1 1 1 1 Homeobox domain Aldo_ket_red PF00248.16 KNZ72882.1 - 2.1e-51 174.4 0.0 2.5e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family bZIP_2 PF07716.10 KNZ72883.1 - 0.054 13.3 2.0 0.21 11.4 0.1 2.2 2 0 0 2 2 2 0 Basic region leucine zipper RNA_pol_3_Rpc31 PF11705.3 KNZ72883.1 - 0.14 12.1 0.1 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BAG PF02179.11 KNZ72884.1 - 1.6e-12 47.3 0.0 2.1e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 KNZ72884.1 - 3.4e-06 26.3 0.0 5.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family TSKS PF15358.1 KNZ72884.1 - 0.038 12.1 0.0 0.039 12.1 0.0 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Pkinase PF00069.20 KNZ72885.1 - 3.6e-52 177.1 0.0 5.2e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72885.1 - 3.7e-36 124.5 0.0 6.6e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ72885.1 - 1.3e-07 30.8 0.0 2.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ72885.1 - 0.0014 18.4 0.1 0.086 12.5 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family tRNA-synt_1 PF00133.17 KNZ72886.1 - 2.1e-220 732.8 0.0 5.6e-220 731.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KNZ72886.1 - 2.1e-27 95.7 0.1 3.8e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KNZ72886.1 - 2.8e-17 62.4 0.2 1.4e-05 23.9 0.1 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KNZ72886.1 - 0.027 13.6 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain zf-C2H2_jaz PF12171.3 KNZ72887.1 - 2.9e-07 30.4 0.1 5.2e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KNZ72887.1 - 3.6e-05 23.8 0.1 6.2e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 KNZ72887.1 - 0.002 17.8 2.3 0.002 17.8 1.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-DBF PF07535.7 KNZ72887.1 - 0.0043 16.6 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 DBF zinc finger DUF3340 PF11818.3 KNZ72887.1 - 0.37 10.7 15.1 0.19 11.6 1.2 2.3 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) DUF4660 PF15559.1 KNZ72887.1 - 0.65 10.1 6.5 0.41 10.7 1.9 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4660) EXS PF03124.9 KNZ72888.1 - 2.7e-78 263.4 19.1 3.1e-78 263.2 13.2 1.0 1 0 0 1 1 1 1 EXS family 2-Hacid_dh_C PF02826.14 KNZ72889.1 - 2.7e-45 153.6 0.0 4.1e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KNZ72889.1 - 2.5e-16 59.3 0.0 3.3e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KNZ72889.1 - 1.3e-06 28.3 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Bromodomain PF00439.20 KNZ72890.1 - 1.5e-26 92.1 0.2 2.7e-26 91.2 0.2 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KNZ72890.1 - 8.3e-09 35.5 0.2 3.5e-08 33.4 0.2 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ72890.1 - 7.9e-07 29.0 0.1 2e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KNZ72890.1 - 0.018 15.1 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TFIIF_alpha PF05793.7 KNZ72890.1 - 2.7 6.2 6.7 4.1 5.6 4.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pro_isomerase PF00160.16 KNZ72891.1 - 1.2e-46 158.7 0.3 1.5e-46 158.4 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD p450 PF00067.17 KNZ72892.1 - 7.9e-53 179.5 0.0 1.2e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DEAD PF00270.24 KNZ72893.1 - 3.8e-36 124.1 0.0 6.5e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KNZ72893.1 - 7.5e-18 63.8 0.3 1.4e-17 63.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KNZ72893.1 - 8e-16 57.6 0.0 1.9e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ72893.1 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MOZ_SAS PF01853.13 KNZ72894.1 - 1.5e-82 275.4 0.5 2.1e-82 274.9 0.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KNZ72894.1 - 5.2e-17 61.2 0.0 1.1e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain HTH_Mga PF08280.6 KNZ72894.1 - 0.00051 19.7 0.3 0.0012 18.5 0.2 1.5 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Acetyltransf_1 PF00583.19 KNZ72894.1 - 0.069 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C2H2 PF00096.21 KNZ72894.1 - 0.14 12.5 3.8 0.17 12.2 1.2 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type LAG1-DNAbind PF09271.6 KNZ72896.1 - 8.2e-34 117.0 0.0 1.4e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 KNZ72896.1 - 4.8e-23 81.6 0.0 9.4e-21 74.2 0.0 3.0 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain Pacs-1 PF10254.4 KNZ72897.1 - 0.95 8.0 3.1 1.1 7.7 1.6 1.4 1 1 0 1 1 1 0 PACS-1 cytosolic sorting protein Pkinase PF00069.20 KNZ72899.1 - 1.4e-53 181.6 0.1 2.8e-53 180.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72899.1 - 2.4e-23 82.5 0.1 3.9e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ72899.1 - 0.00037 20.3 0.0 0.00037 20.3 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 KNZ72899.1 - 0.00092 18.6 0.9 0.0021 17.4 0.6 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KNZ72899.1 - 0.032 13.8 1.9 0.16 11.4 0.0 2.5 2 1 1 3 3 3 0 Choline/ethanolamine kinase Put_Phosphatase PF06888.7 KNZ72900.1 - 8.4e-42 142.9 1.2 1.3e-39 135.7 0.0 2.4 2 1 0 2 2 2 1 Putative Phosphatase BSD PF03909.12 KNZ72901.1 - 4.5e-16 58.3 0.0 1.1e-12 47.5 0.0 2.5 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 KNZ72901.1 - 0.094 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain CASP_C PF08172.7 KNZ72902.1 - 2.6e-66 223.1 0.1 2.6e-66 223.1 0.0 3.8 2 1 0 4 4 4 1 CASP C terminal AKNA PF12443.3 KNZ72902.1 - 0.18 11.8 22.5 0.12 12.3 1.0 5.0 3 1 2 5 5 5 0 AT-hook-containing transcription factor DUF4250 PF14056.1 KNZ72902.1 - 0.18 11.5 8.2 26 4.6 0.9 4.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) GnsAB PF08178.6 KNZ72902.1 - 0.99 9.1 8.4 8.2 6.1 0.6 3.1 2 0 0 2 2 2 0 GnsA/GnsB family Ribosomal_S9 PF00380.14 KNZ72903.1 - 8e-32 110.0 0.1 1.6e-31 109.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BRE1 PF08647.6 KNZ72904.1 - 1.3e-18 66.7 11.7 1.3e-18 66.7 8.1 5.9 2 2 4 6 6 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4 PF00097.20 KNZ72904.1 - 2.2e-07 30.3 9.6 4.6e-07 29.3 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ72904.1 - 2.4e-07 30.6 9.7 6.5e-07 29.2 6.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ72904.1 - 4.8e-06 26.1 9.1 1.3e-05 24.8 6.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KNZ72904.1 - 7.8e-06 25.4 6.5 1.9e-05 24.2 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ72904.1 - 7.3e-05 22.5 7.9 0.00015 21.5 5.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 KNZ72904.1 - 0.0027 17.4 3.7 0.0054 16.4 2.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Reo_sigmaC PF04582.7 KNZ72904.1 - 0.0076 15.4 16.3 0.01 15.0 0.8 4.0 3 2 1 4 4 4 3 Reovirus sigma C capsid protein zf-rbx1 PF12678.2 KNZ72904.1 - 0.013 15.6 0.9 0.03 14.4 0.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KNZ72904.1 - 0.033 13.8 4.0 0.11 12.2 2.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger HxlR PF01638.12 KNZ72904.1 - 0.045 13.3 0.4 0.18 11.4 0.1 2.2 2 0 0 2 2 2 0 HxlR-like helix-turn-helix DUF1272 PF06906.6 KNZ72904.1 - 0.15 11.9 4.6 0.39 10.5 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.1 KNZ72904.1 - 0.43 10.4 7.5 0.98 9.3 5.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KNZ72904.1 - 0.84 9.2 10.0 2.9 7.5 4.5 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ureidogly_hydro PF04115.7 KNZ72905.1 - 2.1e-43 147.5 0.0 2.8e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Allantoicase PF03561.10 KNZ72905.1 - 2.4e-37 127.7 0.7 3.6e-37 127.1 0.5 1.3 1 0 0 1 1 1 1 Allantoicase repeat Methyltransf_26 PF13659.1 KNZ72906.1 - 3.1e-12 46.5 0.0 5.4e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ72906.1 - 2.4e-10 40.9 0.0 3.9e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ72906.1 - 5.3e-07 29.3 0.0 2.3e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ72906.1 - 9.5e-05 21.8 0.2 0.00072 18.9 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KNZ72906.1 - 0.00031 20.4 0.0 0.00059 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KNZ72906.1 - 0.00034 19.8 0.0 0.00057 19.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 KNZ72906.1 - 0.0043 17.3 0.0 0.0075 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KNZ72906.1 - 0.1 12.1 0.1 0.35 10.4 0.1 1.8 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_10 PF05971.7 KNZ72906.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF890) Zn_clus PF00172.13 KNZ72907.1 - 0.00023 20.9 11.8 0.00049 19.9 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 KNZ72907.1 - 0.0034 17.1 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold Frankia_peptide PF14407.1 KNZ72907.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. PRA1 PF03208.14 KNZ72908.1 - 2.3e-36 124.4 0.9 2.7e-36 124.2 0.6 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF202 PF02656.10 KNZ72908.1 - 0.1 12.8 3.0 0.23 11.7 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF3040 PF11239.3 KNZ72908.1 - 0.85 9.7 4.3 2.9 7.9 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) APC_CDC26 PF10471.4 KNZ72909.1 - 0.0027 18.4 1.2 0.0037 17.9 0.8 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Asp-B-Hydro_N PF05279.6 KNZ72909.1 - 0.018 14.8 0.4 0.022 14.5 0.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TPR_11 PF13414.1 KNZ72910.1 - 1.3e-17 63.2 11.9 3e-10 39.6 0.9 3.4 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 KNZ72910.1 - 2.8e-17 61.4 7.6 3.1e-05 23.3 0.1 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ72910.1 - 6.8e-14 50.5 11.2 0.001 18.8 0.2 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ72910.1 - 1.7e-11 43.3 7.4 0.0065 16.5 0.3 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ72910.1 - 9.8e-11 41.3 9.4 0.00023 21.4 0.0 5.6 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ72910.1 - 5.4e-10 39.6 4.4 5.5e-06 26.8 0.2 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ72910.1 - 1.8e-09 37.3 10.3 1.5e-05 24.8 0.4 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ72910.1 - 9.7e-09 35.4 9.1 3.5e-07 30.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 KNZ72910.1 - 2.6e-06 27.4 6.2 0.073 13.2 0.6 3.7 2 1 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KNZ72910.1 - 1.1e-05 25.5 2.9 0.0026 17.8 0.3 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KNZ72910.1 - 0.00085 18.9 5.6 0.062 13.1 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ72910.1 - 0.0049 16.7 6.8 4.1 7.4 0.3 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ72910.1 - 0.0063 16.3 4.7 0.22 11.3 0.3 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ72910.1 - 0.34 10.8 5.0 24 5.0 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 KNZ72910.1 - 1 9.2 4.0 4.7 7.1 0.0 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain zf-C2H2 PF00096.21 KNZ72911.1 - 4.1e-13 48.8 12.5 0.00019 21.5 0.2 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ72911.1 - 5.6e-10 38.8 11.9 0.0008 19.5 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KNZ72911.1 - 9.1e-07 28.8 15.1 3.4e-05 23.9 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KNZ72911.1 - 0.00039 20.2 1.0 0.8 9.6 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KNZ72911.1 - 0.0062 16.7 4.7 2 8.7 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KNZ72911.1 - 0.024 14.7 1.8 0.88 9.7 0.6 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KNZ72911.1 - 0.15 12.2 5.1 1.1 9.4 1.6 2.4 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.13 KNZ72911.1 - 0.15 12.4 7.3 0.1 12.9 1.7 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger IBR PF01485.16 KNZ72911.1 - 0.33 10.8 7.3 4 7.3 3.0 2.3 1 1 1 2 2 2 0 IBR domain zf-BED PF02892.10 KNZ72911.1 - 1.9 8.3 8.1 0.25 11.1 1.9 2.2 2 0 0 2 2 2 0 BED zinc finger Abhydrolase_3 PF07859.8 KNZ72912.1 - 5.4e-30 104.5 0.0 1.4e-21 77.0 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold IF-2B PF01008.12 KNZ72913.1 - 2.4e-52 177.6 0.0 3.1e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family UBN2_2 PF14227.1 KNZ72914.1 - 1.4e-08 34.2 0.0 1.8e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ72914.1 - 2.2e-08 33.8 0.0 2.8e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TrbC_Ftype PF09673.5 KNZ72914.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein TNV_CP PF03898.8 KNZ72914.1 - 0.048 12.7 0.1 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein Asparaginase_2 PF01112.13 KNZ72915.1 - 1e-30 106.6 0.0 1.4e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Asparaginase Tfb4 PF03850.9 KNZ72916.1 - 3.3e-81 272.5 0.0 4e-81 272.3 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-met2 PF12907.2 KNZ72916.1 - 1.9 8.5 0.0 1.9 8.5 0.0 3.3 3 0 0 3 3 3 0 Zinc-binding Lamp PF01299.12 KNZ72916.1 - 5.9 5.9 7.1 6.5 5.8 3.4 1.8 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) SNF2_N PF00176.18 KNZ72917.1 - 5e-66 222.5 0.4 8.7e-66 221.7 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 KNZ72917.1 - 1.7e-26 92.3 0.4 7.4e-26 90.3 0.3 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Chromo PF00385.19 KNZ72917.1 - 5.3e-18 64.4 4.6 1.3e-14 53.6 0.6 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KNZ72917.1 - 2.4e-13 49.7 0.0 5.6e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1771 PF08590.5 KNZ72918.1 - 0.091 12.7 2.4 0.17 11.8 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Slu7 PF11708.3 KNZ72919.1 - 3.3e-83 279.1 12.1 3.3e-83 279.1 8.4 2.3 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor DUF2151 PF10221.4 KNZ72919.1 - 0.068 11.3 6.2 0.33 9.0 0.9 2.3 2 0 0 2 2 2 0 Cell cycle and development regulator TRL PF13146.1 KNZ72919.1 - 0.12 12.3 0.4 0.27 11.2 0.3 1.6 1 0 0 1 1 1 0 TRL-like protein family XPG_N PF00752.12 KNZ72920.1 - 3.9e-34 116.9 0.0 7.7e-34 115.9 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KNZ72920.1 - 7.1e-24 83.6 0.0 1.5e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 KNZ72920.1 - 1e-06 28.8 0.0 2.9e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 KNZ72920.1 - 0.018 15.2 0.0 0.079 13.1 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix domain Transposase_20 PF02371.11 KNZ72920.1 - 0.074 13.1 0.0 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family Fungal_trans PF04082.13 KNZ72922.1 - 2.2e-29 102.1 0.0 4.4e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ72922.1 - 0.15 12.0 1.3 0.32 10.9 0.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RNase_H2-Ydr279 PF09468.5 KNZ72923.1 - 9e-48 163.0 0.0 3.1e-47 161.2 0.0 1.8 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) MmgE_PrpD PF03972.9 KNZ72924.1 - 1.4e-158 527.7 0.0 1.6e-158 527.5 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family ATP-sulfurylase PF01747.12 KNZ72925.1 - 1e-87 293.0 0.2 1.4e-87 292.5 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 KNZ72925.1 - 8.5e-52 174.7 0.0 1.4e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.15 KNZ72925.1 - 1.7e-49 167.4 0.0 2.5e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.5 KNZ72925.1 - 0.045 12.9 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF4098 PF13345.1 KNZ72926.1 - 4.4 7.3 10.2 13 5.8 0.0 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4098) ERO1 PF04137.10 KNZ72927.1 - 1.8e-118 395.6 0.2 2.3e-118 395.3 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) KH_1 PF00013.24 KNZ72928.1 - 1.5e-72 239.1 31.9 3.6e-11 42.5 0.3 12.2 12 0 0 12 12 12 9 KH domain KH_3 PF13014.1 KNZ72928.1 - 1.5e-48 161.7 21.1 1.3e-07 31.1 0.1 11.8 11 0 0 11 11 11 8 KH domain KH_2 PF07650.12 KNZ72928.1 - 7.4e-11 41.4 19.7 0.0055 16.2 1.0 8.2 8 0 0 8 8 8 5 KH domain SLS PF14611.1 KNZ72928.1 - 2e-08 33.9 23.8 0.00077 18.9 0.0 7.0 6 3 1 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 KNZ72928.1 - 0.0007 19.1 13.4 0.99 9.0 0.1 6.8 7 0 0 7 7 7 2 KH domain BMC PF00936.14 KNZ72928.1 - 0.034 13.8 25.4 0.81 9.4 1.0 6.7 7 0 0 7 7 7 0 BMC domain RRM_1 PF00076.17 KNZ72929.1 - 5.6e-09 35.5 0.0 7.1e-06 25.5 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ72929.1 - 1.4e-08 34.5 0.0 4.5e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 KNZ72929.1 - 1.1e-07 31.3 0.1 2.4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Surp module RRM_5 PF13893.1 KNZ72929.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 KNZ72930.1 - 2.3e-27 95.6 0.3 1.7e-21 76.5 0.2 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase TPR_11 PF13414.1 KNZ72930.1 - 4e-24 84.0 6.3 6.4e-15 54.5 0.2 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KNZ72930.1 - 3.8e-16 57.9 4.0 2.8e-07 29.8 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat PPP5 PF08321.7 KNZ72930.1 - 4.8e-14 52.1 0.0 9.6e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_2 PF07719.12 KNZ72930.1 - 1.4e-12 46.4 3.8 0.00023 20.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ72930.1 - 3.5e-08 33.0 0.7 0.0042 17.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ72930.1 - 1.6e-07 31.0 0.1 0.011 15.6 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ72930.1 - 5.5e-05 23.4 1.9 0.031 14.6 1.2 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ72930.1 - 8.2e-05 23.1 3.2 0.0062 17.1 1.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ72930.1 - 9.6e-05 22.6 0.2 0.16 12.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ72930.1 - 0.0021 17.7 1.0 0.16 11.7 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KNZ72930.1 - 0.0075 16.3 1.2 0.024 14.7 0.7 2.0 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KNZ72930.1 - 0.02 13.9 0.5 0.11 11.5 0.2 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ72930.1 - 0.02 15.2 1.9 0.081 13.4 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ72930.1 - 0.052 13.4 0.2 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ72930.1 - 0.15 11.9 0.0 4.9 7.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat SLT PF01464.15 KNZ72931.1 - 4.9e-15 55.0 0.1 8.7e-15 54.2 0.1 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.15 KNZ72931.1 - 0.048 13.7 0.2 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Cyclin PF08613.6 KNZ72932.1 - 9.3e-09 35.8 0.0 1.8e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 Cyclin Cyclin_N PF00134.18 KNZ72932.1 - 0.024 14.2 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain Asp PF00026.18 KNZ72933.1 - 4.2e-44 151.0 0.5 5.3e-44 150.7 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNZ72933.1 - 5e-06 26.5 1.1 6.2e-05 23.0 0.6 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KNZ72933.1 - 0.0027 18.1 2.5 1.6 9.2 0.0 3.5 2 1 0 2 2 2 2 Aspartyl protease Zn_clus PF00172.13 KNZ72934.1 - 3.3e-07 30.1 6.7 5e-07 29.5 4.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KNZ72935.1 - 5.2e-61 206.0 0.0 6.1e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72935.1 - 4e-38 130.9 0.0 5e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ72935.1 - 1.6e-06 27.3 0.0 6.9e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Acetyltransf_1 PF00583.19 KNZ72936.1 - 6.3e-14 51.7 0.0 9.4e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KNZ72936.1 - 3.3e-09 36.7 0.1 1.1e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KNZ72936.1 - 6.9e-08 32.5 0.0 8.8e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KNZ72936.1 - 3e-07 30.4 0.0 3.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KNZ72936.1 - 0.00085 19.4 0.0 0.00095 19.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNZ72936.1 - 0.00086 19.4 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KNZ72936.1 - 0.0063 16.2 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Sugar_tr PF00083.19 KNZ72939.1 - 1.6e-27 96.2 30.1 3.5e-24 85.2 20.9 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ72939.1 - 2.6e-18 65.8 33.1 3.2e-18 65.5 21.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KNZ72939.1 - 2.8e-07 29.3 20.5 0.0061 15.0 0.6 3.1 2 1 0 3 3 3 3 MFS/sugar transport protein Transgly_assoc PF04226.8 KNZ72939.1 - 8.3 6.5 13.8 3.7 7.6 0.5 4.2 4 0 0 4 4 4 0 Transglycosylase associated protein Complex1_49kDa PF00346.14 KNZ72940.1 - 1.1e-112 375.5 0.0 1.4e-112 375.1 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 KNZ72940.1 - 0.066 11.9 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Pkinase PF00069.20 KNZ72941.1 - 7.9e-27 94.0 0.0 1.5e-26 93.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72941.1 - 7e-07 28.5 0.0 0.031 13.3 0.0 3.0 2 1 1 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 KNZ72941.1 - 0.023 13.6 0.0 2.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 KNZ72941.1 - 0.029 13.7 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KNZ72941.1 - 0.054 12.5 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metalloenzyme PF01676.13 KNZ72942.1 - 4.6e-75 252.2 1.0 6.1e-75 251.8 0.7 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 KNZ72942.1 - 2e-69 233.3 0.0 3.8e-69 232.4 0.0 1.5 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Sulfatase PF00884.18 KNZ72942.1 - 5.9e-07 28.9 0.1 3.8e-06 26.3 0.1 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KNZ72942.1 - 3.1e-06 26.7 0.0 5.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.7 KNZ72942.1 - 0.002 17.8 0.1 0.0048 16.5 0.1 1.7 1 0 0 1 1 1 1 PglZ domain CIMR PF00878.13 KNZ72943.1 - 1.9e-09 37.4 0.0 0.0015 18.2 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 KNZ72943.1 - 9.4e-07 28.3 0.3 3.4e-06 26.4 0.2 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 KNZ72943.1 - 0.0072 15.3 0.0 0.0095 14.9 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor PAT1 PF09770.4 KNZ72943.1 - 7.6 4.6 9.1 9.6 4.3 6.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NIF3 PF01784.13 KNZ72944.1 - 5.1e-49 167.0 0.1 3.9e-47 160.8 0.0 2.5 2 1 0 2 2 2 2 NIF3 (NGG1p interacting factor 3) ECH PF00378.15 KNZ72945.1 - 2.7e-45 154.3 0.0 3.4e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MEKHLA PF08670.6 KNZ72945.1 - 0.069 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 MEKHLA domain Peptidase_M76 PF09768.4 KNZ72946.1 - 1.9e-66 222.7 1.7 2.3e-66 222.4 1.2 1.1 1 0 0 1 1 1 1 Peptidase M76 family Dicty_spore_N PF04562.7 KNZ72946.1 - 0.28 11.4 2.2 1.9 8.7 0.2 2.3 1 1 1 2 2 2 0 Dictyostelium spore coat protein, N terminus GPI-anchored PF10342.4 KNZ72947.1 - 1.7e-07 31.5 0.6 1.7e-07 31.5 0.4 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glutaredoxin PF00462.19 KNZ72948.1 - 1e-14 54.2 0.1 1.3e-14 53.8 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 KNZ72948.1 - 0.00057 20.0 0.2 0.0012 18.9 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 KNZ72948.1 - 0.0058 16.4 0.0 0.0078 16.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 KNZ72948.1 - 0.0097 15.4 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF953 PF06110.6 KNZ72948.1 - 0.016 14.6 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.1 KNZ72948.1 - 0.02 14.8 0.1 0.043 13.8 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like Fmp27_SW PF10305.4 KNZ72948.1 - 0.068 13.6 0.0 0.076 13.4 0.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain GST_N_3 PF13417.1 KNZ72948.1 - 0.075 13.2 0.0 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF723 PF05265.8 KNZ72948.1 - 0.16 11.7 1.1 4.6 7.1 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF723) DPM3 PF08285.6 KNZ72949.1 - 3.3e-32 110.1 0.1 3.7e-32 110.0 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1903 PF08991.5 KNZ72950.1 - 2.9e-10 40.1 3.7 3.8e-10 39.7 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) Med10 PF09748.4 KNZ72950.1 - 0.087 12.6 0.0 0.093 12.5 0.0 1.0 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex HsbA PF12296.3 KNZ72953.1 - 7.6e-13 48.3 0.8 1.1e-12 47.8 0.6 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Dynamitin PF04912.9 KNZ72953.1 - 0.0059 15.4 0.0 0.0076 15.1 0.0 1.2 1 0 0 1 1 1 1 Dynamitin Terpene_synth_C PF03936.11 KNZ72953.1 - 0.086 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain RVT_1 PF00078.22 KNZ72956.1 - 0.0005 19.4 0.0 0.00057 19.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fasciclin PF02469.17 KNZ72959.1 - 4.2e-07 30.0 0.0 1e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain WEMBL PF05701.6 KNZ72959.1 - 0.071 11.5 0.0 0.084 11.3 0.0 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light PC4 PF02229.11 KNZ72959.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) ICMT PF04140.9 KNZ72960.1 - 4.9e-12 45.8 4.7 6.5e-12 45.4 0.6 2.5 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KNZ72960.1 - 3.6e-11 43.1 1.9 8.5e-10 38.6 0.4 2.6 2 1 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KNZ72960.1 - 3.8e-05 22.4 0.2 5.3e-05 21.9 0.1 1.3 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KNZ72960.1 - 0.011 15.1 0.5 0.021 14.1 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) HARP PF07443.8 KNZ72961.1 - 0.12 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 HepA-related protein (HARP) Aldo_ket_red PF00248.16 KNZ72962.1 - 1.2e-65 221.1 0.0 1.5e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Adap_comp_sub PF00928.16 KNZ72963.1 - 6.4e-23 81.1 0.0 1e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KNZ72963.1 - 2.3e-06 27.3 0.3 3.7e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4300 PF14133.1 KNZ72964.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) DUF350 PF03994.9 KNZ72966.1 - 0.095 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) TPR_10 PF13374.1 KNZ72967.1 - 8.9e-26 89.0 0.3 3.3e-10 39.5 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ72967.1 - 1e-21 76.6 0.3 1.9e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ72967.1 - 2.7e-08 33.3 0.0 0.025 14.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ72967.1 - 3.8e-05 24.2 0.0 0.72 10.6 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 KNZ72967.1 - 0.00019 21.5 1.7 6.6 7.4 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ72967.1 - 0.00093 19.4 0.6 0.1 12.9 0.3 3.3 2 2 2 4 4 4 1 Tetratricopeptide repeat DUF4404 PF14357.1 KNZ72967.1 - 0.0048 17.2 4.9 1.8 9.0 0.2 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF4404) TPR_11 PF13414.1 KNZ72967.1 - 0.019 14.5 0.0 0.3 10.7 0.0 2.4 2 2 0 2 2 2 0 TPR repeat DUF919 PF06034.6 KNZ72967.1 - 0.024 14.2 0.7 7.8 6.2 0.1 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) A2M PF00207.17 KNZ72967.1 - 0.03 13.9 0.0 0.95 9.0 0.0 2.7 1 1 1 2 2 2 0 Alpha-2-macroglobulin family C_GCAxxG_C_C PF09719.5 KNZ72967.1 - 0.065 13.0 0.1 17 5.2 0.0 3.0 3 0 0 3 3 3 0 Putative redox-active protein (C_GCAxxG_C_C) FAD_binding_8 PF08022.7 KNZ72967.1 - 0.073 12.9 0.1 0.48 10.3 0.0 2.1 1 1 1 2 2 2 0 FAD-binding domain Peptidase_C8 PF03569.8 KNZ72967.1 - 0.087 12.1 0.2 22 4.2 0.0 2.9 3 0 0 3 3 3 0 Peptidase family C8 RRM_1 PF00076.17 KNZ72968.1 - 4.8e-18 64.5 0.0 6.7e-18 64.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ72968.1 - 1.9e-15 56.5 0.0 3e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ72968.1 - 4.1e-09 36.1 0.0 5.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LEAP-2 PF07359.6 KNZ72969.1 - 0.044 13.4 0.3 0.12 11.9 0.2 1.8 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) CSTF2_hinge PF14327.1 KNZ72971.1 - 1.7e-08 34.3 3.7 1.7e-08 34.3 2.5 2.7 2 1 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 KNZ72971.1 - 8.8e-07 28.1 0.8 8.8e-07 28.1 0.6 2.4 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal DUF605 PF04652.11 KNZ72971.1 - 3.5 6.9 23.7 5.2 6.3 16.4 1.3 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KNZ72971.1 - 5.2 5.1 20.4 6.2 4.9 14.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Adaptin_N PF01602.15 KNZ72972.1 - 2.3e-91 306.6 7.3 4.1e-91 305.9 5.1 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 KNZ72972.1 - 1.2e-64 215.8 0.0 3e-64 214.5 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 KNZ72972.1 - 3.5e-57 192.0 0.0 9.3e-57 190.6 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 KNZ72972.1 - 6.3e-14 52.0 0.3 0.0057 16.9 0.0 5.2 2 1 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 KNZ72972.1 - 2.3e-07 30.8 6.7 0.012 15.4 0.2 5.3 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KNZ72972.1 - 0.00019 21.2 1.5 0.36 11.0 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat Arm_2 PF04826.8 KNZ72972.1 - 0.00025 20.2 1.0 0.54 9.3 0.0 3.6 3 1 1 4 4 4 2 Armadillo-like HEAT_EZ PF13513.1 KNZ72972.1 - 0.0025 18.2 0.0 3.6 8.2 0.0 4.7 4 1 1 5 5 5 1 HEAT-like repeat ParcG PF10274.4 KNZ72972.1 - 0.0072 16.2 2.1 0.73 9.7 0.0 3.0 3 1 0 3 3 3 1 Parkin co-regulated protein CBF PF03914.12 KNZ72972.1 - 0.54 9.7 3.4 2.9 7.3 0.8 2.8 2 1 0 2 2 2 0 CBF/Mak21 family Utp14 PF04615.8 KNZ72973.1 - 3.6e-166 554.4 58.1 3.6e-166 554.4 40.3 2.8 1 1 1 2 2 2 1 Utp14 protein TMP_2 PF06791.8 KNZ72973.1 - 0.032 13.8 1.5 0.041 13.4 0.1 1.8 2 0 0 2 2 2 0 Prophage tail length tape measure protein Pkinase PF00069.20 KNZ72974.1 - 3.3e-74 249.3 0.0 4.4e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ72974.1 - 6e-40 136.9 0.0 8.8e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 KNZ72974.1 - 6.7e-06 26.1 0.1 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 KNZ72974.1 - 7.7e-06 25.0 0.0 1.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KNZ72974.1 - 3.9e-05 23.0 0.0 7.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KNZ72974.1 - 0.00035 19.6 0.7 0.0062 15.6 0.5 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ72974.1 - 0.015 15.0 0.2 0.38 10.4 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family YukC PF10140.4 KNZ72974.1 - 0.12 10.9 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC MatE PF01554.13 KNZ72977.1 - 1.9e-38 131.6 23.0 2.3e-21 76.0 6.2 2.3 2 0 0 2 2 2 2 MatE Heme_oxygenase PF01126.15 KNZ72978.1 - 0.0076 15.8 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Heme oxygenase PhoU PF01895.14 KNZ72978.1 - 0.72 10.3 10.1 1.3 9.4 3.4 2.9 2 1 0 2 2 2 0 PhoU domain DUF3629 PF12302.3 KNZ72978.1 - 0.83 8.9 5.6 6.2 6.1 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3629) CDC37_N PF03234.9 KNZ72978.1 - 1.9 8.7 8.6 0.65 10.2 3.7 1.9 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Macoilin PF09726.4 KNZ72978.1 - 2.3 6.3 14.4 0.21 9.8 3.6 2.1 2 0 0 2 2 2 0 Transmembrane protein TBPIP PF07106.8 KNZ72978.1 - 6.3 6.3 13.4 1.9 7.9 3.9 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4404 PF14357.1 KNZ72978.1 - 8.8 6.8 12.5 13 6.2 3.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Asp PF00026.18 KNZ72979.1 - 5.6e-45 153.9 7.1 7.6e-45 153.5 4.9 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNZ72979.1 - 1.3e-06 28.4 1.5 1.7e-05 24.8 1.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KNZ72979.1 - 4.1e-06 27.1 3.5 3.4e-05 24.2 0.6 2.9 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 KNZ72979.1 - 0.042 13.4 0.0 0.18 11.3 0.0 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal WD40 PF00400.27 KNZ72982.1 - 1.3e-09 37.5 6.4 0.55 10.2 0.0 5.6 5 1 0 5 5 5 4 WD domain, G-beta repeat TP_methylase PF00590.15 KNZ72984.1 - 2.3e-41 141.8 1.0 3.6e-41 141.1 0.7 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.1 KNZ72984.1 - 1.3e-06 27.6 0.7 0.00021 20.5 0.1 2.6 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KNZ72984.1 - 5e-05 22.1 0.1 8.3e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.1 KNZ72984.1 - 0.00086 19.5 0.0 0.0034 17.5 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding SRP14 PF02290.10 KNZ72985.1 - 2.2e-23 81.9 0.0 4.7e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle 14kD protein DUF726 PF05277.7 KNZ72989.1 - 6.9e-120 400.0 0.6 9.1e-120 399.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 KNZ72989.1 - 0.0045 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KNZ72989.1 - 0.058 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Glyco_hydro_43 PF04616.9 KNZ72990.1 - 2.2e-27 95.9 0.0 2.7e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1115 PF06544.7 KNZ72991.1 - 1e-08 34.8 0.1 1.8e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) AKAP95 PF04988.7 KNZ72991.1 - 0.12 12.1 1.3 0.28 10.9 0.9 1.5 1 1 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) MtN3_slv PF03083.11 KNZ72992.1 - 0.069 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange MatE PF01554.13 KNZ72993.1 - 7.5e-32 110.1 28.0 4.7e-27 94.5 7.3 3.3 2 1 1 3 3 3 3 MatE Aminotran_1_2 PF00155.16 KNZ72994.1 - 6.4e-42 143.7 0.0 7.2e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KNZ72994.1 - 2.1e-06 27.0 0.2 3.4e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KNZ72994.1 - 8.6e-05 20.9 0.0 0.00013 20.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KNZ72994.1 - 0.0054 15.5 0.0 0.015 14.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KNZ72994.1 - 0.2 10.7 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Malic_M PF03949.10 KNZ72996.1 - 1.2e-75 254.3 0.0 1.6e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KNZ72996.1 - 3.1e-61 206.1 0.0 1.3e-60 204.0 0.0 1.9 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain MARVEL PF01284.18 KNZ72997.1 - 1.9e-06 27.7 17.6 2.3e-06 27.4 12.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain COQ7 PF03232.8 KNZ72997.1 - 0.026 13.9 0.2 0.05 13.0 0.0 1.5 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Tic20 PF09685.5 KNZ72997.1 - 0.65 9.9 19.3 1.3 9.0 0.8 2.1 1 1 1 2 2 2 0 Tic20-like protein DUF373 PF04123.8 KNZ72997.1 - 0.83 8.6 7.1 0.95 8.4 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2975 PF11188.3 KNZ72997.1 - 8.6 6.0 15.2 15 5.3 10.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) Fungal_trans PF04082.13 KNZ72998.1 - 1.7e-11 43.5 2.7 3.2e-11 42.5 1.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ72998.1 - 2.1e-05 24.3 10.2 5.5e-05 22.9 7.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2235 PF09994.4 KNZ72999.1 - 1.9e-77 260.3 0.0 3.9e-77 259.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KNZ72999.1 - 0.029 14.1 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_28 PF00295.12 KNZ73000.1 - 7.2e-44 150.0 4.4 1.3e-43 149.1 0.8 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Histone PF00125.19 KNZ73001.1 - 1.3e-29 102.0 0.8 1.9e-29 101.5 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNZ73001.1 - 3.5e-05 23.8 0.1 5.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KNZ73001.1 - 0.0036 17.3 0.1 0.0036 17.3 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KNZ73001.1 - 0.038 13.7 0.1 0.062 13.0 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated Cellulase PF00150.13 KNZ73002.1 - 2.2e-31 109.1 6.6 2.8e-31 108.7 4.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KNZ73002.1 - 2.3e-11 43.1 5.8 2.3e-11 43.1 4.1 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.12 KNZ73002.1 - 1.5e-07 30.6 0.0 2.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 KNZ73002.1 - 7.8e-06 26.2 0.0 1.9e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_10 PF00331.15 KNZ73002.1 - 0.0011 18.0 0.3 0.002 17.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.10 KNZ73002.1 - 0.0096 15.0 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase Hormone_recep PF00104.25 KNZ73003.1 - 0.018 14.1 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor zf-C2H2_4 PF13894.1 KNZ73004.1 - 8.9e-07 28.8 1.7 0.0019 18.3 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KNZ73004.1 - 0.0031 17.7 1.5 2 8.9 0.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 KNZ73004.1 - 0.023 14.3 2.0 0.079 12.6 1.4 1.9 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 KNZ73004.1 - 0.15 12.4 0.8 0.44 10.9 0.6 1.9 1 0 0 1 1 1 0 Zinc-finger double domain GFO_IDH_MocA PF01408.17 KNZ73005.1 - 1.3e-14 54.7 0.0 2.5e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KNZ73005.1 - 0.00014 21.5 0.1 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Imm-NTF2-2 PF15631.1 KNZ73005.1 - 0.11 12.4 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 NTF2 fold immunity protein F-box-like PF12937.2 KNZ73006.1 - 9e-10 38.1 0.8 2.3e-09 36.8 0.6 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KNZ73006.1 - 0.00022 20.9 2.8 0.58 9.9 0.0 4.4 4 2 0 4 4 4 2 Leucine rich repeat Colicin_M PF14859.1 KNZ73006.1 - 0.17 10.7 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Colicin M p450 PF00067.17 KNZ73007.1 - 5.5e-71 239.4 0.0 6.2e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PEP-utilisers_N PF05524.8 KNZ73008.1 - 0.11 12.3 0.2 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Gon7 PF08738.5 KNZ73008.1 - 0.11 12.4 0.1 0.14 12.1 0.1 1.3 1 1 0 1 1 1 0 Gon7 family Methyltransf_16 PF10294.4 KNZ73009.1 - 4.9e-13 48.8 0.0 8.3e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KNZ73009.1 - 1.7e-06 28.6 0.0 3.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ73009.1 - 7.8e-05 23.0 0.0 0.00026 21.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ73009.1 - 0.00034 20.2 0.0 0.0014 18.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ73009.1 - 0.00038 20.1 0.0 0.00077 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ73009.1 - 0.0025 17.8 0.1 0.0088 16.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ73009.1 - 0.024 15.1 0.0 0.063 13.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain RVP PF00077.15 KNZ73011.1 - 0.044 13.7 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF3363 PF11843.3 KNZ73011.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) zf-CCHC PF00098.18 KNZ73013.1 - 0.014 15.3 0.7 0.036 14.0 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 KNZ73013.1 - 0.05 13.0 0.3 0.12 11.8 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.1 KNZ73014.1 - 0.1 13.1 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.1 KNZ73014.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HSA PF07529.8 KNZ73016.1 - 0.034 13.9 0.4 0.069 12.9 0.3 1.5 1 0 0 1 1 1 0 HSA PHY PF00360.15 KNZ73017.1 - 2.5e-26 91.9 0.0 4.5e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 KNZ73017.1 - 1.7e-19 69.5 0.1 3.1e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KNZ73017.1 - 8.8e-17 61.1 0.3 2.2e-16 59.8 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Abhydrolase_5 PF12695.2 KNZ73017.1 - 2e-16 60.0 0.0 5.1e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family GAF PF01590.21 KNZ73017.1 - 5e-13 49.4 0.0 2.5e-12 47.1 0.0 2.3 2 0 0 2 2 2 1 GAF domain Abhydrolase_6 PF12697.2 KNZ73017.1 - 1.2e-11 44.9 2.4 8.4e-10 38.9 1.7 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAS_2 PF08446.6 KNZ73017.1 - 3.7e-09 37.0 0.0 1.8e-08 34.8 0.0 2.3 1 0 0 1 1 1 1 PAS fold Abhydrolase_1 PF00561.15 KNZ73017.1 - 7e-08 32.3 0.1 9.3e-05 22.0 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold HisKA PF00512.20 KNZ73017.1 - 1e-05 25.4 0.2 3.1e-05 23.8 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain OKR_DC_1_N PF03709.10 KNZ73017.1 - 0.027 14.5 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain HATPase_c_3 PF13589.1 KNZ73017.1 - 0.062 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lipase_3 PF01764.20 KNZ73017.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.13 KNZ73017.1 - 0.12 11.6 0.0 1.2 8.3 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF3089 PF11288.3 KNZ73017.1 - 0.13 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) AXE1 PF05448.7 KNZ73017.1 - 0.24 9.8 0.0 0.48 8.8 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) HCO3_cotransp PF00955.16 KNZ73018.1 - 1.1e-62 212.4 10.2 1.1e-31 110.0 0.3 2.0 1 1 1 2 2 2 2 HCO3- transporter family His_Phos_2 PF00328.17 KNZ73019.1 - 6.7e-08 32.2 0.1 2.1e-06 27.2 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 KNZ73019.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) DUF1762 PF08574.5 KNZ73020.1 - 9.3e-09 35.5 9.5 9.3e-09 35.5 6.6 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1762) cobW PF02492.14 KNZ73021.1 - 3.2e-26 91.8 0.0 3.9e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 KNZ73021.1 - 0.0015 18.5 0.0 0.0049 16.8 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase TIP49 PF06068.8 KNZ73021.1 - 0.0075 15.0 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 KNZ73021.1 - 0.022 14.1 0.1 0.078 12.3 0.0 1.7 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KNZ73021.1 - 0.027 14.7 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter UPF0079 PF02367.12 KNZ73021.1 - 0.062 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CbiA PF01656.18 KNZ73021.1 - 0.064 12.6 0.2 0.095 12.1 0.2 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.9 KNZ73021.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 KNZ73021.1 - 0.076 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_26 PF13500.1 KNZ73021.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KNZ73021.1 - 0.1 12.9 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KNZ73021.1 - 0.11 12.8 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KNZ73021.1 - 0.11 13.3 0.1 0.2 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 KNZ73021.1 - 0.12 11.3 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain IstB_IS21 PF01695.12 KNZ73021.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 KNZ73021.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 KNZ73021.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 KNZ73021.1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin HVSL PF09749.4 KNZ73022.1 - 8.8e-40 136.2 2.7 2.4e-39 134.7 1.9 1.7 1 1 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 KNZ73022.1 - 3.2e-05 23.6 2.1 3.9e-05 23.4 0.6 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily RNase_H PF00075.19 KNZ73023.1 - 8.4e-09 35.8 0.1 1.3e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 RNase H UAA PF08449.6 KNZ73024.1 - 5.4e-71 239.0 17.7 6.4e-71 238.7 12.2 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 KNZ73024.1 - 2.3e-07 30.1 0.8 3.8e-07 29.4 0.5 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 KNZ73024.1 - 4.7e-05 23.4 23.0 0.0078 16.2 6.2 2.6 2 1 0 2 2 2 2 EamA-like transporter family DUF914 PF06027.7 KNZ73024.1 - 0.0054 15.6 0.4 0.0054 15.6 0.3 2.0 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 KNZ73024.1 - 0.01 16.0 6.7 0.01 16.0 4.7 2.8 3 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF1392 PF07154.6 KNZ73024.1 - 0.033 14.0 0.4 0.77 9.6 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1392) Orbi_NS3 PF01616.11 KNZ73024.1 - 0.19 10.6 3.0 0.16 10.9 0.7 1.7 2 0 0 2 2 2 0 Orbivirus NS3 Mur_ligase_M PF08245.7 KNZ73025.1 - 1.7e-07 31.5 0.0 1.5e-06 28.3 0.0 2.4 1 1 0 1 1 1 1 Mur ligase middle domain Methyltransf_31 PF13847.1 KNZ73026.1 - 3.5e-21 75.3 0.0 5.5e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ73026.1 - 1.6e-20 73.3 0.0 3.1e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ73026.1 - 1.3e-18 67.2 0.0 2.1e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ73026.1 - 3.6e-16 59.7 0.0 8.2e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ73026.1 - 1.8e-14 54.0 0.0 3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNZ73026.1 - 4.5e-12 45.5 0.0 1.5e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KNZ73026.1 - 1.4e-10 41.4 0.0 1.9e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KNZ73026.1 - 3.4e-10 39.5 0.0 5.6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 KNZ73026.1 - 5.5e-07 28.5 0.0 7.6e-07 28.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 KNZ73026.1 - 2.4e-06 27.5 0.0 6.6e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KNZ73026.1 - 7.9e-06 25.5 0.1 1.6e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 KNZ73026.1 - 5e-05 22.5 0.0 7.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KNZ73026.1 - 5.8e-05 22.7 0.0 9.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KNZ73026.1 - 7e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MetW PF07021.7 KNZ73026.1 - 0.0003 20.2 0.0 0.00043 19.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 KNZ73026.1 - 0.0011 18.1 0.0 0.0016 17.5 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.7 KNZ73026.1 - 0.0028 16.5 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase ADH_zinc_N PF00107.21 KNZ73026.1 - 0.031 13.8 0.0 0.19 11.2 0.0 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_4 PF02390.12 KNZ73026.1 - 0.053 12.5 0.0 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase RrnaAD PF00398.15 KNZ73026.1 - 0.054 12.5 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase zf-Tim10_DDP PF02953.10 KNZ73026.1 - 0.13 11.5 0.1 0.46 9.7 0.0 1.8 2 0 0 2 2 2 0 Tim10/DDP family zinc finger RRM_1 PF00076.17 KNZ73027.1 - 1.4e-06 27.8 0.0 2.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ73027.1 - 3.7e-06 26.8 0.0 8.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ73027.1 - 0.0019 17.9 0.0 0.0042 16.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KNZ73027.1 - 0.0047 16.7 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 KNZ73027.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif LRR_4 PF12799.2 KNZ73029.1 - 1e-26 92.0 30.3 1.2e-07 31.1 0.2 8.6 5 3 5 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNZ73029.1 - 1.1e-19 69.8 24.8 0.00015 21.4 1.0 7.0 2 1 6 8 8 8 8 Leucine rich repeat LRR_1 PF00560.28 KNZ73029.1 - 1.4e-09 36.6 32.5 1.4 9.2 0.0 11.9 10 3 0 10 10 10 4 Leucine Rich Repeat LRR_7 PF13504.1 KNZ73029.1 - 2.1e-08 33.0 31.9 2.9 8.4 0.0 12.7 14 0 0 14 14 14 4 Leucine rich repeat LRR_9 PF14580.1 KNZ73029.1 - 2.7e-06 27.0 7.7 0.37 10.3 0.0 4.1 2 1 1 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.1 KNZ73029.1 - 0.14 12.2 31.7 9 6.7 0.2 9.9 8 3 3 11 11 11 0 Leucine Rich repeat SpoIIIAH PF12685.2 KNZ73031.1 - 0.016 14.7 5.6 0.023 14.1 3.9 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF1510 PF07423.6 KNZ73031.1 - 0.038 13.3 10.4 0.046 13.0 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAPS PF04499.10 KNZ73031.1 - 0.24 10.0 4.5 0.23 10.0 3.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mem_trans PF03547.13 KNZ73031.1 - 0.59 8.3 2.2 0.7 8.1 1.5 1.1 1 0 0 1 1 1 0 Membrane transport protein Hid1 PF12722.2 KNZ73031.1 - 1.5 6.4 10.0 1.6 6.2 6.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF605 PF04652.11 KNZ73031.1 - 4.3 6.6 16.7 5.1 6.3 11.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF2413 PF10310.4 KNZ73031.1 - 6.8 5.3 14.8 8.5 5.0 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Mucin PF01456.12 KNZ73031.1 - 7.7 6.2 14.0 11 5.7 9.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF202 PF02656.10 KNZ73032.1 - 1.6e-18 66.6 2.4 1.6e-18 66.6 1.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PMP22_Claudin PF00822.15 KNZ73032.1 - 0.3 10.7 2.9 0.51 9.9 2.0 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF3040 PF11239.3 KNZ73032.1 - 6.1 6.9 7.4 20 5.2 4.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) SET PF00856.23 KNZ73033.1 - 4.4e-10 40.0 0.0 7.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 SET domain NIPSNAP PF07978.8 KNZ73033.1 - 0.00052 19.9 0.9 0.0016 18.4 0.4 2.0 2 0 0 2 2 2 1 NIPSNAP FAD_binding_1 PF00667.15 KNZ73034.1 - 1.1e-52 178.6 0.0 8e-52 175.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KNZ73034.1 - 9e-32 110.0 0.6 1.7e-31 109.1 0.4 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KNZ73034.1 - 3.9e-21 75.6 0.0 2.6e-20 73.0 0.0 2.3 2 1 1 3 3 3 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KNZ73034.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain She9_MDM33 PF05546.6 KNZ73035.1 - 3.5e-72 242.3 10.8 5.5e-72 241.6 7.5 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family KAP_NTPase PF07693.9 KNZ73035.1 - 0.085 11.8 1.5 0.095 11.6 0.5 1.4 1 1 0 1 1 1 0 KAP family P-loop domain CDP-OH_P_tran_2 PF08009.6 KNZ73035.1 - 0.37 10.5 1.3 0.65 9.7 0.9 1.3 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 Methyltransf_23 PF13489.1 KNZ73036.1 - 0.0049 16.6 0.0 0.0093 15.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain HIT PF01230.18 KNZ73037.1 - 1.8e-19 70.0 0.1 3.3e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KNZ73037.1 - 6.2e-13 48.9 0.1 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KNZ73037.1 - 8.7e-05 22.1 0.1 0.00014 21.4 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CBFD_NFYB_HMF PF00808.18 KNZ73038.1 - 2.4e-15 56.3 2.1 2.4e-15 56.3 1.5 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KNZ73038.1 - 4.8e-07 29.8 1.3 7.2e-07 29.2 0.6 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KNZ73038.1 - 0.068 12.9 0.1 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated CPSF_A PF03178.10 KNZ73039.1 - 1.2e-48 165.8 0.0 5.6e-48 163.6 0.0 2.2 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 KNZ73039.1 - 1.4e-45 155.4 0.0 3.9e-45 153.9 0.0 1.7 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Na_Ca_ex PF01699.19 KNZ73040.1 - 1.1e-26 93.1 23.1 3.2e-16 59.2 5.4 3.3 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF997 PF06196.7 KNZ73040.1 - 4.8 6.7 10.6 3 7.4 0.4 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF997) Glyco_hydro_43 PF04616.9 KNZ73042.1 - 1.2e-34 119.6 3.1 1.6e-34 119.3 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ADH_N PF08240.7 KNZ73043.1 - 1.4e-25 89.2 0.5 2.6e-25 88.2 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KNZ73043.1 - 1.1e-09 37.8 0.1 2.7e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FliW PF02623.10 KNZ73043.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 FliW protein Mon1 PF03164.9 KNZ73044.1 - 7.2e-81 271.8 0.0 4.4e-58 196.8 0.1 2.1 2 0 0 2 2 2 2 Trafficking protein Mon1 IGR PF09597.5 KNZ73045.1 - 0.025 14.4 0.3 0.039 13.8 0.2 1.3 1 0 0 1 1 1 0 IGR protein motif CRAL_TRIO PF00650.15 KNZ73046.1 - 2.8e-25 88.6 0.0 4.3e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KNZ73046.1 - 9.1e-12 44.9 0.2 2.6e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Glyco_hydro_71 PF03659.9 KNZ73048.1 - 9.5e-91 304.1 6.8 1.7e-51 174.9 0.3 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 71 Glyco_tran_WbsX PF14307.1 KNZ73048.1 - 0.052 12.7 0.0 0.19 10.8 0.0 1.8 1 1 0 1 1 1 0 Glycosyltransferase WbsX vATP-synt_AC39 PF01992.11 KNZ73049.1 - 8e-103 344.1 0.0 9e-103 343.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit MFS_1 PF07690.11 KNZ73050.1 - 3.1e-30 105.0 28.7 3.1e-30 105.0 19.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily SQS_PSY PF00494.14 KNZ73052.1 - 7.5e-47 159.8 0.0 9.3e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Syndecan PF01034.15 KNZ73052.1 - 0.013 15.1 0.2 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Ribosomal_L28 PF00830.14 KNZ73053.1 - 2.2e-22 78.6 0.7 4.1e-22 77.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal L28 family HYLS1_C PF15311.1 KNZ73053.1 - 0.22 11.7 1.9 0.81 9.9 0.1 2.3 2 1 0 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus Complex1_LYR PF05347.10 KNZ73054.1 - 9.9e-08 31.6 0.1 1.3e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KNZ73054.1 - 4.6e-07 29.9 0.2 5.7e-07 29.6 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like MRP-L47 PF06984.8 KNZ73055.1 - 3.5e-23 81.3 2.9 1.1e-22 79.7 2.0 1.9 1 1 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.18 KNZ73055.1 - 0.014 15.0 0.3 0.014 15.0 0.2 2.6 3 0 0 3 3 3 0 Ribosomal L29 protein SecD-TM1 PF13721.1 KNZ73055.1 - 0.12 12.6 0.6 0.33 11.2 0.1 1.8 1 1 1 2 2 2 0 SecD export protein N-terminal TM region alpha-hel2 PF14456.1 KNZ73055.1 - 0.23 10.2 4.0 0.35 9.6 2.8 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 DUF940 PF06082.6 KNZ73055.1 - 0.97 7.9 4.4 1.1 7.7 3.0 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) AAA_23 PF13476.1 KNZ73056.1 - 1.5e-25 90.6 0.0 1.5e-25 90.6 0.0 8.1 1 1 2 4 4 2 1 AAA domain SbcCD_C PF13558.1 KNZ73056.1 - 6.3e-11 42.0 0.1 2.7e-10 40.0 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KNZ73056.1 - 8.8e-11 42.2 0.1 9.1e-07 29.1 0.2 4.5 5 2 0 5 5 5 2 AAA domain SMC_N PF02463.14 KNZ73056.1 - 1.3e-09 37.6 0.1 1.3e-09 37.6 0.1 4.7 4 2 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KNZ73056.1 - 3.7e-07 29.5 0.0 3.7e-07 29.5 0.0 6.1 3 1 2 5 5 2 1 AAA ATPase domain AAA_13 PF13166.1 KNZ73056.1 - 6.7e-07 28.1 0.2 3.5e-05 22.5 0.0 7.7 4 2 4 8 8 8 4 AAA domain AAA_29 PF13555.1 KNZ73056.1 - 0.00072 19.0 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KNZ73056.1 - 0.0031 17.7 0.1 0.0031 17.7 0.0 7.5 3 2 0 3 3 1 1 ABC transporter AAA_19 PF13245.1 KNZ73056.1 - 0.041 13.6 0.3 0.52 10.1 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain Cyc-maltodext_C PF10438.4 KNZ73056.1 - 0.12 12.3 2.6 0.17 11.9 0.2 2.6 2 0 0 2 2 1 0 Cyclo-malto-dextrinase C-terminal domain Filament PF00038.16 KNZ73056.1 - 0.4 10.0 132.2 0.031 13.7 22.6 5.5 1 1 4 5 5 5 0 Intermediate filament protein SET PF00856.23 KNZ73057.1 - 3.4e-09 37.2 0.1 5.9e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.13 KNZ73057.1 - 2.6e-07 30.4 14.9 2.6e-07 30.4 10.3 1.7 2 0 0 2 2 2 1 MYND finger DER1 PF04511.10 KNZ73058.1 - 1.2e-47 161.9 5.3 1.4e-47 161.8 3.7 1.0 1 0 0 1 1 1 1 Der1-like family NDK PF00334.14 KNZ73059.1 - 3.2e-17 62.5 0.0 6.7e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Mmp37 PF09139.6 KNZ73060.1 - 9.9e-88 294.3 0.0 1.3e-87 293.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 ATP-synt_C PF00137.16 KNZ73062.1 - 6.3e-16 58.0 16.6 7.5e-16 57.7 6.7 2.3 2 0 0 2 2 2 2 ATP synthase subunit C DUF2484 PF10658.4 KNZ73062.1 - 7.7 6.7 8.5 17 5.6 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2484) EHN PF06441.7 KNZ73063.1 - 1.8e-32 111.5 0.6 1.2e-31 108.9 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KNZ73063.1 - 1.1e-12 48.3 0.6 3e-12 46.9 0.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ73063.1 - 0.00014 21.4 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Dynamin_N PF00350.18 KNZ73064.1 - 7.5e-19 68.1 0.1 2.1e-18 66.7 0.1 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KNZ73064.1 - 7.7e-12 45.1 0.1 5.3e-11 42.4 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KNZ73064.1 - 3.1e-10 39.7 0.6 1.1e-09 38.0 0.4 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KNZ73064.1 - 6.6e-05 23.3 0.3 0.0061 17.0 0.2 2.8 1 1 0 1 1 1 1 Miro-like protein cobW PF02492.14 KNZ73064.1 - 0.00095 18.6 0.6 0.01 15.2 0.4 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.8 KNZ73064.1 - 0.0017 17.2 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 KNZ73064.1 - 0.0066 15.9 0.0 0.027 13.9 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Septin PF00735.13 KNZ73064.1 - 0.018 14.0 0.0 0.039 12.9 0.0 1.7 1 0 0 1 1 1 0 Septin FeoB_N PF02421.13 KNZ73064.1 - 0.073 12.3 0.2 7.3 5.8 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF258 PF03193.11 KNZ73064.1 - 0.1 11.7 0.1 0.64 9.1 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SAM_2 PF07647.12 KNZ73065.1 - 4.7e-11 42.3 0.0 1.9e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KNZ73065.1 - 9.2e-06 25.7 0.0 2.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.1 KNZ73065.1 - 0.11 12.5 0.1 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) adh_short PF00106.20 KNZ73066.1 - 4.8e-26 91.6 0.9 6.3e-26 91.2 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ73066.1 - 1.4e-09 38.0 0.0 2e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ73066.1 - 4.4e-07 29.7 0.4 7.2e-07 29.0 0.3 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KNZ73066.1 - 0.084 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3012 PF11216.3 KNZ73066.1 - 0.13 11.9 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) NifU PF01106.12 KNZ73067.1 - 0.00051 19.7 0.2 1.8 8.3 0.0 3.3 3 0 0 3 3 3 2 NifU-like domain ADH_zinc_N PF00107.21 KNZ73068.1 - 7.3e-25 87.0 0.0 1.1e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KNZ73068.1 - 5.1e-15 56.4 0.0 1.3e-14 55.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ73068.1 - 5.8e-08 32.4 0.0 7.5e-07 28.8 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_5 PF12695.2 KNZ73069.1 - 1.9e-07 30.9 0.0 2.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ73069.1 - 6.9e-07 29.3 0.1 9e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ73069.1 - 6.3e-06 25.5 0.2 1.6e-05 24.2 0.1 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF915 PF06028.6 KNZ73069.1 - 0.0033 16.5 0.0 0.016 14.3 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF1749 PF08538.5 KNZ73069.1 - 0.14 10.9 0.0 0.27 10.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Ribosomal_L1 PF00687.16 KNZ73070.1 - 4.7e-56 189.5 0.9 7.4e-56 188.9 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family EBP50_C-term PF09007.6 KNZ73070.1 - 0.32 10.8 1.8 0.54 10.1 0.5 1.9 2 0 0 2 2 2 0 EBP50, C-terminal Macoilin PF09726.4 KNZ73070.1 - 0.71 8.0 4.6 0.85 7.8 3.2 1.1 1 0 0 1 1 1 0 Transmembrane protein FoP_duplication PF13865.1 KNZ73071.1 - 0.075 13.4 2.3 0.28 11.6 1.6 2.0 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Peptidase_M64 PF09471.5 KNZ73072.1 - 6.9e-26 91.4 0.0 1.1e-25 90.8 0.0 1.2 1 0 0 1 1 1 1 IgA Peptidase M64 MIP PF00230.15 KNZ73074.1 - 4.7e-52 176.7 8.5 5.5e-52 176.4 5.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein EamA PF00892.15 KNZ73074.1 - 0.057 13.4 7.6 0.09 12.8 1.2 2.6 2 0 0 2 2 2 0 EamA-like transporter family Oxidored_q3 PF00499.15 KNZ73074.1 - 1.1 8.9 7.3 0.19 11.5 1.2 2.4 1 1 2 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 NTR2 PF15458.1 KNZ73075.1 - 5.5e-63 212.5 5.4 5.5e-63 212.5 3.8 2.2 3 0 0 3 3 3 1 Nineteen complex-related protein 2 Rad60-SLD PF11976.3 KNZ73076.1 - 4.1e-11 42.3 0.2 0.00043 19.9 0.2 3.5 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KNZ73076.1 - 0.072 12.4 0.0 5.1 6.5 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin family mRNA_triPase PF02940.10 KNZ73077.1 - 3.6e-51 173.9 0.0 4.3e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Porin_3 PF01459.17 KNZ73078.1 - 2.9e-63 213.7 2.8 3.4e-63 213.5 2.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Pkinase PF00069.20 KNZ73079.1 - 2e-43 148.4 0.0 3.2e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73079.1 - 1.8e-23 82.9 0.0 3.1e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ73079.1 - 4.8e-06 25.7 0.0 8.8e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ73079.1 - 0.00027 20.7 0.0 0.00075 19.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ73079.1 - 0.005 16.4 0.6 0.34 10.4 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 KNZ73079.1 - 0.12 11.7 0.0 0.31 10.3 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 KNZ73079.1 - 0.55 8.9 0.1 0.81 8.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KNZ73080.1 - 4e-73 245.7 0.0 6.4e-73 245.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73080.1 - 6.5e-52 176.1 0.0 1.1e-51 175.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ73080.1 - 0.0003 19.8 0.0 0.0015 17.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KNZ73080.1 - 0.24 10.4 0.0 0.61 9.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_1 PF00078.22 KNZ73081.1 - 0.00033 20.0 0.0 0.0006 19.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 KNZ73082.1 - 1.7e-09 38.1 0.0 2.8e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 RNase H OMP_b-brl PF13505.1 KNZ73083.1 - 0.014 15.3 1.2 0.022 14.6 0.8 1.3 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain WD40 PF00400.27 KNZ73084.1 - 6.1e-17 60.7 5.7 1.1e-06 28.3 0.0 6.8 8 1 0 8 8 8 4 WD domain, G-beta repeat Homeobox PF00046.24 KNZ73085.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Homeobox domain Mob1_phocein PF03637.12 KNZ73087.1 - 3e-64 215.9 1.2 3.8e-64 215.5 0.8 1.0 1 0 0 1 1 1 1 Mob1/phocein family RhoGEF PF00621.15 KNZ73088.1 - 2.1e-09 37.5 0.0 3.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain Mannosyl_trans2 PF04188.8 KNZ73090.1 - 2.2e-31 109.2 9.4 4.9e-24 85.0 5.3 2.1 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V)) Rhodanese PF00581.15 KNZ73091.1 - 1e-07 32.3 0.0 2.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain WD40 PF00400.27 KNZ73091.1 - 0.015 15.1 0.1 0.86 9.5 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat PH PF00169.24 KNZ73092.1 - 0.024 14.8 0.1 0.059 13.5 0.1 1.7 1 0 0 1 1 1 0 PH domain SSrecog PF03531.9 KNZ73093.1 - 1.4e-76 256.7 0.1 2.2e-76 256.1 0.0 1.3 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KNZ73093.1 - 1e-23 83.0 0.1 1.6e-21 76.0 0.0 2.7 2 0 0 2 2 2 2 Histone chaperone Rttp106-like DUF3966 PF13110.1 KNZ73093.1 - 0.13 12.0 3.7 0.097 12.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3966) CH PF00307.26 KNZ73094.1 - 6.5e-38 129.0 0.1 2.1e-23 82.4 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KNZ73094.1 - 4.2e-19 68.2 0.1 2.3e-18 65.8 0.0 2.4 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KNZ73094.1 - 2.5e-11 43.0 0.1 9.2e-09 34.8 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain Baculo_PEP_C PF04513.7 KNZ73094.1 - 2.8e-05 23.9 1.5 0.00012 21.9 1.0 2.0 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.16 KNZ73094.1 - 9.2e-05 22.6 2.0 0.073 13.3 0.9 2.8 2 0 0 2 2 2 2 Spectrin repeat EF-hand_6 PF13405.1 KNZ73094.1 - 0.00018 21.1 0.0 0.0043 16.8 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain Seryl_tRNA_N PF02403.17 KNZ73094.1 - 0.0024 17.8 0.8 0.0055 16.6 0.5 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain EF-hand_7 PF13499.1 KNZ73094.1 - 0.0041 17.2 0.4 0.083 13.0 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair DUF3153 PF11353.3 KNZ73094.1 - 0.0043 16.5 1.6 0.0089 15.4 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3153) Syntaxin PF00804.20 KNZ73094.1 - 0.0058 16.7 1.8 0.02 15.0 0.5 2.4 2 0 0 2 2 2 1 Syntaxin DUF4404 PF14357.1 KNZ73094.1 - 0.01 16.2 0.7 0.058 13.8 0.5 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) EF-hand_1 PF00036.27 KNZ73094.1 - 0.012 14.8 0.0 0.044 13.1 0.0 2.1 1 0 0 1 1 1 0 EF hand DUF2450 PF10475.4 KNZ73094.1 - 0.02 13.8 0.1 0.041 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Spc7 PF08317.6 KNZ73094.1 - 0.027 13.1 2.7 0.043 12.4 1.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.3 KNZ73094.1 - 0.056 10.7 6.2 0.0094 13.3 1.9 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) SF-assemblin PF06705.6 KNZ73094.1 - 0.064 12.4 5.4 0.016 14.3 1.6 1.5 2 0 0 2 2 2 0 SF-assemblin/beta giardin Fib_alpha PF08702.5 KNZ73094.1 - 0.072 13.2 2.5 1.1 9.3 0.3 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family WASH_WAHD PF11945.3 KNZ73094.1 - 0.075 12.3 0.4 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 WAHD domain of WASH complex NPV_P10 PF05531.7 KNZ73094.1 - 0.079 13.2 0.6 0.62 10.3 0.5 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF3826 PF12875.2 KNZ73094.1 - 0.11 12.2 1.6 0.61 9.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3826) Endonuc-dimeris PF09124.5 KNZ73094.1 - 0.11 12.1 0.0 0.36 10.4 0.0 1.9 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation Apolipoprotein PF01442.13 KNZ73094.1 - 0.18 11.2 4.3 0.53 9.7 2.2 2.0 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Cofilin_ADF PF00241.15 KNZ73095.1 - 1.1e-42 144.9 0.5 1.2e-42 144.7 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Asp_protease_2 PF13650.1 KNZ73096.1 - 0.0016 18.9 0.0 0.0025 18.3 0.0 1.3 1 1 0 1 1 1 1 Aspartyl protease DUF3605 PF12239.3 KNZ73098.1 - 2.6e-27 95.5 0.4 1.4e-11 44.4 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF3605) Cas_Csa5 PF09702.5 KNZ73099.1 - 0.13 12.3 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) LRR_6 PF13516.1 KNZ73100.1 - 4.5e-11 41.6 16.4 2.8 8.2 0.0 7.8 7 1 1 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.28 KNZ73100.1 - 6.5e-08 31.5 5.9 2.3 8.5 0.1 7.4 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_4 PF12799.2 KNZ73100.1 - 2.7e-06 26.8 20.3 0.5 10.0 0.0 6.3 2 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNZ73100.1 - 0.0032 17.1 12.8 24 4.8 0.0 5.4 4 2 0 4 4 4 2 Leucine rich repeat TPR_MLP1_2 PF07926.7 KNZ73101.1 - 6.9e-20 71.1 18.4 6.9e-20 71.1 12.8 17.2 4 3 10 14 14 14 6 TPR/MLP1/MLP2-like protein APG6 PF04111.7 KNZ73101.1 - 0.0009 18.3 15.2 0.0009 18.3 10.5 14.3 3 2 13 16 16 16 2 Autophagy protein Apg6 Hemerythrin PF01814.18 KNZ73103.1 - 2.4e-14 53.6 0.4 3.8e-14 53.0 0.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain AceK PF06315.6 KNZ73103.1 - 0.0062 14.8 0.2 0.0075 14.5 0.1 1.1 1 0 0 1 1 1 1 Isocitrate dehydrogenase kinase/phosphatase (AceK) Chromo PF00385.19 KNZ73104.1 - 2.1e-07 30.4 0.7 3.3e-07 29.8 0.5 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.20 KNZ73105.1 - 9.7e-39 133.0 0.0 9.4e-21 74.1 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73105.1 - 5e-13 48.7 0.2 0.00022 20.3 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KNZ73105.1 - 0.031 13.0 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Lipase_GDSL_2 PF13472.1 KNZ73106.1 - 5.9e-08 33.0 0.0 7.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KNZ73106.1 - 3.3e-05 23.8 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Aldo_ket_red PF00248.16 KNZ73107.1 - 2e-67 226.9 0.0 2.5e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.14 KNZ73108.1 - 1.5e-54 185.1 0.0 2e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ73108.1 - 1.9e-38 131.9 0.0 3e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KNZ73108.1 - 1.2e-05 24.3 0.3 0.00024 20.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KNZ73108.1 - 2.7e-05 24.1 0.0 5.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KNZ73108.1 - 4.8e-05 22.3 0.0 0.011 14.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KNZ73108.1 - 0.00063 18.7 0.0 0.00093 18.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KNZ73108.1 - 0.008 16.0 0.0 0.03 14.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KNZ73108.1 - 0.057 11.8 0.0 0.19 10.1 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 KNZ73108.1 - 0.063 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 KNZ73108.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain AMP-binding PF00501.23 KNZ73109.1 - 4.4e-74 249.3 0.0 5.7e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Glyco_hydro_61 PF03443.9 KNZ73110.1 - 1.2e-37 129.8 0.0 1.5e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 FlgD_ig PF13860.1 KNZ73110.1 - 0.079 12.7 0.0 0.33 10.7 0.0 1.9 1 1 0 1 1 1 0 FlgD Ig-like domain Yae1_N PF09811.4 KNZ73111.1 - 0.12 11.8 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Abhydrolase_6 PF12697.2 KNZ73113.1 - 2.6e-19 69.9 0.0 4.1e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ73113.1 - 4.7e-12 45.9 0.0 1.1e-09 38.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ73113.1 - 0.00038 20.2 0.0 0.0011 18.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KNZ73113.1 - 0.071 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.8 KNZ73113.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Erythro-docking PF09277.6 KNZ73113.1 - 0.14 11.8 0.3 6.6 6.5 0.1 2.3 2 0 0 2 2 2 0 Erythronolide synthase, docking Asp_protease_2 PF13650.1 KNZ73114.1 - 0.0052 17.2 0.0 0.012 16.1 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 KNZ73114.1 - 0.0085 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Aldo_ket_red PF00248.16 KNZ73116.1 - 1.8e-69 233.7 0.0 2.2e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family H_kinase_N PF12282.3 KNZ73118.1 - 0.0059 16.2 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Signal transduction histidine kinase FlaC_arch PF05377.6 KNZ73118.1 - 0.046 13.6 1.8 3.1 7.7 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.16 KNZ73118.1 - 0.046 13.6 5.1 0.39 10.6 0.2 2.8 3 0 0 3 3 3 0 bZIP transcription factor Prefoldin_2 PF01920.15 KNZ73118.1 - 0.45 10.2 7.5 3.2 7.5 0.5 3.0 3 0 0 3 3 3 0 Prefoldin subunit bZIP_2 PF07716.10 KNZ73118.1 - 1.3 8.9 7.8 5.4 6.9 1.0 2.8 2 0 0 2 2 2 0 Basic region leucine zipper Tropomyosin_1 PF12718.2 KNZ73118.1 - 6.9 6.5 10.6 1.8 8.3 0.2 3.0 3 0 0 3 3 3 0 Tropomyosin like Pkinase PF00069.20 KNZ73119.1 - 0.0024 17.0 0.3 0.03 13.4 0.1 2.6 3 0 0 3 3 3 1 Protein kinase domain Ank_2 PF12796.2 KNZ73127.1 - 3.9e-17 62.3 1.8 6.2e-17 61.7 0.9 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ73127.1 - 3.8e-14 51.6 4.3 1.2e-05 24.8 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KNZ73127.1 - 1.3e-09 37.3 1.3 0.0033 17.5 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KNZ73127.1 - 2.1e-09 37.6 0.2 0.00026 21.4 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KNZ73127.1 - 1.3e-08 34.7 3.0 3.7e-05 23.8 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) AfaD PF05775.7 KNZ73127.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein CRISPR_assoc PF08798.6 KNZ73129.1 - 0.047 13.4 0.1 0.056 13.2 0.1 1.0 1 0 0 1 1 1 0 CRISPR associated protein UPF0147 PF03685.8 KNZ73130.1 - 0.027 14.3 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) LELP1 PF15042.1 KNZ73133.1 - 4 7.6 10.6 1.1e+02 3.0 7.3 2.5 1 1 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Asp_protease_2 PF13650.1 KNZ73134.1 - 0.11 13.0 0.0 3.2 8.3 0.0 2.6 2 1 0 2 2 2 0 Aspartyl protease TMEM247 PF15444.1 KNZ73135.1 - 0.023 14.5 0.1 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 Plasmodium_Vir PF05795.6 KNZ73135.1 - 0.16 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF443 PF04276.7 KNZ73135.1 - 0.25 10.7 4.5 0.065 12.6 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF443) RNase_H PF00075.19 KNZ73136.1 - 0.00033 21.0 1.1 0.00053 20.3 0.8 1.4 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.1 KNZ73136.1 - 0.027 14.2 0.6 0.45 10.3 0.2 2.1 1 1 1 2 2 2 0 Reverse transcriptase-like NMD3 PF04981.8 KNZ73136.1 - 0.032 13.3 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 NMD3 family DUF1283 PF06932.6 KNZ73136.1 - 0.036 14.0 0.1 0.054 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) rve PF00665.21 KNZ73140.1 - 1.8e-15 57.0 0.0 2.5e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KNZ73140.1 - 0.0035 16.8 0.0 0.0085 15.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain TUG-UBL1 PF11470.3 KNZ73140.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG CN_hydrolase PF00795.17 KNZ73145.1 - 6.2e-09 35.4 0.0 1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF4632 PF15451.1 KNZ73145.1 - 0.024 14.5 2.5 0.061 13.2 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Helicase_C PF00271.26 KNZ73146.1 - 2.4e-17 62.5 0.1 7.2e-15 54.6 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.24 KNZ73146.1 - 3.1e-09 36.5 0.0 6.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Aldolase_II PF00596.16 KNZ73147.1 - 2.3e-34 118.6 0.0 2.7e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Melibiase PF02065.13 KNZ73148.1 - 4e-14 52.1 0.0 5.2e-12 45.1 0.0 2.8 3 0 0 3 3 3 2 Melibiase Nepo_coat PF03391.10 KNZ73148.1 - 1.4 8.1 5.8 0.24 10.6 1.3 1.7 2 0 0 2 2 2 0 Nepovirus coat protein, central domain PAS_3 PF08447.6 KNZ73149.1 - 2.1e-07 30.9 0.0 5.4e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 KNZ73149.1 - 0.00031 20.5 0.0 0.0063 16.2 0.0 2.5 3 0 0 3 3 3 1 PAS fold PAS_11 PF14598.1 KNZ73149.1 - 0.036 14.0 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_9 PF13426.1 KNZ73149.1 - 0.088 13.1 0.0 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 PAS domain GCD14 PF08704.5 KNZ73150.1 - 5.6e-85 284.7 2.3 5.8e-83 278.1 1.6 2.8 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 KNZ73150.1 - 0.00038 20.4 0.0 0.00077 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KNZ73150.1 - 0.0005 19.6 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 KNZ73150.1 - 0.005 17.6 0.0 0.0097 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ73150.1 - 0.0074 16.8 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ73150.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain BHD_3 PF10405.4 KNZ73151.1 - 2.8e-27 94.2 0.2 5.9e-27 93.2 0.2 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 KNZ73151.1 - 1.2e-23 83.1 0.0 7e-23 80.6 0.0 2.3 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 KNZ73151.1 - 2.4e-21 74.9 0.0 8.3e-21 73.2 0.0 2.0 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KNZ73151.1 - 1.5e-12 47.6 0.8 4.4e-12 46.1 0.0 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KNZ73151.1 - 2.6e-08 34.0 0.0 1.1e-07 32.0 0.0 2.1 1 1 0 1 1 1 1 Transglutaminase-like superfamily Sdh_cyt PF01127.17 KNZ73152.1 - 0.025 14.4 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit zf-RVT PF13966.1 KNZ73152.1 - 0.14 12.4 2.2 0.16 12.2 1.5 1.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_3 PF13456.1 KNZ73153.1 - 0.016 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like MFS_1 PF07690.11 KNZ73155.1 - 1.5e-25 89.6 39.3 6.4e-15 54.7 6.0 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ73155.1 - 2.6e-24 85.6 18.4 1.7e-20 73.0 0.5 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter Ribonuc_L-PSP PF01042.16 KNZ73156.1 - 3.9e-06 26.6 0.2 0.0082 15.8 0.0 2.1 1 1 1 2 2 2 2 Endoribonuclease L-PSP BNR_2 PF13088.1 KNZ73157.1 - 0.0017 17.6 0.3 0.0073 15.6 0.2 2.1 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 KNZ73157.1 - 0.0089 15.7 1.5 0.088 12.6 0.3 3.3 2 0 0 2 2 2 1 BNR/Asp-box repeat APH PF01636.18 KNZ73159.1 - 2.2e-15 57.0 0.0 1.2e-14 54.6 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KNZ73159.1 - 2.9e-05 22.9 0.1 0.0026 16.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Kdo PF06293.9 KNZ73159.1 - 0.022 13.8 0.0 0.061 12.3 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Avl9 PF09794.4 KNZ73160.1 - 1.4e-123 412.1 0.0 1.8e-123 411.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 KNZ73160.1 - 1.4e-07 31.1 0.0 0.018 14.7 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 KNZ73160.1 - 1.8e-07 30.7 0.2 0.0016 17.7 0.1 2.6 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) DUF2235 PF09994.4 KNZ73162.1 - 5.9e-77 258.7 0.0 8e-77 258.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KNZ73162.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.6 KNZ73162.1 - 0.098 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Pkinase PF00069.20 KNZ73163.1 - 1.3e-62 211.2 0.0 1.6e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73163.1 - 3.5e-36 124.5 0.0 4.5e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ73163.1 - 0.00046 19.2 0.0 0.001 18.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KNZ73163.1 - 0.0024 16.7 0.0 0.0058 15.4 0.0 1.6 2 0 0 2 2 2 1 Seadornavirus VP7 RabGAP-TBC PF00566.13 KNZ73164.1 - 9.8e-33 113.4 0.0 1.4e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_2 PF07653.12 KNZ73164.1 - 0.00056 19.3 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KNZ73164.1 - 0.029 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 SH3 domain zf-MYND PF01753.13 KNZ73165.1 - 2.6e-10 40.0 4.9 7.2e-10 38.5 3.4 1.8 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KNZ73165.1 - 0.00042 20.1 2.1 0.0013 18.5 1.5 1.8 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YjeF_N PF03853.10 KNZ73166.1 - 2.6e-33 115.0 0.0 3.6e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FYRN PF05964.9 KNZ73168.1 - 4.4e-16 58.0 0.2 9.6e-16 56.9 0.1 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.9 KNZ73168.1 - 1.5e-15 56.7 0.0 3.3e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus PsbW PF07123.7 KNZ73168.1 - 0.026 14.5 0.3 0.12 12.4 0.2 2.1 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Abhydrolase_3 PF07859.8 KNZ73169.1 - 1e-18 67.7 0.7 2.4e-13 50.1 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ73169.1 - 1.1e-13 51.1 0.0 4e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ73169.1 - 3.9e-13 49.1 0.3 1.4e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KNZ73169.1 - 9.5e-09 35.4 3.6 2.1e-08 34.3 2.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KNZ73169.1 - 0.00014 21.3 0.8 0.002 17.6 0.0 2.6 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase LIP PF03583.9 KNZ73169.1 - 0.0037 16.5 0.1 0.018 14.2 0.0 1.9 2 0 0 2 2 2 1 Secretory lipase DLH PF01738.13 KNZ73169.1 - 0.033 13.4 1.6 5.2 6.2 0.0 2.6 3 0 0 3 3 3 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 KNZ73169.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein CsbD PF05532.7 KNZ73171.1 - 0.051 13.2 2.1 0.058 13.0 0.6 1.7 2 0 0 2 2 2 0 CsbD-like SIR2 PF02146.12 KNZ73172.1 - 7.6e-40 136.5 0.0 2.7e-35 121.7 0.0 2.3 1 1 1 2 2 2 2 Sir2 family p450 PF00067.17 KNZ73173.1 - 8.2e-74 248.7 0.0 1e-73 248.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UPF0147 PF03685.8 KNZ73174.1 - 0.021 14.6 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) p450 PF00067.17 KNZ73175.1 - 2.8e-72 243.7 0.0 3.4e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 KNZ73176.1 - 3.7e-33 112.2 1.2 1.5e-06 27.8 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 KNZ73176.1 - 0.00096 17.4 0.0 0.0025 16.0 0.0 1.7 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Gmad1 PF10647.4 KNZ73176.1 - 0.017 14.4 0.0 2.8 7.2 0.0 2.2 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 KNZ73176.1 - 0.023 14.1 0.3 0.055 12.9 0.2 1.9 1 1 0 1 1 1 0 PQQ-like domain Nucleoporin_N PF08801.6 KNZ73176.1 - 0.045 12.4 0.1 7.8 5.1 0.0 2.8 1 1 2 3 3 3 0 Nup133 N terminal like Antig_Caf1 PF09255.5 KNZ73177.1 - 0.012 15.5 1.2 0.69 9.8 0.3 2.2 2 0 0 2 2 2 0 Caf1 Capsule antigen BTB PF00651.26 KNZ73178.1 - 0.049 13.6 0.1 0.15 12.0 0.0 1.9 2 1 0 2 2 2 0 BTB/POZ domain Peptidase_S28 PF05577.7 KNZ73179.1 - 3.3e-55 187.4 0.0 6.3e-55 186.4 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Chromo PF00385.19 KNZ73180.1 - 2.4e-18 65.5 0.1 3e-18 65.2 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SF3a60_bindingd PF12108.3 KNZ73180.1 - 0.0011 18.4 0.1 0.0027 17.1 0.1 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain Mtf2_C PF14061.1 KNZ73180.1 - 0.07 13.0 0.2 0.097 12.5 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Zn_clus PF00172.13 KNZ73181.1 - 0.14 12.1 5.7 2.9 7.8 0.4 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NPV_P10 PF05531.7 KNZ73184.1 - 0.36 11.1 1.0 0.86 9.8 0.7 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein A_deaminase PF00962.17 KNZ73185.1 - 9.8e-111 369.8 0.3 1.2e-110 369.5 0.2 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Methyltransf_2 PF00891.13 KNZ73186.1 - 5.3e-26 91.2 0.0 7.8e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KNZ73186.1 - 0.00032 20.4 0.2 0.0011 18.7 0.1 2.1 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_18 PF12847.2 KNZ73186.1 - 0.0091 16.5 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KNZ73186.1 - 0.13 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase UQ_con PF00179.21 KNZ73187.1 - 2.7e-11 43.0 0.0 5.4e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ebp2 PF05890.7 KNZ73188.1 - 1.1e-77 260.9 10.5 1.1e-77 260.9 7.3 1.7 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Asp PF00026.18 KNZ73189.1 - 1e-38 133.3 0.1 1.3e-38 133.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNZ73189.1 - 0.16 11.9 0.5 2 8.3 0.4 2.3 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal WD40 PF00400.27 KNZ73190.1 - 1.2e-14 53.5 9.1 2.8e-07 30.1 0.1 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF2419 PF10343.4 KNZ73191.1 - 4.4e-83 278.8 0.0 6.7e-83 278.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Ribonuc_red_lgC PF02867.10 KNZ73193.1 - 1.8e-209 696.8 0.0 3.3e-209 695.9 0.0 1.4 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KNZ73193.1 - 1.4e-24 85.7 0.0 4.1e-24 84.1 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KNZ73193.1 - 4.4e-13 49.4 0.2 8.5e-12 45.3 0.1 2.6 2 0 0 2 2 2 1 ATP cone domain Dor1 PF04124.7 KNZ73194.1 - 0.018 13.5 1.4 0.045 12.2 1.2 1.5 1 1 1 2 2 2 0 Dor1-like family DUF3735 PF12537.3 KNZ73196.1 - 0.081 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) F-box-like PF12937.2 KNZ73197.1 - 0.019 14.7 2.4 0.064 13.0 1.7 2.0 1 1 0 1 1 1 0 F-box-like RecO_C PF02565.10 KNZ73197.1 - 0.022 14.6 0.0 0.075 12.8 0.0 1.9 2 0 0 2 2 2 0 Recombination protein O C terminal Methyltransf_33 PF10017.4 KNZ73198.1 - 5.9e-33 113.4 0.1 1.1e-32 112.6 0.1 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 KNZ73198.1 - 2.1e-22 79.7 0.1 9.9e-12 44.7 0.0 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KNZ73198.1 - 2.5e-06 27.8 1.3 4.9e-06 26.9 0.9 1.5 1 0 0 1 1 1 1 DinB superfamily zf-DHHC PF01529.15 KNZ73199.1 - 2.4e-41 141.0 0.1 3.5e-41 140.4 0.1 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase DZR PF12773.2 KNZ73199.1 - 1.4 8.7 8.8 2.7 7.8 6.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon 4HBT_3 PF13622.1 KNZ73200.1 - 8.3e-32 110.9 1.0 9.7e-32 110.6 0.7 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT_3 PF13622.1 KNZ73201.1 - 1.3e-40 139.8 0.2 1.5e-40 139.5 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KNZ73201.1 - 0.007 16.4 0.1 0.038 14.0 0.0 2.2 2 0 0 2 2 2 1 Thioesterase superfamily Dynactin_p62 PF05502.8 KNZ73202.1 - 1.8e-53 182.0 0.0 2.7e-32 112.2 0.0 2.1 1 1 1 2 2 2 2 Dynactin p62 family NicO PF03824.11 KNZ73203.1 - 0.046 13.0 0.0 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 High-affinity nickel-transport protein DUF680 PF05079.7 KNZ73206.1 - 2.9 8.4 8.8 0.5 10.8 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF680) Asp PF00026.18 KNZ73208.1 - 1.5e-11 44.1 0.0 1.9e-10 40.4 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp PF00026.18 KNZ73209.1 - 2.3e-23 82.9 3.6 1.4e-21 77.0 2.5 2.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KNZ73209.1 - 6.1e-07 29.8 1.7 1.4e-05 25.4 0.4 3.0 2 1 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.1 KNZ73209.1 - 0.0017 18.3 0.4 0.073 13.0 0.3 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 KNZ73209.1 - 0.002 17.9 0.0 0.0067 16.2 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Orthoreo_P10 PF07204.6 KNZ73209.1 - 0.0088 15.7 0.1 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Herpes_gE PF02480.11 KNZ73209.1 - 0.093 10.9 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Heme_oxygenase PF01126.15 KNZ73210.1 - 1.6e-41 142.1 0.0 2.8e-41 141.3 0.0 1.4 1 1 0 1 1 1 1 Heme oxygenase Heme_oxygenase PF01126.15 KNZ73211.1 - 6.8e-36 123.7 0.0 9.3e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Heme oxygenase zf-RING_2 PF13639.1 KNZ73213.1 - 2.3e-14 52.9 6.0 5.2e-14 51.7 4.2 1.6 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KNZ73213.1 - 5.2e-10 38.9 0.0 9.3e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 KNZ73213.1 - 7.4e-08 32.3 5.2 1.8e-07 31.1 3.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KNZ73213.1 - 1.2e-06 28.1 5.1 2.5e-06 27.0 3.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KNZ73213.1 - 4.1e-05 23.5 7.2 0.00011 22.1 5.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNZ73213.1 - 0.00017 21.1 3.7 0.0004 19.9 2.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ73213.1 - 0.00037 20.0 6.5 0.00095 18.7 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KNZ73213.1 - 0.039 13.7 5.0 0.21 11.4 3.5 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HyaE PF07449.6 KNZ73213.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE zf-Nse PF11789.3 KNZ73213.1 - 0.2 11.2 3.7 0.49 9.9 2.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Corona_S2 PF01601.11 KNZ73213.1 - 0.23 9.5 0.1 0.33 8.9 0.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Tom37 PF10568.4 KNZ73213.1 - 0.31 11.3 2.3 2.8 8.2 0.1 3.1 3 0 0 3 3 3 0 Outer mitochondrial membrane transport complex protein zf-RING_UBOX PF13445.1 KNZ73213.1 - 3.6 7.3 6.5 1.7 8.4 1.2 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Glyco_hydro_15 PF00723.16 KNZ73214.1 - 6.1e-89 298.6 0.2 7.4e-89 298.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KNZ73214.1 - 5.9e-25 86.7 0.0 1.5e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain DUF500 PF04366.7 KNZ73215.1 - 3.2e-45 152.6 0.0 5.4e-45 151.8 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) DUF500 PF04366.7 KNZ73216.1 - 5.6e-30 103.3 0.0 8.7e-30 102.7 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) DUF500 PF04366.7 KNZ73217.1 - 2.3e-12 46.4 0.0 5e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) Pkinase PF00069.20 KNZ73217.1 - 0.16 11.0 0.0 0.38 9.8 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain Phosphodiest PF01663.17 KNZ73218.1 - 5.9e-69 233.1 0.7 7.6e-69 232.7 0.5 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KNZ73218.1 - 0.00072 18.8 0.0 0.24 10.5 0.0 2.2 2 0 0 2 2 2 2 Sulfatase RNase_H PF00075.19 KNZ73219.1 - 1.9e-05 25.0 0.0 3.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 RNase H Pkinase PF00069.20 KNZ73221.1 - 5.8e-15 55.1 0.0 1.1e-10 41.1 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73221.1 - 1e-05 24.7 0.0 0.00019 20.6 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KNZ73221.1 - 0.021 14.5 7.9 1.6 8.4 0.4 4.4 3 2 2 5 5 5 0 Phosphotransferase enzyme family Kdo PF06293.9 KNZ73221.1 - 0.93 8.5 2.4 16 4.4 0.2 3.0 4 0 0 4 4 4 0 Lipopolysaccharide kinase (Kdo/WaaP) family vWA-TerF-like PF10138.4 KNZ73222.1 - 0.009 15.8 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus CagY_I PF14585.1 KNZ73224.1 - 0.057 13.3 0.3 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 CagY type 1 repeat AAA_5 PF07728.9 KNZ73225.1 - 6.9e-117 385.4 0.0 8.6e-21 74.1 0.0 10.2 9 1 1 10 10 10 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KNZ73225.1 - 2.6e-21 75.6 0.0 1.2e-06 28.1 0.0 6.9 8 0 0 8 8 6 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KNZ73225.1 - 5.4e-21 75.1 0.1 0.00028 21.0 0.0 7.4 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KNZ73225.1 - 2.6e-16 59.9 0.8 0.0061 16.7 0.0 7.2 7 0 0 7 7 6 4 AAA domain Sigma54_activ_2 PF14532.1 KNZ73225.1 - 7.5e-14 51.9 0.9 0.00063 19.8 0.0 6.4 7 0 0 7 7 5 2 Sigma-54 interaction domain AAA_14 PF13173.1 KNZ73225.1 - 7.6e-14 51.7 0.0 0.0013 18.6 0.0 7.0 7 0 0 7 7 6 2 AAA domain AAA_17 PF13207.1 KNZ73225.1 - 1e-13 52.1 0.0 0.16 12.7 0.0 7.2 7 0 0 7 7 6 3 AAA domain AAA_16 PF13191.1 KNZ73225.1 - 1.2e-13 51.4 21.2 0.00064 19.7 0.0 9.1 9 1 0 9 9 8 3 AAA ATPase domain Sigma54_activat PF00158.21 KNZ73225.1 - 3.3e-13 49.4 0.0 0.024 14.0 0.0 5.0 4 0 0 4 4 4 4 Sigma-54 interaction domain AAA_18 PF13238.1 KNZ73225.1 - 5.7e-13 49.3 3.7 0.082 13.2 0.0 6.9 6 0 0 6 6 6 3 AAA domain T2SE PF00437.15 KNZ73225.1 - 2e-09 36.7 4.0 0.062 12.1 0.0 6.5 7 0 0 7 7 7 2 Type II/IV secretion system protein AAA_19 PF13245.1 KNZ73225.1 - 2.3e-09 36.8 4.1 0.011 15.5 0.1 5.4 5 0 0 5 5 5 1 Part of AAA domain Mg_chelatase PF01078.16 KNZ73225.1 - 8.4e-08 31.6 0.1 2.1 7.4 0.0 6.7 7 0 0 7 7 7 1 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 KNZ73225.1 - 1.1e-07 31.4 0.2 2.9 7.5 0.0 5.5 5 0 0 5 5 5 2 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KNZ73225.1 - 2.3e-07 31.1 3.9 0.38 11.0 0.0 5.9 7 0 0 7 7 4 2 ABC transporter AAA_33 PF13671.1 KNZ73225.1 - 2.5e-07 30.6 0.1 0.52 10.1 0.0 6.1 7 0 0 7 7 5 1 AAA domain Miro PF08477.8 KNZ73225.1 - 1.4e-06 28.8 0.4 4 7.9 0.0 5.5 5 0 0 5 5 5 0 Miro-like protein NACHT PF05729.7 KNZ73225.1 - 2e-06 27.5 0.3 1.6 8.3 0.0 4.7 5 0 0 5 5 4 2 NACHT domain AAA_29 PF13555.1 KNZ73225.1 - 3.7e-06 26.3 2.7 1.4 8.5 0.1 5.4 6 0 0 6 6 6 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 KNZ73225.1 - 3.9e-06 26.9 0.6 15 5.8 0.0 6.1 7 0 0 7 7 5 0 RNA helicase AAA_28 PF13521.1 KNZ73225.1 - 2.1e-05 24.5 3.9 3.1 7.7 0.0 5.4 6 0 0 6 6 4 1 AAA domain DUF815 PF05673.8 KNZ73225.1 - 3.1e-05 23.0 0.1 4.5 6.1 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 KNZ73225.1 - 3.2e-05 23.1 0.0 3.5 6.6 0.0 5.0 4 0 0 4 4 4 1 Zeta toxin MobB PF03205.9 KNZ73225.1 - 0.00031 20.4 1.4 10 5.7 0.0 5.0 5 0 0 5 5 5 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KNZ73225.1 - 0.00052 19.4 2.6 6.5 6.0 0.1 5.2 6 0 0 6 6 5 0 AAA domain PduV-EutP PF10662.4 KNZ73225.1 - 0.0016 17.9 0.9 1.3 8.5 0.0 4.5 5 0 0 5 5 4 1 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.7 KNZ73225.1 - 0.0023 17.0 0.4 2.7 6.9 0.0 3.9 4 0 0 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus DUF258 PF03193.11 KNZ73225.1 - 0.0078 15.4 0.3 13 4.9 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function, DUF258 ResIII PF04851.10 KNZ73225.1 - 0.015 15.1 1.8 7 6.4 0.0 4.0 4 0 0 4 4 2 0 Type III restriction enzyme, res subunit SRP54 PF00448.17 KNZ73225.1 - 0.015 14.7 0.4 11 5.4 0.0 3.7 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain DEAD PF00270.24 KNZ73225.1 - 0.024 14.1 0.3 7.3 6.0 0.0 3.9 4 0 0 4 4 3 0 DEAD/DEAH box helicase KaiC PF06745.8 KNZ73225.1 - 0.032 13.3 0.1 4.3 6.3 0.0 3.1 3 0 0 3 3 3 0 KaiC NTPase_1 PF03266.10 KNZ73225.1 - 0.062 13.0 3.2 9.3 5.9 0.1 4.8 6 0 0 6 6 5 0 NTPase AAA_24 PF13479.1 KNZ73225.1 - 0.086 12.4 0.5 69 2.9 0.0 3.8 4 0 0 4 4 3 0 AAA domain PhoH PF02562.11 KNZ73225.1 - 0.14 11.3 0.1 22 4.1 0.0 3.2 3 0 0 3 3 3 0 PhoH-like protein TIP49 PF06068.8 KNZ73225.1 - 0.24 10.0 0.1 7.2 5.2 0.0 2.8 3 0 0 3 3 3 0 TIP49 C-terminus cobW PF02492.14 KNZ73225.1 - 0.24 10.7 2.1 54 3.1 0.0 4.2 5 0 0 5 5 4 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 KNZ73225.1 - 0.38 10.7 0.8 1.2e+02 2.6 0.0 4.5 5 0 0 5 5 4 0 50S ribosome-binding GTPase AAA_6 PF12774.2 KNZ73225.1 - 1.1 8.7 0.0 77 2.6 0.0 3.5 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region D1 Pkinase_Tyr PF07714.12 KNZ73227.1 - 7.4e-37 126.8 0.0 9.1e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ73227.1 - 8.3e-36 123.4 0.0 1.1e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KNZ73227.1 - 0.0063 16.2 0.6 0.019 14.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KNZ73227.1 - 0.092 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like KAP PF05804.7 KNZ73227.1 - 0.13 10.2 0.0 0.17 9.7 0.0 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Kdo PF06293.9 KNZ73227.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phytase-like PF13449.1 KNZ73229.1 - 5.9e-22 78.3 0.1 1.3e-21 77.2 0.0 1.5 2 0 0 2 2 2 1 Esterase-like activity of phytase SdiA-regulated PF06977.6 KNZ73229.1 - 0.14 11.0 0.0 0.9 8.4 0.0 2.0 1 1 0 1 1 1 0 SdiA-regulated Abhydrolase_6 PF12697.2 KNZ73231.1 - 3.5e-28 99.0 0.0 4.6e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ73231.1 - 2.1e-13 50.2 0.0 3.3e-13 49.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ73231.1 - 2.2e-13 50.3 0.0 4e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.15 KNZ73231.1 - 8.2e-09 36.0 0.0 1.2e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 KNZ73231.1 - 1.8e-08 34.2 0.0 4.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.3 KNZ73231.1 - 1e-05 25.2 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 KNZ73231.1 - 0.00099 18.7 0.1 0.0021 17.6 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 KNZ73231.1 - 0.007 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase PF07224.6 KNZ73231.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF829 PF05705.9 KNZ73231.1 - 0.017 14.8 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Chlorophyllase2 PF12740.2 KNZ73231.1 - 0.023 13.6 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 KNZ73231.1 - 0.026 14.0 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 KNZ73231.1 - 0.038 13.4 0.1 0.069 12.5 0.1 1.5 1 1 0 1 1 1 0 Putative esterase DUF915 PF06028.6 KNZ73231.1 - 0.13 11.3 0.2 6.1 5.8 0.1 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF1057 PF06342.7 KNZ73231.1 - 0.16 10.7 0.3 0.37 9.5 0.0 1.6 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Phytase-like PF13449.1 KNZ73232.1 - 4.1e-21 75.6 0.0 7.5e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Esterase-like activity of phytase SWI-SNF_Ssr4 PF08549.5 KNZ73233.1 - 7.1e-17 60.9 3.5 5.8e-16 57.9 2.4 2.0 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) TSC22 PF01166.13 KNZ73233.1 - 0.17 11.8 0.2 0.17 11.8 0.2 1.8 2 0 0 2 2 2 0 TSC-22/dip/bun family Atg14 PF10186.4 KNZ73233.1 - 0.61 8.9 3.5 0.62 8.9 0.0 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KNZ73233.1 - 1.4 8.4 6.9 6 6.4 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator Pkinase PF00069.20 KNZ73234.1 - 6.8e-42 143.4 0.0 1.3e-41 142.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73234.1 - 1e-25 90.2 0.0 3.3e-24 85.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ73234.1 - 0.095 11.6 0.0 11 4.9 0.0 2.2 2 0 0 2 2 2 0 Kinase-like CTP_synth_N PF06418.9 KNZ73236.1 - 0.12 11.4 0.0 0.13 11.3 0.0 1.0 1 0 0 1 1 1 0 CTP synthase N-terminus ThylakoidFormat PF11264.3 KNZ73237.1 - 0.011 15.3 0.2 0.015 14.9 0.1 1.1 1 0 0 1 1 1 0 Thylakoid formation protein RVP_2 PF08284.6 KNZ73238.1 - 0.00033 20.6 0.0 0.00043 20.2 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease PAS_10 PF13596.1 KNZ73241.1 - 0.093 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 PAS domain RNase_H PF00075.19 KNZ73242.1 - 1.9e-07 31.5 0.1 3.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 RNase H 1-cysPrx_C PF10417.4 KNZ73243.1 - 0.004 16.7 0.1 0.0066 16.0 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin F-box PF00646.28 KNZ73244.1 - 0.00029 20.4 2.4 0.00043 19.8 0.1 2.5 2 0 0 2 2 2 1 F-box domain Sigma70_ner PF04546.8 KNZ73245.1 - 0.0041 16.7 3.0 0.0064 16.1 2.1 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region F-box-like PF12937.2 KNZ73245.1 - 0.018 14.7 0.1 0.24 11.1 0.0 2.9 3 1 0 3 3 3 0 F-box-like NOA36 PF06524.7 KNZ73245.1 - 0.45 9.7 1.3 0.66 9.1 0.9 1.2 1 0 0 1 1 1 0 NOA36 protein FMN_red PF03358.10 KNZ73246.1 - 4.2e-08 32.8 0.0 6.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 KNZ73246.1 - 4.4e-08 33.2 0.0 7.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 KNZ73246.1 - 4.6e-07 29.5 0.0 6.5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Amidase PF01425.16 KNZ73247.1 - 6.1e-84 282.4 0.0 7.5e-84 282.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Spore_coat_CotO PF14153.1 KNZ73247.1 - 0.2 11.1 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO zf-MYND PF01753.13 KNZ73248.1 - 1.4e-10 40.8 11.5 1.4e-10 40.8 7.9 3.0 2 1 1 3 3 3 1 MYND finger SET PF00856.23 KNZ73248.1 - 8e-08 32.7 0.0 2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 SET domain DUF563 PF04577.9 KNZ73249.1 - 1.5e-20 73.9 0.4 4.8e-20 72.3 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF563) TFIIA_gamma_N PF02268.11 KNZ73250.1 - 3.5e-26 90.5 0.1 5.2e-26 89.9 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 KNZ73250.1 - 1.4e-23 82.4 0.2 2e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Scytalone_dh PF02982.9 KNZ73250.1 - 0.029 13.9 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Scytalone dehydratase LRR_4 PF12799.2 KNZ73251.1 - 0.053 13.1 11.3 11 5.7 0.0 5.6 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) Orthopox_A5L PF06193.6 KNZ73251.1 - 0.069 13.0 0.2 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Blo-t-5 PF11642.3 KNZ73251.1 - 0.13 12.0 0.1 0.62 9.8 0.0 1.9 2 0 0 2 2 2 0 Mite allergen Blo t 5 LRR_6 PF13516.1 KNZ73251.1 - 0.13 12.3 4.8 1.4e+02 3.0 0.1 5.7 7 0 0 7 7 7 0 Leucine Rich repeat Pkinase PF00069.20 KNZ73253.1 - 0.018 14.2 0.0 0.3 10.1 0.0 2.0 1 1 0 1 1 1 0 Protein kinase domain Amidase PF01425.16 KNZ73254.1 - 3e-76 257.0 0.0 3.4e-74 250.3 0.0 2.0 1 1 0 1 1 1 1 Amidase DUF563 PF04577.9 KNZ73255.1 - 1.7e-23 83.6 0.1 2.4e-23 83.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) EcoR124_C PF12008.3 KNZ73256.1 - 0.041 13.0 0.6 0.045 12.9 0.4 1.0 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal DDE_Tnp_1_7 PF13843.1 KNZ73256.1 - 0.14 11.1 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Transposase IS4 Shikimate_dh_N PF08501.6 KNZ73257.1 - 4e-11 42.8 0.0 9.2e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KNZ73257.1 - 3e-06 27.3 0.0 5.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KNZ73257.1 - 0.093 12.7 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Sugar_tr PF00083.19 KNZ73258.1 - 1.7e-112 376.2 32.1 2e-112 376.0 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ73258.1 - 2.7e-20 72.4 48.4 4e-20 71.8 28.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_isomerase PF00160.16 KNZ73259.1 - 1.1e-40 139.4 0.2 1.2e-40 139.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.16 KNZ73260.1 - 6.7e-45 153.0 0.5 7.3e-45 152.9 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.16 KNZ73261.1 - 2.8e-45 154.2 0.8 3.1e-45 154.1 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M28 PF04389.12 KNZ73262.1 - 6.2e-17 61.8 0.0 8.8e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 RRM_1 PF00076.17 KNZ73264.1 - 3.4e-09 36.2 0.0 9.9e-05 21.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ73264.1 - 6.8e-07 29.1 0.0 0.0008 19.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ73264.1 - 0.0014 18.4 0.0 0.84 9.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KNZ73265.1 - 1.8e-35 122.3 0.0 3.5e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73265.1 - 5e-31 107.7 0.0 9.1e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2937 PF11157.3 KNZ73265.1 - 0.0035 16.6 1.2 0.0069 15.7 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2937) RIO1 PF01163.17 KNZ73265.1 - 0.029 13.7 1.5 0.67 9.2 0.0 3.0 3 0 0 3 3 3 0 RIO1 family CAF-1_p150 PF11600.3 KNZ73265.1 - 0.55 9.5 53.4 0.01 15.2 26.6 2.6 2 1 1 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Atg14 PF10186.4 KNZ73265.1 - 9.6 5.0 18.1 25 3.6 12.5 1.7 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RNase_H PF00075.19 KNZ73266.1 - 2.3e-19 70.0 0.1 4.3e-19 69.1 0.1 1.4 1 0 0 1 1 1 1 RNase H HTH_45 PF14947.1 KNZ73266.1 - 0.01 15.6 0.2 0.051 13.3 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix zf-RVT PF13966.1 KNZ73266.1 - 0.015 15.5 3.0 0.046 14.0 2.1 1.9 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase Pkinase PF00069.20 KNZ73267.1 - 2.7e-44 151.2 0.0 4.4e-26 91.5 0.0 2.7 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73267.1 - 1.5e-43 148.7 0.0 2e-23 82.7 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Radical_SAM PF04055.16 KNZ73267.1 - 0.062 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Radical SAM superfamily MtrF PF09472.5 KNZ73267.1 - 0.12 11.6 0.2 0.34 10.1 0.0 1.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Dioxygenase_C PF00775.16 KNZ73269.1 - 2.6e-57 193.0 0.0 3.8e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KNZ73269.1 - 1.3e-19 69.8 0.0 2.4e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KNZ73269.1 - 0.00019 21.4 0.0 0.00066 19.6 0.0 1.9 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Fe-ADH PF00465.14 KNZ73270.1 - 3e-73 246.5 5.4 3.4e-73 246.4 3.7 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KNZ73270.1 - 2.6e-16 59.6 0.6 3.7e-16 59.2 0.4 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AIRC PF00731.15 KNZ73270.1 - 0.007 15.6 0.1 0.021 14.0 0.0 1.9 1 0 0 1 1 1 1 AIR carboxylase NAD_kinase PF01513.16 KNZ73270.1 - 0.018 13.8 0.1 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase Prok-RING_2 PF14445.1 KNZ73270.1 - 0.097 12.6 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Oxidored-like PF09791.4 KNZ73272.1 - 8.2e-14 50.7 0.6 1.8e-13 49.7 0.4 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal ComX PF05952.7 KNZ73272.1 - 0.013 14.9 0.0 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Bacillus competence pheromone ComX Bombinin PF05298.6 KNZ73272.1 - 0.051 13.0 0.1 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Bombinin OmpH PF03938.9 KNZ73272.1 - 0.074 12.9 0.0 0.096 12.6 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MbeB_N PF04837.7 KNZ73272.1 - 0.45 10.6 3.8 1.1 9.4 0.4 2.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region LRR_4 PF12799.2 KNZ73273.1 - 0.14 11.8 8.0 3.9 7.2 0.1 4.8 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) Ribosomal_L18ae PF01775.12 KNZ73274.1 - 2.1e-47 160.0 0.9 2.7e-47 159.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Methyltransf_23 PF13489.1 KNZ73275.1 - 1.4e-23 83.3 0.0 2.1e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ73275.1 - 2.2e-18 66.3 0.0 3.1e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ73275.1 - 3.7e-18 65.8 0.0 5.5e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ73275.1 - 5.5e-16 59.1 0.0 8.3e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ73275.1 - 1.1e-15 57.8 0.0 1.7e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ73275.1 - 1.2e-09 38.4 0.0 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KNZ73275.1 - 1.3e-09 37.5 0.0 1.8e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KNZ73275.1 - 1.7e-07 31.2 0.0 3.7e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KNZ73275.1 - 4.5e-07 29.2 0.0 6.7e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KNZ73275.1 - 1.6e-06 27.3 0.0 2.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KNZ73275.1 - 8e-06 25.3 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 KNZ73275.1 - 1.1e-05 24.3 0.0 1.6e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.6 KNZ73275.1 - 0.0045 16.3 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 KNZ73275.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 KNZ73275.1 - 0.017 14.2 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB TPMT PF05724.6 KNZ73275.1 - 0.021 14.2 0.0 0.072 12.5 0.0 1.8 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.7 KNZ73275.1 - 0.03 13.6 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DREV PF05219.7 KNZ73275.1 - 0.071 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase AdoMet_MTase PF07757.8 KNZ73275.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase JAB PF01398.16 KNZ73276.1 - 5.1e-27 93.8 0.0 1e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KNZ73276.1 - 8.8e-07 28.4 0.0 2.1e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain DUF4404 PF14357.1 KNZ73276.1 - 0.00078 19.8 0.5 0.0016 18.7 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4404) Pilt PF15453.1 KNZ73276.1 - 0.024 14.3 0.4 0.033 13.8 0.3 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions PseudoU_synth_1 PF01416.15 KNZ73277.1 - 3.6e-25 88.4 0.0 6.2e-15 55.5 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase DHHW PF14286.1 KNZ73279.1 - 0.0052 16.1 2.8 0.0064 15.8 2.0 1.2 1 0 0 1 1 1 1 DHHW protein CpeS PF09367.5 KNZ73279.1 - 0.029 14.2 1.5 0.035 14.0 1.0 1.2 1 0 0 1 1 1 0 CpeS-like protein NPR3 PF03666.8 KNZ73279.1 - 0.12 10.9 1.4 0.12 10.8 0.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2201_N PF13203.1 KNZ73279.1 - 0.21 10.7 4.8 0.24 10.5 3.4 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain RP-C_C PF11800.3 KNZ73279.1 - 0.35 10.5 5.1 0.45 10.1 3.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Na_trans_assoc PF06512.8 KNZ73279.1 - 0.6 10.0 10.6 0.67 9.8 7.3 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated DUF1510 PF07423.6 KNZ73279.1 - 0.67 9.2 13.2 0.84 8.9 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Trypan_PARP PF05887.6 KNZ73279.1 - 0.94 9.2 4.2 1.1 9.0 2.9 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3682 PF12446.3 KNZ73279.1 - 1.1 9.5 15.1 1.4 9.1 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF3295 PF11702.3 KNZ73279.1 - 1.4 7.8 12.6 1.5 7.7 8.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF789 PF05623.7 KNZ73279.1 - 1.4 8.3 7.1 1.7 8.0 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) NOA36 PF06524.7 KNZ73279.1 - 3.3 6.8 13.0 3.8 6.6 9.0 1.3 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.8 KNZ73279.1 - 4.2 7.1 16.3 4.7 7.0 11.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 KNZ73279.1 - 6 4.7 17.1 7.5 4.4 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 KNZ73279.1 - 6.9 6.1 19.6 8.9 5.7 13.6 1.1 1 0 0 1 1 1 0 PPP4R2 RVP_2 PF08284.6 KNZ73281.1 - 0.05 13.5 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease FLYWCH PF04500.11 KNZ73281.1 - 0.29 11.0 3.3 0.57 10.1 2.3 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain SGL PF08450.7 KNZ73283.1 - 1e-14 54.5 0.0 1.5e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KNZ73283.1 - 0.0098 15.8 0.0 0.033 14.1 0.0 1.9 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.11 KNZ73283.1 - 0.15 12.1 0.0 0.48 10.4 0.0 1.8 2 0 0 2 2 2 0 Strictosidine synthase Cullin PF00888.17 KNZ73286.1 - 1.9e-123 413.0 21.4 2.6e-123 412.6 14.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KNZ73286.1 - 1.7e-17 63.0 0.9 7.6e-17 60.9 0.6 2.3 1 0 0 1 1 1 1 Cullin protein neddylation domain SNF2_N PF00176.18 KNZ73286.1 - 0.028 13.2 0.9 0.047 12.4 0.1 1.8 2 0 0 2 2 2 0 SNF2 family N-terminal domain Rrf2 PF02082.15 KNZ73286.1 - 0.07 13.2 0.1 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 Transcriptional regulator Pkinase PF00069.20 KNZ73287.1 - 2.2e-41 141.7 0.0 4.1e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73287.1 - 6.5e-38 130.2 0.0 1e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KNZ73287.1 - 0.0049 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KNZ73289.1 - 1.3e-39 135.9 0.0 2.2e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73289.1 - 1.9e-34 118.9 0.0 3e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KNZ73289.1 - 0.0047 16.0 0.0 0.0091 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KNZ73289.1 - 0.035 13.4 0.0 0.087 12.1 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 KNZ73289.1 - 0.045 12.7 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 KNZ73290.1 - 3.7e-46 157.3 0.0 7.4e-46 156.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73290.1 - 2.5e-40 138.2 0.0 4.2e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ73290.1 - 0.00046 19.2 0.0 0.001 18.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KNZ73290.1 - 0.00074 18.9 0.0 0.0072 15.6 0.0 2.2 1 1 0 2 2 2 1 RIO1 family Kdo PF06293.9 KNZ73290.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KNZ73290.1 - 0.16 11.3 0.0 0.36 10.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL tRNA-synt_1d PF00750.14 KNZ73292.1 - 3.5e-71 239.8 3.0 1.7e-70 237.6 2.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KNZ73292.1 - 4.5e-24 84.6 0.7 1.2e-23 83.3 0.0 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain Peroxin-13_N PF04088.8 KNZ73293.1 - 6.7e-44 149.6 0.1 1e-43 149.0 0.1 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 KNZ73293.1 - 7.8e-10 37.9 1.7 0.0011 18.3 1.7 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KNZ73293.1 - 1.6e-09 37.1 0.0 2.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KNZ73293.1 - 2e-08 33.7 0.4 4.3e-08 32.6 0.3 1.6 1 1 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.20 KNZ73294.1 - 6.1e-33 114.0 0.0 2.3e-32 112.1 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73294.1 - 6.5e-28 97.4 0.0 4.1e-27 94.8 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ73294.1 - 0.00026 20.0 0.0 0.00064 18.7 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 KNZ73294.1 - 0.0016 17.5 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KNZ73294.1 - 0.007 15.7 0.1 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KNZ73294.1 - 0.012 15.3 0.4 0.056 13.1 0.1 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family GvpH PF05455.6 KNZ73297.1 - 0.011 15.3 0.1 0.027 14.0 0.0 1.7 2 0 0 2 2 2 0 GvpH GMC_oxred_C PF05199.8 KNZ73298.1 - 2e-24 86.5 0.0 2.3e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Zn_Tnp_IS1595 PF12760.2 KNZ73299.1 - 5.1e-05 22.9 4.7 5.1e-05 22.9 3.3 1.6 1 1 1 2 2 2 2 Transposase zinc-ribbon domain zf-FPG_IleRS PF06827.9 KNZ73299.1 - 0.013 15.0 0.7 0.027 14.1 0.5 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zinc_ribbon_2 PF13240.1 KNZ73299.1 - 0.028 13.8 1.4 0.028 13.8 0.9 1.9 2 1 0 2 2 2 0 zinc-ribbon domain RasGEF_N_2 PF14663.1 KNZ73299.1 - 0.091 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain zf-RING_3 PF14369.1 KNZ73299.1 - 0.13 12.2 0.6 0.13 12.2 0.4 2.4 2 1 0 2 2 2 0 zinc-finger zf-ribbon_3 PF13248.1 KNZ73299.1 - 0.17 11.1 1.9 0.44 9.8 1.3 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zf-RING_5 PF14634.1 KNZ73299.1 - 2.1 8.1 7.7 4.6 7.0 5.4 1.7 1 1 0 1 1 1 0 zinc-RING finger domain RVP_2 PF08284.6 KNZ73301.1 - 0.015 15.2 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KNZ73301.1 - 0.031 14.7 0.0 0.038 14.4 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease FHA PF00498.21 KNZ73303.1 - 4.2e-17 62.0 0.0 7e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain FMN_dh PF01070.13 KNZ73304.1 - 6.2e-71 239.1 4.4 3.1e-48 164.4 1.7 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 KNZ73304.1 - 2.9e-06 26.4 0.3 0.00046 19.1 0.0 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KNZ73304.1 - 0.00015 21.0 0.5 0.00023 20.4 0.2 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 KNZ73304.1 - 0.00068 18.6 0.1 0.00097 18.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 KNZ73304.1 - 0.017 14.2 0.1 0.25 10.3 0.0 2.1 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG SKG6 PF08693.5 KNZ73305.1 - 0.042 13.1 0.2 0.12 11.6 0.1 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain COesterase PF00135.23 KNZ73306.1 - 7.3e-100 335.1 0.0 8e-99 331.7 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ73306.1 - 2.5e-05 23.9 0.3 0.0024 17.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KNZ73306.1 - 0.0054 15.9 0.3 0.023 13.9 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.23 KNZ73307.1 - 5.8e-92 309.1 0.0 5.4e-57 193.7 0.0 3.6 2 2 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ73307.1 - 8.9e-06 25.4 0.3 0.0022 17.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KNZ73307.1 - 0.011 14.9 0.2 0.025 13.7 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family AAA PF00004.24 KNZ73308.1 - 2.2e-38 131.4 0.0 3.5e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KNZ73308.1 - 7.5e-07 28.4 0.0 1.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KNZ73308.1 - 7.4e-06 26.7 0.0 2.6e-05 25.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 KNZ73308.1 - 2.6e-05 24.1 0.0 5.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KNZ73308.1 - 2.7e-05 24.3 0.1 0.00078 19.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KNZ73308.1 - 7e-05 22.8 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KNZ73308.1 - 8.3e-05 22.6 0.1 0.0038 17.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KNZ73308.1 - 0.00015 21.6 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KNZ73308.1 - 0.00017 21.3 0.3 0.0016 18.1 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KNZ73308.1 - 0.0003 19.9 0.0 0.00051 19.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 KNZ73308.1 - 0.00054 19.4 0.3 0.0011 18.4 0.1 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KNZ73308.1 - 0.00057 19.1 0.2 0.0025 17.0 0.1 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KNZ73308.1 - 0.001 19.0 0.1 0.0031 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KNZ73308.1 - 0.001 19.3 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KNZ73308.1 - 0.0018 17.0 0.0 0.0027 16.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Sigma54_activ_2 PF14532.1 KNZ73308.1 - 0.0029 17.6 0.0 0.006 16.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.8 KNZ73308.1 - 0.0046 15.7 0.1 0.0086 14.8 0.1 1.4 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 KNZ73308.1 - 0.0055 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 KNZ73308.1 - 0.0072 15.7 0.4 0.11 11.8 0.2 2.4 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 KNZ73308.1 - 0.012 15.2 0.1 0.039 13.6 0.0 1.9 1 1 1 2 2 2 0 NACHT domain AAA_10 PF12846.2 KNZ73308.1 - 0.013 15.0 0.3 0.86 8.9 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain AAA_24 PF13479.1 KNZ73308.1 - 0.026 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KNZ73308.1 - 0.036 14.3 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.13 KNZ73308.1 - 0.053 13.0 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SKI PF01202.17 KNZ73308.1 - 0.065 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase Sigma54_activat PF00158.21 KNZ73308.1 - 0.077 12.4 0.0 0.28 10.6 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 KNZ73308.1 - 0.083 12.6 0.0 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain ATP-synt_ab PF00006.20 KNZ73308.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Guanylate_kin PF00625.16 KNZ73308.1 - 0.11 11.9 0.0 0.85 9.0 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase UPF0079 PF02367.12 KNZ73308.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Bac_DnaA PF00308.13 KNZ73308.1 - 0.14 11.7 0.0 0.49 10.0 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein Arch_ATPase PF01637.13 KNZ73308.1 - 0.17 11.5 0.0 0.7 9.5 0.0 1.8 1 1 1 2 2 2 0 Archaeal ATPase Parvo_NS1 PF01057.12 KNZ73308.1 - 0.18 10.6 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF3753 PF12575.3 KNZ73308.1 - 1.5 8.6 7.0 4.2 7.2 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3753) Terpene_synth_C PF03936.11 KNZ73309.1 - 8.9e-18 64.4 0.0 1.3e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Trehalase PF01204.13 KNZ73310.1 - 1.3e-116 390.2 0.7 8.5e-106 354.5 0.0 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.9 KNZ73310.1 - 0.0023 16.6 1.0 0.0047 15.6 0.7 1.4 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase RRM_1 PF00076.17 KNZ73311.1 - 2.2e-09 36.8 0.0 5.6e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ73311.1 - 0.0016 18.4 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 KNZ73311.1 - 0.02 14.9 0.2 0.054 13.6 0.1 1.6 1 0 0 1 1 1 0 PWI domain PRP1_N PF06424.7 KNZ73312.1 - 5.2e-48 162.7 3.2 5.2e-48 162.7 2.2 2.2 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KNZ73312.1 - 1.5e-23 81.1 37.5 0.033 14.8 0.4 14.8 9 4 7 16 16 16 7 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ73312.1 - 2.8e-23 82.0 16.2 0.00031 21.3 0.0 8.9 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ73312.1 - 1.4e-12 47.7 16.7 0.0067 16.7 0.1 10.0 7 4 2 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ73312.1 - 2.4e-09 36.4 4.5 0.2 11.6 0.0 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ73312.1 - 2.7e-08 33.3 4.2 0.057 13.0 0.3 6.9 6 3 2 8 8 8 2 TPR repeat TPR_12 PF13424.1 KNZ73312.1 - 1.1e-05 25.2 3.3 0.21 11.5 0.0 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ73312.1 - 2.6e-05 24.3 6.3 27 5.5 0.0 8.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ73312.1 - 0.00087 18.9 0.0 19 5.3 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ73312.1 - 0.0014 18.1 0.1 3.1 7.5 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ73312.1 - 0.19 11.6 2.9 1.3 9.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ73312.1 - 7.1 6.5 14.1 5.7 6.8 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF814 PF05670.8 KNZ73313.1 - 2.8e-22 78.3 0.0 4.9e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Methyltransf_31 PF13847.1 KNZ73314.1 - 1.7e-10 40.7 0.0 3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KNZ73314.1 - 3.2e-10 39.6 0.1 5.3e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KNZ73314.1 - 1.3e-09 38.6 0.1 4.1e-09 36.9 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ73314.1 - 1.8e-09 37.9 0.0 5.3e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ73314.1 - 5.8e-08 32.7 0.0 3.7e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ73314.1 - 1.1e-06 28.5 0.0 5.4e-06 26.2 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ73314.1 - 2.6e-05 24.5 0.0 6e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ73314.1 - 5e-05 23.7 0.0 0.00013 22.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ73314.1 - 7.9e-05 22.0 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 KNZ73314.1 - 0.00022 22.0 0.2 0.00067 20.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.11 KNZ73314.1 - 0.00086 18.3 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.15 KNZ73314.1 - 0.034 13.2 0.0 0.093 11.7 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 KNZ73314.1 - 0.11 11.8 0.1 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DIOX_N PF14226.1 KNZ73315.1 - 1.8e-31 109.0 0.0 4.1e-31 107.9 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KNZ73315.1 - 7.2e-19 67.9 0.0 1.2e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HIT PF01230.18 KNZ73316.1 - 7.8e-23 80.8 0.1 1.2e-22 80.2 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KNZ73316.1 - 5.3e-12 45.9 0.1 8.5e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KNZ73316.1 - 0.00016 21.3 0.4 0.00027 20.5 0.2 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 p450 PF00067.17 KNZ73317.1 - 2.4e-67 227.4 0.0 3.2e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RPAP1_C PF08620.5 KNZ73318.1 - 5.2e-19 67.8 0.0 1.1e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KNZ73318.1 - 5.9e-07 28.9 1.7 1.2e-06 28.0 1.2 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal ECM11 PF15463.1 KNZ73318.1 - 0.069 13.4 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Extracellular mutant protein 11 GSH_synth_ATP PF03917.12 KNZ73319.1 - 1.9e-95 319.5 0.0 5.2e-95 318.1 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KNZ73319.1 - 1.7e-32 111.6 0.0 3.2e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase MFS_1 PF07690.11 KNZ73320.1 - 1.8e-26 92.7 26.5 1.8e-26 92.7 18.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 KNZ73321.1 - 1.1e-12 48.1 1.0 3.5e-12 46.5 0.7 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ73321.1 - 2.5e-11 43.8 0.2 2.9e-11 43.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KNZ73321.1 - 0.058 12.5 0.0 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) KR PF08659.5 KNZ73321.1 - 0.17 11.5 0.4 1.1 8.8 0.3 1.9 1 1 0 1 1 1 0 KR domain MFS_1 PF07690.11 KNZ73322.1 - 1.9e-28 99.1 22.1 3.1e-28 98.5 15.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Phosphoesterase PF04185.9 KNZ73323.1 - 2e-29 103.0 2.5 3.4e-28 98.9 1.7 2.1 1 1 0 1 1 1 1 Phosphoesterase family TAP_C PF03943.8 KNZ73325.1 - 4.3e-07 29.2 0.0 8.1e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 KNZ73325.1 - 9.5e-06 25.1 14.0 0.00019 20.9 6.1 2.9 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) UBA_4 PF14555.1 KNZ73325.1 - 0.0003 20.2 0.0 0.0011 18.4 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain LRR_9 PF14580.1 KNZ73325.1 - 0.00043 19.8 0.3 0.0009 18.8 0.2 1.5 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.15 KNZ73325.1 - 0.00052 20.3 0.0 0.44 10.9 0.0 2.8 3 0 0 3 3 3 2 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.1 KNZ73325.1 - 0.038 13.7 9.8 0.6 9.9 6.8 2.6 1 1 0 1 1 1 0 Leucine rich repeat LRR_1 PF00560.28 KNZ73325.1 - 0.044 13.8 6.5 12 6.4 0.2 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 KNZ73325.1 - 0.17 12.1 5.6 11 6.6 0.1 4.1 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 KNZ73325.1 - 0.48 10.6 6.6 11 6.5 0.1 4.1 3 0 0 3 3 3 0 Leucine Rich repeat Ank_2 PF12796.2 KNZ73326.1 - 9.3e-26 89.9 0.4 6.6e-10 39.2 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNZ73326.1 - 1.9e-20 72.8 7.9 1.5e-05 25.3 0.0 6.5 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.25 KNZ73326.1 - 7.8e-17 60.1 10.4 5.4e-08 32.2 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 KNZ73326.1 - 7.3e-15 54.6 8.8 1.1e-05 25.4 0.1 5.6 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ73326.1 - 2.5e-13 48.8 6.3 0.0069 16.5 0.0 7.7 7 0 0 7 7 7 3 Ankyrin repeat NuA4 PF09340.5 KNZ73326.1 - 0.12 11.9 1.0 0.31 10.6 0.7 1.6 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 Vps39_1 PF10366.4 KNZ73327.1 - 3.2e-29 101.1 0.6 5.6e-28 97.1 0.0 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KNZ73327.1 - 3.2e-22 78.7 0.2 6.5e-22 77.7 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 KNZ73327.1 - 4.2e-11 42.6 0.4 7.1e-09 35.4 0.1 2.4 2 0 0 2 2 2 2 Region in Clathrin and VPS CNH PF00780.17 KNZ73327.1 - 4.2e-06 26.3 0.0 0.00024 20.6 0.0 2.7 2 1 0 2 2 2 1 CNH domain DUF2849 PF11011.3 KNZ73327.1 - 0.051 13.8 0.2 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) PQQ_3 PF13570.1 KNZ73327.1 - 0.24 11.7 1.4 2.2 8.6 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain MFS_1 PF07690.11 KNZ73328.1 - 4e-21 75.1 37.3 1.2e-20 73.5 25.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ73328.1 - 4.4e-09 35.4 3.3 4.4e-09 35.4 2.3 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 KNZ73328.1 - 4.1e-06 25.4 14.7 0.0005 18.5 0.4 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein UPF0233 PF06781.7 KNZ73328.1 - 0.22 11.1 1.3 6.2 6.5 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) PhaG_MnhG_YufB PF03334.9 KNZ73328.1 - 0.43 10.6 6.5 0.21 11.6 0.2 3.2 3 0 0 3 3 3 0 Na+/H+ antiporter subunit PIF1 PF05970.9 KNZ73330.1 - 1.5e-15 57.0 0.2 2.2e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.1 KNZ73330.1 - 1.8e-05 24.7 0.0 4e-05 23.6 0.0 1.5 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 KNZ73330.1 - 0.0013 18.8 0.6 0.017 15.2 0.0 2.2 2 1 0 2 2 2 1 RNA helicase ResIII PF04851.10 KNZ73330.1 - 0.0022 17.8 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NB-ARC PF00931.17 KNZ73330.1 - 0.0048 15.8 0.0 0.0077 15.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.1 KNZ73330.1 - 0.01 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KNZ73330.1 - 0.011 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 KNZ73330.1 - 0.011 16.0 1.9 0.018 15.3 0.2 1.9 1 1 1 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.13 KNZ73330.1 - 0.014 14.8 0.0 0.026 14.0 0.0 1.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.4 KNZ73330.1 - 0.015 14.3 0.2 0.025 13.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 KNZ73330.1 - 0.02 14.6 0.1 0.03 14.0 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain DUF2493 PF10686.4 KNZ73330.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) AAA PF00004.24 KNZ73330.1 - 0.023 14.9 1.8 0.072 13.2 0.1 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KNZ73330.1 - 0.029 13.9 0.7 0.045 13.2 0.5 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 KNZ73330.1 - 0.046 12.6 0.0 0.059 12.2 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 KNZ73330.1 - 0.053 13.6 0.4 0.13 12.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain Zein-binding PF04576.10 KNZ73330.1 - 0.056 13.5 0.6 0.092 12.8 0.4 1.3 1 0 0 1 1 1 0 Zein-binding UPF0079 PF02367.12 KNZ73330.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 KNZ73330.1 - 0.071 11.7 0.0 0.1 11.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Torsin PF06309.6 KNZ73330.1 - 0.073 12.9 0.1 0.28 11.0 0.0 1.9 2 1 0 2 2 2 0 Torsin AAA_18 PF13238.1 KNZ73330.1 - 0.074 13.3 3.8 0.077 13.3 0.1 2.3 2 1 0 2 2 2 0 AAA domain SRP_SPB PF02978.14 KNZ73330.1 - 0.081 13.1 0.4 0.44 10.8 0.3 1.9 1 1 0 1 1 1 0 Signal peptide binding domain AAA_28 PF13521.1 KNZ73330.1 - 0.088 12.7 1.4 0.37 10.7 0.2 2.1 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KNZ73330.1 - 0.11 11.5 0.7 1.3 8.0 0.1 2.0 1 1 1 2 2 2 0 KaiC AAA_14 PF13173.1 KNZ73330.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KNZ73330.1 - 0.13 11.9 0.1 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 KNZ73330.1 - 0.13 11.6 0.5 0.26 10.6 0.2 1.6 1 1 1 2 2 2 0 AAA domain Med29 PF11568.3 KNZ73330.1 - 0.13 12.2 0.3 0.82 9.7 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 29 Thymidylate_kin PF02223.12 KNZ73330.1 - 0.18 11.1 0.8 4.7 6.5 0.0 2.1 1 1 1 2 2 2 0 Thymidylate kinase AAA_17 PF13207.1 KNZ73330.1 - 0.2 12.4 0.5 0.2 12.4 0.3 2.1 2 1 0 2 2 2 0 AAA domain DUF4112 PF13430.1 KNZ73331.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) CBF PF03914.12 KNZ73331.1 - 0.038 13.4 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 CBF/Mak21 family Glyco_hydro_17 PF00332.13 KNZ73332.1 - 8.1e-09 34.9 0.0 2.1e-07 30.3 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF3844 PF12955.2 KNZ73332.1 - 0.047 13.8 0.0 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) DUF202 PF02656.10 KNZ73333.1 - 1.4 9.1 5.6 2.5 8.3 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Cellulase PF00150.13 KNZ73334.1 - 2.7e-15 56.3 0.2 2.7e-15 56.3 0.1 2.2 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.20 KNZ73335.1 - 8.1e-33 113.6 0.0 3.9e-32 111.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73335.1 - 3.7e-16 58.9 0.0 7.7e-07 28.4 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KNZ73335.1 - 0.013 15.2 3.2 0.058 13.1 0.3 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KNZ73335.1 - 0.084 11.8 0.0 0.68 8.8 0.0 2.3 3 0 0 3 3 3 0 Kinase-like PIF1 PF05970.9 KNZ73336.1 - 9.4e-30 103.7 0.1 1.2e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 KNZ73336.1 - 5.1e-07 27.8 0.0 6.2e-07 27.5 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ73336.1 - 0.0056 16.8 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.9 KNZ73337.1 - 5.6e-13 48.5 0.1 6.8e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Viral_helicase1 PF01443.13 KNZ73337.1 - 0.055 12.9 0.1 0.065 12.7 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.6 KNZ73337.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Torsin DUF457 PF04307.9 KNZ73338.1 - 0.038 13.3 0.3 0.054 12.8 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) UPF0261 PF06792.6 KNZ73338.1 - 0.072 11.5 0.3 0.089 11.2 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) zf-RVT PF13966.1 KNZ73339.1 - 0.026 14.8 1.7 0.036 14.3 1.2 1.3 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Glyco_hydro_17 PF00332.13 KNZ73340.1 - 1.1e-07 31.1 0.0 1.3e-07 30.9 0.0 1.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Peptidase_M56 PF05569.6 KNZ73341.1 - 0.29 10.0 3.8 0.22 10.4 0.2 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF4239 PF14023.1 KNZ73341.1 - 0.67 9.2 3.9 2 7.7 2.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Herpes_Helicase PF02689.9 KNZ73343.1 - 2.1e-06 25.8 0.0 2.2e-06 25.7 0.0 1.0 1 0 0 1 1 1 1 Helicase E1-E2_ATPase PF00122.15 KNZ73345.1 - 2.3e-45 154.4 0.5 2.3e-45 154.4 0.4 2.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KNZ73345.1 - 1.5e-38 132.1 8.0 1.5e-38 132.1 5.5 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KNZ73345.1 - 6.2e-21 75.8 0.0 7e-20 72.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KNZ73345.1 - 6.2e-19 67.7 0.0 1.5e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KNZ73345.1 - 2e-12 47.7 0.0 8.2e-12 45.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KNZ73345.1 - 6.1e-08 32.0 0.3 5.9e-06 25.6 0.0 2.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF2360 PF10152.4 KNZ73346.1 - 0.018 15.3 3.8 0.031 14.5 0.1 2.5 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF1938 PF09153.5 KNZ73346.1 - 0.093 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) Allexi_40kDa PF05549.6 KNZ73346.1 - 0.23 10.7 1.4 4.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein Transketolase_N PF00456.16 KNZ73347.1 - 1e-17 63.9 0.6 1.6e-16 60.0 0.4 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 KNZ73347.1 - 9.9e-09 35.1 0.0 2.6e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 KNZ73347.1 - 2.1e-06 27.3 0.2 4.8e-06 26.1 0.2 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.16 KNZ73347.1 - 0.0018 17.8 0.1 0.007 15.9 0.0 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 KNZ73347.1 - 0.087 11.5 0.0 0.18 10.4 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component UPF0270 PF06794.7 KNZ73347.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) Tubulin PF00091.20 KNZ73349.1 - 9.6e-62 208.6 0.0 1.4e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KNZ73349.1 - 1.1e-40 138.5 0.0 1.8e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KNZ73349.1 - 8.8e-07 28.9 0.0 3e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KNZ73349.1 - 0.0026 17.2 0.0 0.0062 16.0 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain ART PF01129.13 KNZ73349.1 - 0.0031 16.6 0.2 0.0051 15.9 0.1 1.2 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase DUF1479 PF07350.7 KNZ73350.1 - 2.9e-136 454.2 0.0 3.3e-136 454.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 KNZ73350.1 - 0.02 14.9 0.2 0.88 9.5 0.1 3.0 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Complex1_LYR PF05347.10 KNZ73351.1 - 1.1e-11 44.3 0.0 1.7e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KNZ73351.1 - 8e-10 38.7 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KNZ73351.1 - 1.7e-05 25.2 0.0 2.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Cyanate_lyase PF02560.9 KNZ73352.1 - 8e-34 115.0 0.0 1.5e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain zf-C2H2 PF00096.21 KNZ73352.1 - 0.0054 16.9 0.7 0.0054 16.9 0.5 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type Sigma70_r4_2 PF08281.7 KNZ73352.1 - 0.0074 15.7 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 zf-C2H2_4 PF13894.1 KNZ73352.1 - 0.07 13.4 0.7 0.07 13.4 0.5 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger F-box-like PF12937.2 KNZ73353.1 - 9e-07 28.5 0.4 4.1e-06 26.4 0.3 2.2 1 0 0 1 1 1 1 F-box-like PIF1 PF05970.9 KNZ73354.1 - 1.4e-08 34.1 0.0 2.8e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 KNZ73354.1 - 0.055 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain HgmA PF04209.8 KNZ73357.1 - 2.2e-153 510.6 0.0 2.5e-153 510.4 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase AAA PF00004.24 KNZ73358.1 - 1.6e-14 54.1 0.1 4.2e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.13 KNZ73358.1 - 3.9e-12 45.9 0.0 1.9e-11 43.7 0.0 2.1 3 0 0 3 3 3 1 BAH domain AAA_16 PF13191.1 KNZ73358.1 - 5.6e-10 39.4 0.0 5.9e-09 36.1 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KNZ73358.1 - 1.7e-07 31.4 0.0 4.5e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KNZ73358.1 - 0.00037 19.5 0.0 0.00068 18.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 KNZ73358.1 - 0.00069 19.3 0.9 0.0017 18.0 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 KNZ73358.1 - 0.0046 16.5 0.0 0.011 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KNZ73358.1 - 0.0097 15.5 0.0 0.087 12.4 0.0 2.4 2 1 0 2 2 2 1 NACHT domain NTPase_1 PF03266.10 KNZ73358.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 NTPase Arch_ATPase PF01637.13 KNZ73358.1 - 0.11 12.1 0.0 0.56 9.8 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase DUF4293 PF14126.1 KNZ73362.1 - 0.08 12.8 9.8 0.042 13.7 2.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Patatin PF01734.17 KNZ73364.1 - 2.9e-34 118.7 0.0 1.2e-33 116.8 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase Abhydrolase_6 PF12697.2 KNZ73365.1 - 1e-30 107.2 0.0 1.3e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ73365.1 - 9.7e-19 67.8 0.1 4.1e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ73365.1 - 5.3e-14 52.2 0.0 1e-13 51.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KNZ73365.1 - 9.4e-09 35.1 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 KNZ73365.1 - 2.8e-08 34.2 0.0 3.7e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 KNZ73365.1 - 3.6e-05 23.5 0.0 7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF676 PF05057.9 KNZ73365.1 - 6.7e-05 22.2 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KNZ73365.1 - 0.0014 18.2 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 KNZ73365.1 - 0.0042 16.5 0.1 0.42 10.0 0.0 2.2 1 1 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.15 KNZ73365.1 - 0.011 15.2 0.0 0.044 13.2 0.0 1.9 2 0 0 2 2 2 0 Putative esterase Chlorophyllase PF07224.6 KNZ73365.1 - 0.023 13.4 0.0 0.038 12.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 KNZ73365.1 - 0.041 12.7 0.0 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 KNZ73365.1 - 0.043 13.3 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2048 PF09752.4 KNZ73365.1 - 0.047 12.5 0.0 0.33 9.7 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF900 PF05990.7 KNZ73365.1 - 0.094 12.0 0.1 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Arv1 PF04161.8 KNZ73368.1 - 4.8e-24 85.4 8.0 8.3e-24 84.6 5.6 1.3 1 0 0 1 1 1 1 Arv1-like family Sigma_reg_N PF13800.1 KNZ73368.1 - 0.18 11.8 0.4 2.4 8.2 0.0 2.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF410 PF04190.8 KNZ73370.1 - 1.9e-31 109.5 0.0 2.4e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_16 PF13432.1 KNZ73370.1 - 0.048 14.3 0.1 19 6.0 0.0 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ73370.1 - 0.19 11.7 0.6 14 5.8 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Helitron_like_N PF14214.1 KNZ73372.1 - 3.2e-20 72.6 0.0 5.6e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ73372.1 - 0.022 14.3 0.3 0.057 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3296) PIF1 PF05970.9 KNZ73373.1 - 5.8e-13 48.5 0.0 6.1e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase MIP PF00230.15 KNZ73376.1 - 9.2e-46 156.1 13.7 1e-45 155.9 9.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4271 PF14093.1 KNZ73376.1 - 0.081 12.5 11.4 0.074 12.7 7.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) DUF423 PF04241.10 KNZ73376.1 - 0.21 11.5 7.7 0.049 13.5 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF423) HSBP1 PF06825.7 KNZ73377.1 - 1.3e-16 59.8 1.0 2e-16 59.3 0.7 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 ApoO PF09769.4 KNZ73377.1 - 0.02 14.6 0.2 0.025 14.3 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein O Lamp PF01299.12 KNZ73377.1 - 0.033 13.3 2.8 0.04 13.0 2.0 1.0 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) NPV_P10 PF05531.7 KNZ73377.1 - 0.038 14.2 0.5 0.079 13.2 0.3 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4164 PF13747.1 KNZ73377.1 - 0.05 13.7 0.2 0.07 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Matrilin_ccoil PF10393.4 KNZ73377.1 - 0.057 12.7 0.2 0.66 9.3 0.1 2.1 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Troponin-I_N PF11636.3 KNZ73377.1 - 0.067 12.8 1.7 0.067 12.8 1.2 2.1 2 0 0 2 2 2 0 Troponin I residues 1-32 DUF935 PF06074.7 KNZ73377.1 - 0.075 11.7 0.2 0.092 11.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Baculo_PEP_C PF04513.7 KNZ73377.1 - 0.083 12.7 0.1 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus GOLGA2L5 PF15070.1 KNZ73377.1 - 0.11 11.0 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Gti1_Pac2 PF09729.4 KNZ73378.1 - 4.7e-48 163.2 0.1 1.2e-47 161.8 0.0 1.7 2 0 0 2 2 2 1 Gti1/Pac2 family PDE8 PF08629.5 KNZ73378.1 - 3.1 7.6 5.8 5.7 6.8 0.6 3.2 2 1 1 3 3 3 0 PDE8 phosphodiesterase Ank PF00023.25 KNZ73379.1 - 1.5e-45 150.8 0.9 6.8e-11 41.4 0.0 6.0 5 1 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 KNZ73379.1 - 5.4e-43 145.2 0.5 9.4e-19 67.5 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNZ73379.1 - 3.9e-37 125.9 0.4 1.7e-13 50.6 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KNZ73379.1 - 1.3e-33 114.1 2.5 3.2e-09 36.7 0.0 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ73379.1 - 2.6e-33 110.7 0.1 2e-06 27.4 0.0 6.2 5 1 1 6 6 6 5 Ankyrin repeat Chromo PF00385.19 KNZ73380.1 - 0.00031 20.3 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KNZ73380.1 - 0.021 14.4 0.1 0.038 13.7 0.1 1.4 1 1 0 1 1 1 0 RNA binding activity-knot of a chromodomain COesterase PF00135.23 KNZ73381.1 - 4.5e-88 296.2 0.8 3.1e-86 290.2 0.6 2.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ73381.1 - 8.2e-12 45.1 0.1 3.2e-11 43.1 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 KNZ73381.1 - 0.0031 16.9 0.2 0.016 14.6 0.1 1.9 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KNZ73381.1 - 0.004 16.4 0.0 0.0075 15.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KNZ73381.1 - 0.036 13.8 0.1 0.064 13.0 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2424 PF10340.4 KNZ73381.1 - 0.069 11.7 0.1 0.47 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 KNZ73382.1 - 1.6e-26 93.6 0.0 2.3e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ73382.1 - 5.8e-09 35.8 0.0 1.5e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KNZ73382.1 - 5e-06 26.9 0.0 9.5e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 KNZ73382.1 - 2.9e-05 23.7 0.0 0.13 11.7 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KNZ73382.1 - 0.00024 20.9 0.0 0.00045 19.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 KNZ73382.1 - 0.00052 19.5 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 KNZ73382.1 - 0.0094 15.5 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.7 KNZ73382.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 KNZ73382.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S28 PF05577.7 KNZ73382.1 - 0.12 10.9 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_2 PF02230.11 KNZ73382.1 - 0.14 11.5 0.0 0.39 10.1 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase AAA PF00004.24 KNZ73383.1 - 5.3e-91 301.7 0.0 6.6e-48 162.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KNZ73383.1 - 4.2e-13 48.8 0.0 7e-06 25.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KNZ73383.1 - 2.5e-12 47.0 0.2 0.0039 17.3 0.0 5.1 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 KNZ73383.1 - 5.6e-12 46.0 1.4 0.00019 21.4 0.1 3.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KNZ73383.1 - 1.1e-10 42.3 0.0 2.3e-05 25.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KNZ73383.1 - 2.7e-10 40.2 0.0 0.00019 21.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KNZ73383.1 - 4e-10 39.5 1.3 0.00096 18.8 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KNZ73383.1 - 4.2e-10 39.7 0.0 0.00048 20.0 0.0 3.1 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 KNZ73383.1 - 1.4e-09 37.9 0.0 0.0021 17.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KNZ73383.1 - 2.6e-08 33.4 0.8 0.0052 16.5 0.0 3.8 3 1 0 3 3 2 2 Part of AAA domain AAA_28 PF13521.1 KNZ73383.1 - 5.6e-08 32.9 0.0 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KNZ73383.1 - 9e-08 31.5 0.2 0.013 14.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KNZ73383.1 - 9.3e-08 31.6 0.0 0.015 14.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 KNZ73383.1 - 1.4e-07 31.6 0.0 0.013 15.6 0.0 2.9 3 0 0 3 3 2 2 RNA helicase TIP49 PF06068.8 KNZ73383.1 - 2e-07 30.0 0.0 0.0047 15.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 KNZ73383.1 - 2.8e-07 30.1 2.2 1.3 8.3 0.0 4.3 3 1 1 4 4 4 2 AAA domain Zeta_toxin PF06414.7 KNZ73383.1 - 3.7e-07 29.4 0.0 0.012 14.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Sigma54_activ_2 PF14532.1 KNZ73383.1 - 8.3e-07 29.1 0.0 0.02 14.9 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain NACHT PF05729.7 KNZ73383.1 - 1.3e-06 28.1 0.4 0.26 10.9 0.0 3.9 3 1 1 4 4 4 2 NACHT domain AAA_18 PF13238.1 KNZ73383.1 - 1e-05 25.8 0.0 0.11 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 KNZ73383.1 - 2.4e-05 24.6 0.0 0.25 11.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.21 KNZ73383.1 - 2.5e-05 23.7 0.0 0.29 10.5 0.0 3.4 3 1 0 3 3 3 2 Sigma-54 interaction domain AAA_3 PF07726.6 KNZ73383.1 - 3.1e-05 23.6 0.0 0.11 12.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KNZ73383.1 - 3.4e-05 23.0 0.2 0.88 8.6 0.0 3.2 2 1 1 3 3 3 2 KaiC DUF815 PF05673.8 KNZ73383.1 - 0.00036 19.5 0.0 0.008 15.1 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF815) PhoH PF02562.11 KNZ73383.1 - 0.0004 19.6 0.2 0.82 8.8 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Viral_helicase1 PF01443.13 KNZ73383.1 - 0.0004 19.9 0.0 0.55 9.7 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 KNZ73383.1 - 0.00075 18.4 0.0 0.35 9.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 KNZ73383.1 - 0.0013 18.5 0.0 2.1 7.9 0.0 3.2 2 2 1 3 3 3 1 Archaeal ATPase Parvo_NS1 PF01057.12 KNZ73383.1 - 0.0014 17.5 0.0 1.3 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATP-synt_ab PF00006.20 KNZ73383.1 - 0.0016 17.9 0.0 0.38 10.2 0.0 2.7 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Cytidylate_kin2 PF13189.1 KNZ73383.1 - 0.0083 16.0 0.0 4 7.3 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_24 PF13479.1 KNZ73383.1 - 0.0089 15.6 0.1 1.8 8.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 KNZ73383.1 - 0.0093 15.8 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase NTPase_1 PF03266.10 KNZ73383.1 - 0.015 15.0 0.1 1.1 8.9 0.0 3.0 3 0 0 3 3 2 0 NTPase Rad17 PF03215.10 KNZ73383.1 - 0.017 13.8 0.0 3.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein UPF0079 PF02367.12 KNZ73383.1 - 0.018 14.6 0.5 5.7 6.5 0.0 2.6 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 KNZ73383.1 - 0.019 14.5 0.0 6.8 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 KNZ73383.1 - 0.04 13.7 0.0 10 5.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AFG1_ATPase PF03969.11 KNZ73383.1 - 0.058 12.1 0.0 2.4 6.8 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase DUF2075 PF09848.4 KNZ73383.1 - 0.12 11.3 0.0 13 4.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 KNZ73383.1 - 0.14 11.0 0.0 13 4.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KNZ73383.1 - 0.14 12.1 0.0 14 5.6 0.0 3.1 2 2 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 KNZ73383.1 - 0.14 11.6 0.0 10 5.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 KNZ73383.1 - 0.17 11.0 0.0 15 4.7 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Bac_DnaA PF00308.13 KNZ73383.1 - 0.19 11.3 0.0 3.9 7.0 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_10 PF12846.2 KNZ73383.1 - 0.28 10.6 0.7 30 3.9 0.0 3.0 4 0 0 4 4 3 0 AAA-like domain DUF829 PF05705.9 KNZ73384.1 - 1.8e-28 99.8 0.0 2.2e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 KNZ73384.1 - 0.0024 17.8 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glycos_transf_N PF04413.11 KNZ73384.1 - 0.06 12.4 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) UBN2_2 PF14227.1 KNZ73385.1 - 0.0026 17.3 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ73385.1 - 0.0058 16.4 0.1 0.26 11.0 0.0 2.1 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type Invas_SpaK PF03519.9 KNZ73385.1 - 0.035 13.9 0.2 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Invasion protein B family DUF1482 PF07358.6 KNZ73385.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) zf-CCHC PF00098.18 KNZ73386.1 - 0.026 14.4 0.6 0.051 13.5 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 KNZ73387.1 - 0.00059 19.9 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Ceramidase_alk PF04734.8 KNZ73390.1 - 1.3e-11 43.1 0.1 6.1e-10 37.6 0.1 2.0 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase PIF1 PF05970.9 KNZ73391.1 - 1.6e-33 116.1 0.0 2e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 KNZ73391.1 - 1.1e-07 30.0 0.0 1.4e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ73391.1 - 6.1e-05 23.1 0.0 0.00013 22.0 0.0 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain DKCLD PF08068.7 KNZ73392.1 - 1e-30 105.4 0.1 3.8e-30 103.5 0.1 2.0 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 KNZ73392.1 - 2e-24 86.4 0.2 6.5e-21 75.0 0.1 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KNZ73392.1 - 4.9e-21 74.2 1.7 1.2e-20 72.9 1.1 1.7 1 0 0 1 1 1 1 PUA domain Ribosomal_L22e PF01776.12 KNZ73393.1 - 7e-48 161.2 0.2 7.9e-48 161.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF2660 PF10859.3 KNZ73393.1 - 0.1 12.8 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) HA2 PF04408.18 KNZ73394.1 - 3.9e-20 71.7 0.6 1.3e-19 70.1 0.1 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KNZ73394.1 - 8.6e-14 51.1 0.1 2e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KNZ73394.1 - 1.4e-11 44.2 0.0 4.8e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KNZ73394.1 - 3.8e-08 33.5 1.2 1e-07 32.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 KNZ73394.1 - 4.7e-07 29.4 0.0 8.7e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ABC_tran PF00005.22 KNZ73394.1 - 0.013 15.8 0.5 0.061 13.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter KaiC PF06745.8 KNZ73394.1 - 0.021 13.9 0.3 0.11 11.5 0.0 2.1 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.17 KNZ73394.1 - 0.023 13.5 0.0 0.076 11.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.1 KNZ73394.1 - 0.04 13.4 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L22 PF00237.14 KNZ73394.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e SNF2_N PF00176.18 KNZ73395.1 - 8.5e-56 188.9 4.8 3.5e-53 180.3 1.5 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain DBINO PF13892.1 KNZ73395.1 - 1.6e-49 167.5 19.2 1.6e-49 167.5 13.3 2.2 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.26 KNZ73395.1 - 8.7e-13 47.9 0.0 2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KNZ73395.1 - 1e-07 31.0 0.0 2e-05 23.5 0.0 2.8 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 Lyase_1 PF00206.15 KNZ73396.1 - 1.3e-103 346.4 0.0 1.6e-103 346.1 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KNZ73396.1 - 5.5e-13 48.7 0.0 1.3e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus PEX11 PF05648.9 KNZ73397.1 - 2.7e-50 170.7 0.6 3e-50 170.5 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Cmc1 PF08583.5 KNZ73398.1 - 9.7e-13 47.7 1.2 1.2e-12 47.4 0.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Radical_SAM PF04055.16 KNZ73399.1 - 5.2e-14 52.7 0.0 9.7e-14 51.8 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Ribosomal_S28e PF01200.13 KNZ73400.1 - 7.7e-30 102.4 1.9 9.1e-30 102.2 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Glyco_transf_8 PF01501.15 KNZ73401.1 - 6e-27 94.5 0.0 7.9e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Peptidase_M22 PF00814.20 KNZ73402.1 - 5.2e-77 258.9 0.0 1e-76 257.9 0.0 1.5 1 0 0 1 1 1 1 Glycoprotease family 2-oxoacid_dh PF00198.18 KNZ73403.1 - 1.3e-68 230.7 0.1 1.9e-36 125.5 0.0 2.1 1 1 1 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KNZ73403.1 - 1.7e-17 62.7 1.5 4.2e-17 61.5 1.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KNZ73403.1 - 1.6e-14 53.2 0.2 3.1e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 e3 binding domain PE PF00934.15 KNZ73403.1 - 0.024 14.6 0.1 0.091 12.8 0.0 1.9 2 0 0 2 2 2 0 PE family EXOSC1 PF10447.4 KNZ73404.1 - 2e-20 72.5 0.0 3.7e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KNZ73404.1 - 0.023 13.9 0.1 0.091 12.0 0.0 2.0 1 1 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region Es2 PF09751.4 KNZ73405.1 - 2.6e-53 181.9 6.9 2.6e-53 181.9 4.8 3.6 3 1 1 4 4 4 1 Nuclear protein Es2 NUDE_C PF04880.8 KNZ73405.1 - 0.0045 17.3 30.7 0.0045 17.3 21.3 5.6 4 2 0 4 4 4 1 NUDE protein, C-terminal conserved region Flg_hook PF02120.11 KNZ73405.1 - 0.02 14.5 8.7 0.032 13.9 0.8 3.3 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK ATG16 PF08614.6 KNZ73405.1 - 0.099 12.4 28.3 0.57 9.9 10.9 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) YiiD_Cterm PF09500.5 KNZ73405.1 - 0.15 11.6 0.4 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Putative thioesterase (yiiD_Cterm) Nefa_Nip30_N PF10187.4 KNZ73406.1 - 9.5e-18 64.2 8.7 1.5e-17 63.5 6.0 1.3 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.8 KNZ73406.1 - 0.013 14.6 8.8 0.015 14.4 6.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SLX9 PF15341.1 KNZ73408.1 - 3e-22 79.3 4.6 4.4e-22 78.7 3.2 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 EamA PF00892.15 KNZ73408.1 - 7e-07 29.3 9.3 7e-07 29.3 6.5 3.7 3 1 0 3 3 3 1 EamA-like transporter family DUF914 PF06027.7 KNZ73408.1 - 1.8e-05 23.7 20.4 0.0001 21.3 11.6 2.2 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 KNZ73408.1 - 6.4e-05 23.1 4.9 6.4e-05 23.1 3.4 3.7 3 1 0 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 KNZ73408.1 - 0.003 16.5 8.0 0.0054 15.6 5.5 1.7 1 1 0 1 1 1 1 UAA transporter family SURF6 PF04935.7 KNZ73408.1 - 0.2 10.9 3.1 0.28 10.4 2.2 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 Bap31 PF05529.7 KNZ73408.1 - 0.59 9.5 2.8 0.51 9.7 0.1 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Ank_2 PF12796.2 KNZ73409.1 - 3e-20 72.3 0.5 3e-15 56.3 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ73409.1 - 4.5e-15 54.6 0.3 1e-08 34.5 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KNZ73409.1 - 1.7e-14 53.8 1.6 9.8e-07 29.1 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ73409.1 - 1e-13 50.0 0.4 6.6e-06 25.8 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KNZ73409.1 - 1.8e-12 47.0 1.7 2.7e-08 33.7 0.3 3.2 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Macoilin PF09726.4 KNZ73410.1 - 9.7e-05 20.8 20.2 9.7e-05 20.8 14.0 2.7 1 1 1 2 2 2 1 Transmembrane protein FLO_LFY PF01698.11 KNZ73410.1 - 0.02 13.7 1.1 0.044 12.6 0.8 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein ATG16 PF08614.6 KNZ73410.1 - 0.34 10.6 29.5 3.3 7.4 4.3 3.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Cep57_CLD_2 PF14197.1 KNZ73410.1 - 0.91 9.5 24.3 0.044 13.7 6.1 4.4 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 DUF342 PF03961.8 KNZ73410.1 - 2.9 6.1 12.2 0.13 10.6 4.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF972 PF06156.8 KNZ73410.1 - 3.7 7.9 20.0 14 6.0 0.1 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF972) TSC22 PF01166.13 KNZ73410.1 - 4.5 7.3 10.9 6.3 6.8 0.3 3.8 3 1 0 3 3 3 0 TSC-22/dip/bun family AAA_19 PF13245.1 KNZ73411.1 - 0.00087 18.9 0.0 0.0026 17.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RecA PF00154.16 KNZ73411.1 - 0.0017 17.4 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.6 KNZ73411.1 - 0.0021 16.9 0.0 0.012 14.5 0.0 2.0 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KNZ73411.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain PPR_2 PF13041.1 KNZ73412.1 - 7.2e-35 118.7 0.1 4.1e-10 39.4 0.0 7.0 4 3 3 7 7 7 6 PPR repeat family PPR_1 PF12854.2 KNZ73412.1 - 7.7e-22 76.4 3.9 3.5e-09 35.9 0.0 6.7 8 0 0 8 8 8 3 PPR repeat PPR_3 PF13812.1 KNZ73412.1 - 7.4e-19 66.3 2.3 1.6e-05 24.8 0.0 8.4 9 0 0 9 9 9 3 Pentatricopeptide repeat domain PPR PF01535.15 KNZ73412.1 - 8.3e-19 66.1 8.6 2.4e-07 30.2 0.0 6.7 7 0 0 7 7 7 4 PPR repeat TPR_14 PF13428.1 KNZ73412.1 - 0.00071 19.9 0.2 2 9.3 0.0 5.3 4 2 2 6 6 6 1 Tetratricopeptide repeat FGF-BP1 PF06473.7 KNZ73412.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Hap4_Hap_bind PF10297.4 KNZ73413.1 - 1e-06 28.3 3.5 2.4e-06 27.1 2.4 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 KNZ73413.1 - 1.3e-05 25.0 17.1 5.8e-05 22.9 4.7 2.3 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 KNZ73413.1 - 0.00099 18.8 13.0 0.0056 16.4 1.7 2.3 2 0 0 2 2 2 2 Basic region leucine zipper TSC22 PF01166.13 KNZ73413.1 - 3.6 7.6 5.2 24 5.0 1.1 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family Sugar_tr PF00083.19 KNZ73414.1 - 7.7e-39 133.5 28.4 1e-37 129.8 19.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ73414.1 - 1.5e-16 60.0 43.3 5.7e-09 35.1 14.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily GRIP PF01465.15 KNZ73419.1 - 0.069 12.6 0.3 0.78 9.2 0.0 2.2 2 0 0 2 2 2 0 GRIP domain Glyco_hydro_3_C PF01915.17 KNZ73420.1 - 1.7e-41 142.1 0.2 4.2e-31 108.2 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 KNZ73420.1 - 3.3e-37 128.0 0.0 4.4e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 KNZ73420.1 - 0.0007 19.4 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3445 PF11927.3 KNZ73421.1 - 8.3e-61 205.5 0.0 1.5e-60 204.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3445) Mt_ATP-synt_D PF05873.7 KNZ73422.1 - 1.5e-12 47.4 0.6 1.9e-12 47.1 0.4 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF2408 PF10303.4 KNZ73422.1 - 0.061 13.4 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) CbiC PF02570.10 KNZ73422.1 - 0.12 11.7 0.2 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Precorrin-8X methylmutase Glyco_hydro_35 PF01301.14 KNZ73423.1 - 8.3e-82 275.0 0.3 1.3e-81 274.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 KNZ73423.1 - 3.7e-49 165.6 6.4 1.3e-25 89.8 0.3 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 KNZ73423.1 - 4.4e-41 140.2 1.0 9.9e-41 139.0 0.7 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 KNZ73423.1 - 1.8e-21 75.2 0.0 4.9e-21 73.9 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 A_deamin PF02137.13 KNZ73424.1 - 1e-58 199.3 0.0 1.3e-58 198.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Herpes_Helicase PF02689.9 KNZ73428.1 - 2.4e-07 28.9 0.0 2.5e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Helicase Pex24p PF06398.6 KNZ73429.1 - 3.4e-07 29.4 1.5 5e-07 28.8 1.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin CRPV_capsid PF08762.5 KNZ73429.1 - 0.077 12.4 0.1 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 CRPV capsid protein like Rad21_Rec8_N PF04825.8 KNZ73429.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein HA2 PF04408.18 KNZ73430.1 - 1.8e-17 63.2 0.0 4.4e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KNZ73430.1 - 8.7e-12 44.7 0.0 2e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 KNZ73430.1 - 2.8e-09 37.4 0.0 0.00015 22.3 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.24 KNZ73430.1 - 3.5e-08 33.1 0.0 7.4e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 KNZ73430.1 - 2.5e-05 24.0 0.0 0.00022 21.0 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ResIII PF04851.10 KNZ73430.1 - 0.037 13.8 0.1 0.9 9.3 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Adaptin_N PF01602.15 KNZ73431.1 - 4e-122 408.2 6.3 5.5e-122 407.7 4.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KNZ73431.1 - 4.5e-38 129.6 0.0 1.1e-37 128.4 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KNZ73431.1 - 5.5e-19 68.5 0.0 1.3e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain RasGAP PF00616.14 KNZ73432.1 - 3.1e-36 124.8 0.0 4.9e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KNZ73432.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 C2 domain ELO PF01151.13 KNZ73433.1 - 4.6e-59 199.7 17.4 5.3e-59 199.5 12.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GFO_IDH_MocA_C PF02894.12 KNZ73433.1 - 0.049 13.4 0.1 0.094 12.5 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain DPM3 PF08285.6 KNZ73433.1 - 0.89 9.4 7.6 4.8 7.0 2.0 3.0 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) SNARE_assoc PF09335.6 KNZ73433.1 - 4.4 7.5 12.5 8.9 6.5 0.8 3.0 3 0 0 3 3 3 0 SNARE associated Golgi protein DIE2_ALG10 PF04922.7 KNZ73434.1 - 0.0047 16.0 1.1 0.0058 15.7 0.8 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Asp_protease_2 PF13650.1 KNZ73435.1 - 0.0046 17.4 0.0 0.005 17.3 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease DUF1162 PF06650.7 KNZ73436.1 - 2.1e-54 184.5 0.0 1.8e-52 178.2 0.0 3.6 4 1 0 4 4 4 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KNZ73436.1 - 3.1e-29 100.9 0.2 7.9e-29 99.5 0.1 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KNZ73436.1 - 8.1e-06 25.9 0.0 2.5e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain DENN PF02141.16 KNZ73437.1 - 3.5e-19 69.2 0.0 1.4e-18 67.3 0.0 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain OmpH PF03938.9 KNZ73437.1 - 0.14 12.0 10.2 0.3 11.0 7.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 KNZ73437.1 - 0.22 11.0 9.9 0.61 9.6 6.8 1.7 1 0 0 1 1 1 0 IncA protein ADIP PF11559.3 KNZ73437.1 - 0.41 10.5 16.0 0.035 13.9 7.0 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 KNZ73437.1 - 0.52 9.2 9.4 1.1 8.2 6.5 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Tup_N PF08581.5 KNZ73437.1 - 0.96 9.6 9.7 0.22 11.7 3.7 2.1 2 0 0 2 2 2 0 Tup N-terminal DUF342 PF03961.8 KNZ73437.1 - 1.9 6.8 9.2 3.8 5.8 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 KNZ73437.1 - 4.3 7.7 13.9 6.7 7.1 0.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Mg_trans_NIPA PF05653.9 KNZ73438.1 - 1.6e-20 73.2 14.1 6.7e-11 41.6 0.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 KNZ73438.1 - 0.0017 18.4 5.1 0.0017 18.4 3.6 3.3 3 0 0 3 3 3 1 EamA-like transporter family PufQ PF05398.6 KNZ73438.1 - 0.14 12.1 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 PufQ cytochrome subunit DUF423 PF04241.10 KNZ73438.1 - 9.4 6.2 10.6 18 5.3 0.4 4.2 3 2 2 5 5 5 0 Protein of unknown function (DUF423) AAA_2 PF07724.9 KNZ73439.1 - 1.8e-50 171.1 0.0 1.1e-45 155.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 KNZ73439.1 - 4.6e-25 88.3 0.0 8.6e-14 51.8 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KNZ73439.1 - 4.1e-21 74.6 0.2 2.2e-20 72.3 0.1 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 KNZ73439.1 - 3.9e-14 52.3 3.3 7e-11 41.8 0.2 4.3 4 0 0 4 4 3 1 Clp amino terminal domain AAA_5 PF07728.9 KNZ73439.1 - 4.6e-14 52.3 0.1 6.6e-07 29.1 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KNZ73439.1 - 2.5e-13 50.4 0.2 9.5e-05 22.4 0.0 4.9 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 KNZ73439.1 - 1.1e-09 38.4 0.1 0.0015 18.6 0.0 3.9 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.12 KNZ73439.1 - 2.4e-08 33.5 0.0 0.00043 19.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.21 KNZ73439.1 - 4.5e-08 32.7 0.0 5.1e-05 22.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.1 KNZ73439.1 - 2.8e-07 30.8 0.1 0.0021 18.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KNZ73439.1 - 8.1e-07 28.4 0.3 0.0023 17.1 0.0 3.1 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KNZ73439.1 - 4.9e-06 26.2 0.1 0.1 12.3 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 KNZ73439.1 - 8e-06 25.0 0.0 0.0027 16.8 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_17 PF13207.1 KNZ73439.1 - 8e-06 26.6 8.1 0.092 13.5 3.2 4.2 3 1 0 3 3 2 2 AAA domain TIP49 PF06068.8 KNZ73439.1 - 1.3e-05 24.1 2.6 0.035 12.8 0.0 3.5 3 1 1 4 4 4 2 TIP49 C-terminus AAA_24 PF13479.1 KNZ73439.1 - 2.6e-05 23.9 0.0 0.034 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KNZ73439.1 - 8.3e-05 22.2 0.0 0.21 11.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.17 KNZ73439.1 - 0.00011 22.2 0.3 0.79 9.9 0.0 2.8 3 0 0 3 3 2 2 RNA helicase AAA_33 PF13671.1 KNZ73439.1 - 0.00022 21.1 0.0 0.14 12.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KNZ73439.1 - 0.00058 18.9 0.0 0.86 8.5 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 KNZ73439.1 - 0.0012 19.1 1.7 0.97 9.7 0.0 3.5 3 0 0 3 3 3 1 ABC transporter AAA_28 PF13521.1 KNZ73439.1 - 0.0013 18.7 1.0 0.89 9.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain Torsin PF06309.6 KNZ73439.1 - 0.0014 18.4 0.2 0.041 13.7 0.0 2.9 4 0 0 4 4 2 1 Torsin PhoH PF02562.11 KNZ73439.1 - 0.0015 17.7 0.0 0.24 10.5 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_23 PF13476.1 KNZ73439.1 - 0.0022 18.3 7.8 3.1 8.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KNZ73439.1 - 0.003 16.9 1.2 3.5 6.9 0.0 3.5 3 1 1 4 4 3 0 AAA domain HrpB4 PF09502.5 KNZ73439.1 - 0.0073 15.5 0.1 0.015 14.5 0.1 1.4 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB4) T2SE PF00437.15 KNZ73439.1 - 0.0086 15.0 0.3 0.085 11.7 0.0 2.4 3 0 0 3 3 2 1 Type II/IV secretion system protein Laminin_II PF06009.7 KNZ73439.1 - 0.011 15.5 1.4 0.027 14.2 1.0 1.7 1 0 0 1 1 1 0 Laminin Domain II MobB PF03205.9 KNZ73439.1 - 0.016 14.8 0.0 2.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KNZ73439.1 - 0.017 14.6 0.0 5.1 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain IncA PF04156.9 KNZ73439.1 - 0.024 14.2 9.1 0.051 13.1 6.3 1.5 1 0 0 1 1 1 0 IncA protein DUF2075 PF09848.4 KNZ73439.1 - 0.025 13.5 0.0 3.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 KNZ73439.1 - 0.03 13.9 0.0 8.8 5.9 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KNZ73439.1 - 0.03 13.5 0.0 2.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 CbiA PF01656.18 KNZ73439.1 - 0.035 13.5 0.0 6.3 6.1 0.0 2.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_3 PF07726.6 KNZ73439.1 - 0.046 13.3 0.0 31 4.1 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) EcoEI_R_C PF08463.5 KNZ73439.1 - 0.051 13.4 4.6 1 9.2 2.8 3.0 3 0 0 3 3 3 0 EcoEI R protein C-terminal APS_kinase PF01583.15 KNZ73439.1 - 0.062 12.9 0.0 1.7 8.2 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase Sigma54_activ_2 PF14532.1 KNZ73439.1 - 0.068 13.2 0.0 21 5.1 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 KNZ73439.1 - 0.087 12.5 0.7 6.1 6.5 0.0 3.4 4 0 0 4 4 3 0 NTPase AAA_10 PF12846.2 KNZ73439.1 - 0.18 11.2 5.6 3.4 7.0 0.0 4.2 3 2 1 5 5 4 0 AAA-like domain KaiC PF06745.8 KNZ73439.1 - 0.26 10.3 4.0 4.8 6.2 0.0 3.8 3 1 1 4 4 4 0 KaiC AAA_13 PF13166.1 KNZ73439.1 - 1.6 7.0 8.9 3 6.1 6.2 1.4 1 0 0 1 1 1 0 AAA domain Pox_A_type_inc PF04508.7 KNZ73439.1 - 8.2 6.5 17.2 0.5 10.2 1.1 4.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat INCENP_ARK-bind PF03941.10 KNZ73440.1 - 2.5e-17 62.4 1.6 3.6e-17 61.9 0.3 2.1 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Mnd1 PF03962.10 KNZ73440.1 - 2.2 7.9 14.9 6.6 6.3 10.3 1.8 1 0 0 1 1 1 0 Mnd1 family DCP2 PF05026.8 KNZ73441.1 - 3.3e-36 123.0 1.6 7.8e-36 121.8 1.1 1.7 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KNZ73441.1 - 8.8e-07 28.6 0.0 0.0036 16.9 0.0 2.3 2 0 0 2 2 2 2 NUDIX domain PARP PF00644.15 KNZ73442.1 - 1.5e-10 40.9 0.0 4.1e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 KNZ73442.1 - 0.0032 16.8 0.0 0.0077 15.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Dot_icm_IcmQ PF09475.5 KNZ73442.1 - 0.078 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) zf-CHCC PF10276.4 KNZ73444.1 - 5.9e-11 42.0 0.7 9.4e-11 41.3 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger domain Pkinase PF00069.20 KNZ73445.1 - 1e-56 191.9 0.0 2.4e-56 190.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73445.1 - 6.1e-23 81.2 0.0 1.4e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2956 PF11169.3 KNZ73445.1 - 0.11 12.4 5.0 0.24 11.3 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Pribosyltran_N PF13793.1 KNZ73446.1 - 4.4e-45 152.1 0.9 3e-43 146.2 0.1 2.5 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KNZ73446.1 - 1.6e-37 129.0 4.3 1.6e-32 112.7 0.7 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KNZ73446.1 - 9.2e-13 48.0 0.4 6.5e-12 45.2 0.1 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KNZ73446.1 - 0.00022 20.4 0.2 0.00041 19.6 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ECH PF00378.15 KNZ73447.1 - 2.5e-35 121.7 0.0 3e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HSCB_C PF07743.8 KNZ73449.1 - 4.1e-13 49.6 2.7 4.1e-13 49.5 1.0 1.6 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KNZ73449.1 - 2.6e-09 36.6 0.0 8.2e-09 35.0 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain zf-ribbon_3 PF13248.1 KNZ73449.1 - 2.3 7.5 5.7 2.2 7.6 3.0 1.6 2 0 0 2 2 2 0 zinc-ribbon domain AMP-binding PF00501.23 KNZ73451.1 - 2.9e-60 203.8 0.4 1.8e-37 128.7 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KNZ73451.1 - 3.4e-19 69.5 0.2 8.7e-19 68.2 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GYF PF02213.11 KNZ73452.1 - 3.2e-12 45.8 0.0 6.6e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 GYF domain Drc1-Sld2 PF11719.3 KNZ73452.1 - 0.13 11.2 1.6 0.19 10.7 1.1 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein FAD-oxidase_C PF02913.14 KNZ73453.1 - 2.5e-53 180.9 0.0 3.3e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KNZ73453.1 - 1.3e-35 121.8 0.2 2.5e-35 120.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Methyltransf_14 PF08484.6 KNZ73453.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Myb_DNA-bind_2 PF08914.6 KNZ73454.1 - 2.4e-08 33.6 1.1 7.5e-08 32.0 0.7 1.9 1 1 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 KNZ73454.1 - 0.057 13.9 4.4 0.22 12.0 1.1 2.9 2 1 0 2 2 2 0 Rap1, DNA-binding Pkinase PF00069.20 KNZ73455.1 - 1.2e-52 178.6 0.0 1.3e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73455.1 - 2.8e-19 69.2 0.0 3.8e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ73455.1 - 1.6e-05 24.0 0.1 2.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KNZ73455.1 - 0.007 15.7 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 RIO1 family TTL PF03133.10 KNZ73456.1 - 7.2e-48 163.0 0.0 9.4e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 KNZ73456.1 - 0.00087 19.0 0.0 0.0033 17.2 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain DUF2404 PF10296.4 KNZ73457.1 - 0.00038 20.5 0.0 0.0009 19.3 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) RNA_pol_Rpb8 PF03870.10 KNZ73459.1 - 1.2e-40 138.9 0.1 1.2e-39 135.6 0.1 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb8 Sec7 PF01369.15 KNZ73460.1 - 5e-38 130.6 0.0 7.9e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KNZ73460.1 - 4.2e-10 39.8 0.1 8.5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KNZ73460.1 - 2.6e-07 30.8 0.1 5.7e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 PH domain Pescadillo_N PF06732.6 KNZ73461.1 - 1.5e-116 388.6 0.0 1.5e-116 388.6 0.0 2.8 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 KNZ73461.1 - 4.2e-08 33.2 0.0 8.8e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_mis_repair PF01119.14 KNZ73461.1 - 0.008 15.6 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Nucleoplasmin PF03066.10 KNZ73461.1 - 0.056 12.9 9.7 0.013 14.9 2.8 2.5 2 0 0 2 2 2 0 Nucleoplasmin eIF-3c_N PF05470.7 KNZ73461.1 - 2.9 5.8 17.0 5.7 4.9 11.8 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus LSM PF01423.17 KNZ73462.1 - 1.2e-05 24.7 0.3 3.5e-05 23.2 0.2 1.9 1 1 0 1 1 1 1 LSM domain YkyB PF14177.1 KNZ73462.1 - 0.097 12.8 0.9 0.86 9.7 0.1 2.0 1 1 1 2 2 2 0 YkyB-like protein RdRP PF05183.7 KNZ73463.1 - 3.7e-142 475.0 0.0 5.1e-142 474.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase TrbC_Ftype PF09673.5 KNZ73463.1 - 0.13 11.8 0.0 0.35 10.5 0.0 1.7 1 1 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Complex1_LYR PF05347.10 KNZ73464.1 - 3.3e-08 33.2 0.0 4.3e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KNZ73464.1 - 9.7e-07 28.9 0.0 1.2e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Cyclin_N PF00134.18 KNZ73466.1 - 4.1e-37 126.5 1.9 5.7e-37 126.1 0.4 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KNZ73466.1 - 1.9e-09 37.4 0.1 4.3e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain GFO_IDH_MocA PF01408.17 KNZ73467.1 - 2.5e-09 37.7 0.4 1.1e-08 35.6 0.3 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold WAC_Acf1_DNA_bd PF10537.4 KNZ73469.1 - 4.9e-34 116.5 1.1 1.7e-33 114.8 0.7 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KNZ73469.1 - 4.5e-13 48.7 0.1 1.3e-12 47.2 0.1 1.8 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.1 KNZ73469.1 - 4.2e-06 26.4 0.0 1.1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 KNZ73469.1 - 0.00014 21.6 0.2 0.00051 19.8 0.1 2.1 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 2 Aa_trans PF01490.13 KNZ73470.1 - 4.2e-55 186.8 27.8 5.1e-55 186.6 19.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KNZ73470.1 - 0.00038 19.3 12.2 0.00038 19.3 8.5 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family PCI_Csn8 PF10075.4 KNZ73471.1 - 5.4e-21 74.8 0.0 8.7e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KNZ73471.1 - 6.8e-20 71.5 0.1 9.3e-20 71.0 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF592 PF04574.8 KNZ73471.1 - 0.041 13.4 0.0 6 6.4 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF592) DUF3299 PF11736.3 KNZ73471.1 - 0.19 11.6 0.6 0.33 10.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) WD40 PF00400.27 KNZ73472.1 - 9.4e-59 193.3 16.9 2.1e-12 46.3 0.2 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KNZ73472.1 - 2e-10 40.7 0.0 1.7e-05 24.6 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 KNZ73472.1 - 0.00032 19.6 0.1 0.0019 17.0 0.0 2.0 1 1 1 2 2 2 1 Coatomer WD associated region Nup160 PF11715.3 KNZ73472.1 - 0.0075 14.4 3.4 4.3 5.3 0.0 4.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KNZ73472.1 - 0.012 14.3 4.8 3.1 6.4 0.5 3.4 1 1 1 3 3 3 0 Nup133 N terminal like IKI3 PF04762.7 KNZ73472.1 - 0.017 12.9 0.3 0.1 10.4 0.0 2.1 2 1 1 3 3 3 0 IKI3 family DUF4221 PF13970.1 KNZ73472.1 - 0.017 14.4 0.0 4.6 6.4 0.0 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4221) Kelch_6 PF13964.1 KNZ73472.1 - 0.017 15.2 1.2 0.27 11.4 0.0 3.3 4 0 0 4 4 4 0 Kelch motif PQQ_2 PF13360.1 KNZ73472.1 - 0.035 13.5 0.4 7 6.0 0.0 2.8 2 1 0 2 2 2 0 PQQ-like domain ubiquitin PF00240.18 KNZ73473.1 - 9.8e-138 447.7 21.2 5.2e-34 115.4 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 KNZ73473.1 - 6.7e-78 256.3 20.9 5.8e-19 67.5 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KNZ73473.1 - 1.6e-24 85.9 9.4 0.00017 21.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KNZ73473.1 - 2.4e-21 76.0 0.6 0.0014 18.3 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KNZ73473.1 - 3.7e-14 52.5 2.9 0.12 12.3 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KNZ73473.1 - 1.1e-13 51.2 1.7 0.15 12.2 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KNZ73473.1 - 1.1e-10 41.3 0.0 1.5 8.8 0.0 4.8 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 KNZ73473.1 - 2e-07 30.6 4.9 3.5 7.4 0.0 4.3 4 0 0 4 4 4 4 FlgD Ig-like domain Methyltrans_RNA PF04452.9 KNZ73473.1 - 8.7e-07 28.2 0.6 1 8.4 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase TUG-UBL1 PF11470.3 KNZ73473.1 - 3.1e-06 27.0 4.8 6.4 6.7 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG ACT_4 PF13291.1 KNZ73473.1 - 0.00081 19.6 1.2 72 3.8 0.0 4.2 4 0 0 4 4 4 0 ACT domain Big_3_3 PF13750.1 KNZ73473.1 - 0.0014 18.0 0.0 50 3.2 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 KNZ73473.1 - 0.0033 15.8 13.1 3.9 5.6 0.2 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain DUF3861 PF12977.2 KNZ73473.1 - 0.012 15.6 5.3 65 3.7 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 KNZ73473.1 - 0.022 14.6 13.9 8.8 6.3 0.2 4.6 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 KNZ73473.1 - 0.027 14.4 29.1 3.5 7.7 1.2 4.3 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 KNZ73473.1 - 0.045 13.7 7.0 53 3.9 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 KNZ73473.1 - 1.4 9.0 12.6 86 3.2 0.1 5.8 4 4 0 4 4 4 0 FERM N-terminal domain CDC48_2 PF02933.12 KNZ73473.1 - 1.6 8.4 13.0 40 3.9 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 DUF3781 PF12636.2 KNZ73473.1 - 2.2 8.2 7.0 1.7e+02 2.2 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Fcf1 PF04900.7 KNZ73474.1 - 6.6e-29 99.9 0.8 1.8e-28 98.6 0.0 1.9 2 0 0 2 2 2 1 Fcf1 DUF2681 PF10883.3 KNZ73474.1 - 0.52 10.5 2.9 1 9.5 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF2012 PF09430.5 KNZ73475.1 - 3.1e-22 78.7 0.0 4.6e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 KNZ73475.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KNZ73475.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4480) CAP PF00188.21 KNZ73477.1 - 3.8e-22 79.0 1.7 6.9e-22 78.2 1.2 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family XRCC4 PF06632.7 KNZ73477.1 - 0.045 12.6 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Cortexin PF11057.3 KNZ73478.1 - 0.1 12.2 0.1 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Cortexin of kidney FAD_binding_6 PF00970.19 KNZ73479.1 - 4.5e-32 110.1 0.0 7e-32 109.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KNZ73479.1 - 1.4e-27 96.3 0.0 2.3e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KNZ73479.1 - 6.1e-06 26.2 0.0 7.1e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KNZ73479.1 - 0.0044 16.9 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DSPc PF00782.15 KNZ73480.1 - 5.4e-19 68.0 0.0 2.3e-17 62.8 0.0 2.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PNMA PF14893.1 KNZ73480.1 - 0.0052 15.8 0.5 0.0077 15.2 0.3 1.1 1 0 0 1 1 1 1 PNMA Y_phosphatase PF00102.22 KNZ73480.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KNZ73480.1 - 0.19 11.7 0.4 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF846 PF05832.7 KNZ73481.1 - 6.3e-53 178.3 6.5 7.9e-53 177.9 4.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) LRR_4 PF12799.2 KNZ73483.1 - 3.3e-11 42.5 4.3 0.021 14.4 0.2 6.5 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNZ73483.1 - 9.4e-08 31.7 9.6 0.018 14.7 0.4 4.8 5 1 1 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 KNZ73483.1 - 2.7e-06 26.8 11.3 5.8 7.3 0.0 8.8 9 0 0 9 9 9 2 Leucine Rich repeat Mem_trans PF03547.13 KNZ73483.1 - 0.0077 14.5 0.2 0.011 14.0 0.1 1.2 1 0 0 1 1 1 1 Membrane transport protein BNR PF02012.15 KNZ73484.1 - 2.2e-09 35.6 14.7 0.52 10.3 0.4 7.8 7 0 0 7 7 7 6 BNR/Asp-box repeat LBR_tudor PF09465.5 KNZ73486.1 - 0.046 13.3 0.1 0.097 12.3 0.1 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain gag-asp_proteas PF13975.1 KNZ73487.1 - 0.00012 21.8 0.0 0.00027 20.6 0.0 1.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ73487.1 - 0.0027 18.1 0.0 0.01 16.3 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.6 KNZ73487.1 - 0.027 14.3 0.0 2.4 8.0 0.0 2.4 3 0 0 3 3 3 0 Retroviral aspartyl protease AA_permease PF00324.16 KNZ73488.1 - 1.5e-118 396.1 34.3 1.9e-118 395.8 23.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KNZ73488.1 - 8.9e-33 113.4 37.4 1.1e-32 113.1 25.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KNZ73489.1 - 8.9e-119 396.9 37.6 1.1e-118 396.6 26.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KNZ73489.1 - 1e-33 116.5 37.5 1.3e-33 116.2 26.0 1.1 1 0 0 1 1 1 1 Amino acid permease RhoGEF PF00621.15 KNZ73490.1 - 1.7e-43 148.6 0.0 2.8e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 KNZ73490.1 - 3.5e-07 29.6 0.6 0.025 14.1 0.2 3.2 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNZ73490.1 - 3.9e-05 23.3 0.7 0.0043 16.7 0.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KNZ73490.1 - 0.067 13.2 0.3 7.5 7.0 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat PAXNEB PF05625.6 KNZ73491.1 - 6.9e-51 173.1 0.0 2.5e-50 171.3 0.0 1.7 1 1 0 1 1 1 1 PAXNEB protein Peptidase_S26 PF10502.4 KNZ73492.1 - 2.6e-08 33.4 0.0 2.6e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 KNZ73492.1 - 3.8e-06 26.4 0.0 7.2e-06 25.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase S24-like TPR_11 PF13414.1 KNZ73493.1 - 1.2e-10 40.8 3.0 3.4e-05 23.4 0.6 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KNZ73493.1 - 2.1e-06 27.0 1.7 0.021 14.4 0.1 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ73493.1 - 6.5e-05 22.5 1.3 0.53 10.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ73493.1 - 0.002 18.7 3.2 1.6 9.5 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ73493.1 - 0.028 15.0 2.4 1.6 9.6 0.1 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ73493.1 - 0.035 13.8 0.0 2.2 8.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat AlaDh_PNT_N PF05222.10 KNZ73494.1 - 1.8e-27 96.0 0.0 2.6e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KNZ73494.1 - 8e-13 48.2 0.0 1.6e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain E2_bind PF08825.5 KNZ73496.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 E2 binding domain zf-Tim10_DDP PF02953.10 KNZ73497.1 - 6.4e-21 73.4 1.1 7.1e-21 73.2 0.8 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Acyltransferase PF01553.16 KNZ73498.1 - 2.1e-20 72.4 0.0 3.3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Abhydrolase_6 PF12697.2 KNZ73500.1 - 1.6e-10 41.2 0.0 1.1e-09 38.5 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ73500.1 - 2.6e-05 23.9 0.0 6.1e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chromo PF00385.19 KNZ73501.1 - 1.9e-07 30.6 4.8 4.1e-07 29.5 3.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Clat_adaptor_s PF01217.15 KNZ73502.1 - 1.3e-17 63.7 2.0 1.4e-17 63.6 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AstE_AspA PF04952.9 KNZ73502.1 - 0.086 11.7 0.0 0.089 11.6 0.0 1.0 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Glucosamine_iso PF01182.15 KNZ73503.1 - 9.7e-66 221.2 0.0 1.1e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ras PF00071.17 KNZ73504.1 - 7.2e-48 162.0 0.5 8.4e-48 161.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ73504.1 - 1.4e-09 38.4 0.0 2.8e-09 37.5 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KNZ73504.1 - 8.5e-09 34.8 0.1 9.6e-09 34.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KNZ73504.1 - 5.4e-06 25.9 0.0 7.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KNZ73504.1 - 0.00089 18.4 0.1 0.0011 18.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 KNZ73504.1 - 0.011 15.2 0.1 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ATG16 PF08614.6 KNZ73505.1 - 1.9e-46 158.3 21.1 2.6e-46 157.8 14.7 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4094 PF13334.1 KNZ73505.1 - 0.022 15.1 7.8 2.1 8.7 2.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) IncA PF04156.9 KNZ73505.1 - 0.046 13.3 23.8 0.027 14.0 2.8 3.0 1 1 1 3 3 3 0 IncA protein TMF_TATA_bd PF12325.3 KNZ73505.1 - 0.09 12.5 25.1 0.21 11.3 1.5 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 KNZ73505.1 - 0.18 12.1 16.8 0.18 12.1 2.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) GAS PF13851.1 KNZ73505.1 - 0.19 10.8 22.0 0.021 14.0 5.8 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 KNZ73505.1 - 0.2 10.8 2.1 0.27 10.3 1.5 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein FlxA PF14282.1 KNZ73505.1 - 0.38 10.7 16.0 0.27 11.2 0.3 3.5 2 1 1 3 3 3 0 FlxA-like protein Snapin_Pallidin PF14712.1 KNZ73505.1 - 0.78 10.0 11.8 2 8.7 3.2 2.6 1 1 1 2 2 2 0 Snapin/Pallidin USP8_interact PF08941.5 KNZ73505.1 - 0.93 8.7 5.9 0.12 11.6 1.2 1.7 2 0 0 2 2 2 0 USP8 interacting FlgN PF05130.7 KNZ73505.1 - 1.8 8.8 19.3 16 5.6 9.6 2.7 1 1 1 2 2 2 0 FlgN protein DUF1664 PF07889.7 KNZ73505.1 - 2.3 8.0 7.1 6.9 6.4 3.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF904 PF06005.7 KNZ73505.1 - 2.7 8.3 22.3 0.73 10.1 3.3 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF904) SlyX PF04102.7 KNZ73505.1 - 2.7 8.4 13.4 0.69 10.3 0.9 3.9 2 1 2 4 4 4 0 SlyX EzrA PF06160.7 KNZ73505.1 - 9 4.3 19.1 1.9 6.5 9.7 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA RRM_1 PF00076.17 KNZ73506.1 - 1.1e-50 169.1 0.0 2.1e-19 68.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ73506.1 - 1.4e-36 124.2 0.0 8.1e-13 48.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ73506.1 - 3.5e-25 87.5 0.0 7.9e-08 32.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KNZ73506.1 - 0.0038 16.9 0.0 5 6.9 0.0 3.1 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Band_7 PF01145.20 KNZ73507.1 - 2.8e-26 92.5 2.0 4.8e-26 91.7 0.9 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF2522 PF10747.4 KNZ73507.1 - 0.047 13.7 0.4 0.081 12.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2522) Asn_synthase PF00733.16 KNZ73509.1 - 1.1e-46 159.3 0.0 2e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KNZ73509.1 - 1.2e-07 31.5 0.0 3.8e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain QueC PF06508.8 KNZ73509.1 - 0.0002 20.7 0.0 0.00035 19.9 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 KNZ73509.1 - 0.054 12.3 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase GATase_6 PF13522.1 KNZ73509.1 - 0.074 13.0 0.0 0.48 10.3 0.0 2.3 2 1 0 2 2 2 0 Glutamine amidotransferase domain 6PGD PF00393.14 KNZ73510.1 - 2.9e-131 436.9 0.0 3.6e-131 436.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KNZ73510.1 - 1.5e-46 158.2 0.0 2.1e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KNZ73510.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Oxysterol_BP PF01237.13 KNZ73511.1 - 2.3e-105 351.9 0.0 3.5e-105 351.3 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 KNZ73511.1 - 1.5e-18 66.6 3.5 3.4e-17 62.2 0.0 3.4 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 KNZ73511.1 - 0.00021 21.4 0.9 0.00089 19.4 0.0 2.6 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 KNZ73511.1 - 0.0026 17.9 0.3 0.015 15.5 0.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain TMF_TATA_bd PF12325.3 KNZ73511.1 - 0.048 13.4 0.1 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Mcp5_PH PF12814.2 KNZ73511.1 - 0.067 13.1 0.2 10 6.0 0.0 3.2 3 0 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology Glyco_hydro_3 PF00933.16 KNZ73512.1 - 8.4e-66 221.9 0.4 1.3e-46 158.9 0.1 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KNZ73512.1 - 2.4e-60 203.8 0.3 8.6e-60 202.0 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KNZ73512.1 - 3.7e-19 68.4 0.0 7.8e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CBM_1 PF00734.13 KNZ73512.1 - 1.4e-05 24.6 2.4 3.2e-05 23.4 1.7 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Aconitase PF00330.15 KNZ73513.1 - 7.5e-137 456.5 0.0 1.4e-135 452.3 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KNZ73513.1 - 5.4e-07 29.7 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain MutS_V PF00488.16 KNZ73514.1 - 4.2e-81 271.7 0.0 7e-81 271.0 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KNZ73514.1 - 1.3e-40 139.3 1.1 2.5e-40 138.4 0.8 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KNZ73514.1 - 3.1e-24 85.1 0.0 8.7e-24 83.7 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KNZ73514.1 - 6.8e-09 35.9 0.0 1.8e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 KNZ73514.1 - 0.061 12.8 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KNZ73514.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 KNZ73515.1 - 7.4e-106 353.2 0.7 8.8e-106 353.0 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KNZ73515.1 - 6.3e-06 26.1 0.0 2.6e-05 24.1 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KNZ73515.1 - 0.00018 21.3 3.5 0.035 13.9 0.0 3.0 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.11 KNZ73515.1 - 0.0061 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KNZ73515.1 - 0.0067 15.6 0.3 0.033 13.3 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KNZ73515.1 - 0.019 15.4 0.1 0.055 13.9 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 KNZ73515.1 - 0.029 13.8 0.1 0.066 12.6 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 KNZ73515.1 - 0.051 13.0 0.0 0.36 10.2 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 KNZ73515.1 - 0.078 13.7 4.2 0.73 10.6 2.9 2.6 1 1 0 1 1 1 0 AAA domain Atg14 PF10186.4 KNZ73515.1 - 0.65 8.8 6.5 0.93 8.3 4.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MIT PF04212.13 KNZ73516.1 - 0.0015 18.3 0.1 0.0031 17.3 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF3391 PF11871.3 KNZ73516.1 - 1.3 9.2 5.9 0.66 10.1 1.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3391) FA_hydroxylase PF04116.8 KNZ73517.1 - 1.7e-13 50.9 18.2 2.2e-13 50.5 12.6 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily FAP PF07174.6 KNZ73518.1 - 0.0011 18.3 3.1 0.0011 18.3 2.2 1.1 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) Helitron_like_N PF14214.1 KNZ73519.1 - 4.4e-23 81.9 0.0 5.6e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ73519.1 - 0.0079 15.7 0.0 0.0094 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) Gemini_AL1 PF00799.15 KNZ73519.1 - 0.019 14.8 0.1 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain PIF1 PF05970.9 KNZ73520.1 - 3.5e-19 68.9 0.0 3.8e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.9 KNZ73523.1 - 1.3e-16 60.4 0.1 1.5e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ73523.1 - 0.00026 20.6 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNZ73523.1 - 0.0013 18.4 0.3 0.0021 17.7 0.2 1.5 1 1 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KNZ73523.1 - 0.0029 17.5 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.10 KNZ73523.1 - 0.0034 17.2 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2791 PF10923.3 KNZ73523.1 - 0.027 13.0 0.0 0.035 12.6 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_25 PF13481.1 KNZ73523.1 - 0.04 13.3 0.1 0.058 12.7 0.1 1.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 KNZ73523.1 - 0.042 13.0 0.0 0.051 12.7 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein Viral_helicase1 PF01443.13 KNZ73523.1 - 0.067 12.7 0.3 0.089 12.2 0.2 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 KNZ73523.1 - 0.068 13.3 0.7 1.4 9.0 0.1 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KNZ73523.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.6 2 0 0 2 2 2 0 RNA helicase CbiA PF01656.18 KNZ73523.1 - 0.1 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.12 KNZ73523.1 - 0.15 11.4 0.1 3.4 6.9 0.0 2.0 1 1 1 2 2 2 0 Thymidylate kinase ATP-synt_ab PF00006.20 KNZ73523.1 - 0.16 11.4 0.2 0.2 11.1 0.1 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PIF1 PF05970.9 KNZ73524.1 - 1e-78 264.8 0.0 1.3e-78 264.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 KNZ73524.1 - 5.1e-07 27.8 0.0 6.7e-07 27.4 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ73524.1 - 0.0028 17.7 0.0 0.0059 16.7 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain F-box-like PF12937.2 KNZ73525.1 - 5.4e-08 32.4 0.5 1.1e-07 31.4 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KNZ73525.1 - 6.2e-06 25.7 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain Death_2 PF14786.1 KNZ73525.1 - 0.046 13.4 0.3 0.098 12.3 0.1 1.6 1 1 1 2 2 2 0 Tube Death domain Lipase_chap PF03280.9 KNZ73525.1 - 0.13 11.8 1.3 0.18 11.3 0.9 1.2 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein SURF4 PF02077.10 KNZ73526.1 - 4.5e-90 301.6 6.1 5.2e-90 301.4 4.3 1.0 1 0 0 1 1 1 1 SURF4 family NUC153 PF08159.7 KNZ73527.1 - 4.7e-13 48.4 0.1 1e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 NUC153 domain Kelch_6 PF13964.1 KNZ73530.1 - 0.09 12.9 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Kelch motif AMP-binding PF00501.23 KNZ73531.1 - 2.8e-69 233.5 0.0 4e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KNZ73531.1 - 3.8e-59 199.6 0.0 9.9e-59 198.2 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 KNZ73531.1 - 4.7e-12 46.0 0.0 1.1e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KNZ73531.1 - 6e-10 39.9 0.0 2.1e-09 38.2 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 KNZ73531.1 - 6.6e-09 35.5 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.15 KNZ73531.1 - 0.022 13.6 0.0 0.043 12.6 0.0 1.5 1 0 0 1 1 1 0 Condensation domain HPIH PF13323.1 KNZ73532.1 - 0.0042 16.7 0.2 0.0079 15.8 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif HMG-CoA_red PF00368.13 KNZ73533.1 - 1.2e-53 182.1 5.4 1.5e-53 181.8 3.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase UBN2_3 PF14244.1 KNZ73534.1 - 4.8e-06 26.1 0.0 0.00077 19.0 0.0 2.1 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type PA PF02225.17 KNZ73534.1 - 0.085 12.5 0.1 0.22 11.2 0.0 1.6 1 1 1 2 2 2 0 PA domain Radial_spoke_3 PF06098.6 KNZ73535.1 - 0.021 13.8 0.3 0.021 13.8 0.2 1.6 1 1 1 2 2 2 0 Radial spoke protein 3 HMG-CoA_red PF00368.13 KNZ73536.1 - 1.4e-72 244.4 5.8 1.7e-72 244.1 4.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase PIF1 PF05970.9 KNZ73538.1 - 9.1e-29 100.5 0.1 1.3e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ73538.1 - 0.0028 17.2 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ73538.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.10 KNZ73538.1 - 0.021 14.6 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KNZ73538.1 - 0.025 14.1 0.1 0.033 13.7 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2791 PF10923.3 KNZ73538.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) PIF1 PF05970.9 KNZ73539.1 - 2.6e-19 69.4 0.2 2.7e-19 69.3 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AMP-binding PF00501.23 KNZ73543.1 - 8.3e-18 63.9 0.0 3.6e-16 58.5 0.0 2.5 2 1 0 2 2 2 2 AMP-binding enzyme adh_short_C2 PF13561.1 KNZ73545.1 - 1.6e-22 80.4 0.0 1.9e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KNZ73545.1 - 1.9e-17 63.6 0.0 3.1e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Ribosomal_L44 PF00935.14 KNZ73546.1 - 2.3e-35 120.4 11.3 3.7e-35 119.7 7.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Acetyltransf_3 PF13302.1 KNZ73547.1 - 1.9e-05 24.8 0.0 4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ73547.1 - 0.00019 21.3 0.0 0.00036 20.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KNZ73547.1 - 0.05 13.4 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NARP1 PF12569.3 KNZ73548.1 - 4e-166 553.7 6.4 6e-165 549.9 0.8 2.8 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 KNZ73548.1 - 2.3e-17 62.3 12.5 0.0011 18.6 2.2 7.8 7 1 0 7 7 7 4 TPR repeat TPR_16 PF13432.1 KNZ73548.1 - 1.9e-16 60.2 10.1 1 10.1 0.1 8.8 7 1 2 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ73548.1 - 4.1e-14 51.2 22.4 0.0074 16.1 0.0 10.4 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ73548.1 - 1.1e-10 41.1 5.2 0.077 13.6 0.0 9.4 7 3 4 11 11 10 1 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ73548.1 - 1.3e-10 41.0 13.2 0.00067 19.5 0.0 6.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ73548.1 - 2.9e-09 36.1 12.7 0.0048 16.4 0.2 8.0 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ73548.1 - 3.6e-08 33.6 17.2 0.97 9.8 0.0 8.5 7 1 2 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ73548.1 - 3.8e-08 33.0 2.1 5.1 7.0 0.0 7.0 6 2 2 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 KNZ73548.1 - 4.8e-08 33.0 4.7 0.035 14.2 2.2 5.9 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KNZ73548.1 - 1.4e-07 31.1 0.0 0.15 12.3 0.0 5.8 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ73548.1 - 3.7e-05 23.2 7.7 1.7 8.6 0.0 5.8 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 KNZ73548.1 - 0.00063 19.9 0.1 1.2 9.7 0.1 4.1 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ73548.1 - 0.0013 18.3 6.1 0.32 10.8 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat MIT PF04212.13 KNZ73548.1 - 0.012 15.4 1.4 0.14 12.0 0.0 3.6 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain Rapsyn_N PF10579.4 KNZ73548.1 - 0.33 10.7 1.7 3.5 7.5 0.0 3.5 4 1 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TPR_6 PF13174.1 KNZ73548.1 - 0.58 10.7 11.6 72 4.1 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat BTAD PF03704.12 KNZ73548.1 - 1.9 8.7 7.9 3.5 7.9 1.7 3.3 3 0 0 3 3 3 0 Bacterial transcriptional activator domain HEAT_2 PF13646.1 KNZ73549.1 - 1.4e-09 38.1 6.9 1.1e-06 28.7 0.1 4.5 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.17 KNZ73549.1 - 0.00034 20.4 3.5 0.57 10.4 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KNZ73549.1 - 0.0063 16.9 3.8 0.83 10.2 0.0 5.1 5 0 0 5 5 5 1 HEAT-like repeat DUF4218 PF13960.1 KNZ73550.1 - 0.0028 17.1 0.1 0.018 14.4 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4218) F-box PF00646.28 KNZ73551.1 - 0.00028 20.4 0.1 0.00081 18.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KNZ73551.1 - 0.0025 17.4 0.5 0.013 15.1 0.1 2.4 3 0 0 3 3 3 1 F-box-like COesterase PF00135.23 KNZ73552.1 - 8.4e-56 189.7 0.0 5.9e-50 170.4 0.0 2.3 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ73552.1 - 0.00072 19.1 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.5 KNZ73552.1 - 0.054 12.3 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Plug_translocon PF10559.4 KNZ73552.1 - 0.12 11.9 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 Plug domain of Sec61p SRP19 PF01922.12 KNZ73553.1 - 5.6e-22 78.1 0.0 1e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein JTB PF05439.7 KNZ73554.1 - 0.054 13.2 0.1 0.054 13.2 0.0 2.2 2 1 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) Glyco_hydro_18 PF00704.23 KNZ73555.1 - 1.7e-60 205.3 2.3 2.3e-60 204.8 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chromo PF00385.19 KNZ73556.1 - 0.00036 20.1 0.9 0.00059 19.4 0.7 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Dak1 PF02733.12 KNZ73557.1 - 4.2e-85 285.1 3.3 7.1e-84 281.1 2.3 2.2 1 1 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KNZ73557.1 - 6.5e-44 149.6 0.1 1.1e-43 148.9 0.1 1.4 1 0 0 1 1 1 1 DAK2 domain F-box-like PF12937.2 KNZ73557.1 - 0.00024 20.7 1.7 0.00059 19.5 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KNZ73557.1 - 0.00025 20.5 0.2 0.00092 18.8 0.2 2.0 1 0 0 1 1 1 1 F-box domain SET PF00856.23 KNZ73559.1 - 7.4e-11 42.6 0.0 1.2e-09 38.7 0.0 2.2 1 1 0 1 1 1 1 SET domain BCNT PF07572.7 KNZ73560.1 - 3.2e-18 65.4 0.0 6.7e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development Bin3 PF06859.7 KNZ73562.1 - 1.7e-33 114.8 0.0 3.4e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.1 KNZ73562.1 - 1.6e-13 50.7 0.0 2.1e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ73562.1 - 4e-13 49.9 0.0 8.4e-13 48.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ73562.1 - 1.7e-09 38.0 0.0 0.0025 18.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ73562.1 - 6.4e-08 32.3 0.0 0.0017 17.9 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ73562.1 - 7.7e-07 29.5 0.0 0.0032 17.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ73562.1 - 1.2e-06 28.5 0.0 3e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KNZ73562.1 - 0.00065 18.9 0.0 0.0019 17.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 KNZ73562.1 - 0.0031 17.8 0.0 0.011 16.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KNZ73562.1 - 0.0057 15.3 0.0 0.016 13.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) POR PF01558.13 KNZ73562.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Ubie_methyltran PF01209.13 KNZ73562.1 - 0.015 14.4 0.0 4.5 6.3 0.0 2.5 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KNZ73562.1 - 0.016 14.3 0.1 1.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.7 KNZ73562.1 - 0.017 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Spermine_synth PF01564.12 KNZ73562.1 - 0.12 11.2 0.0 2.3 7.0 0.0 2.0 2 0 0 2 2 2 0 Spermine/spermidine synthase UCH PF00443.24 KNZ73563.1 - 1.2e-41 142.6 0.0 1.6e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNZ73563.1 - 2.2e-10 40.4 0.6 3.9e-06 26.5 0.1 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Glyco_hydro_1 PF00232.13 KNZ73565.1 - 4.4e-144 480.0 0.2 1.7e-143 478.1 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 KNZ73565.1 - 0.0091 15.4 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core BH4 PF02180.12 KNZ73565.1 - 0.013 15.0 0.5 0.041 13.3 0.4 1.9 1 0 0 1 1 1 0 Bcl-2 homology region 4 gag-asp_proteas PF13975.1 KNZ73567.1 - 0.0096 15.7 0.1 0.021 14.6 0.0 1.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ73567.1 - 0.096 13.1 0.0 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease RVP_2 PF08284.6 KNZ73567.1 - 0.25 11.2 0.9 39 4.1 0.0 2.9 1 1 1 3 3 3 0 Retroviral aspartyl protease PUF PF00806.14 KNZ73568.1 - 1.8e-26 90.1 0.1 1.8e-07 30.2 0.0 6.0 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat Rep_4 PF05797.6 KNZ73568.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) DCP1 PF06058.8 KNZ73569.1 - 2.4e-18 66.3 0.0 1.2e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 Dcp1-like decapping family DUF1768 PF08719.6 KNZ73570.1 - 9.6e-34 116.3 0.0 1.1e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) ORC2 PF04084.9 KNZ73571.1 - 7.8e-80 268.1 0.0 9.7e-80 267.8 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DUF4610 PF15384.1 KNZ73572.1 - 0.38 10.2 5.0 0.27 10.7 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4610) MatE PF01554.13 KNZ73573.1 - 3.2e-53 179.6 26.6 1e-28 99.9 8.2 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KNZ73573.1 - 2.1e-05 24.3 9.5 2.1e-05 24.3 6.6 3.7 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain adh_short PF00106.20 KNZ73574.1 - 1.6e-22 80.1 0.0 2.4e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ73574.1 - 7.5e-12 45.5 0.0 1.7e-11 44.3 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ73574.1 - 4.2e-07 29.8 0.0 1.2e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KNZ73574.1 - 8.1e-07 28.7 0.0 1.3e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KNZ73574.1 - 0.00075 18.4 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KNZ73574.1 - 0.00091 19.2 0.0 0.0013 18.7 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KNZ73574.1 - 0.017 13.8 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Steroid_dh PF02544.11 KNZ73575.1 - 3.6e-34 117.6 2.3 3.6e-34 117.6 1.6 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 KNZ73575.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family APH PF01636.18 KNZ73577.1 - 2.5e-09 37.2 2.1 4e-09 36.5 1.4 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ73577.1 - 0.00098 18.7 0.0 0.002 17.7 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase PRP3 PF08572.5 KNZ73578.1 - 1.6e-64 217.3 2.4 2.8e-64 216.5 1.7 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KNZ73578.1 - 9.9e-32 109.3 0.7 4.3e-31 107.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) BLUF PF04940.7 KNZ73578.1 - 0.11 12.2 0.1 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Sensors of blue-light using FAD TRAP-gamma PF07074.7 KNZ73578.1 - 1.9 7.9 3.8 12 5.3 1.7 2.2 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Ribosomal_L16 PF00252.13 KNZ73579.1 - 5.6e-35 119.9 0.4 7.1e-35 119.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CI-B14_5a PF07347.7 KNZ73580.1 - 0.016 14.9 4.8 0.031 14.0 3.3 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Frigida PF07899.6 KNZ73580.1 - 0.017 13.9 0.8 0.15 10.8 0.0 2.1 2 0 0 2 2 2 0 Frigida-like protein DUF2381 PF09544.5 KNZ73580.1 - 0.045 12.8 6.2 0.083 11.9 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) VirC2 PF07181.6 KNZ73580.1 - 0.15 11.4 4.6 0.25 10.7 3.2 1.3 1 0 0 1 1 1 0 VirC2 protein Acetyltransf_8 PF13523.1 KNZ73581.1 - 1.8e-34 118.8 0.0 2.4e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KNZ73581.1 - 0.0038 17.3 0.1 0.022 14.9 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Transp_cyt_pur PF02133.10 KNZ73582.1 - 4.8e-35 120.9 35.7 1.1e-33 116.4 24.7 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Toxin_4 PF00706.12 KNZ73584.1 - 0.12 12.6 0.5 0.29 11.3 0.1 1.8 2 0 0 2 2 2 0 Anenome neurotoxin ThylakoidFormat PF11264.3 KNZ73585.1 - 0.0047 16.5 0.0 0.0067 16.0 0.0 1.1 1 0 0 1 1 1 1 Thylakoid formation protein SBDS_C PF09377.5 KNZ73588.1 - 0.02 14.6 0.1 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 SBDS protein C-terminal domain DUF3279 PF11682.3 KNZ73588.1 - 0.16 11.5 2.2 0.24 10.9 1.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3279) PIF1 PF05970.9 KNZ73590.1 - 1.5e-29 103.1 0.0 1.7e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 KNZ73590.1 - 0.019 15.0 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain RTBV_P12 PF06361.6 KNZ73593.1 - 0.24 11.6 1.0 0.6 10.3 0.0 2.0 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein AATase PF07247.7 KNZ73594.1 - 0.16 10.4 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase Aldedh PF00171.17 KNZ73595.1 - 7.7e-178 591.5 1.1 8.7e-178 591.3 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KNZ73595.1 - 7.4e-05 21.6 0.0 0.00028 19.7 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Alpha-L-AF_C PF06964.7 KNZ73596.1 - 8e-33 113.6 0.0 2e-32 112.3 0.0 1.7 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminus AAA_17 PF13207.1 KNZ73596.1 - 0.012 16.4 0.0 0.039 14.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain GCN5L1 PF06320.8 KNZ73596.1 - 0.11 12.3 1.6 1.2 9.0 0.3 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) UQ_con PF00179.21 KNZ73597.1 - 9.8e-41 138.4 0.0 1.1e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KNZ73597.1 - 0.00018 21.2 0.0 0.00022 20.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KNZ73597.1 - 0.0071 16.0 0.1 0.014 15.0 0.1 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 KNZ73597.1 - 0.091 12.6 0.1 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain HEAT_2 PF13646.1 KNZ73598.1 - 0.0022 18.2 2.3 0.05 13.8 0.5 2.3 1 1 1 2 2 2 2 HEAT repeats SH3_9 PF14604.1 KNZ73599.1 - 0.00024 20.6 0.1 0.00067 19.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KNZ73599.1 - 0.073 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 SH3 domain zf-RVT PF13966.1 KNZ73601.1 - 0.02 15.1 1.5 0.022 15.0 0.4 1.6 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase DUF677 PF05055.7 KNZ73601.1 - 0.12 11.0 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Glyco_transf_20 PF00982.16 KNZ73603.1 - 1.4e-131 439.2 0.0 1.8e-131 438.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KNZ73603.1 - 3.5e-19 68.6 0.0 8.5e-18 64.1 0.0 2.8 2 1 0 2 2 2 1 Trehalose-phosphatase Metallophos PF00149.23 KNZ73604.1 - 1.6e-38 132.1 0.1 2e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF563 PF04577.9 KNZ73606.1 - 7.8e-20 71.6 0.0 7e-19 68.5 0.0 2.2 1 1 0 2 2 2 1 Protein of unknown function (DUF563) Glyco_hydro_10 PF00331.15 KNZ73608.1 - 1.6e-64 217.9 0.0 1.9e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 ATG13 PF10033.4 KNZ73609.1 - 5.1e-23 81.7 0.0 8.5e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 DUF1796 PF08795.5 KNZ73612.1 - 0.02 14.5 0.1 0.024 14.3 0.1 1.1 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) HsbA PF12296.3 KNZ73614.1 - 0.0003 20.6 0.1 0.00033 20.4 0.0 1.3 1 1 0 1 1 1 1 Hydrophobic surface binding protein A Metallophos PF00149.23 KNZ73615.1 - 0.013 14.8 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase Cutinase PF01083.17 KNZ73617.1 - 4.7e-42 143.7 2.6 5.4e-42 143.5 1.8 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KNZ73617.1 - 1.1e-06 28.2 0.2 1.6e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 KNZ73617.1 - 0.0019 18.1 0.1 0.0032 17.3 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ73617.1 - 0.0045 16.7 0.2 0.0055 16.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ73617.1 - 0.0066 16.0 0.0 0.0073 15.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3089 PF11288.3 KNZ73617.1 - 0.023 13.8 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_8 PF06259.7 KNZ73617.1 - 0.034 13.6 1.7 0.057 12.9 0.2 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase Lipase_3 PF01764.20 KNZ73617.1 - 0.052 13.1 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) BTB PF00651.26 KNZ73618.1 - 0.0013 18.6 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Mob1_phocein PF03637.12 KNZ73619.1 - 6e-17 61.8 0.0 1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family AA_permease_2 PF13520.1 KNZ73622.1 - 7.4e-77 258.6 29.0 9.2e-77 258.3 20.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KNZ73622.1 - 1.6e-21 76.2 25.0 2.2e-21 75.7 17.4 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 KNZ73623.1 - 4e-34 117.9 0.0 4.8e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73623.1 - 1.4e-31 109.4 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KNZ73623.1 - 0.0049 15.9 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ73623.1 - 0.067 12.9 0.2 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family C2 PF00168.25 KNZ73624.1 - 6.2e-20 70.8 0.0 5.3e-10 39.0 0.0 2.6 2 0 0 2 2 2 2 C2 domain Cul7 PF11515.3 KNZ73624.1 - 0.049 13.5 0.2 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 FHA PF00498.21 KNZ73625.1 - 1.2e-07 31.6 0.0 2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain DUF2470 PF10615.4 KNZ73626.1 - 2.6e-10 40.3 0.0 3.7e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 KNZ73626.1 - 1.2e-08 34.7 0.3 2e-08 34.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DNA_binding_1 PF01035.15 KNZ73627.1 - 1.3e-20 72.9 0.0 1.9e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Cu-oxidase PF00394.17 KNZ73628.1 - 1.2e-42 145.4 0.2 2.7e-40 137.8 0.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KNZ73628.1 - 6.8e-33 113.0 8.0 2.8e-31 107.8 0.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KNZ73628.1 - 4e-31 107.2 4.0 1.6e-28 98.8 0.8 3.1 3 0 0 3 3 3 2 Multicopper oxidase gp45-slide_C PF09116.5 KNZ73628.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal FMN_red PF03358.10 KNZ73630.1 - 1.7e-11 43.8 0.0 2e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KNZ73630.1 - 7.6e-07 28.8 0.0 9.8e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 KNZ73630.1 - 1.6e-06 28.1 0.1 6.8e-06 26.1 0.1 2.3 1 1 0 1 1 1 1 Flavodoxin PhoD PF09423.5 KNZ73631.1 - 2.3e-130 435.1 0.1 2.8e-130 434.9 0.1 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos PF00149.23 KNZ73631.1 - 0.052 12.9 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase LRR_8 PF13855.1 KNZ73632.1 - 0.16 11.7 2.8 7.7 6.3 0.2 4.0 3 1 1 4 4 4 0 Leucine rich repeat RRM_1 PF00076.17 KNZ73633.1 - 8e-12 44.6 0.0 1.3e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ73633.1 - 2.7e-09 36.8 0.0 4.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KNZ73633.1 - 1.4e-06 28.6 0.1 2.5e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 KNZ73633.1 - 0.00041 20.1 0.0 0.00063 19.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHP PF02811.14 KNZ73634.1 - 8.2e-10 38.7 0.1 1.2e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 PHP domain WD40 PF00400.27 KNZ73635.1 - 4.3e-46 153.2 29.5 2.4e-09 36.6 0.5 11.0 12 0 0 12 12 12 8 WD domain, G-beta repeat CPSF_A PF03178.10 KNZ73635.1 - 7.6e-05 21.9 0.0 0.077 12.0 0.0 2.5 2 0 0 2 2 2 2 CPSF A subunit region IKI3 PF04762.7 KNZ73635.1 - 0.0041 15.0 0.1 0.18 9.6 0.0 2.3 2 0 0 2 2 2 2 IKI3 family Nbas_N PF15492.1 KNZ73635.1 - 0.0046 16.0 0.5 0.44 9.6 0.0 3.1 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 KNZ73635.1 - 0.014 15.0 0.9 9 6.0 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF4394 PF14339.1 KNZ73635.1 - 0.026 13.7 0.1 0.15 11.2 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4394) PQQ_3 PF13570.1 KNZ73635.1 - 0.37 11.1 8.6 49 4.3 0.0 6.5 8 0 0 8 8 8 0 PQQ-like domain Exo_endo_phos_2 PF14529.1 KNZ73638.1 - 2.2e-09 36.9 0.5 5.7e-09 35.6 0.3 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF1796 PF08795.5 KNZ73638.1 - 0.0047 16.5 0.4 0.015 14.9 0.2 1.9 1 1 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) Glyco_tranf_2_2 PF10111.4 KNZ73638.1 - 0.006 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Exo_endo_phos PF03372.18 KNZ73638.1 - 0.09 12.6 0.4 0.22 11.4 0.2 1.6 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family V_ATPase_I PF01496.14 KNZ73640.1 - 0.0098 13.8 7.6 0.014 13.3 5.3 1.2 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family RVT_thumb PF06817.9 KNZ73640.1 - 0.016 14.7 0.2 0.058 12.9 0.1 2.0 1 0 0 1 1 1 0 Reverse transcriptase thumb domain ROS_MUCR PF05443.6 KNZ73640.1 - 4.3 7.1 9.1 2.1 8.1 0.1 2.6 1 1 2 3 3 3 0 ROS/MUCR transcriptional regulator protein Spc7 PF08317.6 KNZ73640.1 - 4.6 5.7 17.8 4.5 5.8 6.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF572 PF04502.8 KNZ73640.1 - 5.9 6.0 15.4 0.2 10.8 5.1 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF572) Aldedh PF00171.17 KNZ73641.1 - 7.3e-08 31.1 0.0 8.5e-08 30.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_45 PF02015.11 KNZ73641.1 - 0.084 12.9 0.0 0.096 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 Talin_middle PF09141.5 KNZ73641.1 - 0.093 12.4 0.2 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 Talin, middle domain CMAS PF02353.15 KNZ73641.1 - 0.15 11.1 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AMP-binding PF00501.23 KNZ73642.1 - 1.2e-29 102.9 0.2 2.7e-27 95.1 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 KNZ73642.1 - 2.6e-27 95.3 0.0 4e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KNZ73642.1 - 5.4e-07 29.2 0.0 1.4e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ73642.1 - 0.011 15.7 0.0 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 NADH(P)-binding adh_short PF00106.20 KNZ73642.1 - 0.14 12.0 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 short chain dehydrogenase RNase_H PF00075.19 KNZ73644.1 - 6.9e-08 32.9 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 KNZ73644.1 - 0.00025 20.6 0.0 0.00067 19.2 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TauD PF02668.11 KNZ73645.1 - 7.5e-57 192.9 0.4 9.8e-57 192.5 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KNZ73645.1 - 0.00018 21.8 0.0 0.008 16.5 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF971) CsiD PF08943.5 KNZ73645.1 - 0.049 12.5 0.0 0.53 9.1 0.0 1.9 2 0 0 2 2 2 0 CsiD MaoC_dehydratas PF01575.14 KNZ73646.1 - 1.4e-25 89.0 0.0 3.9e-25 87.6 0.0 1.6 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KNZ73646.1 - 1e-07 31.8 0.0 1.2e-06 28.3 0.0 2.2 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase NAD_binding_11 PF14833.1 KNZ73647.1 - 9.3e-29 99.9 0.4 1.8e-28 99.0 0.3 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase HAD_2 PF13419.1 KNZ73647.1 - 1.8e-20 73.9 0.0 4.3e-20 72.6 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KNZ73647.1 - 1.6e-08 35.2 0.2 3.4e-07 30.8 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KNZ73647.1 - 2.2e-06 27.9 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KNZ73647.1 - 0.067 12.7 0.0 2.6 7.5 0.0 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KNZ73647.1 - 0.11 12.3 0.0 6.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 KNZ73647.1 - 0.16 11.3 0.0 9.5 5.5 0.0 2.3 3 0 0 3 3 3 0 HAD superfamily, subfamily IIIB (Acid phosphatase) VWA_2 PF13519.1 KNZ73648.1 - 1e-12 48.4 2.5 1.6e-12 47.8 0.1 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 KNZ73648.1 - 2e-08 33.0 20.8 0.0012 18.2 2.0 3.9 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.9 KNZ73648.1 - 9.3e-07 28.6 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Ssl1-like p450 PF00067.17 KNZ73649.1 - 2.6e-72 243.8 0.0 5.3e-72 242.8 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 Actin PF00022.14 KNZ73650.1 - 1.2e-151 504.6 0.0 1.4e-151 504.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KNZ73650.1 - 0.079 13.3 0.0 0.21 11.9 0.0 1.6 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) EMG1 PF03587.9 KNZ73651.1 - 4e-74 248.2 0.0 4.9e-74 248.0 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase ETF_alpha PF00766.14 KNZ73652.1 - 1.5e-33 114.2 1.8 1.6e-33 114.2 0.3 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 KNZ73652.1 - 1.8e-31 109.0 0.6 3.3e-31 108.2 0.0 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain DUF1620 PF07774.8 KNZ73653.1 - 2.9e-64 216.3 0.0 4.6e-64 215.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KNZ73653.1 - 9.5e-15 54.7 2.0 4.6e-10 39.3 0.2 3.4 2 2 1 3 3 3 3 PQQ-like domain PQQ PF01011.16 KNZ73653.1 - 2.8e-10 39.1 0.1 0.00016 21.0 0.0 3.7 3 0 0 3 3 3 2 PQQ enzyme repeat FolB PF02152.13 KNZ73654.1 - 1.1e-34 118.9 0.0 3.5e-22 78.7 0.0 2.0 2 0 0 2 2 2 2 Dihydroneopterin aldolase Thioredoxin PF00085.15 KNZ73656.1 - 9.7e-51 169.8 0.0 1e-28 99.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.1 KNZ73656.1 - 1.4e-12 47.5 2.6 2.7e-06 27.4 0.0 5.0 3 3 1 4 4 4 2 Thioredoxin-like Thioredoxin_6 PF13848.1 KNZ73656.1 - 6e-11 42.4 0.0 3.4e-05 23.7 0.0 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KNZ73656.1 - 1.5e-10 41.2 1.4 1.5e-06 28.3 0.0 3.9 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 KNZ73656.1 - 1.7e-06 27.7 0.0 0.0054 16.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_4 PF13462.1 KNZ73656.1 - 2.4e-06 27.6 0.2 0.0025 17.8 0.0 3.2 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_7 PF13899.1 KNZ73656.1 - 5.4e-06 26.3 0.9 0.00019 21.3 0.0 2.9 2 0 0 2 2 2 1 Thioredoxin-like HyaE PF07449.6 KNZ73656.1 - 0.00013 21.8 0.0 4.7 7.1 0.0 4.1 5 0 0 5 5 5 1 Hydrogenase-1 expression protein HyaE TraF PF13728.1 KNZ73656.1 - 0.018 14.5 0.0 0.53 9.7 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 KNZ73656.1 - 0.15 11.6 0.3 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin CGI-121 PF08617.5 KNZ73657.1 - 1.1e-23 83.7 0.0 1.3e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 PPR_2 PF13041.1 KNZ73658.1 - 2.8e-44 148.8 9.7 8e-07 28.9 0.5 13.6 10 3 6 16 16 16 12 PPR repeat family PPR PF01535.15 KNZ73658.1 - 2.2e-38 127.5 11.5 1.1e-05 25.1 0.0 15.3 18 0 0 18 18 18 7 PPR repeat PPR_3 PF13812.1 KNZ73658.1 - 6.8e-30 100.8 17.7 0.00014 21.8 0.0 14.0 15 0 0 15 15 15 7 Pentatricopeptide repeat domain PPR_1 PF12854.2 KNZ73658.1 - 3.9e-25 87.0 0.0 3.8e-05 23.0 0.0 9.8 9 0 0 9 9 9 6 PPR repeat TPR_14 PF13428.1 KNZ73658.1 - 1.7e-08 34.3 3.2 2.8 8.8 0.0 9.2 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ73658.1 - 4.9e-06 26.7 0.2 19 5.6 0.0 7.1 9 0 0 9 9 9 0 Tetratricopeptide repeat DUF2235 PF09994.4 KNZ73658.1 - 0.033 13.5 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) SPOB_a PF14689.1 KNZ73658.1 - 0.043 13.3 0.2 0.92 9.1 0.0 3.2 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_7 PF13176.1 KNZ73658.1 - 0.052 13.3 0.0 6.9 6.7 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4614 PF15391.1 KNZ73659.1 - 7.1 6.3 23.4 1.7 8.3 12.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Sec63 PF02889.11 KNZ73660.1 - 2.8e-32 112.2 0.0 4.3e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KNZ73660.1 - 1.1e-16 60.3 0.2 2.1e-16 59.3 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain UPRTase PF14681.1 KNZ73661.1 - 2.5e-74 248.9 0.0 3.1e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KNZ73661.1 - 7.6e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain WD40 PF00400.27 KNZ73663.1 - 7.7e-14 50.9 16.9 2.3e-06 27.2 1.4 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 KNZ73663.1 - 0.00014 21.6 0.1 0.015 15.0 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF2454 PF10521.4 KNZ73664.1 - 9e-37 126.5 0.0 1.6e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) FERM_M PF00373.13 KNZ73665.1 - 2.4 8.3 6.1 3.3 7.8 4.2 1.5 1 1 0 1 1 1 0 FERM central domain EF-hand_1 PF00036.27 KNZ73666.1 - 2.8e-28 95.0 10.6 3.1e-07 29.2 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KNZ73666.1 - 1.6e-26 92.1 2.1 2.3e-14 53.2 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KNZ73666.1 - 1e-21 74.7 7.1 1.7e-05 24.3 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KNZ73666.1 - 5.8e-20 69.6 12.9 4e-06 25.9 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KNZ73666.1 - 2.1e-15 56.0 10.6 0.0001 21.8 0.8 4.5 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 KNZ73666.1 - 9.2e-06 25.3 6.5 0.0031 17.2 0.4 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KNZ73666.1 - 1.7e-05 24.7 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KNZ73666.1 - 0.00071 19.4 0.1 0.31 10.9 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain Anthrax-tox_M PF09156.5 KNZ73666.1 - 0.073 12.1 0.4 0.32 10.0 0.0 1.8 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain TrmE_N PF10396.4 KNZ73667.1 - 3.3e-35 120.4 0.0 6.4e-35 119.5 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 KNZ73667.1 - 3.4e-15 56.0 0.0 6.9e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 KNZ73667.1 - 2.4e-07 31.0 1.3 1.2e-06 28.7 0.0 2.5 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 KNZ73667.1 - 0.0056 15.9 0.0 0.0091 15.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KNZ73667.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AAA_22 PF13401.1 KNZ73667.1 - 0.085 12.9 0.1 1.8 8.7 0.0 2.5 1 1 1 2 2 2 0 AAA domain Miro PF08477.8 KNZ73667.1 - 0.092 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 KNZ73667.1 - 0.12 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 KNZ73667.1 - 0.13 13.0 0.1 0.54 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 KNZ73668.1 - 9.9e-16 56.9 11.1 3.4e-06 26.7 0.2 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat LRR19-TM PF15176.1 KNZ73670.1 - 0.37 10.5 2.4 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain MARVEL PF01284.18 KNZ73670.1 - 6.5 6.5 20.8 9.8 5.9 14.4 1.3 1 0 0 1 1 1 0 Membrane-associating domain tRNA-synt_1g PF09334.6 KNZ73671.1 - 2.5e-90 302.9 0.0 2e-89 299.9 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KNZ73671.1 - 4.7e-19 67.8 0.0 3e-12 45.3 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KNZ73671.1 - 2.9e-09 36.4 0.0 4.1e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 KNZ73671.1 - 0.089 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA SCO1-SenC PF02630.9 KNZ73672.1 - 1.8e-55 187.2 0.0 2.4e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 KNZ73672.1 - 0.00024 21.1 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KNZ73672.1 - 0.0016 18.1 0.0 0.0079 15.8 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family MBOAT PF03062.14 KNZ73673.1 - 4.8e-42 144.2 3.1 4.8e-42 144.2 2.2 1.7 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Abhydrolase_6 PF12697.2 KNZ73674.1 - 4.6e-25 88.8 0.0 6.1e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ73674.1 - 7.7e-09 35.4 0.0 1.9e-08 34.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family GN3L_Grn1 PF08701.6 KNZ73675.1 - 4.2e-23 81.0 18.5 1.2e-22 79.5 12.8 1.8 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 KNZ73675.1 - 8.8e-14 51.4 0.0 7e-12 45.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 KNZ73675.1 - 1.7e-07 30.5 0.1 2.8e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KNZ73675.1 - 2.1e-06 27.0 0.2 3.7e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KNZ73675.1 - 5.2e-05 23.1 5.3 0.00038 20.3 0.6 3.1 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 KNZ73675.1 - 0.00017 21.0 0.6 0.74 9.2 0.0 3.3 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KNZ73675.1 - 0.00042 19.6 0.1 0.0036 16.5 0.0 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B Septin PF00735.13 KNZ73675.1 - 0.002 17.2 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Septin Miro PF08477.8 KNZ73675.1 - 0.006 17.0 0.0 0.024 15.1 0.0 2.1 2 0 0 2 2 1 1 Miro-like protein GBP PF02263.14 KNZ73675.1 - 0.019 14.0 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain MobB PF03205.9 KNZ73675.1 - 0.023 14.3 0.1 0.063 12.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 KNZ73675.1 - 0.032 13.4 0.0 0.085 12.0 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit F-box-like PF12937.2 KNZ73676.1 - 6.9e-05 22.4 3.4 0.00018 21.1 0.2 3.0 3 0 0 3 3 3 1 F-box-like PUF PF00806.14 KNZ73677.1 - 3.1e-15 54.7 0.0 0.0024 17.2 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Ribosomal_L18e PF00828.14 KNZ73678.1 - 5.2e-22 78.5 0.0 5.4e-21 75.3 0.0 2.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 RRM_1 PF00076.17 KNZ73679.1 - 2.6e-17 62.1 0.0 3.5e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ73679.1 - 1.4e-15 56.9 0.0 2e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ73679.1 - 5.9e-15 55.0 0.0 9.1e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 KNZ73679.1 - 0.014 15.1 32.4 0.014 15.1 22.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1777) IBR PF01485.16 KNZ73680.1 - 3.6e-15 55.5 28.8 1.4e-09 37.6 4.9 3.7 3 0 0 3 3 3 2 IBR domain zf-CCCH PF00642.19 KNZ73680.1 - 2.8e-13 49.1 11.0 5.8e-07 29.0 1.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 KNZ73680.1 - 3.3e-06 26.8 5.1 3.3e-06 26.8 3.5 3.8 2 1 1 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KNZ73680.1 - 1.1e-05 25.3 6.7 1.1e-05 25.3 4.7 4.5 2 1 2 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ73680.1 - 2.2e-05 24.0 5.7 2.2e-05 24.0 3.9 4.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KNZ73680.1 - 2.5e-05 23.8 4.0 2.5e-05 23.8 2.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KNZ73680.1 - 0.00028 20.6 6.1 0.00028 20.6 4.2 3.8 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING RRM_1 PF00076.17 KNZ73680.1 - 0.00033 20.2 0.0 0.076 12.6 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_5 PF14634.1 KNZ73680.1 - 0.0023 17.6 6.1 0.0023 17.6 4.2 3.8 2 1 1 3 3 1 1 zinc-RING finger domain RRM_6 PF14259.1 KNZ73680.1 - 0.068 13.1 0.0 2.7 8.0 0.0 2.9 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.1 KNZ73680.1 - 0.62 10.1 19.8 0.019 14.9 1.5 3.2 3 0 0 3 3 2 0 Zinc finger C-x8-C-x5-C-x3-H type MS_channel PF00924.13 KNZ73682.1 - 2.2e-06 27.1 0.1 4.5e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF21 PF01595.15 KNZ73683.1 - 0.28 10.4 3.7 0.53 9.5 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF21 Ribosomal_L12 PF00542.14 KNZ73684.1 - 4.8e-20 71.3 3.4 6.4e-18 64.5 1.9 2.3 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 KNZ73684.1 - 0.019 15.3 10.4 0.019 15.3 7.2 2.4 2 1 1 3 3 3 0 60s Acidic ribosomal protein DUF3782 PF12644.2 KNZ73684.1 - 0.15 11.8 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Not3 PF04065.10 KNZ73685.1 - 3.3e-79 265.4 19.0 3.3e-79 265.4 13.1 1.6 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KNZ73685.1 - 1.6e-43 147.8 7.7 5.6e-43 146.0 5.4 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF641 PF04859.7 KNZ73685.1 - 9.3 6.0 12.2 1.8 8.2 4.1 2.4 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) SH3_1 PF00018.23 KNZ73686.1 - 2.2e-23 81.3 0.0 2.8e-10 39.4 0.0 3.1 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 KNZ73686.1 - 1.1e-20 72.9 0.1 1.2e-09 37.6 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 KNZ73686.1 - 6.3e-17 60.8 0.0 4.5e-10 38.8 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 KNZ73686.1 - 4.3e-08 32.9 0.0 8.4e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 PX domain NDUFA12 PF05071.11 KNZ73687.1 - 1.6e-24 86.3 3.3 2.1e-24 85.9 2.3 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DAO PF01266.19 KNZ73688.1 - 9e-45 153.1 0.0 1.2e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KNZ73688.1 - 0.0003 20.7 0.0 0.00062 19.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KNZ73688.1 - 0.0022 16.9 0.0 0.053 12.4 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KNZ73688.1 - 0.0045 17.0 0.0 0.022 14.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 KNZ73688.1 - 0.047 12.8 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase Semialdhyde_dh PF01118.19 KNZ73688.1 - 0.074 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KNZ73688.1 - 0.075 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 KNZ73688.1 - 0.1 10.7 0.1 0.26 9.4 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_Gly3P_dh_N PF01210.18 KNZ73688.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TPR_11 PF13414.1 KNZ73689.1 - 1.6e-18 66.1 3.3 1.5e-15 56.5 0.7 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KNZ73689.1 - 2.8e-10 39.3 10.2 0.009 15.5 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ73689.1 - 6.6e-06 25.6 11.3 0.061 13.2 0.0 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ73689.1 - 0.0017 18.8 0.1 0.08 13.6 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KNZ73689.1 - 0.0024 17.7 0.5 0.016 15.0 0.0 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 KNZ73689.1 - 0.0083 15.8 0.3 4.5 7.3 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ73689.1 - 0.09 13.4 0.8 18 6.1 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ73689.1 - 0.11 12.8 1.4 3.3 8.1 0.0 3.1 2 2 1 3 3 3 0 Tetratricopeptide repeat Ribosomal_S7e PF01251.13 KNZ73690.1 - 1e-84 282.7 3.3 1.2e-84 282.5 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Ras PF00071.17 KNZ73691.1 - 5.9e-46 155.8 0.0 6.9e-42 142.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KNZ73691.1 - 1.4e-19 70.7 0.0 2.2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ73691.1 - 9.9e-11 41.1 0.0 4.5e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KNZ73691.1 - 1.1e-05 25.3 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KNZ73691.1 - 2.7e-05 23.4 0.0 5.5e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KNZ73691.1 - 0.00013 21.4 0.1 0.0063 16.0 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KNZ73691.1 - 0.00016 21.8 0.0 0.00089 19.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.5 KNZ73691.1 - 0.00025 20.3 0.3 0.00058 19.1 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KNZ73691.1 - 0.0018 17.5 0.0 0.0036 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KNZ73691.1 - 0.0059 16.3 0.0 0.0084 15.8 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase GTP_EFTU PF00009.22 KNZ73691.1 - 0.013 14.9 0.0 0.21 11.0 0.0 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KNZ73691.1 - 0.016 15.1 0.0 0.028 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 KNZ73691.1 - 0.018 14.9 0.0 0.046 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KNZ73691.1 - 0.061 12.9 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KNZ73691.1 - 0.093 13.0 0.0 9.6 6.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KNZ73691.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 KNZ73691.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Septin PF00735.13 KNZ73691.1 - 0.17 10.8 0.1 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Septin AMMECR1 PF01871.12 KNZ73692.1 - 2.3e-40 137.5 0.0 8e-39 132.4 0.0 2.0 1 1 0 1 1 1 1 AMMECR1 Tannase PF07519.6 KNZ73695.1 - 2.8e-88 296.7 0.0 3.9e-88 296.2 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 KNZ73695.1 - 0.00065 19.4 0.0 0.01 15.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ73695.1 - 0.003 17.4 0.0 0.013 15.4 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ73695.1 - 0.0036 16.8 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chs3p PF12271.3 KNZ73696.1 - 1.1e-48 165.7 6.0 1.5e-48 165.3 4.1 1.1 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit BTB PF00651.26 KNZ73697.1 - 8.6e-06 25.7 0.1 1.7e-05 24.7 0.1 1.5 1 1 0 1 1 1 1 BTB/POZ domain Glyco_hydro_11 PF00457.12 KNZ73699.1 - 1.6e-73 245.9 18.9 2.7e-73 245.2 13.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 KNZ73699.1 - 1e-10 41.0 12.2 1e-10 41.0 8.4 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain GPP34 PF05719.6 KNZ73700.1 - 6.4e-60 202.7 0.2 8.2e-60 202.3 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) G-alpha PF00503.15 KNZ73701.1 - 1.6e-104 349.7 0.0 2.2e-93 313.0 0.0 3.3 2 1 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 KNZ73701.1 - 1.1e-05 24.8 1.2 0.00028 20.1 0.1 3.0 3 0 0 3 3 3 1 ADP-ribosylation factor family Ribosomal_L33 PF00471.15 KNZ73702.1 - 4.5e-08 33.2 0.0 5.6e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 DUF4031 PF13223.1 KNZ73704.1 - 0.0042 17.1 0.0 0.0066 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4031) DUF919 PF06034.6 KNZ73704.1 - 0.13 11.9 0.9 5.5 6.6 0.1 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Robl_LC7 PF03259.12 KNZ73705.1 - 1.7e-06 27.4 0.0 4.6e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Roadblock/LC7 domain p450 PF00067.17 KNZ73706.1 - 6.8e-66 222.6 0.0 7.7e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KNZ73707.1 - 8.3e-85 285.0 0.0 9.4e-85 284.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PXB PF12828.2 KNZ73707.1 - 0.16 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 PX-associated HPP PF04982.8 KNZ73708.1 - 2.9e-38 130.4 3.7 2.9e-38 130.4 2.6 1.4 2 0 0 2 2 2 1 HPP family FecCD PF01032.13 KNZ73708.1 - 0.026 13.3 4.0 0.015 14.1 0.7 1.8 1 1 1 2 2 2 0 FecCD transport family Tmemb_14 PF03647.8 KNZ73708.1 - 3.8 7.9 9.1 1.6 9.1 1.8 2.6 1 1 2 3 3 3 0 Transmembrane proteins 14C Ribosomal_L14e PF01929.12 KNZ73710.1 - 1.1e-26 92.9 1.2 1.6e-26 92.4 0.5 1.5 1 1 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 KNZ73710.1 - 0.0001 21.8 0.1 0.00016 21.2 0.1 1.3 1 0 0 1 1 1 1 KOW motif DUF1838 PF08894.6 KNZ73711.1 - 1.1e-51 175.3 0.0 1.4e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1838) His_Phos_2 PF00328.17 KNZ73712.1 - 2.8e-23 82.8 0.0 4.3e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ADH_zinc_N PF00107.21 KNZ73713.1 - 2.2e-10 40.2 0.2 4.4e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KNZ73713.1 - 0.00025 20.6 0.6 0.00062 19.3 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 KNZ73713.1 - 0.0014 17.2 0.4 0.0024 16.4 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 KNZ73713.1 - 0.0032 17.0 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KNZ73713.1 - 0.025 13.4 0.3 0.037 12.8 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain ADH_N PF08240.7 KNZ73713.1 - 0.062 13.0 0.1 2.4 7.9 0.0 2.5 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 KNZ73713.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.14 KNZ73713.1 - 0.14 11.2 0.1 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 KNZ73713.1 - 0.21 10.6 0.6 0.31 10.0 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pkinase_Tyr PF07714.12 KNZ73717.1 - 6.1e-53 179.5 0.0 9e-53 178.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ73717.1 - 7.7e-41 139.9 0.0 1.4e-40 139.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KNZ73717.1 - 0.0017 17.4 0.1 0.0042 16.1 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2226 PF09987.4 KNZ73717.1 - 0.021 13.9 0.1 0.049 12.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) RIO1 PF01163.17 KNZ73717.1 - 0.069 12.4 0.2 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 RIO1 family APG5 PF04106.7 KNZ73719.1 - 0.05 13.0 0.0 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 HK97-gp10_like PF04883.7 KNZ73721.1 - 0.015 16.2 0.7 0.036 14.9 0.5 1.6 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Herpes_UL46 PF03387.9 KNZ73721.1 - 0.3 9.2 2.1 1.1 7.3 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus UL46 protein CNH PF00780.17 KNZ73722.1 - 4.5e-53 180.4 0.0 6.8e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KNZ73722.1 - 4.1e-39 134.3 0.4 6.7e-34 117.3 0.2 2.3 2 0 0 2 2 2 2 RhoGEF domain PH_5 PF15405.1 KNZ73722.1 - 7.5e-14 51.8 0.0 2.8e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KNZ73722.1 - 0.00014 22.0 0.0 0.00038 20.6 0.0 1.8 1 0 0 1 1 1 1 PH domain DEP PF00610.16 KNZ73722.1 - 0.0072 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) zf-C2H2 PF00096.21 KNZ73723.1 - 0.00011 22.2 1.7 0.092 13.1 0.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ73723.1 - 0.0002 21.4 0.7 0.28 11.5 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger DUF678 PF05077.7 KNZ73723.1 - 0.26 11.3 1.7 0.41 10.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Zn-ribbon_8 PF09723.5 KNZ73723.1 - 0.52 10.3 0.0 0.52 10.3 0.0 2.8 3 0 0 3 3 3 0 Zinc ribbon domain adh_short_C2 PF13561.1 KNZ73724.1 - 2.1e-32 112.8 0.1 2.9e-32 112.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KNZ73724.1 - 4.1e-32 111.4 0.2 6.6e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ73724.1 - 2.3e-19 69.7 0.0 1e-18 67.6 0.0 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 KNZ73724.1 - 5.1e-05 22.8 0.1 6.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KNZ73724.1 - 0.019 13.8 0.3 0.032 13.1 0.2 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KNZ73724.1 - 0.045 13.7 0.5 0.1 12.6 0.3 1.7 1 1 0 1 1 1 0 NADH(P)-binding Glyco_transf_5 PF08323.6 KNZ73724.1 - 0.089 12.2 0.0 2.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Starch synthase catalytic domain Ras_bdg_2 PF14847.1 KNZ73724.1 - 0.093 12.6 0.6 0.5 10.3 0.2 2.0 1 1 1 2 2 2 0 Ras-binding domain of Byr2 DUF4170 PF13773.1 KNZ73724.1 - 0.1 12.4 0.3 0.23 11.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) AAA_2 PF07724.9 KNZ73726.1 - 2.9e-47 160.7 0.0 3.9e-45 153.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KNZ73726.1 - 2.9e-20 71.9 2.0 1.2e-19 69.9 0.1 2.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KNZ73726.1 - 6.8e-19 68.3 0.1 5.6e-10 39.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KNZ73726.1 - 4.8e-17 61.9 0.0 7.1e-11 42.0 0.0 3.1 3 1 1 4 4 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KNZ73726.1 - 1.2e-10 41.7 8.3 0.0011 18.9 0.0 5.3 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 KNZ73726.1 - 1.7e-10 41.1 0.2 0.0039 17.3 0.0 4.1 3 1 1 4 4 3 2 AAA domain AAA_17 PF13207.1 KNZ73726.1 - 4.4e-08 33.9 1.8 0.0059 17.4 0.1 3.7 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 KNZ73726.1 - 2.8e-07 30.1 0.0 3.5e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 KNZ73726.1 - 5.2e-07 30.0 0.1 0.058 13.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 KNZ73726.1 - 7.4e-07 29.1 0.0 0.0046 16.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KNZ73726.1 - 8.3e-07 29.5 1.2 0.016 15.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 KNZ73726.1 - 1.2e-06 28.1 0.3 0.03 13.7 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KNZ73726.1 - 1.2e-06 27.8 0.1 0.15 11.1 0.0 3.2 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KNZ73726.1 - 2.7e-05 24.1 0.1 0.27 11.1 0.0 3.8 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 KNZ73726.1 - 4.8e-05 23.6 0.7 0.049 13.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter RuvB_N PF05496.7 KNZ73726.1 - 0.00026 20.1 0.6 0.65 8.9 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 KNZ73726.1 - 0.0003 20.2 0.0 0.76 9.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.17 KNZ73726.1 - 0.00039 20.5 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 KNZ73726.1 - 0.00044 19.9 0.0 0.047 13.4 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_24 PF13479.1 KNZ73726.1 - 0.00045 19.8 0.0 0.23 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KNZ73726.1 - 0.00069 19.3 1.2 4.1 7.0 0.2 4.0 2 2 0 2 2 2 0 Archaeal ATPase T2SE PF00437.15 KNZ73726.1 - 0.00077 18.4 0.0 0.016 14.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 KNZ73726.1 - 0.0011 18.0 0.0 0.088 11.8 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.9 KNZ73726.1 - 0.0013 18.4 0.0 0.56 9.9 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KNZ73726.1 - 0.0016 17.8 0.0 1.2 8.4 0.0 3.3 3 1 0 3 3 2 1 AAA domain DUF258 PF03193.11 KNZ73726.1 - 0.0017 17.6 0.0 1.7 7.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KNZ73726.1 - 0.0045 16.9 0.0 1.4 8.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase NTPase_1 PF03266.10 KNZ73726.1 - 0.0057 16.3 0.2 4.9 6.8 0.1 3.7 3 1 0 3 3 3 0 NTPase NACHT PF05729.7 KNZ73726.1 - 0.0085 15.7 0.0 0.59 9.7 0.0 2.8 2 0 0 2 2 2 1 NACHT domain ATP_bind_1 PF03029.12 KNZ73726.1 - 0.0098 15.4 0.0 0.35 10.3 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 KNZ73726.1 - 0.019 14.8 0.0 7 6.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 KNZ73726.1 - 0.027 14.4 0.1 5.9 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 KNZ73726.1 - 0.028 13.8 0.0 0.39 10.2 0.0 2.6 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.13 KNZ73726.1 - 0.03 13.9 0.1 7.4 6.1 0.0 2.7 3 0 0 3 3 2 0 Bacterial dnaA protein DNA_pol3_delta2 PF13177.1 KNZ73726.1 - 0.034 13.8 0.0 0.21 11.2 0.0 2.3 1 1 0 1 1 1 0 DNA polymerase III, delta subunit SRP54 PF00448.17 KNZ73726.1 - 0.036 13.5 0.0 3.4 7.0 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_3 PF07726.6 KNZ73726.1 - 0.053 13.1 0.1 19 4.8 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KNZ73726.1 - 0.094 13.2 0.0 0.84 10.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein IncA PF04156.9 KNZ73726.1 - 4 6.9 10.4 7.3 6.1 7.2 1.4 1 0 0 1 1 1 0 IncA protein GCV_T PF01571.16 KNZ73727.1 - 6.7e-63 211.8 0.0 8.2e-63 211.5 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KNZ73727.1 - 1.9e-23 82.2 0.2 3.2e-23 81.5 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DeoC PF01791.4 KNZ73728.1 - 2.8e-47 160.9 5.6 3.2e-47 160.8 3.9 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase Cu-oxidase PF00394.17 KNZ73729.1 - 4.7e-46 156.5 0.3 7.7e-44 149.3 0.0 3.2 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KNZ73729.1 - 2.3e-39 133.7 0.0 8.7e-37 125.4 0.0 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KNZ73729.1 - 6e-38 129.4 0.1 8.5e-34 116.0 0.0 3.1 2 1 0 2 2 2 2 Multicopper oxidase TMF_TATA_bd PF12325.3 KNZ73731.1 - 0.032 13.9 1.3 0.052 13.2 0.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding NTR2 PF15458.1 KNZ73731.1 - 0.052 12.7 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 CALCOCO1 PF07888.6 KNZ73731.1 - 0.056 11.7 0.2 0.072 11.3 0.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like MBOAT_2 PF13813.1 KNZ73732.1 - 1.1e-21 76.6 1.1 4.1e-21 74.8 0.4 2.2 1 1 1 2 2 2 1 Membrane bound O-acyl transferase family Helitron_like_N PF14214.1 KNZ73733.1 - 6.2e-36 123.8 1.5 1.5e-35 122.6 0.2 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus SPC12 PF06645.8 KNZ73734.1 - 1.1e-23 82.8 0.3 1.1e-23 82.7 0.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) PIRT PF15099.1 KNZ73734.1 - 0.079 12.1 0.4 0.075 12.2 0.3 1.1 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF1469 PF07332.6 KNZ73734.1 - 1.7 8.3 5.9 2.3 7.9 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) NfeD PF01957.13 KNZ73734.1 - 3.4 7.7 8.6 18 5.4 6.0 1.8 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding QCR10 PF09796.4 KNZ73734.1 - 9 6.0 7.4 1.6 8.4 1.6 1.9 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Pkinase PF00069.20 KNZ73735.1 - 1.7e-13 50.3 0.0 2.6e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KNZ73735.1 - 8.4e-09 35.4 0.4 3e-05 23.8 0.3 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KNZ73735.1 - 6.4e-08 31.9 0.0 9.2e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KNZ73735.1 - 4.5e-06 26.1 1.2 7.8e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KNZ73735.1 - 5.1e-05 22.4 0.1 0.00014 21.0 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Radical_SAM PF04055.16 KNZ73736.1 - 2.1e-16 60.5 0.2 6.6e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KNZ73736.1 - 2.4e-12 46.7 0.1 8.1e-12 45.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KNZ73736.1 - 0.021 14.9 0.0 0.059 13.5 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KNZ73736.1 - 0.033 13.9 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DUF2404 PF10296.4 KNZ73737.1 - 1.7e-05 24.8 0.0 0.00036 20.5 0.0 2.5 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) GDA1_CD39 PF01150.12 KNZ73738.1 - 9e-101 337.4 0.0 1.3e-100 336.9 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 KNZ73738.1 - 0.022 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Tyr_Deacylase PF02580.11 KNZ73739.1 - 2.2e-45 154.1 0.0 2.6e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.16 KNZ73740.1 - 9.9e-16 58.3 0.1 3e-15 56.7 0.1 1.7 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KNZ73741.1 - 7.9e-55 180.8 27.8 1.6e-10 40.4 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KNZ73741.1 - 4.8e-13 48.6 2.6 1.4e-12 47.1 1.8 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ73741.1 - 2.1e-11 43.1 1.8 6.7e-11 41.5 1.2 1.9 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KNZ73741.1 - 5.1e-06 24.9 9.6 0.039 12.0 0.0 5.4 3 1 1 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KNZ73741.1 - 0.00013 20.9 1.1 0.97 8.1 0.1 4.0 3 2 1 4 4 4 2 Nup133 N terminal like Fungal_trans PF04082.13 KNZ73742.1 - 4.3e-17 61.8 1.5 6.5e-17 61.2 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GPI-anchored PF10342.4 KNZ73743.1 - 2.4e-05 24.7 0.0 3.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Terpene_synth_C PF03936.11 KNZ73745.1 - 2e-14 53.4 0.1 2.7e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Adaptin_N PF01602.15 KNZ73745.1 - 0.056 11.7 0.0 0.13 10.5 0.0 1.5 2 0 0 2 2 2 0 Adaptin N terminal region DUF4537 PF15057.1 KNZ73747.1 - 0.00015 21.5 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) PWWP PF00855.12 KNZ73747.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 PWWP domain Nuc_sug_transp PF04142.10 KNZ73748.1 - 1.3e-80 270.0 7.4 2.2e-80 269.2 5.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KNZ73748.1 - 9.9e-09 34.5 7.2 1.4e-08 34.0 5.0 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KNZ73748.1 - 5.5e-08 32.6 19.7 7e-07 29.0 0.4 2.6 3 0 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 KNZ73748.1 - 5.5e-07 29.7 5.3 5.5e-07 29.7 3.7 3.0 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KNZ73748.1 - 0.00031 20.7 5.6 0.00031 20.7 3.9 3.1 2 2 1 3 3 3 1 EamA-like transporter family Mit_ribos_Mrp51 PF11709.3 KNZ73749.1 - 4.5e-15 55.6 0.4 2.5e-14 53.2 0.3 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit DUF2420 PF10336.4 KNZ73749.1 - 0.1 12.1 0.1 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) Mid2 PF04478.7 KNZ73751.1 - 0.0036 16.7 0.1 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor RCR PF12273.3 KNZ73751.1 - 0.0071 16.9 0.6 0.0071 16.9 0.4 2.0 2 1 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red DUF4129 PF13559.1 KNZ73751.1 - 0.02 14.8 0.1 0.048 13.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) EphA2_TM PF14575.1 KNZ73751.1 - 0.02 15.2 0.2 0.051 13.9 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 KNZ73751.1 - 0.064 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Shisa PF13908.1 KNZ73751.1 - 0.066 13.3 0.3 0.18 11.9 0.2 1.9 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 KNZ73751.1 - 0.068 12.8 0.1 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family Adeno_E3_CR2 PF02439.10 KNZ73751.1 - 0.11 12.1 2.9 0.19 11.2 2.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SlyX PF04102.7 KNZ73751.1 - 0.12 12.7 2.3 0.41 11.0 0.2 2.3 2 0 0 2 2 2 0 SlyX MGC-24 PF05283.6 KNZ73751.1 - 2.8 7.6 8.2 0.045 13.5 0.4 1.7 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) zf-C5HC2 PF02928.11 KNZ73752.1 - 0.023 14.7 0.6 0.05 13.6 0.4 1.5 1 0 0 1 1 1 0 C5HC2 zinc finger HALZ PF02183.13 KNZ73752.1 - 0.33 10.6 2.3 0.7 9.6 1.6 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper WD40 PF00400.27 KNZ73752.1 - 3.3 7.7 7.0 0.77 9.7 0.4 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat GMC_oxred_C PF05199.8 KNZ73753.1 - 3.9e-11 43.4 0.1 4.7e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase UPF1_Zn_bind PF09416.5 KNZ73757.1 - 4.3e-70 234.1 2.3 4.3e-70 234.1 1.6 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KNZ73757.1 - 5.7e-59 198.8 0.0 1.1e-58 197.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KNZ73757.1 - 1.3e-55 188.5 2.2 2.2e-55 187.8 1.6 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNZ73757.1 - 1.6e-14 53.4 0.6 4.7e-14 51.9 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KNZ73757.1 - 9.1e-14 51.4 0.1 1.6e-12 47.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KNZ73757.1 - 1.7e-08 34.5 0.0 4.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KNZ73757.1 - 6.1e-07 29.1 0.1 0.04 13.4 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KNZ73757.1 - 9.9e-07 28.0 0.0 1.5e-05 24.1 0.0 2.6 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 KNZ73757.1 - 0.0002 21.0 0.0 0.00043 19.9 0.0 1.6 1 0 0 1 1 1 1 Helicase Ribosomal_S13_N PF08069.7 KNZ73757.1 - 0.00071 19.3 0.1 0.0025 17.5 0.0 2.0 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain PIF1 PF05970.9 KNZ73757.1 - 0.014 14.3 0.2 0.54 9.1 0.0 2.3 1 1 0 2 2 2 0 PIF1-like helicase DEAD PF00270.24 KNZ73757.1 - 0.015 14.8 0.3 0.032 13.7 0.2 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.1 KNZ73757.1 - 0.025 13.9 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_S27e PF01667.12 KNZ73757.1 - 0.052 13.1 0.6 0.17 11.4 0.4 1.8 1 0 0 1 1 1 0 Ribosomal protein S27 SRP54 PF00448.17 KNZ73757.1 - 0.056 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.11 KNZ73757.1 - 0.057 12.6 0.1 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 KNZ73757.1 - 0.06 13.5 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KNZ73757.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain AAA PF00004.24 KNZ73757.1 - 0.14 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KNZ73757.1 - 0.17 11.0 0.0 0.48 9.5 0.0 1.7 2 0 0 2 2 2 0 KaiC ADH_N PF08240.7 KNZ73758.1 - 1.3e-10 41.0 0.0 1.1e-09 37.9 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KNZ73758.1 - 5e-09 35.7 0.0 8.7e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase F-box-like PF12937.2 KNZ73759.1 - 0.00081 19.0 0.1 0.0024 17.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like SNF2_N PF00176.18 KNZ73761.1 - 7.7e-39 133.2 0.0 1e-33 116.4 0.0 2.5 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KNZ73761.1 - 6e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GPI-anchored PF10342.4 KNZ73761.1 - 9.7e-06 25.9 0.0 2.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DEAD PF00270.24 KNZ73761.1 - 9.9e-05 21.8 0.0 0.00032 20.2 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KNZ73761.1 - 0.029 14.2 0.0 13 5.5 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Pam17 PF08566.5 KNZ73762.1 - 2.5e-57 193.3 0.0 3.1e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 SH3_9 PF14604.1 KNZ73763.1 - 4.1e-10 39.0 0.1 1.3e-09 37.4 0.0 2.0 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.23 KNZ73763.1 - 2.3e-05 23.7 0.0 5.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KNZ73763.1 - 0.00062 19.1 0.0 0.0016 17.8 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain AAA_5 PF07728.9 KNZ73764.1 - 2.9e-10 40.0 0.0 5.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KNZ73764.1 - 6.1e-09 36.0 0.0 1.2e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KNZ73764.1 - 0.00022 21.3 0.0 0.00051 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ73764.1 - 0.00039 20.4 0.1 0.0048 16.8 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.24 KNZ73764.1 - 0.00045 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KNZ73764.1 - 0.019 14.8 0.0 0.087 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_PrkA PF08298.6 KNZ73764.1 - 0.026 13.2 0.0 0.052 12.2 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain RNA_helicase PF00910.17 KNZ73764.1 - 0.03 14.4 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 KNZ73764.1 - 0.034 13.2 0.0 0.085 12.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KNZ73764.1 - 0.12 13.1 0.0 0.31 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 KNZ73764.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Sigma54_activat PF00158.21 KNZ73764.1 - 0.24 10.8 0.0 0.46 9.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 KNZ73764.1 - 0.26 11.1 0.0 0.52 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KNZ73764.1 - 0.3 10.4 0.0 0.65 9.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF836 PF05768.9 KNZ73765.1 - 1.3e-11 44.5 0.0 2.9e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) zf-CCHC PF00098.18 KNZ73765.1 - 0.0028 17.5 0.2 0.0047 16.7 0.1 1.4 1 0 0 1 1 1 1 Zinc knuckle YL1 PF05764.8 KNZ73765.1 - 0.014 14.9 4.4 0.025 14.1 3.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 KNZ73765.1 - 0.14 10.0 2.6 0.16 9.8 1.8 1.1 1 0 0 1 1 1 0 Nop14-like family Catalase PF00199.14 KNZ73766.1 - 2.1e-161 536.9 0.2 2.7e-161 536.5 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KNZ73766.1 - 2.8e-14 52.6 0.0 6.1e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 KNZ73766.1 - 2.8e-11 43.0 0.0 5.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Amidohydro_1 PF01979.15 KNZ73767.1 - 9.4e-40 137.2 0.0 1.3e-39 136.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KNZ73767.1 - 1.1e-06 28.0 0.1 0.0013 18.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KNZ73767.1 - 8e-06 25.5 0.0 1.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KNZ73767.1 - 0.00033 20.7 0.0 0.093 12.7 0.1 2.4 2 1 0 2 2 2 2 Amidohydrolase A_deaminase PF00962.17 KNZ73767.1 - 0.00076 18.4 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Phosphodiest PF01663.17 KNZ73768.1 - 5.3e-11 42.4 0.3 8e-11 41.8 0.2 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KNZ73768.1 - 0.00011 21.6 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KNZ73768.1 - 0.00029 20.1 0.1 0.00046 19.4 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Hexapep PF00132.19 KNZ73769.1 - 5.6e-13 47.7 15.9 2.1e-05 23.8 0.2 4.2 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KNZ73769.1 - 0.00067 19.1 13.4 0.026 14.1 4.5 3.2 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase mRNA_cap_enzyme PF01331.14 KNZ73771.1 - 1.8e-49 168.0 0.0 2.4e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KNZ73771.1 - 4.3e-19 68.7 0.1 1e-18 67.5 0.1 1.7 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KNZ73771.1 - 4.4e-08 32.7 0.0 5.1e-07 29.2 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Skp1 PF01466.14 KNZ73772.1 - 5.3e-40 135.3 1.0 7.8e-40 134.7 0.7 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KNZ73772.1 - 5.4e-23 80.8 0.3 1.4e-22 79.5 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 KNZ73772.1 - 0.00079 19.3 0.0 0.033 14.1 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Ribosomal_L27 PF01016.14 KNZ73773.1 - 1.7e-29 101.4 0.4 2.2e-29 101.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein TruB-C_2 PF09157.6 KNZ73773.1 - 0.06 13.2 0.5 1.9 8.4 0.1 2.3 2 0 0 2 2 2 0 Pseudouridine synthase II TruB, C-terminal ECR1_N PF14382.1 KNZ73773.1 - 0.091 12.0 0.0 0.53 9.6 0.0 2.4 2 1 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region DUF3074 PF11274.3 KNZ73774.1 - 3.4e-26 92.0 0.0 6.9e-26 91.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) Gln-synt_C PF00120.19 KNZ73775.1 - 7.7e-56 189.1 0.0 1.6e-54 184.7 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amino_oxidase PF01593.19 KNZ73776.1 - 3.1e-16 59.4 0.1 7.7e-16 58.1 0.1 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KNZ73776.1 - 2.8e-11 43.2 1.2 2.3e-10 40.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KNZ73776.1 - 1.7e-07 30.5 0.0 2.5e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KNZ73776.1 - 0.014 15.4 2.9 0.017 15.2 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNZ73776.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KNZ73776.1 - 0.4 11.1 3.7 1.5 9.2 0.0 3.2 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Glutaredoxin PF00462.19 KNZ73777.1 - 1.7e-17 63.1 0.0 2.8e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin zf-DNL PF05180.7 KNZ73778.1 - 7.3e-28 96.0 0.2 9.4e-28 95.7 0.1 1.1 1 0 0 1 1 1 1 DNL zinc finger Sporozoite_P67 PF05642.6 KNZ73778.1 - 5.4 4.7 8.0 6.3 4.5 5.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Phage-MuB_C PF09077.6 KNZ73779.1 - 0.13 11.9 0.5 0.2 11.3 0.4 1.2 1 0 0 1 1 1 0 Mu B transposition protein, C terminal Tim17 PF02466.14 KNZ73782.1 - 0.14 12.1 0.1 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Aha1_N PF09229.6 KNZ73783.1 - 3.1e-24 85.3 0.0 5.6e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KNZ73783.1 - 3.6e-12 46.4 0.0 1.1e-11 44.8 0.0 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein WD40 PF00400.27 KNZ73783.1 - 1.9e-07 30.7 0.4 0.046 13.6 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_3 PF13570.1 KNZ73783.1 - 0.029 14.6 1.2 2.9 8.3 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain Polyketide_cyc2 PF10604.4 KNZ73783.1 - 0.04 14.0 0.8 0.2 11.8 0.0 2.2 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Terpene_synth_C PF03936.11 KNZ73784.1 - 1.1e-17 64.1 0.2 1.6e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.11 KNZ73785.1 - 5e-17 62.0 0.0 6.9e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF3429 PF11911.3 KNZ73786.1 - 2.2e-37 128.1 13.2 3.2e-37 127.6 9.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF2378 PF09536.5 KNZ73786.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2378) SH3_9 PF14604.1 KNZ73787.1 - 1.8e-07 30.6 0.0 2.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KNZ73787.1 - 6.5e-06 25.4 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KNZ73787.1 - 0.0033 16.8 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF1049 PF06305.6 KNZ73787.1 - 0.14 11.6 0.3 0.24 10.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Mucin PF01456.12 KNZ73787.1 - 1.6 8.5 13.7 3.4 7.4 9.5 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein WD40 PF00400.27 KNZ73788.1 - 1.4e-43 145.2 18.5 5.3e-10 38.7 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KNZ73788.1 - 1.1e-12 47.4 0.8 2.5e-12 46.3 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ73788.1 - 3.3e-08 32.9 0.5 6.6e-08 32.0 0.4 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KNZ73788.1 - 8.6e-07 27.4 2.3 0.021 12.9 0.0 3.9 2 1 2 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KNZ73788.1 - 0.00024 20.6 0.0 0.0037 16.7 0.0 2.5 1 1 0 2 2 2 1 PQQ-like domain DUF787 PF05619.6 KNZ73788.1 - 0.088 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) Kelch_2 PF07646.10 KNZ73788.1 - 0.12 12.2 0.6 3.5 7.5 0.0 3.1 2 1 0 2 2 2 0 Kelch motif Lipase_3 PF01764.20 KNZ73790.1 - 6.6e-06 25.7 0.0 1.7e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KNZ73790.1 - 0.00066 19.4 0.0 0.00095 18.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ73790.1 - 0.007 16.2 0.1 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 KNZ73790.1 - 0.0074 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.15 KNZ73790.1 - 0.093 12.2 0.1 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 KNZ73790.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein TipAS PF07739.8 KNZ73791.1 - 0.022 15.0 0.2 4.4 7.6 0.0 2.3 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain G-gamma PF00631.17 KNZ73792.1 - 1.7e-23 82.0 0.0 1.9e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 GGL domain G-gamma PF00631.17 KNZ73793.1 - 4.2e-14 52.0 0.2 4.7e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 GGL domain COG5 PF10392.4 KNZ73793.1 - 0.13 12.2 0.1 0.14 12.1 0.1 1.0 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Thioredoxin PF00085.15 KNZ73794.1 - 6.3e-23 80.4 0.0 7.9e-23 80.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KNZ73794.1 - 8e-07 29.0 0.0 1.4e-05 25.0 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KNZ73794.1 - 2.2e-06 27.8 0.0 2.7e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KNZ73794.1 - 0.0022 17.9 0.1 0.0031 17.5 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KNZ73794.1 - 0.0026 17.3 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 KNZ73794.1 - 0.0028 17.2 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF2076 PF09849.4 KNZ73795.1 - 1 9.3 8.1 1.4 8.8 5.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.8 KNZ73795.1 - 5.2 7.1 11.7 0.35 10.9 3.9 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Myotub-related PF06602.9 KNZ73796.1 - 1.1e-127 425.7 0.1 1.5e-127 425.2 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 KNZ73796.1 - 0.024 14.9 0.1 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 KNZ73796.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase S-AdoMet_synt_C PF02773.11 KNZ73797.1 - 1.2e-75 251.7 0.3 2.2e-75 250.9 0.2 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KNZ73797.1 - 2.4e-49 166.2 0.0 4.1e-49 165.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KNZ73797.1 - 1.7e-43 146.9 0.2 3.3e-43 145.9 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain GATase_2 PF00310.16 KNZ73798.1 - 2.6e-25 88.9 0.1 1.2e-18 67.0 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KNZ73798.1 - 3.7e-14 52.8 0.0 8.3e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KNZ73798.1 - 1.8e-13 50.3 0.8 3.1e-13 49.5 0.6 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 KNZ73798.1 - 2.3e-12 46.7 0.0 4.4e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KNZ73798.1 - 3.6e-06 25.8 0.0 7.9e-06 24.7 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Glyoxal_oxid_N PF07250.6 KNZ73799.1 - 4.5e-51 173.2 0.0 2e-50 171.1 0.0 2.0 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KNZ73799.1 - 2.2e-16 59.7 0.0 5.9e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 KNZ73799.1 - 0.12 12.2 4.0 2.6 7.8 0.1 4.2 4 0 0 4 4 4 0 Galactose oxidase, central domain AAA_18 PF13238.1 KNZ73800.1 - 2.4e-06 27.8 0.0 3.4e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 KNZ73800.1 - 7e-05 22.5 0.0 9.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 KNZ73800.1 - 0.0023 17.7 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNZ73800.1 - 0.022 14.4 0.0 0.049 13.3 0.0 1.6 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 KNZ73800.1 - 0.13 13.0 0.0 0.19 12.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain KH_1 PF00013.24 KNZ73801.1 - 2.1e-05 24.0 3.3 3.6e-05 23.3 0.7 2.2 2 0 0 2 2 2 1 KH domain Thr_synth_N PF14821.1 KNZ73802.1 - 1.9e-27 95.0 0.0 5.6e-27 93.5 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 KNZ73802.1 - 3.1e-18 66.0 0.0 1e-17 64.3 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme UPF0160 PF03690.8 KNZ73803.1 - 6.9e-12 45.4 0.0 2.6e-11 43.4 0.0 1.7 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0160) THP2 PF09432.5 KNZ73803.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.5 2 0 0 2 2 2 0 Tho complex subunit THP2 p450 PF00067.17 KNZ73805.1 - 2.4e-66 224.1 0.0 5.3e-66 223.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 gag-asp_proteas PF13975.1 KNZ73806.1 - 0.0021 17.8 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease GvpH PF05455.6 KNZ73807.1 - 0.061 12.9 0.8 0.22 11.1 0.0 2.1 2 1 1 3 3 3 0 GvpH Ldh_1_N PF00056.18 KNZ73808.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Aminotran_1_2 PF00155.16 KNZ73813.1 - 7.1e-76 255.5 0.0 9.6e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KNZ73813.1 - 6.5e-05 21.8 0.0 0.00012 20.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KNZ73813.1 - 0.00012 20.5 0.0 0.00033 19.0 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Pertussis_S1 PF02917.9 KNZ73813.1 - 0.017 14.6 0.0 0.044 13.3 0.0 1.6 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 ACT_5 PF13710.1 KNZ73813.1 - 0.19 11.5 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 ACT domain Aminotran_3 PF00202.16 KNZ73814.1 - 1.8e-87 293.3 0.0 2.3e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Sec63 PF02889.11 KNZ73815.1 - 1.8e-78 263.9 0.0 2.7e-78 263.3 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KNZ73815.1 - 1.1e-31 109.6 1.6 3.5e-22 78.6 0.2 4.2 3 1 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ73815.1 - 8.1e-07 28.8 0.0 1.3e-05 24.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ73815.1 - 3.8e-06 26.8 0.3 0.017 14.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KNZ73815.1 - 0.0021 18.2 0.0 4.5 7.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain Aminotran_1_2 PF00155.16 KNZ73816.1 - 5.1e-61 206.6 0.0 5.7e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KNZ73816.1 - 2.6e-08 33.3 0.0 5.6e-08 32.2 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KNZ73816.1 - 3e-06 25.7 0.0 7.5e-06 24.4 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 KNZ73816.1 - 0.00058 19.0 0.0 0.0008 18.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KNZ73816.1 - 0.001 17.9 0.0 0.094 11.4 0.0 2.4 2 0 0 2 2 2 2 Aminotransferase class-V Ank_5 PF13857.1 KNZ73817.1 - 5.2e-35 118.6 4.3 2e-10 40.5 0.1 5.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KNZ73817.1 - 3.3e-33 111.8 1.6 3.2e-07 29.8 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 KNZ73817.1 - 1.9e-32 111.4 0.0 2.5e-21 75.7 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNZ73817.1 - 1.3e-29 101.9 4.4 4.9e-14 52.3 0.4 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ73817.1 - 7.8e-24 81.3 2.6 9e-06 25.4 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat FYVE PF01363.16 KNZ73817.1 - 1.7e-16 59.8 9.3 1.7e-16 59.8 6.5 2.5 2 1 0 2 2 1 1 FYVE zinc finger zf-RING_2 PF13639.1 KNZ73817.1 - 3.3e-11 42.8 4.6 3.3e-11 42.8 3.2 3.6 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KNZ73817.1 - 7.2e-05 22.8 0.8 7.2e-05 22.8 0.5 2.4 3 0 0 3 3 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KNZ73817.1 - 0.0001 22.2 5.2 0.0001 22.2 3.6 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KNZ73817.1 - 0.015 15.2 4.2 0.045 13.7 2.0 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain DUF4611 PF15387.1 KNZ73817.1 - 0.04 14.0 0.2 0.13 12.4 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) zf-C3HC4_3 PF13920.1 KNZ73817.1 - 1.1 8.9 21.1 0.021 14.5 1.8 3.8 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ73817.1 - 2.2 8.0 27.8 0.61 9.8 3.6 4.1 4 0 0 4 4 4 0 zinc-RING finger domain Zn-ribbon_8 PF09723.5 KNZ73817.1 - 8.2 6.4 10.6 1.9 8.5 0.0 3.5 2 1 0 2 2 1 0 Zinc ribbon domain PI31_Prot_N PF11566.3 KNZ73819.1 - 6.2e-27 94.0 0.0 8.2e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KNZ73819.1 - 2.1e-09 37.9 15.5 2.1e-09 37.9 10.7 2.6 3 0 0 3 3 3 1 PI31 proteasome regulator DEAD PF00270.24 KNZ73820.1 - 4.4e-47 159.7 0.0 2.7e-46 157.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ73820.1 - 9e-24 83.1 0.1 3e-23 81.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KNZ73820.1 - 0.00051 18.9 0.0 0.00084 18.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KNZ73820.1 - 0.0045 16.8 0.0 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Nsp1_C PF05064.8 KNZ73821.1 - 4.3e-29 100.5 1.8 1e-28 99.3 1.2 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KNZ73821.1 - 1.3e-07 31.7 118.6 13 6.0 51.6 4.4 1 1 2 3 3 3 2 Nucleoporin FG repeat region FlaC_arch PF05377.6 KNZ73821.1 - 0.12 12.2 2.0 0.58 10.0 0.5 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 KNZ73821.1 - 0.14 11.9 6.6 0.86 9.4 0.0 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3953 PF13129.1 KNZ73822.1 - 0.016 14.8 0.3 0.016 14.8 0.2 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3953) DUF952 PF06108.7 KNZ73823.1 - 1e-23 82.9 0.0 1.3e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) AAA_10 PF12846.2 KNZ73824.1 - 3.2e-12 46.4 0.0 6.4e-12 45.5 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain Zot PF05707.7 KNZ73824.1 - 4.8e-06 26.1 0.0 7.4e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 KNZ73824.1 - 0.00037 20.6 0.1 0.14 12.3 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 KNZ73824.1 - 0.0024 18.0 0.1 0.34 11.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 KNZ73824.1 - 0.0025 17.6 0.1 0.036 13.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 KNZ73824.1 - 0.0059 16.0 0.1 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family DEAD PF00270.24 KNZ73824.1 - 0.044 13.2 0.0 0.63 9.5 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase Adeno_IVa2 PF02456.10 KNZ73824.1 - 0.12 10.9 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein Zeta_toxin PF06414.7 KNZ73824.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Methyltransf_8 PF05148.10 KNZ73825.1 - 9.7e-68 228.0 0.0 2.6e-67 226.6 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KNZ73825.1 - 6.1e-07 29.8 0.0 5.6e-06 26.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ73825.1 - 1.9e-06 27.6 0.0 3.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ73825.1 - 0.00016 21.3 0.0 0.01 15.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ73825.1 - 0.00019 21.8 0.1 0.0012 19.2 0.0 2.4 2 2 1 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ73825.1 - 0.00031 21.2 0.0 0.0011 19.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNZ73825.1 - 0.017 14.2 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KNZ73825.1 - 0.02 15.2 0.1 0.97 9.8 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_29 PF03141.11 KNZ73825.1 - 0.065 11.5 0.0 1.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase UPRTase PF14681.1 KNZ73826.1 - 6.1e-66 221.5 0.0 6.9e-66 221.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KNZ73826.1 - 0.0042 16.7 0.0 0.007 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_1 PF00667.15 KNZ73827.1 - 2.7e-50 170.8 0.0 4.1e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KNZ73827.1 - 1.2e-09 38.7 0.0 3.7e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 KNZ73827.1 - 0.0062 16.4 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase FAD_binding_6 PF00970.19 KNZ73827.1 - 0.078 13.1 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Glyco_hydro_9 PF00759.14 KNZ73828.1 - 1.9e-62 211.6 5.3 3.5e-62 210.7 3.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 BicD PF09730.4 KNZ73829.1 - 0.04 12.2 1.7 0.057 11.7 1.2 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF4094 PF13334.1 KNZ73830.1 - 0.049 14.0 0.2 0.96 9.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) IFP_35_N PF07334.8 KNZ73830.1 - 0.11 12.4 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Rho_GDI PF02115.12 KNZ73831.1 - 3.8e-52 176.6 0.0 4.1e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor UbiA PF01040.13 KNZ73832.1 - 4.2e-23 81.8 19.9 6.6e-23 81.2 13.8 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Rep_fac-A_3 PF08661.6 KNZ73833.1 - 8.8e-18 64.2 0.4 1e-17 64.0 0.3 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Xol-1_GHMP-like PF09109.5 KNZ73833.1 - 0.056 13.5 0.1 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like Myosin_N PF02736.14 KNZ73833.1 - 0.13 11.9 0.1 0.3 10.7 0.1 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Ytp1 PF10355.4 KNZ73834.1 - 1.2e-90 303.3 7.5 2.1e-90 302.5 5.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KNZ73834.1 - 1.7e-14 53.2 0.8 1.7e-14 53.2 0.6 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF3611 PF12263.3 KNZ73834.1 - 0.005 16.2 0.1 0.023 14.1 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) MFS_1 PF07690.11 KNZ73835.1 - 8.9e-35 120.0 14.9 1.5e-34 119.3 9.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily GFO_IDH_MocA PF01408.17 KNZ73838.1 - 4.3e-22 78.8 0.1 8.5e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KNZ73838.1 - 9.3e-06 25.4 0.1 4.9e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain IlvN PF07991.7 KNZ73838.1 - 0.044 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Abhydrolase_6 PF12697.2 KNZ73839.1 - 7.5e-19 68.5 11.0 1.3e-18 67.7 7.6 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ73839.1 - 7.2e-09 35.5 0.4 4.1e-07 29.8 0.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KNZ73839.1 - 3.4e-05 23.5 1.7 0.059 12.9 0.3 2.3 2 0 0 2 2 2 2 Serine hydrolase Abhydrolase_8 PF06259.7 KNZ73839.1 - 0.11 11.9 1.0 0.23 10.9 0.5 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase DUF2048 PF09752.4 KNZ73839.1 - 0.13 11.1 0.1 1.4 7.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) GFO_IDH_MocA PF01408.17 KNZ73841.1 - 4.9e-23 81.9 0.2 9.9e-23 80.9 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KNZ73841.1 - 6e-11 42.1 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 KNZ73841.1 - 0.005 17.1 0.0 0.0087 16.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 KNZ73841.1 - 0.023 15.0 0.0 0.055 13.8 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ubiquitin PF00240.18 KNZ73842.1 - 6.5e-05 22.2 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KNZ73842.1 - 0.053 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain cNMP_binding PF00027.24 KNZ73843.1 - 9.2e-39 131.1 0.0 1.6e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 KNZ73843.1 - 4.2e-12 45.2 0.1 1e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Proteasome PF00227.21 KNZ73844.1 - 3.9e-44 150.2 0.1 4.5e-44 150.0 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit SAC3_GANP PF03399.11 KNZ73845.1 - 1.3e-32 113.0 0.0 3e-32 111.8 0.0 1.6 1 1 1 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KNZ73845.1 - 2.2e-30 105.3 0.0 3.5e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Proteasome PF00227.21 KNZ73846.1 - 8.6e-50 168.6 0.0 1e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KNZ73846.1 - 1.2e-08 34.1 4.3 1.6e-06 27.3 0.2 2.4 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature RecA PF00154.16 KNZ73846.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Nup88 PF10168.4 KNZ73847.1 - 8.3e-20 70.2 0.8 4.6e-08 31.4 0.0 3.3 4 0 0 4 4 4 3 Nuclear pore component Nup54 PF13874.1 KNZ73847.1 - 0.13 11.9 8.2 0.031 13.9 2.3 2.2 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 MFS_1 PF07690.11 KNZ73848.1 - 4.6e-32 111.0 27.0 5.9e-32 110.7 18.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 KNZ73848.1 - 0.0016 18.8 0.1 0.0036 17.6 0.1 1.6 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_hydro_88 PF07470.8 KNZ73849.1 - 5.5e-83 278.7 0.3 6.4e-83 278.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 p450 PF00067.17 KNZ73850.1 - 1.6e-45 155.4 0.0 2.6e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 UBX PF00789.15 KNZ73851.1 - 2.6e-13 49.8 0.3 5e-13 48.9 0.2 1.5 1 0 0 1 1 1 1 UBX domain PITH PF06201.8 KNZ73852.1 - 4.3e-40 136.9 0.0 5.6e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain Mg_trans_NIPA PF05653.9 KNZ73853.1 - 1.2e-55 188.6 7.4 1.5e-55 188.2 5.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KNZ73853.1 - 4.4e-06 26.8 0.2 4.4e-06 26.8 0.1 3.3 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 KNZ73853.1 - 9.8e-06 25.6 0.6 9.8e-06 25.6 0.4 2.8 2 1 0 2 2 2 1 EamA-like transporter family WD40 PF00400.27 KNZ73854.1 - 3e-07 30.0 0.1 1.2e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat Nop10p PF04135.7 KNZ73854.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family TFIID-31kDa PF02291.10 KNZ73855.1 - 9.7e-30 103.0 0.0 1.4e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 KNZ73855.1 - 0.00025 21.1 0.0 0.00061 19.9 0.0 1.6 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 KNZ73855.1 - 0.00076 19.1 0.0 0.0022 17.6 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated Histone PF00125.19 KNZ73855.1 - 0.009 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Nucleoplasmin PF03066.10 KNZ73855.1 - 0.1 12.0 4.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Nucleoplasmin NifU_N PF01592.11 KNZ73856.1 - 6.8e-48 161.7 0.0 9.1e-48 161.3 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain Prp31_C PF09785.4 KNZ73857.1 - 5.5e-38 130.1 4.0 9e-38 129.4 2.8 1.3 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 KNZ73857.1 - 6.4e-38 129.3 0.1 1.1e-37 128.6 0.1 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KNZ73857.1 - 6.9e-16 57.7 0.1 1.6e-15 56.6 0.1 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain Pkinase PF00069.20 KNZ73858.1 - 1.2e-60 204.8 0.0 1.9e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73858.1 - 8.6e-26 90.5 0.0 4.7e-24 84.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ73858.1 - 0.0031 16.5 0.3 0.66 8.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 KNZ73858.1 - 0.13 11.6 1.4 0.36 10.1 1.0 1.7 1 1 0 1 1 1 0 RIO1 family PEX11 PF05648.9 KNZ73860.1 - 3.7e-13 49.2 3.0 4.8e-07 29.2 0.1 3.1 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) DUF3155 PF11352.3 KNZ73860.1 - 0.041 14.1 0.0 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3155) SNARE_assoc PF09335.6 KNZ73861.1 - 1.3e-13 51.2 9.4 1.6e-13 50.9 5.3 2.1 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF2910 PF11139.3 KNZ73861.1 - 0.01 15.0 2.8 0.022 13.8 1.4 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2910) Pkinase PF00069.20 KNZ73862.1 - 2.1e-66 223.7 0.0 3.1e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73862.1 - 1.8e-27 96.0 0.0 1.1e-26 93.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ73862.1 - 1.8e-06 27.1 0.1 0.0013 17.7 0.0 3.0 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 KNZ73862.1 - 0.07 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.11 KNZ73863.1 - 1.9e-37 128.8 40.9 3.6e-37 127.8 27.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily GPI2 PF06432.6 KNZ73863.1 - 0.095 12.0 13.1 0.3 10.4 0.7 2.6 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4231 PF14015.1 KNZ73863.1 - 0.79 9.7 3.4 34 4.4 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) COX14 PF14880.1 KNZ73864.1 - 0.19 11.3 0.9 0.45 10.1 0.7 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Ribosomal_S14 PF00253.16 KNZ73865.1 - 3.5e-16 58.3 1.3 5.4e-16 57.7 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF3425 PF11905.3 KNZ73866.1 - 1.7e-16 60.3 0.2 3.6e-15 56.0 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KNZ73866.1 - 0.00018 21.4 4.0 0.00033 20.5 2.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor Pneumo_att_G PF05539.6 KNZ73866.1 - 0.077 12.3 0.4 0.1 11.9 0.3 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DNA_RNApol_7kD PF03604.8 KNZ73867.1 - 1.8e-17 62.4 8.3 2.5e-17 62.0 5.8 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf-ISL3 PF14690.1 KNZ73867.1 - 0.0035 17.3 1.6 0.012 15.5 0.2 2.1 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.2 KNZ73867.1 - 0.005 16.6 0.8 0.0075 16.0 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 KNZ73867.1 - 0.0053 16.4 0.6 0.0075 15.9 0.4 1.2 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family OrfB_Zn_ribbon PF07282.6 KNZ73867.1 - 0.0053 16.3 1.0 0.033 13.8 0.8 1.9 2 0 0 2 2 2 1 Putative transposase DNA-binding domain Zn_ribbon_recom PF13408.1 KNZ73867.1 - 0.0093 16.2 1.8 0.17 12.1 0.1 2.2 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain DUF2296 PF10058.4 KNZ73867.1 - 0.017 14.8 0.3 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-C3HC PF07967.8 KNZ73867.1 - 0.027 14.2 0.1 0.031 14.0 0.1 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like Zn-ribbon_8 PF09723.5 KNZ73867.1 - 0.049 13.5 2.8 0.11 12.4 1.9 1.6 1 1 0 1 1 1 0 Zinc ribbon domain GFA PF04828.9 KNZ73867.1 - 0.051 13.5 0.8 0.79 9.7 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L37e PF01907.14 KNZ73867.1 - 0.051 13.3 2.5 2.1 8.2 1.7 2.2 1 1 0 1 1 1 0 Ribosomal protein L37e zf-ribbon_3 PF13248.1 KNZ73867.1 - 0.051 12.7 0.4 4.1 6.7 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Cas_CXXC_CXXC PF09706.5 KNZ73867.1 - 0.057 13.5 3.0 1.6 8.9 0.2 2.2 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) zinc_ribbon_2 PF13240.1 KNZ73867.1 - 0.084 12.3 1.0 0.21 11.1 0.7 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-trcl PF13451.1 KNZ73867.1 - 0.15 11.6 6.7 1.6 8.4 0.1 2.4 1 1 1 2 2 2 0 Probable zinc-binding domain TFIIS_C PF01096.13 KNZ73867.1 - 0.18 11.4 1.2 5.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) TF_Zn_Ribbon PF08271.7 KNZ73867.1 - 0.2 11.0 3.0 1.4 8.3 0.1 2.3 1 1 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 KNZ73867.1 - 0.37 10.4 2.8 2.5 7.7 1.9 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 KNZ73867.1 - 0.39 10.3 2.5 9.4 5.8 1.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Zn_Tnp_IS1595 PF12760.2 KNZ73867.1 - 0.7 9.7 3.9 1.7 8.5 2.5 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Mu-like_Com PF10122.4 KNZ73867.1 - 0.88 8.6 4.3 7.1 5.7 0.0 2.2 1 1 1 2 2 2 0 Mu-like prophage protein Com Ribosomal_L44 PF00935.14 KNZ73867.1 - 1.1 9.3 5.4 14 5.8 0.1 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 A2L_zn_ribbon PF08792.5 KNZ73867.1 - 1.9 8.0 4.1 4.1 6.9 0.3 2.1 1 1 2 3 3 3 0 A2L zinc ribbon domain DUF4187 PF13821.1 KNZ73869.1 - 1.1e-19 69.7 0.7 2e-19 68.9 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 KNZ73869.1 - 6e-06 25.9 1.7 1.1e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KNZ73869.1 - 0.12 12.2 0.2 0.41 10.5 0.1 2.0 1 1 0 1 1 1 0 DExH-box splicing factor binding site RRM_1 PF00076.17 KNZ73870.1 - 1.2e-27 95.2 0.0 1.4e-12 47.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ73870.1 - 2e-20 72.5 0.0 2.7e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ73870.1 - 4.4e-11 42.4 0.0 0.00022 21.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KNZ73870.1 - 0.0039 16.8 1.0 0.51 10.1 0.3 3.2 3 0 0 3 3 3 1 Limkain b1 Totivirus_coat PF05518.6 KNZ73870.1 - 0.012 13.4 7.7 0.016 13.0 5.3 1.1 1 0 0 1 1 1 0 Totivirus coat protein OB_RNB PF08206.6 KNZ73870.1 - 0.036 13.5 2.5 7.3 6.1 0.5 3.3 2 1 0 2 2 2 0 Ribonuclease B OB domain DbpA PF03880.10 KNZ73870.1 - 0.046 13.3 0.1 3.8 7.2 0.0 2.7 2 0 0 2 2 2 0 DbpA RNA binding domain Vac7 PF12751.2 KNZ73870.1 - 3 6.5 7.2 1 8.1 3.2 1.5 1 1 0 1 1 1 0 Vacuolar segregation subunit 7 Glyco_hydro_cc PF11790.3 KNZ73871.1 - 5.9e-60 202.6 3.3 8.3e-60 202.1 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Mucin PF01456.12 KNZ73871.1 - 2.1 8.1 19.2 4.2 7.1 13.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.4 KNZ73871.1 - 4 5.6 5.0 5 5.2 3.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_L11 PF00298.14 KNZ73874.1 - 1.6e-28 98.6 0.6 2.8e-28 97.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 KNZ73874.1 - 8.7e-27 92.3 0.2 1.3e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Peptidase_M28 PF04389.12 KNZ73875.1 - 1.7e-21 76.7 0.0 4.4e-21 75.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KNZ73875.1 - 3.9e-07 29.7 0.0 5.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 KNZ73875.1 - 0.0058 15.9 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Nicastrin Asp PF00026.18 KNZ73877.1 - 1.5e-28 99.9 0.0 4.7e-26 91.7 0.0 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNZ73877.1 - 0.00097 19.1 0.5 0.002 18.0 0.3 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KNZ73877.1 - 0.022 15.2 0.1 0.16 12.5 0.0 2.5 3 0 0 3 3 3 0 Aspartyl protease Herpes_gE PF02480.11 KNZ73877.1 - 0.086 11.0 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Esterase_phd PF10503.4 KNZ73878.1 - 4e-11 42.5 0.0 6.1e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 KNZ73878.1 - 1.4e-09 37.4 7.1 4.5e-09 35.8 4.9 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 KNZ73878.1 - 4.5e-08 32.5 0.3 7.1e-08 31.9 0.2 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 KNZ73878.1 - 1.3e-05 24.7 0.2 1.8e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KNZ73878.1 - 0.0012 18.6 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ73878.1 - 0.017 14.9 0.0 0.027 14.3 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.7 KNZ73878.1 - 0.02 13.4 0.0 0.03 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 KNZ73878.1 - 0.059 12.9 0.1 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sporozoite_P67 PF05642.6 KNZ73878.1 - 0.17 9.6 2.5 0.2 9.4 1.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Myco_19_kDa PF05481.7 KNZ73878.1 - 7.7 6.3 9.9 6.3 6.5 1.7 2.4 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen DUF262 PF03235.9 KNZ73879.1 - 2.5e-16 60.3 0.2 1.1e-15 58.2 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function DUF262 DUF605 PF04652.11 KNZ73879.1 - 0.96 8.7 5.9 1.5 8.1 4.1 1.2 1 0 0 1 1 1 0 Vta1 like Tannase PF07519.6 KNZ73880.1 - 1e-101 341.0 0.0 1.4e-101 340.5 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 KNZ73880.1 - 0.00028 20.6 0.0 0.0051 16.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ73880.1 - 0.00078 19.0 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KNZ73880.1 - 0.0025 17.7 0.0 0.007 16.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family F-box-like PF12937.2 KNZ73881.1 - 3.3e-07 29.9 1.5 4.9e-06 26.1 0.2 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KNZ73881.1 - 7.6 6.3 11.3 6.8 6.4 3.7 3.3 2 1 0 2 2 2 0 F-box domain Helitron_like_N PF14214.1 KNZ73882.1 - 4.4e-45 153.6 0.1 8.2e-45 152.7 0.1 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus rve PF00665.21 KNZ73883.1 - 5.3e-07 29.7 0.0 3.7e-06 27.0 0.0 2.1 1 1 1 2 2 2 1 Integrase core domain Med2 PF11214.3 KNZ73884.1 - 0.0072 16.3 0.3 0.017 15.1 0.2 1.5 1 0 0 1 1 1 1 Mediator complex subunit 2 HrpA_pilin PF09589.5 KNZ73885.1 - 0.0066 16.8 0.5 1.4 9.3 0.0 2.5 2 1 0 2 2 2 1 HrpA pilus formation protein BMFP PF04380.8 KNZ73885.1 - 0.04 14.0 4.0 0.06 13.4 1.5 2.3 2 0 0 2 2 2 0 Membrane fusogenic activity Ax_dynein_light PF10211.4 KNZ73885.1 - 0.041 13.7 4.0 0.053 13.3 2.1 1.5 2 0 0 2 2 2 0 Axonemal dynein light chain CTP_transf_2 PF01467.21 KNZ73885.1 - 0.062 13.3 2.1 0.14 12.2 1.5 1.7 1 1 0 1 1 1 0 Cytidylyltransferase DUF3552 PF12072.3 KNZ73885.1 - 0.12 11.5 6.9 0.2 10.8 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) E2R135 PF11570.3 KNZ73885.1 - 0.17 11.9 5.6 0.3 11.1 1.0 2.3 1 1 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 ADIP PF11559.3 KNZ73885.1 - 0.21 11.4 5.4 0.22 11.4 2.6 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 KNZ73885.1 - 0.95 9.4 8.9 2 8.3 5.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Atg14 PF10186.4 KNZ73885.1 - 1.3 7.8 7.8 2.2 7.1 5.2 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KNZ73885.1 - 3.6 7.1 6.8 2.3 7.7 2.3 2.2 2 0 0 2 2 2 0 IncA protein eIF-5_eIF-2B PF01873.12 KNZ73887.1 - 2e-41 140.5 0.1 3.4e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KNZ73887.1 - 2.6e-20 72.1 0.1 8.5e-20 70.5 0.0 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon ATP-synt_F PF01990.12 KNZ73887.1 - 0.032 14.6 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit F_actin_cap_B PF01115.12 KNZ73888.1 - 1.4e-98 328.9 0.0 2.2e-98 328.2 0.0 1.3 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Rabaptin PF03528.10 KNZ73888.1 - 0.053 13.4 0.3 0.11 12.3 0.2 1.5 1 1 0 1 1 1 0 Rabaptin Pro_isomerase PF00160.16 KNZ73889.1 - 7e-26 91.3 0.1 7.9e-26 91.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD G-alpha PF00503.15 KNZ73890.1 - 3.7e-129 430.8 0.1 4.1e-129 430.6 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KNZ73890.1 - 1.1e-13 50.7 0.1 9.2e-11 41.2 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 KNZ73890.1 - 6.3e-05 22.4 0.1 0.011 15.1 0.0 2.3 2 0 0 2 2 2 2 Ras family Gtr1_RagA PF04670.7 KNZ73890.1 - 0.0023 17.1 0.1 0.65 9.0 0.0 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KNZ73890.1 - 0.025 14.0 0.0 0.074 12.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 KNZ73890.1 - 0.041 14.3 0.0 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 KNZ73890.1 - 0.08 12.3 0.0 2.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain HLH PF00010.21 KNZ73891.1 - 9.3e-07 28.4 0.2 2.3e-06 27.2 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF605 PF04652.11 KNZ73891.1 - 0.017 14.5 15.3 0.022 14.2 10.6 1.2 1 0 0 1 1 1 0 Vta1 like THUMP PF02926.12 KNZ73892.1 - 2.9e-11 43.4 0.1 4.1e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 THUMP domain Adipokin_hormo PF06377.6 KNZ73892.1 - 0.16 12.1 0.6 23 5.2 0.0 2.7 2 1 0 2 2 2 0 Adipokinetic hormone NUDIX PF00293.23 KNZ73893.1 - 4e-08 32.9 0.3 6e-08 32.4 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain Zip PF02535.17 KNZ73894.1 - 6.2e-47 160.1 15.2 6.5e-41 140.3 4.8 2.0 2 0 0 2 2 2 2 ZIP Zinc transporter FtsX PF02687.16 KNZ73894.1 - 0.0092 15.7 1.5 0.0092 15.7 1.0 2.0 2 0 0 2 2 2 1 FtsX-like permease family HD PF01966.17 KNZ73895.1 - 6.4e-05 22.9 0.1 0.00019 21.4 0.1 1.8 1 1 0 1 1 1 1 HD domain PEX11 PF05648.9 KNZ73896.1 - 7.4e-12 45.0 0.3 6.8e-11 41.8 0.2 2.3 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) K-box PF01486.12 KNZ73896.1 - 0.26 11.1 0.9 0.42 10.4 0.6 1.2 1 0 0 1 1 1 0 K-box region GMC_oxred_N PF00732.14 KNZ73897.1 - 3.9e-52 177.2 0.0 5.2e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ73897.1 - 1.6e-36 125.7 0.0 3.1e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KNZ73897.1 - 0.00057 18.9 0.1 0.00093 18.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KNZ73897.1 - 0.006 16.5 0.1 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KNZ73897.1 - 0.022 13.6 0.0 0.27 10.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase DNA_pol3_delta2 PF13177.1 KNZ73898.1 - 2.5e-12 46.7 0.1 4.4e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 KNZ73898.1 - 0.00016 21.5 0.1 0.51 10.3 0.0 2.7 3 0 0 3 3 2 2 Replication factor C C-terminal domain AAA PF00004.24 KNZ73898.1 - 0.00028 21.1 0.7 0.00069 19.8 0.5 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNZ73898.1 - 0.0081 16.1 0.5 0.061 13.2 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 KNZ73898.1 - 0.013 14.9 0.8 0.084 12.2 0.6 2.1 1 1 0 1 1 1 0 AAA-like domain DNA_pol3_delta PF06144.8 KNZ73898.1 - 0.013 14.9 0.1 0.021 14.3 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Sigma54_activ_2 PF14532.1 KNZ73898.1 - 0.024 14.6 0.1 0.25 11.3 0.1 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.1 KNZ73898.1 - 0.024 14.5 0.1 0.074 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KNZ73898.1 - 0.028 14.5 1.2 0.2 11.7 0.9 2.2 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KNZ73898.1 - 0.037 13.1 0.1 0.16 11.1 0.0 2.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI SNF2_N PF00176.18 KNZ73898.1 - 0.067 11.9 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF1820 PF08850.6 KNZ73898.1 - 0.079 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) UPF0047 PF01894.12 KNZ73898.1 - 0.087 12.6 0.3 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0047 TSC21 PF15217.1 KNZ73898.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 TSC21 family AAA_23 PF13476.1 KNZ73898.1 - 0.13 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Glyco_hydro_10 PF00331.15 KNZ73899.1 - 1.9e-89 299.8 0.0 2.1e-89 299.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Methyltransf_23 PF13489.1 KNZ73900.1 - 6.4e-05 22.7 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ73900.1 - 0.0058 16.9 0.0 0.031 14.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 KNZ73900.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.1 KNZ73900.1 - 0.014 14.9 0.1 0.087 12.4 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ73900.1 - 0.042 14.4 0.0 0.13 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ73900.1 - 0.046 14.2 0.0 0.34 11.4 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KNZ73900.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain ATP_synt_H PF05493.8 KNZ73901.1 - 3.5e-17 62.2 4.2 4e-17 62.0 2.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit H ARL6IP6 PF15062.1 KNZ73901.1 - 0.02 14.7 0.6 0.027 14.3 0.3 1.4 1 1 0 1 1 1 0 Haemopoietic lineage transmembrane helix DUF1129 PF06570.6 KNZ73901.1 - 0.24 10.6 1.1 0.26 10.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4131 PF13567.1 KNZ73901.1 - 0.43 9.9 5.4 0.45 9.9 3.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) 7kD_coat PF02495.12 KNZ73901.1 - 1.9 8.0 6.4 2 7.9 0.1 2.3 1 1 1 2 2 2 0 7kD viral coat protein Glyco_hydro_10 PF00331.15 KNZ73902.1 - 1.2e-98 330.0 0.0 1.5e-98 329.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 KNZ73902.1 - 7.6e-12 44.6 10.5 7.6e-12 44.6 7.3 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain RAI1 PF08652.6 KNZ73904.1 - 2.4e-21 75.2 0.0 4.8e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Whi5 PF08528.6 KNZ73905.1 - 1.6e-06 27.5 0.0 2.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Sugar_tr PF00083.19 KNZ73906.1 - 3.1e-107 358.9 17.1 3.9e-107 358.6 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ73906.1 - 9.1e-19 67.3 33.8 3.6e-18 65.4 7.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyt-b5 PF00173.23 KNZ73907.1 - 2.3e-18 65.7 0.0 6.5e-18 64.3 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain zf-HC2 PF13490.1 KNZ73909.1 - 0.096 12.6 0.7 0.17 11.8 0.1 1.8 2 0 0 2 2 2 0 Putative zinc-finger TauD PF02668.11 KNZ73910.1 - 3.1e-55 187.6 0.2 3.8e-55 187.3 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glycos_transf_3 PF00591.16 KNZ73912.1 - 4e-75 252.4 0.0 5.1e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KNZ73912.1 - 1.1e-07 31.2 0.0 2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain TRI5 PF06330.6 KNZ73913.1 - 2.6e-20 72.4 1.0 3.2e-20 72.1 0.7 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF2521 PF10730.4 KNZ73913.1 - 0.021 14.6 0.5 0.044 13.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) UBN2_2 PF14227.1 KNZ73914.1 - 8.7e-07 28.5 0.2 1.4e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ73914.1 - 7.5e-05 22.4 0.2 0.00014 21.6 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KNZ73914.1 - 0.00049 19.6 2.6 0.00049 19.6 1.8 2.3 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 KNZ73914.1 - 0.0048 16.2 0.5 0.012 15.0 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) DUF4285 PF14113.1 KNZ73914.1 - 0.045 13.7 0.9 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4285) Glyoxalase_4 PF13669.1 KNZ73916.1 - 0.016 15.1 0.0 0.048 13.6 0.0 1.8 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Arm_2 PF04826.8 KNZ73918.1 - 0.098 11.7 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Armadillo-like HsbA PF12296.3 KNZ73919.1 - 1.1e-16 60.8 0.3 1.4e-16 60.4 0.2 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A CMAS PF02353.15 KNZ73920.1 - 1.7e-43 148.7 0.0 3.9e-43 147.5 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KNZ73920.1 - 2.2e-08 33.9 0.0 5.5e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ73920.1 - 2.8e-07 31.0 0.0 1.3e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ73920.1 - 0.00044 20.6 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ73920.1 - 0.00082 19.8 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ73920.1 - 0.0068 15.8 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KNZ73920.1 - 0.0097 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ73920.1 - 0.048 13.6 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 KNZ73920.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein MetW PF07021.7 KNZ73920.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.14 KNZ73920.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) p450 PF00067.17 KNZ73921.1 - 5.3e-64 216.4 0.0 7e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Na_H_Exchanger PF00999.16 KNZ73922.1 - 8.7e-28 96.9 31.3 1.7e-27 95.9 21.7 1.4 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3278 PF11683.3 KNZ73922.1 - 4.5 7.2 7.0 0.92 9.5 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) MtrG PF04210.8 KNZ73922.1 - 8 6.2 5.7 27 4.5 0.0 3.2 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Thiolase_N PF00108.18 KNZ73923.1 - 4.1e-05 22.6 0.0 0.0012 17.9 0.0 2.0 2 0 0 2 2 2 2 Thiolase, N-terminal domain Fic PF02661.13 KNZ73924.1 - 0.01 16.4 0.0 6.6 7.4 0.1 2.6 1 1 1 2 2 2 0 Fic/DOC family NIP_1 PF08995.5 KNZ73924.1 - 0.094 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Necrosis inducing protein-1 Fic PF02661.13 KNZ73925.1 - 0.012 16.3 0.0 9.8 6.9 0.0 3.1 3 0 0 3 3 3 0 Fic/DOC family JAB PF01398.16 KNZ73926.1 - 1e-15 57.4 1.4 1e-15 57.4 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KNZ73926.1 - 2.8e-08 33.2 0.0 9.4e-08 31.5 0.0 1.9 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Asp PF00026.18 KNZ73927.1 - 4e-31 108.4 0.0 6.5e-30 104.4 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNZ73927.1 - 1.6e-05 24.9 0.4 3.3e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Herpes_gE PF02480.11 KNZ73927.1 - 0.019 13.2 0.0 0.027 12.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Asp_protease_2 PF13650.1 KNZ73927.1 - 0.033 14.6 0.3 0.21 12.1 0.0 2.5 3 0 0 3 3 3 0 Aspartyl protease PB1 PF00564.19 KNZ73928.1 - 3.7e-14 52.1 0.0 7.8e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 PB1 domain G-patch PF01585.18 KNZ73928.1 - 5.4e-07 29.2 0.5 1.4e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 G-patch domain TPR_11 PF13414.1 KNZ73928.1 - 1.8e-06 27.5 2.1 5.3e-06 25.9 0.2 2.8 3 1 1 4 4 4 1 TPR repeat TPR_12 PF13424.1 KNZ73928.1 - 1.1e-05 25.2 0.4 0.0043 16.9 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ73928.1 - 7.8e-05 22.1 0.4 0.003 17.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ73928.1 - 0.00034 20.2 3.3 0.064 13.1 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat G-patch_2 PF12656.2 KNZ73928.1 - 0.001 18.8 0.1 0.001 18.8 0.0 3.9 4 1 0 4 4 4 1 DExH-box splicing factor binding site TPR_1 PF00515.23 KNZ73928.1 - 0.007 15.9 3.7 0.022 14.3 0.0 3.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ73928.1 - 0.046 13.5 0.8 0.78 9.6 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ73928.1 - 4.1 8.0 6.8 18 6.0 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Abhydro_lipase PF04083.11 KNZ73930.1 - 8.6e-24 82.6 0.0 2.2e-23 81.3 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KNZ73930.1 - 3.8e-17 62.6 0.4 1.1e-16 61.0 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KNZ73930.1 - 2.8e-10 40.4 1.0 5.8e-10 39.4 0.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ73930.1 - 1.2e-07 31.5 0.0 9.5e-07 28.6 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 KNZ73930.1 - 0.0053 16.2 0.1 0.059 12.8 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) UPF0029 PF01205.14 KNZ73932.1 - 1.4e-16 60.1 0.1 1.5e-16 59.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Glucosamine_iso PF01182.15 KNZ73933.1 - 8e-21 74.6 0.0 1.7e-20 73.5 0.0 1.5 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAD_binding_8 PF08022.7 KNZ73933.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain Glyco_hydro_15 PF00723.16 KNZ73934.1 - 4.3e-95 318.9 0.1 5e-95 318.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KNZ73934.1 - 1.7e-30 104.4 0.5 3.7e-30 103.3 0.4 1.6 1 0 0 1 1 1 1 Starch binding domain DUF608 PF04685.8 KNZ73934.1 - 0.0006 18.6 0.7 0.00084 18.1 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 zf-C2H2 PF00096.21 KNZ73935.1 - 5.2e-20 70.5 81.9 0.00046 20.3 0.6 11.2 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KNZ73935.1 - 7.1e-12 44.9 71.9 2.2e-07 30.8 0.3 11.9 12 1 1 13 13 13 6 Zinc-finger double domain zf-C2H2_4 PF13894.1 KNZ73935.1 - 3.5e-07 30.0 80.5 0.18 12.2 0.4 10.4 10 1 0 10 10 10 8 C2H2-type zinc finger zf-met PF12874.2 KNZ73935.1 - 0.026 14.7 3.2 0.026 14.7 2.2 7.8 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KNZ73935.1 - 0.07 13.2 30.1 0.75 10.0 0.6 7.2 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding Pro_CA PF00484.14 KNZ73937.1 - 9.3e-25 87.4 0.0 1.2e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase UPF0137 PF03677.8 KNZ73937.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) DUF2407_C PF13373.1 KNZ73938.1 - 2.2e-21 76.2 7.6 1.1e-17 64.3 1.2 3.2 2 1 0 2 2 2 2 DUF2407 C-terminal domain DUF2407 PF10302.4 KNZ73938.1 - 3e-17 62.6 0.0 5.4e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 KNZ73938.1 - 9.5e-05 21.7 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family GIT_SHD PF08518.6 KNZ73939.1 - 1.2e-27 94.8 3.4 1.8e-14 52.7 0.6 2.9 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT TMCO5 PF14992.1 KNZ73939.1 - 1.3 8.1 20.5 0.41 9.7 11.4 2.1 1 1 1 2 2 2 0 TMCO5 family adh_short PF00106.20 KNZ73940.1 - 3e-22 79.3 0.3 3.9e-22 78.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ73940.1 - 1.6e-08 34.6 0.4 2.2e-08 34.1 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ73940.1 - 4.3e-06 26.5 0.2 6.3e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KNZ73940.1 - 0.0053 15.9 0.0 0.067 12.3 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KNZ73940.1 - 0.019 14.9 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding SAM_MT PF04445.8 KNZ73940.1 - 0.067 12.3 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Pyridoxal_deC PF00282.14 KNZ73941.1 - 5.4e-114 380.5 0.0 6.3e-114 380.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KNZ73941.1 - 0.0012 18.0 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 KNZ73941.1 - 0.019 13.5 0.0 0.03 12.8 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.16 KNZ73941.1 - 0.089 11.7 0.0 0.21 10.4 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II PEX-1N PF09262.6 KNZ73942.1 - 1.5e-22 79.4 0.4 4.5e-22 77.8 0.3 1.9 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA PF00004.24 KNZ73942.1 - 2.4e-14 53.6 0.5 3.1e-11 43.5 0.0 3.7 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNZ73942.1 - 1.1e-05 25.5 2.1 4e-05 23.6 0.0 2.6 2 1 2 4 4 3 1 AAA ATPase domain AAA_22 PF13401.1 KNZ73942.1 - 0.0005 20.2 0.5 0.0046 17.1 0.2 2.6 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KNZ73942.1 - 0.00058 19.5 0.0 0.004 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KNZ73942.1 - 0.01 15.2 0.2 0.97 8.8 0.1 2.6 1 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KNZ73942.1 - 0.011 16.5 0.0 0.029 15.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KNZ73942.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KNZ73942.1 - 0.016 13.9 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus NACHT PF05729.7 KNZ73942.1 - 0.016 14.8 1.3 0.62 9.6 0.9 2.4 1 1 0 1 1 1 0 NACHT domain APS_kinase PF01583.15 KNZ73942.1 - 0.023 14.3 0.1 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_19 PF13245.1 KNZ73942.1 - 0.033 13.9 0.1 0.088 12.5 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activ_2 PF14532.1 KNZ73942.1 - 0.034 14.1 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Molydop_binding PF01568.16 KNZ73942.1 - 0.036 13.8 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain AAA_14 PF13173.1 KNZ73942.1 - 0.038 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KNZ73942.1 - 0.043 13.2 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 KNZ73942.1 - 0.054 13.0 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 KNZ73942.1 - 0.085 12.3 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SHS2_FTSA PF02491.15 KNZ73942.1 - 0.091 12.6 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA RNA_helicase PF00910.17 KNZ73942.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_31 PF13614.1 KNZ73942.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KNZ73942.1 - 0.18 10.7 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.6 KNZ73942.1 - 0.18 11.6 0.0 0.46 10.3 0.0 1.6 1 0 0 1 1 1 0 Torsin RNase_P_p30 PF01876.11 KNZ73943.1 - 6.9e-24 83.7 0.0 1.3e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit p30 Polyketide_cyc2 PF10604.4 KNZ73944.1 - 7.4e-05 22.9 1.3 0.00025 21.2 0.9 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 KNZ73944.1 - 0.032 14.2 0.4 0.042 13.8 0.2 1.6 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport GST_N_3 PF13417.1 KNZ73945.1 - 4.2e-25 87.7 0.0 7.6e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KNZ73945.1 - 7.9e-17 61.0 0.0 1.5e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KNZ73945.1 - 8.6e-10 38.6 0.0 1.9e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KNZ73945.1 - 1.9e-06 27.6 0.0 4.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KNZ73945.1 - 5.1e-05 23.1 0.0 0.00012 22.0 0.0 1.6 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KNZ73945.1 - 0.013 15.9 0.0 0.03 14.7 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Gryzun PF07919.7 KNZ73946.1 - 4.1e-48 164.0 0.0 2.6e-46 158.0 0.0 2.2 1 1 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KNZ73946.1 - 1.5e-47 162.1 0.5 1.4e-45 155.7 0.1 2.7 2 1 0 2 2 2 1 Foie gras liver health family 1 TPR_12 PF13424.1 KNZ73946.1 - 8.3e-06 25.6 2.0 0.0066 16.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Gryzun-like PF12742.2 KNZ73946.1 - 1.3e-05 24.9 0.0 3.9e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.3 KNZ73946.1 - 0.0031 17.0 0.0 0.0066 15.9 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_11 PF13414.1 KNZ73946.1 - 0.064 12.9 5.5 0.14 11.8 0.1 3.6 4 0 0 4 4 4 0 TPR repeat TPR_1 PF00515.23 KNZ73946.1 - 0.066 12.8 8.3 0.26 10.9 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KNZ73946.1 - 0.18 11.9 3.6 0.087 12.9 0.2 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KNZ73946.1 - 0.22 11.3 0.8 1.3 8.9 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ73946.1 - 0.67 9.8 3.5 0.63 9.9 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ73946.1 - 6.1 7.0 12.2 0.35 10.9 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ubiquitin PF00240.18 KNZ73947.1 - 4e-08 32.5 0.7 1.3e-07 30.9 0.5 1.7 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 KNZ73947.1 - 2.1e-06 27.9 0.3 6.9e-06 26.2 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 KNZ73947.1 - 0.079 12.6 0.2 0.49 10.1 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SUR7 PF06687.7 KNZ73948.1 - 5.1e-08 32.7 4.3 6.4e-08 32.4 3.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family YfhO PF09586.5 KNZ73948.1 - 0.19 9.6 1.2 0.22 9.5 0.8 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2207 PF09972.4 KNZ73948.1 - 0.92 8.0 6.7 0.94 7.9 4.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Vma12 PF11712.3 KNZ73948.1 - 3.9 7.1 9.3 5.2 6.7 6.4 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase NUDIX PF00293.23 KNZ73950.1 - 3.6e-15 55.8 0.0 6.7e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 KNZ73950.1 - 2.4e-08 34.2 0.2 7.3e-08 32.6 0.1 1.9 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 KNZ73950.1 - 0.0003 20.2 1.3 0.00059 19.2 0.9 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain ABC_membrane PF00664.18 KNZ73951.1 - 1.5e-47 162.2 1.2 2.2e-47 161.7 0.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KNZ73951.1 - 1.2e-30 106.5 0.0 5.4e-30 104.4 0.0 2.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KNZ73951.1 - 1.4e-05 24.4 0.2 0.00048 19.4 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KNZ73951.1 - 0.00094 19.2 0.0 0.031 14.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain DUF87 PF01935.12 KNZ73951.1 - 0.017 14.9 3.9 0.46 10.2 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function DUF87 SbcCD_C PF13558.1 KNZ73951.1 - 0.066 13.1 0.4 0.36 10.7 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Abhydrolase_6 PF12697.2 KNZ73952.1 - 2.2e-23 83.3 0.0 3e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ73952.1 - 7.1e-20 71.2 0.1 9.5e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KNZ73952.1 - 5.7e-18 64.5 0.1 1.4e-17 63.3 0.1 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KNZ73952.1 - 4.4e-05 23.1 0.0 0.029 13.9 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF1749 PF08538.5 KNZ73952.1 - 0.0007 18.5 0.1 0.0025 16.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.16 KNZ73952.1 - 0.0048 16.1 0.1 0.055 12.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KNZ73952.1 - 0.014 14.8 0.5 5.3 6.4 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Tannase PF07519.6 KNZ73952.1 - 0.035 12.8 0.0 0.068 11.8 0.0 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase FSH1 PF03959.8 KNZ73952.1 - 0.11 11.9 0.0 0.3 10.4 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) AXE1 PF05448.7 KNZ73952.1 - 0.15 10.5 0.0 2.2 6.6 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Clathrin_lg_ch PF01086.12 KNZ73953.1 - 3.1e-38 131.9 4.2 4e-38 131.5 2.9 1.1 1 0 0 1 1 1 1 Clathrin light chain DUF4552 PF15089.1 KNZ73953.1 - 0.0076 15.1 2.0 0.2 10.4 0.1 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4552) PGP_phosphatase PF09419.5 KNZ73954.1 - 7.5e-36 123.0 0.0 2.5e-33 114.7 0.0 2.1 1 1 0 1 1 1 1 Mitochondrial PGP phosphatase Glyco_hydro_28 PF00295.12 KNZ73955.1 - 4.3e-57 193.5 10.3 1.1e-56 192.1 7.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 zf-MYND PF01753.13 KNZ73957.1 - 0.029 14.2 1.8 0.05 13.4 1.2 1.4 1 0 0 1 1 1 0 MYND finger DUF4098 PF13345.1 KNZ73959.1 - 0.0084 16.0 5.8 0.5 10.3 0.4 3.4 2 1 1 3 3 3 3 Domain of unknown function (DUF4098) Kri1_C PF12936.2 KNZ73960.1 - 1.7e-24 85.5 0.5 1.7e-24 85.5 0.3 4.8 6 0 0 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.7 KNZ73960.1 - 4.7e-20 71.7 9.0 4.7e-20 71.7 6.3 6.3 5 2 1 6 6 6 1 KRI1-like family MT-A70 PF05063.9 KNZ73962.1 - 0.019 14.5 0.5 0.086 12.3 0.0 2.3 3 0 0 3 3 3 0 MT-A70 RNase_H PF00075.19 KNZ73963.1 - 2.4e-06 27.8 0.1 9.8e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.1 KNZ73963.1 - 0.00013 22.2 1.1 0.00073 19.7 0.7 2.3 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Peptidase_C41 PF05417.6 KNZ73963.1 - 0.026 14.0 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Hepatitis E cysteine protease Pantoate_transf PF02548.10 KNZ73964.1 - 2e-99 331.9 0.0 2.3e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KNZ73964.1 - 0.00045 19.5 0.1 0.0011 18.2 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase PIF1 PF05970.9 KNZ73965.1 - 1.1e-23 83.7 0.0 1.7e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Viral_helicase1 PF01443.13 KNZ73965.1 - 0.032 13.7 0.2 0.049 13.1 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SGT1 PF07093.6 KNZ73965.1 - 0.079 11.3 0.0 0.095 11.0 0.0 1.1 1 0 0 1 1 1 0 SGT1 protein AAA_30 PF13604.1 KNZ73965.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 KNZ73965.1 - 0.15 11.9 0.3 1.3 8.9 0.0 2.4 3 0 0 3 3 3 0 Torsin PIF1 PF05970.9 KNZ73968.1 - 4.4e-11 42.3 0.0 5e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 KNZ73968.1 - 0.0044 16.8 0.0 0.0049 16.7 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 KNZ73968.1 - 0.0044 17.0 0.0 0.0053 16.7 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 KNZ73968.1 - 0.0077 15.4 0.0 0.0092 15.2 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.1 KNZ73968.1 - 0.011 15.1 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KNZ73968.1 - 0.012 16.3 1.8 0.61 10.9 0.1 2.0 1 1 1 2 2 2 0 AAA domain DUF2791 PF10923.3 KNZ73968.1 - 0.034 12.7 0.0 0.042 12.4 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Viral_helicase1 PF01443.13 KNZ73968.1 - 0.034 13.6 0.3 0.055 12.9 0.2 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KNZ73968.1 - 0.039 14.1 0.1 0.083 13.0 0.0 1.5 2 0 0 2 2 2 0 RNA helicase UPF0180 PF03698.8 KNZ73968.1 - 0.041 13.7 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) AAA PF00004.24 KNZ73968.1 - 0.07 13.3 1.0 1.6 8.9 0.1 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KNZ73968.1 - 0.1 12.0 0.0 0.11 11.8 0.0 1.3 1 1 0 1 1 1 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 KNZ73968.1 - 0.14 11.6 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Peptidase_S10 PF00450.17 KNZ73972.1 - 9.8e-80 268.7 0.1 1.4e-79 268.2 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase IGPS PF00218.16 KNZ73973.1 - 5.4e-91 304.1 0.0 1.3e-90 302.8 0.0 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 KNZ73973.1 - 1.2e-45 155.3 0.0 2.2e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.17 KNZ73973.1 - 2.1e-44 151.4 0.0 2.7e-40 138.0 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 KNZ73973.1 - 4.9e-07 29.4 0.0 4.9e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase C26 His_biosynth PF00977.16 KNZ73973.1 - 0.011 15.0 0.0 0.32 10.2 0.0 2.5 2 0 0 2 2 2 0 Histidine biosynthesis protein QRPTase_C PF01729.14 KNZ73973.1 - 0.024 14.1 0.2 1.2 8.5 0.0 3.0 4 0 0 4 4 4 0 Quinolinate phosphoribosyl transferase, C-terminal domain TMP-TENI PF02581.12 KNZ73973.1 - 0.14 11.2 0.2 0.89 8.6 0.0 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Pkinase PF00069.20 KNZ73974.1 - 1.1e-65 221.4 0.0 1.3e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ73974.1 - 7.6e-27 94.0 0.0 1e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ73974.1 - 0.013 15.2 0.2 0.043 13.5 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tetraspannin PF00335.15 KNZ73975.1 - 2.8e-05 23.5 14.5 4.5e-05 22.8 10.0 1.4 1 1 0 1 1 1 1 Tetraspanin family Yip1 PF04893.12 KNZ73975.1 - 0.0088 15.5 14.6 0.013 15.0 10.1 1.1 1 0 0 1 1 1 1 Yip1 domain DUF4293 PF14126.1 KNZ73975.1 - 1.4 8.8 9.7 0.65 9.9 2.8 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4293) MFS_1 PF07690.11 KNZ73975.1 - 1.7 7.2 16.1 4.3 5.9 11.2 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily HAD PF12710.2 KNZ73976.1 - 1.5e-19 70.9 0.0 3.8e-19 69.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KNZ73976.1 - 2.8e-18 65.8 0.0 6.5e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KNZ73976.1 - 1e-13 52.2 3.7 1.6e-12 48.3 2.6 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KNZ73976.1 - 8.8e-13 48.0 0.0 2.2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KNZ73976.1 - 0.0036 16.9 0.1 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase rve PF00665.21 KNZ73979.1 - 0.00096 19.2 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Hist_deacetyl PF00850.14 KNZ73981.1 - 3.7e-55 187.3 0.0 4.7e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Sugar_tr PF00083.19 KNZ73982.1 - 6.3e-43 146.9 23.3 1.5e-42 145.7 16.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ73982.1 - 1.2e-21 76.8 26.4 2.1e-21 76.0 18.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Vps16_C PF04840.7 KNZ73986.1 - 8.3e-81 271.3 0.0 1.1e-80 270.9 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 KNZ73986.1 - 1.6e-75 254.2 0.0 2.1e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region DUF4331 PF14224.1 KNZ73986.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4331) tRNA-synt_1d PF00750.14 KNZ73989.1 - 1.6e-88 296.8 4.2 2.3e-88 296.4 2.9 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KNZ73989.1 - 2.1e-12 47.0 0.0 5.1e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain RRM_1 PF00076.17 KNZ73990.1 - 3.8e-41 138.5 0.1 3.6e-20 71.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ73990.1 - 6.4e-32 109.3 0.0 1.1e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ73990.1 - 4.9e-15 55.1 0.0 4.4e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GDI PF00996.13 KNZ73991.1 - 5.7e-58 196.2 0.0 7.6e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 KNZ73991.1 - 2.9e-05 23.9 0.0 6.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KNZ73991.1 - 0.0046 15.8 0.2 0.0071 15.2 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KNZ73991.1 - 0.011 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KNZ73991.1 - 0.028 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KNZ73991.1 - 0.046 12.5 0.1 0.076 11.8 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KNZ73991.1 - 0.06 12.9 0.4 0.57 9.7 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 KNZ73991.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KNZ73991.1 - 0.13 11.3 0.6 0.23 10.5 0.1 1.6 2 0 0 2 2 2 0 Thi4 family DUF2638 PF10937.3 KNZ73993.1 - 3e-11 44.3 2.5 4e-05 24.6 0.3 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2638) CTK3 PF12243.3 KNZ73993.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Proteasome PF00227.21 KNZ73994.1 - 5.4e-46 156.2 0.1 2.6e-45 154.0 0.1 1.8 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KNZ73994.1 - 3.2e-15 55.1 0.4 6.2e-15 54.2 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flagellin_N PF00669.15 KNZ73994.1 - 0.063 13.0 0.5 0.12 12.1 0.3 1.4 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region RNA_pol_Rpb1_5 PF04998.12 KNZ73995.1 - 7.6e-94 314.0 0.1 1.2e-93 313.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KNZ73995.1 - 9.8e-87 291.3 0.0 1.7e-86 290.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KNZ73995.1 - 1.1e-67 227.1 0.0 5.3e-67 224.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KNZ73995.1 - 1.2e-33 116.1 0.2 2.7e-32 111.7 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KNZ73995.1 - 9.7e-33 112.1 0.2 3.5e-32 110.3 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Zn_Tnp_IS1 PF03811.8 KNZ73995.1 - 0.017 14.6 0.1 0.039 13.4 0.0 1.6 1 0 0 1 1 1 0 InsA N-terminal domain DUF1317 PF07026.6 KNZ73995.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) TPR_11 PF13414.1 KNZ73996.1 - 1e-09 37.8 16.3 2e-06 27.3 0.0 5.8 5 1 0 5 5 5 3 TPR repeat TPR_1 PF00515.23 KNZ73996.1 - 2.6e-09 36.2 2.2 2.1e-05 23.9 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ73996.1 - 5.9e-07 29.1 15.9 0.61 10.4 0.0 7.7 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ73996.1 - 9.9e-07 28.2 21.3 0.00014 21.4 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ73996.1 - 4.4e-06 26.8 24.3 0.0043 17.5 0.0 7.2 5 2 2 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KNZ73996.1 - 0.00032 20.7 5.3 0.88 9.7 0.0 4.8 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KNZ73996.1 - 0.00044 19.8 0.2 0.2 11.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ73996.1 - 0.003 18.1 0.1 0.003 18.1 0.0 5.9 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ73996.1 - 0.057 13.3 0.1 0.057 13.3 0.1 5.6 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ73996.1 - 3.9 7.8 23.6 2.6 8.4 0.2 6.4 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ73996.1 - 4.9 7.8 9.9 79 4.0 0.2 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF3504 PF12012.3 KNZ73997.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Patatin PF01734.17 KNZ73998.1 - 8.7e-19 68.2 0.1 2e-18 67.1 0.0 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase Med13_C PF06333.7 KNZ74001.1 - 1e-22 80.2 0.1 1e-22 80.2 0.1 3.1 3 1 1 4 4 4 1 Mediator complex subunit 13 C-terminal DUF2433 PF10360.4 KNZ74002.1 - 1.7e-29 102.8 0.0 6.6e-29 100.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_6 PF14259.1 KNZ74002.1 - 0.01 15.7 0.0 0.03 14.2 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) U79_P34 PF03064.11 KNZ74002.1 - 0.029 13.8 5.5 0.055 12.9 3.8 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RRM_1 PF00076.17 KNZ74002.1 - 0.034 13.7 0.0 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1510 PF07423.6 KNZ74002.1 - 0.078 12.3 8.6 0.12 11.6 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FLO_LFY PF01698.11 KNZ74002.1 - 0.16 10.7 4.0 0.26 10.0 2.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein CT47 PF15623.1 KNZ74002.1 - 0.28 10.8 11.1 0.53 9.9 7.7 1.4 1 0 0 1 1 1 0 Cancer/testis gene family 47 Ycf1 PF05758.7 KNZ74002.1 - 0.29 8.7 0.5 0.36 8.4 0.3 1.1 1 0 0 1 1 1 0 Ycf1 Hex_IIIa PF02455.11 KNZ74002.1 - 0.38 9.4 2.7 0.55 8.8 1.9 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Vfa1 PF08432.5 KNZ74002.1 - 0.46 10.4 11.5 0.77 9.7 8.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NARP1 PF12569.3 KNZ74002.1 - 1.2 7.7 15.2 1.9 7.1 10.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNA_polI_A34 PF08208.6 KNZ74002.1 - 1.5 8.4 19.4 2.6 7.6 13.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.7 KNZ74002.1 - 2.7 7.8 12.6 6 6.6 8.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 F_bP_aldolase PF01116.15 KNZ74003.1 - 5.2e-97 324.3 0.0 6.6e-97 324.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Torsin PF06309.6 KNZ74003.1 - 0.038 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Torsin tRNA-synt_1 PF00133.17 KNZ74006.1 - 8.7e-210 697.7 0.0 3e-209 695.9 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) SIN1 PF05422.7 KNZ74006.1 - 3.6e-41 141.2 0.0 1.2e-25 90.0 0.0 2.3 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) Anticodon_1 PF08264.8 KNZ74006.1 - 4.6e-35 120.6 0.4 1.2e-34 119.2 0.3 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KNZ74006.1 - 4.3e-16 58.5 0.0 1.1e-08 34.1 0.0 4.2 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KNZ74006.1 - 1.3e-10 40.8 0.1 3.2e-07 29.8 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 KNZ74006.1 - 0.0073 15.1 0.0 0.02 13.6 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (R) TUG-UBL1 PF11470.3 KNZ74006.1 - 0.091 12.6 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 GLUT4 regulating protein TUG tRNA-synt_1e PF01406.14 KNZ74006.1 - 0.18 10.9 0.0 0.53 9.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Ribosomal_L5_C PF00673.16 KNZ74007.1 - 4.3e-14 52.0 0.0 1e-13 50.8 0.0 1.6 1 1 0 1 1 1 1 ribosomal L5P family C-terminus CRAL_TRIO PF00650.15 KNZ74008.1 - 4.5e-33 113.9 0.0 6.1e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KNZ74008.1 - 8.5e-15 54.6 1.3 2.3e-14 53.2 0.9 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KNZ74008.1 - 0.036 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KNZ74009.1 - 3.7e-34 117.5 0.0 5.6e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KNZ74009.1 - 4.2e-12 45.9 1.6 4.2e-12 45.9 1.1 2.2 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KNZ74009.1 - 0.002 18.0 0.0 0.073 12.9 0.0 2.1 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Abhydrolase_6 PF12697.2 KNZ74010.1 - 3.9e-27 95.6 0.0 4.6e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ74010.1 - 2.3e-20 73.1 0.0 1.4e-19 70.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ74010.1 - 6e-10 39.0 0.0 1.2e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ74010.1 - 0.00026 20.2 0.1 0.34 10.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 KNZ74010.1 - 0.0023 17.7 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DUF2048 PF09752.4 KNZ74010.1 - 0.0029 16.5 0.1 0.25 10.1 0.1 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2048) Thioesterase PF00975.15 KNZ74010.1 - 0.0075 16.5 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 KNZ74010.1 - 0.011 15.3 0.0 0.12 11.9 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold HSF_DNA-bind PF00447.12 KNZ74010.1 - 0.023 14.8 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 HSF-type DNA-binding POP1 PF06978.6 KNZ74011.1 - 0.0084 15.7 0.9 0.012 15.3 0.6 1.3 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 ATP-synt_S1 PF05827.7 KNZ74012.1 - 6.2e-12 45.4 6.2 4.2e-10 39.4 4.3 2.0 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Tiny_TM_bacill PF09680.5 KNZ74012.1 - 0.72 9.3 5.9 1.2 8.6 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (Tiny_TM_bacill) Plant_NMP1 PF06694.6 KNZ74013.1 - 0.087 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) GMC_oxred_C PF05199.8 KNZ74015.1 - 1.4e-38 132.3 0.0 1.8e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase AMP-binding PF00501.23 KNZ74016.1 - 8.6e-17 60.6 0.0 6.9e-15 54.3 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme DnaJ PF00226.26 KNZ74019.1 - 6.9e-17 60.9 0.2 6.9e-17 60.9 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain Borrelia_P83 PF05262.6 KNZ74019.1 - 0.0033 15.7 18.3 0.0044 15.3 12.7 1.3 1 0 0 1 1 1 1 Borrelia P83/100 protein RNase_H PF00075.19 KNZ74022.1 - 1.1e-07 32.2 0.0 2.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 RNase H Zn_Tnp_IS1595 PF12760.2 KNZ74023.1 - 0.022 14.5 2.1 0.026 14.3 0.5 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain PTCB-BRCT PF12738.2 KNZ74024.1 - 1.2e-26 92.3 7.2 1.4e-16 60.1 0.1 5.3 6 0 0 6 6 6 3 twin BRCT domain BRCT PF00533.21 KNZ74024.1 - 7.8e-23 80.4 0.1 7.8e-08 32.3 0.0 6.3 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain DUF4653 PF15546.1 KNZ74025.1 - 0.063 12.5 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) RRM_6 PF14259.1 KNZ74026.1 - 2.8e-36 123.3 0.5 1.1e-10 41.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KNZ74026.1 - 2e-28 97.8 2.2 3.3e-09 36.2 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ74026.1 - 2.4e-15 56.1 0.0 0.0032 17.2 0.1 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KNZ74026.1 - 1.6e-05 24.7 0.1 0.046 13.5 0.1 2.6 2 0 0 2 2 2 2 RNA binding motif NID PF07292.8 KNZ74026.1 - 0.029 14.4 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) Glyco_hydro_81 PF03639.8 KNZ74027.1 - 3.5e-88 296.3 5.3 6.4e-88 295.5 3.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Fascin PF06268.8 KNZ74027.1 - 0.054 13.5 0.0 0.22 11.6 0.0 1.9 1 1 1 2 2 2 0 Fascin domain Metallophos PF00149.23 KNZ74029.1 - 6.2e-07 29.0 3.8 1.3e-06 27.9 2.6 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Clat_adaptor_s PF01217.15 KNZ74031.1 - 2.8e-12 46.5 0.0 4.4e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.20 KNZ74032.1 - 1.2e-15 57.4 0.0 8.7e-13 48.0 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74032.1 - 0.0016 17.5 0.0 0.12 11.3 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase NAD_binding_4 PF07993.7 KNZ74034.1 - 1.1e-34 119.5 0.0 1.6e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KNZ74034.1 - 9.8e-28 96.6 0.0 2e-26 92.3 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 KNZ74034.1 - 9.7e-07 28.4 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KNZ74034.1 - 0.00052 20.2 0.0 0.0015 18.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KNZ74034.1 - 0.0015 18.4 0.0 0.0063 16.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KNZ74034.1 - 0.0017 17.0 0.0 0.0034 16.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KNZ74034.1 - 0.0057 16.6 0.0 0.17 11.8 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KNZ74034.1 - 0.0062 16.2 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 KR domain AHS2 PF02626.10 KNZ74037.1 - 6.1e-61 206.0 0.0 1e-60 205.3 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 KNZ74037.1 - 9.9e-55 185.0 0.1 1.7e-54 184.3 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 KNZ74037.1 - 1.4e-41 142.2 0.0 2.4e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 KNZ74037.1 - 2.6e-31 107.9 0.0 5.3e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KNZ74037.1 - 2.5e-28 98.1 0.0 5.2e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KNZ74037.1 - 1.5e-10 41.1 0.1 3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KNZ74037.1 - 3.8e-06 26.4 0.0 7.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 KNZ74037.1 - 0.00037 19.3 0.0 0.28 9.8 0.0 2.4 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 KNZ74037.1 - 0.00037 20.0 0.0 0.0011 18.5 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.9 KNZ74037.1 - 0.0018 18.1 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KNZ74037.1 - 0.02 14.3 0.0 0.044 13.2 0.0 1.6 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp PF02222.17 KNZ74037.1 - 0.036 13.4 0.1 0.073 12.4 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain Utp12 PF04003.7 KNZ74037.1 - 0.079 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family Cro PF09048.5 KNZ74037.1 - 0.11 12.1 0.2 9.4 5.9 0.0 3.1 3 0 0 3 3 3 0 Cro WEMBL PF05701.6 KNZ74038.1 - 0.014 13.8 3.1 0.023 13.1 2.2 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Pkinase PF00069.20 KNZ74039.1 - 3.8e-15 55.7 0.0 1.8e-12 47.0 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74039.1 - 0.00063 18.8 0.0 0.067 12.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KNZ74040.1 - 3.3e-09 36.2 0.1 1.1e-06 28.0 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74040.1 - 0.0029 16.7 0.0 0.41 9.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase NIF PF03031.13 KNZ74042.1 - 3.8e-37 127.4 0.1 8.1e-37 126.3 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DASH_Dad1 PF08649.5 KNZ74042.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad1 DUF1323 PF07037.6 KNZ74042.1 - 0.035 14.2 0.1 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Putative transcription regulator (DUF1323) Metallophos PF00149.23 KNZ74044.1 - 1.1e-08 34.7 0.8 2.2e-08 33.7 0.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_8 PF13855.1 KNZ74045.1 - 0.0012 18.5 11.6 0.37 10.5 0.3 4.7 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 KNZ74045.1 - 0.028 14.0 6.8 0.49 10.0 0.3 4.0 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KNZ74045.1 - 0.59 10.3 10.4 0.1 12.7 0.6 4.6 4 1 0 4 4 4 0 Leucine Rich Repeat FCH PF00611.18 KNZ74046.1 - 9.8e-19 67.3 0.0 3.2e-18 65.7 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KNZ74046.1 - 1.1e-10 40.6 0.1 2.2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KNZ74046.1 - 2.8e-09 36.4 0.0 5.5e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KNZ74046.1 - 3.1e-05 23.3 0.0 5.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain zf-FPG_IleRS PF06827.9 KNZ74047.1 - 0.0012 18.4 0.5 0.0025 17.4 0.4 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.5 KNZ74047.1 - 0.0058 16.5 4.5 0.01 15.7 3.1 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_2 PF13240.1 KNZ74047.1 - 0.0067 15.8 2.4 0.042 13.3 0.2 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zf-CHY PF05495.7 KNZ74047.1 - 0.0093 16.1 3.0 0.013 15.6 2.0 1.2 1 0 0 1 1 1 1 CHY zinc finger HypA PF01155.14 KNZ74047.1 - 0.021 14.4 0.4 0.026 14.2 0.3 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C3HC4_3 PF13920.1 KNZ74047.1 - 0.039 13.6 1.3 0.06 13.0 0.9 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 KNZ74047.1 - 0.044 13.7 2.4 0.13 12.3 1.6 1.7 1 1 0 1 1 1 0 zinc-finger DRP PF06044.7 KNZ74047.1 - 0.11 11.5 0.2 0.12 11.3 0.2 1.2 1 0 0 1 1 1 0 Dam-replacing family Zn_Tnp_IS1595 PF12760.2 KNZ74047.1 - 0.13 12.0 2.3 5.7 6.8 0.1 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 KNZ74047.1 - 0.13 12.2 4.4 0.24 11.4 2.9 1.5 1 1 0 1 1 1 0 TFIIH C1-like domain LIM PF00412.17 KNZ74047.1 - 0.19 11.8 3.8 0.34 11.0 2.6 1.4 1 0 0 1 1 1 0 LIM domain DZR PF12773.2 KNZ74047.1 - 0.21 11.4 3.2 0.38 10.5 2.3 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 KNZ74047.1 - 0.35 10.1 3.1 0.85 8.9 2.1 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KNZ74047.1 - 0.47 10.1 7.3 7 6.4 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Evr1_Alr PF04777.8 KNZ74047.1 - 0.5 10.3 2.3 3.3 7.6 1.6 2.1 1 1 0 1 1 1 0 Erv1 / Alr family zinc-ribbons_6 PF07191.7 KNZ74047.1 - 0.53 10.1 3.3 1.8 8.4 2.3 1.8 1 1 0 1 1 1 0 zinc-ribbons zinc_ribbon_5 PF13719.1 KNZ74047.1 - 0.62 9.7 6.9 8 6.1 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2 PF00096.21 KNZ74047.1 - 0.92 9.9 6.0 1.6 9.2 0.8 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type TFIIS_C PF01096.13 KNZ74047.1 - 1.3 8.7 4.1 5.9 6.6 0.5 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-DNL PF05180.7 KNZ74047.1 - 4.4 7.0 6.9 31 4.3 4.8 2.2 1 1 0 1 1 1 0 DNL zinc finger zf-H2C2_2 PF13465.1 KNZ74047.1 - 7.4 7.0 9.9 4 7.8 1.1 2.5 3 0 0 3 3 2 0 Zinc-finger double domain Glyco_hydr_30_2 PF14587.1 KNZ74048.1 - 3.1e-16 59.2 0.0 2e-11 43.4 0.0 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_cc PF11790.3 KNZ74048.1 - 0.00081 18.8 0.0 0.0021 17.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core Glyco_hydro_30 PF02055.11 KNZ74048.1 - 0.0015 16.8 0.0 0.0042 15.3 0.0 1.6 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 VHL PF01847.11 KNZ74049.1 - 0.00079 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 von Hippel-Lindau disease tumour suppressor protein Glyco_hydro_81 PF03639.8 KNZ74050.1 - 4.1e-83 279.6 3.4 4.1e-83 279.6 2.4 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 81 Fascin PF06268.8 KNZ74050.1 - 0.02 14.9 0.0 0.086 12.9 0.0 2.0 1 1 0 1 1 1 0 Fascin domain p450 PF00067.17 KNZ74051.1 - 6.2e-07 28.3 0.3 0.0012 17.4 0.0 2.7 3 0 0 3 3 3 2 Cytochrome P450 E1-E2_ATPase PF00122.15 KNZ74052.1 - 2.1e-77 259.2 1.7 2.1e-77 259.2 1.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KNZ74052.1 - 2.9e-39 134.4 1.5 2.9e-39 134.4 1.0 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KNZ74052.1 - 6.2e-28 98.6 0.0 1.5e-27 97.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KNZ74052.1 - 3.6e-14 53.3 0.0 1.7e-13 51.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KNZ74052.1 - 9.1e-12 44.7 0.1 1.4e-10 40.9 0.0 2.5 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KNZ74052.1 - 3.2e-09 36.1 0.0 7.3e-09 34.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KNZ74052.1 - 1.4e-05 24.8 1.5 0.00054 19.6 0.5 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.7 KNZ74052.1 - 0.0011 18.5 1.5 0.0027 17.2 0.0 2.5 3 0 0 3 3 3 1 Positive regulator of sigma(E), RseC/MucC RhoGEF PF00621.15 KNZ74053.1 - 3e-33 115.1 0.0 1e-32 113.4 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain GCN5L1 PF06320.8 KNZ74053.1 - 0.11 12.3 2.7 0.46 10.3 1.8 2.0 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Aldo_ket_red PF00248.16 KNZ74054.1 - 2.7e-49 167.4 0.0 3.2e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Saw1 PF11561.3 KNZ74054.1 - 0.084 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Single strand annealing-weakened 1 DUF2513 PF10711.4 KNZ74059.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.4 1 1 0 1 1 1 0 Hypothetical protein (DUF2513) UbiA PF01040.13 KNZ74064.1 - 1.5e-06 27.6 0.2 1.8e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family tRNA-synt_1e PF01406.14 KNZ74064.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain zf-H2C2_2 PF13465.1 KNZ74065.1 - 6e-08 32.6 11.1 2.4e-07 30.7 0.3 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KNZ74065.1 - 2e-05 24.6 11.2 0.041 14.2 1.9 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ74065.1 - 0.00011 22.2 11.6 0.3 11.5 0.4 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KNZ74065.1 - 0.11 12.8 0.5 0.11 12.8 0.3 3.4 3 1 0 3 3 3 0 C2H2-type zinc-finger domain Fer2 PF00111.22 KNZ74066.1 - 3.9e-10 39.3 0.1 6e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FlgD_ig PF13860.1 KNZ74066.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 FlgD Ig-like domain adh_short PF00106.20 KNZ74067.1 - 1.7e-19 70.3 0.1 2.6e-19 69.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ74067.1 - 5.7e-07 29.3 0.1 8e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KNZ74067.1 - 9.5e-07 28.4 0.1 1.4e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KNZ74067.1 - 1.8e-06 27.9 0.0 2.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KNZ74067.1 - 0.00018 21.5 0.1 0.0024 17.8 0.1 2.1 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KNZ74067.1 - 0.06 12.5 0.1 0.083 12.1 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.14 KNZ74067.1 - 0.13 10.9 0.0 0.23 10.0 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Chromo PF00385.19 KNZ74069.1 - 1.5e-16 59.7 0.1 1.8e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 KNZ74070.1 - 0.01 16.3 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.1 KNZ74070.1 - 0.023 14.5 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-RVT PF13966.1 KNZ74074.1 - 0.045 14.0 0.5 0.071 13.4 0.3 1.3 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase NAP PF00956.13 KNZ74075.1 - 7.4e-79 264.3 3.7 7.4e-79 264.3 2.5 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) GvpG PF05120.7 KNZ74075.1 - 0.53 10.1 3.8 2.1 8.2 2.7 2.0 1 0 0 1 1 1 0 Gas vesicle protein G Cadherin_pro PF08758.6 KNZ74076.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Cadherin prodomain like LRR_8 PF13855.1 KNZ74077.1 - 9.6e-05 22.0 4.2 0.0069 16.1 0.2 3.5 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 KNZ74077.1 - 0.0092 15.5 9.3 1.5 8.5 1.7 4.6 3 2 0 3 3 3 2 Leucine Rich repeats (2 copies) P2 PF07194.6 KNZ74077.1 - 0.067 13.0 0.4 1 9.2 0.2 2.9 4 0 0 4 4 4 0 P2 response regulator binding domain Catalase-rel PF06628.7 KNZ74077.1 - 0.1 12.4 0.0 0.74 9.7 0.0 2.2 2 0 0 2 2 2 0 Catalase-related immune-responsive LRR_6 PF13516.1 KNZ74077.1 - 0.18 11.9 2.5 1.3e+02 3.1 0.0 5.1 6 0 0 6 6 6 0 Leucine Rich repeat MutL_C PF08676.6 KNZ74079.1 - 2.5e-23 82.2 0.2 7.1e-23 80.8 0.1 1.8 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KNZ74079.1 - 2.2e-18 65.8 0.0 4.6e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 KNZ74079.1 - 8.6e-13 47.9 0.0 2.4e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KNZ74079.1 - 7.9e-12 44.9 0.0 2.1e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyoxal_oxid_N PF07250.6 KNZ74080.1 - 1.3e-38 132.4 0.0 1.8e-34 118.8 0.0 3.6 3 1 0 3 3 3 3 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KNZ74080.1 - 9.1e-22 77.0 0.9 2.1e-21 75.8 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 KNZ74080.1 - 0.00061 19.5 8.0 0.34 10.7 0.1 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Pkinase PF00069.20 KNZ74081.1 - 1.4e-07 30.9 0.0 3.2e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KNZ74082.1 - 4.1e-05 23.4 0.0 0.00018 21.2 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ74082.1 - 0.0043 16.6 0.0 0.0053 16.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KNZ74082.1 - 0.066 12.5 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 KNZ74083.1 - 4.8e-08 32.4 0.0 1e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74083.1 - 0.045 12.8 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KNZ74084.1 - 3.1e-08 33.0 0.0 8.6e-08 31.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Chitin_synth_1 PF01644.12 KNZ74085.1 - 1.9e-63 213.1 0.2 3e-63 212.4 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KNZ74085.1 - 5e-28 96.6 0.2 1.2e-27 95.3 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KNZ74085.1 - 1.1e-24 86.7 0.1 1e-21 76.9 0.0 2.4 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KNZ74085.1 - 2.7e-10 40.2 0.0 2.7e-10 40.2 0.0 2.7 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KNZ74085.1 - 1.4e-06 28.2 0.0 5.2e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 RVT_1 PF00078.22 KNZ74086.1 - 0.068 12.5 0.0 0.068 12.5 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3680 PF12441.3 KNZ74088.1 - 0.085 12.7 0.0 0.67 9.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3680) CRC_subunit PF08624.5 KNZ74089.1 - 5.8e-39 133.1 0.0 1.1e-38 132.2 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit IgG_binding_B PF01378.12 KNZ74089.1 - 0.081 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 B domain AATase PF07247.7 KNZ74090.1 - 7.6e-05 21.4 0.0 0.00011 20.9 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KNZ74090.1 - 0.039 12.8 0.2 9.6 4.9 0.0 2.7 2 1 0 2 2 2 0 Condensation domain AMP-binding PF00501.23 KNZ74091.1 - 1.8e-63 214.4 0.9 1.1e-46 159.1 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KNZ74091.1 - 1.6e-06 28.9 0.2 7.1e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TPT PF03151.11 KNZ74092.1 - 2.7e-07 30.3 12.5 2.7e-07 30.3 8.6 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF4434 PF14488.1 KNZ74092.1 - 0.023 14.4 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Pkinase PF00069.20 KNZ74093.1 - 1.2e-65 221.2 0.0 2.1e-65 220.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74093.1 - 5.5e-38 130.5 0.0 5.9e-37 127.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ74093.1 - 4e-07 29.2 0.0 1.1e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ74093.1 - 0.00074 19.3 6.8 0.026 14.2 0.1 4.2 3 1 0 3 3 3 1 Phosphotransferase enzyme family Gon7 PF08738.5 KNZ74093.1 - 0.067 13.1 1.9 0.25 11.3 1.3 2.0 1 0 0 1 1 1 0 Gon7 family Peptidase_M20 PF01546.23 KNZ74094.1 - 8.3e-08 31.9 0.1 1.1e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KNZ74094.1 - 5e-05 23.0 0.0 0.00014 21.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain AAA_12 PF13087.1 KNZ74095.1 - 5e-57 192.5 0.0 2.3e-56 190.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KNZ74095.1 - 8.5e-55 185.8 0.0 1.8e-54 184.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KNZ74095.1 - 2.1e-10 40.5 0.0 0.036 13.5 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KNZ74095.1 - 6.2e-09 35.4 0.0 4.2e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KNZ74095.1 - 1.1e-07 31.5 0.0 0.00012 21.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 KNZ74095.1 - 8.2e-06 25.7 0.0 4.4e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KNZ74095.1 - 1.4e-05 25.2 0.0 0.0037 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 KNZ74095.1 - 0.002 17.4 0.0 0.0055 16.0 0.0 1.8 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 KNZ74095.1 - 0.002 18.1 0.1 0.0074 16.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 KNZ74095.1 - 0.003 16.6 0.1 0.073 12.0 0.0 2.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.1 KNZ74095.1 - 0.0042 17.1 0.0 0.033 14.3 0.0 2.5 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 KNZ74095.1 - 0.012 15.0 0.0 0.036 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KNZ74095.1 - 0.019 15.1 0.0 0.077 13.1 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KNZ74095.1 - 0.02 15.7 0.0 0.12 13.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain UvrD_C PF13361.1 KNZ74095.1 - 0.047 13.1 0.1 0.1 12.0 0.1 1.7 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_23 PF13476.1 KNZ74095.1 - 0.077 13.3 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 KNZ74095.1 - 0.15 10.9 0.0 15 4.3 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Arch_ATPase PF01637.13 KNZ74096.1 - 5.6e-13 49.1 0.0 9.7e-07 28.7 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase AAA_16 PF13191.1 KNZ74096.1 - 2.8e-07 30.7 0.1 9.3e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KNZ74096.1 - 6.3e-06 26.3 0.0 0.0066 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA12 PF10443.4 KNZ74096.1 - 0.0015 17.0 0.0 0.0027 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA12 protein AAA PF00004.24 KNZ74096.1 - 0.0018 18.4 0.0 0.38 10.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KNZ74096.1 - 0.013 15.3 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain zf-C3HC4_2 PF13923.1 KNZ74097.1 - 1e-07 31.8 7.1 1e-07 31.8 5.0 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNZ74097.1 - 8.8e-07 28.5 6.0 8.8e-07 28.5 4.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ74097.1 - 1.4e-06 28.0 8.6 1.4e-06 28.0 6.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 KNZ74097.1 - 4.1e-06 26.5 2.1 4.1e-06 26.5 1.5 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KNZ74097.1 - 1.5e-05 24.5 7.3 1.5e-05 24.5 5.1 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KNZ74097.1 - 2.6e-05 23.7 6.9 2.6e-05 23.7 4.8 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KNZ74097.1 - 0.0048 16.6 0.2 0.0048 16.6 0.2 2.5 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KNZ74097.1 - 0.012 15.3 3.8 0.012 15.3 1.1 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-MIZ PF02891.15 KNZ74097.1 - 5.6 6.5 10.3 0.68 9.4 2.0 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger HAMP PF00672.20 KNZ74098.1 - 4.7e-49 164.4 22.2 9.7e-09 35.2 0.0 8.2 8 1 0 8 8 8 7 HAMP domain HATPase_c PF02518.21 KNZ74098.1 - 1e-27 96.0 0.1 3.7e-27 94.2 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KNZ74098.1 - 1.4e-22 79.8 0.1 4.2e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KNZ74098.1 - 9e-18 64.0 1.0 5.3e-17 61.5 0.7 2.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain WXG100 PF06013.7 KNZ74098.1 - 0.13 12.3 12.6 4.4 7.3 0.1 6.5 6 2 0 7 7 7 0 Proteins of 100 residues with WXG Syntaxin PF00804.20 KNZ74098.1 - 0.52 10.4 7.2 4.8 7.4 0.2 4.7 4 2 0 4 4 4 0 Syntaxin NAAA-beta PF15508.1 KNZ74098.1 - 0.67 10.3 3.1 14 6.0 0.1 4.6 6 1 0 6 6 6 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase AcylCoA_dehyd_C PF12186.3 KNZ74098.1 - 1.2 8.9 13.3 34 4.3 0.0 6.5 7 1 1 8 8 8 0 Acyl-CoA dehydrogenase C terminal DUF2365 PF10157.4 KNZ74098.1 - 4.2 7.2 20.7 24 4.7 0.0 7.6 5 3 2 7 7 7 0 Uncharacterized conserved protein (DUF2365) HNH_2 PF13391.1 KNZ74099.1 - 2.2e-07 30.5 0.1 6.1e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease RNase_H PF00075.19 KNZ74100.1 - 3.2e-15 56.6 0.0 3.4e-15 56.5 0.0 1.0 1 0 0 1 1 1 1 RNase H Glyco_hydro_3_C PF01915.17 KNZ74101.1 - 4.1e-42 144.2 0.0 5.9e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Phage_lysis PF03245.8 KNZ74102.1 - 0.016 15.1 0.2 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein DUF3328 PF11807.3 KNZ74103.1 - 4.4e-23 82.1 3.0 5e-23 81.9 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) But2 PF09792.4 KNZ74104.1 - 0.0017 18.1 0.1 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain PIF1 PF05970.9 KNZ74105.1 - 6.4e-09 35.2 0.0 6.7e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Rad1 PF02144.11 KNZ74107.1 - 3.7e-75 252.2 0.0 4.2e-75 252.0 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 HpaB_N PF11794.3 KNZ74108.1 - 0.047 13.0 0.1 0.06 12.7 0.1 1.1 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Asp_protease_2 PF13650.1 KNZ74110.1 - 0.00033 21.1 0.0 0.0006 20.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ74110.1 - 0.015 14.9 0.5 0.18 11.3 0.1 2.4 1 1 1 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.1 KNZ74110.1 - 0.08 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KNZ74111.1 - 0.061 13.2 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Cellulase PF00150.13 KNZ74112.1 - 3.7e-48 164.1 0.1 4.9e-48 163.7 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KNZ74112.1 - 4.3e-08 32.6 2.5 1e-07 31.4 1.7 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Complex1_LYR PF05347.10 KNZ74113.1 - 0.0018 18.0 1.0 0.0037 17.0 0.7 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KNZ74113.1 - 0.0074 16.4 0.8 0.014 15.5 0.5 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Sec8_exocyst PF04048.9 KNZ74114.1 - 4e-26 91.3 0.2 4.1e-25 88.0 0.1 2.2 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KNZ74114.1 - 2.4e-05 23.4 0.4 4.9e-05 22.3 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2305 PF10230.4 KNZ74115.1 - 2.3e-49 168.1 0.0 2.7e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KNZ74115.1 - 6.7e-09 35.9 1.9 8.7e-09 35.5 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ74115.1 - 8.3e-05 22.3 0.3 0.00012 21.8 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KNZ74115.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold SNF2_N PF00176.18 KNZ74116.1 - 3.6e-58 196.7 0.0 5.3e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 KNZ74116.1 - 2.4e-22 79.1 0.0 5.3e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 KNZ74116.1 - 6.9e-13 48.2 0.0 1.9e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-PHD-like PF15446.1 KNZ74116.1 - 1.1e-05 24.7 4.0 1.1e-05 24.7 2.8 2.9 2 2 0 2 2 2 1 PHD/FYVE-zinc-finger like domain DEAD PF00270.24 KNZ74116.1 - 2.9e-05 23.6 0.0 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Chromo PF00385.19 KNZ74116.1 - 0.017 14.7 7.6 0.14 11.8 0.1 3.2 3 0 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain AAA_22 PF13401.1 KNZ74116.1 - 0.043 13.9 0.0 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KNZ74116.1 - 0.21 10.9 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ribonucleas_3_3 PF14622.1 KNZ74117.1 - 2e-08 34.2 0.0 3.1e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 KNZ74117.1 - 2e-07 31.4 0.0 5.2e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 KNZ74117.1 - 0.013 15.9 0.0 0.022 15.1 0.0 1.4 1 1 0 1 1 1 0 Ribonuclease III domain Pkinase PF00069.20 KNZ74118.1 - 1.2e-54 185.2 0.0 1.6e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74118.1 - 9e-29 100.3 0.0 1.2e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KNZ74118.1 - 0.0031 17.6 0.0 0.0066 16.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KNZ74118.1 - 0.0082 15.1 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Esterase PF00756.15 KNZ74119.1 - 3e-44 151.3 0.0 3.6e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KNZ74119.1 - 0.00012 21.9 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KNZ74119.1 - 0.0014 17.8 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KNZ74119.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 KNZ74119.1 - 0.035 13.0 0.0 0.063 12.1 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme p450 PF00067.17 KNZ74120.1 - 3.7e-24 85.0 0.0 7.4e-24 84.0 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 SPATA25 PF15218.1 KNZ74121.1 - 0.095 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 Kelch_3 PF13415.1 KNZ74122.1 - 1.9e-39 132.9 11.7 3.4e-08 33.4 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KNZ74122.1 - 2e-35 120.2 9.6 2.9e-06 26.9 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KNZ74122.1 - 1.1e-33 114.6 6.9 8.2e-06 25.6 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 KNZ74122.1 - 6.6e-32 108.8 3.5 2e-06 27.2 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KNZ74122.1 - 1.2e-29 101.1 6.7 1.9e-06 27.7 0.3 6.3 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KNZ74122.1 - 1.6e-19 68.8 10.9 0.0039 16.9 0.1 6.5 6 0 0 6 6 6 5 Kelch motif TPR_MLP1_2 PF07926.7 KNZ74122.1 - 0.0016 18.2 16.2 0.0016 18.2 11.2 6.5 4 2 2 6 6 6 2 TPR/MLP1/MLP2-like protein DUF2779 PF11074.3 KNZ74122.1 - 0.67 10.0 2.2 0.75 9.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) Vac_Fusion PF02346.11 KNZ74122.1 - 7.6 6.0 11.0 5.9 6.3 0.1 3.6 4 0 0 4 4 4 0 Chordopoxvirus fusion protein ABC_membrane_2 PF06472.10 KNZ74123.1 - 3.1e-80 269.3 0.9 5e-80 268.6 0.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KNZ74123.1 - 3e-16 59.9 0.0 6.4e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 KNZ74123.1 - 0.0062 16.2 1.2 0.2 11.4 0.1 2.8 3 0 0 3 3 3 1 Part of AAA domain Sigma54_activ_2 PF14532.1 KNZ74123.1 - 0.042 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain SMC_N PF02463.14 KNZ74123.1 - 0.043 13.0 0.0 3.3 6.8 0.0 2.1 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.16 KNZ74123.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI S1 PF00575.18 KNZ74124.1 - 1e-59 198.5 24.2 5.8e-13 48.7 0.1 10.6 10 0 0 10 10 10 9 S1 RNA binding domain TPR_14 PF13428.1 KNZ74124.1 - 1.5e-06 28.2 0.0 2.3 9.1 0.0 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ74124.1 - 2e-06 28.3 0.0 0.12 13.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ74124.1 - 2.2e-05 24.2 0.8 0.25 11.3 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ74124.1 - 4e-05 23.8 0.9 2 8.8 0.1 4.4 3 1 2 5 5 5 3 Tetratricopeptide repeat RNA_pol_Rbc25 PF08292.7 KNZ74124.1 - 0.011 15.8 4.3 3.7 7.7 0.0 4.8 5 0 0 5 5 5 0 RNA polymerase III subunit Rpc25 TPR_2 PF07719.12 KNZ74124.1 - 0.031 14.1 1.5 13 5.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Suf PF05843.9 KNZ74124.1 - 0.19 11.4 10.1 0.36 10.5 0.8 4.0 2 1 0 3 3 3 0 Suppressor of forked protein (Suf) zf-met PF12874.2 KNZ74125.1 - 1.5e-06 28.1 1.2 2.7e-06 27.3 0.6 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 KNZ74125.1 - 0.017 14.3 0.6 0.031 13.5 0.4 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like MRP-S25 PF13741.1 KNZ74126.1 - 5.3e-39 134.0 8.4 2.2e-37 128.7 5.8 2.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 PCI PF01399.22 KNZ74127.1 - 2.5e-18 66.3 0.0 8.5e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 PCI domain Drc1-Sld2 PF11719.3 KNZ74129.1 - 3e-12 46.3 29.3 6e-10 38.7 20.3 2.8 1 1 0 1 1 1 1 DNA replication and checkpoint protein Pal1 PF08316.6 KNZ74132.1 - 0.023 15.1 0.8 0.049 14.0 0.0 1.9 2 0 0 2 2 2 0 Pal1 cell morphology protein AMP-binding PF00501.23 KNZ74133.1 - 5.1e-69 232.6 0.0 9.2e-69 231.8 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KNZ74133.1 - 1.5e-12 48.2 0.1 4.2e-12 46.8 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PIF1 PF05970.9 KNZ74134.1 - 2.8e-38 131.8 0.4 5.3e-38 130.8 0.0 1.5 2 0 0 2 2 2 1 PIF1-like helicase ResIII PF04851.10 KNZ74134.1 - 0.0037 17.1 0.0 0.009 15.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KNZ74134.1 - 0.008 16.3 0.1 0.15 12.2 0.0 2.7 3 1 0 3 3 3 1 RNA helicase AAA_16 PF13191.1 KNZ74134.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 KNZ74134.1 - 0.026 14.1 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sec7_N PF12783.2 KNZ74134.1 - 0.031 13.6 0.1 0.35 10.2 0.0 2.1 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal AAA_17 PF13207.1 KNZ74134.1 - 0.035 14.9 0.2 0.13 13.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KNZ74134.1 - 0.08 12.4 0.1 0.19 11.2 0.1 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KNZ74134.1 - 0.097 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain EcoEI_R_C PF08463.5 KNZ74134.1 - 0.098 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 EcoEI R protein C-terminal PhoH PF02562.11 KNZ74134.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Med7 PF05983.6 KNZ74135.1 - 5.8e-28 97.7 0.0 3.7e-27 95.0 0.0 2.0 1 1 0 1 1 1 1 MED7 protein Fez1 PF06818.10 KNZ74135.1 - 0.077 13.0 1.7 0.12 12.4 1.2 1.2 1 0 0 1 1 1 0 Fez1 BCL_N PF04714.8 KNZ74136.1 - 0.0018 17.8 0.2 0.0032 17.0 0.2 1.4 1 0 0 1 1 1 1 BCL7, N-terminal conserver region GARS_A PF01071.14 KNZ74140.1 - 1e-78 263.3 0.0 1.5e-78 262.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KNZ74140.1 - 1.1e-33 115.6 0.0 2.3e-32 111.4 0.0 2.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 KNZ74140.1 - 5.8e-29 100.1 0.1 1.2e-28 99.0 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS_C PF02769.17 KNZ74140.1 - 1.6e-28 99.6 0.0 3.1e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KNZ74140.1 - 1.6e-16 60.3 0.6 1.6e-16 60.3 0.4 3.6 4 0 0 4 4 4 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KNZ74140.1 - 3.6e-08 33.3 0.0 2.2e-07 30.8 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KNZ74140.1 - 9.5e-06 24.5 0.0 1.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 KNZ74140.1 - 5.4e-05 22.5 0.1 9e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 KNZ74140.1 - 0.037 13.8 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain RimK PF08443.6 KNZ74140.1 - 0.18 11.2 0.1 1.8 7.9 0.0 2.2 1 1 1 2 2 2 0 RimK-like ATP-grasp domain Ank PF00023.25 KNZ74141.1 - 5.9e-09 35.3 0.1 3.2e-06 26.6 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KNZ74141.1 - 1.8e-08 34.6 0.0 3.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KNZ74141.1 - 1.5e-06 28.2 0.0 1.1e-05 25.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-CCCH_2 PF14608.1 KNZ74141.1 - 1.7e-06 27.7 15.1 8.3e-05 22.4 3.4 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type Ank_3 PF13606.1 KNZ74141.1 - 1.4e-05 24.8 0.0 0.00047 20.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 KNZ74141.1 - 0.00016 22.1 0.0 0.00027 21.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-CCCH PF00642.19 KNZ74141.1 - 0.00029 20.4 12.1 0.041 13.5 2.6 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NAD_Gly3P_dh_C PF07479.9 KNZ74142.1 - 2.5e-48 163.6 0.3 3.5e-48 163.1 0.2 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 KNZ74142.1 - 6.9e-23 81.1 0.0 1.3e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Syntaxin PF00804.20 KNZ74143.1 - 2.3e-15 56.6 5.7 2.3e-15 56.6 3.9 2.6 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 KNZ74143.1 - 8.9e-15 54.1 0.7 8.9e-15 54.1 0.5 2.4 2 0 0 2 2 2 1 SNARE domain Sed5p PF11416.3 KNZ74143.1 - 0.0028 17.0 0.0 0.014 14.7 0.0 2.3 1 0 0 1 1 1 1 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 KNZ74143.1 - 0.0056 16.4 4.4 0.0088 15.8 0.2 3.0 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus zf-C4H2 PF10146.4 KNZ74143.1 - 0.012 15.6 3.1 2.4 8.0 0.1 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Osmo_CC PF08946.5 KNZ74143.1 - 0.48 10.5 11.2 0.18 11.8 1.5 3.6 4 0 0 4 4 4 0 Osmosensory transporter coiled coil DUF1664 PF07889.7 KNZ74143.1 - 0.62 9.8 9.0 0.76 9.5 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 KNZ74143.1 - 1.1 9.3 9.1 1.5 9.0 0.2 3.3 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_N PF02465.13 KNZ74143.1 - 2.1 8.7 10.1 0.35 11.2 0.4 3.3 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus SlyX PF04102.7 KNZ74143.1 - 2.1 8.7 6.7 5 7.5 0.8 3.0 2 1 0 2 2 2 0 SlyX Spectrin PF00435.16 KNZ74143.1 - 3 8.1 7.9 0.56 10.5 0.4 3.0 2 1 1 3 3 3 0 Spectrin repeat FlxA PF14282.1 KNZ74143.1 - 7.3 6.5 23.0 0.1 12.5 4.7 2.9 2 1 0 2 2 2 0 FlxA-like protein Atg14 PF10186.4 KNZ74143.1 - 7.8 5.3 14.2 8.2 5.2 1.8 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 RRM_6 PF14259.1 KNZ74144.1 - 1.5e-09 37.6 0.0 2.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KNZ74144.1 - 5.5e-08 32.3 0.0 1.5e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAPEG PF01124.13 KNZ74146.1 - 3.3e-19 68.7 0.2 4.1e-19 68.4 0.2 1.1 1 0 0 1 1 1 1 MAPEG family SpoU_methylas_C PF12105.3 KNZ74146.1 - 0.15 11.6 0.0 0.59 9.7 0.0 1.9 2 1 0 2 2 2 0 SpoU, rRNA methylase, C-terminal DDE_3 PF13358.1 KNZ74147.1 - 1.2e-06 28.3 0.0 8.1e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease CENP-C_C PF11699.3 KNZ74148.1 - 8.8e-25 86.5 0.1 1.4e-24 85.8 0.1 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 KNZ74148.1 - 0.00029 20.2 0.0 0.00051 19.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain PmbA_TldD PF01523.11 KNZ74148.1 - 0.029 13.6 0.6 0.058 12.6 0.4 1.4 1 0 0 1 1 1 0 Putative modulator of DNA gyrase AraC_binding PF02311.14 KNZ74148.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain tRNA_Me_trans PF03054.11 KNZ74149.1 - 1.9e-113 378.6 0.0 2.2e-113 378.4 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 KNZ74149.1 - 0.0057 15.5 0.1 2.2 7.0 0.0 2.4 2 1 0 2 2 2 2 NAD synthase ThiI PF02568.9 KNZ74149.1 - 0.17 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) UBN2_2 PF14227.1 KNZ74150.1 - 6.3e-07 28.9 0.2 1.1e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ74150.1 - 2.5e-06 27.2 0.8 4.7e-06 26.3 0.5 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KNZ74150.1 - 0.096 12.6 0.3 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle WD40 PF00400.27 KNZ74152.1 - 1.7e-21 75.2 9.7 3.2e-08 33.1 0.4 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KNZ74152.1 - 1.2e-17 63.5 0.0 2.9e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex PA28_beta PF02252.13 KNZ74153.1 - 3.7e-39 133.5 0.4 5.4e-39 133.0 0.2 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 KNZ74153.1 - 0.009 16.1 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit IMS PF00817.15 KNZ74153.1 - 0.033 14.0 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 impB/mucB/samB family Phage-A118_gp45 PF10653.4 KNZ74153.1 - 0.043 13.6 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein gp45 of Bacteriophage A118 DUF3591 PF12157.3 KNZ74154.1 - 8.1e-176 584.8 0.3 1.4e-175 584.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 KNZ74154.1 - 0.00011 21.7 2.0 0.00025 20.6 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF1525 PF07511.6 KNZ74154.1 - 5.4 7.0 7.2 0.24 11.3 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1525) zf-C2H2 PF00096.21 KNZ74155.1 - 1.2e-06 28.4 25.7 2.3e-05 24.4 1.4 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KNZ74155.1 - 3.8e-05 23.7 4.1 3.8e-05 23.7 2.8 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 KNZ74155.1 - 0.0011 19.0 0.2 0.0011 19.0 0.1 4.5 4 1 1 5 5 5 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KNZ74155.1 - 0.0013 18.8 0.3 0.0013 18.8 0.2 3.6 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KNZ74155.1 - 5 7.7 25.9 0.038 14.3 1.8 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger EF-hand_6 PF13405.1 KNZ74156.1 - 4.5e-12 44.7 2.5 2.7e-06 26.7 0.2 3.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KNZ74156.1 - 1.6e-11 44.1 4.8 9.4e-06 25.6 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KNZ74156.1 - 9.9e-10 37.0 6.8 1.5e-05 23.9 0.3 4.0 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.1 KNZ74156.1 - 0.00054 19.8 0.0 0.79 9.6 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KNZ74156.1 - 0.0025 17.0 4.0 0.045 13.1 0.4 2.8 3 0 0 3 3 3 1 EF hand RRM_1 PF00076.17 KNZ74156.1 - 0.038 13.6 0.4 0.48 10.1 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EFhand_Ca_insen PF08726.5 KNZ74156.1 - 0.058 13.3 0.8 0.36 10.8 0.0 2.3 2 1 0 2 2 2 0 Ca2+ insensitive EF hand EF-hand_8 PF13833.1 KNZ74156.1 - 4.2 7.0 8.3 5.2 6.7 0.1 3.6 3 2 2 5 5 5 0 EF-hand domain pair adh_short PF00106.20 KNZ74157.1 - 5.6e-24 84.9 0.0 7.7e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ74157.1 - 3.7e-17 62.8 0.0 4.4e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KNZ74157.1 - 4e-07 29.4 0.0 1.2e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 KNZ74157.1 - 8.2e-07 28.8 0.0 2.3e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KNZ74157.1 - 3e-05 23.5 0.0 5.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ74157.1 - 3.5e-05 23.9 0.1 4.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KNZ74157.1 - 0.0041 16.0 0.0 0.0064 15.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.10 KNZ74157.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PI-PLC-X PF00388.14 KNZ74158.1 - 0.0032 16.8 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Utp11 PF03998.8 KNZ74159.1 - 5.9e-55 186.7 28.0 1.2e-54 185.7 19.4 1.5 1 1 0 1 1 1 1 Utp11 protein DsrD PF08679.6 KNZ74159.1 - 0.31 11.0 3.1 0.43 10.6 0.0 2.5 3 0 0 3 3 3 0 Dissimilatory sulfite reductase D (DsrD) FAR1 PF03101.10 KNZ74160.1 - 0.048 14.1 0.4 0.086 13.3 0.3 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain VHS PF00790.14 KNZ74161.1 - 8.3e-30 103.2 0.0 1.8e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KNZ74161.1 - 5.5e-08 32.6 1.1 1.5e-07 31.2 0.5 1.9 2 0 0 2 2 2 1 GAT domain Penicillinase_R PF03965.11 KNZ74161.1 - 0.0083 16.2 0.6 0.33 11.0 0.0 2.6 2 0 0 2 2 2 1 Penicillinase repressor tRNA-synt_2b PF00587.20 KNZ74162.1 - 1.5e-25 89.7 0.0 2.6e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KNZ74162.1 - 9e-08 32.0 0.8 1.5e-07 31.3 0.5 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Lzipper-MIP1 PF14389.1 KNZ74162.1 - 0.15 12.1 0.3 0.38 10.8 0.2 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Rep_fac_C PF08542.6 KNZ74163.1 - 2.8e-21 75.2 0.0 6.9e-21 74.0 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 KNZ74163.1 - 6.7e-12 45.7 0.0 1.2e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KNZ74163.1 - 1.4e-11 44.3 0.0 3.8e-10 39.6 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KNZ74163.1 - 1.2e-07 31.6 0.0 2.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ74163.1 - 2.2e-06 27.7 0.0 3.1e-05 24.0 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KNZ74163.1 - 4.3e-06 26.8 0.1 0.0034 17.5 0.0 2.5 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 KNZ74163.1 - 1.5e-05 24.1 0.0 3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 KNZ74163.1 - 2.7e-05 23.7 0.0 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KNZ74163.1 - 9.3e-05 22.0 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 KNZ74163.1 - 0.00031 19.5 0.0 0.061 12.0 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 KNZ74163.1 - 0.00084 18.8 0.1 0.19 11.1 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain NTPase_1 PF03266.10 KNZ74163.1 - 0.0025 17.5 0.2 0.01 15.5 0.1 1.9 1 1 1 2 2 2 1 NTPase Mg_chelatase PF01078.16 KNZ74163.1 - 0.0032 16.6 0.0 0.031 13.4 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ArgK PF03308.11 KNZ74163.1 - 0.0034 16.2 0.0 0.011 14.5 0.0 1.6 1 1 1 2 2 2 1 ArgK protein AAA_19 PF13245.1 KNZ74163.1 - 0.0067 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KNZ74163.1 - 0.0089 16.3 0.1 0.026 14.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KNZ74163.1 - 0.015 14.8 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KNZ74163.1 - 0.027 14.6 0.1 0.17 12.0 0.1 2.4 1 1 0 1 1 1 0 RNA helicase DEAD PF00270.24 KNZ74163.1 - 0.047 13.1 0.1 0.91 8.9 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 KNZ74163.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family SRP54 PF00448.17 KNZ74163.1 - 0.075 12.4 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 KNZ74163.1 - 0.14 12.9 0.5 0.39 11.5 0.4 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KNZ74163.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter PIF1 PF05970.9 KNZ74165.1 - 1.8e-15 56.8 0.0 2.4e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 KNZ74165.1 - 0.0029 17.4 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 KNZ74165.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 KNZ74165.1 - 0.048 13.2 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KNZ74165.1 - 0.069 12.6 0.1 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.6 KNZ74165.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Torsin DUF1537 PF07005.6 KNZ74165.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF1537 DinB_2 PF12867.2 KNZ74166.1 - 4.8e-05 23.7 0.6 6.1e-05 23.3 0.4 1.1 1 0 0 1 1 1 1 DinB superfamily COG6 PF06419.6 KNZ74166.1 - 0.13 10.4 0.0 0.14 10.2 0.0 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Chromo PF00385.19 KNZ74167.1 - 5.4e-06 25.9 0.1 1.5e-05 24.5 0.0 1.8 1 1 1 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KNZ74167.1 - 0.0041 16.9 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 Chromo shadow domain 4HBT_3 PF13622.1 KNZ74168.1 - 2.9e-33 115.6 0.3 1.3e-32 113.6 0.2 1.8 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KNZ74168.1 - 1.2e-18 67.0 0.1 8e-14 51.3 0.0 3.4 2 2 0 2 2 2 2 Acyl-CoA thioesterase Ribosomal_S27e PF01667.12 KNZ74169.1 - 1.8e-22 78.6 5.2 2.1e-22 78.3 3.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF2826 PF11442.3 KNZ74169.1 - 0.12 12.0 0.5 0.12 12.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) DUF3133 PF11331.3 KNZ74169.1 - 0.16 11.5 7.1 2.1 7.9 3.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) zf-C3HC4_3 PF13920.1 KNZ74169.1 - 0.49 10.1 3.7 0.74 9.5 2.5 1.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BTG PF07742.7 KNZ74170.1 - 4.8e-08 32.5 0.0 1.7e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 BTG family RAP1 PF07218.6 KNZ74170.1 - 0.61 8.1 6.1 0.79 7.7 4.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BATS PF06968.8 KNZ74171.1 - 3.3e-28 97.3 0.0 7.3e-28 96.2 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KNZ74171.1 - 3.9e-18 66.1 0.0 6.8e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily RNase_T PF00929.19 KNZ74172.1 - 4.8e-12 46.4 0.0 8.3e-12 45.6 0.0 1.4 1 1 0 1 1 1 1 Exonuclease AAA_16 PF13191.1 KNZ74175.1 - 0.069 13.1 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.1 KNZ74177.1 - 0.0081 16.1 0.0 1.6 8.6 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KNZ74177.1 - 0.076 13.1 0.1 13 5.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain Prp18 PF02840.10 KNZ74178.1 - 0.16 11.7 0.2 0.31 10.8 0.2 1.5 1 0 0 1 1 1 0 Prp18 domain RBDV_coat PF06593.6 KNZ74180.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Raspberry bushy dwarf virus coat protein MFS_1 PF07690.11 KNZ74181.1 - 0.00033 19.5 15.7 0.00057 18.6 10.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Lyase_1 PF00206.15 KNZ74182.1 - 1.4e-95 320.0 0.0 3.4e-95 318.8 0.0 1.6 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.1 KNZ74182.1 - 3.3e-23 81.5 0.4 3.6e-17 62.1 0.0 2.6 2 0 0 2 2 2 2 Argininosuccinate lyase C-terminal SNARE PF05739.14 KNZ74183.1 - 3.1e-14 52.3 1.4 3.1e-14 52.3 1.0 2.2 2 1 1 3 3 3 1 SNARE domain Syntaxin PF00804.20 KNZ74183.1 - 1.2e-13 51.1 6.7 2.3e-12 46.9 1.2 2.4 2 0 0 2 2 2 2 Syntaxin MCPsignal PF00015.16 KNZ74183.1 - 0.0036 16.8 2.3 0.0036 16.8 1.6 2.3 1 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.1 KNZ74183.1 - 0.018 15.0 6.1 0.018 15.0 4.2 2.2 2 0 0 2 2 2 0 Syntaxin-like protein VitD-bind_III PF09164.5 KNZ74183.1 - 0.028 14.0 0.7 0.13 11.8 0.1 2.2 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Spectrin PF00435.16 KNZ74183.1 - 0.042 14.1 4.7 3.1 8.1 0.0 3.0 3 0 0 3 3 3 0 Spectrin repeat DUF805 PF05656.9 KNZ74183.1 - 0.079 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF4463 PF14703.1 KNZ74183.1 - 0.12 12.8 0.5 0.86 10.1 0.1 2.4 2 2 0 2 2 2 0 Domain of unknown function (DUF4463) Internalin_N PF12354.3 KNZ74183.1 - 0.47 10.0 3.3 0.36 10.4 0.2 2.0 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal Spc7 PF08317.6 KNZ74183.1 - 0.79 8.3 10.4 2.1 6.8 2.6 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein WXG100 PF06013.7 KNZ74183.1 - 1.5 8.8 10.1 2.3 8.2 0.1 3.9 2 1 1 3 3 3 0 Proteins of 100 residues with WXG NAP PF00956.13 KNZ74183.1 - 2.8 6.9 7.6 5.5 6.0 3.6 2.4 1 1 1 2 2 2 0 Nucleosome assembly protein (NAP) BLOC1_2 PF10046.4 KNZ74183.1 - 4.5 7.4 8.6 4.7 7.4 0.3 3.3 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4094 PF13334.1 KNZ74183.1 - 4.9 7.5 7.6 3.4 8.1 0.1 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4094) V-SNARE PF05008.10 KNZ74183.1 - 6 7.1 13.8 0.61 10.2 0.3 3.7 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus zf-AN1 PF01428.11 KNZ74184.1 - 2.1e-08 33.8 14.2 8.1e-08 32.0 9.9 1.9 1 1 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.16 KNZ74184.1 - 0.047 13.5 10.6 0.056 13.3 7.0 1.4 1 1 0 1 1 1 0 IBR domain zf-RING_4 PF14570.1 KNZ74184.1 - 5.7 6.6 7.7 1.1 8.8 2.7 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Aminotran_1_2 PF00155.16 KNZ74185.1 - 2.1e-87 293.4 0.0 2.3e-87 293.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HEAT PF02985.17 KNZ74186.1 - 1.9e-14 52.3 19.1 0.0027 17.6 0.1 10.0 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.1 KNZ74186.1 - 7e-12 45.4 17.5 2.9e-05 24.2 0.0 7.1 6 1 1 7 7 7 4 HEAT repeats Adaptin_N PF01602.15 KNZ74186.1 - 0.00037 18.9 0.0 0.0011 17.3 0.0 1.7 2 0 0 2 2 2 1 Adaptin N terminal region HEAT_EZ PF13513.1 KNZ74186.1 - 0.014 15.8 19.0 0.87 10.1 0.2 6.9 5 1 1 6 6 6 0 HEAT-like repeat V-ATPase_H_N PF03224.9 KNZ74186.1 - 0.028 13.5 0.1 0.062 12.4 0.1 1.5 2 0 0 2 2 2 0 V-ATPase subunit H Lig_chan PF00060.21 KNZ74186.1 - 0.17 11.6 0.1 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Ligand-gated ion channel MARVEL PF01284.18 KNZ74187.1 - 0.00062 19.6 15.2 0.0011 18.7 10.5 1.4 1 0 0 1 1 1 1 Membrane-associating domain Ion_trans PF00520.26 KNZ74189.1 - 0.085 12.0 0.0 0.088 12.0 0.0 1.1 1 0 0 1 1 1 0 Ion transport protein FUN14 PF04930.10 KNZ74190.1 - 6.3e-17 61.6 0.1 8.1e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 FUN14 family DUF4341 PF14241.1 KNZ74190.1 - 0.79 9.4 4.1 0.9 9.2 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4341) Nol1_Nop2_Fmu PF01189.12 KNZ74191.1 - 9e-102 340.2 0.0 1.2e-101 339.8 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family Met_10 PF02475.11 KNZ74191.1 - 0.00045 19.8 0.0 0.00085 18.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.14 KNZ74191.1 - 0.0038 16.7 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KNZ74191.1 - 0.0043 16.6 0.0 0.008 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KNZ74191.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.7 KNZ74191.1 - 0.046 13.2 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Hexapep PF00132.19 KNZ74192.1 - 2e-11 42.8 16.6 0.0004 19.7 0.6 4.2 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 KNZ74192.1 - 2.7e-08 33.4 0.0 4.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 KNZ74192.1 - 9.8e-07 28.2 12.9 0.00094 18.6 1.6 4.0 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase W2 PF02020.13 KNZ74192.1 - 2.5e-06 27.3 1.5 1.4e-05 24.9 1.0 2.3 1 1 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transf_3 PF12804.2 KNZ74192.1 - 0.00026 21.1 0.0 0.00041 20.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 KNZ74192.1 - 0.0078 14.8 2.0 0.018 13.6 1.2 1.6 1 1 0 1 1 1 1 L-fucokinase Put_DNA-bind_N PF06971.8 KNZ74192.1 - 0.084 12.6 1.1 6.8 6.5 0.0 2.9 3 0 0 3 3 3 0 Putative DNA-binding protein N-terminus Abhydrolase_5 PF12695.2 KNZ74193.1 - 4.3e-09 36.2 0.0 6.3e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KNZ74193.1 - 2.6e-08 33.6 0.0 4.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KNZ74193.1 - 0.014 14.1 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family Aminotran_5 PF00266.14 KNZ74194.1 - 1.7e-10 40.2 0.0 2.4e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V FAD_binding_3 PF01494.14 KNZ74195.1 - 1.5e-21 76.9 0.0 3.3e-21 75.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KNZ74195.1 - 2.6e-06 26.5 0.0 0.00016 20.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KNZ74195.1 - 3.2e-06 27.4 0.0 9.2e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KNZ74195.1 - 1.4e-05 25.0 0.1 6.7e-05 22.8 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ74195.1 - 3.6e-05 23.6 0.0 7.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KNZ74195.1 - 0.00025 20.0 0.0 0.0003 19.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KNZ74195.1 - 0.00029 20.4 0.1 0.00079 19.0 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 KNZ74195.1 - 0.00038 19.6 0.1 0.0008 18.5 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KNZ74195.1 - 0.0012 17.4 0.1 0.0017 16.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein XdhC_C PF13478.1 KNZ74195.1 - 0.0018 18.6 0.1 0.059 13.6 0.0 2.8 3 0 0 3 3 3 1 XdhC Rossmann domain SE PF08491.5 KNZ74195.1 - 0.012 14.5 0.0 0.17 10.7 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_2 PF00890.19 KNZ74195.1 - 0.012 14.4 0.1 0.018 13.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 KNZ74195.1 - 0.015 14.9 0.1 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KNZ74195.1 - 0.022 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.16 KNZ74195.1 - 0.035 13.9 0.2 0.078 12.8 0.1 1.6 1 0 0 1 1 1 0 ThiF family Trp_halogenase PF04820.9 KNZ74195.1 - 0.066 11.8 0.7 0.63 8.5 0.1 2.2 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.7 KNZ74195.1 - 0.11 11.3 0.1 0.22 10.3 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein AT_hook PF02178.14 KNZ74196.1 - 4.5e-06 25.7 50.5 0.021 14.4 2.6 4.5 4 0 0 4 4 4 4 AT hook motif PRKCSH PF07915.8 KNZ74197.1 - 1.9e-16 60.5 0.4 3.6e-16 59.7 0.3 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 KNZ74197.1 - 0.0013 18.1 0.0 0.0064 15.9 0.0 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Pkinase PF00069.20 KNZ74198.1 - 1.3e-52 178.5 0.0 1.3e-51 175.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain DEAD PF00270.24 KNZ74198.1 - 1.8e-41 141.4 0.0 1.7e-40 138.2 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ74198.1 - 4.5e-24 84.1 0.0 9.7e-24 83.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase_Tyr PF07714.12 KNZ74198.1 - 7.8e-24 84.1 0.0 1.5e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SNF2_N PF00176.18 KNZ74198.1 - 3.8e-05 22.6 0.0 6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KNZ74198.1 - 0.022 14.6 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Kinase-like PF14531.1 KNZ74198.1 - 0.11 11.4 0.0 0.57 9.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like EF_assoc_2 PF08356.7 KNZ74199.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 EF hand associated RhoGEF PF00621.15 KNZ74200.1 - 9.9e-17 61.3 0.0 1.5e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Asn_synthase PF00733.16 KNZ74201.1 - 4e-70 236.2 0.0 5.9e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KNZ74201.1 - 1.7e-34 118.2 0.0 3e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KNZ74201.1 - 6.1e-28 97.4 0.0 1.4e-27 96.2 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KNZ74201.1 - 1.3e-06 27.7 0.0 4.8e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Aluminium induced protein GATase_2 PF00310.16 KNZ74201.1 - 0.00045 19.0 0.0 1.6 7.3 0.0 3.0 1 1 2 3 3 3 2 Glutamine amidotransferases class-II QueC PF06508.8 KNZ74201.1 - 0.019 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 KNZ74201.1 - 0.07 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD synthase Syntaxin PF00804.20 KNZ74202.1 - 6.6e-10 39.0 3.1 6.6e-10 39.0 2.2 2.8 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.14 KNZ74202.1 - 1.1e-06 28.1 3.2 1.1e-06 28.1 2.2 3.0 2 1 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 KNZ74202.1 - 0.00038 20.4 3.4 0.00038 20.4 2.4 2.1 2 0 0 2 2 2 1 Syntaxin-like protein Tweety PF04906.8 KNZ74202.1 - 0.093 11.1 2.0 0.44 8.8 0.0 2.2 2 1 0 2 2 2 0 Tweety DUF2116 PF09889.4 KNZ74202.1 - 0.16 11.8 0.2 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DASH_Dam1 PF08653.5 KNZ74202.1 - 2.8 7.7 5.5 2.4 7.9 0.2 2.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF4055 PF13264.1 KNZ74202.1 - 3.8 7.5 7.4 0.63 10.1 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) TBPIP PF07106.8 KNZ74202.1 - 3.9 7.0 8.1 2.1 7.8 0.3 2.6 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CDP-OH_P_transf PF01066.16 KNZ74203.1 - 3.9e-20 72.0 4.0 3.9e-20 72.0 2.8 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase AAA PF00004.24 KNZ74204.1 - 7.3e-36 123.2 0.0 1.9e-35 121.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KNZ74204.1 - 2.9e-05 24.8 0.2 0.00039 21.2 0.0 2.9 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KNZ74204.1 - 8.9e-05 22.5 6.4 0.0026 17.7 0.1 4.2 3 1 2 5 5 5 1 AAA ATPase domain AAA_22 PF13401.1 KNZ74204.1 - 0.0004 20.5 0.1 0.019 15.0 0.0 3.0 2 1 1 3 3 2 1 AAA domain AAA_5 PF07728.9 KNZ74204.1 - 0.00062 19.4 0.1 0.0045 16.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KNZ74204.1 - 0.0011 18.6 0.1 0.0052 16.4 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KNZ74204.1 - 0.0014 18.2 0.0 0.0038 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KNZ74204.1 - 0.002 17.9 0.0 0.0097 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KNZ74204.1 - 0.009 15.4 0.1 0.062 12.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.7 KNZ74204.1 - 0.013 14.5 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KNZ74204.1 - 0.017 15.0 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KNZ74204.1 - 0.022 15.0 0.6 0.12 12.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KNZ74204.1 - 0.029 14.2 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain IPT PF01745.11 KNZ74204.1 - 0.066 12.3 0.1 4.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 KNZ74204.1 - 0.07 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 KNZ74204.1 - 0.098 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus UCH PF00443.24 KNZ74204.1 - 0.11 11.5 0.1 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase AAA_10 PF12846.2 KNZ74204.1 - 0.16 11.4 0.3 22 4.3 0.0 2.8 2 1 1 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 KNZ74204.1 - 0.18 11.9 0.0 0.46 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.10 KNZ74204.1 - 0.27 9.8 0.0 0.44 9.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SMC_Nse1 PF07574.8 KNZ74205.1 - 9.7e-32 110.2 0.2 1.9e-30 106.0 0.1 2.2 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex HTH_27 PF13463.1 KNZ74205.1 - 0.026 14.8 0.0 0.097 13.0 0.0 1.9 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_13 PF11972.3 KNZ74205.1 - 0.13 12.0 0.0 0.44 10.4 0.0 1.8 1 0 0 1 1 1 0 HTH DNA binding domain PBP1_TM PF14812.1 KNZ74205.1 - 1.3 9.4 5.4 2.3 8.5 3.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDP-OH_P_transf PF01066.16 KNZ74206.1 - 3.3e-11 43.3 4.6 6.9e-11 42.3 3.2 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase USP7_ICP0_bdg PF12436.3 KNZ74208.1 - 6.6e-82 274.4 0.2 1.5e-81 273.3 0.1 1.6 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KNZ74208.1 - 1.5e-64 217.3 8.9 3.8e-63 212.7 0.3 3.1 4 0 0 4 4 4 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 KNZ74208.1 - 6.6e-58 195.9 0.4 1.2e-57 195.0 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNZ74208.1 - 8.1e-33 114.1 0.0 1.4e-32 113.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KNZ74208.1 - 2e-07 31.2 0.7 5e-06 26.7 0.0 3.1 3 0 0 3 3 3 1 MATH domain UN_NPL4 PF11543.3 KNZ74208.1 - 0.042 14.1 0.0 0.39 11.0 0.0 2.7 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 Sec66 PF09802.4 KNZ74209.1 - 4e-48 163.3 0.0 4.7e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 StbA PF06406.6 KNZ74209.1 - 0.045 12.6 0.1 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 StbA protein Citrate_synt PF00285.16 KNZ74210.1 - 8e-102 340.5 0.0 9.3e-102 340.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase XH PF03469.9 KNZ74210.1 - 0.065 12.9 1.2 0.099 12.2 0.2 1.7 2 0 0 2 2 2 0 XH domain SNAPc19 PF15497.1 KNZ74210.1 - 0.1 12.7 0.5 0.2 11.9 0.4 1.4 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 B56 PF01603.15 KNZ74212.1 - 4.7e-168 559.0 5.1 5.6e-168 558.7 3.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) HSP70 PF00012.15 KNZ74213.1 - 5.5e-242 804.0 6.1 9.2e-163 542.3 0.1 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 KNZ74213.1 - 2.3e-12 46.1 0.0 3.5e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 KNZ74213.1 - 0.0067 15.5 0.1 0.018 14.1 0.1 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase GRP PF07172.6 KNZ74213.1 - 0.041 14.3 4.1 0.11 12.9 2.9 1.6 1 0 0 1 1 1 0 Glycine rich protein family StbA PF06406.6 KNZ74213.1 - 0.066 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 StbA protein AAA_23 PF13476.1 KNZ74213.1 - 1.8 8.8 7.7 0.53 10.5 2.3 2.1 2 1 0 2 2 2 0 AAA domain PhoD PF09423.5 KNZ74214.1 - 4.5e-101 338.6 0.4 5e-60 203.3 0.2 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase Fungal_trans PF04082.13 KNZ74215.1 - 8.8e-18 64.1 0.9 1.7e-17 63.1 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DivIC PF04977.10 KNZ74216.1 - 0.0018 17.7 4.0 0.0024 17.2 2.7 1.2 1 0 0 1 1 1 1 Septum formation initiator HALZ PF02183.13 KNZ74216.1 - 0.0028 17.3 1.0 0.0048 16.5 0.7 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper CENP-Q PF13094.1 KNZ74216.1 - 0.017 15.1 1.8 0.017 15.1 1.2 1.0 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4164 PF13747.1 KNZ74216.1 - 0.018 15.1 3.1 0.019 15.0 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) bZIP_Maf PF03131.12 KNZ74216.1 - 0.022 15.0 5.6 0.025 14.8 3.9 1.1 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4140 PF13600.1 KNZ74216.1 - 0.024 15.0 1.3 0.029 14.8 0.9 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF2937 PF11157.3 KNZ74216.1 - 0.031 13.5 1.4 0.035 13.4 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF972 PF06156.8 KNZ74216.1 - 0.032 14.5 1.5 0.037 14.3 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF1640 PF07798.6 KNZ74216.1 - 0.051 13.6 2.0 0.055 13.5 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) GAS PF13851.1 KNZ74216.1 - 0.052 12.7 3.2 0.059 12.5 2.2 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding XRCC4 PF06632.7 KNZ74216.1 - 0.06 12.1 1.1 0.067 12.0 0.8 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Imm16 PF15565.1 KNZ74216.1 - 0.06 13.2 0.0 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 16 DUF904 PF06005.7 KNZ74216.1 - 0.077 13.2 2.5 0.11 12.8 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF2163 PF09931.4 KNZ74216.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) DUF16 PF01519.11 KNZ74216.1 - 0.11 12.7 0.7 0.13 12.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 Cluap1 PF10234.4 KNZ74216.1 - 0.11 11.6 3.2 0.13 11.4 2.2 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.11 KNZ74216.1 - 0.13 10.4 0.7 0.14 10.3 0.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like Atg14 PF10186.4 KNZ74216.1 - 0.13 11.2 3.2 0.15 10.9 2.2 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3782 PF12644.2 KNZ74216.1 - 0.13 12.0 1.4 0.16 11.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Glyco_transf_92 PF01697.22 KNZ74216.1 - 0.14 11.4 0.1 0.15 11.3 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 92 Mnd1 PF03962.10 KNZ74216.1 - 0.15 11.7 3.6 0.19 11.4 2.5 1.1 1 0 0 1 1 1 0 Mnd1 family V_ATPase_I PF01496.14 KNZ74216.1 - 0.16 9.8 1.6 0.17 9.6 1.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Matrilin_ccoil PF10393.4 KNZ74216.1 - 0.23 10.8 1.6 0.33 10.3 1.1 1.4 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin HNOBA PF07701.9 KNZ74216.1 - 0.26 10.4 1.9 0.27 10.4 1.3 1.1 1 0 0 1 1 1 0 Heme NO binding associated APG6 PF04111.7 KNZ74216.1 - 0.44 9.5 3.1 0.49 9.3 2.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2681 PF10883.3 KNZ74216.1 - 0.45 10.7 3.7 0.63 10.2 2.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) DUF3886 PF13025.1 KNZ74216.1 - 1.3 9.0 8.1 1.8 8.6 5.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3886) GrpE PF01025.14 KNZ74216.1 - 2.9 7.4 7.0 5.4 6.5 4.9 1.3 1 1 0 1 1 1 0 GrpE ox_reductase_C PF08635.5 KNZ74217.1 - 2.6e-72 240.8 0.4 4.2e-72 240.1 0.3 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 KNZ74217.1 - 8.8e-24 84.3 0.1 2.4e-23 82.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KNZ74217.1 - 0.0022 17.7 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DcpS_C PF11969.3 KNZ74218.1 - 9.8e-08 32.2 0.3 4.6e-07 30.0 0.1 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KNZ74218.1 - 4.5e-05 23.9 0.0 0.00015 22.1 0.0 1.9 1 0 0 1 1 1 1 HIT domain zf-C2H2_2 PF12756.2 KNZ74218.1 - 0.035 14.1 1.0 0.083 13.0 0.7 1.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) ROS_MUCR PF05443.6 KNZ74218.1 - 0.064 13.0 0.1 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 ROS/MUCR transcriptional regulator protein 2OG-FeII_Oxy_2 PF13532.1 KNZ74219.1 - 5.6e-36 124.1 0.0 7.6e-34 117.2 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily RabGAP-TBC PF00566.13 KNZ74219.1 - 7.6e-36 123.5 10.6 5.1e-34 117.6 7.3 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain SHR3_chaperone PF08229.6 KNZ74219.1 - 1e-17 63.7 0.6 1.7e-17 63.0 0.4 1.3 1 0 0 1 1 1 1 ER membrane protein SH3 DUF3548 PF12068.3 KNZ74219.1 - 4.4e-07 29.4 4.5 0.0009 18.5 0.0 4.1 4 1 0 4 4 4 2 Domain of unknown function (DUF3548) LETM1 PF07766.8 KNZ74220.1 - 2.1e-83 279.4 2.8 3.3e-81 272.2 0.2 3.2 2 2 2 4 4 4 2 LETM1-like protein EF-hand_1 PF00036.27 KNZ74220.1 - 0.00025 20.1 0.0 0.2 11.0 0.0 3.7 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 KNZ74220.1 - 0.00033 20.7 0.0 0.03 14.4 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KNZ74220.1 - 0.00053 19.6 0.0 15 5.8 0.0 4.2 3 0 0 3 3 3 1 EF-hand domain SAP PF02037.22 KNZ74220.1 - 0.0016 17.8 3.4 0.0035 16.7 0.0 3.3 4 0 0 4 4 4 1 SAP domain EF-hand_8 PF13833.1 KNZ74220.1 - 0.0037 16.8 0.1 0.031 13.8 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KNZ74220.1 - 0.02 14.1 0.0 0.82 9.1 0.0 3.0 2 0 0 2 2 2 0 EF hand DUF3719 PF12516.3 KNZ74220.1 - 0.11 12.1 1.1 0.19 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) Oligomerisation PF02410.10 KNZ74221.1 - 7.7e-06 25.8 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Oligomerisation domain G-patch PF01585.18 KNZ74222.1 - 2.9e-07 30.1 2.1 2.9e-07 30.1 1.5 2.0 2 0 0 2 2 2 1 G-patch domain SAGA-Tad1 PF12767.2 KNZ74222.1 - 0.93 9.1 3.3 35 3.9 0.0 3.2 2 1 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit FAD_binding_2 PF00890.19 KNZ74223.1 - 1.4e-121 406.3 1.1 1.7e-121 405.9 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KNZ74223.1 - 2.1e-45 153.6 0.2 3.2e-45 153.1 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 KNZ74223.1 - 1.2e-06 28.6 0.0 0.00038 20.3 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KNZ74223.1 - 1.4e-06 27.5 0.3 0.0014 17.7 0.0 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KNZ74223.1 - 6.9e-06 25.1 1.2 0.0061 15.4 1.6 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 KNZ74223.1 - 0.00017 20.6 1.5 0.0007 18.5 1.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KNZ74223.1 - 0.0034 16.4 0.2 0.0057 15.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KNZ74223.1 - 0.12 10.8 2.3 0.25 9.7 0.6 2.2 3 0 0 3 3 3 0 HI0933-like protein RabGAP-TBC PF00566.13 KNZ74224.1 - 3.7e-34 118.0 0.0 1.5e-16 60.5 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain TBCC PF07986.7 KNZ74224.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C CLTH PF10607.4 KNZ74225.1 - 1.1e-21 77.0 0.0 1.9e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KNZ74225.1 - 3.3e-18 65.1 2.8 6.6e-18 64.1 0.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.7 KNZ74225.1 - 0.0015 17.8 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.1 KNZ74225.1 - 0.017 14.8 0.2 0.027 14.1 0.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 KNZ74225.1 - 0.019 14.7 0.3 0.032 14.0 0.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 KNZ74225.1 - 0.12 12.0 0.3 0.2 11.3 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KNZ74225.1 - 0.16 11.5 1.2 0.32 10.5 0.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit WD40 PF00400.27 KNZ74226.1 - 0.0017 18.1 0.6 0.028 14.3 0.0 3.1 3 1 0 3 3 3 1 WD domain, G-beta repeat PQQ PF01011.16 KNZ74226.1 - 0.12 11.9 0.3 4 7.1 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat Pirin PF02678.11 KNZ74227.1 - 3.6e-29 100.7 0.8 3.6e-29 100.7 0.5 1.5 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 KNZ74227.1 - 2.9e-17 62.6 0.0 1.7e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KNZ74227.1 - 0.097 12.1 1.0 0.19 11.2 0.7 1.5 1 0 0 1 1 1 0 Cupin domain AA_permease PF00324.16 KNZ74228.1 - 1.8e-117 392.6 42.1 2.2e-117 392.3 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KNZ74228.1 - 8.1e-30 103.6 47.8 1e-29 103.3 33.1 1.1 1 0 0 1 1 1 1 Amino acid permease ECH PF00378.15 KNZ74229.1 - 8.2e-28 97.1 0.0 9.2e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_M17_N PF02789.12 KNZ74229.1 - 0.073 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain OTU PF02338.14 KNZ74231.1 - 8e-18 65.1 0.0 1.5e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KNZ74231.1 - 3.9e-06 26.4 0.0 0.08 12.2 0.0 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain NCKAP5 PF15246.1 KNZ74231.1 - 0.0047 16.3 5.0 0.0062 15.9 3.5 1.1 1 0 0 1 1 1 1 Nck-associated protein 5, Peripheral clock protein Metal_resist PF13801.1 KNZ74231.1 - 0.18 11.7 13.3 0.43 10.5 9.3 1.7 1 1 0 1 1 1 0 Heavy-metal resistance Adaptin_N PF01602.15 KNZ74232.1 - 6.5e-133 443.8 0.8 8.1e-133 443.5 0.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KNZ74232.1 - 1.3e-24 87.0 0.0 9.2e-23 80.9 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KNZ74232.1 - 9.8e-17 61.0 12.6 6e-09 36.0 0.1 5.6 4 1 2 6 6 6 4 HEAT repeats Arm PF00514.18 KNZ74232.1 - 7.5e-08 31.9 1.5 0.27 11.1 0.0 5.5 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KNZ74232.1 - 9.1e-08 31.5 9.5 0.0025 17.7 0.0 6.8 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 KNZ74232.1 - 1.5e-05 25.3 6.1 0.54 10.8 0.0 6.7 5 2 2 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 KNZ74232.1 - 0.0027 17.1 0.1 0.066 12.5 0.0 2.7 2 1 0 2 2 2 1 CLASP N terminal DUF4477 PF14780.1 KNZ74233.1 - 2.5e-06 27.0 2.5 0.00028 20.3 1.7 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4477) DUF4282 PF14110.1 KNZ74233.1 - 0.029 14.5 0.7 0.053 13.7 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) Cu_bind_like PF02298.12 KNZ74234.1 - 0.00031 20.4 0.2 0.00071 19.3 0.2 1.6 1 0 0 1 1 1 1 Plastocyanin-like domain KRTAP PF11759.3 KNZ74234.1 - 3.6 7.8 15.8 2.9 8.2 9.5 1.9 1 1 0 1 1 1 0 Keratin-associated matrix Pyr_redox_2 PF07992.9 KNZ74235.1 - 5.1e-07 29.7 0.0 1.4e-05 25.0 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNZ74235.1 - 0.0058 16.4 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding UEV PF05743.8 KNZ74236.1 - 3.8e-37 126.6 0.0 5.8e-37 126.0 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 KNZ74236.1 - 4.4e-27 93.4 0.6 4.4e-27 93.4 0.4 2.0 2 0 0 2 2 2 1 Vps23 core domain TEA PF01285.13 KNZ74237.1 - 3.8e-09 36.2 0.1 3.8e-09 36.2 0.1 1.5 2 0 0 2 2 2 1 TEA/ATTS domain family NOC3p PF07540.6 KNZ74238.1 - 2.7e-28 98.0 0.0 1.6e-27 95.5 0.0 2.5 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.12 KNZ74238.1 - 3.3e-21 75.4 0.1 2.6e-19 69.2 0.0 3.0 2 1 1 3 3 3 1 CBF/Mak21 family DUF1843 PF08898.5 KNZ74238.1 - 0.79 9.8 3.2 2.1 8.4 2.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Apc5 PF12862.2 KNZ74239.1 - 6.2e-10 38.7 0.1 3.3e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 KNZ74239.1 - 0.27 11.1 5.9 24 4.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat CLASP_N PF12348.3 KNZ74240.1 - 9.4e-27 93.8 1.4 5.2e-08 32.5 0.0 5.7 5 0 0 5 5 5 4 CLASP N terminal HEAT PF02985.17 KNZ74240.1 - 2.4e-14 52.0 14.3 1.8 8.8 0.0 12.8 12 0 0 12 12 12 2 HEAT repeat HEAT_2 PF13646.1 KNZ74240.1 - 7.9e-10 38.8 23.2 0.075 13.3 0.9 10.0 9 3 1 11 11 11 3 HEAT repeats HEAT_EZ PF13513.1 KNZ74240.1 - 5.1e-05 23.6 21.4 3.4 8.2 0.1 8.5 9 0 0 9 9 7 4 HEAT-like repeat TAN PF11640.3 KNZ74240.1 - 0.00013 21.6 4.8 0.12 12.1 0.0 5.8 8 0 0 8 8 8 1 Telomere-length maintenance and DNA damage repair Cnd1 PF12717.2 KNZ74240.1 - 0.004 17.0 0.0 9.5 6.0 0.0 5.6 6 1 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KNZ74240.1 - 0.011 16.1 0.0 25 5.3 0.0 5.9 7 1 0 7 7 7 0 Vacuolar 14 Fab1-binding region TIP120 PF08623.5 KNZ74240.1 - 0.028 14.0 0.0 0.17 11.4 0.0 2.4 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Arm PF00514.18 KNZ74240.1 - 0.039 13.7 0.2 39 4.2 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 KNZ74240.1 - 0.092 12.6 0.1 27 4.7 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) ParcG PF10274.4 KNZ74240.1 - 0.26 11.1 1.7 58 3.5 0.0 4.6 5 0 0 5 5 5 0 Parkin co-regulated protein Acyltransferase PF01553.16 KNZ74241.1 - 2.1e-11 43.4 0.0 4.1e-10 39.2 0.0 2.5 2 1 0 2 2 2 1 Acyltransferase DUF2484 PF10658.4 KNZ74241.1 - 2.4 8.3 7.6 16 5.6 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) Peptidase_M24 PF00557.19 KNZ74242.1 - 1.4e-33 116.2 0.1 3.2e-26 92.1 0.0 2.1 1 1 1 2 2 2 2 Metallopeptidase family M24 IF-2B PF01008.12 KNZ74244.1 - 5.5e-56 189.6 0.0 7.3e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family PGBA_N PF15436.1 KNZ74244.1 - 0.02 14.1 0.0 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA N-terminal Cyclin_N PF00134.18 KNZ74245.1 - 1.9e-10 40.4 0.0 9.3e-10 38.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KNZ74245.1 - 9.5e-08 31.9 1.8 0.0078 16.1 0.1 2.6 1 1 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 KNZ74245.1 - 0.00015 21.4 0.3 0.0022 17.7 0.0 2.6 3 0 0 3 3 3 1 Transcription factor TFIIB repeat TSA PF03249.8 KNZ74246.1 - 0.17 10.3 0.1 0.18 10.3 0.1 1.1 1 0 0 1 1 1 0 Type specific antigen Vanabin-2 PF11437.3 KNZ74247.1 - 0.39 10.7 3.3 0.52 10.3 2.3 1.2 1 0 0 1 1 1 0 Vanadium-binding protein 2 Ribosomal_S21 PF01165.15 KNZ74248.1 - 4.5e-14 51.6 3.2 8e-14 50.8 2.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 ADIP PF11559.3 KNZ74248.1 - 0.043 13.7 3.9 0.057 13.3 2.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding RWD PF05773.17 KNZ74249.1 - 1.4e-14 53.9 0.0 2.9e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 RWD domain Abhydrolase_6 PF12697.2 KNZ74250.1 - 1.1e-10 41.8 0.9 1.6e-10 41.3 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ74250.1 - 0.0001 21.9 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 KNZ74250.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Cutinase CSTF2_hinge PF14327.1 KNZ74251.1 - 0.0094 16.0 0.7 0.024 14.6 0.5 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 DUF748 PF05359.6 KNZ74252.1 - 0.016 15.2 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) adh_short PF00106.20 KNZ74253.1 - 1.9e-25 89.7 7.4 1.2e-23 83.8 0.4 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KNZ74253.1 - 4.6e-09 36.1 2.8 3.5e-08 33.3 0.1 2.1 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KNZ74253.1 - 0.083 12.6 0.8 0.21 11.4 0.6 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SET PF00856.23 KNZ74254.1 - 8e-07 29.5 0.0 2.2e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 SET domain DUF3398 PF11878.3 KNZ74254.1 - 0.087 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) DUF4116 PF13475.1 KNZ74254.1 - 0.16 11.5 0.1 0.73 9.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) SUI1 PF01253.17 KNZ74255.1 - 1.2e-20 73.0 2.4 1.6e-20 72.7 0.9 1.8 1 1 1 2 2 2 1 Translation initiation factor SUI1 DUF3584 PF12128.3 KNZ74255.1 - 0.003 14.9 0.9 0.0034 14.8 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TnpV PF14198.1 KNZ74255.1 - 0.018 14.9 1.4 0.032 14.1 1.0 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Ribosomal_L18_c PF14204.1 KNZ74255.1 - 0.07 13.7 3.1 0.13 12.7 2.1 1.4 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region Fib_alpha PF08702.5 KNZ74255.1 - 0.075 13.1 1.1 0.11 12.5 0.7 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spore_III_AF PF09581.5 KNZ74255.1 - 2.7 7.8 7.9 4.8 6.9 5.5 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) PAP2 PF01569.16 KNZ74257.1 - 4.7e-16 58.6 10.1 6.7e-16 58.1 7.0 1.1 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 KNZ74257.1 - 0.00091 18.9 0.3 0.00091 18.9 0.2 2.1 2 1 0 2 2 2 1 Divergent PAP2 family DUF1469 PF07332.6 KNZ74257.1 - 0.028 14.1 5.4 0.82 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF1211 PF06736.6 KNZ74257.1 - 0.65 10.1 7.8 1.1 9.4 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1211) DUF4191 PF13829.1 KNZ74257.1 - 2.8 7.0 8.8 0.38 9.8 3.2 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4191) UbiA PF01040.13 KNZ74257.1 - 9.1 5.4 13.3 4.5 6.4 5.7 2.1 1 1 1 2 2 2 0 UbiA prenyltransferase family DnaJ PF00226.26 KNZ74258.1 - 3.1e-20 71.6 1.5 1.4e-19 69.5 0.3 2.5 2 0 0 2 2 2 1 DnaJ domain RAI16-like PF10257.4 KNZ74259.1 - 3.1e-76 256.6 0.1 4.1e-76 256.1 0.1 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein CPSF_A PF03178.10 KNZ74260.1 - 4.1e-74 249.5 0.0 7.6e-74 248.6 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region ABC_membrane_3 PF13748.1 KNZ74260.1 - 0.12 11.4 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region DEAD PF00270.24 KNZ74262.1 - 5.5e-17 61.7 0.0 1.8e-16 60.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ74262.1 - 5.9e-07 29.2 0.1 1.7e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ74262.1 - 0.013 15.3 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF870 PF05912.6 KNZ74262.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF870) ATP_bind_1 PF03029.12 KNZ74263.1 - 1.1e-75 254.2 0.0 1.3e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 KNZ74263.1 - 0.084 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KNZ74263.1 - 0.14 12.1 0.0 1.8 8.5 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase ArgK PF03308.11 KNZ74263.1 - 0.14 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 KNZ74263.1 - 3.4 8.5 6.5 0.54 11.0 0.4 2.5 3 1 0 3 3 3 0 AAA domain APH PF01636.18 KNZ74264.1 - 1.5e-10 41.2 0.0 3.7e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KNZ74264.1 - 1.6e-05 23.7 0.0 0.0044 15.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) GMC_oxred_N PF00732.14 KNZ74265.1 - 1.7e-65 221.0 0.0 2.2e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ74265.1 - 1.5e-34 119.3 0.0 2.4e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KNZ74265.1 - 0.0009 19.2 0.0 0.0045 16.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KNZ74265.1 - 0.0023 16.8 0.1 0.057 12.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KNZ74265.1 - 0.0034 16.3 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KNZ74265.1 - 0.029 13.2 0.0 0.083 11.7 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 KNZ74266.1 - 1.9e-65 220.9 0.0 2.4e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ74266.1 - 4.3e-38 130.8 0.0 6.9e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KNZ74266.1 - 7.4e-05 22.6 0.0 0.00023 21.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KNZ74266.1 - 0.00016 20.7 0.1 0.00025 20.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KNZ74266.1 - 0.003 16.4 0.0 0.0092 14.8 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KNZ74266.1 - 0.0039 16.1 0.0 0.0067 15.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.13 KNZ74266.1 - 0.018 15.0 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 KNZ74266.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KNZ74266.1 - 0.09 11.3 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 KNZ74266.1 - 0.11 11.5 0.1 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family TPR_12 PF13424.1 KNZ74267.1 - 5.4e-13 48.6 12.1 1.1e-05 25.2 0.8 4.5 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ74267.1 - 1.6e-08 33.7 10.5 0.0038 17.0 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ74267.1 - 3.8e-08 32.5 1.7 0.0066 16.1 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ74267.1 - 3.4e-06 26.6 11.3 0.086 12.5 0.1 4.3 3 1 1 4 4 4 3 TPR repeat TPR_14 PF13428.1 KNZ74267.1 - 0.00024 21.4 11.0 0.25 12.0 0.1 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ74267.1 - 0.00028 20.4 6.6 4.8 7.2 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ74267.1 - 0.0006 19.3 8.0 0.067 12.8 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ74267.1 - 0.007 17.0 12.4 0.015 15.9 0.1 4.3 3 1 1 5 5 5 1 Tetratricopeptide repeat Foie-gras_1 PF11817.3 KNZ74267.1 - 0.016 14.7 4.9 0.1 12.0 0.3 2.3 2 0 0 2 2 2 0 Foie gras liver health family 1 TPR_10 PF13374.1 KNZ74267.1 - 0.044 13.7 6.7 2.9 7.9 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ74267.1 - 0.056 13.9 3.7 0.41 11.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ74267.1 - 0.059 13.7 8.7 2.8 8.3 0.1 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KNZ74267.1 - 0.11 13.0 0.5 4.3 8.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SNAP PF14938.1 KNZ74267.1 - 0.15 11.2 2.1 1.6 7.8 0.2 2.4 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP WD40 PF00400.27 KNZ74269.1 - 7.3e-17 60.5 10.1 0.00057 19.6 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat SRA1 PF07304.6 KNZ74269.1 - 3.8e-08 33.2 0.0 3.8e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 KNZ74269.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 DUF3106 PF11304.3 KNZ74271.1 - 0.035 14.5 0.1 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) rve PF00665.21 KNZ74272.1 - 0.029 14.4 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain ELFV_dehydrog PF00208.16 KNZ74273.1 - 6.5e-72 242.0 0.2 8.1e-72 241.7 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KNZ74273.1 - 1.7e-41 140.8 0.0 4.6e-36 123.2 0.0 2.5 2 0 0 2 2 2 2 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Transp_cyt_pur PF02133.10 KNZ74275.1 - 3.4e-27 95.0 33.6 2.5e-26 92.2 23.3 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Acetyltransf_3 PF13302.1 KNZ74276.1 - 5.6e-13 49.2 0.0 7.9e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ74276.1 - 0.00022 21.1 0.0 0.00089 19.2 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KNZ74276.1 - 0.14 12.0 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-RING_2 PF13639.1 KNZ74277.1 - 2e-07 30.7 7.4 4.9e-07 29.4 5.1 1.8 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 KNZ74277.1 - 9.5e-06 25.4 3.9 2.1e-05 24.3 2.7 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 KNZ74277.1 - 1.3e-05 25.1 3.6 3.3e-05 23.8 2.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KNZ74277.1 - 0.0015 18.3 1.5 0.0035 17.1 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KNZ74277.1 - 0.03 14.3 6.0 0.096 12.7 4.2 2.0 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 KNZ74277.1 - 0.19 11.5 3.6 0.12 12.1 1.0 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 KNZ74277.1 - 0.22 11.2 7.5 0.57 9.8 5.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ74277.1 - 2.6 8.1 8.6 8 6.5 6.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KNZ74277.1 - 4.1 7.4 6.1 9.9 6.2 4.3 1.7 1 0 0 1 1 1 0 RING-like domain Glyco_transf_90 PF05686.7 KNZ74278.1 - 4e-14 52.1 0.6 5.1e-13 48.4 0.1 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 Flavin_Reduct PF01613.13 KNZ74279.1 - 9.5e-23 80.7 0.0 1.3e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain LAT PF15234.1 KNZ74279.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.4 2 0 0 2 2 2 0 Linker for activation of T-cells Peptidase_M43 PF05572.8 KNZ74280.1 - 2.9e-19 69.1 0.0 4.4e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 KNZ74280.1 - 1.7e-06 28.5 0.0 3.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KNZ74280.1 - 4.2e-06 26.9 0.1 5.7e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KNZ74280.1 - 0.00026 20.9 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KNZ74280.1 - 0.003 17.1 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 KNZ74280.1 - 0.021 14.1 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 KNZ74280.1 - 0.095 12.4 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin Methyltransf_2 PF00891.13 KNZ74282.1 - 1.7e-30 106.0 0.0 2.3e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KNZ74282.1 - 0.00048 20.6 0.0 0.00087 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ74282.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ74282.1 - 0.0012 19.2 0.0 0.0068 16.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.7 KNZ74282.1 - 0.032 13.7 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_PK PF05891.7 KNZ74282.1 - 0.074 12.3 0.0 0.21 10.8 0.0 1.8 2 1 0 2 2 2 0 AdoMet dependent proline di-methyltransferase WD40 PF00400.27 KNZ74283.1 - 2.4e-36 122.2 22.2 9.1e-09 34.8 0.3 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CytB6-F_Fe-S PF08802.5 KNZ74288.1 - 0.014 15.3 0.5 3.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit PIF1 PF05970.9 KNZ74291.1 - 6.7e-08 31.8 0.1 1.6e-07 30.5 0.1 1.5 1 1 0 1 1 1 1 PIF1-like helicase Chitin_synth_1N PF08407.6 KNZ74291.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Chitin synthase N-terminal APH PF01636.18 KNZ74292.1 - 3.1e-07 30.3 0.1 6.8e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ74292.1 - 0.0008 18.6 0.0 0.00099 18.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 KNZ74292.1 - 0.0013 18.3 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Sugar_tr PF00083.19 KNZ74293.1 - 6.8e-38 130.4 23.8 9.9e-38 129.8 16.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ74293.1 - 7.9e-36 123.4 28.7 7.9e-36 123.4 19.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KNZ74293.1 - 0.018 14.7 6.2 1.5 8.6 0.0 3.1 3 0 0 3 3 3 0 MFS_1 like family MtrF PF09472.5 KNZ74293.1 - 2.6 7.3 5.5 3.2 7.0 1.2 2.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) APH PF01636.18 KNZ74295.1 - 1.9e-05 24.5 0.0 3.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ74295.1 - 0.00048 19.7 1.0 0.0092 15.5 0.0 2.6 3 0 0 3 3 3 1 Choline/ethanolamine kinase DUF4135 PF13575.1 KNZ74295.1 - 0.12 11.3 0.2 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Pkinase PF00069.20 KNZ74295.1 - 0.15 11.2 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Laminin_II PF06009.7 KNZ74297.1 - 0.085 12.6 2.6 0.13 12.0 0.3 2.1 2 0 0 2 2 2 0 Laminin Domain II Racemase_4 PF13615.1 KNZ74297.1 - 1.7 8.9 5.6 16 5.8 0.4 2.3 2 0 0 2 2 2 0 Putative alanine racemase CRISPR_assoc PF08798.6 KNZ74298.1 - 0.0062 16.3 0.0 0.0073 16.0 0.0 1.1 1 0 0 1 1 1 1 CRISPR associated protein zf-CSL PF05207.8 KNZ74298.1 - 0.057 12.9 0.1 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 CSL zinc finger Suf PF05843.9 KNZ74299.1 - 0.012 15.3 0.7 0.012 15.3 0.5 1.5 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) Pkinase PF00069.20 KNZ74300.1 - 1.2e-13 50.8 0.0 6.4e-13 48.4 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74300.1 - 0.0011 18.0 0.0 0.046 12.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase PIF1 PF05970.9 KNZ74301.1 - 9.4e-13 47.8 0.0 1.3e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase MFS_1 PF07690.11 KNZ74302.1 - 1.4e-34 119.3 34.3 1.4e-34 119.3 23.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_1 PF01979.15 KNZ74303.1 - 1.2e-14 54.7 0.0 4.9e-14 52.7 0.0 1.9 2 1 1 3 3 3 1 Amidohydrolase family Amidohydro_5 PF13594.1 KNZ74303.1 - 4e-08 32.9 0.0 1.4e-07 31.2 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KNZ74303.1 - 8e-06 26.0 0.0 4.3e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KNZ74303.1 - 1.2e-05 24.7 0.1 0.14 11.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family HHH_5 PF14520.1 KNZ74303.1 - 0.098 12.8 0.1 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain Cutinase PF01083.17 KNZ74304.1 - 3.6e-45 153.8 0.3 4.3e-45 153.6 0.2 1.0 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 KNZ74304.1 - 4.4e-05 23.1 0.0 6.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 KNZ74304.1 - 0.00043 19.7 0.1 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 KNZ74304.1 - 0.00043 20.2 0.2 0.00049 20.0 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 KNZ74304.1 - 0.00061 19.2 0.1 0.00076 18.9 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 KNZ74304.1 - 0.0016 18.0 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold VirJ PF06057.6 KNZ74304.1 - 0.0016 18.2 0.0 0.0022 17.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 KNZ74304.1 - 0.0041 16.8 0.1 0.0047 16.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KNZ74304.1 - 0.017 15.3 0.0 0.022 15.0 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain LIP PF03583.9 KNZ74304.1 - 0.033 13.3 0.3 0.046 12.9 0.2 1.2 1 0 0 1 1 1 0 Secretory lipase zf-Paramyx-P PF13008.2 KNZ74306.1 - 0.075 12.2 1.9 0.91 8.7 0.2 2.3 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein F-box-like PF12937.2 KNZ74307.1 - 9.8e-05 22.0 1.4 0.0094 15.6 0.0 3.0 3 0 0 3 3 3 2 F-box-like Rifin_STEVOR PF02009.11 KNZ74309.1 - 0.038 13.6 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family stn_TNFRSF12A PF12191.3 KNZ74309.1 - 0.039 13.9 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain CcmD PF04995.9 KNZ74309.1 - 0.055 13.2 0.3 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF2207 PF09972.4 KNZ74309.1 - 0.19 10.3 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Thioesterase PF00975.15 KNZ74310.1 - 7.8e-09 36.0 0.0 9.9e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KNZ74310.1 - 2.7e-06 27.4 0.0 2.8e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DPBB_1 PF03330.13 KNZ74310.1 - 5.3e-05 23.1 0.0 9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Abhydrolase_5 PF12695.2 KNZ74310.1 - 0.0019 17.9 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Barwin PF00967.12 KNZ74310.1 - 0.0037 16.9 0.0 0.0048 16.5 0.0 1.1 1 0 0 1 1 1 1 Barwin family Isy1 PF06246.7 KNZ74311.1 - 4.5e-52 176.9 2.2 5e-52 176.8 1.5 1.0 1 0 0 1 1 1 1 Isy1-like splicing family UbiA PF01040.13 KNZ74313.1 - 1.2e-07 31.2 22.9 0.00057 19.1 12.1 2.2 1 1 1 2 2 2 2 UbiA prenyltransferase family DUF4660 PF15559.1 KNZ74314.1 - 0.066 13.2 0.2 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) PFK PF00365.15 KNZ74314.1 - 0.073 12.0 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Phosphofructokinase ORC2 PF04084.9 KNZ74314.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.4 1 1 0 1 1 1 0 Origin recognition complex subunit 2 DPBB_1 PF03330.13 KNZ74315.1 - 3.5e-05 23.7 0.0 6.7e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KNZ74315.1 - 0.0084 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Barwin family polyprenyl_synt PF00348.12 KNZ74318.1 - 2.2e-44 151.2 0.0 2.6e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase HEAT_2 PF13646.1 KNZ74319.1 - 1.2e-39 134.4 21.3 6.6e-08 32.7 0.0 14.7 9 4 3 12 12 12 8 HEAT repeats DUF3554 PF12074.3 KNZ74319.1 - 7.6e-37 127.5 1.6 9.6e-35 120.5 0.0 4.2 3 1 1 4 4 4 1 Domain of unknown function (DUF3554) HEAT_EZ PF13513.1 KNZ74319.1 - 5.5e-33 112.6 31.9 2.3e-05 24.7 0.1 18.4 14 3 6 20 20 20 9 HEAT-like repeat HEAT PF02985.17 KNZ74319.1 - 1.1e-32 109.1 10.1 0.099 12.7 0.0 18.9 21 0 0 21 21 20 8 HEAT repeat CLASP_N PF12348.3 KNZ74319.1 - 5.5e-14 52.0 0.0 0.0003 20.2 0.0 6.6 5 1 3 8 8 8 3 CLASP N terminal Ipi1_N PF12333.3 KNZ74319.1 - 1.3e-06 28.3 0.9 0.19 11.7 0.1 6.7 7 1 0 7 7 7 1 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.2 KNZ74319.1 - 3.8e-06 27.1 0.0 6.2 7.2 0.0 6.9 7 1 1 8 8 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KNZ74319.1 - 1.7e-05 23.3 4.1 3.4 5.8 0.0 6.6 7 1 0 7 7 7 1 Adaptin N terminal region Cohesin_HEAT PF12765.2 KNZ74319.1 - 0.0003 20.6 8.3 3.7 7.6 0.2 7.5 8 0 0 8 8 8 2 HEAT repeat associated with sister chromatid cohesion DUF3535 PF12054.3 KNZ74319.1 - 0.0021 16.7 0.0 0.33 9.5 0.0 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF3535) UME PF08064.8 KNZ74319.1 - 0.091 12.7 5.1 2.8 7.9 0.0 5.8 6 0 0 6 6 6 0 UME (NUC010) domain HEAT_PBS PF03130.11 KNZ74319.1 - 3.8 8.2 13.4 31 5.4 0.1 7.8 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat CTK3 PF12243.3 KNZ74320.1 - 3.7e-45 152.9 0.0 4.9e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KNZ74320.1 - 1.1e-14 54.1 15.2 3.1e-13 49.5 10.5 2.4 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Selenoprotein_S PF06936.6 KNZ74321.1 - 0.05 13.1 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) CoA_transf_3 PF02515.12 KNZ74322.1 - 3e-51 173.4 0.0 3.9e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Lactonase PF10282.4 KNZ74323.1 - 1.4e-50 172.3 0.0 1.6e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PrpF PF04303.8 KNZ74324.1 - 8.8e-76 255.0 0.6 2.5e-75 253.5 0.4 1.6 1 1 0 1 1 1 1 PrpF protein RVT_1 PF00078.22 KNZ74325.1 - 0.00018 20.9 0.2 0.00019 20.8 0.1 1.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_7 PF00840.15 KNZ74328.1 - 3.3e-221 734.1 23.7 4.4e-221 733.7 16.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 KNZ74328.1 - 2.4e-12 46.2 13.7 2.4e-12 46.2 9.5 4.0 5 0 0 5 5 5 1 Fungal cellulose binding domain Glyco_hydro_7 PF00840.15 KNZ74329.1 - 3.6e-219 727.4 20.5 4.2e-219 727.2 14.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Spt5_N PF11942.3 KNZ74332.1 - 0.022 15.3 6.9 0.022 15.3 4.8 2.4 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SGT1 PF07093.6 KNZ74332.1 - 0.054 11.8 8.2 0.07 11.5 5.7 1.1 1 0 0 1 1 1 0 SGT1 protein PGA2 PF07543.7 KNZ74332.1 - 0.2 11.4 13.5 1.2 8.9 4.8 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 MCRS_N PF13325.1 KNZ74332.1 - 0.61 9.5 6.0 1 8.8 4.2 1.3 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Senescence_reg PF04520.8 KNZ74332.1 - 1.5 9.3 10.7 2.9 8.3 7.4 1.5 1 1 0 1 1 1 0 Senescence regulator Abhydrolase_3 PF07859.8 KNZ74334.1 - 1.9e-27 96.2 0.0 2.7e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KNZ74334.1 - 2.3e-11 42.9 0.2 1.3e-10 40.5 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KNZ74334.1 - 0.0091 15.7 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ74334.1 - 0.19 10.8 0.1 0.3 10.2 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family F-box PF00646.28 KNZ74336.1 - 3.9e-05 23.1 0.2 9.7e-05 21.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KNZ74336.1 - 0.0059 16.3 0.1 0.023 14.4 0.0 2.1 2 0 0 2 2 2 1 F-box-like DUF1798 PF08807.5 KNZ74336.1 - 0.23 11.1 3.5 0.18 11.5 0.9 1.9 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) Glyoxal_oxid_N PF07250.6 KNZ74337.1 - 1.9e-52 177.7 0.0 1.1e-50 171.9 0.0 2.6 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KNZ74337.1 - 8.7e-16 57.8 0.0 1.7e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.1 KNZ74337.1 - 0.00039 20.4 0.1 21 5.4 0.0 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 KNZ74337.1 - 0.0037 16.9 4.8 1.5 8.6 0.0 4.8 5 0 0 5 5 5 1 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.6 KNZ74338.1 - 3.4e-53 180.2 0.0 1.6e-51 174.7 0.0 2.5 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KNZ74338.1 - 4e-20 71.7 0.5 1.3e-19 70.0 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.10 KNZ74338.1 - 0.0047 16.6 0.0 14 5.6 0.0 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 KNZ74338.1 - 0.23 11.2 12.6 3.2 7.5 0.0 5.8 6 1 1 7 7 7 0 Galactose oxidase, central domain COesterase PF00135.23 KNZ74339.1 - 1e-54 186.2 0.1 5.5e-48 163.9 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ74339.1 - 0.00021 20.9 0.0 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ74339.1 - 0.031 14.0 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ74339.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Cpn60_TCP1 PF00118.19 KNZ74343.1 - 4.7e-130 434.4 0.4 5.3e-130 434.2 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.12 KNZ74343.1 - 0.079 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor DUF1092 PF06485.6 KNZ74344.1 - 0.0052 15.7 0.4 0.0069 15.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1092) Pkinase PF00069.20 KNZ74345.1 - 1.1e-11 44.4 0.0 1.2e-09 37.6 0.0 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74345.1 - 0.00073 18.6 0.0 0.011 14.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase FAD_binding_3 PF01494.14 KNZ74346.1 - 5.8e-21 74.9 0.1 2.2e-20 73.0 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KNZ74346.1 - 3.4e-09 36.1 0.4 9.3e-09 34.6 0.3 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KNZ74346.1 - 2e-08 33.5 6.1 9.9e-07 27.9 2.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KNZ74346.1 - 3.6e-06 26.9 2.5 3.6e-06 26.9 1.7 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KNZ74346.1 - 5e-05 22.5 0.1 0.00011 21.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KNZ74346.1 - 0.00065 20.0 0.3 0.0034 17.7 0.1 2.3 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KNZ74346.1 - 0.00085 18.2 3.6 0.0025 16.7 2.2 1.9 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 KNZ74346.1 - 0.0019 16.8 1.0 0.19 10.3 0.7 2.3 1 1 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KNZ74346.1 - 0.0021 17.9 0.5 0.0049 16.7 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.4 KNZ74346.1 - 0.0023 17.6 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 Rossmann-like domain Amino_oxidase PF01593.19 KNZ74346.1 - 0.0034 16.5 0.8 0.0079 15.3 0.2 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase ApbA PF02558.11 KNZ74346.1 - 0.0084 15.5 0.9 0.016 14.6 0.6 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KNZ74346.1 - 0.011 15.4 0.7 0.02 14.6 0.5 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 KNZ74346.1 - 0.031 14.3 0.4 0.2 11.7 0.1 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KNZ74346.1 - 0.053 12.3 1.4 0.072 11.9 0.6 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KNZ74346.1 - 0.058 13.0 0.4 0.11 12.1 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 KNZ74346.1 - 0.083 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.9 KNZ74346.1 - 0.16 10.4 1.1 0.27 9.6 0.8 1.3 1 0 0 1 1 1 0 HI0933-like protein F-box PF00646.28 KNZ74348.1 - 0.00079 19.0 0.5 0.0029 17.2 0.2 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KNZ74348.1 - 0.083 12.6 1.4 0.19 11.5 0.3 2.1 2 0 0 2 2 2 0 F-box-like Lipase_GDSL PF00657.17 KNZ74350.1 - 6e-12 45.8 2.4 8.5e-12 45.3 1.7 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CBM_1 PF00734.13 KNZ74350.1 - 5.4e-08 32.3 9.4 2.1e-07 30.4 6.5 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Cys_rich_CWC PF14375.1 KNZ74351.1 - 0.025 14.5 0.2 0.041 13.8 0.1 1.5 1 1 0 1 1 1 0 Cysteine-rich CWC Mu-like_Com PF10122.4 KNZ74351.1 - 0.082 11.9 0.3 0.15 11.1 0.2 1.5 1 0 0 1 1 1 0 Mu-like prophage protein Com Helitron_like_N PF14214.1 KNZ74353.1 - 1.6e-16 60.5 0.0 2.2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 KNZ74355.1 - 2.9e-31 108.7 0.1 3.2e-31 108.5 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ74355.1 - 0.0008 19.0 0.0 0.00085 18.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KNZ74355.1 - 0.0081 15.7 0.1 0.0096 15.4 0.1 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KNZ74355.1 - 0.0085 15.9 0.0 0.0094 15.7 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 KNZ74355.1 - 0.0091 15.9 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF2791 PF10923.3 KNZ74355.1 - 0.028 13.0 0.0 0.033 12.7 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) ATP-synt_ab PF00006.20 KNZ74355.1 - 0.046 13.2 0.1 0.06 12.8 0.1 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 KNZ74355.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 KNZ74355.1 - 0.13 12.4 0.4 1 9.5 0.1 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KNZ74355.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KNZ74355.1 - 0.14 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein Herpes_Helicase PF02689.9 KNZ74356.1 - 5e-07 27.8 0.0 5.3e-07 27.8 0.0 1.0 1 0 0 1 1 1 1 Helicase Fez1 PF06818.10 KNZ74357.1 - 0.00038 20.5 7.9 0.00069 19.6 5.5 1.5 1 0 0 1 1 1 1 Fez1 DUF641 PF04859.7 KNZ74357.1 - 0.23 11.2 4.6 0.61 9.8 3.2 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) IncA PF04156.9 KNZ74357.1 - 0.57 9.7 14.7 0.26 10.8 8.5 1.6 2 0 0 2 2 2 0 IncA protein DUF4200 PF13863.1 KNZ74357.1 - 2.4 8.1 15.0 8.9 6.2 10.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Sec20 PF03908.8 KNZ74357.1 - 2.9 7.6 5.1 1.1 9.0 0.2 2.7 4 0 0 4 4 4 0 Sec20 Atg14 PF10186.4 KNZ74357.1 - 5.8 5.7 12.2 3.4 6.5 6.4 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 KNZ74357.1 - 7.9 6.1 11.6 55 3.3 8.1 2.2 1 1 0 1 1 1 0 Mnd1 family KR PF08659.5 KNZ74358.1 - 3.2e-06 26.9 0.0 9.8e-06 25.3 0.0 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KNZ74358.1 - 2.3e-05 24.3 0.0 6.4e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase WEMBL PF05701.6 KNZ74358.1 - 0.046 12.1 24.3 0.077 11.4 16.9 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light GAS PF13851.1 KNZ74358.1 - 0.31 10.2 29.5 0.4 9.8 9.3 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding tRNA_anti-codon PF01336.20 KNZ74359.1 - 0.046 13.5 0.1 11 5.9 0.0 2.7 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Peptidase_M22 PF00814.20 KNZ74359.1 - 0.19 11.2 0.0 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Glycoprotease family HSP70 PF00012.15 KNZ74359.1 - 0.52 8.1 0.0 3.6 5.3 0.0 2.3 3 0 0 3 3 3 0 Hsp70 protein Mito_carr PF00153.22 KNZ74362.1 - 2.3e-56 187.5 1.6 1.4e-19 69.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Alpha_L_fucos PF01120.12 KNZ74365.1 - 4.1e-77 259.4 4.5 5.6e-77 258.9 3.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase ARD PF03079.9 KNZ74366.1 - 3.4e-45 153.8 0.0 3.9e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 KNZ74366.1 - 6.9e-10 38.2 0.0 1.1e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KNZ74366.1 - 5.1e-06 26.2 0.0 8.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KNZ74366.1 - 5e-05 22.7 0.0 6.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Cupin DUF1846 PF08903.6 KNZ74366.1 - 0.052 11.9 0.0 0.068 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Cupin_3 PF05899.7 KNZ74366.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_8 PF13621.1 KNZ74366.1 - 0.095 12.1 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Cupin-like domain Cupin_6 PF12852.2 KNZ74366.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Cupin Pkinase PF00069.20 KNZ74367.1 - 3.4e-11 42.8 0.0 2.1e-09 36.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74367.1 - 0.0022 17.1 0.0 0.072 12.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase gag_pre-integrs PF13976.1 KNZ74368.1 - 5.8e-08 32.2 0.1 5.8e-08 32.2 0.1 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain rve PF00665.21 KNZ74368.1 - 0.0032 17.5 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain UBN2_3 PF14244.1 KNZ74368.1 - 0.005 16.4 0.0 0.0098 15.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 KNZ74369.1 - 5.8e-08 32.2 0.1 5.8e-08 32.2 0.1 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain rve PF00665.21 KNZ74369.1 - 0.0032 17.5 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain UBN2_3 PF14244.1 KNZ74369.1 - 0.005 16.4 0.0 0.0098 15.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Pkinase PF00069.20 KNZ74370.1 - 9.2e-12 44.6 0.0 2.3e-11 43.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74370.1 - 0.0074 15.3 0.0 0.032 13.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Protocadherin PF08374.6 KNZ74371.1 - 0.018 14.6 0.1 0.037 13.6 0.0 1.7 2 0 0 2 2 2 0 Protocadherin EphA2_TM PF14575.1 KNZ74371.1 - 0.084 13.2 0.2 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 KNZ74371.1 - 1.2 9.2 5.6 4.9 7.2 3.0 2.4 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Kdo PF06293.9 KNZ74372.1 - 3.1e-05 23.1 0.0 6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ74372.1 - 0.00023 20.9 0.0 0.00048 19.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ74372.1 - 0.0025 16.9 0.1 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.6 KNZ74372.1 - 0.013 14.7 0.1 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kinase-like PF14531.1 KNZ74372.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 KNZ74372.1 - 0.054 13.0 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RVP_2 PF08284.6 KNZ74373.1 - 0.0035 17.2 0.0 0.0053 16.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease FAD_binding_3 PF01494.14 KNZ74375.1 - 8.6e-25 87.5 0.0 9.3e-12 44.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 KNZ74375.1 - 0.0041 15.9 0.0 1.4 7.6 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.1 KNZ74375.1 - 0.02 14.9 0.2 0.046 13.7 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4481 PF14800.1 KNZ74376.1 - 0.62 8.9 5.5 1 8.1 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) Terpene_synth_C PF03936.11 KNZ74377.1 - 2.8e-15 56.2 0.0 3.5e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.6 KNZ74377.1 - 7.5e-05 21.5 0.1 0.00011 20.9 0.1 1.2 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) p450 PF00067.17 KNZ74378.1 - 1.3e-55 188.7 0.0 1.7e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KNZ74379.1 - 2.2e-21 76.0 53.2 5e-18 64.9 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Helitron_like_N PF14214.1 KNZ74380.1 - 1.1e-14 54.5 0.2 1.4e-14 54.2 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Gemini_AL1 PF00799.15 KNZ74380.1 - 0.0023 17.7 0.3 0.0027 17.5 0.2 1.1 1 0 0 1 1 1 1 Geminivirus Rep catalytic domain DUF3296 PF11726.3 KNZ74380.1 - 0.0042 16.6 0.3 0.0045 16.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) RNase_H PF00075.19 KNZ74381.1 - 0.00024 21.4 0.0 0.00034 20.9 0.0 1.5 1 1 0 1 1 1 1 RNase H L71 PF02448.10 KNZ74382.1 - 0.02 14.7 2.5 0.25 11.2 1.0 2.3 2 0 0 2 2 2 0 L71 family RNase_H_2 PF13482.1 KNZ74382.1 - 0.28 10.9 3.7 1.7 8.3 2.5 1.9 1 1 0 1 1 1 0 RNase_H superfamily DUF368 PF04018.8 KNZ74384.1 - 1.3 8.1 12.7 0.61 9.2 1.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF368) p450 PF00067.17 KNZ74385.1 - 5.6e-72 242.7 0.0 6.4e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 URO-D PF01208.12 KNZ74386.1 - 3.4e-125 417.5 0.0 3.9e-125 417.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DSPn PF14671.1 KNZ74387.1 - 1.2e-38 132.2 0.0 3.4e-37 127.5 0.0 2.4 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KNZ74387.1 - 1.1e-14 54.1 0.0 2.3e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KNZ74387.1 - 3.2e-05 23.4 0.0 5.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KNZ74387.1 - 0.00094 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KNZ74387.1 - 0.076 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF3699 PF12480.3 KNZ74387.1 - 0.087 12.4 0.2 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3699) Sugarporin_N PF11471.3 KNZ74388.1 - 0.11 12.1 0.3 0.13 11.9 0.2 1.1 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Arf PF00025.16 KNZ74392.1 - 0.018 14.2 0.4 0.021 14.0 0.3 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family CSTF_C PF14304.1 KNZ74393.1 - 0.079 12.2 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal zf-RVT PF13966.1 KNZ74395.1 - 2.4e-06 27.7 1.9 2.4e-06 27.7 1.3 1.8 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Succ_DH_flav_C PF02910.15 KNZ74395.1 - 0.097 12.5 0.2 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Fumarate reductase flavoprotein C-term Peptidase_C48 PF02902.14 KNZ74397.1 - 0.00017 21.3 1.8 0.00036 20.2 1.2 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain BCAS2 PF05700.6 KNZ74402.1 - 2.7 7.3 4.9 4.1 6.8 3.4 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF3722 PF12519.3 KNZ74406.1 - 1.7e-80 269.9 0.0 4.3e-80 268.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 KNZ74406.1 - 0.019 14.2 0.0 4.4 6.5 0.0 3.2 2 2 1 4 4 4 0 Eukaryotic porin LSM PF01423.17 KNZ74408.1 - 1.2e-16 59.9 0.0 1.4e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 KNZ74408.1 - 0.05 13.3 0.0 0.065 12.9 0.0 1.3 1 1 0 1 1 1 0 Gem-associated protein 7 (Gemin7) PPR_2 PF13041.1 KNZ74409.1 - 0.00076 19.4 0.0 2.3 8.2 0.0 3.6 4 0 0 4 4 4 2 PPR repeat family AAA PF00004.24 KNZ74410.1 - 1.4e-31 109.3 0.0 2e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KNZ74410.1 - 2.7e-11 43.7 0.0 5.4e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ74410.1 - 2.5e-07 31.5 0.0 5.5e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ74410.1 - 2.7e-07 30.7 0.7 9e-07 29.0 0.5 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KNZ74410.1 - 7.2e-06 25.9 0.0 1.6e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KNZ74410.1 - 8.2e-06 25.5 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 KNZ74410.1 - 1.1e-05 25.2 0.0 2.7e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 KNZ74410.1 - 1.2e-05 25.5 0.0 1.7e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNZ74410.1 - 1.5e-05 24.6 0.0 0.00013 21.6 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 KNZ74410.1 - 2e-05 24.5 0.0 4.1e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 KNZ74410.1 - 2.1e-05 24.0 0.2 0.0013 18.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 KNZ74410.1 - 3.1e-05 23.5 0.0 5.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 KNZ74410.1 - 6.1e-05 22.1 0.0 0.034 13.1 0.0 2.2 1 1 1 2 2 2 2 KAP family P-loop domain AAA_14 PF13173.1 KNZ74410.1 - 0.0001 22.2 0.0 0.0002 21.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KNZ74410.1 - 0.00012 21.2 0.0 0.00023 20.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.9 KNZ74410.1 - 0.00015 21.5 0.1 0.0005 19.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KNZ74410.1 - 0.00028 20.5 0.0 0.00074 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KNZ74410.1 - 0.0003 20.4 0.1 0.00079 19.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KNZ74410.1 - 0.00042 19.3 0.0 0.04 12.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 KNZ74410.1 - 0.00078 18.5 0.0 0.00092 18.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 KNZ74410.1 - 0.00098 18.5 0.0 0.0029 17.0 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.7 KNZ74410.1 - 0.00098 18.2 0.0 0.0026 16.8 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KNZ74410.1 - 0.001 19.1 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 KNZ74410.1 - 0.001 19.0 0.0 0.0028 17.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 KNZ74410.1 - 0.0014 18.2 0.0 0.0029 17.1 0.0 1.6 2 1 0 2 2 1 1 AAA domain PhoH PF02562.11 KNZ74410.1 - 0.0021 17.3 0.0 0.011 14.9 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein TIP49 PF06068.8 KNZ74410.1 - 0.0026 16.5 0.0 0.0038 15.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Viral_helicase1 PF01443.13 KNZ74410.1 - 0.0031 17.0 0.1 0.018 14.5 0.0 2.0 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 KNZ74410.1 - 0.01 16.1 0.0 0.013 15.7 0.0 1.3 1 1 0 1 1 1 0 ABC transporter AAA_3 PF07726.6 KNZ74410.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KNZ74410.1 - 0.014 15.6 0.0 0.024 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KNZ74410.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 KNZ74410.1 - 0.017 14.0 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.16 KNZ74410.1 - 0.019 14.1 0.1 0.053 12.6 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KNZ74410.1 - 0.025 13.6 0.1 0.3 10.1 0.0 2.1 1 1 0 1 1 1 0 KaiC CPT PF07931.7 KNZ74410.1 - 0.03 13.9 0.0 0.059 12.9 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein SRPRB PF09439.5 KNZ74410.1 - 0.032 13.4 0.0 0.25 10.5 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 KNZ74410.1 - 0.034 13.6 0.1 0.45 10.0 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein KTI12 PF08433.5 KNZ74410.1 - 0.037 13.2 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PduV-EutP PF10662.4 KNZ74410.1 - 0.043 13.2 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 KNZ74410.1 - 0.05 13.0 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.4 KNZ74410.1 - 0.051 12.2 0.0 0.34 9.4 0.0 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zot PF05707.7 KNZ74410.1 - 0.061 12.7 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) FtsK_SpoIIIE PF01580.13 KNZ74410.1 - 0.061 12.7 0.1 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 KNZ74410.1 - 0.079 12.6 0.0 0.54 9.9 0.0 2.1 2 0 0 2 2 2 0 NTPase Sigma54_activ_2 PF14532.1 KNZ74410.1 - 0.082 12.9 0.2 0.31 11.0 0.0 2.1 2 1 0 2 2 1 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 KNZ74410.1 - 0.099 12.5 0.0 0.43 10.4 0.0 2.0 2 1 0 2 2 2 0 Cytidylate kinase-like family Rad17 PF03215.10 KNZ74410.1 - 0.12 11.0 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 KNZ74410.1 - 0.12 12.3 0.1 0.46 10.4 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 KNZ74410.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sigma54_activat PF00158.21 KNZ74410.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain cobW PF02492.14 KNZ74410.1 - 0.13 11.6 0.1 0.58 9.5 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rdx PF10262.4 KNZ74411.1 - 5.3e-20 71.2 0.0 1e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Rdx family CLASP_N PF12348.3 KNZ74412.1 - 2.4e-71 239.7 1.1 1.6e-64 217.3 0.3 4.0 4 0 0 4 4 4 2 CLASP N terminal HEAT PF02985.17 KNZ74412.1 - 1.9e-07 30.5 3.1 0.47 10.6 0.0 5.9 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 KNZ74412.1 - 0.0031 17.9 5.1 4.3 7.9 0.0 4.8 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.2 KNZ74412.1 - 0.13 12.1 0.0 19 5.0 0.0 3.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Rhomboid PF01694.17 KNZ74413.1 - 5.1e-21 75.2 10.5 7.5e-21 74.6 7.3 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 KNZ74413.1 - 0.012 15.9 0.1 0.012 15.9 0.1 1.7 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Microvir_lysis PF04517.7 KNZ74413.1 - 5 6.9 6.4 0.88 9.3 1.4 1.9 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus Sedlin_N PF04628.8 KNZ74414.1 - 2.7e-28 98.4 0.0 3.7e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KNZ74414.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Sybindin-like family Activator_LAG-3 PF11498.3 KNZ74415.1 - 6.6 5.3 28.1 12 4.5 19.5 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Actin PF00022.14 KNZ74416.1 - 2e-89 299.7 0.0 2.5e-89 299.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KNZ74416.1 - 5.3e-05 21.9 0.0 0.12 10.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein BOP1NT PF08145.7 KNZ74417.1 - 3.1e-88 295.9 5.6 4.8e-88 295.2 3.9 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KNZ74417.1 - 7e-23 79.6 11.0 7.4e-07 28.8 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat TMEM61 PF15105.1 KNZ74418.1 - 0.2 11.1 2.3 5 6.6 0.1 2.2 2 0 0 2 2 2 0 TMEM61 protein family DUF2423 PF10338.4 KNZ74419.1 - 2.1e-13 49.9 4.6 3.8e-13 49.1 3.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) LSM PF01423.17 KNZ74420.1 - 3.1e-19 68.2 0.0 3.6e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KNZ74420.1 - 0.016 15.0 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain CBFD_NFYB_HMF PF00808.18 KNZ74421.1 - 1.4e-19 69.8 0.8 2.1e-19 69.3 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.11 KNZ74421.1 - 0.00067 19.4 0.1 0.00085 19.0 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 KNZ74421.1 - 0.011 15.7 0.1 0.016 15.3 0.1 1.4 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 MAP2_projctn PF08377.5 KNZ74421.1 - 0.018 12.6 0.7 0.018 12.6 0.5 1.0 1 0 0 1 1 1 0 MAP2/Tau projection domain MRP-S27 PF10037.4 KNZ74421.1 - 0.063 12.2 1.5 0.069 12.0 1.0 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 PfkB PF00294.19 KNZ74422.1 - 1.5e-12 47.3 0.0 2.1e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KNZ74422.1 - 0.045 12.9 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase ACPS PF01648.15 KNZ74423.1 - 1.8e-11 43.8 0.0 3.6e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily RNA_pol_Rpc34 PF05158.7 KNZ74424.1 - 1.3e-70 238.2 0.1 1.2e-59 202.1 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 KNZ74424.1 - 0.029 14.2 0.1 0.063 13.1 0.1 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HxlR PF01638.12 KNZ74424.1 - 0.029 13.9 0.1 0.058 13.0 0.1 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Macoilin PF09726.4 KNZ74424.1 - 0.18 10.0 14.3 0.25 9.5 9.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Asp_protease_2 PF13650.1 KNZ74426.1 - 0.0023 18.3 0.0 0.0037 17.7 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease Helitron_like_N PF14214.1 KNZ74429.1 - 8.3e-16 58.2 0.1 1e-15 57.9 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ74429.1 - 0.0046 16.5 0.0 0.0046 16.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) Gemini_AL1 PF00799.15 KNZ74429.1 - 0.012 15.4 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain PIF1 PF05970.9 KNZ74430.1 - 1.6e-63 214.8 0.1 2.3e-63 214.3 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 KNZ74430.1 - 0.024 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KNZ74430.1 - 0.026 14.0 0.2 0.064 12.7 0.1 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KNZ74430.1 - 0.029 14.3 0.0 0.088 12.7 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain Ku_C PF03730.9 KNZ74430.1 - 0.048 14.1 0.1 0.27 11.8 0.1 2.0 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm AAA_30 PF13604.1 KNZ74430.1 - 0.063 12.8 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain FIST PF08495.5 KNZ74430.1 - 0.076 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 FIST N domain PIF1 PF05970.9 KNZ74431.1 - 2.7e-29 102.2 0.2 3.1e-29 102.0 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase Pkr1 PF08636.5 KNZ74432.1 - 1.5e-09 37.7 7.4 1.9e-09 37.4 5.2 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF4191 PF13829.1 KNZ74432.1 - 0.004 16.3 0.4 0.0044 16.1 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) Spore_YabQ PF09578.5 KNZ74432.1 - 0.055 13.4 3.6 0.082 12.8 2.5 1.3 1 1 0 1 1 1 0 Spore cortex protein YabQ (Spore_YabQ) Sld5 PF05916.6 KNZ74433.1 - 2.6e-05 24.4 0.0 5.6e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 GINS complex protein Peptidase_C3 PF00548.15 KNZ74434.1 - 0.028 14.2 0.1 0.032 14.0 0.1 1.1 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Tau95 PF09734.4 KNZ74435.1 - 1.6e-58 198.5 0.0 2.1e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Aconitase PF00330.15 KNZ74439.1 - 3.6e-180 599.4 0.0 4.2e-180 599.1 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KNZ74439.1 - 3.6e-43 146.7 0.0 6e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF1237 PF06824.6 KNZ74441.1 - 2e-136 454.9 0.0 2.3e-136 454.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) C2 PF00168.25 KNZ74442.1 - 9.4e-11 41.4 0.0 3.6e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 C2 domain NT-C2 PF10358.4 KNZ74442.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 1 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins WD40 PF00400.27 KNZ74443.1 - 1.6e-16 59.4 0.2 0.0004 20.1 0.0 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat dUTPase PF00692.14 KNZ74444.1 - 4.3e-31 107.0 0.0 7e-31 106.3 0.0 1.3 1 0 0 1 1 1 1 dUTPase RNase_H PF00075.19 KNZ74446.1 - 8.8e-13 48.7 0.0 2.3e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 KNZ74446.1 - 3.4e-08 33.1 0.2 7.3e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KNZ74446.1 - 7.6e-08 32.5 0.2 1.8e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 KNZ74446.1 - 7.7e-07 29.3 0.1 2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF3336 PF11815.3 KNZ74447.1 - 3.6e-41 140.0 0.7 6.6e-41 139.2 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KNZ74447.1 - 7.1e-20 71.8 0.1 1.4e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TadE PF07811.7 KNZ74447.1 - 0.58 10.0 2.1 1.4 8.8 1.4 1.6 1 0 0 1 1 1 0 TadE-like protein DUF3759 PF12585.3 KNZ74448.1 - 5.1e-39 132.0 8.2 5.8e-39 131.8 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) ORC4_C PF14629.1 KNZ74450.1 - 3.3e-24 85.4 0.2 6.1e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 KNZ74450.1 - 5.4e-21 75.4 0.7 1e-19 71.2 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 KNZ74450.1 - 0.00017 21.3 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 KNZ74450.1 - 0.0015 18.6 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KNZ74450.1 - 0.0035 17.0 0.1 0.17 11.5 0.1 2.5 1 1 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 KNZ74450.1 - 0.028 14.2 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 KNZ74450.1 - 0.029 13.3 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.1 KNZ74450.1 - 0.058 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KNZ74450.1 - 0.062 13.5 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Med20 PF08612.6 KNZ74451.1 - 1e-08 34.6 0.0 3.5e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Sugar_tr PF00083.19 KNZ74458.1 - 6e-22 77.8 0.5 7.1e-22 77.5 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KNZ74458.1 - 0.063 11.4 0.6 0.081 11.0 0.4 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KNZ74458.1 - 0.089 11.4 2.2 0.17 10.5 1.5 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily HLH PF00010.21 KNZ74459.1 - 1.2e-05 24.8 0.0 2.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2423 PF10338.4 KNZ74459.1 - 0.093 12.7 0.8 0.21 11.5 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) DUF4477 PF14780.1 KNZ74459.1 - 0.15 11.4 0.1 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Atrophin-1 PF03154.10 KNZ74461.1 - 7.6e-05 21.0 8.5 7.6e-05 21.0 5.9 1.5 2 0 0 2 2 2 1 Atrophin-1 family Trypan_PARP PF05887.6 KNZ74461.1 - 2.6 7.8 21.4 1.5 8.6 2.4 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Ceramidase_alk PF04734.8 KNZ74462.1 - 9e-109 364.2 0.1 9.3e-44 149.3 0.0 3.4 1 1 2 3 3 3 3 Neutral/alkaline non-lysosomal ceramidase DUF2077 PF09850.4 KNZ74464.1 - 0.0095 15.3 0.8 0.021 14.2 0.5 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2077) RVP_2 PF08284.6 KNZ74466.1 - 0.0054 16.6 0.0 0.0061 16.4 0.0 1.3 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KNZ74466.1 - 0.0056 16.4 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ74466.1 - 0.0084 16.5 0.0 0.012 16.1 0.0 1.3 1 1 0 1 1 1 1 Aspartyl protease UbiA PF01040.13 KNZ74469.1 - 1.7e-06 27.4 1.6 1.9e-06 27.3 1.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family PP-binding PF00550.20 KNZ74470.1 - 5.7e-14 52.1 5.6 4.2e-07 30.1 0.7 2.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site Acyl_transf_1 PF00698.16 KNZ74471.1 - 2.1e-34 119.2 0.0 3.2e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KNZ74471.1 - 7.6e-20 71.2 0.0 1.2e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Aminotran_5 PF00266.14 KNZ74473.1 - 1.4e-12 47.0 0.0 1.9e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KNZ74473.1 - 0.053 12.5 0.0 6.4 5.6 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Chromo PF00385.19 KNZ74474.1 - 1.2e-06 28.1 0.3 1.8e-06 27.5 0.2 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Methyltransf_2 PF00891.13 KNZ74475.1 - 1.9e-31 109.1 0.0 3.1e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 KNZ74475.1 - 3.7e-07 29.8 0.0 9.6e-07 28.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ74475.1 - 7.8e-07 29.6 0.0 1.9e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 KNZ74475.1 - 3.1e-05 23.2 0.1 5.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_12 PF08242.7 KNZ74475.1 - 0.00015 22.1 0.0 0.00048 20.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ74475.1 - 0.00042 19.7 0.0 0.00089 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KNZ74475.1 - 0.00073 19.2 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ74475.1 - 0.036 14.0 0.0 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ74475.1 - 0.064 13.7 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PIF1 PF05970.9 KNZ74476.1 - 4.5e-95 318.6 0.1 9.6e-76 255.0 0.0 2.0 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KNZ74476.1 - 0.00023 20.8 0.0 0.00042 19.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 KNZ74476.1 - 0.04 14.0 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KNZ74476.1 - 0.06 12.8 0.2 0.13 11.7 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KNZ74476.1 - 0.079 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.10 KNZ74476.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit COPI_C PF06957.6 KNZ74477.1 - 0.13 10.7 8.5 0.14 10.6 5.9 1.0 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUF2146 PF10220.4 KNZ74477.1 - 0.36 8.7 5.7 0.38 8.6 4.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF1510 PF07423.6 KNZ74477.1 - 0.45 9.8 17.7 0.54 9.5 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 KNZ74477.1 - 0.7 9.7 3.1 0.88 9.4 2.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HGTP_anticodon2 PF12745.2 KNZ74477.1 - 1.4 7.9 9.8 2.2 7.3 6.8 1.4 1 1 0 1 1 1 0 Anticodon binding domain of tRNAs FAM60A PF15396.1 KNZ74477.1 - 2.4 7.8 6.4 2.8 7.6 4.4 1.0 1 0 0 1 1 1 0 Protein Family FAM60A AAA_28 PF13521.1 KNZ74479.1 - 0.25 11.2 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain NCD3G PF07562.9 KNZ74482.1 - 0.011 15.3 4.3 0.011 15.3 3.0 1.7 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR His_Phos_2 PF00328.17 KNZ74483.1 - 1.2e-41 143.1 0.0 1.6e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Herpes_gE PF02480.11 KNZ74484.1 - 0.0015 16.8 0.0 0.0024 16.2 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E IncA PF04156.9 KNZ74484.1 - 0.028 14.0 1.7 0.46 10.0 1.2 2.2 1 1 0 1 1 1 0 IncA protein FtsL PF04999.8 KNZ74484.1 - 4 7.2 5.4 5.4 6.8 0.3 2.5 2 0 0 2 2 2 0 Cell division protein FtsL Herpes_gE PF02480.11 KNZ74485.1 - 5.2e-05 21.7 0.0 9.7e-05 20.8 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E IncA PF04156.9 KNZ74485.1 - 0.00026 20.6 0.8 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 IncA protein Adeno_E3_CR2 PF02439.10 KNZ74485.1 - 0.0019 17.6 0.8 0.0041 16.6 0.5 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Yip1 PF04893.12 KNZ74485.1 - 0.03 13.8 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 Yip1 domain DUF1191 PF06697.7 KNZ74485.1 - 0.059 12.1 0.0 0.079 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4448 PF14610.1 KNZ74485.1 - 0.096 12.1 0.0 0.25 10.7 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DivIC PF04977.10 KNZ74485.1 - 0.22 11.0 7.4 0.65 9.5 0.3 2.5 2 0 0 2 2 2 0 Septum formation initiator Mnd1 PF03962.10 KNZ74485.1 - 0.35 10.5 1.7 0.56 9.8 1.2 1.3 1 0 0 1 1 1 0 Mnd1 family MerR-DNA-bind PF09278.6 KNZ74485.1 - 4.8 7.6 7.7 1.2 9.5 0.2 2.3 2 0 0 2 2 2 0 MerR, DNA binding Pyr_redox PF00070.22 KNZ74486.1 - 0.0014 18.9 0.0 0.003 17.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KNZ74486.1 - 0.017 14.0 0.0 2.4 6.9 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 KNZ74486.1 - 0.064 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SAGA-Tad1 PF12767.2 KNZ74487.1 - 0.034 13.8 9.3 0.051 13.2 6.4 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Asp_protease_2 PF13650.1 KNZ74488.1 - 0.0044 17.5 0.0 0.017 15.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease NSP10 PF09401.5 KNZ74488.1 - 0.045 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA synthesis protein NSP10 DUF3446 PF11928.3 KNZ74488.1 - 2.1 8.6 8.2 30 4.8 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3446) Asp_protease_2 PF13650.1 KNZ74491.1 - 0.00038 20.9 0.0 0.0011 19.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease NSP10 PF09401.5 KNZ74491.1 - 0.036 13.7 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA synthesis protein NSP10 Hexokinase_1 PF00349.16 KNZ74491.1 - 0.13 11.5 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Hexokinase PIF1 PF05970.9 KNZ74492.1 - 2e-36 125.7 0.0 2.2e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Viral_helicase1 PF01443.13 KNZ74492.1 - 0.0035 16.9 0.1 0.0087 15.5 0.1 1.7 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KNZ74492.1 - 0.01 15.3 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KNZ74492.1 - 0.029 14.5 0.1 0.13 12.4 0.1 1.9 1 1 0 1 1 1 0 RNA helicase Torsin PF06309.6 KNZ74492.1 - 0.086 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Torsin AAA_25 PF13481.1 KNZ74492.1 - 0.1 12.0 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Helitron_like_N PF14214.1 KNZ74493.1 - 5.2e-63 212.1 0.2 1.6e-62 210.5 0.1 1.9 3 0 0 3 3 3 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 KNZ74493.1 - 6.4e-06 25.1 0.0 0.073 11.7 0.0 2.3 2 0 0 2 2 2 2 Bacteriophage replication gene A protein (GPA) WCCH PF03716.9 KNZ74497.1 - 0.011 15.2 0.9 0.011 15.2 0.6 1.9 2 0 0 2 2 2 0 WCCH motif HA2 PF04408.18 KNZ74501.1 - 9.4e-19 67.3 0.1 2.2e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KNZ74501.1 - 1.5e-13 50.5 0.0 4.2e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KNZ74501.1 - 4.2e-11 42.5 0.0 1.6e-10 40.6 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KNZ74501.1 - 9.1e-11 41.5 0.0 2.1e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KNZ74501.1 - 0.0001 22.4 0.0 0.00028 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 KNZ74501.1 - 0.00053 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.1 KNZ74501.1 - 0.0008 19.1 0.2 0.002 17.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KNZ74501.1 - 0.0049 16.4 0.5 0.03 13.8 0.3 2.2 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KNZ74501.1 - 0.011 15.5 0.1 0.51 9.9 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase AAA_30 PF13604.1 KNZ74501.1 - 0.025 14.1 0.1 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KNZ74501.1 - 0.026 14.8 0.3 0.36 11.1 0.2 2.5 1 1 0 1 1 1 0 ABC transporter Helicase_RecD PF05127.9 KNZ74501.1 - 0.031 13.9 0.0 0.087 12.4 0.0 1.8 1 0 0 1 1 1 0 Helicase KaiC PF06745.8 KNZ74501.1 - 0.036 13.1 0.0 0.09 11.8 0.0 1.6 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 KNZ74501.1 - 0.039 13.1 0.1 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.1 KNZ74501.1 - 0.048 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 KNZ74501.1 - 0.055 12.3 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 KNZ74501.1 - 0.086 11.7 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KNZ74501.1 - 0.087 12.6 0.1 1.4 8.6 0.1 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Glyco_hydro_18 PF00704.23 KNZ74502.1 - 3e-11 43.3 1.2 4.2e-11 42.8 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Spo0M PF07070.6 KNZ74503.1 - 0.13 11.5 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 SpoOM protein Glyco_hydro_18 PF00704.23 KNZ74506.1 - 1.1e-10 41.5 4.1 2.4e-10 40.4 0.8 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Spc7 PF08317.6 KNZ74507.1 - 0.00053 18.7 1.0 0.00062 18.5 0.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Laminin_II PF06009.7 KNZ74507.1 - 0.0094 15.7 4.8 0.014 15.1 3.3 1.3 1 0 0 1 1 1 1 Laminin Domain II DHC_N1 PF08385.7 KNZ74507.1 - 0.018 13.4 0.7 0.021 13.2 0.5 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Myosin_tail_1 PF01576.14 KNZ74507.1 - 0.037 11.7 4.4 0.047 11.4 3.1 1.0 1 0 0 1 1 1 0 Myosin tail Act-Frag_cataly PF09192.5 KNZ74507.1 - 0.043 12.7 0.1 0.053 12.4 0.1 1.1 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Arfaptin PF06456.8 KNZ74507.1 - 0.045 13.0 1.3 0.06 12.6 0.9 1.1 1 0 0 1 1 1 0 Arfaptin-like domain CCDC155 PF14662.1 KNZ74507.1 - 0.047 13.2 6.2 0.056 13.0 4.0 1.3 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Latarcin PF10279.4 KNZ74507.1 - 0.11 12.7 0.7 0.19 11.9 0.5 1.5 1 0 0 1 1 1 0 Latarcin precursor IncA PF04156.9 KNZ74507.1 - 0.2 11.2 6.2 1.4 8.4 4.3 2.1 1 1 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 KNZ74507.1 - 0.59 10.2 3.5 0.95 9.5 2.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Tropomyosin PF00261.15 KNZ74507.1 - 0.64 9.0 6.5 12 4.9 3.2 1.9 1 1 0 1 1 1 0 Tropomyosin HisKA_3 PF07730.8 KNZ74507.1 - 0.66 10.3 4.2 27 5.2 0.1 3.0 1 1 2 3 3 3 0 Histidine kinase Vps5 PF09325.5 KNZ74508.1 - 1.1e-70 237.5 5.7 1.5e-70 237.1 4.0 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KNZ74508.1 - 2.7e-25 88.3 0.3 2.5e-24 85.2 0.0 2.2 2 0 0 2 2 2 1 PX domain BAR PF03114.13 KNZ74508.1 - 1.7e-07 30.9 2.8 2.6e-07 30.3 1.9 1.1 1 0 0 1 1 1 1 BAR domain BAR_3_WASP_bdg PF10456.4 KNZ74508.1 - 0.0009 18.5 1.5 0.09 12.0 0.1 2.2 1 1 1 2 2 2 2 WASP-binding domain of Sorting nexin protein Arfaptin PF06456.8 KNZ74508.1 - 0.0011 18.3 2.7 0.0022 17.3 1.9 1.4 1 1 0 1 1 1 1 Arfaptin-like domain MutS_III PF05192.13 KNZ74508.1 - 0.033 13.9 1.2 0.068 12.9 0.6 1.7 1 1 0 1 1 1 0 MutS domain III Met_asp_mut_E PF06368.6 KNZ74508.1 - 0.089 10.9 0.1 0.15 10.2 0.1 1.3 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) FAM92 PF06730.6 KNZ74508.1 - 0.5 9.6 6.2 1.4 8.2 4.3 1.6 1 1 0 1 1 1 0 FAM92 protein DWNN PF08783.6 KNZ74509.1 - 1.3e-28 98.7 0.1 2.9e-28 97.6 0.1 1.6 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 KNZ74509.1 - 1.6e-07 30.6 2.0 3.4e-07 29.6 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KNZ74509.1 - 9.6e-06 25.2 2.0 2e-05 24.2 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 KNZ74509.1 - 0.00028 20.8 8.5 0.00028 20.8 5.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.1 KNZ74509.1 - 0.0015 18.2 0.1 0.0032 17.1 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.10 KNZ74509.1 - 0.0025 17.7 0.0 0.0061 16.4 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-RING_2 PF13639.1 KNZ74509.1 - 0.0065 16.2 7.1 0.0065 16.2 4.9 1.8 2 0 0 2 2 2 1 Ring finger domain RHH_3 PF12651.2 KNZ74509.1 - 0.025 14.3 1.6 0.47 10.2 0.1 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix domain zf-CCHC_5 PF14787.1 KNZ74509.1 - 0.039 13.4 0.5 0.11 12.0 0.4 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-Nse PF11789.3 KNZ74509.1 - 0.55 9.7 4.6 1.5 8.3 3.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 KNZ74509.1 - 0.66 9.7 11.0 0.071 12.8 3.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ74509.1 - 1 9.0 8.4 2.3 7.9 5.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ74509.1 - 5.7 6.7 13.6 0.88 9.3 5.6 2.3 2 1 0 2 2 2 0 zinc-RING finger domain ERG4_ERG24 PF01222.12 KNZ74510.1 - 1.4e-119 399.5 23.7 1.7e-119 399.2 16.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family TPR_11 PF13414.1 KNZ74511.1 - 9.8e-12 44.3 0.7 4.5e-07 29.4 0.0 3.1 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 KNZ74511.1 - 1e-09 38.6 1.6 0.00018 21.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ74511.1 - 1.2e-09 37.9 4.7 0.14 12.8 0.0 6.3 3 2 2 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ74511.1 - 2.1e-08 33.4 0.0 0.058 13.3 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ74511.1 - 4.4e-08 33.5 0.6 0.00066 20.2 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ74511.1 - 1.3e-07 31.4 0.4 0.0047 16.8 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ74511.1 - 6e-07 28.8 0.0 0.27 11.1 0.0 4.7 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ74511.1 - 2e-05 23.9 0.0 0.19 11.4 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ74511.1 - 2.3e-05 24.2 0.0 0.0062 16.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KNZ74511.1 - 0.00015 21.8 0.0 0.14 12.2 0.0 2.7 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 KNZ74511.1 - 0.0024 17.8 0.3 0.031 14.2 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ74511.1 - 0.0062 16.4 0.1 1.2 9.2 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ74511.1 - 0.011 16.1 0.0 1.3e+02 3.3 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ74511.1 - 0.024 14.4 0.0 0.83 9.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 KNZ74511.1 - 0.088 12.1 0.0 3.7 6.9 0.0 2.4 1 1 1 2 2 2 0 26S proteasome subunit RPN7 KAR9 PF08580.5 KNZ74512.1 - 9.4e-08 30.8 29.6 3.1e-06 25.7 16.9 3.6 2 1 0 2 2 2 2 Yeast cortical protein KAR9 GAS2 PF02187.12 KNZ74512.1 - 0.0013 18.4 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain PAPA-1 PF04795.7 KNZ74512.1 - 0.11 13.1 1.2 0.19 12.4 0.0 2.0 2 0 0 2 2 2 0 PAPA-1-like conserved region MscS_porin PF12795.2 KNZ74512.1 - 0.14 11.4 6.5 2.3 7.4 0.6 3.2 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain IncA PF04156.9 KNZ74512.1 - 0.74 9.3 7.5 0.33 10.5 3.0 2.0 2 1 0 2 2 2 0 IncA protein Clr2 PF10383.4 KNZ74513.1 - 0.012 15.6 0.0 0.7 9.8 0.0 2.5 2 0 0 2 2 2 0 Transcription-silencing protein Clr2 MBOAT PF03062.14 KNZ74514.1 - 2.2e-10 40.2 5.4 2.2e-10 40.2 3.7 3.2 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KNZ74514.1 - 0.0049 16.9 0.9 0.025 14.6 0.1 2.5 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Sds3 PF08598.6 KNZ74515.1 - 6.1e-07 29.1 3.2 9.3e-07 28.5 2.2 1.5 1 1 0 1 1 1 1 Sds3-like Menin PF05053.8 KNZ74515.1 - 0.091 10.9 0.7 0.11 10.5 0.5 1.1 1 0 0 1 1 1 0 Menin F-box PF00646.28 KNZ74516.1 - 1.7e-05 24.3 0.1 3.5e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KNZ74516.1 - 0.00011 21.8 0.0 0.00026 20.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like DnaJ PF00226.26 KNZ74517.1 - 6.6e-26 89.8 0.9 1.1e-25 89.1 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 KNZ74517.1 - 2.7e-11 43.6 0.0 0.00036 20.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1977) hGDE_N PF14699.1 KNZ74518.1 - 0.018 14.8 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme WD40 PF00400.27 KNZ74519.1 - 1.8e-08 33.9 2.7 2.3 8.2 0.0 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat Pkinase PF00069.20 KNZ74520.1 - 2.2e-28 99.1 0.0 3.6e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74520.1 - 3e-26 92.0 0.0 5e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PAM2 PF07145.10 KNZ74520.1 - 0.0032 16.8 0.0 0.37 10.3 0.0 2.8 2 0 0 2 2 2 1 Ataxin-2 C-terminal region DOPA_dioxygen PF08883.6 KNZ74523.1 - 2.7e-12 46.6 0.0 3.3e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family StbA PF06406.6 KNZ74526.1 - 0.058 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 StbA protein Vezatin PF12632.2 KNZ74529.1 - 0.066 12.2 0.1 0.074 12.1 0.0 1.0 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes TFIIS_M PF07500.9 KNZ74530.1 - 9.3e-14 51.4 1.2 1.7e-13 50.6 0.8 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 KNZ74530.1 - 1.5e-10 40.5 7.7 2.6e-10 39.8 5.3 1.4 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.8 KNZ74530.1 - 0.00021 21.7 0.0 0.0006 20.2 0.0 1.8 1 0 0 1 1 1 1 SPOC domain PHD_2 PF13831.1 KNZ74530.1 - 0.3 10.4 2.5 0.57 9.5 1.7 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 KNZ74530.1 - 1.6 8.5 7.9 0.17 11.6 2.3 1.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 ADH_zinc_N PF00107.21 KNZ74531.1 - 1.9e-12 46.8 0.0 2.6e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ74531.1 - 5.1e-09 35.8 0.1 2.7e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Pyr_redox_3 PF13738.1 KNZ74531.1 - 0.038 14.0 0.2 0.12 12.4 0.1 1.7 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 KNZ74532.1 - 1.6e-53 181.5 0.1 3e-35 121.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74532.1 - 1.4e-24 86.6 0.1 3.1e-19 69.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KNZ74532.1 - 0.0011 18.0 0.2 0.0025 16.8 0.0 1.7 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KNZ74532.1 - 0.005 15.7 0.0 0.0083 15.0 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 KNZ74532.1 - 0.0061 15.6 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KNZ74532.1 - 0.021 14.1 0.1 0.06 12.6 0.0 1.7 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KNZ74532.1 - 0.024 14.3 0.3 0.29 10.8 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_C PF00433.19 KNZ74532.1 - 0.19 12.2 1.1 0.62 10.6 0.7 2.0 1 1 0 1 1 1 0 Protein kinase C terminal domain WD40 PF00400.27 KNZ74533.1 - 1.1e-53 177.2 8.7 1.2e-10 40.7 0.1 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 KNZ74533.1 - 9e-13 47.2 1.1 1.6e-12 46.4 0.8 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 KNZ74533.1 - 0.0014 17.8 0.0 7.2 5.6 0.0 3.2 2 1 1 3 3 3 3 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 KNZ74533.1 - 2.3 6.2 5.6 3.1 5.8 0.1 3.4 3 2 2 5 5 5 0 Nucleoporin Nup120/160 Ank PF00023.25 KNZ74534.1 - 6.6e-14 50.9 2.4 1.7e-06 27.5 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KNZ74534.1 - 1.7e-13 50.6 0.0 1.2e-07 31.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNZ74534.1 - 3.4e-12 46.5 0.6 1.8e-08 34.6 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KNZ74534.1 - 7.3e-12 45.1 0.2 3.9e-05 23.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ74534.1 - 2.8e-11 42.5 0.5 8.4e-05 22.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.8 KNZ74534.1 - 8.6e-05 22.1 0.2 0.0014 18.2 0.1 2.2 1 1 0 1 1 1 1 KilA-N domain IncA PF04156.9 KNZ74536.1 - 0.0021 17.7 1.5 0.0035 16.9 1.0 1.2 1 0 0 1 1 1 1 IncA protein PspA_IM30 PF04012.7 KNZ74536.1 - 0.12 11.7 3.0 0.35 10.1 0.7 2.2 2 0 0 2 2 2 0 PspA/IM30 family Atg14 PF10186.4 KNZ74536.1 - 2.6 6.9 4.3 4.8 6.0 3.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 An_peroxidase PF03098.10 KNZ74537.1 - 3.4e-76 256.7 0.0 4.1e-74 249.8 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KNZ74537.1 - 0.00021 19.9 0.0 0.00038 19.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Coatomer_E PF04733.9 KNZ74538.1 - 4.8e-38 130.9 0.1 6e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_14 PF13428.1 KNZ74538.1 - 5e-05 23.5 6.9 6.2 7.7 0.0 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ74538.1 - 0.00033 20.3 0.1 16 5.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KNZ74538.1 - 0.0033 17.6 6.0 1.1 9.8 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ74538.1 - 0.0086 15.9 3.4 0.041 13.7 0.0 3.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ74538.1 - 0.011 16.0 5.3 14 6.1 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ74538.1 - 0.022 14.3 0.0 3.8 7.2 0.0 3.2 3 0 0 3 3 3 0 TPR repeat PPR_3 PF13812.1 KNZ74538.1 - 0.033 14.4 0.1 4 7.9 0.0 3.5 3 0 0 3 3 3 0 Pentatricopeptide repeat domain OmpA PF00691.15 KNZ74538.1 - 0.071 13.5 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 OmpA family Metal_resist PF13801.1 KNZ74538.1 - 0.074 13.0 1.0 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Heavy-metal resistance F-box-like PF12937.2 KNZ74539.1 - 1.6e-12 46.8 0.5 4.2e-12 45.6 0.3 1.8 1 0 0 1 1 1 1 F-box-like DUF946 PF06101.6 KNZ74540.1 - 4.5e-17 61.2 2.6 6.6e-17 60.7 1.8 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) PI3_PI4_kinase PF00454.22 KNZ74541.1 - 1.1e-44 152.6 0.0 2.2e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KNZ74541.1 - 7.2e-10 38.1 0.0 2.1e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 FATC domain TAN PF11640.3 KNZ74541.1 - 2.6e-05 24.0 0.1 0.00012 21.8 0.0 2.3 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair DUF4407 PF14362.1 KNZ74541.1 - 0.035 13.0 0.6 0.07 12.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PALP PF00291.20 KNZ74542.1 - 3.8e-53 180.7 0.1 4.4e-53 180.5 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PALP PF00291.20 KNZ74543.1 - 1.7e-53 181.8 0.3 1.9e-53 181.6 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DOPA_dioxygen PF08883.6 KNZ74544.1 - 4.9e-31 106.8 0.3 6e-31 106.5 0.2 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family PH_10 PF15411.1 KNZ74545.1 - 3.2e-27 94.9 0.0 5.6e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 KNZ74545.1 - 1.9e-05 24.3 2.3 3.8e-05 23.4 1.6 1.5 1 0 0 1 1 1 1 Ring finger domain VWA_3 PF13768.1 KNZ74545.1 - 0.00054 19.6 0.6 0.0029 17.3 0.0 2.5 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_5 PF14634.1 KNZ74545.1 - 0.0063 16.2 1.2 0.015 15.0 0.9 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KNZ74545.1 - 0.015 15.4 0.1 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KNZ74545.1 - 0.059 13.0 1.6 0.11 12.1 1.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRP7 PF12923.2 KNZ74546.1 - 1.4e-32 112.5 3.4 1.4e-32 112.5 2.4 1.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 KNZ74546.1 - 8.8e-06 25.2 0.0 2.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myc_N PF01056.13 KNZ74546.1 - 0.0039 16.3 0.9 0.0039 16.3 0.6 1.7 2 0 0 2 2 2 1 Myc amino-terminal region RRM_6 PF14259.1 KNZ74546.1 - 0.0072 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PMT PF02366.13 KNZ74547.1 - 1.2e-80 270.4 17.2 2.3e-80 269.5 11.9 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KNZ74547.1 - 6.6e-14 51.8 3.8 8.7e-14 51.4 2.2 1.4 1 1 0 1 1 1 1 MIR domain PMT_2 PF13231.1 KNZ74547.1 - 1.3e-07 31.6 13.7 5.7e-07 29.5 9.5 2.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PX PF00787.19 KNZ74548.1 - 2.3e-15 56.3 0.0 4.9e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 PX domain NYD-SP28 PF14772.1 KNZ74548.1 - 0.92 9.6 6.0 1.3 9.1 0.2 3.0 3 1 0 3 3 3 0 Sperm tail DnaJ PF00226.26 KNZ74549.1 - 6.2e-16 57.8 1.8 1.9e-15 56.3 0.4 2.6 3 0 0 3 3 3 1 DnaJ domain OmpH PF03938.9 KNZ74549.1 - 6.9 6.5 17.4 2.8 7.8 9.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) E1-E2_ATPase PF00122.15 KNZ74550.1 - 2.5e-52 177.1 4.4 2.5e-52 177.1 3.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KNZ74550.1 - 1.2e-38 133.6 1.3 2.1e-38 132.8 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KNZ74550.1 - 3.9e-24 84.5 0.0 8.4e-12 45.0 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 KNZ74550.1 - 5.1e-09 36.5 0.0 2.6e-08 34.2 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KNZ74550.1 - 0.00013 21.6 0.3 0.042 13.4 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase p450 PF00067.17 KNZ74551.1 - 2e-60 204.6 0.8 9e-60 202.5 0.5 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF1771 PF08590.5 KNZ74551.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Sbi-IV PF11621.3 KNZ74552.1 - 0.01 15.9 1.3 21 5.3 0.0 3.8 3 1 1 4 4 4 0 C3 binding domain 4 of IgG-bind protein SBI Nif11 PF07862.6 KNZ74552.1 - 0.017 15.0 2.1 0.98 9.4 0.1 2.6 2 1 0 2 2 2 0 Nitrogen fixation protein of unknown function Nsp1_C PF05064.8 KNZ74552.1 - 0.04 13.5 2.1 4.1 7.0 0.0 3.3 3 1 1 4 4 4 0 Nsp1-like C-terminal region V_ATPase_I PF01496.14 KNZ74552.1 - 0.16 9.7 0.8 2.3 5.9 0.0 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family dsrm PF00035.20 KNZ74554.1 - 5.8e-07 30.0 0.0 9.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif RhoGAP PF00620.22 KNZ74555.1 - 1.3e-08 34.6 0.1 5.8e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KNZ74555.1 - 1.2e-07 31.7 0.0 3.6e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 KNZ74555.1 - 2.7e-07 30.2 0.0 4.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Histone PF00125.19 KNZ74556.1 - 7e-16 58.1 0.3 9.1e-16 57.7 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KNZ74556.1 - 0.038 14.0 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M50B PF13398.1 KNZ74557.1 - 2.5e-42 144.5 14.2 2.9e-42 144.3 9.8 1.0 1 0 0 1 1 1 1 Peptidase M50B-like DUF3366 PF11846.3 KNZ74557.1 - 0.059 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) 7tm_3 PF00003.17 KNZ74557.1 - 0.5 9.6 7.4 0.13 11.5 1.3 2.0 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Fis1_TPR_C PF14853.1 KNZ74558.1 - 2.7e-23 81.5 0.6 5.1e-23 80.6 0.4 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KNZ74558.1 - 6.4e-15 54.1 0.0 1.2e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 KNZ74558.1 - 0.028 14.3 0.3 0.068 13.1 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat RRM_1 PF00076.17 KNZ74559.1 - 2.2e-33 113.6 2.1 2e-15 56.1 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ74559.1 - 8e-24 83.4 0.0 1.5e-08 34.4 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ74559.1 - 4.6e-17 61.6 0.1 0.00018 21.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 KNZ74559.1 - 0.0097 15.9 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 2 Smg-4/UPF3 family DUF1903 PF08991.5 KNZ74560.1 - 9.2e-05 22.5 2.5 0.00013 22.0 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KNZ74560.1 - 0.0012 18.6 5.4 0.0018 18.1 3.7 1.3 1 0 0 1 1 1 1 CHCH domain COX6B PF02297.12 KNZ74560.1 - 0.0015 18.4 3.4 0.0021 18.0 2.4 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 KNZ74560.1 - 0.033 14.2 1.7 0.06 13.4 1.2 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 KNZ74560.1 - 0.11 12.4 2.2 0.3 10.9 1.5 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Amidase PF01425.16 KNZ74561.1 - 1.1e-99 334.3 0.0 1.3e-99 334.0 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF914 PF06027.7 KNZ74562.1 - 5.6e-107 357.4 10.4 6.9e-107 357.1 7.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 KNZ74562.1 - 0.00059 18.8 7.3 0.0023 16.8 5.2 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KNZ74562.1 - 0.19 11.7 27.8 0.16 12.0 4.9 3.2 2 1 1 3 3 3 0 EamA-like transporter family TPT PF03151.11 KNZ74562.1 - 0.48 10.0 17.9 0.25 10.9 0.3 2.6 3 0 0 3 3 3 0 Triose-phosphate Transporter family Selenoprotein_S PF06936.6 KNZ74563.1 - 0.12 11.9 1.2 0.16 11.4 0.8 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) SF3b1 PF08920.5 KNZ74564.1 - 1.8e-23 83.1 9.7 2.1e-22 79.7 6.7 2.7 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KNZ74564.1 - 4.3e-11 42.9 10.0 0.0001 22.4 0.0 7.0 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.17 KNZ74564.1 - 2.2e-10 39.6 7.6 0.025 14.6 0.0 9.6 10 0 0 10 10 10 1 HEAT repeat HEAT_EZ PF13513.1 KNZ74564.1 - 6.8e-09 35.9 3.1 0.047 14.1 0.0 8.2 7 2 2 9 9 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KNZ74564.1 - 8.4e-07 29.3 1.7 0.7 10.3 0.0 5.2 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KNZ74564.1 - 5.8e-06 24.8 1.5 0.057 11.7 0.0 3.3 2 1 1 3 3 3 3 Adaptin N terminal region NUC173 PF08161.7 KNZ74564.1 - 0.0006 19.2 0.3 10 5.3 0.0 4.5 4 1 1 5 5 5 2 NUC173 domain CLASP_N PF12348.3 KNZ74564.1 - 0.0019 17.5 1.7 2.8 7.2 0.0 3.7 3 1 0 3 3 3 2 CLASP N terminal Arm PF00514.18 KNZ74564.1 - 0.1 12.4 0.2 9.7 6.1 0.0 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 KNZ74564.1 - 0.27 11.0 4.8 70 3.2 0.0 5.0 7 0 0 7 7 7 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 KNZ74565.1 - 4.7e-138 460.7 9.1 6.1e-138 460.4 6.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KNZ74565.1 - 1.2e-19 70.7 0.7 2.5e-19 69.6 0.5 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KNZ74565.1 - 1.9e-06 28.0 0.6 0.19 12.0 0.0 4.7 3 2 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 KNZ74565.1 - 0.005 16.7 4.3 0.091 12.6 0.7 3.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KNZ74565.1 - 0.012 15.6 0.2 67 3.9 0.0 4.8 4 0 0 4 4 4 0 HEAT repeat TIP120 PF08623.5 KNZ74565.1 - 0.031 13.8 3.3 0.042 13.4 0.2 2.6 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) Microcin PF03526.8 KNZ74565.1 - 0.064 12.8 0.1 0.16 11.5 0.1 1.7 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein RIX1 PF08167.7 KNZ74565.1 - 0.065 12.9 2.7 0.35 10.5 0.0 3.4 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis Glyco_hydro_47 PF01532.15 KNZ74566.1 - 6.3e-120 400.8 0.0 2.4e-119 398.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Evr1_Alr PF04777.8 KNZ74567.1 - 3.8e-27 94.0 0.1 6.2e-27 93.3 0.0 1.4 2 0 0 2 2 2 1 Erv1 / Alr family Zip PF02535.17 KNZ74568.1 - 2.2e-53 181.3 9.0 2.6e-53 181.0 6.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter zf-HIT PF04438.11 KNZ74569.1 - 4.2e-09 35.8 10.0 4.2e-09 35.8 6.9 2.2 3 0 0 3 3 3 1 HIT zinc finger PolC_DP2 PF03833.8 KNZ74569.1 - 0.74 7.4 2.7 1 6.9 1.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DEAD PF00270.24 KNZ74570.1 - 6.4e-37 126.6 0.0 1.1e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ74570.1 - 4.8e-12 45.5 0.1 8.1e-10 38.4 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ74570.1 - 0.0032 17.3 0.1 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.9 KNZ74570.1 - 0.027 12.5 4.3 0.038 12.0 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.4 KNZ74570.1 - 4.3 6.0 12.6 0.098 11.4 4.1 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF3408 PF11888.3 KNZ74570.1 - 9.4 6.1 8.5 20 5.1 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Ribosomal_S10 PF00338.17 KNZ74571.1 - 1.2e-31 108.3 0.4 1.5e-31 108.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e FGGY_C PF02782.11 KNZ74572.1 - 3.8e-61 206.1 1.3 5.7e-61 205.5 0.9 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KNZ74572.1 - 4e-60 203.1 0.1 2.7e-58 197.1 0.1 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Glyco_hydro_47 PF01532.15 KNZ74573.1 - 2e-125 418.9 0.1 2.4e-125 418.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pox_G7 PF05503.7 KNZ74573.1 - 0.076 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus G7-like ANTH PF07651.11 KNZ74574.1 - 1.8e-47 161.3 0.0 3.9e-47 160.2 0.0 1.5 1 1 0 1 1 1 1 ANTH domain DUF1720 PF08226.6 KNZ74574.1 - 2.9e-05 24.0 29.8 2.9e-05 24.0 20.6 7.8 2 1 2 4 4 4 2 Domain of unknown function (DUF1720) ENTH PF01417.15 KNZ74574.1 - 0.00096 19.0 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 ENTH domain SHNi-TPR PF10516.4 KNZ74575.1 - 8.1e-17 60.1 0.2 6.8e-14 50.8 0.0 2.6 2 0 0 2 2 2 2 SHNi-TPR TPR_12 PF13424.1 KNZ74575.1 - 1.7e-13 50.2 6.7 3e-07 30.2 0.2 3.0 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ74575.1 - 1.8e-13 49.9 0.2 3.5e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 KNZ74575.1 - 4.1e-09 36.8 1.4 0.00046 20.7 0.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ74575.1 - 5.9e-07 28.8 3.5 0.017 14.7 0.4 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ74575.1 - 6.4e-06 25.6 8.6 0.037 13.9 0.4 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ74575.1 - 9.2e-05 21.9 0.4 1 9.3 0.0 3.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ74575.1 - 0.00016 21.9 11.8 0.05 13.9 0.1 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ74575.1 - 0.00097 18.7 3.2 0.24 11.2 0.0 3.8 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ74575.1 - 0.064 13.2 0.1 1.4 8.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ74575.1 - 0.095 13.3 7.5 6.8 7.6 0.0 4.5 4 1 1 5 5 4 0 Tetratricopeptide repeat DUF1664 PF07889.7 KNZ74575.1 - 0.12 12.1 0.6 0.37 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 KNZ74575.1 - 0.55 10.4 5.6 0.68 10.1 0.6 3.0 2 1 1 3 3 3 0 Syntaxin MIT PF04212.13 KNZ74575.1 - 4.7 7.1 8.8 0.58 10.0 0.1 3.6 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain Glyco_hydro_28 PF00295.12 KNZ74576.1 - 8.1e-40 136.7 14.8 9.7e-40 136.5 10.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.12 KNZ74577.1 - 7.7e-41 140.1 15.0 9.6e-41 139.7 10.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 RuvA_N PF01330.16 KNZ74577.1 - 0.064 13.0 0.0 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 RuvA N terminal domain Pectinesterase PF01095.14 KNZ74578.1 - 1.1e-41 142.4 6.1 1.4e-41 142.0 4.3 1.0 1 0 0 1 1 1 1 Pectinesterase zf-RING_2 PF13639.1 KNZ74579.1 - 1.2e-09 37.8 6.0 1.2e-09 37.8 4.1 3.8 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 KNZ74579.1 - 1.3e-08 34.3 4.7 1.3e-08 34.3 3.3 3.9 2 1 1 3 3 3 2 zinc-RING finger domain zf-C3HC4 PF00097.20 KNZ74579.1 - 5.3e-06 25.9 4.1 5.3e-06 25.9 2.8 4.7 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 KNZ74579.1 - 1.4e-05 24.8 35.1 3.9e-05 23.4 6.5 4.4 2 1 3 5 5 5 2 IBR domain zf-C3HC4_2 PF13923.1 KNZ74579.1 - 3.3e-05 23.8 5.3 3.3e-05 23.8 3.7 4.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KNZ74579.1 - 0.00039 20.0 1.7 0.00039 20.0 1.2 2.9 2 0 0 2 2 2 1 RING-type zinc-finger Aldedh PF00171.17 KNZ74580.1 - 3.6e-17 61.8 4.3 7.8e-13 47.5 1.9 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.6 KNZ74580.1 - 0.033 13.4 0.0 0.077 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) ATP-synt_ab PF00006.20 KNZ74581.1 - 4.8e-71 238.6 0.0 7.3e-71 238.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KNZ74581.1 - 1.2e-22 80.4 0.1 3.7e-22 78.9 0.0 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KNZ74581.1 - 7.5e-18 64.5 1.5 1.9e-17 63.1 1.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KNZ74581.1 - 0.053 13.4 0.4 0.16 11.8 0.2 1.9 2 1 0 2 2 2 0 HAS barrel domain Ribosomal_L21p PF00829.16 KNZ74582.1 - 1.5e-16 60.2 0.2 1.9e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Exo_endo_phos_2 PF14529.1 KNZ74584.1 - 6e-10 38.7 1.0 6e-10 38.7 0.7 1.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KNZ74584.1 - 6.1e-07 29.6 1.2 7.8e-07 29.2 0.8 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.19 KNZ74585.1 - 6.4e-06 26.5 0.1 1.5e-05 25.3 0.1 1.6 2 0 0 2 2 2 1 RNase H MMS19_N PF14500.1 KNZ74587.1 - 7.9e-90 300.6 0.0 1.6e-88 296.3 0.0 2.7 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 KNZ74587.1 - 5.7e-82 275.6 1.1 9.3e-81 271.6 0.3 2.5 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 KNZ74587.1 - 1.1e-05 25.6 2.5 0.18 12.1 0.0 5.7 4 1 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 KNZ74587.1 - 0.029 14.8 5.3 0.87 10.1 0.0 5.7 7 2 2 9 9 9 0 HEAT-like repeat HEAT PF02985.17 KNZ74587.1 - 0.47 10.6 2.6 90 3.5 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat Methyltransf_28 PF02636.12 KNZ74588.1 - 1.2e-36 126.4 0.0 1.7e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 KNZ74588.1 - 0.0042 17.5 0.0 0.02 15.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 KNZ74588.1 - 0.0086 15.1 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 KNZ74588.1 - 0.17 12.2 0.0 0.43 10.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ74589.1 - 4.1e-09 36.8 0.0 6.6e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ74589.1 - 5.7e-09 36.5 0.0 7.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ74589.1 - 5.3e-08 32.5 0.0 6.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ74589.1 - 3.9e-07 30.3 0.0 6.3e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KNZ74589.1 - 0.00076 18.8 0.0 0.0017 17.7 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.1 KNZ74589.1 - 0.0012 18.5 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 KNZ74589.1 - 0.03 13.7 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.13 KNZ74589.1 - 0.12 11.4 0.1 0.51 9.4 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Brix PF04427.13 KNZ74590.1 - 1.2e-28 100.0 0.2 1.7e-28 99.5 0.1 1.2 1 0 0 1 1 1 1 Brix domain Carn_acyltransf PF00755.15 KNZ74591.1 - 1.6e-127 426.0 0.0 1.8e-127 425.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AATase PF07247.7 KNZ74592.1 - 3.1e-10 39.2 0.0 3.3e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase ZZ PF00569.12 KNZ74593.1 - 4.3e-16 58.1 56.5 2.6e-06 26.8 4.2 6.1 6 0 0 6 6 6 4 Zinc finger, ZZ type PB1 PF00564.19 KNZ74593.1 - 1.4e-10 40.7 0.3 3.7e-10 39.3 0.1 1.9 2 0 0 2 2 2 1 PB1 domain Yippee-Mis18 PF03226.9 KNZ74593.1 - 0.068 13.2 0.3 0.068 13.2 0.2 4.2 5 0 0 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PHF5 PF03660.9 KNZ74594.1 - 1.6e-43 147.1 8.0 1.8e-43 146.9 5.5 1.0 1 0 0 1 1 1 1 PHF5-like protein PHD PF00628.24 KNZ74594.1 - 0.002 17.7 2.5 0.002 17.7 1.7 2.2 1 1 1 2 2 2 1 PHD-finger zinc-ribbons_6 PF07191.7 KNZ74594.1 - 0.017 14.8 4.3 0.017 14.8 3.0 2.0 1 1 0 1 1 1 0 zinc-ribbons zf-C4_ClpX PF06689.8 KNZ74594.1 - 2 7.9 11.0 1.3 8.6 0.4 2.9 3 0 0 3 3 3 0 ClpX C4-type zinc finger Prok-RING_1 PF14446.1 KNZ74594.1 - 6.1 6.6 14.5 9.5 6.0 5.1 2.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 HECT PF00632.20 KNZ74595.1 - 1.3e-82 277.5 0.0 2.2e-82 276.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Drf_GBD PF06371.8 KNZ74595.1 - 0.014 14.7 0.1 0.13 11.6 0.0 2.4 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain Arm PF00514.18 KNZ74595.1 - 0.031 14.0 1.0 0.61 10.0 0.0 3.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Aminotran_3 PF00202.16 KNZ74596.1 - 3e-62 210.4 0.0 9.6e-38 129.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-III DRMBL PF07522.9 KNZ74597.1 - 6.3e-28 97.0 0.0 1.7e-27 95.6 0.0 1.7 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KNZ74597.1 - 3.7e-10 39.6 0.0 6.9e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KNZ74597.1 - 0.043 13.4 1.6 0.094 12.3 1.1 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Ribosomal_S4e PF00900.15 KNZ74598.1 - 2.1e-30 104.1 0.3 5.7e-30 102.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 KNZ74598.1 - 2.1e-08 33.8 0.1 4.7e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 KNZ74598.1 - 6.3e-07 28.7 0.0 1.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KNZ74598.1 - 2.5e-05 23.8 5.3 5.4e-05 22.7 2.7 2.4 2 0 0 2 2 2 1 KOW motif zf-RING_2 PF13639.1 KNZ74599.1 - 2.1e-07 30.6 6.6 2.1e-07 30.6 4.6 3.7 2 1 1 3 3 3 1 Ring finger domain IBR PF01485.16 KNZ74599.1 - 4.4e-07 29.6 6.1 4.4e-07 29.6 4.2 3.6 2 1 1 3 3 3 1 IBR domain zf-RING_5 PF14634.1 KNZ74599.1 - 3.5e-06 26.6 7.0 3.5e-06 26.6 4.9 3.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KNZ74599.1 - 1.8e-05 24.6 8.2 1.8e-05 24.6 5.7 4.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ74599.1 - 0.0021 17.7 7.4 0.0021 17.7 5.1 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KNZ74599.1 - 0.0034 17.0 4.4 0.01 15.5 3.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger TPT PF03151.11 KNZ74600.1 - 1e-31 109.6 8.6 1e-31 109.6 6.0 1.9 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KNZ74600.1 - 8.2e-12 44.6 15.4 1.1e-11 44.2 10.6 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KNZ74600.1 - 4.9e-09 36.2 24.5 3e-05 24.0 1.4 3.5 2 1 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KNZ74600.1 - 0.00024 20.2 2.4 0.0091 15.1 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter DUF1576 PF07613.6 KNZ74600.1 - 4.7 6.6 15.5 0.018 14.5 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1576) Multi_Drug_Res PF00893.14 KNZ74600.1 - 8.5 6.9 11.9 2.8 8.4 1.0 3.3 2 1 1 3 3 3 0 Small Multidrug Resistance protein CRAL_TRIO PF00650.15 KNZ74601.1 - 1.3e-26 93.0 0.0 2.1e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KNZ74601.1 - 0.008 16.2 0.0 0.024 14.7 0.0 1.9 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain HIG_1_N PF04588.8 KNZ74601.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Hypoxia induced protein conserved region Ribosomal_L37ae PF01780.14 KNZ74603.1 - 3.7e-41 138.8 9.3 4.1e-41 138.7 6.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 KNZ74603.1 - 0.004 16.9 2.3 0.0057 16.4 1.6 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1364 PF07102.7 KNZ74603.1 - 0.0084 15.9 0.8 0.011 15.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) zf-BED PF02892.10 KNZ74603.1 - 0.053 13.2 2.8 1.1 9.0 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger zf-FCS PF06467.9 KNZ74603.1 - 0.072 12.7 1.1 0.81 9.3 0.1 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif GFA PF04828.9 KNZ74603.1 - 0.091 12.7 1.2 4.8 7.1 0.1 2.1 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme A2L_zn_ribbon PF08792.5 KNZ74603.1 - 0.18 11.3 3.9 0.75 9.3 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 KNZ74603.1 - 0.18 11.7 1.3 0.51 10.3 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 KNZ74603.1 - 0.19 11.4 2.4 0.34 10.6 1.6 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.1 KNZ74603.1 - 1.4 9.3 4.5 3.2 8.1 0.6 2.2 1 1 1 2 2 2 0 Zinc-finger double domain Ribosomal_L44 PF00935.14 KNZ74603.1 - 2 8.4 9.3 1.2 9.1 3.4 2.3 1 1 1 2 2 2 0 Ribosomal protein L44 Paf1 PF03985.8 KNZ74604.1 - 2.2e-45 155.2 0.0 3.1e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Paf1 GFO_IDH_MocA PF01408.17 KNZ74605.1 - 1.3e-23 83.7 0.0 2.7e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KNZ74605.1 - 0.0003 20.5 0.0 0.00064 19.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DXP_reductoisom PF02670.11 KNZ74605.1 - 0.13 12.8 0.0 0.41 11.1 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase WD40 PF00400.27 KNZ74606.1 - 1.5e-05 24.6 0.0 0.37 10.7 0.0 3.1 2 1 0 2 2 2 2 WD domain, G-beta repeat SET PF00856.23 KNZ74607.1 - 6e-09 36.4 0.1 2.4e-07 31.1 0.1 2.1 1 1 0 1 1 1 1 SET domain Complex1_LYR_1 PF13232.1 KNZ74608.1 - 3.8e-06 27.0 0.2 6.5e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KNZ74608.1 - 6.7e-05 22.5 0.9 0.00012 21.7 0.7 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) CNH PF00780.17 KNZ74609.1 - 5e-77 259.0 0.0 7.6e-77 258.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KNZ74609.1 - 6.1e-35 120.7 0.0 1e-34 120.0 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KNZ74609.1 - 9.4e-33 113.0 0.0 1.7e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.16 KNZ74609.1 - 1.2e-10 40.9 0.0 2.6e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Polysacc_deac_1 PF01522.16 KNZ74610.1 - 8.9e-30 102.8 0.0 1.4e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Sec1 PF00995.18 KNZ74611.1 - 1.4e-129 433.2 0.0 1.9e-129 432.8 0.0 1.2 1 0 0 1 1 1 1 Sec1 family AAA PF00004.24 KNZ74612.1 - 1.2e-42 145.2 0.0 2.4e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KNZ74612.1 - 1.5e-07 31.1 0.0 2.3e-06 27.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KNZ74612.1 - 3.8e-07 30.2 0.0 3.5e-05 23.8 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 KNZ74612.1 - 6.2e-06 26.2 0.0 2.2e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KNZ74612.1 - 8.4e-06 25.9 0.0 0.0014 18.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 KNZ74612.1 - 9.9e-06 24.7 0.0 2.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KNZ74612.1 - 2.9e-05 23.7 0.0 0.00017 21.2 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KNZ74612.1 - 0.00034 21.4 0.3 0.0013 19.5 0.0 2.2 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 KNZ74612.1 - 0.0016 17.4 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 KNZ74612.1 - 0.0018 18.5 0.1 0.024 14.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KNZ74612.1 - 0.0022 17.1 0.0 0.0048 16.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KNZ74612.1 - 0.0022 17.0 1.0 0.018 14.1 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 KNZ74612.1 - 0.0024 17.7 0.0 0.0065 16.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 KNZ74612.1 - 0.0028 16.4 0.0 0.0057 15.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 KNZ74612.1 - 0.003 17.0 0.1 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KNZ74612.1 - 0.0043 17.2 0.0 0.0084 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase DUF4200 PF13863.1 KNZ74612.1 - 0.0043 16.9 2.0 0.0087 16.0 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) AAA_14 PF13173.1 KNZ74612.1 - 0.0056 16.5 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KNZ74612.1 - 0.0062 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KNZ74612.1 - 0.011 15.2 0.0 0.044 13.2 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 KNZ74612.1 - 0.011 14.9 0.1 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 KNZ74612.1 - 0.013 15.1 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KNZ74612.1 - 0.013 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KNZ74612.1 - 0.016 14.5 0.3 0.064 12.6 0.1 1.9 1 1 1 2 2 2 0 AAA domain ResIII PF04851.10 KNZ74612.1 - 0.016 15.0 0.1 0.042 13.6 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 KNZ74612.1 - 0.017 15.4 1.7 5.7 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 KNZ74612.1 - 0.054 12.3 0.0 0.13 11.1 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 KNZ74612.1 - 0.055 12.5 1.1 0.16 11.0 0.0 2.2 3 0 0 3 3 3 0 KaiC NACHT PF05729.7 KNZ74612.1 - 0.057 13.0 0.0 0.18 11.4 0.0 1.8 1 1 1 2 2 2 0 NACHT domain AAA_30 PF13604.1 KNZ74612.1 - 0.057 13.0 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 KNZ74612.1 - 0.064 13.0 0.8 0.13 11.9 0.6 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_11 PF13086.1 KNZ74612.1 - 0.066 12.7 0.2 0.41 10.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KNZ74612.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 KNZ74612.1 - 0.12 11.9 0.0 0.44 10.1 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.1 KNZ74612.1 - 0.14 12.1 0.0 0.39 10.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_32 PF13654.1 KNZ74612.1 - 0.34 9.5 1.8 1.9 7.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain Peptidase_S10 PF00450.17 KNZ74613.1 - 9.1e-63 212.8 0.1 1.5e-62 212.1 0.1 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase SNF2_N PF00176.18 KNZ74613.1 - 0.078 11.7 0.0 0.097 11.4 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain GCFC PF07842.7 KNZ74614.1 - 1.6e-79 267.1 7.9 2e-79 266.8 5.1 1.4 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 KNZ74614.1 - 1e-13 51.3 20.4 1e-13 51.3 14.2 2.9 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch PF01585.18 KNZ74614.1 - 2.4e-12 46.4 1.4 5.6e-12 45.2 0.9 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KNZ74614.1 - 1.5e-06 27.9 0.4 1.5e-06 27.9 0.3 3.4 3 1 1 4 4 4 1 DExH-box splicing factor binding site CcmD PF04995.9 KNZ74615.1 - 0.28 10.9 1.1 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) WD40 PF00400.27 KNZ74616.1 - 6.7e-32 108.2 11.6 3.5e-11 42.5 0.5 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 KNZ74616.1 - 2.4e-27 94.7 9.9 5.6e-27 93.5 6.9 1.6 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.27 KNZ74617.1 - 4e-13 48.6 6.7 0.00046 19.9 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat FGGY_N PF00370.16 KNZ74618.1 - 4.7e-26 91.5 0.0 1.2e-15 57.5 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain PseudoU_synth_1 PF01416.15 KNZ74618.1 - 2e-18 66.7 0.0 1e-08 35.5 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase FGGY_C PF02782.11 KNZ74618.1 - 1.7e-15 57.1 0.0 3.1e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain RNA_pol_Rpb4 PF03874.11 KNZ74619.1 - 1.1e-21 76.9 0.9 1.5e-21 76.5 0.6 1.2 1 1 0 1 1 1 1 RNA polymerase Rpb4 DUF2666 PF10869.3 KNZ74619.1 - 0.086 12.8 0.3 0.35 10.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) Stm1_N PF09598.5 KNZ74621.1 - 0.032 14.9 1.1 0.052 14.2 0.8 1.3 1 0 0 1 1 1 0 Stm1 Aa_trans PF01490.13 KNZ74622.1 - 3.3e-67 226.7 24.5 5e-62 209.7 12.6 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein CDC27 PF09507.5 KNZ74622.1 - 1.2e-35 123.5 64.6 3.1e-34 118.9 44.8 2.6 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF202 PF02656.10 KNZ74624.1 - 0.00097 19.3 3.3 0.0012 19.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4401 PF14351.1 KNZ74624.1 - 0.0033 16.4 1.5 0.004 16.2 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) CopD PF05425.8 KNZ74624.1 - 0.036 14.2 4.5 0.043 14.0 0.0 2.1 2 0 0 2 2 2 0 Copper resistance protein D MTHFR PF02219.12 KNZ74625.1 - 1.7e-105 352.2 0.0 2.5e-105 351.6 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ELMO_CED12 PF04727.8 KNZ74626.1 - 4.2e-26 91.4 0.2 7.4e-26 90.6 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 KNZ74626.1 - 9.8e-17 61.1 0.5 7.4e-11 42.0 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3361) RCC1 PF00415.13 KNZ74628.1 - 5.3e-13 48.9 6.3 0.0021 18.2 0.0 6.7 6 1 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KNZ74628.1 - 7.8e-11 41.2 23.3 6.2e-06 25.6 0.6 6.1 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat zf-C2H2 PF00096.21 KNZ74629.1 - 0.056 13.7 0.4 0.17 12.2 0.3 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C3HC4 PF00097.20 KNZ74630.1 - 1.5e-05 24.5 13.2 3.1e-05 23.5 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ74630.1 - 0.00022 21.0 15.4 0.00055 19.7 10.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KNZ74630.1 - 0.00066 19.4 10.9 0.0056 16.5 7.7 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KNZ74630.1 - 0.0017 18.3 14.6 0.0038 17.2 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KNZ74630.1 - 0.0055 16.4 6.1 0.015 15.1 4.2 1.8 1 1 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KNZ74630.1 - 0.0071 16.0 13.5 0.016 14.8 9.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Baculo_IE-1 PF05290.6 KNZ74630.1 - 0.0071 16.0 1.2 0.012 15.3 0.9 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Tmpp129 PF10272.4 KNZ74630.1 - 0.008 14.9 2.8 0.013 14.2 2.0 1.4 1 0 0 1 1 1 1 Putative transmembrane protein precursor zf-C3HC4_3 PF13920.1 KNZ74630.1 - 0.076 12.7 10.2 0.21 11.2 7.0 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtt102p PF09510.5 KNZ74630.1 - 0.095 12.6 0.7 0.15 12.0 0.5 1.3 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein zf-rbx1 PF12678.2 KNZ74630.1 - 0.11 12.6 13.0 0.61 10.2 9.0 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 KNZ74630.1 - 0.59 9.7 8.2 1.9 8.1 5.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KNZ74630.1 - 0.82 9.5 9.2 2.3 8.1 6.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KNZ74630.1 - 5.3 6.8 8.7 18 5.1 6.0 2.1 1 0 0 1 1 1 0 RING-type zinc-finger Actin PF00022.14 KNZ74631.1 - 3.4e-24 85.0 0.0 7e-14 51.0 0.0 2.9 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KNZ74631.1 - 2.9e-05 22.8 0.1 6.2e-05 21.7 0.0 1.5 2 0 0 2 2 2 1 MreB/Mbl protein Peptidase_M20 PF01546.23 KNZ74633.1 - 2.2e-27 95.8 0.3 4e-27 94.9 0.2 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KNZ74633.1 - 6.4e-11 41.9 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KNZ74633.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 V-ATPase_G PF03179.10 KNZ74634.1 - 6e-34 116.5 14.3 7.3e-34 116.2 9.9 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit A_deaminase PF00962.17 KNZ74634.1 - 0.037 12.9 0.2 0.069 12.0 0.1 1.4 1 1 1 2 2 2 0 Adenosine/AMP deaminase DXP_synthase_N PF13292.1 KNZ74634.1 - 0.053 12.4 0.8 0.089 11.7 0.5 1.4 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase ATP-synt_F6 PF05511.6 KNZ74634.1 - 0.06 13.2 1.8 0.15 12.0 0.1 2.1 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 ATP-synt_B PF00430.13 KNZ74634.1 - 0.063 13.0 21.7 0.024 14.4 9.9 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Nop25 PF09805.4 KNZ74634.1 - 0.22 11.5 7.8 0.31 11.0 5.4 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF3552 PF12072.3 KNZ74634.1 - 0.5 9.5 16.9 1 8.5 8.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Exonuc_VII_L PF02601.10 KNZ74634.1 - 0.57 9.3 7.6 0.68 9.0 5.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.17 KNZ74634.1 - 2.3 8.2 9.0 7.1 6.6 6.1 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HrpE PF06188.7 KNZ74634.1 - 3 7.5 13.7 11 5.7 9.3 1.7 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Fungal_trans PF04082.13 KNZ74635.1 - 1.7e-18 66.4 3.7 2.5e-18 65.8 2.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_60s PF00428.14 KNZ74635.1 - 3.1e-17 62.7 9.4 5.8e-17 61.8 6.5 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Zn_clus PF00172.13 KNZ74635.1 - 2.4e-09 36.9 9.3 4.2e-09 36.1 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S19 PF00203.16 KNZ74636.1 - 2.6e-32 110.2 0.2 4.5e-32 109.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 KNZ74636.1 - 0.0015 18.3 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 Flagellar assembly protein FliH Symplekin_C PF12295.3 KNZ74637.1 - 1.1e-58 198.1 1.2 1.3e-57 194.6 0.1 2.7 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 KNZ74637.1 - 2.1e-52 177.9 0.1 4.9e-52 176.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) HEAT_2 PF13646.1 KNZ74637.1 - 0.0092 16.2 1.0 2.5 8.4 0.0 4.4 4 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 KNZ74637.1 - 0.084 13.3 0.7 14 6.3 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat Pkinase PF00069.20 KNZ74638.1 - 6.2e-57 192.7 0.0 1.4e-44 152.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74638.1 - 1.6e-25 89.7 0.0 2.6e-18 66.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KNZ74638.1 - 0.0023 17.7 2.6 0.11 12.2 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ74638.1 - 0.14 11.6 0.0 0.95 8.9 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase ParA PF10609.4 KNZ74639.1 - 2.8e-37 126.4 0.1 4.8e-37 125.6 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KNZ74639.1 - 2.3e-15 56.5 0.0 3.4e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 KNZ74639.1 - 6.4e-06 25.4 2.2 0.002 17.2 0.1 2.8 2 1 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.1 KNZ74639.1 - 0.00018 21.4 0.0 0.001 18.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KNZ74639.1 - 0.0003 20.2 0.2 0.00048 19.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KNZ74639.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Fer4_NifH PF00142.13 KNZ74639.1 - 0.018 14.2 0.0 0.51 9.4 0.0 2.3 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.6 KNZ74639.1 - 0.019 14.0 0.0 0.058 12.4 0.0 1.7 1 1 0 1 1 1 0 ATPase MipZ AAA_26 PF13500.1 KNZ74639.1 - 0.023 14.3 0.0 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain YhjQ PF06564.7 KNZ74639.1 - 0.033 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 YhjQ protein ArgK PF03308.11 KNZ74639.1 - 0.045 12.5 0.1 0.066 11.9 0.1 1.2 1 0 0 1 1 1 0 ArgK protein VirE PF05272.6 KNZ74639.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E UPF0179 PF03684.8 KNZ74639.1 - 0.099 12.2 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0179) AAA_29 PF13555.1 KNZ74639.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RhoGAP PF00620.22 KNZ74640.1 - 4.5e-34 117.2 0.0 8.9e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KNZ74640.1 - 1.9e-25 88.6 40.5 4e-11 42.8 5.7 4.6 4 0 0 4 4 4 4 LIM domain Fork_head PF00250.13 KNZ74641.1 - 5.8e-21 74.3 0.0 1.4e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Fork head domain Arteri_nucleo PF01481.11 KNZ74641.1 - 0.43 10.6 2.2 8.8 6.4 0.1 2.5 2 0 0 2 2 2 0 Arterivirus nucleocapsid protein Carboxyl_trans PF01039.17 KNZ74642.1 - 1.5e-46 158.8 0.0 2e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain DNA_ligase_A_M PF01068.16 KNZ74643.1 - 1e-52 178.4 0.1 1.7e-52 177.7 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KNZ74643.1 - 1.6e-41 142.0 0.6 4.8e-41 140.5 0.0 2.2 3 0 0 3 3 3 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KNZ74643.1 - 7.6e-12 45.4 0.0 2.4e-11 43.8 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KNZ74643.1 - 1.6e-11 44.2 0.6 9.6e-06 25.6 0.0 3.7 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.20 KNZ74644.1 - 1.1e-67 227.9 0.0 1.7e-67 227.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74644.1 - 1.8e-34 118.9 0.0 3.2e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ74644.1 - 0.00096 18.1 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KNZ74644.1 - 0.0089 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ74644.1 - 0.033 13.9 0.1 0.12 12.0 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ74644.1 - 0.12 11.9 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Dynein_light PF01221.13 KNZ74645.1 - 7.1e-29 99.6 0.1 9.1e-29 99.2 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 He_PIG PF05345.7 KNZ74646.1 - 1.3e-05 25.1 7.1 0.00053 19.9 2.4 3.9 4 0 0 4 4 4 2 Putative Ig domain HEAT_2 PF13646.1 KNZ74647.1 - 1.8e-15 56.9 2.7 0.011 15.9 0.0 5.9 4 3 2 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 KNZ74647.1 - 7.9e-14 51.6 13.9 0.00041 20.7 0.0 7.8 7 3 3 10 10 10 5 HEAT-like repeat HEAT PF02985.17 KNZ74647.1 - 8e-11 41.0 14.4 0.0073 16.3 0.0 7.5 8 0 0 8 8 8 3 HEAT repeat IBN_N PF03810.14 KNZ74647.1 - 1.8e-09 37.3 2.7 4.1e-09 36.2 0.2 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 KNZ74647.1 - 0.0002 21.6 0.0 0.28 11.5 0.0 3.5 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region GRIP PF01465.15 KNZ74647.1 - 0.032 13.7 0.0 3.6 7.1 0.0 3.0 2 0 0 2 2 2 0 GRIP domain Adaptin_N PF01602.15 KNZ74647.1 - 0.14 10.4 0.0 11 4.1 0.0 3.5 3 2 0 3 3 3 0 Adaptin N terminal region DHO_dh PF01180.16 KNZ74648.1 - 2.1e-94 315.7 0.0 2.6e-94 315.4 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 KNZ74648.1 - 0.041 12.7 0.0 0.27 10.0 0.0 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NMO PF03060.10 KNZ74648.1 - 0.17 11.0 0.1 0.69 8.9 0.0 1.9 2 0 0 2 2 2 0 Nitronate monooxygenase BTB PF00651.26 KNZ74649.1 - 1.7e-05 24.7 0.0 3.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain AIP3 PF03915.8 KNZ74650.1 - 9.7e-104 347.6 7.4 1.6e-103 346.9 5.1 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 DUF1720 PF08226.6 KNZ74650.1 - 0.00073 19.5 3.5 0.0019 18.1 2.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1720) ISG65-75 PF11727.3 KNZ74650.1 - 0.94 8.4 10.5 0.043 12.8 1.3 2.4 2 1 0 2 2 2 0 Invariant surface glycoprotein Prominin PF05478.6 KNZ74650.1 - 2.2 5.7 7.0 21 2.4 4.9 2.0 1 1 0 1 1 1 0 Prominin Metallophos PF00149.23 KNZ74651.1 - 1.9e-07 30.7 0.1 3.8e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KNZ74651.1 - 1.3e-05 25.0 0.3 2.8e-05 24.0 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L23 PF00276.15 KNZ74652.1 - 1.8e-09 37.3 0.3 5e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L23 LRR_4 PF12799.2 KNZ74653.1 - 3.8e-10 39.1 16.8 8.7e-08 31.6 0.7 3.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNZ74653.1 - 2.3e-09 36.8 7.0 2.4e-08 33.6 2.6 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KNZ74653.1 - 6.5e-09 34.6 7.1 0.011 15.6 0.2 5.6 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 KNZ74653.1 - 0.13 12.5 11.2 0.53 10.7 0.7 4.9 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 KNZ74653.1 - 0.32 11.1 2.5 24 5.3 0.2 3.7 3 0 0 3 3 3 0 Leucine Rich repeat zf-H2C2_2 PF13465.1 KNZ74654.1 - 5.5e-20 70.5 31.0 1e-07 31.8 0.3 5.7 7 0 0 7 7 6 3 Zinc-finger double domain zf-C2H2 PF00096.21 KNZ74654.1 - 6.9e-14 51.2 42.1 9.6e-05 22.4 1.3 7.3 8 1 0 8 8 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ74654.1 - 4.7e-09 35.9 26.9 0.0075 16.5 1.6 7.0 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KNZ74654.1 - 3.2e-06 27.1 11.6 0.081 13.0 0.5 5.2 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KNZ74654.1 - 4.3e-06 26.4 15.8 0.06 13.2 0.6 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KNZ74654.1 - 5.9e-05 23.0 16.5 0.015 15.5 2.0 5.3 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-met PF12874.2 KNZ74654.1 - 0.00011 22.2 14.3 0.14 12.3 1.0 5.5 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KNZ74654.1 - 0.0019 18.2 13.7 0.44 10.6 3.0 4.5 4 1 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KNZ74654.1 - 1 9.5 24.2 1.3 9.1 0.4 5.1 4 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding Cytochrom_CIII PF02085.11 KNZ74654.1 - 1.2 9.2 12.0 2.6 8.1 8.3 1.6 1 0 0 1 1 1 0 Class III cytochrome C family Zn_Tnp_IS1 PF03811.8 KNZ74654.1 - 5.3 6.6 9.0 1.1 8.8 3.0 2.2 2 0 0 2 2 2 0 InsA N-terminal domain C1_4 PF07975.7 KNZ74654.1 - 6.3 6.8 14.6 6.9 6.7 0.2 3.8 1 1 3 4 4 4 0 TFIIH C1-like domain zf-C2HC_2 PF13913.1 KNZ74654.1 - 6.4 6.5 9.7 13 5.5 0.0 4.1 5 0 0 5 5 5 0 zinc-finger of a C2HC-type CTP_transf_2 PF01467.21 KNZ74655.1 - 5.8e-10 39.4 0.0 1.2e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase CUE PF02845.11 KNZ74656.1 - 0.038 13.4 0.1 0.17 11.3 0.0 2.3 2 1 0 2 2 2 0 CUE domain FAD_binding_3 PF01494.14 KNZ74657.1 - 5.6e-50 170.3 0.0 2e-30 106.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DUF2962 PF11176.3 KNZ74658.1 - 5.4e-35 120.2 2.7 6.2e-35 120.0 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) MOZART1 PF12554.3 KNZ74659.1 - 5.1e-19 67.4 0.2 6.3e-19 67.1 0.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Zds_C PF08632.5 KNZ74660.1 - 5.6e-22 76.8 1.3 1e-21 76.0 0.9 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term RNA_pol_Rpc4 PF05132.9 KNZ74660.1 - 7.3 6.5 16.1 5.9 6.8 0.5 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 ACC_central PF08326.7 KNZ74661.1 - 8.6e-202 672.0 0.1 1.2e-200 668.2 0.0 2.0 2 0 0 2 2 2 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KNZ74661.1 - 2.2e-163 544.1 0.0 2.9e-163 543.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain P34-Arc PF04045.9 KNZ74661.1 - 1.5e-101 338.7 0.1 2.5e-101 338.0 0.1 1.4 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc CPSase_L_D2 PF02786.12 KNZ74661.1 - 3.9e-52 176.5 0.1 9.6e-52 175.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KNZ74661.1 - 6.8e-25 87.3 0.1 1.5e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KNZ74661.1 - 3.9e-21 75.0 0.0 3.2e-20 72.1 0.0 2.6 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KNZ74661.1 - 1.2e-15 56.9 0.0 3.7e-15 55.3 0.0 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KNZ74661.1 - 5.5e-12 45.7 0.1 1.3e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KNZ74661.1 - 0.00038 19.8 0.0 0.00087 18.7 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KNZ74661.1 - 0.0026 17.6 0.1 0.0078 16.0 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain CDC37_N PF03234.9 KNZ74661.1 - 0.31 11.3 3.2 6.1 7.1 0.7 2.7 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Epimerase PF01370.16 KNZ74662.1 - 1.7e-17 63.6 0.0 6.3e-17 61.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KNZ74662.1 - 4.3e-16 58.4 0.0 1.3e-15 56.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KNZ74662.1 - 1.1e-10 40.9 0.0 5.9e-08 31.9 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KNZ74662.1 - 1.7e-09 37.9 0.7 3.8e-09 36.7 0.5 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KNZ74662.1 - 6.2e-09 35.4 0.1 4.4e-07 29.3 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 KNZ74662.1 - 0.018 13.9 0.0 0.53 9.1 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein adh_short PF00106.20 KNZ74662.1 - 0.042 13.7 1.0 0.2 11.5 0.7 2.0 1 1 0 1 1 1 0 short chain dehydrogenase APH PF01636.18 KNZ74663.1 - 2.1e-10 40.7 0.0 3.5e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family rve PF00665.21 KNZ74665.1 - 0.00018 21.5 0.0 0.00023 21.2 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain F-box-like PF12937.2 KNZ74667.1 - 1.8e-07 30.7 1.2 5e-06 26.1 0.2 2.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KNZ74667.1 - 5.1 6.8 10.6 6.9 6.4 3.7 3.2 2 1 0 2 2 2 0 F-box domain DUF4038 PF13204.1 KNZ74668.1 - 0.018 14.4 0.1 0.02 14.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) RVP_2 PF08284.6 KNZ74668.1 - 0.029 14.2 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease DoxX_3 PF13781.1 KNZ74668.1 - 0.1 12.9 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 DoxX-like family Helitron_like_N PF14214.1 KNZ74670.1 - 0.00017 21.4 0.0 0.00018 21.2 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 KNZ74671.1 - 1.7e-22 79.9 0.0 2e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ74671.1 - 1.8e-07 30.9 0.0 3.3e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNZ74671.1 - 1.2e-05 24.9 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain TrwB_AAD_bind PF10412.4 KNZ74671.1 - 0.0023 16.6 0.0 0.0034 16.0 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.10 KNZ74671.1 - 0.0073 16.1 0.1 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KNZ74671.1 - 0.0075 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 KNZ74671.1 - 0.0078 15.8 0.0 0.056 13.0 0.0 1.9 1 1 1 2 2 2 1 AAA domain T2SE PF00437.15 KNZ74671.1 - 0.045 12.6 0.0 0.083 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 KNZ74671.1 - 0.046 13.9 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KNZ74671.1 - 0.058 12.2 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DEAD PF00270.24 KNZ74671.1 - 0.12 11.8 0.1 0.82 9.1 0.0 1.9 1 1 0 2 2 2 0 DEAD/DEAH box helicase HAMP PF00672.20 KNZ74672.1 - 0.013 15.6 0.0 0.067 13.3 0.0 2.0 2 0 0 2 2 2 0 HAMP domain DUF1882 PF08966.6 KNZ74672.1 - 0.019 14.9 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1882) APH PF01636.18 KNZ74673.1 - 0.0049 16.6 0.1 0.0098 15.6 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KNZ74673.1 - 0.054 12.6 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase APH PF01636.18 KNZ74674.1 - 0.098 12.3 0.5 0.37 10.4 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family FoP_duplication PF13865.1 KNZ74675.1 - 7.8 7.0 8.9 14 6.2 6.2 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Tannase PF07519.6 KNZ74678.1 - 1.8e-97 327.0 0.0 2.4e-97 326.6 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 KNZ74678.1 - 0.034 13.6 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold MAD PF05557.8 KNZ74680.1 - 2.3e-28 98.7 50.9 2.6e-28 98.5 3.2 2.3 1 1 1 2 2 2 2 Mitotic checkpoint protein Reo_sigmaC PF04582.7 KNZ74680.1 - 2 7.4 16.3 0.18 10.9 1.7 2.8 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Fucose_iso_N2 PF07882.7 KNZ74680.1 - 3.7 7.1 9.7 3.9 7.0 4.4 2.4 1 1 0 2 2 2 0 L-fucose isomerase, second N-terminal domain MT0933_antitox PF14013.1 KNZ74681.1 - 0.023 14.8 0.8 0.07 13.2 0.6 1.9 1 1 0 1 1 1 0 MT0933-like antitoxin protein LRR_4 PF12799.2 KNZ74682.1 - 0.031 13.9 5.1 15 5.3 0.1 4.7 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) SCIMP PF15050.1 KNZ74683.1 - 1.7 8.5 3.9 14 5.5 0.2 2.8 2 1 1 3 3 3 0 SCIMP protein Methyltransf_16 PF10294.4 KNZ74684.1 - 3.4e-15 55.9 0.0 4.6e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase DUF4217 PF13959.1 KNZ74684.1 - 0.00052 19.5 0.1 0.017 14.6 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) PrmA PF06325.8 KNZ74684.1 - 0.034 13.2 0.1 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KNZ74684.1 - 0.045 14.3 0.0 0.066 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain zf-CGNR PF11706.3 KNZ74685.1 - 0.0041 16.5 1.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 2 CGNR zinc finger Herpes_UL52 PF03121.10 KNZ74685.1 - 0.043 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase Glyco_hydro_16 PF00722.16 KNZ74687.1 - 1.8e-06 27.3 0.0 3.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 GTP_EFTU PF00009.22 KNZ74688.1 - 1.3e-48 164.9 0.0 2e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KNZ74688.1 - 2.2e-14 53.0 0.3 5.7e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KNZ74688.1 - 2.1e-05 24.5 4.8 0.0012 18.9 0.4 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KNZ74688.1 - 0.00011 22.0 0.1 0.00023 21.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 KNZ74688.1 - 0.01 15.6 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Elongation Factor G, domain II Miro PF08477.8 KNZ74688.1 - 0.013 15.9 0.0 0.12 12.8 0.0 2.3 2 1 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 KNZ74688.1 - 0.098 12.4 0.0 1 9.1 0.0 2.2 1 1 0 1 1 1 0 Dynamin family SRPRB PF09439.5 KNZ74688.1 - 0.12 11.5 0.2 8 5.6 0.1 2.3 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Hira PF07569.6 KNZ74690.1 - 0.0093 15.1 0.1 0.28 10.3 0.0 2.9 4 0 0 4 4 4 1 TUP1-like enhancer of split WD40 PF00400.27 KNZ74690.1 - 3.1 7.8 17.0 1.4 8.9 0.3 6.0 7 0 0 7 7 7 0 WD domain, G-beta repeat AAA_16 PF13191.1 KNZ74691.1 - 8.2e-11 42.2 0.3 6.7e-10 39.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KNZ74691.1 - 9.9e-09 35.0 0.0 2.2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 KNZ74691.1 - 4.8e-06 26.8 0.3 3.1e-05 24.1 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KNZ74691.1 - 6.9e-06 25.5 0.0 2.9e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KNZ74691.1 - 5.3e-05 23.3 0.1 0.00034 20.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KNZ74691.1 - 7.2e-05 22.5 0.1 0.00017 21.3 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase KAP_NTPase PF07693.9 KNZ74691.1 - 0.00088 18.3 3.3 0.041 12.8 0.2 2.9 2 1 1 3 3 3 2 KAP family P-loop domain RNA_helicase PF00910.17 KNZ74691.1 - 0.014 15.5 0.0 0.039 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 KNZ74691.1 - 0.033 13.3 0.0 1.7 7.7 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 KNZ74691.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KNZ74691.1 - 0.038 14.2 0.1 0.5 10.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain MitMem_reg PF13012.1 KNZ74691.1 - 0.079 13.0 0.3 0.21 11.6 0.2 1.7 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function NTPase_1 PF03266.10 KNZ74691.1 - 0.084 12.5 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 NTPase DSPc PF00782.15 KNZ74692.1 - 3e-06 26.8 0.0 4.4e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KNZ74692.1 - 0.0054 16.0 0.0 0.0054 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KNZ74692.1 - 0.068 12.6 0.0 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) F-box-like PF12937.2 KNZ74693.1 - 2.5e-08 33.5 0.2 1e-07 31.5 0.1 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ74693.1 - 0.057 13.0 1.0 14 5.4 0.0 2.8 2 0 0 2 2 2 0 F-box domain Peptidase_C14 PF00656.17 KNZ74695.1 - 1e-44 153.1 0.1 2.3e-43 148.6 0.0 2.2 1 1 0 1 1 1 1 Caspase domain TPR_9 PF13371.1 KNZ74695.1 - 0.15 11.9 0.0 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 KNZ74696.1 - 2.9e-20 72.5 0.0 3.7e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74696.1 - 8.5e-19 67.6 0.0 9.6e-19 67.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ74696.1 - 0.00021 20.3 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PBP PF01161.15 KNZ74697.1 - 1.2e-24 86.7 0.1 1.5e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein TPR_12 PF13424.1 KNZ74700.1 - 5.4e-281 907.4 52.7 8.3e-20 70.5 0.1 12.2 2 2 16 18 18 18 18 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ74700.1 - 2.1e-251 806.0 48.3 7.7e-15 54.2 0.0 20.3 20 0 0 20 20 20 19 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ74700.1 - 1.4e-51 172.0 22.0 1.9e-05 24.1 0.1 10.8 6 2 5 12 12 12 11 TPR repeat TPR_17 PF13431.1 KNZ74700.1 - 1.4e-45 149.7 21.7 0.053 13.7 0.0 18.8 19 0 0 19 19 19 13 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ74700.1 - 1.8e-43 142.9 29.7 0.03 14.2 0.0 18.8 19 0 0 19 19 18 11 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ74700.1 - 1.9e-41 139.8 20.0 0.001 19.6 0.0 10.6 6 1 7 13 13 13 12 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ74700.1 - 1.1e-39 132.3 31.7 0.031 13.8 0.0 18.8 19 0 0 19 19 19 9 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ74700.1 - 5.5e-35 116.3 43.0 0.093 12.5 0.0 17.7 18 0 0 18 18 18 11 Tetratricopeptide repeat PPR PF01535.15 KNZ74700.1 - 1.1e-15 56.4 9.1 12 6.0 0.0 16.0 17 0 0 17 17 17 0 PPR repeat TPR_4 PF07721.9 KNZ74700.1 - 5.7e-15 54.1 0.0 31 5.4 0.0 13.7 15 0 0 15 15 13 0 Tetratricopeptide repeat nec1 PF10379.4 KNZ74700.1 - 2.2e-13 49.9 3.9 6.4 6.0 0.0 11.9 3 1 10 15 15 15 1 Virulence protein nec1 TPR_8 PF13181.1 KNZ74700.1 - 4e-12 45.0 24.9 8.5 6.4 0.0 14.4 17 0 0 17 17 15 0 Tetratricopeptide repeat Patatin PF01734.17 KNZ74700.1 - 2.9e-10 40.4 0.0 1e-09 38.6 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase TPR_14 PF13428.1 KNZ74700.1 - 1e-05 25.7 55.7 20 6.1 0.1 17.3 13 4 5 18 18 18 0 Tetratricopeptide repeat Protein_K PF12283.3 KNZ74700.1 - 0.00013 21.7 27.2 15 5.5 0.1 13.1 16 1 1 17 17 17 0 Bacteriophage protein K Arch_ATPase PF01637.13 KNZ74700.1 - 0.003 17.2 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase PPR_1 PF12854.2 KNZ74700.1 - 0.0041 16.5 26.3 3.4 7.2 0.0 12.5 16 0 0 16 16 16 1 PPR repeat DUF1925 PF09094.6 KNZ74700.1 - 0.12 12.3 20.4 91 3.1 0.0 11.9 13 4 4 17 17 15 0 Domain of unknown function (DUF1925) DUF2670 PF10875.3 KNZ74700.1 - 0.16 11.9 0.2 10 6.1 0.0 3.8 4 1 2 6 6 4 0 Protein of unknown function (DUF2670) TroA PF01297.12 KNZ74700.1 - 0.63 9.2 4.0 31 3.6 0.1 4.5 4 2 1 5 5 5 0 Periplasmic solute binding protein family Pkinase PF00069.20 KNZ74702.1 - 2.3e-60 203.9 0.0 2.9e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74702.1 - 7.7e-27 93.9 0.0 9.8e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ74702.1 - 1.7e-07 30.5 0.0 2.4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ74702.1 - 0.012 15.3 0.6 0.028 14.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KNZ74702.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KNZ74702.1 - 0.14 10.9 0.1 0.21 10.3 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 TPR_12 PF13424.1 KNZ74705.1 - 4.7e-265 856.3 31.7 3.1e-20 71.8 0.1 13.8 1 1 14 17 17 17 17 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ74705.1 - 1.4e-262 841.4 39.5 4.3e-14 51.8 0.0 20.3 20 0 0 20 20 20 20 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ74705.1 - 3.1e-61 198.5 5.1 0.032 14.4 0.0 20.4 20 0 0 20 20 20 18 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ74705.1 - 7.2e-48 160.1 2.8 0.00022 20.7 0.1 11.7 6 2 8 15 15 15 14 TPR repeat TPR_2 PF07719.12 KNZ74705.1 - 1.6e-40 133.7 15.7 0.68 9.9 0.1 20.2 20 0 0 20 20 20 10 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ74705.1 - 1.1e-35 119.8 18.0 0.97 9.1 0.0 20.0 20 0 0 20 20 20 8 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ74705.1 - 7.2e-32 109.3 6.3 0.059 14.0 0.0 12.0 5 2 7 14 14 14 11 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ74705.1 - 8.3e-27 90.8 39.6 0.33 10.8 0.1 19.1 19 0 0 19 19 19 6 Tetratricopeptide repeat TPR_4 PF07721.9 KNZ74705.1 - 8e-19 66.0 0.0 82 4.0 0.0 16.8 18 0 0 18 18 18 0 Tetratricopeptide repeat Patatin PF01734.17 KNZ74705.1 - 1.7e-15 57.5 0.0 3.7e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Arch_ATPase PF01637.13 KNZ74705.1 - 0.0026 17.5 0.0 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase TPR_14 PF13428.1 KNZ74705.1 - 0.017 15.7 50.6 1e+02 3.9 0.1 17.8 16 4 4 20 20 20 0 Tetratricopeptide repeat TPR_3 PF07720.7 KNZ74705.1 - 1.2 8.9 37.8 7.7 6.4 0.1 14.0 20 0 0 20 20 17 0 Tetratricopeptide repeat IKKbetaNEMObind PF12179.3 KNZ74706.1 - 0.091 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain DUF2064 PF09837.4 KNZ74706.1 - 0.1 12.1 1.0 0.22 11.1 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) Muted PF14942.1 KNZ74706.1 - 0.78 9.6 6.9 1.5 8.6 4.8 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF572 PF04502.8 KNZ74706.1 - 4.9 6.2 16.5 7.5 5.6 11.4 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF572) Nop14 PF04147.7 KNZ74706.1 - 9.1 4.0 26.4 11 3.7 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family p450 PF00067.17 KNZ74707.1 - 3e-69 233.7 0.0 7.2e-69 232.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 KNZ74708.1 - 1.9e-61 207.4 0.1 2e-34 118.9 0.0 4.0 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74708.1 - 4.3e-32 111.2 0.0 3.5e-16 59.0 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 KNZ74708.1 - 1.8e-23 83.1 0.1 9.2e-23 80.7 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.1 KNZ74708.1 - 5.9e-10 38.7 0.0 5.9e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.18 KNZ74708.1 - 0.0045 16.7 1.6 0.015 15.0 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RWD PF05773.17 KNZ74708.1 - 0.0086 15.9 0.5 0.028 14.3 0.4 1.9 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.1 KNZ74708.1 - 0.045 12.7 0.0 0.12 11.3 0.0 1.7 1 0 0 1 1 1 0 Kinase-like Methyltransf_16 PF10294.4 KNZ74709.1 - 2e-20 72.9 0.0 3.2e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KNZ74709.1 - 3.8e-06 27.4 0.0 5.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ74709.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ74709.1 - 0.018 15.4 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KNZ74709.1 - 0.19 11.2 0.0 0.41 10.1 0.0 1.4 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Epimerase PF01370.16 KNZ74711.1 - 2.2e-05 24.0 0.1 0.095 12.1 0.0 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ74711.1 - 0.00085 19.3 0.3 0.0063 16.5 0.2 2.3 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KNZ74711.1 - 0.001 18.0 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Gemin7 PF11095.3 KNZ74711.1 - 0.046 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Epimerase PF01370.16 KNZ74712.1 - 3.7e-12 46.2 0.1 5.3e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KNZ74712.1 - 9.2e-11 40.9 0.0 1.4e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KNZ74712.1 - 2.1e-09 37.6 0.1 3.8e-09 36.8 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KNZ74712.1 - 0.0025 16.7 0.1 0.0038 16.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KNZ74712.1 - 0.065 13.1 0.0 0.21 11.4 0.0 1.8 1 1 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.16 KNZ74713.1 - 2.4e-12 46.8 0.3 1.1e-11 44.5 0.1 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ74713.1 - 2.6e-11 43.8 0.9 1.1e-10 41.8 0.3 2.4 2 1 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KNZ74713.1 - 7.5e-10 37.9 0.2 1.8e-09 36.7 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KNZ74713.1 - 8.3e-06 25.2 0.1 1.3e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Cytochrom_D1 PF02239.11 KNZ74713.1 - 0.0043 15.4 0.0 0.01 14.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome D1 heme domain Cohesin_load PF10345.4 KNZ74714.1 - 0.12 10.5 1.0 0.51 8.4 0.0 2.3 3 0 0 3 3 3 0 Cohesin loading factor NB-ARC PF00931.17 KNZ74714.1 - 0.17 10.6 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Epimerase PF01370.16 KNZ74715.1 - 2e-11 43.7 0.0 4.1e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ74715.1 - 4e-06 26.9 0.2 2.1e-05 24.6 0.2 2.2 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KNZ74715.1 - 1.3e-05 24.0 0.0 2.5e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KNZ74715.1 - 0.047 12.9 0.1 0.07 12.3 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 KNZ74715.1 - 0.11 12.4 0.5 8.3 6.2 0.1 2.6 2 1 1 3 3 3 0 short chain dehydrogenase 4HBT PF03061.17 KNZ74716.1 - 4.2e-10 39.6 0.0 6.5e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Pkinase_Tyr PF07714.12 KNZ74717.1 - 2e-43 148.3 0.0 2.6e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ74717.1 - 3.8e-42 144.2 0.0 5.2e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KNZ74717.1 - 0.018 14.0 0.0 0.051 12.5 0.0 1.6 1 1 0 1 1 1 0 Kinase-like F-box-like PF12937.2 KNZ74718.1 - 3.2e-06 26.7 2.1 3.2e-06 26.7 1.5 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KNZ74718.1 - 0.028 14.0 6.1 0.43 10.2 0.9 2.9 2 0 0 2 2 2 0 F-box domain Ribosomal_L7Ae PF01248.21 KNZ74719.1 - 1.2e-21 76.0 0.9 2.1e-21 75.2 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AAA PF00004.24 KNZ74720.1 - 2.3e-14 53.7 0.0 4.6e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KNZ74720.1 - 0.0059 16.7 1.1 0.42 10.7 0.0 3.0 1 1 2 3 3 3 1 AAA domain AAA_17 PF13207.1 KNZ74720.1 - 0.034 14.9 0.0 0.16 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KNZ74720.1 - 0.054 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.9 KNZ74720.1 - 0.076 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KNZ74720.1 - 0.11 12.5 0.0 0.34 10.8 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF2348 PF09807.4 KNZ74721.1 - 7e-14 51.5 0.1 2.2e-12 46.6 0.1 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) ERCC4 PF02732.10 KNZ74722.1 - 1.2e-22 80.1 0.0 2.8e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain Cir_N PF10197.4 KNZ74723.1 - 0.0021 18.0 0.3 0.0021 18.0 0.2 3.7 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Kri1 PF05178.7 KNZ74723.1 - 0.03 14.6 14.1 0.76 10.0 2.8 3.2 3 0 0 3 3 3 0 KRI1-like family Barttin PF15462.1 KNZ74723.1 - 2 8.0 5.6 1.2 8.7 1.2 2.0 1 1 1 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Pkinase PF00069.20 KNZ74724.1 - 2.6e-36 125.1 0.0 2.3e-25 89.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74724.1 - 1.3e-34 119.4 0.0 6.3e-19 68.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KNZ74724.1 - 0.0021 17.1 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ74724.1 - 0.037 13.7 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 KNZ74724.1 - 0.051 12.9 2.3 0.36 10.1 0.0 2.7 3 0 0 3 3 3 0 RIO1 family F-box-like PF12937.2 KNZ74725.1 - 1.1e-06 28.2 0.7 2.8e-06 26.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KNZ74725.1 - 0.00042 19.8 0.1 0.0012 18.4 0.1 1.8 1 0 0 1 1 1 1 F-box domain Pkinase_Tyr PF07714.12 KNZ74726.1 - 9.2e-28 97.0 0.0 1.3e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ74726.1 - 7.8e-27 94.0 0.0 1.3e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KNZ74726.1 - 0.0051 15.8 0.0 0.0076 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KNZ74726.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ74726.1 - 0.046 13.4 0.9 0.16 11.7 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family TFIIA PF03153.8 KNZ74727.1 - 7.2 6.3 7.3 7.6 6.3 5.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4218 PF13960.1 KNZ74728.1 - 0.045 13.2 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Atrophin-1 PF03154.10 KNZ74729.1 - 0.059 11.5 4.5 0.062 11.4 3.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family Pkinase PF00069.20 KNZ74730.1 - 2.9e-40 138.0 0.0 3.9e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74730.1 - 3.2e-36 124.7 0.0 9.7e-36 123.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ74730.1 - 1.3e-05 24.3 0.0 6.2e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KNZ74730.1 - 0.0001 21.4 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KNZ74730.1 - 0.0079 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KNZ74730.1 - 0.032 13.9 0.4 0.09 12.4 0.0 1.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ74731.1 - 1.5e-42 145.5 0.0 1.8e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74731.1 - 3.8e-39 134.3 0.0 5.1e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ74731.1 - 1.5e-06 27.3 0.0 2.3e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ74731.1 - 0.00074 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KNZ74731.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KNZ74731.1 - 0.0015 17.6 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1838 PF08894.6 KNZ74731.1 - 0.045 12.9 0.0 0.53 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1838) Pkinase PF00069.20 KNZ74732.1 - 2.8e-19 69.3 0.0 9.2e-14 51.2 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74732.1 - 3.2e-19 68.9 0.0 3.6e-13 49.1 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase PSP1 PF04468.7 KNZ74732.1 - 2.5e-11 43.3 1.1 8.7e-11 41.6 0.1 2.3 2 0 0 2 2 2 1 PSP1 C-terminal conserved region PBD PF00786.23 KNZ74733.1 - 3.5e-18 65.7 8.8 1.2e-10 41.6 1.3 2.6 3 0 0 3 3 3 2 P21-Rho-binding domain PH PF00169.24 KNZ74733.1 - 2e-10 40.8 0.0 4e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KNZ74733.1 - 0.067 13.4 0.2 2.2 8.5 0.1 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain G-alpha PF00503.15 KNZ74734.1 - 7.4e-96 321.1 1.3 2.5e-77 260.1 0.5 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 KNZ74734.1 - 7.3e-10 38.3 1.6 1.7e-05 24.1 0.0 2.9 3 1 0 3 3 3 2 ADP-ribosylation factor family Miro PF08477.8 KNZ74734.1 - 0.0012 19.2 0.0 0.64 10.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 KNZ74734.1 - 0.048 13.6 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KNZ74734.1 - 0.06 12.8 0.1 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Kelch_5 PF13854.1 KNZ74735.1 - 3.1e-15 55.7 0.1 3.3e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 KNZ74735.1 - 4.5e-12 45.5 1.0 7.3e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 KNZ74735.1 - 1.7e-11 43.4 1.5 0.0001 21.7 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 KNZ74735.1 - 2e-11 43.7 4.5 2.9e-07 30.4 0.0 3.4 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KNZ74735.1 - 2.5e-09 36.9 2.1 0.00023 21.2 0.3 2.3 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.10 KNZ74735.1 - 5.6e-07 29.0 0.9 0.0052 16.5 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Ricin_B_lectin PF00652.17 KNZ74736.1 - 1.6e-24 86.2 1.3 2e-24 85.9 0.9 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KNZ74736.1 - 3.9e-17 62.5 0.3 7.1e-09 35.9 0.1 2.6 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Pea-VEAacid PF08111.6 KNZ74736.1 - 0.02 14.9 0.1 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Pea-VEAacid family CDtoxinA PF03498.9 KNZ74736.1 - 0.028 13.7 1.0 0.19 11.1 0.0 2.0 1 1 1 2 2 2 0 Cytolethal distending toxin A/C family Ricin_B_lectin PF00652.17 KNZ74737.1 - 1.1e-24 86.7 1.6 1.4e-24 86.4 1.1 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KNZ74737.1 - 7.8e-18 64.7 0.3 3.8e-09 36.8 0.2 2.6 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Pea-VEAacid PF08111.6 KNZ74737.1 - 0.0074 16.2 0.1 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Pea-VEAacid family CDtoxinA PF03498.9 KNZ74737.1 - 0.015 14.6 0.8 0.13 11.6 0.0 2.1 1 1 1 2 2 2 0 Cytolethal distending toxin A/C family DUF4598 PF15370.1 KNZ74738.1 - 4.8e-09 36.4 0.1 1.3e-08 35.1 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4598) PP1c_bdg PF10488.4 KNZ74738.1 - 0.0089 15.2 0.1 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatase-1 catalytic subunit binding region Beta-Casp PF10996.3 KNZ74738.1 - 0.055 13.4 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Beta-Casp domain DUF3840 PF12944.2 KNZ74738.1 - 0.097 12.5 0.2 6.9 6.5 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3840) Chromo PF00385.19 KNZ74740.1 - 5.7e-16 57.9 0.5 7e-16 57.6 0.3 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KNZ74740.1 - 0.009 15.7 0.9 0.011 15.3 0.6 1.2 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Mtf2_C PF14061.1 KNZ74740.1 - 0.039 13.8 0.1 0.052 13.4 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Ribonuc_2-5A PF06479.7 KNZ74741.1 - 0.00078 19.2 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease 2-5A RCC1 PF00415.13 KNZ74742.1 - 9.7e-32 108.9 12.7 3.6e-06 27.0 0.0 7.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KNZ74742.1 - 1.7e-14 52.9 29.2 0.0001 21.7 0.1 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 KNZ74742.1 - 4.1e-09 36.0 5.6 4.1e-09 36.0 3.9 2.6 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 KNZ74742.1 - 0.0012 18.5 1.1 0.0036 17.0 0.8 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PBP1_TM PF14812.1 KNZ74742.1 - 0.0013 18.9 4.0 0.0013 18.9 2.8 3.6 5 0 0 5 5 5 1 Transmembrane domain of transglycosylase PBP1 at N-terminal PHD_2 PF13831.1 KNZ74742.1 - 2 7.7 11.9 1.5 8.1 0.9 3.7 3 0 0 3 3 3 0 PHD-finger GMC_oxred_N PF00732.14 KNZ74743.1 - 3.3e-69 233.3 0.0 4.2e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ74743.1 - 5.4e-33 114.3 0.0 8.7e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KNZ74743.1 - 0.0005 20.0 0.0 0.002 18.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KNZ74743.1 - 0.0022 16.8 0.7 0.032 13.0 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KNZ74743.1 - 0.0025 16.7 0.1 0.0041 16.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KNZ74743.1 - 0.0061 15.6 0.0 0.0098 15.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KNZ74743.1 - 0.01 15.8 0.0 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KNZ74743.1 - 0.011 14.7 0.0 0.031 13.1 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.13 KNZ74743.1 - 0.068 13.1 0.1 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Lipase_GDSL PF00657.17 KNZ74744.1 - 1.7e-06 28.0 0.0 7.3e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KNZ74744.1 - 0.00044 20.4 1.9 0.00093 19.3 1.3 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_92 PF07971.7 KNZ74745.1 - 1.4e-110 370.3 0.0 1.7e-110 370.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 GMC_oxred_N PF00732.14 KNZ74746.1 - 3.9e-62 210.0 0.0 5e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ74746.1 - 4.4e-36 124.3 0.7 1.2e-35 122.8 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KNZ74746.1 - 0.00021 21.2 0.0 0.0006 19.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KNZ74746.1 - 0.00021 20.3 0.0 0.00032 19.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KNZ74746.1 - 0.001 18.0 0.0 0.0083 15.0 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ74746.1 - 0.0068 15.3 0.1 0.16 10.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KNZ74746.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KNZ74746.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 KNZ74746.1 - 0.17 10.3 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Hamartin PF04388.7 KNZ74747.1 - 3.5 6.2 8.8 4.1 5.9 6.1 1.0 1 0 0 1 1 1 0 Hamartin protein UBN2_2 PF14227.1 KNZ74748.1 - 7.7e-12 44.8 0.0 1.7e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ74748.1 - 4.4e-08 32.9 0.0 1.7e-07 31.0 0.0 1.9 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KNZ74748.1 - 0.00069 19.4 0.4 0.0013 18.5 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF4219 PF13961.1 KNZ74748.1 - 0.032 13.6 0.1 0.067 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Methyltransf_15 PF09445.5 KNZ74749.1 - 1.3e-39 135.3 0.0 4.6e-29 101.0 0.0 2.1 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KNZ74749.1 - 4e-09 36.5 0.0 7.6e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ74749.1 - 6.8e-09 36.2 0.0 2.5e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ74749.1 - 1.1e-05 25.0 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KNZ74749.1 - 1.9e-05 24.3 0.0 3.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 KNZ74749.1 - 2.6e-05 24.4 0.0 6.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KNZ74749.1 - 3.4e-05 23.5 0.0 5.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 KNZ74749.1 - 7.5e-05 22.2 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 KNZ74749.1 - 0.0027 18.1 0.0 0.0077 16.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KNZ74749.1 - 0.004 16.3 0.0 0.0074 15.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) U1snRNP70_N PF12220.3 KNZ74749.1 - 0.012 15.8 0.7 1.1 9.6 0.2 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal tRNA_U5-meth_tr PF05958.6 KNZ74749.1 - 0.034 12.8 0.0 0.047 12.3 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase ADH_zinc_N PF00107.21 KNZ74749.1 - 0.086 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SAM_MT PF04445.8 KNZ74749.1 - 0.089 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase FAD_binding_3 PF01494.14 KNZ74750.1 - 7.4e-18 64.7 0.0 4.3e-08 32.6 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 KNZ74750.1 - 6.4e-06 25.0 1.0 0.0003 19.5 0.0 3.1 3 1 1 4 4 4 1 Tryptophan halogenase NAD_binding_8 PF13450.1 KNZ74750.1 - 4.5e-05 23.3 0.3 0.00017 21.5 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KNZ74750.1 - 0.0088 14.8 0.0 0.043 12.6 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 KNZ74750.1 - 0.046 12.6 1.0 0.16 10.8 0.6 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 KNZ74750.1 - 0.13 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KNZ74750.1 - 0.33 10.8 0.9 0.57 10.0 0.7 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Nup35_RRM PF05172.8 KNZ74751.1 - 2.4e-08 33.6 0.0 1.5e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 KNZ74751.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HeLo PF14479.1 KNZ74751.1 - 0.16 11.7 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation RRM_6 PF14259.1 KNZ74752.1 - 3.9e-05 23.5 0.0 0.00011 22.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KNZ74752.1 - 0.00017 21.1 0.1 0.0005 19.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M28 PF04389.12 KNZ74754.1 - 1.4e-27 96.6 0.1 2.5e-27 95.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 PTPA PF03095.10 KNZ74755.1 - 2.2e-115 384.9 0.0 2.8e-115 384.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RNA_pol_Rpo13 PF12136.3 KNZ74756.1 - 0.56 9.9 6.5 1.2 8.8 4.5 1.5 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain GMC_oxred_N PF00732.14 KNZ74757.1 - 5.1e-62 209.6 0.0 6.6e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ74757.1 - 2.9e-35 121.6 0.9 6.5e-35 120.5 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KNZ74757.1 - 0.00022 21.1 0.0 0.00065 19.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KNZ74757.1 - 0.00023 20.2 0.0 0.00035 19.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KNZ74757.1 - 0.0021 17.0 0.1 0.0091 14.9 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ74757.1 - 0.0072 15.2 0.1 0.2 10.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KNZ74757.1 - 0.037 13.9 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KNZ74757.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 KNZ74757.1 - 0.18 10.2 0.0 0.26 9.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein PIF1 PF05970.9 KNZ74758.1 - 2.7e-34 118.6 0.0 3.1e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Phage_GP20 PF06810.6 KNZ74760.1 - 0.023 14.1 1.1 0.026 13.9 0.8 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 NDUF_B6 PF09782.4 KNZ74760.1 - 0.058 13.2 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit YoqO PF14037.1 KNZ74761.1 - 8.3 6.5 9.0 0.89 9.6 0.4 2.7 2 1 0 2 2 2 0 YoqO-like protein F-box-like PF12937.2 KNZ74762.1 - 1.3e-05 24.8 0.3 1.3e-05 24.8 0.2 2.2 2 0 0 2 2 2 1 F-box-like DUF3535 PF12054.3 KNZ74764.1 - 1e-90 304.5 0.1 1.2e-89 300.9 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KNZ74764.1 - 2.5e-75 253.0 0.0 3.6e-75 252.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNZ74764.1 - 1.2e-12 47.5 0.0 2.6e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 KNZ74764.1 - 2e-12 46.0 7.2 0.45 10.7 0.0 8.8 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.1 KNZ74764.1 - 0.00069 20.0 15.6 13 6.4 0.1 8.0 8 0 0 8 8 8 1 HEAT-like repeat SOG2 PF10428.4 KNZ74765.1 - 1.9e-40 138.9 0.1 1.9e-40 138.9 0.1 2.8 2 1 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.2 KNZ74765.1 - 7.2e-18 63.8 2.9 3.4e-08 32.9 0.0 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) Cupin_8 PF13621.1 KNZ74765.1 - 5.7e-17 62.0 0.0 1.1e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain LRR_8 PF13855.1 KNZ74765.1 - 8.9e-15 54.2 6.6 8.7e-09 35.0 2.9 2.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KNZ74765.1 - 5.1e-08 31.8 2.8 1.3 9.3 0.2 5.9 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KNZ74765.1 - 4.1e-07 29.1 4.0 4.8 7.8 0.0 6.0 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 KNZ74765.1 - 0.0015 18.3 0.2 8.6 6.7 0.0 5.6 6 0 0 6 6 6 1 Leucine Rich repeat UCH_1 PF13423.1 KNZ74766.1 - 2.1e-45 155.4 0.1 3.6e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KNZ74766.1 - 3.8e-23 82.5 0.0 6.6e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 KNZ74766.1 - 9.1e-06 24.9 0.0 2.5e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TF_Zn_Ribbon PF08271.7 KNZ74766.1 - 0.14 11.5 1.3 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding dsDNA_bind PF01984.15 KNZ74767.1 - 2.1e-16 59.8 4.5 1.1e-12 47.8 0.2 2.0 2 0 0 2 2 2 2 Double-stranded DNA-binding domain MUG113 PF13455.1 KNZ74768.1 - 9.2e-17 61.2 0.1 1.2e-12 48.1 0.0 2.6 2 0 0 2 2 2 2 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KNZ74768.1 - 9.6e-11 41.9 0.0 2.2e-07 31.1 0.0 2.6 2 0 0 2 2 2 2 T5orf172 domain UDG PF03167.14 KNZ74770.1 - 1.2e-20 73.5 0.1 1.4e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Rota_NS35 PF02509.9 KNZ74770.1 - 0.018 13.7 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 FYVE PF01363.16 KNZ74771.1 - 8.4e-17 60.8 3.2 1.4e-16 60.0 2.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.3 KNZ74771.1 - 5.8e-06 25.7 0.7 1.3e-05 24.6 0.5 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE_2 PF02318.11 KNZ74771.1 - 0.0026 17.6 1.2 0.0076 16.1 0.9 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.16 KNZ74771.1 - 0.47 10.3 7.8 0.12 12.2 3.1 1.7 2 0 0 2 2 2 0 IBR domain zf-C2HC5 PF06221.8 KNZ74771.1 - 0.56 10.0 8.9 0.33 10.7 4.6 1.8 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type DZR PF12773.2 KNZ74771.1 - 3.3 7.6 5.9 2.5 7.9 2.3 2.0 2 0 0 2 2 2 0 Double zinc ribbon DUF4206 PF13901.1 KNZ74771.1 - 7.5 6.0 10.0 0.23 10.9 1.2 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4206) Cofilin_ADF PF00241.15 KNZ74772.1 - 7.7e-22 77.5 0.0 9.6e-11 41.6 0.0 2.5 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Lysine_decarbox PF03641.9 KNZ74773.1 - 3e-33 114.4 0.0 4.5e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase tRNA-synt_1b PF00579.20 KNZ74774.1 - 5.2e-23 81.6 0.0 1.2e-22 80.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-RING_4 PF14570.1 KNZ74775.1 - 7.3e-17 60.6 7.2 1.2e-16 60.0 5.0 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain CAF-1_p150 PF11600.3 KNZ74775.1 - 0.00013 21.3 40.8 0.00013 21.3 28.3 2.7 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal RRM_1 PF00076.17 KNZ74775.1 - 0.0058 16.2 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ74775.1 - 0.0072 16.1 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 KNZ74775.1 - 0.01 15.4 5.7 0.02 14.5 4.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 KNZ74775.1 - 0.018 14.7 2.6 0.047 13.4 1.8 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.1 KNZ74775.1 - 0.33 11.0 8.6 0.64 10.1 5.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 KNZ74775.1 - 0.36 10.5 3.3 0.74 9.5 2.3 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FAD-oxidase_C PF02913.14 KNZ74776.1 - 1.8e-54 184.6 0.0 2.5e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KNZ74776.1 - 4.8e-28 97.3 0.0 9.1e-28 96.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain MS_channel PF00924.13 KNZ74777.1 - 4.1e-17 62.2 1.0 7.5e-17 61.3 0.7 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KNZ74777.1 - 0.00011 21.1 0.2 0.00031 19.8 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KNZ74777.1 - 0.00078 19.1 0.1 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 KNZ74777.1 - 0.0022 18.0 0.0 0.0059 16.7 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KNZ74777.1 - 0.0057 15.9 0.2 0.018 14.3 0.1 1.9 1 0 0 1 1 1 1 EF hand HSA PF07529.8 KNZ74778.1 - 5.9e-14 51.6 0.6 5.9e-14 51.6 0.4 2.7 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.1 KNZ74778.1 - 5.2e-07 29.6 0.3 1.5e-06 28.1 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KNZ74778.1 - 0.00015 21.7 0.3 0.00056 19.9 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Cellulase PF00150.13 KNZ74779.1 - 2.4e-10 40.0 0.0 4.9e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pectate_lyase_3 PF12708.2 KNZ74781.1 - 1e-77 261.2 12.8 9.5e-69 231.9 6.1 2.5 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KNZ74781.1 - 0.0046 16.4 0.5 0.012 15.0 0.4 1.7 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase CDC45 PF02724.9 KNZ74782.1 - 8.2e-178 592.2 0.0 1e-177 592.0 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.8 KNZ74782.1 - 0.22 11.1 8.5 0.33 10.5 5.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Scramblase PF03803.10 KNZ74783.1 - 4e-43 147.0 0.0 3e-32 111.4 0.0 2.0 1 1 1 2 2 2 2 Scramblase GTP_EFTU PF00009.22 KNZ74784.1 - 2.3e-38 131.5 0.4 1.4e-37 128.9 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KNZ74784.1 - 3e-28 97.8 1.1 1.3e-27 95.8 0.8 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 KNZ74784.1 - 1.8e-07 31.1 0.3 3.9e-06 26.8 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 KNZ74784.1 - 1.9e-05 24.7 0.6 0.0099 15.9 0.0 3.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Miro PF08477.8 KNZ74784.1 - 0.00015 22.2 0.0 0.00031 21.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KNZ74784.1 - 0.0013 18.2 0.5 1.2 8.6 0.1 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation IF2_N PF04760.10 KNZ74784.1 - 0.0021 17.7 0.0 0.0081 15.7 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region SRPRB PF09439.5 KNZ74784.1 - 0.012 14.8 0.0 0.029 13.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MobB PF03205.9 KNZ74784.1 - 0.041 13.5 0.6 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CHORD PF04968.7 KNZ74785.1 - 3.4e-35 120.0 5.4 4e-23 81.4 0.4 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.11 KNZ74785.1 - 2.5e-16 59.9 0.3 4.9e-16 59.0 0.2 1.5 1 0 0 1 1 1 1 CS domain Mito_carr PF00153.22 KNZ74785.1 - 8.9e-10 38.1 0.2 0.00059 19.4 0.0 3.5 4 0 0 4 4 4 2 Mitochondrial carrier protein 2OG-FeII_Oxy_2 PF13532.1 KNZ74786.1 - 4.7e-12 46.1 0.5 7.9e-12 45.4 0.4 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 KNZ74788.1 - 1.3e-08 34.3 0.6 3.4e-08 32.9 0.4 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74788.1 - 0.0002 20.5 0.2 0.00093 18.3 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Herpes_Helicase PF02689.9 KNZ74789.1 - 7.3e-05 20.7 0.0 7.4e-05 20.7 0.0 1.0 1 0 0 1 1 1 1 Helicase DUF11 PF01345.13 KNZ74789.1 - 0.14 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF11 Exo_endo_phos PF03372.18 KNZ74791.1 - 0.00032 20.7 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family OmpH PF03938.9 KNZ74791.1 - 0.7 9.8 6.4 1.7 8.5 3.7 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) HsbA PF12296.3 KNZ74792.1 - 2.8e-06 27.1 4.3 0.00051 19.9 0.7 2.4 2 1 1 3 3 3 2 Hydrophobic surface binding protein A Pex2_Pex12 PF04757.9 KNZ74793.1 - 1.1e-35 123.1 6.7 1.5e-35 122.6 4.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.1 KNZ74793.1 - 0.00072 19.2 0.8 0.003 17.2 0.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KNZ74793.1 - 0.011 15.5 1.8 0.16 11.8 0.3 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 KNZ74793.1 - 0.051 13.5 0.9 0.051 13.5 0.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KNZ74793.1 - 0.064 13.1 0.9 0.18 11.7 0.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KNZ74793.1 - 0.068 13.2 0.6 0.25 11.4 0.4 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger FYVE PF01363.16 KNZ74793.1 - 0.17 11.8 2.8 0.16 11.8 0.6 1.8 2 0 0 2 2 2 0 FYVE zinc finger IBN_N PF03810.14 KNZ74794.1 - 0.0003 20.6 1.9 0.0049 16.7 0.1 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KNZ74794.1 - 0.0089 15.9 0.0 0.036 13.9 0.0 2.1 2 0 0 2 2 2 1 Exportin 1-like protein Slx4 PF09494.5 KNZ74795.1 - 0.0018 17.9 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Mur_ligase_M PF08245.7 KNZ74796.1 - 2.1e-07 31.1 0.6 9.5e-05 22.5 0.6 3.4 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.16 KNZ74796.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain BRCT PF00533.21 KNZ74797.1 - 2e-07 31.0 0.0 2.6e-06 27.4 0.0 2.4 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Vps52 PF04129.7 KNZ74799.1 - 9e-57 192.7 1.1 2.8e-42 144.9 0.0 3.0 2 1 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.4 KNZ74799.1 - 0.00011 20.5 0.2 0.002 16.3 0.0 2.3 1 1 1 2 2 2 1 Exocyst complex component Sec3 GP41 PF00517.12 KNZ74799.1 - 0.067 12.7 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Retroviral envelope protein COG2 PF06148.6 KNZ74799.1 - 0.099 12.5 1.8 0.16 11.8 0.3 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin PF00804.20 KNZ74799.1 - 0.41 10.8 4.6 0.16 12.1 0.3 2.5 3 1 0 3 3 3 0 Syntaxin JAB PF01398.16 KNZ74801.1 - 2.6e-34 117.3 0.2 4.5e-34 116.6 0.2 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KNZ74801.1 - 2.2e-28 98.6 2.7 5.6e-28 97.3 1.9 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KNZ74801.1 - 8.9e-08 31.6 0.0 1.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 KNZ74801.1 - 0.061 12.8 0.6 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Ribosomal_S18 PF01084.15 KNZ74802.1 - 2.5e-15 56.0 0.1 4.5e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Pkinase PF00069.20 KNZ74803.1 - 7.7e-62 208.7 0.0 1.2e-40 139.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ74803.1 - 4.7e-27 94.6 0.0 2e-22 79.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KNZ74803.1 - 2e-13 50.3 0.1 4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 KNZ74803.1 - 1.2e-06 27.7 0.0 0.00023 20.2 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KNZ74803.1 - 0.0011 18.6 1.0 0.0039 16.9 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KNZ74803.1 - 0.016 14.3 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KNZ74803.1 - 0.035 12.9 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3432 PF11914.3 KNZ74804.1 - 0.17 11.9 3.6 0.17 11.9 1.5 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF3432) THOC7 PF05615.8 KNZ74805.1 - 1.4e-25 90.2 5.6 2.9e-25 89.1 3.9 1.5 1 0 0 1 1 1 1 Tho complex subunit 7 DUF842 PF05811.8 KNZ74805.1 - 0.013 14.9 0.3 0.026 13.9 0.2 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) AAA_13 PF13166.1 KNZ74805.1 - 0.058 11.8 3.8 0.085 11.3 2.6 1.2 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 KNZ74805.1 - 0.13 12.0 11.5 0.57 10.0 6.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3505 PF12013.3 KNZ74805.1 - 0.16 12.1 2.7 0.45 10.7 1.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3505) Cep57_MT_bd PF06657.8 KNZ74805.1 - 0.6 10.0 6.0 3.7 7.5 1.1 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4140 PF13600.1 KNZ74805.1 - 0.72 10.3 5.1 7.5 7.0 1.7 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cortex-I_coil PF09304.5 KNZ74805.1 - 0.78 9.8 11.0 1.5 8.9 0.3 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil Mnd1 PF03962.10 KNZ74805.1 - 3.7 7.1 8.5 10 5.7 5.9 1.8 1 1 0 1 1 1 0 Mnd1 family DUF4337 PF14235.1 KNZ74805.1 - 3.8 7.3 5.7 2.7 7.7 2.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Lactamase_B_2 PF12706.2 KNZ74806.1 - 2.8e-23 82.4 0.0 3.8e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KNZ74806.1 - 0.00015 21.4 5.0 0.001 18.7 3.4 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.10 KNZ74806.1 - 0.089 11.6 0.1 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II RhoGEF PF00621.15 KNZ74808.1 - 8.7e-36 123.4 0.1 3.8e-35 121.3 0.0 2.1 2 0 0 2 2 2 1 RhoGEF domain IFP_35_N PF07334.8 KNZ74808.1 - 3.8 7.5 7.4 3 7.8 0.3 2.6 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus RhoGEF PF00621.15 KNZ74809.1 - 3.3e-19 69.4 3.8 2.1e-17 63.5 2.6 2.9 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.24 KNZ74809.1 - 0.0051 17.0 0.0 0.024 14.8 0.0 2.1 2 0 0 2 2 2 1 PH domain LRR_6 PF13516.1 KNZ74810.1 - 1.1e-12 46.6 10.7 0.13 12.4 0.0 8.9 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.2 KNZ74810.1 - 2.1e-12 46.3 0.9 0.0016 17.9 0.0 7.2 7 2 0 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KNZ74810.1 - 7.3e-11 40.5 12.6 2.3 8.5 0.0 8.1 7 2 0 7 7 7 5 Leucine Rich Repeat LRR_8 PF13855.1 KNZ74810.1 - 2.5e-05 23.9 6.5 0.085 12.6 0.0 5.3 4 1 2 6 6 6 2 Leucine rich repeat LRR_7 PF13504.1 KNZ74810.1 - 0.0003 20.4 20.0 5.4 7.6 0.0 8.3 9 0 0 9 9 9 2 Leucine rich repeat Amidohydro_4 PF13147.1 KNZ74812.1 - 2.1e-17 64.0 0.5 2.3e-16 60.6 0.3 2.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KNZ74812.1 - 3.3e-14 52.4 0.5 5.2e-10 38.9 0.1 3.5 4 0 0 4 4 4 2 Amidohydrolase Amidohydro_3 PF07969.6 KNZ74812.1 - 1e-07 31.5 0.6 3.3e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.15 KNZ74812.1 - 4.1e-06 26.6 0.1 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Myb_DNA-binding PF00249.26 KNZ74813.1 - 1.1e-16 60.6 5.7 1.7e-07 31.1 0.0 4.4 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KNZ74813.1 - 7.1e-14 51.6 1.9 1.7e-09 37.6 0.0 3.8 2 1 2 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KNZ74813.1 - 0.02 15.0 1.9 0.069 13.2 0.1 2.8 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain DUF676 PF05057.9 KNZ74814.1 - 5.3e-05 22.6 0.0 0.00016 21.0 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KNZ74814.1 - 7.5e-05 22.5 0.0 0.00015 21.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ74814.1 - 0.00016 21.6 0.3 0.00038 20.4 0.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KNZ74814.1 - 0.0047 16.5 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 KNZ74814.1 - 0.0072 15.9 0.0 0.02 14.5 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 KNZ74814.1 - 0.011 14.8 0.0 0.86 8.6 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.7 KNZ74814.1 - 0.066 12.5 0.0 0.39 9.9 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 KNZ74814.1 - 0.071 12.6 0.6 0.24 10.9 0.4 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DctQ PF04290.7 KNZ74814.1 - 0.11 12.2 0.7 0.61 9.8 0.1 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Acetyltransf_1 PF00583.19 KNZ74815.1 - 8.1e-14 51.4 0.0 1.1e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KNZ74815.1 - 0.00014 21.9 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KNZ74815.1 - 0.00016 21.3 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KNZ74815.1 - 0.0017 18.4 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KNZ74815.1 - 0.0026 17.6 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KNZ74815.1 - 0.058 13.5 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PAF-AH_p_II PF03403.8 KNZ74816.1 - 2.6e-32 111.5 0.0 1.5e-31 109.0 0.0 2.0 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KNZ74816.1 - 1.2e-09 38.0 0.0 2.3e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ74816.1 - 2.2e-07 30.9 0.0 4e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KNZ74816.1 - 6e-05 22.0 0.0 0.0047 15.8 0.0 2.4 3 0 0 3 3 3 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KNZ74816.1 - 0.0025 16.6 0.0 0.012 14.4 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 KNZ74816.1 - 0.0073 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 KNZ74816.1 - 0.07 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family F-box-like PF12937.2 KNZ74818.1 - 6.7e-11 41.7 0.9 6.7e-11 41.7 0.6 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KNZ74818.1 - 7.9e-11 41.3 6.0 0.28 10.8 0.0 6.5 5 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNZ74818.1 - 0.00026 20.6 15.8 1.6 8.5 0.1 5.9 3 2 2 6 6 6 3 Leucine rich repeat F-box PF00646.28 KNZ74818.1 - 0.0023 17.5 0.4 0.0023 17.5 0.3 3.8 3 0 0 3 3 3 1 F-box domain Ste50p-SAM PF09235.5 KNZ74818.1 - 0.098 12.6 5.9 9.9 6.2 0.1 3.7 3 1 0 3 3 3 0 Ste50p, sterile alpha motif NOA36 PF06524.7 KNZ74818.1 - 2 7.6 2.7 8.5 5.5 0.0 2.1 2 0 0 2 2 2 0 NOA36 protein DUF4050 PF13259.1 KNZ74819.1 - 0.0049 16.7 0.6 0.049 13.5 0.4 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) LSM PF01423.17 KNZ74820.1 - 1.1e-17 63.3 0.6 1.9e-17 62.5 0.4 1.3 1 0 0 1 1 1 1 LSM domain zf-U1 PF06220.7 KNZ74821.1 - 1.7e-20 72.2 4.3 2.4e-20 71.7 3.0 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 KNZ74821.1 - 0.025 14.7 2.4 0.046 13.8 1.7 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF202 PF02656.10 KNZ74822.1 - 4.8e-14 52.3 2.1 4.8e-14 52.3 1.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3040 PF11239.3 KNZ74822.1 - 2.4 8.2 5.2 4.7 7.3 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) DUF2530 PF10745.4 KNZ74822.1 - 3.9 7.5 5.9 8 6.5 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) Myb_DNA-bind_6 PF13921.1 KNZ74823.1 - 0.031 14.3 0.2 0.097 12.7 0.0 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain BRO1 PF03097.13 KNZ74824.1 - 9.3e-117 389.9 0.1 1.4e-116 389.3 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KNZ74824.1 - 1.5e-48 165.3 0.1 3.6e-48 164.0 0.1 1.7 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF543 PF04418.7 KNZ74825.1 - 4e-21 74.7 0.1 4.5e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) AAA PF00004.24 KNZ74826.1 - 1.6e-13 51.0 0.0 4.6e-13 49.5 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF1904 PF08921.6 KNZ74826.1 - 0.043 13.8 0.3 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) tRNA-synt_1c PF00749.16 KNZ74827.1 - 3.7e-104 347.7 0.0 5.1e-104 347.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KNZ74827.1 - 7.6e-29 100.5 0.0 2.5e-28 98.8 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 KNZ74827.1 - 7.9e-28 97.0 0.0 1.2e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 KNZ74827.1 - 7.7e-08 32.9 4.3 7.7e-08 32.9 3.0 2.4 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 INTS5_C PF14838.1 KNZ74827.1 - 0.18 10.0 0.0 0.29 9.3 0.0 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus Tubulin PF00091.20 KNZ74828.1 - 9.9e-67 224.9 0.0 1.4e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KNZ74828.1 - 3.4e-48 162.8 0.0 5.4e-48 162.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KNZ74828.1 - 0.0021 17.5 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Abhydrolase_3 PF07859.8 KNZ74829.1 - 1.3e-37 129.4 0.0 7.1e-30 104.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KNZ74829.1 - 8.2e-11 41.1 0.0 3.3e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KNZ74829.1 - 0.0052 16.5 0.0 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2789 PF10982.3 KNZ74829.1 - 0.15 12.1 0.1 19 5.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2789) CPSF100_C PF13299.1 KNZ74830.1 - 8.7e-28 97.5 4.0 4.8e-27 95.1 0.0 3.1 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KNZ74830.1 - 4.8e-23 81.4 0.0 1e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.2 KNZ74830.1 - 0.003 17.1 0.0 0.0065 16.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CDC45 PF02724.9 KNZ74830.1 - 0.33 8.9 7.6 0.48 8.3 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KNZ74830.1 - 3.8 5.3 12.2 6.1 4.6 8.5 1.3 1 0 0 1 1 1 0 Nop14-like family Nucleo_P87 PF07267.6 KNZ74830.1 - 3.8 6.0 7.3 6 5.4 5.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Tubulin PF00091.20 KNZ74831.1 - 9.3e-69 231.5 0.0 1.3e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KNZ74831.1 - 2.9e-45 153.3 0.0 4.3e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KNZ74831.1 - 0.0009 18.7 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 KNZ74831.1 - 0.0024 17.4 0.0 2.6 7.6 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) HAD_2 PF13419.1 KNZ74832.1 - 1.4e-15 57.9 0.0 1.9e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KNZ74832.1 - 1e-10 41.1 0.0 2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KNZ74832.1 - 2.7e-09 37.7 0.2 4e-08 33.9 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KNZ74832.1 - 0.0026 17.9 0.0 0.0043 17.2 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sec15 PF04091.7 KNZ74833.1 - 2.5e-66 224.1 0.0 5e-66 223.1 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG5 PF10392.4 KNZ74833.1 - 6.1e-08 32.7 0.4 6.1e-08 32.7 0.3 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.6 KNZ74833.1 - 4.5e-06 26.3 0.7 3.4e-05 23.5 0.0 3.0 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.1 KNZ74833.1 - 5e-06 26.3 0.3 1.5e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec5 Sec8_exocyst PF04048.9 KNZ74833.1 - 0.00039 20.0 1.7 0.0014 18.2 0.2 2.6 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG2 PF06148.6 KNZ74833.1 - 0.017 14.9 0.7 0.017 14.9 0.5 2.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Arf PF00025.16 KNZ74834.1 - 6.1e-79 263.2 0.1 7e-79 263.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KNZ74834.1 - 2.5e-14 52.8 0.0 3.1e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KNZ74834.1 - 9e-13 47.9 0.0 9.8e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KNZ74834.1 - 2.9e-12 45.9 1.2 3.8e-09 35.7 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KNZ74834.1 - 4.3e-11 42.4 0.0 5.1e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KNZ74834.1 - 2.8e-09 37.4 0.0 3.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KNZ74834.1 - 6.1e-06 26.1 0.0 8.1e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KNZ74834.1 - 0.0069 15.4 0.4 0.013 14.5 0.3 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KNZ74834.1 - 0.0082 15.6 0.1 0.071 12.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KNZ74834.1 - 0.05 13.4 0.2 0.14 12.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KNZ74834.1 - 0.16 11.4 0.3 2.4 7.6 0.1 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DSPc PF00782.15 KNZ74835.1 - 1.4e-29 102.3 0.0 1.6e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KNZ74835.1 - 2.6e-06 26.9 0.0 3.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Apt1 PF10351.4 KNZ74836.1 - 8.1 5.1 7.9 9.1 5.0 5.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3245 PF11595.3 KNZ74837.1 - 1.8e-05 25.0 0.0 1.8e-05 25.0 0.0 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF3245) DUF2702 PF10863.3 KNZ74837.1 - 0.0086 15.7 0.2 0.0086 15.7 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2702) PBP1_TM PF14812.1 KNZ74837.1 - 1.3 9.4 7.4 0.88 9.9 0.4 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SIP1 PF04938.7 KNZ74838.1 - 1.1e-17 64.2 1.4 7e-16 58.2 1.0 2.2 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Utp12 PF04003.7 KNZ74838.1 - 0.033 14.0 0.2 0.079 12.8 0.1 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family QRPTase_C PF01729.14 KNZ74839.1 - 4.5e-38 130.4 0.0 9.1e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KNZ74839.1 - 1.2e-21 76.3 0.0 3.1e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain GPI-anchored PF10342.4 KNZ74839.1 - 2e-11 44.2 0.3 2e-11 44.2 0.2 2.4 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Amidohydro_2 PF04909.9 KNZ74840.1 - 2.4e-31 109.3 0.1 3.3e-31 108.8 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Asparaginase PF00710.15 KNZ74840.1 - 0.019 13.8 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Asparaginase TatD_DNase PF01026.16 KNZ74840.1 - 0.045 12.9 0.0 0.088 11.9 0.0 1.4 1 0 0 1 1 1 0 TatD related DNase Phage_GP20 PF06810.6 KNZ74841.1 - 0.0037 16.7 4.6 0.0037 16.7 3.2 2.0 1 1 1 2 2 2 1 Phage minor structural protein GP20 AAA_13 PF13166.1 KNZ74841.1 - 0.02 13.3 8.0 0.025 13.0 5.5 1.0 1 0 0 1 1 1 0 AAA domain Tweety PF04906.8 KNZ74841.1 - 0.027 12.9 2.4 0.037 12.4 1.7 1.2 1 0 0 1 1 1 0 Tweety Fib_alpha PF08702.5 KNZ74841.1 - 0.1 12.7 5.3 0.12 12.4 3.1 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Cep57_CLD_2 PF14197.1 KNZ74841.1 - 0.11 12.4 5.8 0.15 11.9 3.4 1.8 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 KIP1 PF07765.7 KNZ74841.1 - 0.11 12.3 0.4 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 KIP1-like protein DUF3584 PF12128.3 KNZ74841.1 - 0.21 8.9 10.4 0.26 8.5 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin_2 PF14523.1 KNZ74841.1 - 0.22 11.5 8.0 0.1 12.6 2.7 2.1 2 0 0 2 2 2 0 Syntaxin-like protein P4Ha_N PF08336.6 KNZ74841.1 - 0.23 11.2 4.6 0.37 10.6 2.2 1.9 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fucose_iso_N2 PF07882.7 KNZ74841.1 - 0.28 10.8 2.0 0.41 10.2 1.4 1.3 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Exonuc_VII_L PF02601.10 KNZ74841.1 - 0.35 10.0 4.5 0.35 10.0 3.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2458 PF10454.4 KNZ74841.1 - 0.38 10.6 5.9 0.76 9.6 4.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) GHL5 PF14872.1 KNZ74841.1 - 0.41 8.3 2.1 0.49 8.1 1.5 1.1 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 OmpH PF03938.9 KNZ74841.1 - 0.58 10.0 9.0 1 9.2 6.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CorA PF01544.13 KNZ74841.1 - 0.97 8.4 5.8 1.2 8.0 4.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein YlqD PF11068.3 KNZ74841.1 - 1.1 9.2 11.4 0.31 11.0 5.1 1.9 1 1 1 2 2 2 0 YlqD protein TMCO5 PF14992.1 KNZ74841.1 - 1.4 8.0 11.5 7 5.7 8.3 1.8 1 1 1 2 2 2 0 TMCO5 family Mnd1 PF03962.10 KNZ74841.1 - 1.8 8.1 10.3 3.8 7.1 7.1 1.6 1 1 0 1 1 1 0 Mnd1 family Dor1 PF04124.7 KNZ74841.1 - 2.3 6.5 9.3 2.5 6.4 5.6 1.6 1 1 1 2 2 2 0 Dor1-like family Syntaxin-6_N PF09177.6 KNZ74841.1 - 2.5 8.5 10.1 1.2e+02 3.1 7.0 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TMPIT PF07851.8 KNZ74841.1 - 2.6 7.0 6.1 1.8 7.5 3.2 1.4 1 1 0 1 1 1 0 TMPIT-like protein Prefoldin PF02996.12 KNZ74841.1 - 4 7.1 9.2 13 5.4 0.2 2.7 1 1 1 3 3 3 0 Prefoldin subunit EphA2_TM PF14575.1 KNZ74842.1 - 0.071 13.5 0.1 0.11 12.9 0.1 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HAMP PF00672.20 KNZ74842.1 - 0.081 13.1 0.6 1.6 8.9 0.6 2.1 2 0 0 2 2 2 0 HAMP domain GRA6 PF05084.8 KNZ74842.1 - 0.13 11.7 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) PIF1 PF05970.9 KNZ74843.1 - 9.5e-107 357.0 0.0 1.1e-106 356.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ74843.1 - 0.00081 19.0 0.0 0.0016 18.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KNZ74843.1 - 0.049 13.1 0.2 0.1 12.1 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Helitron_like_N PF14214.1 KNZ74844.1 - 3.5e-36 124.6 0.1 1.4e-35 122.7 0.0 1.8 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 KNZ74844.1 - 4.1e-08 32.3 0.1 7.9e-08 31.3 0.1 1.4 1 1 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) DUF3296 PF11726.3 KNZ74844.1 - 0.0061 16.1 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) SUI1 PF01253.17 KNZ74844.1 - 0.15 11.9 0.8 0.4 10.5 0.0 2.1 3 0 0 3 3 3 0 Translation initiation factor SUI1 Asp_protease_2 PF13650.1 KNZ74847.1 - 1.1e-06 29.0 0.0 3.3e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.5 KNZ74847.1 - 0.02 14.4 0.1 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease MSA-2c PF12238.3 KNZ74848.1 - 0.33 10.5 2.6 0.38 10.3 1.8 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF2360 PF10152.4 KNZ74848.1 - 1.2 9.4 3.7 1.3 9.2 2.6 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) LEA_3 PF03242.8 KNZ74849.1 - 0.12 12.6 0.2 15 5.8 0.3 2.2 2 0 0 2 2 2 0 Late embryogenesis abundant protein Tom37 PF10568.4 KNZ74850.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein Asp_protease_2 PF13650.1 KNZ74851.1 - 0.0041 17.5 0.0 0.024 15.1 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease FNIP_N PF14636.1 KNZ74852.1 - 0.064 13.7 0.8 0.12 12.8 0.5 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus DUF2373 PF10180.4 KNZ74853.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Papilloma_E5A PF05776.7 KNZ74854.1 - 3.3 7.9 6.0 1.5 9.0 1.9 1.9 2 0 0 2 2 2 0 Papillomavirus E5A protein CoA_binding_2 PF13380.1 KNZ74857.1 - 6.9e-17 61.6 0.0 7.9e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding_2 PF13380.1 KNZ74858.1 - 2e-29 102.0 0.0 2.4e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain PALP PF00291.20 KNZ74859.1 - 2.9e-39 135.1 0.1 1.5e-38 132.7 0.1 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PIG-U PF06728.8 KNZ74860.1 - 6.5e-65 219.4 27.6 7.4e-65 219.2 19.2 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U BRO1 PF03097.13 KNZ74861.1 - 3.5e-16 58.9 0.0 4.8e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain NAD_kinase PF01513.16 KNZ74863.1 - 6.9e-59 198.9 0.0 9.2e-59 198.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase MRFAP1 PF15155.1 KNZ74864.1 - 0.067 13.5 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 MORF4 family-associated protein1 DUF3446 PF11928.3 KNZ74864.1 - 0.069 13.3 1.3 0.14 12.4 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3446) XPG_I_2 PF12813.2 KNZ74865.1 - 2.3e-07 30.5 0.0 7.3e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 XPG domain containing XPG_N PF00752.12 KNZ74865.1 - 0.024 14.9 0.0 0.071 13.3 0.0 1.8 1 0 0 1 1 1 0 XPG N-terminal domain GSK-3_bind PF05350.7 KNZ74865.1 - 0.088 12.2 0.7 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Glycogen synthase kinase-3 binding DPBB_1 PF03330.13 KNZ74866.1 - 0.00023 21.0 0.2 0.00062 19.7 0.0 1.8 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KNZ74866.1 - 0.00085 18.9 0.1 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Barwin family zinc_ribbon_2 PF13240.1 KNZ74866.1 - 0.013 14.9 0.4 0.17 11.4 0.1 2.5 2 1 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KNZ74866.1 - 0.099 11.8 2.2 7.2 5.9 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Cornichon PF03311.9 KNZ74867.1 - 3.5e-44 150.0 9.0 4.2e-44 149.7 6.3 1.1 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.6 KNZ74867.1 - 0.057 13.0 1.9 0.066 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) Cornichon PF03311.9 KNZ74868.1 - 1.1e-44 151.7 3.8 1.2e-44 151.5 2.6 1.0 1 0 0 1 1 1 1 Cornichon protein SopA_C PF13979.1 KNZ74869.1 - 0.0096 15.5 0.1 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 SopA-like catalytic domain AMP-binding PF00501.23 KNZ74870.1 - 1.6e-67 227.7 0.0 4.9e-66 222.8 0.0 2.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KNZ74870.1 - 2.8e-08 34.5 1.0 5.4e-08 33.6 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4482 PF14818.1 KNZ74871.1 - 0.028 15.0 1.0 0.043 14.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) RBFA PF02033.13 KNZ74871.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.6 2 0 0 2 2 2 0 Ribosome-binding factor A Tox-REase-9 PF15650.1 KNZ74871.1 - 0.14 12.3 0.1 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 RRM_1 PF00076.17 KNZ74872.1 - 6.1e-06 25.7 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ74872.1 - 0.0037 17.2 0.0 0.0079 16.1 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Hydrophobin PF01185.13 KNZ74873.1 - 1.7e-13 50.8 13.2 2.1e-13 50.5 9.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 KNZ74874.1 - 2.1e-11 44.1 14.8 2.4e-11 43.8 10.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DAO PF01266.19 KNZ74875.1 - 7.2e-45 153.4 0.0 8.5e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KNZ74875.1 - 8.2e-06 25.7 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KNZ74875.1 - 1.2e-05 25.4 0.0 0.00017 21.6 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KNZ74875.1 - 4.5e-05 23.4 0.0 0.37 10.6 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KNZ74875.1 - 0.00032 21.0 0.0 0.0086 16.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KNZ74875.1 - 0.00074 19.6 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.19 KNZ74875.1 - 0.0013 17.9 0.0 0.22 10.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.17 KNZ74875.1 - 0.0016 17.3 0.2 0.5 9.1 0.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KNZ74875.1 - 0.01 14.7 0.1 1.8 7.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 KNZ74875.1 - 0.023 14.4 0.0 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 KNZ74875.1 - 0.026 13.6 0.0 0.049 12.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KNZ74875.1 - 0.04 12.3 0.0 4.5 5.6 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.1 KNZ74875.1 - 0.045 13.9 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 KNZ74875.1 - 0.081 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 KNZ74875.1 - 0.097 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KNZ74875.1 - 0.099 11.5 0.1 5.8 5.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Glyco_transf_49 PF13896.1 KNZ74876.1 - 6.7e-37 127.2 0.1 7.4e-30 104.1 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_4 PF13704.1 KNZ74876.1 - 0.077 13.3 0.4 0.19 12.0 0.1 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 Ank_2 PF12796.2 KNZ74877.1 - 0.00035 20.8 0.0 0.0098 16.2 0.0 2.9 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNZ74877.1 - 0.00089 19.7 0.2 4.4 7.9 0.0 4.2 3 2 0 3 3 3 2 Ankyrin repeats (many copies) SAP PF02037.22 KNZ74877.1 - 0.0037 16.7 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 SAP domain Ank_3 PF13606.1 KNZ74877.1 - 0.02 15.0 0.0 17 6.0 0.0 4.7 5 0 0 5 5 5 0 Ankyrin repeat SWIB PF02201.13 KNZ74879.1 - 1.6e-25 88.5 0.0 2.7e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain TATR PF03430.8 KNZ74879.1 - 1.3 7.5 4.8 1.5 7.3 3.3 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator PBP1_TM PF14812.1 KNZ74879.1 - 4.8 7.5 22.3 2.5 8.4 5.5 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sel1 PF08238.7 KNZ74880.1 - 1.7e-27 95.2 35.6 4.7e-06 27.0 0.0 10.7 11 1 0 11 11 11 6 Sel1 repeat TPR_11 PF13414.1 KNZ74880.1 - 1.1e-06 28.1 3.9 0.0016 18.0 0.1 4.4 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.1 KNZ74880.1 - 0.013 16.1 0.3 0.013 16.1 0.2 5.0 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ74880.1 - 0.043 13.7 0.3 0.043 13.7 0.2 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ74880.1 - 0.044 13.7 0.4 0.044 13.7 0.2 4.2 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ74880.1 - 0.15 12.0 2.3 0.91 9.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ74880.1 - 0.22 12.2 5.6 0.26 12.0 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ74880.1 - 3 8.5 13.0 21 5.8 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat PPTA PF01239.17 KNZ74881.1 - 8.9e-07 28.0 13.6 0.00072 18.7 0.7 3.8 3 0 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat RNase_T PF00929.19 KNZ74882.1 - 4e-25 88.9 0.0 4.8e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Nucleoside_tran PF01733.13 KNZ74883.1 - 0.076 12.1 3.7 0.097 11.8 0.7 2.1 1 1 0 2 2 2 0 Nucleoside transporter CPSase_L_D2 PF02786.12 KNZ74884.1 - 7.2e-108 358.7 0.0 2.6e-83 278.4 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KNZ74884.1 - 6.2e-42 142.2 0.3 1.2e-41 141.3 0.2 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KNZ74884.1 - 1.1e-36 126.3 0.2 1e-18 67.7 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 KNZ74884.1 - 5.5e-35 119.7 0.0 1.1e-17 64.1 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KNZ74884.1 - 4.2e-21 75.0 0.0 4.2e-08 32.3 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KNZ74884.1 - 5.7e-17 61.6 0.0 2.5e-07 30.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KNZ74884.1 - 2.9e-13 49.6 0.0 2.3e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KNZ74884.1 - 6.5e-08 32.2 0.0 0.0032 16.9 0.0 2.7 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KNZ74884.1 - 2e-05 24.5 0.0 0.003 17.4 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.1 KNZ74884.1 - 2.2e-05 23.7 0.1 0.03 13.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_M17_N PF02789.12 KNZ74884.1 - 0.095 12.4 0.4 0.61 9.8 0.0 2.5 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain 2-oxoacid_dh PF00198.18 KNZ74885.1 - 7.6e-82 274.0 0.1 9.7e-82 273.6 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KNZ74885.1 - 1.2e-15 56.8 2.5 2.4e-15 55.9 1.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 KNZ74885.1 - 3e-05 23.3 3.3 0.00012 21.4 1.0 2.0 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 KNZ74885.1 - 0.0014 18.2 2.3 0.0096 15.5 1.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.1 KNZ74885.1 - 0.029 14.0 0.5 0.15 11.7 0.4 2.2 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 KNZ74885.1 - 0.053 13.2 2.6 0.061 13.0 0.3 2.0 1 1 1 2 2 2 0 Glycine cleavage H-protein HlyD_3 PF13437.1 KNZ74885.1 - 0.053 13.8 2.5 2.6 8.4 0.6 2.5 1 1 1 2 2 2 0 HlyD family secretion protein Lyase_aromatic PF00221.14 KNZ74886.1 - 1.9e-161 537.7 0.6 2.6e-161 537.2 0.4 1.2 1 0 0 1 1 1 1 Aromatic amino acid lyase Fcf1 PF04900.7 KNZ74887.1 - 2.1e-39 133.6 0.9 2.1e-39 133.6 0.6 1.6 2 0 0 2 2 2 1 Fcf1 DUF1917 PF08939.5 KNZ74888.1 - 2.3e-27 96.3 0.2 2.3e-27 96.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1917) UPF0029 PF01205.14 KNZ74890.1 - 5.5e-21 74.3 0.0 9.2e-21 73.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Rer1 PF03248.8 KNZ74891.1 - 9.7e-73 243.4 2.8 1.1e-72 243.3 1.9 1.0 1 0 0 1 1 1 1 Rer1 family AAA_17 PF13207.1 KNZ74892.1 - 3.3e-06 27.8 0.0 5.4e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Torsin PF06309.6 KNZ74892.1 - 0.004 17.0 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_16 PF13191.1 KNZ74892.1 - 0.0049 16.8 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.9 KNZ74892.1 - 0.0056 15.7 0.0 0.0056 15.7 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_14 PF13173.1 KNZ74892.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KNZ74892.1 - 0.016 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KNZ74892.1 - 0.018 15.3 0.0 0.049 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KNZ74892.1 - 0.052 13.2 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 KNZ74892.1 - 0.07 12.8 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KNZ74892.1 - 0.096 12.5 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KNZ74892.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.19 KNZ74893.1 - 3.2e-08 33.4 0.0 5.5e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KNZ74893.1 - 2.3e-05 24.0 0.0 4.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KNZ74893.1 - 0.00034 20.8 0.0 0.00044 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KNZ74893.1 - 0.00047 20.2 0.0 0.00093 19.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KNZ74893.1 - 0.00062 19.7 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KNZ74893.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNZ74893.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KNZ74893.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Cyclin_N PF00134.18 KNZ74894.1 - 8.1e-10 38.3 0.0 1.1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KNZ74894.1 - 2.5e-07 31.1 0.1 8.3e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Cyclin zf-CCCH_2 PF14608.1 KNZ74895.1 - 3.6e-11 42.6 27.8 0.00012 21.8 2.2 4.3 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type AAA_16 PF13191.1 KNZ74896.1 - 7.7e-05 22.7 0.9 0.0011 19.0 0.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KNZ74896.1 - 0.023 14.0 0.0 0.067 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KNZ74896.1 - 0.12 11.8 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF221 PF02714.10 KNZ74897.1 - 5e-64 216.2 10.1 5e-64 216.2 7.0 2.8 3 1 1 4 4 4 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 KNZ74897.1 - 3.2e-35 121.0 0.2 3.2e-35 121.0 0.1 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KNZ74897.1 - 3.9e-12 46.5 0.0 9.8e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Tim17 PF02466.14 KNZ74898.1 - 2.6e-32 111.5 11.0 3.7e-30 104.6 7.6 2.1 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bcl-2 PF00452.14 KNZ74898.1 - 0.036 14.1 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family Arrestin_C PF02752.17 KNZ74899.1 - 1.4e-14 54.3 0.0 7.8e-14 51.9 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KNZ74899.1 - 7.7e-12 45.2 0.0 7.7e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KNZ74899.1 - 0.06 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Arrestin_N terminal like Cupredoxin_1 PF13473.1 KNZ74900.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Cupredoxin-like domain F-box-like PF12937.2 KNZ74901.1 - 0.031 13.9 0.0 0.089 12.5 0.0 1.9 1 0 0 1 1 1 0 F-box-like Amidohydro_1 PF01979.15 KNZ74902.1 - 2.4e-20 73.4 0.0 8.3e-20 71.7 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KNZ74902.1 - 6.1e-19 69.1 0.0 1.1e-18 68.2 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KNZ74902.1 - 5.6e-09 35.7 0.0 9.5e-08 31.6 0.0 2.1 1 1 0 2 2 2 1 Amidohydrolase family MFS_1 PF07690.11 KNZ74904.1 - 1.1e-36 126.2 32.4 1.5e-36 125.8 22.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_U4 PF03419.8 KNZ74904.1 - 0.29 10.1 6.8 0.67 8.9 4.7 1.6 1 0 0 1 1 1 0 Sporulation factor SpoIIGA MFS_1 PF07690.11 KNZ74905.1 - 1.5e-37 129.1 58.9 2.6e-34 118.5 24.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily P5-ATPase PF12409.3 KNZ74905.1 - 0.19 11.6 2.6 5.1 6.9 0.5 2.9 2 0 0 2 2 2 0 P5-type ATPase cation transporter CTP_transf_2 PF01467.21 KNZ74906.1 - 5e-26 91.6 0.0 6.2e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase DNA_pol_B_thumb PF14791.1 KNZ74907.1 - 1.3e-20 72.7 0.0 3e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 KNZ74907.1 - 3.1e-16 59.4 0.0 7.8e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 KNZ74907.1 - 7.7e-08 31.7 0.0 1.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 KNZ74907.1 - 0.0055 16.8 0.0 0.11 12.7 0.0 2.6 2 1 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 KNZ74907.1 - 0.011 15.8 0.0 0.066 13.3 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 KNZ74907.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Cdd1 PF11731.3 KNZ74907.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus Acyl-CoA_dh_1 PF00441.19 KNZ74908.1 - 7.9e-27 94.2 0.1 1.3e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KNZ74908.1 - 4.2e-20 70.9 0.2 1.1e-19 69.7 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KNZ74908.1 - 5.7e-18 65.5 0.0 1.2e-17 64.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KNZ74908.1 - 2.7e-05 24.4 0.1 0.00011 22.4 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 KNZ74908.1 - 0.17 12.2 0.0 1.1 9.5 0.0 2.0 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Ribosomal_L35Ae PF01247.13 KNZ74909.1 - 6e-42 141.3 0.6 6.7e-42 141.1 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KNZ74909.1 - 0.004 17.0 0.1 1.6 8.7 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain FLILHELTA PF10306.4 KNZ74911.1 - 4.2e-08 33.1 0.0 6.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA AMP-binding PF00501.23 KNZ74913.1 - 6e-29 100.6 0.0 2.3e-26 92.1 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 KNZ74913.1 - 3.3e-28 98.2 0.0 5.1e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KNZ74913.1 - 3.5e-06 26.6 0.0 8.7e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KNZ74913.1 - 0.00055 19.9 0.1 1.2 9.0 0.0 2.6 2 0 0 2 2 2 2 short chain dehydrogenase PP-binding PF00550.20 KNZ74913.1 - 0.002 18.3 0.1 0.0062 16.7 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 KNZ74913.1 - 0.0029 17.6 0.0 0.023 14.7 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KNZ74913.1 - 0.019 15.2 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KNZ74913.1 - 0.042 12.5 0.0 0.11 11.1 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KNZ74913.1 - 0.097 12.3 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 KR domain DapB_N PF01113.15 KNZ74913.1 - 0.22 11.4 0.0 0.5 10.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkH PF02386.11 KNZ74914.1 - 8.6e-82 274.5 13.5 9.4e-81 271.1 3.7 2.2 2 0 0 2 2 2 2 Cation transport protein Isy1 PF06246.7 KNZ74915.1 - 2.3e-74 250.0 0.6 3.2e-74 249.5 0.4 1.2 1 0 0 1 1 1 1 Isy1-like splicing family OEP PF02321.13 KNZ74916.1 - 0.00018 21.1 1.8 0.00037 20.1 1.2 1.4 1 0 0 1 1 1 1 Outer membrane efflux protein Trypsin_2 PF13365.1 KNZ74916.1 - 0.0017 18.3 0.0 0.0046 16.9 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.8 KNZ74916.1 - 0.0036 16.3 0.8 0.0059 15.6 0.1 1.6 2 0 0 2 2 2 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S64 PF08192.6 KNZ74916.1 - 0.004 15.5 0.0 0.0095 14.3 0.0 1.5 2 0 0 2 2 2 1 Peptidase family S64 SAS4 PF15460.1 KNZ74916.1 - 0.048 13.5 0.5 1.4 8.8 0.0 2.8 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 SH3BGR PF04908.10 KNZ74916.1 - 0.11 12.4 0.1 0.78 9.7 0.0 2.1 1 1 1 2 2 2 0 SH3-binding, glutamic acid-rich protein MIF4G PF02854.14 KNZ74917.1 - 3.2e-53 180.2 1.1 5.2e-53 179.5 0.3 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KNZ74917.1 - 4.3e-11 42.5 0.6 4.7e-10 39.1 0.2 2.4 2 0 0 2 2 2 1 MA3 domain LCM PF04072.9 KNZ74918.1 - 3.7e-06 26.6 0.1 4.2e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase ESX-1_EspG PF14011.1 KNZ74918.1 - 0.029 13.6 0.7 0.032 13.4 0.5 1.0 1 0 0 1 1 1 0 EspG family Helitron_like_N PF14214.1 KNZ74919.1 - 1.7e-23 83.3 0.0 2.1e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ74919.1 - 0.0095 15.5 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) Gemini_AL1 PF00799.15 KNZ74919.1 - 0.033 14.0 0.1 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain PIF1 PF05970.9 KNZ74921.1 - 1.1e-102 343.6 0.0 1.3e-102 343.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ74921.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KNZ74921.1 - 0.046 13.2 0.2 0.096 12.1 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.9 KNZ74922.1 - 1.5e-07 29.6 0.0 1.6e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ74922.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PEP_mutase PF13714.1 KNZ74923.1 - 9.8e-45 152.6 5.3 1.3e-44 152.2 3.7 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KNZ74923.1 - 1.1e-20 73.3 0.7 1.6e-20 72.8 0.5 1.2 1 0 0 1 1 1 1 Isocitrate lyase family FMN_dh PF01070.13 KNZ74924.1 - 3.9e-117 391.0 0.1 4.8e-117 390.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KNZ74924.1 - 3.6e-22 77.9 0.0 9.4e-22 76.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KNZ74924.1 - 0.00015 20.8 0.0 0.00024 20.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KNZ74924.1 - 0.0023 16.8 0.0 0.0038 16.1 0.0 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Hexapep PF00132.19 KNZ74926.1 - 3.8e-12 45.1 18.2 6e-08 31.8 1.5 4.3 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KNZ74926.1 - 3.7e-07 29.5 12.1 8e-06 25.3 2.0 3.8 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KNZ74926.1 - 0.004 15.7 0.1 0.0057 15.2 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase Chitin_synth_1 PF01644.12 KNZ74927.1 - 7.3e-79 263.2 0.1 1.1e-78 262.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KNZ74927.1 - 3.5e-19 68.6 3.5 7.2e-18 64.2 0.0 2.7 1 1 1 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.6 KNZ74927.1 - 3.9e-16 58.4 0.1 1.2e-15 56.9 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.1 KNZ74927.1 - 1.4e-07 31.5 0.0 3.3e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KNZ74927.1 - 1.8e-06 27.8 8.1 2.6e-05 24.0 5.6 2.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 HSP70 PF00012.15 KNZ74929.1 - 1.4e-234 779.5 8.5 1.7e-234 779.2 5.9 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KNZ74929.1 - 5.9e-14 51.4 1.4 5.9e-14 51.4 1.0 2.3 3 0 0 3 3 3 1 MreB/Mbl protein DUF1748 PF08520.5 KNZ74929.1 - 0.07 12.7 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) FGGY_C PF02782.11 KNZ74929.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Abhydrolase_3 PF07859.8 KNZ74930.1 - 3.4e-38 131.3 0.1 2.2e-31 109.0 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold APH PF01636.18 KNZ74930.1 - 4.5e-35 121.5 0.0 1.3e-34 120.0 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2424 PF10340.4 KNZ74930.1 - 4.5e-08 32.1 0.0 8.4e-08 31.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Choline_kinase PF01633.15 KNZ74930.1 - 0.00023 20.8 0.0 0.00054 19.5 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KNZ74930.1 - 0.00053 19.2 0.0 0.0012 18.0 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Abhydrolase_5 PF12695.2 KNZ74930.1 - 0.0021 17.7 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_11 PF13414.1 KNZ74931.1 - 1.2e-25 88.9 31.7 8.6e-06 25.3 0.0 10.6 8 2 3 12 12 11 8 TPR repeat TPR_12 PF13424.1 KNZ74931.1 - 9.3e-25 86.3 27.0 2.8e-08 33.5 1.7 8.7 6 3 2 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ74931.1 - 5.9e-23 79.4 16.1 1.3e-05 24.5 0.0 10.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ74931.1 - 5.7e-21 74.6 22.2 0.001 19.3 0.0 10.0 9 2 3 12 12 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ74931.1 - 1.8e-20 71.1 40.5 0.00026 20.6 0.0 13.3 15 0 0 15 15 15 7 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ74931.1 - 6.7e-16 57.3 37.1 0.00056 20.3 0.1 13.6 11 4 6 17 17 13 5 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ74931.1 - 1.3e-14 54.4 46.4 4.1e-05 24.1 0.0 10.7 12 1 1 13 13 11 4 Tetratricopeptide repeat Apc3 PF12895.2 KNZ74931.1 - 1.3e-12 47.6 15.9 0.026 14.6 1.0 6.7 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KNZ74931.1 - 2e-12 45.9 13.1 0.0076 15.9 0.0 9.8 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ74931.1 - 9.1e-12 44.6 29.3 2.6e-05 24.3 0.1 10.4 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ74931.1 - 3.2e-09 35.8 18.7 0.037 13.8 0.0 9.0 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ74931.1 - 5.6e-07 29.2 8.2 3.1 8.2 0.0 8.6 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ74931.1 - 0.00013 21.7 34.7 0.047 13.6 0.2 8.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_4 PF07721.9 KNZ74931.1 - 0.3 11.6 14.2 3.7 8.2 0.1 7.1 8 0 0 8 8 5 0 Tetratricopeptide repeat Ribosomal_S2 PF00318.15 KNZ74932.1 - 9.6e-47 158.9 0.1 6.9e-23 80.9 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 SPA PF08616.5 KNZ74933.1 - 9.6e-34 115.4 0.0 1.5e-32 111.6 0.0 2.6 3 0 0 3 3 3 1 Stabilization of polarity axis Afi1 PF07792.7 KNZ74933.1 - 1.1e-32 113.0 0.0 2.3e-32 112.0 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.4 KNZ74933.1 - 0.0084 14.6 0.0 1.3 7.4 0.0 3.1 2 1 0 2 2 2 2 Transport protein Avl9 HapK PF11639.3 KNZ74933.1 - 0.09 13.4 0.7 11 6.6 0.0 3.2 3 0 0 3 3 3 0 REDY-like protein HapK Fungal_trans PF04082.13 KNZ74934.1 - 1.3e-11 43.8 0.0 2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ74934.1 - 0.0073 16.1 4.1 0.016 15.0 2.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-fist PF00649.13 KNZ74934.1 - 0.047 12.8 2.2 0.13 11.5 1.5 1.7 1 0 0 1 1 1 0 Copper fist DNA binding domain MerR-DNA-bind PF09278.6 KNZ74934.1 - 0.066 13.6 0.8 0.22 11.9 0.1 2.1 2 0 0 2 2 2 0 MerR, DNA binding Peptidase_C50 PF03568.12 KNZ74935.1 - 9.8e-91 304.2 0.0 1.6e-89 300.2 0.0 2.2 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.1 KNZ74935.1 - 9.6e-08 31.8 19.9 0.00017 21.4 3.8 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ74935.1 - 3.4e-05 23.4 11.5 0.0077 15.8 0.0 5.2 4 2 2 6 6 6 3 TPR repeat TPR_8 PF13181.1 KNZ74935.1 - 0.0027 17.3 4.4 3.7 7.5 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat CHAT PF12770.2 KNZ74935.1 - 0.0042 16.2 0.1 0.64 9.0 0.0 2.7 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.1 KNZ74935.1 - 0.021 14.7 8.5 1.9 8.5 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ74935.1 - 1.4 9.0 24.5 0.97 9.5 0.1 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ74935.1 - 7 7.3 7.0 9.7 6.9 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Retrotrans_gag PF03732.12 KNZ74936.1 - 0.16 12.0 0.5 0.23 11.5 0.4 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein PIF1 PF05970.9 KNZ74937.1 - 3e-55 187.6 0.1 3.7e-55 187.3 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ74937.1 - 0.00023 20.8 0.0 0.00035 20.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ74937.1 - 0.0098 15.8 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 KNZ74937.1 - 0.013 14.9 0.1 0.029 13.8 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KNZ74937.1 - 0.024 14.4 0.0 0.055 13.2 0.0 1.5 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KNZ74937.1 - 0.038 14.1 0.2 0.2 11.8 0.1 2.2 2 1 0 2 2 2 0 RNA helicase AAA PF00004.24 KNZ74937.1 - 0.087 13.0 0.2 0.96 9.6 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KNZ74937.1 - 0.097 12.0 0.1 0.25 10.7 0.0 1.6 1 1 0 2 2 2 0 AAA domain Herpes_Helicase PF02689.9 KNZ74938.1 - 2.5e-07 28.9 0.0 2.6e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ74938.1 - 0.049 13.7 0.0 0.08 13.0 0.0 1.4 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Inos-1-P_synth PF01658.12 KNZ74939.1 - 2.6e-05 24.0 0.0 2.7e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Antifungal_prot PF11402.3 KNZ74939.1 - 0.13 12.5 2.8 0.93 9.7 0.0 2.5 2 1 0 2 2 2 0 Antifungal protein Terpene_synth_C PF03936.11 KNZ74941.1 - 1.6e-14 53.8 0.1 2.3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Pkinase_Tyr PF07714.12 KNZ74942.1 - 2e-38 131.9 0.0 2.7e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ74942.1 - 2e-36 125.4 0.0 3.1e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KNZ74942.1 - 0.0025 17.5 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KNZ74942.1 - 0.021 13.7 0.0 0.036 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Peptidase_S8 PF00082.17 KNZ74945.1 - 1e-25 90.4 8.2 2e-25 89.4 5.7 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KNZ74945.1 - 4.8e-07 30.2 0.0 1e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peroxidase_2 PF01328.12 KNZ74946.1 - 1e-21 76.9 0.0 2e-21 75.9 0.0 1.4 1 1 0 1 1 1 1 Peroxidase, family 2 MFS_1 PF07690.11 KNZ74947.1 - 1.2e-41 142.6 48.2 7.6e-37 126.8 18.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KNZ74947.1 - 0.01 15.6 3.2 0.046 13.5 2.2 2.2 1 0 0 1 1 1 0 MFS_1 like family Trep_Strep PF09605.5 KNZ74947.1 - 0.035 13.7 8.7 0.078 12.6 3.4 2.8 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF4500 PF14937.1 KNZ74947.1 - 0.05 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Amidohydro_1 PF01979.15 KNZ74948.1 - 4e-07 30.0 0.0 1.1e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase family NMO PF03060.10 KNZ74948.1 - 0.045 12.8 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase Radical_SAM PF04055.16 KNZ74948.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily MatE PF01554.13 KNZ74949.1 - 6.1e-28 97.4 18.1 9.1e-25 87.1 5.4 3.1 3 1 1 4 4 4 2 MatE COX2_TM PF02790.10 KNZ74949.1 - 0.4 10.6 6.3 0.53 10.2 0.9 2.7 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF552 PF04472.7 KNZ74950.1 - 0.032 14.1 0.1 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF552) DUF1122 PF06557.6 KNZ74950.1 - 0.062 12.4 0.8 0.17 11.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1122) Mito_carr PF00153.22 KNZ74953.1 - 5.2e-23 80.5 6.7 1.8e-10 40.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4229 PF14012.1 KNZ74953.1 - 1.4 8.8 4.5 6.8 6.6 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) DUF1900 PF08954.6 KNZ74954.1 - 2.4e-44 150.1 0.0 5.8e-44 148.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KNZ74954.1 - 2.5e-29 100.6 0.1 4.5e-29 99.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KNZ74954.1 - 1.7e-23 81.5 3.6 2e-08 33.7 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 KNZ74954.1 - 0.027 14.1 0.0 5.8 6.5 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A CCDC144C PF14915.1 KNZ74954.1 - 0.04 12.8 2.8 0.057 12.3 1.9 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Spc42p PF11544.3 KNZ74954.1 - 0.21 11.5 0.8 0.37 10.7 0.5 1.3 1 0 0 1 1 1 0 Spindle pole body component Spc42p DRMBL PF07522.9 KNZ74955.1 - 9.8e-11 41.6 0.0 4.8e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KNZ74955.1 - 1.2e-09 37.9 0.0 5e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KNZ74955.1 - 0.028 14.2 0.0 0.09 12.6 0.0 1.8 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KNZ74955.1 - 0.56 9.8 4.6 7.2 6.2 3.3 2.5 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily zf-MYND PF01753.13 KNZ74956.1 - 1.6e-11 43.8 13.1 1.6e-11 43.8 9.1 1.8 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 KNZ74956.1 - 0.032 14.0 4.6 0.091 12.6 3.2 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Pyr_redox PF00070.22 KNZ74957.1 - 2.8e-12 46.8 1.0 9.6e-09 35.5 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KNZ74957.1 - 1.8e-11 44.3 0.1 2.3e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNZ74957.1 - 2.9e-06 27.4 0.1 0.021 14.8 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KNZ74957.1 - 4e-05 22.6 3.3 0.082 11.7 0.0 3.5 2 1 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KNZ74957.1 - 5.6e-05 22.2 0.1 0.86 8.4 0.1 3.3 2 1 1 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 KNZ74957.1 - 0.00017 21.4 0.1 0.64 9.7 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KNZ74957.1 - 0.0013 17.4 1.0 0.0086 14.7 0.0 2.5 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_7 PF13241.1 KNZ74957.1 - 0.0017 18.5 0.4 3.1 8.0 0.0 2.9 3 0 0 3 3 3 2 Putative NAD(P)-binding TrkA_N PF02254.13 KNZ74957.1 - 0.0046 16.9 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain GIDA PF01134.17 KNZ74957.1 - 0.013 14.4 0.4 2.4 6.9 0.0 3.1 2 1 0 3 3 3 0 Glucose inhibited division protein A K_oxygenase PF13434.1 KNZ74957.1 - 0.017 14.0 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KNZ74957.1 - 0.021 13.9 0.3 0.11 11.5 0.1 2.0 2 0 0 2 2 2 0 Thi4 family GMC_oxred_N PF00732.14 KNZ74958.1 - 3.7e-54 183.8 0.0 4.9e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ74958.1 - 2.4e-33 115.4 0.0 4.8e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KNZ74958.1 - 0.00025 21.0 0.0 0.00079 19.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KNZ74958.1 - 0.0013 17.7 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KNZ74958.1 - 0.0019 17.1 0.0 0.0051 15.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ74958.1 - 0.016 14.0 0.9 0.029 13.2 0.3 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 KNZ74958.1 - 0.024 14.6 0.0 0.62 10.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase dCMP_cyt_deam_1 PF00383.17 KNZ74959.1 - 5.6e-18 64.4 0.1 7e-18 64.1 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 KNZ74959.1 - 1.9e-13 50.5 0.5 1.3e-10 41.3 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 KNZ74959.1 - 0.00025 20.5 1.3 0.15 11.4 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases p450 PF00067.17 KNZ74960.1 - 2.6e-61 207.5 0.0 3.2e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Hira PF07569.6 KNZ74960.1 - 0.029 13.5 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 TUP1-like enhancer of split BNR PF02012.15 KNZ74961.1 - 5.1e-08 31.5 33.7 0.51 10.3 0.0 8.8 8 0 0 8 8 8 6 BNR/Asp-box repeat PSII_BNR PF14870.1 KNZ74961.1 - 0.0012 17.8 1.9 0.59 9.0 0.0 3.7 3 2 1 4 4 4 2 Photosynthesis system II assembly factor YCF48 Fe_dep_repr_C PF02742.10 KNZ74961.1 - 0.15 11.8 0.0 0.41 10.3 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain p450 PF00067.17 KNZ74962.1 - 6.8e-68 229.2 0.0 8.2e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hira PF07569.6 KNZ74962.1 - 0.0062 15.7 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 TUP1-like enhancer of split p450 PF00067.17 KNZ74963.1 - 2.2e-19 69.3 0.0 2.5e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BPL_N PF09825.4 KNZ74964.1 - 2.1e-33 115.6 0.0 9.7e-33 113.4 0.0 1.9 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KNZ74964.1 - 1.4e-21 76.7 0.0 2.8e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ThuA PF06283.6 KNZ74964.1 - 0.07 12.8 0.0 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Trehalose utilisation F-box PF00646.28 KNZ74965.1 - 0.00071 19.1 0.6 0.0016 18.0 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KNZ74965.1 - 0.12 12.1 0.5 0.33 10.6 0.4 1.7 1 0 0 1 1 1 0 F-box-like Lipase_3 PF01764.20 KNZ74967.1 - 6.2e-21 74.4 0.0 7.9e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KNZ74967.1 - 0.0022 17.7 0.1 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KNZ74967.1 - 0.014 14.7 0.0 0.028 13.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF676 PF05057.9 KNZ74967.1 - 0.027 13.7 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KNZ74967.1 - 0.034 14.0 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cutinase PF01083.17 KNZ74967.1 - 0.04 13.6 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_2 PF02230.11 KNZ74967.1 - 0.045 13.1 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase TPR_11 PF13414.1 KNZ74968.1 - 2.1e-34 116.9 21.9 3.1e-16 58.7 1.1 5.5 5 1 1 6 6 5 4 TPR repeat TPR_1 PF00515.23 KNZ74968.1 - 1.6e-24 84.4 6.5 8.4e-05 22.0 0.0 7.6 8 0 0 8 8 7 5 Tetratricopeptide repeat DnaJ PF00226.26 KNZ74968.1 - 1.3e-23 82.5 0.6 2.6e-23 81.5 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.12 KNZ74968.1 - 3.6e-20 70.1 21.1 0.00015 21.4 0.0 8.6 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ74968.1 - 2.1e-14 53.7 22.4 0.0031 18.1 0.1 6.4 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ74968.1 - 2.6e-12 46.4 10.2 3.6e-05 23.5 0.2 5.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ74968.1 - 6.4e-09 36.0 14.6 0.11 12.8 0.0 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KNZ74968.1 - 7.2e-08 32.4 1.1 0.0027 17.8 0.8 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KNZ74968.1 - 6e-07 29.5 18.6 0.33 11.7 0.0 7.7 4 3 4 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ74968.1 - 8.5e-07 28.8 20.2 0.072 13.0 0.6 6.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ74968.1 - 3.3e-05 23.7 5.6 0.69 10.2 0.0 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KNZ74968.1 - 5.7e-05 22.2 1.2 1.1 8.5 0.0 4.5 4 0 0 4 4 4 1 SHNi-TPR MIT PF04212.13 KNZ74968.1 - 0.0011 18.7 3.4 0.73 9.7 0.0 3.7 2 1 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_7 PF13176.1 KNZ74968.1 - 0.0031 17.1 5.4 0.6 10.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ74968.1 - 0.005 16.7 1.4 4.1 7.4 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ74968.1 - 0.0062 16.2 13.9 6.3 6.8 0.0 7.2 9 0 0 9 9 8 1 Tetratricopeptide repeat DUF4398 PF14346.1 KNZ74968.1 - 0.0085 16.1 18.1 1 9.4 0.0 4.8 4 1 0 4 4 4 1 Domain of unknown function (DUF4398) TPR_6 PF13174.1 KNZ74968.1 - 0.036 14.5 6.3 33 5.2 0.0 6.1 7 1 1 8 8 6 0 Tetratricopeptide repeat FadA PF09403.5 KNZ74968.1 - 0.057 13.4 0.1 0.43 10.5 0.0 2.5 3 0 0 3 3 3 0 Adhesion protein FadA Fis1_TPR_C PF14853.1 KNZ74968.1 - 0.31 10.9 3.8 25 4.8 0.0 3.9 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat WD40 PF00400.27 KNZ74970.1 - 1.3e-48 161.1 29.3 3e-11 42.7 0.5 8.5 9 0 0 9 9 9 7 WD domain, G-beta repeat Nup160 PF11715.3 KNZ74970.1 - 1.9e-05 23.0 6.6 0.79 7.7 1.0 4.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 DUF1513 PF07433.6 KNZ74970.1 - 0.006 15.5 0.0 0.78 8.5 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1513) PQQ_3 PF13570.1 KNZ74970.1 - 0.39 11.0 6.8 34 4.8 0.0 5.3 7 1 1 8 8 8 0 PQQ-like domain Mito_carr PF00153.22 KNZ74972.1 - 1.6e-68 226.4 2.1 5.1e-23 80.6 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rbc25 PF08292.7 KNZ74973.1 - 7.7e-33 113.2 0.0 1e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KNZ74973.1 - 2.9e-21 75.3 1.4 4.2e-21 74.8 0.1 1.9 3 0 0 3 3 3 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Trehalase PF01204.13 KNZ74974.1 - 4.9e-100 335.5 6.1 2e-96 323.6 0.2 3.3 2 2 0 2 2 2 2 Trehalase GDE_C PF06202.9 KNZ74974.1 - 0.03 13.0 0.0 0.047 12.4 0.0 1.4 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Aminotran_5 PF00266.14 KNZ74976.1 - 4.9e-18 65.0 0.0 8.7e-18 64.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KNZ74976.1 - 1.6e-10 40.5 0.0 2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KNZ74976.1 - 0.1 11.6 0.0 6.7 5.6 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Sod_Fe_C PF02777.13 KNZ74977.1 - 1.9e-35 120.8 0.0 3.4e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KNZ74977.1 - 1.4e-31 108.5 3.2 2.7e-31 107.6 1.4 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ATP-synt_DE PF00401.15 KNZ74977.1 - 0.51 10.2 4.6 2.3 8.1 2.9 2.0 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain PMI_typeI PF01238.16 KNZ74978.1 - 1.1e-14 54.1 0.1 2.5e-14 53.0 0.1 1.5 1 1 0 1 1 1 1 Phosphomannose isomerase type I EF-hand_like PF09279.6 KNZ74978.1 - 0.069 13.1 0.0 0.086 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like zf-HC5HC2H_2 PF13832.1 KNZ74979.1 - 4.2e-32 110.4 12.5 1.8e-31 108.4 5.8 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KNZ74979.1 - 4e-23 81.3 5.8 4e-23 81.3 4.0 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 KNZ74979.1 - 1.9e-21 77.0 4.2 1.9e-21 77.0 2.9 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like Bromodomain PF00439.20 KNZ74979.1 - 5.1e-17 61.5 0.0 9.9e-17 60.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 KNZ74979.1 - 9.5e-15 53.6 3.1 9.5e-15 53.6 2.2 3.3 3 1 1 4 4 4 1 PHD-finger PWWP PF00855.12 KNZ74979.1 - 1.4e-12 47.6 0.6 3.5e-12 46.3 0.4 1.8 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 KNZ74979.1 - 1.2e-09 37.7 6.0 1.2e-09 37.7 4.2 3.1 3 0 0 3 3 3 1 PHD-finger C1_1 PF00130.17 KNZ74979.1 - 0.0023 17.5 0.3 0.0023 17.5 0.2 2.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 KNZ74979.1 - 5.3 7.1 23.2 0.41 10.6 5.9 3.0 3 0 0 3 3 3 0 RING-like domain PMI_typeI PF01238.16 KNZ74980.1 - 7.7e-115 383.8 0.0 8.8e-115 383.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 KNZ74980.1 - 0.001 18.5 0.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 KNZ74980.1 - 0.0084 15.8 0.0 4.6 6.9 0.0 2.6 3 0 0 3 3 3 2 AraC-like ligand binding domain LptE PF04390.7 KNZ74980.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide-assembly Thioredoxin PF00085.15 KNZ74981.1 - 4.4e-21 74.5 0.0 1.5e-20 72.7 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 KNZ74981.1 - 0.00014 21.9 0.1 0.00056 20.0 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KNZ74981.1 - 0.0034 17.3 0.0 0.0067 16.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 KNZ74981.1 - 0.014 15.4 0.0 0.35 11.0 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.1 KNZ74981.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Glyco_hydro_3 PF00933.16 KNZ74982.1 - 1.1e-76 257.6 0.0 1.6e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KNZ74982.1 - 3.9e-65 219.5 0.0 5.1e-64 215.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KNZ74982.1 - 1.6e-20 72.8 0.5 3.1e-20 71.8 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KNZ74982.1 - 1.3e-11 44.3 0.0 2.6e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain ADH_zinc_N PF00107.21 KNZ74983.1 - 1.5e-29 102.1 0.8 2.3e-29 101.5 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KNZ74983.1 - 2.2e-15 57.6 0.0 4.3e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ74983.1 - 8.3e-14 51.2 0.1 1.7e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Melibiase PF02065.13 KNZ74985.1 - 1.1e-11 44.0 0.0 5.9e-07 28.5 0.0 3.0 1 1 1 2 2 2 2 Melibiase Ran_BP1 PF00638.13 KNZ74986.1 - 0.0004 20.4 0.0 0.00092 19.2 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain YABBY PF04690.8 KNZ74986.1 - 0.16 12.2 0.9 0.29 11.3 0.2 1.7 2 0 0 2 2 2 0 YABBY protein FAM220 PF15487.1 KNZ74986.1 - 0.64 9.3 4.8 1 8.6 3.3 1.3 1 0 0 1 1 1 0 FAM220 family GPI-anchored PF10342.4 KNZ74987.1 - 1.2e-07 32.1 1.4 1.5e-07 31.7 0.1 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RNase_H2_suC PF08615.6 KNZ74988.1 - 9.3e-22 77.3 1.1 1.9e-21 76.3 0.8 1.5 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Dynamin_M PF01031.15 KNZ74989.1 - 2.7e-109 364.5 0.0 4.6e-109 363.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KNZ74989.1 - 2.8e-54 183.4 0.3 9.5e-54 181.7 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 KNZ74989.1 - 3.3e-30 103.8 2.6 2.7e-29 100.9 1.1 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_16 PF13191.1 KNZ74989.1 - 0.0021 18.0 0.0 0.0067 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 KNZ74989.1 - 0.0045 16.9 0.0 0.022 14.6 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KNZ74989.1 - 0.032 14.7 0.0 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein AIG1 PF04548.11 KNZ74989.1 - 0.035 13.1 0.0 6.1 5.8 0.0 2.4 2 0 0 2 2 2 0 AIG1 family BCS1_N PF08740.6 KNZ74990.1 - 5e-29 101.2 0.8 5e-29 101.2 0.5 2.6 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 KNZ74990.1 - 3.3e-15 56.4 0.0 4.9e-14 52.6 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KNZ74990.1 - 0.00056 19.7 0.0 0.0019 18.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ74990.1 - 0.0008 19.4 3.2 0.0013 18.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KNZ74990.1 - 0.0018 19.1 2.3 0.01 16.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KNZ74990.1 - 0.0093 15.5 0.0 0.0093 15.5 0.0 2.3 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 KNZ74990.1 - 0.09 12.4 0.1 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 KNZ74990.1 - 0.3 11.4 0.1 0.3 11.4 0.0 3.3 3 1 0 3 3 2 0 AAA domain Antimicrobial_2 PF08023.7 KNZ74990.1 - 0.35 11.2 1.3 0.79 10.0 0.2 2.1 2 0 0 2 2 2 0 Frog antimicrobial peptide MIP-T3 PF10243.4 KNZ74990.1 - 0.62 8.4 44.5 1 7.7 30.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AAA_11 PF13086.1 KNZ74990.1 - 2.4 7.6 0.0 2.4 7.6 0.0 2.7 2 1 0 2 2 1 0 AAA domain AvrE PF11725.3 KNZ74990.1 - 4 4.3 24.1 5.1 3.9 16.7 1.1 1 0 0 1 1 1 0 Pathogenicity factor DUF3492 PF11997.3 KNZ74990.1 - 5.5 6.4 7.8 12 5.3 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) SYS1 PF09801.4 KNZ74991.1 - 1.2e-26 93.4 0.6 6.1e-18 65.2 0.4 2.0 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network DPPIV_N PF00930.16 KNZ74992.1 - 5.6e-90 301.4 0.3 7.4e-90 301.0 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KNZ74992.1 - 1.1e-37 129.3 2.8 3.8e-18 65.4 0.1 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KNZ74992.1 - 4.1e-07 29.8 0.0 8.5e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KNZ74992.1 - 3.7e-05 23.2 0.4 0.0001 21.8 0.1 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 KNZ74992.1 - 3.7e-05 23.7 0.0 0.0001 22.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KNZ74992.1 - 0.0095 15.3 0.0 0.34 10.3 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 KNZ74992.1 - 0.02 13.3 0.0 0.034 12.6 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Nro1 PF12753.2 KNZ74993.1 - 0.00011 21.3 0.4 0.0079 15.1 0.4 2.3 2 0 0 2 2 2 2 Nuclear pore complex subunit Nro1 Mito_carr PF00153.22 KNZ74994.1 - 5.1e-50 167.1 7.9 3.1e-22 78.0 0.2 4.2 3 1 1 4 4 4 4 Mitochondrial carrier protein HTH_28 PF13518.1 KNZ74994.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain SnoaL_2 PF12680.2 KNZ74995.1 - 1.8e-09 37.8 0.0 2.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 KNZ74995.1 - 7.5e-05 22.3 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_4 PF13577.1 KNZ74995.1 - 0.014 15.3 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Polysacc_deac_1 PF01522.16 KNZ74996.1 - 4.4e-13 48.9 0.0 1.1e-12 47.6 0.0 1.6 1 1 1 2 2 2 1 Polysaccharide deacetylase NUDIX PF00293.23 KNZ74996.1 - 0.011 15.4 0.0 0.031 13.9 0.0 1.8 2 0 0 2 2 2 0 NUDIX domain DUF2194 PF09960.4 KNZ74996.1 - 0.011 13.7 0.1 0.018 13.0 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) STT3 PF02516.9 KNZ74997.1 - 6.5e-136 454.1 31.3 1e-135 453.4 21.7 1.3 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Herpes_Helicase PF02689.9 KNZ74998.1 - 2.9e-07 28.6 0.0 3e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 Helicase Polysacc_deac_1 PF01522.16 KNZ74999.1 - 5.6e-14 51.8 0.0 1.3e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 KNZ74999.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Beta-Casp PF10996.3 KNZ75004.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Beta-Casp domain RNase_H PF00075.19 KNZ75009.1 - 6.3e-12 45.9 0.0 8.1e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 RNase H zf-CSL PF05207.8 KNZ75010.1 - 0.022 14.2 0.9 0.055 12.9 0.6 1.6 1 0 0 1 1 1 0 CSL zinc finger PIF1 PF05970.9 KNZ75011.1 - 4.3e-34 118.0 0.0 5.6e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 KNZ75011.1 - 4.9e-07 27.9 0.0 5.8e-07 27.6 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ75011.1 - 6.5e-05 23.0 0.0 0.00014 21.9 0.0 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain RVP_2 PF08284.6 KNZ75012.1 - 0.052 13.4 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Mating_C PF12737.2 KNZ75013.1 - 2.2e-37 128.9 14.5 3.6e-37 128.2 10.0 1.4 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 Homeobox_KN PF05920.6 KNZ75013.1 - 1.6e-13 50.0 0.8 5.1e-13 48.5 0.0 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 KNZ75013.1 - 0.0097 15.5 0.2 0.13 11.8 0.0 2.8 3 0 0 3 3 3 1 Homeobox domain Homeobox PF00046.24 KNZ75014.1 - 7.1e-15 54.3 0.3 1.4e-14 53.3 0.2 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KNZ75014.1 - 5.5e-06 25.9 0.2 1.7e-05 24.4 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 KNZ75014.1 - 0.049 12.7 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Sterol_MT_C PF08498.5 KNZ75014.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Sterol methyltransferase C-terminal Mitofilin PF09731.4 KNZ75015.1 - 0.035 12.7 8.1 0.049 12.2 5.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Fez1 PF06818.10 KNZ75015.1 - 0.16 11.9 1.1 0.25 11.3 0.8 1.3 1 0 0 1 1 1 0 Fez1 Tape_meas_lam_C PF09718.5 KNZ75015.1 - 0.39 10.6 5.8 3.3 7.6 0.1 4.0 4 0 0 4 4 4 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF883 PF05957.8 KNZ75015.1 - 4.5 7.7 9.6 29 5.1 4.1 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Glyco_transf_8 PF01501.15 KNZ75016.1 - 1.7e-31 109.4 0.0 2.6e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KNZ75016.1 - 0.0033 16.8 0.1 0.0054 16.1 0.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative ABC1 PF03109.11 KNZ75017.1 - 4.4e-23 81.5 0.0 7.7e-13 48.4 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 KNZ75017.1 - 0.072 12.8 0.0 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family HORMA PF02301.13 KNZ75018.1 - 2.4e-23 82.7 0.0 3.3e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 HORMA domain MFS_1 PF07690.11 KNZ75019.1 - 1.7e-38 132.2 40.6 1.1e-37 129.5 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ75019.1 - 1.4e-07 30.4 12.1 1.4e-07 30.4 8.4 3.5 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 KNZ75019.1 - 0.00022 19.7 7.7 0.00022 19.7 5.3 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 KNZ75019.1 - 0.0071 16.1 0.9 0.17 11.7 0.0 3.5 3 2 0 3 3 3 1 MFS_1 like family OATP PF03137.15 KNZ75019.1 - 0.0072 14.4 1.0 0.0072 14.4 0.7 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 KNZ75019.1 - 6.5 4.7 18.5 0.012 13.7 5.0 2.0 2 1 0 2 2 2 0 Transmembrane secretion effector Oxidored_FMN PF00724.15 KNZ75020.1 - 4.3e-58 196.9 0.0 5.6e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fructosamin_kin PF03881.9 KNZ75021.1 - 7.7e-58 195.7 0.0 9.9e-58 195.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KNZ75021.1 - 1.8e-08 34.3 0.0 3.6e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RNA_pol_Rpb2_6 PF00562.23 KNZ75022.1 - 5e-118 394.2 0.1 8.6e-118 393.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KNZ75022.1 - 4.7e-69 231.3 0.0 7e-69 230.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KNZ75022.1 - 6e-49 166.0 0.2 1.6e-48 164.6 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KNZ75022.1 - 1.5e-28 98.8 0.3 4e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KNZ75022.1 - 6.7e-28 96.2 0.4 1.7e-27 95.0 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KNZ75022.1 - 1.4e-23 82.4 0.1 2.9e-23 81.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KNZ75022.1 - 1.5e-21 76.1 0.1 3.1e-21 75.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Lung_7-TM_R PF06814.8 KNZ75023.1 - 2.5e-50 171.1 13.2 3.5e-50 170.6 9.1 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor PX PF00787.19 KNZ75024.1 - 6e-21 74.3 0.2 2e-20 72.6 0.2 1.8 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KNZ75024.1 - 1.8e-07 30.6 5.9 5.1e-05 22.6 1.9 2.9 1 1 2 3 3 3 2 Vps5 C terminal like BAR PF03114.13 KNZ75024.1 - 0.00023 20.7 0.4 1.4 8.3 0.2 3.1 3 0 0 3 3 3 3 BAR domain RmlD_sub_bind PF04321.12 KNZ75025.1 - 1.4e-05 24.1 0.0 1.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KNZ75025.1 - 0.0013 17.4 0.0 0.002 16.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KNZ75025.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KNZ75025.1 - 0.028 13.3 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Myb_DNA-binding PF00249.26 KNZ75026.1 - 1.5e-06 28.1 0.1 0.0024 17.9 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KNZ75026.1 - 0.00012 22.0 1.0 0.0076 16.3 0.1 2.9 2 1 1 3 3 3 1 Myb-like DNA-binding domain Ribonuclease_T2 PF00445.13 KNZ75029.1 - 1.2e-30 106.6 0.1 2.5e-30 105.5 0.1 1.5 1 1 0 1 1 1 1 Ribonuclease T2 family GP3 PF03076.9 KNZ75029.1 - 0.037 13.8 1.2 0.072 12.9 0.1 1.9 2 0 0 2 2 2 0 Equine arteritis virus GP3 Rad51 PF08423.6 KNZ75030.1 - 6.1e-98 326.7 0.0 2e-97 325.1 0.0 1.7 1 1 0 1 1 1 1 Rad51 RecA PF00154.16 KNZ75030.1 - 4.9e-06 25.8 1.2 8.9e-05 21.6 0.8 2.1 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KNZ75030.1 - 4.7e-05 22.6 1.0 0.00021 20.4 0.7 1.9 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.1 KNZ75030.1 - 0.00011 21.6 0.0 0.0004 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain CWC25 PF12542.3 KNZ75031.1 - 2.7e-25 88.6 0.6 2.7e-25 88.6 0.4 3.4 3 0 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.4 KNZ75031.1 - 1.3e-12 47.4 13.0 1.3e-12 47.4 9.0 4.5 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR FRG1 PF06229.7 KNZ75031.1 - 0.0045 16.4 3.5 0.0045 16.4 2.4 2.2 2 0 0 2 2 2 1 FRG1-like family Ion_trans PF00520.26 KNZ75032.1 - 1.5e-06 27.6 2.5 2.3e-06 27.0 1.7 1.3 1 0 0 1 1 1 1 Ion transport protein I_LWEQ PF01608.12 KNZ75034.1 - 4e-64 215.1 9.5 4e-64 215.1 6.6 5.0 4 2 0 5 5 5 1 I/LWEQ domain TcdB_N PF12918.2 KNZ75034.1 - 0.023 14.7 4.5 0.027 14.5 0.2 2.9 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain SURF1 PF02104.10 KNZ75035.1 - 5.1e-58 196.4 0.0 6e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 SURF1 family DDE_Tnp_1 PF01609.16 KNZ75035.1 - 0.057 12.9 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain SIR2 PF02146.12 KNZ75037.1 - 9.4e-33 113.4 0.0 4.8e-21 75.2 0.0 2.3 2 0 0 2 2 2 2 Sir2 family RNA_pol_Rpb6 PF01192.17 KNZ75038.1 - 1.5e-21 75.8 0.1 2.1e-21 75.3 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 RRM_1 PF00076.17 KNZ75039.1 - 2.7e-15 55.7 0.0 3.4e-07 29.8 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ75039.1 - 1.2e-13 50.8 0.1 5.9e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ75039.1 - 3.2e-09 36.4 0.0 1.4e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ParA PF10609.4 KNZ75040.1 - 2.4e-31 107.4 0.1 5.1e-31 106.3 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KNZ75040.1 - 2.2e-05 23.9 0.0 3.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DRIM PF07539.7 KNZ75043.1 - 3.3e-35 120.5 3.4 1e-34 118.9 0.0 3.6 4 0 0 4 4 4 1 Down-regulated in metastasis Ribonuc_2-5A PF06479.7 KNZ75043.1 - 0.0039 17.0 0.2 0.049 13.4 0.0 2.5 2 0 0 2 2 2 1 Ribonuclease 2-5A zf-U1 PF06220.7 KNZ75044.1 - 3.3e-10 39.3 0.8 5e-10 38.7 0.5 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 KNZ75044.1 - 0.22 11.7 2.8 0.72 10.0 1.9 1.8 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding MFS_1 PF07690.11 KNZ75045.1 - 4.1e-13 48.7 36.2 4.8e-13 48.5 23.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KNZ75045.1 - 0.041 13.6 2.0 0.17 11.6 0.0 2.9 3 0 0 3 3 3 0 MFS_1 like family Methyltransf_26 PF13659.1 KNZ75046.1 - 5.3e-12 45.7 0.0 1.3e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KNZ75046.1 - 6.4e-11 42.1 0.0 1.1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.13 KNZ75046.1 - 0.0055 16.2 0.0 2.4 7.6 0.0 2.6 2 1 0 2 2 2 2 DNA methylase SWIM PF04434.12 KNZ75047.1 - 0.00012 21.5 0.3 0.00023 20.5 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-4CXXC_R1 PF10497.4 KNZ75048.1 - 1.3e-08 34.8 10.8 2.9e-08 33.8 7.5 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Tim17 PF02466.14 KNZ75049.1 - 2.7e-30 105.0 6.6 3.3e-30 104.7 4.5 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pyridox_oxidase PF01243.15 KNZ75050.1 - 4.9e-13 48.8 0.0 1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Antimicrobial19 PF08225.6 KNZ75050.1 - 0.027 13.8 1.2 0.058 12.7 0.4 1.8 2 0 0 2 2 2 0 Pseudin antimicrobial peptide Rad9 PF04139.8 KNZ75051.1 - 1.4e-37 129.1 0.0 1.8e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Rad9 DUF4168 PF13767.1 KNZ75052.1 - 0.0099 16.4 1.0 0.036 14.6 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4168) Amidase PF01425.16 KNZ75054.1 - 7e-97 325.0 0.0 8.3e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 Amidase PigN PF04987.9 KNZ75055.1 - 5.9e-103 344.8 27.6 7.7e-103 344.4 19.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KNZ75055.1 - 9.8e-12 44.8 0.1 1e-10 41.5 0.0 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KNZ75055.1 - 1.2e-05 24.6 0.0 2.7e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 KNZ75055.1 - 0.02 14.2 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Cys_Met_Meta_PP PF01053.15 KNZ75056.1 - 1e-131 438.7 0.0 1.2e-131 438.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KNZ75056.1 - 6.3e-11 41.8 0.0 9.8e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KNZ75056.1 - 9.7e-11 41.2 0.4 2.1e-10 40.2 0.3 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KNZ75056.1 - 3.7e-09 35.8 0.2 7.2e-09 34.8 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 KNZ75056.1 - 0.0024 16.2 0.1 0.0064 14.8 0.0 1.6 2 0 0 2 2 2 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 KNZ75056.1 - 0.0031 16.7 0.1 0.047 12.8 0.1 2.3 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 KNZ75056.1 - 0.15 10.6 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein GatB_Yqey PF02637.13 KNZ75058.1 - 0.011 15.4 0.2 0.013 15.2 0.1 1.1 1 0 0 1 1 1 0 GatB domain Prp18 PF02840.10 KNZ75058.1 - 0.072 12.9 0.1 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Prp18 domain DUF3766 PF12611.3 KNZ75059.1 - 0.057 12.9 1.2 0.13 11.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3766) Cys_Met_Meta_PP PF01053.15 KNZ75060.1 - 1.4e-54 184.8 0.1 3e-38 131.1 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme RNase_H PF00075.19 KNZ75061.1 - 9.8e-06 25.9 0.1 7.8e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 RNase H RNase_H PF00075.19 KNZ75063.1 - 0.00019 21.7 0.1 0.00043 20.6 0.1 1.6 1 0 0 1 1 1 1 RNase H zf-AD PF07776.10 KNZ75063.1 - 0.052 13.5 0.5 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Mis14 PF08641.7 KNZ75063.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinetochore protein Mis14 like p450 PF00067.17 KNZ75064.1 - 8.8e-63 212.4 0.0 1e-62 212.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S19 PF00203.16 KNZ75065.1 - 6.7e-22 76.9 0.0 1e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 zf-C3HC4_3 PF13920.1 KNZ75067.1 - 3.4e-05 23.4 7.0 3.4e-05 23.4 4.9 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ75067.1 - 1.6 8.5 15.3 0.35 10.6 5.7 2.6 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 KNZ75067.1 - 2.8 7.6 18.0 0.044 13.4 5.8 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L37 PF08561.5 KNZ75068.1 - 2e-16 59.3 0.5 5.7e-16 57.8 0.4 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 ADH_N PF08240.7 KNZ75069.1 - 3.2e-28 97.6 2.8 3.2e-28 97.6 2.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KNZ75069.1 - 6.3e-23 80.7 0.5 1.9e-22 79.1 0.4 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Gag_p15 PF08723.5 KNZ75069.1 - 0.11 12.4 0.0 0.56 10.2 0.0 2.0 2 0 0 2 2 2 0 Gag protein p15 Ribonuclease_T2 PF00445.13 KNZ75069.1 - 0.17 11.5 0.9 0.26 10.8 0.1 1.6 2 0 0 2 2 2 0 Ribonuclease T2 family ADH_N PF08240.7 KNZ75070.1 - 7.2e-28 96.5 2.7 7.2e-28 96.5 1.9 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KNZ75070.1 - 1.6e-24 85.9 0.4 4.8e-24 84.3 0.3 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ribonuclease_T2 PF00445.13 KNZ75070.1 - 0.33 10.5 1.2 0.36 10.4 0.1 1.5 2 0 0 2 2 2 0 Ribonuclease T2 family Choline_transpo PF04515.7 KNZ75071.1 - 1e-26 93.5 7.1 1e-26 93.5 4.9 1.9 2 1 0 2 2 2 1 Plasma-membrane choline transporter DUF4164 PF13747.1 KNZ75072.1 - 0.019 15.1 0.0 0.075 13.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) FAM177 PF14774.1 KNZ75072.1 - 0.064 13.1 0.3 0.82 9.6 0.0 2.3 2 0 0 2 2 2 0 FAM177 family DUF1504 PF07399.6 KNZ75072.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1504) DIM1 PF02966.11 KNZ75074.1 - 2.5e-39 133.8 0.1 3.6e-29 100.9 0.0 2.0 1 1 1 2 2 2 2 Mitosis protein DIM1 Thioredoxin PF00085.15 KNZ75074.1 - 0.0003 20.4 0.0 0.00037 20.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Macoilin PF09726.4 KNZ75075.1 - 1.3 7.1 4.8 1.8 6.7 3.3 1.1 1 0 0 1 1 1 0 Transmembrane protein KAR9 PF08580.5 KNZ75075.1 - 1.6 6.8 6.0 1.9 6.6 4.1 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF566 PF04484.7 KNZ75075.1 - 7 6.0 11.1 9.7 5.6 7.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) FYRN PF05964.9 KNZ75077.1 - 0.029 13.7 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 F/Y-rich N-terminus Retrotrans_gag PF03732.12 KNZ75082.1 - 0.00066 19.7 0.1 0.0023 17.9 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein Tmemb_14 PF03647.8 KNZ75085.1 - 0.0032 17.8 1.0 0.0043 17.4 0.6 1.4 1 1 1 2 2 2 1 Transmembrane proteins 14C VPEP PF07589.6 KNZ75085.1 - 0.03 14.2 0.4 0.03 14.2 0.3 2.7 3 0 0 3 3 3 0 PEP-CTERM motif Pyr_redox_2 PF07992.9 KNZ75086.1 - 0.017 14.9 0.0 0.2 11.5 0.0 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cation_efflux PF01545.16 KNZ75087.1 - 2e-77 260.0 12.5 2.5e-77 259.7 8.6 1.0 1 0 0 1 1 1 1 Cation efflux family WD40 PF00400.27 KNZ75089.1 - 3.5e-19 67.9 7.5 1.5e-05 24.6 0.3 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KNZ75089.1 - 0.00025 19.9 0.7 0.033 12.9 0.2 3.2 1 1 1 2 2 2 1 Nup133 N terminal like Coatomer_WDAD PF04053.9 KNZ75089.1 - 0.019 13.7 0.0 2.4 6.8 0.0 2.3 1 1 1 2 2 2 0 Coatomer WD associated region DUF1192 PF06698.6 KNZ75089.1 - 0.032 14.0 0.2 0.081 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DnaJ PF00226.26 KNZ75090.1 - 8.5e-20 70.2 0.2 1.3e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain SH3_1 PF00018.23 KNZ75092.1 - 3.3e-18 64.8 2.3 2.3e-08 33.2 0.1 2.7 2 1 0 2 2 2 2 SH3 domain SAM_1 PF00536.25 KNZ75092.1 - 5.4e-13 48.9 0.0 8.7e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 KNZ75092.1 - 1e-12 47.4 3.0 4.9e-06 26.0 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SAM_2 PF07647.12 KNZ75092.1 - 9.8e-12 44.5 0.0 1.7e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 KNZ75092.1 - 7.8e-11 41.3 0.5 4.6e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain RA PF00788.18 KNZ75092.1 - 6.1e-10 39.4 0.0 1.2e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.6 KNZ75092.1 - 0.0067 16.5 5.6 0.43 10.8 0.3 3.1 3 0 0 3 3 3 2 Bacterial SH3 domain SlyX PF04102.7 KNZ75092.1 - 0.031 14.6 0.4 0.099 13.0 0.3 1.9 1 0 0 1 1 1 0 SlyX HALZ PF02183.13 KNZ75092.1 - 0.046 13.4 0.1 0.092 12.4 0.1 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper ADIP PF11559.3 KNZ75092.1 - 0.083 12.7 0.8 0.18 11.6 0.4 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding BRAP2 PF07576.7 KNZ75093.1 - 3.6e-23 81.2 0.0 8e-23 80.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 KNZ75093.1 - 1.9e-19 69.5 5.1 3.6e-19 68.6 3.5 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein RRM_1 PF00076.17 KNZ75093.1 - 0.0013 18.2 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HemX PF04375.9 KNZ75093.1 - 0.0079 14.8 3.5 0.013 14.1 2.4 1.4 1 0 0 1 1 1 1 HemX Mnd1 PF03962.10 KNZ75093.1 - 0.019 14.6 11.5 0.034 13.8 8.0 1.3 1 0 0 1 1 1 0 Mnd1 family RRM_5 PF13893.1 KNZ75093.1 - 0.045 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WXG100 PF06013.7 KNZ75093.1 - 0.099 12.6 2.7 0.17 11.9 1.5 1.7 1 1 0 1 1 1 0 Proteins of 100 residues with WXG SPX PF03105.14 KNZ75093.1 - 0.11 12.2 7.6 0.15 11.7 5.3 1.2 1 0 0 1 1 1 0 SPX domain DUF1136 PF06582.7 KNZ75093.1 - 0.29 10.8 2.0 0.45 10.2 0.1 2.4 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) DUF4407 PF14362.1 KNZ75093.1 - 0.39 9.6 13.0 0.56 9.1 8.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3573 PF12097.3 KNZ75093.1 - 0.65 8.5 2.8 0.96 7.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) V_ATPase_I PF01496.14 KNZ75093.1 - 0.85 7.3 8.4 1.1 7.0 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.4 KNZ75093.1 - 1.6 6.9 14.8 2.4 6.3 10.2 1.2 1 0 0 1 1 1 0 Transmembrane protein NUDIX PF00293.23 KNZ75094.1 - 5.7e-10 38.9 0.0 9.4e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Vma12 PF11712.3 KNZ75095.1 - 8.1e-15 54.7 0.2 1.2e-14 54.2 0.1 1.3 1 1 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Tmemb_14 PF03647.8 KNZ75095.1 - 0.0033 17.7 0.1 0.0061 16.9 0.1 1.4 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF1469 PF07332.6 KNZ75095.1 - 0.023 14.4 0.1 0.03 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) CAAD PF14159.1 KNZ75095.1 - 0.032 13.8 0.7 0.06 12.9 0.3 1.5 1 1 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase COX3 PF00510.13 KNZ75095.1 - 0.045 13.2 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit III DUF1003 PF06210.6 KNZ75095.1 - 0.054 13.4 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) SieB PF14163.1 KNZ75095.1 - 0.11 12.0 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B Atx10homo_assoc PF09759.4 KNZ75096.1 - 4.9e-22 77.5 0.1 5.4e-21 74.2 0.0 2.5 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Leo1 PF04004.8 KNZ75097.1 - 4.1e-52 176.3 0.2 4.1e-52 176.3 0.1 2.0 2 0 0 2 2 2 1 Leo1-like protein Prenyltrans PF00432.16 KNZ75100.1 - 4e-29 99.8 8.1 2e-10 40.0 0.3 5.1 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 KNZ75100.1 - 6.1e-18 64.8 0.3 2.9e-09 36.9 0.1 5.6 3 2 3 6 6 6 5 Prenyltransferase-like Prenyltrans_2 PF13249.1 KNZ75100.1 - 2.3e-17 63.4 0.4 1.9e-09 37.9 0.1 4.7 2 2 3 5 5 5 5 Prenyltransferase-like Pec_lyase PF09492.5 KNZ75100.1 - 4.1e-05 22.8 0.4 0.34 10.0 0.0 4.1 4 1 1 5 5 5 2 Pectic acid lyase Actin PF00022.14 KNZ75101.1 - 3.3e-34 117.9 0.0 6.5e-34 116.9 0.0 1.4 1 1 0 1 1 1 1 Actin Ribosomal_L7Ae PF01248.21 KNZ75102.1 - 1.3e-23 82.3 0.0 1.5e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DNA_pol_B PF00136.16 KNZ75103.1 - 4.3e-130 434.6 1.4 4.5e-100 335.6 0.1 2.1 1 1 1 2 2 2 2 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KNZ75103.1 - 5.2e-88 295.0 0.0 9.9e-88 294.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KNZ75103.1 - 5.1e-23 80.8 8.2 5.1e-23 80.8 5.7 1.7 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KNZ75103.1 - 0.0052 16.6 0.1 0.018 14.8 0.1 2.0 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.8 KNZ75103.1 - 0.014 14.0 2.5 0.13 10.9 0.1 2.4 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.4 KNZ75103.1 - 0.029 13.8 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_A_exo1 PF01612.15 KNZ75103.1 - 0.077 12.4 0.1 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 3'-5' exonuclease C1_1 PF00130.17 KNZ75103.1 - 0.61 9.8 5.6 0.23 11.1 1.6 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PMM PF03332.8 KNZ75104.1 - 1.6e-107 358.0 0.4 1.9e-107 357.8 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KNZ75104.1 - 3.6e-05 23.4 0.0 0.00084 18.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 KNZ75104.1 - 0.053 12.5 0.0 0.067 12.2 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Hydrolase PF00702.21 KNZ75104.1 - 0.065 13.6 0.0 0.2 12.0 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ank_5 PF13857.1 KNZ75105.1 - 0.051 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) TRAUB PF08164.7 KNZ75106.1 - 1.1e-26 92.6 0.0 3.1e-26 91.2 0.0 1.8 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KNZ75106.1 - 1.5e-22 80.1 0.0 1.5e-22 80.1 0.0 2.8 2 2 1 3 3 3 1 Apoptosis antagonizing transcription factor PX PF00787.19 KNZ75107.1 - 3.2e-24 84.8 0.2 4.4e-23 81.2 0.0 2.5 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KNZ75107.1 - 3.8e-09 36.1 10.6 4.6e-05 22.7 1.6 2.2 2 0 0 2 2 2 2 Vps5 C terminal like GreA_GreB_N PF03449.10 KNZ75107.1 - 0.045 13.8 0.5 0.045 13.8 0.3 3.3 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal BAR PF03114.13 KNZ75107.1 - 0.25 10.8 9.4 0.013 15.0 1.5 2.0 2 0 0 2 2 2 0 BAR domain AAA_33 PF13671.1 KNZ75108.1 - 1.7e-14 53.9 0.0 1e-13 51.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ75108.1 - 4.6e-05 24.2 0.0 6.8e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KNZ75108.1 - 7.6e-05 22.0 0.0 0.071 12.3 0.0 2.2 1 1 1 2 2 2 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KNZ75108.1 - 0.0017 17.5 0.0 0.039 13.0 0.0 2.2 1 1 1 2 2 2 1 Zeta toxin AAA_22 PF13401.1 KNZ75108.1 - 0.0052 16.9 0.0 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain tRNA_lig_kinase PF08303.6 KNZ75108.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain AAA_18 PF13238.1 KNZ75108.1 - 0.013 15.8 0.0 0.022 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 KNZ75108.1 - 0.02 13.6 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit ATP_bind_1 PF03029.12 KNZ75108.1 - 0.036 13.6 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.15 KNZ75108.1 - 0.064 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_14 PF13173.1 KNZ75108.1 - 0.08 12.8 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_11 PF13414.1 KNZ75109.1 - 1.8e-21 75.5 7.3 2.4e-12 46.3 0.2 3.8 3 1 1 4 4 4 3 TPR repeat TPR_16 PF13432.1 KNZ75109.1 - 1.7e-15 57.1 2.3 4.6e-07 30.3 0.0 3.1 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ75109.1 - 7.5e-15 53.5 7.5 6.3e-08 31.9 0.0 5.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ75109.1 - 7.7e-15 53.7 1.2 1.9e-08 33.5 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ75109.1 - 9.8e-15 53.4 0.4 0.0097 16.0 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ75109.1 - 1.2e-12 47.5 5.1 1.6e-05 24.7 0.2 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ75109.1 - 1.4e-10 41.3 1.7 0.00017 21.8 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ75109.1 - 1.7e-09 37.4 4.9 0.00021 21.6 0.0 4.5 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ75109.1 - 6.7e-07 28.6 5.0 0.00067 19.2 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ75109.1 - 1.2e-06 27.8 2.7 0.00052 19.5 0.0 4.5 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ75109.1 - 5.2e-06 26.2 5.8 0.12 12.3 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KNZ75109.1 - 1.4e-05 25.1 0.4 0.0012 18.9 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KNZ75109.1 - 0.00021 21.5 0.5 0.038 14.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 KNZ75109.1 - 0.00024 20.2 0.4 0.00032 19.8 0.3 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc5 PF12862.2 KNZ75109.1 - 0.00031 20.5 0.1 0.00057 19.6 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_20 PF14561.1 KNZ75109.1 - 0.0037 17.3 1.0 0.21 11.7 0.0 2.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ75109.1 - 0.0062 16.3 0.5 0.92 9.3 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KNZ75109.1 - 0.0093 15.8 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 KNZ75109.1 - 0.025 14.4 2.8 5.8 6.8 0.0 3.2 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.9 KNZ75109.1 - 0.035 14.5 5.5 0.71 10.4 0.1 4.2 4 1 1 5 5 4 0 Tetratricopeptide repeat DUF3856 PF12968.2 KNZ75109.1 - 0.066 13.0 0.3 1.7 8.4 0.0 2.6 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.7 KNZ75109.1 - 0.091 12.5 0.0 0.95 9.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Tim17 PF02466.14 KNZ75110.1 - 2.9e-24 85.5 7.3 3.6e-24 85.2 5.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Velvet PF11754.3 KNZ75111.1 - 5.7e-28 97.9 0.0 9.1e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Cytochrom_C1 PF02167.10 KNZ75112.1 - 7.1e-86 287.3 0.0 8.5e-86 287.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KNZ75112.1 - 0.00052 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 KNZ75112.1 - 0.011 16.5 0.2 0.032 15.0 0.1 1.9 2 1 0 2 2 2 0 Cytochrome c SAC3_GANP PF03399.11 KNZ75113.1 - 1.1e-56 191.5 1.5 2e-56 190.8 1.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KNZ75113.1 - 9.4e-08 31.9 0.1 2.5e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 tRNA_int_endo PF01974.12 KNZ75114.1 - 3.1e-16 58.9 0.2 6.1e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KNZ75114.1 - 0.00058 19.3 0.1 0.0033 16.9 0.0 2.1 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain WD40 PF00400.27 KNZ75115.1 - 3.3e-17 61.6 9.4 5.9e-06 25.9 0.1 6.5 5 1 0 5 5 5 5 WD domain, G-beta repeat F-box-like PF12937.2 KNZ75116.1 - 6.3e-05 22.6 0.3 0.00023 20.8 0.2 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ75116.1 - 0.098 12.3 0.6 0.66 9.7 0.0 2.8 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.2 KNZ75116.1 - 2.7 7.7 6.1 9.9 5.9 0.0 4.4 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Ribosomal_S27 PF01599.14 KNZ75117.1 - 4.9e-27 93.4 1.9 1e-26 92.4 1.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 KNZ75117.1 - 2.4e-19 68.4 1.0 4.9e-19 67.4 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 KNZ75117.1 - 5.4e-10 38.8 0.0 1.3e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KNZ75117.1 - 0.0038 17.0 0.1 0.0073 16.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF971 PF06155.7 KNZ75117.1 - 0.015 15.7 0.1 0.045 14.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF971) IBR PF01485.16 KNZ75117.1 - 0.041 13.7 0.4 0.077 12.8 0.3 1.5 1 0 0 1 1 1 0 IBR domain Rep_fac_C PF08542.6 KNZ75118.1 - 4.3e-21 74.7 0.1 1.4e-20 73.0 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.24 KNZ75118.1 - 5.2e-18 65.5 0.0 9.1e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KNZ75118.1 - 1.4e-16 60.5 0.0 8.6e-15 54.7 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KNZ75118.1 - 1.6e-09 37.0 0.0 9.5e-07 27.8 0.0 2.3 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KNZ75118.1 - 3.7e-08 33.3 0.1 1.1e-07 31.8 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KNZ75118.1 - 9.9e-07 28.9 0.5 0.055 13.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 KNZ75118.1 - 4.1e-06 26.4 0.0 1.2e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 KNZ75118.1 - 8.3e-06 24.9 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 KNZ75118.1 - 1.3e-05 24.9 0.2 0.00044 19.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 KNZ75118.1 - 1.5e-05 24.6 0.1 4.8e-05 22.9 0.1 1.8 3 0 0 3 3 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 KNZ75118.1 - 2e-05 24.6 0.0 0.00055 19.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KNZ75118.1 - 2.2e-05 23.6 0.0 8.1e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 KNZ75118.1 - 4.7e-05 23.0 0.7 0.00033 20.2 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KNZ75118.1 - 0.00011 21.9 0.4 0.0046 16.6 0.1 3.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KNZ75118.1 - 0.0012 18.4 0.0 0.0031 17.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KNZ75118.1 - 0.0012 18.4 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KNZ75118.1 - 0.0024 17.3 0.1 0.075 12.5 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 KNZ75118.1 - 0.0036 16.7 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 KNZ75118.1 - 0.0051 16.5 0.1 0.0094 15.6 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 KNZ75118.1 - 0.0066 17.2 0.0 0.021 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KNZ75118.1 - 0.0069 16.3 0.0 0.02 14.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain Methyltransf_31 PF13847.1 KNZ75118.1 - 0.007 15.9 0.2 0.014 14.9 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain AAA_25 PF13481.1 KNZ75118.1 - 0.0084 15.5 0.1 0.046 13.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KNZ75118.1 - 0.011 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KNZ75118.1 - 0.018 14.8 0.1 0.16 11.8 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit T2SE PF00437.15 KNZ75118.1 - 0.026 13.4 0.0 0.055 12.3 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein CobA_CobO_BtuR PF02572.10 KNZ75118.1 - 0.035 13.7 0.3 1.7 8.2 0.1 2.4 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_10 PF12846.2 KNZ75118.1 - 0.035 13.5 0.1 2.4 7.5 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain ABC_tran PF00005.22 KNZ75118.1 - 0.038 14.2 0.0 0.72 10.1 0.0 2.5 2 1 0 2 2 2 0 ABC transporter SNF2_N PF00176.18 KNZ75118.1 - 0.046 12.5 0.1 0.13 11.0 0.1 1.9 1 1 0 1 1 1 0 SNF2 family N-terminal domain DUF2075 PF09848.4 KNZ75118.1 - 0.049 12.5 0.1 0.29 10.0 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 KNZ75118.1 - 0.051 12.7 0.0 0.25 10.4 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI DALR_1 PF05746.10 KNZ75118.1 - 0.096 12.6 1.9 0.6 10.0 0.1 2.8 2 2 1 3 3 3 0 DALR anticodon binding domain Zw10 PF06248.8 KNZ75119.1 - 8.3e-19 67.1 0.0 1.5e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 KNZ75119.1 - 5.4e-10 38.9 0.0 1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Tweety PF04906.8 KNZ75119.1 - 0.065 11.6 0.6 0.19 10.1 0.3 1.8 2 0 0 2 2 2 0 Tweety NPV_P10 PF05531.7 KNZ75119.1 - 0.12 12.6 1.3 1.5 9.1 0.3 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 KNZ75119.1 - 0.13 12.0 8.1 0.32 10.8 2.9 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RED_N PF07808.8 KNZ75120.1 - 2.3e-14 53.2 9.7 5.8e-14 51.8 6.7 1.7 1 0 0 1 1 1 1 RED-like protein N-terminal region NIR_SIR PF01077.17 KNZ75121.1 - 2.4e-48 163.4 0.0 3.6e-41 140.1 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KNZ75121.1 - 8.9e-35 118.1 0.0 4.6e-16 58.2 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KNZ75121.1 - 2e-25 89.4 0.1 3.4e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin PIG-L PF02585.12 KNZ75122.1 - 4e-22 79.0 0.0 5.5e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Aminotran_5 PF00266.14 KNZ75124.1 - 3.3e-20 72.1 0.0 4e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 KNZ75124.1 - 0.0052 16.6 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain Aminotran_5 PF00266.14 KNZ75125.1 - 1.1e-22 80.3 0.0 1.5e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KNZ75125.1 - 0.0056 15.6 0.0 0.02 13.8 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KNZ75125.1 - 0.011 14.0 0.0 0.019 13.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.14 KNZ75125.1 - 0.093 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain DUF2644 PF10841.3 KNZ75126.1 - 0.041 13.9 0.0 0.05 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) Atg14 PF10186.4 KNZ75126.1 - 0.044 12.7 1.7 0.044 12.7 1.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SIT PF15330.1 KNZ75126.1 - 0.086 12.9 0.7 0.2 11.8 0.5 1.7 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4500 PF14937.1 KNZ75126.1 - 0.13 12.0 0.3 0.27 11.0 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4500) Paramyxo_NS_C PF02725.9 KNZ75126.1 - 0.16 11.5 1.9 0.19 11.3 1.3 1.1 1 0 0 1 1 1 0 Non-structural protein C SHR3_chaperone PF08229.6 KNZ75126.1 - 0.16 10.8 0.5 0.2 10.5 0.3 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 DUF2762 PF10960.3 KNZ75126.1 - 4.5 7.0 12.2 1.7 8.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2762) CTD_bind PF04818.8 KNZ75127.1 - 0.019 15.2 0.0 0.044 14.0 0.0 1.7 1 1 0 1 1 1 0 RNA polymerase II-binding domain. DUF1777 PF08648.7 KNZ75127.1 - 0.97 9.1 18.9 1.7 8.3 13.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) PAP2 PF01569.16 KNZ75128.1 - 2.1e-09 37.1 2.1 2.5e-09 36.8 1.5 1.2 1 0 0 1 1 1 1 PAP2 superfamily SNF2_N PF00176.18 KNZ75129.1 - 3.5e-18 65.4 0.2 3.5e-14 52.2 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 KNZ75129.1 - 1.4e-14 53.9 3.9 1e-13 51.1 0.0 2.9 3 0 0 3 3 3 1 C-5 cytosine-specific DNA methylase zf-RING_5 PF14634.1 KNZ75129.1 - 0.0024 17.5 2.9 0.0024 17.5 2.0 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KNZ75129.1 - 0.2 11.7 11.8 0.025 14.5 2.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cript PF10235.4 KNZ75130.1 - 3.1e-22 78.7 7.0 3.4e-22 78.5 4.8 1.0 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT DUF2039 PF10217.4 KNZ75130.1 - 0.033 14.2 6.7 0.045 13.7 4.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-ribbon_3 PF13248.1 KNZ75130.1 - 0.21 10.8 6.6 2 7.7 2.7 2.3 2 0 0 2 2 2 0 zinc-ribbon domain stn_TNFRSF12A PF12191.3 KNZ75130.1 - 0.37 10.8 2.0 0.44 10.5 1.4 1.2 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Prok-RING_1 PF14446.1 KNZ75130.1 - 0.4 10.4 7.8 1.3 8.7 0.1 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zinc_ribbon_2 PF13240.1 KNZ75130.1 - 0.45 10.0 10.2 3 7.4 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 KNZ75130.1 - 1.1 9.1 7.2 4.2 7.2 2.5 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like C1_1 PF00130.17 KNZ75130.1 - 4.7 7.0 9.1 22 4.8 3.5 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-dskA_traR PF01258.12 KNZ75130.1 - 5.6 6.7 6.8 3.9 7.3 0.1 2.7 2 1 1 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Sar8_2 PF03058.9 KNZ75130.1 - 6.8 7.0 7.4 16 5.9 5.1 1.7 1 1 0 1 1 1 0 Sar8.2 family XPA_N PF01286.13 KNZ75130.1 - 9 6.0 6.7 4.7 6.9 0.4 2.6 2 1 0 2 2 2 0 XPA protein N-terminal Methyltransf_16 PF10294.4 KNZ75132.1 - 8.4e-17 61.1 0.0 1.1e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.10 KNZ75132.1 - 0.0084 15.2 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_18 PF12847.2 KNZ75132.1 - 0.033 14.7 0.0 0.069 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Fe-ADH_2 PF13685.1 KNZ75132.1 - 0.054 12.7 0.1 2.1 7.5 0.0 2.4 3 0 0 3 3 3 0 Iron-containing alcohol dehydrogenase DUF938 PF06080.7 KNZ75132.1 - 0.078 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DUF3932 PF13068.1 KNZ75132.1 - 0.094 12.8 0.2 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3932) MTS PF05175.9 KNZ75132.1 - 0.14 11.4 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain WD40 PF00400.27 KNZ75133.1 - 3.7e-40 134.3 13.6 3e-08 33.2 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF3279 PF11682.3 KNZ75133.1 - 0.0087 15.6 3.0 0.18 11.3 0.1 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3279) Nucleoporin_N PF08801.6 KNZ75133.1 - 0.0087 14.8 0.0 0.54 8.9 0.0 2.3 2 0 0 2 2 2 1 Nup133 N terminal like zf-ribbon_3 PF13248.1 KNZ75133.1 - 0.031 13.4 7.7 6.1 6.1 0.6 3.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-CW PF07496.10 KNZ75133.1 - 0.072 12.8 2.5 0.23 11.2 0.2 2.8 3 0 0 3 3 3 0 CW-type Zinc Finger zinc_ribbon_2 PF13240.1 KNZ75133.1 - 0.12 11.9 5.3 9.8 5.8 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.2 KNZ75133.1 - 0.17 11.7 8.2 1.7 8.5 1.5 3.5 1 1 1 2 2 2 0 Double zinc ribbon Zn_ribbon_recom PF13408.1 KNZ75133.1 - 0.48 10.7 6.5 2.1 8.6 0.1 3.2 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-BED PF02892.10 KNZ75133.1 - 1.8 8.3 10.2 2 8.2 0.2 3.5 3 0 0 3 3 3 0 BED zinc finger DUF4451 PF14616.1 KNZ75133.1 - 2.1 8.1 9.5 0.63 9.8 0.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4451) DNA_RNApol_7kD PF03604.8 KNZ75133.1 - 3.9 7.0 6.3 21 4.7 0.0 3.3 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit SIR2 PF02146.12 KNZ75134.1 - 1.7e-18 66.9 0.0 4.3e-18 65.6 0.0 1.7 1 1 0 1 1 1 1 Sir2 family Zn_clus PF00172.13 KNZ75135.1 - 2.5e-12 46.4 42.7 6.2e-05 22.8 2.0 4.2 3 1 1 4 4 4 4 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.16 KNZ75136.1 - 1.2e-06 27.9 0.0 2.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.16 KNZ75137.1 - 3.2e-07 29.8 0.0 5.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 BCS1_N PF08740.6 KNZ75138.1 - 3.5e-31 108.2 0.6 5.8e-31 107.5 0.4 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KNZ75138.1 - 9.2e-18 64.7 0.0 2.5e-17 63.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNZ75138.1 - 0.00083 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KNZ75138.1 - 0.00086 20.1 0.1 0.0016 19.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KNZ75138.1 - 0.0025 16.7 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 KNZ75138.1 - 0.03 13.4 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 KNZ75138.1 - 0.033 13.9 0.0 0.15 11.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KNZ75138.1 - 0.042 13.7 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KNZ75138.1 - 0.057 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KNZ75138.1 - 0.062 12.8 0.2 0.18 11.3 0.2 1.7 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KNZ75138.1 - 0.068 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KNZ75138.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KNZ75138.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KNZ75138.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4327 PF14217.1 KNZ75138.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) Carb_kinase PF01256.12 KNZ75139.1 - 2.8e-50 170.8 0.0 3.3e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KNZ75139.1 - 0.026 13.6 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase PGM_PMM_I PF02878.11 KNZ75140.1 - 1e-36 125.4 0.1 1.7e-36 124.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KNZ75140.1 - 5.6e-25 87.5 0.0 1.2e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KNZ75140.1 - 5.6e-15 55.5 0.0 1.8e-14 53.9 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KNZ75140.1 - 1.2e-07 31.6 0.0 2.8e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PAP2 PF01569.16 KNZ75141.1 - 2e-09 37.1 6.1 4.7e-09 36.0 4.3 1.6 1 1 0 1 1 1 1 PAP2 superfamily Chromo PF00385.19 KNZ75142.1 - 0.014 15.0 1.5 0.027 14.1 1.1 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Chromo PF00385.19 KNZ75143.1 - 0.00078 19.0 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KNZ75143.1 - 0.0035 17.0 0.0 0.006 16.2 0.0 1.5 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Pantoate_ligase PF02569.10 KNZ75144.1 - 1.2e-80 270.3 0.0 2.9e-80 269.0 0.0 1.6 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase MBOAT_2 PF13813.1 KNZ75145.1 - 2.5e-17 62.6 3.6 7.8e-17 61.1 2.5 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Methyltransf_25 PF13649.1 KNZ75146.1 - 1.4e-05 25.3 0.0 3.4e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ75146.1 - 0.0034 17.1 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ75146.1 - 0.11 12.9 0.0 0.39 11.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ75147.1 - 1.4e-06 28.5 0.0 5.4e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ75147.1 - 0.00032 20.4 0.0 0.00053 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_20 PF12147.3 KNZ75147.1 - 0.17 10.7 0.0 0.75 8.6 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase HMG_CoA_synt_C PF08540.5 KNZ75148.1 - 8.9e-86 287.8 0.1 1.1e-85 287.5 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KNZ75148.1 - 5.9e-82 273.3 0.0 8.6e-82 272.8 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.5 KNZ75148.1 - 0.002 17.7 0.1 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 KNZ75148.1 - 0.0032 17.4 0.0 0.064 13.2 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF3641 PF12345.3 KNZ75148.1 - 0.0073 16.1 0.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3641) HMG_CoA_synt_C PF08540.5 KNZ75149.1 - 2.2e-85 286.5 0.1 2.8e-85 286.2 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KNZ75149.1 - 7.2e-82 273.1 0.0 1.1e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.5 KNZ75149.1 - 0.0013 18.3 0.1 0.007 16.0 0.1 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 KNZ75149.1 - 0.0045 16.9 0.0 0.06 13.3 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF3641 PF12345.3 KNZ75149.1 - 0.0078 16.0 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3641) Ribonuc_P_40 PF08584.6 KNZ75150.1 - 1.1e-25 90.2 0.0 3.2e-25 88.6 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit VPS9 PF02204.13 KNZ75152.1 - 2e-31 108.0 0.1 3.5e-31 107.3 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KNZ75152.1 - 7.7e-09 34.8 0.1 2.2e-08 33.4 0.1 1.8 1 0 0 1 1 1 1 CUE domain DMA PF03474.9 KNZ75152.1 - 0.00024 20.8 0.0 0.00049 19.8 0.0 1.5 1 0 0 1 1 1 1 DMRTA motif MFS_1 PF07690.11 KNZ75154.1 - 1.8e-24 86.0 36.1 2.9e-24 85.4 25.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1752 PF08550.5 KNZ75155.1 - 9.3e-08 31.5 3.7 1.8e-07 30.6 2.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) BUD22 PF09073.5 KNZ75155.1 - 0.025 13.6 0.4 0.036 13.1 0.3 1.1 1 0 0 1 1 1 0 BUD22 MARCKS PF02063.12 KNZ75155.1 - 0.068 13.0 0.0 0.091 12.5 0.0 1.1 1 0 0 1 1 1 0 MARCKS family Cwf_Cwc_15 PF04889.7 KNZ75155.1 - 2.1 7.9 4.8 3.1 7.4 3.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pyr_redox_3 PF13738.1 KNZ75156.1 - 4.6e-19 69.2 0.0 9.8e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KNZ75156.1 - 1.2e-14 53.4 0.0 4.3e-14 51.6 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KNZ75156.1 - 5.3e-12 45.5 0.0 1.2e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KNZ75156.1 - 9.2e-05 22.2 0.3 0.00083 19.1 0.0 2.6 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 KNZ75156.1 - 0.0036 16.2 0.0 0.088 11.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KNZ75156.1 - 0.0076 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KNZ75156.1 - 0.11 10.9 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 KNZ75156.1 - 0.15 11.5 0.0 0.37 10.2 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 KNZ75157.1 - 1.2e-21 76.8 24.2 1.4e-20 73.3 18.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily SyrA PF11089.3 KNZ75157.1 - 1.8 8.4 9.1 0.26 11.0 1.4 2.9 2 0 0 2 2 2 0 Exopolysaccharide production repressor PACT_coil_coil PF10495.4 KNZ75158.1 - 3.6e-12 46.0 0.1 2.6e-11 43.3 0.1 2.6 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CDP-OH_P_transf PF01066.16 KNZ75159.1 - 0.1 12.8 2.6 0.17 12.2 1.8 1.7 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase BTB PF00651.26 KNZ75160.1 - 0.0041 17.1 0.1 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KNZ75161.1 - 6.2e-09 35.8 0.0 1.7e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Ribosomal_L5_C PF00673.16 KNZ75162.1 - 1.8e-22 78.8 0.0 2.6e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KNZ75162.1 - 3e-20 71.7 0.1 8.7e-20 70.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 NMO PF03060.10 KNZ75163.1 - 2e-66 224.3 1.2 2.5e-66 224.1 0.8 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KNZ75163.1 - 0.00046 19.1 0.2 0.023 13.5 0.1 2.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KNZ75163.1 - 0.0015 17.4 1.7 0.0023 16.8 1.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF1515 PF07439.6 KNZ75164.1 - 0.2 11.4 17.5 0.42 10.4 2.4 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1515) CALCOCO1 PF07888.6 KNZ75164.1 - 1.2 7.2 28.4 2 6.6 1.5 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Sulfatase_C PF14707.1 KNZ75164.1 - 4.1 7.7 6.3 4.8 7.4 0.1 3.6 2 1 3 5 5 5 0 C-terminal region of aryl-sulfatase NPV_P10 PF05531.7 KNZ75164.1 - 4.5 7.5 11.5 13 6.0 3.1 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TSC22 PF01166.13 KNZ75164.1 - 4.8 7.2 0.0 4.8 7.2 0.0 5.0 4 1 1 6 6 6 0 TSC-22/dip/bun family Atg14 PF10186.4 KNZ75165.1 - 1.4e-07 30.7 5.3 2.1e-07 30.2 3.7 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Ax_dynein_light PF10211.4 KNZ75165.1 - 0.0033 17.2 2.9 0.21 11.3 0.2 2.1 2 0 0 2 2 2 1 Axonemal dynein light chain TMCO5 PF14992.1 KNZ75165.1 - 0.014 14.5 4.9 0.018 14.1 3.4 1.1 1 0 0 1 1 1 0 TMCO5 family zf-C3HC4_2 PF13923.1 KNZ75165.1 - 0.023 14.7 2.7 0.048 13.6 1.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4407 PF14362.1 KNZ75165.1 - 0.025 13.5 2.3 0.039 12.9 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C3HC4_4 PF15227.1 KNZ75165.1 - 0.055 13.3 2.3 0.11 12.3 1.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KNZ75165.1 - 0.066 13.0 1.1 0.14 12.0 0.8 1.5 1 0 0 1 1 1 0 Ring finger domain Occludin_ELL PF07303.8 KNZ75165.1 - 0.077 13.7 8.3 1.3 9.7 1.8 2.2 2 0 0 2 2 2 0 Occludin homology domain DUF1048 PF06304.6 KNZ75165.1 - 0.1 12.9 0.8 0.22 11.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1048) Fib_alpha PF08702.5 KNZ75165.1 - 0.1 12.7 8.9 0.21 11.7 0.7 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family IncA PF04156.9 KNZ75165.1 - 0.11 12.1 7.8 0.22 11.0 5.4 1.5 1 1 0 1 1 1 0 IncA protein Alpha-mann_mid PF09261.6 KNZ75165.1 - 0.17 12.1 1.3 0.34 11.1 0.9 1.7 1 1 0 1 1 1 0 Alpha mannosidase, middle domain CENP-F_leu_zip PF10473.4 KNZ75165.1 - 0.29 11.0 8.5 6.1 6.6 5.0 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C3HC4_3 PF13920.1 KNZ75165.1 - 0.32 10.6 2.9 0.54 9.9 1.2 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GAS PF13851.1 KNZ75165.1 - 0.4 9.8 11.7 3.5 6.7 0.1 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Histone_HNS PF00816.16 KNZ75165.1 - 0.49 10.9 0.0 0.49 10.9 0.0 2.6 2 1 0 2 2 1 0 H-NS histone family KIAA1430 PF13879.1 KNZ75165.1 - 0.49 10.8 7.7 0.16 12.3 2.0 2.0 2 0 0 2 2 2 0 KIAA1430 homologue Fmp27_WPPW PF10359.4 KNZ75165.1 - 0.67 8.3 9.3 0.16 10.3 3.2 1.8 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain HlyD PF00529.15 KNZ75165.1 - 0.93 8.7 11.1 1.2 8.4 7.7 1.1 1 0 0 1 1 1 0 HlyD family secretion protein TPR_MLP1_2 PF07926.7 KNZ75165.1 - 1.1 8.9 12.5 0.22 11.2 1.0 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein MRP-L46 PF11788.3 KNZ75165.1 - 1.2 9.8 5.4 4.3 8.0 3.8 2.1 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 NAM-associated PF14303.1 KNZ75165.1 - 1.5 9.1 8.2 0.29 11.4 2.8 1.7 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Pox_A_type_inc PF04508.7 KNZ75165.1 - 1.8 8.5 9.9 0.74 9.7 0.5 2.9 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4557 PF15101.1 KNZ75165.1 - 1.8 8.3 6.5 0.33 10.7 0.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4557) HALZ PF02183.13 KNZ75165.1 - 1.8 8.3 8.0 5 6.9 0.2 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.10 KNZ75165.1 - 1.9 8.0 10.6 3.4 7.2 0.3 3.3 3 1 1 4 4 3 0 Septum formation initiator TipAS PF07739.8 KNZ75165.1 - 2.6 8.3 7.5 1.1 9.6 0.1 2.2 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain V_ATPase_I PF01496.14 KNZ75165.1 - 2.7 5.7 4.2 5.9 4.6 2.9 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 KNZ75165.1 - 7.7 5.4 13.1 8.6 5.3 5.3 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF342 PF03961.8 KNZ75165.1 - 8.8 4.6 9.5 2.2 6.6 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) WLM PF08325.5 KNZ75166.1 - 7.2e-35 120.5 0.3 1.3e-34 119.7 0.2 1.4 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.18 KNZ75166.1 - 4e-07 29.3 0.0 1.6e-06 27.4 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin family Peptidase_MA_2 PF13485.1 KNZ75166.1 - 0.0033 17.4 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily DNA_pol_delta_4 PF04081.8 KNZ75167.1 - 6.3e-21 74.9 1.6 1.9e-20 73.4 0.0 2.0 1 1 1 2 2 2 1 DNA polymerase delta, subunit 4 FAD_binding_3 PF01494.14 KNZ75169.1 - 2.1e-90 303.3 0.0 2.8e-90 302.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KNZ75169.1 - 7.3e-27 94.0 0.0 1.3e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 KNZ75169.1 - 1.6e-05 23.5 0.6 2.5e-05 22.9 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 KNZ75169.1 - 2.9e-05 23.9 0.5 0.00018 21.4 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KNZ75169.1 - 4.2e-05 22.5 0.7 6.5e-05 21.9 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KNZ75169.1 - 9.8e-05 22.3 0.7 0.0032 17.3 0.5 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNZ75169.1 - 0.00039 20.2 0.1 0.0062 16.3 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 KNZ75169.1 - 0.00043 19.8 0.2 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 KNZ75169.1 - 0.00054 18.9 0.1 0.0012 17.7 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KNZ75169.1 - 0.00072 18.7 0.1 0.0015 17.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 KNZ75169.1 - 0.0066 15.1 0.0 0.011 14.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 KNZ75169.1 - 0.0072 16.3 0.2 0.015 15.3 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KNZ75169.1 - 0.01 14.9 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KNZ75169.1 - 0.011 14.6 0.1 0.017 14.0 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.13 KNZ75169.1 - 0.014 15.3 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.7 KNZ75169.1 - 0.02 13.7 0.9 0.037 12.9 0.7 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 KNZ75169.1 - 0.031 14.6 0.1 0.22 11.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KNZ75169.1 - 0.038 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding UCH PF00443.24 KNZ75170.1 - 8.1e-65 218.5 0.0 1.3e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNZ75170.1 - 2e-29 103.0 0.0 4.1e-29 101.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 KNZ75170.1 - 7.7e-05 23.0 0.0 0.00021 21.5 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain zf-RanBP PF00641.13 KNZ75170.1 - 1.1 8.3 4.0 0.48 9.5 0.3 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others ADIP PF11559.3 KNZ75171.1 - 9.2e-22 77.5 3.9 9.2e-22 77.5 2.7 3.5 3 1 1 4 4 4 2 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 KNZ75171.1 - 4.6 6.9 24.8 0.35 10.6 3.6 3.9 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein zf-HC5HC2H_2 PF13832.1 KNZ75172.1 - 1.9e-16 60.0 3.0 1.9e-16 60.0 2.1 4.3 4 1 0 4 4 4 2 PHD-zinc-finger like domain PHD PF00628.24 KNZ75172.1 - 5.8e-14 51.5 52.4 2.1e-09 36.9 6.6 6.0 6 0 0 6 6 6 3 PHD-finger zf-HC5HC2H PF13771.1 KNZ75172.1 - 4.2e-13 49.2 3.0 4.2e-13 49.2 2.1 4.6 4 1 0 4 4 4 2 PHD-like zinc-binding domain BAH PF01426.13 KNZ75172.1 - 1.5e-11 44.0 0.0 3.3e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 BAH domain PHD_2 PF13831.1 KNZ75172.1 - 0.0012 18.0 2.7 0.0012 18.0 1.9 6.1 6 0 0 6 6 6 3 PHD-finger C1_1 PF00130.17 KNZ75172.1 - 0.0019 17.8 3.8 0.0019 17.8 2.6 6.3 6 1 1 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.14 KNZ75172.1 - 0.05 13.2 2.6 0.13 11.9 1.8 1.8 1 0 0 1 1 1 0 AT hook motif Prok-RING_1 PF14446.1 KNZ75172.1 - 0.21 11.3 35.1 0.014 15.1 3.5 5.4 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 HATPase_c PF02518.21 KNZ75173.1 - 3.7e-25 87.7 0.0 7.3e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KNZ75173.1 - 1.4e-17 63.7 0.0 1.1e-09 38.2 0.0 2.8 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c_3 PF13589.1 KNZ75173.1 - 0.036 13.7 0.0 0.094 12.3 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ran_BP1 PF00638.13 KNZ75174.1 - 8.7e-16 58.0 0.0 1.5e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Glycos_transf_2 PF00535.21 KNZ75175.1 - 3.2e-22 78.9 0.0 4.1e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KNZ75175.1 - 1.3e-09 38.2 0.0 4.5e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KNZ75175.1 - 0.018 14.1 0.0 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 KNZ75175.1 - 0.048 13.9 0.0 0.082 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 CBM_1 PF00734.13 KNZ75177.1 - 6.1e-07 28.9 10.8 6.1e-07 28.9 7.5 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain DUF1604 PF07713.8 KNZ75178.1 - 3.9e-38 129.1 0.9 3.9e-38 129.1 0.6 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KNZ75178.1 - 4.1e-07 29.6 1.2 3.8e-05 23.3 0.3 2.8 2 0 0 2 2 2 2 G-patch domain WD40 PF00400.27 KNZ75179.1 - 3.1e-17 61.7 5.6 1.5e-08 34.2 0.0 5.3 5 1 0 5 5 5 4 WD domain, G-beta repeat DNA_pol_A_exo1 PF01612.15 KNZ75180.1 - 1.4e-06 27.9 0.1 4.3e-06 26.3 0.1 1.7 1 1 0 1 1 1 1 3'-5' exonuclease Amidase PF01425.16 KNZ75181.1 - 2.6e-67 227.5 5.0 3.3e-67 227.2 3.5 1.1 1 0 0 1 1 1 1 Amidase RhoGEF PF00621.15 KNZ75187.1 - 3.2e-65 219.3 0.3 1.2e-33 116.4 0.1 2.5 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.17 KNZ75187.1 - 7.3e-61 205.9 0.0 1.1e-60 205.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 KNZ75187.1 - 5.8e-17 61.8 0.0 1.6e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KNZ75187.1 - 1.5e-06 28.3 0.0 3.8e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 PH domain DEP PF00610.16 KNZ75187.1 - 0.00012 21.6 0.0 0.0003 20.4 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) F-box PF00646.28 KNZ75188.1 - 4.8e-06 26.0 0.2 1.3e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KNZ75188.1 - 0.0042 16.7 0.1 0.016 14.9 0.1 2.0 2 0 0 2 2 2 1 F-box-like BIR PF00653.16 KNZ75189.1 - 6.7e-32 109.7 1.6 1.7e-16 60.3 0.1 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 KNZ75189.1 - 3.1e-05 23.7 0.0 0.044 13.5 0.0 2.6 2 0 0 2 2 2 2 C3HC zinc finger-like IN_DBD_C PF00552.16 KNZ75189.1 - 0.048 13.1 0.1 6.8 6.2 0.0 2.6 2 0 0 2 2 2 0 Integrase DNA binding domain WAPL PF07814.8 KNZ75190.1 - 3.6e-12 45.7 0.0 5.5e-11 41.7 0.0 2.5 2 1 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin rRNA_proc-arch PF13234.1 KNZ75191.1 - 1.3e-82 277.0 0.0 1.9e-82 276.4 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KNZ75191.1 - 1.8e-54 183.7 0.0 3.8e-54 182.6 0.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KNZ75191.1 - 2.3e-21 76.0 0.0 5.5e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ75191.1 - 3.7e-07 29.8 0.0 8.7e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ75191.1 - 0.0029 17.4 0.0 0.045 13.5 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 KNZ75191.1 - 0.012 14.5 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 KNZ75191.1 - 0.029 14.0 0.6 0.79 9.3 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase PhoH PF02562.11 KNZ75191.1 - 0.093 11.9 0.0 0.74 9.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AA_permease PF00324.16 KNZ75192.1 - 1.9e-119 399.1 37.6 2.3e-119 398.8 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KNZ75192.1 - 2.3e-35 121.9 40.3 3.1e-35 121.5 28.0 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2363 PF10155.4 KNZ75192.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) Methyltransf_23 PF13489.1 KNZ75193.1 - 2.3e-13 50.1 0.0 4.2e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ75193.1 - 9.6e-11 42.0 0.0 2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ75193.1 - 4.1e-09 36.8 0.0 9.3e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ75193.1 - 5.3e-09 36.3 0.0 9.7e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ75193.1 - 7.6e-09 35.3 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ75193.1 - 2.2e-08 34.6 0.0 4.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ75193.1 - 7e-05 22.8 0.0 0.00027 20.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 KNZ75193.1 - 0.0017 18.0 0.0 0.051 13.1 0.0 2.2 1 1 1 2 2 2 1 Hypothetical methyltransferase MTS PF05175.9 KNZ75193.1 - 0.009 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 KNZ75193.1 - 0.015 14.2 0.0 0.03 13.2 0.0 1.5 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.13 KNZ75193.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF3419 PF11899.3 KNZ75193.1 - 0.02 13.5 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.1 KNZ75193.1 - 0.097 13.5 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Topo_Zn_Ribbon PF08272.6 KNZ75193.1 - 0.12 11.6 0.2 0.36 10.2 0.1 1.8 1 1 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RhoGEF PF00621.15 KNZ75194.1 - 3.1e-65 219.4 0.2 7.4e-32 110.6 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.17 KNZ75194.1 - 7.6e-60 202.6 0.0 1.2e-59 202.0 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 KNZ75194.1 - 9.8e-20 70.8 0.0 2.7e-19 69.4 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KNZ75194.1 - 1.1e-05 25.5 0.0 2.9e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 PH domain DEP PF00610.16 KNZ75194.1 - 0.00011 21.9 0.0 0.00023 20.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ECH_C PF13766.1 KNZ75196.1 - 0.094 12.8 0.2 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region RNase_H PF00075.19 KNZ75199.1 - 0.0011 19.2 0.0 0.0018 18.6 0.0 1.4 2 0 0 2 2 2 1 RNase H Herpes_Helicase PF02689.9 KNZ75201.1 - 4.6e-06 24.6 0.0 4.9e-06 24.6 0.0 1.0 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 KNZ75202.1 - 1e-33 116.8 0.0 1.1e-33 116.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Chitin_synth_1 PF01644.12 KNZ75203.1 - 5.9e-87 289.5 0.1 1.1e-86 288.6 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KNZ75203.1 - 1.6e-31 107.8 0.1 3.2e-31 106.8 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KNZ75203.1 - 6.1e-25 87.6 0.4 6.2e-19 67.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KNZ75203.1 - 4.7e-07 29.7 2.6 4.7e-07 29.7 1.8 2.3 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KNZ75203.1 - 1.6e-05 24.7 0.0 4.9e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 adh_short PF00106.20 KNZ75204.1 - 1.3e-26 93.5 0.0 1.6e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ75204.1 - 2.8e-12 46.9 0.0 4.2e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ75204.1 - 1.6e-10 40.9 0.0 2.7e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KNZ75204.1 - 3.1e-06 26.2 0.0 4.2e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KNZ75204.1 - 6.1e-06 25.8 0.0 2.5e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ75204.1 - 0.0011 19.0 0.1 0.0016 18.5 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KNZ75204.1 - 0.015 14.5 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.7 KNZ75204.1 - 0.015 14.2 0.4 0.028 13.3 0.3 1.7 1 1 0 1 1 1 0 Male sterility protein DapB_N PF01113.15 KNZ75204.1 - 0.058 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 KNZ75204.1 - 0.11 11.1 0.1 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PIF1 PF05970.9 KNZ75205.1 - 1.6e-54 185.2 0.8 1.2e-32 113.2 0.0 2.0 1 1 1 2 2 2 2 PIF1-like helicase Viral_helicase1 PF01443.13 KNZ75205.1 - 0.01 15.3 0.2 0.047 13.2 0.1 2.1 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KNZ75205.1 - 0.036 14.2 0.5 0.43 10.7 0.1 2.7 1 1 1 2 2 2 0 RNA helicase PhoH PF02562.11 KNZ75205.1 - 0.045 12.9 0.0 0.18 10.9 0.0 1.9 1 1 1 2 2 2 0 PhoH-like protein AAA_30 PF13604.1 KNZ75205.1 - 0.078 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NMO PF03060.10 KNZ75210.1 - 4.1e-44 151.0 3.0 8.3e-43 146.7 2.1 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 KNZ75210.1 - 3.7e-05 22.7 0.7 5.5e-05 22.1 0.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KNZ75210.1 - 0.0045 15.9 1.1 0.022 13.6 0.1 1.9 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KNZ75210.1 - 0.023 13.9 0.6 0.088 12.0 0.1 2.1 2 1 1 3 3 3 0 Histidine biosynthesis protein IMPDH PF00478.20 KNZ75210.1 - 0.053 12.4 0.1 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KNZ75210.1 - 0.078 12.0 0.2 0.14 11.1 0.1 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 KNZ75210.1 - 0.088 11.7 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase ADH_zinc_N PF00107.21 KNZ75211.1 - 1.5e-21 76.3 0.0 2.4e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KNZ75211.1 - 4.4e-06 27.6 0.0 9.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KNZ75211.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Retrotrans_gag PF03732.12 KNZ75212.1 - 0.00077 19.4 0.1 0.0016 18.4 0.0 1.7 1 1 1 2 2 2 1 Retrotransposon gag protein 7TM_GPCR_Srab PF10292.4 KNZ75213.1 - 0.3 9.7 7.2 0.31 9.6 4.3 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor PIF1 PF05970.9 KNZ75214.1 - 2.4e-39 135.3 0.1 2.6e-39 135.2 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ75214.1 - 0.025 14.1 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF2863 PF11062.3 KNZ75214.1 - 0.097 10.7 0.0 0.11 10.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) Exo_endo_phos PF03372.18 KNZ75215.1 - 1.3e-09 38.4 0.0 1.8e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KNZ75215.1 - 6.2e-05 22.5 0.2 0.00014 21.4 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase AfsA PF03756.8 KNZ75216.1 - 0.057 13.1 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain zf-RVT PF13966.1 KNZ75217.1 - 0.0017 18.6 2.2 0.0026 18.0 1.5 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase L31 PF09784.4 KNZ75217.1 - 0.12 12.4 0.4 0.16 12.0 0.2 1.4 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 p450 PF00067.17 KNZ75218.1 - 3.1e-83 279.8 0.0 3.7e-83 279.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_15 PF00723.16 KNZ75219.1 - 2.2e-41 141.9 0.0 1.9e-22 79.4 0.0 3.6 3 1 0 3 3 3 3 Glycosyl hydrolases family 15 FAD_binding_4 PF01565.18 KNZ75220.1 - 2.6e-11 43.1 0.2 1.2e-10 41.0 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain ALO PF04030.9 KNZ75220.1 - 5.8e-08 32.6 0.3 2.5e-07 30.5 0.2 2.2 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Clat_adaptor_s PF01217.15 KNZ75221.1 - 6e-49 165.4 1.7 8e-49 165.0 1.2 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain F-box-like PF12937.2 KNZ75222.1 - 0.0039 16.8 0.1 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ75222.1 - 0.045 13.4 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 F-box domain CsbD PF05532.7 KNZ75223.1 - 1e-10 41.1 6.5 2.2e-10 40.0 1.7 2.1 1 1 1 2 2 2 2 CsbD-like GMC_oxred_N PF00732.14 KNZ75224.1 - 2.2e-57 194.4 0.0 3e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ75224.1 - 6.1e-34 117.3 0.0 1.1e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KNZ75224.1 - 0.0007 18.6 0.0 0.0014 17.6 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KNZ75224.1 - 0.07 13.1 0.1 0.23 11.5 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Zn_clus PF00172.13 KNZ75225.1 - 0.27 11.1 8.3 1.7 8.6 0.4 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KNZ75227.1 - 3e-31 108.5 13.8 1.5e-24 86.3 6.9 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KNZ75227.1 - 1.4e-20 73.3 11.7 8.9e-17 60.8 5.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily ThylakoidFormat PF11264.3 KNZ75229.1 - 0.036 13.6 0.1 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 Thylakoid formation protein DUF2235 PF09994.4 KNZ75231.1 - 1.7e-78 263.8 0.0 2.5e-78 263.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KNZ75231.1 - 0.027 14.2 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family COG6 PF06419.6 KNZ75233.1 - 3.3e-141 471.4 2.9 3.3e-141 471.4 2.0 1.9 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 Paramyxo_NS_C PF02725.9 KNZ75233.1 - 0.0054 16.3 0.1 0.018 14.6 0.1 1.9 1 0 0 1 1 1 1 Non-structural protein C TMEM223 PF14640.1 KNZ75233.1 - 0.044 13.7 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 223 Prenyltransf PF01255.14 KNZ75234.1 - 4.9e-72 241.6 0.0 6.3e-72 241.3 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase AP_endonuc_2 PF01261.19 KNZ75234.1 - 0.027 13.7 0.1 0.095 11.9 0.0 1.8 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel CBP PF12192.3 KNZ75236.1 - 0.0026 17.6 4.3 0.0026 17.6 3.0 2.0 2 0 0 2 2 2 1 Fungal calcium binding protein Asp_protease_2 PF13650.1 KNZ75237.1 - 0.0047 17.4 0.0 0.0071 16.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KNZ75237.1 - 0.05 13.4 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease TMEM171 PF15471.1 KNZ75238.1 - 0.12 11.1 0.7 0.17 10.6 0.5 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Chromo PF00385.19 KNZ75239.1 - 2.9e-10 39.6 0.2 4.8e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KNZ75239.1 - 0.0055 16.3 0.1 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF2235 PF09994.4 KNZ75241.1 - 1.2e-79 267.6 0.1 1.7e-79 267.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KNZ75241.1 - 0.03 14.0 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.6 KNZ75241.1 - 0.086 12.5 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal MFS_1 PF07690.11 KNZ75242.1 - 7.2e-18 64.4 29.2 7.2e-18 64.4 20.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ75242.1 - 5.1e-06 25.3 9.8 5.1e-06 25.3 6.8 3.0 1 1 1 3 3 3 1 Sugar (and other) transporter DUF2269 PF10027.4 KNZ75242.1 - 0.014 15.2 0.4 0.014 15.2 0.3 2.5 3 1 0 3 3 3 0 Predicted integral membrane protein (DUF2269) TRIQK PF15168.1 KNZ75242.1 - 1 9.3 3.0 1.3 9.0 0.2 2.4 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Ras PF00071.17 KNZ75243.1 - 3.8e-51 172.6 0.0 4.4e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ75243.1 - 2.2e-15 57.2 0.0 2.8e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ75243.1 - 1e-07 31.3 0.0 1.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KNZ75243.1 - 0.0012 18.1 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KNZ75243.1 - 0.042 13.8 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase PyrI_C PF02748.10 KNZ75243.1 - 0.045 13.1 0.2 0.15 11.5 0.1 1.9 1 1 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Gtr1_RagA PF04670.7 KNZ75243.1 - 0.046 12.8 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KNZ75243.1 - 0.098 12.1 0.1 2.8 7.4 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3445 PF11927.3 KNZ75244.1 - 4.5e-70 235.8 0.0 5.7e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) FAD_binding_3 PF01494.14 KNZ75246.1 - 2.5e-16 59.7 0.0 5.9e-08 32.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 KNZ75246.1 - 0.00011 21.2 0.6 0.0046 15.9 0.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KNZ75246.1 - 0.00015 21.7 0.2 0.00036 20.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KNZ75246.1 - 0.00032 20.5 0.2 0.0055 16.4 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KNZ75246.1 - 0.01 14.8 0.0 0.12 11.2 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KNZ75246.1 - 0.016 14.2 0.3 0.031 13.3 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KNZ75246.1 - 0.026 14.3 0.3 0.044 13.6 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KNZ75246.1 - 0.19 10.5 0.0 1.4 7.6 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Kelch_4 PF13418.1 KNZ75247.1 - 5.3e-18 64.5 7.9 0.0014 18.3 0.0 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KNZ75247.1 - 1.3e-15 56.7 14.2 3.1e-06 27.1 0.0 6.8 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 KNZ75247.1 - 6e-13 48.5 17.0 0.00022 21.2 0.0 6.8 6 2 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KNZ75247.1 - 4e-10 39.4 6.7 0.12 12.3 0.1 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 KNZ75247.1 - 6.7e-10 38.3 7.2 0.0002 20.9 0.0 5.9 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 KNZ75247.1 - 9.8e-10 37.8 3.8 0.05 13.1 0.0 6.2 6 0 0 6 6 6 2 Kelch motif zf-MYND PF01753.13 KNZ75247.1 - 0.00066 19.4 7.8 0.0015 18.3 5.4 1.6 1 0 0 1 1 1 1 MYND finger TPR_8 PF13181.1 KNZ75247.1 - 0.065 13.0 0.1 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ75247.1 - 0.17 12.2 0.1 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat HEAT_2 PF13646.1 KNZ75248.1 - 1.5e-12 47.6 9.5 0.14 12.4 0.0 7.7 6 1 1 7 7 7 4 HEAT repeats Adaptin_N PF01602.15 KNZ75248.1 - 5.1e-07 28.3 4.6 0.0012 17.2 0.0 3.2 3 1 0 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.1 KNZ75248.1 - 1.6e-05 25.2 16.4 0.015 15.7 0.2 7.8 6 1 2 8 8 8 2 HEAT-like repeat HEAT PF02985.17 KNZ75248.1 - 0.00011 21.9 15.6 2.4 8.4 0.0 9.2 11 0 0 11 11 11 2 HEAT repeat Arm PF00514.18 KNZ75248.1 - 0.0041 16.9 0.9 0.056 13.2 0.1 3.2 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat TctB PF07331.6 KNZ75249.1 - 1.3 8.6 9.0 0.2 11.3 3.2 1.8 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF1191 PF06697.7 KNZ75251.1 - 3e-05 23.0 0.4 4.6e-05 22.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Rifin_STEVOR PF02009.11 KNZ75251.1 - 0.0022 17.6 2.1 0.0033 17.0 1.5 1.2 1 0 0 1 1 1 1 Rifin/stevor family DUF1180 PF06679.7 KNZ75251.1 - 0.0031 17.4 7.2 0.0031 17.4 5.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) TMEM154 PF15102.1 KNZ75251.1 - 0.043 13.5 2.9 0.17 11.5 2.0 2.0 1 1 0 1 1 1 0 TMEM154 protein family Glycophorin_A PF01102.13 KNZ75251.1 - 0.045 13.5 7.3 0.13 12.0 5.0 1.8 1 1 0 1 1 1 0 Glycophorin A SKG6 PF08693.5 KNZ75251.1 - 0.12 11.7 0.9 0.26 10.6 0.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Macoilin PF09726.4 KNZ75251.1 - 2.4 6.3 7.8 3 6.0 5.4 1.2 1 0 0 1 1 1 0 Transmembrane protein DSPc PF00782.15 KNZ75252.1 - 9.9e-32 109.3 0.0 1.2e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KNZ75252.1 - 0.0015 18.6 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 KNZ75252.1 - 0.0042 16.0 0.0 0.0042 16.0 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 KNZ75252.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Myotub-related PF06602.9 KNZ75252.1 - 0.08 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Glyco_hydro_61 PF03443.9 KNZ75253.1 - 1.6e-42 145.8 0.0 1.9e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAD_binding_4 PF07993.7 KNZ75254.1 - 6.6e-27 94.0 0.0 1.1e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KNZ75254.1 - 2.4e-12 45.9 0.1 7.1e-11 41.1 0.1 2.6 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KNZ75254.1 - 5.4e-10 39.1 0.0 1.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ75254.1 - 0.0094 15.9 0.0 0.035 14.1 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding ABA_GPCR PF12430.3 KNZ75254.1 - 0.052 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor PP-binding PF00550.20 KNZ75254.1 - 0.053 13.7 0.1 0.27 11.5 0.0 2.3 1 1 0 1 1 1 0 Phosphopantetheine attachment site Aldo_ket_red PF00248.16 KNZ75255.1 - 6.6e-42 143.2 0.0 2.2e-41 141.5 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 KNZ75256.1 - 6.8e-27 94.0 40.1 7.6e-25 87.3 22.0 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KNZ75256.1 - 0.002 18.0 0.7 0.002 18.0 0.5 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) BAG PF02179.11 KNZ75257.1 - 6.6e-05 22.9 1.0 0.0002 21.4 0.7 1.8 1 0 0 1 1 1 1 BAG domain PBP PF01161.15 KNZ75258.1 - 9.8e-13 48.1 0.0 1.1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3846 PF12957.2 KNZ75258.1 - 0.065 12.9 0.1 0.52 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) Pkinase_Tyr PF07714.12 KNZ75259.1 - 1.3e-70 237.4 0.0 2e-32 112.3 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.20 KNZ75259.1 - 1.8e-66 223.9 0.0 1.6e-38 132.3 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Kinase-like PF14531.1 KNZ75259.1 - 4.6e-05 22.5 0.0 0.03 13.2 0.0 3.2 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 KNZ75259.1 - 7.7e-05 21.8 0.0 2.1 7.3 0.0 3.3 3 0 0 3 3 3 3 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KNZ75259.1 - 0.00086 18.6 0.4 6.5 6.0 0.0 4.3 4 1 0 4 4 4 2 RIO1 family TraI PF07057.6 KNZ75259.1 - 0.082 12.9 0.0 0.33 10.9 0.0 2.0 1 0 0 1 1 1 0 DNA helicase TraI DUF3806 PF12713.2 KNZ75259.1 - 0.082 12.3 0.0 2.4 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3806) APH PF01636.18 KNZ75259.1 - 0.16 11.6 4.8 0.77 9.4 0.1 3.8 6 0 0 6 6 6 0 Phosphotransferase enzyme family DUF4139 PF13598.1 KNZ75260.1 - 2.3e-84 283.4 0.0 3.6e-84 282.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KNZ75260.1 - 1.9e-21 76.4 7.8 7.1e-21 74.6 0.3 3.3 2 1 1 3 3 3 1 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 KNZ75260.1 - 0.042 13.4 2.4 0.077 12.5 1.7 1.4 1 0 0 1 1 1 0 IncA protein PMEI PF04043.10 KNZ75260.1 - 0.071 13.0 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Prominin PF05478.6 KNZ75260.1 - 0.074 10.5 0.4 0.14 9.6 0.2 1.3 1 1 0 1 1 1 0 Prominin Tropomyosin_1 PF12718.2 KNZ75260.1 - 0.096 12.5 6.9 0.16 11.8 4.8 1.3 1 0 0 1 1 1 0 Tropomyosin like Seryl_tRNA_N PF02403.17 KNZ75260.1 - 0.11 12.4 2.2 0.26 11.3 1.5 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prefoldin_2 PF01920.15 KNZ75260.1 - 0.13 12.0 10.2 1.3 8.8 0.9 2.3 1 1 0 2 2 2 0 Prefoldin subunit Cortex-I_coil PF09304.5 KNZ75260.1 - 0.14 12.2 7.0 0.59 10.2 0.4 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil APG6 PF04111.7 KNZ75260.1 - 0.17 10.9 4.6 0.28 10.2 3.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 KNZ75260.1 - 0.46 10.3 8.6 3.9 7.3 1.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cu-oxidase PF00394.17 KNZ75261.1 - 2.2e-43 147.9 0.1 4e-41 140.5 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KNZ75261.1 - 3.2e-42 142.9 0.7 2.1e-39 133.8 0.2 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KNZ75261.1 - 1.7e-35 121.5 7.6 8.3e-32 109.5 0.3 3.9 3 1 0 3 3 3 3 Multicopper oxidase Chromo PF00385.19 KNZ75263.1 - 2.3e-16 59.1 0.2 2.6e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4139 PF13598.1 KNZ75264.1 - 4.3e-39 134.6 0.0 3.8e-38 131.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KNZ75264.1 - 5.1e-17 62.2 0.0 1.8e-15 57.2 0.0 2.3 1 1 1 2 2 2 1 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.15 KNZ75264.1 - 0.068 12.9 5.8 2.8 7.7 0.7 2.4 2 0 0 2 2 2 0 Prefoldin subunit BLOC1_2 PF10046.4 KNZ75264.1 - 0.12 12.5 3.1 0.27 11.4 2.1 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.2 KNZ75264.1 - 0.12 12.1 2.8 0.2 11.5 1.9 1.2 1 0 0 1 1 1 0 Tropomyosin like PBP PF01161.15 KNZ75266.1 - 7.3e-14 51.8 0.0 9.1e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein WD40 PF00400.27 KNZ75267.1 - 1.1e-158 510.1 77.2 2.7e-13 49.2 0.2 15.8 15 1 0 15 15 15 14 WD domain, G-beta repeat PD40 PF07676.7 KNZ75267.1 - 2.2e-14 52.7 8.2 4 7.2 0.1 12.8 13 0 0 13 13 13 2 WD40-like Beta Propeller Repeat NACHT PF05729.7 KNZ75267.1 - 6.4e-13 48.6 0.0 1.4e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.11 KNZ75267.1 - 8e-13 47.4 15.9 0.0011 17.3 0.4 6.0 3 2 4 7 7 7 5 Cytochrome D1 heme domain AAA_16 PF13191.1 KNZ75267.1 - 7.2e-05 22.8 0.0 0.00037 20.5 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 KNZ75267.1 - 0.0016 18.1 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 KNZ75267.1 - 0.013 15.6 2.2 0.037 14.1 0.0 2.9 3 1 0 3 3 3 0 AAA domain AAA_17 PF13207.1 KNZ75267.1 - 0.019 15.8 1.4 0.14 12.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KNZ75267.1 - 0.02 15.0 0.1 0.11 12.7 0.1 2.3 1 1 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 KNZ75267.1 - 0.02 14.4 0.1 0.095 12.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.1 KNZ75267.1 - 0.027 13.8 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KNZ75267.1 - 0.066 13.1 0.4 13 5.6 0.0 4.3 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.1 KNZ75267.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 KNZ75267.1 - 0.19 10.8 0.1 1.5 7.8 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin UPF0147 PF03685.8 KNZ75270.1 - 0.062 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Chromo PF00385.19 KNZ75272.1 - 4.3e-17 61.5 0.1 5.1e-17 61.2 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CALCOCO1 PF07888.6 KNZ75273.1 - 0.014 13.7 0.0 0.015 13.6 0.0 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DNA_pol3_delt_C PF14840.1 KNZ75273.1 - 0.085 12.9 0.5 0.18 11.8 0.1 1.6 1 1 1 2 2 2 0 Processivity clamp loader gamma complex DNA pol III C-term PaREP1 PF05942.6 KNZ75273.1 - 7.9 6.3 7.8 1.6 8.6 1.4 2.1 1 1 0 2 2 2 0 Archaeal PaREP1/PaREP8 family PCNA_C PF02747.10 KNZ75274.1 - 2e-14 53.5 0.1 2.8e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain TolA PF06519.6 KNZ75274.1 - 0.00033 20.5 0.4 0.00058 19.7 0.3 1.4 1 0 0 1 1 1 1 TolA C-terminal Hus1 PF04005.7 KNZ75274.1 - 0.012 14.6 0.1 0.021 13.7 0.0 1.4 1 1 0 1 1 1 0 Hus1-like protein SART-1 PF03343.8 KNZ75274.1 - 0.012 13.9 2.7 0.015 13.6 1.9 1.1 1 0 0 1 1 1 0 SART-1 family PCNA_N PF00705.13 KNZ75274.1 - 0.013 14.9 0.4 0.026 14.0 0.0 1.6 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain WD40 PF00400.27 KNZ75275.1 - 5e-168 539.7 73.3 2.7e-13 49.2 0.2 14.5 14 0 0 14 14 14 14 WD domain, G-beta repeat PD40 PF07676.7 KNZ75275.1 - 4.2e-17 61.3 7.2 5.5 6.7 0.0 13.8 14 0 0 14 14 14 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 KNZ75275.1 - 3.3e-12 45.3 16.7 0.0012 17.2 0.4 5.9 2 1 5 7 7 7 4 Cytochrome D1 heme domain NACHT PF05729.7 KNZ75275.1 - 2.2e-11 43.7 0.1 4.9e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KNZ75275.1 - 0.00038 20.4 0.5 0.0025 17.8 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KNZ75275.1 - 0.0059 16.7 0.0 0.025 14.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 KNZ75275.1 - 0.0062 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 KNZ75275.1 - 0.014 15.5 0.5 0.085 13.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.1 KNZ75275.1 - 0.024 14.0 0.3 0.12 11.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KNZ75275.1 - 0.027 14.7 9.0 5.4 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KNZ75275.1 - 0.029 13.9 0.0 0.1 12.1 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KNZ75275.1 - 0.034 13.2 0.0 0.69 8.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 KNZ75275.1 - 0.049 13.9 0.5 0.27 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KNZ75275.1 - 0.059 13.5 1.0 0.64 10.2 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KNZ75275.1 - 0.077 12.7 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Tricorn_C1 PF14684.1 KNZ75275.1 - 0.085 12.7 0.0 0.33 10.8 0.0 2.0 1 0 0 1 1 1 0 Tricorn protease C1 domain AAA_17 PF13207.1 KNZ75275.1 - 0.12 13.1 1.2 1.9 9.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KNZ75275.1 - 0.89 9.4 4.5 2.2 8.1 0.0 3.9 4 0 0 4 4 3 0 AAA domain RNase_H PF00075.19 KNZ75276.1 - 1.6e-09 38.2 0.0 2.8e-09 37.4 0.0 1.4 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.1 KNZ75276.1 - 0.019 14.7 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase-like DUF4248 PF14053.1 KNZ75277.1 - 0.092 12.3 0.3 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) Retrotrans_gag PF03732.12 KNZ75280.1 - 0.028 14.4 0.9 0.047 13.7 0.1 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein TIR PF01582.15 KNZ75280.1 - 0.053 12.9 0.1 0.13 11.6 0.1 1.7 1 1 0 1 1 1 0 TIR domain PS_Dcarbxylase PF02666.10 KNZ75281.1 - 7.8e-55 185.3 0.0 1.2e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 KNZ75281.1 - 3.3e-32 110.1 0.3 2.2e-16 59.4 0.1 3.0 3 0 0 3 3 3 2 C2 domain CEP76-C2 PF15627.1 KNZ75281.1 - 0.038 13.4 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 CEP76 C2 domain DUF4430 PF14478.1 KNZ75282.1 - 7.7e-06 25.8 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4430) IDO PF01231.13 KNZ75284.1 - 2.1e-108 362.5 0.0 2.4e-108 362.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 KNZ75284.1 - 0.02 13.4 0.0 2.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) CBM_3 PF00942.13 KNZ75285.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Cellulose binding domain G-alpha PF00503.15 KNZ75286.1 - 9.2e-95 317.5 0.0 1.2e-94 317.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KNZ75286.1 - 5.8e-06 25.6 0.5 1.4 8.1 0.0 3.6 4 0 0 4 4 4 3 ADP-ribosylation factor family DUF815 PF05673.8 KNZ75286.1 - 0.0017 17.3 0.0 0.015 14.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 KNZ75286.1 - 0.0019 17.6 0.0 0.0043 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Asp_protease_2 PF13650.1 KNZ75287.1 - 9.9e-05 22.7 0.0 0.00014 22.2 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 KNZ75287.1 - 0.0016 18.3 0.1 0.0017 18.2 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease NAD_binding_4 PF07993.7 KNZ75290.1 - 4.8e-34 117.3 0.0 7.3e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KNZ75290.1 - 2.5e-27 95.3 0.0 4.7e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KNZ75290.1 - 0.00035 20.0 0.0 0.00079 18.9 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KNZ75290.1 - 0.0034 17.6 0.0 0.011 15.9 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KNZ75290.1 - 0.015 15.2 0.1 0.072 13.0 0.0 2.2 2 1 0 2 2 2 0 short chain dehydrogenase VWA PF00092.23 KNZ75291.1 - 9.8e-06 25.4 0.0 1.2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KNZ75291.1 - 1.7e-05 24.7 0.0 2.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 KNZ75291.1 - 0.00028 21.0 0.1 0.00036 20.6 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Copine PF07002.11 KNZ75291.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 1 0 1 1 1 0 Copine RNA12 PF10443.4 KNZ75292.1 - 6.7e-110 367.5 0.0 1.5e-109 366.3 0.0 1.6 1 1 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 KNZ75292.1 - 1.7e-05 24.6 0.0 8.2e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 KNZ75292.1 - 3.2e-05 23.9 0.5 0.00063 19.7 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KNZ75292.1 - 0.0016 18.5 0.0 0.044 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KNZ75292.1 - 0.014 14.8 0.0 0.044 13.2 0.0 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RRM_1 PF00076.17 KNZ75292.1 - 0.024 14.2 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_33 PF13671.1 KNZ75292.1 - 0.04 13.7 0.2 0.11 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KNZ75292.1 - 0.074 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KNZ75292.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RRM_5 PF13893.1 KNZ75292.1 - 0.23 11.3 0.0 0.53 10.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF974 PF06159.8 KNZ75293.1 - 2.3e-63 213.9 0.0 3e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) V-ATPase_H_N PF03224.9 KNZ75294.1 - 7.4e-86 288.0 1.1 7.4e-86 288.0 0.7 1.7 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KNZ75294.1 - 3.5e-43 146.2 3.7 8.9e-43 144.9 0.1 2.8 3 0 0 3 3 3 1 V-ATPase subunit H Arm_2 PF04826.8 KNZ75294.1 - 2.7e-05 23.4 0.2 0.001 18.2 0.0 2.4 1 1 1 2 2 2 1 Armadillo-like HEAT_2 PF13646.1 KNZ75294.1 - 0.0004 20.6 1.9 0.083 13.1 0.0 3.3 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.17 KNZ75294.1 - 0.0006 19.6 3.4 0.16 12.1 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat DUF1786 PF08735.5 KNZ75294.1 - 0.082 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) MRP-L46 PF11788.3 KNZ75295.1 - 4.2e-20 72.4 0.1 1.1e-19 71.1 0.1 1.7 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KNZ75295.1 - 4.3e-09 36.1 0.0 8.2e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Endonuclease_NS PF01223.18 KNZ75296.1 - 7.5e-53 179.2 0.0 1e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease R3H PF01424.17 KNZ75297.1 - 1.7e-13 50.0 0.1 4.2e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 KNZ75297.1 - 5.8e-08 32.5 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KNZ75297.1 - 1.4e-07 31.0 0.0 3.1e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ75297.1 - 5.4e-05 22.9 0.2 0.00012 21.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.21 KNZ75298.1 - 5.9e-42 142.4 0.0 7.4e-42 142.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KNZ75298.1 - 0.00014 21.7 0.0 0.00019 21.2 0.0 1.4 1 1 0 1 1 1 1 RWD domain EF-hand_4 PF12763.2 KNZ75299.1 - 6.4e-32 109.3 0.0 3.7e-13 49.1 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KNZ75299.1 - 1.2e-08 34.9 0.4 0.00012 22.1 0.0 4.0 3 1 0 3 3 3 1 EF-hand domain pair UBA PF00627.26 KNZ75299.1 - 1.8e-06 27.5 0.1 3.8e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 KNZ75299.1 - 3.7e-05 22.7 2.3 0.18 11.1 0.0 5.5 6 0 0 6 6 6 1 EF hand EF-hand_8 PF13833.1 KNZ75299.1 - 0.012 15.2 0.2 9.1 5.9 0.0 4.0 4 0 0 4 4 4 0 EF-hand domain pair WEMBL PF05701.6 KNZ75299.1 - 0.027 12.9 35.8 0.042 12.3 24.8 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light EF-hand_6 PF13405.1 KNZ75299.1 - 0.029 14.2 3.4 23 5.2 0.0 4.8 6 0 0 6 6 5 0 EF-hand domain UBA_3 PF09288.5 KNZ75299.1 - 0.038 13.5 0.1 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain IncA PF04156.9 KNZ75299.1 - 0.21 11.1 28.1 3.1 7.3 9.4 2.4 1 1 1 2 2 2 0 IncA protein AAA_13 PF13166.1 KNZ75299.1 - 0.24 9.8 20.8 0.39 9.1 14.4 1.2 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 KNZ75299.1 - 0.71 9.7 40.0 0.026 14.3 14.7 3.5 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 KNZ75299.1 - 0.79 6.9 27.6 1.1 6.5 19.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.6 KNZ75299.1 - 1.8 7.9 18.0 0.1 11.9 2.8 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 KNZ75299.1 - 2 7.5 12.3 0.58 9.2 3.2 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 KNZ75299.1 - 3.5 7.7 15.2 0.37 10.8 3.1 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Fez1 PF06818.10 KNZ75299.1 - 3.7 7.5 25.0 3.8 7.4 7.3 2.4 1 1 1 2 2 2 0 Fez1 Occludin_ELL PF07303.8 KNZ75299.1 - 5.1 7.8 16.1 1.6 9.5 2.5 3.5 1 1 2 3 3 3 0 Occludin homology domain Atg14 PF10186.4 KNZ75299.1 - 7.8 5.3 29.9 13 4.6 7.3 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CALCOCO1 PF07888.6 KNZ75299.1 - 8.3 4.5 22.4 15 3.7 15.5 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2420 PF10336.4 KNZ75300.1 - 6.7e-05 22.4 0.0 0.00017 21.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) 5_nucleotid_C PF02872.13 KNZ75302.1 - 6.1e-25 88.0 0.0 1.2e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KNZ75302.1 - 6.6e-11 41.9 0.0 1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3321 PF11968.3 KNZ75303.1 - 3.5e-35 121.6 0.0 4.5e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Tetraspannin PF00335.15 KNZ75305.1 - 3.6e-07 29.6 14.3 4.8e-07 29.2 9.9 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF4233 PF14017.1 KNZ75305.1 - 9 6.2 15.5 3.8 7.4 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) MBF1 PF08523.5 KNZ75306.1 - 2e-21 75.7 2.5 4.5e-21 74.6 1.7 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KNZ75306.1 - 1e-12 47.6 0.1 1.9e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 KNZ75306.1 - 4.1e-06 26.9 0.0 7.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 KNZ75306.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Tubulin PF00091.20 KNZ75307.1 - 2.5e-74 249.7 0.0 4.6e-74 248.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KNZ75307.1 - 7.8e-48 161.6 0.4 1.3e-47 160.9 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KNZ75307.1 - 0.00039 20.4 0.0 0.0017 18.4 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KNZ75307.1 - 0.009 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF3658 PF12395.3 KNZ75307.1 - 0.078 12.5 0.1 16 5.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function LGFP PF08310.6 KNZ75307.1 - 0.12 12.0 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 LGFP repeat Alpha-amylase PF00128.19 KNZ75308.1 - 2e-60 204.8 0.3 2.8e-60 204.3 0.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KNZ75308.1 - 9e-14 51.3 0.0 1.8e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Sugar_tr PF00083.19 KNZ75309.1 - 7.3e-74 248.9 21.7 9e-74 248.6 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ75309.1 - 5.4e-16 58.2 32.0 5.4e-16 58.2 22.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KNZ75309.1 - 7.4e-05 21.3 25.1 0.0066 14.8 2.3 3.5 2 2 1 3 3 3 3 MFS/sugar transport protein Not1 PF04054.10 KNZ75310.1 - 8e-115 383.7 0.0 1.6e-114 382.7 0.0 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KNZ75310.1 - 5.9e-52 175.2 0.6 1.3e-51 174.1 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) FdhE PF04216.7 KNZ75310.1 - 0.51 10.0 0.1 1.1 8.9 0.1 1.5 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Abhydrolase_5 PF12695.2 KNZ75311.1 - 6.1e-15 55.2 0.2 4.1e-14 52.5 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family PDEase_II PF02112.10 KNZ75311.1 - 7.6e-13 48.0 0.0 1.1e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Abhydrolase_6 PF12697.2 KNZ75311.1 - 1.7e-12 47.7 5.6 4.3e-12 46.4 2.3 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ75311.1 - 1e-10 41.1 0.0 1.7e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KNZ75311.1 - 5.4e-05 22.7 0.0 0.099 12.0 0.0 2.9 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Esterase PF00756.15 KNZ75311.1 - 9.7e-05 21.9 0.2 0.00019 20.9 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 KNZ75311.1 - 0.00011 21.8 1.3 0.00092 18.8 0.1 2.7 3 1 1 4 4 4 1 alpha/beta hydrolase fold Lactamase_B_2 PF12706.2 KNZ75311.1 - 0.00028 20.4 0.1 0.00085 18.9 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KNZ75311.1 - 0.004 16.8 0.0 0.019 14.5 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Tannase PF07519.6 KNZ75311.1 - 0.016 13.9 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase Abhydrolase_3 PF07859.8 KNZ75311.1 - 0.028 14.0 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KNZ75311.1 - 0.18 11.1 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) 3HBOH PF10605.4 KNZ75311.1 - 0.4 8.6 0.0 0.6 8.1 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) WD40 PF00400.27 KNZ75312.1 - 7.5e-47 155.6 3.4 2.6e-11 42.9 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.7 KNZ75312.1 - 7.6e-40 136.3 18.8 1.1e-36 126.1 0.7 4.3 4 0 0 4 4 4 2 Striatin family TMA7 PF09072.5 KNZ75312.1 - 1.2e-14 54.5 16.7 4.3e-14 52.7 11.6 2.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Nucleoporin_N PF08801.6 KNZ75312.1 - 0.00027 19.8 0.1 0.6 8.7 0.0 2.8 2 2 1 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 KNZ75312.1 - 0.0052 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 PQQ-like domain SNN_linker PF09050.5 KNZ75312.1 - 9.4 5.8 9.6 15 5.2 3.1 2.8 2 0 0 2 2 2 0 Stannin unstructured linker RNA_pol_Rpc82 PF05645.8 KNZ75314.1 - 6.3e-20 71.8 3.4 1.3e-16 60.9 2.5 2.9 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 KNZ75314.1 - 1.3e-17 63.3 0.9 3.7e-12 45.9 0.2 3.8 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KNZ75314.1 - 8.8e-12 44.4 0.0 4e-10 39.1 0.0 3.2 2 0 0 2 2 2 1 TFIIE alpha subunit Metallophos PF00149.23 KNZ75315.1 - 3.4e-08 33.1 2.8 1.6e-07 30.9 2.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KNZ75315.1 - 1.2e-06 28.3 0.0 2.7e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_C3 PF00548.15 KNZ75315.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) SPT16 PF08644.6 KNZ75316.1 - 7.2e-54 181.7 0.2 3.8e-53 179.4 0.1 2.4 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KNZ75316.1 - 2.5e-40 137.6 0.0 8e-40 136.0 0.0 2.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 KNZ75316.1 - 2.1e-21 76.4 0.0 3.7e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 KNZ75316.1 - 5.2e-20 71.2 0.1 1.5e-19 69.7 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF3956 PF13104.1 KNZ75316.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Mannosyl_trans2 PF04188.8 KNZ75317.1 - 6.8e-55 186.7 26.9 1.5e-54 185.5 18.7 1.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) Uds1 PF15456.1 KNZ75318.1 - 0.044 13.7 0.6 0.076 13.0 0.4 1.3 1 0 0 1 1 1 0 Up-regulated During Septation TMF_DNA_bd PF12329.3 KNZ75318.1 - 0.32 10.8 6.4 0.62 9.9 4.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DEAD PF00270.24 KNZ75320.1 - 1.1e-17 64.1 0.0 1.9e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ75320.1 - 4e-11 42.6 0.1 5.9e-10 38.8 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ75320.1 - 5.5e-07 29.5 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1998 PF09369.5 KNZ75320.1 - 6.5e-07 29.8 5.3 2e-06 28.2 3.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Pkinase PF00069.20 KNZ75321.1 - 5.7e-21 74.8 0.0 9e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ75321.1 - 2.7e-12 46.3 0.0 7.5e-12 44.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 KNZ75321.1 - 0.026 14.5 0.0 0.077 13.1 0.0 1.9 1 0 0 1 1 1 0 HEAT repeat NAD_binding_2 PF03446.10 KNZ75322.1 - 3.5e-36 124.4 0.0 5e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KNZ75322.1 - 9.7e-32 109.5 0.0 2e-31 108.5 0.0 1.5 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KNZ75322.1 - 0.00062 20.1 0.0 0.002 18.5 0.0 2.0 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Coiled PF05710.7 KNZ75322.1 - 0.32 11.4 5.9 0.39 11.2 3.5 1.6 1 1 0 1 1 1 0 Coiled coil Cytochrom_B561 PF03188.11 KNZ75324.1 - 1.5e-08 34.5 9.2 1.5e-08 34.5 6.4 2.2 2 1 1 3 3 3 2 Eukaryotic cytochrome b561 Sec7 PF01369.15 KNZ75325.1 - 9.9e-64 214.5 0.3 1.7e-63 213.7 0.2 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KNZ75325.1 - 3.9e-19 68.6 5.5 5e-19 68.3 0.3 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KNZ75325.1 - 0.0031 16.9 1.9 0.54 9.8 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Proteasome PF00227.21 KNZ75326.1 - 7.5e-60 201.4 0.0 1.1e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KNZ75326.1 - 1.3e-14 53.2 0.1 1.3e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Orthopox_B11R PF07033.6 KNZ75326.1 - 0.28 10.7 2.7 6.1 6.3 0.4 2.9 3 0 0 3 3 3 0 Orthopoxvirus B11R protein Peptidase_C78 PF07910.8 KNZ75327.1 - 9.9e-48 162.1 0.0 1.8e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.14 KNZ75327.1 - 0.036 13.1 0.2 0.12 11.5 0.0 1.9 3 0 0 3 3 3 0 Peptidase family C54 EFG_C PF00679.19 KNZ75327.1 - 0.046 13.5 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 Elongation factor G C-terminus MAT1 PF06391.8 KNZ75328.1 - 3.1e-47 160.7 15.2 3.8e-47 160.4 10.5 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 KNZ75328.1 - 2.3e-05 24.0 6.9 6.2e-05 22.6 4.9 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KNZ75328.1 - 2.7e-05 23.7 5.0 6.1e-05 22.5 3.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNZ75328.1 - 4.7e-05 22.9 6.7 0.00015 21.3 4.9 1.7 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ75328.1 - 0.0004 20.3 6.9 0.0014 18.5 5.1 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ75328.1 - 0.00062 19.5 7.8 0.0017 18.1 5.7 1.6 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KNZ75328.1 - 0.016 15.2 1.9 0.029 14.4 1.3 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 KNZ75328.1 - 0.02 14.5 3.5 0.16 11.5 0.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain YdjO PF14169.1 KNZ75328.1 - 0.27 10.7 2.5 2.8 7.4 0.0 2.5 1 1 1 2 2 2 0 Cold-inducible protein YdjO zf-C3HC4_4 PF15227.1 KNZ75328.1 - 3.7 7.5 7.6 15 5.5 5.5 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING LigB PF02900.13 KNZ75329.1 - 5e-44 150.3 0.0 6.6e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Pkinase PF00069.20 KNZ75330.1 - 2.6e-63 213.6 0.0 3.1e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ75330.1 - 6.1e-30 104.1 0.0 7.5e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ75330.1 - 0.00083 18.3 0.0 0.0024 16.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KNZ75330.1 - 0.035 13.8 0.1 1.3 8.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.27 KNZ75331.1 - 1.4e-19 69.1 6.3 1.6e-05 24.6 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat FerA PF08165.6 KNZ75331.1 - 0.087 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 FerA (NUC095) domain Nucleoporin_N PF08801.6 KNZ75331.1 - 0.16 10.6 2.3 5.1 5.7 0.0 2.9 2 1 1 3 3 3 0 Nup133 N terminal like NMO PF03060.10 KNZ75332.1 - 1e-62 212.2 2.3 4.3e-62 210.1 1.6 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 KNZ75332.1 - 0.00038 19.4 3.5 0.00059 18.7 2.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KNZ75332.1 - 0.02 13.7 1.1 0.02 13.7 0.8 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Cyto_heme_lyase PF01265.12 KNZ75333.1 - 1.2e-76 257.6 0.1 1.9e-76 257.0 0.1 1.2 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Brix PF04427.13 KNZ75334.1 - 2.6e-45 154.4 0.0 3.6e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.8 KNZ75334.1 - 0.41 10.4 21.9 0.57 10.0 15.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 KNZ75334.1 - 0.57 8.1 20.0 0.71 7.8 13.9 1.3 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.7 KNZ75334.1 - 1.4 6.9 16.9 1.9 6.4 11.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SlyX PF04102.7 KNZ75335.1 - 0.004 17.5 0.0 0.0091 16.3 0.0 1.6 1 0 0 1 1 1 1 SlyX TPR_11 PF13414.1 KNZ75336.1 - 4.4e-07 29.4 6.5 1.1 8.9 0.0 6.5 6 0 0 6 6 6 2 TPR repeat TPR_12 PF13424.1 KNZ75336.1 - 7.1e-06 25.8 8.3 0.42 10.5 0.1 6.6 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ75336.1 - 4.9e-05 22.9 12.0 0.75 9.8 0.0 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ75336.1 - 0.00014 22.1 3.8 2.8 8.3 0.0 5.8 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ75336.1 - 0.00072 19.9 12.6 48 4.9 0.0 9.5 9 2 2 11 11 11 0 Tetratricopeptide repeat Suf PF05843.9 KNZ75336.1 - 0.00073 19.3 12.6 0.0016 18.2 0.8 5.1 4 1 1 5 5 5 1 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.7 KNZ75336.1 - 0.0022 17.7 5.8 1.2 8.9 0.2 5.1 4 2 2 6 6 6 1 Mad3/BUB1 homology region 1 DALR_1 PF05746.10 KNZ75336.1 - 0.24 11.3 3.7 0.58 10.1 0.0 3.1 3 0 0 3 3 3 0 DALR anticodon binding domain PPTA PF01239.17 KNZ75337.1 - 3.4e-45 149.5 19.2 1.7e-09 36.6 0.0 6.6 8 0 0 8 8 8 5 Protein prenyltransferase alpha subunit repeat Lzipper-MIP1 PF14389.1 KNZ75337.1 - 0.028 14.5 0.5 0.083 12.9 0.3 1.8 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 TPR_17 PF13431.1 KNZ75337.1 - 0.16 12.2 1.1 32 5.0 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Piwi PF02171.12 KNZ75338.1 - 6.6e-70 235.4 0.0 1.1e-69 234.7 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KNZ75338.1 - 2.3e-07 30.0 0.0 5.6e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) VASP_tetra PF08776.6 KNZ75338.1 - 0.0014 17.8 0.1 0.0014 17.8 0.1 2.0 2 0 0 2 2 2 1 VASP tetramerisation domain Got1 PF04178.7 KNZ75339.1 - 7.9e-17 61.4 22.0 1.3e-16 60.7 15.3 1.4 1 1 0 1 1 1 1 Got1/Sft2-like family Lactamase_B PF00753.22 KNZ75340.1 - 3.1e-18 66.1 0.8 4.9e-18 65.4 0.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KNZ75340.1 - 0.0064 16.0 0.1 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 KNZ75340.1 - 0.087 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF1517 PF07466.6 KNZ75341.1 - 0.0089 15.0 0.8 0.0089 15.0 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1517) Adeno_E3_CR2 PF02439.10 KNZ75341.1 - 0.016 14.7 0.2 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.15 KNZ75341.1 - 0.04 13.5 0.6 0.064 12.9 0.4 1.2 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.1 KNZ75341.1 - 0.073 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.7 KNZ75341.1 - 0.082 12.5 0.6 1.7 8.2 0.2 2.1 2 0 0 2 2 2 0 CD34/Podocalyxin family Herpes_gE PF02480.11 KNZ75341.1 - 0.25 9.5 0.0 0.25 9.5 0.0 2.2 2 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF4381 PF14316.1 KNZ75341.1 - 0.33 11.0 0.0 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) SRP54 PF00448.17 KNZ75342.1 - 1.7e-45 154.9 0.1 1.1e-44 152.2 0.1 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 KNZ75342.1 - 5.5e-42 144.0 4.7 3.5e-41 141.4 3.2 2.0 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 KNZ75342.1 - 8.2e-07 29.0 0.0 3e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 KNZ75342.1 - 2.2e-06 27.2 0.0 5.2e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 KNZ75342.1 - 8.2e-05 21.5 0.1 0.00021 20.1 0.1 1.6 1 1 0 1 1 1 1 ArgK protein BP28CT PF08146.7 KNZ75342.1 - 0.0015 18.2 0.1 0.003 17.3 0.1 1.4 1 0 0 1 1 1 1 BP28CT (NUC211) domain MobB PF03205.9 KNZ75342.1 - 0.0033 17.1 0.0 0.0096 15.6 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KNZ75342.1 - 0.0048 17.0 0.1 0.085 13.0 0.0 2.9 2 1 0 3 3 3 1 AAA domain AAA_30 PF13604.1 KNZ75342.1 - 0.02 14.4 0.0 0.069 12.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.10 KNZ75342.1 - 0.033 13.2 0.3 1.8 7.4 0.0 2.3 1 1 1 2 2 2 0 Anion-transporting ATPase ETF PF01012.16 KNZ75342.1 - 0.034 13.8 0.1 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 Electron transfer flavoprotein domain Fer4_NifH PF00142.13 KNZ75342.1 - 0.066 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Cyclin_N PF00134.18 KNZ75343.1 - 6.8e-09 35.3 0.0 1.7e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 Cyclin, N-terminal domain Trans_reg_C PF00486.23 KNZ75344.1 - 0.008 16.0 0.3 0.017 15.0 0.2 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal TMF_TATA_bd PF12325.3 KNZ75344.1 - 0.11 12.2 0.6 0.19 11.4 0.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding AAA_32 PF13654.1 KNZ75344.1 - 0.12 11.0 0.3 0.16 10.5 0.2 1.1 1 0 0 1 1 1 0 AAA domain PC-Esterase PF13839.1 KNZ75345.1 - 3.4e-10 40.2 0.9 1.9e-09 37.7 0.7 2.2 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p SOR_SNZ PF01680.12 KNZ75346.1 - 8.6e-114 378.2 4.3 1.2e-113 377.7 3.0 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 KNZ75346.1 - 1.5e-09 37.2 5.3 3.8e-07 29.4 0.2 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 KNZ75346.1 - 5.1e-05 22.2 0.3 0.1 11.3 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.10 KNZ75346.1 - 0.0032 16.6 4.9 0.014 14.5 0.1 2.3 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 KNZ75346.1 - 0.0048 16.1 0.6 0.16 11.2 0.0 2.6 2 1 1 3 3 3 1 Histidine biosynthesis protein NanE PF04131.9 KNZ75346.1 - 0.0065 15.4 0.4 0.3 10.0 0.0 2.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 KNZ75346.1 - 0.01 14.9 0.1 0.073 12.1 0.0 2.2 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase PEP_mutase PF13714.1 KNZ75346.1 - 0.055 12.6 1.6 0.13 11.4 0.3 2.1 2 1 1 3 3 3 0 Phosphoenolpyruvate phosphomutase DUF2984 PF11203.3 KNZ75346.1 - 0.12 12.4 0.1 0.34 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2984) Img2 PF05046.9 KNZ75347.1 - 8.7e-21 73.9 0.0 1.1e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Piwi PF02171.12 KNZ75349.1 - 3.6e-55 187.0 0.0 1.1e-54 185.4 0.0 1.7 2 0 0 2 2 2 1 Piwi domain DUF1785 PF08699.5 KNZ75349.1 - 2.7e-15 55.4 0.0 6.3e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KNZ75349.1 - 2.4e-11 43.0 0.0 4.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Ras PF00071.17 KNZ75350.1 - 6.1e-47 159.0 0.6 7.3e-47 158.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ75350.1 - 2.5e-13 50.5 0.0 4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ75350.1 - 5.2e-13 48.6 0.1 6.2e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KNZ75350.1 - 1.8e-06 27.4 0.1 2.5e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KNZ75350.1 - 0.01 15.0 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Zn_clus PF00172.13 KNZ75352.1 - 1.7e-06 27.8 5.1 1.7e-06 27.8 3.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop16 PF09420.5 KNZ75353.1 - 9e-34 116.9 0.0 1.1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 QCR10 PF09796.4 KNZ75354.1 - 2.4e-16 59.1 0.0 2.7e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) HAD_2 PF13419.1 KNZ75355.1 - 9.5e-16 58.5 0.0 2.4e-15 57.2 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KNZ75355.1 - 2.6e-05 23.8 0.0 4.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KNZ75355.1 - 0.14 12.5 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase EF-hand_1 PF00036.27 KNZ75356.1 - 2.8e-21 73.1 0.2 3.6e-05 22.7 0.0 4.9 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 KNZ75356.1 - 7.3e-19 65.9 0.3 6.6e-05 22.4 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 KNZ75356.1 - 9.4e-18 64.1 0.0 3.3e-08 33.5 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KNZ75356.1 - 3.5e-16 57.7 1.8 0.0003 19.9 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KNZ75356.1 - 5.2e-11 41.9 2.4 6.3e-06 25.7 0.1 4.2 4 1 1 5 5 5 2 EF-hand domain pair Toprim_2 PF13155.1 KNZ75356.1 - 0.0091 16.3 0.0 1.7 9.0 0.0 2.6 1 1 0 2 2 2 1 Toprim-like EF-hand_9 PF14658.1 KNZ75356.1 - 0.0091 15.8 0.0 22 5.0 0.0 3.5 2 1 1 3 3 3 0 EF-hand domain EF-hand_2 PF09068.6 KNZ75356.1 - 0.11 12.5 0.0 16 5.6 0.0 3.2 3 1 1 4 4 4 0 EF hand BAF1_ABF1 PF04684.8 KNZ75356.1 - 0.11 11.3 3.2 0.14 11.0 2.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor AMP-binding PF00501.23 KNZ75357.1 - 9.3e-69 231.8 0.0 1.3e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.11 KNZ75358.1 - 7.9e-20 70.8 27.3 1.2e-19 70.2 18.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 KNZ75358.1 - 0.072 11.5 23.8 0.021 13.3 5.5 3.3 3 1 0 3 3 3 0 Vacuole effluxer Atg22 like Peptidase_M24 PF00557.19 KNZ75360.1 - 1e-41 142.8 0.0 1.4e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KNZ75360.1 - 6.9e-05 23.3 0.0 0.00012 22.6 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain 2OG-FeII_Oxy_2 PF13532.1 KNZ75361.1 - 2.4e-22 79.7 0.0 3.3e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UBA PF00627.26 KNZ75361.1 - 0.0037 17.0 0.1 0.0068 16.2 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 KNZ75361.1 - 0.066 12.7 0.2 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 CUE domain Peptidase_M13_N PF05649.8 KNZ75362.1 - 1e-98 330.9 0.0 1.4e-98 330.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KNZ75362.1 - 2.6e-51 173.7 0.0 4.6e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Mucin PF01456.12 KNZ75362.1 - 0.00046 19.9 10.5 0.00081 19.1 7.3 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein IGPD PF00475.13 KNZ75363.1 - 3.7e-57 192.2 0.6 4.8e-57 191.9 0.2 1.3 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase SbcCD_C PF13558.1 KNZ75363.1 - 0.11 12.4 0.1 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit zf-Mss51 PF13824.1 KNZ75364.1 - 6.3e-22 77.1 15.1 1.2e-21 76.2 10.4 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Lar_restr_allev PF14354.1 KNZ75364.1 - 0.022 15.0 6.4 0.049 13.9 4.4 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar Integrin_alpha PF00357.15 KNZ75364.1 - 0.14 11.9 0.8 0.32 10.8 0.5 1.6 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region zf-MYND PF01753.13 KNZ75364.1 - 6.9 6.6 11.0 15 5.5 7.7 1.6 1 0 0 1 1 1 0 MYND finger WD40 PF00400.27 KNZ75365.1 - 8.4e-49 161.7 17.6 8.5e-14 50.8 0.2 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 KNZ75365.1 - 6.7e-06 24.5 2.4 0.16 10.1 0.0 4.0 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KNZ75365.1 - 0.00023 20.0 3.6 0.017 13.8 0.2 3.9 1 1 2 3 3 3 2 Nup133 N terminal like Hira PF07569.6 KNZ75365.1 - 0.00052 19.2 0.3 1.6 7.8 0.0 3.1 3 1 1 4 4 4 2 TUP1-like enhancer of split Cytochrom_D1 PF02239.11 KNZ75365.1 - 0.0045 15.3 0.1 0.49 8.6 0.0 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain DUF3312 PF11768.3 KNZ75365.1 - 0.0054 15.0 0.0 0.0096 14.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Gmad1 PF10647.4 KNZ75365.1 - 0.017 14.5 0.0 0.097 12.0 0.0 2.2 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Chromo PF00385.19 KNZ75366.1 - 2e-12 46.5 1.0 2.5e-12 46.2 0.7 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KNZ75366.1 - 0.075 12.9 0.4 0.098 12.5 0.3 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DUF647 PF04884.9 KNZ75367.1 - 1.6e-63 214.2 0.0 4.2e-63 212.8 0.0 1.6 1 1 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Sp38 PF07354.7 KNZ75369.1 - 9.2 4.8 8.2 9.8 4.7 5.7 1.0 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) Chromo PF00385.19 KNZ75371.1 - 2.9e-16 58.8 0.0 3.3e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RPN7 PF10602.4 KNZ75373.1 - 9.4e-42 142.3 0.0 1.5e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KNZ75373.1 - 7.3e-18 64.8 0.2 2.9e-17 62.8 0.1 2.1 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KNZ75373.1 - 0.00014 21.6 0.1 0.00039 20.2 0.1 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DDRGK PF09756.4 KNZ75373.1 - 0.058 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 DDRGK domain TPR_2 PF07719.12 KNZ75373.1 - 0.062 13.2 0.2 1.2 9.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ADH_zinc_N PF00107.21 KNZ75374.1 - 4.3e-23 81.2 0.0 7.2e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KNZ75374.1 - 2.9e-05 24.9 0.1 5.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 KNZ75376.1 - 1.7e-34 118.5 0.3 3e-34 117.7 0.2 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 KNZ75376.1 - 0.00048 19.2 0.2 0.0013 17.7 0.1 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 KNZ75376.1 - 0.00059 19.5 0.0 0.0015 18.2 0.0 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KNZ75376.1 - 0.0077 16.4 0.1 0.017 15.3 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.19 KNZ75376.1 - 0.019 13.8 0.4 0.032 13.1 0.1 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Glyco_hydro_17 PF00332.13 KNZ75376.1 - 0.036 13.0 0.3 0.71 8.8 0.0 2.4 2 1 1 3 3 3 0 Glycosyl hydrolases family 17 FAD_binding_3 PF01494.14 KNZ75376.1 - 0.15 11.0 0.3 0.24 10.4 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain NUDIX PF00293.23 KNZ75377.1 - 1.5e-05 24.6 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Peroxidase_2 PF01328.12 KNZ75378.1 - 1.6e-20 73.0 0.0 1.9e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Ribonuclease_T2 PF00445.13 KNZ75378.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease T2 family F-box-like PF12937.2 KNZ75379.1 - 0.00011 21.9 0.0 0.00026 20.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like Cys_Met_Meta_PP PF01053.15 KNZ75380.1 - 6.1e-129 429.6 0.0 6.7e-129 429.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KNZ75380.1 - 7.4e-12 44.8 0.0 1.3e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KNZ75380.1 - 1.9e-10 40.3 0.1 6e-10 38.7 0.1 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KNZ75380.1 - 5.8e-08 31.8 0.0 8.8e-08 31.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KNZ75380.1 - 3.9e-07 29.5 0.0 7e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 KNZ75380.1 - 0.00072 17.9 0.4 0.0016 16.8 0.3 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase TNV_CP PF03898.8 KNZ75380.1 - 0.1 11.6 0.3 0.16 10.9 0.2 1.2 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein SLA_LP_auto_ag PF05889.8 KNZ75380.1 - 0.13 10.7 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) F-box-like PF12937.2 KNZ75381.1 - 0.00011 21.8 0.1 0.0004 20.0 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KNZ75381.1 - 0.0041 16.7 2.8 0.017 14.7 0.1 3.4 4 0 0 4 4 4 1 F-box domain SIR2 PF02146.12 KNZ75382.1 - 7.7e-31 107.1 0.0 2e-29 102.5 0.0 2.6 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 KNZ75382.1 - 0.0041 16.8 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4_10 PF13237.1 KNZ75382.1 - 0.052 13.3 2.1 0.1 12.4 1.4 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF1272 PF06906.6 KNZ75382.1 - 1.2 9.0 4.0 0.76 9.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Abhydrolase_6 PF12697.2 KNZ75383.1 - 2.8e-07 30.6 0.0 4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ75383.1 - 0.00076 19.2 0.0 0.0025 17.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ75383.1 - 0.0024 17.4 0.0 0.02 14.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KNZ75383.1 - 0.0026 17.6 0.0 0.0084 15.9 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein FSH1 PF03959.8 KNZ75383.1 - 0.034 13.5 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) TraK PF06586.6 KNZ75385.1 - 0.12 11.5 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 TraK protein TPT PF03151.11 KNZ75386.1 - 1.3e-06 28.1 12.5 1.3e-06 28.1 8.7 3.2 2 2 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KNZ75386.1 - 0.00017 21.5 12.0 0.00017 21.5 8.3 2.3 2 1 0 2 2 2 2 EamA-like transporter family Carb_anhydrase PF00194.16 KNZ75388.1 - 5.1e-19 68.2 0.1 1.3e-18 66.9 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Chitin_synth_2 PF03142.10 KNZ75388.1 - 0.031 12.6 0.0 0.041 12.2 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase PAPS_reduct PF01507.14 KNZ75389.1 - 2.3e-31 108.9 0.0 2.8e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Epimerase PF01370.16 KNZ75390.1 - 4.5e-51 173.5 0.0 6.1e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KNZ75390.1 - 1.3e-06 27.5 0.0 9e-05 21.4 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KNZ75390.1 - 1.7e-06 27.1 0.8 0.00023 20.1 0.6 3.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KNZ75390.1 - 0.0009 18.0 0.0 0.0014 17.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KNZ75390.1 - 0.0071 15.3 0.1 0.21 10.4 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 KNZ75391.1 - 1.4e-67 227.5 0.0 1.8e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KNZ75391.1 - 1.1e-05 24.5 0.0 2.3e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KNZ75391.1 - 0.013 14.3 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 KNZ75391.1 - 0.08 12.1 0.0 0.2 10.8 0.0 1.8 2 1 0 2 2 2 0 NmrA-like family Epimerase_Csub PF13950.1 KNZ75391.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit NAD_binding_10 PF13460.1 KNZ75391.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding SUZ PF12752.2 KNZ75392.1 - 4.3e-14 52.7 1.4 4.3e-14 52.7 1.0 2.5 2 1 1 3 3 3 1 SUZ domain Peptidase_M20 PF01546.23 KNZ75393.1 - 1.9e-30 105.8 0.0 3.2e-30 105.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KNZ75393.1 - 5.7e-12 45.3 0.0 9.6e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KNZ75393.1 - 0.084 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 MIP PF00230.15 KNZ75395.1 - 2.5e-53 180.8 10.6 2.8e-53 180.7 7.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein PAP2 PF01569.16 KNZ75395.1 - 0.011 15.4 1.9 0.011 15.4 1.3 2.4 1 1 0 2 2 2 0 PAP2 superfamily DUF4596 PF15363.1 KNZ75395.1 - 0.083 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) EamA PF00892.15 KNZ75395.1 - 2 8.4 10.6 0.64 10.0 2.9 2.6 1 1 1 2 2 2 0 EamA-like transporter family p450 PF00067.17 KNZ75397.1 - 9.3e-64 215.6 0.0 2.8e-63 214.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Mre11_DNA_bind PF04152.9 KNZ75398.1 - 1.6e-37 129.0 0.0 3.8e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KNZ75398.1 - 1.1e-26 93.5 0.8 1.5e-26 93.0 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KNZ75398.1 - 3.5e-07 30.1 0.0 2.6e-06 27.3 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribophorin_II PF05817.9 KNZ75398.1 - 0.011 14.0 0.0 0.017 13.3 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Drf_GBD PF06371.8 KNZ75398.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain ZZ PF00569.12 KNZ75399.1 - 0.00016 21.1 4.6 0.00026 20.4 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type ABC_tran PF00005.22 KNZ75400.1 - 3.5e-23 82.4 0.0 7e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KNZ75400.1 - 2.2e-09 37.7 0.0 2.4e-05 24.4 0.0 2.6 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 KNZ75400.1 - 2.9e-07 29.9 0.5 0.01 15.1 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KNZ75400.1 - 4.7e-05 23.5 0.0 0.01 15.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KNZ75400.1 - 0.00028 20.9 0.0 0.00075 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.1 KNZ75400.1 - 0.00065 18.8 0.0 0.009 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 KNZ75400.1 - 0.0012 19.2 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KNZ75400.1 - 0.0033 16.4 0.0 0.006 15.6 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_29 PF13555.1 KNZ75400.1 - 0.0038 16.7 0.0 0.0089 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KNZ75400.1 - 0.0046 16.1 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KNZ75400.1 - 0.011 15.1 0.2 0.044 13.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 KNZ75400.1 - 0.013 16.0 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein DUF815 PF05673.8 KNZ75400.1 - 0.031 13.2 0.0 0.058 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 KNZ75400.1 - 0.031 15.1 0.0 0.087 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KNZ75400.1 - 0.054 13.4 0.3 0.17 11.8 0.2 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 KNZ75400.1 - 0.059 13.3 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KNZ75400.1 - 0.065 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 KNZ75400.1 - 0.081 12.6 0.0 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 KNZ75400.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain RVT_3 PF13456.1 KNZ75401.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Asp_protease_2 PF13650.1 KNZ75403.1 - 0.00016 22.0 0.0 0.00032 21.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Aminotran_3 PF00202.16 KNZ75404.1 - 1.9e-38 132.1 0.0 1.7e-21 76.4 0.0 2.9 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 KNZ75404.1 - 1.2e-26 93.6 0.0 2e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain WD40 PF00400.27 KNZ75405.1 - 1.8e-22 78.3 4.5 8.1e-09 35.0 0.0 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 KNZ75405.1 - 0.0047 16.6 0.0 0.61 9.7 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A adh_short_C2 PF13561.1 KNZ75406.1 - 2.2e-21 76.7 0.0 2.5e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KNZ75406.1 - 6.3e-17 61.9 0.4 8.1e-17 61.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ75406.1 - 2.9e-06 27.0 0.1 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KNZ75407.1 - 2.1e-27 96.4 0.0 2.6e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KNZ75407.1 - 1.5e-19 70.5 0.0 1.9e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ75407.1 - 3.6e-10 39.7 0.0 5.1e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 KR domain WD40 PF00400.27 KNZ75408.1 - 4.8e-22 76.9 13.4 2.5e-06 27.1 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat SnoaL_2 PF12680.2 KNZ75408.1 - 0.011 16.0 0.0 0.055 13.8 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain DUF2358 PF10184.4 KNZ75408.1 - 0.015 15.2 0.1 0.026 14.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) Sulfate_transp PF00916.15 KNZ75409.1 - 3e-80 269.2 6.0 7.8e-80 267.8 4.2 1.7 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KNZ75409.1 - 2.1e-32 110.6 4.1 2.1e-32 110.6 2.8 3.1 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KNZ75409.1 - 8.8e-08 31.5 0.0 1.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KNZ75409.1 - 0.0066 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 STAS domain Transcrip_reg PF01709.15 KNZ75410.1 - 2.7e-49 167.4 5.4 6.1e-45 153.1 0.1 2.0 2 0 0 2 2 2 2 Transcriptional regulator NYN PF01936.13 KNZ75411.1 - 5.1e-13 49.5 0.0 9.5e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 NYN domain Peptidase_C14 PF00656.17 KNZ75412.1 - 3.7e-06 26.8 0.0 6.1e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 KNZ75413.1 - 4.1e-18 65.9 0.0 8.8e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Caspase domain AAA_16 PF13191.1 KNZ75413.1 - 0.068 13.1 0.7 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain NYN PF01936.13 KNZ75414.1 - 2.1e-43 148.1 0.2 2.8e-23 82.8 0.0 2.4 2 0 0 2 2 2 2 NYN domain CHCH PF06747.8 KNZ75415.1 - 0.00022 21.0 0.7 0.00028 20.7 0.5 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 KNZ75415.1 - 0.025 14.3 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Tweety PF04906.8 KNZ75415.1 - 0.029 12.7 0.1 0.034 12.5 0.1 1.0 1 0 0 1 1 1 0 Tweety UQ_con PF00179.21 KNZ75416.1 - 8.5e-22 77.1 0.0 1.9e-21 75.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme zf-RanBP PF00641.13 KNZ75416.1 - 0.29 10.2 0.1 0.29 10.2 0.1 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others L31 PF09784.4 KNZ75417.1 - 4.3e-34 116.6 2.3 1.2e-31 108.8 0.3 2.5 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L31 CMS1 PF14617.1 KNZ75418.1 - 1.6e-81 273.1 2.9 1.9e-81 272.8 2.0 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DUF1675 PF07897.6 KNZ75418.1 - 0.0008 19.3 0.7 0.0011 18.8 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1675) DUF2026 PF09641.5 KNZ75418.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2026) YL1 PF05764.8 KNZ75418.1 - 0.18 11.3 9.6 0.26 10.8 6.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein RNase_T PF00929.19 KNZ75419.1 - 1.4e-12 48.1 0.0 1.4e-11 44.9 0.0 2.0 1 1 0 1 1 1 1 Exonuclease Ndc80_HEC PF03801.8 KNZ75420.1 - 2.5e-36 124.5 0.0 5.5e-36 123.4 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family Fib_alpha PF08702.5 KNZ75420.1 - 0.001 19.2 1.3 0.001 19.2 0.9 3.4 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family Myosin_tail_1 PF01576.14 KNZ75420.1 - 0.043 11.5 35.9 0.064 10.9 7.8 2.4 2 0 0 2 2 2 0 Myosin tail EzrA PF06160.7 KNZ75420.1 - 0.21 9.7 25.6 0.095 10.8 0.3 2.5 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA ATG16 PF08614.6 KNZ75420.1 - 0.91 9.3 32.3 0.2 11.4 2.1 4.0 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.7 KNZ75420.1 - 1.3 9.3 9.9 2 8.7 0.1 4.0 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4463 PF14703.1 KNZ75420.1 - 6 7.4 12.7 0.24 11.9 1.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) Flagellin_N PF00669.15 KNZ75420.1 - 7.6 6.3 9.5 2.2 8.0 0.1 4.0 2 1 2 4 4 4 0 Bacterial flagellin N-terminal helical region DUF342 PF03961.8 KNZ75420.1 - 7.6 4.8 21.3 0.85 7.9 5.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF342) Mog1 PF04603.7 KNZ75421.1 - 1.5e-30 105.9 0.1 1.9e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein DUF2383 PF09537.5 KNZ75422.1 - 1.2e-05 25.4 4.6 0.044 14.0 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF2383) bZIP_1 PF00170.16 KNZ75422.1 - 0.015 15.2 15.5 0.07 13.0 0.7 3.6 3 0 0 3 3 3 0 bZIP transcription factor PaREP1 PF05942.6 KNZ75422.1 - 0.024 14.4 2.0 0.024 14.4 1.4 2.5 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family WD40_alt PF14077.1 KNZ75422.1 - 0.1 12.2 0.1 0.33 10.6 0.1 1.8 1 0 0 1 1 1 0 Alternative WD40 repeat motif COQ7 PF03232.8 KNZ75422.1 - 0.2 11.1 5.6 0.85 9.0 0.3 2.5 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 DUF972 PF06156.8 KNZ75422.1 - 0.5 10.7 13.0 1.1 9.6 1.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) AAA_23 PF13476.1 KNZ75422.1 - 0.79 10.0 6.6 0.77 10.0 0.7 2.6 2 1 0 2 2 2 0 AAA domain CCDC92 PF14916.1 KNZ75422.1 - 0.85 9.2 7.5 2.7 7.6 0.1 2.9 3 0 0 3 3 3 0 Coiled-coil domain of unknown function DUF904 PF06005.7 KNZ75422.1 - 1.9 8.8 16.1 5.8 7.2 0.7 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF3829 PF12889.2 KNZ75422.1 - 2.4 7.2 12.9 1.7 7.7 2.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3829) DivIVA PF05103.8 KNZ75422.1 - 3.6 7.6 23.7 0.53 10.3 1.6 3.2 3 0 0 3 3 3 0 DivIVA protein TBPIP PF07106.8 KNZ75422.1 - 8.3 5.9 17.8 2.2 7.8 3.1 3.1 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CorA PF01544.13 KNZ75422.1 - 9.4 5.1 9.4 13 4.7 0.3 2.9 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein ATG16 PF08614.6 KNZ75422.1 - 9.6 5.9 18.4 0.4 10.4 1.2 3.1 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) HECT PF00632.20 KNZ75423.1 - 4.5e-89 298.7 0.0 6.1e-89 298.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KNZ75423.1 - 2.1e-34 116.9 22.7 2.8e-11 43.0 4.9 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KNZ75423.1 - 3.1e-16 58.9 0.2 8.2e-16 57.6 0.1 1.8 1 0 0 1 1 1 1 C2 domain Pox_MCEL PF03291.11 KNZ75424.1 - 1.3e-78 264.2 0.0 1.9e-78 263.6 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 KNZ75424.1 - 5.1e-08 32.7 0.0 9.5e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ75424.1 - 6.3e-08 33.0 0.1 1.3e-06 28.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ75424.1 - 1.3e-07 31.9 0.0 3.4e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ75424.1 - 5.4e-07 29.3 0.0 3.6e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ75424.1 - 7e-07 29.8 0.0 1.5e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ75424.1 - 7.3e-06 26.2 0.1 2.1e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ75424.1 - 7.6e-05 22.7 0.0 0.00021 21.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KNZ75424.1 - 0.0062 15.9 0.0 0.015 14.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.6 KNZ75424.1 - 0.044 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) NNMT_PNMT_TEMT PF01234.12 KNZ75424.1 - 0.065 12.2 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 KNZ75424.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Peptidase_M1 PF01433.15 KNZ75425.1 - 7.4e-112 374.2 0.3 5.9e-110 368.0 0.2 2.2 1 1 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KNZ75425.1 - 2e-63 214.5 0.1 3.1e-63 213.9 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KNZ75425.1 - 7.3e-16 58.3 0.0 1.5e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Bestrophin PF01062.16 KNZ75427.1 - 1.2e-45 155.7 0.0 2.9e-27 95.3 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel 2Fe-2S_thioredx PF01257.14 KNZ75428.1 - 1.4e-56 190.1 0.0 1.7e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Telomere_reg-2 PF10193.4 KNZ75429.1 - 6.1e-27 94.1 0.0 1.4e-26 93.0 0.0 1.6 1 0 0 1 1 1 1 Telomere length regulation protein Peptidase_S41 PF03572.13 KNZ75430.1 - 1.4e-05 24.5 0.0 3.7e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Linker_histone PF00538.14 KNZ75431.1 - 1.2e-12 47.7 1.8 5.3e-12 45.6 0.0 2.3 2 1 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.6 KNZ75431.1 - 7.2 6.4 71.5 4.8 6.9 48.1 1.7 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 Linker_histone PF00538.14 KNZ75433.1 - 1.4e-12 47.5 1.3 1.5e-12 47.3 0.0 1.8 2 0 0 2 2 2 1 linker histone H1 and H5 family RRM_1 PF00076.17 KNZ75435.1 - 7.3e-26 89.6 0.0 2.5e-12 46.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 KNZ75435.1 - 1.2e-19 68.6 0.0 8.5e-05 21.8 0.0 5.8 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_6 PF14259.1 KNZ75435.1 - 3.6e-17 62.0 0.0 1.9e-07 30.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ75435.1 - 2.7e-14 52.7 0.0 9.9e-07 28.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3517 PF12030.3 KNZ75435.1 - 0.25 9.8 0.0 0.39 9.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) Nab6_mRNP_bdg PF10567.4 KNZ75435.1 - 0.35 9.7 0.0 0.6 9.0 0.0 1.3 1 0 0 1 1 1 0 RNA-recognition motif NTP_transf_5 PF14907.1 KNZ75436.1 - 0.042 13.1 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase RCC1 PF00415.13 KNZ75437.1 - 4e-18 65.3 7.5 0.00018 21.6 0.0 8.1 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KNZ75437.1 - 2e-07 30.4 0.3 6.1e-06 25.6 0.0 6.3 7 0 0 7 7 7 2 Regulator of chromosome condensation (RCC1) repeat DUF4394 PF14339.1 KNZ75437.1 - 0.08 12.2 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) YL1 PF05764.8 KNZ75438.1 - 0.26 10.8 8.0 0.51 9.9 5.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein MCPVI PF02993.9 KNZ75438.1 - 0.31 11.1 5.9 0.62 10.1 4.1 1.4 1 0 0 1 1 1 0 Minor capsid protein VI DPBB_1 PF03330.13 KNZ75439.1 - 0.0025 17.7 0.0 0.0071 16.3 0.0 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF2217 PF10265.4 KNZ75439.1 - 2.2 6.9 9.2 2.7 6.6 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Trypan_PARP PF05887.6 KNZ75439.1 - 4.8 7.0 13.0 8.6 6.1 9.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF822 PF05687.8 KNZ75439.1 - 8 6.8 8.9 13 6.1 6.1 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) DPBB_1 PF03330.13 KNZ75440.1 - 0.0017 18.3 0.0 0.0038 17.2 0.0 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF822 PF05687.8 KNZ75440.1 - 3.7 7.8 8.9 6.4 7.1 6.2 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) DPBB_1 PF03330.13 KNZ75441.1 - 0.035 14.0 0.0 0.12 12.4 0.0 2.0 1 1 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel E1-E2_ATPase PF00122.15 KNZ75442.1 - 1.7e-66 223.5 7.0 4.4e-65 218.9 4.5 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KNZ75442.1 - 4.4e-44 150.1 9.7 5.7e-44 149.8 5.9 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KNZ75442.1 - 5.1e-29 102.2 0.0 6.2e-28 98.6 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KNZ75442.1 - 2.8e-22 77.9 0.0 4.9e-20 70.7 0.0 3.0 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KNZ75442.1 - 4e-22 77.9 0.1 8.2e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KNZ75442.1 - 1.6e-13 51.2 0.0 7.2e-13 49.1 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KNZ75442.1 - 1.5e-06 27.9 2.2 1.4e-05 24.8 1.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KNZ75442.1 - 0.0022 18.2 0.0 0.005 17.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.1 KNZ75443.1 - 0.98 9.1 9.2 2 8.1 6.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ75443.1 - 7 6.7 12.5 13 5.9 8.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nuc_sug_transp PF04142.10 KNZ75445.1 - 2e-08 33.6 1.0 2.6e-08 33.2 0.7 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 KNZ75445.1 - 2.9e-05 24.2 5.8 2.9e-05 24.2 4.0 2.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KNZ75445.1 - 0.00086 19.3 7.3 0.00086 19.3 5.1 3.2 2 1 0 2 2 2 1 EamA-like transporter family UAA PF08449.6 KNZ75445.1 - 0.13 11.1 9.9 0.21 10.4 6.9 1.2 1 0 0 1 1 1 0 UAA transporter family TPT PF03151.11 KNZ75445.1 - 6.6 6.3 18.6 0.98 9.0 2.5 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family SHQ1 PF04925.10 KNZ75446.1 - 1.7e-51 174.4 0.1 3e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 SHQ1 protein PIH1 PF08190.7 KNZ75446.1 - 4.3e-05 23.1 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 CS PF04969.11 KNZ75446.1 - 0.025 15.0 0.0 0.069 13.7 0.0 1.8 2 0 0 2 2 2 0 CS domain DUF1762 PF08574.5 KNZ75446.1 - 0.05 14.0 6.0 0.71 10.3 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1762) Chorismate_bind PF00425.13 KNZ75447.1 - 2.5e-89 299.0 0.0 4.1e-89 298.3 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 KNZ75447.1 - 7.4e-33 113.5 0.0 3.2e-31 108.2 0.0 2.6 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Ribosomal_S2 PF00318.15 KNZ75448.1 - 8.5e-43 146.0 0.0 7.8e-21 74.2 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 HSP70 PF00012.15 KNZ75449.1 - 6.7e-244 810.3 6.6 8.3e-244 810.0 4.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KNZ75449.1 - 4.5e-17 61.6 0.7 4.5e-16 58.3 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 KNZ75449.1 - 0.003 16.4 0.5 0.021 13.6 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 KNZ75449.1 - 0.0094 15.5 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 KNZ75449.1 - 0.014 14.7 0.3 1.6 7.9 0.1 2.6 2 1 1 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 KNZ75449.1 - 0.02 13.8 0.0 0.051 12.5 0.0 1.7 1 0 0 1 1 1 0 StbA protein Hydantoinase_A PF01968.13 KNZ75449.1 - 0.024 13.7 1.9 0.088 11.8 0.0 2.6 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase AAA PF00004.24 KNZ75450.1 - 5e-14 52.6 0.0 1.4e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KNZ75450.1 - 8.4e-13 48.2 0.0 6.1e-12 45.5 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KNZ75450.1 - 3.6e-12 45.7 0.0 1.5e-07 30.4 0.0 2.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 KNZ75450.1 - 3.9e-10 39.5 0.0 9.1e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 KNZ75450.1 - 2.9e-07 30.6 0.0 1.7e-06 28.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KNZ75450.1 - 3e-05 23.7 0.0 5.4e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ75450.1 - 4.6e-05 23.4 0.1 0.00041 20.3 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KNZ75450.1 - 8.3e-05 22.2 0.0 0.00022 20.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KNZ75450.1 - 9.8e-05 21.5 0.0 0.00022 20.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KNZ75450.1 - 0.0003 20.6 0.0 0.00056 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KNZ75450.1 - 0.00034 20.2 0.0 0.00098 18.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KNZ75450.1 - 0.00058 19.5 0.0 0.0019 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KNZ75450.1 - 0.0011 18.2 0.0 0.021 13.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KNZ75450.1 - 0.0032 17.0 0.0 0.0069 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KNZ75450.1 - 0.0045 16.0 0.0 0.0073 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 KNZ75450.1 - 0.016 14.6 0.1 0.46 9.8 0.0 2.4 2 1 0 3 3 3 0 AAA-like domain AAA_25 PF13481.1 KNZ75450.1 - 0.025 13.9 0.0 0.086 12.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KNZ75450.1 - 0.028 14.7 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KNZ75450.1 - 0.029 15.1 0.0 0.064 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 KNZ75450.1 - 0.03 13.8 0.1 0.44 10.0 0.0 2.5 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_28 PF13521.1 KNZ75450.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KNZ75450.1 - 0.088 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_2 PF07724.9 KNZ75450.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sec3_C_2 PF15278.1 KNZ75450.1 - 0.13 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Sec3 exocyst complex subunit ResIII PF04851.10 KNZ75450.1 - 0.14 11.9 0.0 0.37 10.6 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CAF1A PF12253.3 KNZ75451.1 - 1.8e-16 60.0 0.1 1.8e-16 60.0 0.1 2.0 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A WWE PF02825.15 KNZ75451.1 - 0.043 13.2 0.1 0.17 11.3 0.1 2.0 1 0 0 1 1 1 0 WWE domain GAGA_bind PF06217.7 KNZ75451.1 - 0.78 9.6 8.0 0.62 9.9 3.9 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family SRP-alpha_N PF04086.8 KNZ75451.1 - 0.9 8.8 13.3 8.2 5.7 7.0 2.6 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal RR_TM4-6 PF06459.7 KNZ75451.1 - 2.2 8.1 10.3 5.6 6.7 7.2 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spc24 PF08286.6 KNZ75452.1 - 6.7e-15 54.8 0.4 2.1e-14 53.2 0.0 1.8 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Med9 PF07544.8 KNZ75452.1 - 0.0026 17.4 4.5 0.05 13.3 0.2 2.3 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 PsiA PF06952.6 KNZ75452.1 - 0.029 13.4 0.2 0.04 12.9 0.2 1.2 1 0 0 1 1 1 0 PsiA protein V_ATPase_I PF01496.14 KNZ75452.1 - 0.085 10.7 2.4 0.095 10.5 1.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vps51 PF08700.6 KNZ75452.1 - 0.1 12.4 2.4 0.67 9.8 0.1 2.3 2 0 0 2 2 2 0 Vps51/Vps67 SlyX PF04102.7 KNZ75452.1 - 0.14 12.5 2.7 12 6.3 0.1 2.4 2 0 0 2 2 2 0 SlyX Reo_sigmaC PF04582.7 KNZ75452.1 - 0.15 11.1 0.9 0.19 10.8 0.6 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 KNZ75452.1 - 0.17 11.8 2.0 3.1 7.7 0.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 KNZ75452.1 - 0.19 10.7 8.1 0.24 10.3 5.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KNZ75452.1 - 0.28 10.7 6.2 0.61 9.6 4.0 1.7 1 1 0 1 1 1 0 IncA protein DivIC PF04977.10 KNZ75452.1 - 0.43 10.0 5.4 0.8 9.2 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 KNZ75452.1 - 0.73 10.2 3.8 0.47 10.8 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Caudo_TAP PF02413.12 KNZ75452.1 - 1.9 8.6 5.7 1.1 9.4 2.5 1.6 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein TMF_DNA_bd PF12329.3 KNZ75452.1 - 2.1 8.2 12.0 0.16 11.7 1.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding T2SM PF04612.7 KNZ75452.1 - 2.1 8.1 6.9 10 5.8 1.4 2.2 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M Prefoldin_2 PF01920.15 KNZ75452.1 - 8 6.2 8.8 44 3.8 6.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit ADH_zinc_N_2 PF13602.1 KNZ75453.1 - 3.1e-17 63.6 0.0 9.6e-17 62.0 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KNZ75453.1 - 1.1e-12 47.6 0.0 5.1e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ75453.1 - 0.016 14.9 0.0 0.092 12.5 0.0 2.1 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain Peptidase_A21 PF03566.8 KNZ75453.1 - 0.082 10.9 0.1 0.11 10.5 0.1 1.1 1 0 0 1 1 1 0 Peptidase family A21 CRM1_C PF08767.6 KNZ75454.1 - 1.8e-132 441.0 1.6 1.8e-132 441.0 1.1 3.4 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 KNZ75454.1 - 9.4e-33 113.2 5.1 9.4e-33 113.2 3.5 3.6 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 KNZ75454.1 - 2.6e-11 43.2 0.0 7.5e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain PUA PF01472.15 KNZ75455.1 - 2.2e-12 46.5 0.1 3.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 PUA domain SRR1 PF07985.7 KNZ75456.1 - 7e-09 35.4 0.2 1.1e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 SRR1 TPR_11 PF13414.1 KNZ75458.1 - 1.4e-27 95.1 19.0 2.8e-08 33.2 0.3 7.7 7 1 1 8 8 8 4 TPR repeat TPR_1 PF00515.23 KNZ75458.1 - 1.1e-25 88.1 3.8 1.2e-07 31.0 0.1 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ75458.1 - 1.1e-23 83.3 15.3 2.1e-06 28.2 0.1 8.6 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ75458.1 - 4.3e-23 79.3 13.5 0.00023 20.8 0.1 9.8 10 0 0 10 10 9 5 Tetratricopeptide repeat Apc3 PF12895.2 KNZ75458.1 - 2e-17 63.0 16.4 2.7e-13 49.8 1.2 5.3 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KNZ75458.1 - 3.1e-16 59.0 14.2 3.7e-06 26.7 0.0 7.9 5 1 4 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ75458.1 - 1.6e-14 52.5 0.0 0.0064 16.1 0.0 8.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ75458.1 - 3.6e-14 51.9 15.7 0.027 15.0 0.2 8.8 5 2 3 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ75458.1 - 4.8e-14 51.2 4.4 0.077 13.2 0.0 8.6 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ75458.1 - 4.8e-14 52.4 14.1 0.0044 17.3 0.0 8.2 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ75458.1 - 2.7e-09 36.8 5.7 0.72 10.4 0.0 8.4 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ75458.1 - 6.9e-06 25.4 5.5 1.2 9.1 0.0 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ75458.1 - 4.4e-05 23.2 10.3 0.034 13.9 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 KNZ75458.1 - 0.00038 19.6 11.1 0.041 12.9 1.4 3.5 3 1 2 5 5 5 3 Tetratricopeptide repeat NARP1 PF12569.3 KNZ75458.1 - 0.025 13.3 0.2 3.6 6.2 0.0 3.0 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.1 KNZ75458.1 - 0.13 12.1 8.9 42 4.2 0.1 6.2 5 1 1 6 6 6 0 Tetratricopeptide repeat ICL PF00463.16 KNZ75458.1 - 0.15 10.2 0.1 0.9 7.6 0.0 1.9 2 0 0 2 2 2 0 Isocitrate lyase family TPR_4 PF07721.9 KNZ75458.1 - 0.97 10.0 6.2 10 6.9 0.3 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.19 KNZ75459.1 - 8.4e-141 469.9 11.2 9.5e-141 469.7 7.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 KNZ75459.1 - 0.00064 19.0 0.4 0.0015 17.7 0.1 1.8 2 1 0 2 2 2 1 Telomere recombination Rhodanese PF00581.15 KNZ75460.1 - 2.2e-13 50.5 0.0 4.3e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Lipase_GDSL_2 PF13472.1 KNZ75461.1 - 1.9e-26 93.3 0.0 2.5e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KNZ75461.1 - 3.7e-25 89.1 0.0 4.7e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KNZ75461.1 - 0.037 13.7 0.1 0.68 9.6 0.0 2.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family tRNA_int_endo PF01974.12 KNZ75462.1 - 8e-14 51.2 0.0 2.2e-13 49.8 0.0 1.6 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain DUF4355 PF14265.1 KNZ75462.1 - 0.075 12.9 7.5 0.1 12.5 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Remorin_C PF03763.8 KNZ75462.1 - 0.32 10.5 12.5 0.038 13.5 5.8 1.6 2 0 0 2 2 2 0 Remorin, C-terminal region EI24 PF07264.6 KNZ75463.1 - 1.3e-29 103.2 8.8 1.5e-29 102.9 6.1 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) RNA_pol_Rpb6 PF01192.17 KNZ75463.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb6 Linker_histone PF00538.14 KNZ75464.1 - 2.1e-14 53.3 0.0 5.6e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 linker histone H1 and H5 family RF-1 PF00472.15 KNZ75465.1 - 8.9e-26 89.9 3.3 2.4e-25 88.5 2.3 1.7 1 0 0 1 1 1 1 RF-1 domain EphA2_TM PF14575.1 KNZ75465.1 - 0.23 11.8 1.2 0.61 10.5 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4415 PF14384.1 KNZ75465.1 - 0.25 11.5 2.4 5.6 7.1 0.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4415) CAP_N PF01213.14 KNZ75466.1 - 4e-70 236.5 2.6 4e-70 236.5 1.8 3.1 1 1 2 3 3 3 2 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KNZ75466.1 - 5e-59 198.1 3.3 6.7e-59 197.7 2.3 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KNZ75466.1 - 0.0012 18.2 2.4 0.0021 17.4 1.3 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C SPRY PF00622.23 KNZ75468.1 - 6.5e-09 35.9 0.0 3.5e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 SPRY domain UQ_con PF00179.21 KNZ75469.1 - 2.4e-28 98.3 0.0 2.8e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Nt_Gln_amidase PF09764.4 KNZ75473.1 - 1.3e-24 86.4 0.1 1.5e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase ATP12 PF07542.6 KNZ75475.1 - 3.6e-24 85.0 0.9 6.6e-24 84.2 0.6 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein MutS_V PF00488.16 KNZ75476.1 - 1.6e-82 276.4 0.0 4.7e-82 274.9 0.0 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 KNZ75476.1 - 6.8e-39 133.7 1.4 1.5e-38 132.6 1.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KNZ75476.1 - 1.2e-22 80.1 0.0 2.4e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KNZ75476.1 - 1.9e-11 44.1 0.1 2.4e-10 40.5 0.0 2.7 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 KNZ75476.1 - 0.053 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 MutS family domain IV DNA_pol_phi PF04931.8 KNZ75477.1 - 3.9e-59 200.2 13.2 1.4e-48 165.2 7.0 3.4 4 1 0 4 4 4 2 DNA polymerase phi Glycos_transf_1 PF00534.15 KNZ75478.1 - 1.2e-20 73.6 0.0 2.6e-20 72.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KNZ75478.1 - 1e-10 41.8 0.0 2.5e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KNZ75478.1 - 7.2e-06 26.1 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 TF_Zn_Ribbon PF08271.7 KNZ75479.1 - 0.00052 19.2 0.4 0.001 18.3 0.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding RRN7 PF11781.3 KNZ75479.1 - 0.0026 17.2 1.0 0.0046 16.4 0.7 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 TFIIB PF00382.14 KNZ75479.1 - 0.039 13.7 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DZR PF12773.2 KNZ75479.1 - 0.067 13.0 0.8 0.13 12.0 0.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 KNZ75479.1 - 0.16 11.2 0.7 0.32 10.2 0.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Abhydrolase_6 PF12697.2 KNZ75480.1 - 2.6e-24 86.3 0.0 3e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ75480.1 - 9.9e-19 67.7 0.0 1.3e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ75480.1 - 9.9e-08 31.8 0.0 1.5e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KNZ75480.1 - 7.2e-06 26.3 0.0 9.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 KNZ75480.1 - 0.0053 16.3 0.0 0.0074 15.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 KNZ75480.1 - 0.074 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Lipase_3 PF01764.20 KNZ75480.1 - 0.097 12.2 0.0 0.56 9.8 0.0 2.0 1 1 1 2 2 2 0 Lipase (class 3) NUDE_C PF04880.8 KNZ75481.1 - 0.034 14.5 1.1 0.034 14.5 0.8 2.8 2 1 1 3 3 3 0 NUDE protein, C-terminal conserved region NAC PF01849.13 KNZ75482.1 - 5.2e-21 73.9 0.0 9.7e-21 73.0 0.0 1.5 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 KNZ75482.1 - 0.0041 16.9 0.5 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 KNZ75482.1 - 0.057 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain Methyltransf_11 PF08241.7 KNZ75483.1 - 1.2e-08 35.2 0.0 2.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ75483.1 - 3.2e-05 23.5 0.0 5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ75483.1 - 0.00092 19.7 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ75483.1 - 0.0021 17.7 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ75483.1 - 0.0032 17.9 0.0 0.006 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Glyco_tran_28_C PF04101.11 KNZ75484.1 - 5.2e-29 101.0 0.0 5.9e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KNZ75484.1 - 2.5e-07 30.1 0.0 3.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 P5CR_dimer PF14748.1 KNZ75485.1 - 7.5e-40 135.2 3.1 8.2e-40 135.1 1.5 1.5 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KNZ75485.1 - 4.8e-09 36.5 0.0 1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.24 KNZ75486.1 - 2.5e-44 150.6 0.0 5e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KNZ75486.1 - 1.1e-08 34.8 0.1 3.8e-08 33.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KNZ75486.1 - 1.7e-07 31.3 0.0 3.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KNZ75486.1 - 3.2e-07 30.5 0.0 1e-06 28.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KNZ75486.1 - 2e-06 27.9 0.6 0.00032 20.8 0.4 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KNZ75486.1 - 3e-06 26.3 0.0 5e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KNZ75486.1 - 0.00017 21.4 0.0 0.00053 19.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KNZ75486.1 - 0.00021 20.9 0.1 0.00052 19.7 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KNZ75486.1 - 0.00027 20.9 0.0 0.00057 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KNZ75486.1 - 0.0008 18.5 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KNZ75486.1 - 0.0016 17.8 0.9 0.016 14.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.10 KNZ75486.1 - 0.0018 18.0 0.0 0.0068 16.1 0.0 1.9 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.17 KNZ75486.1 - 0.002 18.2 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 KNZ75486.1 - 0.0023 17.6 0.1 0.064 12.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 KNZ75486.1 - 0.0025 18.6 0.0 0.0059 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KNZ75486.1 - 0.0039 16.6 0.0 0.012 15.0 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein UPF0079 PF02367.12 KNZ75486.1 - 0.0066 16.0 0.1 0.041 13.5 0.0 2.0 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KNZ75486.1 - 0.0081 16.4 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KNZ75486.1 - 0.0084 15.7 0.0 0.018 14.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KNZ75486.1 - 0.0091 15.1 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KNZ75486.1 - 0.0095 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KNZ75486.1 - 0.011 14.5 0.0 0.018 13.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_33 PF13671.1 KNZ75486.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KNZ75486.1 - 0.015 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KNZ75486.1 - 0.019 14.5 0.1 0.039 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KNZ75486.1 - 0.027 14.1 0.0 0.2 11.3 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 KNZ75486.1 - 0.03 13.4 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AFG1_ATPase PF03969.11 KNZ75486.1 - 0.032 13.0 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Bac_DnaA PF00308.13 KNZ75486.1 - 0.069 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 KNZ75486.1 - 0.096 11.7 0.1 0.48 9.5 0.0 2.0 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.21 KNZ75486.1 - 0.1 12.0 0.3 1.4 8.3 0.0 2.5 3 1 0 3 3 3 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KNZ75486.1 - 0.15 10.8 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RRM_1 PF00076.17 KNZ75487.1 - 4.2e-12 45.5 0.0 1.2e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ75487.1 - 2.2e-09 37.1 0.0 3.2e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ75487.1 - 1.6e-05 24.6 0.0 5.4e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ75488.1 - 0.0018 18.2 0.0 0.043 13.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 KNZ75489.1 - 3.5e-29 101.8 26.3 5.4e-29 101.2 18.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) CDC45 PF02724.9 KNZ75489.1 - 4.5 5.1 9.7 4.5 5.1 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein SUI1 PF01253.17 KNZ75490.1 - 6.5e-30 102.7 1.4 7.9e-30 102.5 1.0 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF608 PF04685.8 KNZ75490.1 - 0.018 13.7 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF608 rRNA_processing PF08524.6 KNZ75491.1 - 0.037 13.8 12.1 1.3e+02 2.2 8.4 2.6 1 1 0 1 1 1 0 rRNA processing PPP4R2 PF09184.6 KNZ75492.1 - 3e-24 86.0 0.1 3.6e-24 85.8 0.0 1.4 1 1 0 1 1 1 1 PPP4R2 PAP2 PF01569.16 KNZ75493.1 - 1.2e-28 99.3 1.1 2.1e-28 98.5 0.8 1.4 1 0 0 1 1 1 1 PAP2 superfamily Cullin_binding PF03556.10 KNZ75494.1 - 2.5e-25 88.8 2.2 3.6e-25 88.3 1.6 1.3 1 0 0 1 1 1 1 Cullin binding DUF59 PF01883.14 KNZ75495.1 - 1.1e-13 50.8 0.1 2.4e-13 49.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF59 MRG PF05712.8 KNZ75497.1 - 3.4e-45 153.3 0.0 5.3e-45 152.7 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KNZ75497.1 - 6.6e-07 28.9 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Pkinase PF00069.20 KNZ75498.1 - 1.5e-28 99.6 0.0 1.9e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ75498.1 - 2.5e-09 36.6 0.0 3.3e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ75498.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pyr_redox_3 PF13738.1 KNZ75499.1 - 9.6e-21 74.7 0.0 5.2e-19 69.1 0.0 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KNZ75499.1 - 3.1e-11 42.7 0.3 9.9e-10 37.8 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KNZ75499.1 - 2.8e-09 37.1 0.1 0.0074 16.1 0.0 3.5 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ75499.1 - 3.7e-09 36.4 0.1 1.4e-06 28.2 0.0 3.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KNZ75499.1 - 3.8e-09 35.2 0.0 1.7e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.19 KNZ75499.1 - 7.2e-08 31.7 1.3 0.0084 15.0 0.1 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KNZ75499.1 - 4.5e-07 30.1 0.5 0.0005 20.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KNZ75499.1 - 1.4e-05 24.3 0.0 0.07 12.1 0.0 3.2 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 KNZ75499.1 - 2.2e-05 23.6 1.1 0.0013 17.8 0.0 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 KNZ75499.1 - 3.8e-05 23.4 2.5 0.055 13.2 0.0 3.6 3 1 0 3 3 2 2 FAD-NAD(P)-binding GIDA PF01134.17 KNZ75499.1 - 0.00026 20.0 1.9 2 7.1 0.2 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 KNZ75499.1 - 0.00026 21.2 0.0 0.066 13.4 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding ApbA PF02558.11 KNZ75499.1 - 0.00037 19.9 1.7 0.02 14.3 0.2 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KNZ75499.1 - 0.0011 18.6 0.9 0.28 10.8 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KNZ75499.1 - 0.0015 17.6 1.2 0.0022 17.1 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_10 PF13460.1 KNZ75499.1 - 0.0053 16.7 1.5 1.1 9.2 0.2 2.6 3 0 0 3 3 2 1 NADH(P)-binding Shikimate_DH PF01488.15 KNZ75499.1 - 0.0054 16.8 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KNZ75499.1 - 0.0055 15.2 6.0 0.023 13.1 0.2 3.5 4 0 0 4 4 4 1 HI0933-like protein Lycopene_cycl PF05834.7 KNZ75499.1 - 0.0064 15.4 0.1 4.6 6.0 0.1 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 KNZ75499.1 - 0.021 14.5 1.2 0.49 10.1 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 KNZ75499.1 - 0.047 12.8 0.0 9.2 5.3 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KNZ75499.1 - 0.11 12.9 0.6 23 5.4 0.1 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.19 KNZ75499.1 - 0.14 11.0 3.2 0.37 9.5 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 KNZ75499.1 - 0.3 9.6 2.5 21 3.5 0.1 3.0 3 0 0 3 3 3 0 Tryptophan halogenase Glyco_hydro_10 PF00331.15 KNZ75500.1 - 1.4e-97 326.5 0.3 2e-97 326.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 KNZ75500.1 - 3.3e-13 49.0 8.6 1.1e-12 47.3 6.0 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_10 PF00331.15 KNZ75501.1 - 2.4e-102 342.2 0.0 2.7e-102 342.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 PRELI PF04707.9 KNZ75501.1 - 0.041 13.4 0.0 0.14 11.6 0.0 1.8 1 1 1 2 2 2 0 PRELI-like family ALG3 PF05208.8 KNZ75502.1 - 7.5e-124 413.6 16.8 1e-123 413.2 11.7 1.1 1 0 0 1 1 1 1 ALG3 protein Cellulase PF00150.13 KNZ75502.1 - 5e-13 48.8 0.0 7.5e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TBP PF00352.16 KNZ75503.1 - 7.7e-63 207.8 0.1 7.7e-32 108.5 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KNZ75503.1 - 0.00056 19.9 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Dynamin_M PF01031.15 KNZ75504.1 - 2.4e-102 341.7 0.0 3.9e-102 341.0 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KNZ75504.1 - 6.4e-55 185.5 0.0 1.1e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KNZ75504.1 - 9e-25 86.3 2.0 2.9e-24 84.7 1.4 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KNZ75504.1 - 0.0016 18.3 0.1 0.024 14.5 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase BCS1_N PF08740.6 KNZ75505.1 - 2.3e-28 99.0 0.8 2.3e-28 99.0 0.6 2.5 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 KNZ75505.1 - 2.9e-16 59.8 0.0 9e-16 58.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNZ75505.1 - 4e-05 23.6 0.0 4e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KNZ75505.1 - 0.00019 20.9 0.2 0.013 14.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 KNZ75505.1 - 0.0031 17.0 0.9 0.0088 15.5 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 KNZ75505.1 - 0.022 14.6 0.0 0.022 14.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KNZ75505.1 - 0.027 15.2 0.0 0.027 15.2 0.0 2.8 2 1 0 2 2 1 0 AAA domain DUF4262 PF14081.1 KNZ75505.1 - 0.033 14.3 0.1 0.11 12.5 0.0 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4262) AAA_19 PF13245.1 KNZ75505.1 - 0.053 13.2 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 KNZ75505.1 - 0.088 12.9 0.1 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KNZ75505.1 - 0.25 11.6 0.0 0.25 11.6 0.0 2.6 2 1 0 2 2 1 0 ABC transporter AAA_11 PF13086.1 KNZ75505.1 - 1.9 7.9 0.0 1.9 7.9 0.0 3.2 2 1 0 2 2 1 0 AAA domain TFIIF_alpha PF05793.7 KNZ75505.1 - 4.8 5.4 45.7 8.1 4.6 31.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Glyco_hydro_88 PF07470.8 KNZ75506.1 - 2.4e-12 46.5 0.0 1.2e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Pkinase PF00069.20 KNZ75507.1 - 4.6e-48 163.6 0.0 6.6e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ75507.1 - 3.7e-17 62.2 0.0 2.6e-16 59.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ75507.1 - 2.6e-06 27.3 0.0 0.0026 17.5 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KNZ75507.1 - 2.7e-06 26.5 0.0 5.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SMI1_KNR4 PF09346.5 KNZ75508.1 - 4.4e-24 84.9 0.0 7.8e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) p450 PF00067.17 KNZ75509.1 - 8.9e-23 80.5 0.0 9.6e-23 80.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ferric_reduct PF01794.14 KNZ75510.1 - 4.5e-13 49.3 17.1 5.2e-13 49.1 9.5 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KNZ75510.1 - 1.2e-10 41.5 0.0 2.2e-08 34.1 0.0 2.8 2 1 1 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KNZ75510.1 - 1.5e-06 28.0 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Aldedh PF00171.17 KNZ75511.1 - 9.3e-126 419.8 0.0 1.2e-125 419.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HSP90 PF00183.13 KNZ75512.1 - 9.5e-256 849.3 29.6 1.1e-255 849.0 20.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 KNZ75512.1 - 2e-11 43.5 0.0 4.2e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KNZ75512.1 - 4.6e-10 39.2 0.2 4.6e-10 39.2 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Aminotran_5 PF00266.14 KNZ75513.1 - 4.1e-32 111.3 0.0 7.3e-32 110.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V NHase_beta PF02211.10 KNZ75513.1 - 0.027 14.1 0.2 0.73 9.4 0.0 2.1 2 0 0 2 2 2 0 Nitrile hydratase beta subunit TRAPPC10 PF12584.3 KNZ75514.1 - 5.4e-28 97.3 0.0 1.3e-27 96.1 0.0 1.7 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.2 KNZ75514.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking DEAD PF00270.24 KNZ75515.1 - 2.2e-46 157.4 0.0 4.2e-46 156.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ75515.1 - 1.6e-22 79.1 0.0 5.1e-22 77.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ75515.1 - 0.00076 19.3 0.0 0.0035 17.1 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KNZ75515.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain Linker_histone PF00538.14 KNZ75516.1 - 1e-05 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family 2OG-FeII_Oxy_3 PF13640.1 KNZ75516.1 - 4.7e-05 23.8 0.0 0.0001 22.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KNZ75516.1 - 0.017 14.7 0.0 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily NTF2 PF02136.15 KNZ75517.1 - 5.9e-16 58.9 0.0 8.3e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain U3_assoc_6 PF08640.6 KNZ75518.1 - 0.14 11.9 0.1 0.39 10.5 0.0 1.7 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Med3 PF11593.3 KNZ75518.1 - 0.3 10.2 8.8 0.78 8.9 6.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pol_alpha_B_N PF08418.5 KNZ75518.1 - 2.8 7.4 7.0 0.39 10.2 1.6 1.9 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Glyco_hydro_88 PF07470.8 KNZ75519.1 - 1.7e-18 66.8 0.0 2e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 KNZ75519.1 - 0.05 12.8 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Pkinase PF00069.20 KNZ75520.1 - 2.1e-43 148.3 0.0 2.7e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ75520.1 - 4.3e-13 48.9 0.0 1.7e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ75520.1 - 1.8e-05 24.5 0.0 3.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KNZ75520.1 - 0.0059 15.6 0.0 0.019 13.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KNZ75521.1 - 5.3e-06 25.7 0.3 9.3e-06 24.9 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KNZ75521.1 - 3.5e-05 23.6 0.3 0.049 13.3 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KNZ75521.1 - 0.08 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.12 KNZ75521.1 - 0.091 11.8 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase WEMBL PF05701.6 KNZ75523.1 - 0.021 13.2 1.7 0.03 12.8 1.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Zn_clus PF00172.13 KNZ75523.1 - 1.4 8.8 8.9 3.8 7.4 0.6 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 KNZ75524.1 - 3.3e-22 78.7 0.0 1e-15 57.6 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ75524.1 - 2.3e-11 43.3 0.0 5.9e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ75524.1 - 4e-05 23.5 0.0 0.00017 21.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DSPc PF00782.15 KNZ75525.1 - 1.6e-28 98.9 0.0 2.3e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KNZ75525.1 - 0.0074 15.6 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 KNZ75525.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KNZ75525.1 - 0.019 15.2 0.0 0.05 13.8 0.0 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KNZ75525.1 - 0.025 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Glyco_hydro_31 PF01055.21 KNZ75526.1 - 1.1e-118 396.9 0.4 1.4e-118 396.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KNZ75526.1 - 5.7e-19 67.7 0.4 3.6e-18 65.1 0.2 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like Amidohydro_3 PF07969.6 KNZ75527.1 - 5.9e-71 239.8 0.1 6.9e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 KNZ75527.1 - 6.3e-08 32.6 0.0 0.00022 20.9 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KNZ75527.1 - 0.00053 20.1 0.3 0.93 9.4 0.1 2.9 2 1 1 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 KNZ75527.1 - 0.018 14.8 0.0 0.085 12.6 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase CTP_transf_2 PF01467.21 KNZ75528.1 - 1.3e-16 61.0 0.1 2.3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase DUF2786 PF10979.3 KNZ75529.1 - 6.6e-08 32.1 0.8 6.6e-08 32.1 0.6 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) Abhydrolase_2 PF02230.11 KNZ75530.1 - 1.4e-09 37.7 0.0 5.4e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KNZ75530.1 - 0.00014 21.8 0.1 0.00021 21.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ75530.1 - 0.0085 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4502 PF14950.1 KNZ75531.1 - 0.056 12.6 0.2 0.1 11.7 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4502) TFIIE_beta PF02186.10 KNZ75532.1 - 0.00019 21.3 0.3 0.00048 20.0 0.2 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain Yae1_N PF09811.4 KNZ75533.1 - 2.4e-12 46.1 1.3 4.1e-11 42.2 0.6 2.4 2 0 0 2 2 2 1 Essential protein Yae1, N terminal TipAS PF07739.8 KNZ75533.1 - 0.93 9.8 4.2 1.2 9.4 0.6 2.4 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain Abhydrolase_6 PF12697.2 KNZ75534.1 - 2.5e-26 92.9 0.0 4.6e-26 92.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ75534.1 - 3e-10 40.0 0.0 4.2e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ75534.1 - 6.5e-09 35.6 0.7 5.2e-08 32.7 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KNZ75534.1 - 0.0086 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KNZ75534.1 - 0.017 13.5 0.0 0.029 12.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family Peptidase_S74 PF13884.1 KNZ75534.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Chaperone of endosialidase Abhydrolase_6 PF12697.2 KNZ75535.1 - 2.3e-25 89.8 0.0 3.4e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ75535.1 - 5.4e-10 39.2 0.3 1e-08 35.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ75535.1 - 7.5e-10 38.7 0.0 1.3e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KNZ75535.1 - 0.088 12.2 0.0 0.18 11.1 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.3 KNZ75535.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S74 PF13884.1 KNZ75535.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Chaperone of endosialidase Gp_dh_C PF02800.15 KNZ75536.1 - 6e-72 240.2 0.0 8.1e-72 239.7 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KNZ75536.1 - 2e-55 186.9 0.1 4.5e-55 185.7 0.0 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Reo_sigmaC PF04582.7 KNZ75537.1 - 0.29 10.2 13.5 0.65 9.1 0.9 3.7 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Herpes_LMP2 PF07415.6 KNZ75537.1 - 0.56 8.7 0.4 1.1 7.7 0.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein AA_permease_2 PF13520.1 KNZ75538.1 - 8.8e-54 182.6 40.3 1.2e-53 182.1 28.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KNZ75538.1 - 4.2e-14 51.7 33.4 4.9e-14 51.5 22.5 1.5 1 1 0 1 1 1 1 Amino acid permease HLH PF00010.21 KNZ75539.1 - 4.1e-13 48.8 0.1 8.9e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3138 PF11336.3 KNZ75539.1 - 0.12 10.4 0.0 0.12 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Ldh_1_N PF00056.18 KNZ75540.1 - 1e-45 155.0 0.1 1.5e-45 154.4 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KNZ75540.1 - 5e-35 120.7 0.0 6.7e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KNZ75540.1 - 8.3e-05 21.4 0.0 0.00016 20.4 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CN_hydrolase PF00795.17 KNZ75542.1 - 1e-28 99.9 0.0 1.4e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DIOX_N PF14226.1 KNZ75543.1 - 4.2e-12 46.6 0.0 7.3e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KNZ75543.1 - 2.1e-10 40.7 0.0 3.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 KNZ75544.1 - 2.9e-27 95.3 11.4 3.7e-27 94.9 7.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ75544.1 - 6.6e-06 24.9 1.9 8.1e-06 24.6 1.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Bap31 PF05529.7 KNZ75545.1 - 1.4e-53 181.2 5.3 1.6e-53 181.0 3.7 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like GNT-I PF03071.10 KNZ75545.1 - 0.057 11.9 0.8 0.076 11.5 0.6 1.1 1 0 0 1 1 1 0 GNT-I family DUF1869 PF08956.5 KNZ75545.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) Peptidase_M4_C PF02868.10 KNZ75545.1 - 0.34 10.6 3.2 2 8.1 0.1 2.1 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain Seryl_tRNA_N PF02403.17 KNZ75545.1 - 0.51 10.3 4.9 0.91 9.5 3.4 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.6 KNZ75545.1 - 0.54 9.6 8.6 0.74 9.2 5.9 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Membr_traf_MHD PF10540.4 KNZ75548.1 - 8.5e-19 67.7 0.0 5.4e-18 65.1 0.0 2.5 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KNZ75548.1 - 1.8e-09 37.2 0.0 5.2e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 C2 domain PMG PF05287.7 KNZ75549.1 - 0.14 11.9 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 PMG protein HSP70 PF00012.15 KNZ75551.1 - 4.2e-74 249.5 6.2 4.2e-74 249.5 4.3 2.5 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KNZ75551.1 - 0.0032 16.1 2.1 0.015 13.8 1.5 2.0 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.11 KNZ75551.1 - 0.025 14.1 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 KNZ75551.1 - 0.06 12.6 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family RVP_2 PF08284.6 KNZ75552.1 - 0.13 12.2 0.1 0.51 10.2 0.0 1.8 1 1 1 2 2 2 0 Retroviral aspartyl protease HEAT_EZ PF13513.1 KNZ75553.1 - 5.5e-20 71.2 8.7 3.4e-10 40.1 0.0 9.7 9 3 2 11 11 11 2 HEAT-like repeat HEAT PF02985.17 KNZ75553.1 - 2.2e-16 58.3 14.1 6.3e-05 22.7 0.0 10.3 12 0 0 12 12 12 5 HEAT repeat HEAT_2 PF13646.1 KNZ75553.1 - 9.1e-16 57.9 6.7 8.4e-06 25.9 0.0 7.7 2 1 6 8 8 8 5 HEAT repeats IBN_N PF03810.14 KNZ75553.1 - 3.5e-12 46.0 0.7 8.5e-11 41.6 0.0 3.7 5 0 0 5 5 5 1 Importin-beta N-terminal domain Arm PF00514.18 KNZ75553.1 - 1.3e-08 34.3 8.3 0.0011 18.6 0.0 6.4 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat DUF3385 PF11865.3 KNZ75553.1 - 0.0011 18.8 0.1 0.4 10.5 0.0 4.2 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) CLASP_N PF12348.3 KNZ75553.1 - 0.0011 18.3 0.1 15 4.8 0.0 4.5 2 2 3 5 5 5 1 CLASP N terminal LSM PF01423.17 KNZ75554.1 - 3.2e-17 61.8 0.0 4e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain PAP_assoc PF03828.14 KNZ75556.1 - 1.9e-16 59.7 0.1 4.5e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KNZ75556.1 - 4.2e-05 23.7 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pkinase PF00069.20 KNZ75557.1 - 7.6e-07 28.5 0.0 2.4e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ75557.1 - 0.0011 18.0 0.4 0.0019 17.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase adh_short_C2 PF13561.1 KNZ75558.1 - 6.6e-24 85.0 0.0 8.3e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KNZ75558.1 - 3.8e-20 72.4 0.6 4.9e-20 72.1 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ75558.1 - 6.3e-10 39.0 0.2 8.7e-10 38.5 0.1 1.2 1 0 0 1 1 1 1 KR domain SET PF00856.23 KNZ75559.1 - 2.4e-13 50.7 0.1 1.7e-09 38.2 0.0 2.3 2 1 0 2 2 2 2 SET domain HTH_21 PF13276.1 KNZ75559.1 - 0.021 14.8 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 HTH-like domain Melibiase PF02065.13 KNZ75559.1 - 0.031 12.9 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 Melibiase UCH PF00443.24 KNZ75560.1 - 8.2e-41 139.8 0.0 1e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNZ75560.1 - 2.5e-16 59.9 0.0 7.2e-16 58.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KNZ75560.1 - 0.0036 16.6 0.0 0.0099 15.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family TetR_C_3 PF08362.6 KNZ75562.1 - 0.003 17.2 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region Maf PF02545.9 KNZ75565.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Maf-like protein DUF680 PF05079.7 KNZ75568.1 - 0.09 13.2 0.7 0.21 12.0 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF680) RINGv PF12906.2 KNZ75569.1 - 5.3e-06 26.3 6.5 8.8e-06 25.6 4.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KNZ75569.1 - 0.00022 20.9 5.5 0.00035 20.3 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KNZ75569.1 - 0.03 14.4 4.6 0.057 13.5 3.2 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger FANCL_C PF11793.3 KNZ75569.1 - 0.12 12.3 3.8 0.2 11.6 2.6 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 KNZ75569.1 - 0.15 11.7 3.5 0.24 11.0 2.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ75569.1 - 0.18 11.8 4.1 0.58 10.2 2.8 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.1 KNZ75569.1 - 0.26 10.8 0.1 0.26 10.8 0.1 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Complex1_LYR PF05347.10 KNZ75571.1 - 3.6e-11 42.7 0.8 7.6e-11 41.6 0.6 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KNZ75571.1 - 9.5e-10 38.5 0.3 1.8e-09 37.6 0.2 1.5 1 0 0 1 1 1 1 Complex1_LYR-like PP28 PF10252.4 KNZ75572.1 - 2.9e-24 84.8 28.4 3.5e-24 84.6 10.3 2.3 2 0 0 2 2 2 2 Casein kinase substrate phosphoprotein PP28 Nop53 PF07767.6 KNZ75572.1 - 1.3 7.9 38.6 0.048 12.6 20.4 2.0 1 1 1 2 2 2 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.9 KNZ75572.1 - 2 6.3 19.4 2.5 6.0 13.5 1.3 1 0 0 1 1 1 0 CDC45-like protein PPR_2 PF13041.1 KNZ75573.1 - 9.2e-08 31.9 0.0 0.00018 21.4 0.0 4.2 5 1 0 5 5 5 1 PPR repeat family PPR_3 PF13812.1 KNZ75573.1 - 7.7e-05 22.6 2.1 0.12 12.7 0.0 5.2 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR PF01535.15 KNZ75573.1 - 0.018 14.9 0.1 1.4 9.0 0.0 2.9 2 0 0 2 2 2 0 PPR repeat PPR_1 PF12854.2 KNZ75573.1 - 0.11 11.9 0.0 1.6 8.2 0.0 2.7 2 0 0 2 2 2 0 PPR repeat RRM_1 PF00076.17 KNZ75574.1 - 3e-11 42.7 0.0 1.2e-09 37.6 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ75574.1 - 2.6e-08 33.7 0.0 4.7e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ75574.1 - 1.1e-06 28.3 0.0 3.5e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KNZ75574.1 - 0.0054 16.4 0.0 0.008 15.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF1777 PF08648.7 KNZ75574.1 - 1.5 8.5 48.6 2.5 7.7 33.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Extensin_2 PF04554.8 KNZ75574.1 - 4.8 7.1 13.1 0.58 10.0 1.9 3.1 3 0 0 3 3 3 0 Extensin-like region rve PF00665.21 KNZ75576.1 - 6.9e-06 26.1 0.0 7.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain GvpH PF05455.6 KNZ75577.1 - 0.044 13.4 0.3 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 GvpH DUF4218 PF13960.1 KNZ75580.1 - 0.11 11.9 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) F-box-like PF12937.2 KNZ75582.1 - 0.018 14.7 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 KNZ75582.1 - 0.022 14.4 0.0 0.084 12.5 0.0 2.0 1 0 0 1 1 1 0 F-box domain RasGEF PF00617.14 KNZ75583.1 - 1.8e-23 83.2 0.0 1.6e-22 80.1 0.0 2.4 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 KNZ75583.1 - 1.5e-10 41.1 1.4 1.5e-10 41.1 0.9 2.3 3 0 0 3 3 3 1 RasGEF N-terminal motif ASF1_hist_chap PF04729.8 KNZ75584.1 - 4e-57 192.1 0.1 4.7e-57 191.9 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone eIF2_C PF09173.6 KNZ75587.1 - 1e-35 121.5 0.5 2.3e-35 120.5 0.4 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.22 KNZ75587.1 - 1.3e-35 122.5 0.0 2.5e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 KNZ75587.1 - 4.8e-11 42.6 1.8 6.8e-11 42.1 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KNZ75587.1 - 0.033 14.1 0.0 0.088 12.7 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dak1_2 PF13684.1 KNZ75587.1 - 0.036 13.0 0.4 0.059 12.3 0.3 1.3 1 0 0 1 1 1 0 Dihydroxyacetone kinase family p450 PF00067.17 KNZ75588.1 - 1.3e-69 234.9 0.0 1.6e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SET PF00856.23 KNZ75589.1 - 1.2e-20 74.4 0.2 1.2e-20 74.4 0.1 3.1 2 2 0 2 2 2 1 SET domain SRI PF08236.6 KNZ75589.1 - 5.3e-16 58.3 12.6 5.3e-16 58.3 7.5 2.0 1 1 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain RNA_pol_I_A49 PF06870.7 KNZ75590.1 - 1.3e-77 260.9 0.1 1.6e-77 260.7 0.0 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Pkinase PF00069.20 KNZ75591.1 - 7.8e-29 100.6 0.0 5.9e-28 97.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ75591.1 - 6.6e-18 64.7 0.0 1e-17 64.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ75591.1 - 4.9e-05 22.4 0.0 9.9e-05 21.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ75591.1 - 0.027 14.2 1.3 0.045 13.4 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family BP28CT PF08146.7 KNZ75592.1 - 3.8e-23 81.8 1.1 6.6e-22 77.8 0.2 3.4 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KNZ75592.1 - 1.3e-13 50.9 0.1 1.3e-13 50.9 0.1 6.3 7 0 0 7 7 7 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 KNZ75592.1 - 0.0031 17.4 0.3 0.13 12.3 0.2 4.0 3 0 0 3 3 3 1 HEAT repeat NotI PF12183.3 KNZ75592.1 - 0.28 10.2 0.1 0.49 9.4 0.1 1.3 1 0 0 1 1 1 0 Restriction endonuclease NotI PIF1 PF05970.9 KNZ75593.1 - 3.9e-20 72.1 0.0 4.7e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_31 PF13614.1 KNZ75593.1 - 0.051 13.5 0.1 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KNZ75593.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KNZ75593.1 - 0.079 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KNZ75593.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KNZ75593.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Polyketide_cyc2 PF10604.4 KNZ75594.1 - 0.00028 21.0 0.1 0.0016 18.5 0.0 1.9 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport BAG PF02179.11 KNZ75595.1 - 4.3e-05 23.5 0.0 4.3e-05 23.5 0.0 2.5 2 1 0 2 2 2 1 BAG domain HGTP_anticodon PF03129.15 KNZ75595.1 - 0.056 13.3 1.7 0.15 12.0 1.0 1.8 1 1 0 1 1 1 0 Anticodon binding domain DUF3523 PF12037.3 KNZ75595.1 - 7.2 5.5 24.7 13 4.7 17.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DUF4328 PF14219.1 KNZ75596.1 - 0.0023 17.2 0.1 0.073 12.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4328) Syndecan PF01034.15 KNZ75596.1 - 0.0051 16.4 0.3 0.0092 15.6 0.2 1.3 1 0 0 1 1 1 1 Syndecan domain DUF202 PF02656.10 KNZ75596.1 - 0.24 11.6 2.8 0.38 11.0 0.8 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) GATase_5 PF13507.1 KNZ75597.1 - 8.5e-95 316.5 0.0 1.2e-94 316.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KNZ75597.1 - 4.2e-49 166.4 0.5 2e-26 92.8 0.1 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KNZ75597.1 - 7.6e-24 83.7 1.5 2.1e-23 82.3 0.0 2.5 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain APH PF01636.18 KNZ75599.1 - 7.6e-06 25.8 1.4 1.6e-05 24.7 0.0 2.2 2 2 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KNZ75599.1 - 0.0039 16.3 0.0 0.0063 15.7 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.20 KNZ75601.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain TFIIE_beta PF02186.10 KNZ75601.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 TFIIE beta subunit core domain RVP_2 PF08284.6 KNZ75602.1 - 0.00021 21.2 0.1 0.0033 17.3 0.0 2.2 2 1 0 2 2 2 1 Retroviral aspartyl protease Lon_C PF05362.8 KNZ75604.1 - 2.5e-64 216.3 0.5 3.9e-64 215.7 0.3 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 KNZ75604.1 - 2.1e-22 79.7 0.0 6.9e-22 78.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KNZ75604.1 - 1.1e-10 41.4 0.0 4.3e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) LON PF02190.11 KNZ75604.1 - 2.2e-09 37.3 0.0 3.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 KNZ75604.1 - 1e-06 28.2 0.0 7.4e-06 25.4 0.0 2.3 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 KNZ75604.1 - 2.6e-05 24.3 1.3 0.00018 21.5 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 KNZ75604.1 - 9.3e-05 22.4 0.0 0.00033 20.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KNZ75604.1 - 0.00011 23.0 0.0 0.00034 21.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KNZ75604.1 - 0.00016 21.5 0.1 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KNZ75604.1 - 0.00095 18.2 0.1 0.032 13.2 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 KNZ75604.1 - 0.0022 17.6 0.0 0.0054 16.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KNZ75604.1 - 0.0046 16.3 0.1 0.036 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KNZ75604.1 - 0.0079 14.9 0.1 0.026 13.2 0.1 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_18 PF13238.1 KNZ75604.1 - 0.017 15.4 0.3 0.045 14.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.1 KNZ75604.1 - 0.017 15.2 4.6 0.098 12.7 0.1 3.7 3 1 0 3 3 3 0 AAA domain AAA_19 PF13245.1 KNZ75604.1 - 0.033 13.9 0.2 0.12 12.1 0.1 2.0 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 KNZ75604.1 - 0.077 12.1 0.1 0.41 9.7 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 KNZ75604.1 - 0.083 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KNZ75604.1 - 0.11 12.1 0.1 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KNZ75604.1 - 0.13 12.5 0.3 0.88 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 KNZ75604.1 - 0.13 12.1 2.0 0.17 11.7 0.0 2.2 3 0 0 3 3 2 0 Shikimate kinase RNA_helicase PF00910.17 KNZ75604.1 - 0.13 12.3 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 KNZ75604.1 - 0.14 10.9 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 KNZ75604.1 - 0.17 11.4 0.5 0.36 10.3 0.3 1.5 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 KNZ75605.1 - 3.9e-53 180.2 0.1 5.8e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNZ75605.1 - 1.4e-13 50.4 0.0 3.1e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 KNZ75605.1 - 9.7e-06 25.1 5.9 4e-05 23.1 4.1 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ75605.1 - 4.2e-05 23.2 4.3 8.3e-05 22.3 3.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KNZ75605.1 - 0.00019 21.0 6.0 0.00043 19.9 4.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KNZ75605.1 - 0.00021 20.9 1.0 0.00021 20.9 0.7 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KNZ75605.1 - 0.0029 17.4 2.8 0.0029 17.4 1.9 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KNZ75605.1 - 0.0065 16.4 5.1 0.018 15.0 3.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KNZ75605.1 - 0.0077 16.0 0.0 0.022 14.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IBR PF01485.16 KNZ75605.1 - 0.48 10.3 4.2 0.87 9.5 1.1 2.3 2 0 0 2 2 2 0 IBR domain Cyclase PF04199.8 KNZ75606.1 - 6.3e-18 65.0 0.0 9.9e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Lactamase_B PF00753.22 KNZ75607.1 - 0.28 10.8 3.3 5.5 6.5 0.1 2.0 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily Glyco_hydro_3 PF00933.16 KNZ75608.1 - 9.7e-80 267.7 0.0 1.3e-79 267.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KNZ75608.1 - 3.6e-60 203.3 0.0 9.1e-60 201.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KNZ75608.1 - 3.3e-19 68.5 0.0 5.7e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Ser_hydrolase PF06821.8 KNZ75608.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Glyco_hydro_3 PF00933.16 KNZ75609.1 - 1.7e-82 276.7 0.0 2.4e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KNZ75609.1 - 6.1e-56 189.4 0.1 2e-55 187.7 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain adh_short PF00106.20 KNZ75610.1 - 7.1e-23 81.3 0.0 1.3e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ75610.1 - 5.9e-19 68.7 0.1 1.1e-18 67.9 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ75610.1 - 5.2e-10 39.2 0.0 1.2e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KNZ75610.1 - 4.3e-07 30.1 0.0 3.9e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KNZ75610.1 - 3.1e-05 23.5 0.0 5.3e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KNZ75610.1 - 0.0017 18.0 0.4 0.22 11.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 KNZ75610.1 - 0.014 14.2 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain YjeF_N PF03853.10 KNZ75610.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF4503 PF14951.1 KNZ75610.1 - 0.024 12.8 0.0 0.051 11.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4503) Polysacc_synt_2 PF02719.10 KNZ75610.1 - 0.031 13.1 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 KNZ75610.1 - 0.09 12.4 0.2 0.19 11.3 0.0 1.6 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Virul_Fac PF10139.4 KNZ75610.1 - 0.14 10.0 0.0 0.19 9.6 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor Lactamase_B PF00753.22 KNZ75611.1 - 5.2e-07 29.5 1.8 1.1e-06 28.3 1.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KNZ75611.1 - 0.00088 18.8 0.1 0.0011 18.5 0.1 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain UQ_con PF00179.21 KNZ75612.1 - 2.5e-41 140.4 0.0 3.9e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PEMT PF04191.8 KNZ75613.1 - 1.2e-29 102.4 2.6 2.4e-29 101.5 1.4 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase ABC1 PF03109.11 KNZ75615.1 - 5.6e-24 84.4 0.0 9.6e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RRM_1 PF00076.17 KNZ75617.1 - 5.4e-25 86.8 0.2 5.4e-16 57.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ75617.1 - 2.7e-20 72.1 0.0 4.6e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ75617.1 - 4.2e-10 39.3 0.0 2e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 KNZ75618.1 - 3.5e-78 263.2 20.9 4.2e-78 262.9 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ75618.1 - 6.3e-22 77.7 39.2 1.2e-15 57.1 6.2 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KNZ75618.1 - 0.0015 16.7 0.5 0.0015 16.7 0.3 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF3040 PF11239.3 KNZ75618.1 - 0.69 9.9 3.1 1 9.4 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Methyltransf_16 PF10294.4 KNZ75619.1 - 0.016 14.6 0.1 0.023 14.1 0.1 1.3 1 1 0 1 1 1 0 Putative methyltransferase DUF1902 PF08972.6 KNZ75619.1 - 0.091 12.3 0.1 6.3 6.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) Peroxidase_2 PF01328.12 KNZ75620.1 - 1.8e-15 56.4 0.0 6.6e-14 51.2 0.0 2.2 2 1 0 2 2 2 2 Peroxidase, family 2 DUF605 PF04652.11 KNZ75621.1 - 8.9 5.5 11.9 2.1 7.6 4.8 1.9 2 0 0 2 2 2 0 Vta1 like OTU PF02338.14 KNZ75622.1 - 0.18 12.4 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 OTU-like cysteine protease DUF605 PF04652.11 KNZ75623.1 - 2 7.7 11.1 1.3 8.3 4.0 2.1 2 0 0 2 2 2 0 Vta1 like Ank_2 PF12796.2 KNZ75624.1 - 2.7e-83 274.4 29.1 7.6e-25 87.0 0.9 4.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ75624.1 - 1.8e-63 207.3 22.0 6.5e-11 41.4 0.4 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KNZ75624.1 - 9.5e-56 184.5 34.7 1.6e-15 56.7 0.7 6.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KNZ75624.1 - 7.2e-51 169.7 20.0 3.5e-12 46.4 0.7 7.3 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ75624.1 - 6.1e-45 146.7 18.8 4.1e-06 26.5 0.1 8.5 8 0 0 8 8 8 6 Ankyrin repeat ATP_bind_1 PF03029.12 KNZ75626.1 - 0.012 15.1 0.1 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF1801 PF08818.6 KNZ75626.1 - 0.057 13.5 0.1 4.4 7.4 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DU1801) RVP_2 PF08284.6 KNZ75631.1 - 0.0008 19.3 0.0 0.00096 19.1 0.0 1.3 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KNZ75631.1 - 0.00092 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ75631.1 - 0.0056 17.1 0.0 0.0069 16.8 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease WD40 PF00400.27 KNZ75632.1 - 4.2e-10 39.1 14.9 1.1e-05 25.0 0.0 7.4 8 1 0 8 8 8 3 WD domain, G-beta repeat eIF2A PF08662.6 KNZ75632.1 - 1.1e-06 28.4 0.0 2 8.1 0.0 5.6 3 2 0 5 5 5 2 Eukaryotic translation initiation factor eIF2A Inh PF02974.9 KNZ75632.1 - 0.0012 18.3 0.2 5.6 6.6 0.0 3.9 4 0 0 4 4 4 2 Protease inhibitor Inh Abhydrolase_6 PF12697.2 KNZ75633.1 - 5.9e-15 55.7 0.0 6.5e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ75633.1 - 7.4e-06 25.7 0.0 8.4e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ75633.1 - 2.5e-05 23.9 0.0 3.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M41 PF01434.13 KNZ75634.1 - 5.6e-71 238.3 0.0 8.2e-71 237.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KNZ75634.1 - 2.9e-42 144.0 0.0 5.7e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KNZ75634.1 - 3e-09 37.0 0.0 9e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular TIP49 PF06068.8 KNZ75634.1 - 0.0019 16.9 0.0 0.0031 16.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 KNZ75634.1 - 0.003 17.6 0.1 0.22 11.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNZ75634.1 - 0.0036 17.0 0.3 0.011 15.4 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KNZ75634.1 - 0.011 15.7 2.1 0.24 11.3 0.1 3.3 3 1 1 4 4 3 0 AAA ATPase domain AAA_17 PF13207.1 KNZ75634.1 - 0.011 16.4 0.0 0.037 14.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KNZ75634.1 - 0.033 13.5 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 KNZ75634.1 - 0.038 13.0 0.0 0.09 11.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 KNZ75634.1 - 0.046 12.7 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KNZ75634.1 - 0.048 13.3 0.0 0.2 11.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KNZ75634.1 - 0.057 12.8 0.4 0.17 11.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KNZ75634.1 - 0.075 12.9 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Atrophin-1 PF03154.10 KNZ75634.1 - 0.4 8.7 16.7 0.91 7.5 10.9 1.8 2 0 0 2 2 2 0 Atrophin-1 family DUF605 PF04652.11 KNZ75634.1 - 0.59 9.4 22.5 0.89 8.8 15.6 1.1 1 0 0 1 1 1 0 Vta1 like AvrE PF11725.3 KNZ75634.1 - 0.68 6.8 6.3 0.91 6.4 4.4 1.0 1 0 0 1 1 1 0 Pathogenicity factor Plasmodium_Vir PF05795.6 KNZ75634.1 - 0.76 8.9 3.9 1.4 8.0 2.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Neur_chan_memb PF02932.11 KNZ75634.1 - 2.1 8.2 6.7 3.5 7.4 4.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MFS_1 PF07690.11 KNZ75635.1 - 2.4e-28 98.9 31.1 2.4e-28 98.9 21.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 KNZ75635.1 - 1.5e-05 24.3 4.2 3.2e-05 23.3 2.9 1.5 1 0 0 1 1 1 1 Nodulin-like MMPL PF03176.10 KNZ75635.1 - 0.036 12.7 1.4 0.076 11.7 1.0 1.6 1 0 0 1 1 1 0 MMPL family UreD PF01774.12 KNZ75636.1 - 2.5e-30 105.5 0.0 3.2e-23 82.3 0.0 2.0 1 1 1 2 2 2 2 UreD urease accessory protein NRDE-2 PF08424.5 KNZ75638.1 - 4.8e-51 173.5 0.4 8.9e-51 172.6 0.3 1.4 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KNZ75638.1 - 0.088 13.4 4.6 67 4.5 0.0 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat UPF0113 PF03657.8 KNZ75639.1 - 6.4e-09 35.6 0.0 8.4e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Sec39 PF08314.6 KNZ75640.1 - 8.1e-67 225.7 0.0 1e-66 225.3 0.0 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Transposase_22 PF02994.9 KNZ75641.1 - 0.094 11.1 0.0 0.17 10.3 0.0 1.3 1 0 0 1 1 1 0 L1 transposable element Cgr1 PF03879.9 KNZ75642.1 - 3.5e-22 78.6 18.3 4e-22 78.4 12.7 1.0 1 0 0 1 1 1 1 Cgr1 family DUF2570 PF10828.3 KNZ75642.1 - 0.052 13.1 4.2 0.067 12.8 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Remorin_C PF03763.8 KNZ75642.1 - 0.17 11.4 17.7 0.25 10.9 12.3 1.2 1 0 0 1 1 1 0 Remorin, C-terminal region Ribosomal_L27e PF01777.13 KNZ75642.1 - 0.33 11.0 3.7 0.45 10.6 2.3 1.3 1 1 0 1 1 1 0 Ribosomal L27e protein family APG6 PF04111.7 KNZ75642.1 - 0.36 9.8 7.3 0.39 9.7 5.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2514 PF10721.4 KNZ75642.1 - 0.4 10.3 11.6 0.49 10.0 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) OmpH PF03938.9 KNZ75642.1 - 1.3 8.9 10.4 1.5 8.7 7.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Herpes_DNAp_acc PF04929.7 KNZ75642.1 - 3 6.7 6.7 3.3 6.5 4.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Oxysterol_BP PF01237.13 KNZ75642.1 - 4.1 5.7 7.4 4.4 5.6 5.2 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein Macoilin PF09726.4 KNZ75642.1 - 5.8 5.0 12.4 5.9 5.0 8.6 1.1 1 0 0 1 1 1 0 Transmembrane protein RNase_H2-Ydr279 PF09468.5 KNZ75642.1 - 5.9 6.0 6.8 6.1 5.9 4.7 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Pep3_Vps18 PF05131.9 KNZ75643.1 - 4.7e-43 146.1 0.0 1e-42 145.0 0.0 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KNZ75643.1 - 1.7e-09 37.3 9.3 0.00028 20.5 0.8 4.0 3 2 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.4 KNZ75643.1 - 4.1e-06 26.9 0.1 9.6e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 KNZ75643.1 - 4.2e-05 23.2 3.4 0.00015 21.4 1.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KNZ75643.1 - 0.0013 18.4 1.4 0.0013 18.4 0.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KNZ75643.1 - 0.005 16.8 4.1 0.006 16.5 1.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNZ75643.1 - 0.012 15.2 0.9 0.14 11.8 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ75643.1 - 0.035 13.7 0.4 0.035 13.7 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1664 PF07889.7 KNZ75643.1 - 0.042 13.6 1.0 0.13 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_2 PF07719.12 KNZ75643.1 - 6.3 6.9 5.6 7.1 6.8 0.3 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat His_Phos_1 PF00300.17 KNZ75644.1 - 2.2e-19 70.1 0.0 2.7e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Reo_sigmaC PF04582.7 KNZ75645.1 - 0.001 18.3 8.4 0.001 18.3 5.8 6.5 1 1 6 7 7 7 3 Reovirus sigma C capsid protein IncA PF04156.9 KNZ75645.1 - 0.15 11.6 97.9 0.7 9.4 12.8 6.7 1 1 3 5 5 5 0 IncA protein Filament PF00038.16 KNZ75645.1 - 0.75 9.1 94.5 0.013 14.9 2.6 5.4 1 1 2 4 4 4 0 Intermediate filament protein Mito_carr PF00153.22 KNZ75646.1 - 6.5e-24 83.4 6.8 1.1e-13 50.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mpv17_PMP22 PF04117.7 KNZ75647.1 - 1.8e-11 43.5 0.9 2.8e-11 42.8 0.6 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family TRAPPC-Trs85 PF12739.2 KNZ75648.1 - 3.8e-31 108.1 0.0 2.2e-25 89.1 0.0 2.3 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.6 KNZ75648.1 - 8.8e-05 20.0 0.0 0.00013 19.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit LCCL PF03815.14 KNZ75649.1 - 7e-11 41.9 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Seipin PF06775.9 KNZ75651.1 - 1.9e-07 30.7 0.0 3.9e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 Putative adipose-regulatory protein (Seipin) SH3BGR PF04908.10 KNZ75652.1 - 1.5e-12 47.3 0.0 3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein LMWPc PF01451.16 KNZ75653.1 - 1.1e-30 106.7 0.0 1.2e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Aldedh PF00171.17 KNZ75654.1 - 3.9e-105 351.8 0.0 5.8e-105 351.2 0.0 1.3 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KNZ75654.1 - 2.6e-05 23.1 0.1 5e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Aldedh PF00171.17 KNZ75655.1 - 2.4e-126 421.8 0.1 2.7e-126 421.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KNZ75655.1 - 4.2e-05 22.4 0.0 0.0001 21.1 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Imm15 PF15590.1 KNZ75656.1 - 0.023 13.7 3.0 0.034 13.2 0.7 2.2 2 0 0 2 2 2 0 Immunity protein 15 RE_MjaI PF09568.5 KNZ75656.1 - 0.23 11.0 4.9 1.8 8.1 0.0 2.6 3 0 0 3 3 3 0 MjaI restriction endonuclease DUF1897 PF09005.5 KNZ75656.1 - 0.41 10.1 3.6 0.62 9.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) GDI PF00996.13 KNZ75657.1 - 9.8e-200 663.4 0.0 1.1e-199 663.2 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Rav1p_C PF12234.3 KNZ75658.1 - 2.3e-173 577.7 0.0 3.1e-173 577.3 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 KNZ75658.1 - 7.5e-05 22.4 0.1 0.037 13.9 0.1 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat CheB_methylest PF01339.12 KNZ75658.1 - 0.29 10.5 0.0 0.56 9.6 0.0 1.4 1 0 0 1 1 1 0 CheB methylesterase Fasciclin PF02469.17 KNZ75659.1 - 6.9e-66 220.0 0.0 2.2e-18 66.4 0.1 5.5 5 0 0 5 5 5 5 Fasciclin domain Mito_carr PF00153.22 KNZ75659.1 - 3.1e-65 215.9 5.2 6.7e-21 73.8 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF619 PF04768.8 KNZ75660.1 - 7.3e-36 123.1 0.0 1.3e-20 73.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF619) UQ_con PF00179.21 KNZ75661.1 - 1.2e-18 66.9 0.0 2.1e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SKN1 PF03935.10 KNZ75662.1 - 7.9e-174 578.5 6.9 9.4e-174 578.2 4.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SNAPc_SNAP43 PF09808.4 KNZ75663.1 - 7e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Ima1_N PF09779.4 KNZ75664.1 - 3.3e-26 92.3 1.0 4.9e-26 91.7 0.7 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain Tox-PL PF15644.1 KNZ75664.1 - 0.044 14.5 0.1 0.095 13.4 0.0 1.5 1 0 0 1 1 1 0 Papain fold toxin 1 Hepar_II_III PF07940.8 KNZ75666.1 - 9.2e-11 41.7 0.6 2e-10 40.6 0.4 1.5 1 0 0 1 1 1 1 Heparinase II/III-like protein Rick_17kDa_Anti PF05433.10 KNZ75666.1 - 0.034 13.8 0.4 0.084 12.5 0.3 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain Dec-1 PF04624.9 KNZ75666.1 - 8.6 6.0 5.7 51 3.6 0.0 2.7 2 0 0 2 2 2 0 Dec-1 repeat Thiolase_N PF00108.18 KNZ75667.1 - 7.5e-73 244.7 0.2 1.1e-72 244.1 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KNZ75667.1 - 3.7e-32 110.3 0.0 1.2e-31 108.7 0.0 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KNZ75667.1 - 1e-05 25.0 0.0 0.0021 17.7 0.0 2.6 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KNZ75667.1 - 0.00048 19.6 0.2 0.0011 18.5 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain dCMP_cyt_deam_1 PF00383.17 KNZ75668.1 - 0.06 13.0 0.1 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region SPT2 PF08243.6 KNZ75668.1 - 6 7.2 10.2 2.8 8.2 4.4 2.0 2 0 0 2 2 2 0 SPT2 chromatin protein Glyco_transf_21 PF13506.1 KNZ75670.1 - 6.7e-20 71.0 0.2 8.2e-15 54.5 0.0 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KNZ75670.1 - 2e-08 34.3 0.0 4.4e-08 33.2 0.0 1.6 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KNZ75670.1 - 0.0091 15.6 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Sec3_C PF09763.4 KNZ75671.1 - 1.9e-161 538.6 0.7 2.5e-161 538.2 0.5 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KNZ75671.1 - 4e-20 71.4 0.0 9.7e-20 70.2 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Mto2_bdg PF12808.2 KNZ75671.1 - 0.67 10.1 3.7 0.41 10.7 0.4 2.4 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region P16-Arc PF04699.9 KNZ75672.1 - 5.5e-49 166.0 0.1 6.1e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Zn_clus PF00172.13 KNZ75673.1 - 1.2e-05 25.0 8.8 2.3e-05 24.2 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KNZ75673.1 - 0.0016 17.3 0.1 0.0044 15.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1212 PF06738.7 KNZ75674.1 - 2.1e-31 108.9 1.6 2.1e-31 108.9 1.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KNZ75674.1 - 1.4e-15 57.3 10.7 1.4e-15 57.3 7.4 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3815) SNF2_N PF00176.18 KNZ75675.1 - 1.2e-66 224.5 0.0 6.8e-66 222.0 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNZ75675.1 - 7.3e-10 38.5 0.0 1.5e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KNZ75675.1 - 0.00059 19.5 0.6 0.0018 17.9 0.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.10 KNZ75675.1 - 0.0075 16.1 0.1 1.5 8.6 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 KNZ75675.1 - 0.019 14.6 0.7 0.019 14.6 0.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ75675.1 - 0.021 14.8 1.6 0.059 13.3 1.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HIRAN PF08797.6 KNZ75675.1 - 0.033 14.1 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 HIRAN domain MMR_HSR1 PF01926.18 KNZ75676.1 - 1.8e-16 60.1 0.0 7.1e-15 54.9 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KNZ75676.1 - 1e-05 24.8 0.0 7.1e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KNZ75676.1 - 5e-05 22.5 0.0 9.9e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KNZ75676.1 - 0.00031 19.9 0.0 0.00055 19.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 KNZ75676.1 - 0.007 16.1 0.1 0.021 14.6 0.1 1.8 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 KNZ75676.1 - 0.026 15.0 0.5 0.071 13.6 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein PPR_2 PF13041.1 KNZ75677.1 - 4.4e-11 42.5 0.3 0.003 17.5 0.0 6.3 6 1 1 7 7 7 2 PPR repeat family PPR PF01535.15 KNZ75677.1 - 1.7e-07 30.7 0.7 0.024 14.5 0.0 5.2 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.2 KNZ75677.1 - 3.3e-06 26.4 1.1 0.018 14.4 0.0 3.5 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.1 KNZ75677.1 - 0.00039 20.4 4.0 0.96 9.8 0.1 4.8 4 1 0 4 4 4 1 Pentatricopeptide repeat domain Ribosomal_L3 PF00297.17 KNZ75678.1 - 1.2e-120 401.8 7.2 1.4e-120 401.6 5.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 SnoaL PF07366.7 KNZ75679.1 - 5.2e-08 32.5 0.0 8.3e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KNZ75679.1 - 1e-05 25.8 0.2 2.2e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 SnoaL-like domain Bystin PF05291.6 KNZ75680.1 - 2.4e-122 407.6 0.0 3.6e-122 407.0 0.0 1.2 1 0 0 1 1 1 1 Bystin Epimerase PF01370.16 KNZ75681.1 - 5.7e-44 150.3 0.0 7.6e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KNZ75681.1 - 6.9e-11 41.5 0.0 9.5e-11 41.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KNZ75681.1 - 7.3e-11 41.2 0.0 1.1e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KNZ75681.1 - 5.1e-08 32.1 0.2 0.00054 18.9 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 KNZ75681.1 - 1.4e-06 27.4 0.3 0.0022 16.9 0.1 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KNZ75681.1 - 2.8e-05 24.2 0.0 5.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KNZ75681.1 - 0.032 14.1 0.2 0.23 11.3 0.1 2.1 2 0 0 2 2 2 0 short chain dehydrogenase DUF1205 PF06722.7 KNZ75681.1 - 0.09 13.0 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1205) Abhydrolase_6 PF12697.2 KNZ75682.1 - 4.8e-11 42.9 0.0 8.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ75682.1 - 0.01 15.4 0.1 0.2 11.1 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ75682.1 - 0.033 13.9 0.0 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2458 PF10454.4 KNZ75683.1 - 1.7e-12 47.4 0.4 2.5e-12 46.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DUF148 PF02520.12 KNZ75683.1 - 0.075 12.8 0.6 0.15 11.8 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF148 OmpH PF03938.9 KNZ75683.1 - 4.1 7.3 7.0 0.27 11.1 1.1 1.8 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) RGS PF00615.14 KNZ75684.1 - 1.2e-42 144.7 0.5 3e-42 143.4 0.4 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 KNZ75684.1 - 7.8e-16 57.5 0.0 2.2e-07 30.5 0.0 2.9 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HTH_45 PF14947.1 KNZ75684.1 - 0.07 12.9 0.1 4 7.3 0.0 3.1 3 0 0 3 3 3 0 Winged helix-turn-helix Cyt-b5 PF00173.23 KNZ75685.1 - 4.9e-12 45.4 0.0 8.5e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2188 PF09954.4 KNZ75685.1 - 4.1 7.4 6.1 11 5.9 0.6 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Nup160 PF11715.3 KNZ75687.1 - 4.5e-29 100.9 0.1 6.2e-18 64.2 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Fungal_trans PF04082.13 KNZ75688.1 - 5.1e-20 71.4 1.7 8.2e-20 70.7 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ75688.1 - 2.5e-05 24.0 9.4 4.3e-05 23.3 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2263 PF10021.4 KNZ75689.1 - 9.5e-35 119.7 0.0 1.3e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) VSP PF03302.8 KNZ75690.1 - 2.7e-08 32.8 102.2 0.00036 19.2 11.2 5.9 1 1 4 5 5 5 4 Giardia variant-specific surface protein GF_recep_IV PF14843.1 KNZ75690.1 - 0.0011 18.5 89.9 0.0021 17.6 17.6 3.9 1 1 1 3 3 3 2 Growth factor receptor domain IV Fer4_3 PF12798.2 KNZ75690.1 - 0.039 14.5 2.0 0.039 14.5 1.4 9.8 11 2 0 11 11 11 0 4Fe-4S binding domain DUF4381 PF14316.1 KNZ75690.1 - 0.056 13.5 0.2 0.084 12.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Vpu PF00558.14 KNZ75690.1 - 0.83 9.2 2.2 0.82 9.2 0.4 1.7 2 0 0 2 2 2 0 Vpu protein Furin-like PF00757.15 KNZ75690.1 - 7 6.2 87.7 0.065 12.8 22.0 4.7 1 1 3 4 4 4 0 Furin-like cysteine rich region TPR_11 PF13414.1 KNZ75691.1 - 2.4e-55 184.0 24.1 1.7e-15 56.4 0.6 6.3 5 1 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 KNZ75691.1 - 5.3e-41 136.6 20.9 6.7e-05 22.3 0.7 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ75691.1 - 9.7e-36 118.8 26.4 0.00016 21.2 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ75691.1 - 1.5e-22 79.6 16.7 7.7e-07 29.6 0.0 6.3 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ75691.1 - 3.8e-22 78.0 22.4 4.3e-13 48.9 0.4 6.8 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ75691.1 - 3.1e-17 61.5 17.5 0.071 13.7 0.1 8.6 5 3 5 10 10 9 5 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ75691.1 - 1.3e-15 55.8 8.3 0.001 18.6 0.1 7.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ75691.1 - 1.7e-15 57.0 16.0 1e-09 38.5 0.2 6.9 3 2 4 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ75691.1 - 2.8e-15 55.1 7.5 0.0045 17.0 0.1 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ75691.1 - 4e-15 54.3 23.8 0.0005 19.6 0.0 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ75691.1 - 7.7e-08 32.3 16.0 0.95 10.0 0.0 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat Apc3 PF12895.2 KNZ75691.1 - 9.7e-08 32.0 13.8 0.00037 20.5 0.9 5.7 3 1 3 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KNZ75691.1 - 3.1e-06 26.9 6.3 0.15 11.9 0.0 5.7 4 3 2 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ75691.1 - 0.0014 18.4 11.8 0.0026 17.6 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.12 KNZ75691.1 - 0.015 15.5 7.5 24 5.2 0.0 4.4 4 0 0 4 4 4 0 Bacterial transcriptional activator domain PPR PF01535.15 KNZ75691.1 - 0.023 14.6 0.4 20 5.4 0.0 4.6 4 1 0 4 4 4 0 PPR repeat TPR_4 PF07721.9 KNZ75691.1 - 0.023 15.0 0.0 0.7 10.4 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF357 PF04010.8 KNZ75691.1 - 0.048 13.3 4.8 0.042 13.5 0.7 2.9 2 1 1 3 3 2 0 Protein of unknown function (DUF357) XPC-binding PF09280.6 KNZ75691.1 - 0.069 12.6 3.7 0.82 9.1 0.5 2.7 2 0 0 2 2 2 0 XPC-binding domain TPR_20 PF14561.1 KNZ75691.1 - 0.076 13.1 12.2 2.3 8.4 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 KNZ75691.1 - 0.078 12.7 21.3 1.5 8.6 0.0 5.9 7 0 0 7 7 5 0 Tetratricopeptide repeat Strep_SA_rep PF06696.6 KNZ75691.1 - 0.13 12.0 0.3 0.13 12.0 0.2 3.1 3 0 0 3 3 3 0 Streptococcal surface antigen repeat DUF1180 PF06679.7 KNZ75691.1 - 0.21 11.4 1.8 0.54 10.1 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) MIT PF04212.13 KNZ75691.1 - 3.1 7.7 23.6 7.3 6.5 0.5 7.0 6 2 0 6 6 6 0 MIT (microtubule interacting and transport) domain Adap_comp_sub PF00928.16 KNZ75692.1 - 5.8e-51 173.1 0.0 8.2e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KNZ75692.1 - 3.2e-05 23.6 0.0 6.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldo_ket_red PF00248.16 KNZ75693.1 - 4e-40 137.4 0.0 5.1e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family B12D PF06522.6 KNZ75694.1 - 3.6e-11 42.5 0.1 4.6e-11 42.2 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit ESSS PF10183.4 KNZ75694.1 - 0.13 12.6 0.1 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DivIC PF04977.10 KNZ75695.1 - 2.7 7.5 5.7 29 4.2 1.5 2.5 2 0 0 2 2 2 0 Septum formation initiator Isochorismatase PF00857.15 KNZ75696.1 - 2e-15 57.1 0.0 1.3e-14 54.5 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family Glyco_hydro_3 PF00933.16 KNZ75698.1 - 4e-62 209.8 0.0 6.4e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KNZ75698.1 - 1.2e-26 93.6 0.2 2.2e-26 92.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain rve PF00665.21 KNZ75698.1 - 1.1e-06 28.7 0.0 2.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain UPF0147 PF03685.8 KNZ75699.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) SAGA-Tad1 PF12767.2 KNZ75700.1 - 0.035 13.7 7.3 0.052 13.2 5.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Herpes_Helicase PF02689.9 KNZ75701.1 - 7.3e-08 30.6 0.0 8.3e-08 30.4 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ75701.1 - 0.00094 19.2 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Glyco_hydro_3 PF00933.16 KNZ75702.1 - 1.4e-64 217.9 0.0 2.2e-64 217.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KNZ75702.1 - 1.8e-52 178.1 0.2 3e-52 177.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KNZ75702.1 - 0.00034 20.4 0.0 0.00075 19.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DDR PF08841.5 KNZ75702.1 - 0.088 11.6 1.4 0.15 10.8 0.9 1.3 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Helitron_like_N PF14214.1 KNZ75703.1 - 7.6e-59 198.5 0.2 9e-59 198.2 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 KNZ75703.1 - 0.0053 15.5 0.1 0.006 15.3 0.1 1.2 1 0 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) DUF3584 PF12128.3 KNZ75705.1 - 0.0017 15.8 33.0 0.0023 15.3 22.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) FUSC PF04632.7 KNZ75705.1 - 4.6 5.5 12.6 7.5 4.8 8.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.6 KNZ75705.1 - 9.3 4.7 32.1 1.4 7.5 16.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Glyco_hydro_47 PF01532.15 KNZ75707.1 - 1.6e-139 465.4 0.3 1.9e-139 465.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 C5-epim_C PF06662.8 KNZ75707.1 - 0.015 14.6 0.3 1 8.6 0.0 3.3 3 1 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus MS_channel PF00924.13 KNZ75707.1 - 0.16 11.2 0.0 2.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel Chs3p PF12271.3 KNZ75708.1 - 1.1e-114 382.3 22.7 1.3e-114 382.1 15.7 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit PS_Dcarbxylase PF02666.10 KNZ75709.1 - 4.5e-76 254.6 0.0 1.1e-74 250.1 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase SPO22 PF08631.5 KNZ75710.1 - 8.9e-19 67.6 0.6 8.9e-19 67.6 0.4 3.1 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like Apc3 PF12895.2 KNZ75710.1 - 3e-05 24.0 0.3 0.31 11.2 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KNZ75710.1 - 0.00032 20.9 3.2 0.027 14.7 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ75710.1 - 0.0028 17.5 1.4 5.8 6.9 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ75710.1 - 0.0065 16.1 0.9 6.7 6.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ75710.1 - 0.014 16.0 9.1 0.12 13.1 0.2 5.3 5 2 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ75710.1 - 0.029 14.8 0.3 11 6.6 0.2 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ75710.1 - 0.047 14.3 0.3 0.047 14.3 0.2 6.8 9 1 1 10 10 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ75710.1 - 0.32 10.9 13.2 0.79 9.7 0.1 5.9 4 3 3 7 7 7 0 Tetratricopeptide repeat PPR_3 PF13812.1 KNZ75710.1 - 0.32 11.3 5.3 10 6.7 0.0 5.2 5 0 0 5 5 4 0 Pentatricopeptide repeat domain TPR_2 PF07719.12 KNZ75710.1 - 0.44 10.5 11.1 4.6 7.4 0.1 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KNZ75710.1 - 0.63 10.6 5.7 0.3 11.6 0.4 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat Cullin PF00888.17 KNZ75711.1 - 2.3e-98 330.2 1.4 3.3e-98 329.7 1.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KNZ75711.1 - 2.9e-23 81.4 0.1 1.1e-22 79.5 0.1 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain TRAPP PF04051.11 KNZ75712.1 - 2.9e-29 101.5 0.0 4.3e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF3235 PF11574.3 KNZ75712.1 - 0.031 14.5 0.0 0.079 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) DUF3752 PF12572.3 KNZ75713.1 - 2.4e-37 128.3 3.5 2.4e-37 128.3 2.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) UBN2_2 PF14227.1 KNZ75715.1 - 0.034 13.6 0.1 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF3627 PF12299.3 KNZ75715.1 - 0.17 11.9 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) Abhydrolase_1 PF00561.15 KNZ75716.1 - 5.6e-34 117.6 0.0 1.9e-33 115.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KNZ75716.1 - 4.2e-10 39.8 0.4 1.6e-09 37.9 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Rgp1 PF08737.5 KNZ75718.1 - 1.4e-46 159.3 0.0 2.6e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.17 KNZ75718.1 - 0.011 15.8 0.0 4.6 7.3 0.0 3.2 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain p450 PF00067.17 KNZ75719.1 - 4.7e-42 144.0 0.0 5.4e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rapsyn_N PF10579.4 KNZ75719.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region A_deaminase PF00962.17 KNZ75720.1 - 2.7e-24 85.7 0.0 4e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase F-box-like PF12937.2 KNZ75721.1 - 3.3e-05 23.5 0.1 0.00011 21.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ75721.1 - 0.0018 17.8 0.2 0.0059 16.2 0.1 1.9 1 0 0 1 1 1 1 F-box domain Tryp_alpha_amyl PF00234.17 KNZ75721.1 - 0.087 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Protease inhibitor/seed storage/LTP family COesterase PF00135.23 KNZ75722.1 - 6.5e-81 272.6 0.0 7.4e-73 246.0 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ75722.1 - 4.4e-10 39.4 0.1 3.8e-09 36.4 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ75722.1 - 1.6e-05 24.6 0.0 4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ75722.1 - 0.021 14.0 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KNZ75722.1 - 0.025 14.4 0.1 0.064 13.1 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.20 KNZ75723.1 - 6.1e-32 110.8 0.1 8.4e-32 110.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ75723.1 - 6.6e-24 84.9 0.3 4.9e-23 82.1 0.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ75723.1 - 2.3e-15 56.6 0.1 3.7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KNZ75723.1 - 0.0048 16.5 1.3 0.0075 15.9 0.9 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KNZ75723.1 - 0.02 14.2 0.2 0.032 13.6 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 KNZ75723.1 - 0.06 13.3 0.5 0.25 11.3 0.2 2.0 2 0 0 2 2 2 0 TrkA-N domain AdoHcyase_NAD PF00670.16 KNZ75723.1 - 0.064 13.1 1.2 0.12 12.2 0.8 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Adeno_E3_CR2 PF02439.10 KNZ75725.1 - 0.1 12.1 1.8 0.17 11.4 1.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 UBN2_2 PF14227.1 KNZ75726.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ75726.1 - 0.022 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 KNZ75726.1 - 0.063 12.7 2.4 0.075 12.4 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) SKG6 PF08693.5 KNZ75728.1 - 0.0068 15.7 0.1 0.012 14.9 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PDGLE PF13190.1 KNZ75728.1 - 0.065 12.9 0.0 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 PDGLE domain Bromodomain PF00439.20 KNZ75729.1 - 1.5e-22 79.3 0.0 2.6e-15 56.1 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 KNZ75729.1 - 2.1e-09 37.1 0.0 3.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 BAH domain zf-C2H2 PF00096.21 KNZ75730.1 - 1.8e-08 34.1 8.5 2.9e-05 24.1 0.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KNZ75730.1 - 2e-06 27.7 0.5 2e-06 27.7 0.4 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KNZ75730.1 - 0.00079 19.5 6.1 0.17 12.2 0.6 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KNZ75730.1 - 0.0032 17.5 0.3 1.2 9.3 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KNZ75730.1 - 0.012 15.2 1.7 0.012 15.2 1.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 KNZ75730.1 - 0.042 13.6 1.7 0.078 12.7 0.6 1.9 1 1 1 2 2 2 0 BED zinc finger zf-met PF12874.2 KNZ75730.1 - 0.21 11.8 1.3 9.2 6.6 0.0 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Shisa PF13908.1 KNZ75730.1 - 9.7 6.3 10.1 0.51 10.5 0.3 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Caleosin PF05042.8 KNZ75732.1 - 6.2e-44 149.6 0.0 7.7e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein adh_short PF00106.20 KNZ75733.1 - 1.2e-07 31.8 0.0 2.7e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KNZ75733.1 - 0.0048 15.8 0.0 0.008 15.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein KR PF08659.5 KNZ75733.1 - 0.025 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 KR domain Epimerase PF01370.16 KNZ75733.1 - 0.075 12.4 0.1 0.72 9.2 0.0 2.4 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family FKBP_C PF00254.23 KNZ75734.1 - 4.3e-32 110.0 0.0 5e-32 109.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Peptidase_S24 PF00717.18 KNZ75734.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase S24-like Glyco_transf_25 PF01755.12 KNZ75735.1 - 1.1e-05 25.1 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) OPT PF03169.10 KNZ75736.1 - 1.4e-152 509.3 63.0 2.2e-128 429.4 34.0 3.3 2 1 0 2 2 2 2 OPT oligopeptide transporter protein GTPase_Cys_C PF12631.2 KNZ75737.1 - 0.0041 17.4 0.7 0.018 15.4 0.5 1.9 1 1 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF2570 PF10828.3 KNZ75737.1 - 0.022 14.3 2.9 0.022 14.3 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF4085 PF13315.1 KNZ75737.1 - 0.25 10.6 4.7 0.3 10.4 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) DUF1796 PF08795.5 KNZ75737.1 - 0.43 10.2 4.7 0.23 11.1 1.2 1.8 1 1 1 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) APG6 PF04111.7 KNZ75737.1 - 9.1 5.2 14.0 12 4.8 9.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 GFA PF04828.9 KNZ75738.1 - 1.7e-34 117.6 0.5 2.2e-22 78.8 0.4 2.2 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 KNZ75738.1 - 0.033 14.0 2.5 11 5.9 0.0 2.8 2 1 0 2 2 2 0 Double zinc ribbon OTT_1508_deam PF14441.1 KNZ75740.1 - 0.00027 20.7 0.1 0.00046 20.0 0.1 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase DYW_deaminase PF14432.1 KNZ75740.1 - 0.0023 17.9 0.1 0.026 14.5 0.1 2.2 2 0 0 2 2 2 1 DYW family of nucleic acid deaminases Sua5_yciO_yrdC PF01300.13 KNZ75740.1 - 0.12 11.5 0.0 1.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Telomere recombination TMEM154 PF15102.1 KNZ75742.1 - 0.046 13.4 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family AA_permease_2 PF13520.1 KNZ75743.1 - 7.5e-44 149.9 53.4 8.6e-44 149.7 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KNZ75743.1 - 3.5e-08 32.2 47.2 5.4e-08 31.6 32.7 1.3 1 0 0 1 1 1 1 Amino acid permease PIF1 PF05970.9 KNZ75746.1 - 2.2e-39 135.4 0.0 2.8e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ75746.1 - 0.0085 15.6 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KNZ75746.1 - 0.0091 15.8 0.0 0.022 14.6 0.0 1.6 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KNZ75746.1 - 0.012 15.0 0.1 0.031 13.7 0.1 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KNZ75746.1 - 0.075 13.2 0.1 0.43 10.7 0.1 2.2 1 1 0 1 1 1 0 RNA helicase Torsin PF06309.6 KNZ75746.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin Herpes_Helicase PF02689.9 KNZ75747.1 - 2e-05 22.5 0.1 2e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Helicase Rubella_Capsid PF05750.6 KNZ75750.1 - 0.13 11.6 2.0 0.19 11.0 1.4 1.2 1 0 0 1 1 1 0 Rubella capsid protein DnaJ PF00226.26 KNZ75751.1 - 9.1e-20 70.1 1.0 2e-19 69.0 0.0 2.2 3 0 0 3 3 2 1 DnaJ domain TPR_11 PF13414.1 KNZ75751.1 - 5.6e-17 61.1 3.1 1.6e-11 43.6 0.0 4.4 5 0 0 5 5 3 2 TPR repeat TPR_2 PF07719.12 KNZ75751.1 - 1.9e-15 55.4 0.5 0.00013 21.5 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ75751.1 - 8.9e-13 47.2 0.0 0.00019 20.9 0.0 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ75751.1 - 1.6e-11 43.7 6.8 0.0034 17.8 0.1 6.7 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ75751.1 - 1.3e-09 38.4 14.7 3.2e-05 24.4 0.2 5.3 5 2 2 7 7 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ75751.1 - 4.4e-08 32.7 0.3 0.03 14.5 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ75751.1 - 3.7e-07 30.3 6.6 0.014 15.6 0.2 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ75751.1 - 5e-07 29.0 1.4 0.016 14.9 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KNZ75751.1 - 2e-06 27.8 0.2 0.021 14.9 0.0 4.1 4 1 1 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KNZ75751.1 - 6.9e-06 26.1 0.8 5.4 7.6 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 KNZ75751.1 - 1.3e-05 25.1 5.1 0.87 10.2 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ75751.1 - 2.2e-05 23.8 0.0 0.16 11.8 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ75751.1 - 6.1e-05 22.8 5.0 0.5 10.3 0.0 4.4 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ75751.1 - 0.00071 19.3 4.8 0.85 9.5 0.1 5.1 3 1 2 5 5 5 1 Tetratricopeptide repeat L27_N PF09060.5 KNZ75751.1 - 0.022 14.5 0.1 0.053 13.3 0.1 1.6 1 0 0 1 1 1 0 L27_N BTAD PF03704.12 KNZ75751.1 - 0.058 13.6 3.2 3 8.1 0.0 4.1 4 1 0 4 4 4 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 KNZ75751.1 - 0.55 10.2 5.8 4.7 7.2 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat OTT_1508_deam PF14441.1 KNZ75752.1 - 2.1e-09 37.3 0.2 4e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase DYW_deaminase PF14432.1 KNZ75752.1 - 1.7 8.6 5.0 11 6.0 2.3 2.7 2 1 0 2 2 2 0 DYW family of nucleic acid deaminases DUF4632 PF15451.1 KNZ75752.1 - 2.8 7.9 4.5 2.8 7.9 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) OTT_1508_deam PF14441.1 KNZ75753.1 - 0.00025 20.8 0.2 0.00055 19.7 0.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase DYW_deaminase PF14432.1 KNZ75753.1 - 0.11 12.4 0.2 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases DUF4182 PF13790.1 KNZ75753.1 - 0.52 10.1 4.0 16 5.3 1.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4182) Cu-oxidase PF00394.17 KNZ75754.1 - 2.3e-49 167.3 0.1 9.8e-48 162.0 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KNZ75754.1 - 2e-32 111.6 0.1 5.2e-32 110.2 0.0 1.6 2 0 0 2 2 2 1 Multicopper oxidase ChitinaseA_N PF08329.5 KNZ75754.1 - 0.089 12.5 0.0 0.27 11.0 0.0 1.8 1 1 0 1 1 1 0 Chitinase A, N-terminal domain Cu-oxidase_3 PF07732.10 KNZ75754.1 - 0.11 12.2 0.1 70 3.1 0.0 3.5 3 0 0 3 3 3 0 Multicopper oxidase Glyco_hydro_31 PF01055.21 KNZ75758.1 - 9.6e-150 499.2 5.4 1.7e-149 498.3 3.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KNZ75758.1 - 2.4e-16 59.3 0.0 7.2e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like Gb3_synth PF04572.7 KNZ75758.1 - 0.026 14.1 0.5 0.067 12.8 0.4 1.6 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region MFS_1 PF07690.11 KNZ75759.1 - 2.5e-30 105.3 9.6 2.6e-30 105.3 6.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ75759.1 - 3.6e-10 38.9 12.2 5e-10 38.5 8.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KNZ75759.1 - 2.1e-07 29.5 2.7 2.6e-07 29.2 1.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KNZ75759.1 - 0.00021 19.8 0.2 0.00083 17.8 0.2 1.8 1 1 0 1 1 1 1 MFS/sugar transport protein EthD PF07110.6 KNZ75760.1 - 0.017 16.0 0.1 0.054 14.4 0.1 2.0 1 1 0 1 1 1 0 EthD domain SelB-wing_3 PF09107.6 KNZ75760.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix DUF4286 PF14114.1 KNZ75760.1 - 0.11 12.8 0.7 0.14 12.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) FTSW_RODA_SPOVE PF01098.14 KNZ75763.1 - 0.025 13.3 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 Cell cycle protein SKN1 PF03935.10 KNZ75764.1 - 1.4e-172 574.3 7.4 3.7e-171 569.6 5.1 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 KNZ75764.1 - 2.2e-05 23.8 0.0 0.00049 19.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Sigma_reg_N PF13800.1 KNZ75764.1 - 0.17 11.9 0.1 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DSPc PF00782.15 KNZ75765.1 - 3.1e-30 104.4 0.0 3.7e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KNZ75765.1 - 2.3e-05 23.8 0.0 2.8e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KNZ75765.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 KNZ75765.1 - 0.042 13.9 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF3403 PF11883.3 KNZ75767.1 - 0.0094 16.2 0.3 0.029 14.6 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3403) TPK_B1_binding PF04265.9 KNZ75769.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain DnaJ PF00226.26 KNZ75770.1 - 4.4e-12 45.5 0.0 8.4e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Init_tRNA_PT PF04179.7 KNZ75771.1 - 4.7e-109 365.2 0.0 7.9e-109 364.5 0.0 1.3 1 1 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase SET PF00856.23 KNZ75772.1 - 1.6e-12 48.0 0.0 1.1e-11 45.2 0.0 2.0 1 1 0 1 1 1 1 SET domain SAF PF08666.7 KNZ75772.1 - 0.013 15.8 0.0 5.2 7.5 0.0 2.4 2 0 0 2 2 2 0 SAF domain Pro_Al_protease PF02983.9 KNZ75772.1 - 0.082 12.8 0.0 7.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Alpha-lytic protease prodomain Calpain_III PF01067.17 KNZ75773.1 - 1.7e-21 76.3 0.0 1.4e-08 34.5 0.0 4.7 3 2 1 4 4 4 4 Calpain large subunit, domain III Peptidase_C2 PF00648.16 KNZ75773.1 - 2.9e-07 29.7 0.0 5.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 KNZ75773.1 - 0.013 15.4 1.0 0.021 14.6 0.7 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.20 KNZ75774.1 - 6.3e-12 45.2 0.1 1.1e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KNZ75774.1 - 0.00011 21.2 0.1 0.0004 19.5 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KNZ75774.1 - 0.00012 21.2 0.1 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ75774.1 - 0.0023 17.7 0.0 0.012 15.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF793 PF05633.6 KNZ75776.1 - 0.0051 15.6 0.0 0.0091 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF793) DUF641 PF04859.7 KNZ75776.1 - 0.065 13.0 1.9 0.19 11.4 0.7 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Fmp27_WPPW PF10359.4 KNZ75776.1 - 0.094 11.1 0.6 0.14 10.5 0.5 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain KLRAQ PF10205.4 KNZ75776.1 - 0.1 12.6 2.5 0.24 11.4 1.4 1.9 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein PEP-utilisers_N PF05524.8 KNZ75776.1 - 1.3 8.7 9.1 1.8 8.3 0.5 3.3 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal DUF1925 PF09094.6 KNZ75777.1 - 0.15 12.0 0.3 0.75 9.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) Fib_alpha PF08702.5 KNZ75777.1 - 0.87 9.7 5.4 0.29 11.2 0.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Pkinase PF00069.20 KNZ75779.1 - 9e-13 47.9 0.0 5.2e-10 38.9 0.0 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ75779.1 - 5.5e-05 22.3 0.0 0.0036 16.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Seadorna_VP7 PF07387.6 KNZ75779.1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 KNZ75780.1 - 3.5e-12 46.0 0.0 7.6e-10 38.3 0.0 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ75780.1 - 1e-05 24.7 0.0 0.001 18.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase 2OG-FeII_Oxy PF03171.15 KNZ75784.1 - 8.2e-14 51.7 0.2 6.6e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KNZ75784.1 - 2e-13 50.9 0.8 3.8e-13 49.9 0.1 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Zn_clus PF00172.13 KNZ75785.1 - 0.012 15.5 5.1 0.15 12.0 0.9 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain L27 PF02828.11 KNZ75786.1 - 0.11 12.2 0.2 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 L27 domain DUF3602 PF12223.3 KNZ75789.1 - 1.6e-24 86.1 40.6 3.6e-05 24.0 1.5 6.3 2 1 4 6 6 6 6 Protein of unknown function (DUF3602) DUF3381 PF11861.3 KNZ75792.1 - 0.098 12.1 0.1 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) UPF0147 PF03685.8 KNZ75793.1 - 0.052 13.4 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Oxidored_FMN PF00724.15 KNZ75794.1 - 9.1e-20 70.9 0.0 1.1e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DIOX_N PF14226.1 KNZ75795.1 - 3e-19 69.6 0.0 5.4e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KNZ75795.1 - 1.5e-12 47.6 0.2 1.2e-11 44.7 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Tautomerase PF01361.16 KNZ75795.1 - 0.086 12.4 0.0 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 Tautomerase enzyme Lge1 PF11488.3 KNZ75796.1 - 0.019 15.1 0.9 0.019 15.1 0.6 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 ERM PF00769.14 KNZ75796.1 - 0.019 14.4 9.6 0.052 13.0 6.6 1.7 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3287 PF11690.3 KNZ75796.1 - 0.21 11.6 4.1 0.29 11.2 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) APG6 PF04111.7 KNZ75796.1 - 1.8 7.5 3.9 2.6 7.0 2.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 NTR2 PF15458.1 KNZ75796.1 - 2.9 7.0 8.7 0.048 12.9 0.9 1.9 2 0 0 2 2 2 0 Nineteen complex-related protein 2 Striatin PF08232.7 KNZ75796.1 - 3.9 7.7 13.7 0.12 12.7 3.6 2.5 2 0 0 2 2 2 0 Striatin family DAHP_synth_2 PF01474.11 KNZ75798.1 - 5.1e-173 575.4 0.0 5.8e-173 575.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family GST_N_3 PF13417.1 KNZ75799.1 - 3.5e-18 65.5 0.0 5.6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KNZ75799.1 - 6.6e-15 55.0 0.0 1.1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KNZ75799.1 - 1.6e-12 47.2 0.0 2.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KNZ75799.1 - 2.1e-10 40.4 0.0 3.6e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KNZ75799.1 - 1.7e-08 34.2 0.0 2.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KNZ75799.1 - 0.00044 20.6 0.0 0.00066 20.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F-box-like PF12937.2 KNZ75800.1 - 0.0012 18.4 5.9 0.0028 17.3 1.3 3.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KNZ75800.1 - 0.0052 16.4 2.2 0.0052 16.4 1.6 2.8 3 0 0 3 3 3 1 F-box domain PRANC PF09372.5 KNZ75800.1 - 0.042 13.8 0.3 0.59 10.1 0.1 2.4 2 0 0 2 2 2 0 PRANC domain ECH PF00378.15 KNZ75801.1 - 5.7e-28 97.6 0.4 9.3e-28 96.9 0.3 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KNZ75801.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region HMG_box PF00505.14 KNZ75803.1 - 0.0059 16.8 2.6 0.0059 16.8 1.8 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box YABBY PF04690.8 KNZ75803.1 - 0.0081 16.4 1.7 0.0081 16.4 1.2 1.5 2 0 0 2 2 2 1 YABBY protein Tannase PF07519.6 KNZ75807.1 - 6e-96 322.0 0.0 8.2e-96 321.5 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KNZ75807.1 - 1.7e-05 24.7 0.0 8.3e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ75807.1 - 4.6e-05 23.1 0.0 0.34 10.6 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ75807.1 - 9.7e-05 22.0 0.0 0.00028 20.5 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold ThiF PF00899.16 KNZ75809.1 - 3.7e-31 107.7 0.0 6.1e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KNZ75809.1 - 0.019 15.0 0.0 0.056 13.5 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Terpene_synth_C PF03936.11 KNZ75810.1 - 5.7e-14 51.9 0.0 7e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain MIS13 PF08202.6 KNZ75812.1 - 1.7e-22 79.8 5.2 4.1e-21 75.3 3.6 2.3 1 1 0 1 1 1 1 Mis12-Mtw1 protein family DUF4288 PF14119.1 KNZ75812.1 - 1.2 9.3 4.4 33 4.6 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) Polysacc_deac_1 PF01522.16 KNZ75814.1 - 1.7e-24 85.8 0.2 3.8e-24 84.6 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF1752 PF08550.5 KNZ75815.1 - 2.3e-12 46.2 0.3 4.6e-12 45.2 0.2 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3295 PF11702.3 KNZ75815.1 - 3.4e-11 42.8 1.4 3.4e-11 42.8 1.0 3.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3295) Fungal_trans PF04082.13 KNZ75816.1 - 1.8e-29 102.3 0.0 3.7e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ75816.1 - 0.0025 17.6 9.1 0.0052 16.6 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TetR PF13972.1 KNZ75816.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial transcriptional repressor Polysacc_deac_1 PF01522.16 KNZ75817.1 - 5.1e-22 77.8 0.1 1e-21 76.8 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide deacetylase zf-DHHC PF01529.15 KNZ75818.1 - 2.8e-33 114.7 6.8 5.9e-33 113.7 4.7 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase FYVE PF01363.16 KNZ75818.1 - 0.074 12.9 6.9 0.15 11.9 4.8 1.5 1 0 0 1 1 1 0 FYVE zinc finger OrfB_Zn_ribbon PF07282.6 KNZ75818.1 - 0.61 9.7 5.7 1.3 8.7 3.9 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Polysacc_deac_1 PF01522.16 KNZ75819.1 - 4.2e-14 52.2 0.0 6e-13 48.5 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide deacetylase ADH_zinc_N PF00107.21 KNZ75820.1 - 6.3e-17 61.3 0.0 1e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ75820.1 - 1.3e-12 47.4 0.0 2.3e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAC PF01849.13 KNZ75820.1 - 0.022 14.3 0.1 0.04 13.4 0.1 1.4 1 0 0 1 1 1 0 NAC domain NmrA PF05368.8 KNZ75820.1 - 0.043 13.0 0.1 0.13 11.4 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family AlaDh_PNT_C PF01262.16 KNZ75820.1 - 0.048 13.2 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MAF_flag10 PF01973.13 KNZ75820.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF115 TetM_leader PF08076.6 KNZ75820.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide GST_N_3 PF13417.1 KNZ75821.1 - 3.2e-20 72.1 0.0 5.6e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KNZ75821.1 - 3.1e-17 62.4 0.0 6e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KNZ75821.1 - 3.6e-12 46.1 0.0 7.8e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KNZ75821.1 - 3.7e-11 42.8 0.0 5.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KNZ75821.1 - 3.8e-07 29.9 0.0 6.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KNZ75822.1 - 3.9e-18 65.4 0.0 7.5e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KNZ75822.1 - 6.2e-14 51.9 0.0 1.7e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KNZ75822.1 - 2.7e-12 46.4 0.0 5.2e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KNZ75822.1 - 4.4e-11 42.6 0.0 6.3e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KNZ75822.1 - 3.3e-07 30.0 0.1 5.4e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_31 PF01055.21 KNZ75822.1 - 0.053 12.3 0.0 0.1 11.4 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolases family 31 SRP54 PF00448.17 KNZ75822.1 - 0.13 11.7 0.0 0.33 10.3 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain WD40 PF00400.27 KNZ75824.1 - 3.7e-186 597.2 54.4 6.9e-14 51.1 0.1 14.7 14 0 0 14 14 14 14 WD domain, G-beta repeat PD40 PF07676.7 KNZ75824.1 - 3.6e-18 64.8 25.2 0.041 13.5 0.2 13.3 13 0 0 13 13 13 7 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 KNZ75824.1 - 1.1e-10 40.4 13.8 0.18 10.0 0.1 6.3 2 1 2 6 6 6 6 Cytochrome D1 heme domain HARP PF07443.8 KNZ75824.1 - 0.00021 20.6 0.5 91 2.5 0.0 7.1 7 0 0 7 7 7 0 HepA-related protein (HARP) NACHT PF05729.7 KNZ75824.1 - 0.00032 20.3 0.0 0.00062 19.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AcetylCoA_hyd_C PF13336.1 KNZ75824.1 - 0.11 12.1 5.5 18 4.9 0.0 5.9 6 2 2 8 8 8 0 Acetyl-CoA hydrolase/transferase C-terminal domain Mg_trans_NIPA PF05653.9 KNZ75824.1 - 0.2 10.6 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium transporter NIPA Proteasome_A_N PF10584.4 KNZ75824.1 - 1.9 7.8 22.7 1.4e+02 1.8 0.0 10.3 13 0 0 13 13 13 0 Proteasome subunit A N-terminal signature IncA PF04156.9 KNZ75825.1 - 0.0062 16.1 0.0 0.028 14.0 0.0 1.8 1 1 0 1 1 1 1 IncA protein DUF4600 PF15372.1 KNZ75825.1 - 0.022 14.9 7.4 0.06 13.5 5.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) UTP15_C PF09384.5 KNZ75825.1 - 0.053 13.2 0.8 5.6 6.6 0.0 2.2 1 1 1 2 2 2 0 UTP15 C terminal HTH_40 PF14493.1 KNZ75825.1 - 0.13 12.4 2.6 0.47 10.7 1.8 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain TSC22 PF01166.13 KNZ75825.1 - 0.24 11.4 2.3 0.38 10.7 0.3 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family Med4 PF10018.4 KNZ75825.1 - 4 6.7 7.9 6.1 6.1 1.2 2.4 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Methyltransf_2 PF00891.13 KNZ75826.1 - 2.1e-29 102.4 0.0 8.8e-29 100.3 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KNZ75826.1 - 0.009 16.5 0.0 0.021 15.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ75826.1 - 0.015 15.7 0.0 0.15 12.5 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 KNZ75826.1 - 0.055 12.7 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain WD40 PF00400.27 KNZ75829.1 - 3.8e-208 666.9 66.1 4.1e-14 51.8 0.0 16.2 16 0 0 16 16 16 16 WD domain, G-beta repeat eIF2A PF08662.6 KNZ75829.1 - 2.2e-21 76.4 0.4 5.3e-05 23.0 0.0 6.4 1 1 9 10 10 10 10 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KNZ75829.1 - 6.9e-19 67.1 28.1 1.7 8.4 0.0 13.4 13 0 0 13 13 13 5 WD40-like Beta Propeller Repeat HARP PF07443.8 KNZ75829.1 - 1.5e-13 49.8 0.0 1.2 8.5 0.0 10.2 11 0 0 11 11 11 1 HepA-related protein (HARP) DUF1258 PF06869.7 KNZ75829.1 - 1.1e-07 31.1 2.2 11 5.0 0.0 8.7 1 1 6 10 10 10 2 Protein of unknown function (DUF1258) Cytochrom_D1 PF02239.11 KNZ75829.1 - 2.6e-07 29.3 15.3 0.018 13.3 0.2 6.0 1 1 5 8 8 8 6 Cytochrome D1 heme domain Thioredox_DsbH PF03190.10 KNZ75829.1 - 2.6e-05 24.0 0.1 44 3.7 0.0 7.3 4 3 7 11 11 11 0 Protein of unknown function, DUF255 PQQ_3 PF13570.1 KNZ75829.1 - 0.0026 17.9 23.5 90 3.5 0.0 11.5 13 1 1 14 14 14 0 PQQ-like domain DUF2173 PF09941.4 KNZ75829.1 - 0.0045 16.8 0.3 44 4.0 0.0 6.0 7 3 0 7 7 7 0 Uncharacterized conserved protein (DUF2173) PLD_C PF12357.3 KNZ75829.1 - 0.0052 16.2 7.6 29 4.2 0.1 9.0 12 2 1 13 13 12 0 Phospholipase D C terminal AcetylCoA_hyd_C PF13336.1 KNZ75829.1 - 0.0062 16.2 4.1 56 3.3 0.0 6.2 3 2 1 6 6 6 0 Acetyl-CoA hydrolase/transferase C-terminal domain DUF3312 PF11768.3 KNZ75829.1 - 0.01 14.1 0.0 36 2.4 0.0 5.1 5 3 4 9 9 9 0 Protein of unknown function (DUF3312) CPSF_A PF03178.10 KNZ75829.1 - 0.035 13.1 0.5 1.2e+02 1.6 0.0 5.8 3 3 2 7 7 7 0 CPSF A subunit region UxaC PF02614.9 KNZ75830.1 - 0.021 13.4 1.7 0.031 12.9 1.2 1.2 1 0 0 1 1 1 0 Glucuronate isomerase OmpH PF03938.9 KNZ75830.1 - 0.16 11.8 2.3 0.23 11.3 1.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4600 PF15372.1 KNZ75830.1 - 0.24 11.6 6.3 0.7 10.1 4.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) RNase_HII PF01351.13 KNZ75830.1 - 1.1 8.8 3.6 1.1 8.8 1.4 1.7 2 0 0 2 2 2 0 Ribonuclease HII Methyltransf_2 PF00891.13 KNZ75831.1 - 1.2e-30 106.4 0.0 2.2e-30 105.6 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 KNZ75831.1 - 0.01 16.3 0.0 0.045 14.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ75831.1 - 0.018 15.6 0.0 0.037 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ75831.1 - 0.03 14.6 0.0 0.13 12.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Abhydrolase_5 PF12695.2 KNZ75833.1 - 7.4e-19 67.9 0.0 1.5e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ75833.1 - 6.7e-15 55.5 0.0 6.3e-14 52.4 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ75833.1 - 1.8e-07 30.9 0.0 2e-06 27.5 0.0 2.5 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KNZ75833.1 - 0.00016 21.1 0.0 0.001 18.5 0.1 2.0 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase BAAT_C PF08840.6 KNZ75833.1 - 0.00048 19.8 0.0 0.0015 18.3 0.0 1.8 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 KNZ75833.1 - 0.006 15.8 0.0 0.018 14.2 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KNZ75833.1 - 0.025 13.8 0.0 0.06 12.6 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.15 KNZ75833.1 - 0.06 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative esterase DUF818 PF05677.7 KNZ75833.1 - 0.085 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Thioesterase PF00975.15 KNZ75833.1 - 0.088 13.0 0.6 6.9 6.8 0.0 2.7 3 0 0 3 3 3 0 Thioesterase domain FSH1 PF03959.8 KNZ75833.1 - 0.091 12.1 0.3 0.31 10.4 0.0 2.0 2 1 1 3 3 3 0 Serine hydrolase (FSH1) DUF2637 PF10935.3 KNZ75833.1 - 0.18 11.7 0.6 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) LBR_tudor PF09465.5 KNZ75836.1 - 0.014 15.0 0.2 0.032 13.8 0.0 1.7 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain RPT PF13446.1 KNZ75837.1 - 0.16 11.4 0.8 0.47 9.8 0.2 2.0 2 0 0 2 2 2 0 A repeated domain in UCH-protein Dioxygenase_C PF00775.16 KNZ75840.1 - 2.5e-10 39.9 0.1 2.9e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Dioxygenase NmrA PF05368.8 KNZ75842.1 - 3.3e-26 91.9 0.0 5.8e-26 91.1 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KNZ75842.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding DUF4286 PF14114.1 KNZ75842.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) NmrA PF05368.8 KNZ75843.1 - 6.8e-18 64.7 0.0 1.3e-17 63.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NmrA PF05368.8 KNZ75846.1 - 5.1e-26 91.3 0.0 9.2e-26 90.5 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KNZ75846.1 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding PI-PLC-X PF00388.14 KNZ75847.1 - 2.5e-07 30.1 0.0 3.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain His_Phos_2 PF00328.17 KNZ75848.1 - 1.1e-11 44.6 0.0 1.7e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GMC_oxred_N PF00732.14 KNZ75849.1 - 1.8e-61 207.9 0.0 2.2e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ75849.1 - 3.1e-37 128.0 0.0 5.4e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KNZ75849.1 - 0.00035 19.5 0.0 0.028 13.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KNZ75849.1 - 0.0023 16.9 0.0 0.0039 16.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KNZ75849.1 - 0.015 15.3 0.0 0.038 14.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KNZ75849.1 - 0.059 12.2 0.0 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.13 KNZ75849.1 - 0.06 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glyco_transf_90 PF05686.7 KNZ75850.1 - 7.3e-21 74.2 0.0 2.4e-20 72.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 90 DUF1422 PF07226.6 KNZ75850.1 - 0.024 14.3 0.2 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) DUF3866 PF12982.2 KNZ75851.1 - 0.18 10.7 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) Lactonase PF10282.4 KNZ75852.1 - 8.6e-34 117.1 0.0 9.9e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Acetyltransf_7 PF13508.1 KNZ75853.1 - 8.2e-11 41.9 0.1 1.3e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ75853.1 - 3.4e-09 36.6 0.0 5.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KNZ75853.1 - 0.0021 17.9 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KNZ75853.1 - 0.013 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.1 KNZ75853.1 - 0.017 15.2 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNZ75853.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Synaptobrevin PF00957.16 KNZ75854.1 - 9e-35 118.1 3.6 1e-34 117.9 2.5 1.0 1 0 0 1 1 1 1 Synaptobrevin TMEM117 PF15113.1 KNZ75854.1 - 0.0058 15.2 1.0 0.0073 14.9 0.7 1.0 1 0 0 1 1 1 1 TMEM117 protein family DUF515 PF04415.7 KNZ75854.1 - 0.016 13.4 0.2 0.016 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF1191 PF06697.7 KNZ75854.1 - 0.073 11.8 0.2 0.073 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Shisa PF13908.1 KNZ75854.1 - 0.19 11.9 0.1 0.19 11.9 0.0 1.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2976 PF11190.3 KNZ75854.1 - 0.25 10.8 3.6 0.13 11.8 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) EPSP_synthase PF00275.15 KNZ75855.1 - 6.3e-120 400.4 0.2 1.1e-119 399.6 0.1 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KNZ75855.1 - 1.1e-97 326.0 0.0 5.9e-97 323.6 0.0 2.0 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KNZ75855.1 - 3.5e-61 206.7 0.0 5.7e-61 206.0 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KNZ75855.1 - 1.5e-33 115.9 0.0 1.7e-32 112.4 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KNZ75855.1 - 1.1e-25 89.5 0.0 1.5e-24 85.8 0.0 2.7 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KNZ75855.1 - 8.3e-14 51.8 0.0 2.7e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 KNZ75855.1 - 1.3e-08 34.4 0.0 1e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 KNZ75855.1 - 0.00084 20.1 0.3 0.0072 17.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain DegS PF05384.6 KNZ75855.1 - 0.17 11.0 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Sensor protein DegS Pkinase PF00069.20 KNZ75856.1 - 5e-57 193.0 0.0 7.4e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ75856.1 - 1.4e-26 93.1 0.0 2e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ75856.1 - 3.6e-12 45.8 0.0 5.2e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KNZ75856.1 - 0.008 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RGS PF00615.14 KNZ75857.1 - 7.7e-10 38.9 1.8 2e-05 24.6 0.1 2.6 2 1 0 2 2 2 2 Regulator of G protein signaling domain ABC2_membrane_4 PF12730.2 KNZ75857.1 - 0.18 10.9 8.5 0.36 9.9 5.9 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4149 PF13664.1 KNZ75857.1 - 1.7 8.7 7.7 0.87 9.6 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) L51_S25_CI-B8 PF05047.11 KNZ75858.1 - 8.1e-14 51.0 0.0 1.1e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Patched PF02460.13 KNZ75859.1 - 5.8 4.6 11.2 0.031 12.1 0.5 1.9 2 0 0 2 2 2 0 Patched family EF-hand_1 PF00036.27 KNZ75860.1 - 6.3e-32 106.4 6.2 1.8e-10 39.3 0.0 3.1 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 KNZ75860.1 - 8.7e-31 105.3 4.3 2.9e-15 55.6 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 KNZ75860.1 - 2.1e-28 98.2 1.0 2.2e-20 72.5 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KNZ75860.1 - 4.2e-21 73.2 1.6 6.6e-07 28.3 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KNZ75860.1 - 5.8e-21 72.4 0.7 1.4e-09 36.9 0.0 3.4 3 1 0 3 3 3 3 EF-hand domain EF-hand_9 PF14658.1 KNZ75860.1 - 4.5e-09 36.0 0.1 0.0017 18.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KNZ75860.1 - 4.6e-08 32.7 1.1 4.5e-05 23.1 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 KNZ75860.1 - 5e-07 29.2 0.1 0.011 15.3 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 KNZ75860.1 - 3.4e-06 27.0 0.0 0.0001 22.2 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 KNZ75860.1 - 6.9e-06 25.9 0.2 1.9e-05 24.5 0.1 1.8 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 KNZ75860.1 - 0.00035 20.0 1.9 0.00044 19.7 1.3 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Poly_export PF02563.11 KNZ75860.1 - 0.054 13.2 0.1 2.4 7.9 0.0 2.2 1 1 1 2 2 2 0 Polysaccharide biosynthesis/export protein Tenui_NCP PF04876.7 KNZ75860.1 - 0.056 12.9 0.0 0.37 10.3 0.0 1.9 1 1 0 1 1 1 0 Tenuivirus major non-capsid protein TerB PF05099.8 KNZ75860.1 - 0.12 12.0 0.4 10 5.8 0.0 2.0 1 1 1 2 2 2 0 Tellurite resistance protein TerB Glyco_hydro_92 PF07971.7 KNZ75861.1 - 2.7e-119 399.1 0.0 3.4e-119 398.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Acetyltransf_3 PF13302.1 KNZ75863.1 - 2.1e-15 57.1 0.0 5.3e-15 55.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ75863.1 - 0.00082 19.3 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KNZ75863.1 - 0.0013 18.7 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_12 PF01670.11 KNZ75864.1 - 9.8e-27 93.6 2.5 2e-26 92.6 1.7 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 NAD_binding_4 PF07993.7 KNZ75865.1 - 8.2e-32 110.0 0.0 1.3e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KNZ75865.1 - 1.2e-28 99.6 0.0 3e-28 98.3 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KNZ75865.1 - 2.7e-10 40.0 0.0 5e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KNZ75865.1 - 0.0042 17.0 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 KNZ75865.1 - 0.029 14.6 0.0 0.087 13.0 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site KR PF08659.5 KNZ75865.1 - 0.044 13.4 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 KR domain DUF1744 PF08490.7 KNZ75867.1 - 8e-98 327.6 0.0 1.1e-97 327.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KNZ75867.1 - 9.1e-63 212.0 0.2 1.6e-62 211.2 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KNZ75867.1 - 2.8e-19 69.2 0.0 8.1e-19 67.7 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KNZ75867.1 - 7.1e-08 32.2 0.1 2e-07 30.7 0.1 1.7 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KNZ75867.1 - 6.4e-05 22.8 0.0 0.00036 20.3 0.0 2.3 1 0 0 1 1 1 1 RNase_H superfamily zf-C4pol PF14260.1 KNZ75867.1 - 0.033 14.1 1.5 0.12 12.4 1.0 1.9 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta NOB1_Zn_bind PF08772.6 KNZ75867.1 - 9.5 6.1 8.0 8 6.3 0.4 2.9 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like MAP65_ASE1 PF03999.7 KNZ75868.1 - 3.8e-60 204.1 1.2 6.8e-57 193.4 0.6 2.2 2 0 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) MFS_1 PF07690.11 KNZ75869.1 - 1.8e-16 59.8 46.5 9.5e-11 40.9 15.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyl-CoA_dh_M PF02770.14 KNZ75870.1 - 1.8e-06 27.3 0.1 6.8e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KNZ75870.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Dimerisation PF08100.6 KNZ75870.1 - 0.09 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain Hydantoinase_B PF02538.9 KNZ75872.1 - 9.6e-185 614.7 0.2 3.6e-184 612.8 0.2 1.7 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase PX PF00787.19 KNZ75873.1 - 7.2e-14 51.5 0.0 6.8e-13 48.3 0.0 2.0 2 0 0 2 2 2 1 PX domain Prenyltrans PF00432.16 KNZ75874.1 - 3.2e-54 180.1 7.0 3.9e-12 45.5 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KNZ75874.1 - 9.4e-29 100.1 0.0 4.4e-14 52.8 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KNZ75874.1 - 4.9e-08 32.9 0.0 0.00011 22.2 0.0 3.1 1 1 2 3 3 3 2 Prenyltransferase-like A2M_comp PF07678.9 KNZ75874.1 - 0.18 10.9 0.0 0.6 9.3 0.0 1.8 3 0 0 3 3 3 0 A-macroglobulin complement component Acetyltransf_1 PF00583.19 KNZ75875.1 - 4.8e-12 45.7 0.0 9.3e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Mss4 PF04421.8 KNZ75875.1 - 9.9e-09 34.9 0.0 2.4e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 Mss4 protein Acetyltransf_7 PF13508.1 KNZ75875.1 - 2.5e-08 33.9 0.0 6.8e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KNZ75875.1 - 9.1e-07 28.7 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KNZ75875.1 - 4.9e-05 22.9 0.0 9.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KNZ75875.1 - 0.0017 18.2 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNZ75875.1 - 0.0038 17.3 0.0 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 KNZ75875.1 - 0.0056 16.3 0.0 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase Acetyltransf_4 PF13420.1 KNZ75875.1 - 0.015 15.2 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KNZ75875.1 - 0.028 14.2 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Glyco_hydro_88 PF07470.8 KNZ75876.1 - 1.4e-58 198.5 3.2 1.7e-58 198.2 2.2 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.9 KNZ75876.1 - 0.0096 15.3 1.5 1.1 8.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 DUF1680 PF07944.7 KNZ75876.1 - 0.021 13.1 0.2 0.031 12.5 0.1 1.3 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_88 PF07470.8 KNZ75877.1 - 3.7e-63 213.5 0.8 4.6e-63 213.3 0.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_88 PF07470.8 KNZ75878.1 - 2.2e-61 207.7 0.5 2.7e-61 207.5 0.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Tbf5 PF06331.7 KNZ75879.1 - 6.2e-12 45.1 0.5 8e-12 44.7 0.4 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Rib_5-P_isom_A PF06026.9 KNZ75880.1 - 4.6e-56 188.8 0.0 5.9e-56 188.5 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 KNZ75880.1 - 0.02 14.5 0.1 0.14 11.7 0.1 2.1 1 1 0 1 1 1 0 DeoR C terminal sensor domain BCS1_N PF08740.6 KNZ75881.1 - 5.8e-25 88.0 0.5 1.3e-24 86.8 0.4 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KNZ75881.1 - 8e-13 48.7 0.0 1.5e-11 44.5 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNZ75881.1 - 0.03 14.2 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Aconitase PF00330.15 KNZ75883.1 - 3.4e-175 583.0 0.2 7.4e-175 581.8 0.1 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KNZ75883.1 - 2e-44 150.8 0.0 4.4e-44 149.7 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF1435 PF07256.7 KNZ75884.1 - 1.1 9.3 6.8 0.87 9.6 1.3 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1435) PIF1 PF05970.9 KNZ75885.1 - 5.1e-07 28.9 3.9 1.4e-05 24.2 2.7 2.9 1 1 0 1 1 1 1 PIF1-like helicase SGL PF08450.7 KNZ75888.1 - 2e-12 47.0 0.6 6e-12 45.4 0.4 1.7 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KNZ75888.1 - 0.014 15.3 0.3 0.09 12.7 0.0 2.5 2 1 0 2 2 2 0 Arylesterase Chlorovi_GP_rpt PF06598.6 KNZ75888.1 - 0.05 13.4 1.2 0.083 12.7 0.0 2.0 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat Cyt-b5 PF00173.23 KNZ75891.1 - 1.2e-12 47.4 0.0 2.2e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 KNZ75891.1 - 4.8e-06 26.2 8.2 4.8e-06 26.2 5.7 2.3 1 1 0 2 2 2 1 Fatty acid desaturase Stig1 PF04885.8 KNZ75893.1 - 0.05 13.7 0.6 0.05 13.7 0.4 1.9 1 1 1 2 2 2 0 Stigma-specific protein, Stig1 HMG_box PF00505.14 KNZ75895.1 - 0.026 14.7 1.5 0.026 14.7 1.1 2.2 2 0 0 2 2 2 0 HMG (high mobility group) box Glycoprotein_G PF00802.14 KNZ75895.1 - 0.33 10.0 8.6 0.52 9.4 5.9 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Med8 PF10232.4 KNZ75896.1 - 0.00056 19.4 0.1 0.00056 19.4 0.1 2.3 2 1 0 2 2 2 1 Mediator of RNA polymerase II transcription complex subunit 8 QRPTase_C PF01729.14 KNZ75896.1 - 0.14 11.6 0.4 0.57 9.6 0.4 1.8 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain RVP_2 PF08284.6 KNZ75897.1 - 0.0095 15.8 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease PIF1 PF05970.9 KNZ75898.1 - 4.4e-47 160.7 0.8 4.8e-46 157.3 0.5 2.0 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ75898.1 - 0.0049 16.4 0.1 0.12 11.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KNZ75898.1 - 0.035 14.2 0.2 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Y_phosphatase PF00102.22 KNZ75898.1 - 0.042 13.1 0.0 0.33 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein-tyrosine phosphatase AAA_16 PF13191.1 KNZ75898.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 KNZ75898.1 - 0.099 12.8 0.5 1.7 8.8 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KNZ75898.1 - 0.15 12.2 0.1 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KNZ75898.1 - 0.16 11.4 0.1 0.42 10.0 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Helitron_like_N PF14214.1 KNZ75899.1 - 6.9e-11 42.2 0.1 6.9e-11 42.2 0.1 1.2 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus Pkinase PF00069.20 KNZ75900.1 - 1.2e-29 103.3 0.0 1.8e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ75900.1 - 1.9e-25 89.4 0.0 3.4e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KNZ75900.1 - 0.019 14.0 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Helitron_like_N PF14214.1 KNZ75901.1 - 3.6e-13 49.6 0.0 4.6e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Gemini_AL1 PF00799.15 KNZ75901.1 - 0.0072 16.1 0.1 0.0083 15.9 0.1 1.1 1 0 0 1 1 1 1 Geminivirus Rep catalytic domain DUF3296 PF11726.3 KNZ75901.1 - 0.008 15.7 0.0 0.0086 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) FF PF01846.14 KNZ75902.1 - 0.02 14.8 0.1 0.71 9.8 0.0 2.3 2 1 0 2 2 2 0 FF domain PIF1 PF05970.9 KNZ75903.1 - 8.6e-110 367.0 0.0 1e-109 366.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ75903.1 - 0.0005 19.7 0.0 0.00091 18.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KNZ75903.1 - 0.054 13.0 0.2 0.11 11.9 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KNZ75903.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Herpes_Helicase PF02689.9 KNZ75904.1 - 0.0021 15.8 0.0 0.0025 15.6 0.0 1.0 1 0 0 1 1 1 1 Helicase SGL PF08450.7 KNZ75905.1 - 1.7e-26 93.1 0.1 3e-26 92.3 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 KNZ75905.1 - 0.0015 18.5 0.0 0.024 14.6 0.0 2.8 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.15 KNZ75905.1 - 0.021 14.8 0.5 0.14 12.1 0.0 2.7 3 1 0 3 3 3 0 Arylesterase Chlorovi_GP_rpt PF06598.6 KNZ75905.1 - 0.035 13.9 0.1 0.16 11.8 0.0 2.2 1 0 0 1 1 1 0 Chlorovirus glycoprotein repeat FA_desaturase PF00487.19 KNZ75906.1 - 0.034 13.5 4.5 0.036 13.4 2.6 1.4 1 1 0 1 1 1 0 Fatty acid desaturase NfeD PF01957.13 KNZ75906.1 - 0.041 14.0 0.3 0.041 14.0 0.2 2.1 1 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF2463 PF09591.5 KNZ75906.1 - 0.19 11.2 1.8 0.26 10.8 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2463) CopD PF05425.8 KNZ75906.1 - 0.59 10.3 6.2 0.42 10.8 0.9 2.2 1 1 1 2 2 2 0 Copper resistance protein D DUF1664 PF07889.7 KNZ75906.1 - 1.8 8.3 6.1 0.28 10.9 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1469 PF07332.6 KNZ75906.1 - 1.9 8.2 6.1 6 6.6 2.6 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) DUF202 PF02656.10 KNZ75906.1 - 3.5 7.9 6.3 4.9 7.4 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF3317 PF11779.3 KNZ75907.1 - 6.4e-05 22.3 4.8 8.7e-05 21.8 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Peptidase_A8 PF01252.13 KNZ75907.1 - 0.023 14.3 0.2 0.028 14.0 0.1 1.2 1 0 0 1 1 1 0 Signal peptidase (SPase) II DUF3317 PF11779.3 KNZ75908.1 - 9.7e-06 24.9 4.1 0.0029 16.9 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3317) Ycf4 PF02392.11 KNZ75908.1 - 0.13 11.5 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 Ycf4 FAD_binding_8 PF08022.7 KNZ75909.1 - 4.1e-13 49.1 0.0 6.9e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KNZ75909.1 - 2.8e-12 46.8 8.7 5.6e-12 45.8 6.0 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KNZ75909.1 - 2e-10 40.7 0.0 5e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF2069 PF09842.4 KNZ75909.1 - 0.00087 19.2 2.1 0.00087 19.2 1.5 2.7 3 0 0 3 3 3 1 Predicted membrane protein (DUF2069) Pyr_redox_2 PF07992.9 KNZ75910.1 - 4.6e-27 95.2 0.0 8.2e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KNZ75910.1 - 1.4e-11 44.6 0.0 5.8e-10 39.4 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNZ75910.1 - 3.3e-05 24.0 0.0 0.0064 16.5 0.0 3.2 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KNZ75910.1 - 0.013 15.7 0.2 0.22 11.7 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding HI0933_like PF03486.9 KNZ75910.1 - 0.48 8.8 2.8 0.84 8.0 0.0 2.4 2 1 1 3 3 3 0 HI0933-like protein Spc97_Spc98 PF04130.8 KNZ75911.1 - 5.5e-105 351.7 3.2 4.7e-81 272.7 0.0 2.1 2 0 0 2 2 2 2 Spc97 / Spc98 family Peptidase_C2 PF00648.16 KNZ75912.1 - 7.5e-62 209.0 0.5 1.8e-40 138.7 0.0 2.2 1 1 0 2 2 2 2 Calpain family cysteine protease MCC-bdg_PDZ PF10506.4 KNZ75912.1 - 0.041 13.6 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Daxx PF03344.10 KNZ75912.1 - 0.33 9.3 10.3 0.48 8.8 7.2 1.1 1 0 0 1 1 1 0 Daxx Family Dna2 PF08696.6 KNZ75913.1 - 6e-55 185.8 0.2 1.1e-54 184.9 0.2 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 KNZ75913.1 - 1.5e-52 177.9 0.0 2.3e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KNZ75913.1 - 4.8e-40 137.6 0.2 7.6e-20 71.4 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 KNZ75913.1 - 1.3e-13 50.9 0.0 2.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.2 KNZ75913.1 - 3.4e-13 49.5 0.0 6.2e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.1 KNZ75913.1 - 2.6e-08 33.5 0.9 5.4e-08 32.4 0.1 2.0 2 0 0 2 2 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KNZ75913.1 - 1.4e-07 31.3 1.3 0.2 11.1 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 KNZ75913.1 - 1.3e-05 24.9 0.0 3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Helicase Cas_Cas4 PF01930.12 KNZ75913.1 - 0.00032 20.6 1.5 0.0048 16.8 0.6 2.9 2 1 0 2 2 2 1 Domain of unknown function DUF83 AAA_16 PF13191.1 KNZ75913.1 - 0.00062 19.8 0.0 0.0042 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KNZ75913.1 - 0.0025 17.9 0.3 0.17 11.9 0.0 3.4 2 1 0 2 2 2 1 AAA domain PIF1 PF05970.9 KNZ75913.1 - 0.0027 16.7 0.0 0.15 10.9 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase T2SE PF00437.15 KNZ75913.1 - 0.0044 15.9 0.0 0.0082 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KNZ75913.1 - 0.0046 16.4 0.6 0.075 12.4 0.2 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family ResIII PF04851.10 KNZ75913.1 - 0.0067 16.2 0.6 0.039 13.7 0.4 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KNZ75913.1 - 0.0082 15.4 0.2 0.016 14.5 0.1 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain MobB PF03205.9 KNZ75913.1 - 0.0091 15.7 0.3 0.022 14.4 0.2 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KNZ75913.1 - 0.018 14.5 0.2 0.045 13.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.17 KNZ75913.1 - 0.02 14.3 0.8 0.037 13.4 0.5 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ArgK PF03308.11 KNZ75913.1 - 0.027 13.2 0.2 0.064 12.0 0.0 1.6 2 0 0 2 2 2 0 ArgK protein CbiA PF01656.18 KNZ75913.1 - 0.032 13.6 0.1 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.4 KNZ75913.1 - 0.033 13.1 0.0 0.058 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 KNZ75913.1 - 0.041 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KNZ75913.1 - 0.041 14.0 0.0 0.097 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KNZ75913.1 - 0.052 12.9 0.2 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KNZ75913.1 - 0.072 11.7 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 KNZ75913.1 - 0.076 12.9 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 KNZ75913.1 - 0.11 11.6 0.0 0.85 8.7 0.0 2.3 3 0 0 3 3 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 KNZ75913.1 - 0.31 10.5 2.5 0.73 9.3 1.0 2.2 1 1 1 2 2 2 0 AAA domain CUE PF02845.11 KNZ75915.1 - 4e-10 38.9 0.0 6.4e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain Tup_N PF08581.5 KNZ75916.1 - 0.0043 17.2 0.3 0.012 15.8 0.2 1.7 1 0 0 1 1 1 1 Tup N-terminal stn_TNFRSF12A PF12191.3 KNZ75916.1 - 0.016 15.2 0.1 0.039 13.9 0.0 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain EphA2_TM PF14575.1 KNZ75916.1 - 0.024 15.0 0.4 0.066 13.6 0.3 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Tfb4 PF03850.9 KNZ75916.1 - 0.046 12.9 0.6 0.065 12.4 0.0 1.6 2 0 0 2 2 2 0 Transcription factor Tfb4 Alpha_GJ PF03229.8 KNZ75916.1 - 9 6.6 10.1 0.28 11.5 1.1 2.6 2 1 0 2 2 2 0 Alphavirus glycoprotein J SNARE PF05739.14 KNZ75917.1 - 2.4e-10 39.9 1.0 6.1e-10 38.6 0.7 1.7 1 0 0 1 1 1 1 SNARE domain Sec20 PF03908.8 KNZ75917.1 - 0.095 12.4 0.1 5.8 6.6 0.0 2.6 2 1 0 2 2 2 0 Sec20 Apc1 PF12859.2 KNZ75917.1 - 6.7 6.9 8.9 9.4 6.5 2.6 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 1 GATase PF00117.23 KNZ75918.1 - 3.8e-05 23.2 0.0 7.9e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Pol_alpha_B_N PF08418.5 KNZ75919.1 - 0.5 9.8 15.4 0.66 9.4 10.7 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal APH PF01636.18 KNZ75920.1 - 1.4e-08 34.7 0.0 2.5e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ75920.1 - 0.094 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 KNZ75921.1 - 1.8e-05 24.6 0.1 0.00022 21.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ75921.1 - 0.00066 18.8 0.0 0.0015 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain rRNA_processing PF08524.6 KNZ75921.1 - 0.011 15.5 0.5 3.1 7.5 0.1 2.3 2 0 0 2 2 2 0 rRNA processing PIF1 PF05970.9 KNZ75922.1 - 2.1e-53 181.5 0.2 2.3e-53 181.4 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ75922.1 - 0.00099 18.7 0.0 0.0016 18.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KNZ75922.1 - 0.0027 17.2 0.2 0.0094 15.4 0.1 1.8 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KNZ75922.1 - 0.042 14.0 0.1 0.18 11.9 0.1 1.9 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KNZ75922.1 - 0.16 11.3 0.2 0.4 10.0 0.1 1.6 1 1 0 2 2 2 0 AAA domain Helitron_like_N PF14214.1 KNZ75923.1 - 0.031 13.9 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus PDGF PF00341.12 KNZ75924.1 - 0.017 15.2 0.1 0.037 14.1 0.1 1.5 1 0 0 1 1 1 0 PDGF/VEGF domain ASFV_p27 PF06556.6 KNZ75924.1 - 0.054 13.3 0.5 0.12 12.2 0.3 1.6 1 0 0 1 1 1 0 IAP-like protein p27 C-terminus TFIIA PF03153.8 KNZ75927.1 - 0.48 10.2 4.5 0.56 10.0 3.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Vps26 PF03643.10 KNZ75928.1 - 2.4e-42 144.6 0.1 2.2e-34 118.5 0.1 2.1 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 DUF2839 PF10999.3 KNZ75928.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) PCNA_N PF00705.13 KNZ75930.1 - 2.3e-42 143.4 6.3 3.9e-42 142.7 4.4 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KNZ75930.1 - 7e-28 97.1 0.0 1.4e-13 50.8 0.0 2.6 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KNZ75930.1 - 2.6e-05 23.4 0.3 3.8e-05 22.9 0.0 1.4 2 0 0 2 2 2 1 Rad9 YL1 PF05764.8 KNZ75930.1 - 0.0027 17.3 3.8 0.0034 17.0 2.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Hus1 PF04005.7 KNZ75930.1 - 0.073 12.0 0.6 4.7 6.0 0.2 2.6 2 1 1 3 3 3 0 Hus1-like protein NMD3 PF04981.8 KNZ75931.1 - 1e-05 24.8 2.9 0.00032 19.8 0.0 2.2 1 1 1 2 2 2 2 NMD3 family Glyco_hyd_65N_2 PF14498.1 KNZ75932.1 - 1.1e-31 110.3 0.1 1.5e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Paf67 PF10255.4 KNZ75933.1 - 1.2e-141 472.2 0.0 3.6e-141 470.7 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Apc3 PF12895.2 KNZ75933.1 - 0.0068 16.5 0.1 0.066 13.3 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KNZ75933.1 - 0.06 13.2 0.0 0.49 10.3 0.0 2.1 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ75933.1 - 0.081 12.8 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3283 PF11686.3 KNZ75934.1 - 0.16 11.7 0.3 0.16 11.7 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) Glyco_trans_2_3 PF13632.1 KNZ75935.1 - 1e-52 178.6 2.3 1e-52 178.6 1.6 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KNZ75935.1 - 2.2e-11 43.9 0.5 2.4e-10 40.6 0.3 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KNZ75935.1 - 0.00015 21.5 0.1 0.00088 18.9 0.0 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KNZ75935.1 - 0.0025 17.1 0.1 0.0055 15.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 KNZ75936.1 - 1.3e-18 67.0 0.2 2.5e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 vATP-synt_E PF01991.13 KNZ75937.1 - 2.2e-53 180.4 8.7 2.6e-53 180.2 6.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.1 KNZ75937.1 - 0.17 12.0 3.2 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) Ribosomal_S2 PF00318.15 KNZ75937.1 - 0.9 8.7 4.4 1.7 7.8 3.0 1.6 1 1 0 1 1 1 0 Ribosomal protein S2 Kinesin PF00225.18 KNZ75938.1 - 1.8e-91 306.3 0.0 2.1e-50 171.3 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Mit_KHE1 PF10173.4 KNZ75938.1 - 0.059 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related HR1 PF02185.11 KNZ75938.1 - 0.21 11.3 8.1 0.094 12.4 0.2 3.5 3 1 1 4 4 4 0 Hr1 repeat Pox_A_type_inc PF04508.7 KNZ75938.1 - 0.91 9.4 8.3 0.53 10.2 3.0 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Ribosomal_L14 PF00238.14 KNZ75939.1 - 3.5e-22 78.4 0.0 3.7e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RVP_2 PF08284.6 KNZ75941.1 - 0.031 14.2 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease CMAS PF02353.15 KNZ75947.1 - 2e-64 217.2 0.1 2.5e-64 216.9 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KNZ75947.1 - 1.6e-11 44.1 0.0 2e-10 40.6 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ75947.1 - 1e-10 41.9 0.0 5.1e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ75947.1 - 5.9e-07 29.8 0.0 1.5e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ75947.1 - 1.1e-06 29.1 0.0 3.8e-06 27.4 0.0 1.9 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ75947.1 - 1.9e-06 27.9 0.0 8.4e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KNZ75947.1 - 1.9e-05 24.0 0.0 5.2e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.1 KNZ75947.1 - 0.00022 21.5 0.0 0.00049 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ75947.1 - 0.00056 19.3 0.0 0.00096 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KNZ75947.1 - 0.0014 18.2 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF788 PF05620.6 KNZ75947.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) PCMT PF01135.14 KNZ75947.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 KNZ75947.1 - 0.056 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Metallophos_2 PF12850.2 KNZ75948.1 - 7.5e-19 68.0 0.2 1.2e-18 67.4 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CMAS PF02353.15 KNZ75948.1 - 5.9e-12 45.2 0.0 9.1e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Metallophos PF00149.23 KNZ75948.1 - 0.0002 20.8 2.4 0.29 10.5 0.4 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase MTS PF05175.9 KNZ75948.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 KNZ75948.1 - 0.0029 16.9 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_23 PF13489.1 KNZ75948.1 - 0.021 14.5 0.1 0.061 13.0 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ75948.1 - 0.036 14.6 0.3 0.19 12.3 0.1 2.2 2 1 0 2 2 2 0 Methyltransferase domain PCMT PF01135.14 KNZ75948.1 - 0.061 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) S4 PF01479.20 KNZ75949.1 - 1e-06 28.0 0.1 2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 KNZ75949.1 - 0.00085 18.8 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain PFK PF00365.15 KNZ75950.1 - 2.3e-162 538.6 1.7 8.1e-116 385.9 1.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.14 KNZ75950.1 - 0.048 13.1 0.1 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif SPT6_acidic PF14632.1 KNZ75951.1 - 0.79 9.9 6.6 0.27 11.4 0.4 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 BAALC_N PF06989.7 KNZ75951.1 - 1.2 9.4 4.6 0.38 11.1 0.2 2.1 2 0 0 2 2 2 0 BAALC N-terminus CMAS PF02353.15 KNZ75952.1 - 2.7e-58 197.2 0.0 3.6e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KNZ75952.1 - 1.6e-05 25.4 0.0 3.7e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ75952.1 - 0.00021 21.7 0.0 0.00044 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ75952.1 - 0.00046 19.9 0.0 0.00088 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ75952.1 - 0.0041 16.5 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KNZ75952.1 - 0.019 15.0 0.1 0.051 13.6 0.0 1.7 1 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ75952.1 - 0.03 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SAC3 PF12209.3 KNZ75952.1 - 0.037 14.1 0.2 0.09 12.9 0.0 1.7 2 0 0 2 2 2 0 Leucine permease transcriptional regulator helical domain DOT1 PF08123.8 KNZ75952.1 - 0.084 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 KNZ75952.1 - 0.15 12.5 0.0 0.42 11.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_6 PF12697.2 KNZ75953.1 - 1.9e-12 47.5 0.2 2.5e-12 47.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ75953.1 - 0.00019 21.2 0.1 0.00028 20.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KNZ75953.1 - 0.054 13.0 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) p450 PF00067.17 KNZ75954.1 - 9.7e-64 215.5 0.0 1.1e-63 215.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NMO PF03060.10 KNZ75955.1 - 2.7e-47 161.5 4.2 1.2e-22 80.5 0.6 3.1 3 0 0 3 3 3 3 Nitronate monooxygenase Lipase_GDSL PF00657.17 KNZ75956.1 - 2.1e-08 34.2 0.0 2.4e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase p450 PF00067.17 KNZ75957.1 - 3.7e-13 48.8 0.0 5.2e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PCI PF01399.22 KNZ75958.1 - 1.3e-10 41.5 0.2 1.6e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 PCI domain Ribosomal_S8 PF00410.14 KNZ75959.1 - 4.5e-15 55.6 0.0 8e-15 54.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 VHS PF00790.14 KNZ75960.1 - 2e-36 124.7 0.0 8.7e-36 122.6 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KNZ75960.1 - 6.3e-18 64.6 0.0 1.9e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 GAT domain DUF382 PF04037.8 KNZ75961.1 - 1.1e-56 190.1 0.4 1.1e-56 190.1 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 KNZ75961.1 - 6.3e-19 67.1 5.8 1.2e-18 66.2 4.0 1.5 1 0 0 1 1 1 1 PSP DUF2890 PF11081.3 KNZ75961.1 - 9.3 6.2 12.6 22 5.0 5.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) DBR1 PF05011.8 KNZ75962.1 - 3.2e-31 108.1 0.0 1.3e-30 106.1 0.0 1.9 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KNZ75962.1 - 5.6e-10 38.9 5.4 1.1e-09 37.9 3.8 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KNZ75962.1 - 0.00017 21.4 0.1 0.00037 20.3 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 KNZ75962.1 - 0.016 14.3 0.0 0.039 13.1 0.0 1.6 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily WH1 PF00568.18 KNZ75963.1 - 4.1e-24 84.4 0.0 5.5e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 KNZ75963.1 - 9.2e-05 22.7 0.9 0.00037 20.8 0.0 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain TSP_C PF05735.7 KNZ75963.1 - 0.065 12.7 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 Thrombospondin C-terminal region DUF3020 PF11223.3 KNZ75963.1 - 0.61 10.5 13.6 0.44 10.9 5.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3020) DNA_pol_B PF00136.16 KNZ75964.1 - 9.4e-112 374.1 0.0 2e-111 373.0 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KNZ75964.1 - 1.9e-54 183.9 0.2 3.8e-54 182.8 0.2 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KNZ75964.1 - 2.1e-23 82.6 0.0 3.4e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KNZ75964.1 - 2.1e-15 56.2 5.4 6.2e-15 54.7 3.7 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal PDH PF02153.12 KNZ75965.1 - 1.1e-11 44.1 0.0 1.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 KNZ75965.1 - 8e-06 25.7 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KNZ75965.1 - 9e-05 22.8 0.0 0.00023 21.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KNZ75965.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KNZ75965.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.14 KNZ75965.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KNZ75965.1 - 0.18 11.2 0.3 0.4 10.1 0.2 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ETF_QO PF05187.8 KNZ75966.1 - 3.3e-24 84.9 0.4 3.7e-15 55.8 0.0 3.3 2 1 0 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase NAD_binding_8 PF13450.1 KNZ75966.1 - 2.5e-07 30.6 0.0 7.6e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KNZ75966.1 - 8.2e-07 28.2 0.1 0.00012 21.1 0.6 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ75966.1 - 2.8e-05 23.1 0.7 0.00026 19.9 0.9 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KNZ75966.1 - 3.9e-05 23.6 0.0 9.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNZ75966.1 - 0.00014 21.7 0.6 0.00032 20.4 0.4 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KNZ75966.1 - 0.00017 20.8 0.1 0.00026 20.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KNZ75966.1 - 0.00043 18.8 0.5 0.00076 18.0 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KNZ75966.1 - 0.00045 19.3 0.0 0.0035 16.4 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 KNZ75966.1 - 0.00048 20.2 0.0 0.00088 19.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KNZ75966.1 - 0.0019 17.3 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KNZ75966.1 - 0.0024 16.8 0.3 0.0041 16.0 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KNZ75966.1 - 0.073 11.6 0.2 0.12 10.9 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 KNZ75966.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A RVP_2 PF08284.6 KNZ75968.1 - 0.014 15.3 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Microtub_assoc PF07989.6 KNZ75969.1 - 3.4e-20 71.6 9.3 3.4e-20 71.6 6.5 8.0 10 1 0 10 10 10 2 Microtubule associated Reo_sigmaC PF04582.7 KNZ75969.1 - 0.0035 16.5 3.3 0.0035 16.5 2.3 6.3 3 2 2 7 7 7 3 Reovirus sigma C capsid protein TFIIB PF00382.14 KNZ75971.1 - 2.7e-34 116.7 0.3 3.7e-18 65.1 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KNZ75971.1 - 5.6e-24 84.1 3.5 5.6e-24 84.1 2.4 2.3 2 0 0 2 2 2 1 Brf1-like TBP-binding domain rve PF00665.21 KNZ75971.1 - 2.4e-09 37.3 0.1 5.5e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain TF_Zn_Ribbon PF08271.7 KNZ75971.1 - 1.1e-06 27.8 2.5 2.4e-06 26.7 1.7 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 KNZ75971.1 - 1.2e-06 28.1 0.1 0.023 14.2 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain RRN7 PF11781.3 KNZ75971.1 - 0.0023 17.4 2.9 0.0049 16.3 2.0 1.5 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 A2L_zn_ribbon PF08792.5 KNZ75971.1 - 0.05 13.0 2.2 0.099 12.1 1.5 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain polyprenyl_synt PF00348.12 KNZ75972.1 - 3.7e-47 160.3 0.0 1.5e-43 148.5 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase UBN2_2 PF14227.1 KNZ75973.1 - 3.8e-05 23.2 0.0 5.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ75973.1 - 0.021 14.6 0.2 0.046 13.5 0.1 1.6 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF3829 PF12889.2 KNZ75973.1 - 0.16 11.1 0.3 0.3 10.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Pex19 PF04614.7 KNZ75974.1 - 4.4e-53 180.4 6.8 6.3e-53 179.9 4.7 1.1 1 0 0 1 1 1 1 Pex19 protein family AAA_32 PF13654.1 KNZ75974.1 - 0.01 14.5 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain FliE PF02049.13 KNZ75974.1 - 0.014 15.3 1.3 0.036 14.0 0.5 2.0 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE TCTP PF00838.12 KNZ75974.1 - 0.095 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Translationally controlled tumour protein SNARE PF05739.14 KNZ75975.1 - 1.2e-07 31.3 2.0 1.7e-07 30.8 1.4 1.2 1 0 0 1 1 1 1 SNARE domain FlaC_arch PF05377.6 KNZ75975.1 - 0.032 14.1 0.3 0.052 13.4 0.2 1.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) LPP PF04728.8 KNZ75975.1 - 0.043 13.6 0.1 0.078 12.7 0.1 1.4 1 1 0 1 1 1 0 Lipoprotein leucine-zipper DUF3375 PF11855.3 KNZ75975.1 - 0.068 11.9 0.2 0.075 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) LOH1CR12 PF10158.4 KNZ75975.1 - 0.072 12.8 0.1 0.079 12.7 0.0 1.1 1 0 0 1 1 1 0 Tumour suppressor protein EMP24_GP25L PF01105.19 KNZ75975.1 - 0.12 12.0 0.6 0.13 11.9 0.4 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD polyprenyl_synt PF00348.12 KNZ75976.1 - 1e-22 80.2 0.0 2.5e-18 65.8 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase BING4CT PF08149.6 KNZ75977.1 - 3e-33 113.1 0.0 1.4e-32 111.0 0.0 2.1 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 KNZ75977.1 - 9.1e-11 41.2 0.0 5.1e-09 35.6 0.0 3.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KNZ75977.1 - 0.019 13.2 0.1 0.12 10.6 0.0 2.1 2 1 0 2 2 2 0 Cytochrome D1 heme domain TFIIIC_delta PF12657.2 KNZ75977.1 - 0.025 14.3 0.0 0.082 12.6 0.0 1.8 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Nup160 PF11715.3 KNZ75977.1 - 0.11 10.5 0.1 0.16 10.0 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF1202 PF06717.6 KNZ75977.1 - 0.13 11.4 5.8 0.25 10.5 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) hemP PF10636.4 KNZ75977.1 - 0.42 10.2 3.3 0.19 11.3 0.4 1.9 2 0 0 2 2 2 0 Hemin uptake protein hemP Exo_endo_phos_2 PF14529.1 KNZ75979.1 - 0.1 12.2 0.3 0.2 11.3 0.1 1.6 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase RVT_1 PF00078.22 KNZ75980.1 - 0.0041 16.4 0.0 0.0052 16.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 KNZ75981.1 - 4.4e-09 36.7 0.0 8.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KNZ75981.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like DUF1443 PF07280.6 KNZ75983.1 - 3.2 7.3 0.0 3.2 7.3 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1443) CorA PF01544.13 KNZ75984.1 - 3.4e-13 49.2 0.7 7.2e-12 44.9 0.2 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Pre-SET PF05033.11 KNZ75986.1 - 1.7e-18 66.7 1.2 4.3e-18 65.4 0.8 1.7 1 0 0 1 1 1 1 Pre-SET motif SET PF00856.23 KNZ75986.1 - 1.9e-18 67.3 0.4 4.6e-17 62.7 0.3 2.7 1 1 0 1 1 1 1 SET domain UQ_con PF00179.21 KNZ75987.1 - 4e-39 133.2 0.0 5.5e-39 132.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KNZ75987.1 - 0.005 16.6 0.0 0.0076 15.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KNZ75987.1 - 0.05 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain Glyco_hydro_35 PF01301.14 KNZ75988.1 - 1e-77 261.6 0.3 1.5e-77 261.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 KNZ75988.1 - 2.4e-38 130.7 3.2 2.9e-19 69.3 0.0 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 KNZ75988.1 - 4.7e-23 81.4 4.9 1.2e-22 80.1 3.4 1.7 1 1 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 KNZ75988.1 - 8.9e-14 50.6 1.5 8.9e-14 50.6 0.1 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 ORC5_C PF14630.1 KNZ75989.1 - 1e-51 175.9 0.0 1.2e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus YycC PF14174.1 KNZ75989.1 - 0.012 15.3 0.0 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 YycC-like protein CBM_1 PF00734.13 KNZ75990.1 - 1.1e-10 40.9 8.3 1.1e-10 40.9 5.8 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain AXE1 PF05448.7 KNZ75990.1 - 0.024 13.1 0.1 0.11 10.9 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) PhoPQ_related PF10142.4 KNZ75990.1 - 0.16 10.4 0.2 0.83 8.0 0.1 2.0 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein ParA PF10609.4 KNZ75991.1 - 1e-30 105.3 0.3 1.7e-30 104.7 0.2 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KNZ75991.1 - 2.3e-16 59.8 0.0 3.8e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KNZ75991.1 - 6.7e-07 29.3 0.2 2.4e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 KNZ75991.1 - 0.0002 20.5 0.3 0.0043 16.1 0.2 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 KNZ75991.1 - 0.0019 17.3 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 KNZ75991.1 - 0.0047 16.3 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.1 KNZ75991.1 - 0.058 13.0 0.3 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain F-box-like PF12937.2 KNZ75992.1 - 0.0016 18.1 1.1 0.0065 16.1 0.8 2.1 1 1 0 1 1 1 1 F-box-like ACC_epsilon PF13822.1 KNZ75993.1 - 0.037 14.3 1.2 4.6 7.6 0.0 2.7 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit F-box-like PF12937.2 KNZ75994.1 - 5.4e-05 22.8 0.3 0.00023 20.8 0.2 2.2 1 1 0 1 1 1 1 F-box-like p450 PF00067.17 KNZ75995.1 - 5.4e-66 222.9 0.0 8.6e-66 222.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Nrap PF03813.9 KNZ75997.1 - 9.8e-221 735.0 0.0 1.5e-220 734.4 0.0 1.3 1 0 0 1 1 1 1 Nrap protein LysM PF01476.15 KNZ75998.1 - 1.5e-13 50.3 1.4 3.3e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 LysM domain ThiF PF00899.16 KNZ76000.1 - 3.7e-38 130.4 0.0 7.4e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KNZ76000.1 - 6e-28 96.2 0.0 1.1e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KNZ76000.1 - 2.2e-19 68.5 2.3 2.2e-19 68.5 1.6 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 KNZ76000.1 - 2.9e-07 30.4 0.0 6.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 KNZ76000.1 - 0.013 15.7 0.0 0.047 13.9 0.0 2.0 2 1 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 KNZ76000.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KNZ76000.1 - 0.14 10.9 0.1 1.3 7.8 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Herpes_Helicase PF02689.9 KNZ76004.1 - 4.7e-06 24.6 0.0 5e-06 24.5 0.0 1.0 1 0 0 1 1 1 1 Helicase MIF PF01187.13 KNZ76006.1 - 3.1e-14 53.0 0.0 3.8e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Ribosomal_L18_c PF14204.1 KNZ76006.1 - 0.028 14.9 0.3 3 8.4 0.0 2.1 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region TauD PF02668.11 KNZ76007.1 - 2.3e-27 96.3 0.0 2.8e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Rpp20 PF12328.3 KNZ76008.1 - 1.5e-05 24.6 0.1 0.00015 21.4 0.0 2.2 1 1 1 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P eRF1_2 PF03464.10 KNZ76009.1 - 3.3e-46 156.9 0.1 7.9e-46 155.6 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KNZ76009.1 - 5.1e-39 133.0 0.4 1.1e-38 132.0 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KNZ76009.1 - 1e-26 93.0 0.0 2.2e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 zf-CCHC PF00098.18 KNZ76011.1 - 0.02 14.7 0.8 0.039 13.8 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.1 KNZ76012.1 - 0.00028 21.2 0.0 0.00058 20.3 0.0 1.5 2 0 0 2 2 2 1 Aspartyl protease NSP10 PF09401.5 KNZ76012.1 - 0.0073 16.0 0.0 0.015 15.0 0.0 1.6 1 1 0 1 1 1 1 RNA synthesis protein NSP10 Asp_protease PF09668.5 KNZ76012.1 - 0.02 14.4 0.2 0.15 11.6 0.2 1.9 1 1 1 2 2 2 0 Aspartyl protease rve PF00665.21 KNZ76013.1 - 0.0086 16.1 0.0 0.038 14.1 0.0 1.8 1 1 1 2 2 2 1 Integrase core domain DUF1876 PF08962.6 KNZ76014.1 - 0.016 14.9 0.6 0.026 14.3 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1876) CorA PF01544.13 KNZ76015.1 - 2.9e-44 151.2 1.6 4.1e-44 150.7 1.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 KNZ76015.1 - 0.019 14.7 0.7 0.039 13.7 0.2 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3826 PF12875.2 KNZ76015.1 - 0.045 13.4 0.5 1.3 8.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) A_thal_3526 PF09713.5 KNZ76015.1 - 0.11 12.7 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) ACT_4 PF13291.1 KNZ76015.1 - 0.14 12.4 0.1 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 ACT domain Uds1 PF15456.1 KNZ76016.1 - 8.3e-29 100.0 15.8 8.3e-29 100.0 11.0 6.2 4 2 2 6 6 6 1 Up-regulated During Septation BNIP2 PF12496.3 KNZ76016.1 - 0.092 12.9 0.1 0.092 12.9 0.1 3.4 4 1 0 4 4 4 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DegQ PF08181.6 KNZ76016.1 - 4.9 6.9 14.5 15 5.3 1.1 5.2 4 0 0 4 4 4 0 DegQ (SacQ) family DUF2404 PF10296.4 KNZ76017.1 - 4.3e-05 23.5 0.0 0.0016 18.5 0.0 2.4 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) UPF0154 PF03672.8 KNZ76017.1 - 0.00073 19.1 0.3 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) CheY-binding PF09078.6 KNZ76019.1 - 0.056 13.4 0.3 0.36 10.8 0.0 2.3 2 0 0 2 2 2 0 CheY binding ORMDL PF04061.9 KNZ76020.1 - 2.7e-54 182.4 3.3 3.4e-54 182.0 2.3 1.1 1 0 0 1 1 1 1 ORMDL family THF_DHG_CYH_C PF02882.14 KNZ76021.1 - 2.8e-16 59.0 0.1 5.9e-08 31.9 0.0 2.8 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 KNZ76021.1 - 0.00058 19.9 0.1 0.05 13.6 0.0 2.2 1 1 1 2 2 2 2 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 KNZ76021.1 - 0.011 16.0 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain IPP-2 PF04979.9 KNZ76022.1 - 7.9e-13 48.8 3.6 9.5e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) NmrA PF05368.8 KNZ76023.1 - 1.1e-18 67.3 0.0 1.5e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KNZ76023.1 - 0.096 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Hemerythrin PF01814.18 KNZ76025.1 - 3.1e-08 33.8 1.3 3.8e-05 23.8 0.0 2.2 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain AAA PF00004.24 KNZ76026.1 - 1.8e-54 183.4 0.0 1.5e-39 135.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KNZ76026.1 - 1.5e-10 41.2 0.6 0.00034 20.7 0.2 4.5 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.8 KNZ76026.1 - 2.1e-08 33.3 0.2 0.0034 16.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 KNZ76026.1 - 3.7e-08 33.5 0.1 0.0019 18.1 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KNZ76026.1 - 6.4e-08 33.4 0.0 0.0012 19.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KNZ76026.1 - 1.2e-07 31.3 0.4 0.0039 16.9 0.1 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_5 PF07728.9 KNZ76026.1 - 5.1e-07 29.4 0.1 0.0022 17.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KNZ76026.1 - 6.4e-07 29.7 0.1 0.0012 19.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KNZ76026.1 - 1e-06 28.7 0.5 2.9e-05 24.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KNZ76026.1 - 1.2e-06 27.7 1.4 0.03 13.3 0.0 2.8 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KNZ76026.1 - 1.3e-06 28.3 0.0 0.039 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KNZ76026.1 - 1.2e-05 25.2 0.0 0.1 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KNZ76026.1 - 1.4e-05 24.3 0.1 0.01 14.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KNZ76026.1 - 2e-05 24.1 0.3 0.13 11.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 KNZ76026.1 - 3.5e-05 23.3 3.5 2.5 7.4 0.1 4.3 2 2 2 4 4 4 2 AAA domain DUF2075 PF09848.4 KNZ76026.1 - 4.5e-05 22.6 0.1 0.04 12.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 KNZ76026.1 - 5.5e-05 22.3 0.0 0.07 12.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 KNZ76026.1 - 6.3e-05 23.1 0.0 0.2 11.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase CDC48_N PF02359.13 KNZ76026.1 - 8.3e-05 22.4 0.0 0.00028 20.7 0.0 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain Sigma54_activat PF00158.21 KNZ76026.1 - 0.00012 21.6 0.0 0.18 11.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_30 PF13604.1 KNZ76026.1 - 0.00023 20.8 0.0 0.39 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 KNZ76026.1 - 0.00033 20.2 0.0 0.41 10.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 KNZ76026.1 - 0.00071 19.1 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KNZ76026.1 - 0.00076 19.1 0.1 0.66 9.6 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KNZ76026.1 - 0.00092 18.9 1.4 1.8 8.2 0.0 3.5 3 1 0 3 3 3 2 NACHT domain CDC48_2 PF02933.12 KNZ76026.1 - 0.00096 18.7 0.1 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 ABC_tran PF00005.22 KNZ76026.1 - 0.002 18.4 0.3 0.18 12.0 0.1 2.6 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.1 KNZ76026.1 - 0.0037 17.2 0.0 0.48 10.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 KNZ76026.1 - 0.0052 16.0 0.1 1.8 7.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_24 PF13479.1 KNZ76026.1 - 0.007 15.9 0.7 3.3 7.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KNZ76026.1 - 0.011 14.6 0.2 1.3 7.8 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain SKI PF01202.17 KNZ76026.1 - 0.014 15.2 0.3 1.8 8.3 0.0 2.6 2 1 0 2 2 2 0 Shikimate kinase CPT PF07931.7 KNZ76026.1 - 0.047 13.3 0.1 4.6 6.8 0.0 2.6 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.10 KNZ76026.1 - 0.049 13.4 0.0 7.4 6.3 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit KaiC PF06745.8 KNZ76026.1 - 0.052 12.6 2.0 1.7 7.6 0.0 3.0 3 1 0 3 3 3 0 KaiC Parvo_NS1 PF01057.12 KNZ76026.1 - 0.084 11.7 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Zot PF05707.7 KNZ76026.1 - 0.14 11.5 0.2 17 4.8 0.0 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) KTI12 PF08433.5 KNZ76026.1 - 0.15 11.2 0.1 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.13 KNZ76026.1 - 0.15 11.5 0.0 17 4.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.6 KNZ76026.1 - 0.19 11.6 0.0 7.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Torsin DUF3661 PF12400.3 KNZ76027.1 - 4.9e-38 130.1 7.2 7.1e-38 129.6 5.0 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein DUF2009 PF09418.5 KNZ76028.1 - 2e-205 682.9 0.0 2.3e-205 682.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 KNZ76028.1 - 7.6e-07 28.9 5.4 1.4e-06 28.0 3.7 1.5 1 0 0 1 1 1 1 B-box zinc finger IBR PF01485.16 KNZ76028.1 - 0.45 10.4 5.7 1 9.2 3.9 1.5 1 0 0 1 1 1 0 IBR domain PCI PF01399.22 KNZ76029.1 - 8.2e-13 48.5 0.3 1.4e-11 44.6 0.0 2.3 2 0 0 2 2 2 1 PCI domain Pro-kuma_activ PF09286.6 KNZ76030.1 - 1.3e-36 125.7 0.0 2.3e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KNZ76030.1 - 3.4e-06 26.4 0.0 5.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.6 KNZ76031.1 - 9.7e-40 135.9 0.1 1.6e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KNZ76031.1 - 1e-05 24.8 0.7 6.1e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 Subtilase family Hep_59 PF07052.6 KNZ76032.1 - 1.8e-27 95.6 0.5 1.8e-27 95.6 0.3 2.8 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Gti1_Pac2 PF09729.4 KNZ76033.1 - 6.7e-17 61.8 0.4 9.1e-17 61.4 0.3 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family DLIC PF05783.6 KNZ76034.1 - 1.5e-30 106.3 1.0 3.1e-23 82.2 0.0 3.6 3 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) TIP41 PF04176.8 KNZ76035.1 - 1.3e-52 177.7 0.0 1.6e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family TFIID_20kDa PF03847.8 KNZ76036.1 - 6.2e-28 96.8 0.2 1.1e-27 96.1 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 KNZ76036.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PDZ_2 PF13180.1 KNZ76036.1 - 0.035 13.9 0.0 0.089 12.6 0.0 1.8 1 0 0 1 1 1 0 PDZ domain RRS1 PF04939.7 KNZ76037.1 - 1.8e-58 196.6 3.8 1.8e-58 196.6 2.6 1.6 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) DUF445 PF04286.7 KNZ76037.1 - 1.6 8.2 8.4 2.6 7.4 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) SAA PF00277.13 KNZ76037.1 - 8.3 6.8 9.8 0.44 10.9 0.6 2.7 3 0 0 3 3 3 0 Serum amyloid A protein SPRY PF00622.23 KNZ76038.1 - 2.3e-12 47.0 0.1 4.5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 SPRY domain TFIIS_C PF01096.13 KNZ76039.1 - 1.9e-17 62.5 5.8 1.9e-17 62.5 4.0 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KNZ76039.1 - 6.7e-09 35.2 0.6 6.7e-09 35.2 0.4 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 KNZ76039.1 - 0.0074 16.0 11.8 0.15 11.8 0.2 2.6 2 1 0 2 2 2 2 Transposase zinc-ribbon domain DUF2387 PF09526.5 KNZ76039.1 - 0.057 13.3 9.9 1.8 8.5 0.2 3.0 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Zn_ribbon_recom PF13408.1 KNZ76039.1 - 0.17 12.1 0.1 0.17 12.1 0.1 2.6 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain DZR PF12773.2 KNZ76039.1 - 0.52 10.1 11.8 8.7e+02 -0.2 8.4 2.8 1 1 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.4 KNZ76039.1 - 0.58 9.9 9.6 2.4 7.9 0.4 3.9 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 DNA_RNApol_7kD PF03604.8 KNZ76039.1 - 0.6 9.6 8.3 0.25 10.8 0.4 3.4 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.1 KNZ76039.1 - 0.61 9.8 11.7 0.91 9.2 1.4 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KNZ76039.1 - 0.93 9.1 11.4 0.57 9.8 1.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 KNZ76039.1 - 1.7 8.4 15.5 4.3 7.2 0.1 4.0 3 1 1 4 4 4 0 PhnA Zinc-Ribbon Baculo_LEF5_C PF11792.3 KNZ76039.1 - 2.4 7.6 5.3 2.9 7.3 1.8 2.4 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain HypA PF01155.14 KNZ76039.1 - 5 6.8 9.9 4e+02 0.7 6.8 2.7 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 KNZ76039.1 - 9 6.1 10.3 0.75 9.6 0.2 2.8 2 1 0 2 2 2 0 zinc-ribbons RRM_1 PF00076.17 KNZ76040.1 - 2.9e-12 46.0 0.3 1.1e-07 31.3 0.0 4.0 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ76040.1 - 2.6e-06 27.3 0.0 0.017 15.0 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ76040.1 - 0.00029 20.6 0.0 0.29 11.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_3 PF13738.1 KNZ76041.1 - 3.1e-23 82.8 0.0 8.5e-23 81.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KNZ76041.1 - 1.4e-18 66.4 0.0 2.8e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KNZ76041.1 - 1e-11 44.4 0.4 8.1e-09 34.8 0.1 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KNZ76041.1 - 2.9e-09 37.1 0.0 1.2e-07 31.8 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNZ76041.1 - 1.1e-06 28.5 0.7 0.0013 18.4 0.0 4.1 4 1 1 5 5 5 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KNZ76041.1 - 2.4e-06 27.6 0.0 0.00082 19.4 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KNZ76041.1 - 3.3e-05 24.2 0.1 0.13 12.6 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KNZ76041.1 - 0.00024 21.0 0.0 0.042 13.8 0.0 2.9 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_8 PF13450.1 KNZ76041.1 - 0.00092 19.1 0.0 0.0036 17.2 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 KNZ76041.1 - 0.022 13.8 0.0 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KNZ76041.1 - 0.044 12.6 0.0 0.41 9.5 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein NADH_dh_m_C1 PF15088.1 KNZ76041.1 - 0.066 12.7 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NAD_binding_7 PF13241.1 KNZ76041.1 - 0.096 12.9 0.1 1.3 9.3 0.1 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 KNZ76041.1 - 0.13 11.0 0.1 13 4.5 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A DNA_primase_lrg PF04104.9 KNZ76042.1 - 3e-81 272.5 0.0 4e-81 272.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit SMK-1 PF04802.10 KNZ76043.1 - 1.1e-62 210.9 7.4 1.1e-62 210.9 5.2 2.8 2 1 0 2 2 2 1 Component of IIS longevity pathway SMK-1 MAS20 PF02064.10 KNZ76044.1 - 5.1e-15 55.4 2.2 2.6e-14 53.1 1.5 2.1 1 1 0 1 1 1 1 MAS20 protein import receptor SET PF00856.23 KNZ76044.1 - 3.9e-10 40.2 0.4 6.3e-08 33.0 0.0 2.6 3 0 0 3 3 3 2 SET domain SAF PF08666.7 KNZ76044.1 - 0.0078 16.5 0.6 2.9 8.3 0.0 2.8 2 0 0 2 2 2 2 SAF domain Ecl1 PF12855.2 KNZ76044.1 - 0.091 12.0 0.6 0.19 11.0 0.4 1.5 1 0 0 1 1 1 0 Life-span regulatory factor CLPTM1 PF05602.7 KNZ76046.1 - 1.2e-132 442.7 0.0 1.5e-132 442.4 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 KNZ76046.1 - 0.0027 17.2 0.4 0.0027 17.2 0.3 2.6 3 0 0 3 3 3 1 PQ loop repeat 2TM PF13239.1 KNZ76046.1 - 3.6 7.7 11.0 2.9 8.0 2.8 3.2 2 1 1 3 3 3 0 2TM domain DUF4218 PF13960.1 KNZ76047.1 - 0.053 12.9 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) 14-3-3 PF00244.15 KNZ76048.1 - 2.3e-117 390.1 4.1 2.6e-117 389.9 2.9 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 KNZ76048.1 - 0.058 12.9 3.7 1.7 8.1 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) DUF885 PF05960.6 KNZ76048.1 - 0.097 11.8 2.1 0.072 12.2 0.5 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) PGAP1 PF07819.8 KNZ76049.1 - 6.9e-54 182.8 0.0 1e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KNZ76049.1 - 7.7e-09 35.4 0.1 3.2e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ76049.1 - 3.3e-06 27.1 0.2 7.9e-06 25.9 0.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KNZ76049.1 - 0.0087 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 KNZ76049.1 - 0.052 13.1 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF390 PF04094.9 KNZ76049.1 - 0.39 8.7 0.1 0.59 8.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) PLU-1 PF08429.6 KNZ76050.1 - 4.2e-48 163.9 2.2 9.8e-48 162.7 1.5 1.6 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.17 KNZ76050.1 - 2.6e-41 140.4 2.7 4.9e-41 139.5 0.2 2.7 3 0 0 3 3 3 1 JmjC domain, hydroxylase ARID PF01388.16 KNZ76050.1 - 1.6e-18 66.3 0.1 5.8e-18 64.5 0.0 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 KNZ76050.1 - 1.1e-14 53.6 1.6 2.5e-14 52.4 1.1 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 KNZ76050.1 - 4.4e-14 51.8 45.6 1.2e-09 37.6 7.0 4.8 4 0 0 4 4 4 3 PHD-finger zf-C5HC2 PF02928.11 KNZ76050.1 - 5.8e-11 42.2 10.3 5.8e-11 42.2 7.1 2.8 3 0 0 3 3 3 1 C5HC2 zinc finger Prok-RING_1 PF14446.1 KNZ76050.1 - 0.0034 17.0 7.3 0.0034 17.0 5.1 4.6 5 0 0 5 5 5 2 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KNZ76050.1 - 0.91 8.8 21.8 0.65 9.3 1.5 3.8 3 0 0 3 3 3 0 PHD-finger Abhydrolase_2 PF02230.11 KNZ76051.1 - 7.3e-59 198.8 0.0 1.3e-58 198.0 0.0 1.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KNZ76051.1 - 6.1e-13 48.7 0.0 1.3e-12 47.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ76051.1 - 4e-09 36.7 0.0 1.2e-06 28.6 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KNZ76051.1 - 0.0034 16.9 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 KNZ76051.1 - 0.0097 15.3 0.0 0.017 14.5 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 KNZ76051.1 - 0.014 14.9 0.1 0.7 9.4 0.1 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KNZ76051.1 - 0.04 13.5 0.0 0.085 12.4 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Peptidase_S9 PF00326.16 KNZ76051.1 - 0.072 12.2 0.2 11 5.1 0.2 2.8 2 1 1 3 3 3 0 Prolyl oligopeptidase family Esterase PF00756.15 KNZ76051.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Esterase_phd PF10503.4 KNZ76051.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase tRNA_m1G_MT PF01746.16 KNZ76052.1 - 1.8e-37 128.7 0.1 2.7e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Methyltransf_23 PF13489.1 KNZ76053.1 - 8.2e-14 51.6 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ76053.1 - 5.3e-10 39.6 0.0 9.4e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ76053.1 - 9.5e-08 32.4 0.0 1.8e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ76053.1 - 1.4e-07 31.1 0.0 2.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ76053.1 - 0.0015 19.0 0.0 0.0033 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ76053.1 - 0.014 15.7 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KNZ76053.1 - 0.014 14.7 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 KNZ76053.1 - 0.015 14.3 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 KNZ76053.1 - 0.071 13.0 0.0 0.3 11.0 0.0 1.8 1 1 0 2 2 2 0 FtsJ-like methyltransferase zf-C2H2 PF00096.21 KNZ76054.1 - 0.0062 16.8 10.3 0.12 12.7 0.4 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type RNA_pol_Rpb2_6 PF00562.23 KNZ76056.1 - 1.2e-111 373.2 0.0 1.6e-111 372.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KNZ76056.1 - 9.1e-28 96.5 0.0 1.9e-27 95.5 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 KNZ76056.1 - 8e-26 89.5 0.0 1.8e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 KNZ76056.1 - 5.8e-23 80.6 0.0 1.3e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 KNZ76056.1 - 5.5e-21 74.8 0.0 1.1e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KNZ76056.1 - 2.8e-18 65.9 0.0 1.9e-14 53.6 0.0 2.8 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KNZ76056.1 - 0.0017 18.3 0.1 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Prim_Zn_Ribbon PF08273.7 KNZ76056.1 - 0.11 12.5 1.2 18 5.4 0.0 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Nucleoporin2 PF04096.9 KNZ76057.1 - 4.3e-40 136.7 0.0 6.4e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KNZ76057.1 - 3.5e-20 72.3 313.6 3.5e-06 27.2 37.5 8.7 3 2 5 8 8 8 6 Nucleoporin FG repeat region HIG_1_N PF04588.8 KNZ76058.1 - 0.00014 21.4 0.9 0.00034 20.2 0.6 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MbeD_MobD PF04899.7 KNZ76058.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 MbeD/MobD like PAPS_reduct PF01507.14 KNZ76059.1 - 1.1e-40 139.2 0.0 1.4e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Ribonuclease_3 PF00636.21 KNZ76060.1 - 6.4e-11 42.7 0.0 1.5e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KNZ76060.1 - 3.5e-08 33.4 0.0 1.7e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 KNZ76060.1 - 3.2e-07 30.8 0.0 5.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Cyt-b5 PF00173.23 KNZ76061.1 - 2.2e-25 88.2 0.0 2.7e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IncA PF04156.9 KNZ76063.1 - 0.048 13.2 15.3 0.039 13.5 4.2 2.4 2 0 0 2 2 2 0 IncA protein Syntaxin PF00804.20 KNZ76063.1 - 0.061 13.4 14.6 2.3 8.4 0.2 3.5 2 1 1 3 3 3 0 Syntaxin FlxA PF14282.1 KNZ76063.1 - 0.82 9.6 16.2 0.04 13.8 3.7 2.6 2 0 0 2 2 2 0 FlxA-like protein DUF1759 PF03564.10 KNZ76063.1 - 1.4 8.7 5.1 0.9 9.3 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) Herpes_UL6 PF01763.11 KNZ76063.1 - 3 5.9 9.4 0.65 8.1 0.3 2.2 2 0 0 2 2 2 0 Herpesvirus UL6 like APG6 PF04111.7 KNZ76063.1 - 9.7 5.1 21.5 2.3 7.2 8.6 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 RRM_1 PF00076.17 KNZ76064.1 - 5.9e-23 80.2 0.3 2.7e-12 46.1 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ76064.1 - 2.2e-20 72.4 0.0 6.5e-09 35.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ76064.1 - 9e-10 38.2 0.0 0.001 18.8 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KNZ76064.1 - 0.0011 18.6 0.0 0.0031 17.2 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Elong-fact-P_C PF09285.6 KNZ76064.1 - 0.13 11.6 1.0 0.34 10.2 0.7 1.7 1 0 0 1 1 1 0 Elongation factor P, C-terminal Ofd1_CTDD PF10637.4 KNZ76065.1 - 1.9e-82 276.3 0.0 2.6e-78 262.8 0.0 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KNZ76065.1 - 1e-14 54.8 0.1 9.2e-14 51.7 0.0 2.4 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Glyco_transf_4 PF13439.1 KNZ76068.1 - 0.08 12.6 0.1 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Asp_protease_2 PF13650.1 KNZ76069.1 - 6.9e-05 23.2 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.19 KNZ76071.1 - 3.8e-07 29.6 0.0 5.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KNZ76071.1 - 0.025 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Chromo shadow domain Chromo PF00385.19 KNZ76072.1 - 8.2e-17 60.6 0.1 1e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KNZ76072.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Peptidase_M50 PF02163.17 KNZ76074.1 - 0.13 11.1 1.4 0.82 8.5 0.9 2.0 1 1 0 1 1 1 0 Peptidase family M50 Tetraspannin PF00335.15 KNZ76074.1 - 5.7 6.1 9.1 40 3.3 6.3 2.1 1 1 0 1 1 1 0 Tetraspanin family Btz PF09405.5 KNZ76075.1 - 1.2e-09 38.2 1.7 1.2e-09 38.2 1.2 2.1 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Abhydrolase_6 PF12697.2 KNZ76076.1 - 1.3e-33 116.8 0.3 1.9e-33 116.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ76076.1 - 5.3e-24 85.0 0.0 7.9e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ76076.1 - 4.5e-11 42.6 0.0 1.1e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KNZ76076.1 - 8.7e-08 30.9 0.0 1.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family TFIIF_beta PF02270.10 KNZ76077.1 - 2.5e-44 152.1 0.0 1.6e-43 149.5 0.0 1.9 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit WD40 PF00400.27 KNZ76078.1 - 7.4e-14 51.0 6.8 0.009 15.8 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 KNZ76078.1 - 1.9e-06 27.7 0.0 0.018 14.7 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KNZ76078.1 - 0.071 10.9 0.0 0.18 9.5 0.0 1.6 2 0 0 2 2 2 0 IKI3 family DUF3460 PF11943.3 KNZ76078.1 - 0.12 12.4 0.1 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) F-box-like PF12937.2 KNZ76079.1 - 7e-05 22.4 0.7 7e-05 22.4 0.5 2.1 2 0 0 2 2 2 1 F-box-like HMG_box PF00505.14 KNZ76081.1 - 1.3e-10 41.4 5.1 3e-10 40.2 3.5 1.6 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KNZ76081.1 - 4.6e-09 36.5 1.5 8.5e-09 35.6 1.1 1.4 1 0 0 1 1 1 1 HMG-box domain HhH-GPD PF00730.20 KNZ76082.1 - 2.4e-12 47.0 0.0 3.8e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KNZ76082.1 - 0.013 15.1 0.0 0.093 12.4 0.0 2.4 3 0 0 3 3 3 0 Helix-hairpin-helix motif Helitron_like_N PF14214.1 KNZ76083.1 - 5.7e-06 26.1 0.2 2.8e-05 23.9 0.1 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.1 KNZ76084.1 - 5.9e-24 84.7 0.0 7.5e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ76084.1 - 0.0068 15.9 0.0 0.0077 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) Gemini_AL1 PF00799.15 KNZ76084.1 - 0.019 14.8 0.1 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain PIF1 PF05970.9 KNZ76086.1 - 2.4e-103 345.9 0.0 2.8e-103 345.6 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 KNZ76086.1 - 2.9e-07 28.6 0.0 3.8e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ76086.1 - 0.0002 21.4 0.0 0.0004 20.4 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KNZ76086.1 - 0.00076 19.0 0.3 0.13 11.7 0.1 2.5 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KNZ76086.1 - 0.0022 17.6 0.0 0.0044 16.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF521 PF04412.8 KNZ76087.1 - 0.051 12.1 0.0 0.058 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF521) RasGEF_N_2 PF14663.1 KNZ76087.1 - 0.088 12.7 0.4 0.11 12.4 0.3 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Mu-like_Com PF10122.4 KNZ76087.1 - 0.097 11.7 1.2 0.2 10.7 0.8 1.7 1 1 0 1 1 1 0 Mu-like prophage protein Com zf-RVT PF13966.1 KNZ76087.1 - 0.39 11.0 2.4 0.79 10.0 1.4 1.7 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase RNase_H PF00075.19 KNZ76088.1 - 5.3e-07 30.0 0.1 8.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 RNase H G-alpha PF00503.15 KNZ76090.1 - 2.6e-123 411.5 2.4 3.1e-123 411.3 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KNZ76090.1 - 1.5e-14 53.6 0.5 2.8e-12 46.2 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KNZ76090.1 - 0.00019 20.6 3.2 0.00075 18.6 0.0 2.5 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KNZ76090.1 - 0.012 16.1 0.5 0.11 13.0 0.0 2.6 3 1 0 3 3 3 0 Miro-like protein zf-CHC2 PF01807.15 KNZ76090.1 - 0.025 14.0 0.1 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 CHC2 zinc finger DoxX_3 PF13781.1 KNZ76091.1 - 0.09 13.1 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 DoxX-like family PAPA-1 PF04795.7 KNZ76092.1 - 0.00017 22.2 5.7 0.00038 21.1 3.9 1.6 1 0 0 1 1 1 1 PAPA-1-like conserved region HMG_box PF00505.14 KNZ76093.1 - 1.2e-13 51.0 0.1 2.2e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KNZ76093.1 - 0.00014 22.1 0.0 0.00025 21.3 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain CTD PF12815.2 KNZ76095.1 - 0.25 11.7 7.1 1 9.8 1.9 2.2 2 0 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Helitron_like_N PF14214.1 KNZ76096.1 - 1.2e-22 80.4 0.0 1.7e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Gemini_AL1 PF00799.15 KNZ76096.1 - 0.087 12.6 0.5 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain Acetyltransf_7 PF13508.1 KNZ76097.1 - 3.7e-08 33.4 0.0 5.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ76097.1 - 1.7e-05 24.7 0.0 2.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KNZ76097.1 - 0.0019 18.2 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KNZ76097.1 - 0.067 13.0 0.0 0.091 12.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UPF0220 PF05255.6 KNZ76098.1 - 1.3e-50 170.8 0.1 1.7e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3169 PF11368.3 KNZ76098.1 - 0.078 12.1 0.9 0.11 11.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) RabGAP-TBC PF00566.13 KNZ76101.1 - 1.4e-24 86.7 0.5 2.1e-24 86.2 0.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pol_alpha_B_N PF08418.5 KNZ76101.1 - 0.058 12.9 0.1 0.085 12.3 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DBR1 PF05011.8 KNZ76102.1 - 8.9e-29 100.2 0.0 1.7e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KNZ76102.1 - 1.6e-05 24.4 0.8 3.6e-05 23.2 0.5 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 KNZ76102.1 - 0.015 14.4 0.0 0.038 13.1 0.0 1.5 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DDE_Tnp_4 PF13359.1 KNZ76103.1 - 1.8e-14 53.6 0.0 2.6e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 KNZ76103.1 - 0.0018 17.6 0.0 0.0027 17.0 0.0 1.4 1 1 0 1 1 1 1 Plant transposon protein Pyr_redox_3 PF13738.1 KNZ76104.1 - 1e-15 58.3 0.0 4.3e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KNZ76104.1 - 6.9e-10 37.7 0.1 1.9e-08 33.0 0.1 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KNZ76104.1 - 2.9e-06 26.4 0.0 0.0047 15.9 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KNZ76104.1 - 6.2e-05 23.3 0.0 0.0074 16.6 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ76104.1 - 0.00025 20.9 0.0 0.00059 19.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KNZ76104.1 - 0.0044 16.8 0.1 2.5 7.8 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 KNZ76104.1 - 0.022 13.7 0.1 0.077 11.8 0.1 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 KNZ76104.1 - 0.032 13.3 0.0 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 KNZ76104.1 - 0.033 14.0 0.0 0.081 12.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KNZ76104.1 - 0.035 13.2 0.0 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KNZ76104.1 - 0.045 12.8 0.0 0.086 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KNZ76104.1 - 0.051 12.0 0.0 0.073 11.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 KNZ76104.1 - 0.096 11.5 0.0 0.2 10.4 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 KNZ76105.1 - 3e-26 92.7 0.0 7.7e-25 88.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KNZ76105.1 - 1.1e-18 66.8 0.0 6.9e-17 60.8 0.0 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KNZ76105.1 - 3.9e-12 45.7 0.0 2.9e-07 29.7 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KNZ76105.1 - 2.9e-11 43.6 0.0 7.6e-09 35.7 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KNZ76105.1 - 3.3e-09 36.1 0.3 0.00038 19.4 0.0 3.6 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KNZ76105.1 - 1e-07 32.2 0.1 0.0026 18.1 0.0 3.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNZ76105.1 - 3.6e-05 23.5 0.3 0.18 11.5 0.0 3.4 2 1 1 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KNZ76105.1 - 0.00014 21.0 0.0 0.12 11.3 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KNZ76105.1 - 0.00056 19.8 0.0 0.0025 17.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 KNZ76105.1 - 0.0013 17.9 0.0 0.048 12.8 0.0 2.6 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 KNZ76105.1 - 0.0022 16.5 0.0 0.16 10.3 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.7 KNZ76105.1 - 0.0038 16.2 0.0 0.76 8.6 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KNZ76105.1 - 0.0044 15.9 0.3 0.055 12.3 0.0 2.5 2 1 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 KNZ76105.1 - 0.0062 15.6 0.0 2.2 7.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 KNZ76105.1 - 0.014 14.2 0.1 0.41 9.4 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 KNZ76105.1 - 0.02 14.5 0.0 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KNZ76105.1 - 0.057 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Amino_oxidase PF01593.19 KNZ76105.1 - 0.068 12.2 0.0 8.5 5.3 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase PMT PF02366.13 KNZ76106.1 - 0.45 9.8 7.3 1.6 7.9 1.0 2.1 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase p31comet PF06581.7 KNZ76107.1 - 0.089 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding Sin_N PF04801.8 KNZ76107.1 - 0.11 11.2 0.1 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region F-box-like PF12937.2 KNZ76109.1 - 0.00037 20.1 0.1 0.00037 20.1 0.1 2.6 3 0 0 3 3 3 1 F-box-like Cation_efflux PF01545.16 KNZ76110.1 - 2.3e-06 26.8 0.0 4.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Cation efflux family Tfb2 PF03849.9 KNZ76111.1 - 0.016 13.8 0.2 0.019 13.6 0.1 1.0 1 0 0 1 1 1 0 Transcription factor Tfb2 WH1 PF00568.18 KNZ76111.1 - 0.08 12.6 0.2 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 WH1 domain F-box-like PF12937.2 KNZ76112.1 - 3.3e-08 33.1 0.0 1.4e-07 31.1 0.0 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ76112.1 - 0.35 10.5 3.2 2.3 7.9 0.0 3.5 3 0 0 3 3 3 0 F-box domain DUF904 PF06005.7 KNZ76113.1 - 2.1e-06 27.9 10.9 2.1e-06 27.9 7.6 3.1 2 1 2 4 4 3 1 Protein of unknown function (DUF904) IncA PF04156.9 KNZ76113.1 - 7.7e-06 25.6 13.6 2.1e-05 24.1 8.5 2.2 2 0 0 2 2 2 1 IncA protein CCDC155 PF14662.1 KNZ76113.1 - 0.00028 20.5 12.3 0.00052 19.6 8.5 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 bZIP_2 PF07716.10 KNZ76113.1 - 0.00042 20.0 20.9 0.082 12.7 0.3 5.5 4 1 2 6 6 6 2 Basic region leucine zipper bZIP_1 PF00170.16 KNZ76113.1 - 0.00043 20.1 17.4 0.036 14.0 2.0 3.8 2 1 3 5 5 4 3 bZIP transcription factor GAS PF13851.1 KNZ76113.1 - 0.00091 18.4 9.8 0.00091 18.4 6.8 2.1 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 KNZ76113.1 - 0.0012 18.6 6.7 0.0012 18.6 4.7 2.8 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Transposase_22 PF02994.9 KNZ76113.1 - 0.0013 17.2 5.1 0.0019 16.7 3.5 1.2 1 0 0 1 1 1 1 L1 transposable element BLOC1_2 PF10046.4 KNZ76113.1 - 0.0025 17.8 7.1 0.023 14.8 2.4 2.7 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2968 PF11180.3 KNZ76113.1 - 0.0029 17.0 3.6 0.0053 16.1 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) APG6 PF04111.7 KNZ76113.1 - 0.0038 16.3 10.1 0.0038 16.3 7.0 1.7 1 1 0 1 1 1 1 Autophagy protein Apg6 Myosin_tail_1 PF01576.14 KNZ76113.1 - 0.0038 15.0 10.1 0.0038 15.0 7.0 1.9 1 1 1 2 2 2 1 Myosin tail Kinesin-relat_1 PF12711.2 KNZ76113.1 - 0.0059 16.9 14.8 0.023 15.1 6.2 2.9 2 1 1 3 3 2 1 Kinesin motor FlaC_arch PF05377.6 KNZ76113.1 - 0.0063 16.3 12.8 0.096 12.5 3.8 4.3 2 1 0 3 3 3 1 Flagella accessory protein C (FlaC) ADIP PF11559.3 KNZ76113.1 - 0.0093 15.8 5.5 0.0093 15.8 3.8 2.6 2 1 2 4 4 3 2 Afadin- and alpha -actinin-Binding CALCOCO1 PF07888.6 KNZ76113.1 - 0.0096 14.2 11.0 0.013 13.8 7.6 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 KNZ76113.1 - 0.036 13.2 1.1 0.054 12.6 0.8 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein RTBV_P46 PF06216.6 KNZ76113.1 - 0.037 12.8 5.9 0.009 14.9 1.9 1.5 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein Spc7 PF08317.6 KNZ76113.1 - 0.041 12.5 9.2 0.063 11.9 6.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 KNZ76113.1 - 0.058 13.2 19.6 0.023 14.5 10.9 2.2 2 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 KNZ76113.1 - 0.062 12.8 15.5 1.2 8.6 4.1 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3450 PF11932.3 KNZ76113.1 - 0.066 12.4 4.6 0.13 11.4 2.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2340 PF10209.4 KNZ76113.1 - 0.067 13.3 0.5 0.95 9.6 0.1 2.6 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2340) Mod_r PF07200.8 KNZ76113.1 - 0.073 12.9 11.8 0.17 11.7 7.9 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein HDV_ag PF01517.13 KNZ76113.1 - 0.096 12.3 1.3 0.16 11.5 0.9 1.4 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen TMF_TATA_bd PF12325.3 KNZ76113.1 - 0.15 11.8 10.0 0.4 10.4 6.2 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Striatin PF08232.7 KNZ76113.1 - 0.15 12.3 13.8 0.19 12.0 4.5 3.0 2 1 1 3 3 3 0 Striatin family TMCO5 PF14992.1 KNZ76113.1 - 0.16 11.0 13.3 0.27 10.3 9.2 1.4 1 0 0 1 1 1 0 TMCO5 family HALZ PF02183.13 KNZ76113.1 - 0.21 11.3 16.8 2 8.1 0.1 4.1 3 1 1 4 4 3 0 Homeobox associated leucine zipper DivIC PF04977.10 KNZ76113.1 - 0.25 10.8 17.8 2.8 7.4 3.5 3.9 2 1 2 4 4 3 0 Septum formation initiator DUF4140 PF13600.1 KNZ76113.1 - 0.25 11.7 8.3 1.1 9.7 0.6 3.2 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 KNZ76113.1 - 0.31 11.4 15.1 1.5 9.1 8.1 3.3 2 1 1 3 3 2 0 Protein of unknown function (DUF972) TMPIT PF07851.8 KNZ76113.1 - 0.35 9.9 4.2 0.51 9.3 2.9 1.3 1 0 0 1 1 1 0 TMPIT-like protein Tropomyosin_1 PF12718.2 KNZ76113.1 - 0.45 10.3 14.9 1.5 8.6 10.2 2.0 1 1 0 1 1 1 0 Tropomyosin like DMPK_coil PF08826.5 KNZ76113.1 - 0.46 10.4 12.1 1.4 8.8 3.2 2.6 1 1 1 2 2 2 0 DMPK coiled coil domain like DUF4145 PF13643.1 KNZ76113.1 - 0.52 10.2 7.0 21 5.0 4.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4145) DUF724 PF05266.9 KNZ76113.1 - 0.54 9.8 13.1 4.2 6.9 4.3 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF724) Atg14 PF10186.4 KNZ76113.1 - 0.59 9.0 14.9 2.1 7.1 10.3 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PhoU PF01895.14 KNZ76113.1 - 0.59 10.6 7.6 3.1 8.2 0.5 2.9 1 1 1 2 2 2 0 PhoU domain Ax_dynein_light PF10211.4 KNZ76113.1 - 0.66 9.7 10.8 0.25 11.1 1.0 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain Rho_Binding PF08912.6 KNZ76113.1 - 1.5 9.1 11.5 2.5 8.4 1.6 2.7 2 0 0 2 2 2 0 Rho Binding Cep57_MT_bd PF06657.8 KNZ76113.1 - 1.6 8.7 9.7 7.6 6.5 4.8 2.7 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DivIVA PF05103.8 KNZ76113.1 - 1.7 8.7 10.7 6.3 6.8 2.2 2.8 1 1 1 2 2 2 0 DivIVA protein DUF1664 PF07889.7 KNZ76113.1 - 2.6 7.8 6.3 3.3 7.5 3.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CtIP_N PF10482.4 KNZ76113.1 - 2.9 7.6 17.7 0.8 9.5 6.9 2.9 2 1 1 3 3 2 0 Tumour-suppressor protein CtIP N-terminal domain TSC22 PF01166.13 KNZ76113.1 - 3.2 7.7 13.9 0.78 9.7 2.2 3.7 1 1 2 3 3 3 0 TSC-22/dip/bun family DUF342 PF03961.8 KNZ76113.1 - 3.7 5.8 9.7 0.2 10.0 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) CENP-Q PF13094.1 KNZ76113.1 - 4.3 7.3 16.6 22 5.0 11.5 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CASP_C PF08172.7 KNZ76113.1 - 4.6 6.1 12.5 2.1 7.3 3.6 3.0 2 1 2 4 4 4 0 CASP C terminal TMF_DNA_bd PF12329.3 KNZ76113.1 - 5.4 6.9 20.2 0.59 9.9 8.0 3.3 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF2205 PF10224.4 KNZ76113.1 - 7 6.3 11.7 0.7 9.5 3.7 2.5 2 1 0 2 2 1 0 Predicted coiled-coil protein (DUF2205) Cep57_CLD_2 PF14197.1 KNZ76113.1 - 8.7 6.3 20.0 2.6 8.0 8.2 3.7 4 1 0 4 4 2 0 Centrosome localisation domain of PPC89 Transket_pyr PF02779.19 KNZ76114.1 - 1.8e-59 200.2 0.0 2.6e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KNZ76114.1 - 4.4e-25 88.0 0.0 1.3e-24 86.4 0.0 1.6 1 1 0 1 1 1 1 Dehydrogenase E1 component DUF3641 PF12345.3 KNZ76114.1 - 0.091 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3641) RVP_2 PF08284.6 KNZ76115.1 - 0.0019 18.1 0.0 0.0023 17.8 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_C5 PF00770.13 KNZ76115.1 - 0.033 13.7 0.0 0.037 13.5 0.0 1.0 1 0 0 1 1 1 0 Adenovirus endoprotease LRR_8 PF13855.1 KNZ76116.1 - 2.6 7.8 7.2 11 5.8 2.0 3.2 2 1 0 3 3 3 0 Leucine rich repeat Aldo_ket_red PF00248.16 KNZ76117.1 - 1.6e-71 240.3 0.0 2e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 KNZ76117.1 - 0.23 11.4 0.8 0.84 9.6 0.0 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family GPI-anchored PF10342.4 KNZ76118.1 - 2e-10 40.9 1.6 3.8e-10 40.0 0.1 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Amidase PF01425.16 KNZ76119.1 - 1.9e-95 320.3 0.0 2.2e-95 320.0 0.0 1.0 1 0 0 1 1 1 1 Amidase ABC2_membrane PF01061.19 KNZ76120.1 - 1.1e-80 269.8 47.0 1.2e-43 148.7 11.2 3.4 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.7 KNZ76120.1 - 1.9e-40 136.6 1.6 2.1e-30 104.4 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KNZ76120.1 - 2.7e-36 124.8 0.0 1.3e-17 64.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 KNZ76120.1 - 1.7e-08 34.0 0.0 0.00088 18.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain ABC_trans_N PF14510.1 KNZ76120.1 - 9.1e-07 28.8 0.0 2.1e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_22 PF13401.1 KNZ76120.1 - 9.9e-06 25.7 0.0 0.032 14.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KNZ76120.1 - 1.3e-05 25.2 0.0 0.00073 19.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KNZ76120.1 - 1.7e-05 24.0 0.0 0.00018 20.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 KNZ76120.1 - 9.1e-05 22.5 0.0 0.36 10.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KNZ76120.1 - 0.00026 20.4 0.3 0.049 13.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KNZ76120.1 - 0.00037 21.3 0.0 0.9 10.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KNZ76120.1 - 0.00049 20.4 0.0 0.69 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KNZ76120.1 - 0.00072 19.2 0.0 0.039 13.6 0.1 2.4 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 KNZ76120.1 - 0.0011 18.8 0.0 0.9 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KNZ76120.1 - 0.0022 17.5 0.0 0.72 9.2 0.0 2.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_19 PF13245.1 KNZ76120.1 - 0.0023 17.6 0.1 0.57 9.9 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain cobW PF02492.14 KNZ76120.1 - 0.0034 16.8 0.3 0.031 13.7 0.3 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 KNZ76120.1 - 0.0038 17.1 0.0 0.79 9.6 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 KNZ76120.1 - 0.0038 16.8 0.2 0.28 10.8 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 KNZ76120.1 - 0.0053 16.0 0.0 0.13 11.4 0.0 2.7 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KNZ76120.1 - 0.0082 16.0 0.0 0.82 9.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.2 KNZ76120.1 - 0.0083 15.1 54.0 0.0072 15.4 16.9 3.9 2 2 1 4 4 4 2 ABC-2 family transporter protein RNA_helicase PF00910.17 KNZ76120.1 - 0.016 15.3 0.0 0.8 9.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 KNZ76120.1 - 0.019 14.3 0.1 2.6 7.4 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 KNZ76120.1 - 0.02 14.5 0.0 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 KNZ76120.1 - 0.067 13.4 0.0 2.3 8.4 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KNZ76120.1 - 0.076 12.9 0.0 0.84 9.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KNZ76120.1 - 0.1 11.5 0.0 2.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.1 KNZ76120.1 - 0.12 11.4 0.0 2 7.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 KNZ76120.1 - 0.14 12.5 0.1 0.44 10.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 KNZ76120.1 - 0.15 11.6 0.0 2.5 7.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain Glyco_hydro_7 PF00840.15 KNZ76121.1 - 0.00025 19.5 0.0 0.00026 19.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Pkinase PF00069.20 KNZ76122.1 - 1.7e-31 109.3 0.0 8.9e-31 106.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ76122.1 - 1.1e-13 50.9 0.0 5.9e-06 25.5 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KNZ76122.1 - 0.01 15.5 1.8 0.041 13.6 0.2 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KNZ76122.1 - 0.15 10.9 0.0 2.5 6.9 0.0 2.4 3 0 0 3 3 3 0 Kinase-like E1-E2_ATPase PF00122.15 KNZ76123.1 - 8.7e-59 198.3 0.1 8.7e-59 198.3 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KNZ76123.1 - 1.3e-23 84.5 0.5 2.7e-23 83.5 0.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KNZ76123.1 - 4.3e-15 56.3 0.1 1.3e-14 54.7 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KNZ76123.1 - 1.3e-12 46.9 0.0 3.3e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KNZ76123.1 - 7e-05 22.5 0.0 0.0006 19.4 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phi-29_GP16_7 PF06720.6 KNZ76123.1 - 0.14 11.8 0.1 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 MFS_1 PF07690.11 KNZ76124.1 - 5.1e-39 133.9 25.3 6.2e-39 133.7 17.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily BTP PF05232.7 KNZ76124.1 - 3.6e-05 23.4 2.3 0.002 17.8 0.1 3.3 2 1 0 2 2 2 2 Bacterial Transmembrane Pair family NUDIX PF00293.23 KNZ76125.1 - 1.2e-15 57.3 0.3 1.6e-15 56.9 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain CsbD PF05532.7 KNZ76126.1 - 2.2e-08 33.6 14.8 0.00018 21.1 1.3 2.1 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.7 KNZ76126.1 - 0.029 14.4 1.4 0.05 13.6 0.8 1.7 1 1 0 1 1 1 0 Heat shock protein 9/12 MFS_1 PF07690.11 KNZ76127.1 - 1.1e-35 123.0 27.4 1.1e-35 123.0 19.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily BTP PF05232.7 KNZ76127.1 - 0.094 12.4 0.2 0.094 12.4 0.1 3.8 2 1 2 4 4 4 0 Bacterial Transmembrane Pair family UDP-g_GGTase PF06427.6 KNZ76128.1 - 3.8e-51 173.4 0.0 6.2e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KNZ76128.1 - 1.5e-07 31.0 0.0 2.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Peptidase_S66 PF02016.10 KNZ76128.1 - 0.17 10.8 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 LD-carboxypeptidase NMD3 PF04981.8 KNZ76129.1 - 2.3e-75 252.7 0.6 3e-75 252.3 0.4 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 KNZ76129.1 - 0.0028 17.4 4.1 0.012 15.4 1.7 2.4 2 1 0 2 2 2 1 Double zinc ribbon NinF PF05810.7 KNZ76129.1 - 0.053 13.3 1.4 0.12 12.2 0.3 2.1 2 0 0 2 2 2 0 NinF protein Rpr2 PF04032.11 KNZ76129.1 - 0.26 11.1 3.3 6.8 6.6 0.2 2.8 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GFA PF04828.9 KNZ76129.1 - 0.3 11.0 2.6 4 7.4 0.1 3.2 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_23 PF13489.1 KNZ76130.1 - 2.1e-11 43.7 0.0 2.9e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ76130.1 - 1.3e-07 31.9 0.0 2.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ76130.1 - 4e-05 24.0 0.0 0.00011 22.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ76130.1 - 5.3e-05 22.8 0.0 0.00016 21.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ76130.1 - 0.0003 21.3 0.0 0.00055 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Helitron_like_N PF14214.1 KNZ76134.1 - 0.00022 21.0 0.1 0.00037 20.2 0.1 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 KNZ76135.1 - 9.9e-54 182.6 0.4 1.4e-53 182.1 0.3 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ76135.1 - 1.6e-05 24.6 0.0 4.3e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 KNZ76135.1 - 0.0064 15.7 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.10 KNZ76135.1 - 0.061 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KNZ76135.1 - 0.094 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase APH PF01636.18 KNZ76136.1 - 2.9e-20 73.0 0.0 4.1e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ76136.1 - 2e-05 24.2 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase HipA_N PF07805.7 KNZ76136.1 - 0.072 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 HipA-like N-terminal domain RIO1 PF01163.17 KNZ76136.1 - 0.086 12.1 0.1 0.24 10.7 0.1 1.6 2 0 0 2 2 2 0 RIO1 family zf-CSL PF05207.8 KNZ76138.1 - 0.13 11.7 0.6 0.26 10.8 0.1 1.7 2 0 0 2 2 2 0 CSL zinc finger DUF676 PF05057.9 KNZ76139.1 - 3.5e-33 114.7 0.0 4.9e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KNZ76139.1 - 0.00011 21.7 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 KNZ76139.1 - 0.039 13.5 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Rtf2 PF04641.7 KNZ76140.1 - 3.4e-67 226.3 0.5 4e-67 226.1 0.4 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 KNZ76140.1 - 0.0018 17.9 0.5 0.22 11.2 0.1 2.6 1 1 1 2 2 2 2 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KNZ76140.1 - 0.0097 15.7 1.3 0.06 13.2 0.7 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zinc_ribbon_2 PF13240.1 KNZ76140.1 - 0.088 12.3 0.5 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 zinc-ribbon domain UPF0203 PF05254.7 KNZ76141.1 - 3.1e-17 62.1 3.0 2.3e-16 59.4 2.1 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 KNZ76141.1 - 0.043 13.7 3.3 1.9 8.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF19 PF01579.13 KNZ76141.1 - 0.14 12.1 1.3 0.3 11.0 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF19) Pet191_N PF10203.4 KNZ76141.1 - 0.25 11.4 1.8 3.9 7.6 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 KNZ76141.1 - 0.32 10.9 0.3 0.32 10.9 0.2 2.0 2 0 0 2 2 2 0 CHCH domain COX6B PF02297.12 KNZ76141.1 - 0.71 9.9 5.1 4.2 7.4 3.6 1.9 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb ADH_zinc_N PF00107.21 KNZ76142.1 - 2.4e-14 53.0 0.0 4.1e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ76142.1 - 3.8e-05 23.3 0.0 8.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CoA_binding_2 PF13380.1 KNZ76142.1 - 0.053 13.6 0.0 2.8 8.1 0.0 2.8 2 1 1 3 3 3 0 CoA binding domain HisG_C PF08029.6 KNZ76142.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 HisG, C-terminal domain EMP24_GP25L PF01105.19 KNZ76143.1 - 2.1e-45 154.6 0.0 2.5e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SCA7 PF08313.7 KNZ76144.1 - 3.7e-28 96.9 0.1 3.7e-28 96.9 0.1 2.0 2 0 0 2 2 2 1 SCA7, zinc-binding domain Sgf11 PF08209.6 KNZ76144.1 - 0.0014 17.8 0.1 0.003 16.8 0.1 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-TRAF PF02176.13 KNZ76144.1 - 0.0041 17.4 1.3 0.02 15.2 0.1 2.4 2 0 0 2 2 2 1 TRAF-type zinc finger TFIID_30kDa PF03540.8 KNZ76145.1 - 9.8e-27 92.5 0.1 1.4e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Ribosomal_60s PF00428.14 KNZ76145.1 - 0.0048 17.2 4.1 0.71 10.3 0.0 2.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein Bromo_TP PF07524.8 KNZ76145.1 - 0.048 13.3 0.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Bromodomain associated DUF3464 PF11947.3 KNZ76145.1 - 0.086 12.2 0.1 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Ribosomal_L11_N PF03946.9 KNZ76145.1 - 0.096 12.1 0.1 8.4 5.9 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain DUF2360 PF10152.4 KNZ76145.1 - 0.19 12.0 3.5 0.29 11.4 2.4 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF959 PF06121.9 KNZ76145.1 - 1.1 8.8 6.5 1.4 8.4 4.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) Fungal_trans PF04082.13 KNZ76146.1 - 8.9e-19 67.3 0.5 8.9e-19 67.3 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Xylanase PF13201.1 KNZ76146.1 - 0.19 10.5 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Putative glycoside hydrolase xylanase RNA_pol_Rpc4 PF05132.9 KNZ76147.1 - 3.7e-24 85.1 0.8 1.5e-23 83.2 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase III RPC4 Pribosyltran PF00156.22 KNZ76148.1 - 2.8e-10 40.0 0.0 4.8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Aconitase PF00330.15 KNZ76149.1 - 4e-71 239.9 1.4 6.3e-41 140.3 0.0 3.1 2 1 1 3 3 3 3 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KNZ76149.1 - 1.8e-19 70.1 0.0 3.4e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain SRPRB PF09439.5 KNZ76150.1 - 1e-21 76.9 0.0 1.6e-21 76.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KNZ76150.1 - 6.5e-14 51.5 0.0 9.3e-14 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KNZ76150.1 - 6.1e-09 35.8 0.0 9.5e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KNZ76150.1 - 3e-08 33.1 0.0 3.7e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KNZ76150.1 - 3e-06 27.7 0.0 5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_25 PF13481.1 KNZ76150.1 - 0.00095 18.6 0.1 0.002 17.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 KNZ76150.1 - 0.002 17.5 0.0 1.3 8.3 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KNZ76150.1 - 0.012 15.6 0.6 0.023 14.6 0.4 1.7 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 KNZ76150.1 - 0.016 14.5 0.1 0.06 12.6 0.0 2.0 2 1 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.15 KNZ76150.1 - 0.029 13.0 0.0 1.2 7.7 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.1 KNZ76150.1 - 0.069 13.2 0.0 0.14 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KNZ76150.1 - 0.075 13.2 0.0 0.15 12.2 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 KNZ76150.1 - 0.13 11.7 0.1 11 5.4 0.0 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ENTH PF01417.15 KNZ76151.1 - 8.9e-52 174.1 0.1 1.6e-51 173.3 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KNZ76151.1 - 7.9e-05 21.4 0.0 7.9e-05 21.4 0.0 2.3 2 0 0 2 2 2 1 ANTH domain PAT1 PF09770.4 KNZ76151.1 - 0.27 9.4 46.4 0.4 8.8 32.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pox_P4B PF03292.9 KNZ76151.1 - 0.51 8.2 3.5 0.89 7.4 2.4 1.3 1 0 0 1 1 1 0 Poxvirus P4B major core protein DUF1421 PF07223.6 KNZ76151.1 - 2.3 7.9 52.2 3.9 7.1 36.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) Peptidase_S64 PF08192.6 KNZ76151.1 - 2.5 6.3 13.3 4.2 5.5 9.2 1.3 1 0 0 1 1 1 0 Peptidase family S64 Pkinase PF00069.20 KNZ76152.1 - 4.8e-61 206.1 0.0 7.4e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ76152.1 - 3.4e-30 105.0 0.0 5.4e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ76152.1 - 7.5e-08 31.6 0.0 1.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KNZ76152.1 - 0.00056 19.0 0.6 0.0026 16.8 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KNZ76152.1 - 0.0025 16.7 0.1 0.39 9.4 0.0 2.2 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase APH PF01636.18 KNZ76152.1 - 0.0025 17.6 0.2 0.0049 16.6 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KNZ76152.1 - 0.063 12.6 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Guanylate_kin PF00625.16 KNZ76153.1 - 1.2e-63 213.9 0.0 1.5e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 KNZ76153.1 - 4.5e-08 33.2 0.1 8.8e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KNZ76153.1 - 2.3e-07 30.7 0.0 4.8e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KNZ76153.1 - 4e-05 23.7 0.1 0.00026 21.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KNZ76153.1 - 0.00048 19.3 0.0 0.00071 18.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KNZ76153.1 - 0.0006 19.5 0.0 0.0031 17.2 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 KNZ76153.1 - 0.002 18.9 0.0 0.0037 18.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KNZ76153.1 - 0.0035 17.3 0.0 0.0054 16.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 KNZ76153.1 - 0.0049 17.0 0.0 0.0083 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 KNZ76153.1 - 0.0083 16.0 0.0 0.017 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KNZ76153.1 - 0.0086 16.3 0.0 0.011 16.0 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.1 KNZ76153.1 - 0.0091 15.6 0.0 0.034 13.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KNZ76153.1 - 0.012 15.9 0.1 0.045 14.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KNZ76153.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KNZ76153.1 - 0.013 15.1 0.0 0.071 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Miro PF08477.8 KNZ76153.1 - 0.017 15.6 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA PF00004.24 KNZ76153.1 - 0.025 14.7 0.0 0.083 13.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KNZ76153.1 - 0.044 13.1 0.0 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KNZ76153.1 - 0.044 13.2 0.1 0.058 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA-like domain KAP_NTPase PF07693.9 KNZ76153.1 - 0.05 12.5 0.0 0.25 10.2 0.0 1.9 1 1 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.7 KNZ76153.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 KNZ76153.1 - 0.06 13.3 0.0 0.2 11.6 0.0 1.9 2 1 0 2 2 2 0 AAA domain WEMBL PF05701.6 KNZ76153.1 - 0.12 10.8 0.2 0.16 10.4 0.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light ABC_membrane PF00664.18 KNZ76154.1 - 9.1e-60 202.3 39.1 3.3e-34 118.5 7.1 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 KNZ76154.1 - 4.2e-54 182.5 0.0 2.6e-31 108.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 KNZ76154.1 - 3.2e-07 30.5 0.3 0.0068 16.4 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KNZ76154.1 - 2.6e-06 26.8 0.0 0.072 12.3 0.0 3.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KNZ76154.1 - 6.4e-06 26.3 0.1 0.0055 16.6 0.0 3.5 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 KNZ76154.1 - 2e-05 25.0 0.2 0.26 11.7 0.1 2.8 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 KNZ76154.1 - 9.9e-05 22.2 0.0 0.42 10.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 KNZ76154.1 - 0.00024 20.5 0.0 0.63 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KNZ76154.1 - 0.00041 19.8 0.2 0.57 9.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KNZ76154.1 - 0.00075 18.4 0.1 0.22 10.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.18 KNZ76154.1 - 0.0047 16.7 0.4 2.9 7.6 0.1 2.4 2 0 0 2 2 2 2 Dynamin family Zeta_toxin PF06414.7 KNZ76154.1 - 0.0057 15.7 0.4 1 8.4 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 KNZ76154.1 - 0.0068 15.6 0.2 2.2 7.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KNZ76154.1 - 0.0095 16.2 0.0 5.7 7.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KNZ76154.1 - 0.013 15.1 0.4 4 6.9 0.1 3.0 2 1 0 2 2 2 0 AAA domain cobW PF02492.14 KNZ76154.1 - 0.033 13.6 1.2 0.49 9.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KNZ76154.1 - 0.046 13.8 1.0 1.8 8.7 0.0 3.1 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 KNZ76154.1 - 0.071 11.8 0.3 4.3 6.0 0.1 2.3 2 0 0 2 2 2 0 ArgK protein UPF0079 PF02367.12 KNZ76154.1 - 0.3 10.7 1.2 0.78 9.3 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF87 PF01935.12 KNZ76154.1 - 2.2 8.0 7.9 2.8 7.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 SDH_alpha PF03313.10 KNZ76156.1 - 5.5e-83 278.2 0.1 1e-82 277.3 0.1 1.4 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 KNZ76156.1 - 1.3e-40 139.0 0.0 3.6e-40 137.5 0.0 1.8 1 1 0 1 1 1 1 Serine dehydratase beta chain Clathrin PF00637.15 KNZ76157.1 - 4.5e-205 671.4 29.0 1.3e-32 112.3 0.2 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 KNZ76157.1 - 1.6e-37 125.2 4.0 3.4e-05 23.8 0.0 7.7 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.1 KNZ76157.1 - 8.9e-29 99.1 0.0 2.3e-28 97.8 0.0 1.8 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 KNZ76157.1 - 3.1e-10 38.8 0.5 1.1e-09 37.1 0.1 2.3 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_7 PF13176.1 KNZ76157.1 - 0.0057 16.3 7.5 4.7 7.2 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.15 KNZ76157.1 - 0.022 14.7 0.2 9.1 6.5 0.0 5.0 6 0 0 6 6 5 0 PPR repeat TPR_14 PF13428.1 KNZ76157.1 - 0.023 15.3 8.1 4 8.3 0.0 7.3 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ76157.1 - 0.057 13.3 7.2 6 6.9 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ76157.1 - 0.1 12.5 13.1 1.2 9.0 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ76157.1 - 0.11 12.2 7.0 14 5.5 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ76157.1 - 0.21 11.5 10.6 37 4.5 0.3 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Ras PF00071.17 KNZ76158.1 - 4.7e-48 162.6 0.0 5.4e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ76158.1 - 9.9e-14 51.8 0.0 1.3e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ76158.1 - 0.00038 19.7 0.0 0.00044 19.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KNZ76158.1 - 0.0096 15.1 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KNZ76158.1 - 0.021 14.7 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KNZ76158.1 - 0.05 12.7 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF1640 PF07798.6 KNZ76159.1 - 8.6e-65 218.0 9.6 9.7e-65 217.9 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF2077 PF09850.4 KNZ76159.1 - 0.11 11.8 2.6 2.3 7.5 0.0 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) COG5 PF10392.4 KNZ76159.1 - 1 9.3 6.4 2.1 8.3 0.4 2.9 1 1 2 3 3 3 0 Golgi transport complex subunit 5 DivIC PF04977.10 KNZ76159.1 - 2 7.9 9.1 0.64 9.5 2.9 2.2 1 1 2 3 3 3 0 Septum formation initiator Nbl1_Borealin_N PF10444.4 KNZ76159.1 - 2.1 7.7 6.5 0.38 10.1 0.3 2.6 3 1 0 3 3 3 0 Nbl1 / Borealin N terminal FlaC_arch PF05377.6 KNZ76159.1 - 3.1 7.7 5.9 1.8 8.5 0.5 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Nup54 PF13874.1 KNZ76159.1 - 6 6.5 10.2 2.5 7.7 5.2 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Peptidase_C12 PF01088.16 KNZ76160.1 - 3.7e-51 173.3 0.0 6.1e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 WD40 PF00400.27 KNZ76160.1 - 5.5e-24 83.1 9.5 2.6e-06 27.0 0.2 6.5 5 1 1 6 6 6 4 WD domain, G-beta repeat TPR_11 PF13414.1 KNZ76161.1 - 4.9e-10 38.9 0.5 2e-08 33.7 0.0 2.6 2 0 0 2 2 2 1 TPR repeat UBA PF00627.26 KNZ76161.1 - 0.00041 20.1 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.12 KNZ76161.1 - 0.0027 17.4 2.3 11 6.2 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ76161.1 - 0.02 14.4 1.1 31 4.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.26 KNZ76161.1 - 0.034 13.8 0.1 0.3 10.8 0.0 2.5 3 0 0 3 3 3 0 DnaJ domain TPR_12 PF13424.1 KNZ76161.1 - 0.083 12.8 0.2 0.27 11.2 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Chromo PF00385.19 KNZ76162.1 - 3.6e-10 39.3 0.0 7e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KNZ76162.1 - 0.002 17.7 0.0 0.0031 17.1 0.0 1.5 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Terpene_synth_C PF03936.11 KNZ76164.1 - 0.0077 15.4 0.0 0.0088 15.3 0.0 1.0 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Glyco_hydro_88 PF07470.8 KNZ76165.1 - 8.2e-19 67.8 0.1 1.1e-18 67.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Colicin_C PF12106.3 KNZ76165.1 - 0.17 11.4 1.2 0.35 10.4 0.8 1.5 1 0 0 1 1 1 0 Colicin C terminal ribonuclease domain SET PF00856.23 KNZ76166.1 - 2.7e-10 40.8 0.0 4.9e-08 33.4 0.0 2.3 1 1 0 1 1 1 1 SET domain Sod_Fe_C PF02777.13 KNZ76168.1 - 2.6e-35 120.4 0.1 4.4e-35 119.7 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KNZ76168.1 - 7.3e-32 109.4 4.2 8.3e-32 109.2 1.6 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ATP-synt_DE PF00401.15 KNZ76168.1 - 0.4 10.6 6.8 0.41 10.5 2.6 2.1 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain PIF1 PF05970.9 KNZ76169.1 - 2.6e-27 95.7 0.0 2.9e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 KNZ76170.1 - 1e-05 23.5 0.0 1.1e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Helicase EAF PF09816.4 KNZ76171.1 - 0.1 12.5 0.2 0.19 11.7 0.1 1.5 1 1 0 1 1 1 0 RNA polymerase II transcription elongation factor RVP_2 PF08284.6 KNZ76172.1 - 0.021 14.7 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Aldo_ket_red PF00248.16 KNZ76174.1 - 6.4e-37 126.9 0.0 7.4e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3089 PF11288.3 KNZ76175.1 - 0.0022 17.1 0.0 0.0047 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Pectate_lyase_3 PF12708.2 KNZ76178.1 - 7e-70 235.6 20.2 1.1e-52 179.4 4.3 3.3 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KNZ76178.1 - 0.0049 16.2 0.1 0.028 13.9 0.1 2.4 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase Lactamase_B_2 PF12706.2 KNZ76178.1 - 0.023 14.2 0.0 0.072 12.6 0.0 1.9 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Nup84_Nup100 PF04121.8 KNZ76179.1 - 8.2e-82 274.9 0.0 1.5e-80 270.8 0.0 2.3 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Nic96 PF04097.9 KNZ76179.1 - 7.3e-05 21.1 0.3 0.00013 20.2 0.0 1.5 2 0 0 2 2 2 1 Nup93/Nic96 TPR_14 PF13428.1 KNZ76179.1 - 8 7.3 8.9 4.2 8.2 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Asp_protease_2 PF13650.1 KNZ76182.1 - 9.1e-07 29.2 0.0 1.6e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ76182.1 - 0.00046 19.7 0.1 0.00064 19.2 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 KNZ76182.1 - 0.054 13.4 0.1 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1758 PF05585.7 KNZ76182.1 - 0.065 12.7 0.2 0.2 11.1 0.1 1.7 1 1 1 2 2 2 0 Putative peptidase (DUF1758) gag-asp_proteas PF13975.1 KNZ76182.1 - 0.088 12.6 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Sugarporin_N PF11471.3 KNZ76183.1 - 0.1 12.2 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF4063 PF13272.1 KNZ76184.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4063) Calcyon PF06387.6 KNZ76184.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) Chromo PF00385.19 KNZ76185.1 - 0.13 12.0 1.5 0.15 11.7 1.1 1.1 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain FHA PF00498.21 KNZ76186.1 - 1.5e-15 57.0 0.3 5.3e-15 55.2 0.0 2.2 2 1 0 2 2 2 1 FHA domain Lipoprotein_7 PF01540.11 KNZ76186.1 - 0.00075 18.6 0.2 0.0015 17.7 0.1 1.4 1 0 0 1 1 1 1 Adhesin lipoprotein DUF1664 PF07889.7 KNZ76186.1 - 0.02 14.7 5.5 1.8 8.3 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 KNZ76186.1 - 0.4 10.7 7.6 0.65 10.1 0.0 3.2 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family PspA_IM30 PF04012.7 KNZ76186.1 - 0.86 8.9 21.9 0.94 8.7 7.2 2.6 2 0 0 2 2 2 0 PspA/IM30 family TPR_MLP1_2 PF07926.7 KNZ76186.1 - 1.8 8.2 24.1 2.2 8.0 3.5 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Borrelia_REV PF03978.8 KNZ76186.1 - 2 8.1 4.9 0.38 10.4 0.2 2.2 3 0 0 3 3 3 0 Borrelia burgdorferi REV protein Reo_sigmaC PF04582.7 KNZ76186.1 - 2.3 7.3 6.6 1.5 7.9 1.5 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF972 PF06156.8 KNZ76186.1 - 4.6 7.6 12.8 13 6.1 0.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Prefoldin_2 PF01920.15 KNZ76186.1 - 6.4 6.6 18.1 0.45 10.2 0.5 4.0 3 1 1 4 4 4 0 Prefoldin subunit WW PF00397.21 KNZ76187.1 - 4.9e-07 29.4 4.8 1.2e-06 28.2 3.3 1.7 1 0 0 1 1 1 1 WW domain Glyco_hydro_28 PF00295.12 KNZ76189.1 - 9.4e-34 116.8 2.1 1.3e-33 116.3 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 UQ_con PF00179.21 KNZ76190.1 - 3.1e-44 149.7 0.1 3.6e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KNZ76190.1 - 4.3e-07 29.7 0.1 4.5e-06 26.4 0.0 1.9 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 KNZ76190.1 - 0.068 13.0 0.1 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 RWD domain EMP24_GP25L PF01105.19 KNZ76191.1 - 1.4e-41 142.2 0.0 1.7e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD KRE9 PF05390.6 KNZ76192.1 - 0.054 13.8 0.5 0.31 11.4 0.0 2.1 2 0 0 2 2 2 0 Yeast cell wall synthesis protein KRE9/KNH1 RNase_PH PF01138.16 KNZ76193.1 - 6.9e-22 78.1 0.0 1.1e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_M24 PF00557.19 KNZ76194.1 - 1.7e-55 187.8 0.0 2.2e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KNZ76194.1 - 6.5e-16 57.9 0.0 1.1e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Use1 PF09753.4 KNZ76195.1 - 4.5e-13 49.2 3.4 8e-13 48.4 2.4 1.8 1 1 0 1 1 1 1 Membrane fusion protein Use1 Rhabdo_glycop PF00974.13 KNZ76195.1 - 0.1 10.8 0.1 0.14 10.4 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein GP41 PF00517.12 KNZ76195.1 - 0.1 12.1 0.3 0.21 11.1 0.2 1.5 1 0 0 1 1 1 0 Retroviral envelope protein DUF948 PF06103.6 KNZ76195.1 - 0.31 10.9 2.0 12 5.8 0.5 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_11 PF13414.1 KNZ76196.1 - 2.9e-14 52.4 0.0 4e-10 39.1 0.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 KNZ76196.1 - 1.9e-07 31.5 0.2 0.0045 17.6 0.0 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ76196.1 - 5.6e-07 29.2 0.0 0.55 10.5 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ76196.1 - 2.7e-06 26.8 0.1 0.064 13.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ76196.1 - 5.6e-06 25.7 0.0 0.29 10.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ76196.1 - 7.7e-06 25.6 0.3 1.5e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ76196.1 - 0.0007 20.0 0.1 0.0026 18.2 0.1 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ76196.1 - 0.0088 16.3 0.3 2.4 8.5 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat Prenyltrans PF00432.16 KNZ76197.1 - 1.1e-39 133.6 7.5 9.9e-10 37.8 0.3 6.4 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KNZ76197.1 - 2e-21 76.5 0.0 1.2e-16 61.0 0.0 3.4 2 1 1 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 KNZ76197.1 - 2.7e-05 24.1 0.0 0.00048 20.1 0.0 2.8 2 1 1 3 3 3 1 Prenyltransferase-like Ribosomal_S10 PF00338.17 KNZ76198.1 - 5.2e-23 80.7 0.0 8.3e-23 80.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L23 PF00276.15 KNZ76199.1 - 1.7e-19 69.5 1.5 2.4e-19 69.0 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 ASL_C PF08328.6 KNZ76199.1 - 0.033 14.0 0.1 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Nop53 PF07767.6 KNZ76200.1 - 1e-77 261.7 22.0 1.2e-77 261.4 15.2 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) APC_crr PF05923.7 KNZ76200.1 - 0.34 10.6 1.3 0.66 9.6 0.9 1.5 1 0 0 1 1 1 0 APC cysteine-rich region CBF PF03914.12 KNZ76201.1 - 3.1e-31 108.0 0.0 3.1e-31 108.0 0.0 2.4 3 0 0 3 3 3 1 CBF/Mak21 family Aminotran_1_2 PF00155.16 KNZ76202.1 - 2.1e-42 145.3 0.0 2.8e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II TFIIIC_sub6 PF10419.4 KNZ76203.1 - 1.7e-05 24.1 0.0 2.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit TT_ORF2 PF02957.10 KNZ76203.1 - 0.2 12.3 4.6 8.2 7.1 1.5 2.2 2 0 0 2 2 2 0 TT viral ORF2 FtsJ PF01728.14 KNZ76204.1 - 1.1e-17 64.5 0.0 1.8e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 KNZ76204.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain BNIP2 PF12496.3 KNZ76205.1 - 0.039 14.1 1.1 0.054 13.6 0.7 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 BNIP2 PF12496.3 KNZ76206.1 - 0.029 14.5 1.8 0.04 14.0 1.2 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF3169 PF11368.3 KNZ76206.1 - 0.27 10.3 2.4 0.8 8.8 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) BAR_2 PF10455.4 KNZ76209.1 - 6.4e-12 44.9 0.7 7.9e-12 44.6 0.5 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking PAP_fibrillin PF04755.7 KNZ76209.1 - 0.019 14.6 0.1 0.024 14.3 0.1 1.1 1 0 0 1 1 1 0 PAP_fibrillin DUF4451 PF14616.1 KNZ76210.1 - 2.5e-14 53.1 0.7 2.9e-14 52.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Put_DNA-bind_N PF06971.8 KNZ76211.1 - 0.25 11.1 0.7 12 5.7 0.0 2.6 3 0 0 3 3 3 0 Putative DNA-binding protein N-terminus HATPase_c PF02518.21 KNZ76212.1 - 0.027 14.1 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Arabinose_bd PF12625.2 KNZ76212.1 - 0.028 14.2 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Arabinose-binding domain of AraC transcription regulator, N-term HATPase_c_3 PF13589.1 KNZ76212.1 - 0.036 13.7 2.2 0.33 10.6 0.1 2.8 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NusG PF02357.14 KNZ76212.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Transcription termination factor nusG DUF4449 PF14613.1 KNZ76213.1 - 2.7e-23 82.6 1.4 3.4e-22 79.1 0.0 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) Spectrin PF00435.16 KNZ76213.1 - 0.091 13.0 0.4 0.091 13.0 0.3 3.7 4 0 0 4 4 4 0 Spectrin repeat Apolipoprotein PF01442.13 KNZ76213.1 - 0.15 11.5 9.9 7.2 6.0 0.1 3.8 3 1 1 4 4 4 0 Apolipoprotein A1/A4/E domain Mago_nashi PF02792.9 KNZ76214.1 - 1e-75 252.1 0.3 1.2e-75 251.9 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.3 KNZ76214.1 - 0.1 12.3 0.2 0.14 11.9 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3506) Histone PF00125.19 KNZ76215.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNZ76215.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KNZ76215.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KNZ76215.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KNZ76215.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KNZ76215.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit FtsJ PF01728.14 KNZ76216.1 - 8.8e-47 159.4 0.0 1.1e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase MFS_1 PF07690.11 KNZ76217.1 - 6.6e-17 61.2 47.8 5.1e-15 55.0 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 KNZ76218.1 - 2.8e-31 106.2 22.4 8.1e-08 31.8 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF3337 PF11816.3 KNZ76218.1 - 2.5e-29 102.7 0.9 4.3e-25 88.8 0.9 3.2 2 1 0 2 2 2 2 Domain of unknown function (DUF3337) Nup160 PF11715.3 KNZ76218.1 - 0.038 12.1 3.4 0.32 9.0 0.2 3.0 1 1 1 3 3 3 0 Nucleoporin Nup120/160 PWWP PF00855.12 KNZ76223.1 - 2.6e-16 59.6 0.5 5.6e-16 58.5 0.3 1.7 1 1 0 1 1 1 1 PWWP domain Ebola_NP PF05505.7 KNZ76223.1 - 2 6.4 8.5 0.7 7.8 3.9 1.6 2 0 0 2 2 2 0 Ebola nucleoprotein Ricin_B_lectin PF00652.17 KNZ76224.1 - 5.4e-20 71.6 1.5 9.3e-20 70.9 1.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KNZ76224.1 - 1.1e-15 57.8 2.2 1.3e-09 38.4 0.7 2.8 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Asp PF00026.18 KNZ76226.1 - 2.2e-43 148.7 0.2 5.6e-43 147.3 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNZ76226.1 - 8.5e-05 22.5 0.1 0.0034 17.3 0.0 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KNZ76226.1 - 0.0056 16.2 0.1 0.084 12.4 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KNZ76226.1 - 0.023 15.1 0.9 1.6 9.3 0.1 3.1 3 1 0 3 3 3 0 Aspartyl protease Iso_dh PF00180.15 KNZ76227.1 - 2.7e-83 279.8 0.0 3e-83 279.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2618 PF10940.3 KNZ76228.1 - 0.039 13.7 0.7 0.69 9.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2618) Tcf25 PF04910.9 KNZ76229.1 - 4.1e-61 206.9 0.1 1.1e-60 205.5 0.0 1.6 2 0 0 2 2 2 1 Transcriptional repressor TCF25 TPR_12 PF13424.1 KNZ76229.1 - 0.012 15.5 0.1 0.041 13.8 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ76229.1 - 0.1 13.2 3.7 0.51 11.1 0.5 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ76229.1 - 0.67 9.9 5.9 0.067 13.1 0.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_phi PF04931.8 KNZ76229.1 - 0.75 7.4 7.3 1.2 6.8 5.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF2217 PF10265.4 KNZ76229.1 - 1.3 7.6 3.1 2.1 7.0 2.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Sugar_tr PF00083.19 KNZ76230.1 - 1.1e-38 133.0 22.9 3e-28 98.6 10.6 2.8 1 1 2 3 3 3 2 Sugar (and other) transporter DUF3808 PF10300.4 KNZ76231.1 - 1.2e-60 205.4 0.0 8.5e-37 126.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3808) TPR_11 PF13414.1 KNZ76231.1 - 3.4e-07 29.8 0.1 0.001 18.7 0.0 3.4 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 KNZ76231.1 - 1e-06 28.9 1.8 9.4e-05 22.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ76231.1 - 2.8e-06 27.8 0.7 0.11 13.1 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ76231.1 - 6.1e-06 25.7 6.1 0.7 9.9 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ76231.1 - 6.5e-05 22.4 0.2 0.098 12.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ76231.1 - 0.0003 20.6 2.7 3.2 7.7 0.1 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KNZ76231.1 - 0.00056 19.9 1.0 0.003 17.6 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KNZ76231.1 - 0.00095 18.6 0.4 1.5 8.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ76231.1 - 0.0033 17.7 3.4 16 6.2 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ76231.1 - 0.086 13.5 11.3 14 6.6 0.0 5.3 4 1 2 6 6 5 0 Tetratricopeptide repeat Kdo PF06293.9 KNZ76234.1 - 0.0021 17.1 0.0 0.0038 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DCR PF14047.1 KNZ76234.1 - 0.044 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Dppa2/4 conserved region YppG PF14179.1 KNZ76235.1 - 0.46 11.0 5.2 0.83 10.2 3.6 1.4 1 0 0 1 1 1 0 YppG-like protein Amidohydro_4 PF13147.1 KNZ76236.1 - 2.3e-15 57.3 6.3 1.6e-07 31.6 0.0 4.4 4 1 0 4 4 4 2 Amidohydrolase Amidohydro_5 PF13594.1 KNZ76236.1 - 2.4e-11 43.2 0.2 8.6e-09 35.0 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KNZ76236.1 - 2.4e-10 40.6 0.0 1.2e-05 25.1 0.0 3.3 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_3 PF07969.6 KNZ76236.1 - 4.2e-06 26.2 0.3 0.0006 19.1 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family DUF1825 PF08855.5 KNZ76237.1 - 0.21 11.6 2.9 2.2 8.3 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) Gtr1_RagA PF04670.7 KNZ76237.1 - 0.66 9.0 8.9 0.81 8.7 0.1 2.8 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region GTPase_Cys_C PF12631.2 KNZ76237.1 - 3.5 8.1 6.9 3 8.3 0.1 3.7 3 0 0 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DIOX_N PF14226.1 KNZ76238.1 - 3.3e-16 59.8 0.0 7.3e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KNZ76238.1 - 9.4e-15 54.7 0.0 8.3e-14 51.6 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_16 PF00722.16 KNZ76239.1 - 1.8e-19 69.7 0.3 6.1e-19 68.0 0.1 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 KNZ76240.1 - 3e-50 170.6 0.3 3e-50 170.6 0.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KNZ76240.1 - 7.5e-11 42.2 0.0 2.8e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KNZ76240.1 - 0.0061 16.2 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 ADH_zinc_N PF00107.21 KNZ76241.1 - 8e-22 77.1 0.2 1.7e-21 76.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KNZ76241.1 - 8.6e-12 46.0 0.0 1.7e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ76241.1 - 7.7e-07 28.8 0.1 6.3e-06 25.9 0.0 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain MitMem_reg PF13012.1 KNZ76242.1 - 2.3e-36 124.3 0.2 5.7e-36 123.0 0.1 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KNZ76242.1 - 2.5e-26 91.6 0.4 6.3e-26 90.3 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Adenosine_kin PF04008.9 KNZ76242.1 - 0.038 13.4 0.1 0.081 12.4 0.0 1.7 2 0 0 2 2 2 0 Adenosine specific kinase zf-CCHC PF00098.18 KNZ76243.1 - 4.8e-33 111.5 42.2 7e-08 32.0 1.5 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_4 PF14392.1 KNZ76243.1 - 0.00016 21.2 29.1 0.098 12.3 0.5 5.4 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_3 PF13917.1 KNZ76243.1 - 0.00027 20.6 28.8 0.12 12.1 0.2 5.2 3 2 3 6 6 6 4 Zinc knuckle zf-CCHC_6 PF15288.1 KNZ76243.1 - 0.0015 18.1 29.1 0.026 14.1 4.2 5.0 4 1 1 5 5 5 3 Zinc knuckle Clusterin PF01093.12 KNZ76243.1 - 0.99 8.1 3.5 1 8.0 2.4 1.1 1 0 0 1 1 1 0 Clusterin zf-CCHC_2 PF13696.1 KNZ76243.1 - 4.8 6.7 30.2 0.75 9.3 0.2 5.8 2 2 4 6 6 6 0 Zinc knuckle Peptidase_M43 PF05572.8 KNZ76244.1 - 4.2e-17 62.1 0.0 1.1e-16 60.8 0.0 1.6 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 KNZ76244.1 - 4.8e-05 23.3 0.0 7e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KNZ76244.1 - 0.00015 21.8 0.2 0.00025 21.1 0.1 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KNZ76244.1 - 0.00038 20.0 0.0 0.00053 19.5 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KNZ76244.1 - 0.0012 19.3 0.0 0.0023 18.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KNZ76244.1 - 0.074 12.7 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.4 KNZ76244.1 - 0.11 11.3 0.1 0.18 10.6 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M7 PF02031.11 KNZ76244.1 - 0.15 11.8 1.3 0.22 11.2 0.2 1.9 2 1 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Ctr PF04145.10 KNZ76245.1 - 6e-18 65.2 0.5 7.8e-18 64.8 0.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family ATP-synt_Eps PF04627.8 KNZ76246.1 - 3.9e-18 64.7 1.3 5.2e-18 64.3 0.9 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Ras PF00071.17 KNZ76247.1 - 5.3e-51 172.2 0.0 6.1e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ76247.1 - 3e-14 53.5 0.0 4.7e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ76247.1 - 1.4e-12 47.1 0.0 1.7e-12 46.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KNZ76247.1 - 2.2e-05 23.9 0.0 0.00055 19.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KNZ76247.1 - 0.00022 21.1 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KNZ76247.1 - 0.12 12.1 0.0 0.35 10.6 0.0 1.7 3 0 0 3 3 3 0 Dynamin family DSPc PF00782.15 KNZ76248.1 - 5.2e-24 84.3 0.0 6.2e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KNZ76248.1 - 0.0051 16.1 0.0 0.0059 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KNZ76248.1 - 0.0062 15.4 0.0 0.0062 15.4 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DEAD PF00270.24 KNZ76249.1 - 9.9e-20 70.7 0.0 1.3e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.1 KNZ76249.1 - 0.028 13.4 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MFS_1 PF07690.11 KNZ76250.1 - 2.8e-26 92.0 68.7 4e-18 65.2 27.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KNZ76250.1 - 0.0039 16.9 3.3 0.2 11.4 1.2 2.7 2 0 0 2 2 2 2 MFS_1 like family Fibrillarin PF01269.12 KNZ76251.1 - 1.3e-109 364.5 0.0 1.5e-109 364.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KNZ76251.1 - 0.00028 20.4 0.0 0.00043 19.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KNZ76251.1 - 0.0068 15.9 0.1 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KNZ76251.1 - 0.0086 15.6 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PMT PF02366.13 KNZ76252.1 - 9.7e-80 267.4 18.5 9.7e-80 267.4 12.8 2.4 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KNZ76252.1 - 4.5e-30 104.6 1.0 6.3e-30 104.1 0.7 1.2 1 0 0 1 1 1 1 MIR domain DUF3760 PF12586.3 KNZ76252.1 - 0.078 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) VPS28 PF03997.7 KNZ76254.1 - 3.9e-59 199.4 0.0 4.6e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein adh_short PF00106.20 KNZ76255.1 - 3.2e-20 72.7 0.0 4.2e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ76255.1 - 4.5e-09 36.2 0.0 7.5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KNZ76255.1 - 6.1e-07 29.1 0.1 2.1e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ76255.1 - 4.3e-05 23.6 0.1 4.8e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KNZ76255.1 - 0.0045 16.7 0.3 0.013 15.2 0.3 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Exo_endo_phos PF03372.18 KNZ76256.1 - 7.9e-07 29.2 0.8 1.2e-06 28.6 0.5 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.12 KNZ76256.1 - 1.7e-05 24.7 0.0 3.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain PIF1 PF05970.9 KNZ76259.1 - 1.5e-60 205.1 0.0 1.6e-60 204.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ76259.1 - 0.043 13.3 0.0 0.075 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KNZ76259.1 - 0.044 13.2 0.1 0.11 12.0 0.1 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.6 KNZ76259.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Torsin RNA_helicase PF00910.17 KNZ76259.1 - 0.11 12.6 0.1 0.53 10.4 0.1 2.0 1 1 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 KNZ76261.1 - 1.7e-06 28.0 0.1 4.1e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KNZ76261.1 - 0.00016 22.1 0.1 0.00039 20.9 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 KNZ76261.1 - 0.0033 16.6 0.0 0.0079 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 KNZ76261.1 - 0.03 13.3 0.3 0.12 11.3 0.1 1.9 1 1 1 2 2 2 0 Septin AIG1 PF04548.11 KNZ76261.1 - 0.033 13.3 0.1 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 AIG1 family cobW PF02492.14 KNZ76261.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.8 KNZ76261.1 - 0.065 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2326 PF10088.4 KNZ76261.1 - 0.096 12.3 0.2 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2326) T2SE PF00437.15 KNZ76261.1 - 0.13 11.1 0.0 0.47 9.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 KNZ76261.1 - 0.24 11.2 1.2 5.8 6.7 0.4 2.3 1 1 1 2 2 2 0 Dynamin family G-alpha PF00503.15 KNZ76262.1 - 1.2e-05 24.1 0.1 0.00038 19.2 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit Miro PF08477.8 KNZ76262.1 - 0.0001 22.7 0.0 0.00098 19.6 0.0 2.4 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KNZ76262.1 - 0.00013 21.8 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KNZ76262.1 - 0.0016 17.7 0.0 0.0046 16.2 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_17 PF13207.1 KNZ76262.1 - 0.0037 18.0 0.1 0.0099 16.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 KNZ76262.1 - 0.0065 16.0 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KNZ76262.1 - 0.012 15.0 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 KNZ76262.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase MobB PF03205.9 KNZ76262.1 - 0.014 15.0 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KNZ76262.1 - 0.053 13.6 0.0 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 KNZ76262.1 - 0.061 12.3 0.2 0.083 11.9 0.2 1.2 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 KNZ76262.1 - 0.1 11.5 0.0 0.22 10.3 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 KNZ76262.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 KNZ76262.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain FAM74 PF15026.1 KNZ76263.1 - 0.041 13.5 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 FAM74 protein Arrestin_N PF00339.24 KNZ76264.1 - 4e-06 26.7 0.0 4.2e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KNZ76264.1 - 0.00015 21.3 0.0 0.0013 18.3 0.0 2.1 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_C PF02752.17 KNZ76264.1 - 0.0004 20.4 0.0 0.0052 16.8 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain HSF_DNA-bind PF00447.12 KNZ76265.1 - 1.4e-31 108.7 0.2 2.6e-31 107.8 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding DUF2780 PF11075.3 KNZ76265.1 - 0.074 13.1 0.1 0.074 13.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) PEP-utilisers_N PF05524.8 KNZ76266.1 - 0.064 13.0 0.8 0.29 10.9 0.5 2.1 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal AT_hook PF02178.14 KNZ76266.1 - 3.5 7.6 8.5 8.1 6.4 5.9 1.7 1 0 0 1 1 1 0 AT hook motif Cyclin PF08613.6 KNZ76267.1 - 2.5e-12 47.4 0.0 3.5e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KNZ76267.1 - 4.7e-12 45.5 0.0 6.8e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3608 PF12257.3 KNZ76268.1 - 1.1e-63 214.7 0.0 1.6e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KNZ76268.1 - 9.8e-20 70.0 0.1 2.2e-19 68.9 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Acetyltransf_1 PF00583.19 KNZ76269.1 - 1.8e-10 40.6 0.1 2.8e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KNZ76269.1 - 8.1e-06 25.5 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KNZ76269.1 - 0.0001 22.3 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KNZ76269.1 - 0.0039 17.0 0.4 0.0074 16.1 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNZ76269.1 - 0.033 14.2 0.0 0.046 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KNZ76269.1 - 0.042 13.8 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KNZ76269.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PAS_10 PF13596.1 KNZ76270.1 - 0.0021 18.3 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 PAS domain F-box PF00646.28 KNZ76271.1 - 0.011 15.4 0.5 0.033 13.8 0.3 1.9 1 0 0 1 1 1 0 F-box domain Peptidase_S28 PF05577.7 KNZ76274.1 - 1.8e-46 158.6 0.1 1.3e-38 132.6 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 KNZ76274.1 - 0.0057 16.5 0.1 0.013 15.4 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ76274.1 - 0.028 13.6 0.8 0.061 12.5 0.6 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family CRS1_YhbY PF01985.16 KNZ76274.1 - 0.2 11.6 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain UCH PF00443.24 KNZ76275.1 - 2.9e-43 147.9 0.0 4.5e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNZ76275.1 - 8.1e-06 25.4 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase p450 PF00067.17 KNZ76276.1 - 1.6e-40 139.0 0.0 3.5e-26 91.7 0.0 2.9 2 1 0 2 2 2 2 Cytochrome P450 zf-C2H2_jaz PF12171.3 KNZ76277.1 - 0.0084 16.2 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KNZ76277.1 - 0.081 13.0 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KNZ76277.1 - 0.09 13.0 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Cut8_N PF14482.1 KNZ76277.1 - 0.098 12.6 0.3 0.098 12.6 0.2 2.6 2 1 0 2 2 2 0 Cut8 proteasome-binding domain SPATIAL PF15256.1 KNZ76277.1 - 0.4 10.7 9.2 0.042 13.9 1.3 2.1 2 0 0 2 2 2 0 SPATIAL Rtf2 PF04641.7 KNZ76277.1 - 2.7 7.1 13.8 2.3 7.3 0.3 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger CAF-1_p150 PF11600.3 KNZ76277.1 - 3.2 7.0 35.2 0.88 8.8 14.7 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal APH PF01636.18 KNZ76278.1 - 3.7e-10 39.9 0.0 8.7e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.18 KNZ76279.1 - 1.8e-11 44.2 0.0 2.7e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KNZ76279.1 - 3e-05 22.8 0.0 0.038 12.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) DNA_pol_A_exo1 PF01612.15 KNZ76280.1 - 8.6e-06 25.3 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease RVP_2 PF08284.6 KNZ76281.1 - 0.0032 17.3 0.1 0.0035 17.2 0.1 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Allexi_40kDa PF05549.6 KNZ76282.1 - 0.0027 17.0 0.2 0.0033 16.7 0.1 1.1 1 0 0 1 1 1 1 Allexivirus 40kDa protein DUF4396 PF14342.1 KNZ76282.1 - 0.019 15.0 1.6 0.048 13.7 0.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) tRNA-synt_His PF13393.1 KNZ76282.1 - 0.11 11.5 0.7 0.13 11.2 0.5 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Phage_capsid PF05065.8 KNZ76282.1 - 0.16 11.1 1.2 0.19 10.9 0.8 1.1 1 0 0 1 1 1 0 Phage capsid family Mod_r PF07200.8 KNZ76283.1 - 0.018 14.9 1.8 0.018 14.9 1.2 1.7 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4164 PF13747.1 KNZ76283.1 - 0.021 14.9 1.1 0.021 14.9 0.7 2.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4164) WD40 PF00400.27 KNZ76284.1 - 2.9e-13 49.1 0.0 0.00019 21.1 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box PF00646.28 KNZ76284.1 - 1.1e-06 28.1 1.0 4e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KNZ76284.1 - 5.1e-06 26.1 3.2 2e-05 24.2 0.2 2.5 2 0 0 2 2 2 1 F-box-like IL11 PF07400.6 KNZ76288.1 - 0.45 10.0 8.1 0.12 11.9 3.0 1.9 1 1 1 2 2 2 0 Interleukin 11 p450 PF00067.17 KNZ76289.1 - 1.3e-56 192.1 0.0 1.1e-39 136.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 KNZ76290.1 - 1.9e-68 231.1 0.0 2.3e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 gag-asp_proteas PF13975.1 KNZ76291.1 - 0.00045 19.9 0.0 0.00058 19.6 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KNZ76291.1 - 0.00067 19.6 0.0 0.00067 19.6 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KNZ76291.1 - 0.0012 19.2 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease WD40 PF00400.27 KNZ76294.1 - 5.6e-10 38.7 0.4 3.1e-07 30.0 0.1 3.7 3 1 1 4 4 4 2 WD domain, G-beta repeat tRNA-synt_2c PF01411.14 KNZ76295.1 - 2.4e-25 88.8 0.4 4.6e-25 87.9 0.3 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KNZ76295.1 - 4.2e-16 58.5 0.0 1.5e-15 56.7 0.0 2.0 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Herpes_Helicase PF02689.9 KNZ76296.1 - 1.1e-05 23.4 0.0 1.2e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Helicase Usp PF00582.21 KNZ76299.1 - 2.3e-06 27.8 2.2 3.1e-05 24.1 1.6 2.0 1 1 0 1 1 1 1 Universal stress protein family ADPrib_exo_Tox PF03496.9 KNZ76299.1 - 0.053 12.7 0.0 0.096 11.8 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme Glyco_hydro_47 PF01532.15 KNZ76300.1 - 2.1e-29 102.4 0.0 5e-22 78.1 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Glyco_hydro_31 PF01055.21 KNZ76301.1 - 2.4e-21 76.0 0.2 5.6e-19 68.2 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KNZ76301.1 - 9.4e-14 51.0 0.2 1.7e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Galactose mutarotase-like SAGA-Tad1 PF12767.2 KNZ76302.1 - 0.0051 16.5 7.9 0.0072 16.0 5.5 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Draxin PF15550.1 KNZ76302.1 - 2.3 7.7 6.6 3.1 7.3 4.6 1.1 1 0 0 1 1 1 0 Draxin PIF1 PF05970.9 KNZ76303.1 - 1.3e-106 356.6 0.0 1.6e-106 356.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ76303.1 - 0.0019 17.8 0.0 0.0036 16.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KNZ76303.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KNZ76303.1 - 0.078 12.4 0.1 0.16 11.4 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MIP-T3 PF10243.4 KNZ76304.1 - 0.17 10.3 33.8 0.22 9.9 23.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 KNZ76304.1 - 3.9 5.2 26.4 4.6 5.0 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family Dor1 PF04124.7 KNZ76305.1 - 3.5e-43 147.3 0.0 1.8e-42 144.9 0.0 1.9 1 1 0 1 1 1 1 Dor1-like family Zw10 PF06248.8 KNZ76305.1 - 0.088 10.9 0.0 0.14 10.2 0.0 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Baculo_PEP_C PF04513.7 KNZ76305.1 - 0.094 12.5 0.4 0.58 9.9 0.4 2.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vps51 PF08700.6 KNZ76305.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Vps51/Vps67 Herpes_gE PF02480.11 KNZ76307.1 - 0.045 12.0 0.0 0.1 10.8 0.0 1.6 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E G-alpha PF00503.15 KNZ76308.1 - 3.3e-104 348.6 0.1 5.4e-91 305.1 0.0 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 KNZ76308.1 - 1.3e-11 44.0 1.7 3.3e-08 32.9 1.2 3.2 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 KNZ76308.1 - 0.0049 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KNZ76308.1 - 0.038 13.4 0.1 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 KNZ76308.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 KNZ76308.1 - 0.12 11.4 0.1 11 5.0 0.0 2.6 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Ribonuc_L-PSP PF01042.16 KNZ76309.1 - 1.3e-42 144.3 0.1 1.5e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Proteasome PF00227.21 KNZ76310.1 - 3.3e-56 189.5 0.0 4.1e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Inositol_P PF00459.20 KNZ76311.1 - 1.5e-66 224.4 0.0 1.7e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Sugar_tr PF00083.19 KNZ76312.1 - 1.5e-113 379.8 7.1 2.1e-113 379.2 4.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ76312.1 - 1e-17 63.9 27.9 8.8e-15 54.2 5.5 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily DASH_Ask1 PF08655.5 KNZ76314.1 - 2.6e-21 75.2 0.1 5.4e-21 74.1 0.1 1.6 1 0 0 1 1 1 1 DASH complex subunit Ask1 TIP49 PF06068.8 KNZ76315.1 - 1.8e-177 590.0 3.2 2.1e-177 589.8 2.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KNZ76315.1 - 1.3e-08 35.1 2.9 9.4e-06 25.8 0.0 3.4 3 1 1 4 4 4 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KNZ76315.1 - 8.8e-07 28.2 3.3 0.0052 15.8 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 KNZ76315.1 - 0.00016 20.6 0.2 0.00032 19.6 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 KNZ76315.1 - 0.00023 21.1 0.0 0.0018 18.2 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 KNZ76315.1 - 0.00034 20.0 0.3 0.00086 18.7 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KNZ76315.1 - 0.0008 19.5 0.6 0.21 11.7 0.0 2.9 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 KNZ76315.1 - 0.00099 18.3 1.5 0.026 13.7 0.3 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KNZ76315.1 - 0.0076 15.9 1.6 5.6 6.6 0.0 3.4 3 1 1 4 4 4 2 AAA domain (dynein-related subfamily) TFIID-31kDa PF02291.10 KNZ76315.1 - 0.012 15.4 0.4 0.024 14.3 0.3 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Zeta_toxin PF06414.7 KNZ76315.1 - 0.048 12.7 0.9 4.7 6.2 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Dynactin PF12455.3 KNZ76316.1 - 1.1e-83 280.3 1.8 1.1e-83 280.3 1.2 3.2 4 1 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 KNZ76316.1 - 1.3e-20 72.8 1.1 2.7e-20 71.8 0.5 1.7 2 0 0 2 2 2 1 CAP-Gly domain TMF_DNA_bd PF12329.3 KNZ76316.1 - 0.00077 19.2 4.9 0.00077 19.2 3.4 10.1 9 2 1 10 10 10 4 TATA element modulatory factor 1 DNA binding Strep_SA_rep PF06696.6 KNZ76316.1 - 0.98 9.2 19.9 0.22 11.3 5.0 2.9 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Raptor_N PF14538.1 KNZ76317.1 - 1.4e-63 213.3 0.0 5.4e-63 211.4 0.0 2.0 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KNZ76317.1 - 9.1e-14 50.7 7.9 2.1e-07 30.5 0.1 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat HEAT PF02985.17 KNZ76317.1 - 2.7e-05 23.8 1.1 0.0012 18.7 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 KNZ76317.1 - 4.4e-05 23.6 0.2 0.00063 19.9 0.0 2.6 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 KNZ76317.1 - 0.012 16.0 5.3 0.016 15.7 0.4 3.5 3 1 0 3 3 3 0 HEAT-like repeat Dus PF01207.12 KNZ76318.1 - 2.2e-51 174.5 0.1 3.8e-51 173.7 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) CPSase_L_D2 PF02786.12 KNZ76319.1 - 1e-70 237.2 0.0 1.6e-70 236.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KNZ76319.1 - 7.4e-44 148.3 0.2 2.6e-43 146.5 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KNZ76319.1 - 1.6e-31 108.4 0.0 1.5e-30 105.3 0.0 2.6 2 1 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KNZ76319.1 - 2e-16 59.3 1.9 4.4e-16 58.2 1.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KNZ76319.1 - 7.5e-14 51.1 0.0 1.7e-13 50.0 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 KNZ76319.1 - 2.4e-13 50.2 0.0 9.3e-13 48.3 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KNZ76319.1 - 1.9e-07 30.6 0.0 4.2e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KNZ76319.1 - 2e-07 30.4 0.0 6.9e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KNZ76319.1 - 2.7e-06 26.9 0.3 8.4e-06 25.3 0.1 1.9 1 1 1 2 2 2 1 Biotin-lipoyl like GARS_A PF01071.14 KNZ76319.1 - 0.0063 16.1 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 KNZ76319.1 - 0.0071 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.1 KNZ76319.1 - 0.008 15.8 0.5 0.24 11.1 0.2 2.8 3 0 0 3 3 3 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.1 KNZ76319.1 - 0.015 15.5 0.4 3.3 8.0 0.0 3.0 3 0 0 3 3 3 0 HlyD family secretion protein Toxin_59 PF15537.1 KNZ76319.1 - 0.024 14.7 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative toxin 59 HlyD PF00529.15 KNZ76319.1 - 0.11 11.7 1.4 2.8 7.1 0.0 2.2 1 1 1 2 2 2 0 HlyD family secretion protein NQRA PF05896.6 KNZ76319.1 - 0.12 11.5 0.2 0.21 10.7 0.2 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_2 PF12700.2 KNZ76319.1 - 0.14 11.2 0.5 0.68 9.0 0.1 1.9 1 1 1 2 2 2 0 HlyD family secretion protein PK_C PF02887.11 KNZ76319.1 - 2.5 7.6 5.4 34 4.0 0.0 3.1 3 1 0 3 3 2 0 Pyruvate kinase, alpha/beta domain CART PF06373.6 KNZ76321.1 - 0.0075 16.1 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 Cocaine and amphetamine regulated transcript protein (CART) DUF2413 PF10310.4 KNZ76321.1 - 0.14 10.9 1.4 0.16 10.7 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Adaptin_N PF01602.15 KNZ76323.1 - 4.6e-108 361.8 0.3 5.9e-108 361.4 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KNZ76323.1 - 7.9e-09 35.6 3.8 0.23 11.7 0.5 5.0 4 1 1 5 5 5 3 HEAT repeats Cnd1 PF12717.2 KNZ76323.1 - 4.3e-07 29.9 1.4 0.039 13.7 0.0 3.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KNZ76323.1 - 5e-06 26.1 4.4 2 8.7 0.0 6.4 7 0 0 7 7 7 2 HEAT repeat DUF2435 PF10363.4 KNZ76323.1 - 0.00054 19.8 1.2 0.56 10.1 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 KNZ76323.1 - 0.0077 16.6 4.8 2.6 8.6 0.0 5.9 6 1 2 8 8 8 1 HEAT-like repeat Arm PF00514.18 KNZ76323.1 - 0.019 14.7 0.2 42 4.1 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.3 KNZ76323.1 - 0.12 12.3 0.9 12 5.8 0.0 3.6 2 2 1 3 3 3 0 V-ATPase subunit H Nipped-B_C PF12830.2 KNZ76323.1 - 0.15 11.6 2.6 8.3 6.0 0.1 3.6 3 1 1 4 4 4 0 Sister chromatid cohesion C-terminus Pkinase PF00069.20 KNZ76324.1 - 4.5e-69 232.4 0.0 6.4e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ76324.1 - 4.2e-50 170.2 0.0 5.9e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ76324.1 - 8.8e-05 21.6 0.0 0.00052 19.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.6 KNZ76324.1 - 0.0075 15.5 0.6 0.012 14.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) ORC6 PF05460.8 KNZ76324.1 - 0.5 9.4 3.0 0.76 8.8 2.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF605 PF04652.11 KNZ76324.1 - 5.9 6.1 12.7 9.1 5.5 5.1 2.1 2 0 0 2 2 2 0 Vta1 like Cation_efflux PF01545.16 KNZ76325.1 - 4.8e-35 121.0 2.3 5.7e-35 120.7 1.6 1.1 1 0 0 1 1 1 1 Cation efflux family Transposase_23 PF03017.9 KNZ76325.1 - 0.053 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 TNP1/EN/SPM transposase FCP1_C PF09309.5 KNZ76326.1 - 0.093 12.0 6.7 0.016 14.5 2.0 1.6 1 1 0 1 1 1 0 FCP1, C-terminal CcmB PF03379.8 KNZ76327.1 - 0.0058 15.8 0.3 0.0078 15.4 0.2 1.2 1 0 0 1 1 1 1 CcmB protein Pkinase PF00069.20 KNZ76328.1 - 0.089 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pyridox_oxase_2 PF12766.2 KNZ76331.1 - 7.6e-23 80.7 0.0 1.4e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 KNZ76331.1 - 0.012 15.5 0.0 0.035 14.1 0.0 1.8 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Homeobox PF00046.24 KNZ76332.1 - 8e-18 63.8 2.4 1.3e-17 63.0 1.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KNZ76332.1 - 0.0053 16.4 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain GRAM PF02893.15 KNZ76333.1 - 6.7e-15 54.3 0.0 1.5e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Pyr_redox_3 PF13738.1 KNZ76334.1 - 1.5e-19 70.8 0.0 2.6e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ76334.1 - 8.2e-09 35.3 0.0 2.2e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KNZ76334.1 - 9.2e-07 27.4 0.1 0.0033 15.6 0.0 3.0 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 KNZ76334.1 - 4.3e-05 23.3 0.0 0.00042 20.1 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KNZ76334.1 - 0.0043 16.0 0.0 0.32 9.8 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KNZ76334.1 - 0.0064 16.3 0.0 0.44 10.4 0.0 2.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 KNZ76335.1 - 7.4e-62 208.8 0.0 1.8e-36 125.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ76335.1 - 1.9e-26 92.7 0.0 2.4e-15 56.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KNZ76335.1 - 0.0043 17.5 13.4 0.0045 17.4 5.7 3.9 2 1 0 2 2 2 1 Protein kinase C terminal domain PX PF00787.19 KNZ76335.1 - 0.0085 15.8 0.0 0.051 13.3 0.0 2.3 2 0 0 2 2 2 1 PX domain Kdo PF06293.9 KNZ76335.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ76335.1 - 0.059 13.0 0.3 0.74 9.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Hs1pro-1_C PF07014.7 KNZ76335.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus CorA PF01544.13 KNZ76336.1 - 3.2e-34 118.2 7.4 2.4e-29 102.3 4.6 2.7 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein RCC1 PF00415.13 KNZ76338.1 - 1.4e-22 79.5 17.1 5.4e-06 26.5 0.3 7.8 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KNZ76338.1 - 6.7e-13 47.8 23.9 0.00063 19.2 0.0 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat PfkB PF00294.19 KNZ76339.1 - 6.1e-67 225.8 1.7 7.5e-67 225.5 1.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MRP-L20 PF12824.2 KNZ76340.1 - 4.4 7.2 7.5 5 7.0 2.2 2.1 1 1 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 Calreticulin PF00262.13 KNZ76341.1 - 4e-153 509.4 11.8 5.7e-153 508.8 8.2 1.2 1 0 0 1 1 1 1 Calreticulin family GTP_EFTU PF00009.22 KNZ76341.1 - 5e-42 143.4 0.1 7.7e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KNZ76341.1 - 1.9e-26 91.9 0.0 5.3e-26 90.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KNZ76341.1 - 1.1e-20 73.2 0.0 3.1e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KNZ76341.1 - 4.5e-09 36.3 0.0 1.1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KNZ76341.1 - 5e-06 26.2 0.1 2.5e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KNZ76341.1 - 1.5e-05 24.8 0.1 3e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KNZ76341.1 - 6.1e-05 23.4 0.2 0.00012 22.5 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KNZ76341.1 - 0.005 16.0 0.1 0.018 14.2 0.1 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 KNZ76341.1 - 0.045 13.5 0.1 3.8 7.3 0.1 2.5 1 1 1 2 2 2 0 Dynamin family GBP PF02263.14 KNZ76341.1 - 0.33 9.9 0.0 0.61 9.0 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Prefoldin_2 PF01920.15 KNZ76342.1 - 3.1e-15 55.8 9.2 4.4e-15 55.3 6.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.2 KNZ76342.1 - 0.0078 16.0 1.0 0.0078 16.0 0.7 2.0 2 0 0 2 2 2 1 Tropomyosin like NPV_P10 PF05531.7 KNZ76342.1 - 0.096 12.9 0.6 0.096 12.9 0.4 2.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 KNZ76342.1 - 0.12 12.4 7.7 0.27 11.2 5.3 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain RasGAP_C PF03836.10 KNZ76342.1 - 0.36 10.4 5.2 0.14 11.8 0.3 2.1 2 0 0 2 2 2 0 RasGAP C-terminus Myosin_tail_1 PF01576.14 KNZ76342.1 - 1 6.9 9.5 0.03 12.0 1.3 1.8 2 0 0 2 2 2 0 Myosin tail TMF_DNA_bd PF12329.3 KNZ76342.1 - 1.4 8.7 12.1 0.063 13.0 4.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CorA PF01544.13 KNZ76342.1 - 2.8 6.8 7.8 2 7.3 1.3 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 KNZ76342.1 - 5.9 6.7 10.9 13 5.5 7.6 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.3 KNZ76342.1 - 8.7 5.5 10.7 2 7.5 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF3847 PF12958.2 KNZ76342.1 - 9.2 6.1 8.8 0.99 9.2 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) TPR_11 PF13414.1 KNZ76343.1 - 3.9e-12 45.6 5.9 2e-11 43.3 2.5 3.0 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 KNZ76343.1 - 2.6e-05 23.7 6.8 0.00021 20.9 1.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ76343.1 - 0.0043 17.5 0.4 0.032 14.8 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ76343.1 - 0.0086 16.7 3.5 0.021 15.5 1.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ76343.1 - 0.0094 15.5 3.0 0.0094 15.5 2.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ76343.1 - 0.011 15.8 2.6 0.52 10.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC2_membrane PF01061.19 KNZ76344.1 - 6.6e-52 175.7 49.9 1.6e-37 128.7 19.0 4.1 5 0 0 5 5 5 2 ABC-2 type transporter ABC_tran PF00005.22 KNZ76344.1 - 5.2e-32 111.0 0.1 5.7e-15 55.8 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 KNZ76344.1 - 1.1e-19 70.0 2.5 1.5e-15 56.6 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter AAA_22 PF13401.1 KNZ76344.1 - 2e-06 27.9 0.2 0.13 12.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KNZ76344.1 - 6.3e-06 25.7 0.3 0.066 12.6 0.1 3.0 3 0 0 3 3 3 2 AAA domain cobW PF02492.14 KNZ76344.1 - 1.3e-05 24.7 0.0 0.016 14.6 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KNZ76344.1 - 0.00013 21.9 0.2 0.13 12.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KNZ76344.1 - 0.0019 18.9 0.1 0.31 11.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KNZ76344.1 - 0.002 18.0 2.6 0.23 11.4 0.1 3.0 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 KNZ76344.1 - 0.0042 16.5 0.6 0.04 13.4 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KNZ76344.1 - 0.0084 15.3 0.0 0.026 13.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 KNZ76344.1 - 0.0087 15.3 0.0 0.13 11.4 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 KNZ76344.1 - 0.01 15.2 0.1 0.27 10.6 0.0 2.7 2 1 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 KNZ76344.1 - 0.013 15.8 0.1 0.95 9.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KNZ76344.1 - 0.015 14.7 0.1 6.2 6.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 KNZ76344.1 - 0.023 14.3 0.6 3.5 7.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 KNZ76344.1 - 0.045 13.7 7.6 0.44 10.5 0.4 3.8 4 1 0 4 4 4 0 AAA ATPase domain AAA_19 PF13245.1 KNZ76344.1 - 0.049 13.3 3.2 1.3 8.7 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 KNZ76344.1 - 0.15 12.2 0.4 34 4.6 0.0 3.0 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KNZ76344.1 - 0.38 10.2 5.0 5.6 6.4 0.1 3.1 3 1 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.12 KNZ76344.1 - 4 6.8 4.8 65 2.9 0.0 3.5 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein Glyco_hydro_cc PF11790.3 KNZ76345.1 - 1.4e-58 198.1 3.0 1.9e-58 197.7 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EF-hand_6 PF13405.1 KNZ76346.1 - 1.3e-07 30.9 0.3 0.0056 16.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KNZ76346.1 - 1.8e-06 27.0 0.1 8.8e-05 21.6 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KNZ76346.1 - 1.8e-06 27.9 1.6 3.9e-06 26.8 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KNZ76346.1 - 0.00047 19.2 0.2 0.018 14.3 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KNZ76346.1 - 0.017 14.7 0.2 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair DUF605 PF04652.11 KNZ76346.1 - 0.14 11.5 5.8 0.15 11.4 4.0 1.1 1 0 0 1 1 1 0 Vta1 like Dopey_N PF04118.9 KNZ76347.1 - 4.8e-111 370.4 0.1 1.3e-110 369.0 0.1 1.7 1 0 0 1 1 1 1 Dopey, N-terminal Mycobact_memb PF05423.8 KNZ76347.1 - 0.45 10.2 2.8 0.68 9.6 0.1 2.5 3 0 0 3 3 3 0 Mycobacterium membrane protein PBP1_TM PF14812.1 KNZ76349.1 - 0.0065 16.7 1.9 0.0065 16.7 1.3 2.5 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal SLX9 PF15341.1 KNZ76349.1 - 0.018 15.4 5.9 0.034 14.5 1.1 2.5 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 GFA PF04828.9 KNZ76350.1 - 7e-15 54.7 2.0 1.1e-14 54.0 1.4 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Terminase_GpA PF05876.7 KNZ76350.1 - 0.24 9.7 2.1 0.29 9.4 1.5 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Sgf11 PF08209.6 KNZ76350.1 - 7.2 6.0 11.1 6.5 6.1 0.6 3.5 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) ATP-synt_E PF05680.7 KNZ76351.1 - 1.1e-17 63.7 0.3 1.1e-17 63.7 0.2 1.6 2 0 0 2 2 2 1 ATP synthase E chain HeLo PF14479.1 KNZ76351.1 - 0.0063 16.2 0.2 0.008 15.9 0.1 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation LdpA_C PF12617.3 KNZ76351.1 - 0.08 12.1 0.0 0.092 12.0 0.0 1.1 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal Aldo_ket_red PF00248.16 KNZ76351.1 - 0.099 11.4 0.0 0.12 11.1 0.0 1.0 1 0 0 1 1 1 0 Aldo/keto reductase family WD40 PF00400.27 KNZ76352.1 - 4.2e-34 115.2 11.0 2.2e-09 36.8 0.5 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KNZ76352.1 - 2.5e-30 104.2 0.7 5.4e-30 103.1 0.5 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex RAMP4 PF06624.7 KNZ76353.1 - 1.2e-08 34.2 0.1 1.7e-08 33.8 0.1 1.3 1 1 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF2431 PF10354.4 KNZ76354.1 - 6.3e-40 136.8 0.0 2.8e-39 134.7 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) PBP1_TM PF14812.1 KNZ76354.1 - 2.1 8.6 5.5 0.3 11.4 0.4 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cut8_N PF14482.1 KNZ76354.1 - 2.5 8.1 5.7 0.33 10.9 0.1 2.3 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Fip1 PF05182.8 KNZ76356.1 - 1.5e-20 72.1 0.6 2.5e-20 71.4 0.4 1.4 1 0 0 1 1 1 1 Fip1 motif DUF3189 PF11385.3 KNZ76356.1 - 0.065 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) ING PF12998.2 KNZ76357.1 - 5.7e-13 49.0 0.7 9e-13 48.4 0.5 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KNZ76357.1 - 2.8e-09 36.5 6.3 4.7e-09 35.7 4.3 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KNZ76357.1 - 0.28 10.5 1.9 0.51 9.6 1.3 1.4 1 0 0 1 1 1 0 PHD-finger Vert_IL3-reg_TF PF06529.6 KNZ76359.1 - 0.091 11.7 0.1 0.18 10.7 0.1 1.4 1 0 0 1 1 1 0 Vertebrate interleukin-3 regulated transcription factor RNase_H PF00075.19 KNZ76361.1 - 1.8e-24 86.5 0.0 3.4e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 KNZ76361.1 - 6.5e-17 61.2 0.5 1.3e-16 60.3 0.3 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin NIF PF03031.13 KNZ76362.1 - 7.5e-25 87.4 0.0 8.6e-22 77.5 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KNZ76362.1 - 3.1e-10 39.7 0.1 5.4e-09 35.7 0.0 2.5 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 KNZ76362.1 - 1.9e-05 24.6 0.0 0.0001 22.3 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain FA_desaturase PF00487.19 KNZ76362.1 - 0.17 11.2 0.3 0.29 10.5 0.2 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF837 PF05769.6 KNZ76363.1 - 7.5e-08 32.1 10.3 0.00012 21.6 4.1 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF837) DUF3869 PF12985.2 KNZ76363.1 - 0.011 16.1 0.1 0.018 15.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3869) Mito_fiss_reg PF05308.6 KNZ76363.1 - 1.2 8.4 9.7 3.1 7.0 6.7 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator NYD-SP28_assoc PF14775.1 KNZ76363.1 - 1.7 8.4 9.3 3.5 7.4 0.3 3.0 3 0 0 3 3 3 0 Sperm tail C-terminal domain CAP_N PF01213.14 KNZ76363.1 - 2.9 7.0 7.2 5.4 6.1 5.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Rad50_zn_hook PF04423.9 KNZ76368.1 - 0.027 13.9 0.4 0.083 12.3 0.2 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif SLT_L PF14718.1 KNZ76368.1 - 0.047 13.4 1.9 0.1 12.4 1.3 1.5 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain APH PF01636.18 KNZ76369.1 - 1.9e-13 50.7 0.0 2.5e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KNZ76369.1 - 0.00013 21.2 0.0 0.0014 17.8 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 KNZ76369.1 - 0.00026 19.7 0.0 0.00039 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 KNZ76369.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase SNF2_N PF00176.18 KNZ76370.1 - 5.9e-66 222.2 0.0 8.7e-66 221.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KNZ76370.1 - 3.9e-15 55.6 0.0 2.8e-14 52.9 0.0 2.4 2 0 0 2 2 2 1 HIRAN domain Helicase_C PF00271.26 KNZ76370.1 - 9.2e-11 41.4 0.0 2.2e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KNZ76370.1 - 3.8e-08 33.0 0.0 7.8e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KNZ76370.1 - 2e-06 27.7 0.0 4.7e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 KNZ76370.1 - 2.2e-06 27.2 15.7 4.3e-06 26.2 10.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ76370.1 - 2.4e-06 27.4 15.8 5.3e-06 26.3 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ76370.1 - 2.9e-05 23.7 16.8 3.4e-05 23.5 10.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 KNZ76370.1 - 0.00014 21.6 14.5 0.0003 20.6 10.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KNZ76370.1 - 0.00075 19.1 13.2 0.0014 18.2 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 KNZ76370.1 - 0.017 15.0 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-RING_5 PF14634.1 KNZ76370.1 - 0.023 14.3 13.5 0.045 13.4 9.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.3 KNZ76370.1 - 0.078 12.5 8.4 0.19 11.2 5.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 KNZ76370.1 - 0.15 11.6 11.3 0.28 10.7 7.8 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Cpn60_TCP1 PF00118.19 KNZ76371.1 - 1e-143 479.4 0.6 1.2e-143 479.2 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Bot1p PF12298.3 KNZ76372.1 - 4.1e-29 101.7 0.4 4.1e-29 101.7 0.3 2.1 3 0 0 3 3 3 1 Eukaryotic mitochondrial regulator protein Methyltransf_16 PF10294.4 KNZ76373.1 - 5.7e-15 55.1 0.1 1.3e-14 54.0 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KNZ76373.1 - 0.0021 17.4 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KNZ76373.1 - 0.037 14.6 0.0 0.061 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KNZ76373.1 - 0.068 12.6 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) WLM PF08325.5 KNZ76374.1 - 3.9e-50 170.3 0.0 5.3e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 KNZ76374.1 - 0.0007 19.4 0.1 0.0014 18.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 KNZ76374.1 - 0.029 14.0 0.1 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_MA_2 PF13485.1 KNZ76374.1 - 0.067 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily DUF955 PF06114.8 KNZ76374.1 - 0.073 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF955) Methyltransf_11 PF08241.7 KNZ76375.1 - 1.3e-11 44.8 0.0 3.1e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ76375.1 - 3.6e-10 39.6 0.0 6.7e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ76375.1 - 2.1e-09 37.3 0.0 3.9e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ76375.1 - 2.1e-08 34.4 0.0 4.2e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ76375.1 - 2.5e-08 34.4 0.0 5.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ76375.1 - 2.5e-05 24.6 0.0 6.4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ76375.1 - 0.00011 22.2 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KNZ76375.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KNZ76375.1 - 0.023 13.7 0.0 0.05 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 KNZ76375.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KNZ76375.1 - 0.2 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SF3b10 PF07189.6 KNZ76376.1 - 2.6e-25 88.0 0.0 3.3e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Sas10_Utp3 PF04000.10 KNZ76377.1 - 1.5e-16 60.3 0.0 3.4e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family IpaB_EvcA PF03278.8 KNZ76377.1 - 0.0077 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 IpaB/EvcA family F-box-like PF12937.2 KNZ76378.1 - 2.4e-05 23.9 0.1 0.00012 21.7 0.1 2.2 1 1 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KNZ76378.1 - 0.0018 18.1 9.2 2.6 8.3 0.1 7.8 6 1 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.28 KNZ76378.1 - 0.033 14.1 13.5 3.9 7.8 0.2 7.3 7 1 0 7 7 7 0 Leucine Rich Repeat Sec1 PF00995.18 KNZ76379.1 - 6.1e-114 381.6 0.0 8.1e-114 381.2 0.0 1.2 1 0 0 1 1 1 1 Sec1 family cNMP_binding PF00027.24 KNZ76379.1 - 1.4e-41 140.2 0.0 1.5e-18 66.4 0.0 4.6 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 KNZ76379.1 - 5.2e-17 62.4 5.3 1e-10 41.8 2.7 2.8 2 0 0 2 2 2 2 Patatin-like phospholipase ICL PF00463.16 KNZ76380.1 - 2.7e-196 652.8 0.2 3.1e-196 652.6 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KNZ76380.1 - 1.4e-12 47.3 0.2 6.8e-11 41.8 0.0 2.7 3 0 0 3 3 3 1 Phosphoenolpyruvate phosphomutase DUF2404 PF10296.4 KNZ76381.1 - 2.3e-28 98.1 0.0 5.2e-28 97.0 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH_9 PF15410.1 KNZ76381.1 - 0.058 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Fes1 PF08609.5 KNZ76382.1 - 4.4e-24 84.7 0.7 6.5e-23 81.0 0.2 2.8 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 KNZ76382.1 - 0.00013 22.2 1.5 0.072 13.3 0.2 3.0 1 1 2 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 KNZ76382.1 - 0.0034 17.8 0.0 5 7.7 0.0 3.7 3 1 1 4 4 4 1 HEAT-like repeat HEAT PF02985.17 KNZ76382.1 - 0.014 15.3 0.2 3.9 7.8 0.0 4.0 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.2 KNZ76382.1 - 0.091 12.6 0.1 0.28 11.0 0.0 1.8 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Exo5 PF09810.4 KNZ76384.1 - 6.2e-62 209.6 0.0 1.3e-60 205.3 0.0 2.1 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 KNZ76384.1 - 1.6e-05 24.4 0.1 0.00057 19.3 0.1 2.6 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily IncA PF04156.9 KNZ76385.1 - 0.0019 17.8 22.1 0.0019 17.8 15.3 7.1 1 1 6 7 7 7 4 IncA protein LPP PF04728.8 KNZ76385.1 - 0.02 14.6 4.5 2.2 8.1 0.0 4.6 5 0 0 5 5 5 0 Lipoprotein leucine-zipper Yae1_N PF09811.4 KNZ76386.1 - 1.1e-10 40.8 6.5 1.8e-10 40.1 4.5 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal BTB_2 PF02214.17 KNZ76388.1 - 0.00019 21.5 0.0 0.0017 18.4 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain WD40 PF00400.27 KNZ76389.1 - 3.4e-48 159.8 17.6 8.3e-09 35.0 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KNZ76389.1 - 0.00032 20.4 0.0 0.13 11.9 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A UBN2_2 PF14227.1 KNZ76390.1 - 0.0021 17.6 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ76390.1 - 0.0099 15.6 0.0 0.027 14.2 0.0 1.8 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type AFG1_ATPase PF03969.11 KNZ76392.1 - 3.5e-17 62.2 0.0 4.2e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 AFG1-like ATPase DUF269 PF03270.8 KNZ76392.1 - 0.025 14.5 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF269 Grp1_Fun34_YaaH PF01184.14 KNZ76395.1 - 9e-23 80.6 5.3 1.1e-22 80.3 3.7 1.2 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family Grp1_Fun34_YaaH PF01184.14 KNZ76396.1 - 5e-55 186.0 17.4 5.8e-55 185.8 12.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family p450 PF00067.17 KNZ76397.1 - 4.5e-28 97.9 0.0 6.1e-28 97.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF1201 PF06716.6 KNZ76397.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) VSP PF03302.8 KNZ76398.1 - 0.039 12.5 0.2 0.059 11.9 0.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein TPR_10 PF13374.1 KNZ76399.1 - 1.4e-23 82.0 0.3 1.7e-06 27.7 0.0 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ76399.1 - 5.3e-20 71.1 1.1 2e-12 46.8 0.2 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ76399.1 - 1.8e-07 31.6 0.3 0.0075 16.9 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ76399.1 - 1.2e-06 27.8 3.4 0.089 12.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ76399.1 - 1.2e-06 28.0 0.7 0.0014 18.2 0.3 2.6 1 1 1 2 2 2 2 TPR repeat DUF4404 PF14357.1 KNZ76399.1 - 0.00016 22.0 1.2 0.0045 17.3 0.3 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4404) TPR_2 PF07719.12 KNZ76399.1 - 0.00021 20.9 1.6 4.7 7.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ76399.1 - 0.00054 19.4 1.0 4.1 7.1 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ76399.1 - 0.001 19.0 0.1 0.43 10.8 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat C_GCAxxG_C_C PF09719.5 KNZ76399.1 - 0.0046 16.7 0.0 0.85 9.4 0.0 2.1 2 0 0 2 2 2 1 Putative redox-active protein (C_GCAxxG_C_C) TPR_14 PF13428.1 KNZ76399.1 - 0.0057 17.1 5.1 4.1 8.2 0.3 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat Hypoth_Ymh PF09509.5 KNZ76399.1 - 0.024 14.2 0.3 0.29 10.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (Hypoth_ymh) NUC173 PF08161.7 KNZ76399.1 - 0.029 13.7 0.3 0.23 10.7 0.1 1.9 1 1 1 2 2 2 0 NUC173 domain Eno-Rase_FAD_bd PF07055.7 KNZ76399.1 - 0.048 13.6 0.0 1.3 9.0 0.0 2.2 1 1 1 2 2 2 0 Enoyl reductase FAD binding domain YbaB_DNA_bd PF02575.11 KNZ76399.1 - 0.068 13.0 4.0 0.51 10.2 0.1 2.5 2 1 1 3 3 3 0 YbaB/EbfC DNA-binding family TPR_19 PF14559.1 KNZ76399.1 - 0.12 12.6 3.8 1.4 9.2 0.4 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF294_C PF10335.4 KNZ76399.1 - 0.15 11.6 1.7 3.1 7.4 0.3 2.3 2 1 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain Epimerase_2 PF02350.14 KNZ76402.1 - 9.9e-37 126.4 0.3 2.2e-36 125.3 0.2 1.4 1 1 1 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase Herpes_Helicase PF02689.9 KNZ76403.1 - 7e-08 30.7 0.0 7.4e-08 30.6 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ76403.1 - 0.011 15.8 0.0 0.018 15.2 0.0 1.4 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Asp_protease_2 PF13650.1 KNZ76405.1 - 0.0017 18.7 0.0 0.004 17.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KNZ76405.1 - 0.052 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease NSP10 PF09401.5 KNZ76405.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA synthesis protein NSP10 Chromo PF00385.19 KNZ76407.1 - 3.1e-16 58.7 0.2 3.7e-16 58.5 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KNZ76407.1 - 0.029 14.0 0.8 0.035 13.7 0.6 1.2 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Mtf2_C PF14061.1 KNZ76407.1 - 0.047 13.5 0.1 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 TPR_10 PF13374.1 KNZ76408.1 - 1.9e-99 323.1 13.3 8.7e-08 31.8 0.0 12.5 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ76408.1 - 6e-95 311.2 17.7 5e-17 61.5 0.3 7.3 5 1 2 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ76408.1 - 4.2e-33 113.2 23.1 6.7e-06 26.6 0.7 7.2 3 1 5 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ76408.1 - 7.6e-30 100.6 0.1 1.8 8.9 0.0 12.3 12 0 0 12 12 11 7 Tetratricopeptide repeat DUF4404 PF14357.1 KNZ76408.1 - 9e-26 90.1 18.0 0.44 11.0 0.0 11.7 2 1 10 12 12 11 8 Domain of unknown function (DUF4404) TPR_4 PF07721.9 KNZ76408.1 - 6.1e-22 75.7 28.5 1 9.9 0.0 11.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ76408.1 - 1.3e-17 63.1 16.0 0.0054 16.3 0.0 6.8 2 1 5 8 8 8 8 TPR repeat TPR_2 PF07719.12 KNZ76408.1 - 2.8e-16 58.0 48.0 0.44 10.5 0.2 12.0 12 0 0 12 12 11 8 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ76408.1 - 4.3e-13 48.0 26.5 2.5 8.0 0.1 11.6 11 0 0 11 11 11 1 Tetratricopeptide repeat NB-ARC PF00931.17 KNZ76408.1 - 8.3e-11 41.2 0.0 1.9e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.23 KNZ76408.1 - 2.7e-10 39.4 27.8 5.4 6.7 0.1 11.9 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ76408.1 - 2.7e-10 39.2 31.2 2.6 8.0 0.1 11.4 11 0 0 11 11 11 2 Tetratricopeptide repeat DUF3510 PF12022.3 KNZ76408.1 - 1.4e-06 28.4 0.6 0.99 9.5 0.1 5.3 2 1 2 4 4 4 2 Domain of unknown function (DUF3510) AAA_22 PF13401.1 KNZ76408.1 - 0.00012 22.2 0.0 0.0019 18.3 0.0 3.1 2 0 0 2 2 2 1 AAA domain PTR PF12789.2 KNZ76408.1 - 0.0021 17.8 0.4 27 4.7 0.0 5.5 8 0 0 8 8 5 0 Phage tail repeat like PPR PF01535.15 KNZ76408.1 - 0.0026 17.6 11.5 1.3e+02 2.8 0.0 9.4 11 0 0 11 11 11 0 PPR repeat Patatin PF01734.17 KNZ76408.1 - 0.036 14.0 0.4 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Patatin-like phospholipase Sec7 PF01369.15 KNZ76408.1 - 0.045 13.4 1.3 4.2 7.0 0.2 4.5 3 1 1 4 4 4 0 Sec7 domain AAA_5 PF07728.9 KNZ76408.1 - 0.053 13.2 0.0 0.39 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3887 PF13026.1 KNZ76408.1 - 0.068 13.4 6.2 58 4.0 0.1 6.5 5 3 3 9 9 7 0 Protein of unknown function (DUF3887) PTS_EIIA_2 PF00359.17 KNZ76408.1 - 0.2 11.3 2.3 14 5.3 0.2 4.2 3 1 1 4 4 4 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 GLTP PF08718.6 KNZ76408.1 - 0.28 11.2 3.8 87 3.1 0.1 4.4 4 0 0 4 4 4 0 Glycolipid transfer protein (GLTP) DUF3560 PF12083.3 KNZ76408.1 - 1.4 8.9 20.4 6.2 6.8 0.4 6.1 3 2 5 8 8 8 0 Domain of unknown function (DUF3560) TPR_14 PF13428.1 KNZ76408.1 - 3.8 8.4 47.4 40 5.2 0.2 11.2 9 2 2 11 11 11 0 Tetratricopeptide repeat Adeno_E3A PF05248.7 KNZ76410.1 - 0.068 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3A Tim17 PF02466.14 KNZ76411.1 - 0.12 12.4 0.2 0.12 12.4 0.1 2.9 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Mob1_phocein PF03637.12 KNZ76413.1 - 0.041 13.5 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Mob1/phocein family TFIID-18kDa PF02269.11 KNZ76417.1 - 4.2e-32 109.8 0.1 8.8e-32 108.7 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Asp_protease PF09668.5 KNZ76418.1 - 9.2e-60 199.6 0.1 2.6e-59 198.2 0.1 1.7 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.1 KNZ76418.1 - 3.9e-11 43.3 0.0 1.2e-10 41.6 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 KNZ76418.1 - 5.8e-08 32.4 0.6 1.8e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KNZ76418.1 - 4.1e-07 30.0 0.0 8.9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.26 KNZ76418.1 - 8.4e-06 25.4 0.9 2.7e-05 23.8 0.0 2.4 3 0 0 3 3 3 1 UBA/TS-N domain ubiquitin PF00240.18 KNZ76418.1 - 7.7e-05 22.0 0.0 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.6 KNZ76418.1 - 0.00026 20.3 4.5 0.00068 19.0 2.0 2.3 2 0 0 2 2 2 1 XPC-binding domain RVP PF00077.15 KNZ76418.1 - 0.0003 20.6 0.0 0.00081 19.2 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 KNZ76418.1 - 0.036 13.5 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain BASP1 PF05466.7 KNZ76418.1 - 1.6 8.5 7.7 3.3 7.4 5.4 1.4 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) UPF0029 PF01205.14 KNZ76420.1 - 2.9e-27 94.5 0.0 4.9e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KNZ76420.1 - 1.1e-06 28.5 0.4 2.1e-06 27.6 0.3 1.4 1 0 0 1 1 1 1 RWD domain Aldedh PF00171.17 KNZ76421.1 - 6.9e-161 535.6 0.2 7.7e-161 535.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAA_hydrolase PF01557.13 KNZ76422.1 - 2.9e-32 111.8 0.0 4e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family CDC14 PF08045.6 KNZ76423.1 - 5.3e-32 110.9 0.0 1.5e-26 93.1 0.0 2.2 2 0 0 2 2 2 2 Cell division control protein 14, SIN component KIF1B PF12423.3 KNZ76423.1 - 0.024 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinesin protein 1B HisKA_3 PF07730.8 KNZ76423.1 - 0.041 14.2 2.0 0.18 12.1 0.1 2.9 3 0 0 3 3 3 0 Histidine kinase PRCC PF10253.4 KNZ76423.1 - 1.7 9.3 12.7 0.056 14.1 4.3 1.8 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Coiled-coil_56 PF09813.4 KNZ76424.1 - 3.3e-09 36.6 0.0 5.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DASH_Spc19 PF08287.6 KNZ76426.1 - 4.7e-06 26.2 1.7 0.00074 19.1 0.0 2.2 1 1 1 2 2 2 2 Spc19 CASP_C PF08172.7 KNZ76426.1 - 0.016 14.2 0.2 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 CASP C terminal DUF4140 PF13600.1 KNZ76426.1 - 0.047 14.1 0.1 0.062 13.7 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) NuA4 PF09340.5 KNZ76426.1 - 0.093 12.3 1.3 0.14 11.7 0.9 1.3 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 VWA_2 PF13519.1 KNZ76427.1 - 1.1e-06 28.8 0.1 3e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KNZ76427.1 - 1.7e-06 28.0 0.0 2.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 KNZ76427.1 - 0.001 18.8 0.1 0.085 12.5 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.1 KNZ76427.1 - 0.044 13.4 0.1 0.88 9.2 0.0 2.6 2 1 0 2 2 2 0 von Willebrand factor type A domain Spc97_Spc98 PF04130.8 KNZ76428.1 - 4.1e-62 210.2 0.0 6.9e-62 209.4 0.0 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family Ribosomal_L1 PF00687.16 KNZ76429.1 - 1e-48 165.6 1.6 1.3e-48 165.2 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Mgm101p PF06420.7 KNZ76430.1 - 2e-73 245.3 0.2 5.2e-73 243.9 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial genome maintenance MGM101 MoCF_biosynth PF00994.19 KNZ76431.1 - 1.2e-58 196.5 0.1 3.1e-29 101.2 0.0 2.6 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KNZ76431.1 - 2.1e-28 98.6 0.1 3.3e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KNZ76431.1 - 8.1e-15 54.5 0.3 2.1e-14 53.2 0.1 1.9 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) PrpR_N PF06506.6 KNZ76431.1 - 0.12 11.7 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Propionate catabolism activator DUF498 PF04430.9 KNZ76432.1 - 8.8e-30 102.4 0.0 1.2e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) CHCH PF06747.8 KNZ76434.1 - 0.00069 19.4 6.6 0.00069 19.4 4.5 2.4 2 0 0 2 2 2 2 CHCH domain Pet191_N PF10203.4 KNZ76434.1 - 3.1 7.9 11.7 2 8.5 5.1 2.6 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 KNZ76434.1 - 8.9 6.1 15.7 7.8 6.3 3.4 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-MYND PF01753.13 KNZ76435.1 - 5.8e-10 38.8 10.8 1.1e-09 37.9 7.5 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KNZ76435.1 - 0.00043 19.8 7.2 0.0008 18.9 5.0 1.5 1 0 0 1 1 1 1 HIT zinc finger CNH PF00780.17 KNZ76436.1 - 1.2e-05 24.8 0.0 0.00053 19.4 0.0 2.2 2 0 0 2 2 2 2 CNH domain TRP PF06011.7 KNZ76437.1 - 8.2e-42 143.2 22.7 6.9e-32 110.5 3.8 2.6 2 1 0 2 2 2 2 Transient receptor potential (TRP) ion channel GatB_N PF02934.10 KNZ76438.1 - 1.3e-104 349.1 0.0 1.7e-104 348.7 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KNZ76438.1 - 1.8e-27 95.8 0.4 1.2e-26 93.2 0.3 2.1 1 1 0 1 1 1 1 GatB domain DeoC PF01791.4 KNZ76440.1 - 0.055 12.7 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 DeoC/LacD family aldolase Myb_CC_LHEQLE PF14379.1 KNZ76444.1 - 0.15 11.7 0.3 0.31 10.6 0.2 1.5 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif PAP_central PF04928.12 KNZ76445.1 - 6.2e-98 326.6 0.0 8.5e-98 326.1 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KNZ76445.1 - 5e-44 149.5 0.0 8e-44 148.9 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KNZ76445.1 - 2e-09 37.6 0.0 5.5e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 KNZ76445.1 - 0.076 10.5 0.0 0.14 9.6 0.0 1.3 1 0 0 1 1 1 0 Nrap protein Beta_helix PF13229.1 KNZ76446.1 - 1.2e-06 28.3 26.4 4.8e-05 23.1 18.3 2.8 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 KNZ76446.1 - 0.0013 17.9 12.4 0.0036 16.4 3.3 2.3 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Disaggr_assoc PF08480.5 KNZ76446.1 - 1.2 8.5 12.0 6.9 6.0 4.7 3.1 1 1 2 3 3 3 0 Disaggregatase related Rhomboid PF01694.17 KNZ76449.1 - 3e-07 30.5 6.4 4.5e-07 30.0 4.4 1.3 1 0 0 1 1 1 1 Rhomboid family CUE PF02845.11 KNZ76449.1 - 4.3e-07 29.2 0.2 7.1e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 CUE domain DER1 PF04511.10 KNZ76449.1 - 9.5e-05 21.9 6.2 0.00013 21.5 4.3 1.1 1 0 0 1 1 1 1 Der1-like family DUF1751 PF08551.5 KNZ76449.1 - 0.0039 17.5 0.2 0.0087 16.3 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) UBA PF00627.26 KNZ76449.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 UBA/TS-N domain eIF-3_zeta PF05091.7 KNZ76450.1 - 6.8e-185 615.5 0.0 8.5e-185 615.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RRM_1 PF00076.17 KNZ76451.1 - 9.9e-20 69.9 0.0 1.8e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ76451.1 - 1.6e-11 44.0 0.0 3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ76451.1 - 1.3e-08 34.5 0.0 2.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3464 PF11947.3 KNZ76451.1 - 0.011 15.2 0.7 0.011 15.2 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) DUF4642 PF15484.1 KNZ76451.1 - 0.021 14.7 4.0 0.034 14.1 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) SOBP PF15279.1 KNZ76451.1 - 0.031 14.6 1.6 0.039 14.3 1.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein TAF1D PF15333.1 KNZ76451.1 - 0.037 13.8 7.3 0.056 13.2 5.1 1.2 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D NARP1 PF12569.3 KNZ76451.1 - 0.075 11.7 5.6 0.093 11.4 3.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sec62 PF03839.11 KNZ76451.1 - 0.088 12.2 1.6 0.15 11.4 1.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Herpes_DNAp_acc PF04929.7 KNZ76451.1 - 0.93 8.3 7.5 1.2 8.0 5.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Protocadherin PF08374.6 KNZ76451.1 - 3 7.4 8.4 6.1 6.4 5.8 1.4 1 0 0 1 1 1 0 Protocadherin Nop14 PF04147.7 KNZ76452.1 - 2.4e-232 773.4 43.7 1.7e-125 420.0 0.1 2.0 1 1 1 2 2 2 2 Nop14-like family Utp12 PF04003.7 KNZ76452.1 - 0.033 14.0 0.2 0.65 9.9 0.0 2.6 2 0 0 2 2 2 0 Dip2/Utp12 Family PI3_PI4_kinase PF00454.22 KNZ76453.1 - 5e-50 170.1 0.0 1.4e-49 168.7 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KNZ76453.1 - 5.5e-34 117.6 1.5 1.6e-33 116.1 0.1 2.3 2 0 0 2 2 2 1 FAT domain UME PF08064.8 KNZ76453.1 - 1.3e-20 73.3 0.1 1.9e-18 66.3 0.0 4.0 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.15 KNZ76453.1 - 3.8e-12 45.4 0.1 1e-11 44.0 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 KNZ76453.1 - 0.019 14.9 0.4 2.4 8.4 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat Radial_spoke PF04712.7 KNZ76453.1 - 0.021 13.5 0.1 0.046 12.4 0.1 1.5 1 0 0 1 1 1 0 Radial spokehead-like protein TPR_19 PF14559.1 KNZ76453.1 - 0.024 14.9 0.1 1.2 9.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Rep_fac_C PF08542.6 KNZ76453.1 - 0.041 13.8 0.1 0.32 10.9 0.0 2.7 2 0 0 2 2 2 0 Replication factor C C-terminal domain Bunya_G1 PF03557.10 KNZ76453.1 - 1.1 6.9 0.1 1.7 6.3 0.1 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 YEATS PF03366.11 KNZ76454.1 - 2.5e-33 113.6 0.1 4.6e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 YEATS family DUF2695 PF10905.3 KNZ76454.1 - 0.16 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Dscam_C PF12355.3 KNZ76455.1 - 0.26 11.5 3.4 0.27 11.5 0.1 2.2 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Thioredoxin_4 PF13462.1 KNZ76456.1 - 1.2e-06 28.6 0.0 1.9e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin DIOX_N PF14226.1 KNZ76457.1 - 1.1e-20 74.3 0.0 2.1e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KNZ76457.1 - 1.4e-12 47.7 0.1 3.9e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PCI PF01399.22 KNZ76459.1 - 3.4e-13 49.8 0.0 6.2e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 PCI domain Peptidase_S10 PF00450.17 KNZ76460.1 - 1.1e-87 294.9 0.0 1.3e-87 294.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4366 PF14283.1 KNZ76460.1 - 0.051 12.9 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) rve PF00665.21 KNZ76464.1 - 0.0079 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RFX1_trans_act PF04589.8 KNZ76467.1 - 0.019 14.7 0.0 0.019 14.7 0.0 2.0 3 0 0 3 3 3 0 RFX1 transcription activation region Sugarporin_N PF11471.3 KNZ76467.1 - 0.086 12.4 1.4 0.21 11.2 1.0 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension PCNA_C PF02747.10 KNZ76468.1 - 1.5e-19 70.2 0.7 3.2e-12 46.4 0.0 2.4 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 KNZ76468.1 - 1.6e-19 69.6 4.3 2.8e-19 68.8 3.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain SDA1 PF05285.7 KNZ76468.1 - 0.0015 17.8 15.5 0.0019 17.5 10.7 1.1 1 0 0 1 1 1 1 SDA1 Trypan_PARP PF05887.6 KNZ76468.1 - 0.0032 17.2 1.8 0.0043 16.8 1.3 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TATR PF03430.8 KNZ76468.1 - 0.091 11.3 7.5 0.11 11.0 5.2 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator ATG27 PF09451.5 KNZ76468.1 - 0.23 10.6 5.9 0.32 10.1 4.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Neur_chan_memb PF02932.11 KNZ76468.1 - 1.3 8.8 5.2 1.8 8.3 3.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 KNZ76468.1 - 1.7 6.2 9.2 1.9 6.0 6.4 1.1 1 0 0 1 1 1 0 Ycf1 Helitron_like_N PF14214.1 KNZ76470.1 - 3.1e-24 85.7 0.3 4.1e-24 85.3 0.2 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.1 KNZ76471.1 - 9.7e-16 58.0 0.1 1.3e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ76471.1 - 0.0093 15.5 0.1 0.0093 15.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) Gemini_AL1 PF00799.15 KNZ76471.1 - 0.0098 15.7 0.1 0.011 15.5 0.1 1.1 1 0 0 1 1 1 1 Geminivirus Rep catalytic domain PIF1 PF05970.9 KNZ76473.1 - 1.4e-50 172.3 0.1 1.5e-50 172.1 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase Viral_helicase1 PF01443.13 KNZ76473.1 - 0.012 15.1 0.1 0.022 14.2 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KNZ76473.1 - 0.033 13.7 0.0 0.051 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KNZ76473.1 - 0.1 12.7 0.1 0.6 10.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Arginase PF00491.16 KNZ76473.1 - 0.12 11.6 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Arginase family ResIII PF04851.10 KNZ76473.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PIF1 PF05970.9 KNZ76474.1 - 7.8e-33 113.9 0.0 8.8e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase BAP PF06639.6 KNZ76474.1 - 0.13 11.9 0.0 0.56 9.9 0.0 1.9 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) Herpes_Helicase PF02689.9 KNZ76475.1 - 8.5e-07 27.1 0.0 9e-07 27.0 0.0 1.0 1 0 0 1 1 1 1 Helicase Amastin PF07344.6 KNZ76477.1 - 0.2 11.2 6.2 4.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF202 PF02656.10 KNZ76477.1 - 0.26 11.5 7.2 0.59 10.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF4131 PF13567.1 KNZ76477.1 - 3.9 6.8 8.1 1.5 8.2 3.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Glyoxal_oxid_N PF07250.6 KNZ76478.1 - 1.1e-36 126.1 0.3 1.8e-33 115.6 0.3 4.4 4 1 0 4 4 4 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KNZ76478.1 - 2e-21 75.9 0.9 4.3e-21 74.8 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Herpes_gE PF02480.11 KNZ76478.1 - 0.038 12.2 0.0 0.054 11.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NAD_binding_8 PF13450.1 KNZ76479.1 - 0.001 19.0 0.2 0.0025 17.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain LANC_like PF05147.8 KNZ76481.1 - 1.9e-32 112.2 0.0 2.9e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Pec_lyase PF09492.5 KNZ76481.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Pectic acid lyase DUF2975 PF11188.3 KNZ76481.1 - 0.16 11.6 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF1917 PF08939.5 KNZ76482.1 - 9.9e-33 113.8 0.0 1.1e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) PSRT PF07636.6 KNZ76482.1 - 0.067 12.6 0.1 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 PSRT DUF4129 PF13559.1 KNZ76482.1 - 0.29 11.1 3.8 1 9.3 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) Fungal_trans PF04082.13 KNZ76485.1 - 5.1e-27 94.3 0.1 1.1e-26 93.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HAD_2 PF13419.1 KNZ76486.1 - 2e-15 57.4 0.0 4e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KNZ76486.1 - 0.00013 21.5 0.0 0.00032 20.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KNZ76486.1 - 0.00071 20.0 0.0 0.0013 19.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase APH PF01636.18 KNZ76487.1 - 0.00022 21.0 0.0 0.00048 19.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ76487.1 - 0.0019 17.3 0.0 0.0045 16.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain RPT PF13446.1 KNZ76487.1 - 0.46 9.9 3.0 0.46 9.9 0.2 2.4 4 0 0 4 4 4 0 A repeated domain in UCH-protein RNase_H PF00075.19 KNZ76488.1 - 6.9e-14 52.3 0.2 1.3e-13 51.4 0.1 1.5 1 0 0 1 1 1 1 RNase H Fucose_iso_N2 PF07882.7 KNZ76488.1 - 5.3 6.6 5.7 0.4 10.3 0.4 1.6 2 0 0 2 2 2 0 L-fucose isomerase, second N-terminal domain zf-RVT PF13966.1 KNZ76489.1 - 0.0053 17.0 0.6 0.0053 17.0 0.4 1.5 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase zf-C4pol PF14260.1 KNZ76489.1 - 0.025 14.5 0.2 0.027 14.4 0.2 1.1 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta PADR1 PF08063.7 KNZ76489.1 - 0.2 11.0 0.9 0.22 10.9 0.4 1.4 1 1 0 1 1 1 0 PADR1 (NUC008) domain APH PF01636.18 KNZ76491.1 - 0.00019 21.2 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KNZ76491.1 - 0.048 12.8 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.20 KNZ76491.1 - 0.057 12.5 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Imm15 PF15590.1 KNZ76492.1 - 0.11 11.5 0.1 0.34 10.0 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 15 LRR_4 PF12799.2 KNZ76494.1 - 1.5 8.5 5.5 84 2.9 0.0 5.4 5 3 1 6 6 6 0 Leucine Rich repeats (2 copies) APH PF01636.18 KNZ76496.1 - 8.7e-05 22.3 0.1 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KNZ76496.1 - 0.039 13.0 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.20 KNZ76496.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain MFS_1 PF07690.11 KNZ76497.1 - 8.4e-40 136.5 39.9 8.4e-40 136.5 27.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ76497.1 - 1.2e-12 47.1 32.5 3.2e-12 45.7 22.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KNZ76497.1 - 2.8e-07 29.1 1.5 5.6e-07 28.1 1.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PAGK PF15284.1 KNZ76497.1 - 0.048 13.4 3.4 0.074 12.8 0.1 3.0 3 0 0 3 3 3 0 Phage-encoded virulence factor ESSS PF10183.4 KNZ76497.1 - 1.2 9.6 0.0 1.2 9.6 0.0 2.8 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) zf-DHHC PF01529.15 KNZ76497.1 - 2.5 7.4 7.2 28 4.0 1.7 3.3 1 1 1 2 2 2 0 DHHC palmitoyltransferase Glyco_hydro_61 PF03443.9 KNZ76498.1 - 1e-53 182.3 0.1 2.2e-53 181.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 SSP160 PF06933.6 KNZ76498.1 - 7.7 4.3 21.5 11 3.8 14.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glyco_hydro_61 PF03443.9 KNZ76499.1 - 9.6e-12 45.1 0.3 1e-11 45.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 KNZ76500.1 - 5.8e-34 117.8 0.0 6.4e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ATP-synt_B PF00430.13 KNZ76501.1 - 0.034 13.9 1.3 0.056 13.2 0.9 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) WW PF00397.21 KNZ76502.1 - 0.0002 21.1 0.7 0.0002 21.1 0.5 2.2 2 0 0 2 2 2 1 WW domain Paf67 PF10255.4 KNZ76502.1 - 0.033 13.0 1.5 0.045 12.6 1.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Exo_endo_phos PF03372.18 KNZ76503.1 - 0.073 12.9 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family zf-RING_3 PF14369.1 KNZ76505.1 - 0.043 13.8 0.4 0.088 12.8 0.3 1.5 1 0 0 1 1 1 0 zinc-finger zf-RVT PF13966.1 KNZ76505.1 - 0.59 10.4 5.0 0.37 11.1 0.9 2.0 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase WW PF00397.21 KNZ76506.1 - 0.016 15.0 1.3 0.016 15.0 0.9 2.0 2 0 0 2 2 2 0 WW domain Paf67 PF10255.4 KNZ76506.1 - 0.13 11.1 0.6 0.18 10.6 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Acetyltransf_3 PF13302.1 KNZ76507.1 - 2e-12 47.4 0.0 2.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Grp1_Fun34_YaaH PF01184.14 KNZ76508.1 - 2e-66 223.2 15.0 2.7e-66 222.8 10.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF373 PF04123.8 KNZ76508.1 - 0.34 9.8 4.0 0.52 9.2 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) gag-asp_proteas PF13975.1 KNZ76509.1 - 0.0094 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KNZ76509.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.4 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KNZ76509.1 - 0.087 13.3 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease DUF2967 PF11179.3 KNZ76510.1 - 0.0042 16.6 0.0 0.0047 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2967) Chromo PF00385.19 KNZ76512.1 - 1.1e-12 47.4 1.9 1.5e-12 46.9 1.3 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3804 PF12707.2 KNZ76516.1 - 0.09 12.3 0.0 0.098 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) DIOX_N PF14226.1 KNZ76521.1 - 5.2e-20 72.1 0.1 9.4e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KNZ76521.1 - 2.8e-13 50.0 0.3 2.2e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily APH PF01636.18 KNZ76523.1 - 3.4e-06 26.9 0.2 6e-05 22.8 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ76523.1 - 0.00061 19.0 0.0 0.0008 18.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KNZ76523.1 - 0.0059 15.7 0.0 0.052 12.6 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_3 PF07859.8 KNZ76525.1 - 1.8e-51 174.7 0.0 1.8e-51 174.7 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ76525.1 - 0.00015 21.5 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KNZ76525.1 - 0.00074 18.3 2.4 0.0048 15.6 1.7 2.1 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KNZ76525.1 - 0.0059 15.8 0.0 0.021 14.0 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 KNZ76525.1 - 0.0062 15.4 0.1 0.015 14.1 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme DUF2424 PF10340.4 KNZ76525.1 - 0.041 12.5 0.1 0.44 9.1 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Glyco_hydro_92 PF07971.7 KNZ76527.1 - 2.1e-149 498.3 0.4 2.6e-149 498.0 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 p450 PF00067.17 KNZ76528.1 - 9.4e-52 176.0 0.0 1.3e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cu-oxidase PF00394.17 KNZ76529.1 - 7.7e-43 146.1 0.1 6.3e-38 130.1 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KNZ76529.1 - 4.1e-37 126.4 0.8 5.6e-35 119.6 0.0 3.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KNZ76529.1 - 3.9e-36 123.5 3.9 8.5e-35 119.2 0.1 2.8 2 1 0 2 2 2 2 Multicopper oxidase DUF619 PF04768.8 KNZ76530.1 - 8.6e-42 142.4 0.0 1.3e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 KNZ76530.1 - 6.8e-26 90.9 0.0 1.7e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 KNZ76530.1 - 3.2e-18 66.1 0.0 8.9e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 Amino acid kinase family GFO_IDH_MocA PF01408.17 KNZ76530.1 - 0.098 13.1 0.0 0.49 10.9 0.0 2.2 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold Metallophos PF00149.23 KNZ76531.1 - 2.3e-39 134.8 0.2 3.6e-39 134.2 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zn_clus PF00172.13 KNZ76533.1 - 2.2e-10 40.2 8.7 3.5e-10 39.6 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KNZ76533.1 - 1.5e-09 37.0 1.3 3.2e-06 26.2 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Abhydrolase_5 PF12695.2 KNZ76534.1 - 1.2e-19 70.4 0.0 1.6e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ76534.1 - 3.8e-18 66.1 0.0 2.3e-16 60.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KNZ76534.1 - 1.7e-06 27.9 0.1 0.00024 20.8 0.0 2.4 2 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 KNZ76534.1 - 7.6e-05 22.3 0.0 0.00033 20.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KNZ76534.1 - 0.0013 18.0 0.0 0.68 9.1 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KNZ76534.1 - 0.0015 18.0 0.0 0.017 14.5 0.0 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KNZ76534.1 - 0.022 13.9 0.0 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2305 PF10230.4 KNZ76534.1 - 0.052 12.9 0.1 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) AXE1 PF05448.7 KNZ76534.1 - 0.052 12.0 0.0 0.38 9.2 0.0 2.2 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) UQ_con PF00179.21 KNZ76536.1 - 1.2e-44 151.0 0.0 1.6e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KNZ76536.1 - 0.00014 21.6 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KNZ76536.1 - 0.077 12.6 0.1 0.14 11.8 0.1 1.4 1 1 0 1 1 1 0 UEV domain zf-RING_2 PF13639.1 KNZ76537.1 - 1.3e-13 50.5 7.2 2.2e-13 49.7 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KNZ76537.1 - 8.2e-08 32.2 2.8 1.5e-07 31.3 2.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KNZ76537.1 - 6e-07 29.0 1.7 9.6e-07 28.4 1.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KNZ76537.1 - 1.2e-06 28.0 1.8 2e-06 27.3 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ76537.1 - 2.2e-06 27.5 4.4 3.7e-06 26.8 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ76537.1 - 2.3e-06 27.1 2.9 3.6e-06 26.5 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KNZ76537.1 - 0.00054 19.7 1.1 0.0014 18.4 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KNZ76537.1 - 0.013 15.5 5.2 0.027 14.5 3.6 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KNZ76537.1 - 0.015 15.2 1.6 0.03 14.2 1.1 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KNZ76537.1 - 0.041 13.4 1.9 0.074 12.6 1.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Daxx PF03344.10 KNZ76537.1 - 0.12 10.8 2.9 0.18 10.2 2.0 1.2 1 0 0 1 1 1 0 Daxx Family WD40_alt PF14077.1 KNZ76537.1 - 0.12 12.0 1.7 0.3 10.7 1.2 1.7 1 0 0 1 1 1 0 Alternative WD40 repeat motif PHD PF00628.24 KNZ76537.1 - 0.19 11.4 2.8 0.32 10.7 1.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.1 KNZ76537.1 - 0.25 11.0 0.7 0.74 9.5 0.1 2.0 1 1 1 2 2 2 0 RING-type zinc-finger Glyco_transf_90 PF05686.7 KNZ76540.1 - 6.9e-07 28.2 0.3 6.4e-05 21.8 0.0 3.0 3 1 0 3 3 3 2 Glycosyl transferase family 90 Pyridox_oxidase PF01243.15 KNZ76541.1 - 1.7e-06 27.9 0.0 2.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase EBP PF05241.7 KNZ76542.1 - 2.2e-08 33.3 3.7 2.7e-08 33.0 2.6 1.1 1 0 0 1 1 1 1 Emopamil binding protein Trypan_PARP PF05887.6 KNZ76543.1 - 0.066 13.0 7.1 0.096 12.5 4.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Bestrophin PF01062.16 KNZ76544.1 - 5.3e-52 176.5 5.6 9.1e-34 116.7 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel tRNA-synt_2b PF00587.20 KNZ76545.1 - 3.3e-66 222.1 0.0 5.6e-66 221.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KNZ76545.1 - 1.4e-21 76.2 0.1 4e-21 74.7 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain DUF1423 PF07227.6 KNZ76550.1 - 4.3 5.8 7.8 5.1 5.6 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Peptidase_S49_N PF08496.5 KNZ76552.1 - 1.7 8.4 4.2 5.6 6.7 0.5 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal rve PF00665.21 KNZ76555.1 - 5.6e-05 23.2 0.0 9.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.12 KNZ76556.1 - 0.00057 19.8 2.4 0.0052 16.8 0.2 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein YqjK PF13997.1 KNZ76556.1 - 0.17 12.0 2.0 27 5.0 0.1 3.2 2 1 1 3 3 3 0 YqjK-like protein PI-PLC-X PF00388.14 KNZ76557.1 - 1.9e-51 173.2 0.0 3.3e-51 172.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KNZ76557.1 - 3.2e-37 127.1 0.0 5.5e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 KNZ76557.1 - 2.1e-06 27.4 0.0 6.5e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 KNZ76557.1 - 0.00035 20.6 0.0 0.0015 18.6 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KNZ76557.1 - 0.004 16.3 0.0 0.71 9.3 0.0 2.9 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.1 KNZ76557.1 - 0.14 11.8 1.9 0.2 11.3 0.0 2.4 2 1 0 2 2 2 0 EF hand FoP_duplication PF13865.1 KNZ76558.1 - 0.013 15.9 0.0 0.059 13.8 0.0 2.0 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Glyco_tranf_2_3 PF13641.1 KNZ76559.1 - 1.2e-24 87.3 0.0 1.8e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KNZ76559.1 - 1.7e-09 37.6 0.0 2.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KNZ76559.1 - 3.6e-09 36.1 0.1 9.1e-09 34.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 KNZ76559.1 - 4.6e-06 26.4 6.9 8.2e-06 25.6 4.8 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 KNZ76559.1 - 0.028 12.8 0.7 0.083 11.2 0.5 1.8 1 1 0 1 1 1 0 Chitin synthase Peptidase_M24 PF00557.19 KNZ76560.1 - 4.7e-26 91.6 0.0 1.8e-18 66.8 0.0 2.3 1 1 1 2 2 2 2 Metallopeptidase family M24 Creatinase_N PF01321.13 KNZ76560.1 - 2.2e-19 70.2 0.1 9.7e-18 64.9 0.0 2.5 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain NOGCT PF08155.6 KNZ76561.1 - 2.8e-28 97.3 1.8 2.8e-28 97.3 1.3 2.0 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.9 KNZ76561.1 - 1.1e-27 95.6 0.1 2.1e-27 94.7 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KNZ76561.1 - 5.2e-17 61.8 0.0 1.4e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KNZ76561.1 - 2e-10 40.1 0.0 4.7e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KNZ76561.1 - 0.0031 17.9 0.0 0.0082 16.6 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 KNZ76561.1 - 0.0039 16.3 0.0 0.043 12.9 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KNZ76561.1 - 0.0099 15.7 0.9 2.7 7.8 0.0 3.1 3 1 1 4 4 4 1 Dynamin family GTP_EFTU PF00009.22 KNZ76561.1 - 0.02 14.2 0.1 0.19 11.1 0.1 2.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.9 KNZ76561.1 - 0.11 12.2 0.1 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SURF2 PF05477.6 KNZ76561.1 - 3.7 6.6 11.2 4 6.4 2.3 2.5 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) LRR_4 PF12799.2 KNZ76563.1 - 0.96 9.1 4.6 4.2 7.0 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KNZ76563.1 - 1.8 8.8 4.0 8.6 6.7 0.1 4.1 6 0 0 6 6 6 0 Leucine Rich repeat G-alpha PF00503.15 KNZ76564.1 - 2.7e-87 293.0 0.0 3.5e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KNZ76564.1 - 5.7e-07 28.9 0.0 0.0045 16.2 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family NACHT PF05729.7 KNZ76564.1 - 0.035 13.7 0.1 0.64 9.6 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_29 PF13555.1 KNZ76564.1 - 0.051 13.1 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 KNZ76564.1 - 0.073 12.2 0.0 0.66 9.0 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Collagen PF01391.13 KNZ76566.1 - 3.2e-09 36.1 32.5 3.2e-09 36.1 22.5 2.0 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) WD40 PF00400.27 KNZ76567.1 - 0.028 14.2 5.0 6.9 6.7 0.3 4.6 4 0 0 4 4 4 0 WD domain, G-beta repeat tRNA_lig_kinase PF08303.6 KNZ76567.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 tRNA ligase kinase domain Sugar_tr PF00083.19 KNZ76568.1 - 9.2e-95 317.8 27.4 1.6e-94 317.0 19.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ76568.1 - 3.3e-28 98.4 39.2 8.1e-17 60.9 6.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily PSDC PF12588.3 KNZ76569.1 - 8.3e-38 129.1 0.2 4.8e-36 123.4 0.1 2.2 1 1 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 KNZ76569.1 - 1.6e-34 118.9 0.0 2.4e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Ehrlichia_rpt PF09528.5 KNZ76572.1 - 0.14 10.2 6.0 0.16 10.0 4.1 1.0 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Neuregulin PF02158.10 KNZ76572.1 - 0.16 10.6 0.4 0.23 10.1 0.2 1.2 1 1 0 1 1 1 0 Neuregulin family DUF3682 PF12446.3 KNZ76573.1 - 0.16 12.3 2.8 0.21 11.8 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Chromo PF00385.19 KNZ76575.1 - 6.1e-19 67.4 0.1 7.6e-19 67.1 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SF3a60_bindingd PF12108.3 KNZ76575.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Terpene_synth_C PF03936.11 KNZ76577.1 - 2.8e-15 56.2 0.1 3.6e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF577 PF04510.7 KNZ76577.1 - 0.0033 17.1 0.0 0.026 14.2 0.0 2.1 1 1 1 2 2 2 1 Family of unknown function (DUF577) DUF3093 PF11292.3 KNZ76578.1 - 1.2 8.9 14.4 1.6 8.5 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) DUF4293 PF14126.1 KNZ76578.1 - 1.3 8.9 8.6 3.1 7.7 5.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) RR_TM4-6 PF06459.7 KNZ76580.1 - 0.23 11.2 0.9 0.3 10.9 0.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PI-PLC-X PF00388.14 KNZ76581.1 - 2.8e-52 176.0 0.0 5.4e-52 175.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KNZ76581.1 - 1.5e-34 118.5 0.0 4.5e-34 116.9 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KNZ76581.1 - 9.8e-10 38.3 2.3 9.7e-08 31.9 0.0 2.5 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 KNZ76581.1 - 4e-08 32.9 0.0 1.2e-07 31.4 0.0 1.8 2 0 0 2 2 1 1 C2 domain EF-hand_10 PF14788.1 KNZ76581.1 - 0.00013 21.5 2.1 0.00032 20.2 1.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KNZ76581.1 - 0.00015 21.8 0.7 0.0004 20.4 0.5 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KNZ76581.1 - 0.0034 16.5 0.7 0.058 12.7 0.1 2.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KNZ76581.1 - 0.014 14.9 0.5 0.07 12.7 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair MSP1_C PF07462.6 KNZ76581.1 - 0.024 13.0 0.0 0.044 12.1 0.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus EF-hand_4 PF12763.2 KNZ76581.1 - 0.027 14.1 0.3 0.075 12.7 0.2 1.8 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.1 KNZ76581.1 - 0.034 14.0 2.2 0.13 12.1 0.6 2.7 2 0 0 2 2 2 0 EF-hand domain IBR PF01485.16 KNZ76583.1 - 9.8e-17 60.5 19.6 4.3e-11 42.5 11.2 2.7 2 1 0 2 2 2 2 IBR domain DUF1488 PF07369.6 KNZ76583.1 - 0.011 15.6 0.3 6.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) zf-RING_2 PF13639.1 KNZ76583.1 - 0.025 14.3 9.9 0.025 14.3 6.9 2.9 3 0 0 3 3 3 0 Ring finger domain CppA_C PF14507.1 KNZ76583.1 - 0.19 11.8 3.3 4.7 7.4 0.0 2.2 1 1 0 2 2 2 0 CppA C-terminal zf-C3HC4_3 PF13920.1 KNZ76583.1 - 9.2 6.0 23.5 6.3 6.5 4.8 3.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_6 PF12697.2 KNZ76585.1 - 1.6e-09 37.9 0.1 2.3e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ76585.1 - 0.0072 16.0 0.0 0.016 15.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PC-Esterase PF13839.1 KNZ76586.1 - 2.6e-07 30.7 0.0 2e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Imm39 PF15600.1 KNZ76586.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 39 Asp PF00026.18 KNZ76590.1 - 5.7e-62 209.7 0.5 5.7e-62 209.7 0.4 1.8 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNZ76590.1 - 7e-10 39.0 1.0 2.3e-09 37.4 0.7 2.0 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KNZ76590.1 - 0.0034 17.8 1.7 0.025 15.0 0.2 3.2 2 1 1 3 3 3 1 Aspartyl protease 7TM_GPCR_Sri PF10327.4 KNZ76591.1 - 0.019 13.9 0.1 0.026 13.4 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Asp_protease_2 PF13650.1 KNZ76593.1 - 0.00017 22.0 0.0 0.00036 20.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KNZ76593.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1814 PF08843.6 KNZ76594.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF1814) Dus PF01207.12 KNZ76597.1 - 7e-71 238.5 0.0 1e-70 238.0 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 KNZ76597.1 - 0.00046 19.3 0.0 0.00074 18.6 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KNZ76597.1 - 0.016 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein ALAD PF00490.16 KNZ76597.1 - 0.14 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase PHZA_PHZB PF03284.8 KNZ76601.1 - 0.035 13.2 0.0 0.045 12.8 0.0 1.1 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B DUF924 PF06041.6 KNZ76601.1 - 0.09 12.5 0.1 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) WD40 PF00400.27 KNZ76605.1 - 2.7e-16 58.7 8.6 0.0037 17.0 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KNZ76605.1 - 0.015 14.1 0.0 0.74 8.4 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like Nbas_N PF15492.1 KNZ76605.1 - 0.11 11.5 0.1 4 6.4 0.0 2.9 1 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 KNZ76605.1 - 0.12 12.1 1.0 1.7 8.3 0.1 3.0 2 2 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 KNZ76605.1 - 8.6 6.7 7.7 83 3.6 0.0 4.3 4 1 1 5 5 5 0 PQQ-like domain NUDIX PF00293.23 KNZ76606.1 - 5.9e-11 42.1 0.0 1e-10 41.3 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain adh_short PF00106.20 KNZ76609.1 - 7.3e-33 113.8 3.4 9.5e-33 113.4 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ76609.1 - 5.8e-24 85.1 0.1 7.2e-24 84.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ76609.1 - 7.3e-12 45.3 2.0 1.1e-11 44.7 1.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KNZ76609.1 - 0.00075 19.0 0.2 0.0024 17.3 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KNZ76609.1 - 0.066 13.0 0.4 0.066 13.0 0.3 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HHH_5 PF14520.1 KNZ76609.1 - 0.067 13.3 0.2 2.7 8.2 0.1 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain WD40 PF00400.27 KNZ76610.1 - 1.4e-16 59.6 6.8 0.0016 18.2 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KNZ76610.1 - 0.0092 15.4 0.1 2.2 7.8 0.0 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain HD PF01966.17 KNZ76613.1 - 5.2e-07 29.7 0.0 7.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 HD domain GPP34 PF05719.6 KNZ76613.1 - 0.062 13.3 0.0 0.25 11.3 0.0 1.8 1 1 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) EF1_GNE PF00736.14 KNZ76615.1 - 2.5e-33 113.6 3.1 4.3e-33 112.8 2.1 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KNZ76615.1 - 9e-14 51.3 5.2 9e-14 51.3 3.6 2.0 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KNZ76615.1 - 3.6e-05 24.1 0.0 8.6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KNZ76615.1 - 0.017 14.9 0.1 0.15 11.9 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SP2 PF03014.9 KNZ76615.1 - 0.045 11.6 0.1 0.061 11.2 0.1 1.1 1 0 0 1 1 1 0 Structural protein 2 GST_C PF00043.20 KNZ76615.1 - 0.11 12.5 0.1 0.82 9.6 0.0 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.2 KNZ76616.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 F-box-like Imm29 PF15575.1 KNZ76617.1 - 0.026 14.1 2.1 0.032 13.8 1.5 1.2 1 0 0 1 1 1 0 Immunity protein 29 Phasin_2 PF09361.5 KNZ76617.1 - 0.12 12.3 3.4 0.33 11.0 2.0 1.9 1 1 1 2 2 2 0 Phasin protein LMBR1 PF04791.11 KNZ76617.1 - 0.12 10.9 1.6 0.13 10.8 1.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein GlutR_dimer PF00745.15 KNZ76617.1 - 0.91 9.5 11.4 1.3 8.9 1.5 2.3 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain ADIP PF11559.3 KNZ76617.1 - 1 9.2 13.7 1.6 8.6 5.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.8 KNZ76617.1 - 1.3 8.0 4.7 1.6 7.7 3.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.10 KNZ76617.1 - 1.4 8.0 7.4 1.5 7.8 5.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.5 KNZ76617.1 - 1.7 8.7 5.3 16 5.6 0.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Relaxase PF03432.9 KNZ76617.1 - 2.5 7.4 9.3 0.59 9.4 3.5 1.8 1 1 1 2 2 2 0 Relaxase/Mobilisation nuclease domain DUF342 PF03961.8 KNZ76617.1 - 5.6 5.2 6.3 6.4 5.0 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) EAP30 PF04157.11 KNZ76617.1 - 7.9 5.5 8.4 0.85 8.7 2.5 1.8 2 1 0 2 2 2 0 EAP30/Vps36 family IncA PF04156.9 KNZ76617.1 - 8.4 5.9 15.4 94 2.5 10.6 2.0 1 1 0 1 1 1 0 IncA protein DUF202 PF02656.10 KNZ76618.1 - 0.0017 18.5 8.1 0.0027 17.9 2.6 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF202) SdpI PF13630.1 KNZ76618.1 - 0.97 9.1 5.2 11 5.8 1.6 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family 60KD_IMP PF02096.15 KNZ76619.1 - 6.2e-31 107.6 1.9 8.7e-31 107.1 1.3 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Na_H_Exchanger PF00999.16 KNZ76620.1 - 1.1e-61 208.4 39.9 2.6e-60 203.9 27.6 2.0 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family G-alpha PF00503.15 KNZ76621.1 - 8.2e-121 403.3 0.1 9.3e-121 403.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KNZ76621.1 - 4.3e-07 29.3 0.6 0.0011 18.2 0.1 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.1 KNZ76621.1 - 0.051 13.7 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain TMEM192 PF14802.1 KNZ76622.1 - 0.12 11.1 0.4 0.2 10.4 0.3 1.3 1 0 0 1 1 1 0 TMEM192 family His_Phos_1 PF00300.17 KNZ76624.1 - 4.2e-06 26.9 0.0 5e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KNZ76624.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.5 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Asp_protease_2 PF13650.1 KNZ76625.1 - 1.9e-05 25.0 0.0 5.4e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease NSP10 PF09401.5 KNZ76625.1 - 0.017 14.8 0.0 0.045 13.4 0.0 1.8 1 0 0 1 1 1 0 RNA synthesis protein NSP10 Asp_protease PF09668.5 KNZ76625.1 - 0.044 13.3 0.2 0.093 12.2 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF3723 PF12520.3 KNZ76629.1 - 0.091 11.2 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) PEMT PF04191.8 KNZ76631.1 - 1.2e-52 176.4 11.0 3.6e-30 104.2 1.2 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase PID PF00640.18 KNZ76631.1 - 0.022 14.7 0.0 0.083 12.8 0.0 1.9 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) YebG PF07130.7 KNZ76631.1 - 0.17 11.5 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 YebG protein Aminotran_3 PF00202.16 KNZ76632.1 - 2.3e-95 319.3 0.0 2e-94 316.2 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KNZ76632.1 - 0.00085 18.5 0.0 0.0064 15.6 0.0 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KNZ76632.1 - 0.0042 16.0 0.0 0.0074 15.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II zf-DHHC PF01529.15 KNZ76633.1 - 7.2e-37 126.4 6.8 7.2e-37 126.4 4.7 1.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase DsbD_2 PF13386.1 KNZ76633.1 - 0.034 13.8 2.2 0.076 12.7 0.1 2.1 2 0 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region ATX_III PF08098.6 KNZ76633.1 - 0.15 11.9 2.9 0.32 10.8 2.0 1.5 1 0 0 1 1 1 0 Anemonia sulcata toxin III family HemY_N PF07219.8 KNZ76633.1 - 3.4 7.2 8.1 0.55 9.8 0.1 2.6 3 0 0 3 3 3 0 HemY protein N-terminus Cullin_binding PF03556.10 KNZ76634.1 - 4.4e-30 104.2 0.1 5e-19 68.5 0.0 2.3 2 0 0 2 2 2 2 Cullin binding UBA_4 PF14555.1 KNZ76634.1 - 4.4e-05 22.9 0.0 0.00012 21.5 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain E1-E2_ATPase PF00122.15 KNZ76638.1 - 2.5e-23 82.3 0.0 2.5e-23 82.3 0.0 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KNZ76638.1 - 4.8e-17 63.0 0.0 8.9e-16 58.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KNZ76638.1 - 1.5e-11 44.7 0.1 3.7e-11 43.5 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KNZ76638.1 - 0.00011 22.1 0.0 0.00046 20.0 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KNZ76638.1 - 0.00018 21.1 0.1 0.00054 19.6 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Herpes_Helicase PF02689.9 KNZ76639.1 - 1.7e-08 32.7 0.0 1.8e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ76639.1 - 0.029 14.4 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.9 KNZ76640.1 - 1.4e-32 113.0 0.1 1.5e-32 112.9 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.9 KNZ76641.1 - 1.1e-07 31.1 0.0 1.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 KNZ76641.1 - 0.0012 18.6 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 KNZ76641.1 - 0.0067 16.4 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 KNZ76641.1 - 0.085 12.3 0.3 0.13 11.7 0.2 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KNZ76641.1 - 0.1 12.7 0.0 0.79 9.9 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 KNZ76641.1 - 0.11 12.6 0.9 8.7 6.5 0.1 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KNZ76641.1 - 0.41 11.4 2.1 1.5 9.6 0.1 2.0 1 1 1 2 2 2 0 AAA domain Helitron_like_N PF14214.1 KNZ76642.1 - 5.3e-57 192.5 1.4 2e-56 190.6 0.1 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 KNZ76642.1 - 0.0061 15.3 0.2 0.01 14.5 0.2 1.3 1 0 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) 2OG-FeII_Oxy_2 PF13532.1 KNZ76644.1 - 1.4e-10 41.3 0.0 9.4e-10 38.6 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KNZ76644.1 - 0.013 15.7 0.1 0.039 14.2 0.1 1.9 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily Lipase_GDSL PF00657.17 KNZ76646.1 - 4.7e-21 75.7 0.1 5.7e-21 75.4 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KNZ76646.1 - 2.1e-05 24.7 0.5 0.00022 21.4 0.4 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ank_2 PF12796.2 KNZ76647.1 - 4.3e-50 167.9 3.5 7.3e-16 58.2 0.2 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) zf-DHHC PF01529.15 KNZ76647.1 - 2e-35 121.7 4.9 2e-35 121.7 3.4 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.25 KNZ76647.1 - 1.3e-34 116.3 8.3 2.5e-07 30.1 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 KNZ76647.1 - 1.1e-27 95.3 6.2 1.3e-10 41.1 0.0 4.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KNZ76647.1 - 4.6e-26 90.7 11.5 1.8e-10 41.0 0.0 5.3 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ76647.1 - 4.6e-20 69.6 4.3 0.00034 20.5 0.1 6.1 6 0 0 6 6 6 4 Ankyrin repeat stn_TNFRSF12A PF12191.3 KNZ76647.1 - 0.041 13.9 0.7 0.11 12.5 0.5 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF3687 PF12459.3 KNZ76647.1 - 0.057 12.6 1.7 0.18 11.0 1.2 1.8 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein PocR PF10114.4 KNZ76647.1 - 0.28 10.3 2.3 0.47 9.5 1.6 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR ABA_GPCR PF12430.3 KNZ76649.1 - 3.2e-38 130.8 2.8 3.2e-38 130.8 1.9 2.8 2 1 1 3 3 3 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KNZ76649.1 - 3.3e-10 39.8 0.0 8.3e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) DUF2593 PF10767.4 KNZ76649.1 - 0.0069 16.0 1.8 0.0069 16.0 1.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2593) EF1G PF00647.14 KNZ76650.1 - 3.5e-39 132.8 0.0 6.1e-39 132.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KNZ76650.1 - 1.2e-10 41.2 0.1 5.8e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KNZ76650.1 - 1.1e-09 38.3 0.0 3.4e-09 36.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KNZ76650.1 - 3.1e-08 33.3 0.0 8.9e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KNZ76650.1 - 1.6e-07 31.6 0.0 4.3e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KNZ76650.1 - 2.7e-07 30.7 0.0 6.6e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KNZ76650.1 - 5.1e-05 23.1 0.0 0.00022 21.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.14 KNZ76650.1 - 0.013 15.8 4.4 0.035 14.4 2.8 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein SipA PF09052.5 KNZ76650.1 - 0.4 9.0 1.3 0.58 8.4 0.9 1.1 1 0 0 1 1 1 0 Salmonella invasion protein A HNH_2 PF13391.1 KNZ76652.1 - 9.1e-07 28.5 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.1 KNZ76653.1 - 6.1e-06 25.9 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Peptidase_M13_N PF05649.8 KNZ76653.1 - 0.051 12.6 0.0 4.3 6.2 0.0 2.1 1 1 1 2 2 2 0 Peptidase family M13 Asp_protease_2 PF13650.1 KNZ76655.1 - 5.7e-08 33.1 0.0 1.3e-07 31.9 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.5 KNZ76655.1 - 3.3e-05 23.4 0.1 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KNZ76655.1 - 0.022 14.5 0.0 0.04 13.7 0.0 1.5 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KNZ76655.1 - 0.049 13.5 0.1 0.059 13.2 0.1 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Peptidase_A2B PF12384.3 KNZ76655.1 - 0.052 12.8 0.1 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 Ty3 transposon peptidase Striatin PF08232.7 KNZ76656.1 - 2.4 8.4 6.9 0.36 11.1 1.7 1.8 2 0 0 2 2 2 0 Striatin family Bap31 PF05529.7 KNZ76656.1 - 6.6 6.1 6.7 0.38 10.1 0.5 1.8 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like RNase_T PF00929.19 KNZ76657.1 - 7.7e-16 58.8 0.0 3.3e-15 56.7 0.0 2.0 1 1 0 1 1 1 1 Exonuclease Gemini_AL3 PF01407.12 KNZ76658.1 - 0.1 12.0 0.0 0.45 9.9 0.0 1.9 2 0 0 2 2 2 0 Geminivirus AL3 protein CPSF73-100_C PF11718.3 KNZ76659.1 - 8.9e-57 191.9 0.2 1.5e-56 191.1 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KNZ76659.1 - 7.3e-33 113.1 0.0 2.3e-32 111.5 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 KNZ76659.1 - 3.3e-13 49.7 0.2 3.3e-13 49.7 0.2 2.0 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 KNZ76659.1 - 1.2e-10 41.0 0.1 2.6e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 KNZ76659.1 - 5.3e-10 39.1 2.4 7.9e-10 38.5 0.2 2.3 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KNZ76659.1 - 2.5e-07 30.5 0.9 9.4e-06 25.4 0.0 3.2 3 1 0 3 3 3 1 Beta-lactamase superfamily domain DUF3995 PF13160.1 KNZ76660.1 - 0.23 11.5 5.0 0.06 13.3 1.0 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3995) WD40 PF00400.27 KNZ76661.1 - 3.9e-21 74.0 14.4 8.5e-08 31.7 0.1 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat Asp_protease_2 PF13650.1 KNZ76663.1 - 1.9e-05 25.0 0.0 2.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KNZ76663.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_3 PF13456.1 KNZ76664.1 - 0.047 13.4 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like ARF7EP_C PF14949.1 KNZ76664.1 - 0.061 13.7 4.0 0.095 13.1 2.7 1.2 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Terpene_synth_C PF03936.11 KNZ76665.1 - 7.2e-13 48.3 0.0 9.8e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain RrnaAD PF00398.15 KNZ76666.1 - 5.6e-19 68.1 0.0 9.7e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Rnk_N PF14760.1 KNZ76667.1 - 0.23 11.5 2.9 13 5.9 0.2 2.6 2 0 0 2 2 2 0 Rnk N-terminus Terpene_synth_C PF03936.11 KNZ76668.1 - 3.8e-13 49.2 0.1 6e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Helitron_like_N PF14214.1 KNZ76669.1 - 4.3e-62 209.1 0.4 9.5e-62 207.9 0.1 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 KNZ76671.1 - 2.4e-104 349.1 0.0 2.8e-104 348.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ76671.1 - 0.0018 17.8 0.0 0.0034 16.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KNZ76671.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KNZ76671.1 - 0.14 11.6 0.1 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.9 KNZ76672.1 - 0.13 9.9 0.0 0.13 9.9 0.0 1.0 1 0 0 1 1 1 0 Helicase GF_recep_IV PF14843.1 KNZ76673.1 - 0.089 12.4 11.0 0.14 11.8 7.6 1.2 1 0 0 1 1 1 0 Growth factor receptor domain IV zf-CCHC_4 PF14392.1 KNZ76673.1 - 2.2 7.9 15.3 1.1 8.9 0.9 3.0 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC PF00098.18 KNZ76673.1 - 6.8 6.8 13.7 0.086 12.8 1.8 3.1 3 0 0 3 3 3 0 Zinc knuckle DNA_pol3_theta PF06440.6 KNZ76674.1 - 0.029 13.9 0.1 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, theta subunit zf-HIT PF04438.11 KNZ76676.1 - 2.3e-07 30.3 11.3 3.8e-07 29.6 7.8 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 KNZ76676.1 - 0.63 9.9 12.8 1.1 9.1 8.9 1.5 1 0 0 1 1 1 0 MYND finger HSP70 PF00012.15 KNZ76677.1 - 7.3e-160 532.7 0.1 1.8e-159 531.4 0.1 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KNZ76677.1 - 6.6e-10 38.0 0.0 1.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein LSM PF01423.17 KNZ76678.1 - 3.4e-06 26.5 0.0 4.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain DUF747 PF05346.6 KNZ76679.1 - 3.5e-116 387.8 2.9 4.5e-116 387.5 2.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family AAA_22 PF13401.1 KNZ76681.1 - 8.9e-14 51.7 0.0 2.3e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ76681.1 - 8.4e-10 38.9 0.1 1.6e-08 34.7 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KNZ76681.1 - 4.8e-09 36.5 0.0 1.3e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KNZ76681.1 - 4.4e-05 23.2 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 KNZ76681.1 - 0.00046 19.2 0.0 0.034 13.1 0.0 2.3 1 1 0 2 2 2 1 KAP family P-loop domain NACHT PF05729.7 KNZ76681.1 - 0.00088 18.9 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 KNZ76681.1 - 0.00097 18.9 0.0 0.0034 17.1 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 KNZ76681.1 - 0.0024 16.7 0.0 0.004 16.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 KNZ76681.1 - 0.0029 17.5 0.0 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KNZ76681.1 - 0.011 14.5 0.0 0.04 12.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 C-terminus cobW PF02492.14 KNZ76681.1 - 0.011 15.1 0.0 0.037 13.4 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 KNZ76681.1 - 0.022 13.6 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 KNZ76681.1 - 0.023 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 KNZ76681.1 - 0.042 13.3 0.0 0.13 11.7 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 KNZ76681.1 - 0.045 12.6 0.0 0.093 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 KNZ76681.1 - 0.048 13.0 0.0 0.73 9.2 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Miro PF08477.8 KNZ76681.1 - 0.057 13.9 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AFG1_ATPase PF03969.11 KNZ76681.1 - 0.079 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase RNA_helicase PF00910.17 KNZ76681.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AP3B1_C PF14796.1 KNZ76681.1 - 0.24 11.0 7.3 0.05 13.2 0.6 2.8 3 0 0 3 3 3 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal TP6A_N PF04406.9 KNZ76682.1 - 4.8e-19 67.7 0.2 1.4e-18 66.2 0.2 1.7 2 0 0 2 2 2 1 Type IIB DNA topoisomerase Baculo_gp41 PF04700.7 KNZ76682.1 - 0.17 11.3 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region CBM_1 PF00734.13 KNZ76683.1 - 5.6 6.7 5.8 2.7 7.7 1.8 2.0 2 0 0 2 2 2 0 Fungal cellulose binding domain DUF3435 PF11917.3 KNZ76684.1 - 0.053 12.2 4.2 0.081 11.6 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) YPEB PF14620.1 KNZ76684.1 - 0.24 10.3 3.2 0.37 9.7 2.2 1.2 1 0 0 1 1 1 0 YpeB sporulation ARL6IP6 PF15062.1 KNZ76684.1 - 0.24 11.3 0.8 0.57 10.1 0.6 1.5 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix DUF812 PF05667.6 KNZ76684.1 - 1.5 7.2 11.6 2.1 6.7 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fmp27_WPPW PF10359.4 KNZ76684.1 - 1.5 7.1 5.1 2.2 6.5 3.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TBPIP PF07106.8 KNZ76684.1 - 2 7.9 7.5 3 7.3 4.8 1.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) LUC7 PF03194.10 KNZ76684.1 - 2.4 7.6 5.9 3.6 7.0 4.1 1.2 1 0 0 1 1 1 0 LUC7 N_terminus DUF966 PF06136.8 KNZ76684.1 - 4.1 6.7 7.3 1.4 8.3 3.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF966) CPSF100_C PF13299.1 KNZ76684.1 - 4.9 7.3 6.6 0.61 10.2 1.2 1.9 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal HK PF02110.10 KNZ76685.1 - 3.2e-71 239.3 2.1 3.3e-71 239.3 0.3 1.9 2 1 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KNZ76685.1 - 2.6e-52 176.5 0.8 1.3e-51 174.2 0.2 2.2 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI SUR7 PF06687.7 KNZ76686.1 - 1.5e-20 73.7 8.8 2.4e-20 73.0 6.1 1.4 1 1 0 1 1 1 1 SUR7/PalI family Tetraspannin PF00335.15 KNZ76686.1 - 0.0024 17.1 2.3 0.0024 17.1 1.6 2.1 1 1 1 2 2 2 1 Tetraspanin family DUF2628 PF10947.3 KNZ76686.1 - 0.01 15.6 1.9 0.01 15.6 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DUF2301 PF10063.4 KNZ76686.1 - 0.087 13.0 0.4 0.087 13.0 0.3 2.1 3 0 0 3 3 3 0 Uncharacterized integral membrane protein (DUF2301) DUF4229 PF14012.1 KNZ76686.1 - 1.4 8.8 13.3 1.1 9.2 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4229) Claudin_3 PF06653.6 KNZ76686.1 - 3.2 7.4 7.4 18 5.0 5.1 2.1 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Acyl_transf_3 PF01757.17 KNZ76686.1 - 3.6 6.3 13.8 8.8 5.0 9.5 1.6 1 1 0 1 1 1 0 Acyltransferase family Claudin_2 PF13903.1 KNZ76686.1 - 7.7 6.1 20.7 9.2 5.9 11.0 2.6 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF4293 PF14126.1 KNZ76688.1 - 0.41 10.5 11.8 0.044 13.7 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) APH PF01636.18 KNZ76689.1 - 1.3e-11 44.6 0.0 2.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KNZ76689.1 - 3e-07 29.4 0.0 0.0018 16.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Lyase_8 PF02278.13 KNZ76691.1 - 3.1e-33 115.3 1.9 3.1e-33 115.3 0.2 1.7 2 0 0 2 2 2 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 KNZ76691.1 - 1.3e-16 60.4 0.3 2e-16 59.7 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain F-box-like PF12937.2 KNZ76692.1 - 5.7e-08 32.3 2.9 3.3e-07 29.9 0.5 3.2 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KNZ76692.1 - 0.23 11.1 2.2 1.1 8.9 0.0 3.0 3 0 0 3 3 3 0 F-box domain Pro_CA PF00484.14 KNZ76693.1 - 1e-31 110.0 0.0 1.8e-31 109.2 0.0 1.4 1 1 0 1 1 1 1 Carbonic anhydrase UBN2_2 PF14227.1 KNZ76695.1 - 6.8e-14 51.4 0.0 8.8e-14 51.0 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ76695.1 - 1.3e-08 34.6 0.0 1.8e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 KNZ76695.1 - 2.2e-07 30.1 0.6 2.2e-07 30.1 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) RNase_PH PF01138.16 KNZ76697.1 - 1.8e-15 57.4 2.3 2.5e-15 56.9 1.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 GHMP_kinases_N PF00288.21 KNZ76697.1 - 0.25 11.4 2.6 0.62 10.1 1.8 1.7 1 0 0 1 1 1 0 GHMP kinases N terminal domain ABC_tran PF00005.22 KNZ76698.1 - 3e-29 102.0 0.0 1.6e-14 54.3 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KNZ76698.1 - 3.7e-07 30.3 0.2 0.0026 17.7 0.0 2.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KNZ76698.1 - 0.00011 21.6 0.1 0.013 15.0 0.0 2.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 KNZ76698.1 - 0.0076 16.1 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KNZ76698.1 - 0.026 14.6 0.1 4.1 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 KNZ76698.1 - 0.047 11.0 0.1 0.061 10.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF258 PF03193.11 KNZ76698.1 - 0.15 11.2 0.0 2.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 cobW PF02492.14 KNZ76698.1 - 0.35 10.2 0.7 0.87 9.0 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain APC10 PF03256.11 KNZ76701.1 - 1.6e-45 155.1 0.0 1.9e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 KNZ76701.1 - 0.0035 17.1 0.0 0.0064 16.3 0.0 1.5 1 1 0 1 1 1 1 F5/8 type C domain SIR2 PF02146.12 KNZ76702.1 - 1.4e-29 103.0 0.0 6.8e-29 100.8 0.0 2.0 1 1 0 1 1 1 1 Sir2 family Saccharop_dh PF03435.13 KNZ76702.1 - 6.1e-23 81.4 0.0 9.3e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KNZ76702.1 - 1.7e-08 34.7 0.0 4.4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KNZ76702.1 - 6.6e-06 25.5 0.1 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KNZ76702.1 - 1.4e-05 23.9 0.0 2.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KNZ76702.1 - 3.4e-05 23.4 0.0 6.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KNZ76702.1 - 0.00045 20.1 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 KNZ76702.1 - 0.004 17.4 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KNZ76702.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.15 KNZ76702.1 - 0.032 14.3 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CBM_1 PF00734.13 KNZ76702.1 - 1.3 8.7 4.7 6.9 6.4 1.0 2.5 2 0 0 2 2 2 0 Fungal cellulose binding domain APH PF01636.18 KNZ76704.1 - 1.5e-07 31.3 0.1 5.4e-07 29.5 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ76704.1 - 7.8e-05 21.9 0.0 9.6e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 KNZ76704.1 - 0.00064 19.3 0.0 0.0016 18.0 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KNZ76704.1 - 0.027 13.5 0.0 0.046 12.7 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1814 PF08843.6 KNZ76707.1 - 7.5e-06 25.9 0.0 1.4e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) DUF4095 PF13338.1 KNZ76707.1 - 0.00014 22.0 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4095) DUF2204 PF09970.4 KNZ76707.1 - 0.08 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) DUF3938 PF13074.1 KNZ76709.1 - 0.059 13.2 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) Maf PF02545.9 KNZ76709.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Maf-like protein Sod_Cu PF00080.15 KNZ76715.1 - 2.7e-08 34.0 1.5 1.2e-07 31.9 1.0 1.8 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Prok-JAB PF14464.1 KNZ76715.1 - 0.086 12.4 0.1 0.1 12.1 0.0 1.3 1 1 0 1 1 1 0 Prokaryotic homologs of the JAB domain CBM_1 PF00734.13 KNZ76716.1 - 3.9e-10 39.1 9.8 3.9e-10 39.1 6.8 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF221 PF02714.10 KNZ76717.1 - 1.5e-40 139.0 14.2 1.5e-40 139.0 9.8 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KNZ76717.1 - 2e-16 59.9 2.0 2e-16 59.9 1.4 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KNZ76717.1 - 0.0024 18.3 1.0 4 8.0 0.1 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4463) DUF3779 PF12621.3 KNZ76717.1 - 0.013 15.3 0.2 0.03 14.2 0.1 1.6 1 0 0 1 1 1 0 Phosphate metabolism protein RRM_6 PF14259.1 KNZ76717.1 - 0.019 14.9 0.0 0.085 12.8 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ76717.1 - 0.046 13.5 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC37_M PF08565.6 KNZ76717.1 - 0.14 11.6 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain DUF4131 PF13567.1 KNZ76717.1 - 0.22 10.9 5.3 1.2 8.4 1.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Peptidase_S9 PF00326.16 KNZ76718.1 - 2.5e-48 164.1 0.4 3.8e-48 163.5 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KNZ76718.1 - 2e-10 40.6 0.0 4.3e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ76718.1 - 1.5e-09 38.0 0.2 3e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KNZ76718.1 - 0.095 11.1 0.0 9.9 4.5 0.0 2.2 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Ribosomal_L10 PF00466.15 KNZ76719.1 - 1.5e-18 66.5 0.0 2e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Tautomerase_2 PF14552.1 KNZ76719.1 - 0.064 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Tautomerase enzyme HEAT_2 PF13646.1 KNZ76720.1 - 8.2e-46 154.2 5.9 4.6e-15 55.6 0.0 4.1 2 2 3 5 5 5 5 HEAT repeats HEAT_PBS PF03130.11 KNZ76720.1 - 3.5e-22 76.5 0.0 0.00037 20.6 0.0 6.5 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.17 KNZ76720.1 - 7.8e-12 44.2 0.1 0.0026 17.6 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 KNZ76720.1 - 4.5e-11 42.8 1.6 0.015 15.8 0.0 5.4 4 2 1 5 5 5 2 HEAT-like repeat Arm PF00514.18 KNZ76720.1 - 0.00015 21.4 0.0 0.34 10.8 0.0 3.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat RNase_H PF00075.19 KNZ76721.1 - 2.2e-07 31.2 0.4 3.8e-07 30.4 0.3 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KNZ76721.1 - 0.0023 17.6 0.4 0.01 15.6 0.3 2.0 1 1 0 1 1 1 1 Reverse transcriptase-like F-box-like PF12937.2 KNZ76722.1 - 2.5e-10 39.9 1.2 6.9e-10 38.4 0.8 1.9 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.1 KNZ76722.1 - 1.8e-07 30.7 1.1 6.1e-06 25.7 0.1 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KNZ76722.1 - 2.2e-06 27.0 0.1 0.0039 16.7 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ76722.1 - 0.00011 21.8 0.1 0.43 10.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ76722.1 - 0.009 16.5 1.0 0.031 14.9 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ76722.1 - 0.28 11.9 2.4 1.3 9.7 1.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.2 KNZ76722.1 - 1.1 8.9 8.4 12 5.6 0.1 4.8 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) CDC37_N PF03234.9 KNZ76723.1 - 9.5e-35 120.5 4.1 1e-34 120.3 1.5 2.0 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KNZ76723.1 - 4.5e-33 114.1 0.0 4.5e-33 114.1 0.0 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KNZ76723.1 - 7.6e-21 73.8 0.0 7.6e-21 73.8 0.0 2.5 3 0 0 3 3 3 1 Cdc37 C terminal domain CR6_interact PF10147.4 KNZ76723.1 - 0.019 14.2 0.6 0.04 13.2 0.4 1.6 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Adaptin_binding PF10199.4 KNZ76724.1 - 1.9e-09 37.9 2.4 9.7e-08 32.3 1.6 2.7 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Methyltransf_11 PF08241.7 KNZ76725.1 - 3e-11 43.6 0.0 1e-10 41.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ76725.1 - 2e-10 40.6 0.0 3.7e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ76725.1 - 4.5e-09 36.8 0.0 8.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ76725.1 - 7.7e-09 35.8 0.0 2.2e-08 34.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNZ76725.1 - 4.1e-08 32.6 0.0 6.9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KNZ76725.1 - 2.9e-07 30.2 0.0 4.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ76725.1 - 3.3e-07 30.3 0.0 8.1e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ76725.1 - 0.00031 21.1 0.0 0.00083 19.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KNZ76725.1 - 0.021 13.8 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_29 PF03141.11 KNZ76725.1 - 0.031 12.6 0.0 0.054 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 KNZ76725.1 - 0.032 13.6 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.10 KNZ76725.1 - 0.037 13.6 0.0 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase FtsJ PF01728.14 KNZ76725.1 - 0.094 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 KNZ76725.1 - 0.097 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 KNZ76725.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SAGA-Tad1 PF12767.2 KNZ76725.1 - 3.8 7.0 9.5 0.25 10.9 1.7 2.4 2 1 1 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit adh_short PF00106.20 KNZ76726.1 - 1.8e-20 73.5 0.0 2.7e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ76726.1 - 3.2e-07 30.1 0.0 4.4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KNZ76726.1 - 3e-06 27.2 0.0 4.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KNZ76726.1 - 0.00011 22.2 0.1 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KNZ76726.1 - 0.0023 17.4 0.0 0.0041 16.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KNZ76726.1 - 0.0029 17.6 0.1 0.0048 17.0 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 KNZ76726.1 - 0.014 14.6 0.1 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family THF_DHG_CYH_C PF02882.14 KNZ76726.1 - 0.11 11.5 0.1 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3466 PF11949.3 KNZ76727.1 - 0.008 14.7 0.9 0.011 14.3 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3466) zf-C3H1 PF10650.4 KNZ76727.1 - 0.024 14.1 0.2 0.042 13.3 0.2 1.4 1 0 0 1 1 1 0 Putative zinc-finger domain Pox_A_type_inc PF04508.7 KNZ76727.1 - 0.3 10.9 4.7 17 5.5 1.2 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SRF-TF PF00319.13 KNZ76728.1 - 5.6e-23 79.9 0.2 9.2e-23 79.2 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) adh_short PF00106.20 KNZ76729.1 - 1.6e-18 67.2 0.1 2.8e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ76729.1 - 7.8e-09 35.4 0.1 1.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KNZ76729.1 - 1e-05 25.6 0.2 1.7e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KNZ76729.1 - 6.1e-05 22.9 0.0 0.00015 21.5 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KNZ76729.1 - 0.00021 20.7 0.1 0.00046 19.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family QRPTase_C PF01729.14 KNZ76729.1 - 0.0022 17.5 0.3 0.01 15.3 0.0 2.1 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain NmrA PF05368.8 KNZ76729.1 - 0.065 12.4 0.1 0.099 11.8 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family NicO PF03824.11 KNZ76730.1 - 4e-23 82.1 0.2 4e-23 82.1 0.1 3.8 3 2 0 3 3 3 1 High-affinity nickel-transport protein Chordopox_A33R PF05966.7 KNZ76730.1 - 0.1 11.3 2.0 0.82 8.4 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus A33R protein MBOAT_2 PF13813.1 KNZ76731.1 - 1.4e-14 53.8 3.8 5.1e-14 52.0 0.7 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Hpt PF01627.18 KNZ76732.1 - 1.3e-11 44.3 0.9 1.8e-11 43.8 0.7 1.3 1 0 0 1 1 1 1 Hpt domain Nucleoporin_C PF03177.9 KNZ76732.1 - 0.0044 15.6 0.9 0.0056 15.2 0.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal NCA2 PF08637.5 KNZ76733.1 - 8.7e-68 228.3 0.0 3.2e-67 226.4 0.0 1.8 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Mod_r PF07200.8 KNZ76734.1 - 2e-17 63.4 9.6 3e-10 40.1 3.2 2.8 2 1 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein LRS4 PF10422.4 KNZ76734.1 - 0.003 16.9 1.3 0.0036 16.6 0.9 1.2 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 APG6 PF04111.7 KNZ76734.1 - 0.0043 16.1 2.3 0.0061 15.6 1.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Rootletin PF15035.1 KNZ76734.1 - 0.054 13.4 6.8 0.1 12.5 4.7 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF964 PF06133.6 KNZ76734.1 - 0.43 10.6 5.9 10 6.1 2.2 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF964) NuA4 PF09340.5 KNZ76736.1 - 1.9e-17 62.6 0.6 1.9e-17 62.6 0.4 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF4294 PF14127.1 KNZ76736.1 - 0.034 13.7 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) DUF1087 PF06465.8 KNZ76736.1 - 0.083 12.8 1.0 0.083 12.8 0.7 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) PBP_like PF12727.2 KNZ76736.1 - 0.096 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 PBP superfamily domain DTHCT PF08070.6 KNZ76736.1 - 0.69 10.6 5.4 0.56 10.8 1.6 2.2 2 1 0 2 2 2 0 DTHCT (NUC029) region AAA PF00004.24 KNZ76737.1 - 7.5e-39 132.9 0.0 1.5e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNZ76737.1 - 3.3e-05 23.9 0.2 0.0024 17.9 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KNZ76737.1 - 0.00033 20.3 0.1 0.0019 17.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KNZ76737.1 - 0.00086 19.2 0.0 0.0095 15.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KNZ76737.1 - 0.0018 17.3 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KNZ76737.1 - 0.0032 17.6 1.1 0.055 13.6 0.3 2.6 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KNZ76737.1 - 0.007 15.7 0.1 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KNZ76737.1 - 0.0088 15.7 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 KNZ76737.1 - 0.011 14.9 0.2 0.038 13.1 0.0 2.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KNZ76737.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KNZ76737.1 - 0.023 14.0 1.0 0.21 10.9 0.1 2.4 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 KNZ76737.1 - 0.028 13.6 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.1 KNZ76737.1 - 0.069 13.9 0.1 0.19 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain Ribosomal_S19 PF00203.16 KNZ76737.1 - 0.091 12.3 0.3 17 5.1 0.0 3.1 3 0 0 3 3 3 0 Ribosomal protein S19 AAA_14 PF13173.1 KNZ76737.1 - 0.092 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KNZ76737.1 - 0.099 12.2 0.1 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KNZ76737.1 - 0.1 12.1 0.6 0.25 10.8 0.2 1.8 2 0 0 2 2 1 0 AAA domain ETC_C1_NDUFA4 PF04800.7 KNZ76738.1 - 5e-29 100.1 0.1 7.2e-29 99.6 0.0 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region RICTOR_N PF14664.1 KNZ76739.1 - 2.1e-94 316.1 0.1 9.3e-93 310.7 0.0 2.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KNZ76739.1 - 1.6e-82 275.8 1.0 8.7e-81 270.2 0.1 3.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KNZ76739.1 - 2.3e-31 108.0 0.0 7.1e-31 106.5 0.0 1.9 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KNZ76739.1 - 1.5e-29 101.7 0.1 1e-26 92.6 0.0 4.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.17 KNZ76739.1 - 9.1e-05 22.2 0.2 8.8 6.7 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 KNZ76739.1 - 0.00016 21.8 0.1 0.14 12.4 0.0 4.0 3 0 0 3 3 3 1 HEAT repeats HR1 PF02185.11 KNZ76739.1 - 0.0047 16.6 8.5 0.012 15.3 5.9 1.7 1 0 0 1 1 1 1 Hr1 repeat Ribosomal_L22 PF00237.14 KNZ76740.1 - 2.3e-30 104.6 0.1 3.2e-30 104.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RasGEF_N PF00618.15 KNZ76741.1 - 1.3e-12 47.7 0.6 4.1e-12 46.1 0.6 1.7 1 1 1 2 2 2 1 RasGEF N-terminal motif RasGEF PF00617.14 KNZ76741.1 - 0.0001 22.1 0.2 0.00018 21.3 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain HECT PF00632.20 KNZ76742.1 - 2.8e-91 306.0 0.0 3.8e-91 305.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KNZ76742.1 - 1.5e-31 107.8 13.7 7.3e-10 38.5 0.3 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.25 KNZ76742.1 - 1.2e-12 47.4 0.0 6.3e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 C2 domain DDE_Tnp_4 PF13359.1 KNZ76743.1 - 0.005 16.4 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Eaf7 PF07904.8 KNZ76745.1 - 4.1e-16 58.7 0.0 6.3e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 FXR1P_C PF12235.3 KNZ76745.1 - 0.49 10.4 9.0 1 9.4 6.2 1.5 1 1 0 1 1 1 0 Fragile X-related 1 protein C terminal P33MONOX PF15302.1 KNZ76745.1 - 5.3 6.5 6.4 18 4.8 0.2 2.2 1 1 1 2 2 2 0 P33 mono-oxygenase Ufd2P_core PF10408.4 KNZ76746.1 - 1.1e-184 615.2 1.8 1.3e-184 615.0 1.2 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core PSD5 PF07637.6 KNZ76746.1 - 0.034 14.1 0.3 3.4 7.7 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1595) Ribosomal_L35p PF01632.14 KNZ76747.1 - 7.6e-13 48.1 4.2 9.5e-13 47.8 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 His_Phos_1 PF00300.17 KNZ76748.1 - 1.1e-24 87.3 0.0 1.4e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PhoU_div PF01865.11 KNZ76748.1 - 0.0067 15.6 0.0 0.0098 15.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF47 zf-AN1 PF01428.11 KNZ76749.1 - 5.3e-19 67.8 29.1 5.6e-11 42.1 4.2 2.9 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 KNZ76749.1 - 0.067 13.4 18.1 0.51 10.6 5.2 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DUF3072 PF11272.3 KNZ76749.1 - 1.8 8.2 5.5 0.25 11.0 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) Pro_isomerase PF00160.16 KNZ76750.1 - 3.9e-48 163.5 0.5 8e-48 162.5 0.4 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KNZ76750.1 - 7.3e-10 38.3 3.4 8.4e-05 22.3 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF4504 PF14953.1 KNZ76751.1 - 0.0049 16.2 0.1 0.052 12.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4504) YndJ PF14158.1 KNZ76752.1 - 0.013 14.6 0.3 0.013 14.5 0.2 1.0 1 0 0 1 1 1 0 YndJ-like protein YwiC PF14256.1 KNZ76752.1 - 0.034 14.2 0.3 0.037 14.1 0.2 1.1 1 0 0 1 1 1 0 YwiC-like protein BTP PF05232.7 KNZ76752.1 - 0.059 13.1 1.2 0.083 12.6 0.8 1.3 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family Nuc_sug_transp PF04142.10 KNZ76752.1 - 0.069 12.2 0.2 0.079 12.0 0.1 1.1 1 0 0 1 1 1 0 Nucleotide-sugar transporter RIO1 PF01163.17 KNZ76753.1 - 3.7e-70 235.1 0.0 3.7e-70 235.1 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 KNZ76753.1 - 5e-05 22.5 0.0 0.00014 21.1 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KNZ76753.1 - 0.00036 19.6 0.5 0.24 10.4 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ76753.1 - 0.0005 19.8 1.1 0.2 11.3 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family ILVD_EDD PF00920.16 KNZ76754.1 - 2.2e-188 626.9 0.0 2.8e-188 626.5 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family Septin PF00735.13 KNZ76755.1 - 1.4e-29 103.0 0.0 4.4e-10 39.0 0.0 3.2 3 0 0 3 3 3 3 Septin Zn_clus PF00172.13 KNZ76755.1 - 4.9e-19 67.9 27.3 2.2e-09 37.0 5.4 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Septin PF00735.13 KNZ76756.1 - 1.4e-47 162.0 0.1 1.1e-18 67.2 0.0 3.2 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.18 KNZ76756.1 - 0.00053 19.9 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Cut8_N PF14482.1 KNZ76756.1 - 0.00066 19.6 0.1 0.00066 19.6 0.1 2.6 2 0 0 2 2 2 1 Cut8 proteasome-binding domain GTP_EFTU PF00009.22 KNZ76756.1 - 0.00077 18.9 0.0 0.003 17.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KNZ76756.1 - 0.0026 18.2 0.1 0.0075 16.7 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 KNZ76756.1 - 0.0048 16.8 0.3 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KNZ76756.1 - 0.0071 16.4 0.0 0.097 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KNZ76756.1 - 0.051 13.3 0.3 10 5.8 0.1 2.4 1 1 1 2 2 2 0 Dynamin family MobB PF03205.9 KNZ76756.1 - 0.076 12.7 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KNZ76756.1 - 0.081 13.2 0.0 0.25 11.6 0.0 2.0 1 1 0 1 1 1 0 ABC transporter Pox_A32 PF04665.7 KNZ76756.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Ribosomal_L2_C PF03947.13 KNZ76757.1 - 6.1e-50 168.3 0.3 1.4e-49 167.2 0.2 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KNZ76757.1 - 3.5e-24 84.5 0.4 5.8e-24 83.8 0.3 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain CM_2 PF01817.16 KNZ76758.1 - 2.2e-08 34.0 0.0 8e-05 22.6 0.0 3.0 2 1 0 2 2 2 2 Chorismate mutase type II DUF1268 PF06896.6 KNZ76758.1 - 0.063 13.6 0.2 12 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1268) GRASP55_65 PF04495.9 KNZ76759.1 - 3.8e-07 30.1 0.0 6.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KNZ76759.1 - 1e-06 28.5 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KNZ76759.1 - 0.047 13.8 0.0 0.076 13.1 0.0 1.5 1 1 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Thi4 PF01946.12 KNZ76760.1 - 1.2e-89 299.3 0.1 1.4e-89 299.0 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KNZ76760.1 - 8.2e-11 41.3 0.1 2.7e-09 36.4 0.2 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KNZ76760.1 - 8.7e-08 31.4 0.2 4.8e-07 29.0 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KNZ76760.1 - 1e-06 28.7 0.2 2.5e-06 27.5 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ76760.1 - 2.7e-06 27.3 0.1 6.8e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KNZ76760.1 - 2.8e-06 26.4 1.4 0.00027 19.9 0.2 2.4 2 1 1 3 3 3 2 FAD binding domain NAD_binding_9 PF13454.1 KNZ76760.1 - 4e-05 23.4 0.1 9.1e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KNZ76760.1 - 4.6e-05 22.6 0.1 6.5e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KNZ76760.1 - 0.00034 19.2 0.2 0.00066 18.2 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KNZ76760.1 - 0.00048 19.1 0.1 0.0024 16.8 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KNZ76760.1 - 0.0087 16.1 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KNZ76760.1 - 0.081 11.5 0.3 0.11 11.0 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 KNZ76760.1 - 0.11 12.9 0.1 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Phage_int_SAM_1 PF02899.12 KNZ76761.1 - 0.073 13.2 0.1 0.34 11.0 0.0 1.9 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF1876 PF08962.6 KNZ76761.1 - 0.1 12.4 0.3 9.6 6.0 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF1876) zf-RVT PF13966.1 KNZ76764.1 - 0.0058 16.9 1.3 0.024 14.9 0.4 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.2 KNZ76764.1 - 0.052 13.3 0.2 0.089 12.6 0.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain UBN2_2 PF14227.1 KNZ76766.1 - 5.4e-09 35.6 0.0 7.3e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ76766.1 - 2.6e-08 33.6 0.0 3.5e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type eIF3g PF12353.3 KNZ76766.1 - 0.061 13.2 0.5 0.093 12.6 0.3 1.3 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.18 KNZ76766.1 - 0.067 13.1 0.6 0.12 12.3 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Mitofilin PF09731.4 KNZ76767.1 - 7.6e-50 170.1 7.9 8.4e-50 170.0 5.5 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF2927 PF11150.3 KNZ76767.1 - 0.0089 15.7 0.5 0.015 15.0 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2927) NAP PF00956.13 KNZ76767.1 - 0.046 12.8 2.0 0.052 12.6 1.4 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) AAA_32 PF13654.1 KNZ76767.1 - 0.062 11.9 4.4 0.068 11.8 3.1 1.1 1 0 0 1 1 1 0 AAA domain DUF3631 PF12307.3 KNZ76768.1 - 0.06 13.2 1.0 0.094 12.6 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3631) TmoB PF06234.7 KNZ76768.1 - 1.8 8.4 4.1 7.2 6.5 0.1 2.6 2 1 1 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) MFS_1 PF07690.11 KNZ76770.1 - 3e-35 121.5 42.0 6.5e-35 120.4 29.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ76770.1 - 7.7e-12 44.5 14.4 7.7e-12 44.5 10.0 3.0 2 2 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KNZ76770.1 - 0.0011 17.3 11.2 0.0011 17.3 7.8 1.5 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ThylakoidFormat PF11264.3 KNZ76771.1 - 0.0021 17.7 0.0 0.0025 17.4 0.0 1.1 1 0 0 1 1 1 1 Thylakoid formation protein eIF-5_eIF-2B PF01873.12 KNZ76772.1 - 2.8e-45 153.0 0.2 4.1e-45 152.4 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 KNZ76772.1 - 0.019 14.2 0.1 0.036 13.3 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding IF2_N PF04760.10 KNZ76772.1 - 0.049 13.2 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region zf-HYPF PF07503.7 KNZ76772.1 - 0.072 12.5 0.1 14 5.2 0.0 2.6 2 0 0 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.5 KNZ76772.1 - 1.7 8.9 4.3 15 5.8 0.0 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain DUF1754 PF08555.5 KNZ76772.1 - 3.5 8.2 10.6 2.5 8.7 2.7 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) PCI PF01399.22 KNZ76773.1 - 1.7e-06 28.3 0.0 4.1e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_12 PF13424.1 KNZ76773.1 - 0.033 14.1 0.0 0.09 12.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ76773.1 - 0.08 12.7 0.2 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ76773.1 - 0.1 12.4 0.2 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 KNZ76774.1 - 1.6e-73 247.0 0.0 1.8e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ76774.1 - 5.2e-32 110.9 0.0 1.3e-31 109.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ76774.1 - 0.00017 20.6 0.0 0.00035 19.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ76774.1 - 0.00088 19.0 0.7 0.71 9.5 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KNZ76774.1 - 0.0013 17.8 0.2 0.002 17.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KNZ76774.1 - 0.096 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YukC PF10140.4 KNZ76774.1 - 0.1 11.1 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC zf-CCCH PF00642.19 KNZ76775.1 - 0.0015 18.1 10.1 0.0033 17.0 2.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KNZ76775.1 - 5.4 7.1 10.8 2.2 8.4 1.6 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type NAD_binding_6 PF08030.7 KNZ76776.1 - 1.6e-24 86.5 0.0 2.5e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KNZ76776.1 - 3.3e-17 62.2 0.1 9.3e-17 60.8 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 KNZ76776.1 - 2.8e-13 50.0 9.2 2.8e-13 50.0 6.3 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 KNZ76776.1 - 0.015 15.8 0.0 0.17 12.4 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4131 PF13567.1 KNZ76776.1 - 0.51 9.7 9.5 1.3 8.4 4.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4286 PF14114.1 KNZ76777.1 - 0.003 17.7 0.0 0.96 9.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4286) EthD PF07110.6 KNZ76777.1 - 0.0038 18.1 0.0 4.1 8.4 0.0 2.3 2 0 0 2 2 2 2 EthD domain DUF2069 PF09842.4 KNZ76777.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) WD40 PF00400.27 KNZ76778.1 - 2.3e-32 109.6 15.8 5.4e-10 38.7 0.0 5.4 4 1 1 5 5 5 4 WD domain, G-beta repeat DUF1513 PF07433.6 KNZ76778.1 - 0.0018 17.2 0.0 0.0072 15.2 0.0 1.8 1 1 1 2 2 2 2 Protein of unknown function (DUF1513) Nbas_N PF15492.1 KNZ76778.1 - 0.0065 15.6 0.1 1.5 7.8 0.0 2.8 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 KNZ76778.1 - 0.01 14.0 2.2 0.39 8.7 0.1 2.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 EIF_2_alpha PF07541.7 KNZ76780.1 - 8.3e-37 125.4 0.0 1.3e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit Peptidase_C13 PF01650.13 KNZ76781.1 - 2.5e-40 138.4 0.1 3.3e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Methyltransf_2 PF00891.13 KNZ76783.1 - 1.8e-35 122.3 0.0 3.8e-35 121.2 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KNZ76783.1 - 0.0014 19.1 0.0 0.0032 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ76783.1 - 0.0035 17.8 0.0 0.0078 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ76783.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ76783.1 - 0.058 12.9 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ76783.1 - 0.071 13.5 0.0 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Cu-oxidase PF00394.17 KNZ76784.1 - 2.1e-41 141.4 2.5 7.6e-41 139.6 0.2 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KNZ76784.1 - 1.1e-37 128.3 2.0 7.7e-35 119.1 0.1 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KNZ76784.1 - 1.3e-33 115.3 10.8 1.1e-29 102.7 0.1 4.0 3 1 0 3 3 3 3 Multicopper oxidase Ras PF00071.17 KNZ76785.1 - 1.5e-58 196.7 0.2 1.7e-58 196.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ76785.1 - 1.7e-18 67.2 0.0 3.4e-18 66.2 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KNZ76785.1 - 2.8e-14 52.7 0.0 3.7e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KNZ76785.1 - 7.2e-08 31.8 0.0 9.1e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KNZ76785.1 - 1.5e-05 24.9 0.0 2e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KNZ76785.1 - 2.6e-05 23.7 0.0 4.8e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KNZ76785.1 - 0.0059 15.8 0.0 0.0087 15.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF4211 PF13926.1 KNZ76785.1 - 0.012 14.9 0.1 0.034 13.5 0.0 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4211) AAA_16 PF13191.1 KNZ76785.1 - 0.038 13.9 0.5 0.16 11.9 0.4 2.1 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.13 KNZ76785.1 - 0.087 11.8 0.0 0.17 10.9 0.0 1.4 2 0 0 2 2 2 0 Septin DUF258 PF03193.11 KNZ76785.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 G-alpha PF00503.15 KNZ76785.1 - 0.25 9.9 2.6 1.7 7.2 0.1 2.4 1 1 2 3 3 3 0 G-protein alpha subunit MFS_1 PF07690.11 KNZ76786.1 - 5.5e-08 31.8 21.3 4.6e-06 25.5 6.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KNZ76787.1 - 5.6e-20 71.5 0.0 1.5e-19 70.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ76787.1 - 1.6e-05 24.0 0.8 0.00026 20.1 0.1 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase BTB PF00651.26 KNZ76788.1 - 1.1e-10 41.5 0.0 3.2e-08 33.5 0.1 3.1 3 0 0 3 3 3 1 BTB/POZ domain Linocin_M18 PF04454.7 KNZ76788.1 - 0.088 11.6 0.3 0.15 10.9 0.2 1.3 1 0 0 1 1 1 0 Encapsulating protein for peroxidase Pkinase PF00069.20 KNZ76790.1 - 1.3e-22 80.2 0.0 7.8e-18 64.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ76790.1 - 0.00091 18.3 0.0 0.033 13.2 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KNZ76791.1 - 1.7e-25 89.6 0.0 1.4e-24 86.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ76791.1 - 0.00049 19.2 0.1 0.35 9.9 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase DEAD PF00270.24 KNZ76792.1 - 3e-41 140.7 0.1 4.8e-41 140.0 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ76792.1 - 1.3e-14 53.7 0.0 3.2e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ76792.1 - 9.3e-06 25.5 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KNZ76792.1 - 0.00028 20.5 0.6 0.0012 18.5 0.1 2.3 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KNZ76792.1 - 0.024 14.1 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain UBN2_3 PF14244.1 KNZ76793.1 - 7e-06 25.6 0.0 0.013 15.1 0.0 2.1 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KNZ76793.1 - 0.00038 19.9 0.0 0.00054 19.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ76793.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Cys_Met_Meta_PP PF01053.15 KNZ76794.1 - 9.2e-17 60.3 0.0 1.1e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SRF-TF PF00319.13 KNZ76795.1 - 1.8e-13 49.4 0.0 2.5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Thiolase_N PF00108.18 KNZ76799.1 - 2.2e-78 262.8 1.0 3.5e-78 262.2 0.7 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KNZ76799.1 - 6.5e-36 122.4 1.5 2e-35 120.8 1.0 1.8 1 1 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KNZ76799.1 - 0.35 10.3 6.0 0.34 10.3 0.2 3.1 4 0 0 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain Pro-rich_19 PF15455.1 KNZ76801.1 - 0.08 11.9 1.9 0.11 11.4 1.3 1.1 1 0 0 1 1 1 0 Proline-rich 19 zf-RVT PF13966.1 KNZ76802.1 - 0.048 13.9 0.5 0.067 13.5 0.3 1.2 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase HSP20 PF00011.16 KNZ76803.1 - 5.2e-05 23.0 0.1 0.0001 22.1 0.1 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PAS_9 PF13426.1 KNZ76804.1 - 3.1e-26 91.7 0.0 1.1e-14 54.6 0.0 3.7 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 KNZ76804.1 - 2.7e-20 72.2 0.0 2e-07 30.7 0.0 4.5 4 1 0 4 4 4 3 PAS fold PAS_3 PF08447.6 KNZ76804.1 - 1.3e-15 57.2 0.0 3.1e-09 36.8 0.0 4.0 3 0 0 3 3 3 3 PAS fold PAS_11 PF14598.1 KNZ76804.1 - 1.6e-10 40.9 0.0 1.8e-05 24.6 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.5 KNZ76804.1 - 3.4e-07 30.2 0.1 0.00089 19.2 0.0 3.8 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.1 KNZ76804.1 - 0.00026 20.7 0.0 0.075 12.9 0.0 2.6 2 0 0 2 2 2 1 PAS domain Retrotrans_gag PF03732.12 KNZ76806.1 - 0.00033 20.6 0.6 0.0005 20.0 0.3 1.4 1 1 0 1 1 1 1 Retrotransposon gag protein GvpH PF05455.6 KNZ76807.1 - 0.08 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 GvpH DUF4632 PF15451.1 KNZ76808.1 - 0.025 14.5 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) DUF3176 PF11374.3 KNZ76808.1 - 0.026 14.3 0.2 0.053 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) FtsX PF02687.16 KNZ76808.1 - 0.043 13.5 3.4 0.47 10.2 0.2 2.8 2 1 0 2 2 2 0 FtsX-like permease family KH_1 PF00013.24 KNZ76809.1 - 0.0001 21.8 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KNZ76809.1 - 0.0028 17.2 0.0 0.0057 16.2 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 KNZ76809.1 - 0.0084 15.7 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 KH domain DUF2414 PF10309.4 KNZ76810.1 - 3.8e-05 23.2 0.0 6.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) FoP_duplication PF13865.1 KNZ76810.1 - 6.9e-05 23.2 20.9 0.0012 19.1 3.8 3.5 3 0 0 3 3 3 3 C-terminal duplication domain of Friend of PRMT1 NmrA PF05368.8 KNZ76811.1 - 4.4e-28 98.1 0.0 5.1e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KNZ76811.1 - 7.6e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF3546 PF12066.3 KNZ76812.1 - 1.9e-15 56.8 0.4 1.1e-14 54.3 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 KNZ76812.1 - 4.9e-10 39.9 0.3 4.9e-10 39.9 0.2 2.8 2 2 0 2 2 2 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 KNZ76812.1 - 2.8e-05 23.5 1.7 9.4e-05 21.9 1.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.2 KNZ76812.1 - 0.0096 16.0 0.9 0.25 11.4 0.0 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KNZ76812.1 - 0.04 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 BED zinc finger zf-C2H2 PF00096.21 KNZ76812.1 - 0.27 11.6 5.0 0.098 13.0 0.9 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Response_reg PF00072.19 KNZ76813.1 - 6.2e-23 80.9 0.1 1.8e-16 60.1 0.1 2.5 2 0 0 2 2 2 2 Response regulator receiver domain ATG2_CAD PF13329.1 KNZ76813.1 - 0.053 13.0 0.2 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif TOBE_2 PF08402.5 KNZ76813.1 - 0.058 13.3 0.2 0.49 10.4 0.1 2.3 2 0 0 2 2 2 0 TOBE domain Oxidored_nitro PF00148.14 KNZ76813.1 - 0.071 11.7 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase DDE_1 PF03184.14 KNZ76814.1 - 6e-39 133.4 0.4 7.6e-39 133.0 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease MIF4G_like PF09088.6 KNZ76815.1 - 1.4e-59 200.7 0.0 3e-59 199.6 0.0 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KNZ76815.1 - 2.9e-42 144.6 0.0 5e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 KNZ76815.1 - 2.2e-05 23.9 0.0 0.00013 21.4 0.0 2.2 2 0 0 2 2 2 1 MIF4G domain PPR_2 PF13041.1 KNZ76816.1 - 3.3e-08 33.3 1.1 0.00094 19.1 0.0 4.9 5 0 0 5 5 5 2 PPR repeat family PPR_1 PF12854.2 KNZ76816.1 - 0.00031 20.1 0.1 0.069 12.6 0.0 3.9 4 0 0 4 4 4 1 PPR repeat Ank_3 PF13606.1 KNZ76816.1 - 0.32 11.3 5.9 7.4 7.1 0.1 3.9 3 0 0 3 3 3 0 Ankyrin repeat JmjC PF02373.17 KNZ76817.1 - 9e-07 29.1 0.0 2.5e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Pkinase PF00069.20 KNZ76817.1 - 0.0001 21.5 0.1 0.025 13.7 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Cupin_8 PF13621.1 KNZ76817.1 - 0.0027 17.2 0.0 0.016 14.7 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain Oxidored_molyb PF00174.14 KNZ76817.1 - 0.079 12.3 0.0 6.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase molybdopterin binding domain RRM_6 PF14259.1 KNZ76818.1 - 4.9e-07 29.6 0.0 2e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KNZ76818.1 - 0.0075 15.8 0.0 0.37 10.4 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ76818.1 - 0.027 14.3 0.0 0.084 12.7 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 KNZ76819.1 - 1.2e-46 159.2 16.4 6.3e-46 156.8 11.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ76819.1 - 3.6e-18 65.4 21.5 3.6e-18 65.4 14.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Kdo PF06293.9 KNZ76820.1 - 0.0061 15.6 0.1 0.014 14.4 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family AP_endonuc_2 PF01261.19 KNZ76821.1 - 3e-17 62.6 0.2 3.9e-16 58.9 0.0 2.3 2 1 0 2 2 2 1 Xylose isomerase-like TIM barrel DUF1848 PF08902.6 KNZ76822.1 - 0.0082 15.7 1.4 0.084 12.3 0.1 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF1848) IRF PF00605.12 KNZ76822.1 - 0.038 13.7 0.3 0.071 12.8 0.1 1.6 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor PIF1 PF05970.9 KNZ76825.1 - 1.7e-51 175.3 0.1 1.9e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ76825.1 - 0.0036 16.9 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KNZ76825.1 - 0.0095 15.4 0.1 0.023 14.2 0.1 1.7 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KNZ76825.1 - 0.01 15.6 0.0 0.024 14.4 0.0 1.6 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KNZ76825.1 - 0.067 13.3 0.1 0.32 11.1 0.1 2.0 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KNZ76825.1 - 0.092 12.1 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KNZ76825.1 - 0.098 12.6 0.0 0.11 12.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Torsin PF06309.6 KNZ76825.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Torsin PhoH PF02562.11 KNZ76825.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.4 2 0 0 2 2 2 0 PhoH-like protein PIF1 PF05970.9 KNZ76826.1 - 9e-34 116.9 0.3 1e-33 116.8 0.2 1.0 1 0 0 1 1 1 1 PIF1-like helicase Pox_I6 PF04595.8 KNZ76826.1 - 0.1 11.3 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus I6-like family DAO PF01266.19 KNZ76828.1 - 3.2e-48 164.4 0.1 4.5e-48 163.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KNZ76828.1 - 3.5e-07 29.6 0.1 5.4e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ76828.1 - 1.6e-05 23.9 0.0 2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KNZ76828.1 - 9.9e-05 22.3 0.0 0.00028 20.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ76828.1 - 0.0016 18.4 0.7 0.0046 16.9 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KNZ76828.1 - 0.0019 18.5 0.3 0.0043 17.4 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KNZ76828.1 - 0.0051 16.4 0.1 0.0097 15.5 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KNZ76828.1 - 0.0084 14.6 0.3 0.012 14.0 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KNZ76828.1 - 0.0095 14.8 0.1 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KNZ76828.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KNZ76828.1 - 0.031 13.3 0.8 0.068 12.2 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 KNZ76828.1 - 0.032 13.1 0.2 0.091 11.6 0.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_10 PF13460.1 KNZ76828.1 - 0.051 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding ERG2_Sigma1R PF04622.7 KNZ76829.1 - 9.6e-88 293.0 0.2 1.1e-87 292.7 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein SSXT PF05030.7 KNZ76830.1 - 0.0066 16.0 0.0 0.0066 16.0 0.0 2.1 2 0 0 2 2 2 1 SSXT protein (N-terminal region) SH3_9 PF14604.1 KNZ76831.1 - 1.9e-14 52.9 0.2 3.1e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KNZ76831.1 - 2.4e-14 52.4 0.1 3.8e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KNZ76831.1 - 2e-13 49.5 0.0 3.1e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Trypan_PARP PF05887.6 KNZ76831.1 - 1.5 8.5 19.6 0.14 11.9 4.7 2.4 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PLU-1 PF08429.6 KNZ76834.1 - 0.069 12.0 4.8 1.8 7.3 0.2 2.7 2 1 1 3 3 3 0 PLU-1-like protein XhlA PF10779.4 KNZ76834.1 - 0.18 11.7 3.2 0.49 10.3 2.2 1.8 1 0 0 1 1 1 0 Haemolysin XhlA DASH_Dad4 PF08650.5 KNZ76834.1 - 0.24 11.3 1.6 9.2 6.2 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad4 Ribosomal_L2_C PF03947.13 KNZ76835.1 - 1.1e-40 138.4 1.4 2e-40 137.6 1.0 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KNZ76835.1 - 3.2e-15 55.8 0.1 6.6e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain tRNA-synt_2 PF00152.15 KNZ76836.1 - 4.9e-56 189.9 0.0 9e-55 185.7 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KNZ76836.1 - 1.3e-08 34.5 0.1 2.8e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KNZ76836.1 - 0.013 14.7 0.3 1.5 7.9 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) BcsB PF03170.8 KNZ76836.1 - 0.082 10.9 0.1 0.12 10.3 0.1 1.1 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit UAA PF08449.6 KNZ76837.1 - 4.8e-57 193.1 9.9 3.6e-56 190.3 6.9 2.2 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 KNZ76837.1 - 0.0027 17.8 4.4 0.0027 17.8 3.1 2.8 3 1 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 KNZ76837.1 - 0.14 11.8 17.4 0.064 12.9 2.4 2.5 3 0 0 3 3 3 0 Triose-phosphate Transporter family DUF202 PF02656.10 KNZ76837.1 - 1.1 9.5 9.4 1.7 8.9 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DUF3185 PF11381.3 KNZ76837.1 - 1.4 8.7 12.6 5 6.9 0.1 3.6 2 2 0 2 2 2 0 Protein of unknown function (DUF3185) Arif-1 PF06770.6 KNZ76837.1 - 7.3 5.8 7.0 0.46 9.8 0.1 2.3 2 1 1 3 3 3 0 Actin-rearrangement-inducing factor (Arif-1) Tetraspannin PF00335.15 KNZ76837.1 - 9.3 5.4 7.6 3 7.0 0.4 2.4 2 1 0 2 2 2 0 Tetraspanin family EAF PF09816.4 KNZ76839.1 - 4e-17 62.1 0.0 1e-16 60.8 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Cu-oxidase PF00394.17 KNZ76840.1 - 3.3e-45 153.8 0.5 1.9e-42 144.8 0.0 3.0 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KNZ76840.1 - 4e-38 130.0 2.3 1.9e-35 121.3 0.3 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KNZ76840.1 - 1.8e-31 108.2 0.7 1.2e-29 102.3 0.0 3.3 4 0 0 4 4 4 1 Multicopper oxidase DUF1323 PF07037.6 KNZ76840.1 - 0.18 12.0 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) Ferritin_2 PF13668.1 KNZ76842.1 - 4.5e-23 81.7 1.1 1.5e-17 63.7 0.1 2.4 2 0 0 2 2 2 2 Ferritin-like domain Transferase PF02458.10 KNZ76843.1 - 0.079 11.3 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Transferase family PRKCSH-like PF12999.2 KNZ76844.1 - 6.5e-49 165.8 1.0 6.5e-49 165.8 0.7 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KNZ76844.1 - 2.6e-24 85.4 0.0 5.7e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KNZ76844.1 - 2.5e-09 37.8 1.0 2.5e-09 37.8 0.7 2.1 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein Peptidase_C6 PF00851.13 KNZ76844.1 - 0.26 9.8 4.6 1.2 7.6 2.2 2.1 2 0 0 2 2 2 0 Helper component proteinase Ldl_recept_a PF00057.13 KNZ76844.1 - 3.8 7.5 15.5 1.8 8.5 1.2 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A V_ATPase_I PF01496.14 KNZ76844.1 - 5.8 4.6 7.5 9.5 3.9 5.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_S25 PF03297.10 KNZ76845.1 - 9.8e-40 134.8 3.3 1.1e-39 134.7 2.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 KNZ76845.1 - 0.036 13.7 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Ftsk gamma domain Nop PF01798.13 KNZ76846.1 - 1.4e-58 196.4 0.5 4e-58 194.9 0.3 1.8 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KNZ76846.1 - 3.7e-27 93.8 0.1 6.6e-27 93.0 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KNZ76846.1 - 1.4e-20 73.1 0.2 3.8e-20 71.8 0.1 1.8 1 0 0 1 1 1 1 NOP5NT (NUC127) domain adh_short PF00106.20 KNZ76847.1 - 0.006 16.5 0.1 3.8 7.4 0.1 2.7 2 1 1 3 3 3 2 short chain dehydrogenase FGGY_C PF02782.11 KNZ76848.1 - 7.4e-46 156.2 0.0 1e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KNZ76848.1 - 1.1e-16 60.9 0.0 2e-15 56.7 0.0 2.7 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KNZ76848.1 - 5e-06 26.0 0.6 0.0076 15.5 0.1 3.0 1 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family CmcH_NodU PF02543.10 KNZ76848.1 - 0.036 13.1 0.0 0.092 11.8 0.0 1.5 1 1 0 1 1 1 0 Carbamoyltransferase UPF0075 PF03702.9 KNZ76848.1 - 0.084 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) FYRC PF05965.9 KNZ76848.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 F/Y rich C-terminus DUF4445 PF14574.1 KNZ76848.1 - 0.13 10.4 0.4 8 4.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4445) Peptidase_S10 PF00450.17 KNZ76849.1 - 7.1e-100 335.0 0.1 9.9e-100 334.5 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KNZ76849.1 - 0.08 12.8 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family p450 PF00067.17 KNZ76850.1 - 7e-58 196.2 0.0 1.6e-57 195.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Ferritin_2 PF13668.1 KNZ76851.1 - 2.9e-34 117.9 0.3 4.5e-34 117.3 0.2 1.3 1 0 0 1 1 1 1 Ferritin-like domain Cyclin PF08613.6 KNZ76854.1 - 1.7e-40 138.8 1.9 7.1e-40 136.8 1.3 2.1 1 1 0 1 1 1 1 Cyclin EBV-NA3 PF05009.7 KNZ76854.1 - 1.9 7.6 4.2 4.1 6.5 2.9 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF605 PF04652.11 KNZ76854.1 - 4.8 6.4 45.5 0.13 11.6 14.2 2.1 2 0 0 2 2 2 0 Vta1 like RVT_3 PF13456.1 KNZ76855.1 - 0.094 12.5 0.1 0.25 11.1 0.1 1.7 1 1 0 1 1 1 0 Reverse transcriptase-like Zn_Tnp_IS1595 PF12760.2 KNZ76856.1 - 0.0013 18.4 1.9 0.0041 16.9 1.3 1.9 1 1 0 1 1 1 1 Transposase zinc-ribbon domain zf-RVT PF13966.1 KNZ76856.1 - 0.069 13.4 0.4 0.14 12.4 0.3 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase NOB1_Zn_bind PF08772.6 KNZ76856.1 - 0.07 12.9 0.1 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Ceramidase_alk PF04734.8 KNZ76857.1 - 2.9e-105 352.6 1.9 6.4e-102 341.5 0.3 3.8 1 1 1 2 2 2 2 Neutral/alkaline non-lysosomal ceramidase Abhydrolase_4 PF08386.5 KNZ76858.1 - 9.3e-20 70.4 0.0 1.7e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KNZ76858.1 - 8.9e-16 58.1 0.0 3.3e-15 56.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KNZ76858.1 - 0.00016 21.6 0.0 0.00039 20.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cyclin_N PF00134.18 KNZ76859.1 - 1.8e-10 40.4 0.1 3.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ldh_1_C PF02866.13 KNZ76860.1 - 2.9e-42 144.3 0.0 4.2e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KNZ76860.1 - 8e-31 106.7 0.2 1.6e-30 105.7 0.1 1.5 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.15 KNZ76860.1 - 0.0062 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KNZ76860.1 - 0.017 15.4 0.4 0.051 13.8 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KNZ76860.1 - 0.017 13.8 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CbiG_N PF11760.3 KNZ76860.1 - 0.039 13.6 1.1 0.96 9.1 0.0 2.5 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal PMT PF02366.13 KNZ76861.1 - 2.1e-78 263.0 16.3 4.6e-78 261.9 11.3 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KNZ76861.1 - 7.4e-46 156.0 0.3 1.5e-45 155.0 0.2 1.5 1 0 0 1 1 1 1 MIR domain DUF1240 PF06836.7 KNZ76861.1 - 0.3 11.3 4.4 7.2 6.9 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1240) DUF21 PF01595.15 KNZ76862.1 - 1.9e-15 56.6 3.9 3e-15 56.0 1.1 2.2 2 1 0 2 2 2 1 Domain of unknown function DUF21 Abhydrolase_6 PF12697.2 KNZ76863.1 - 0.009 15.9 0.0 0.076 12.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ76863.1 - 0.041 13.4 0.1 0.79 9.2 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold SDA1 PF05285.7 KNZ76865.1 - 0.056 12.7 1.1 0.12 11.6 0.8 1.4 1 0 0 1 1 1 0 SDA1 Abhydrolase_6 PF12697.2 KNZ76866.1 - 7e-29 101.3 2.1 1.1e-28 100.7 1.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ76866.1 - 3.3e-19 69.3 1.6 1e-18 67.7 1.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ76866.1 - 3e-08 33.5 0.0 1.2e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KNZ76866.1 - 0.029 14.2 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Ndr PF03096.9 KNZ76866.1 - 0.072 11.5 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Ndr family Maf PF02545.9 KNZ76867.1 - 3e-40 137.4 0.0 4.3e-24 84.7 0.0 2.0 2 0 0 2 2 2 2 Maf-like protein DUF4012 PF13196.1 KNZ76867.1 - 0.05 13.7 0.6 0.087 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4012) TPR_6 PF13174.1 KNZ76867.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA PF00004.24 KNZ76869.1 - 1.9e-46 157.5 0.0 3e-41 140.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNZ76869.1 - 2.7e-07 30.7 0.3 2.6e-06 27.5 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 KNZ76869.1 - 2.2e-06 27.2 0.0 1.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 KNZ76869.1 - 2.3e-05 24.4 0.0 5.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KNZ76869.1 - 7.2e-05 22.9 0.9 0.0066 16.5 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KNZ76869.1 - 0.00017 21.2 0.2 0.0033 17.1 0.0 2.9 3 0 0 3 3 3 1 Part of AAA domain AAA_5 PF07728.9 KNZ76869.1 - 0.002 17.8 0.0 0.013 15.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KNZ76869.1 - 0.0039 17.9 0.6 0.032 15.0 0.0 3.0 3 0 0 3 3 1 1 AAA domain AAA_25 PF13481.1 KNZ76869.1 - 0.004 16.5 0.0 0.054 12.9 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 KNZ76869.1 - 0.015 15.1 0.0 0.015 15.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.1 KNZ76869.1 - 0.019 14.9 1.3 0.076 12.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KNZ76869.1 - 0.044 13.0 0.0 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 KNZ76869.1 - 0.044 13.2 0.0 1.4 8.3 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_18 PF13238.1 KNZ76869.1 - 0.045 14.0 0.0 0.045 14.0 0.0 2.8 4 0 0 4 4 1 0 AAA domain AAA_30 PF13604.1 KNZ76869.1 - 0.051 13.1 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KNZ76869.1 - 0.058 12.5 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KNZ76869.1 - 0.067 11.9 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus RuvB_N PF05496.7 KNZ76869.1 - 0.098 11.6 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KNZ76869.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF3394 PF11874.3 KNZ76869.1 - 0.13 11.7 0.0 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) Sigma54_activ_2 PF14532.1 KNZ76869.1 - 0.19 11.7 0.0 1 9.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KNZ76869.1 - 0.25 10.1 0.0 0.44 9.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CRAL_TRIO_2 PF13716.1 KNZ76871.1 - 2.1e-31 108.8 0.1 3.5e-31 108.1 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 KNZ76871.1 - 1.8e-26 92.5 0.0 2.7e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.15 KNZ76871.1 - 0.00037 20.0 0.1 0.00073 19.0 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Sigma54_activat PF00158.21 KNZ76871.1 - 0.069 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Suf PF05843.9 KNZ76872.1 - 8.6e-72 242.2 0.0 2.1e-69 234.3 0.0 3.2 4 0 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KNZ76872.1 - 6.2e-12 45.0 3.5 0.001 19.4 0.0 6.4 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ76872.1 - 3.8e-10 40.1 6.7 0.0022 18.6 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ76872.1 - 3e-06 27.4 6.5 0.015 15.6 0.3 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat FTCD_C PF04961.7 KNZ76872.1 - 0.018 14.4 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase TPR_6 PF13174.1 KNZ76872.1 - 0.022 15.1 3.5 3.2 8.4 0.0 5.4 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ76872.1 - 0.029 14.0 5.4 0.045 13.4 0.2 2.8 3 0 0 3 3 3 0 TPR repeat Mad3_BUB1_I PF08311.7 KNZ76872.1 - 0.28 10.9 6.2 1.5 8.6 0.1 3.6 3 1 1 4 4 4 0 Mad3/BUB1 homology region 1 NRDE-2 PF08424.5 KNZ76872.1 - 6.1 5.6 8.4 4.6 6.0 0.1 3.6 2 1 1 3 3 3 0 NRDE-2, necessary for RNA interference Peptidase_S10 PF00450.17 KNZ76874.1 - 4.4e-80 269.8 0.0 5.4e-80 269.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase RRM_1 PF00076.17 KNZ76875.1 - 3.2e-33 113.1 0.4 3.5e-16 58.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ76875.1 - 6.5e-27 93.3 0.3 1.4e-14 53.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ76875.1 - 5.9e-11 42.0 0.2 1e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KNZ76875.1 - 0.16 11.7 0.0 16 5.3 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif SNO PF01174.14 KNZ76877.1 - 3e-49 167.1 0.0 6e-39 133.6 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KNZ76877.1 - 5.3e-08 32.6 0.0 6.9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.12 KNZ76877.1 - 5.3e-06 26.2 0.0 7.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DUF4066 PF13278.1 KNZ76877.1 - 1.9e-05 24.0 0.0 6.4e-05 22.2 0.1 1.7 2 0 0 2 2 2 1 Putative amidotransferase GATase PF00117.23 KNZ76877.1 - 0.00017 21.1 0.0 0.0003 20.3 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 KNZ76877.1 - 0.015 14.7 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_S10 PF00450.17 KNZ76878.1 - 2e-69 234.7 0.0 3.5e-69 233.9 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_85 PF03644.8 KNZ76879.1 - 4e-70 236.4 0.0 6.6e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 An_peroxidase PF03098.10 KNZ76880.1 - 7.3e-81 272.1 0.0 1.4e-78 264.6 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KNZ76880.1 - 2e-05 23.3 0.0 3.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 WEMBL PF05701.6 KNZ76881.1 - 0.047 12.1 2.5 0.056 11.9 1.7 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light An_peroxidase PF03098.10 KNZ76883.1 - 4.8e-72 243.0 0.0 1.4e-69 234.9 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KNZ76883.1 - 1.2e-05 24.1 0.1 5.9e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 DUF948 PF06103.6 KNZ76884.1 - 0.37 10.6 2.3 1.1 9.2 1.6 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2530 PF10745.4 KNZ76884.1 - 0.44 10.5 5.3 0.68 9.9 2.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2530) Pkinase_Tyr PF07714.12 KNZ76885.1 - 4.4e-32 111.1 0.0 1.9e-31 109.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ76885.1 - 1.9e-31 109.1 0.0 3.9e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF4543 PF15076.1 KNZ76885.1 - 0.096 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) Kinase-like PF14531.1 KNZ76885.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 KNZ76886.1 - 1.6e-10 40.5 0.0 2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ76886.1 - 3.1e-10 39.5 0.0 3.9e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ76888.1 - 3.7e-18 65.6 0.0 4.3e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ76888.1 - 4.1e-14 52.2 0.0 4.6e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ76888.1 - 0.0015 17.5 0.0 0.0018 17.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KNZ76888.1 - 0.017 14.5 0.1 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KNZ76888.1 - 0.041 12.9 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_Helicase PF02689.9 KNZ76889.1 - 1.8e-05 22.7 0.0 1.9e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 Helicase Pkinase_Tyr PF07714.12 KNZ76890.1 - 6.2e-37 127.0 0.0 9.1e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ76890.1 - 4.9e-34 117.6 0.0 7.9e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KNZ76890.1 - 0.00072 18.6 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KNZ76890.1 - 0.0035 16.7 0.0 0.038 13.3 0.0 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KNZ76890.1 - 0.004 16.9 0.4 0.05 13.3 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Endonuc-MspI PF09208.5 KNZ76890.1 - 0.069 12.2 0.0 0.32 10.0 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease MspI EcKinase PF02958.15 KNZ76890.1 - 0.19 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.20 KNZ76891.1 - 3e-33 115.0 0.0 3.4e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ76891.1 - 5.1e-29 101.1 0.0 7.7e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KNZ76891.1 - 0.002 17.2 0.0 0.0036 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KNZ76892.1 - 2.6e-36 125.1 0.0 5.3e-36 124.1 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ76892.1 - 8.9e-33 113.4 0.0 1.6e-32 112.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KNZ76892.1 - 0.002 17.5 0.0 0.016 14.5 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KNZ76892.1 - 0.021 13.9 0.0 0.046 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pertus-S4-tox PF09275.5 KNZ76893.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin S4 subunit Astro_capsid PF03115.9 KNZ76894.1 - 0.051 11.8 0.5 0.063 11.5 0.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Nop14 PF04147.7 KNZ76894.1 - 0.72 7.6 16.5 1.3 6.8 11.4 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 KNZ76894.1 - 1 8.5 13.9 1.5 8.0 9.6 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 KNZ76894.1 - 1.1 7.2 8.5 1.5 6.7 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 KNZ76894.1 - 2.1 7.3 17.7 3.1 6.7 12.3 1.2 1 0 0 1 1 1 0 BUD22 Sigma70_r3 PF04539.11 KNZ76895.1 - 1.7e-05 24.5 0.0 5.2e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 region 3 adh_short PF00106.20 KNZ76896.1 - 8.6e-24 84.3 0.1 1.1e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ76896.1 - 2.5e-08 34.0 0.0 3.2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ76896.1 - 1.9e-07 30.8 0.0 2.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KNZ76896.1 - 1.7e-05 24.3 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KNZ76896.1 - 3.6e-05 23.0 0.0 4.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KNZ76896.1 - 0.00032 20.7 0.1 0.00054 20.0 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KNZ76896.1 - 0.00077 18.4 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 KNZ76896.1 - 0.0029 16.8 0.1 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Chromo PF00385.19 KNZ76902.1 - 1.9e-17 62.6 0.1 2.2e-17 62.4 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KNZ76902.1 - 0.13 12.2 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Pyr_redox_3 PF13738.1 KNZ76903.1 - 2.1e-17 63.8 0.0 1.3e-15 57.9 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KNZ76903.1 - 1.4e-15 56.5 0.0 2.8e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KNZ76903.1 - 1.6e-12 46.9 0.0 1.2e-08 34.2 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KNZ76903.1 - 7.6e-10 39.0 0.0 0.0037 17.1 0.0 3.2 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KNZ76903.1 - 2.1e-06 28.0 0.0 0.0069 16.7 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ76903.1 - 1.7e-05 24.7 0.0 0.048 13.6 0.0 3.4 4 0 0 4 4 3 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KNZ76903.1 - 0.00013 21.1 0.0 0.25 10.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 KNZ76903.1 - 0.0024 16.9 0.0 1 8.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_Gly3P_dh_N PF01210.18 KNZ76903.1 - 0.0031 17.2 0.0 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 KNZ76903.1 - 0.0036 17.4 0.0 0.54 10.3 0.0 2.6 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KNZ76903.1 - 0.0075 15.4 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KNZ76903.1 - 0.011 15.3 0.0 0.038 13.6 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KNZ76903.1 - 0.028 13.2 0.0 0.41 9.4 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A DAO PF01266.19 KNZ76903.1 - 0.041 12.7 0.0 14 4.4 0.0 3.2 4 0 0 4 4 4 0 FAD dependent oxidoreductase CPSase_L_chain PF00289.17 KNZ76903.1 - 0.044 13.8 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Lycopene_cycl PF05834.7 KNZ76903.1 - 0.048 12.5 0.0 2.9 6.6 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Me-amine-dh_L PF02975.9 KNZ76903.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain NAD_binding_9 PF13454.1 KNZ76903.1 - 0.09 12.5 0.3 6.6 6.4 0.0 3.4 3 1 1 4 4 4 0 FAD-NAD(P)-binding ApbA PF02558.11 KNZ76903.1 - 0.15 11.4 0.0 1.2 8.5 0.0 2.4 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Asp_protease_2 PF13650.1 KNZ76904.1 - 0.0024 18.3 0.0 0.016 15.7 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease AMP-binding PF00501.23 KNZ76905.1 - 1.4e-10 40.1 0.1 1.8e-10 39.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NMD3 PF04981.8 KNZ76906.1 - 2.2e-25 89.1 5.2 1.3e-18 66.9 0.7 2.2 1 1 1 2 2 2 2 NMD3 family DUF35_N PF12172.3 KNZ76906.1 - 9.6 6.2 7.7 22 5.1 0.5 3.0 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TPR_14 PF13428.1 KNZ76907.1 - 0.038 14.6 0.0 5.5 7.9 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Nramp PF01566.13 KNZ76908.1 - 1.9e-93 313.1 19.4 2.5e-93 312.7 13.4 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF4501 PF14946.1 KNZ76908.1 - 0.59 9.6 4.3 1.6 8.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) GCD14_N PF14801.1 KNZ76909.1 - 0.25 10.9 1.4 0.3 10.6 0.3 1.6 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term Sugar_tr PF00083.19 KNZ76910.1 - 1e-28 100.1 34.1 1.2e-19 70.2 6.9 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KNZ76910.1 - 1.5e-14 53.5 50.2 6e-11 41.6 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KNZ76910.1 - 0.0018 16.7 1.9 0.0018 16.7 1.3 3.6 2 2 1 3 3 3 2 MFS/sugar transport protein DUF4179 PF13786.1 KNZ76910.1 - 0.12 12.6 2.7 0.34 11.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) DUF2235 PF09994.4 KNZ76912.1 - 3.1e-79 266.2 0.0 4.2e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KNZ76912.1 - 0.023 14.4 0.0 0.045 13.4 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.6 KNZ76912.1 - 0.12 12.0 0.0 0.86 9.2 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal GST_C_2 PF13410.1 KNZ76914.1 - 0.049 13.5 0.1 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 KNZ76915.1 - 3.3 7.9 11.7 0.74 10.0 5.6 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain ECH_C PF13766.1 KNZ76916.1 - 0.058 13.5 0.2 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region GvpH PF05455.6 KNZ76916.1 - 0.12 12.0 1.1 0.48 10.0 0.0 2.3 2 1 1 3 3 3 0 GvpH RVP_2 PF08284.6 KNZ76917.1 - 0.0029 17.5 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KNZ76917.1 - 0.0065 16.2 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ76917.1 - 0.018 15.5 0.0 0.026 15.0 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Keratin_assoc PF09775.4 KNZ76917.1 - 0.12 11.9 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Ubiq_cyt_C_chap PF03981.7 KNZ76925.1 - 6.5e-27 94.1 0.0 1.7e-13 50.5 0.0 3.1 2 1 0 2 2 2 2 Ubiquinol-cytochrome C chaperone Aminotran_1_2 PF00155.16 KNZ76928.1 - 3.8e-51 174.1 0.0 4.3e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Zn_Tnp_IS1595 PF12760.2 KNZ76929.1 - 0.00026 20.7 1.6 0.00084 19.0 1.1 1.9 1 1 0 1 1 1 1 Transposase zinc-ribbon domain zf-RVT PF13966.1 KNZ76929.1 - 0.00059 20.1 0.1 0.00092 19.4 0.1 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zinc_ribbon_2 PF13240.1 KNZ76929.1 - 0.046 13.2 0.4 0.09 12.2 0.3 1.5 1 1 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KNZ76929.1 - 0.052 12.7 0.5 0.1 11.8 0.4 1.5 1 1 0 1 1 1 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 KNZ76929.1 - 0.16 11.6 0.2 0.33 10.6 0.1 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-RING_3 PF14369.1 KNZ76929.1 - 0.72 9.8 3.4 0.75 9.8 0.5 2.1 1 1 1 2 2 2 0 zinc-finger WD40 PF00400.27 KNZ76930.1 - 1.7e-68 224.1 33.0 4.7e-16 57.9 0.8 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KNZ76930.1 - 7.8e-07 28.4 0.0 3.8 7.0 0.0 5.0 5 0 0 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 KNZ76930.1 - 0.065 12.9 0.6 2.5 7.8 0.1 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat SHMT PF00464.14 KNZ76931.1 - 1e-166 554.2 0.0 1.2e-166 554.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase HIG_1_N PF04588.8 KNZ76932.1 - 2.8e-19 68.6 0.8 4e-19 68.0 0.6 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF883 PF05957.8 KNZ76932.1 - 0.53 10.7 3.4 1.6 9.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Mis12 PF05859.7 KNZ76933.1 - 5.9e-22 78.0 0.1 1e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein Alba PF01918.16 KNZ76934.1 - 0.074 12.6 0.0 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 Alba Cullin PF00888.17 KNZ76935.1 - 5.5e-41 140.7 0.0 1.4e-40 139.4 0.0 1.6 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 KNZ76935.1 - 3.6e-10 39.9 0.1 1.2e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 AdoHcyase PF05221.12 KNZ76936.1 - 3.5e-136 452.4 0.0 4.2e-136 452.1 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KNZ76936.1 - 1.8e-85 284.7 0.2 2.8e-85 284.1 0.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KNZ76936.1 - 1.3e-08 34.2 0.0 2.7e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KNZ76936.1 - 4.9e-05 22.7 0.0 8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KNZ76936.1 - 0.0011 18.9 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 KNZ76936.1 - 0.029 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase F420_oxidored PF03807.12 KNZ76936.1 - 0.054 13.9 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TMEM107 PF14995.1 KNZ76936.1 - 0.063 13.4 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein Mitochondr_Som1 PF11093.3 KNZ76937.1 - 0.0049 16.6 0.4 0.011 15.5 0.2 1.6 2 0 0 2 2 2 1 Mitochondrial export protein Som1 Tht1 PF04163.7 KNZ76939.1 - 1.6e-10 40.0 2.7 1.6e-10 40.0 1.8 2.4 1 1 1 2 2 2 1 Tht1-like nuclear fusion protein Abhydrolase_1 PF00561.15 KNZ76940.1 - 2.4e-34 118.9 0.0 4.5e-34 118.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KNZ76940.1 - 2.6e-11 43.8 1.4 6.7e-11 42.5 0.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KNZ76940.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein RRM_1 PF00076.17 KNZ76941.1 - 3e-08 33.1 0.0 6.9e-07 28.8 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 KNZ76941.1 - 1.2e-06 28.4 7.5 3.1e-06 27.0 5.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ76941.1 - 6.9e-06 25.6 6.8 1.7e-05 24.4 4.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KNZ76941.1 - 1e-05 25.3 6.8 2.5e-05 24.0 4.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KNZ76941.1 - 1.7e-05 24.5 7.3 5.2e-05 22.9 5.1 1.9 1 0 0 1 1 1 1 Ring finger domain RRM_6 PF14259.1 KNZ76941.1 - 9.4e-05 22.3 0.0 0.0039 17.1 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 KNZ76941.1 - 0.00036 20.1 5.3 0.00093 18.8 3.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KNZ76941.1 - 0.00042 19.9 4.3 0.00093 18.8 3.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger IBR PF01485.16 KNZ76941.1 - 0.0016 18.3 1.9 0.75 9.7 0.0 2.8 2 0 0 2 2 2 2 IBR domain RRM_5 PF13893.1 KNZ76941.1 - 0.0035 17.1 0.0 2.9 7.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_5 PF14634.1 KNZ76941.1 - 0.0045 16.6 6.6 0.011 15.4 4.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain TPMT PF05724.6 KNZ76943.1 - 2.1e-35 122.1 0.0 2.9e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 KNZ76943.1 - 1.1e-12 47.8 0.0 1.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ76943.1 - 2.4e-09 37.7 0.0 3.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ76943.1 - 3.7e-08 33.7 0.0 5.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ76943.1 - 3e-07 30.4 0.0 5.8e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ76943.1 - 9.7e-07 29.1 0.0 1.4e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KNZ76943.1 - 0.0012 18.0 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 KNZ76943.1 - 0.018 14.5 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 KNZ76943.1 - 0.019 14.5 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.8 KNZ76943.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pribosyltran PF00156.22 KNZ76945.1 - 1.8e-16 59.9 0.4 2.8e-16 59.3 0.3 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KNZ76945.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase La PF05383.12 KNZ76946.1 - 2.1e-17 62.6 0.0 4e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 La domain Pmp3 PF01679.12 KNZ76947.1 - 1.2e-16 60.1 5.2 1.5e-16 59.8 3.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Statherin PF03875.8 KNZ76947.1 - 9.8 6.1 9.8 15 5.5 6.8 1.3 1 0 0 1 1 1 0 Statherin Rsa3 PF14615.1 KNZ76948.1 - 0.00016 20.8 0.0 0.00028 20.0 0.0 1.3 1 0 0 1 1 1 1 Ribosome-assembly protein 3 GTSE1_N PF15259.1 KNZ76948.1 - 0.066 13.1 1.7 0.081 12.8 1.2 1.2 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 Peroxin-13_N PF04088.8 KNZ76950.1 - 1.4e-45 155.1 0.0 2.1e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 KNZ76950.1 - 3e-10 39.4 0.0 5.6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KNZ76950.1 - 1.2e-09 37.3 1.8 0.0016 17.8 1.8 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KNZ76950.1 - 2.7e-08 33.2 0.4 5.8e-08 32.1 0.3 1.6 1 1 0 1 1 1 1 Variant SH3 domain Cytochrom_B_N PF00033.14 KNZ76950.1 - 0.0044 16.4 0.1 0.0072 15.6 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Flu_M1 PF00598.14 KNZ76951.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) Kelch_6 PF13964.1 KNZ76953.1 - 0.0057 16.7 0.2 1.1 9.5 0.1 3.2 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 KNZ76953.1 - 2.7 8.2 5.9 10 6.4 0.0 3.7 3 1 1 4 4 4 0 Galactose oxidase, central domain FA_desaturase PF00487.19 KNZ76954.1 - 1.6e-25 90.0 18.7 2.7e-25 89.3 12.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KNZ76954.1 - 5.7e-07 29.6 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF3433 PF11915.3 KNZ76955.1 - 2.3e-20 72.5 3.3 2.3e-20 72.5 2.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) MutS_V PF00488.16 KNZ76956.1 - 2.1e-85 285.8 0.0 3.4e-85 285.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KNZ76956.1 - 3.2e-25 89.1 0.7 8.9e-25 87.6 0.1 2.0 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.13 KNZ76956.1 - 7.9e-19 67.6 1.4 7.9e-19 67.6 0.9 2.3 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 KNZ76956.1 - 2.2e-14 53.7 0.2 2e-13 50.5 0.0 2.7 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.15 KNZ76956.1 - 7.7e-07 29.1 0.0 2.1e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 MutS domain I Nol1_Nop2_Fmu PF01189.12 KNZ76958.1 - 5e-31 108.1 0.0 1e-28 100.5 0.0 2.5 1 1 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KNZ76958.1 - 0.00073 19.5 0.0 0.002 18.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KNZ76958.1 - 0.014 15.3 0.0 0.044 13.7 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase Saccharop_dh PF03435.13 KNZ76959.1 - 2.1e-110 369.3 0.2 5.1e-110 368.0 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 KNZ76959.1 - 1.3e-89 299.4 0.0 3e-89 298.1 0.0 1.6 1 0 0 1 1 1 1 Spermine/spermidine synthase Shikimate_DH PF01488.15 KNZ76959.1 - 2.9e-08 33.8 0.2 1.7e-06 28.1 0.1 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KNZ76959.1 - 0.0017 18.4 0.3 0.0036 17.3 0.2 1.5 1 0 0 1 1 1 1 NADH(P)-binding Methyltransf_18 PF12847.2 KNZ76959.1 - 0.011 16.3 0.0 0.036 14.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Semialdhyde_dh PF01118.19 KNZ76959.1 - 0.072 13.4 0.4 0.29 11.4 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DREV PF05219.7 KNZ76959.1 - 0.19 10.5 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase SNF2_N PF00176.18 KNZ76960.1 - 2.2e-69 233.5 0.8 3.5e-69 232.8 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 KNZ76960.1 - 4.7e-10 39.1 5.9 1.1e-09 38.0 4.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KNZ76960.1 - 4.5e-09 35.8 6.3 9.3e-09 34.8 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ76960.1 - 6.2e-09 35.3 5.2 1.4e-08 34.2 3.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ76960.1 - 7.7e-09 35.4 6.2 1.8e-08 34.2 4.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 KNZ76960.1 - 1.5e-07 31.1 0.3 5.7e-07 29.3 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.1 KNZ76960.1 - 3.4e-07 29.8 2.1 8e-07 28.6 1.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KNZ76960.1 - 8.2e-07 28.6 4.0 1.8e-06 27.5 2.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KNZ76960.1 - 1.7e-05 24.6 4.6 4.4e-05 23.2 3.2 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KNZ76960.1 - 0.027 14.5 0.7 0.077 13.1 0.5 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 KNZ76960.1 - 0.046 13.4 1.1 0.17 11.7 0.8 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 KNZ76960.1 - 0.19 11.2 3.6 0.47 10.0 2.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KNZ76960.1 - 0.61 9.7 4.9 1.7 8.2 3.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain adh_short PF00106.20 KNZ76961.1 - 1.1e-11 44.9 0.4 2.5e-11 43.7 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ76961.1 - 3.6e-06 26.7 0.1 5.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KNZ76961.1 - 0.0013 18.8 0.5 0.003 17.6 0.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KNZ76961.1 - 0.03 14.0 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase IclR PF01614.13 KNZ76961.1 - 0.099 12.3 0.0 14 5.3 0.0 2.8 3 0 0 3 3 3 0 Bacterial transcriptional regulator Shikimate_DH PF01488.15 KNZ76961.1 - 0.1 12.7 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UBN2_3 PF14244.1 KNZ76963.1 - 0.05 13.1 0.0 0.063 12.8 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF2034 PF10356.4 KNZ76964.1 - 4.1e-31 107.5 0.3 2.4e-15 56.1 0.0 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KNZ76964.1 - 9.5e-08 31.8 0.0 3e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Restriction endonuclease G-alpha PF00503.15 KNZ76965.1 - 2.1e-96 323.0 0.5 2.4e-96 322.7 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KNZ76965.1 - 1.5e-11 43.8 1.2 4.8e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family PRANC PF09372.5 KNZ76966.1 - 0.00081 19.3 0.0 0.025 14.5 0.0 2.4 2 0 0 2 2 2 1 PRANC domain Peroxidase_2 PF01328.12 KNZ76967.1 - 5e-14 51.7 0.1 3.1e-13 49.0 0.1 1.9 1 1 0 1 1 1 1 Peroxidase, family 2 RdRP PF05183.7 KNZ76968.1 - 3.4e-87 293.4 0.0 5.5e-60 203.6 0.0 2.1 1 1 1 2 2 2 2 RNA dependent RNA polymerase zf-C3HC4_3 PF13920.1 KNZ76969.1 - 5.8e-07 29.0 4.7 1e-06 28.3 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ76969.1 - 1.6e-06 27.7 3.3 2.8e-06 26.9 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KNZ76969.1 - 0.00023 20.7 4.7 0.00047 19.7 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ76969.1 - 0.00057 19.6 5.2 0.0014 18.3 3.6 1.7 1 0 0 1 1 1 1 Ring finger domain RRM_6 PF14259.1 KNZ76969.1 - 0.0033 17.3 0.0 0.0076 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 KNZ76969.1 - 0.0084 16.1 6.1 0.019 15.0 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 KNZ76969.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_4 PF14570.1 KNZ76969.1 - 0.96 9.0 2.8 1.8 8.2 2.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KNZ76969.1 - 1.5 8.7 5.4 3.4 7.6 3.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pkinase PF00069.20 KNZ76970.1 - 5.5e-20 71.6 0.0 7.2e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ76970.1 - 2.4e-18 66.1 0.0 3.2e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ76970.1 - 0.0023 17.6 0.1 0.0045 16.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KNZ76970.1 - 0.0063 15.5 0.0 0.0086 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like WaaY PF06176.6 KNZ76970.1 - 0.016 14.4 0.2 0.04 13.1 0.0 1.6 1 1 1 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) YukC PF10140.4 KNZ76970.1 - 0.029 12.9 0.1 0.052 12.1 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Polysacc_deac_2 PF04748.8 KNZ76970.1 - 0.052 12.5 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Toxin_49 PF15529.1 KNZ76971.1 - 4.7e-09 36.0 22.8 0.0001 22.1 6.0 2.4 2 0 0 2 2 2 2 Putative toxin 49 FliC PF12445.3 KNZ76971.1 - 0.25 11.4 1.3 8 6.6 0.1 2.1 2 0 0 2 2 2 0 Flagellin protein BTB PF00651.26 KNZ76972.1 - 1.2e-07 31.6 0.2 2.3e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain GBP_C PF02841.9 KNZ76975.1 - 0.06 12.5 24.8 0.33 10.1 8.3 2.4 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain THOC7 PF05615.8 KNZ76975.1 - 1.2 9.4 30.0 2.2 8.5 9.4 2.6 1 1 1 2 2 2 0 Tho complex subunit 7 GrpE PF01025.14 KNZ76975.1 - 1.3 8.5 20.4 1.7 8.1 7.0 2.8 2 0 0 2 2 2 0 GrpE Macoilin PF09726.4 KNZ76975.1 - 2.4 6.3 33.1 53 1.8 22.4 2.1 1 1 0 1 1 1 0 Transmembrane protein MDMPI_N PF11716.3 KNZ76975.1 - 8.7 6.7 8.1 23 5.4 1.0 2.7 3 0 0 3 3 3 0 Mycothiol maleylpyruvate isomerase N-terminal domain bZIP_1 PF00170.16 KNZ76977.1 - 1.4e-06 28.1 5.0 1.4e-06 28.1 3.5 2.6 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KNZ76977.1 - 0.00022 20.9 3.6 0.00022 20.9 2.5 4.7 4 1 1 5 5 5 2 Basic region leucine zipper Chromo PF00385.19 KNZ76983.1 - 6.8e-16 57.6 0.2 8.4e-16 57.4 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KNZ76983.1 - 0.072 13.0 0.1 0.097 12.5 0.0 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Epimerase_Csub PF13950.1 KNZ76983.1 - 0.2 11.6 0.9 0.33 10.9 0.6 1.3 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Homeobox PF00046.24 KNZ76984.1 - 3.7e-16 58.4 0.5 1.2e-15 56.8 0.3 1.9 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KNZ76984.1 - 1.7e-06 27.5 0.2 4.3e-06 26.3 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain N6_Mtase PF02384.11 KNZ76984.1 - 0.032 13.3 0.0 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 N-6 DNA Methylase Poxvirus_B22R_C PF13168.1 KNZ76984.1 - 0.043 13.0 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal Mating_C PF12737.2 KNZ76985.1 - 2.4e-25 89.3 17.1 2.4e-25 89.3 11.9 1.6 2 0 0 2 2 2 1 C-terminal domain of homeodomain 1 Homeobox_KN PF05920.6 KNZ76985.1 - 3.2e-17 61.9 0.1 1.5e-16 59.7 0.1 2.3 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KNZ76985.1 - 0.013 15.1 0.1 0.066 12.8 0.0 2.3 2 0 0 2 2 2 0 Homeobox domain Peptidase_M3 PF01432.15 KNZ76986.1 - 6.3e-135 450.7 0.0 7.5e-135 450.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 KNZ76986.1 - 0.053 12.8 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_M91 PF14891.1 KNZ76986.1 - 0.067 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Effector protein DUF1754 PF08555.5 KNZ76988.1 - 9.5e-14 51.7 11.0 1.6e-13 51.0 7.6 1.4 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) SR-25 PF10500.4 KNZ76988.1 - 0.0019 17.7 15.8 0.0024 17.3 11.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein ELL PF10390.4 KNZ76988.1 - 0.074 12.2 8.2 0.098 11.8 5.7 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Menin PF05053.8 KNZ76988.1 - 0.077 11.1 2.2 0.087 10.9 1.5 1.1 1 0 0 1 1 1 0 Menin NinG PF05766.7 KNZ76988.1 - 0.082 12.6 5.9 0.19 11.4 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein DUF4662 PF15578.1 KNZ76988.1 - 2 7.9 8.3 2.7 7.4 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) U79_P34 PF03064.11 KNZ76988.1 - 4.6 6.6 10.8 6.2 6.2 7.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1751 PF08551.5 KNZ76989.1 - 1e-27 96.3 6.0 1.9e-27 95.4 4.2 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DER1 PF04511.10 KNZ76989.1 - 0.00025 20.5 11.8 0.00039 19.9 8.2 1.3 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 KNZ76989.1 - 0.00076 19.5 11.3 0.00097 19.1 7.2 1.5 1 1 0 1 1 1 1 Rhomboid family Vps51 PF08700.6 KNZ76990.1 - 4.4e-13 48.8 0.9 2.1e-12 46.7 0.6 2.2 1 0 0 1 1 1 1 Vps51/Vps67 SecE PF00584.15 KNZ76991.1 - 5.3e-11 41.9 0.0 7.2e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Mit_proteolip PF08039.6 KNZ76991.1 - 0.048 13.6 0.4 0.14 12.2 0.1 1.9 1 1 1 2 2 2 0 Mitochondrial proteolipid PPR_2 PF13041.1 KNZ76992.1 - 1e-16 60.6 0.7 0.012 15.5 0.0 8.5 8 1 1 9 9 9 5 PPR repeat family PPR_1 PF12854.2 KNZ76992.1 - 6.2e-07 28.7 2.2 0.76 9.3 0.0 6.8 8 1 0 8 8 8 2 PPR repeat PPR_3 PF13812.1 KNZ76992.1 - 6.7e-06 25.9 0.4 6.4 7.3 0.0 6.8 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 KNZ76992.1 - 1.6e-05 24.5 7.7 0.19 11.7 0.0 6.2 7 0 0 7 7 7 2 PPR repeat CobN-Mg_chel PF02514.11 KNZ76992.1 - 0.051 10.9 0.0 0.07 10.5 0.0 1.2 1 0 0 1 1 1 0 CobN/Magnesium Chelatase RPM2 PF08579.6 KNZ76992.1 - 0.076 13.1 0.0 9.6 6.3 0.0 3.6 3 1 0 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) BTAD PF03704.12 KNZ76992.1 - 0.15 12.3 2.0 4.4 7.6 0.0 3.7 5 0 0 5 5 5 0 Bacterial transcriptional activator domain GDC-P PF02347.11 KNZ76993.1 - 5.5e-177 588.7 0.0 2.2e-165 550.4 0.0 3.4 3 1 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KNZ76993.1 - 0.00036 19.7 0.0 0.00078 18.6 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KNZ76993.1 - 0.00037 19.3 0.0 0.00079 18.2 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V DUF1741 PF08427.5 KNZ76994.1 - 1.3e-18 67.3 0.1 1.3e-18 67.3 0.1 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1741) Nop52 PF05997.7 KNZ76995.1 - 1e-66 224.4 0.0 1.3e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.1 KNZ76995.1 - 0.0037 16.5 0.0 0.0056 15.9 0.0 1.3 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II Transthyretin PF00576.16 KNZ76996.1 - 2.1e-31 108.1 0.0 4.7e-31 106.9 0.0 1.5 1 1 0 1 1 1 1 HIUase/Transthyretin family MG1 PF11974.3 KNZ76996.1 - 0.14 12.6 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain UQ_con PF00179.21 KNZ76997.1 - 2.2e-39 134.0 0.0 2.8e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KNZ76997.1 - 0.027 14.1 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain 2OG-FeII_Oxy PF03171.15 KNZ76998.1 - 0.00066 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KNZ76998.1 - 0.018 15.5 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Chorismate_bind PF00425.13 KNZ76999.1 - 6.7e-62 209.1 0.0 9e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 KNZ76999.1 - 3.7e-31 108.0 0.0 5.3e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KNZ76999.1 - 2.1e-16 60.2 0.0 8.2e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KNZ76999.1 - 0.00027 20.4 0.4 0.0014 18.1 0.3 1.9 1 1 0 1 1 1 1 Peptidase C26 DUF2435 PF10363.4 KNZ77000.1 - 0.032 14.1 1.7 0.33 10.8 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) dCMP_cyt_deam_1 PF00383.17 KNZ77001.1 - 5.5e-24 83.7 1.3 7.7e-24 83.2 0.9 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region F-box-like PF12937.2 KNZ77002.1 - 6.7e-06 25.7 4.7 6.7e-06 25.7 3.2 2.1 2 0 0 2 2 2 1 F-box-like Statherin PF03875.8 KNZ77002.1 - 0.14 12.0 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Statherin WD40 PF00400.27 KNZ77003.1 - 3.2e-22 77.5 6.7 0.00023 20.9 0.1 7.3 7 1 0 7 7 7 5 WD domain, G-beta repeat Methyltransf_11 PF08241.7 KNZ77004.1 - 2.8e-10 40.5 0.0 4.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ77004.1 - 1.4e-08 34.6 0.0 2.1e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNZ77004.1 - 1e-06 28.0 0.0 1.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KNZ77004.1 - 2.4e-05 24.8 0.0 4.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ77004.1 - 0.00041 20.7 0.0 0.00076 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KNZ77004.1 - 0.0023 17.0 0.0 0.023 13.7 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.1 KNZ77004.1 - 0.0039 16.8 0.0 0.0065 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ77004.1 - 0.0074 16.6 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 KNZ77004.1 - 0.008 14.5 0.0 0.016 13.5 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 KNZ77004.1 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MMR_HSR1 PF01926.18 KNZ77005.1 - 8.8e-11 41.7 0.0 2.5e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KNZ77005.1 - 2.3e-05 23.7 0.0 9e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KNZ77005.1 - 0.0017 18.2 1.6 0.019 14.8 0.5 2.4 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 KNZ77005.1 - 0.018 14.2 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 KNZ77005.1 - 0.033 14.6 0.0 0.079 13.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein PduV-EutP PF10662.4 KNZ77005.1 - 0.1 12.0 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 KNZ77007.1 - 2.3e-12 46.8 0.0 4.8e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KNZ77007.1 - 2.9e-07 30.6 0.0 2.9e-06 27.4 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KNZ77007.1 - 1.2e-06 27.5 0.2 1.7e-05 23.8 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain APS_kinase PF01583.15 KNZ77007.1 - 0.00037 20.1 0.0 0.0016 18.0 0.0 2.0 3 0 0 3 3 3 1 Adenylylsulphate kinase AAA_23 PF13476.1 KNZ77007.1 - 0.0027 18.0 3.0 0.93 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KNZ77007.1 - 0.0028 18.4 0.0 0.029 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain PhoU_div PF01865.11 KNZ77007.1 - 0.0033 16.6 0.1 0.014 14.6 0.1 2.1 1 0 0 1 1 1 1 Protein of unknown function DUF47 AAA_25 PF13481.1 KNZ77007.1 - 0.0051 16.2 0.0 0.037 13.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KNZ77007.1 - 0.008 16.3 1.9 0.042 13.9 0.0 2.9 3 1 0 3 3 2 1 AAA domain AAA_29 PF13555.1 KNZ77007.1 - 0.015 14.7 0.0 0.039 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 KNZ77007.1 - 0.016 15.3 0.0 0.051 13.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 KNZ77007.1 - 0.017 14.8 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 KNZ77007.1 - 0.021 15.0 0.5 0.17 12.0 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KNZ77007.1 - 0.022 13.8 0.0 0.95 8.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.22 KNZ77007.1 - 0.039 14.2 1.4 0.22 11.8 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 KNZ77007.1 - 0.054 13.7 1.0 0.43 10.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KNZ77007.1 - 0.063 13.1 0.2 0.33 10.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KNZ77007.1 - 0.069 12.7 0.0 0.27 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KNZ77007.1 - 0.074 12.5 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein T2SE PF00437.15 KNZ77007.1 - 0.079 11.8 0.0 0.21 10.4 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 KNZ77007.1 - 0.092 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF869 PF05911.6 KNZ77007.1 - 0.3 9.2 6.6 0.061 11.5 2.1 1.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) Phosducin PF02114.11 KNZ77007.1 - 0.47 9.1 4.3 0.093 11.4 0.3 1.7 2 0 0 2 2 2 0 Phosducin CoaE PF01121.15 KNZ77007.1 - 0.87 8.9 4.2 9 5.6 0.0 3.1 3 0 0 3 3 3 0 Dephospho-CoA kinase Baculo_PEP_C PF04513.7 KNZ77007.1 - 1.2 8.9 6.6 8.1 6.2 0.4 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.27 KNZ77008.1 - 5.5e-186 596.7 59.6 6.3e-14 51.2 0.1 15.2 15 0 0 15 15 15 15 WD domain, G-beta repeat PD40 PF07676.7 KNZ77008.1 - 1.8e-31 107.2 24.3 0.056 13.1 0.2 15.3 15 0 0 15 15 15 11 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KNZ77008.1 - 8.1e-27 94.1 0.2 0.00025 20.8 0.0 6.5 1 1 6 7 7 7 7 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KNZ77008.1 - 1.1e-19 70.0 17.4 0.00011 20.6 0.2 7.2 1 1 5 7 7 7 6 Cytochrome D1 heme domain HARP PF07443.8 KNZ77008.1 - 3.9e-11 42.1 0.2 4.4 6.7 0.0 10.4 13 0 0 13 13 13 1 HepA-related protein (HARP) PLD_C PF12357.3 KNZ77008.1 - 2.7e-08 33.2 6.0 2.8 7.5 0.0 9.7 8 5 3 12 12 12 1 Phospholipase D C terminal Proteasome_A_N PF10584.4 KNZ77008.1 - 7e-08 31.6 25.2 6.1 6.2 0.0 13.7 14 0 0 14 14 14 1 Proteasome subunit A N-terminal signature DUF1652 PF07865.6 KNZ77008.1 - 1.2e-07 31.2 0.0 44 3.7 0.0 9.4 10 1 1 11 11 11 0 Protein of unknown function (DUF1652) TolB_N PF04052.8 KNZ77008.1 - 3.7e-06 26.9 0.1 55 3.9 0.0 8.9 11 0 0 11 11 10 0 TolB amino-terminal domain DUF3312 PF11768.3 KNZ77008.1 - 9.4e-06 24.1 0.2 5 5.2 0.0 6.3 4 2 4 9 9 9 1 Protein of unknown function (DUF3312) Mid2 PF04478.7 KNZ77008.1 - 0.0025 17.2 15.8 15 4.9 0.1 8.2 3 1 8 11 11 11 0 Mid2 like cell wall stress sensor IFT20 PF14931.1 KNZ77008.1 - 0.06 13.2 0.0 1.2e+02 2.6 0.0 5.4 7 0 0 7 7 7 0 Intraflagellar transport complex B, subunit 20 Surfac_D-trimer PF09006.6 KNZ77008.1 - 0.099 12.3 4.5 13 5.5 0.0 6.5 9 0 0 9 9 9 0 Lung surfactant protein D coiled-coil trimerisation AcetylCoA_hyd_C PF13336.1 KNZ77008.1 - 0.14 11.8 9.3 16 5.1 0.0 6.4 7 1 1 8 8 8 0 Acetyl-CoA hydrolase/transferase C-terminal domain NACHT PF05729.7 KNZ77009.1 - 6.3e-13 48.7 0.0 1.2e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KNZ77009.1 - 1.3e-07 31.8 0.0 5.4e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KNZ77009.1 - 3.5e-06 26.0 0.4 1.5e-05 24.0 0.0 2.2 2 1 0 2 2 2 1 NB-ARC domain PhoU_div PF01865.11 KNZ77009.1 - 0.00045 19.4 0.3 0.0011 18.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF47 APS_kinase PF01583.15 KNZ77009.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 KNZ77009.1 - 0.0015 18.7 0.0 0.0082 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KNZ77009.1 - 0.0018 17.7 0.0 0.0045 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KNZ77009.1 - 0.002 18.3 0.0 0.046 13.9 0.0 2.9 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KNZ77009.1 - 0.0023 18.7 0.3 0.027 15.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KNZ77009.1 - 0.0089 16.1 0.0 0.045 13.9 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.1 KNZ77009.1 - 0.014 14.9 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 KNZ77009.1 - 0.019 14.6 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 KNZ77009.1 - 0.02 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KNZ77009.1 - 0.021 15.1 0.0 0.24 11.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 KNZ77009.1 - 0.025 14.9 2.4 0.48 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KNZ77009.1 - 0.026 13.5 0.0 0.052 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KNZ77009.1 - 0.048 13.9 0.2 0.21 11.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KNZ77009.1 - 0.055 13.3 0.0 0.24 11.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 KNZ77009.1 - 0.08 11.8 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 KNZ77009.1 - 0.088 12.3 0.0 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Laminin_II PF06009.7 KNZ77009.1 - 0.7 9.6 4.6 7.5 6.3 0.0 3.0 3 0 0 3 3 3 0 Laminin Domain II WD40 PF00400.27 KNZ77010.1 - 1.4e-129 417.9 49.0 1.1e-14 53.6 0.3 10.2 10 0 0 10 10 10 10 WD domain, G-beta repeat PD40 PF07676.7 KNZ77010.1 - 1.5e-23 82.0 18.8 0.26 11.0 0.0 10.4 10 0 0 10 10 10 10 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KNZ77010.1 - 4.5e-17 62.4 0.4 0.0026 17.4 0.0 4.7 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KNZ77010.1 - 2.2e-10 39.4 6.8 0.035 12.3 0.0 4.2 2 1 2 4 4 4 4 Cytochrome D1 heme domain Thioredox_DsbH PF03190.10 KNZ77010.1 - 8.4e-08 32.1 0.0 3.8 7.1 0.0 6.4 3 2 4 7 7 7 2 Protein of unknown function, DUF255 HARP PF07443.8 KNZ77010.1 - 7.9e-07 28.3 0.0 4.9 6.6 0.0 6.4 8 0 0 8 8 8 2 HepA-related protein (HARP) AcetylCoA_hyd_C PF13336.1 KNZ77010.1 - 4.3e-06 26.4 1.8 5.4 6.6 0.0 6.4 3 2 5 8 8 8 1 Acetyl-CoA hydrolase/transferase C-terminal domain Proteasome_A_N PF10584.4 KNZ77010.1 - 1.5e-05 24.2 30.5 2.8 7.3 0.1 12.4 13 0 0 13 13 13 1 Proteasome subunit A N-terminal signature PLD_C PF12357.3 KNZ77010.1 - 0.0006 19.2 3.6 23 4.5 0.0 7.1 6 3 1 8 8 8 0 Phospholipase D C terminal CPSF_A PF03178.10 KNZ77010.1 - 0.0011 18.0 0.4 17 4.3 0.0 5.0 1 1 1 4 4 4 0 CPSF A subunit region Arena_nucleocap PF00843.12 KNZ77010.1 - 0.0083 14.0 3.4 6.3 4.5 0.0 4.7 3 2 3 6 6 6 1 Arenavirus nucleocapsid protein DUF1258 PF06869.7 KNZ77010.1 - 0.037 13.1 1.1 17 4.3 0.0 4.7 1 1 4 7 7 7 0 Protein of unknown function (DUF1258) DUF4221 PF13970.1 KNZ77010.1 - 0.11 11.8 0.1 19 4.4 0.0 4.1 1 1 4 6 6 6 0 Domain of unknown function (DUF4221) zf-LYAR PF08790.6 KNZ77010.1 - 0.12 12.0 0.2 1.2 8.8 0.1 2.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Mid2 PF04478.7 KNZ77010.1 - 0.25 10.7 5.3 36 3.7 0.0 5.3 2 2 4 7 7 7 0 Mid2 like cell wall stress sensor Pkinase PF00069.20 KNZ77012.1 - 2.5e-29 102.2 0.0 5.2e-29 101.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77012.1 - 4.4e-11 42.3 0.0 5.7e-05 22.3 0.0 3.0 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 KNZ77012.1 - 0.025 13.5 0.1 2.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Lactamase_B PF00753.22 KNZ77012.1 - 0.069 12.7 0.1 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Choline_kinase PF01633.15 KNZ77013.1 - 0.0021 17.6 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KNZ77013.1 - 0.0021 17.8 0.0 0.0036 17.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4325 PF14213.1 KNZ77013.1 - 0.14 11.8 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4325) WD40 PF00400.27 KNZ77014.1 - 0.0054 16.5 1.5 3.2 7.7 0.0 2.9 2 1 0 2 2 2 2 WD domain, G-beta repeat NAD_binding_4 PF07993.7 KNZ77016.1 - 6.8e-06 25.1 0.0 7.2e-06 25.1 0.0 1.0 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KNZ77016.1 - 0.00011 21.6 0.0 0.00012 21.5 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family p450 PF00067.17 KNZ77018.1 - 8.8e-67 225.6 2.6 2e-66 224.4 1.8 1.6 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KNZ77019.1 - 6.5e-64 216.1 0.4 5.1e-63 213.2 0.3 2.1 1 1 0 1 1 1 1 Cytochrome P450 CrtC PF07143.6 KNZ77020.1 - 0.016 14.4 0.0 0.016 14.4 0.0 1.7 2 0 0 2 2 2 0 Hydroxyneurosporene synthase (CrtC) Calcipressin PF04847.7 KNZ77023.1 - 1.8e-34 118.9 0.0 2.4e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Calcipressin RRM_1 PF00076.17 KNZ77023.1 - 0.032 13.8 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1014 PF06244.7 KNZ77024.1 - 6.7e-26 90.8 15.7 6.7e-26 90.8 10.9 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) Totivirus_coat PF05518.6 KNZ77024.1 - 0.86 7.3 5.5 1 7.0 3.8 1.1 1 0 0 1 1 1 0 Totivirus coat protein Allexi_40kDa PF05549.6 KNZ77024.1 - 1.8 7.7 4.1 3.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Glyoxalase_3 PF13468.1 KNZ77025.1 - 1.5e-28 99.8 0.0 2.2e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Peptidase_S10 PF00450.17 KNZ77026.1 - 3e-113 379.1 0.0 4.2e-113 378.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KNZ77026.1 - 0.00091 19.1 0.0 0.0056 16.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family PP2C PF00481.16 KNZ77029.1 - 3e-23 82.5 0.0 8.3e-23 81.0 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KNZ77029.1 - 2.9e-06 26.8 0.0 6.9e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C DUF21 PF01595.15 KNZ77030.1 - 2.2e-25 89.0 0.6 3.6e-25 88.3 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KNZ77030.1 - 0.00054 19.6 0.0 0.49 10.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain VSP PF03302.8 KNZ77030.1 - 0.0082 14.8 148.8 0.012 14.2 21.7 6.3 1 1 5 6 6 6 5 Giardia variant-specific surface protein hEGF PF12661.2 KNZ77030.1 - 0.012 15.6 4.8 0.012 15.6 3.3 7.0 7 0 0 7 7 7 0 Human growth factor-like EGF DUF4381 PF14316.1 KNZ77030.1 - 0.044 13.8 1.5 0.13 12.3 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4131 PF13567.1 KNZ77030.1 - 7 6.0 5.8 3.2 7.1 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pkinase PF00069.20 KNZ77031.1 - 2.9e-38 131.5 0.0 5.6e-38 130.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77031.1 - 1.8e-15 56.7 0.0 2.4e-15 56.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase tRNA_U5-meth_tr PF05958.6 KNZ77032.1 - 1.9e-16 59.6 0.0 2.1e-15 56.2 0.0 2.3 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 KNZ77032.1 - 2.1e-07 30.6 0.0 5.8e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KNZ77032.1 - 2.3e-07 30.5 0.0 4.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 KNZ77032.1 - 1.2e-05 25.8 0.0 2.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KNZ77032.1 - 2.2e-05 23.9 0.0 4.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 KNZ77032.1 - 2.2e-05 24.4 0.0 4.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KNZ77032.1 - 4.4e-05 23.1 0.4 0.00041 20.0 0.0 2.4 2 1 0 3 3 3 1 Met-10+ like-protein Methyltransf_11 PF08241.7 KNZ77032.1 - 0.0007 20.0 0.0 0.0021 18.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KNZ77032.1 - 0.00098 18.3 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KNZ77032.1 - 0.0014 17.9 0.0 0.0031 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 KNZ77032.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TPMT PF05724.6 KNZ77032.1 - 0.017 14.5 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TRM PF02005.11 KNZ77032.1 - 0.027 13.3 0.0 0.045 12.6 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase TRAM PF01938.15 KNZ77032.1 - 0.037 13.8 0.0 0.094 12.5 0.0 1.7 1 0 0 1 1 1 0 TRAM domain Methyltransf_12 PF08242.7 KNZ77032.1 - 0.13 12.7 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cerato-platanin PF07249.7 KNZ77033.1 - 7.3e-40 135.6 0.4 8.5e-40 135.4 0.3 1.0 1 0 0 1 1 1 1 Cerato-platanin Glyco_hydro_45 PF02015.11 KNZ77033.1 - 0.0064 16.5 0.2 0.0075 16.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Barwin PF00967.12 KNZ77033.1 - 0.0065 16.1 0.1 0.0085 15.7 0.1 1.4 1 1 0 1 1 1 1 Barwin family Pec_lyase_C PF00544.14 KNZ77035.1 - 0.21 11.0 3.9 0.29 10.5 2.2 1.6 1 1 0 1 1 1 0 Pectate lyase Helitron_like_N PF14214.1 KNZ77036.1 - 7.4e-61 205.0 0.3 9.3e-61 204.7 0.2 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 KNZ77036.1 - 0.044 12.4 0.2 0.054 12.1 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Abhydrolase_5 PF12695.2 KNZ77037.1 - 3.3e-21 75.5 0.0 4.7e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ77037.1 - 3.5e-14 53.2 1.3 9.7e-12 45.2 0.9 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ77037.1 - 4.6e-07 29.6 0.1 2.5e-06 27.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KNZ77037.1 - 6.1e-06 25.6 0.0 0.0001 21.6 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 KNZ77037.1 - 0.00014 21.6 0.1 0.0015 18.2 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 KNZ77037.1 - 0.00032 20.2 0.0 0.75 9.1 0.0 2.9 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KNZ77037.1 - 0.0012 18.0 0.0 0.035 13.3 0.0 2.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.20 KNZ77037.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF1057 PF06342.7 KNZ77037.1 - 0.0072 15.1 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.8 KNZ77037.1 - 0.01 15.4 0.1 0.019 14.5 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 KNZ77037.1 - 0.022 13.2 0.2 0.041 12.3 0.1 1.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 KNZ77037.1 - 0.049 13.4 0.1 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase DUF829 PF05705.9 KNZ77037.1 - 0.06 13.0 0.0 0.46 10.1 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) PGAP1 PF07819.8 KNZ77037.1 - 0.087 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF1100 PF06500.6 KNZ77037.1 - 0.14 10.7 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Cu-oxidase_3 PF07732.10 KNZ77039.1 - 8.2e-42 141.6 1.5 4.8e-39 132.7 0.1 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KNZ77039.1 - 4.9e-41 140.2 0.1 1.8e-39 135.1 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KNZ77039.1 - 1.4e-34 118.5 7.6 4.1e-31 107.3 0.1 3.9 3 1 0 3 3 3 3 Multicopper oxidase RVP_2 PF08284.6 KNZ77041.1 - 0.0044 16.9 0.0 0.0059 16.5 0.0 1.3 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KNZ77041.1 - 0.047 14.1 0.0 0.069 13.6 0.0 1.4 1 1 0 1 1 1 0 Aspartyl protease ABC_membrane PF00664.18 KNZ77042.1 - 6.3e-48 163.5 17.5 1.3e-29 103.5 4.4 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 KNZ77042.1 - 4.6e-41 140.3 0.0 6e-26 91.3 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KNZ77042.1 - 6.2e-10 39.5 1.1 0.022 14.7 0.2 4.2 2 2 0 4 4 4 3 AAA domain AAA_25 PF13481.1 KNZ77042.1 - 1.1e-09 37.9 2.0 0.0022 17.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 KNZ77042.1 - 1.4e-09 37.4 0.7 0.16 11.1 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KNZ77042.1 - 5.2e-09 36.7 0.6 4.9e-05 23.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KNZ77042.1 - 9.1e-07 28.3 0.1 0.047 13.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KNZ77042.1 - 1.9e-05 23.7 0.0 0.028 13.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KNZ77042.1 - 6.6e-05 22.8 0.1 0.061 13.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KNZ77042.1 - 8.8e-05 22.9 0.1 0.69 10.4 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 KNZ77042.1 - 0.00012 21.6 0.3 0.23 10.8 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 KNZ77042.1 - 0.0002 21.3 0.8 0.33 10.9 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KNZ77042.1 - 0.00021 22.1 0.1 1.8 9.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KNZ77042.1 - 0.00033 20.7 1.6 0.55 10.3 0.0 3.3 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 KNZ77042.1 - 0.00041 20.0 0.2 0.58 9.8 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KNZ77042.1 - 0.00042 20.1 0.5 0.061 13.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 KNZ77042.1 - 0.00078 18.9 0.6 2 7.7 0.2 3.0 3 0 0 3 3 3 2 AAA-like domain Adeno_IVa2 PF02456.10 KNZ77042.1 - 0.00093 17.9 0.0 0.029 13.0 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein Dynamin_N PF00350.18 KNZ77042.1 - 0.0027 17.5 3.7 0.63 9.8 0.0 3.1 3 0 0 3 3 3 2 Dynamin family DUF258 PF03193.11 KNZ77042.1 - 0.011 14.9 0.1 2.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KNZ77042.1 - 0.014 15.1 0.1 1 8.9 0.0 2.8 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 KNZ77042.1 - 0.019 14.6 2.5 4 7.0 0.1 3.2 3 0 0 3 3 3 0 NACHT domain AAA_5 PF07728.9 KNZ77042.1 - 0.021 14.5 1.0 7.2 6.3 0.0 3.6 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) cobW PF02492.14 KNZ77042.1 - 0.044 13.2 1.0 3 7.2 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 KNZ77042.1 - 0.044 13.9 1.0 2 8.6 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KNZ77042.1 - 0.047 13.4 0.1 1.8 8.3 0.0 3.3 4 0 0 4 4 2 0 Part of AAA domain IstB_IS21 PF01695.12 KNZ77042.1 - 0.059 12.7 0.2 7.5 5.9 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_18 PF13238.1 KNZ77042.1 - 0.065 13.5 2.6 4.6 7.5 0.0 3.4 4 0 0 4 4 2 0 AAA domain AAA_33 PF13671.1 KNZ77042.1 - 0.068 13.0 0.4 3.6 7.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KNZ77042.1 - 0.089 11.8 0.1 4.5 6.3 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin DEAD PF00270.24 KNZ77042.1 - 0.11 11.9 0.1 17 4.8 0.0 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase Pox_A32 PF04665.7 KNZ77042.1 - 0.17 11.1 0.5 4.8 6.3 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ResIII PF04851.10 KNZ77042.1 - 0.22 11.3 0.0 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_15 PF13175.1 KNZ77042.1 - 0.23 10.4 0.0 1.4 7.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF3093 PF11292.3 KNZ77042.1 - 0.36 10.6 6.5 0.034 13.9 0.4 2.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3093) PduV-EutP PF10662.4 KNZ77042.1 - 2.1 7.8 4.7 6 6.3 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ebola_NP PF05505.7 KNZ77043.1 - 0.56 8.2 2.3 0.7 7.8 1.6 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DDA1 PF10172.4 KNZ77046.1 - 0.25 11.1 0.0 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase DUF892 PF05974.7 KNZ77047.1 - 0.03 14.1 1.5 0.064 13.0 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF892) LRR_5 PF13306.1 KNZ77047.1 - 0.052 13.2 0.1 0.087 12.5 0.1 1.3 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) Alpha_adaptinC2 PF02883.15 KNZ77047.1 - 0.12 12.7 0.9 0.28 11.4 0.6 1.6 1 0 0 1 1 1 0 Adaptin C-terminal domain Pex24p PF06398.6 KNZ77048.1 - 7.9 5.1 10.2 0.28 9.9 0.1 2.1 1 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Ist1 PF03398.9 KNZ77049.1 - 1.2e-27 96.3 0.0 1.7e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.13 KNZ77049.1 - 2.2e-09 37.1 0.1 3e-07 30.1 0.0 2.6 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PIG-H PF10181.4 KNZ77050.1 - 5.7e-11 41.9 0.0 9.5e-11 41.1 0.0 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component TRI5 PF06330.6 KNZ77053.1 - 3.5e-13 48.9 1.6 4.7e-13 48.5 1.0 1.2 1 1 0 1 1 1 1 Trichodiene synthase (TRI5) p450 PF00067.17 KNZ77054.1 - 2.4e-53 181.2 0.0 2.2e-39 135.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 RVP_2 PF08284.6 KNZ77056.1 - 0.00081 19.3 0.3 0.0013 18.7 0.2 1.4 1 1 0 1 1 1 1 Retroviral aspartyl protease Tim17 PF02466.14 KNZ77057.1 - 0.22 11.5 0.2 0.22 11.5 0.1 3.5 4 1 1 5 5 5 0 Tim17/Tim22/Tim23/Pmp24 family AMP-binding PF00501.23 KNZ77059.1 - 6.5e-85 285.0 0.0 1.1e-84 284.2 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KNZ77059.1 - 5.9e-11 43.1 2.6 1.4e-10 41.9 1.8 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 KNZ77060.1 - 2e-25 87.7 28.4 1.9e-10 40.1 0.9 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF3312 PF11768.3 KNZ77060.1 - 0.088 11.0 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF35 PF01796.12 KNZ77060.1 - 0.14 12.3 0.7 23 5.2 0.0 3.2 3 0 0 3 3 3 0 DUF35 OB-fold domain PD40 PF07676.7 KNZ77060.1 - 0.2 11.3 10.1 0.25 11.0 0.0 4.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Ribosomal_L7Ae PF01248.21 KNZ77061.1 - 6.5e-26 89.6 2.9 7.4e-26 89.4 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2042 PF09743.4 KNZ77061.1 - 0.1 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2042) TPR_10 PF13374.1 KNZ77062.1 - 2e-106 345.3 33.9 5.7e-09 35.6 0.0 16.4 16 0 0 16 16 16 15 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ77062.1 - 6.7e-78 256.6 47.0 1.5e-13 50.5 0.1 10.4 5 2 4 12 12 12 10 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ77062.1 - 2.2e-15 56.8 28.7 0.017 15.7 0.9 10.3 4 2 3 10 10 10 6 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ77062.1 - 4.4e-15 54.5 16.3 2.1 8.7 0.0 13.5 15 0 0 15 15 14 3 Tetratricopeptide repeat NB-ARC PF00931.17 KNZ77062.1 - 4.6e-15 55.2 0.3 1.2e-14 53.8 0.2 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_4 PF07721.9 KNZ77062.1 - 6.2e-07 29.2 25.7 2.2 8.9 0.7 11.5 13 0 0 13 13 11 1 Tetratricopeptide repeat Patatin PF01734.17 KNZ77062.1 - 9.9e-07 28.8 0.1 9.2e-06 25.7 0.1 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase DUF4404 PF14357.1 KNZ77062.1 - 0.00014 22.1 24.4 3.1 8.2 0.1 9.1 5 2 4 9 9 9 1 Domain of unknown function (DUF4404) AAA_22 PF13401.1 KNZ77062.1 - 0.00029 20.9 0.0 0.00029 20.9 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 KNZ77062.1 - 0.00072 19.5 0.0 0.00072 19.5 0.0 3.6 4 1 0 4 4 4 1 AAA ATPase domain Arch_ATPase PF01637.13 KNZ77062.1 - 0.00092 18.9 1.4 0.043 13.5 0.0 3.3 3 1 0 3 3 3 1 Archaeal ATPase TPR_2 PF07719.12 KNZ77062.1 - 0.0015 18.3 27.7 2.7 8.1 0.1 11.0 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ77062.1 - 0.0042 16.6 25.6 4.8 6.9 0.1 10.9 14 0 0 14 14 14 2 Tetratricopeptide repeat Latarcin PF10279.4 KNZ77062.1 - 0.092 12.9 4.3 6.8 6.9 0.1 4.6 3 1 0 3 3 3 0 Latarcin precursor TPR_19 PF14559.1 KNZ77062.1 - 0.28 11.5 44.3 0.086 13.1 0.9 9.3 5 3 6 12 12 12 0 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ77062.1 - 4.5 7.3 45.9 2.6 8.0 0.1 13.0 15 0 0 15 15 14 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 KNZ77063.1 - 1.8e-51 174.6 0.0 2e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1399 PF07173.7 KNZ77065.1 - 3.9e-20 72.5 0.1 1.4e-18 67.5 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF1399) Chitin_synth_2 PF03142.10 KNZ77066.1 - 4.7e-233 774.3 0.1 6.2e-233 773.9 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KNZ77066.1 - 1.4e-108 363.7 0.0 2.3e-108 363.0 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.1 KNZ77066.1 - 2.9e-20 73.0 0.0 7.6e-16 58.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KNZ77066.1 - 2.3e-17 62.5 1.0 1.6e-13 50.2 0.0 2.9 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 KNZ77066.1 - 1.1e-16 61.0 5.9 1.1e-16 61.0 4.1 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 KNZ77066.1 - 5.6e-13 48.4 0.8 2e-12 46.7 0.2 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.21 KNZ77066.1 - 5.2e-08 32.7 0.0 7.3e-05 22.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KNZ77066.1 - 3.6e-06 26.3 0.0 0.00028 20.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF3253 PF11625.3 KNZ77066.1 - 0.017 14.9 0.0 0.08 12.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) 3Beta_HSD PF01073.14 KNZ77070.1 - 5.7e-31 107.2 0.0 1.6e-30 105.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KNZ77070.1 - 2.1e-13 49.8 0.0 5.5e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.16 KNZ77070.1 - 2.9e-12 46.5 0.0 5e-12 45.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KNZ77070.1 - 0.00014 20.9 0.0 0.0013 17.7 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KNZ77070.1 - 0.00028 20.9 0.0 0.0021 18.1 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KNZ77070.1 - 0.028 14.3 0.0 0.06 13.2 0.0 1.5 1 1 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 KNZ77070.1 - 0.031 13.9 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 KNZ77070.1 - 0.11 11.3 0.0 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain PIF1 PF05970.9 KNZ77072.1 - 8.7e-80 268.3 0.0 9.9e-80 268.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ77072.1 - 0.0038 16.8 0.0 0.0064 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KNZ77072.1 - 0.032 14.0 0.0 0.077 12.8 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KNZ77072.1 - 0.047 13.1 0.1 0.097 12.1 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.6 KNZ77072.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Torsin PhoH PF02562.11 KNZ77072.1 - 0.14 11.3 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Herpes_Helicase PF02689.9 KNZ77073.1 - 0.00021 19.1 0.0 0.00022 19.1 0.0 1.0 1 0 0 1 1 1 1 Helicase CTP_synth_N PF06418.9 KNZ77074.1 - 1.3e-116 388.5 0.3 1.8e-116 388.0 0.2 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KNZ77074.1 - 1.4e-51 174.6 0.0 2.2e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KNZ77074.1 - 0.00019 20.9 0.0 0.00047 19.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KNZ77074.1 - 0.0023 17.3 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DEAD PF00270.24 KNZ77075.1 - 5.4e-34 117.1 0.0 7.9e-33 113.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ77075.1 - 6.1e-16 58.0 1.1 1.1e-15 57.2 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KNZ77075.1 - 0.002 16.9 0.0 0.0042 15.9 0.0 1.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 KNZ77075.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit IF4E PF01652.13 KNZ77076.1 - 1e-49 168.2 0.0 1.5e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E zf-CCHC_2 PF13696.1 KNZ77078.1 - 0.68 9.4 3.9 61 3.2 2.7 2.3 1 1 0 1 1 1 0 Zinc knuckle NAD_binding_4 PF07993.7 KNZ77080.1 - 3.1e-34 118.0 0.0 4.7e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KNZ77080.1 - 3.7e-23 81.6 0.0 6.1e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KNZ77080.1 - 2.5e-05 23.8 0.0 5.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ77080.1 - 0.0037 17.3 0.0 0.14 12.1 0.0 2.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KNZ77080.1 - 0.0084 16.0 0.0 0.034 14.0 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.20 KNZ77080.1 - 0.012 15.8 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site KR PF08659.5 KNZ77080.1 - 0.018 14.7 0.0 0.048 13.3 0.0 1.7 1 1 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 KNZ77080.1 - 0.02 13.5 0.0 0.037 12.7 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDA1_CD39 PF01150.12 KNZ77083.1 - 1.3e-07 30.5 0.0 1.4e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DcpS_C PF11969.3 KNZ77084.1 - 4.2e-12 46.3 0.0 8.3e-12 45.3 0.0 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KNZ77084.1 - 7.5e-10 39.1 0.4 3.7e-08 33.7 0.0 2.3 1 1 1 2 2 2 2 Scavenger mRNA decapping enzyme (DcpS) N-terminal DEDD_Tnp_IS110 PF01548.12 KNZ77084.1 - 0.069 12.8 0.1 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Transposase RVP_2 PF08284.6 KNZ77085.1 - 0.015 15.2 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease FAD_binding_4 PF01565.18 KNZ77086.1 - 1.2e-15 57.1 0.4 5.2e-15 55.1 0.3 2.1 1 1 0 1 1 1 1 FAD binding domain Sugar_tr PF00083.19 KNZ77088.1 - 6.4e-86 288.7 20.5 9.9e-86 288.0 14.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ77088.1 - 2.5e-25 88.9 27.4 2.7e-23 82.2 8.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KNZ77088.1 - 0.015 15.0 7.6 0.041 13.6 0.1 3.6 4 0 0 4 4 4 0 MFS_1 like family TPR_8 PF13181.1 KNZ77092.1 - 0.0021 17.6 7.9 0.087 12.6 0.1 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ77092.1 - 0.0066 16.3 6.9 0.026 14.4 0.9 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ77092.1 - 0.1 12.5 12.7 1.6 8.7 0.1 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat Exo_endo_phos_2 PF14529.1 KNZ77093.1 - 0.00099 18.7 0.2 0.0015 18.1 0.2 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KNZ77093.1 - 0.0094 15.9 0.1 0.01 15.8 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CSTF_C PF14304.1 KNZ77094.1 - 0.079 12.2 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal RNase_H PF00075.19 KNZ77095.1 - 0.057 13.7 0.1 0.088 13.1 0.0 1.4 1 1 0 1 1 1 0 RNase H zf-RVT PF13966.1 KNZ77096.1 - 1.1e-05 25.5 1.1 2.1e-05 24.7 0.9 1.4 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DUF360 PF04020.8 KNZ77099.1 - 0.49 10.7 9.8 0.83 10.0 6.8 1.4 1 1 0 1 1 1 0 Membrane protein of unknown function ATP_transf PF09830.4 KNZ77100.1 - 3.4e-18 65.2 0.1 9.6e-18 63.7 0.0 1.8 2 0 0 2 2 2 1 ATP adenylyltransferase HIT PF01230.18 KNZ77100.1 - 0.021 15.3 0.1 0.39 11.2 0.0 2.4 2 0 0 2 2 2 0 HIT domain MAS20 PF02064.10 KNZ77101.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor DUF1049 PF06305.6 KNZ77101.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) GTF2I PF02946.9 KNZ77101.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 GTF2I-like repeat ILVD_EDD PF00920.16 KNZ77102.1 - 1.1e-132 443.1 0.0 1.3e-132 442.8 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family TPR_1 PF00515.23 KNZ77103.1 - 4.9e-19 67.0 0.0 1.5e-06 27.5 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ77103.1 - 1e-15 56.3 0.1 3.2e-05 23.5 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ77103.1 - 1e-15 57.1 0.2 9.3e-11 41.2 0.5 2.8 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 KNZ77103.1 - 2.3e-13 49.8 2.6 6.5e-06 26.0 0.4 3.9 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ77103.1 - 3.9e-11 43.3 0.5 1.6e-06 28.5 0.0 3.9 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ77103.1 - 8.3e-09 34.6 0.0 0.045 13.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ77103.1 - 1.8e-08 34.2 0.3 0.038 14.6 0.0 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ77103.1 - 2.7e-07 29.8 0.0 0.072 12.9 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ77103.1 - 1.2e-06 28.1 0.3 0.31 11.3 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ77103.1 - 1.9e-06 27.6 1.8 0.055 13.4 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ77103.1 - 1.2e-05 25.5 0.7 0.029 14.7 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ77103.1 - 7.7e-05 22.8 0.2 1.5 9.4 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 KNZ77103.1 - 0.0071 15.4 0.3 0.39 9.7 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ77103.1 - 0.0096 15.7 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KNZ77103.1 - 0.01 15.9 0.3 0.094 12.8 0.2 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.9 KNZ77103.1 - 0.023 13.8 0.0 0.066 12.3 0.0 1.7 1 0 0 1 1 1 0 Coatomer epsilon subunit COQ9 PF08511.6 KNZ77103.1 - 0.052 13.0 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 COQ9 AAA_11 PF13086.1 KNZ77104.1 - 3.1e-32 112.0 0.7 7.3e-32 110.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KNZ77104.1 - 5.6e-32 110.7 0.0 1.1e-31 109.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KNZ77104.1 - 1.5e-07 31.2 0.3 1e-05 25.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KNZ77104.1 - 1.9e-07 30.7 0.2 4.6e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 KNZ77104.1 - 0.0038 16.3 0.2 0.015 14.3 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA_5 PF07728.9 KNZ77104.1 - 0.093 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.16 KNZ77104.1 - 0.11 11.8 0.7 0.49 9.6 0.4 2.3 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain PAC2 PF09754.4 KNZ77105.1 - 5e-24 85.3 0.0 8e-24 84.7 0.0 1.5 1 1 0 1 1 1 1 PAC2 family NUC173 PF08161.7 KNZ77106.1 - 1.3e-37 129.0 0.0 4.4e-35 120.8 0.0 3.0 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.17 KNZ77106.1 - 0.00082 19.2 0.5 6.3 7.1 0.0 4.4 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 KNZ77106.1 - 0.00085 19.5 0.2 11 6.4 0.0 4.7 6 1 0 6 6 6 2 HEAT repeats Cnd1 PF12717.2 KNZ77106.1 - 0.12 12.1 0.0 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 KNZ77106.1 - 0.15 10.7 6.5 0.11 11.2 0.2 2.8 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal Phlebovirus_G1 PF07243.6 KNZ77106.1 - 0.3 9.1 0.1 0.45 8.5 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 ABC_tran PF00005.22 KNZ77107.1 - 5.3e-43 146.6 0.0 5.9e-24 84.9 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KNZ77107.1 - 3.8e-14 53.3 0.3 0.0082 16.1 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 KNZ77107.1 - 2.8e-13 49.6 0.0 2.6e-05 23.5 0.0 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 KNZ77107.1 - 1e-07 31.4 0.1 2e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_17 PF13207.1 KNZ77107.1 - 1.2e-06 29.2 0.3 0.093 13.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KNZ77107.1 - 1.7e-06 27.4 1.5 0.062 12.8 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KNZ77107.1 - 4e-06 26.7 0.0 0.046 13.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KNZ77107.1 - 4.5e-06 27.1 0.0 0.054 13.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 KNZ77107.1 - 1.7e-05 25.2 0.2 0.021 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KNZ77107.1 - 2.8e-05 24.0 0.1 0.18 11.5 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function DUF87 AAA_22 PF13401.1 KNZ77107.1 - 3.6e-05 23.9 0.2 0.17 12.0 0.1 3.7 3 1 0 3 3 3 1 AAA domain HEAT PF02985.17 KNZ77107.1 - 7.6e-05 22.4 6.7 2.8 8.2 0.1 6.3 6 0 0 6 6 6 1 HEAT repeat AAA_10 PF12846.2 KNZ77107.1 - 8.1e-05 22.2 0.9 0.38 10.1 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain MobB PF03205.9 KNZ77107.1 - 0.00012 21.8 0.1 0.2 11.3 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KNZ77107.1 - 0.00014 21.1 0.2 0.079 12.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KNZ77107.1 - 0.00019 21.4 2.4 1.4 8.8 0.1 4.1 4 1 0 4 4 3 1 AAA ATPase domain NACHT PF05729.7 KNZ77107.1 - 0.00037 20.1 0.4 0.21 11.2 0.0 3.1 3 0 0 3 3 3 1 NACHT domain ArgK PF03308.11 KNZ77107.1 - 0.00041 19.2 0.5 0.23 10.2 0.1 2.3 2 0 0 2 2 2 2 ArgK protein AAA_28 PF13521.1 KNZ77107.1 - 0.00049 20.0 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KNZ77107.1 - 0.00063 19.6 0.2 0.53 10.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 KNZ77107.1 - 0.0011 18.4 0.9 8.4 5.7 0.0 4.0 3 1 0 4 4 4 0 AAA domain AAA_18 PF13238.1 KNZ77107.1 - 0.0012 19.2 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KNZ77107.1 - 0.0014 18.5 0.6 6.9 6.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 KNZ77107.1 - 0.0023 17.7 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 KNZ77107.1 - 0.0038 16.9 0.8 6.4 6.4 0.0 3.4 4 0 0 4 4 3 0 Archaeal ATPase Dynamin_N PF00350.18 KNZ77107.1 - 0.0069 16.2 0.0 0.16 11.7 0.0 2.7 3 0 0 3 3 3 1 Dynamin family AAA_15 PF13175.1 KNZ77107.1 - 0.0072 15.4 0.0 11 4.9 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain HEAT_EZ PF13513.1 KNZ77107.1 - 0.0079 16.6 9.2 1.2 9.7 0.5 4.6 2 2 3 5 5 4 1 HEAT-like repeat Adaptin_N PF01602.15 KNZ77107.1 - 0.0096 14.2 0.6 0.18 10.0 0.3 2.1 2 0 0 2 2 2 1 Adaptin N terminal region FtsK_SpoIIIE PF01580.13 KNZ77107.1 - 0.01 15.3 0.2 1 8.7 0.0 3.4 3 1 0 3 3 3 0 FtsK/SpoIIIE family AAA_13 PF13166.1 KNZ77107.1 - 0.01 14.3 0.0 1.1 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KNZ77107.1 - 0.012 15.8 0.2 5.1 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 KNZ77107.1 - 0.014 14.9 0.7 8.9 5.8 0.0 3.2 4 0 0 4 4 3 0 AAA domain cobW PF02492.14 KNZ77107.1 - 0.017 14.6 1.4 10 5.4 0.0 3.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 KNZ77107.1 - 0.025 14.1 0.3 5 6.5 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 KNZ77107.1 - 0.044 13.2 0.1 5.3 6.5 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 KNZ77107.1 - 0.062 12.5 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF3584 PF12128.3 KNZ77107.1 - 0.086 10.1 2.0 3.2 4.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) NTPase_1 PF03266.10 KNZ77107.1 - 0.089 12.4 1.0 15 5.2 0.2 3.3 3 0 0 3 3 3 0 NTPase Zeta_toxin PF06414.7 KNZ77107.1 - 0.091 11.8 0.4 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.17 KNZ77107.1 - 0.14 10.9 0.7 9.9 4.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 KNZ77107.1 - 0.17 12.1 0.1 3.4 7.8 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) MutS_V PF00488.16 KNZ77107.1 - 0.2 11.0 1.2 14 4.9 0.0 2.7 3 0 0 3 3 2 0 MutS domain V G-alpha PF00503.15 KNZ77107.1 - 0.21 10.2 0.2 0.51 8.9 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.1 KNZ77107.1 - 0.72 9.3 1.9 27 4.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain Homeobox PF00046.24 KNZ77108.1 - 3.2e-15 55.4 5.0 6.4e-15 54.5 3.5 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KNZ77108.1 - 0.0022 17.6 0.1 0.0047 16.6 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain zf-H2C2_2 PF13465.1 KNZ77109.1 - 4e-06 26.8 2.7 0.0006 19.9 0.1 2.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KNZ77109.1 - 1.8e-05 24.7 0.4 1.8e-05 24.7 0.3 2.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ77109.1 - 0.0032 17.6 1.1 0.0063 16.7 0.2 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger BolA PF01722.13 KNZ77110.1 - 5.7e-17 61.4 0.6 9.8e-17 60.6 0.4 1.4 1 1 0 1 1 1 1 BolA-like protein PIF1 PF05970.9 KNZ77114.1 - 2.4e-24 85.9 0.0 3.1e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Phage_GPA PF05840.8 KNZ77115.1 - 0.0013 17.5 0.0 0.0018 17.0 0.0 1.1 1 0 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) DNA_ligase_A_M PF01068.16 KNZ77116.1 - 1.6e-41 141.9 0.0 4.5e-41 140.4 0.0 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KNZ77116.1 - 4.1e-35 121.1 0.0 9.4e-35 120.0 0.0 1.6 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KNZ77116.1 - 2.4e-11 43.8 0.0 1.2e-07 32.0 0.0 3.0 1 1 1 2 2 2 2 ATP dependent DNA ligase C terminal region PhoD PF09423.5 KNZ77118.1 - 1.2e-119 399.8 0.0 2.6e-119 398.7 0.0 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase Metallophos PF00149.23 KNZ77118.1 - 0.0025 17.2 0.1 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PIF1 PF05970.9 KNZ77119.1 - 6.1e-17 61.6 0.2 6.4e-17 61.5 0.2 1.0 1 0 0 1 1 1 1 PIF1-like helicase Viral_helicase1 PF01443.13 KNZ77119.1 - 0.011 15.2 0.1 0.011 15.2 0.1 1.0 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.6 KNZ77119.1 - 0.025 14.4 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 Torsin AAA_30 PF13604.1 KNZ77119.1 - 0.039 13.5 0.0 0.039 13.5 0.0 1.0 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KNZ77119.1 - 0.052 12.7 0.0 0.052 12.7 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 KNZ77119.1 - 0.054 12.9 0.2 0.056 12.8 0.1 1.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KNZ77119.1 - 0.1 12.7 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.10 KNZ77119.1 - 0.16 11.8 0.0 0.16 11.7 0.0 1.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PIF1 PF05970.9 KNZ77120.1 - 2.7e-09 36.4 0.0 3.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Nucleoporin_C PF03177.9 KNZ77121.1 - 0.044 12.3 0.2 0.07 11.6 0.0 1.4 2 0 0 2 2 2 0 Non-repetitive/WGA-negative nucleoporin C-terminal ATP_bind_2 PF03668.10 KNZ77122.1 - 2.1e-05 23.7 0.0 3.8e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 P-loop ATPase protein family Zn_clus PF00172.13 KNZ77123.1 - 6.5e-08 32.3 11.3 6.5e-08 32.3 7.9 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SSP160 PF06933.6 KNZ77123.1 - 0.066 11.1 0.0 0.097 10.6 0.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FAD_binding_4 PF01565.18 KNZ77124.1 - 1.1e-29 102.7 2.4 2.5e-29 101.5 1.6 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KNZ77124.1 - 2.2e-16 59.4 0.3 4.1e-16 58.6 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KNZ77124.1 - 0.0049 16.0 0.1 0.009 15.1 0.1 1.3 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.18 KNZ77125.1 - 3.9e-26 91.1 1.6 7.2e-26 90.3 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KNZ77125.1 - 1e-11 44.5 1.6 2.5e-11 43.2 0.8 1.9 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 KNZ77125.1 - 0.11 11.6 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Beta-lactamase PF00144.19 KNZ77126.1 - 1e-09 37.8 0.1 8.9e-09 34.8 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase FA_desaturase PF00487.19 KNZ77129.1 - 2.8e-25 89.2 25.2 4.9e-25 88.4 17.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KNZ77129.1 - 0.00054 19.9 0.1 0.00093 19.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.19 KNZ77130.1 - 7.8e-25 87.7 30.7 1.1e-24 87.2 21.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KNZ77130.1 - 8.6e-06 25.8 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Ribosomal_L33 PF00471.15 KNZ77131.1 - 0.0044 17.2 0.6 27 5.0 0.0 3.3 3 0 0 3 3 3 3 Ribosomal protein L33 PIF1 PF05970.9 KNZ77134.1 - 2.8e-07 29.8 0.0 3.8e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ77134.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain zf-CCHC PF00098.18 KNZ77137.1 - 0.14 12.1 0.8 0.23 11.4 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle SpoVR PF04293.8 KNZ77140.1 - 0.11 10.8 2.3 0.19 10.0 1.6 1.3 1 0 0 1 1 1 0 SpoVR like protein ECH PF00378.15 KNZ77143.1 - 1.4e-44 152.0 0.0 1.6e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Sec10 PF07393.6 KNZ77144.1 - 1.1e-221 737.8 0.0 1.4e-221 737.4 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Peptidase_S46 PF10459.4 KNZ77144.1 - 0.0018 16.8 0.1 0.003 16.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase S46 RIX1 PF08167.7 KNZ77145.1 - 1.3e-24 86.7 2.9 1.3e-24 86.7 2.0 2.7 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis BTAD PF03704.12 KNZ77146.1 - 0.011 15.9 0.2 0.019 15.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial transcriptional activator domain TPR_9 PF13371.1 KNZ77146.1 - 0.09 12.6 0.2 0.23 11.3 0.1 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat RNA_pol_I_TF PF04090.7 KNZ77146.1 - 0.096 11.9 0.2 0.25 10.5 0.1 1.6 1 1 1 2 2 2 0 RNA polymerase I specific initiation factor RNA_pol_Rpb1_5 PF04998.12 KNZ77148.1 - 1e-87 293.9 0.0 2.6e-87 292.5 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KNZ77148.1 - 2.2e-53 180.5 0.0 4e-53 179.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KNZ77148.1 - 1.1e-36 125.9 0.0 3.4e-36 124.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KNZ77148.1 - 3.1e-29 102.3 8.7 2e-22 79.9 0.0 4.6 4 1 0 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 KNZ77148.1 - 9.6e-21 73.5 0.0 3.1e-20 71.9 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Hid1 PF12722.2 KNZ77148.1 - 7 4.1 3.6 13 3.3 2.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleoporin_FG PF13634.1 KNZ77149.1 - 0.38 11.0 4.8 11 6.3 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin FG repeat region E_Pc_C PF06752.7 KNZ77150.1 - 1.8 8.0 6.0 2.3 7.6 4.2 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus PBP PF01161.15 KNZ77151.1 - 8.1e-20 71.1 0.3 1.2e-19 70.5 0.2 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RRM_1 PF00076.17 KNZ77152.1 - 1.2e-18 66.4 0.1 1.2e-18 66.4 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ77152.1 - 2e-15 56.5 0.5 3.3e-15 55.8 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ77152.1 - 1.8e-11 43.7 0.0 1.8e-11 43.7 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KNZ77152.1 - 0.018 14.8 0.2 0.045 13.6 0.1 1.7 1 1 0 1 1 1 0 RNA binding motif Usp PF00582.21 KNZ77152.1 - 0.098 12.8 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 Universal stress protein family Mito_carr PF00153.22 KNZ77153.1 - 1.2e-63 210.8 5.8 1.4e-22 79.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.24 KNZ77154.1 - 1.1e-41 142.1 0.2 2.1e-41 141.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ77154.1 - 3.3e-27 94.1 0.2 7.2e-27 93.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KNZ77154.1 - 0.011 15.5 0.2 0.029 14.1 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 KNZ77154.1 - 0.019 14.7 0.0 0.063 13.1 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KNZ77154.1 - 0.027 14.5 0.1 0.11 12.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 KNZ77154.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF3449 PF11931.3 KNZ77155.1 - 4.5e-62 209.0 9.4 1.1e-30 106.5 0.0 2.9 4 0 0 4 4 4 2 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 KNZ77155.1 - 5.4e-08 32.2 0.1 1.7e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain Syja_N PF02383.13 KNZ77156.1 - 2.5e-75 253.2 0.0 3.4e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 KNZ77156.1 - 7.8e-29 101.3 0.0 1.5e-28 100.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SseB_C PF14581.1 KNZ77156.1 - 0.17 11.7 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 SseB protein C-terminal domain Erv26 PF04148.8 KNZ77157.1 - 1e-60 204.7 12.6 1.2e-60 204.4 8.7 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Snf7 PF03357.16 KNZ77158.1 - 6.1e-18 64.7 15.0 7.9e-18 64.4 10.4 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 KNZ77158.1 - 0.014 14.8 3.8 0.024 14.0 2.6 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway MMR_HSR1 PF01926.18 KNZ77160.1 - 1.1e-19 70.4 0.2 3.1e-14 52.9 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KNZ77160.1 - 3.2e-08 32.9 0.1 1.6e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 KNZ77160.1 - 3e-06 26.7 0.0 0.00032 20.1 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KNZ77160.1 - 0.00012 21.9 0.3 0.12 12.1 0.1 2.8 2 1 0 2 2 2 2 Dynamin family DUF258 PF03193.11 KNZ77160.1 - 0.00014 21.1 0.1 0.00025 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KNZ77160.1 - 0.0011 19.3 0.1 0.59 10.6 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein ArgK PF03308.11 KNZ77160.1 - 0.0083 14.9 0.1 0.02 13.7 0.0 1.6 2 0 0 2 2 2 1 ArgK protein PduV-EutP PF10662.4 KNZ77160.1 - 0.04 13.4 0.0 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KNZ77160.1 - 0.064 12.7 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KNZ77160.1 - 0.083 12.8 0.3 3.3 7.6 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 KNZ77160.1 - 0.099 12.3 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 KNZ77160.1 - 0.1 11.6 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 AIG1 family Abhydrolase_1 PF00561.15 KNZ77161.1 - 2.1e-18 66.7 0.1 2.2e-15 56.8 0.1 2.5 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KNZ77161.1 - 1e-10 41.9 0.6 1.1e-09 38.5 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KNZ77161.1 - 0.00035 20.0 0.0 0.00061 19.2 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KNZ77161.1 - 0.0049 16.6 0.0 0.053 13.2 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family zf-H2C2_2 PF13465.1 KNZ77162.1 - 5.5e-08 32.7 9.2 2.1e-07 30.9 0.1 4.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 KNZ77162.1 - 2.7e-07 30.5 18.3 9.6e-05 22.5 0.3 4.8 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KNZ77162.1 - 4.1e-05 23.3 1.6 0.35 10.8 0.0 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KNZ77162.1 - 0.00068 19.7 15.9 0.0098 16.1 0.2 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-Di19 PF05605.7 KNZ77162.1 - 0.017 15.2 6.2 0.46 10.6 0.6 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KNZ77162.1 - 0.024 14.8 4.8 2.7 8.3 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KNZ77162.1 - 0.59 10.3 3.9 7.1 6.9 0.0 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Snf7 PF03357.16 KNZ77163.1 - 3.4e-44 150.2 13.7 3.8e-44 150.0 9.5 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.15 KNZ77163.1 - 0.02 14.6 11.3 0.13 12.0 0.0 3.3 2 1 0 3 3 3 0 Prefoldin subunit NPV_P10 PF05531.7 KNZ77163.1 - 0.026 14.7 5.9 1.9 8.7 0.2 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.3 KNZ77163.1 - 0.15 11.8 3.6 0.66 9.7 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) FlaC_arch PF05377.6 KNZ77163.1 - 0.16 11.8 5.0 0.35 10.7 0.1 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Mnd1 PF03962.10 KNZ77163.1 - 0.5 10.0 13.0 12 5.5 9.0 2.1 1 1 0 1 1 1 0 Mnd1 family FlxA PF14282.1 KNZ77163.1 - 1.2 9.1 9.6 5.7 6.9 6.8 2.0 1 1 0 1 1 1 0 FlxA-like protein Uds1 PF15456.1 KNZ77163.1 - 1.9 8.4 9.4 1.1 9.2 2.8 2.2 1 1 1 2 2 2 0 Up-regulated During Septation DUF342 PF03961.8 KNZ77163.1 - 2.1 6.6 9.3 0.38 9.1 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) BLOC1_2 PF10046.4 KNZ77163.1 - 2.2 8.4 13.9 12 6.1 3.8 3.5 1 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HeLo PF14479.1 KNZ77163.1 - 2.4 7.8 9.2 4.4 6.9 0.3 2.1 1 1 1 2 2 2 0 Prion-inhibition and propagation Phage_GP20 PF06810.6 KNZ77163.1 - 3.2 7.1 15.3 24 4.3 8.5 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Aldedh PF00171.17 KNZ77164.1 - 4.1e-135 450.6 0.9 8.9e-119 396.8 0.2 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 KNZ77164.1 - 2.6e-06 26.4 0.0 5.9e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) RCC1 PF00415.13 KNZ77165.1 - 9.7e-52 172.9 17.7 6.8e-09 35.8 0.8 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KNZ77165.1 - 6.7e-36 121.1 48.6 1.3e-07 31.0 0.2 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 KNZ77165.1 - 0.13 11.8 0.0 4.7 6.7 0.0 2.7 2 0 0 2 2 2 0 Putative carbohydrate binding domain SPASM PF13186.1 KNZ77165.1 - 0.16 12.3 0.0 19 5.7 0.0 2.7 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain 2OG-FeII_Oxy PF03171.15 KNZ77167.1 - 2.3e-19 69.5 0.0 3.4e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BTB PF00651.26 KNZ77169.1 - 3.3e-07 30.2 0.0 1e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Spermine_synth PF01564.12 KNZ77170.1 - 2.6e-06 26.5 0.0 4.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 KNZ77170.1 - 0.038 14.0 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain p25-alpha PF05517.7 KNZ77171.1 - 0.039 14.2 0.0 0.066 13.4 0.0 1.3 1 0 0 1 1 1 0 p25-alpha GTP_cyclohydro2 PF00925.15 KNZ77172.1 - 2e-58 196.3 0.0 2.8e-53 179.6 0.0 2.2 2 0 0 2 2 2 2 GTP cyclohydrolase II Glyco_hydro_17 PF00332.13 KNZ77173.1 - 1.3e-11 44.1 3.4 1.6e-10 40.5 0.2 2.2 1 1 0 2 2 2 2 Glycosyl hydrolases family 17 DUF3552 PF12072.3 KNZ77173.1 - 0.085 12.0 1.1 0.26 10.4 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Sex_peptide PF08138.6 KNZ77173.1 - 0.13 12.0 0.6 0.27 11.0 0.4 1.5 1 0 0 1 1 1 0 Sex peptide (SP) family Vps5 PF09325.5 KNZ77174.1 - 2.4e-19 69.5 2.7 3.6e-19 68.9 1.9 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KNZ77174.1 - 1.4e-10 40.9 0.4 4.2e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 PX domain Phage_GP20 PF06810.6 KNZ77174.1 - 0.11 11.9 3.2 0.21 10.9 2.2 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4200 PF13863.1 KNZ77174.1 - 1.2 9.1 8.0 0.33 10.9 3.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Peptidase_M24 PF00557.19 KNZ77175.1 - 7.1e-13 48.6 0.0 1.5e-12 47.5 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 Pex14_N PF04695.8 KNZ77176.1 - 1.1e-08 35.2 0.0 1.1e-08 35.2 0.0 3.0 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Alpha-amylase_C PF02806.13 KNZ77177.1 - 1.6e-18 66.5 0.1 6.1e-18 64.7 0.0 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 KNZ77177.1 - 4.6e-17 62.3 0.0 8.8e-13 48.3 0.0 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 KNZ77177.1 - 1.3e-16 60.3 0.0 3.1e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Iso_dh PF00180.15 KNZ77178.1 - 1.5e-121 405.5 0.0 1.8e-121 405.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NOB1_Zn_bind PF08772.6 KNZ77179.1 - 7.9e-21 73.6 0.2 1.7e-20 72.6 0.1 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.1 KNZ77179.1 - 0.58 9.4 3.9 1.3 8.3 2.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain P21-Arc PF04062.9 KNZ77180.1 - 2e-77 258.8 0.0 2.3e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Ion_trans PF00520.26 KNZ77181.1 - 0.11 11.7 21.3 0.13 11.4 11.8 2.9 2 1 0 2 2 2 0 Ion transport protein Sld5 PF05916.6 KNZ77182.1 - 2.2e-17 63.3 0.1 3.3e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein DUF3635 PF12330.3 KNZ77183.1 - 7.4e-19 67.6 0.1 1.5e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Pkinase PF00069.20 KNZ77183.1 - 0.018 14.2 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Roughex PF06020.6 KNZ77183.1 - 0.17 10.5 2.2 0.33 9.5 1.5 1.4 1 0 0 1 1 1 0 Drosophila roughex protein SKN1 PF03935.10 KNZ77184.1 - 1.5e-187 623.7 1.8 1.8e-187 623.5 1.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) F-box PF00646.28 KNZ77185.1 - 8.1e-07 28.5 1.6 8.1e-07 28.5 1.1 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KNZ77185.1 - 2.2e-05 24.0 0.6 2.2e-05 24.0 0.4 2.3 2 0 0 2 2 2 1 F-box-like zf-C2H2 PF00096.21 KNZ77186.1 - 2.5e-08 33.7 23.0 0.00046 20.3 3.8 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KNZ77186.1 - 1.3e-07 31.5 13.1 0.0009 19.4 0.9 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KNZ77186.1 - 0.00054 20.0 19.8 0.06 13.7 2.0 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger UCH PF00443.24 KNZ77187.1 - 1.2e-52 178.6 0.0 1.7e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNZ77187.1 - 4.6e-23 82.0 0.0 8e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KNZ77187.1 - 0.0031 16.8 2.2 0.033 13.4 1.5 2.4 1 1 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase DZR PF12773.2 KNZ77187.1 - 0.58 10.0 3.4 8 6.3 0.0 3.0 3 0 0 3 3 3 0 Double zinc ribbon PP2C PF00481.16 KNZ77188.1 - 4.4e-27 95.0 0.0 7.3e-24 84.5 0.0 2.3 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KNZ77188.1 - 2.7e-10 40.0 0.0 8.4e-09 35.1 0.0 2.6 1 1 0 1 1 1 1 Protein phosphatase 2C ACT_7 PF13840.1 KNZ77190.1 - 9.1e-14 50.7 0.3 1.4e-12 46.8 0.0 2.4 1 1 1 2 2 2 2 ACT domain adh_short PF00106.20 KNZ77192.1 - 3.3e-27 95.4 0.1 1.1e-26 93.7 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ77192.1 - 9.1e-12 45.0 0.1 2.1e-10 40.5 0.1 2.2 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KNZ77192.1 - 7.5e-07 29.1 0.0 1e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KNZ77192.1 - 0.00088 19.3 0.0 0.0032 17.5 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KNZ77192.1 - 0.097 12.0 0.2 0.39 10.0 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RNA_polI_A14 PF08203.6 KNZ77193.1 - 0.03 14.5 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Ubiq_cyt_C_chap PF03981.7 KNZ77193.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.0 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone CAP PF00188.21 KNZ77195.1 - 2e-08 34.7 0.5 2.4e-08 34.5 0.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Prefoldin_2 PF01920.15 KNZ77196.1 - 4e-20 71.5 1.3 5.2e-20 71.1 0.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Cob_adeno_trans PF01923.13 KNZ77196.1 - 0.025 14.3 0.2 0.03 14.1 0.2 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Tropomyosin_1 PF12718.2 KNZ77196.1 - 0.033 14.0 3.6 0.33 10.8 1.1 2.1 2 0 0 2 2 2 0 Tropomyosin like Syntaxin-6_N PF09177.6 KNZ77196.1 - 0.11 12.8 1.1 2.7 8.4 0.2 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DASH_Dad3 PF08656.5 KNZ77196.1 - 0.35 10.5 2.3 0.46 10.2 0.8 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF812 PF05667.6 KNZ77196.1 - 0.6 8.5 4.4 0.21 10.0 1.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) IncA PF04156.9 KNZ77196.1 - 3 7.4 7.4 25 4.3 5.1 1.9 1 1 0 1 1 1 0 IncA protein FlxA PF14282.1 KNZ77196.1 - 3.1 7.7 6.3 12 5.8 2.3 2.2 2 0 0 2 2 2 0 FlxA-like protein Fer4 PF00037.22 KNZ77197.1 - 5.9e-14 50.9 17.4 1.7e-08 33.6 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KNZ77197.1 - 5.3e-12 45.9 9.9 8.3e-12 45.3 6.8 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 KNZ77197.1 - 3.4e-10 40.5 7.1 7.3e-05 23.4 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 KNZ77197.1 - 6.3e-10 38.6 21.8 3.1e-08 33.2 8.1 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KNZ77197.1 - 1.3e-09 38.1 9.1 2.4e-09 37.2 6.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 KNZ77197.1 - 4.1e-09 36.1 32.4 7.8e-06 25.6 8.7 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.1 KNZ77197.1 - 2.2e-08 34.0 19.4 2.7e-05 24.1 8.2 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KNZ77197.1 - 2.6e-08 33.2 15.2 7.2e-05 22.4 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KNZ77197.1 - 7.9e-08 31.8 18.0 0.00075 19.2 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 KNZ77197.1 - 4.2e-07 30.2 25.9 0.00015 22.0 6.8 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 KNZ77197.1 - 2.5e-06 27.3 12.0 0.00065 19.8 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 KNZ77197.1 - 2.9e-05 24.4 9.5 0.022 15.1 0.6 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 KNZ77197.1 - 0.00043 20.6 12.7 0.057 13.8 0.7 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 KNZ77197.1 - 0.0022 18.4 11.8 0.18 12.4 0.8 2.6 2 1 0 2 2 2 2 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.5 KNZ77197.1 - 0.035 14.2 4.1 0.23 11.6 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_3 PF12798.2 KNZ77197.1 - 0.044 14.3 18.1 0.08 13.5 3.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain CASP_C PF08172.7 KNZ77198.1 - 0.07 12.1 0.2 0.14 11.1 0.1 1.7 1 1 0 1 1 1 0 CASP C terminal DUF465 PF04325.8 KNZ77198.1 - 0.34 10.6 3.8 0.99 9.1 2.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF465) bZIP_1 PF00170.16 KNZ77198.1 - 0.36 10.8 2.8 0.81 9.6 1.9 1.5 1 0 0 1 1 1 0 bZIP transcription factor GRIM-19 PF06212.7 KNZ77199.1 - 2.9e-29 101.3 0.0 3.4e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein HMG_box_2 PF09011.5 KNZ77200.1 - 2.1e-16 60.0 11.4 8.6e-08 32.4 2.4 2.5 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 KNZ77200.1 - 6.6e-14 51.9 16.4 9.8e-07 28.9 4.4 3.3 2 1 0 2 2 2 2 HMG (high mobility group) box Acetyltransf_1 PF00583.19 KNZ77201.1 - 2.8e-05 24.0 0.0 5.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KNZ77201.1 - 0.0008 19.5 0.1 0.0013 18.7 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 KNZ77201.1 - 0.048 14.2 0.0 2.8 8.5 0.0 2.4 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain PPR_2 PF13041.1 KNZ77202.1 - 2.7e-39 132.8 2.8 2.5e-11 43.3 0.0 11.0 8 2 3 11 11 11 5 PPR repeat family PPR PF01535.15 KNZ77202.1 - 1.2e-32 109.6 5.9 5.8e-05 22.8 0.0 13.6 15 0 0 15 15 15 7 PPR repeat PPR_3 PF13812.1 KNZ77202.1 - 2.4e-31 105.3 17.1 6.1e-07 29.2 0.0 14.2 15 0 0 15 15 14 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 KNZ77202.1 - 6.5e-22 76.7 5.2 5.6e-06 25.7 0.0 9.3 10 0 0 10 10 10 3 PPR repeat TPR_14 PF13428.1 KNZ77202.1 - 3.4e-06 27.1 7.8 18 6.3 0.0 7.3 5 2 1 6 6 6 0 Tetratricopeptide repeat ATP13 PF12921.2 KNZ77202.1 - 0.00061 19.1 0.0 0.045 13.0 0.0 3.9 5 1 0 5 5 5 1 Mitochondrial ATPase expression ECSIT PF06239.6 KNZ77202.1 - 0.0055 15.6 0.1 0.21 10.4 0.0 3.1 3 0 0 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_16 PF13432.1 KNZ77202.1 - 0.0085 16.7 4.0 5.1 7.9 0.0 5.5 7 1 0 7 7 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ77202.1 - 0.047 13.8 0.1 1e+02 3.4 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ77202.1 - 0.12 12.8 6.6 1.2 9.7 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KNZ77202.1 - 0.17 12.4 13.1 0.12 12.9 1.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Velvet PF11754.3 KNZ77203.1 - 2.9e-47 160.9 0.0 2.8e-46 157.7 0.0 2.1 1 1 0 1 1 1 1 Velvet factor ArfGap PF01412.13 KNZ77204.1 - 4.6e-33 113.4 0.4 8.2e-33 112.6 0.3 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Carboxyl_trans PF01039.17 KNZ77205.1 - 3.9e-139 464.1 0.0 6.8e-139 463.3 0.0 1.3 1 1 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 KNZ77205.1 - 1.2e-05 24.6 0.2 0.023 13.9 0.0 2.5 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) HATPase_c_3 PF13589.1 KNZ77206.1 - 4.3e-09 36.1 0.0 9.1e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 KNZ77206.1 - 2.3e-08 33.5 0.0 5.1e-06 25.9 0.0 2.9 3 0 0 3 3 3 2 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 KNZ77206.1 - 1.6e-06 27.7 0.0 3.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KNZ77206.1 - 5.3e-06 26.0 0.0 4.8e-05 23.0 0.0 2.5 1 1 0 1 1 1 1 MutL C terminal dimerisation domain SBDS PF01172.13 KNZ77207.1 - 1.9e-19 69.2 0.1 2.3e-19 68.9 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF1546 PF07571.8 KNZ77208.1 - 1.3e-17 63.7 0.0 3.3e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 KNZ77208.1 - 8.9e-16 57.5 2.3 5.5e-07 29.4 0.2 2.6 1 1 1 2 2 2 2 TATA box binding protein associated factor (TAF) HEAT_EZ PF13513.1 KNZ77208.1 - 0.035 14.6 10.8 1 9.9 0.0 5.3 4 2 2 6 6 6 0 HEAT-like repeat Histone PF00125.19 KNZ77208.1 - 0.099 12.7 0.3 0.39 10.8 0.0 2.2 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Phostensin_N PF13916.1 KNZ77208.1 - 0.22 11.5 5.7 0.17 11.9 2.0 2.1 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal RIX1 PF08167.7 KNZ77208.1 - 0.47 10.1 4.4 1.5 8.4 3.0 2.0 1 1 0 1 1 1 0 rRNA processing/ribosome biogenesis UBN2_3 PF14244.1 KNZ77209.1 - 0.0094 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Mnd1 PF03962.10 KNZ77210.1 - 0.0012 18.5 2.7 0.0014 18.3 1.9 1.2 1 0 0 1 1 1 1 Mnd1 family DUF1664 PF07889.7 KNZ77210.1 - 0.016 15.0 1.9 0.025 14.3 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FliD_N PF02465.13 KNZ77210.1 - 0.019 15.3 2.6 0.041 14.2 1.8 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus GEMIN8 PF15348.1 KNZ77210.1 - 0.029 14.4 1.8 0.038 14.0 1.3 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 IncA PF04156.9 KNZ77210.1 - 2.9 7.4 5.6 1.4 8.4 2.0 1.7 1 1 1 2 2 2 0 IncA protein Pkinase PF00069.20 KNZ77211.1 - 9.4e-13 47.8 0.0 1.5e-10 40.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77211.1 - 0.00029 20.0 0.0 0.0058 15.7 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 KNZ77211.1 - 0.03 13.1 0.1 0.05 12.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PIF1 PF05970.9 KNZ77213.1 - 3.6e-51 174.2 0.1 4.3e-51 173.9 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ77213.1 - 0.0036 16.9 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KNZ77213.1 - 0.096 12.5 0.0 0.28 11.0 0.0 1.7 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit PIF1 PF05970.9 KNZ77214.1 - 6.6e-30 104.2 0.5 7.6e-30 104.0 0.4 1.1 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 KNZ77214.1 - 0.0062 16.6 0.0 0.018 15.1 0.0 1.8 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain SNF5 PF04855.7 KNZ77215.1 - 4.9e-60 203.0 0.0 8e-60 202.3 0.0 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 AFG1_ATPase PF03969.11 KNZ77216.1 - 1.8e-87 293.5 0.0 6.3e-84 281.8 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 KNZ77216.1 - 7.1e-05 22.8 0.1 0.053 13.5 0.0 2.8 2 1 1 3 3 3 2 AAA ATPase domain AAA PF00004.24 KNZ77216.1 - 0.0004 20.6 0.0 0.0015 18.7 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KNZ77216.1 - 0.0024 17.9 0.0 0.021 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KNZ77216.1 - 0.042 13.5 0.0 0.1 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.13 KNZ77216.1 - 0.11 12.1 0.1 0.29 10.7 0.1 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein Arch_ATPase PF01637.13 KNZ77216.1 - 0.19 11.3 0.1 9.6 5.8 0.0 2.7 3 0 0 3 3 3 0 Archaeal ATPase UreF PF01730.11 KNZ77217.1 - 8.7e-13 48.6 0.1 1.5e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 UreF JAB PF01398.16 KNZ77218.1 - 8.8e-18 64.1 0.2 2.3e-17 62.7 0.1 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KNZ77218.1 - 2.4e-13 50.1 0.1 4.7e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Tom7 PF08038.7 KNZ77219.1 - 4.4e-11 42.0 0.3 6.7e-11 41.4 0.2 1.3 1 0 0 1 1 1 1 TOM7 family Tmemb_14 PF03647.8 KNZ77219.1 - 0.034 14.5 0.0 0.039 14.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane proteins 14C zf-C3HC4_2 PF13923.1 KNZ77220.1 - 3e-07 30.3 16.8 3e-07 30.3 11.7 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ77220.1 - 3.2e-05 23.5 20.7 0.00014 21.4 8.9 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KNZ77220.1 - 6.5e-05 22.5 20.5 0.00012 21.7 7.8 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ77220.1 - 0.00043 20.0 16.0 0.00043 20.0 11.1 3.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KNZ77220.1 - 0.00077 19.0 14.5 0.00077 19.0 10.0 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 KNZ77220.1 - 0.0011 19.0 1.8 3.7 7.7 0.0 3.6 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding ADSL_C PF10397.4 KNZ77220.1 - 1.2 9.1 3.7 9.4 6.3 0.3 2.9 3 1 0 3 3 3 0 Adenylosuccinate lyase C-terminus zf-C3HC4_4 PF15227.1 KNZ77220.1 - 3.6 7.5 18.5 5.1 7.0 8.5 3.4 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KNZ77220.1 - 7.2 6.4 17.9 0.14 11.9 6.7 2.3 3 0 0 3 3 3 0 zf-RING of BARD1-type protein Glyco_hydro_3 PF00933.16 KNZ77221.1 - 4.9e-76 255.5 0.0 8e-76 254.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KNZ77221.1 - 8e-59 198.9 0.0 1.4e-57 194.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KNZ77221.1 - 2e-22 78.9 0.0 5.9e-22 77.3 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KNZ77221.1 - 0.00012 21.7 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 PA14 domain SET PF00856.23 KNZ77222.1 - 0.0015 18.8 0.0 2 8.7 0.0 2.2 2 0 0 2 2 2 2 SET domain Imm19 PF15567.1 KNZ77222.1 - 0.13 12.2 0.1 0.47 10.4 0.0 2.0 2 1 0 2 2 2 0 Immunity protein 19 7kD_DNA_binding PF02294.13 KNZ77223.1 - 0.025 14.2 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 7kD DNA-binding domain DUF3958 PF13125.1 KNZ77223.1 - 0.061 13.2 0.0 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Sugar_tr PF00083.19 KNZ77224.1 - 2.1e-86 290.3 18.4 2.6e-86 289.9 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ77224.1 - 2e-34 118.8 43.9 1.1e-31 109.8 17.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KNZ77224.1 - 9e-08 30.9 20.9 0.00035 19.1 2.3 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 KNZ77224.1 - 2.7e-06 25.9 1.9 2.7e-06 25.9 1.3 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KNZ77224.1 - 0.0045 15.1 0.4 0.0045 15.1 0.3 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector DUF1129 PF06570.6 KNZ77224.1 - 0.026 13.8 0.3 0.056 12.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Glyco_hydro_18 PF00704.23 KNZ77225.1 - 1.3e-65 222.1 4.3 1.9e-65 221.5 2.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_M28 PF04389.12 KNZ77226.1 - 7.2e-29 100.7 0.0 1.5e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KNZ77226.1 - 2e-07 30.7 0.0 1e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 KNZ77226.1 - 0.094 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Vac14_Fig4_bd PF11916.3 KNZ77227.1 - 4e-81 270.5 7.7 7e-81 269.7 5.4 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KNZ77227.1 - 6.3e-42 141.9 0.1 7.9e-38 128.7 0.0 3.3 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KNZ77227.1 - 3e-10 39.3 0.3 0.0034 17.3 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 KNZ77227.1 - 0.00022 21.5 0.2 1.4 9.4 0.0 5.5 7 0 0 7 7 7 1 HEAT-like repeat MMS19_C PF12460.3 KNZ77227.1 - 0.00026 19.8 0.5 0.17 10.5 0.0 3.3 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal Cnd1 PF12717.2 KNZ77227.1 - 0.0049 16.7 5.0 1.6 8.5 0.0 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF2120 PF09893.4 KNZ77227.1 - 0.077 12.9 0.2 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Y_phosphatase3 PF13350.1 KNZ77228.1 - 1e-48 165.6 0.0 1.4e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KNZ77228.1 - 9.4e-10 38.4 0.0 2.1e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KNZ77228.1 - 0.00096 18.5 0.0 0.002 17.5 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KNZ77228.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 KNZ77228.1 - 0.062 12.6 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MCM PF00493.18 KNZ77229.1 - 2.1e-138 460.6 0.4 3.2e-138 460.0 0.3 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KNZ77229.1 - 1.8e-23 83.3 0.0 4.7e-23 81.9 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KNZ77229.1 - 6.9e-08 31.8 0.0 5.8e-07 28.8 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KNZ77229.1 - 0.00082 18.9 0.1 0.0042 16.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KNZ77229.1 - 0.0035 16.8 0.0 0.0083 15.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 KNZ77229.1 - 0.025 14.3 0.0 0.057 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) APH PF01636.18 KNZ77230.1 - 1.6e-07 31.3 0.9 5.5e-07 29.5 0.6 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ77230.1 - 3.2e-06 26.8 0.0 5.3e-06 26.1 0.0 1.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 KNZ77230.1 - 0.0018 17.4 0.0 0.074 12.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.17 KNZ77230.1 - 0.021 14.1 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 KNZ77230.1 - 0.084 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_7C PF02709.9 KNZ77230.1 - 0.098 12.1 0.2 0.16 11.4 0.2 1.3 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase LNS2 PF08235.8 KNZ77232.1 - 8.7e-70 233.3 0.0 1.3e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KNZ77232.1 - 1.9e-26 91.8 0.2 1.3e-23 82.7 0.0 2.8 2 1 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 KNZ77232.1 - 0.077 12.3 0.2 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Complex1_LYR PF05347.10 KNZ77233.1 - 5.1e-09 35.7 1.2 8.7e-09 35.0 0.8 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KNZ77233.1 - 1.3e-07 31.6 0.6 2.1e-07 31.0 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like RRN3 PF05327.6 KNZ77234.1 - 4e-143 477.5 0.0 1.5e-80 270.9 0.0 2.0 1 1 1 2 2 2 2 RNA polymerase I specific transcription initiation factor RRN3 Ank_2 PF12796.2 KNZ77235.1 - 3.3e-22 78.6 10.6 1.1e-12 48.1 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ77235.1 - 7.9e-15 53.8 1.2 1.4e-05 24.6 0.0 4.6 3 2 1 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 KNZ77235.1 - 3.9e-11 42.0 1.9 0.00059 19.8 0.1 4.4 3 2 1 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KNZ77235.1 - 2.4e-10 40.3 1.2 0.0045 17.2 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KNZ77235.1 - 3.1e-10 40.2 0.1 0.00051 20.4 0.0 3.7 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Rib_hydrolayse PF02267.12 KNZ77236.1 - 0.0045 16.3 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosyl cyclase IU_nuc_hydro PF01156.14 KNZ77237.1 - 1.3e-71 241.4 0.0 1.9e-71 240.8 0.0 1.2 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Peptidase_S28 PF05577.7 KNZ77238.1 - 5.1e-51 173.6 0.1 7.4e-38 130.2 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 KNZ77238.1 - 0.00096 19.0 0.1 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ77238.1 - 0.0043 16.3 0.0 0.0085 15.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KNZ77238.1 - 0.06 13.1 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_M16_C PF05193.16 KNZ77239.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase M16 inactive domain Phage_integrase PF00589.17 KNZ77240.1 - 0.0082 15.8 0.0 0.026 14.1 0.0 1.7 2 0 0 2 2 2 1 Phage integrase family zf-CCHC PF00098.18 KNZ77241.1 - 1.3 9.0 9.3 0.21 11.6 3.5 1.9 2 0 0 2 2 2 0 Zinc knuckle Chromo PF00385.19 KNZ77242.1 - 9.7e-18 63.6 0.1 1.2e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SF3a60_bindingd PF12108.3 KNZ77242.1 - 0.0091 15.5 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain Mtf2_C PF14061.1 KNZ77242.1 - 0.047 13.5 0.2 0.064 13.1 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Tudor-knot PF11717.3 KNZ77242.1 - 0.2 11.3 0.9 0.27 10.9 0.7 1.3 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Pyr_redox_3 PF13738.1 KNZ77243.1 - 1e-21 77.9 0.0 1.6e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KNZ77243.1 - 2e-15 55.9 0.0 4e-15 55.0 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KNZ77243.1 - 3.6e-11 42.5 0.0 1.7e-08 33.8 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KNZ77243.1 - 4.2e-10 39.4 1.0 1.6e-09 37.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KNZ77243.1 - 6.3e-08 32.7 0.0 2.9e-05 24.0 0.0 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNZ77243.1 - 7.4e-06 25.8 0.8 0.0012 18.6 0.1 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KNZ77243.1 - 1.3e-05 24.3 0.1 0.014 14.3 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KNZ77243.1 - 9.3e-05 22.7 0.4 0.58 10.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KNZ77243.1 - 0.011 14.9 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 KNZ77243.1 - 0.016 14.2 0.2 0.039 13.0 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 KNZ77243.1 - 0.025 13.5 0.0 0.057 12.3 0.0 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KNZ77243.1 - 0.041 12.7 0.1 8.5 5.1 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KNZ77243.1 - 0.059 12.2 0.1 0.34 9.6 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 KNZ77243.1 - 0.11 12.8 0.0 27 5.0 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding HI0933_like PF03486.9 KNZ77243.1 - 0.38 9.1 2.2 0.33 9.3 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Cellulase PF00150.13 KNZ77244.1 - 5.3e-44 150.5 0.0 7.4e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2183 PF09949.4 KNZ77245.1 - 8.9e-21 73.7 0.0 3.7e-20 71.7 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Pkinase PF00069.20 KNZ77246.1 - 2.7e-06 26.7 0.0 4.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KNZ77246.1 - 0.002 17.8 5.2 0.15 11.8 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KNZ77246.1 - 0.0032 16.5 0.0 0.005 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KNZ77246.1 - 0.011 14.8 0.3 0.037 13.0 0.1 2.0 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Opi1 PF08618.5 KNZ77247.1 - 2.1e-60 204.8 10.6 4.9e-49 167.4 4.1 3.1 1 1 1 2 2 2 2 Transcription factor Opi1 Perilipin PF03036.11 KNZ77247.1 - 0.0043 15.9 0.0 0.008 15.0 0.0 1.4 1 0 0 1 1 1 1 Perilipin family DUF1199 PF06712.6 KNZ77247.1 - 0.013 15.2 0.1 0.055 13.2 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) Kinesin PF00225.18 KNZ77248.1 - 7.3e-99 330.6 0.1 4.4e-98 328.0 0.1 2.0 1 1 0 1 1 1 1 Kinesin motor domain ATG16 PF08614.6 KNZ77248.1 - 0.0049 16.7 13.2 0.0049 16.7 9.1 2.6 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Atg14 PF10186.4 KNZ77248.1 - 0.033 13.1 21.6 0.15 10.9 13.7 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Macoilin PF09726.4 KNZ77248.1 - 0.041 12.1 16.9 0.065 11.5 11.7 1.2 1 0 0 1 1 1 0 Transmembrane protein ThiS PF02597.15 KNZ77248.1 - 0.063 13.7 3.0 1.5 9.3 0.1 4.0 4 0 0 4 4 4 0 ThiS family ADIP PF11559.3 KNZ77248.1 - 0.11 12.4 27.7 0.068 13.0 8.7 3.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding ERM PF00769.14 KNZ77248.1 - 0.43 10.0 26.3 0.75 9.2 18.2 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FH2 PF02181.18 KNZ77248.1 - 0.45 9.3 12.8 0.09 11.6 3.6 2.4 2 1 1 3 3 3 0 Formin Homology 2 Domain IncA PF04156.9 KNZ77248.1 - 0.65 9.5 25.9 1.4 8.4 13.3 2.5 1 1 1 2 2 2 0 IncA protein DUF1664 PF07889.7 KNZ77248.1 - 0.77 9.5 10.2 0.19 11.5 3.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 KNZ77248.1 - 1.3 7.6 20.1 1.2 7.7 10.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 KNZ77248.1 - 3.5 6.7 15.1 0.26 10.4 3.1 3.0 2 1 1 3 3 3 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 KNZ77248.1 - 4.7 4.9 9.4 7 4.3 6.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family p450 PF00067.17 KNZ77249.1 - 1.1e-65 221.9 0.0 1.3e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAP3 PF10236.4 KNZ77251.1 - 9.3e-61 205.4 0.0 1.3e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Exo_endo_phos PF03372.18 KNZ77251.1 - 1.3e-11 44.9 0.0 2.6e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KNZ77251.1 - 3.8e-08 32.9 0.0 1.2e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 KNZ77251.1 - 6.6e-06 25.9 0.1 1.3e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 GRF zinc finger AAA_16 PF13191.1 KNZ77251.1 - 7e-05 22.8 0.0 0.00019 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 KNZ77251.1 - 0.0034 16.8 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KNZ77251.1 - 0.0039 16.6 0.0 0.0089 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KNZ77251.1 - 0.0044 16.7 0.0 0.013 15.1 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 KNZ77251.1 - 0.038 13.4 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 KNZ77251.1 - 0.044 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ArgK PF03308.11 KNZ77251.1 - 0.1 11.3 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 ArgK protein RNA_helicase PF00910.17 KNZ77251.1 - 0.16 12.1 0.1 3.1 8.0 0.0 3.0 2 1 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 KNZ77251.1 - 0.17 11.7 0.0 0.49 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Amino_oxidase PF01593.19 KNZ77252.1 - 9.5e-70 235.8 0.1 5.8e-54 183.8 0.0 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KNZ77252.1 - 1.1e-10 41.3 0.2 2.9e-10 40.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KNZ77252.1 - 5.2e-07 28.9 0.1 0.0012 17.8 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KNZ77252.1 - 8.9e-06 24.9 0.3 0.00014 21.0 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KNZ77252.1 - 9.4e-05 21.6 0.6 0.0057 15.7 0.8 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KNZ77252.1 - 0.0001 22.5 0.3 0.0092 16.3 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNZ77252.1 - 0.00041 20.4 1.2 0.0051 16.8 0.3 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KNZ77252.1 - 0.00051 18.9 0.3 0.00086 18.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 KNZ77252.1 - 0.0079 15.7 0.2 0.033 13.7 0.2 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 KNZ77252.1 - 0.014 15.4 0.1 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KNZ77252.1 - 0.02 13.3 0.1 0.1 11.0 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 KNZ77252.1 - 0.034 14.0 0.1 0.16 11.7 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 KNZ77252.1 - 0.1 12.7 0.1 0.26 11.3 0.0 1.7 2 0 0 2 2 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain GIDA PF01134.17 KNZ77252.1 - 0.32 9.7 1.2 0.41 9.4 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A UQ_con PF00179.21 KNZ77253.1 - 2e-17 62.9 0.1 2.2e-17 62.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KNZ77253.1 - 0.0017 18.2 0.1 0.002 17.9 0.0 1.3 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KNZ77253.1 - 0.034 13.8 0.1 0.04 13.5 0.1 1.2 1 0 0 1 1 1 0 UEV domain VHS PF00790.14 KNZ77254.1 - 2.5e-31 108.1 0.3 4.9e-31 107.2 0.2 1.5 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 KNZ77254.1 - 4.6e-15 54.9 0.2 8.7e-15 54.0 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KNZ77254.1 - 3.1e-14 52.1 0.2 5.3e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KNZ77254.1 - 6.2e-14 51.1 0.1 1.2e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain GAT PF03127.9 KNZ77254.1 - 0.00024 21.0 1.0 0.00024 21.0 0.7 2.0 2 0 0 2 2 2 1 GAT domain UIM PF02809.15 KNZ77254.1 - 0.0005 19.4 0.9 0.0015 17.9 0.6 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif IRF-3 PF10401.4 KNZ77256.1 - 0.096 12.2 0.1 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Interferon-regulatory factor 3 Amino_oxidase PF01593.19 KNZ77258.1 - 6.2e-68 229.9 0.1 4.5e-51 174.3 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KNZ77258.1 - 3.9e-12 46.0 0.3 8.8e-12 44.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KNZ77258.1 - 9.7e-07 27.9 0.1 0.00078 18.4 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KNZ77258.1 - 0.00026 20.1 0.9 0.00042 19.4 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KNZ77258.1 - 0.00028 19.8 0.7 0.00043 19.2 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KNZ77258.1 - 0.0024 17.9 0.8 0.0058 16.7 0.6 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KNZ77258.1 - 0.0041 16.2 0.4 0.0077 15.3 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KNZ77258.1 - 0.011 16.1 0.7 0.025 14.9 0.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KNZ77258.1 - 0.022 14.8 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 KNZ77258.1 - 0.048 13.2 0.3 0.11 12.0 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 KNZ77258.1 - 0.056 11.8 0.1 0.12 10.8 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 KNZ77258.1 - 0.11 12.3 0.3 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KNZ77258.1 - 0.17 10.6 0.2 0.27 10.0 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Acetyltransf_3 PF13302.1 KNZ77259.1 - 1.3e-11 44.8 0.0 1.7e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ77259.1 - 4.2e-05 23.5 0.0 7.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ilar_coat PF01787.11 KNZ77259.1 - 0.071 12.6 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Ilarvirus coat protein zf-C2H2_jaz PF12171.3 KNZ77261.1 - 3.8e-10 39.5 3.0 7.2e-10 38.7 2.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KNZ77261.1 - 0.0095 16.0 0.3 0.015 15.3 0.2 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KNZ77261.1 - 0.034 14.3 1.3 0.061 13.5 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KNZ77261.1 - 0.056 13.8 0.5 0.16 12.3 0.4 1.8 1 1 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ77261.1 - 0.12 12.7 1.5 0.33 11.4 1.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger RNase_H PF00075.19 KNZ77262.1 - 1e-11 45.2 0.0 2e-11 44.3 0.0 1.5 1 1 0 1 1 1 1 RNase H Zn_Tnp_IS1595 PF12760.2 KNZ77263.1 - 0.054 13.3 1.9 0.093 12.5 1.3 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain TerY-C PF15616.1 KNZ77263.1 - 0.084 12.8 0.1 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_3 PF14369.1 KNZ77263.1 - 0.25 11.3 5.3 0.43 10.6 1.4 2.3 1 1 1 2 2 2 0 zinc-finger Asp_protease_2 PF13650.1 KNZ77266.1 - 7.1e-06 26.4 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ77266.1 - 0.0027 17.2 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Kelch_6 PF13964.1 KNZ77266.1 - 0.06 13.5 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Kelch motif eIF3g PF12353.3 KNZ77267.1 - 0.02 14.7 0.4 0.041 13.7 0.3 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G UBN2_2 PF14227.1 KNZ77267.1 - 0.027 13.9 0.4 0.097 12.2 0.3 1.8 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ77267.1 - 0.11 12.3 0.1 0.35 10.6 0.1 1.8 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type Acetyltransf_3 PF13302.1 KNZ77268.1 - 1.7e-10 41.2 0.0 2.2e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ77268.1 - 0.0012 18.7 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family zf-C2H2_jaz PF12171.3 KNZ77269.1 - 2.1e-10 40.4 3.3 3.9e-10 39.5 2.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KNZ77269.1 - 0.0045 17.0 0.3 0.0071 16.4 0.2 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KNZ77269.1 - 0.049 13.8 1.3 0.089 13.0 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KNZ77269.1 - 0.051 13.9 0.4 0.13 12.6 0.2 1.8 1 1 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ77269.1 - 0.18 12.1 1.4 0.53 10.7 1.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Cellulase PF00150.13 KNZ77270.1 - 4.4e-15 55.6 0.0 6.5e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Methyltransf_31 PF13847.1 KNZ77271.1 - 1.6e-27 95.9 0.0 2.9e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ77271.1 - 1.4e-19 70.3 0.0 3.5e-19 69.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ77271.1 - 1.1e-16 61.4 0.0 2.1e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNZ77271.1 - 1.3e-13 50.6 0.0 2.4e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KNZ77271.1 - 1.6e-13 50.9 0.0 4.7e-13 49.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ77271.1 - 1.1e-11 45.0 0.0 2.2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ77271.1 - 7.4e-11 42.1 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ77271.1 - 1.7e-10 40.8 0.0 2.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Rhodanese PF00581.15 KNZ77271.1 - 1.5e-09 38.1 0.0 4.9e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain MTS PF05175.9 KNZ77271.1 - 2e-06 27.3 0.0 3.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KNZ77271.1 - 3.2e-05 23.1 0.2 6.4e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 KNZ77271.1 - 9.6e-05 22.0 0.0 0.00042 19.9 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 KNZ77271.1 - 0.00048 19.4 0.0 0.0009 18.6 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_8 PF05148.10 KNZ77271.1 - 0.0092 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_24 PF13578.1 KNZ77271.1 - 0.011 16.5 0.0 0.032 15.0 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KNZ77271.1 - 0.024 13.6 0.0 0.1 11.5 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase UPF0020 PF01170.13 KNZ77271.1 - 0.037 13.6 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 HMG_box PF00505.14 KNZ77272.1 - 1.2e-13 51.1 0.1 2e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KNZ77272.1 - 0.013 15.8 0.2 0.03 14.6 0.1 1.7 1 1 0 1 1 1 0 HMG-box domain MAT_Alpha1 PF04769.7 KNZ77272.1 - 0.065 12.5 0.1 0.085 12.1 0.1 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 PAXIP1_C PF15364.1 KNZ77272.1 - 0.11 12.4 0.4 0.16 11.8 0.3 1.2 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Sugar_tr PF00083.19 KNZ77274.1 - 1.4e-18 66.7 22.7 1.7e-14 53.2 2.7 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 KNZ77274.1 - 4.2e-15 55.3 48.2 8.5e-08 31.2 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2583 PF10762.4 KNZ77274.1 - 0.034 14.2 0.5 0.14 12.2 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) Pyridox_oxidase PF01243.15 KNZ77275.1 - 0.00021 21.2 0.0 0.043 13.8 0.0 3.9 4 1 0 4 4 4 1 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.16 KNZ77275.1 - 0.0086 16.6 0.0 0.025 15.1 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KNZ77275.1 - 0.0086 16.1 0.0 0.11 12.6 0.0 2.2 1 1 1 2 2 2 1 Oxidoreductase FAD-binding domain Pkinase PF00069.20 KNZ77276.1 - 6.6e-47 159.8 0.0 8.2e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77276.1 - 6.5e-24 84.3 0.0 9.1e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ77276.1 - 0.00027 19.9 0.0 0.00086 18.3 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Cutinase PF01083.17 KNZ77277.1 - 8.1e-47 159.2 0.2 9.2e-47 159.0 0.1 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KNZ77277.1 - 0.00057 19.3 0.0 0.0007 19.0 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.3 KNZ77277.1 - 0.0027 17.1 0.3 0.005 16.2 0.1 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 KNZ77277.1 - 0.0037 16.8 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KNZ77277.1 - 0.004 16.9 0.1 0.0045 16.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.6 KNZ77277.1 - 0.0053 16.5 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_6 PF12697.2 KNZ77277.1 - 0.0056 16.5 0.2 0.0068 16.3 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KNZ77277.1 - 0.012 15.8 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain LIP PF03583.9 KNZ77277.1 - 0.035 13.2 0.3 0.045 12.9 0.2 1.2 1 0 0 1 1 1 0 Secretory lipase Abhydrolase_1 PF00561.15 KNZ77277.1 - 0.036 13.6 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_9 PF10081.4 KNZ77277.1 - 0.046 12.4 0.0 0.057 12.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family DLH PF01738.13 KNZ77284.1 - 1.2e-23 83.5 0.0 1.6e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KNZ77284.1 - 1.9e-05 24.4 0.0 6.8e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ77284.1 - 0.064 12.4 0.0 0.24 10.5 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KNZ77284.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_61 PF03443.9 KNZ77285.1 - 1.8e-60 204.4 0.9 2.4e-60 204.0 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KNZ77285.1 - 7.5e-13 47.9 11.8 7.5e-13 47.9 8.2 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain Coiled PF05710.7 KNZ77285.1 - 0.44 11.0 8.5 3.5 8.1 3.7 2.6 2 0 0 2 2 2 0 Coiled coil Sporozoite_P67 PF05642.6 KNZ77285.1 - 0.58 7.9 6.3 0.61 7.8 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HMG_box PF00505.14 KNZ77286.1 - 1.5e-11 44.3 0.7 5.2e-11 42.6 0.5 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KNZ77286.1 - 0.055 13.8 0.2 0.11 12.9 0.1 1.5 1 1 0 1 1 1 0 HMG-box domain DUF4449 PF14613.1 KNZ77287.1 - 2.3e-24 86.1 0.1 2.3e-24 86.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) TilS_C PF11734.3 KNZ77287.1 - 0.13 11.4 0.5 2.5 7.3 0.0 2.7 2 0 0 2 2 2 0 TilS substrate C-terminal domain Rifin_STEVOR PF02009.11 KNZ77289.1 - 0.00021 21.0 0.2 0.00033 20.4 0.1 1.2 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 KNZ77289.1 - 0.00046 19.9 1.0 0.00085 19.0 0.7 1.4 1 0 0 1 1 1 1 TMEM154 protein family Herpes_gE PF02480.11 KNZ77289.1 - 0.0035 15.6 0.2 0.0052 15.1 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E MGC-24 PF05283.6 KNZ77289.1 - 0.013 15.3 9.8 0.023 14.4 6.8 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) TMEM51 PF15345.1 KNZ77289.1 - 0.019 14.6 0.9 0.027 14.1 0.6 1.5 1 1 0 1 1 1 0 Transmembrane protein 51 DUF1180 PF06679.7 KNZ77289.1 - 0.027 14.3 2.2 0.044 13.6 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Mid2 PF04478.7 KNZ77289.1 - 0.028 13.8 2.6 0.05 13.0 1.8 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.1 KNZ77289.1 - 0.033 14.5 0.2 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain gpUL132 PF11359.3 KNZ77289.1 - 0.045 13.0 1.5 0.063 12.5 1.1 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Syndecan PF01034.15 KNZ77289.1 - 0.053 13.1 0.4 0.094 12.3 0.3 1.3 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.10 KNZ77289.1 - 0.098 12.2 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Herpes_capsid PF06112.6 KNZ77289.1 - 5 7.1 12.0 17 5.4 8.3 1.9 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MFS_1 PF07690.11 KNZ77290.1 - 5e-18 64.9 54.8 1.8e-13 49.9 23.6 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily S1FA PF04689.8 KNZ77290.1 - 3.4 7.6 5.2 2.5 8.0 0.0 3.2 3 0 0 3 3 3 0 DNA binding protein S1FA Methyltransf_2 PF00891.13 KNZ77291.1 - 1.4e-32 112.8 0.0 3.4e-32 111.5 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KNZ77291.1 - 2.2e-06 28.2 0.0 6.9e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ77291.1 - 8.3e-06 26.2 0.0 1.8e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ77291.1 - 0.00014 21.4 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ77291.1 - 0.00057 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KNZ77291.1 - 0.0064 16.8 0.0 0.028 14.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ77291.1 - 0.014 15.9 0.0 0.035 14.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 KNZ77291.1 - 0.017 14.2 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 KNZ77291.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase SKN1 PF03935.10 KNZ77292.1 - 5.5e-171 569.1 6.3 1.8e-105 352.9 3.8 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Lyase_1 PF00206.15 KNZ77293.1 - 1.6e-19 70.2 0.1 5.2e-19 68.5 0.0 1.7 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.4 KNZ77293.1 - 1e-16 60.7 0.0 2.5e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus HEM4 PF02602.10 KNZ77294.1 - 1.4e-31 109.5 0.0 1.6e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Mito_carr PF00153.22 KNZ77295.1 - 4.3e-69 228.2 8.0 4.8e-24 83.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3185 PF11381.3 KNZ77295.1 - 0.32 10.8 4.6 4.7 7.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) IncA PF04156.9 KNZ77296.1 - 0.087 12.4 4.1 0.12 11.9 2.9 1.2 1 0 0 1 1 1 0 IncA protein Amidohydro_2 PF04909.9 KNZ77297.1 - 1.8e-27 96.5 0.0 3.1e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase PseudoU_synth_2 PF00849.17 KNZ77297.1 - 7e-19 68.2 0.0 1.1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase GARS_N PF02844.10 KNZ77297.1 - 0.034 14.6 0.0 0.1 13.1 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Rtt106 PF08512.7 KNZ77298.1 - 8.5e-13 48.1 0.0 2e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like SSrecog PF03531.9 KNZ77298.1 - 0.076 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Structure-specific recognition protein (SSRP1) Vfa1 PF08432.5 KNZ77298.1 - 6.9 6.6 9.6 7.4 6.5 0.2 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Glyco_hydro_10 PF00331.15 KNZ77299.1 - 2.8e-94 315.7 0.0 3.2e-94 315.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 SWIB PF02201.13 KNZ77300.1 - 5.4e-16 58.0 0.0 1.4e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 SWIB/MDM2 domain BAR PF03114.13 KNZ77301.1 - 5.4e-34 117.6 8.5 8.3e-34 117.0 5.9 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KNZ77301.1 - 2e-10 39.8 2.0 4.6e-10 38.7 0.2 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KNZ77301.1 - 1.8e-09 37.0 0.0 3.7e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KNZ77301.1 - 5.9e-08 32.0 0.0 1.7e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain DUF883 PF05957.8 KNZ77301.1 - 0.023 15.0 3.6 0.059 13.7 2.5 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Mnd1 PF03962.10 KNZ77301.1 - 0.081 12.5 10.0 0.21 11.2 6.9 1.6 1 0 0 1 1 1 0 Mnd1 family MscS_TM PF12794.2 KNZ77301.1 - 1.1 7.7 4.5 1.7 7.1 3.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 IncA PF04156.9 KNZ77301.1 - 3.8 7.0 6.0 10 5.6 4.1 1.7 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KNZ77301.1 - 5.3 4.7 5.2 7.8 4.2 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ras PF00071.17 KNZ77302.1 - 3.2e-47 159.9 1.3 3.7e-47 159.7 0.9 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ77302.1 - 3.9e-16 59.6 0.1 6.2e-16 58.9 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ77302.1 - 4e-08 32.6 0.0 5e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KNZ77302.1 - 9e-07 28.8 0.1 3.7e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KNZ77302.1 - 9.4e-06 25.1 1.1 0.00024 20.5 0.7 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KNZ77302.1 - 1.5e-05 24.3 0.3 0.00042 19.6 0.2 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KNZ77302.1 - 0.00016 21.5 0.2 0.00047 20.0 0.2 1.8 1 1 0 1 1 1 1 Dynamin family Arch_ATPase PF01637.13 KNZ77302.1 - 0.00017 21.4 0.7 0.00087 19.0 0.5 2.0 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 KNZ77302.1 - 0.00075 19.3 0.1 0.0016 18.3 0.0 1.6 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.15 KNZ77302.1 - 0.011 14.3 1.3 0.1 11.2 0.9 2.5 1 1 0 1 1 1 0 G-protein alpha subunit ATP_bind_1 PF03029.12 KNZ77302.1 - 0.029 13.8 0.5 0.68 9.4 0.1 2.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 KNZ77302.1 - 0.048 12.8 0.1 0.14 11.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 KNZ77302.1 - 0.052 13.2 0.3 0.34 10.6 0.2 2.0 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DNA_pol_B_exo2 PF10108.4 KNZ77302.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB AAA_28 PF13521.1 KNZ77302.1 - 0.078 12.9 0.0 0.31 10.9 0.0 2.0 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 KNZ77302.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain WD40 PF00400.27 KNZ77303.1 - 9.5e-08 31.6 12.8 5.7e-05 22.8 0.1 5.4 5 1 0 5 5 5 2 WD domain, G-beta repeat F-box-like PF12937.2 KNZ77303.1 - 0.054 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.20 KNZ77304.1 - 4.7e-70 235.6 0.0 7.1e-70 235.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77304.1 - 1.7e-37 128.8 0.0 3e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ77304.1 - 1.8e-05 23.8 0.0 3.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KNZ77304.1 - 0.0067 15.7 0.1 0.016 14.5 0.1 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KNZ77304.1 - 0.047 13.4 1.5 0.078 12.6 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family SNase PF00565.12 KNZ77306.1 - 1.4e-08 34.9 0.0 2.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue NB PF04159.8 KNZ77306.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 NB glycoprotein Rifin_STEVOR PF02009.11 KNZ77308.1 - 0.007 16.0 0.1 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family Mid2 PF04478.7 KNZ77308.1 - 0.016 14.6 0.2 0.016 14.6 0.1 3.3 3 1 1 4 4 4 0 Mid2 like cell wall stress sensor Levi_coat PF01819.12 KNZ77308.1 - 0.16 11.5 6.8 0.31 10.6 4.7 1.4 1 0 0 1 1 1 0 Levivirus coat protein Beta-APP PF03494.8 KNZ77308.1 - 6.9 6.2 6.6 2 7.9 1.5 2.1 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) rve PF00665.21 KNZ77309.1 - 9.6e-13 48.2 0.1 9.6e-11 41.8 0.0 2.7 2 1 1 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.1 KNZ77309.1 - 2.2e-05 23.9 0.0 6.3e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 KNZ77309.1 - 0.072 12.6 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain AOX PF01786.12 KNZ77310.1 - 4.2e-11 42.6 0.0 6.3e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Alternative oxidase Tn7_TnsC_Int PF11426.3 KNZ77310.1 - 0.11 12.2 0.0 0.33 10.6 0.0 1.8 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC Sugar_tr PF00083.19 KNZ77310.1 - 0.47 8.9 1.6 0.95 7.9 0.1 2.1 2 1 1 3 3 3 0 Sugar (and other) transporter RNA_pol PF00940.14 KNZ77311.1 - 8.4e-164 544.8 0.0 1.1e-163 544.4 0.0 1.1 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KNZ77311.1 - 1.4e-71 241.3 0.4 1.4e-71 241.3 0.3 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal Histone PF00125.19 KNZ77312.1 - 3.6e-22 78.2 0.0 4.7e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KNZ77312.1 - 0.016 15.2 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-H2C2 PF09337.5 KNZ77313.1 - 6.1e-05 22.3 0.9 0.0001 21.5 0.7 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger DUF1661 PF07877.6 KNZ77314.1 - 0.014 14.9 0.8 0.023 14.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) Prefoldin_2 PF01920.15 KNZ77314.1 - 0.02 14.6 0.2 0.027 14.2 0.2 1.1 1 0 0 1 1 1 0 Prefoldin subunit TFIID_20kDa PF03847.8 KNZ77314.1 - 0.072 13.3 0.0 0.091 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Hydrolase_like2 PF13246.1 KNZ77314.1 - 0.098 12.6 0.0 0.099 12.6 0.0 1.1 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Glyco_hydro_6 PF01341.12 KNZ77315.1 - 5.7e-113 377.2 2.4 7e-113 376.9 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 KNZ77315.1 - 3.9e-12 45.6 2.8 9.9e-12 44.3 2.0 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain ATP_sub_h PF10775.4 KNZ77316.1 - 2.2e-23 81.7 0.8 3.3e-23 81.1 0.6 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 KNZ77316.1 - 0.086 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 IATP PF04568.7 KNZ77317.1 - 2e-09 37.3 1.2 2.2e-09 37.2 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DivIC PF04977.10 KNZ77317.1 - 0.25 10.8 4.2 0.35 10.3 2.9 1.3 1 0 0 1 1 1 0 Septum formation initiator F-box-like PF12937.2 KNZ77318.1 - 0.0003 20.4 0.2 0.00074 19.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like Utp12 PF04003.7 KNZ77318.1 - 0.049 13.5 0.6 9 6.2 0.0 2.9 2 1 0 2 2 2 0 Dip2/Utp12 Family CBM_19 PF03427.8 KNZ77318.1 - 0.11 12.3 0.3 0.21 11.3 0.2 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) DUF1289 PF06945.8 KNZ77319.1 - 0.057 12.9 0.1 0.083 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) p450 PF00067.17 KNZ77320.1 - 5.7e-44 150.3 0.1 6.7e-44 150.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1963 PF09234.5 KNZ77321.1 - 0.0057 16.9 1.6 0.0081 16.4 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) SUR7 PF06687.7 KNZ77322.1 - 1.8e-05 24.3 25.0 0.00087 18.9 17.1 2.8 1 1 1 2 2 2 1 SUR7/PalI family Claudin_2 PF13903.1 KNZ77322.1 - 0.17 11.5 20.6 0.23 11.1 8.6 2.1 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 KNZ77322.1 - 1.8 8.2 8.9 0.28 10.8 3.5 1.7 2 0 0 2 2 2 0 Amastin surface glycoprotein RVP_2 PF08284.6 KNZ77323.1 - 0.032 14.1 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KNZ77323.1 - 0.07 12.9 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Glyco_hydro_16 PF00722.16 KNZ77325.1 - 3.8e-14 52.4 4.2 4.7e-14 52.0 1.6 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Adaptin_N PF01602.15 KNZ77326.1 - 3.2e-153 510.8 5.7 4e-153 510.5 4.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KNZ77326.1 - 5.3e-28 98.0 2.2 2.1e-25 89.6 0.2 3.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KNZ77326.1 - 5.3e-18 65.0 3.8 1.1e-08 35.1 0.0 5.5 1 1 5 6 6 6 5 HEAT repeats HEAT PF02985.17 KNZ77326.1 - 2.5e-08 33.3 9.1 0.00019 21.2 0.1 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 KNZ77326.1 - 4.5e-07 30.1 7.1 0.027 14.9 0.1 6.6 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 KNZ77326.1 - 0.00039 19.8 0.6 0.23 10.7 0.0 3.5 3 1 1 4 4 4 2 CLASP N terminal Arm PF00514.18 KNZ77326.1 - 0.032 14.0 5.0 18 5.3 0.0 5.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Ribonuc_P_40 PF08584.6 KNZ77326.1 - 0.038 12.9 0.0 0.079 11.9 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Bcl-2 PF00452.14 KNZ77326.1 - 0.17 12.0 0.0 0.75 9.9 0.0 2.1 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family SET PF00856.23 KNZ77328.1 - 5.5e-09 36.5 0.1 1.3e-08 35.3 0.0 1.8 1 1 0 1 1 1 1 SET domain TMEM171 PF15471.1 KNZ77330.1 - 0.24 10.1 4.1 0.2 10.3 2.0 1.4 2 0 0 2 2 2 0 Transmembrane protein family 171 RrnaAD PF00398.15 KNZ77331.1 - 5.2e-55 186.3 0.0 6.7e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KNZ77331.1 - 2.6e-08 33.8 0.0 4e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ77331.1 - 2.2e-05 24.9 0.0 4.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ77331.1 - 7.6e-05 22.1 0.0 0.00015 21.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KNZ77331.1 - 0.00011 21.7 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 KNZ77331.1 - 0.00024 20.8 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ77331.1 - 0.0006 20.2 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KNZ77331.1 - 0.0013 18.0 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Ubie_methyltran PF01209.13 KNZ77331.1 - 0.0022 17.1 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KNZ77331.1 - 0.004 16.2 0.0 0.0063 15.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KNZ77331.1 - 0.0058 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ77331.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KNZ77331.1 - 0.028 13.4 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase NodS PF05401.6 KNZ77331.1 - 0.039 13.3 0.1 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 Nodulation protein S (NodS) Met_10 PF02475.11 KNZ77331.1 - 0.074 12.6 0.1 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 Met-10+ like-protein DREV PF05219.7 KNZ77331.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase SUI1 PF01253.17 KNZ77332.1 - 9.9e-13 47.7 0.0 2.8e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.15 KNZ77332.1 - 0.0058 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 PUA domain RepB-RCR_reg PF10723.4 KNZ77332.1 - 0.063 13.0 0.2 0.22 11.2 0.1 1.9 1 0 0 1 1 1 0 Replication regulatory protein RepB SWIB PF02201.13 KNZ77332.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 SWIB/MDM2 domain NUP PF06516.6 KNZ77333.1 - 2e-86 289.6 0.0 2.6e-86 289.3 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) PNP_UDP_1 PF01048.15 KNZ77333.1 - 4.4e-35 120.7 0.0 9.9e-35 119.5 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NUP PF06516.6 KNZ77334.1 - 5.4e-87 291.5 0.1 6.2e-87 291.3 0.1 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) SurE PF01975.12 KNZ77335.1 - 1.1e-34 119.4 1.1 1.7e-34 118.8 0.8 1.3 1 0 0 1 1 1 1 Survival protein SurE CHB_HEX_C_1 PF13290.1 KNZ77335.1 - 0.022 14.5 0.1 0.059 13.1 0.1 1.8 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF4399 PF14347.1 KNZ77336.1 - 0.0014 18.5 0.1 0.0036 17.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4399) LMBR1 PF04791.11 KNZ77336.1 - 0.13 10.8 5.5 0.0086 14.7 0.6 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein Neur_chan_memb PF02932.11 KNZ77336.1 - 0.36 10.6 9.1 0.26 11.1 3.1 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Kelch_4 PF13418.1 KNZ77337.1 - 4.9e-43 144.6 18.6 1e-08 34.8 0.5 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KNZ77337.1 - 4.5e-40 134.9 12.8 1.1e-08 35.0 0.0 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 KNZ77337.1 - 3.7e-37 125.6 5.8 1.1e-07 31.2 0.0 6.1 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KNZ77337.1 - 1.5e-32 110.3 10.7 4.2e-07 29.8 0.1 6.1 3 2 3 6 6 6 6 Kelch motif Kelch_5 PF13854.1 KNZ77337.1 - 2.5e-32 110.2 6.9 2.7e-08 33.5 0.0 5.6 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 KNZ77337.1 - 6.1e-27 92.3 12.0 2.8e-05 23.6 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Cu_bind_like PF02298.12 KNZ77338.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Plastocyanin-like domain DUF1675 PF07897.6 KNZ77339.1 - 0.11 12.2 2.5 0.18 11.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Crust_neurohorm PF01147.12 KNZ77339.1 - 0.12 11.6 0.2 8.5 5.7 0.0 2.5 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family PIF1 PF05970.9 KNZ77340.1 - 2.7e-108 362.1 0.0 3.3e-108 361.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 KNZ77340.1 - 3.4e-07 28.4 0.0 4.5e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ77340.1 - 0.00021 21.4 0.0 0.0005 20.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KNZ77340.1 - 0.0016 18.0 0.3 0.22 11.0 0.1 2.5 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KNZ77340.1 - 0.0039 16.7 0.0 0.0081 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KNZ77340.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Med13_C PF06333.7 KNZ77341.1 - 0.078 11.4 1.3 0.096 11.2 0.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal HECA PF15353.1 KNZ77341.1 - 0.087 12.5 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Headcase protein family homologue V-set PF07686.12 KNZ77341.1 - 0.096 12.5 0.3 0.41 10.5 0.2 2.1 1 1 0 1 1 1 0 Immunoglobulin V-set domain AAA_22 PF13401.1 KNZ77342.1 - 0.0015 18.6 0.0 0.0074 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KNZ77342.1 - 0.025 14.8 0.1 3.2 7.9 0.1 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNZ77342.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain USP7_C2 PF14533.1 KNZ77342.1 - 0.099 12.0 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Got1 PF04178.7 KNZ77343.1 - 3.2e-29 101.4 11.7 4.2e-29 101.0 8.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3414 PF11894.3 KNZ77345.1 - 3e-226 753.8 0.0 4e-226 753.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Chromo PF00385.19 KNZ77346.1 - 3.1e-11 42.7 0.2 7.4e-11 41.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MT-A70 PF05063.9 KNZ77347.1 - 1.8e-38 131.8 0.0 4.4e-38 130.5 0.0 1.6 1 1 0 1 1 1 1 MT-A70 Noc2 PF03715.8 KNZ77348.1 - 9.3e-97 323.4 0.3 1e-95 320.0 0.1 2.2 2 0 0 2 2 2 2 Noc2p family E2_bind PF08825.5 KNZ77349.1 - 0.032 13.9 0.3 0.26 11.0 0.2 1.9 1 1 0 1 1 1 0 E2 binding domain HSP70 PF00012.15 KNZ77350.1 - 0.0018 16.2 0.0 0.0061 14.5 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein BcrAD_BadFG PF01869.15 KNZ77350.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family MreB_Mbl PF06723.8 KNZ77350.1 - 0.039 12.5 0.0 0.087 11.3 0.0 1.5 2 0 0 2 2 2 0 MreB/Mbl protein ALO PF04030.9 KNZ77351.1 - 8.5e-82 274.6 3.5 1.1e-81 274.2 2.4 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KNZ77351.1 - 1.5e-18 66.6 1.2 2.2e-17 62.8 0.8 2.2 1 1 0 1 1 1 1 FAD binding domain UQ_con PF00179.21 KNZ77352.1 - 9.5e-45 151.4 0.0 1.1e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RNA_pol_Rpb2_6 PF00562.23 KNZ77353.1 - 3.2e-121 404.7 0.0 4.9e-121 404.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_2 PF04561.9 KNZ77353.1 - 1.9e-29 102.4 0.0 5.9e-29 100.8 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_1 PF04563.10 KNZ77353.1 - 1.5e-25 89.3 0.0 3.3e-20 71.8 0.1 2.7 2 1 1 3 3 3 2 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KNZ77353.1 - 7.2e-25 87.0 0.1 2.3e-24 85.4 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KNZ77353.1 - 2.8e-23 81.5 1.5 8.8e-23 79.9 1.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KNZ77353.1 - 8.1e-21 73.5 0.0 1.7e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KNZ77353.1 - 2.8e-13 49.5 0.1 6.6e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 UQ_con PF00179.21 KNZ77354.1 - 8.5e-41 138.6 0.0 9.9e-41 138.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KNZ77354.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF2576 PF10845.3 KNZ77354.1 - 0.075 12.2 0.1 0.85 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) SNF2_N PF00176.18 KNZ77355.1 - 5.5e-46 156.7 0.0 9.1e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNZ77355.1 - 1.6e-15 56.7 0.0 8.7e-13 47.9 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain VIGSSK PF14773.1 KNZ77355.1 - 2.1e-07 30.7 0.2 5.2e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal HDA2-3 PF11496.3 KNZ77355.1 - 0.0064 15.3 0.0 0.018 13.8 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SEC-C PF02810.10 KNZ77355.1 - 0.016 14.7 3.3 0.026 14.0 2.3 1.4 1 0 0 1 1 1 0 SEC-C motif DUF4250 PF14056.1 KNZ77355.1 - 0.12 12.0 0.0 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Peptidase_C65 PF10275.4 KNZ77356.1 - 1.6e-54 184.8 0.0 2e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 KNZ77356.1 - 2.6e-06 28.0 0.0 0.041 14.4 0.0 2.4 2 0 0 2 2 2 2 OTU-like cysteine protease DDE_Tnp_IS240 PF13610.1 KNZ77357.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 DDE domain RuBisCO_small PF00101.15 KNZ77357.1 - 0.095 12.5 0.0 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain Oxysterol_BP PF01237.13 KNZ77359.1 - 2.2e-74 250.1 0.0 2.9e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein HMG_box PF00505.14 KNZ77360.1 - 5e-19 68.3 1.6 6.7e-19 67.9 1.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KNZ77360.1 - 8.9e-14 51.6 1.6 1.2e-13 51.2 1.1 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KNZ77360.1 - 0.0014 18.3 0.1 0.0018 18.0 0.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.7 KNZ77360.1 - 0.008 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain GUB_WAK_bind PF13947.1 KNZ77361.1 - 0.0012 19.3 0.0 3.1 8.4 0.0 2.7 2 0 0 2 2 2 2 Wall-associated receptor kinase galacturonan-binding Plug_translocon PF10559.4 KNZ77361.1 - 9.2 5.8 15.5 25 4.4 0.0 5.8 8 0 0 8 8 8 0 Plug domain of Sec61p Aldo_ket_red PF00248.16 KNZ77364.1 - 2.4e-48 164.3 0.0 3e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Nnf1 PF03980.9 KNZ77365.1 - 5.3e-07 29.5 2.3 5.3e-07 29.5 1.6 1.8 1 1 1 2 2 2 1 Nnf1 PEP-utilisers_N PF05524.8 KNZ77365.1 - 0.025 14.3 0.5 0.052 13.3 0.3 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Metal_resist PF13801.1 KNZ77365.1 - 0.081 12.9 0.9 0.19 11.6 0.6 1.6 1 0 0 1 1 1 0 Heavy-metal resistance DUF2797 PF10977.3 KNZ77365.1 - 0.1 12.2 0.3 0.12 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) P4Ha_N PF08336.6 KNZ77365.1 - 0.11 12.2 3.0 0.17 11.7 0.2 2.2 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Prominin PF05478.6 KNZ77365.1 - 0.15 9.6 1.5 0.17 9.4 1.0 1.0 1 0 0 1 1 1 0 Prominin CR6_interact PF10147.4 KNZ77365.1 - 0.16 11.2 3.1 0.24 10.6 2.0 1.4 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DsrD PF08679.6 KNZ77365.1 - 0.26 11.3 1.7 12 5.9 0.0 2.7 3 0 0 3 3 3 0 Dissimilatory sulfite reductase D (DsrD) TSC22 PF01166.13 KNZ77365.1 - 0.38 10.7 4.1 14 5.7 0.1 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF2536 PF10750.4 KNZ77365.1 - 0.45 10.1 5.4 4 7.0 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2536) RNase_E_G PF10150.4 KNZ77365.1 - 0.56 9.3 4.5 0.74 8.9 1.6 1.8 1 1 1 2 2 2 0 Ribonuclease E/G family DivIC PF04977.10 KNZ77365.1 - 0.87 9.1 6.9 0.44 10.0 1.6 2.2 2 0 0 2 2 2 0 Septum formation initiator PQ-loop PF04193.9 KNZ77366.1 - 0.0013 18.1 0.4 0.0051 16.3 0.2 2.0 1 0 0 1 1 1 1 PQ loop repeat NapE PF06796.6 KNZ77366.1 - 0.51 9.6 6.0 22 4.4 4.3 2.5 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Methyltransf_16 PF10294.4 KNZ77367.1 - 4.1e-22 78.4 0.0 7.5e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KNZ77367.1 - 9.5e-05 22.1 0.0 0.00022 20.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ77367.1 - 0.00063 20.3 0.0 0.0012 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KNZ77367.1 - 0.0016 18.0 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 KNZ77367.1 - 0.0034 16.4 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF938 PF06080.7 KNZ77367.1 - 0.0036 16.8 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MTS PF05175.9 KNZ77367.1 - 0.048 13.0 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 KNZ77367.1 - 0.066 13.6 0.1 0.24 11.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Rhomboid PF01694.17 KNZ77368.1 - 3.8e-14 52.9 13.9 3.2e-13 49.9 8.5 2.9 2 1 0 2 2 2 1 Rhomboid family Methyltransf_16 PF10294.4 KNZ77369.1 - 3.8e-26 91.5 0.0 5.7e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase DEAD PF00270.24 KNZ77370.1 - 4e-44 150.0 0.0 9.2e-44 148.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KNZ77370.1 - 1.2e-26 92.0 0.1 2.3e-26 91.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KNZ77370.1 - 1e-20 73.3 0.1 3.8e-20 71.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ77370.1 - 0.0036 17.1 0.0 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit M20_dimer PF07687.9 KNZ77371.1 - 5.9e-10 38.8 0.0 1.3e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Arginosuc_synth PF00764.14 KNZ77372.1 - 1.3e-152 508.4 0.0 1.5e-152 508.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 KNZ77372.1 - 0.00049 19.4 0.0 0.00079 18.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 KNZ77372.1 - 0.01 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.11 KNZ77372.1 - 0.016 13.7 0.0 0.025 13.1 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase zf-RING_2 PF13639.1 KNZ77373.1 - 1.7e-08 34.1 8.6 3e-08 33.3 5.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KNZ77373.1 - 2.6e-08 33.7 7.2 8.8e-08 32.0 5.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNZ77373.1 - 1.9e-07 30.6 6.1 3.2e-07 29.9 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ77373.1 - 2e-06 27.3 5.8 5.4e-06 25.9 4.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ77373.1 - 6.9e-06 25.6 7.1 1.2e-05 24.8 4.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KNZ77373.1 - 0.00014 21.4 1.3 0.00014 21.4 0.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KNZ77373.1 - 0.00015 21.5 5.1 0.00015 21.5 3.5 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KNZ77373.1 - 0.00059 19.5 0.2 0.00059 19.5 0.1 1.6 2 0 0 2 2 1 1 zf-RING of BARD1-type protein YlbD_coat PF14071.1 KNZ77373.1 - 0.00092 19.2 2.0 0.0017 18.4 1.4 1.3 1 0 0 1 1 1 1 Putative coat protein zf-rbx1 PF12678.2 KNZ77373.1 - 0.034 14.2 0.5 0.034 14.2 0.3 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger CemA PF03040.9 KNZ77373.1 - 0.16 11.5 2.1 0.25 10.9 1.5 1.2 1 0 0 1 1 1 0 CemA family Stn1 PF10451.4 KNZ77373.1 - 0.18 10.6 2.0 0.29 9.9 1.4 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 Tup_N PF08581.5 KNZ77373.1 - 0.37 10.9 8.4 0.8 9.9 5.8 1.5 1 0 0 1 1 1 0 Tup N-terminal zf-MIZ PF02891.15 KNZ77373.1 - 1.3 8.6 10.2 0.067 12.7 2.4 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger TMPIT PF07851.8 KNZ77373.1 - 1.7 7.6 5.4 2.6 7.0 3.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Nucleopor_Nup85 PF07575.8 KNZ77374.1 - 1e-53 182.4 0.0 2.4e-53 181.2 0.0 1.5 1 1 0 1 1 1 1 Nup85 Nucleoporin RhoGAP PF00620.22 KNZ77375.1 - 7.8e-47 158.6 0.0 1.9e-46 157.4 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KNZ77375.1 - 1.4e-09 38.0 5.5 3.8e-09 36.6 0.2 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF848 PF05852.6 KNZ77375.1 - 1.2 8.9 8.1 38 4.1 5.0 2.5 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) CorA PF01544.13 KNZ77375.1 - 9.2 5.2 7.9 1.9 7.4 2.9 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TILa PF12714.2 KNZ77377.1 - 1.9 8.2 6.1 1.2 8.9 0.2 2.5 3 0 0 3 3 3 0 TILa domain Histone PF00125.19 KNZ77378.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNZ77378.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KNZ77378.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KNZ77378.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KNZ77378.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KNZ77378.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 KNZ77379.1 - 4.1e-30 103.7 0.8 6.6e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNZ77379.1 - 1.4e-05 25.1 0.1 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KNZ77379.1 - 0.00065 19.7 0.1 0.0013 18.7 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KNZ77379.1 - 0.016 14.9 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KNZ77379.1 - 0.11 11.7 1.5 0.11 11.6 1.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DNA_ligase_A_M PF01068.16 KNZ77381.1 - 1.9e-21 76.4 0.2 5.3e-21 74.9 0.1 1.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KNZ77381.1 - 5.2e-16 58.9 0.0 1.2e-15 57.7 0.0 1.6 2 0 0 2 2 2 1 DNA ligase N terminus RINGv PF12906.2 KNZ77382.1 - 6.6e-16 58.0 8.9 1.1e-15 57.3 6.2 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KNZ77382.1 - 0.084 12.7 8.4 0.15 11.9 5.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 KNZ77382.1 - 0.56 9.8 7.1 0.93 9.1 4.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-AD PF07776.10 KNZ77382.1 - 1.2 9.2 4.5 2 8.4 3.1 1.4 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) zf-RING-like PF08746.6 KNZ77382.1 - 5 7.2 7.8 8.9 6.4 5.4 1.4 1 0 0 1 1 1 0 RING-like domain Herpes_Helicase PF02689.9 KNZ77383.1 - 0.049 11.3 0.0 0.05 11.3 0.0 1.0 1 0 0 1 1 1 0 Helicase TatD_DNase PF01026.16 KNZ77384.1 - 1.1e-40 139.4 0.0 1.3e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 KNZ77384.1 - 9.7e-05 22.0 0.0 0.00054 19.6 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase ARL2_Bind_BART PF11527.3 KNZ77385.1 - 0.0091 15.7 1.2 0.018 14.7 0.8 1.5 1 1 0 1 1 1 1 The ARF-like 2 binding protein BART Z1 PF10593.4 KNZ77385.1 - 0.014 14.5 2.8 0.025 13.7 1.9 1.3 1 0 0 1 1 1 0 Z1 domain APG6 PF04111.7 KNZ77385.1 - 0.43 9.5 5.0 0.61 9.0 3.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3450 PF11932.3 KNZ77385.1 - 1 8.5 8.6 1 8.6 4.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin PF00804.20 KNZ77385.1 - 1.3 9.2 7.3 3.8 7.7 5.0 1.9 1 1 0 1 1 1 0 Syntaxin DUF16 PF01519.11 KNZ77385.1 - 2.1 8.6 5.6 2 8.6 3.0 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 Chromo PF00385.19 KNZ77387.1 - 2.5e-11 43.0 0.2 7.4e-11 41.5 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KNZ77387.1 - 0.0001 22.0 0.0 0.032 14.0 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Mcm10 PF09332.6 KNZ77387.1 - 2.1 7.6 10.1 0.079 12.2 1.4 2.0 2 0 0 2 2 2 0 Mcm10 replication factor RRM_1 PF00076.17 KNZ77388.1 - 1.7e-15 56.3 0.1 2.7e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ77388.1 - 2.3e-12 46.7 0.1 8.5e-12 44.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ77388.1 - 9.8e-06 25.3 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) XRCC4 PF06632.7 KNZ77388.1 - 0.068 12.0 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 RRM_3 PF08777.6 KNZ77388.1 - 0.076 12.8 0.1 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif zf-MYND PF01753.13 KNZ77389.1 - 4.5e-07 29.6 17.4 1e-06 28.5 12.1 1.6 1 0 0 1 1 1 1 MYND finger DUF3846 PF12957.2 KNZ77389.1 - 0.051 13.3 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) zf-Mss51 PF13824.1 KNZ77389.1 - 0.074 12.9 9.2 0.16 11.8 6.4 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3762 PF12591.3 KNZ77389.1 - 0.65 10.0 3.2 0.35 10.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3762) ECR1_N PF14382.1 KNZ77390.1 - 1.5e-14 52.9 0.2 2.6e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KNZ77390.1 - 0.0013 18.6 0.0 0.057 13.3 0.0 2.6 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Pox_Ag35 PF03286.9 KNZ77391.1 - 0.001 18.6 1.0 0.0011 18.5 0.7 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein BNIP3 PF06553.7 KNZ77391.1 - 5.4 6.3 6.9 7.5 5.8 4.8 1.2 1 0 0 1 1 1 0 BNIP3 Daxx PF03344.10 KNZ77391.1 - 5.6 5.3 16.5 6.9 5.0 11.4 1.0 1 0 0 1 1 1 0 Daxx Family TFIIIC_delta PF12657.2 KNZ77392.1 - 1.4e-19 70.4 0.4 3.7e-19 69.0 0.3 1.7 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 KNZ77392.1 - 1.6e-16 60.0 0.9 3.2e-16 59.0 0.6 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex PQQ_3 PF13570.1 KNZ77392.1 - 0.13 12.5 0.5 0.95 9.8 0.2 2.5 2 0 0 2 2 2 0 PQQ-like domain DNA_ligase_ZBD PF03119.11 KNZ77392.1 - 1 9.1 5.9 0.34 10.6 0.9 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Pro-kuma_activ PF09286.6 KNZ77393.1 - 3.4e-36 124.4 0.1 2.8e-35 121.4 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KNZ77393.1 - 3.1e-08 33.0 1.4 3.1e-08 33.0 1.0 1.7 2 0 0 2 2 2 1 Subtilase family FAT PF02259.18 KNZ77394.1 - 3.2e-116 388.1 1.1 3.2e-116 388.1 0.8 2.3 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 KNZ77394.1 - 3.6e-57 193.5 0.2 8.2e-57 192.3 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 KNZ77394.1 - 9.6e-46 155.6 0.3 4.9e-44 150.0 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 KNZ77394.1 - 5.6e-37 125.8 1.1 2.4e-36 123.8 0.1 2.7 2 0 0 2 2 2 1 Rapamycin binding domain FATC PF02260.15 KNZ77394.1 - 1.1e-15 56.7 0.3 2.4e-15 55.6 0.2 1.6 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 KNZ77394.1 - 5.6e-15 55.3 11.9 0.013 15.7 0.0 8.8 5 2 2 7 7 7 3 HEAT repeats TPR_19 PF14559.1 KNZ77394.1 - 1.1e-05 25.6 0.2 0.033 14.5 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat HEAT PF02985.17 KNZ77394.1 - 2.9e-05 23.7 16.6 0.49 10.6 0.0 9.3 10 0 0 10 10 9 2 HEAT repeat HEAT_EZ PF13513.1 KNZ77394.1 - 0.0001 22.6 20.6 0.087 13.3 0.0 9.5 10 1 2 12 12 8 2 HEAT-like repeat CLASP_N PF12348.3 KNZ77394.1 - 0.001 18.4 1.6 9.5 5.4 0.0 5.4 6 0 0 6 6 6 0 CLASP N terminal Cnd1 PF12717.2 KNZ77394.1 - 0.0015 18.4 0.8 7.8 6.3 0.0 4.5 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 TPR_9 PF13371.1 KNZ77394.1 - 0.0032 17.2 2.3 0.56 10.0 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ77394.1 - 0.011 16.3 1.6 0.55 11.0 0.0 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ77394.1 - 0.012 15.3 3.0 0.085 12.6 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ77394.1 - 0.02 14.5 1.3 0.19 11.3 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 KNZ77394.1 - 0.035 13.9 0.3 2.9 8.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat H_kinase_N PF12282.3 KNZ77396.1 - 0.096 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Signal transduction histidine kinase TPR_12 PF13424.1 KNZ77399.1 - 5.4e-27 93.5 36.1 5.6e-05 22.9 1.4 10.7 8 4 2 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ77399.1 - 2.7e-11 42.4 25.6 0.31 11.0 1.1 11.7 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ77399.1 - 1e-07 32.4 3.7 5.9 7.6 0.0 6.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ77399.1 - 1.8e-06 27.4 16.4 1 9.0 0.2 7.5 7 0 0 7 7 7 3 TPR repeat TPR_1 PF00515.23 KNZ77399.1 - 5.7e-06 25.7 16.9 2.2 8.0 0.7 9.3 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_3 PF07720.7 KNZ77399.1 - 0.0054 16.5 0.4 2.1 8.2 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ77399.1 - 0.024 14.9 10.5 0.098 13.0 0.1 5.4 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ77399.1 - 0.03 14.2 37.8 5.5 7.0 0.0 12.6 16 1 0 16 16 15 0 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ77399.1 - 0.13 12.9 28.6 2.5 8.9 0.0 10.2 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ77399.1 - 1 9.7 8.4 47 4.5 0.2 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ77399.1 - 1.1 9.2 12.3 6.9 6.6 0.8 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Asp PF00026.18 KNZ77400.1 - 5.9e-69 232.7 0.4 7.1e-69 232.4 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNZ77400.1 - 3e-07 30.5 1.3 2.5e-06 27.5 0.5 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KNZ77400.1 - 0.016 15.7 0.3 0.24 11.9 0.1 2.9 2 1 0 2 2 2 0 Aspartyl protease Histone PF00125.19 KNZ77401.1 - 1.3e-30 105.3 0.8 2.2e-30 104.5 0.2 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNZ77401.1 - 5.2e-05 23.3 0.1 0.00024 21.2 0.0 1.8 2 0 0 2 2 2 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KNZ77401.1 - 0.01 15.8 0.2 0.026 14.5 0.0 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KNZ77401.1 - 0.026 13.7 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1065 PF06358.6 KNZ77401.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1065) Histone PF00125.19 KNZ77402.1 - 4.1e-30 103.7 0.8 6.6e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNZ77402.1 - 1.4e-05 25.1 0.1 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KNZ77402.1 - 0.00065 19.7 0.1 0.0013 18.7 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KNZ77402.1 - 0.016 14.9 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KNZ77402.1 - 0.11 11.7 1.5 0.11 11.6 1.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 KNZ77403.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNZ77403.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KNZ77403.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KNZ77403.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KNZ77403.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KNZ77403.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit SIR2 PF02146.12 KNZ77405.1 - 1.5e-37 129.0 0.0 2.8e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KNZ77405.1 - 1.1e-06 28.3 0.0 2.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) zf-PHD-like PF15446.1 KNZ77405.1 - 0.0013 18.0 0.3 0.0023 17.2 0.2 1.3 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Phospholip_A2_3 PF09056.6 KNZ77406.1 - 0.053 13.7 1.7 0.11 12.7 0.7 1.9 1 1 1 2 2 2 0 Prokaryotic phospholipase A2 Tenui_NS4 PF03300.8 KNZ77406.1 - 1.1 8.2 4.8 1.3 7.9 3.3 1.1 1 0 0 1 1 1 0 Tenuivirus non-structural protein NS4 AAA_13 PF13166.1 KNZ77406.1 - 2.8 6.2 19.4 3.3 6.0 13.5 1.1 1 0 0 1 1 1 0 AAA domain Ly49 PF08391.5 KNZ77406.1 - 5.4 7.1 8.5 0.43 10.7 0.5 2.0 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF4641 PF15483.1 KNZ77407.1 - 0.035 12.8 1.5 0.048 12.3 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4641) YhjQ PF06564.7 KNZ77407.1 - 0.045 13.0 0.1 0.07 12.4 0.1 1.2 1 0 0 1 1 1 0 YhjQ protein Aldo_ket_red PF00248.16 KNZ77408.1 - 5.2e-50 169.8 0.0 6.3e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.2 KNZ77409.1 - 0.00056 19.5 0.6 0.0015 18.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like Prok-RING_1 PF14446.1 KNZ77409.1 - 0.16 11.6 2.2 5.1 6.8 0.1 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DLH PF01738.13 KNZ77410.1 - 3.9e-14 52.4 0.0 4.7e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KNZ77410.1 - 0.028 14.1 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PTS_2-RNA PF01885.11 KNZ77412.1 - 1.3e-61 207.1 0.0 1.7e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family NinB PF05772.7 KNZ77412.1 - 0.04 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 NinB protein RTC4 PF14474.1 KNZ77413.1 - 7.7e-25 87.2 0.0 2e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 RTC4-like domain Acetyltransf_10 PF13673.1 KNZ77415.1 - 0.00024 21.2 0.0 0.00046 20.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KNZ77415.1 - 0.00024 21.1 0.0 0.00048 20.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ77415.1 - 0.0029 17.5 0.0 0.0075 16.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KNZ77416.1 - 3.4e-15 56.4 0.0 5.6e-15 55.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ77416.1 - 1.1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KNZ77416.1 - 0.0029 17.5 0.0 0.0041 17.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain CBM_5_12 PF02839.9 KNZ77417.1 - 5.9e-12 44.9 16.1 5.9e-12 44.9 11.2 3.1 3 0 0 3 3 3 2 Carbohydrate binding domain DUF2015 PF09435.5 KNZ77418.1 - 6.2e-34 116.5 0.3 7e-34 116.3 0.2 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Smr PF01713.16 KNZ77419.1 - 1.6e-10 41.0 0.5 6.6e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.5 KNZ77419.1 - 6.1e-06 26.1 2.5 1.2e-05 25.2 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) DIM1 PF02966.11 KNZ77420.1 - 4.7e-68 226.8 0.0 5.2e-68 226.6 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 KNZ77420.1 - 4.2e-05 23.1 0.1 5.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredox_DsbH PF03190.10 KNZ77420.1 - 0.056 13.1 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_8 PF13905.1 KNZ77420.1 - 0.091 12.8 0.2 0.13 12.4 0.2 1.3 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.1 KNZ77420.1 - 0.11 12.5 0.1 0.23 11.5 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin-like CorA PF01544.13 KNZ77421.1 - 0.014 14.3 3.3 0.023 13.7 2.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HSCB_C PF07743.8 KNZ77421.1 - 4.4 7.8 8.1 0.99 9.9 1.2 2.9 1 1 2 3 3 3 0 HSCB C-terminal oligomerisation domain VPS9 PF02204.13 KNZ77422.1 - 2e-17 63.0 0.0 2.5e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain IlvN PF07991.7 KNZ77425.1 - 2.1e-46 157.3 0.2 3.4e-46 156.6 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain RRM_1 PF00076.17 KNZ77425.1 - 1.2e-40 136.9 0.2 4.6e-20 71.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ77425.1 - 1.1e-30 105.3 0.1 1.9e-14 53.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ77425.1 - 5.3e-23 80.6 0.0 2e-09 37.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KNZ77425.1 - 5.6e-20 71.3 0.5 1.3e-19 70.1 0.4 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein F420_oxidored PF03807.12 KNZ77425.1 - 2e-08 34.5 0.2 4.5e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KNZ77425.1 - 3.8e-05 23.5 0.1 0.00012 21.9 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase RRM_3 PF08777.6 KNZ77425.1 - 0.00011 22.0 0.6 0.023 14.5 0.0 2.7 2 0 0 2 2 2 1 RNA binding motif NAD_Gly3P_dh_N PF01210.18 KNZ77425.1 - 0.022 14.4 0.3 0.09 12.4 0.2 1.9 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short PF00106.20 KNZ77426.1 - 9.6e-27 93.9 0.0 2.8e-26 92.4 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ77426.1 - 4.7e-22 78.9 0.1 1.1e-21 77.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ77426.1 - 1.3e-12 47.7 0.1 2.2e-11 43.7 0.1 2.0 1 1 0 1 1 1 1 KR domain Birna_VP5 PF03042.9 KNZ77426.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Birnavirus VP5 protein Cupin_2 PF07883.6 KNZ77427.1 - 1.2e-05 24.6 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KNZ77427.1 - 0.013 14.9 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Cupin Imm45 PF15603.1 KNZ77427.1 - 0.014 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 45 Auxin_BP PF02041.11 KNZ77427.1 - 0.095 12.1 0.1 0.17 11.3 0.0 1.4 2 0 0 2 2 2 0 Auxin binding protein Pex16 PF08610.5 KNZ77428.1 - 3.1e-77 259.8 1.3 3.7e-77 259.5 0.9 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF1489 PF07370.6 KNZ77429.1 - 0.0082 15.6 0.0 0.025 14.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1489) WES_acyltransf PF03007.11 KNZ77429.1 - 0.032 13.7 0.3 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Stm1_N PF09598.5 KNZ77429.1 - 9.4 7.0 7.6 0.9 10.2 0.9 2.3 2 0 0 2 2 2 0 Stm1 CorA PF01544.13 KNZ77430.1 - 4.2e-21 75.2 0.2 2.4e-14 53.0 0.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF947 PF06102.7 KNZ77431.1 - 1.3e-34 119.4 17.0 1.3e-34 119.4 11.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF947) IMP_cyclohyd PF07826.6 KNZ77431.1 - 0.0023 17.3 0.1 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 IMP cyclohydrolase-like protein D-ser_dehydrat PF14031.1 KNZ77432.1 - 6.8e-19 67.8 0.0 3.9e-18 65.4 0.0 2.2 3 0 0 3 3 3 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KNZ77432.1 - 2.7e-05 23.8 0.0 3.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DSRB PF10781.4 KNZ77432.1 - 0.024 14.0 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Dextransucrase DSRB BMC PF00936.14 KNZ77432.1 - 0.097 12.3 0.1 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 BMC domain Ras PF00071.17 KNZ77433.1 - 1.8e-46 157.4 0.0 2.2e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ77433.1 - 2.3e-17 63.6 0.0 2.8e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ77433.1 - 1.6e-12 47.0 0.0 2e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KNZ77433.1 - 1.9e-05 24.6 0.0 2.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KNZ77433.1 - 2.9e-05 23.5 0.0 0.00042 19.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KNZ77433.1 - 0.0002 20.6 0.0 0.00022 20.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region KaiC PF06745.8 KNZ77433.1 - 0.0014 17.8 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 KNZ77433.1 - 0.0023 18.0 0.0 0.0035 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 KNZ77433.1 - 0.0025 17.0 0.0 0.0034 16.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KNZ77433.1 - 0.023 14.6 0.1 0.028 14.3 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 KNZ77433.1 - 0.028 14.1 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.4 KNZ77433.1 - 0.034 13.0 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.22 KNZ77433.1 - 0.037 14.3 0.0 0.042 14.1 0.0 1.3 1 1 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.12 KNZ77433.1 - 0.042 13.3 0.0 1.9 7.9 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Methyltransf_25 PF13649.1 KNZ77433.1 - 0.072 13.4 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2075 PF09848.4 KNZ77433.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_15 PF13175.1 KNZ77433.1 - 0.1 11.5 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.21 KNZ77433.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Septin PF00735.13 KNZ77433.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Septin DUF2029 PF09594.5 KNZ77434.1 - 0.0024 17.4 1.0 0.0039 16.7 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2029) Isochorismatase PF00857.15 KNZ77435.1 - 9e-24 84.3 0.0 1.8e-23 83.3 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family Herpes_gE PF02480.11 KNZ77436.1 - 0.017 13.4 0.0 0.024 12.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM51 PF15345.1 KNZ77436.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Transmembrane protein 51 DUF1180 PF06679.7 KNZ77436.1 - 0.2 11.5 1.1 0.79 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) G_glu_transpept PF01019.16 KNZ77438.1 - 4.8e-136 454.2 0.0 1e-135 453.1 0.0 1.5 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase Galactosyl_T PF01762.16 KNZ77440.1 - 7.3e-09 35.5 0.0 0.00096 18.7 0.0 2.5 2 1 0 2 2 2 2 Galactosyltransferase Glyco_trans_2_3 PF13632.1 KNZ77440.1 - 0.26 10.9 4.4 0.45 10.2 0.7 2.6 2 1 0 2 2 2 0 Glycosyl transferase family group 2 UPF0104 PF03706.8 KNZ77440.1 - 5.5 6.1 6.0 9.1 5.4 4.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) GST_N_3 PF13417.1 KNZ77441.1 - 4.3e-11 42.8 0.0 9e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KNZ77441.1 - 4.5e-08 32.9 0.0 1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KNZ77441.1 - 0.00083 19.1 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KNZ77441.1 - 0.0015 18.6 0.0 0.0077 16.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KNZ77441.1 - 0.0021 17.9 0.1 0.023 14.6 0.0 2.7 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain SGS PF05002.10 KNZ77442.1 - 2.3e-30 104.1 5.2 3.3e-30 103.6 3.6 1.2 1 0 0 1 1 1 1 SGS domain CS PF04969.11 KNZ77442.1 - 3.3e-08 33.9 0.0 5.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 CS domain DHFR_1 PF00186.14 KNZ77443.1 - 7.7e-31 106.8 0.0 1.5e-30 105.9 0.0 1.6 1 1 0 1 1 1 1 Dihydrofolate reductase Ribosomal_L36 PF00444.13 KNZ77444.1 - 3.1e-17 62.2 11.1 4.6e-17 61.7 7.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Arc_trans_TRASH PF08394.5 KNZ77444.1 - 0.3 11.2 1.7 0.58 10.3 1.1 1.4 1 0 0 1 1 1 0 Archaeal TRASH domain EmrE PF13536.1 KNZ77445.1 - 1.6e-10 41.1 10.2 1.6e-10 41.1 7.1 3.2 3 1 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 KNZ77445.1 - 4.9e-05 23.3 10.1 4.9e-05 23.3 7.0 3.4 2 1 2 4 4 4 2 EamA-like transporter family Metallophos PF00149.23 KNZ77446.1 - 2.8e-34 118.2 0.1 3.4e-34 118.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MPC PF03650.8 KNZ77447.1 - 1e-19 70.6 0.2 1.6e-19 70.0 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Ribosomal_S17 PF00366.15 KNZ77447.1 - 2.5e-16 59.4 0.0 3.6e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 DNA_ligase_A_M PF01068.16 KNZ77448.1 - 9.9e-63 211.1 0.2 1.5e-62 210.5 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KNZ77448.1 - 2e-51 174.2 0.6 3.7e-51 173.4 0.4 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KNZ77448.1 - 3.8e-26 91.3 0.3 1.3e-25 89.6 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 KNZ77448.1 - 0.0077 15.8 0.1 1 9.0 0.0 2.6 2 0 0 2 2 2 1 DNA ligase OB-like domain NUDIX PF00293.23 KNZ77450.1 - 5.6e-25 87.5 0.0 7.5e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NSP10 PF09401.5 KNZ77454.1 - 0.019 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 RNA synthesis protein NSP10 Kelch_4 PF13418.1 KNZ77456.1 - 1e-27 95.6 13.6 1.1e-05 25.0 0.2 6.6 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KNZ77456.1 - 3.5e-24 84.3 16.5 1.7e-07 31.1 0.0 7.2 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.20 KNZ77456.1 - 2.1e-22 78.3 0.4 3.9e-06 26.2 0.0 5.2 5 0 0 5 5 5 4 Kelch motif DUF4110 PF13422.1 KNZ77456.1 - 2.3e-22 78.6 0.0 2.3e-22 78.6 0.0 3.4 3 2 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 KNZ77456.1 - 3.1e-21 74.5 5.0 8.7e-05 22.5 0.1 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 KNZ77456.1 - 2.9e-18 65.4 9.9 0.004 17.0 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 KNZ77456.1 - 1.8e-10 40.1 15.1 6.4e-06 25.7 0.1 6.0 6 1 0 6 6 6 3 Kelch motif Spore_coat_CotO PF14153.1 KNZ77456.1 - 0.0025 17.3 3.2 0.32 10.4 0.0 2.4 2 0 0 2 2 2 2 Spore coat protein CotO Cwf_Cwc_15 PF04889.7 KNZ77456.1 - 0.012 15.3 0.9 0.012 15.3 0.6 3.2 4 0 0 4 4 4 0 Cwf15/Cwc15 cell cycle control protein RNase_H PF00075.19 KNZ77457.1 - 5.7e-13 49.3 0.0 1.3e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 KNZ77457.1 - 2.9e-08 33.3 0.1 5.4e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.1 KNZ77457.1 - 1e-05 25.7 0.1 2.5e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.18 KNZ77457.1 - 0.0031 17.4 0.2 0.0075 16.2 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Tox-GHH PF15636.1 KNZ77458.1 - 0.096 12.3 1.6 0.15 11.6 0.3 1.9 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF883 PF05957.8 KNZ77458.1 - 2.2 8.7 9.2 0.09 13.1 0.5 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 KNZ77458.1 - 2.9 8.3 7.0 0.5 10.7 1.4 2.3 2 0 0 2 2 2 0 YtxH-like protein DUF1211 PF06736.6 KNZ77459.1 - 0.03 14.4 1.3 0.046 13.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) ELFV_dehydrog PF00208.16 KNZ77461.1 - 2.4e-71 240.1 0.2 2.9e-71 239.9 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KNZ77461.1 - 1.9e-46 156.8 0.0 3.6e-46 155.9 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain zf-RVT PF13966.1 KNZ77463.1 - 0.00058 20.1 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.2 KNZ77463.1 - 0.0078 15.9 2.6 0.0078 15.9 1.8 2.0 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 KNZ77463.1 - 0.035 14.0 2.6 1.5 8.7 0.0 2.6 2 1 0 2 2 2 0 Zinc ribbon domain Exo70 PF03081.10 KNZ77465.1 - 1.9e-30 105.8 4.1 3.9e-30 104.8 0.5 2.0 2 0 0 2 2 2 1 Exo70 exocyst complex subunit GCR PF02155.10 KNZ77465.1 - 0.04 12.6 0.4 0.068 11.8 0.2 1.4 1 0 0 1 1 1 0 Glucocorticoid receptor DUF2120 PF09893.4 KNZ77465.1 - 0.21 11.5 1.7 11 6.0 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF883 PF05957.8 KNZ77465.1 - 4.5 7.7 5.4 3.7 7.9 0.9 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Peptidase_M36 PF02128.10 KNZ77466.1 - 2.2e-112 375.6 6.2 2.6e-112 375.3 4.3 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.10 KNZ77466.1 - 0.0068 16.1 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_MA_2 PF13485.1 KNZ77466.1 - 0.053 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Peptidase_M4 PF01447.13 KNZ77466.1 - 0.22 11.6 8.9 3 7.9 6.2 2.4 1 1 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain CBFD_NFYB_HMF PF00808.18 KNZ77467.1 - 7.4e-27 93.1 0.4 1.2e-26 92.5 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KNZ77467.1 - 9.8e-06 25.6 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KNZ77467.1 - 0.003 17.3 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit GMC_oxred_N PF00732.14 KNZ77468.1 - 2.5e-69 233.7 0.0 3.1e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ77468.1 - 1.3e-36 126.0 0.1 1e-35 123.1 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KNZ77468.1 - 9e-06 24.7 0.2 0.017 13.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KNZ77468.1 - 0.00037 19.5 0.1 0.00066 18.6 0.0 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KNZ77468.1 - 0.0014 18.6 0.0 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KNZ77468.1 - 0.0046 15.9 0.1 0.019 13.8 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KNZ77468.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 KNZ77468.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Pkinase PF00069.20 KNZ77470.1 - 9.1e-17 61.0 0.0 2.4e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77470.1 - 0.002 17.2 0.0 3.3 6.7 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.20 KNZ77472.1 - 3.1e-15 56.0 0.0 3.6e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77472.1 - 7.2e-05 21.9 0.0 8.9e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Lactamase_B PF00753.22 KNZ77472.1 - 0.003 17.2 0.1 0.0037 16.9 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Kdo PF06293.9 KNZ77472.1 - 0.018 14.1 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zn_Tnp_IS1595 PF12760.2 KNZ77473.1 - 0.0074 16.0 0.2 0.02 14.6 0.2 1.8 1 0 0 1 1 1 1 Transposase zinc-ribbon domain GHMP_kinases_C PF08544.8 KNZ77475.1 - 0.11 12.6 0.6 0.15 12.2 0.4 1.3 1 0 0 1 1 1 0 GHMP kinases C terminal PIF1 PF05970.9 KNZ77479.1 - 8.8e-110 367.0 0.0 1.1e-109 366.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 KNZ77479.1 - 3.4e-07 28.4 0.0 4.5e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ77479.1 - 0.00021 21.3 0.0 0.0005 20.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 KNZ77479.1 - 0.00025 20.6 0.0 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KNZ77479.1 - 0.0011 18.4 0.4 0.15 11.5 0.1 2.5 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KNZ77479.1 - 0.082 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.10 KNZ77479.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helitron_like_N PF14214.1 KNZ77480.1 - 2.5e-62 209.8 0.1 3.2e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ77480.1 - 0.018 14.6 0.0 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) Phage_GPA PF05840.8 KNZ77480.1 - 0.036 12.7 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Myosin_tail_1 PF01576.14 KNZ77481.1 - 0.0013 16.5 19.8 0.0015 16.3 13.7 1.1 1 0 0 1 1 1 1 Myosin tail DUF869 PF05911.6 KNZ77481.1 - 0.0076 14.5 16.7 0.024 12.8 8.3 2.0 1 1 1 2 2 2 2 Plant protein of unknown function (DUF869) DUF2968 PF11180.3 KNZ77481.1 - 0.0077 15.6 1.4 0.0077 15.6 0.9 2.1 1 1 2 3 3 3 1 Protein of unknown function (DUF2968) Reo_sigmaC PF04582.7 KNZ77481.1 - 0.0083 15.3 0.3 0.016 14.4 0.2 1.4 1 1 0 1 1 1 1 Reovirus sigma C capsid protein Nup54 PF13874.1 KNZ77481.1 - 0.0084 15.7 8.2 0.012 15.2 5.7 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 MscS_porin PF12795.2 KNZ77481.1 - 0.0091 15.3 7.6 0.011 15.1 5.3 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF1202 PF06717.6 KNZ77481.1 - 0.012 14.9 3.6 0.012 14.9 2.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1202) DUF1664 PF07889.7 KNZ77481.1 - 0.019 14.7 9.2 0.15 11.8 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GOLGA2L5 PF15070.1 KNZ77481.1 - 0.019 13.5 17.1 0.021 13.3 11.8 1.0 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 ATG16 PF08614.6 KNZ77481.1 - 0.032 14.0 16.2 0.083 12.7 11.2 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4200 PF13863.1 KNZ77481.1 - 0.056 13.3 19.7 0.043 13.7 11.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMCO5 PF14992.1 KNZ77481.1 - 0.081 12.0 19.4 0.092 11.8 13.4 1.1 1 0 0 1 1 1 0 TMCO5 family DUF342 PF03961.8 KNZ77481.1 - 0.11 10.9 7.2 0.12 10.7 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TSC22 PF01166.13 KNZ77481.1 - 0.12 12.3 13.6 4 7.4 0.3 3.8 2 1 2 4 4 4 0 TSC-22/dip/bun family Bacillus_HBL PF05791.6 KNZ77481.1 - 0.13 11.5 8.2 0.37 10.1 3.6 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) PspA_IM30 PF04012.7 KNZ77481.1 - 0.15 11.4 10.8 1.1 8.5 2.8 2.4 1 1 1 2 2 2 0 PspA/IM30 family Tropomyosin_1 PF12718.2 KNZ77481.1 - 0.18 11.6 21.8 0.55 10.0 8.4 2.3 1 1 0 1 1 1 0 Tropomyosin like DUF972 PF06156.8 KNZ77481.1 - 0.25 11.7 16.2 4 7.8 3.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CCDC155 PF14662.1 KNZ77481.1 - 0.26 10.8 19.6 0.04 13.5 10.1 1.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 FadA PF09403.5 KNZ77481.1 - 0.31 11.0 14.8 0.43 10.5 5.9 2.2 1 1 1 2 2 2 0 Adhesion protein FadA APG6 PF04111.7 KNZ77481.1 - 0.33 9.9 20.4 0.65 8.9 14.2 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 KNZ77481.1 - 0.56 10.0 19.5 2 8.2 12.5 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.6 KNZ77481.1 - 0.59 8.3 15.7 0.72 8.0 10.9 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADIP PF11559.3 KNZ77481.1 - 0.67 9.8 22.5 0.97 9.3 11.3 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding AATF-Che1 PF13339.1 KNZ77481.1 - 0.71 10.0 13.5 0.18 11.9 5.8 2.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor V_ATPase_I PF01496.14 KNZ77481.1 - 0.79 7.5 11.6 0.85 7.3 7.6 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 KNZ77481.1 - 1.1 8.8 14.5 4.6 6.7 9.7 2.2 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) I_LWEQ PF01608.12 KNZ77481.1 - 1.2 9.0 9.2 0.84 9.5 5.2 1.6 1 1 0 1 1 1 0 I/LWEQ domain DUF641 PF04859.7 KNZ77481.1 - 1.3 8.8 14.4 0.087 12.5 2.0 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) GAS PF13851.1 KNZ77481.1 - 1.8 7.7 22.5 4.1 6.5 3.2 2.8 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 KNZ77481.1 - 1.8 8.3 14.4 10 5.9 8.8 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 KNZ77481.1 - 1.9 8.0 10.5 7.8 6.0 0.4 2.7 1 1 0 2 2 2 0 Septum formation initiator Microtub_bind PF13931.1 KNZ77481.1 - 1.9 8.5 13.0 0.64 10.1 4.5 2.1 1 1 0 2 2 2 0 Kinesin-associated microtubule-binding DUF4446 PF14584.1 KNZ77481.1 - 2.1 8.1 8.9 1.4 8.7 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) HALZ PF02183.13 KNZ77481.1 - 3 7.6 11.7 24 4.7 2.3 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper Lzipper-MIP1 PF14389.1 KNZ77481.1 - 3.3 7.9 10.7 1.1 9.3 3.2 2.7 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF4140 PF13600.1 KNZ77481.1 - 3.9 7.9 8.1 14 6.1 0.2 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Transposase_22 PF02994.9 KNZ77481.1 - 5.3 5.4 13.8 3.9 5.8 7.6 2.2 1 1 1 2 2 2 0 L1 transposable element CENP-Q PF13094.1 KNZ77481.1 - 5.8 6.9 19.1 6.7 6.7 6.1 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Seryl_tRNA_N PF02403.17 KNZ77481.1 - 6.5 6.8 13.8 30 4.6 9.6 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.6 KNZ77481.1 - 7.4 7.0 10.9 6 7.3 3.6 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal gag-asp_proteas PF13975.1 KNZ77482.1 - 0.14 12.0 0.1 0.39 10.5 0.1 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ77483.1 - 8.2e-07 29.4 0.0 1.9e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ77483.1 - 0.00085 18.8 0.4 0.018 14.6 0.1 2.6 1 1 2 3 3 3 1 Aspartyl protease NSP10 PF09401.5 KNZ77483.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA synthesis protein NSP10 Asp_protease_2 PF13650.1 KNZ77486.1 - 0.0028 18.1 0.0 0.0041 17.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KNZ77486.1 - 0.0047 16.7 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KNZ77486.1 - 0.0072 16.2 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease CPSase_L_D2 PF02786.12 KNZ77488.1 - 2.1e-07 30.4 0.1 2.2e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 KNZ77488.1 - 0.035 13.5 0.0 0.035 13.5 0.0 1.0 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Sp100 PF03172.8 KNZ77490.1 - 0.052 13.5 1.0 0.15 12.0 0.1 2.1 1 1 1 2 2 2 0 Sp100 domain Spc42p PF11544.3 KNZ77490.1 - 0.25 11.2 14.8 1.4 8.8 1.4 3.5 1 1 1 3 3 3 0 Spindle pole body component Spc42p Propep_M14 PF02244.11 KNZ77490.1 - 0.92 9.2 7.5 0.82 9.3 0.1 3.6 3 1 0 4 4 4 0 Carboxypeptidase activation peptide Spc7 PF08317.6 KNZ77490.1 - 2.7 6.5 29.5 0.063 11.9 10.7 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6 PF04111.7 KNZ77490.1 - 5 6.0 24.0 6.3 5.7 15.9 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 zf-C4H2 PF10146.4 KNZ77490.1 - 5.3 6.9 15.7 6.7 6.6 10.7 1.2 1 1 0 1 1 1 0 Zinc finger-containing protein rve PF00665.21 KNZ77492.1 - 0.0046 17.0 0.0 0.0053 16.8 0.0 1.3 1 1 0 1 1 1 1 Integrase core domain Chromo PF00385.19 KNZ77493.1 - 0.0084 15.7 1.1 0.015 14.9 0.7 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Lipase_GDSL PF00657.17 KNZ77495.1 - 0.00064 19.6 1.4 0.0013 18.5 1.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Motile_Sperm PF00635.21 KNZ77496.1 - 2.7e-26 91.3 0.1 1.3e-25 89.1 0.0 2.0 1 1 1 2 2 2 1 MSP (Major sperm protein) domain SOBP PF15279.1 KNZ77496.1 - 1.3 9.3 15.5 1.8 8.8 10.7 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein ABC_membrane PF00664.18 KNZ77497.1 - 2.3e-91 306.0 27.3 2.7e-48 164.7 7.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KNZ77497.1 - 4.6e-69 231.0 0.1 2.8e-33 115.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KNZ77497.1 - 6.3e-15 55.0 0.4 7.7e-05 22.0 0.0 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KNZ77497.1 - 4.4e-14 53.1 0.2 0.00025 21.1 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KNZ77497.1 - 1.8e-08 33.7 1.6 0.0034 16.8 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KNZ77497.1 - 3.3e-08 33.7 4.4 5.9e-05 23.1 0.2 3.1 3 0 0 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.4 KNZ77497.1 - 3.4e-08 32.5 1.4 0.00071 18.2 0.0 3.2 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 KNZ77497.1 - 7.4e-07 30.0 0.0 0.034 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KNZ77497.1 - 5.8e-06 25.5 0.0 0.082 12.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KNZ77497.1 - 1.6e-05 25.0 2.7 0.35 11.0 0.2 4.2 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KNZ77497.1 - 2e-05 24.2 1.2 0.94 9.0 0.2 4.0 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 KNZ77497.1 - 0.00017 21.9 0.0 0.19 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KNZ77497.1 - 0.00024 20.9 0.0 0.52 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KNZ77497.1 - 0.00026 20.8 3.1 0.64 9.9 0.2 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.15 KNZ77497.1 - 0.00026 19.8 0.1 0.12 10.9 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_25 PF13481.1 KNZ77497.1 - 0.00037 19.9 0.1 1.5 8.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 KNZ77497.1 - 0.00084 19.0 0.5 1.3 8.7 0.0 3.0 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KNZ77497.1 - 0.00089 18.4 0.0 0.87 8.6 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_23 PF13476.1 KNZ77497.1 - 0.0013 19.1 0.1 3.3 7.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 KNZ77497.1 - 0.0036 16.8 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 KNZ77497.1 - 0.0047 16.7 0.5 5.8 6.6 0.0 3.6 4 0 0 4 4 3 0 Domain of unknown function DUF87 AAA_5 PF07728.9 KNZ77497.1 - 0.0054 16.4 0.1 2.9 7.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 KNZ77497.1 - 0.0065 16.4 0.1 4.6 7.2 0.0 3.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF815 PF05673.8 KNZ77497.1 - 0.0076 15.1 0.0 1.6 7.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) APS_kinase PF01583.15 KNZ77497.1 - 0.0091 15.6 0.1 5.6 6.6 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.1 KNZ77497.1 - 0.0094 15.9 0.1 3.2 7.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.1 KNZ77497.1 - 0.011 14.3 0.0 0.27 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_10 PF12846.2 KNZ77497.1 - 0.012 15.0 1.5 5.7 6.2 0.0 3.5 4 0 0 4 4 3 0 AAA-like domain AAA_15 PF13175.1 KNZ77497.1 - 0.012 14.6 0.0 5.6 5.8 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain PRK PF00485.13 KNZ77497.1 - 0.031 13.8 0.0 4.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 KNZ77497.1 - 0.14 11.0 0.0 2.9 6.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.18 KNZ77497.1 - 0.15 11.8 0.9 15 5.3 0.0 3.0 3 0 0 3 3 3 0 Dynamin family Pkinase PF00069.20 KNZ77498.1 - 2.3e-69 233.4 0.0 2.8e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77498.1 - 6.6e-30 104.0 0.0 8.8e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KNZ77498.1 - 7.2e-08 32.8 3.7 1.4e-07 31.9 2.5 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KNZ77498.1 - 0.00014 20.9 0.0 0.00036 19.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KNZ77498.1 - 0.033 13.2 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ77498.1 - 0.035 13.8 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family G-patch PF01585.18 KNZ77499.1 - 5e-06 26.1 0.0 0.00015 21.4 0.0 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KNZ77499.1 - 0.024 14.4 0.1 1.1 9.1 0.0 2.8 2 0 0 2 2 2 0 DExH-box splicing factor binding site F-box-like PF12937.2 KNZ77500.1 - 2.1e-09 36.9 1.8 7.7e-09 35.1 0.0 2.9 4 0 0 4 4 4 1 F-box-like PQ-loop PF04193.9 KNZ77501.1 - 2.1e-23 81.5 14.4 7.6e-18 63.8 0.4 3.8 4 0 0 4 4 4 3 PQ loop repeat MutS_V PF00488.16 KNZ77502.1 - 3.4e-41 141.1 0.0 8.5e-34 116.9 0.0 2.5 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.13 KNZ77502.1 - 3.9e-38 131.2 0.1 1e-37 129.9 0.1 1.7 1 0 0 1 1 1 1 MutS domain III Band_7 PF01145.20 KNZ77502.1 - 7e-20 71.6 0.6 1.3e-19 70.7 0.4 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Mito_carr PF00153.22 KNZ77503.1 - 6e-19 67.5 0.2 1.1e-09 37.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cyclin_N PF00134.18 KNZ77504.1 - 6.4e-12 45.1 0.0 1.9e-11 43.6 0.0 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain DUF4129 PF13559.1 KNZ77504.1 - 0.059 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Cyclin_C PF02984.14 KNZ77504.1 - 0.28 11.1 2.8 0.42 10.5 0.0 2.6 3 1 0 3 3 3 0 Cyclin, C-terminal domain zf-CSL PF05207.8 KNZ77505.1 - 4.3e-14 51.7 0.7 8.2e-14 50.8 0.5 1.5 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_5 PF13719.1 KNZ77505.1 - 0.062 12.8 0.2 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Pkinase PF00069.20 KNZ77506.1 - 2.2e-53 181.0 0.0 3.1e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77506.1 - 3e-28 98.6 0.0 2.8e-25 88.8 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KNZ77506.1 - 9.4e-08 31.3 0.0 1.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KNZ77506.1 - 0.0046 16.3 0.2 0.0074 15.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KNZ77506.1 - 0.0083 15.8 0.1 0.1 12.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family NOA36 PF06524.7 KNZ77506.1 - 0.056 12.6 7.6 0.11 11.7 5.2 1.4 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 KNZ77506.1 - 1.2 6.9 10.6 1.8 6.3 7.3 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KNZ77506.1 - 1.5 8.2 14.5 0.48 9.9 7.3 1.9 2 0 0 2 2 2 0 Nucleoplasmin ADH_zinc_N PF00107.21 KNZ77507.1 - 1.2e-12 47.4 0.0 2.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ77507.1 - 9.1e-12 44.7 0.0 1.5e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2651 PF10852.3 KNZ77507.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2651) DDE_1 PF03184.14 KNZ77508.1 - 0.00018 20.7 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Mvb12 PF09452.5 KNZ77508.1 - 0.13 12.4 0.1 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 APH PF01636.18 KNZ77510.1 - 2.1e-05 24.3 0.2 0.00085 19.1 0.1 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ77510.1 - 0.0021 17.2 0.0 0.0052 15.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain RPT PF13446.1 KNZ77510.1 - 0.21 11.0 1.6 1.8 8.0 0.1 2.7 3 0 0 3 3 3 0 A repeated domain in UCH-protein RNase_H PF00075.19 KNZ77511.1 - 1.7e-11 44.5 0.1 2.9e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RNase H DUF718 PF05336.8 KNZ77511.1 - 4.6 7.0 8.2 0.12 12.1 0.8 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF718) Alpha_kinase PF02816.13 KNZ77517.1 - 1.2e-07 31.6 0.7 2.6e-07 30.4 0.1 1.8 2 0 0 2 2 2 1 Alpha-kinase family Aminotran_1_2 PF00155.16 KNZ77518.1 - 7.6e-17 61.2 0.0 9.1e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KNZ77518.1 - 1.9e-09 36.5 0.0 2.4e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase ADH_zinc_N PF00107.21 KNZ77519.1 - 1.7e-13 50.2 0.0 3.1e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ77519.1 - 1.4e-09 37.6 0.0 2.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KNZ77519.1 - 0.0016 19.3 0.0 0.0027 18.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-CCHC PF00098.18 KNZ77520.1 - 0.01 15.7 0.7 0.028 14.3 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 KNZ77520.1 - 0.037 13.5 0.2 0.085 12.3 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle DSPc PF00782.15 KNZ77525.1 - 3.7e-26 91.2 0.0 3.5e-22 78.4 0.0 3.0 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KNZ77525.1 - 0.025 13.9 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KNZ77525.1 - 0.15 12.0 0.1 0.75 9.8 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF2415 PF10313.4 KNZ77526.1 - 1.3e-06 27.9 0.0 3.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 KNZ77526.1 - 0.03 14.1 10.9 4.4 7.3 0.1 5.2 5 0 0 5 5 5 0 WD domain, G-beta repeat PD40 PF07676.7 KNZ77526.1 - 0.052 13.2 1.3 10 5.8 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat GHMP_kinases_N PF00288.21 KNZ77528.1 - 9.4e-14 51.2 1.8 3e-13 49.6 0.9 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GalKase_gal_bdg PF10509.4 KNZ77528.1 - 1.6e-13 49.7 0.3 5.2e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 KNZ77528.1 - 1.8e-05 24.8 0.7 4.7e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal UPF0014 PF03649.8 KNZ77529.1 - 4e-40 137.5 12.2 5.6e-40 137.0 8.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) BPD_transp_1 PF00528.17 KNZ77529.1 - 0.00029 20.4 13.3 0.00029 20.4 9.2 2.1 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component FtsX PF02687.16 KNZ77529.1 - 0.0079 15.9 7.8 0.0079 15.9 5.4 3.1 1 1 2 3 3 3 1 FtsX-like permease family UPF0149 PF03695.8 KNZ77529.1 - 0.13 12.1 0.2 0.22 11.4 0.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0149) PGG PF13962.1 KNZ77529.1 - 0.18 11.4 3.7 0.14 11.7 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function HSP20 PF00011.16 KNZ77530.1 - 0.037 13.8 0.0 0.081 12.7 0.0 1.6 1 1 0 1 1 1 0 Hsp20/alpha crystallin family Flagellin_IN PF07196.8 KNZ77530.1 - 0.089 12.7 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Flagellin hook IN motif DUF1482 PF07358.6 KNZ77530.1 - 0.099 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) NAD_binding_8 PF13450.1 KNZ77531.1 - 7.8e-05 22.6 0.2 0.0031 17.4 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Ala_racemase_N PF01168.15 KNZ77532.1 - 1.5e-37 129.2 0.0 1.9e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain FAST_2 PF08368.7 KNZ77532.1 - 0.017 15.4 0.2 0.042 14.2 0.1 1.7 1 1 0 1 1 1 0 FAST kinase-like protein, subdomain 2 Glyco_transf_22 PF03901.12 KNZ77533.1 - 2.4e-39 135.5 25.3 2.9e-39 135.2 17.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ABC2_membrane PF01061.19 KNZ77534.1 - 7.5e-35 120.0 20.9 1.3e-34 119.2 14.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KNZ77534.1 - 1.8e-26 93.0 0.0 3e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KNZ77534.1 - 5.8e-09 36.3 0.1 9.7e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KNZ77534.1 - 0.00028 20.3 0.1 0.00072 19.0 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KNZ77534.1 - 0.0008 18.8 0.1 0.045 13.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KNZ77534.1 - 0.0012 18.1 0.1 0.0024 17.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 KNZ77534.1 - 0.0046 16.0 0.0 1.5 7.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain EGF_2 PF07974.8 KNZ77534.1 - 0.0072 16.4 11.1 0.0072 16.4 7.7 3.5 3 0 0 3 3 2 2 EGF-like domain AAA_28 PF13521.1 KNZ77534.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KNZ77534.1 - 0.027 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.14 KNZ77534.1 - 0.028 13.6 0.0 0.082 12.1 0.0 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ATP-synt_ab PF00006.20 KNZ77534.1 - 0.043 13.2 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.1 KNZ77534.1 - 0.044 13.9 0.1 0.14 12.2 0.0 1.9 3 0 0 3 3 1 0 AAA domain AAA_17 PF13207.1 KNZ77534.1 - 0.046 14.5 0.0 0.091 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.2 KNZ77534.1 - 0.057 12.4 29.1 0.2 10.6 20.2 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_33 PF13671.1 KNZ77534.1 - 0.071 12.9 0.1 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KNZ77534.1 - 0.076 12.6 0.2 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain ArgK PF03308.11 KNZ77534.1 - 0.1 11.3 0.2 0.21 10.3 0.1 1.4 1 0 0 1 1 1 0 ArgK protein SbcCD_C PF13558.1 KNZ77534.1 - 0.18 11.7 0.9 1.8 8.5 0.1 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.10 KNZ77534.1 - 0.24 10.0 0.0 0.35 9.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein hEGF PF12661.2 KNZ77534.1 - 0.45 10.7 31.3 0.4 10.8 4.3 5.0 4 0 0 4 4 4 0 Human growth factor-like EGF Laminin_EGF PF00053.19 KNZ77534.1 - 5.9 6.9 27.0 1.8 8.5 3.7 3.4 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) PIF1 PF05970.9 KNZ77535.1 - 7.1e-17 61.4 0.0 9.4e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase DUF262 PF03235.9 KNZ77536.1 - 1.7e-12 47.7 0.2 2.3e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF262 Pribosyltran_N PF13793.1 KNZ77538.1 - 6.2e-48 161.3 1.8 9.9e-47 157.4 0.1 3.1 2 1 1 4 4 4 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KNZ77538.1 - 1.4e-36 125.9 2.1 9.7e-34 116.7 0.7 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KNZ77538.1 - 1.1e-11 44.4 0.7 1.4e-10 40.9 0.5 2.4 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KNZ77538.1 - 1.2e-05 24.6 0.3 2.6e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 KNZ77538.1 - 0.049 12.9 0.2 0.091 12.0 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase TPR_11 PF13414.1 KNZ77540.1 - 1e-20 73.1 4.2 4.1e-15 55.1 0.9 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KNZ77540.1 - 1.5e-19 68.7 1.2 2.5e-06 26.8 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ77540.1 - 2.7e-17 61.2 5.5 1.8e-06 27.4 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ77540.1 - 9.9e-12 44.4 4.9 2e-05 24.8 0.4 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ77540.1 - 1.1e-09 38.6 2.6 1.5e-05 25.5 1.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ77540.1 - 1.2e-08 34.7 8.9 5.4e-06 26.2 0.7 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ77540.1 - 4.5e-08 33.2 2.1 2.1e-05 24.7 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ77540.1 - 3.2e-06 26.5 6.2 0.0025 17.4 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ77540.1 - 3.3e-06 26.4 0.5 0.052 13.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ77540.1 - 6.3e-06 26.3 3.8 0.021 15.2 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KNZ77540.1 - 0.00021 21.3 0.3 0.0035 17.4 0.1 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KNZ77540.1 - 0.00059 18.9 1.0 0.0015 17.6 0.7 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ77540.1 - 0.025 14.7 1.0 41 4.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ77540.1 - 0.094 12.5 7.1 1.1 9.1 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TEX19 PF15553.1 KNZ77541.1 - 0.08 12.7 1.2 0.41 10.5 0.3 1.9 1 1 1 2 2 2 0 Testis-expressed protein 19 RINGv PF12906.2 KNZ77543.1 - 1.1e-05 25.3 6.7 2e-05 24.5 4.7 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KNZ77543.1 - 0.00027 20.6 5.5 0.00046 19.9 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 KNZ77543.1 - 0.026 14.4 3.7 0.045 13.7 2.6 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.2 KNZ77543.1 - 0.068 13.2 4.6 0.14 12.3 3.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KNZ77543.1 - 0.14 11.8 3.5 0.23 11.1 2.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.1 KNZ77543.1 - 0.25 10.8 0.1 0.25 10.8 0.1 1.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.1 KNZ77543.1 - 0.25 11.3 4.8 1 9.4 3.2 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Hen1_L PF12623.2 KNZ77544.1 - 0.17 10.6 0.5 1.7 7.3 0.0 2.0 2 0 0 2 2 2 0 RNA repair, ligase-Pnkp-associating, region of Hen1 Mrr_cat_2 PF13156.1 KNZ77545.1 - 0.014 15.2 0.2 0.019 14.8 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease Botulinum_HA-17 PF05588.6 KNZ77545.1 - 0.057 13.3 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Clostridium botulinum HA-17 protein Aminotran_5 PF00266.14 KNZ77547.1 - 3.3e-07 29.3 0.0 4e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 KNZ77547.1 - 0.0047 16.7 0.0 0.0079 16.0 0.0 1.3 1 0 0 1 1 1 1 B12 binding domain Imm24 PF15570.1 KNZ77547.1 - 0.051 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 24 Aminotran_5 PF00266.14 KNZ77548.1 - 4.7e-13 48.6 0.1 5.7e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 KNZ77548.1 - 0.079 12.8 0.1 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain Cys_Met_Meta_PP PF01053.15 KNZ77550.1 - 1.1e-95 320.1 0.0 2.5e-95 319.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KNZ77550.1 - 9.1e-07 27.9 1.7 1.1e-06 27.7 0.5 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KNZ77550.1 - 2.2e-06 26.9 1.5 8.2e-06 25.0 1.0 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KNZ77550.1 - 7.3e-05 22.0 0.0 0.0002 20.5 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KNZ77550.1 - 0.001 18.1 0.2 0.0024 16.8 0.1 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.11 KNZ77550.1 - 0.04 12.6 0.0 0.069 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 KNZ77550.1 - 0.063 11.5 0.0 0.09 11.0 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase ThylakoidFormat PF11264.3 KNZ77551.1 - 0.027 14.1 0.0 0.033 13.7 0.0 1.0 1 0 0 1 1 1 0 Thylakoid formation protein Melibiase PF02065.13 KNZ77552.1 - 9.6e-19 67.3 0.1 4.2e-14 52.0 0.0 2.8 2 1 0 2 2 2 2 Melibiase E1_dh PF00676.15 KNZ77553.1 - 1.4e-111 372.0 0.0 1.7e-111 371.7 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KNZ77553.1 - 1.9e-05 23.7 0.0 2.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 KNZ77553.1 - 0.00069 19.2 0.6 0.00069 19.2 0.4 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Beta_elim_lyase PF01212.16 KNZ77553.1 - 0.0037 16.4 0.1 0.021 14.0 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase Transketolase_N PF00456.16 KNZ77553.1 - 0.085 11.6 0.2 0.17 10.6 0.0 1.6 2 0 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain RNase_P_Rpp14 PF01900.14 KNZ77554.1 - 3.1e-09 36.7 0.0 2.1e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Rpp14/Pop5 family GvpH PF05455.6 KNZ77555.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 GvpH zf-CCHC PF00098.18 KNZ77557.1 - 3e-05 23.7 2.0 8.2e-05 22.3 1.4 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 KNZ77557.1 - 0.0072 15.9 0.2 0.0072 15.9 0.1 1.8 2 0 0 2 2 2 1 Zinc knuckle Herpes_Helicase PF02689.9 KNZ77559.1 - 0.014 13.1 0.0 0.014 13.1 0.0 1.0 1 0 0 1 1 1 0 Helicase RNase_H PF00075.19 KNZ77561.1 - 1.5e-08 35.0 0.0 3.4e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-MYND PF01753.13 KNZ77562.1 - 2.6e-11 43.2 9.8 2.6e-11 43.2 6.8 1.9 2 0 0 2 2 2 1 MYND finger PPI_Ypi1 PF07491.6 KNZ77563.1 - 7.8e-24 83.0 2.6 7.8e-24 83.0 1.8 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor CDC45 PF02724.9 KNZ77563.1 - 0.0029 15.7 4.5 0.0034 15.5 3.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Zip PF02535.17 KNZ77563.1 - 0.061 12.3 3.2 0.059 12.3 2.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Marek_SORF3 PF07153.6 KNZ77563.1 - 0.12 11.0 1.1 0.15 10.7 0.8 1.1 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein S10_plectin PF03501.10 KNZ77564.1 - 1.2e-44 150.0 0.2 1.5e-44 149.7 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.14 KNZ77564.1 - 0.0055 16.3 0.0 0.01 15.5 0.0 1.5 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Aldose_epim PF01263.15 KNZ77565.1 - 1.7e-19 70.0 0.0 4.7e-09 35.7 0.0 2.9 1 1 1 2 2 2 2 Aldose 1-epimerase Myb_DNA-binding PF00249.26 KNZ77566.1 - 3.4e-34 116.6 4.7 4.8e-12 45.7 0.2 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KNZ77566.1 - 2.1e-28 98.2 0.3 3.3e-13 49.5 0.1 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KNZ77566.1 - 0.0036 17.4 5.9 0.2 11.8 0.6 3.2 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 KNZ77566.1 - 0.027 14.2 0.3 5.1 6.9 0.0 2.8 2 1 0 2 2 2 0 Rap1 Myb domain MADF_DNA_bdg PF10545.4 KNZ77566.1 - 0.037 14.2 1.2 1.6 8.9 0.1 2.8 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.1 KNZ77566.1 - 1.5 8.7 6.2 5.7 6.8 0.6 3.3 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain GMP_synt_C PF00958.17 KNZ77567.1 - 8.7e-38 127.9 0.1 1.7e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 KNZ77567.1 - 1.8e-36 125.4 0.0 3e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 KNZ77567.1 - 6.3e-10 38.3 0.2 9.7e-07 27.9 0.0 2.4 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 KNZ77567.1 - 1.5e-08 34.3 0.0 2.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 ThiI PF02568.9 KNZ77567.1 - 0.00062 19.2 0.1 0.0019 17.6 0.0 1.8 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 KNZ77567.1 - 0.0034 16.0 0.1 0.0055 15.3 0.1 1.3 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.8 KNZ77567.1 - 0.0062 15.8 0.0 0.014 14.6 0.0 1.6 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 KNZ77567.1 - 0.0067 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.15 KNZ77567.1 - 0.051 13.0 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Arginosuc_synth PF00764.14 KNZ77567.1 - 0.054 12.5 0.1 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.14 KNZ77567.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family XRN_N PF03159.13 KNZ77568.1 - 1.2e-94 316.1 0.0 2.2e-94 315.2 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Toxin_44 PF15523.1 KNZ77568.1 - 0.15 11.9 0.1 0.42 10.5 0.1 1.7 1 0 0 1 1 1 0 Putative toxin 44 ABC2_membrane_2 PF12679.2 KNZ77570.1 - 0.055 12.3 0.0 0.063 12.1 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4231 PF14015.1 KNZ77570.1 - 0.11 12.4 1.1 0.23 11.4 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF4514 PF14986.1 KNZ77570.1 - 0.36 10.6 1.7 0.78 9.6 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) Lon_C PF05362.8 KNZ77571.1 - 8.4e-68 227.7 0.1 1.5e-67 226.8 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KNZ77571.1 - 1.2e-35 123.1 0.1 2.6e-35 121.9 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KNZ77571.1 - 6.1e-22 78.2 0.0 2.3e-21 76.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KNZ77571.1 - 2.9e-07 30.2 0.0 5.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KNZ77571.1 - 1.3e-06 27.8 0.0 6.1e-06 25.7 0.0 2.2 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 KNZ77571.1 - 0.0002 21.2 0.0 0.00061 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KNZ77571.1 - 0.00023 21.9 0.3 0.00094 19.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ77571.1 - 0.00025 21.0 0.1 0.0022 18.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.6 KNZ77571.1 - 0.00098 17.9 0.0 0.0018 17.0 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.1 KNZ77571.1 - 0.0018 18.3 0.2 0.028 14.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KNZ77571.1 - 0.0039 16.2 0.0 0.02 13.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KNZ77571.1 - 0.0053 16.6 0.0 0.02 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KNZ77571.1 - 0.019 14.4 0.1 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KNZ77571.1 - 0.021 15.1 0.2 0.021 15.1 0.2 2.8 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.1 KNZ77571.1 - 0.029 14.3 2.5 0.32 10.9 0.1 2.9 2 1 1 3 3 3 0 AAA domain DUF258 PF03193.11 KNZ77571.1 - 0.044 12.9 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 KNZ77571.1 - 0.046 13.1 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SKI PF01202.17 KNZ77571.1 - 0.048 13.5 0.1 0.15 11.9 0.1 1.9 1 0 0 1 1 1 0 Shikimate kinase RNA_helicase PF00910.17 KNZ77571.1 - 0.053 13.6 0.1 0.69 10.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase UPF0079 PF02367.12 KNZ77571.1 - 0.16 11.5 0.1 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 KNZ77571.1 - 0.16 11.5 0.2 0.29 10.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KNZ77571.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain Phage_connect_1 PF05135.8 KNZ77571.1 - 0.51 10.5 3.6 1.4 9.1 0.1 2.9 3 0 0 3 3 3 0 Phage gp6-like head-tail connector protein ABC_tran PF00005.22 KNZ77571.1 - 0.7 10.1 3.1 0.65 10.2 0.6 2.1 2 0 0 2 2 2 0 ABC transporter TraV PF09676.5 KNZ77571.1 - 2.5 8.8 8.4 3.6 8.2 0.8 2.7 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Pex14_N PF04695.8 KNZ77571.1 - 2.8 7.9 13.1 2.4 8.2 2.9 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YibE_F PF07907.6 KNZ77572.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 YibE/F-like protein WD40 PF00400.27 KNZ77573.1 - 6.5e-196 628.1 64.5 1.4e-13 50.1 0.2 16.5 16 0 0 16 16 16 16 WD domain, G-beta repeat PD40 PF07676.7 KNZ77573.1 - 5.7e-24 83.3 33.5 0.99 9.1 0.0 15.2 16 0 0 16 16 14 13 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 KNZ77573.1 - 1.2e-11 43.5 12.7 0.00021 19.6 0.1 6.8 2 1 6 9 9 9 3 Cytochrome D1 heme domain NACHT PF05729.7 KNZ77573.1 - 1.3e-11 44.4 0.0 3e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF1258 PF06869.7 KNZ77573.1 - 6.7e-09 35.2 5.4 22 4.0 0.0 10.0 2 2 10 13 13 13 0 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 KNZ77573.1 - 4.6e-06 26.2 50.8 0.0015 18.0 11.1 4.6 1 1 2 3 3 3 2 PQQ-like domain AAA_16 PF13191.1 KNZ77573.1 - 1e-05 25.6 0.0 4.1e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KNZ77573.1 - 0.0043 15.9 0.7 0.016 14.0 0.0 2.3 3 0 0 3 3 3 1 NB-ARC domain ABC_tran PF00005.22 KNZ77573.1 - 0.0052 17.0 0.2 0.031 14.5 0.0 2.5 2 0 0 2 2 2 1 ABC transporter APS_kinase PF01583.15 KNZ77573.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 KNZ77573.1 - 0.0055 15.8 0.0 0.53 9.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 KNZ77573.1 - 0.013 15.6 0.0 0.072 13.2 0.0 2.3 1 0 0 1 1 1 0 AAA domain Proteasome_A_N PF10584.4 KNZ77573.1 - 0.017 14.4 33.1 1.5e+02 1.7 0.0 14.8 16 0 0 16 16 16 0 Proteasome subunit A N-terminal signature RNA_helicase PF00910.17 KNZ77573.1 - 0.024 14.7 0.2 0.29 11.3 0.0 3.1 2 0 0 2 2 1 0 RNA helicase AAA_23 PF13476.1 KNZ77573.1 - 0.037 14.3 7.0 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KNZ77573.1 - 0.073 12.8 0.0 0.36 10.6 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain D5_N PF08706.6 KNZ77573.1 - 0.11 12.5 1.3 0.52 10.3 0.3 2.6 2 0 0 2 2 2 0 D5 N terminal like AAA_17 PF13207.1 KNZ77573.1 - 0.13 13.1 0.2 2.4 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Abhydrolase_5 PF12695.2 KNZ77574.1 - 2e-23 82.7 0.0 4e-23 81.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ77574.1 - 1.2e-15 58.0 0.5 2.1e-13 50.7 0.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ77574.1 - 4.4e-08 32.9 0.2 9.8e-07 28.5 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KNZ77574.1 - 3.5e-06 26.4 0.0 8.4e-05 21.9 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 KNZ77574.1 - 7.5e-06 25.7 0.1 0.00082 19.1 0.0 2.9 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 KNZ77574.1 - 6.1e-05 22.5 0.0 1.4 8.2 0.0 3.1 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KNZ77574.1 - 0.00045 19.5 0.0 0.011 15.0 0.0 2.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.20 KNZ77574.1 - 0.0011 18.5 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF1057 PF06342.7 KNZ77574.1 - 0.0042 15.9 0.0 0.0058 15.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Esterase PF00756.15 KNZ77574.1 - 0.0064 15.9 0.0 0.012 15.0 0.0 1.5 2 0 0 2 2 2 1 Putative esterase Hydrolase_4 PF12146.3 KNZ77574.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase AXE1 PF05448.7 KNZ77574.1 - 0.014 13.8 0.1 0.029 12.8 0.0 1.5 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) PGAP1 PF07819.8 KNZ77574.1 - 0.032 13.8 0.1 0.046 13.2 0.1 1.4 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.8 KNZ77574.1 - 0.089 12.3 0.1 0.19 11.3 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.8 KNZ77574.1 - 0.097 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF2305 PF10230.4 KNZ77574.1 - 0.1 11.9 0.0 0.6 9.4 0.0 2.0 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2305) RdRP_2 PF00978.16 KNZ77575.1 - 0.011 14.3 0.2 0.015 14.0 0.2 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF2207 PF09972.4 KNZ77575.1 - 0.025 13.1 0.5 0.045 12.3 0.0 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Herpes_gE PF02480.11 KNZ77575.1 - 0.032 12.4 0.4 0.052 11.8 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1469 PF07332.6 KNZ77575.1 - 0.88 9.3 5.8 15 5.3 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) PARP PF00644.15 KNZ77576.1 - 0.059 12.7 0.2 0.35 10.2 0.1 1.9 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.15 KNZ77577.1 - 1.2e-14 54.2 1.8 2.5e-12 46.6 1.2 2.8 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.15 KNZ77578.1 - 2.7e-11 43.2 1.3 9.4e-09 34.9 0.5 2.4 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain C5-epim_C PF06662.8 KNZ77578.1 - 0.1 11.8 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus PARP PF00644.15 KNZ77579.1 - 5.8e-14 52.0 8.4 3e-13 49.6 0.3 3.1 2 2 1 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain S_locus_glycop PF00954.15 KNZ77579.1 - 0.32 11.2 5.9 0.088 13.0 1.2 2.2 2 1 1 3 3 3 0 S-locus glycoprotein family PARP PF00644.15 KNZ77580.1 - 5.1e-12 45.6 0.2 5.7e-08 32.4 0.0 3.0 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.6 KNZ77581.1 - 3.7e-29 101.4 0.0 4.9e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Cwf_Cwc_15 PF04889.7 KNZ77584.1 - 0.0027 17.4 2.7 0.0032 17.2 1.9 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.8 KNZ77584.1 - 0.01 15.4 6.6 0.017 14.7 4.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2722 PF10846.3 KNZ77584.1 - 0.61 9.0 5.9 0.85 8.5 4.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2722) PBP1_TM PF14812.1 KNZ77584.1 - 0.79 10.0 6.3 1.5 9.1 4.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HBS1_N PF08938.5 KNZ77584.1 - 1.5 8.9 9.6 3.1 7.9 6.6 1.4 1 0 0 1 1 1 0 HBS1 N-terminus TauD PF02668.11 KNZ77585.1 - 8.7e-42 143.5 0.0 1.1e-41 143.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KNZ77585.1 - 0.0017 17.3 0.0 0.045 12.6 0.0 2.1 2 0 0 2 2 2 1 CsiD rve PF00665.21 KNZ77585.1 - 0.0081 16.2 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain 2OG-FeII_Oxy_3 PF13640.1 KNZ77585.1 - 0.03 14.8 0.1 0.12 12.8 0.0 2.0 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily IlvN PF07991.7 KNZ77586.1 - 1.5e-45 154.5 0.0 2.9e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KNZ77586.1 - 1.3e-42 145.1 0.0 2.1e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Whi5 PF08528.6 KNZ77587.1 - 6.2e-07 28.8 0.9 1.2e-06 27.9 0.6 1.5 1 0 0 1 1 1 1 Whi5 like NUDIX PF00293.23 KNZ77588.1 - 3.4e-17 62.3 0.0 4.9e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Spc7 PF08317.6 KNZ77589.1 - 0.027 13.1 3.5 0.04 12.5 2.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein WD40_alt PF14077.1 KNZ77589.1 - 0.07 12.7 0.8 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF848 PF05852.6 KNZ77589.1 - 0.17 11.7 3.5 0.41 10.4 2.5 1.6 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) HALZ PF02183.13 KNZ77589.1 - 0.23 11.2 4.4 4.3 7.1 1.1 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 KNZ77589.1 - 0.46 10.4 2.9 7 6.6 0.2 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 KNZ77589.1 - 0.79 9.2 9.9 2.5 7.6 2.4 2.7 2 1 1 3 3 3 0 Septum formation initiator DUF904 PF06005.7 KNZ77589.1 - 3 8.2 10.2 24 5.2 7.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 KNZ77589.1 - 6.6 7.1 7.0 20 5.5 4.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Vps26 PF03643.10 KNZ77590.1 - 4.7e-25 87.9 0.5 6.1e-18 64.5 0.0 2.2 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 RNase_H PF00075.19 KNZ77590.1 - 6.6e-08 32.9 0.1 1.1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 RNase H Voldacs PF03517.8 KNZ77591.1 - 3.4e-29 101.3 0.0 3.4e-29 101.3 0.0 2.6 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling Auts2 PF15336.1 KNZ77591.1 - 0.11 12.4 0.4 0.21 11.6 0.2 1.4 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Pkinase PF00069.20 KNZ77592.1 - 5.7e-38 130.5 0.0 8.2e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77592.1 - 1e-33 116.4 0.0 1.6e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ77592.1 - 0.00055 18.9 0.0 0.00089 18.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SH3_9 PF14604.1 KNZ77593.1 - 6.4e-14 51.2 0.1 9.4e-14 50.7 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KNZ77593.1 - 1.4e-13 49.9 0.1 2.1e-13 49.4 0.1 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KNZ77593.1 - 2.4e-12 46.1 0.0 3.9e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.20 KNZ77594.1 - 1.5e-21 76.7 0.0 6.6e-19 68.0 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77594.1 - 2.2e-20 72.8 0.0 3e-17 62.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase DEAD PF00270.24 KNZ77596.1 - 1.5e-08 34.3 0.1 3e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KNZ77596.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Pkinase_Tyr PF07714.12 KNZ77597.1 - 7.4e-18 64.5 0.0 8.9e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ77597.1 - 1.3e-17 63.8 0.0 1.5e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KNZ77597.1 - 0.077 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KNZ77597.1 - 0.077 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF1349 PF07081.6 KNZ77598.1 - 5.2e-11 42.2 0.0 9e-11 41.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) PLAC8 PF04749.12 KNZ77599.1 - 3.4e-23 82.2 10.7 4.4e-23 81.8 7.4 1.1 1 0 0 1 1 1 1 PLAC8 family AMP-binding PF00501.23 KNZ77600.1 - 5.4e-33 114.0 0.0 2.1e-32 112.0 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KNZ77600.1 - 2.3e-20 72.6 0.0 3.4e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KNZ77600.1 - 0.00028 21.0 0.2 0.00096 19.3 0.1 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 KNZ77600.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PLAC8 PF04749.12 KNZ77602.1 - 6e-22 78.2 12.0 7.5e-22 77.9 8.3 1.1 1 0 0 1 1 1 1 PLAC8 family Ammonium_transp PF00909.16 KNZ77603.1 - 2e-117 392.0 29.7 2.3e-117 391.8 20.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family MFS_1 PF07690.11 KNZ77606.1 - 2.4e-43 148.1 49.2 4.3e-43 147.3 34.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ77606.1 - 8.1e-16 57.6 12.3 8.1e-16 57.6 8.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3460 PF11943.3 KNZ77607.1 - 0.032 14.3 0.1 0.056 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) Pkinase PF00069.20 KNZ77608.1 - 7.8e-43 146.4 0.0 1.2e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77608.1 - 2.1e-39 135.1 0.0 3.3e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ77608.1 - 0.018 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KNZ77608.1 - 0.045 13.4 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Chs3p PF12271.3 KNZ77609.1 - 7.3e-10 38.2 0.5 8.9e-06 24.8 0.1 2.1 2 0 0 2 2 2 2 Chitin synthase III catalytic subunit VMA21 PF09446.5 KNZ77609.1 - 0.023 14.6 0.9 5.4 7.0 0.2 2.5 2 0 0 2 2 2 0 VMA21-like domain PIF1 PF05970.9 KNZ77611.1 - 8.1e-40 136.8 0.0 1.1e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ77611.1 - 0.0019 17.7 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ77611.1 - 0.017 15.1 0.1 0.066 13.1 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.13 KNZ77611.1 - 0.03 13.8 0.2 0.066 12.7 0.2 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KNZ77611.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PIF1 PF05970.9 KNZ77612.1 - 3.1e-33 115.2 0.0 3.4e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase RVP_2 PF08284.6 KNZ77613.1 - 0.0019 18.1 0.0 0.0042 17.0 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease ATG13 PF10033.4 KNZ77614.1 - 4.6e-15 55.6 0.0 8.8e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 DUF4106 PF13388.1 KNZ77614.1 - 1.3 7.8 3.6 2.4 7.0 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Aldose_epim PF01263.15 KNZ77615.1 - 2.4e-60 204.1 0.7 3.4e-60 203.7 0.5 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Adeno_E3_CR2 PF02439.10 KNZ77616.1 - 2.3 7.8 7.7 1.4 8.5 1.2 3.5 3 0 0 3 3 3 0 Adenovirus E3 region protein CR2 Pkinase PF00069.20 KNZ77617.1 - 3.1e-39 134.6 0.0 4.8e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77617.1 - 1e-38 132.9 0.0 1.7e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KNZ77617.1 - 0.00062 18.8 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ77617.1 - 0.025 14.3 0.4 0.066 12.9 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KNZ77617.1 - 0.082 11.8 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 KNZ77617.1 - 0.093 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family DUF2554 PF10829.3 KNZ77618.1 - 0.076 13.1 0.2 7.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2554) BTB PF00651.26 KNZ77619.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Cu-oxidase PF00394.17 KNZ77620.1 - 1.8e-45 154.7 1.7 2e-41 141.5 0.4 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KNZ77620.1 - 6.3e-39 132.6 1.5 1.6e-37 128.1 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KNZ77620.1 - 2e-27 95.2 1.4 8.8e-26 89.9 0.4 2.7 2 0 0 2 2 2 1 Multicopper oxidase Sugar_tr PF00083.19 KNZ77621.1 - 1.1e-112 376.9 21.9 1.3e-112 376.7 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ77621.1 - 1.5e-24 86.3 25.7 1.5e-24 86.3 17.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Cu-oxidase PF00394.17 KNZ77623.1 - 6.3e-49 165.9 0.1 6.3e-45 152.9 0.0 3.1 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KNZ77623.1 - 1.1e-35 121.9 0.1 3.4e-33 113.8 0.0 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KNZ77623.1 - 1.2e-33 115.5 2.8 1.1e-27 96.2 0.1 3.9 3 1 0 3 3 3 2 Multicopper oxidase GMC_oxred_N PF00732.14 KNZ77625.1 - 1.4e-33 116.3 0.0 1.8e-32 112.6 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ77625.1 - 5e-07 30.1 0.0 8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KNZ77625.1 - 1.4e-05 25.0 0.0 2.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KNZ77625.1 - 1.8e-05 23.8 0.1 4.3e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ77625.1 - 0.00033 19.6 0.0 0.00068 18.5 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KNZ77625.1 - 0.0029 16.5 0.0 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 KNZ77625.1 - 0.0074 15.3 0.1 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KNZ77625.1 - 0.034 14.0 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KNZ77625.1 - 0.038 12.4 0.0 0.056 11.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KNZ77625.1 - 0.039 13.0 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KNZ77625.1 - 0.054 13.9 0.7 0.11 12.9 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 KNZ77625.1 - 0.073 11.3 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor GIDA PF01134.17 KNZ77625.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_2 PF00891.13 KNZ77626.1 - 8e-28 97.2 0.0 3.2e-27 95.2 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 KNZ77626.1 - 0.00069 20.0 0.0 0.015 15.8 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ77626.1 - 0.0015 19.0 0.0 0.003 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 KNZ77626.1 - 0.039 13.2 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Myco_arth_vir_N PF09610.5 KNZ77628.1 - 5.5 7.0 10.6 7 6.6 0.3 3.1 3 0 0 3 3 3 0 Mycoplasma virulence signal region (Myco_arth_vir_N) CBM_14 PF01607.19 KNZ77628.1 - 9.9 6.1 9.0 24 4.9 0.6 3.0 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain Cu-oxidase PF00394.17 KNZ77629.1 - 2.7e-48 163.8 0.0 1.1e-44 152.1 0.0 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KNZ77629.1 - 4.5e-37 126.3 0.0 5.2e-35 119.7 0.0 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KNZ77629.1 - 1.9e-32 111.6 2.7 9.3e-28 96.4 0.1 3.9 3 1 0 3 3 3 2 Multicopper oxidase HAD_2 PF13419.1 KNZ77630.1 - 1.5e-20 74.1 0.0 4.4e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Prenyltrans_2 PF13249.1 KNZ77630.1 - 0.00027 21.3 0.1 0.16 12.4 0.1 3.1 2 1 1 3 3 3 1 Prenyltransferase-like Hydrolase_like PF13242.1 KNZ77630.1 - 0.0027 17.3 0.0 0.0061 16.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2608 PF11019.3 KNZ77630.1 - 0.11 11.4 0.1 2.2 7.2 0.0 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2608) Herpes_Helicase PF02689.9 KNZ77633.1 - 1e-07 30.1 0.0 1.1e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ77633.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.4 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain ThylakoidFormat PF11264.3 KNZ77634.1 - 0.04 13.5 0.0 0.057 13.0 0.0 1.1 1 0 0 1 1 1 0 Thylakoid formation protein MFS_1 PF07690.11 KNZ77635.1 - 1.3e-34 119.5 45.0 1.3e-34 119.5 31.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Nic96 PF04097.9 KNZ77637.1 - 8.8e-30 103.4 1.6 1.1e-29 103.0 1.1 1.0 1 0 0 1 1 1 1 Nup93/Nic96 DUF3450 PF11932.3 KNZ77639.1 - 0.035 13.3 10.3 0.051 12.8 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Atg14 PF10186.4 KNZ77639.1 - 0.08 11.8 5.2 0.11 11.4 3.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 KNZ77639.1 - 0.12 12.4 8.8 1.1 9.2 6.1 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prp19 PF08606.6 KNZ77639.1 - 0.82 9.4 5.8 1.3 8.8 4.0 1.3 1 0 0 1 1 1 0 Prp19/Pso4-like DUF4407 PF14362.1 KNZ77639.1 - 1.2 7.9 8.6 1.9 7.3 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cep57_CLD_2 PF14197.1 KNZ77639.1 - 1.3 9.0 9.7 4.9 7.1 6.8 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF883 PF05957.8 KNZ77639.1 - 3.5 8.0 9.6 1.5e+02 2.8 6.7 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) IncA PF04156.9 KNZ77639.1 - 3.8 7.0 12.7 5.4 6.5 8.8 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 KNZ77639.1 - 4.1 7.7 6.9 4.6 7.6 3.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Nic96 PF04097.9 KNZ77640.1 - 3.6e-32 111.2 1.1 4.2e-32 111.0 0.8 1.0 1 0 0 1 1 1 1 Nup93/Nic96 His_kinase PF06580.8 KNZ77641.1 - 0.059 13.2 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase Helitron_like_N PF14214.1 KNZ77642.1 - 9.4e-16 58.0 0.1 1.2e-15 57.7 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ77642.1 - 0.014 14.9 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) Gemini_AL1 PF00799.15 KNZ77642.1 - 0.017 14.9 0.1 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain PIF1 PF05970.9 KNZ77644.1 - 3.4e-08 32.8 0.0 3.4e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase GWT1 PF06423.7 KNZ77645.1 - 0.0071 16.4 0.1 0.22 11.6 0.0 2.0 1 1 1 2 2 2 2 GWT1 Herpes_LAMP2 PF06126.6 KNZ77645.1 - 0.023 13.1 0.0 0.024 13.0 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Vps26 PF03643.10 KNZ77646.1 - 3.5e-12 45.6 0.0 3.8e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Pkinase PF00069.20 KNZ77649.1 - 0.0017 17.5 0.0 0.0034 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77649.1 - 0.0052 15.8 0.0 0.0092 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3384 PF11864.3 KNZ77650.1 - 0.026 12.9 0.0 0.026 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) NSP10 PF09401.5 KNZ77650.1 - 0.027 14.2 0.0 0.05 13.3 0.0 1.5 1 1 0 1 1 1 0 RNA synthesis protein NSP10 M157 PF11624.3 KNZ77651.1 - 0.055 12.5 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 MHC class I-like protein M157 Aldedh PF00171.17 KNZ77655.1 - 2.1e-23 82.4 2.5 5.8e-18 64.4 0.4 2.9 1 1 1 2 2 2 2 Aldehyde dehydrogenase family EFG_C PF00679.19 KNZ77656.1 - 1.2e-29 102.0 0.0 8e-15 54.4 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KNZ77656.1 - 9.8e-07 28.8 5.9 8.3e-05 22.6 0.8 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 RHSP PF07999.6 KNZ77656.1 - 0.002 16.8 0.1 1.2 7.6 0.0 2.1 2 0 0 2 2 2 2 Retrotransposon hot spot protein Zn_protease PF05618.6 KNZ77656.1 - 0.015 15.0 0.0 7 6.3 0.0 2.2 2 0 0 2 2 2 0 Putative ATP-dependant zinc protease Corona_I PF03187.9 KNZ77656.1 - 0.019 14.1 0.1 6.3 5.8 0.0 2.2 2 0 0 2 2 2 0 Corona nucleocapsid I protein EFG_II PF14492.1 KNZ77656.1 - 0.062 13.1 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Elongation Factor G, domain II TPR_12 PF13424.1 KNZ77657.1 - 6.6e-08 32.3 5.9 0.0033 17.3 0.1 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.17 KNZ77657.1 - 1.4e-07 30.7 0.1 2.3e-06 26.6 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain AAA_22 PF13401.1 KNZ77657.1 - 4.7e-07 30.0 0.1 3.3e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain TPR_16 PF13432.1 KNZ77657.1 - 4.7e-07 30.2 8.2 0.00044 20.8 0.2 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ77657.1 - 3.8e-05 23.9 6.8 0.19 12.1 0.3 4.6 3 1 1 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.1 KNZ77657.1 - 0.00024 21.1 0.1 0.0016 18.4 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain RPN7 PF10602.4 KNZ77657.1 - 0.0023 17.3 0.3 1.8 7.9 0.0 3.4 3 1 1 4 4 4 1 26S proteasome subunit RPN7 TPR_2 PF07719.12 KNZ77657.1 - 0.0034 17.1 16.5 4.4 7.4 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ77657.1 - 0.0037 16.8 3.9 1 9.0 0.0 4.6 4 0 0 4 4 4 1 TPR repeat AAA PF00004.24 KNZ77657.1 - 0.0083 16.3 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TPR_8 PF13181.1 KNZ77657.1 - 0.025 14.3 5.9 9.5 6.2 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF258 PF03193.11 KNZ77657.1 - 0.095 11.8 0.0 0.25 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TPR_14 PF13428.1 KNZ77657.1 - 0.1 13.3 10.4 2.9 8.7 0.0 6.1 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ77657.1 - 0.46 10.4 2.5 1.7 8.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TerY-C PF15616.1 KNZ77658.1 - 0.023 14.6 1.7 0.12 12.3 0.1 2.0 1 1 1 2 2 2 0 TerY-C metal binding domain zf-RVT PF13966.1 KNZ77658.1 - 0.029 14.6 1.2 0.037 14.3 0.2 1.7 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.2 KNZ77658.1 - 0.056 13.2 3.2 0.12 12.2 2.2 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 KNZ77658.1 - 0.067 12.6 0.1 0.067 12.6 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Gmx_para_CXXCG PF09535.5 KNZ77658.1 - 0.11 11.4 0.3 0.12 11.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) DUF3039 PF11238.3 KNZ77658.1 - 0.18 11.3 1.3 0.37 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) zf-FPG_IleRS PF06827.9 KNZ77658.1 - 0.64 9.7 4.8 0.28 10.8 0.6 2.2 2 1 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-ribbon_3 PF13248.1 KNZ77658.1 - 1 8.6 5.2 0.6 9.3 1.6 2.2 2 1 0 2 2 2 0 zinc-ribbon domain zf-RING_3 PF14369.1 KNZ77658.1 - 1.5 8.8 7.5 1.4 8.9 0.6 3.0 2 1 1 3 3 3 0 zinc-finger NB-ARC PF00931.17 KNZ77660.1 - 7.1e-08 31.6 0.0 1.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KNZ77660.1 - 1.1e-06 28.7 0.0 3.1e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ77660.1 - 0.00014 21.8 0.2 0.0011 19.0 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.24 KNZ77660.1 - 0.0028 17.8 0.0 0.0076 16.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KNZ77660.1 - 0.022 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein MMR_HSR1 PF01926.18 KNZ77660.1 - 0.026 14.4 0.3 0.17 11.8 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 KNZ77660.1 - 0.037 13.2 0.0 0.079 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 KNZ77660.1 - 0.053 13.8 0.1 0.34 11.2 0.0 2.2 1 1 0 2 2 2 0 ABC transporter AAA_14 PF13173.1 KNZ77660.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KNZ77660.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Aldedh PF00171.17 KNZ77661.1 - 5.3e-35 120.6 0.2 2.1e-27 95.6 0.0 3.0 2 1 1 3 3 3 3 Aldehyde dehydrogenase family AAA_22 PF13401.1 KNZ77664.1 - 8.8e-08 32.3 1.5 2.9e-07 30.6 0.0 2.6 4 0 0 4 4 3 1 AAA domain TPR_2 PF07719.12 KNZ77664.1 - 1.3e-06 27.9 3.9 0.17 11.9 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.17 KNZ77664.1 - 5.4e-06 25.4 0.0 1.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.1 KNZ77664.1 - 1.4e-05 25.5 0.4 1.4 9.6 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ77664.1 - 2.9e-05 23.9 4.4 0.0016 18.3 0.1 3.7 2 1 0 3 3 3 1 Tetratricopeptide repeat AAA_16 PF13191.1 KNZ77664.1 - 5.3e-05 23.2 0.9 0.0019 18.1 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain TPR_8 PF13181.1 KNZ77664.1 - 0.0011 18.6 5.1 13 5.8 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.4 KNZ77664.1 - 0.0023 17.3 0.9 0.068 12.5 0.1 2.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 AAA PF00004.24 KNZ77664.1 - 0.0066 16.6 0.0 0.027 14.6 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TPR_11 PF13414.1 KNZ77664.1 - 0.024 14.2 0.1 0.024 14.2 0.1 3.1 3 0 0 3 3 3 0 TPR repeat DUF258 PF03193.11 KNZ77664.1 - 0.071 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PIF1 PF05970.9 KNZ77669.1 - 2.2e-08 33.4 0.9 9.6e-06 24.7 0.2 2.4 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KNZ77669.1 - 0.0026 17.3 0.9 0.35 10.4 0.0 2.7 1 1 2 3 3 3 2 AAA domain DUF3176 PF11374.3 KNZ77671.1 - 0.039 13.8 0.1 0.081 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) DUF4632 PF15451.1 KNZ77671.1 - 0.064 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) FtsX PF02687.16 KNZ77671.1 - 0.07 12.8 4.9 0.31 10.8 0.1 2.8 2 1 0 2 2 2 0 FtsX-like permease family ADH_zinc_N_2 PF13602.1 KNZ77672.1 - 0.0075 17.1 0.3 0.063 14.1 0.0 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ATP_bind_3 PF01171.15 KNZ77673.1 - 8.7e-19 67.7 0.0 1.3e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 KNZ77673.1 - 0.0014 18.9 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 KNZ77673.1 - 0.01 14.4 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DUF4428 PF14471.1 KNZ77673.1 - 0.013 15.2 0.5 0.029 14.1 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Sugar_tr PF00083.19 KNZ77674.1 - 1.7e-50 171.9 18.8 1.7e-49 168.6 13.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ77674.1 - 3.5e-19 68.7 27.7 3.5e-19 68.7 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L11_N PF03946.9 KNZ77675.1 - 0.0097 15.3 0.3 0.33 10.4 0.0 2.9 3 0 0 3 3 3 1 Ribosomal protein L11, N-terminal domain Methyltransf_2 PF00891.13 KNZ77676.1 - 3.5e-11 42.7 0.0 1.4e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase DUF3216 PF11505.3 KNZ77676.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) RNase_H PF00075.19 KNZ77677.1 - 2.2e-08 34.5 0.0 6.7e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.1 KNZ77677.1 - 0.0095 16.2 0.2 0.027 14.7 0.2 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.2 KNZ77677.1 - 0.048 13.4 0.5 0.13 12.0 0.3 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Exo_endo_phos_2 PF14529.1 KNZ77678.1 - 4.1e-08 32.8 0.6 1.2e-07 31.3 0.1 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KNZ77678.1 - 6.8e-05 22.9 1.5 9.4e-05 22.4 1.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cyclin PF08613.6 KNZ77683.1 - 2.4e-15 57.2 0.0 4.6e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 KNZ77683.1 - 1.1e-11 44.4 0.0 1.7e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Mito_carr PF00153.22 KNZ77684.1 - 8.9e-55 182.4 0.8 1.2e-20 72.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S9_N PF02897.10 KNZ77685.1 - 1.1e-85 287.7 8.3 1.4e-85 287.4 5.8 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 KNZ77685.1 - 1.4e-46 158.4 4.1 8.5e-32 110.1 0.1 2.7 2 1 1 3 3 3 2 Prolyl oligopeptidase family dCMP_cyt_deam_1 PF00383.17 KNZ77686.1 - 1.4e-21 75.9 0.1 2.2e-21 75.4 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KNZ77686.1 - 0.00024 20.9 1.5 0.012 15.4 1.0 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.6 KNZ77686.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain APH PF01636.18 KNZ77687.1 - 1e-08 35.2 0.0 2.4e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.19 KNZ77688.1 - 3.8e-27 95.2 2.1 6.1e-27 94.5 1.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KNZ77688.1 - 3.2e-18 64.9 1.7 8.6e-18 63.5 1.2 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 KNZ77688.1 - 4.7e-18 64.7 0.1 2.8e-17 62.2 0.0 2.3 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 KNZ77688.1 - 6e-10 39.6 0.0 2.1e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KNZ77688.1 - 0.00058 20.1 0.3 0.0013 18.9 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PIF1 PF05970.9 KNZ77689.1 - 5.1e-14 51.9 0.1 6.7e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase TraG_N PF07916.6 KNZ77689.1 - 0.0056 15.1 0.2 0.0067 14.9 0.1 1.0 1 0 0 1 1 1 1 TraG-like protein, N-terminal region ATP-synt_C PF00137.16 KNZ77690.1 - 2.2e-31 107.5 30.0 2.3e-18 65.8 9.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.3 KNZ77690.1 - 4.3 7.0 9.4 0.58 9.7 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Flavi_NS4A PF01350.12 KNZ77690.1 - 8.5 5.9 9.1 1.6 8.3 2.1 2.0 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A EHN PF06441.7 KNZ77691.1 - 4.7e-30 103.7 0.0 7.5e-30 103.1 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KNZ77691.1 - 1.4e-10 41.5 0.4 1.2e-09 38.4 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ77691.1 - 3.9e-07 29.8 0.0 1.5e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold SNF2_N PF00176.18 KNZ77692.1 - 8.1e-65 218.5 0.1 1.6e-64 217.5 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNZ77692.1 - 1e-11 44.5 0.0 2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 KNZ77692.1 - 2.2e-06 27.4 5.3 2.2e-06 27.4 3.7 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 KNZ77692.1 - 3.5e-06 26.5 5.8 3.5e-06 26.5 4.0 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ77692.1 - 4.3e-06 26.6 4.4 4.3e-06 26.6 3.0 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KNZ77692.1 - 0.00019 21.2 4.3 0.00019 21.2 3.0 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KNZ77692.1 - 0.0007 19.2 3.9 0.0007 19.2 2.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KNZ77692.1 - 0.00076 19.5 4.3 0.0027 17.7 3.0 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 KNZ77692.1 - 0.0011 18.4 4.0 0.0025 17.2 2.8 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 KNZ77692.1 - 0.0052 16.5 0.6 0.015 15.1 0.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KNZ77692.1 - 0.0057 16.3 1.4 0.016 14.8 0.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 KNZ77692.1 - 0.052 13.3 0.7 0.12 12.1 0.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Mito_carr PF00153.22 KNZ77693.1 - 2.5e-52 174.5 4.9 6e-19 67.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Spt4 PF06093.8 KNZ77694.1 - 1.3e-30 105.0 0.2 1.6e-30 104.8 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Lipase_3 PF01764.20 KNZ77695.1 - 1.6e-17 63.3 0.0 3.5e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KNZ77695.1 - 0.056 13.1 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family p450 PF00067.17 KNZ77696.1 - 3.3e-59 200.6 0.0 7.6e-59 199.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_M24 PF00557.19 KNZ77697.1 - 7.5e-54 182.4 0.0 1e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KNZ77697.1 - 1.4e-32 111.8 0.0 3.6e-32 110.5 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Adeno_PV PF03910.8 KNZ77698.1 - 0.024 13.7 0.0 0.026 13.5 0.0 1.0 1 0 0 1 1 1 0 Adenovirus minor core protein PV Chromo PF00385.19 KNZ77698.1 - 0.028 14.0 0.1 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF1509 PF07420.6 KNZ77699.1 - 0.003 16.9 4.1 0.0039 16.5 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) HMG_box PF00505.14 KNZ77703.1 - 4.2e-17 62.1 3.9 4.2e-17 62.1 2.7 2.1 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KNZ77703.1 - 7.7e-12 45.4 3.8 7.7e-12 45.4 2.7 2.1 2 1 0 2 2 2 1 HMG-box domain CHDNT PF08073.7 KNZ77703.1 - 0.0098 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain Med26 PF08711.6 KNZ77704.1 - 4.2e-09 35.7 0.3 9.7e-09 34.6 0.2 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain LIM_bind PF01803.11 KNZ77706.1 - 2e-54 184.2 0.0 4.1e-54 183.2 0.0 1.6 1 0 0 1 1 1 1 LIM-domain binding protein DUF2146 PF10220.4 KNZ77707.1 - 0.017 13.1 0.0 2.6 5.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2146) DUF1900 PF08954.6 KNZ77707.1 - 0.16 11.4 0.0 19 4.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1900) OTT_1508_deam PF14441.1 KNZ77708.1 - 1.3e-05 25.0 0.0 7.7e-05 22.5 0.0 1.9 1 1 0 2 2 2 1 OTT_1508-like deaminase OTT_1508_deam PF14441.1 KNZ77709.1 - 9.2e-08 31.9 0.0 5.2e-07 29.5 0.0 2.1 2 1 0 2 2 2 1 OTT_1508-like deaminase CDC48_2 PF02933.12 KNZ77709.1 - 0.022 14.4 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 TruB_C PF09142.6 KNZ77709.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal OTT_1508_deam PF14441.1 KNZ77710.1 - 4e-05 23.4 0.0 6.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase Ribosomal_S4 PF00163.14 KNZ77711.1 - 4.3e-13 49.4 1.0 5.9e-13 49.0 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KNZ77711.1 - 8e-11 41.2 0.0 1.4e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain Herpes_LAMP2 PF06126.6 KNZ77711.1 - 0.046 12.1 0.0 0.056 11.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 p450 PF00067.17 KNZ77712.1 - 8.3e-58 196.0 0.0 4.7e-56 190.2 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 KNZ77713.1 - 0.00018 20.7 0.0 0.00042 19.4 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain SAA PF00277.13 KNZ77713.1 - 0.18 12.2 0.0 0.31 11.4 0.0 1.3 1 0 0 1 1 1 0 Serum amyloid A protein Kinesin PF00225.18 KNZ77714.1 - 2.5e-103 345.3 0.0 3.9e-103 344.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 KNZ77714.1 - 2.5e-36 124.4 0.0 6e-36 123.1 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 KNZ77714.1 - 6.4e-13 48.8 0.0 2e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 PH domain KIF1B PF12423.3 KNZ77714.1 - 2.9e-07 30.4 0.8 6.6e-07 29.2 0.6 1.7 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 KNZ77714.1 - 1e-05 25.5 0.1 5.5e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 FHA domain CMAS PF02353.15 KNZ77715.1 - 8.8e-58 195.5 0.0 1.2e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KNZ77715.1 - 1.4e-07 31.3 0.0 2.5e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ77715.1 - 9.8e-07 29.3 0.0 2.4e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ77715.1 - 5.2e-05 23.6 0.0 0.00015 22.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ77715.1 - 0.0017 17.9 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ77715.1 - 0.0055 16.0 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KNZ77715.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ77715.1 - 0.019 14.9 0.1 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SAC3 PF12209.3 KNZ77715.1 - 0.041 14.0 0.0 0.091 12.9 0.0 1.6 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain DOT1 PF08123.8 KNZ77715.1 - 0.071 12.4 0.0 0.17 11.2 0.0 1.6 1 1 1 2 2 2 0 Histone methylation protein DOT1 Arf PF00025.16 KNZ77716.1 - 9.1e-71 236.6 0.1 1.1e-70 236.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KNZ77716.1 - 2.5e-14 52.8 1.0 2.5e-08 33.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KNZ77716.1 - 2.7e-10 39.8 0.0 3.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KNZ77716.1 - 1.6e-09 37.3 0.0 2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KNZ77716.1 - 5.3e-09 35.5 0.0 7.6e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KNZ77716.1 - 6.1e-08 32.6 0.0 8.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KNZ77716.1 - 6.8e-08 33.0 0.0 1.9e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KNZ77716.1 - 3.7e-05 23.2 0.0 0.0019 17.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KNZ77716.1 - 0.0099 15.3 0.1 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.13 KNZ77716.1 - 0.079 12.0 0.0 0.094 11.7 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase NACHT PF05729.7 KNZ77716.1 - 0.098 12.3 0.1 0.43 10.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.13 KNZ77716.1 - 0.11 11.7 0.1 0.23 10.6 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AA_permease_2 PF13520.1 KNZ77717.1 - 2.3e-43 148.3 54.6 3.1e-43 147.8 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease GTP_EFTU PF00009.22 KNZ77717.1 - 1.6e-32 112.4 0.0 6.5e-32 110.4 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AA_permease PF00324.16 KNZ77717.1 - 1.3e-21 76.5 47.0 1.8e-21 76.0 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease IF-2 PF11987.3 KNZ77717.1 - 9.1e-18 64.1 0.0 2.3e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KNZ77717.1 - 6.5e-15 55.0 3.0 3.6e-10 39.8 0.1 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KNZ77717.1 - 1.3e-06 28.3 0.6 4.9e-06 26.4 0.0 2.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KNZ77717.1 - 0.014 15.5 0.0 0.044 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 KNZ77717.1 - 0.018 14.6 0.0 0.046 13.2 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ras PF00071.17 KNZ77717.1 - 0.051 12.9 0.0 0.22 10.9 0.0 2.2 1 1 0 1 1 1 0 Ras family Pkinase PF00069.20 KNZ77718.1 - 1.1e-21 77.1 0.0 4.4e-12 45.6 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77718.1 - 7.6e-07 28.4 0.0 0.0021 17.2 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase EcKinase PF02958.15 KNZ77718.1 - 0.17 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase ICMT PF04140.9 KNZ77719.1 - 6e-13 48.8 1.5 2.5e-12 46.8 0.3 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KNZ77719.1 - 4.8e-11 42.7 2.0 2.3e-10 40.4 1.4 2.0 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KNZ77719.1 - 1.7e-06 26.8 0.1 2.8e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Acyl-CoA_dh_1 PF00441.19 KNZ77720.1 - 3.5e-46 157.0 1.2 5.2e-46 156.4 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KNZ77720.1 - 4.3e-29 101.3 0.2 1.8e-28 99.4 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KNZ77720.1 - 2.1e-21 76.5 0.3 3.8e-21 75.7 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KNZ77720.1 - 1.5e-20 72.4 0.0 2.7e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Ric8 PF10165.4 KNZ77721.1 - 9.3e-78 262.0 0.0 1.6e-77 261.2 0.0 1.4 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Med10 PF09748.4 KNZ77722.1 - 4.6e-20 71.7 0.1 5.7e-20 71.4 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PIN_4 PF13638.1 KNZ77722.1 - 0.021 14.9 0.1 0.026 14.6 0.1 1.2 1 0 0 1 1 1 0 PIN domain SAE2 PF08573.5 KNZ77725.1 - 3.4e-19 69.3 1.7 3.4e-19 69.3 1.2 4.2 5 1 0 5 5 5 1 DNA repair protein endonuclease SAE2/CtIP C-terminus HrpA_pilin PF09589.5 KNZ77725.1 - 0.1 12.9 4.0 2.1 8.7 0.2 2.8 2 0 0 2 2 2 0 HrpA pilus formation protein CorA PF01544.13 KNZ77725.1 - 1.3 8.0 7.9 4.5 6.2 5.5 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2235 PF09994.4 KNZ77730.1 - 1.3e-74 251.0 0.0 2.5e-74 250.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KNZ77730.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.6 KNZ77730.1 - 0.054 13.1 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3850 PF12961.2 KNZ77730.1 - 0.059 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3850) Thiolase_N PF00108.18 KNZ77731.1 - 0.04 12.8 0.0 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF4448 PF14610.1 KNZ77732.1 - 6.6e-15 55.0 0.0 1.1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 KNZ77732.1 - 0.00026 21.4 3.6 0.00029 21.2 1.1 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1880 PF08976.6 KNZ77732.1 - 0.088 12.9 2.6 0.73 9.9 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) Helitron_like_N PF14214.1 KNZ77733.1 - 2.3e-63 213.2 0.3 6.1e-63 211.8 0.1 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 KNZ77733.1 - 0.037 12.7 0.0 0.064 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) DUF3296 PF11726.3 KNZ77733.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) APH PF01636.18 KNZ77735.1 - 3e-11 43.4 1.3 3.7e-11 43.2 0.9 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ77735.1 - 0.0015 18.1 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KNZ77735.1 - 0.038 13.3 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Thiolase_N PF00108.18 KNZ77736.1 - 6.6e-61 205.5 1.6 1e-60 204.9 1.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KNZ77736.1 - 2.3e-30 104.5 0.9 4.6e-22 77.7 0.0 2.7 3 0 0 3 3 3 2 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KNZ77736.1 - 0.0025 17.3 0.5 0.013 15.0 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KNZ77736.1 - 0.054 13.1 0.4 13 5.5 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DASH_Hsk3 PF08227.6 KNZ77739.1 - 0.098 12.8 0.1 24 5.2 0.0 2.6 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like HAD_2 PF13419.1 KNZ77741.1 - 1.3e-29 103.6 0.0 3.3e-29 102.3 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KNZ77741.1 - 0.00021 20.9 0.0 0.00048 19.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Prenyltrans_2 PF13249.1 KNZ77741.1 - 0.00022 21.5 0.1 0.057 13.8 0.2 3.1 2 1 1 3 3 3 1 Prenyltransferase-like Hydrolase PF00702.21 KNZ77741.1 - 0.0058 17.0 0.0 0.024 15.0 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase GFA PF04828.9 KNZ77742.1 - 1.3e-10 41.0 0.0 1.3e-10 41.0 0.0 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF2026 PF09641.5 KNZ77742.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2026) AMP-binding PF00501.23 KNZ77743.1 - 1.8e-77 260.5 0.0 7e-77 258.5 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KNZ77743.1 - 2.4e-11 44.4 0.2 4.7e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.21 KNZ77745.1 - 9e-31 106.1 0.2 1.7e-30 105.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KNZ77745.1 - 5.5e-11 43.4 0.0 1.2e-10 42.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ77745.1 - 3e-09 36.6 0.0 6.4e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CoaE PF01121.15 KNZ77746.1 - 2.5e-66 222.4 0.0 3.1e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 KNZ77746.1 - 3.4e-07 30.6 0.0 5.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ77746.1 - 8.8e-06 26.5 0.4 5.5e-05 23.9 0.3 2.1 1 1 0 1 1 1 1 AAA domain DUF639 PF04842.7 KNZ77746.1 - 0.0062 14.7 0.5 0.054 11.6 0.1 2.0 1 1 1 2 2 2 1 Plant protein of unknown function (DUF639) PRK PF00485.13 KNZ77746.1 - 0.0086 15.6 0.4 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family Pox_mRNA-cap PF03341.8 KNZ77746.1 - 0.0088 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Poxvirus mRNA capping enzyme, small subunit HECT PF00632.20 KNZ77747.1 - 8e-91 304.4 0.0 1.5e-90 303.6 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 KNZ77747.1 - 4.2e-74 249.5 0.0 4.2e-74 249.5 0.0 3.6 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 KNZ77747.1 - 3.4e-66 223.8 1.0 1e-65 222.2 0.7 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 KNZ77747.1 - 2.6e-20 72.3 1.3 1.4e-19 69.9 0.9 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) UBA PF00627.26 KNZ77747.1 - 7.8e-12 44.6 0.3 4.3e-10 39.1 0.1 2.7 2 0 0 2 2 2 1 UBA/TS-N domain CUE PF02845.11 KNZ77747.1 - 0.014 14.8 0.1 0.11 11.9 0.0 2.5 2 0 0 2 2 2 0 CUE domain AKAP_110 PF05716.8 KNZ77747.1 - 0.032 12.2 0.1 0.065 11.2 0.0 1.4 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) Dpy-30 PF05186.8 KNZ77747.1 - 9.6 5.7 6.9 0.65 9.5 0.3 2.5 3 0 0 3 3 3 0 Dpy-30 motif FA_hydroxylase PF04116.8 KNZ77748.1 - 6.2e-12 45.9 22.0 6.2e-12 45.9 15.3 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily PC4 PF02229.11 KNZ77749.1 - 4.9e-20 70.5 0.1 7.5e-20 69.9 0.0 1.2 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) ABC1 PF03109.11 KNZ77750.1 - 6e-33 113.3 0.0 1.1e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 KNZ77750.1 - 0.00016 21.1 0.1 0.0012 18.1 0.0 2.0 2 0 0 2 2 2 1 RIO1 family DUF3467 PF11950.3 KNZ77751.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) APG6 PF04111.7 KNZ77752.1 - 3e-94 315.5 7.4 1.4e-79 267.4 3.3 2.4 1 1 1 2 2 2 2 Autophagy protein Apg6 FtsL PF04999.8 KNZ77752.1 - 0.038 13.6 8.9 0.049 13.3 5.0 1.9 2 0 0 2 2 2 0 Cell division protein FtsL V_ATPase_I PF01496.14 KNZ77752.1 - 0.1 10.4 4.8 0.13 10.0 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 KNZ77752.1 - 1.1 9.5 8.5 1.7 8.8 5.9 1.4 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 KNZ77752.1 - 1.7 6.9 8.3 2.3 6.5 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 KNZ77752.1 - 8.5 5.9 12.5 13 5.3 8.7 1.3 1 0 0 1 1 1 0 IncA protein DDE_1 PF03184.14 KNZ77753.1 - 1.1e-08 34.5 0.0 1.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Ham1p_like PF01725.11 KNZ77754.1 - 0.14 11.5 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Ham1 family Ehrlichia_rpt PF09528.5 KNZ77755.1 - 0.034 12.2 11.6 0.045 11.9 8.1 1.1 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) zf-CCHC PF00098.18 KNZ77757.1 - 0.0055 16.5 0.6 0.01 15.7 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle SLAIN PF15301.1 KNZ77758.1 - 0.27 10.3 2.8 0.29 10.2 1.9 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family Asp_protease_2 PF13650.1 KNZ77759.1 - 2e-06 28.1 0.0 4.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ77759.1 - 0.0055 16.2 0.1 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF4536 PF15055.1 KNZ77760.1 - 9e-07 28.8 1.2 9e-07 28.8 0.8 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4536) ECH PF00378.15 KNZ77761.1 - 4.2e-80 268.3 0.6 5.1e-80 268.1 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KNZ77761.1 - 0.0017 18.5 0.1 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 KNZ77761.1 - 0.0049 16.6 0.1 0.019 14.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase family S49 YCII PF03795.9 KNZ77762.1 - 7.3e-06 26.0 0.0 9.2e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain YCII PF03795.9 KNZ77763.1 - 5.3e-07 29.7 0.0 6.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain zf-C3HC4_3 PF13920.1 KNZ77764.1 - 0.1 12.2 0.5 0.98 9.1 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HIT PF04438.11 KNZ77764.1 - 0.19 11.3 1.8 0.69 9.6 0.2 2.0 2 0 0 2 2 2 0 HIT zinc finger zf-MIZ PF02891.15 KNZ77764.1 - 0.24 10.9 1.6 1.9 8.0 0.1 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Med12 PF09497.5 KNZ77765.1 - 1.2e-24 86.0 0.1 3.7e-24 84.4 0.0 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 DASH_Dad2 PF08654.5 KNZ77766.1 - 1.2e-10 41.2 0.1 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 WHEP-TRS PF00458.15 KNZ77766.1 - 0.079 12.6 0.5 0.13 11.9 0.3 1.3 1 0 0 1 1 1 0 WHEP-TRS domain DUF221 PF02714.10 KNZ77767.1 - 2.2e-73 246.9 17.2 4e-73 246.1 6.5 3.2 2 1 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KNZ77767.1 - 7.9e-28 96.9 7.6 1.3e-15 57.3 1.4 3.2 3 0 0 3 3 3 2 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KNZ77767.1 - 5.7e-16 58.8 0.2 5.7e-16 58.8 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 KNZ77767.1 - 4.9e-13 48.7 0.6 1.5e-12 47.2 0.1 2.0 2 0 0 2 2 2 1 Phosphate metabolism protein GP41 PF00517.12 KNZ77767.1 - 4.8 6.6 5.3 17 4.8 0.1 3.1 3 0 0 3 3 3 0 Retroviral envelope protein HEAT PF02985.17 KNZ77768.1 - 8.1e-08 31.7 0.5 0.57 10.4 0.0 5.2 5 0 0 5 5 5 3 HEAT repeat Pkinase PF00069.20 KNZ77768.1 - 8.7e-06 25.0 0.0 1.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77768.1 - 0.0018 17.3 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DS PF01916.12 KNZ77768.1 - 0.17 11.0 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Deoxyhypusine synthase Med14 PF08638.6 KNZ77769.1 - 8e-53 178.5 0.1 1.5e-52 177.6 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 Acetyltransf_1 PF00583.19 KNZ77771.1 - 1.9e-12 47.0 0.0 3.5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GIY-YIG PF01541.19 KNZ77771.1 - 2.7e-06 27.6 0.0 5.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain Acetyltransf_10 PF13673.1 KNZ77771.1 - 8.4e-05 22.6 0.0 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KNZ77771.1 - 0.00034 20.4 0.0 0.00082 19.2 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 KNZ77771.1 - 0.00073 19.6 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KNZ77771.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KNZ77771.1 - 0.016 15.3 0.0 0.06 13.5 0.0 2.0 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain PEPCK_ATP PF01293.15 KNZ77772.1 - 9.7e-217 720.0 0.0 1.2e-216 719.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DGOK PF05035.7 KNZ77772.1 - 0.019 13.6 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase AAA_29 PF13555.1 KNZ77772.1 - 0.027 13.9 0.0 0.077 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KNZ77772.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KNZ77772.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Dimer_Tnp_hAT PF05699.9 KNZ77773.1 - 3.6e-19 68.1 0.0 4.3e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PHD PF00628.24 KNZ77774.1 - 1.4e-07 31.0 5.0 7.4e-06 25.5 1.3 2.3 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.1 KNZ77774.1 - 0.0038 16.5 2.0 0.0038 16.5 1.4 1.6 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 KNZ77774.1 - 0.0054 16.4 3.0 0.0054 16.4 2.1 2.1 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KNZ77774.1 - 0.011 15.4 2.5 0.011 15.4 1.7 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KNZ77774.1 - 0.013 14.7 1.3 0.013 14.7 0.9 2.6 3 0 0 3 3 3 0 PHD-finger ADK_lid PF05191.9 KNZ77774.1 - 9.3 6.0 7.1 2.5 7.8 1.8 2.4 2 1 0 2 2 2 0 Adenylate kinase, active site lid DUF2976 PF11190.3 KNZ77775.1 - 0.022 14.2 0.2 0.063 12.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) DUF3353 PF11833.3 KNZ77775.1 - 0.33 10.3 7.3 0.42 10.0 0.6 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3353) DUF3415 PF11895.3 KNZ77776.1 - 8.9e-33 112.0 1.4 2e-32 110.9 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 KNZ77776.1 - 2.1e-27 96.1 0.0 2.9e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DNA_primase_S PF01896.14 KNZ77777.1 - 2e-41 141.2 0.1 3.1e-41 140.5 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DUF3349 PF11829.3 KNZ77778.1 - 0.094 13.1 0.4 0.25 11.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) Adaptin_N PF01602.15 KNZ77779.1 - 2.4e-20 72.3 1.8 2.3e-19 69.1 0.7 2.6 2 1 0 2 2 2 1 Adaptin N terminal region HEAT PF02985.17 KNZ77779.1 - 0.039 14.0 1.0 23 5.4 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat RabGAP-TBC PF00566.13 KNZ77780.1 - 1.1e-39 136.0 0.0 1.6e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain bZIP_1 PF00170.16 KNZ77781.1 - 0.00019 21.3 3.0 0.0004 20.2 2.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor ERM PF00769.14 KNZ77781.1 - 0.01 15.3 1.5 0.015 14.8 1.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family bZIP_2 PF07716.10 KNZ77781.1 - 0.34 10.7 7.4 0.066 13.0 2.5 1.8 2 0 0 2 2 2 0 Basic region leucine zipper IU_nuc_hydro PF01156.14 KNZ77782.1 - 1.4e-28 100.0 0.0 2.6e-28 99.1 0.0 1.4 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase WD40 PF00400.27 KNZ77783.1 - 1.8e-61 201.9 24.6 8.9e-12 44.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KNZ77783.1 - 0.0015 18.3 0.2 0.18 11.5 0.0 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KNZ77783.1 - 0.0017 16.5 8.6 0.36 8.8 0.6 3.8 2 1 1 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.7 KNZ77783.1 - 0.0044 16.6 0.4 16 5.2 0.0 4.3 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat R3H-assoc PF13902.1 KNZ77784.1 - 0.25 11.2 1.3 0.63 10.0 0.9 1.8 1 1 0 1 1 1 0 R3H-associated N-terminal domain Got1 PF04178.7 KNZ77785.1 - 1.8e-19 69.9 15.3 2.1e-19 69.7 10.6 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 KNZ77785.1 - 0.066 12.1 6.0 0.078 11.9 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) PhaG_MnhG_YufB PF03334.9 KNZ77785.1 - 7 6.7 10.0 1.3 9.0 3.2 2.1 1 1 1 2 2 2 0 Na+/H+ antiporter subunit U3_assoc_6 PF08640.6 KNZ77787.1 - 7.6e-25 86.4 3.9 6.5e-24 83.5 1.8 2.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 KNZ77787.1 - 8.6e-05 21.5 1.9 0.86 8.4 0.1 3.2 2 1 1 3 3 3 2 NRDE-2, necessary for RNA interference TPR_15 PF13429.1 KNZ77787.1 - 0.00054 19.1 5.9 0.15 11.1 0.4 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ77787.1 - 0.00087 19.7 9.8 0.24 12.1 0.1 5.1 2 2 3 5 5 5 1 Tetratricopeptide repeat DUF2087 PF09860.4 KNZ77787.1 - 0.044 13.5 0.8 3.3 7.5 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) Suf PF05843.9 KNZ77787.1 - 0.069 12.8 0.1 0.2 11.3 0.1 2.0 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) Pkinase PF00069.20 KNZ77788.1 - 1.4e-37 129.2 0.0 1.1e-35 123.0 0.0 2.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77788.1 - 1.4e-19 70.1 0.0 2.7e-19 69.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ77788.1 - 0.048 12.6 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Cyclin PF08613.6 KNZ77789.1 - 5.1e-18 65.9 0.6 8.3e-18 65.2 0.4 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KNZ77789.1 - 0.01 15.4 0.3 0.016 14.7 0.2 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Ribosomal_L11_N PF03946.9 KNZ77790.1 - 8.1e-18 63.6 0.1 1.3e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KNZ77790.1 - 4.7e-12 45.8 0.2 8.4e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain RNase_H PF00075.19 KNZ77791.1 - 6.5e-13 49.1 0.0 1.1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KNZ77791.1 - 0.028 14.1 0.0 0.099 12.4 0.0 1.9 1 0 0 1 1 1 0 Reverse transcriptase-like p450 PF00067.17 KNZ77797.1 - 4.8e-36 124.2 0.0 1.2e-35 122.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KNZ77800.1 - 1.9e-33 115.7 0.0 6.7e-23 80.9 0.0 3.0 2 1 0 2 2 2 2 Cytochrome P450 DUF1500 PF07389.7 KNZ77800.1 - 0.049 13.6 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) p450 PF00067.17 KNZ77801.1 - 1.3e-67 228.3 0.0 1.6e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1266 PF06889.6 KNZ77802.1 - 0.066 13.0 3.3 2 8.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Trp_halogenase PF04820.9 KNZ77806.1 - 4.3e-25 88.2 0.0 3.3e-18 65.5 0.0 2.4 1 1 1 2 2 2 2 Tryptophan halogenase DAO PF01266.19 KNZ77806.1 - 0.02 13.8 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Dus PF01207.12 KNZ77807.1 - 5.4e-25 87.8 0.0 1.1e-24 86.8 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF3467 PF11950.3 KNZ77808.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) Abhydrolase_2 PF02230.11 KNZ77811.1 - 1.6e-27 96.3 0.0 2.2e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KNZ77811.1 - 4.2e-06 26.5 0.0 5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ77811.1 - 0.00096 19.0 0.4 0.038 13.8 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ77811.1 - 0.01 15.0 0.0 0.78 8.9 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.15 KNZ77811.1 - 0.018 14.5 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Putative esterase YycC PF14174.1 KNZ77811.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 YycC-like protein DUF2974 PF11187.3 KNZ77811.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase_phd PF10503.4 KNZ77811.1 - 0.15 11.3 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Esterase PHB depolymerase RNase_H PF00075.19 KNZ77814.1 - 1.8e-08 34.7 0.1 2.9e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KNZ77814.1 - 0.067 12.9 0.1 6.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase-like OrfB_Zn_ribbon PF07282.6 KNZ77815.1 - 0.061 12.9 0.6 0.084 12.5 0.4 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 KNZ77815.1 - 0.095 12.6 0.3 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 KNZ77815.1 - 0.13 12.0 0.6 3.6 7.4 0.1 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-ribbon_3 PF13248.1 KNZ77815.1 - 0.14 11.3 1.4 0.27 10.4 0.9 1.5 1 1 0 1 1 1 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KNZ77815.1 - 0.15 11.8 4.3 0.31 10.8 3.0 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-IS66 PF13005.2 KNZ77815.1 - 1.1 9.2 7.3 3.3 7.7 5.1 1.8 1 1 0 1 1 1 0 zinc-finger binding domain of transposase IS66 zf-RING_3 PF14369.1 KNZ77815.1 - 7.4 6.6 8.8 0.39 10.7 0.5 2.4 2 1 1 3 3 3 0 zinc-finger SAGA-Tad1 PF12767.2 KNZ77816.1 - 0.082 12.5 9.1 0.12 12.0 6.3 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit APH PF01636.18 KNZ77818.1 - 3.7e-13 49.7 0.0 5.3e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ77818.1 - 2.9e-06 27.0 0.0 4.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KNZ77818.1 - 0.01 15.2 0.0 0.11 11.8 0.0 2.2 2 1 0 2 2 2 0 RIO1 family Pkinase PF00069.20 KNZ77818.1 - 0.032 13.3 0.0 6.8 5.7 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF1330 PF07045.6 KNZ77818.1 - 0.11 12.3 0.0 0.99 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) SSV1_ORF_D-335 PF07935.6 KNZ77820.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 ORF D-335-like protein DUF2967 PF11179.3 KNZ77822.1 - 0.0012 18.3 0.2 0.0029 17.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2967) Asp_protease_2 PF13650.1 KNZ77823.1 - 6.9e-05 23.2 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Exo_endo_phos_2 PF14529.1 KNZ77827.1 - 1.2e-06 28.0 4.2 1.5e-06 27.8 1.6 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Acetyltransf_7 PF13508.1 KNZ77828.1 - 4.3e-11 42.8 0.1 6e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ77828.1 - 1.2e-09 38.1 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KNZ77828.1 - 0.0041 16.9 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KNZ77828.1 - 0.015 15.4 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNZ77828.1 - 0.042 13.9 0.0 0.055 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KNZ77828.1 - 0.073 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Aminotran_1_2 PF00155.16 KNZ77829.1 - 2.9e-55 187.7 0.0 3.7e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KNZ77829.1 - 0.016 14.3 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.14 KNZ77829.1 - 0.13 10.9 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V tRNA-synt_His PF13393.1 KNZ77830.1 - 3.9e-43 147.6 1.8 4.7e-39 134.2 0.0 2.8 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KNZ77830.1 - 1.2e-20 73.7 0.0 2.1e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KNZ77830.1 - 4.4e-09 36.1 0.2 9.1e-09 35.1 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.2 KNZ77830.1 - 0.00012 21.3 0.2 0.0002 20.6 0.1 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.15 KNZ77830.1 - 0.03 13.5 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Cpn10 PF00166.16 KNZ77831.1 - 1.4e-22 79.3 0.0 1.6e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.19 KNZ77832.1 - 2.1e-111 372.9 4.0 2.4e-111 372.7 2.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_Helicase PF02689.9 KNZ77833.1 - 6.7e-06 24.1 0.0 7.1e-06 24.0 0.0 1.0 1 0 0 1 1 1 1 Helicase Peptidase_C9 PF01707.11 KNZ77833.1 - 0.14 11.7 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C9 PIF1 PF05970.9 KNZ77834.1 - 1.1e-34 119.9 0.0 1.3e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 KNZ77834.1 - 0.082 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KNZ77834.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Helitron_like_N PF14214.1 KNZ77835.1 - 1.8e-24 86.4 0.0 2.3e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ77835.1 - 0.0089 15.6 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) Gemini_AL1 PF00799.15 KNZ77835.1 - 0.019 14.8 0.1 0.025 14.4 0.1 1.2 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain Pertussis_S2S3 PF02918.10 KNZ77836.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain Ribosomal_L24e PF01246.15 KNZ77837.1 - 9.7e-31 105.4 0.4 9.7e-31 105.4 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e MinC_C PF03775.11 KNZ77837.1 - 0.17 11.5 1.0 7.6 6.2 0.5 2.2 1 1 1 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain TerB-C PF15615.1 KNZ77837.1 - 1.1 9.4 3.7 1.5 9.0 2.5 1.1 1 0 0 1 1 1 0 TerB-C domain Mo25 PF08569.6 KNZ77838.1 - 3.8e-114 381.2 12.2 4.2e-114 381.0 8.5 1.0 1 0 0 1 1 1 1 Mo25-like EthD PF07110.6 KNZ77839.1 - 0.1 13.5 0.0 0.18 12.7 0.0 1.6 1 0 0 1 1 1 0 EthD domain Pkinase PF00069.20 KNZ77840.1 - 7e-12 45.0 0.0 8.9e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KNZ77840.1 - 2e-06 27.7 1.1 5.5e-05 23.0 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KNZ77840.1 - 9.5e-06 25.0 0.1 1.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KNZ77840.1 - 1.3e-05 24.3 0.1 1.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KNZ77840.1 - 1.5e-05 24.6 0.0 0.00034 20.2 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 KNZ77840.1 - 2.2e-05 23.6 0.0 2.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Saccharop_dh_N PF04455.7 KNZ77840.1 - 0.00014 21.9 0.5 0.0025 17.8 0.0 2.6 3 0 0 3 3 3 1 LOR/SDH bifunctional enzyme conserved region PIP49_C PF12260.3 KNZ77840.1 - 0.027 13.8 0.1 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF221 PF02714.10 KNZ77841.1 - 6e-87 291.5 25.2 2.5e-85 286.2 17.5 2.4 1 1 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KNZ77841.1 - 1.3e-34 119.0 2.3 1.3e-34 119.0 1.6 2.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KNZ77841.1 - 5.6e-12 46.0 0.0 1.1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) EF-hand_7 PF13499.1 KNZ77843.1 - 1.1e-12 47.8 0.0 1.9e-07 31.1 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KNZ77843.1 - 1.1e-11 43.5 0.2 6.1e-05 22.5 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KNZ77843.1 - 8.5e-10 37.2 0.0 0.00046 19.3 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 KNZ77843.1 - 5.2e-06 26.2 0.0 0.0081 16.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KNZ77843.1 - 9.1e-06 25.2 0.0 0.00063 19.2 0.0 3.0 2 1 1 3 3 3 1 EF-hand domain pair UPF0154 PF03672.8 KNZ77843.1 - 0.05 13.2 0.0 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) SapB_1 PF05184.10 KNZ77843.1 - 0.13 12.0 0.0 17 5.3 0.0 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 MFS_1 PF07690.11 KNZ77844.1 - 1.7e-46 158.5 47.8 6.7e-33 113.8 7.1 3.5 2 1 2 4 4 4 3 Major Facilitator Superfamily ESSS PF10183.4 KNZ77844.1 - 0.053 13.9 1.3 5 7.5 0.0 3.8 2 1 1 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) EphA2_TM PF14575.1 KNZ77844.1 - 1.3 9.4 0.0 1.3 9.4 0.0 3.1 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain RF-1 PF00472.15 KNZ77845.1 - 8.1e-37 125.5 3.5 1.4e-36 124.7 2.4 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 KNZ77845.1 - 2.2e-31 107.9 0.0 4.5e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 PCRF domain PIF1 PF05970.9 KNZ77847.1 - 2.5e-52 178.0 0.0 3.1e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ77847.1 - 0.00065 19.3 0.0 0.0012 18.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KNZ77847.1 - 0.017 14.6 0.1 0.041 13.3 0.1 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KNZ77847.1 - 0.023 14.5 0.0 0.054 13.3 0.0 1.6 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KNZ77847.1 - 0.096 12.8 0.1 0.58 10.3 0.1 2.3 1 1 0 1 1 1 0 RNA helicase PIF1 PF05970.9 KNZ77848.1 - 1.4e-16 60.4 0.0 1.7e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase p450 PF00067.17 KNZ77849.1 - 5.5e-46 157.0 0.1 7.1e-46 156.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.17 KNZ77850.1 - 1.1e-180 600.9 0.3 1.2e-180 600.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KNZ77850.1 - 0.0024 16.6 0.0 0.0057 15.4 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KNZ77850.1 - 0.015 14.5 0.0 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) SPX PF03105.14 KNZ77851.1 - 3.3e-19 69.7 1.6 2.6e-08 34.0 1.0 2.2 2 0 0 2 2 2 2 SPX domain CMAS PF02353.15 KNZ77852.1 - 4.6e-28 98.0 0.0 4.3e-26 91.6 0.0 2.0 1 1 1 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 KNZ77852.1 - 1.8e-06 28.3 0.0 3.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ77852.1 - 0.0036 17.7 0.0 0.0056 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ77852.1 - 0.0037 17.0 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ77852.1 - 0.0088 16.6 0.0 0.02 15.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ77852.1 - 0.016 15.5 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ77852.1 - 0.1 12.6 0.0 0.44 10.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain cEGF PF12662.2 KNZ77854.1 - 0.045 13.4 1.3 0.045 13.4 0.9 5.4 4 1 1 5 5 5 0 Complement Clr-like EGF-like CBM_14 PF01607.19 KNZ77854.1 - 0.054 13.4 0.2 0.054 13.4 0.2 5.0 3 1 2 5 5 5 0 Chitin binding Peritrophin-A domain Myosin_head PF00063.16 KNZ77855.1 - 3.8e-224 745.7 0.7 3.6e-222 739.2 0.0 3.7 3 1 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KNZ77855.1 - 2.4e-39 134.7 285.3 1.3e-25 89.3 76.3 5.5 3 2 1 4 4 4 4 Myosin tail Myosin_N PF02736.14 KNZ77855.1 - 1.2e-08 34.4 0.5 1.2e-08 34.4 0.3 1.9 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 KNZ77855.1 - 0.027 14.5 0.0 0.027 14.5 0.0 4.1 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 KNZ77855.1 - 0.052 13.3 0.0 0.27 11.0 0.0 2.3 1 0 0 1 1 1 0 Part of AAA domain DUF2611 PF11022.3 KNZ77856.1 - 3.6e-06 26.9 1.0 3.9e-06 26.8 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) EcoR124_C PF12008.3 KNZ77856.1 - 0.051 12.7 1.1 0.052 12.7 0.8 1.0 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal An_peroxidase PF03098.10 KNZ77857.1 - 8.6e-76 255.4 0.0 1.5e-73 248.0 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase Aconitase_C PF00694.14 KNZ77862.1 - 1.8e-18 66.9 0.0 1.8e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Aconitase C-terminal domain G2F PF07474.7 KNZ77862.1 - 0.05 12.9 0.0 0.058 12.7 0.0 1.1 1 0 0 1 1 1 0 G2F domain IPK PF03770.11 KNZ77863.1 - 6.2e-31 107.5 0.0 8.9e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase E_Pc_C PF06752.7 KNZ77864.1 - 0.56 9.6 6.1 0.62 9.5 4.2 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Pyr_redox_3 PF13738.1 KNZ77865.1 - 5.8e-25 88.5 0.0 1.3e-24 87.3 0.0 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KNZ77865.1 - 4.9e-15 54.7 0.0 7.4e-15 54.1 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KNZ77865.1 - 1.2e-09 37.9 1.2 5.3e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KNZ77865.1 - 2.9e-09 37.0 0.0 6.5e-05 22.9 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KNZ77865.1 - 6.6e-09 35.1 0.0 1.8e-06 27.1 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KNZ77865.1 - 2.8e-06 26.5 0.0 0.0079 15.1 0.0 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KNZ77865.1 - 0.00025 21.3 0.3 1.2 9.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KNZ77865.1 - 0.00047 19.3 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KNZ77865.1 - 0.0036 17.0 6.2 0.03 14.0 0.1 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KNZ77865.1 - 0.0052 15.7 0.1 0.016 14.1 0.0 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KNZ77865.1 - 0.018 14.1 0.0 0.018 14.1 0.0 2.1 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.17 KNZ77865.1 - 0.047 12.5 0.0 3.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KNZ77865.1 - 0.061 11.7 0.9 0.14 10.5 0.1 2.0 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.1 KNZ77865.1 - 0.095 12.9 0.0 13 6.1 0.0 2.5 3 0 0 3 3 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 KNZ77865.1 - 0.1 11.3 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain GvpH PF05455.6 KNZ77866.1 - 0.11 12.0 0.2 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 GvpH Pyr_redox_3 PF13738.1 KNZ77867.1 - 1.9e-25 90.1 0.0 4.1e-25 89.0 0.0 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KNZ77867.1 - 4.8e-14 51.4 0.0 8.2e-14 50.6 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KNZ77867.1 - 6.8e-10 39.1 0.0 3.3e-06 27.1 0.0 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ77867.1 - 8e-10 38.6 0.2 9.2e-09 35.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KNZ77867.1 - 3.8e-09 35.9 0.0 1.1e-06 27.8 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KNZ77867.1 - 2.2e-06 26.8 0.0 0.0065 15.4 0.0 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KNZ77867.1 - 8.1e-05 22.9 0.2 0.73 10.2 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNZ77867.1 - 0.0011 18.8 4.5 0.021 14.6 0.0 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 KNZ77867.1 - 0.0013 17.9 0.0 0.003 16.7 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KNZ77867.1 - 0.0018 18.4 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KNZ77867.1 - 0.0071 15.2 0.0 0.021 13.7 0.0 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KNZ77867.1 - 0.011 14.8 0.0 0.011 14.8 0.0 2.0 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.17 KNZ77867.1 - 0.016 14.1 0.0 1.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KNZ77867.1 - 0.049 12.0 0.5 0.14 10.6 0.0 2.0 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.19 KNZ77867.1 - 0.053 12.3 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Herpes_gE PF02480.11 KNZ77868.1 - 0.0034 15.7 0.0 0.0054 15.0 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 KNZ77868.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Rifin_STEVOR PF02009.11 KNZ77868.1 - 0.089 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family MLANA PF14991.1 KNZ77868.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A DUF4556 PF15094.1 KNZ77869.1 - 0.0063 16.0 0.6 0.0084 15.6 0.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4556) Lin-8 PF03353.10 KNZ77869.1 - 0.4 9.9 2.0 0.66 9.1 1.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Asp_protease_2 PF13650.1 KNZ77871.1 - 0.00062 20.2 0.0 0.00079 19.8 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ77871.1 - 0.0019 17.7 0.0 0.0023 17.4 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease MgtE PF01769.11 KNZ77875.1 - 3e-17 63.1 18.0 3.5e-07 30.5 0.3 4.0 2 2 1 3 3 3 3 Divalent cation transporter EssA PF10661.4 KNZ77875.1 - 0.22 11.1 0.1 9.1 5.9 0.0 2.2 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA FA_desaturase PF00487.19 KNZ77875.1 - 1.6 8.1 5.5 0.65 9.3 0.1 2.7 2 1 0 2 2 2 0 Fatty acid desaturase Ada3 PF10198.4 KNZ77876.1 - 2.5e-24 85.5 0.2 2.5e-24 85.5 0.1 2.4 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 CR6_interact PF10147.4 KNZ77876.1 - 0.0034 16.7 1.0 0.0034 16.7 0.7 3.3 3 1 0 3 3 3 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Acetyltransf_11 PF13720.1 KNZ77876.1 - 0.48 10.6 2.3 0.47 10.7 0.2 2.0 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 RNA_polI_A34 PF08208.6 KNZ77877.1 - 1e-09 38.3 6.5 1e-09 38.3 4.5 1.7 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 zf-RING_2 PF13639.1 KNZ77878.1 - 6.7e-06 25.8 5.3 6.7e-06 25.8 3.7 1.8 2 0 0 2 2 1 1 Ring finger domain SWIM PF04434.12 KNZ77878.1 - 0.00047 19.5 0.5 0.00094 18.5 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger PHD PF00628.24 KNZ77878.1 - 0.00055 19.5 6.1 0.001 18.7 4.2 1.5 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.3 KNZ77878.1 - 0.0037 17.1 4.3 0.0037 17.1 3.0 2.1 3 0 0 3 3 3 1 FANCL C-terminal domain zf-rbx1 PF12678.2 KNZ77878.1 - 0.0066 16.5 1.6 0.0066 16.5 1.1 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger zf-PHD-like PF15446.1 KNZ77878.1 - 0.011 15.0 3.7 0.019 14.2 2.5 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 KNZ77878.1 - 0.032 13.5 1.7 0.065 12.5 1.2 1.6 1 0 0 1 1 1 0 PHD-finger zf-UDP PF14569.1 KNZ77878.1 - 0.22 11.2 2.1 0.31 10.8 0.7 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.1 KNZ77878.1 - 0.34 10.9 9.5 0.098 12.7 4.3 1.9 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 KNZ77878.1 - 1.2 8.9 8.6 0.071 12.8 2.0 1.9 2 1 0 2 2 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.1 KNZ77878.1 - 1.3 8.7 9.8 0.072 12.7 2.8 2.0 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ77878.1 - 5.6 6.7 10.6 1.4 8.6 4.5 2.2 2 1 0 2 2 2 0 zinc-RING finger domain RINGv PF12906.2 KNZ77878.1 - 5.6 7.0 15.3 0.062 13.3 5.0 1.9 2 0 0 2 2 2 0 RING-variant domain zf-MIZ PF02891.15 KNZ77878.1 - 9.4 5.8 12.2 9.9 5.7 1.5 3.3 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger OTT_1508_deam PF14441.1 KNZ77879.1 - 3.2e-07 30.2 0.0 5.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase TMF_TATA_bd PF12325.3 KNZ77880.1 - 0.0083 15.8 3.9 0.0083 15.8 2.7 2.3 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 KNZ77880.1 - 0.094 12.5 20.7 0.17 11.7 12.0 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 KNZ77880.1 - 0.12 11.3 15.6 0.16 10.9 10.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 KNZ77880.1 - 0.26 11.6 15.4 0.5 10.7 4.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF972) FUSC PF04632.7 KNZ77880.1 - 0.67 8.3 3.8 0.81 8.0 2.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family GAS PF13851.1 KNZ77880.1 - 0.77 8.9 19.4 1.3 8.2 4.7 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Nsp1_C PF05064.8 KNZ77880.1 - 0.83 9.3 9.8 0.29 10.7 1.0 2.3 1 1 0 2 2 2 0 Nsp1-like C-terminal region PIN_4 PF13638.1 KNZ77880.1 - 2.1 8.4 9.8 2.6 8.1 6.2 1.6 1 1 0 1 1 1 0 PIN domain Alpha-mann_mid PF09261.6 KNZ77880.1 - 2.5 8.3 4.5 1.9 8.7 1.1 2.0 1 1 1 2 2 2 0 Alpha mannosidase, middle domain DUF2229 PF09989.4 KNZ77880.1 - 3 7.2 8.9 0.76 9.1 2.3 1.9 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Bap31 PF05529.7 KNZ77880.1 - 3.2 7.1 13.0 24 4.3 9.0 2.0 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Fib_alpha PF08702.5 KNZ77880.1 - 3.7 7.6 7.6 6.4 6.8 5.2 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.10 KNZ77880.1 - 4.1 6.5 12.0 4.8 6.2 8.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HrpA_pilin PF09589.5 KNZ77880.1 - 4.6 7.7 8.0 43 4.5 5.5 2.2 1 1 0 1 1 1 0 HrpA pilus formation protein Striatin PF08232.7 KNZ77880.1 - 6.5 7.0 16.5 1.7 8.9 2.5 2.1 1 1 1 2 2 2 0 Striatin family DUF2654 PF10849.3 KNZ77880.1 - 7.1 6.4 10.0 0.36 10.6 1.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2654) TPR_11 PF13414.1 KNZ77881.1 - 1.9e-21 75.4 16.8 2.4e-15 55.9 6.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KNZ77881.1 - 1.3e-15 56.2 11.6 5.3e-08 32.1 0.9 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ77881.1 - 8.3e-14 50.3 12.4 3.9e-06 26.3 1.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ77881.1 - 4.4e-09 36.7 25.1 4.4e-06 27.2 7.0 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ77881.1 - 4e-08 33.0 21.1 4.8e-07 29.6 5.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ77881.1 - 1.3e-06 28.1 2.4 0.048 13.8 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ77881.1 - 4e-06 26.9 12.2 0.0061 17.0 2.8 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ77881.1 - 5.1e-06 26.7 13.1 4.3e-05 23.7 7.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ77881.1 - 8.7e-06 25.1 10.2 0.019 14.7 0.3 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ77881.1 - 0.00026 20.7 3.5 0.00026 20.7 2.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ77881.1 - 0.00051 20.3 12.3 0.12 12.8 0.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ77881.1 - 0.0008 19.0 8.6 0.022 14.5 0.4 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ77881.1 - 0.00082 19.2 8.1 0.027 14.4 1.5 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Coatomer_E PF04733.9 KNZ77881.1 - 0.0025 17.0 3.5 0.0046 16.1 2.4 1.4 1 0 0 1 1 1 1 Coatomer epsilon subunit Glyco_hydro_42M PF08532.5 KNZ77881.1 - 0.0064 15.6 1.1 13 4.8 0.0 4.5 5 0 0 5 5 5 0 Beta-galactosidase trimerisation domain DUF3856 PF12968.2 KNZ77881.1 - 0.015 15.1 3.8 0.043 13.6 2.6 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) ADH_zinc_N PF00107.21 KNZ77881.1 - 0.1 12.1 0.2 5.8 6.4 0.0 3.2 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Apc3 PF12895.2 KNZ77881.1 - 0.48 10.5 9.5 0.27 11.4 3.9 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Mak10 PF04112.8 KNZ77882.1 - 7.9e-31 106.5 0.0 1.9e-30 105.2 0.0 1.7 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase tRNA-synt_1b PF00579.20 KNZ77883.1 - 1.8e-72 243.9 0.0 2.4e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) p450 PF00067.17 KNZ77886.1 - 9.2e-08 31.0 0.0 0.00011 20.8 0.0 2.5 3 0 0 3 3 3 2 Cytochrome P450 MRP-S33 PF08293.6 KNZ77887.1 - 6.9e-19 67.6 1.3 8.8e-19 67.2 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Helicase_C PF00271.26 KNZ77888.1 - 7.7e-10 38.5 0.0 1.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.3 KNZ77888.1 - 0.00033 20.0 0.3 0.00076 18.8 0.2 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Phage_int_SAM_1 PF02899.12 KNZ77888.1 - 0.19 11.9 3.2 1.9 8.6 0.1 3.2 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain MFS_1 PF07690.11 KNZ77892.1 - 1.8e-32 112.4 39.4 1.3e-31 109.6 25.7 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ77892.1 - 8.1e-09 34.5 13.2 8.1e-09 34.5 9.1 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Lipase_3 PF01764.20 KNZ77893.1 - 5e-08 32.6 0.0 2.9e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KNZ77893.1 - 0.051 13.3 0.1 0.14 11.9 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Carn_acyltransf PF00755.15 KNZ77895.1 - 5.3e-150 500.3 0.0 1.9e-74 250.8 0.0 2.0 1 1 1 2 2 2 2 Choline/Carnitine o-acyltransferase F-box-like PF12937.2 KNZ77896.1 - 0.016 14.8 0.3 0.11 12.2 0.0 2.4 3 0 0 3 3 3 0 F-box-like 7TMR-DISM_7TM PF07695.6 KNZ77898.1 - 0.21 11.2 13.7 0.042 13.5 5.5 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling BTB PF00651.26 KNZ77899.1 - 0.0079 16.1 0.0 0.022 14.7 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain DUF1649 PF07855.7 KNZ77901.1 - 3.9e-18 65.6 1.0 1e-09 38.2 0.1 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF1649) OPA3 PF07047.7 KNZ77902.1 - 1.8e-30 105.4 0.2 2.7e-30 104.8 0.2 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF1465 PF07323.7 KNZ77902.1 - 0.042 13.4 0.3 0.087 12.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Phage_GP20 PF06810.6 KNZ77902.1 - 0.15 11.5 1.3 0.28 10.6 0.9 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 IncA PF04156.9 KNZ77902.1 - 0.43 10.1 3.7 0.39 10.2 1.9 1.3 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 KNZ77902.1 - 0.47 10.3 5.4 0.17 11.8 1.9 1.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.4 KNZ77902.1 - 0.91 9.6 3.6 3.9 7.6 0.1 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cellulase PF00150.13 KNZ77903.1 - 3e-13 49.5 0.0 5.5e-07 29.0 0.0 2.8 3 0 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 KNZ77903.1 - 0.02 14.2 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Glyco_hydro_7 PF00840.15 KNZ77904.1 - 1.5e-218 725.4 20.9 2.3e-218 724.8 14.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 KNZ77904.1 - 5.2e-12 45.2 13.2 5.2e-12 45.2 9.2 4.1 5 1 0 5 5 5 1 Fungal cellulose binding domain Aldolase_II PF00596.16 KNZ77905.1 - 3.9e-36 124.3 0.1 1.3e-35 122.6 0.0 1.7 1 1 1 2 2 2 1 Class II Aldolase and Adducin N-terminal domain rve PF00665.21 KNZ77906.1 - 0.0002 21.4 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF1719 PF08224.6 KNZ77906.1 - 0.02 13.9 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) eIF2A PF08662.6 KNZ77907.1 - 2.3e-76 255.8 0.0 1.4e-75 253.2 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KNZ77907.1 - 0.027 14.3 0.3 6.1 6.8 0.1 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat Proteasome_A_N PF10584.4 KNZ77907.1 - 0.12 11.6 1.0 55 3.2 0.0 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature CDV3 PF15359.1 KNZ77907.1 - 1.6 8.8 10.2 0.085 12.9 2.0 2.6 3 1 0 3 3 3 0 Carnitine deficiency-associated protein 3 adh_short PF00106.20 KNZ77909.1 - 2.5e-20 73.0 0.1 6.4e-20 71.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ77909.1 - 5.9e-14 52.4 0.1 4.5e-13 49.5 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KNZ77909.1 - 0.00088 19.3 0.2 0.0014 18.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KNZ77909.1 - 0.002 18.1 0.1 0.0025 17.8 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KNZ77909.1 - 0.0022 17.6 1.7 0.012 15.3 0.0 2.6 2 1 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.14 KNZ77909.1 - 0.009 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 KNZ77909.1 - 0.016 14.8 0.2 0.023 14.3 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KNZ77909.1 - 0.066 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KNZ77909.1 - 0.085 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding RhoGEF PF00621.15 KNZ77910.1 - 4.1e-39 134.3 1.6 7.1e-39 133.5 1.1 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 KNZ77910.1 - 7.6e-21 73.2 0.5 6.4e-13 47.8 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KNZ77910.1 - 1.3e-19 69.5 1.7 1.3e-09 37.5 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.2 KNZ77910.1 - 1.9e-16 59.6 0.0 4.3e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.12 KNZ77910.1 - 8.1e-11 41.2 0.0 5.6e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PH PF00169.24 KNZ77910.1 - 0.011 15.9 0.0 0.034 14.3 0.0 1.9 1 0 0 1 1 1 0 PH domain WH2 PF02205.15 KNZ77910.1 - 0.012 15.2 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 WH2 motif F-box-like PF12937.2 KNZ77911.1 - 1.8e-09 37.1 1.3 5.1e-09 35.7 0.9 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KNZ77911.1 - 0.0065 16.0 0.2 0.046 13.3 0.2 2.5 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KNZ77912.1 - 7.2e-06 25.6 2.8 2.6e-05 23.8 2.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ77912.1 - 0.6 9.8 4.5 0.98 9.1 0.1 3.2 3 0 0 3 3 3 0 F-box domain Pkinase PF00069.20 KNZ77914.1 - 5.2e-49 166.7 0.0 7.8e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77914.1 - 7.3e-22 77.6 0.0 1.5e-21 76.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KNZ77914.1 - 0.023 13.5 0.1 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KNZ77914.1 - 0.071 12.4 0.2 2.6 7.3 0.1 2.5 1 1 0 1 1 1 0 RIO1 family Cyclase PF04199.8 KNZ77915.1 - 3.5e-15 56.1 0.0 5.1e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Shugoshin_C PF07557.6 KNZ77916.1 - 9.4e-11 40.9 5.1 1e-10 40.8 1.4 2.8 2 0 0 2 2 2 1 Shugoshin C terminus Shugoshin_N PF07558.6 KNZ77916.1 - 1.4e-06 27.9 3.0 2.9e-06 26.8 2.1 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DUF3584 PF12128.3 KNZ77916.1 - 0.076 10.3 2.5 0.11 9.7 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PP2C PF00481.16 KNZ77918.1 - 1.4e-17 63.9 0.0 1.4e-15 57.3 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KNZ77918.1 - 0.00084 19.0 0.0 0.011 15.4 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) MFS_1 PF07690.11 KNZ77919.1 - 4.6e-33 114.3 48.8 4.6e-33 114.3 33.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3154 PF11351.3 KNZ77919.1 - 0.043 13.5 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) adh_short PF00106.20 KNZ77920.1 - 2.9e-15 56.5 0.8 4.9e-15 55.8 0.0 1.7 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ77920.1 - 2.7e-05 24.0 0.0 4.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ77920.1 - 0.00016 21.4 0.1 0.00037 20.2 0.0 1.6 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KNZ77920.1 - 0.0035 17.0 0.2 0.007 16.0 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 KNZ77920.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family VitK2_biosynth PF02621.9 KNZ77920.1 - 0.04 13.1 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 Menaquinone biosynthesis YjeF_N PF03853.10 KNZ77920.1 - 0.059 12.9 0.1 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus 2-Hacid_dh_C PF02826.14 KNZ77920.1 - 0.097 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4519 PF15012.1 KNZ77921.1 - 0.62 10.0 3.1 1.4 8.9 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Terpene_synth_C PF03936.11 KNZ77923.1 - 0.00013 21.3 0.1 0.00025 20.3 0.0 1.5 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain DUF2975 PF11188.3 KNZ77923.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) SR-25 PF10500.4 KNZ77924.1 - 0.037 13.5 10.3 0.057 12.8 7.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LRR_6 PF13516.1 KNZ77924.1 - 0.051 13.6 0.1 33 4.9 0.0 4.9 6 0 0 6 6 6 0 Leucine Rich repeat HSP70 PF00012.15 KNZ77924.1 - 6.4 4.5 8.4 9.7 3.9 5.8 1.1 1 0 0 1 1 1 0 Hsp70 protein MFS_1 PF07690.11 KNZ77925.1 - 1.6e-30 106.0 35.5 1.6e-30 106.0 24.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3353 PF11833.3 KNZ77925.1 - 2 7.8 16.8 0.43 10.0 5.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) Piwi PF02171.12 KNZ77926.1 - 1.1e-76 257.7 0.0 1.5e-76 257.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KNZ77926.1 - 6.8e-16 57.3 0.1 1.4e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KNZ77926.1 - 9.9e-09 34.6 0.0 2.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 PAZ domain RdRP_4 PF02123.11 KNZ77926.1 - 0.11 11.1 0.1 0.77 8.4 0.0 2.1 2 0 0 2 2 2 0 Viral RNA-directed RNA-polymerase DUF4455 PF14643.1 KNZ77926.1 - 0.19 10.2 0.1 0.3 9.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF4181 PF13789.1 KNZ77927.1 - 0.98 9.3 5.0 0.64 9.9 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4181) DUF2304 PF10066.4 KNZ77927.1 - 2.5 7.9 8.2 0.36 10.6 1.9 2.2 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) C2 PF00168.25 KNZ77928.1 - 1.5e-15 56.7 0.1 2.7e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 C2 domain Peptidase_C48 PF02902.14 KNZ77929.1 - 0.00012 21.7 2.6 0.00018 21.2 1.8 1.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain C2 PF00168.25 KNZ77930.1 - 6.2e-17 61.2 0.1 1.1e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain Glyco_hydro_31 PF01055.21 KNZ77932.1 - 2.2e-161 537.5 1.1 2.8e-161 537.2 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KNZ77932.1 - 4e-11 42.6 0.4 1.4e-10 40.8 0.3 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like F-box-like PF12937.2 KNZ77933.1 - 1e-06 28.3 2.5 1e-06 28.3 0.2 2.2 2 0 0 2 2 2 1 F-box-like Aldo_ket_red PF00248.16 KNZ77934.1 - 4e-70 235.8 0.0 4.8e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DNA_ligase_A_M PF01068.16 KNZ77935.1 - 0.0049 16.2 0.1 0.006 15.9 0.0 1.0 1 0 0 1 1 1 1 ATP dependent DNA ligase domain Auxin_BP PF02041.11 KNZ77935.1 - 0.039 13.3 0.1 0.045 13.2 0.1 1.3 1 0 0 1 1 1 0 Auxin binding protein DUF4252 PF14060.1 KNZ77935.1 - 0.04 13.4 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Ion_trans PF00520.26 KNZ77936.1 - 3.3e-16 59.1 15.9 3.3e-16 59.1 11.0 1.4 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 KNZ77936.1 - 5.8e-10 38.7 8.9 5.8e-10 38.7 6.2 3.1 2 2 1 3 3 3 1 Ion channel Lig_chan PF00060.21 KNZ77936.1 - 0.011 15.4 0.8 0.011 15.4 0.6 1.9 2 0 0 2 2 2 0 Ligand-gated ion channel GET2 PF08690.5 KNZ77936.1 - 0.88 8.7 2.6 1.4 8.0 1.8 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 BBE PF08031.7 KNZ77937.1 - 3.9e-09 36.2 0.8 1.2e-08 34.6 0.6 1.9 1 1 0 1 1 1 1 Berberine and berberine like Filament PF00038.16 KNZ77938.1 - 0.0022 17.5 4.1 0.0029 17.1 2.8 1.2 1 0 0 1 1 1 1 Intermediate filament protein NPR2 PF06218.6 KNZ77938.1 - 0.0097 14.6 0.3 0.013 14.2 0.2 1.1 1 0 0 1 1 1 1 Nitrogen permease regulator 2 DivIC PF04977.10 KNZ77938.1 - 0.027 13.9 9.3 0.41 10.1 2.3 2.3 1 1 1 2 2 2 0 Septum formation initiator FlaC_arch PF05377.6 KNZ77938.1 - 0.27 11.1 1.8 4.6 7.2 0.2 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) HALZ PF02183.13 KNZ77938.1 - 0.27 10.9 2.4 7.5 6.3 0.1 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Bap31 PF05529.7 KNZ77938.1 - 0.76 9.2 3.0 1 8.7 2.1 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like CENP-H PF05837.7 KNZ77938.1 - 0.84 9.8 6.3 0.86 9.8 3.4 1.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF972 PF06156.8 KNZ77938.1 - 0.86 9.9 6.4 8.8 6.7 4.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF904 PF06005.7 KNZ77938.1 - 3.9 7.8 10.7 2e+02 2.3 7.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) AAA PF00004.24 KNZ77939.1 - 5.9e-21 75.0 0.0 7.1e-12 45.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 KNZ77939.1 - 1.7e-20 73.4 0.2 4.6e-20 72.0 0.3 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA_17 PF13207.1 KNZ77939.1 - 0.00077 20.2 0.3 0.0031 18.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KNZ77939.1 - 0.00097 18.7 0.0 0.004 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KNZ77939.1 - 0.0012 18.3 0.0 0.0035 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KNZ77939.1 - 0.0016 18.1 0.2 0.004 16.8 0.0 1.7 2 0 0 2 2 1 1 Part of AAA domain KaiC PF06745.8 KNZ77939.1 - 0.019 14.1 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 KaiC RuvB_N PF05496.7 KNZ77939.1 - 0.021 13.8 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KNZ77939.1 - 0.025 14.5 0.0 0.067 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.1 KNZ77939.1 - 0.041 13.4 0.4 0.092 12.3 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KNZ77939.1 - 0.06 13.4 0.1 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KNZ77939.1 - 0.087 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 KNZ77939.1 - 0.2 11.5 2.0 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain FAD_binding_4 PF01565.18 KNZ77942.1 - 1.8e-32 111.6 2.7 3.8e-32 110.6 1.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KNZ77942.1 - 4.1e-09 36.2 0.3 1.1e-08 34.7 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like Tropomyosin PF00261.15 KNZ77943.1 - 0.0083 15.2 3.9 0.012 14.6 2.7 1.1 1 0 0 1 1 1 1 Tropomyosin SF-assemblin PF06705.6 KNZ77943.1 - 0.0087 15.2 0.2 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 SF-assemblin/beta giardin phiKZ_IP PF12699.2 KNZ77943.1 - 0.013 14.4 0.1 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins RmuC PF02646.11 KNZ77943.1 - 0.06 12.1 0.4 0.089 11.6 0.3 1.2 1 0 0 1 1 1 0 RmuC family Med9 PF07544.8 KNZ77943.1 - 0.12 12.1 1.2 0.23 11.2 0.2 1.9 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Abhydrolase_6 PF12697.2 KNZ77944.1 - 3.6e-13 49.9 0.0 6.3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ77944.1 - 0.0004 20.1 0.0 0.0007 19.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Myb_DNA-binding PF00249.26 KNZ77945.1 - 3.8e-17 62.0 0.1 4.8e-09 36.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KNZ77945.1 - 7.1e-12 45.2 0.0 0.00012 22.1 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Prefoldin PF02996.12 KNZ77946.1 - 5.5e-28 97.0 3.4 3.4e-25 88.0 2.4 2.3 1 1 0 1 1 1 1 Prefoldin subunit PilJ PF13675.1 KNZ77946.1 - 0.021 15.1 2.6 1.6 9.1 0.3 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term CobN-Mg_chel PF02514.11 KNZ77946.1 - 0.077 10.3 2.6 0.085 10.2 1.8 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase NPV_P10 PF05531.7 KNZ77946.1 - 0.12 12.6 4.5 4.7 7.5 0.0 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein BCAS3 PF12490.3 KNZ77946.1 - 0.14 11.4 1.7 0.17 11.1 0.9 1.4 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 3 HrpB7 PF09486.5 KNZ77946.1 - 0.76 9.6 6.7 2.7 7.9 0.5 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DivIC PF04977.10 KNZ77946.1 - 1.2 8.6 7.8 5.1 6.6 0.0 3.3 2 1 0 3 3 3 0 Septum formation initiator Lebercilin PF15619.1 KNZ77946.1 - 3.1 7.1 10.7 3.3 7.0 1.1 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease RRM_1 PF00076.17 KNZ77947.1 - 1.8e-71 235.7 0.1 9.3e-20 70.0 0.0 5.7 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ77947.1 - 1.3e-58 194.9 0.0 8.7e-15 54.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ77947.1 - 8.2e-31 105.6 0.0 4.6e-09 36.0 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 KNZ77947.1 - 0.0037 17.2 0.0 13 5.8 0.0 3.9 4 0 0 4 4 4 1 RNA recognition motif 2 RRM_3 PF08777.6 KNZ77947.1 - 0.0072 16.1 0.4 2.9 7.7 0.0 4.7 5 2 0 5 5 5 1 RNA binding motif DUF3343 PF11823.3 KNZ77947.1 - 0.082 12.1 0.0 0.21 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) DUF2960 PF11173.3 KNZ77947.1 - 0.11 12.7 0.1 24 5.3 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2960) SNF2_N PF00176.18 KNZ77948.1 - 7.5e-43 146.4 0.0 1.6e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 KNZ77948.1 - 4.6e-06 26.3 13.6 8.2e-06 25.5 9.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KNZ77948.1 - 5e-06 26.0 11.4 8.7e-06 25.3 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ77948.1 - 8.2e-06 25.7 12.9 1.5e-05 24.9 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNZ77948.1 - 1.1e-05 25.0 12.6 1.9e-05 24.2 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ77948.1 - 0.00048 19.8 15.1 0.00083 19.0 10.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KNZ77948.1 - 0.0017 18.3 7.1 0.0045 17.0 4.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KNZ77948.1 - 0.048 13.4 4.9 0.12 12.2 3.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KNZ77948.1 - 0.6 9.6 7.6 1.6 8.3 5.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 KNZ77948.1 - 3.3 7.6 11.1 6.4 6.7 7.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Herpes_gE PF02480.11 KNZ77952.1 - 0.0075 14.5 0.0 0.01 14.1 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 KNZ77952.1 - 0.014 14.2 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF1049 PF06305.6 KNZ77952.1 - 0.015 14.7 1.2 0.049 13.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TMEM154 PF15102.1 KNZ77952.1 - 0.032 13.9 0.1 0.05 13.3 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 KNZ77952.1 - 0.057 13.8 0.0 0.096 13.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1517 PF07466.6 KNZ77952.1 - 0.077 11.9 1.3 0.12 11.3 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Syndecan PF01034.15 KNZ77952.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Peptidase_M56 PF05569.6 KNZ77952.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 STE3 PF02076.10 KNZ77953.1 - 9.8e-55 185.6 15.3 1.4e-54 185.1 10.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor BPD_transp_2 PF02653.11 KNZ77953.1 - 2.3 7.1 12.7 0.57 9.0 1.9 2.3 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component STE3 PF02076.10 KNZ77954.1 - 1.3e-91 306.5 9.3 1.6e-91 306.2 6.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor CBF PF03914.12 KNZ77955.1 - 1.4e-39 135.1 2.4 1.4e-39 135.1 1.7 2.0 2 1 0 2 2 2 1 CBF/Mak21 family STE3 PF02076.10 KNZ77956.1 - 3.3e-86 288.8 11.6 3.9e-86 288.6 8.1 1.0 1 0 0 1 1 1 1 Pheromone A receptor PEMT PF04191.8 KNZ77957.1 - 7.3e-15 54.9 0.5 7.7e-14 51.6 0.1 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 KNZ77957.1 - 3.2e-12 46.4 0.1 4e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 KNZ77957.1 - 1.4e-07 30.4 0.5 1.9e-07 29.9 0.4 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KNZ77957.1 - 0.0053 16.0 0.0 0.0072 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) HTH_39 PF14090.1 KNZ77957.1 - 0.09 12.2 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain PEMT PF04191.8 KNZ77958.1 - 1.1e-06 28.6 2.1 0.00016 21.7 0.4 2.1 1 1 1 2 2 2 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KNZ77958.1 - 0.0038 15.8 0.1 0.0045 15.5 0.1 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 KNZ77958.1 - 0.0089 16.2 1.0 0.057 13.6 0.2 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KNZ77959.1 - 4.1e-13 49.3 0.6 2e-11 43.9 0.6 2.0 1 1 1 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 KNZ77959.1 - 4.1e-12 46.1 0.3 1.5e-10 41.1 0.2 2.1 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 KNZ77959.1 - 9e-08 31.0 0.1 1.1e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KNZ77959.1 - 0.033 13.4 0.1 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DUF2363 PF10155.4 KNZ77960.1 - 0.0035 17.2 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) Pkinase PF00069.20 KNZ77961.1 - 3.1e-74 249.4 0.3 3.1e-74 249.4 0.2 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77961.1 - 4.2e-53 180.0 0.3 4.2e-53 180.0 0.2 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 KNZ77961.1 - 2.8e-22 78.8 0.0 1e-21 77.1 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 KNZ77961.1 - 4.2e-08 32.4 0.0 8.2e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ77961.1 - 0.00063 19.5 3.4 0.0018 18.0 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family PH PF00169.24 KNZ77961.1 - 0.0044 17.2 0.2 0.011 15.9 0.2 1.7 1 0 0 1 1 1 1 PH domain DUF1777 PF08648.7 KNZ77961.1 - 0.0057 16.4 17.4 0.0096 15.6 12.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Seadorna_VP7 PF07387.6 KNZ77961.1 - 0.014 14.2 0.2 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2413 PF10310.4 KNZ77961.1 - 0.39 9.4 15.6 0.6 8.8 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF3043 PF11241.3 KNZ77961.1 - 7.8 6.0 16.1 14 5.2 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PGA2 PF07543.7 KNZ77962.1 - 0.27 11.0 6.2 0.98 9.2 1.2 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 IBR PF01485.16 KNZ77964.1 - 2.2e-10 40.2 24.8 4.2e-07 29.7 9.1 2.1 2 0 0 2 2 2 2 IBR domain Phosphorylase PF00343.15 KNZ77967.1 - 6.1e-301 999.5 0.0 7.2e-301 999.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF1708 PF08101.6 KNZ77968.1 - 1.1e-15 57.4 0.0 6.8e-15 54.8 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) DXP_synthase_N PF13292.1 KNZ77968.1 - 0.55 9.1 0.1 1 8.2 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase STE PF02200.11 KNZ77969.1 - 1.7e-57 192.3 0.1 2.9e-57 191.5 0.0 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 KNZ77969.1 - 4e-12 45.7 11.6 3.4e-06 27.0 1.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ77969.1 - 6.2e-12 44.9 8.6 7.5e-06 25.9 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KNZ77969.1 - 5.1e-09 35.9 13.8 3.4e-08 33.3 2.9 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KNZ77969.1 - 0.00048 20.1 4.7 0.085 13.0 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KNZ77969.1 - 0.005 16.6 0.3 0.015 15.1 0.2 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.7 KNZ77969.1 - 0.025 14.6 1.5 0.045 13.8 1.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 KNZ77969.1 - 0.11 12.7 5.6 0.75 10.0 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KNZ77969.1 - 0.72 9.9 3.6 5.1 7.2 2.5 2.1 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF1628 PF07790.6 KNZ77970.1 - 0.0053 17.4 0.2 0.015 15.9 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1628) ELFV_dehydrog_N PF02812.13 KNZ77970.1 - 0.055 13.0 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Tad PF13400.1 KNZ77970.1 - 0.069 13.1 0.8 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Herpes_gE PF02480.11 KNZ77971.1 - 3.3e-06 25.6 0.0 6.1e-06 24.7 0.0 1.4 1 1 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KNZ77971.1 - 0.016 15.5 0.0 0.031 14.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 KNZ77971.1 - 0.019 13.7 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) TMEM154 PF15102.1 KNZ77971.1 - 0.023 14.4 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF4328 PF14219.1 KNZ77971.1 - 0.072 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) EssA PF10661.4 KNZ77971.1 - 0.14 11.8 0.1 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA SRP9-21 PF05486.7 KNZ77972.1 - 4.1e-17 61.6 0.8 5.4e-17 61.3 0.6 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Pou PF00157.12 KNZ77972.1 - 0.13 11.8 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Mito_carr PF00153.22 KNZ77973.1 - 7.9e-63 208.2 3.6 3.3e-22 77.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 KNZ77974.1 - 3e-44 151.1 0.0 5.3e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ77974.1 - 9.9e-39 132.9 0.0 1.6e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ77974.1 - 0.0054 16.4 0.1 0.0054 16.4 0.1 2.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KNZ77974.1 - 0.03 13.2 0.0 0.058 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KNZ77974.1 - 0.12 11.4 0.0 0.29 10.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rhodanese PF00581.15 KNZ77975.1 - 1.6e-06 28.4 0.0 3.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain DUF1687 PF07955.6 KNZ77976.1 - 2.5e-06 27.4 0.0 7.2e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) RNase_T PF00929.19 KNZ77976.1 - 0.058 13.6 1.3 0.55 10.4 0.9 2.4 1 1 0 1 1 1 0 Exonuclease Aldolase_II PF00596.16 KNZ77977.1 - 1.9e-42 144.9 0.1 2.5e-42 144.5 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Phosphoesterase PF04185.9 KNZ77978.1 - 2e-33 116.0 2.8 2.7e-33 115.7 2.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.18 KNZ77978.1 - 0.0052 16.0 0.2 0.0067 15.6 0.1 1.2 1 0 0 1 1 1 1 Sulfatase SNF2_N PF00176.18 KNZ77979.1 - 7.8e-44 149.6 0.1 2.4e-43 148.0 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain ApoO PF09769.4 KNZ77979.1 - 6.2e-31 107.2 0.0 1.4e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 Apolipoprotein O Helicase_C PF00271.26 KNZ77979.1 - 4.2e-14 52.1 0.0 2.4e-13 49.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KNZ77979.1 - 3.5e-08 32.6 0.0 7.8e-08 31.4 0.0 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.24 KNZ77979.1 - 0.00072 19.1 7.2 0.00072 19.1 5.0 2.8 2 1 1 3 3 3 1 PHD-finger DUF3638 PF12340.3 KNZ77980.1 - 1.5e-74 249.8 0.1 3.1e-74 248.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KNZ77980.1 - 1.1e-14 53.2 0.0 2.5e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Dynamitin PF04912.9 KNZ77980.1 - 0.014 14.1 0.3 0.056 12.2 0.2 1.8 2 0 0 2 2 2 0 Dynamitin DUF3584 PF12128.3 KNZ77980.1 - 0.3 8.3 1.2 0.52 7.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3638 PF12340.3 KNZ77981.1 - 4.5e-80 267.9 0.1 8.3e-80 267.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KNZ77981.1 - 1.1e-14 53.1 0.0 2.8e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) PCMT PF01135.14 KNZ77981.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RVP_2 PF08284.6 KNZ77982.1 - 0.00032 20.6 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KNZ77983.1 - 0.0011 18.6 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ77983.1 - 0.0025 18.2 0.0 0.0064 16.9 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease NAD_binding_4 PF07993.7 KNZ77985.1 - 9e-27 93.5 0.0 1.4e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KNZ77985.1 - 4.4e-20 71.4 0.1 6.5e-20 70.9 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KNZ77985.1 - 1.4e-08 34.4 0.0 2.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ77985.1 - 0.00011 22.3 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 NADH(P)-binding Shikimate_DH PF01488.15 KNZ77985.1 - 0.056 13.5 0.0 0.24 11.5 0.0 2.1 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KNZ77985.1 - 0.13 12.1 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 short chain dehydrogenase 3Beta_HSD PF01073.14 KNZ77985.1 - 0.14 10.8 0.0 0.24 10.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KNZ77985.1 - 0.19 10.5 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.17 KNZ77986.1 - 1.8e-16 59.7 0.0 2.2e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NUP PF06516.6 KNZ77987.1 - 4.9e-100 334.3 0.0 5.9e-100 334.1 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Acyl_transf_1 PF00698.16 KNZ77989.1 - 0.16 11.3 1.0 0.22 10.7 0.7 1.2 1 0 0 1 1 1 0 Acyl transferase domain LRR_1 PF00560.28 KNZ77989.1 - 0.64 10.2 2.3 0.58 10.3 0.3 2.0 2 0 0 2 2 2 0 Leucine Rich Repeat zf-C3HC4_3 PF13920.1 KNZ77994.1 - 4.1e-13 48.7 20.4 5.2e-13 48.4 4.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KNZ77994.1 - 6e-08 32.4 6.6 6e-08 32.4 4.6 2.9 2 1 0 2 2 2 1 FYVE zinc finger zf-C3HC4_2 PF13923.1 KNZ77994.1 - 4.7e-07 29.7 7.2 4.7e-07 29.7 5.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ77994.1 - 3.4e-06 26.7 5.6 3.4e-06 26.7 3.9 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KNZ77994.1 - 3.8e-05 23.2 6.6 3.8e-05 23.2 4.6 3.2 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 KNZ77994.1 - 0.00029 20.7 4.1 0.00029 20.7 2.8 3.2 3 0 0 3 3 3 1 FYVE-type zinc finger zf-P11 PF03854.9 KNZ77994.1 - 0.0025 17.2 2.7 0.0025 17.2 1.9 2.6 2 0 0 2 2 2 1 P-11 zinc finger Armet PF10208.4 KNZ77994.1 - 0.0026 17.4 0.2 0.082 12.5 0.0 2.3 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding Prok-RING_4 PF14447.1 KNZ77994.1 - 0.0045 16.4 1.1 0.0045 16.4 0.8 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 Rho_N PF07498.7 KNZ77994.1 - 0.035 13.8 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Menin PF05053.8 KNZ77994.1 - 0.075 11.1 3.5 0.098 10.8 2.4 1.2 1 0 0 1 1 1 0 Menin zf-RING_5 PF14634.1 KNZ77994.1 - 0.36 10.5 22.1 0.028 14.1 3.9 2.7 2 0 0 2 2 2 0 zinc-RING finger domain Prp19_bind PF06991.6 KNZ77994.1 - 0.42 9.8 12.6 1.8 7.7 6.6 2.1 2 0 0 2 2 2 0 Splicing factor, Prp19-binding domain zf-UDP PF14569.1 KNZ77994.1 - 1.7 8.4 12.0 1.3 8.8 0.5 3.0 2 1 0 2 2 2 0 Zinc-binding RING-finger zf-MYND PF01753.13 KNZ77995.1 - 1.2e-08 34.6 10.3 2e-08 33.9 7.2 1.3 1 0 0 1 1 1 1 MYND finger TPR_11 PF13414.1 KNZ77995.1 - 0.001 18.6 0.6 0.98 9.1 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KNZ77995.1 - 0.0027 17.4 2.0 0.53 10.3 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ77995.1 - 0.08 12.8 1.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat CHCH PF06747.8 KNZ77996.1 - 0.003 17.4 2.6 0.0051 16.6 1.3 1.7 1 1 1 2 2 2 2 CHCH domain DUF2076 PF09849.4 KNZ77996.1 - 0.011 15.7 0.7 0.013 15.5 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) zinc-ribbons_6 PF07191.7 KNZ77996.1 - 0.1 12.3 2.6 0.16 11.7 1.8 1.3 1 0 0 1 1 1 0 zinc-ribbons MBA1 PF07961.6 KNZ77997.1 - 7.3e-07 28.2 0.0 1.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 KNZ77997.1 - 0.0022 17.9 1.0 1.3 8.9 0.0 3.2 2 1 1 3 3 3 2 Tim44-like domain Terpene_synth_C PF03936.11 KNZ77998.1 - 3.5e-17 62.5 0.0 5.1e-17 61.9 0.0 1.3 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain MFS_1 PF07690.11 KNZ77999.1 - 4.4e-24 84.8 29.0 5.7e-20 71.3 5.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ77999.1 - 8.8e-07 27.8 11.7 8.8e-07 27.8 8.1 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter DUF2160 PF09928.4 KNZ77999.1 - 0.025 14.6 1.7 0.31 11.1 0.0 2.8 2 1 0 2 2 2 0 Predicted small integral membrane protein (DUF2160) MFS_1_like PF12832.2 KNZ77999.1 - 0.047 13.4 0.2 0.047 13.4 0.1 2.9 4 0 0 4 4 4 0 MFS_1 like family DEAD PF00270.24 KNZ78000.1 - 2.2e-39 134.6 0.0 3.9e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ78000.1 - 3e-23 81.4 0.0 1.9e-21 75.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ78000.1 - 0.0048 16.7 0.0 0.018 14.8 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KNZ78000.1 - 0.073 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain NDUF_B7 PF05676.8 KNZ78001.1 - 4.6e-30 102.8 1.7 5.4e-30 102.6 1.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KNZ78001.1 - 0.013 15.3 2.5 0.017 14.8 1.7 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like WD40 PF00400.27 KNZ78002.1 - 4.8e-59 194.2 21.6 9.4e-12 44.3 0.1 13.1 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 KNZ78002.1 - 6.7e-19 67.8 0.0 1e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KNZ78002.1 - 8.1e-07 28.9 0.5 1.2 8.8 0.0 5.0 4 2 1 6 6 6 4 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KNZ78002.1 - 0.0099 13.7 0.0 5 4.8 0.0 3.3 2 1 1 3 3 3 2 IKI3 family Cytochrom_D1 PF02239.11 KNZ78002.1 - 0.033 12.4 2.0 12 4.1 0.1 4.0 3 1 1 4 4 4 0 Cytochrome D1 heme domain PD40 PF07676.7 KNZ78002.1 - 0.042 13.5 3.6 6.6 6.5 0.0 5.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 KNZ78002.1 - 0.046 12.3 0.2 0.36 9.3 0.0 2.6 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region RAB3GAP2_N PF14655.1 KNZ78002.1 - 0.11 11.5 0.0 1 8.3 0.0 2.6 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1513 PF07433.6 KNZ78002.1 - 0.24 10.2 0.7 12 4.7 0.0 3.4 5 0 0 5 5 5 0 Protein of unknown function (DUF1513) Sdh5 PF03937.11 KNZ78003.1 - 4.9e-26 90.2 0.4 6.1e-26 89.9 0.2 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase O-FucT PF10250.4 KNZ78006.1 - 4.1e-09 36.0 0.0 6.8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Gly_transf_sug PF04488.10 KNZ78007.1 - 7.4e-07 29.5 0.1 1.2e-06 28.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KNZ78007.1 - 4.9e-05 22.6 0.1 6.8e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein DEAD PF00270.24 KNZ78008.1 - 7.4e-43 145.9 0.2 1.2e-42 145.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ78008.1 - 5.7e-24 83.7 0.1 1.2e-23 82.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KNZ78008.1 - 0.0068 15.5 0.3 0.017 14.1 0.2 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit PIF1 PF05970.9 KNZ78013.1 - 2.3e-33 115.6 0.0 2.5e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 KNZ78014.1 - 9.4e-07 26.9 0.0 9.9e-07 26.9 0.0 1.0 1 0 0 1 1 1 1 Helicase ATG11 PF10377.4 KNZ78015.1 - 1.3e-32 112.3 1.2 3.3e-32 111.0 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein 11 IFP_35_N PF07334.8 KNZ78015.1 - 5.5 7.0 10.1 3.9 7.5 0.9 3.6 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Cast PF10174.4 KNZ78015.1 - 7.4 4.4 55.9 1.1 7.2 35.2 2.1 2 1 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Sugar_tr PF00083.19 KNZ78016.1 - 7.8e-88 295.0 18.2 9e-88 294.8 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ78016.1 - 4.4e-27 94.7 41.9 3.7e-25 88.3 16.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Metallophos PF00149.23 KNZ78017.1 - 2.6e-44 151.0 0.1 3.3e-44 150.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PH_9 PF15410.1 KNZ78018.1 - 4.7e-06 26.7 0.0 0.014 15.5 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 KNZ78018.1 - 0.0016 18.6 0.0 5.4 7.3 0.0 3.5 3 0 0 3 3 3 2 Pleckstrin homology domain PH PF00169.24 KNZ78018.1 - 0.038 14.1 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 PH domain SLEI_Leptospira PF07620.6 KNZ78019.1 - 0.42 10.5 4.1 3.6 7.5 0.2 2.4 2 0 0 2 2 2 0 SLEI DUF2881 PF11087.3 KNZ78019.1 - 1.3 8.5 6.4 0.13 11.7 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2881) HAD_2 PF13419.1 KNZ78022.1 - 1.4e-13 51.4 0.0 4.6e-13 49.7 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase UTRA PF07702.8 KNZ78022.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 UTRA domain RNA_pol_N PF01194.12 KNZ78023.1 - 3.2e-30 103.9 0.3 3.7e-30 103.7 0.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit EF-hand_4 PF12763.2 KNZ78024.1 - 2.7e-15 55.9 0.0 1.3e-09 37.6 0.0 3.0 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KNZ78024.1 - 0.00015 21.8 2.4 0.025 14.7 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain pair Myosin_tail_1 PF01576.14 KNZ78024.1 - 0.0019 16.0 49.4 0.01 13.5 23.0 2.4 1 1 1 2 2 2 2 Myosin tail CCDC155 PF14662.1 KNZ78024.1 - 0.006 16.2 55.5 0.38 10.3 3.0 3.8 2 1 0 3 3 3 3 Coiled-coil region of CCDC155 Phage_GP20 PF06810.6 KNZ78024.1 - 0.01 15.3 3.6 0.01 15.3 2.5 4.8 1 1 4 5 5 5 0 Phage minor structural protein GP20 EF-hand_1 PF00036.27 KNZ78024.1 - 0.032 13.5 0.2 4.6 6.7 0.0 2.6 2 0 0 2 2 2 0 EF hand BLOC1_2 PF10046.4 KNZ78024.1 - 0.049 13.7 35.1 0.24 11.5 2.5 5.3 1 1 4 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.1 KNZ78024.1 - 0.14 11.3 45.8 0.083 12.0 12.1 3.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 KNZ78024.1 - 0.15 10.4 30.4 0.57 8.5 5.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF342) AAA_13 PF13166.1 KNZ78024.1 - 0.97 7.8 33.3 0.18 10.2 10.7 2.2 1 1 1 2 2 2 0 AAA domain gpW PF02831.10 KNZ78024.1 - 1.8 8.1 10.2 3.2 7.3 0.3 3.7 4 0 0 4 4 4 0 gpW CENP-F_leu_zip PF10473.4 KNZ78024.1 - 9.7 6.0 55.5 2.8 7.8 5.4 5.0 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMG_box PF00505.14 KNZ78025.1 - 2e-11 44.0 0.8 2e-10 40.7 0.1 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KNZ78025.1 - 0.033 14.5 0.1 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 HMG-box domain Sec2p PF06428.6 KNZ78026.1 - 1.9e-13 50.1 10.4 1.9e-13 50.1 7.2 2.4 1 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF1704 PF08014.6 KNZ78026.1 - 0.018 14.0 6.6 0.025 13.6 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) DUF4140 PF13600.1 KNZ78026.1 - 0.54 10.7 16.0 0.21 12.0 7.7 2.4 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.3 KNZ78026.1 - 1.1 9.0 0.0 1.1 9.0 0.0 3.8 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.6 KNZ78026.1 - 1.6 8.4 12.6 0.74 9.5 1.8 2.9 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 HALZ PF02183.13 KNZ78026.1 - 1.9 8.2 9.8 3.7 7.3 0.1 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Spc7 PF08317.6 KNZ78026.1 - 2.9 6.4 17.3 1.4 7.5 8.5 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein ATP-synt_E PF05680.7 KNZ78026.1 - 5.3 7.0 11.1 3.1 7.8 3.5 2.3 2 0 0 2 2 2 0 ATP synthase E chain DUF972 PF06156.8 KNZ78026.1 - 6.3 7.1 16.5 1.3 9.4 3.4 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Herpes_UL6 PF01763.11 KNZ78026.1 - 6.6 4.7 12.6 0.16 10.0 1.2 2.1 1 1 1 2 2 2 0 Herpesvirus UL6 like HR1 PF02185.11 KNZ78026.1 - 8 6.2 20.0 0.17 11.6 0.9 3.7 2 2 2 4 4 4 0 Hr1 repeat DFP PF04127.10 KNZ78027.1 - 3.3e-18 65.9 0.0 6.1e-08 32.4 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein Pkinase PF00069.20 KNZ78028.1 - 1.3e-35 122.8 0.0 1.8e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ78028.1 - 1.7e-16 60.0 0.0 2.3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KNZ78028.1 - 0.00011 21.0 0.1 0.00017 20.5 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 KNZ78028.1 - 0.0013 17.7 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ78028.1 - 0.034 13.8 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family TENA_THI-4 PF03070.11 KNZ78029.1 - 1.2e-09 38.2 0.2 1.5e-09 37.8 0.2 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Zn_clus PF00172.13 KNZ78030.1 - 1.3e-05 25.0 9.4 2.3e-05 24.2 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 KNZ78030.1 - 0.00042 20.0 0.0 0.0063 16.2 0.0 2.7 3 0 0 3 3 3 1 PAS fold Formyl_trans_N PF00551.14 KNZ78031.1 - 2.1e-23 82.8 0.0 3e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 KNZ78031.1 - 4.4e-09 36.3 0.0 7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DUF221 PF02714.10 KNZ78034.1 - 1.6e-105 352.5 19.2 2.5e-105 351.9 13.3 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KNZ78034.1 - 2.6e-40 137.5 4.4 2.6e-40 137.5 3.0 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KNZ78034.1 - 6.9e-18 64.9 0.1 1.3e-17 64.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 KNZ78034.1 - 3.9e-15 55.4 0.0 8.8e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF155 PF02582.9 KNZ78035.1 - 9e-47 159.2 0.0 2.2e-46 157.9 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 KNZ78035.1 - 0.071 13.3 1.1 0.17 12.1 0.0 2.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 RmlD_sub_bind PF04321.12 KNZ78036.1 - 8.3e-29 100.3 0.0 1.1e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KNZ78036.1 - 7.5e-06 25.5 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RNase_H PF00075.19 KNZ78036.1 - 2.1e-05 24.8 0.0 3.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 RNase H Imm_superinfect PF14373.1 KNZ78037.1 - 0.23 11.0 1.2 0.48 10.1 0.8 1.5 1 0 0 1 1 1 0 Superinfection immunity protein Sec16 PF12932.2 KNZ78039.1 - 0.093 12.6 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region Helitron_like_N PF14214.1 KNZ78040.1 - 3e-63 212.8 0.3 8.7e-63 211.3 0.1 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 KNZ78040.1 - 1.5e-06 27.1 0.0 2.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) Tom22 PF04281.8 KNZ78041.1 - 0.074 12.5 0.7 0.081 12.4 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 His_Phos_2 PF00328.17 KNZ78044.1 - 2e-88 297.0 0.1 2.6e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KNZ78044.1 - 2e-06 27.3 0.0 4.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Chromo PF00385.19 KNZ78045.1 - 1.9e-17 62.6 0.3 2.2e-17 62.4 0.2 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RasGAP PF00616.14 KNZ78048.1 - 1.6e-34 119.3 0.1 3.3e-34 118.2 0.1 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KNZ78048.1 - 8.9e-18 64.3 0.3 6.1e-08 32.4 0.1 2.7 1 1 1 2 2 2 2 RasGAP C-terminus IQ PF00612.22 KNZ78048.1 - 2.8e-14 51.3 27.9 0.0088 15.6 0.1 9.4 9 0 0 9 9 9 7 IQ calmodulin-binding motif CH PF00307.26 KNZ78048.1 - 6.2e-11 42.2 0.0 2.1e-10 40.5 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain MFS_1 PF07690.11 KNZ78049.1 - 2.2e-10 39.8 16.8 1.3e-09 37.2 11.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sec62 PF03839.11 KNZ78049.1 - 0.1 12.0 0.1 2.5 7.4 0.1 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 zf-RVT PF13966.1 KNZ78050.1 - 0.0013 19.0 0.9 0.0024 18.1 0.6 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Cytochrom_NNT PF03264.9 KNZ78050.1 - 0.035 13.5 1.4 0.054 12.9 1.0 1.2 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region E1-E2_ATPase PF00122.15 KNZ78051.1 - 1.1e-47 162.0 0.0 2.5e-47 160.8 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KNZ78051.1 - 9.6e-37 127.4 0.0 1.4e-36 126.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KNZ78051.1 - 2.5e-18 65.9 1.5 3.4e-08 33.4 0.3 3.9 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.2 KNZ78051.1 - 3.6e-15 56.6 0.0 6.8e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KNZ78051.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-CHY PF05495.7 KNZ78051.1 - 0.003 17.6 3.5 0.003 17.6 2.4 1.7 2 0 0 2 2 2 1 CHY zinc finger ABC_tran PF00005.22 KNZ78053.1 - 1.1e-15 58.1 0.0 3.9e-15 56.3 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KNZ78053.1 - 3.8e-08 33.6 0.2 3.3e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KNZ78053.1 - 0.00027 20.4 0.0 0.0006 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KNZ78053.1 - 0.00042 19.7 0.1 0.00078 18.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KNZ78053.1 - 0.00076 18.7 0.0 0.0074 15.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 KNZ78053.1 - 0.002 18.4 0.0 0.0038 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KNZ78053.1 - 0.0038 16.3 0.0 0.023 13.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 KNZ78053.1 - 0.0044 16.2 0.8 0.23 10.6 0.1 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain MutS_V PF00488.16 KNZ78053.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 MutS domain V AAA_28 PF13521.1 KNZ78053.1 - 0.039 13.9 0.0 0.096 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KNZ78053.1 - 0.041 13.3 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 KNZ78053.1 - 0.046 13.2 0.0 0.049 13.1 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 KNZ78053.1 - 0.049 14.4 0.3 0.049 14.4 0.2 2.4 3 1 0 3 3 2 0 AAA domain ABC_ATPase PF09818.4 KNZ78053.1 - 0.056 12.0 1.1 0.13 10.8 0.0 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_18 PF13238.1 KNZ78053.1 - 0.069 13.4 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KNZ78053.1 - 0.085 13.0 0.5 0.53 10.4 0.3 2.1 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KNZ78053.1 - 0.086 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KNZ78053.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein NACHT PF05729.7 KNZ78053.1 - 0.12 11.9 0.2 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Arf PF00025.16 KNZ78053.1 - 0.13 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_13 PF13166.1 KNZ78053.1 - 0.14 10.6 0.0 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Opy2 PF09463.5 KNZ78054.1 - 0.55 10.3 17.2 0.9 9.6 11.9 1.4 1 0 0 1 1 1 0 Opy2 protein DUF3818 PF12825.2 KNZ78056.1 - 5.4e-110 367.2 1.5 9.2e-109 363.2 1.1 2.1 1 1 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KNZ78056.1 - 3.4e-28 97.9 0.0 8.5e-28 96.6 0.0 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.19 KNZ78056.1 - 1.6e-10 40.7 0.3 3.1e-09 36.5 0.0 3.0 3 0 0 3 3 3 1 PX domain DUF572 PF04502.8 KNZ78056.1 - 0.1 11.8 7.1 0.18 10.9 4.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Nop14 PF04147.7 KNZ78056.1 - 1.8 6.3 13.6 0.32 8.8 6.0 1.9 2 0 0 2 2 2 0 Nop14-like family Chromo PF00385.19 KNZ78057.1 - 3.6e-11 42.5 0.0 5.8e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3151 PF11349.3 KNZ78057.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3151) RVP_2 PF08284.6 KNZ78060.1 - 0.0077 16.1 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KNZ78060.1 - 0.008 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ78060.1 - 0.025 15.0 0.0 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease DEAD PF00270.24 KNZ78062.1 - 1.1e-31 109.6 0.3 2.8e-31 108.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KNZ78062.1 - 4e-21 74.3 0.0 8.4e-21 73.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KNZ78062.1 - 6.1e-19 67.6 0.0 1.7e-18 66.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ78062.1 - 0.00092 19.0 0.6 0.0018 18.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KNZ78062.1 - 0.03 14.0 0.0 0.087 12.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Pkinase PF00069.20 KNZ78063.1 - 8.4e-62 208.6 0.0 9.6e-41 139.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ78063.1 - 1.9e-24 86.1 0.6 6.6e-18 64.7 0.1 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KNZ78063.1 - 3.2e-05 23.0 0.1 0.00034 19.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KNZ78063.1 - 5.8e-05 22.2 0.1 0.00052 19.1 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ78063.1 - 0.00037 20.3 0.3 0.021 14.5 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 KNZ78063.1 - 0.0034 17.8 0.5 0.0095 16.4 0.4 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain RIO1 PF01163.17 KNZ78063.1 - 0.018 14.4 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 KNZ78063.1 - 0.018 13.8 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 KNZ78063.1 - 0.047 12.5 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 BCDHK_Adom3 PF10436.4 KNZ78065.1 - 4.5e-34 117.3 0.0 7.8e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KNZ78065.1 - 4.9e-08 32.6 0.0 1.7e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2786 PF10979.3 KNZ78066.1 - 0.16 11.7 2.0 0.23 11.1 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) UBN2_2 PF14227.1 KNZ78067.1 - 6.8e-05 22.4 0.1 6.8e-05 22.4 0.1 2.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Proho_convert PF12177.3 KNZ78068.1 - 0.11 12.0 0.7 0.3 10.7 0.3 1.8 2 0 0 2 2 2 0 Prohormone convertase enzyme WD40 PF00400.27 KNZ78071.1 - 1.9e-163 525.2 92.7 5.8e-14 51.3 0.3 13.6 13 0 0 13 13 13 13 WD domain, G-beta repeat PQQ_2 PF13360.1 KNZ78071.1 - 9.6e-18 64.5 16.8 1.6e-05 24.5 2.9 5.4 1 1 4 5 5 5 5 PQQ-like domain DUF3312 PF11768.3 KNZ78071.1 - 3.3e-15 55.3 4.2 0.83 7.7 0.0 9.9 1 1 11 12 12 12 7 Protein of unknown function (DUF3312) PD40 PF07676.7 KNZ78071.1 - 8.8e-14 50.8 6.9 29 4.4 0.0 12.9 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat NACHT PF05729.7 KNZ78071.1 - 2e-10 40.5 0.1 5.6e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KNZ78071.1 - 3.2e-06 27.2 0.0 1.1e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain Crystall_2 PF09076.5 KNZ78071.1 - 0.00016 21.3 8.4 4.7 7.0 0.1 6.2 3 3 6 9 9 9 1 Beta/Gamma crystallin AAA_22 PF13401.1 KNZ78071.1 - 0.00037 20.6 0.0 0.0013 18.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 KNZ78071.1 - 0.00067 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 KNZ78071.1 - 0.0041 17.9 0.0 0.017 15.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KNZ78071.1 - 0.0075 15.9 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 KNZ78071.1 - 0.0093 15.4 0.0 0.048 13.1 0.0 2.3 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA PF00004.24 KNZ78071.1 - 0.023 14.9 0.0 0.1 12.7 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KNZ78071.1 - 0.032 14.5 0.1 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KNZ78071.1 - 0.11 11.9 0.1 0.37 10.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KNZ78071.1 - 0.28 10.7 0.0 0.59 9.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KNZ78071.1 - 0.33 10.0 0.0 0.95 8.5 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin UPF0180 PF03698.8 KNZ78071.1 - 0.44 10.4 9.9 25 4.7 0.0 6.9 8 3 1 9 9 9 0 Uncharacterised protein family (UPF0180) AAA_23 PF13476.1 KNZ78071.1 - 3 8.1 5.5 1.5 9.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain DUF3253 PF11625.3 KNZ78072.1 - 0.0022 17.8 0.1 0.0057 16.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) TelA PF05816.6 KNZ78072.1 - 0.0022 16.7 2.8 0.0035 16.1 1.9 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Suf PF05843.9 KNZ78072.1 - 0.0023 17.7 2.0 0.0045 16.7 1.4 1.6 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DivIVA PF05103.8 KNZ78072.1 - 0.35 10.9 4.8 1 9.4 3.3 1.8 1 0 0 1 1 1 0 DivIVA protein SKG6 PF08693.5 KNZ78073.1 - 0.041 13.2 0.2 0.15 11.3 0.1 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 KNZ78073.1 - 0.16 11.5 0.2 0.34 10.4 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.15 KNZ78073.1 - 0.16 11.6 0.0 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain TFIIA PF03153.8 KNZ78073.1 - 7.3 6.3 9.0 14 5.4 6.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIF1 PF05970.9 KNZ78074.1 - 9.7e-56 189.2 0.1 1.1e-55 189.0 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 KNZ78074.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helitron_like_N PF14214.1 KNZ78075.1 - 1.6e-56 191.0 0.3 2.8e-56 190.1 0.1 1.5 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 KNZ78075.1 - 5.6e-08 31.8 0.0 1e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) WD40 PF00400.27 KNZ78077.1 - 6.5e-76 247.7 41.9 1.2e-13 50.3 0.3 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat NACHT PF05729.7 KNZ78077.1 - 1.8e-08 34.1 0.0 8.2e-08 32.0 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KNZ78077.1 - 2.8e-06 27.4 0.0 9.2e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain PD40 PF07676.7 KNZ78077.1 - 9.4e-06 25.1 0.4 26 4.5 0.0 5.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat AAA_22 PF13401.1 KNZ78077.1 - 0.0003 20.9 0.2 0.0019 18.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain APS_kinase PF01583.15 KNZ78077.1 - 0.00053 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.24 KNZ78077.1 - 0.0009 19.4 0.0 0.01 16.0 0.0 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytochrom_D1 PF02239.11 KNZ78077.1 - 0.0011 17.3 0.3 0.36 9.0 0.0 3.1 1 1 2 3 3 3 1 Cytochrome D1 heme domain AAA_17 PF13207.1 KNZ78077.1 - 0.0022 18.8 0.0 0.013 16.3 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 KNZ78077.1 - 0.0043 16.5 0.0 0.036 13.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KNZ78077.1 - 0.0044 17.3 0.5 0.12 12.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KNZ78077.1 - 0.0049 16.6 0.0 0.017 14.8 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KNZ78077.1 - 0.017 14.5 0.0 0.063 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KNZ78077.1 - 0.047 13.8 0.0 0.21 11.7 0.0 2.2 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 KNZ78077.1 - 0.098 12.9 1.1 0.82 9.9 0.0 2.7 3 0 0 3 3 3 0 ABC transporter AAA_14 PF13173.1 KNZ78077.1 - 0.11 12.4 0.0 0.48 10.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KNZ78077.1 - 0.11 12.0 0.0 0.38 10.3 0.0 1.8 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 KNZ78077.1 - 0.16 11.0 0.0 0.46 9.5 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.1 KNZ78077.1 - 1.2 9.3 6.0 1.7 8.8 0.0 2.5 1 1 1 2 2 2 0 AAA domain Herpes_gE PF02480.11 KNZ78078.1 - 0.015 13.5 0.0 0.021 13.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Gly-zipper_Omp PF13488.1 KNZ78078.1 - 0.019 14.6 2.1 0.019 14.6 1.5 3.9 3 0 0 3 3 3 0 Glycine zipper Adeno_E3_CR2 PF02439.10 KNZ78078.1 - 0.022 14.2 0.1 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Gly-zipper_OmpA PF13436.1 KNZ78078.1 - 1.5 8.5 14.4 1.2 8.8 0.1 3.3 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain WD40 PF00400.27 KNZ78079.1 - 3.4e-192 616.3 112.0 1.9e-14 52.8 0.1 16.8 16 0 0 16 16 16 15 WD domain, G-beta repeat PD40 PF07676.7 KNZ78079.1 - 7.6e-15 54.1 6.3 67 3.2 0.0 14.9 16 0 0 16 16 16 0 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 KNZ78079.1 - 1.4e-14 53.2 7.7 0.22 9.7 0.0 8.9 2 1 9 11 11 11 8 Protein of unknown function (DUF3312) NACHT PF05729.7 KNZ78079.1 - 7.6e-11 41.9 0.0 2.2e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KNZ78079.1 - 2e-06 27.9 0.0 6.8e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain UPF0180 PF03698.8 KNZ78079.1 - 0.00049 19.8 5.3 15 5.4 0.0 7.2 7 1 0 8 8 8 0 Uncharacterised protein family (UPF0180) AAA_22 PF13401.1 KNZ78079.1 - 0.00052 20.1 0.0 0.0025 17.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KNZ78079.1 - 0.00087 19.0 0.0 0.0028 17.3 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain APS_kinase PF01583.15 KNZ78079.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 KNZ78079.1 - 0.0017 19.1 0.0 0.0066 17.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 KNZ78079.1 - 0.0087 16.3 0.3 0.057 13.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KNZ78079.1 - 0.012 15.1 0.0 0.057 12.9 0.0 2.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 KNZ78079.1 - 0.017 14.5 0.0 0.046 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KNZ78079.1 - 0.038 14.2 0.0 0.16 12.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KNZ78079.1 - 0.17 11.4 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF433 PF04255.9 KNZ78079.1 - 0.19 11.1 0.0 0.99 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF433) AAA_23 PF13476.1 KNZ78079.1 - 1.3 9.3 5.0 1.7 8.9 0.0 2.5 1 1 1 2 2 2 0 AAA domain Crystall_2 PF09076.5 KNZ78079.1 - 7.7 6.3 23.1 17 5.2 0.3 7.4 7 2 2 9 9 8 0 Beta/Gamma crystallin Asp_protease_2 PF13650.1 KNZ78082.1 - 0.00038 20.9 0.0 0.00038 20.8 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KNZ78082.1 - 0.055 13.2 0.0 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 KNZ78082.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease SKG6 PF08693.5 KNZ78083.1 - 0.16 11.3 0.2 0.16 11.3 0.1 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Syndecan PF01034.15 KNZ78083.1 - 0.16 11.6 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.10 KNZ78083.1 - 0.16 11.5 0.2 0.34 10.4 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 KNZ78083.1 - 0.22 11.9 0.3 0.57 10.6 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain WD40 PF00400.27 KNZ78084.1 - 4.6e-185 593.7 78.2 1.1e-14 53.6 0.2 14.6 14 0 0 14 14 14 14 WD domain, G-beta repeat PD40 PF07676.7 KNZ78084.1 - 2.1e-12 46.4 8.9 28 4.5 0.0 13.5 14 0 0 14 14 14 0 WD40-like Beta Propeller Repeat NACHT PF05729.7 KNZ78084.1 - 6.9e-10 38.8 0.0 2.2e-09 37.1 0.0 1.9 1 1 0 1 1 1 1 NACHT domain DUF3312 PF11768.3 KNZ78084.1 - 4.5e-08 31.7 0.1 0.65 8.1 0.0 6.3 3 2 3 7 7 7 2 Protein of unknown function (DUF3312) AAA_16 PF13191.1 KNZ78084.1 - 2.1e-06 27.8 0.1 8.1e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KNZ78084.1 - 0.00059 20.6 0.0 0.0049 17.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KNZ78084.1 - 0.00064 19.4 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain APS_kinase PF01583.15 KNZ78084.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_29 PF13555.1 KNZ78084.1 - 0.005 16.3 0.0 0.044 13.3 0.0 2.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KNZ78084.1 - 0.0051 16.2 0.0 0.025 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KNZ78084.1 - 0.0089 16.1 0.0 0.03 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KNZ78084.1 - 0.034 14.3 0.2 0.24 11.5 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KNZ78084.1 - 0.037 14.3 0.3 0.17 12.1 0.0 2.3 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.12 KNZ78084.1 - 0.043 13.3 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 KNZ78084.1 - 0.15 11.6 0.0 0.43 10.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain PQQ_3 PF13570.1 KNZ78084.1 - 0.38 11.1 25.0 23 5.4 0.1 10.2 11 2 2 13 13 13 0 PQQ-like domain AAA_23 PF13476.1 KNZ78084.1 - 2.3 8.5 0.0 2.3 8.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain F-box-like PF12937.2 KNZ78086.1 - 1.6e-09 37.3 0.5 4.8e-09 35.8 0.1 2.0 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 KNZ78086.1 - 0.034 13.8 3.3 6.7 6.5 0.3 3.5 3 0 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.2 KNZ78087.1 - 3.8e-08 32.9 0.8 1.1e-07 31.4 0.6 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KNZ78087.1 - 0.071 12.7 0.6 0.53 9.9 0.2 2.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) adh_short PF00106.20 KNZ78088.1 - 1.1e-17 64.4 0.1 1.5e-17 63.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ78088.1 - 2.1e-06 27.5 0.1 4.8e-06 26.3 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_Gly3P_dh_N PF01210.18 KNZ78088.1 - 0.0033 17.1 0.0 0.13 11.9 0.0 2.8 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short_C2 PF13561.1 KNZ78088.1 - 0.0049 16.6 0.0 0.0068 16.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KNZ78088.1 - 0.0051 16.8 0.1 0.019 14.9 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 KNZ78088.1 - 0.015 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 KNZ78088.1 - 0.046 13.1 0.0 0.63 9.4 0.0 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family YjeF_N PF03853.10 KNZ78088.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Bac_rhamnosid PF05592.6 KNZ78089.1 - 4.2e-22 78.0 0.1 6.8e-22 77.3 0.1 1.3 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KNZ78089.1 - 0.021 13.5 0.2 0.033 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF608 Methyltransf_2 PF00891.13 KNZ78092.1 - 2.6e-22 79.1 0.0 4.9e-22 78.3 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KNZ78092.1 - 0.029 14.9 0.0 0.055 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ78092.1 - 0.032 14.7 0.0 0.21 12.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Sulfolobus_pRN PF05584.6 KNZ78092.1 - 0.07 13.1 0.4 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Sulfolobus plasmid regulatory protein APH PF01636.18 KNZ78094.1 - 1.5e-07 31.4 0.1 4e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ78094.1 - 0.00038 19.6 0.0 0.00056 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 KNZ78094.1 - 0.0022 17.6 0.0 0.0045 16.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Nif11 PF07862.6 KNZ78094.1 - 0.05 13.5 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function F-box-like PF12937.2 KNZ78095.1 - 2.2e-10 40.1 0.1 4.9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ78095.1 - 0.011 15.3 0.1 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KNZ78098.1 - 2.1e-10 40.1 0.1 1.3e-09 37.6 0.1 2.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ78098.1 - 0.045 13.4 0.1 0.24 11.0 0.1 2.3 1 1 0 1 1 1 0 F-box domain LRR_6 PF13516.1 KNZ78098.1 - 5 7.5 5.1 74 3.8 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat DUF4588 PF15251.1 KNZ78099.1 - 0.0066 16.4 9.3 0.02 14.9 6.4 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) GOLD_2 PF13897.1 KNZ78099.1 - 0.014 15.6 0.2 0.025 14.7 0.1 1.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Mid2 PF04478.7 KNZ78100.1 - 0.0014 18.1 2.2 0.0032 16.9 1.5 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Yip1 PF04893.12 KNZ78100.1 - 0.0029 17.1 0.4 0.0029 17.1 0.3 1.5 2 0 0 2 2 2 1 Yip1 domain Herpes_gE PF02480.11 KNZ78100.1 - 0.0036 15.6 0.0 0.0048 15.2 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 KNZ78100.1 - 0.0037 16.7 2.7 0.0078 15.7 1.8 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.5 KNZ78100.1 - 0.0041 16.4 5.4 0.0073 15.5 3.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 KNZ78100.1 - 0.016 15.6 0.1 0.056 13.8 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 KNZ78100.1 - 0.028 14.0 2.6 0.042 13.4 0.0 2.5 2 1 0 2 2 2 0 IncA protein FlxA PF14282.1 KNZ78100.1 - 0.031 14.2 1.9 0.072 13.0 1.3 1.5 1 0 0 1 1 1 0 FlxA-like protein Syndecan PF01034.15 KNZ78100.1 - 0.064 12.9 1.4 0.13 11.9 1.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF1191 PF06697.7 KNZ78100.1 - 0.1 11.3 0.1 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) TMEM154 PF15102.1 KNZ78100.1 - 0.11 12.2 0.1 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family PDGLE PF13190.1 KNZ78100.1 - 2.1 8.0 5.3 6.3 6.5 3.4 2.0 2 1 0 2 2 2 0 PDGLE domain DUF3343 PF11823.3 KNZ78101.1 - 0.055 12.7 0.2 6.8 6.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3343) Tannase PF07519.6 KNZ78102.1 - 1.3e-102 343.9 0.0 1.6e-102 343.6 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 KNZ78102.1 - 2.9e-05 23.8 0.0 0.001 18.8 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ78102.1 - 0.0013 18.3 0.2 0.003 17.1 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KNZ78102.1 - 0.0014 18.5 0.0 0.0049 16.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ78102.1 - 0.0064 15.7 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF281 PF03436.8 KNZ78103.1 - 0.17 11.9 2.2 19 5.3 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF281) Ank_2 PF12796.2 KNZ78106.1 - 7.5e-10 39.0 0.0 1.3e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ78106.1 - 7.5e-09 34.9 0.4 0.0012 18.5 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KNZ78106.1 - 2.3e-08 34.3 0.1 0.021 15.3 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ78106.1 - 6.8e-05 22.7 0.1 0.016 15.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KNZ78106.1 - 0.00011 22.3 0.1 0.037 14.2 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) 4HBT_2 PF13279.1 KNZ78108.1 - 8.3e-07 29.4 0.0 1.4e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily BTB PF00651.26 KNZ78109.1 - 1.9e-08 34.2 0.1 5.1e-08 32.8 0.1 1.7 1 1 0 1 1 1 1 BTB/POZ domain Misat_Tub_SegII PF10644.4 KNZ78110.1 - 1.5e-32 112.0 0.0 4.8e-32 110.4 0.0 2.0 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KNZ78110.1 - 1.3e-30 106.2 0.0 2.3e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 KNZ78110.1 - 0.0062 16.3 0.0 0.34 10.7 0.0 2.3 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Gti1_Pac2 PF09729.4 KNZ78111.1 - 5.7e-27 94.6 0.8 2.2e-24 86.2 0.6 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family Pkinase_Tyr PF07714.12 KNZ78112.1 - 3.6e-50 170.4 0.0 5.3e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ78112.1 - 2.4e-41 141.6 0.0 4.8e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KNZ78112.1 - 0.00038 19.8 0.0 0.00079 18.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KNZ78112.1 - 0.0061 15.6 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ78112.1 - 0.0076 16.0 3.4 0.019 14.7 0.4 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family NPV_P10 PF05531.7 KNZ78112.1 - 0.05 13.8 1.2 0.17 12.1 0.1 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Kinase-like PF14531.1 KNZ78112.1 - 0.15 11.0 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HTH_12 PF08461.5 KNZ78113.1 - 0.092 12.4 0.1 6.1 6.6 0.0 3.2 3 0 0 3 3 3 0 Ribonuclease R winged-helix domain zf-CCHC PF00098.18 KNZ78114.1 - 0.77 9.7 3.9 0.18 11.8 0.6 1.6 2 0 0 2 2 2 0 Zinc knuckle Asp_protease_2 PF13650.1 KNZ78117.1 - 0.0011 19.4 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ78117.1 - 0.0044 16.5 0.1 0.022 14.3 0.0 1.9 1 1 1 2 2 2 1 Aspartyl protease RVP_2 PF08284.6 KNZ78118.1 - 0.00036 20.4 0.1 0.00041 20.2 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KNZ78118.1 - 0.033 14.6 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Las1 PF04031.8 KNZ78121.1 - 2.4e-43 147.4 0.2 5.3e-43 146.3 0.2 1.6 1 0 0 1 1 1 1 Las1-like DLH PF01738.13 KNZ78123.1 - 1.4e-12 47.3 0.0 1.9e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KNZ78123.1 - 0.0096 15.6 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Prenylcys_lyase PF07156.9 KNZ78124.1 - 1.3e-39 136.1 0.0 1.8e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 KNZ78124.1 - 1.4e-09 37.8 0.0 5.7e-09 35.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KNZ78124.1 - 0.00057 18.9 0.0 0.54 9.0 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KNZ78124.1 - 0.00067 18.8 0.0 0.95 8.4 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KNZ78124.1 - 0.001 18.8 0.0 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KNZ78124.1 - 0.0097 15.9 0.0 4.1 7.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Ammonium_transp PF00909.16 KNZ78125.1 - 3e-110 368.4 21.6 3.8e-110 368.0 15.0 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family SieB PF14163.1 KNZ78125.1 - 0.19 11.2 4.5 5.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Superinfection exclusion protein B DUF4231 PF14015.1 KNZ78125.1 - 1.4 8.9 6.0 0.38 10.7 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) BPL_LplA_LipB PF03099.14 KNZ78126.1 - 2.1e-06 27.7 0.0 3.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family zf-H2C2_5 PF13909.1 KNZ78126.1 - 0.063 13.5 0.3 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain NAD_binding_10 PF13460.1 KNZ78127.1 - 7.3e-05 22.8 0.0 0.00069 19.6 0.0 2.0 1 1 1 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KNZ78127.1 - 0.006 15.8 0.1 0.01 15.0 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 KNZ78127.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ATP11 PF06644.6 KNZ78128.1 - 2.9e-66 223.7 0.2 3.4e-66 223.4 0.1 1.0 1 0 0 1 1 1 1 ATP11 protein ERM PF00769.14 KNZ78128.1 - 0.0022 17.5 1.1 0.0027 17.2 0.7 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DEAD PF00270.24 KNZ78129.1 - 1.4e-42 145.1 2.0 2.6e-42 144.2 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ78129.1 - 4.9e-27 93.6 0.3 4.6e-26 90.4 0.2 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KNZ78129.1 - 5.1e-05 22.9 1.2 0.00015 21.4 0.1 2.1 1 1 1 2 2 2 1 Part of AAA domain ResIII PF04851.10 KNZ78129.1 - 0.0049 16.7 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KNZ78129.1 - 0.032 13.3 0.0 0.076 12.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 KNZ78129.1 - 0.089 12.3 0.3 0.18 11.3 0.2 1.5 1 0 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 KNZ78129.1 - 0.099 11.7 0.0 0.22 10.6 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) ISG65-75 PF11727.3 KNZ78130.1 - 0.007 15.4 11.9 0.0093 15.0 8.2 1.2 1 0 0 1 1 1 1 Invariant surface glycoprotein DUF883 PF05957.8 KNZ78130.1 - 0.01 16.2 3.7 0.01 16.2 2.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2580 PF10824.3 KNZ78130.1 - 0.017 15.4 5.4 0.027 14.8 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2580) NAF PF03822.9 KNZ78130.1 - 0.021 14.5 0.3 0.066 12.9 0.2 1.9 1 0 0 1 1 1 0 NAF domain GGDEF PF00990.16 KNZ78130.1 - 0.022 14.3 0.9 0.028 13.9 0.6 1.1 1 0 0 1 1 1 0 GGDEF domain Erythro_esteras PF05139.9 KNZ78130.1 - 0.13 11.4 6.0 0.15 11.2 4.1 1.0 1 0 0 1 1 1 0 Erythromycin esterase Phasin PF05597.6 KNZ78130.1 - 0.5 10.1 10.3 0.21 11.3 4.7 2.0 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DivIVA PF05103.8 KNZ78130.1 - 0.54 10.3 12.3 0.99 9.4 8.6 1.5 1 1 0 1 1 1 0 DivIVA protein Effector_1 PF04518.7 KNZ78130.1 - 0.55 9.1 7.4 0.67 8.8 5.1 1.2 1 0 0 1 1 1 0 Effector from type III secretion system DDHD PF02862.12 KNZ78130.1 - 0.84 9.3 8.1 0.94 9.2 5.6 1.1 1 0 0 1 1 1 0 DDHD domain DUF3619 PF12279.3 KNZ78130.1 - 0.84 9.7 5.6 1.2 9.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) DUF4449 PF14613.1 KNZ78130.1 - 2.2 8.1 11.2 2.7 7.9 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) YtxH PF12732.2 KNZ78130.1 - 3.7 7.9 17.2 13 6.2 2.3 2.9 1 1 1 2 2 2 0 YtxH-like protein Atg14 PF10186.4 KNZ78130.1 - 6.3 5.6 9.9 7.3 5.4 6.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 p450 PF00067.17 KNZ78131.1 - 4.2e-54 183.8 0.0 5.6e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KNZ78132.1 - 9.9e-63 212.2 0.0 1.3e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acatn PF13000.2 KNZ78133.1 - 2.2e-130 435.7 28.9 3.8e-63 213.8 8.3 3.4 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 TPD52 PF04201.10 KNZ78133.1 - 0.0017 18.0 0.6 0.0038 16.9 0.4 1.5 1 0 0 1 1 1 1 Tumour protein D52 family GYF PF02213.11 KNZ78134.1 - 1.1e-15 56.9 0.9 2.3e-15 55.8 0.6 1.6 1 0 0 1 1 1 1 GYF domain Siah-Interact_N PF09032.6 KNZ78135.1 - 0.69 10.0 4.3 1.8 8.6 0.5 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal Glyco_hydro_16 PF00722.16 KNZ78136.1 - 3.5e-11 42.7 0.1 1.8e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Arm PF00514.18 KNZ78137.1 - 9.5e-65 212.4 28.3 3.1e-13 49.0 0.1 10.5 9 2 2 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KNZ78137.1 - 7.4e-24 83.8 7.8 0.0054 16.9 0.0 7.1 1 1 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 KNZ78137.1 - 3.6e-18 65.4 6.0 0.011 16.1 0.2 7.5 6 1 1 7 7 7 4 HEAT-like repeat HEAT PF02985.17 KNZ78137.1 - 1.3e-16 59.1 15.1 0.011 15.7 0.0 9.2 10 0 0 10 10 10 5 HEAT repeat Arm_2 PF04826.8 KNZ78137.1 - 2.6e-10 39.8 8.7 5.4e-05 22.4 0.5 3.8 2 2 0 2 2 2 2 Armadillo-like KAP PF05804.7 KNZ78137.1 - 2.1e-07 29.2 3.2 3.4e-07 28.5 2.2 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 KNZ78137.1 - 1.1e-05 24.7 8.1 0.12 11.4 0.0 4.4 1 1 2 4 4 4 3 V-ATPase subunit H V-ATPase_H_C PF11698.3 KNZ78137.1 - 0.0014 18.5 3.2 8.2 6.3 0.0 4.4 3 1 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.11 KNZ78137.1 - 0.0038 17.5 4.8 9.3 7.0 0.4 5.6 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Abhydrolase_2 PF02230.11 KNZ78138.1 - 6.2e-19 68.2 0.0 6.9e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KNZ78138.1 - 0.00043 20.2 0.0 0.00043 20.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ78138.1 - 0.0031 17.2 0.0 0.0031 17.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PolyA_pol PF01743.15 KNZ78139.1 - 1.4e-26 93.1 0.0 2.6e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KNZ78139.1 - 2.4e-06 27.0 0.0 5.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DEAD PF00270.24 KNZ78140.1 - 2e-40 138.0 0.0 3.2e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ78140.1 - 2.8e-23 81.5 0.0 7.6e-23 80.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ78140.1 - 8.2e-07 29.0 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KNZ78140.1 - 0.012 15.3 1.2 0.032 13.9 0.5 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 KNZ78140.1 - 0.16 12.1 0.4 0.69 10.0 0.3 2.0 1 1 0 1 1 1 0 AAA domain Glyco_hydro_43 PF04616.9 KNZ78141.1 - 1.4e-18 67.0 1.6 2.1e-18 66.4 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 KNZ78141.1 - 9.6e-06 25.7 4.3 2.2e-05 24.6 3.0 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) Mito_carr PF00153.22 KNZ78142.1 - 3.7e-28 97.0 1.1 1.3e-15 56.9 0.0 3.0 3 1 0 3 3 3 2 Mitochondrial carrier protein Herpes_Helicase PF02689.9 KNZ78143.1 - 2.9e-08 31.9 0.0 3.1e-08 31.8 0.0 1.0 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 KNZ78144.1 - 5.1e-17 61.8 0.0 6.2e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 KNZ78144.1 - 0.017 14.9 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 KNZ78144.1 - 0.049 12.8 0.0 0.065 12.4 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein DRTGG PF07085.7 KNZ78144.1 - 0.058 12.9 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 DRTGG domain Y_phosphatase PF00102.22 KNZ78144.1 - 0.083 12.2 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-CCHC PF00098.18 KNZ78148.1 - 0.054 13.4 0.9 0.091 12.7 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.1 KNZ78150.1 - 0.08 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease VWA_3 PF13768.1 KNZ78151.1 - 2.3e-22 79.3 0.0 4.5e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 KNZ78151.1 - 5.1e-15 55.2 0.0 8.6e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 KNZ78151.1 - 9.1e-14 51.9 0.0 2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KNZ78151.1 - 3e-09 36.8 0.0 9.3e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KNZ78151.1 - 3.8e-05 22.9 0.0 7.9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VIT_2 PF13757.1 KNZ78151.1 - 0.00018 20.8 0.0 0.00047 19.5 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.4 KNZ78151.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus DEAD PF00270.24 KNZ78152.1 - 4.8e-36 123.7 0.1 7.6e-36 123.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ78152.1 - 2.9e-22 78.3 0.0 2.2e-21 75.4 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ78152.1 - 0.00016 21.5 0.3 0.00032 20.5 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HATPase_c PF02518.21 KNZ78153.1 - 2.9e-28 97.7 0.1 5.8e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KNZ78153.1 - 6e-17 61.6 0.0 2.4e-14 53.3 0.0 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KNZ78153.1 - 2.4e-16 59.4 0.9 1.2e-15 57.2 0.0 2.9 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 KNZ78153.1 - 7.3e-15 55.4 0.1 4.3e-14 52.9 0.1 2.4 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.20 KNZ78153.1 - 1.4e-07 30.9 0.0 2.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ78153.1 - 1.2e-05 24.5 0.0 2.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c_3 PF13589.1 KNZ78153.1 - 0.00038 20.1 0.4 0.012 15.2 0.0 2.7 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.1 KNZ78153.1 - 0.0072 16.4 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 GAF domain TPR_11 PF13414.1 KNZ78153.1 - 0.05 13.2 0.2 0.59 9.8 0.1 2.7 2 0 0 2 2 2 0 TPR repeat AAA_25 PF13481.1 KNZ78153.1 - 0.11 11.9 0.2 0.44 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 KNZ78154.1 - 2.2e-74 249.8 0.0 3.6e-74 249.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ78154.1 - 2.1e-36 125.3 0.0 5.6e-36 123.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase H2TH PF06831.9 KNZ78154.1 - 8.3e-19 67.1 0.0 1.9e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Kinase-like PF14531.1 KNZ78154.1 - 0.00079 18.4 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ78154.1 - 0.034 13.8 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Mak16 PF04874.9 KNZ78154.1 - 0.079 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Mak16 protein C-terminal region DUF605 PF04652.11 KNZ78154.1 - 2.4 7.4 11.7 3.2 7.0 8.1 1.2 1 0 0 1 1 1 0 Vta1 like Utp12 PF04003.7 KNZ78155.1 - 1.8e-13 50.3 0.2 8.5e-13 48.1 0.2 2.0 1 1 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 KNZ78155.1 - 6.9e-06 25.7 0.1 0.4 10.6 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat MFS_1 PF07690.11 KNZ78156.1 - 2.3e-48 164.7 36.0 6.8e-33 113.8 9.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KNZ78156.1 - 7.6e-05 21.2 3.3 7.6e-05 21.2 2.3 2.8 2 2 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 KNZ78156.1 - 9.2e-05 22.1 4.7 0.023 14.4 0.2 3.8 3 0 0 3 3 3 2 MFS_1 like family PUCC PF03209.10 KNZ78156.1 - 0.008 14.9 10.6 0.019 13.7 0.9 2.3 2 0 0 2 2 2 2 PUCC protein OATP PF03137.15 KNZ78156.1 - 0.0091 14.0 4.2 0.21 9.5 0.7 3.2 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 KNZ78156.1 - 2.6 6.4 24.0 0.021 13.4 6.2 3.2 2 2 0 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.11 KNZ78157.1 - 7.2e-41 140.0 36.9 9.1e-30 103.5 10.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KNZ78157.1 - 0.0002 19.9 0.8 0.0002 19.9 0.5 3.4 2 2 1 3 3 3 1 MFS/sugar transport protein PUCC PF03209.10 KNZ78157.1 - 0.0012 17.6 0.8 0.0012 17.6 0.5 2.3 2 0 0 2 2 2 1 PUCC protein Pam17 PF08566.5 KNZ78157.1 - 0.5 10.0 5.5 1.4 8.5 0.3 2.7 2 1 0 2 2 2 0 Mitochondrial import protein Pam17 OATP PF03137.15 KNZ78157.1 - 1.8 6.4 9.6 0.056 11.4 1.5 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Gly-zipper_Omp PF13488.1 KNZ78157.1 - 2 8.1 8.9 5 6.8 0.2 2.6 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.10 KNZ78157.1 - 4.3 7.0 8.5 0.46 10.1 0.2 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain Sugar_tr PF00083.19 KNZ78157.1 - 7.1 5.0 25.8 0.019 13.5 7.1 3.1 2 2 0 2 2 2 0 Sugar (and other) transporter Apolipoprotein PF01442.13 KNZ78158.1 - 0.015 14.7 1.2 3.1 7.2 0.1 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain CorA PF01544.13 KNZ78158.1 - 0.029 13.4 0.6 0.044 12.8 0.0 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein PRCC PF10253.4 KNZ78159.1 - 0.79 10.3 3.6 1.2 9.8 2.5 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF605 PF04652.11 KNZ78159.1 - 4.2 6.6 10.1 4.6 6.5 7.0 1.1 1 0 0 1 1 1 0 Vta1 like GHMP_kinases_N PF00288.21 KNZ78160.1 - 3.3e-10 39.8 0.4 6.9e-10 38.8 0.3 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KNZ78160.1 - 0.0077 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Dynein_heavy PF03028.10 KNZ78161.1 - 2.6e-179 597.6 0.1 6.7e-179 596.2 0.0 1.7 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KNZ78161.1 - 4.9e-129 430.4 8.9 4.9e-129 430.4 6.2 2.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KNZ78161.1 - 4.5e-78 261.9 0.0 3.2e-77 259.1 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KNZ78161.1 - 2.2e-44 150.9 0.0 7.4e-44 149.2 0.0 2.0 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 KNZ78161.1 - 4.3e-44 150.5 0.6 9.1e-43 146.1 0.1 2.7 2 1 0 2 2 1 1 P-loop containing dynein motor region D4 MT PF12777.2 KNZ78161.1 - 1.1e-26 93.4 11.7 2e-26 92.5 8.1 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KNZ78161.1 - 2e-23 82.6 0.0 1.3e-07 31.4 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KNZ78161.1 - 4.9e-21 75.0 0.0 1.8e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 KNZ78161.1 - 7e-15 55.3 0.3 0.015 15.4 0.0 5.8 5 0 0 5 5 5 3 AAA domain AAA PF00004.24 KNZ78161.1 - 1.8e-13 50.8 0.0 0.00085 19.5 0.0 5.1 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KNZ78161.1 - 1.4e-11 44.4 3.9 0.074 12.9 0.0 6.2 6 0 0 6 6 5 3 AAA domain AAA_17 PF13207.1 KNZ78161.1 - 1.7e-09 38.5 1.0 0.11 13.3 0.0 6.2 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.1 KNZ78161.1 - 2.7e-09 37.3 3.4 0.021 15.1 0.0 6.7 6 0 0 6 6 6 1 AAA domain AAA_16 PF13191.1 KNZ78161.1 - 1.3e-07 31.7 9.4 0.06 13.3 0.0 6.4 6 1 0 7 7 6 2 AAA ATPase domain AAA_19 PF13245.1 KNZ78161.1 - 6.1e-07 29.1 0.0 0.85 9.4 0.0 4.9 4 0 0 4 4 4 1 Part of AAA domain AAA_14 PF13173.1 KNZ78161.1 - 1.3e-06 28.3 0.0 0.6 10.0 0.0 5.0 5 0 0 5 5 4 2 AAA domain Mg_chelatase PF01078.16 KNZ78161.1 - 3.4e-06 26.3 0.4 0.48 9.5 0.0 3.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI T2SE PF00437.15 KNZ78161.1 - 3.6e-06 26.1 1.6 0.061 12.2 0.0 4.0 5 0 0 5 5 3 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KNZ78161.1 - 2.1e-05 24.1 1.0 0.97 8.8 0.0 4.3 4 0 0 4 4 3 1 FtsK/SpoIIIE family AAA_29 PF13555.1 KNZ78161.1 - 8.5e-05 22.0 0.0 0.68 9.5 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 KNZ78161.1 - 0.00018 20.9 1.3 0.35 10.2 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KNZ78161.1 - 0.0014 17.7 1.6 2.3 7.2 0.0 5.0 5 1 0 5 5 5 1 Zeta toxin AAA_25 PF13481.1 KNZ78161.1 - 0.0018 17.6 0.2 1.8 7.9 0.0 4.1 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.22 KNZ78161.1 - 0.0037 17.5 2.3 9.8 6.4 0.0 4.4 4 0 0 4 4 3 0 ABC transporter RNA_helicase PF00910.17 KNZ78161.1 - 0.0055 16.8 0.0 19 5.4 0.0 4.4 4 0 0 4 4 4 0 RNA helicase ResIII PF04851.10 KNZ78161.1 - 0.0098 15.7 0.5 2.8 7.7 0.0 4.1 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit PduV-EutP PF10662.4 KNZ78161.1 - 0.022 14.2 0.3 7.3 6.0 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 KNZ78161.1 - 0.025 14.3 0.1 24 4.6 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KNZ78161.1 - 0.048 13.0 1.5 31 3.9 0.1 3.9 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 KNZ78161.1 - 0.051 13.0 4.5 8.1 5.7 0.2 4.6 4 0 0 4 4 4 0 AAA-like domain DUF258 PF03193.11 KNZ78161.1 - 0.089 11.9 0.1 35 3.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function, DUF258 DUF418 PF04235.7 KNZ78161.1 - 0.09 12.4 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF418) ERM PF00769.14 KNZ78161.1 - 0.46 9.9 25.9 1.8 8.0 4.3 2.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family IFT46_B_C PF12317.3 KNZ78161.1 - 1.1 8.5 10.9 0.61 9.4 0.1 3.7 3 0 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal AAA_11 PF13086.1 KNZ78161.1 - 4.6 6.7 10.0 3.5 7.1 0.0 4.3 5 0 0 5 5 5 0 AAA domain LSM PF01423.17 KNZ78162.1 - 6.6e-14 51.2 0.3 1e-13 50.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain zf-C3HC4_3 PF13920.1 KNZ78163.1 - 1e-09 37.9 7.6 1.3e-09 37.5 5.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ78163.1 - 3.3e-09 36.4 11.6 4.6e-09 35.9 8.1 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KNZ78163.1 - 7.8e-09 35.0 9.5 1.1e-08 34.6 6.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ78163.1 - 8.1e-09 35.3 11.3 1.1e-08 34.9 7.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ78163.1 - 3.7e-07 29.7 9.7 5.6e-07 29.1 6.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KNZ78163.1 - 0.00015 21.5 9.7 0.00034 20.4 6.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KNZ78163.1 - 0.0005 20.1 8.8 0.0012 18.8 6.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KNZ78163.1 - 0.0016 18.2 2.1 0.0021 17.8 1.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 KNZ78163.1 - 0.0021 17.9 3.2 0.0027 17.6 2.2 1.1 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_6 PF14835.1 KNZ78163.1 - 0.0068 16.1 5.8 0.01 15.6 4.0 1.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KNZ78163.1 - 0.011 15.4 5.4 0.011 15.4 2.2 2.0 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.1 KNZ78163.1 - 0.022 14.2 4.3 0.037 13.5 3.0 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KNZ78163.1 - 0.085 12.4 8.6 0.15 11.7 6.0 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DiS_P_DiS PF06750.8 KNZ78163.1 - 0.37 10.6 3.3 0.71 9.7 2.3 1.6 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain IBR PF01485.16 KNZ78163.1 - 3.1 7.7 12.5 12 5.8 8.8 1.9 1 1 0 1 1 1 0 IBR domain zf-B_box PF00643.19 KNZ78163.1 - 7.7 6.5 8.9 4.9 7.1 3.2 2.1 2 0 0 2 2 2 0 B-box zinc finger Romo1 PF10247.4 KNZ78164.1 - 1.8e-21 76.0 7.3 2.4e-21 75.6 5.0 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_YMGG PF13441.1 KNZ78164.1 - 0.18 11.3 3.4 0.28 10.7 2.4 1.4 1 1 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.4 KNZ78164.1 - 0.34 11.0 4.9 0.54 10.4 3.4 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide CS PF04969.11 KNZ78165.1 - 1.1e-05 25.8 0.0 2.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 CS domain BC10 PF06726.7 KNZ78166.1 - 1.1e-09 38.1 10.5 2.4e-09 37.0 7.3 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 WD40 PF00400.27 KNZ78167.1 - 1.8e-35 119.5 3.5 3.6e-10 39.3 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KNZ78167.1 - 1.9e-08 32.9 0.4 0.00076 17.7 0.0 3.5 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Corona_S2 PF01601.11 KNZ78167.1 - 0.16 10.0 0.2 0.23 9.5 0.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein IncA PF04156.9 KNZ78167.1 - 1.1 8.7 7.5 1.7 8.1 5.2 1.2 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 KNZ78167.1 - 1.3 8.5 4.8 1.1 8.8 2.1 1.8 1 1 0 1 1 1 0 Septum formation initiator SprT-like PF10263.4 KNZ78168.1 - 1.8e-36 125.1 1.2 2.7e-36 124.5 0.8 1.3 1 0 0 1 1 1 1 SprT-like family Ribosomal_S14 PF00253.16 KNZ78169.1 - 1.4e-17 62.7 3.8 1.5e-17 62.6 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PUF PF00806.14 KNZ78170.1 - 1.8e-55 181.3 12.1 4.3e-08 32.1 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat 7tm_7 PF08395.7 KNZ78170.1 - 0.0018 17.3 4.0 0.0027 16.8 2.8 1.2 1 0 0 1 1 1 1 7tm Chemosensory receptor DUF260 PF03195.9 KNZ78170.1 - 0.021 15.0 0.1 0.16 12.2 0.0 2.4 2 2 1 3 3 3 0 Protein of unknown function DUF260 Atg14 PF10186.4 KNZ78171.1 - 2.1e-13 49.8 0.1 4e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KNZ78171.1 - 0.1 11.6 2.7 1 8.3 2.1 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 KNZ78171.1 - 0.25 10.9 6.2 0.39 10.2 4.3 1.3 1 0 0 1 1 1 0 IncA protein Tox-ODYAM1 PF15642.1 KNZ78171.1 - 0.49 9.0 3.8 0.74 8.4 2.6 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Diphtheria_R PF01324.14 KNZ78172.1 - 0.053 13.0 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Diphtheria toxin, R domain Cullin PF00888.17 KNZ78173.1 - 2e-08 33.2 0.0 3.8e-08 32.3 0.0 1.5 2 0 0 2 2 2 1 Cullin family PARP PF00644.15 KNZ78174.1 - 1.1e-60 204.5 2.2 1e-59 201.4 0.0 2.6 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain WGR PF05406.10 KNZ78174.1 - 9.5e-20 70.3 0.3 2.5e-19 69.0 0.2 1.7 1 0 0 1 1 1 1 WGR domain PARP_reg PF02877.9 KNZ78174.1 - 1.2e-17 63.8 0.2 5.5e-14 51.9 0.1 2.3 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase, regulatory domain PBP1_TM PF14812.1 KNZ78174.1 - 1.8 8.8 10.7 4.4 7.6 2.9 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HMG_box PF00505.14 KNZ78175.1 - 5.1e-14 52.2 0.5 8.8e-14 51.5 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KNZ78175.1 - 0.00043 20.5 0.1 0.0015 18.8 0.1 1.9 1 0 0 1 1 1 1 HMG-box domain DHO_dh PF01180.16 KNZ78176.1 - 3.6e-12 45.8 0.7 8.5e-11 41.3 0.5 2.2 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase TRAPP PF04051.11 KNZ78177.1 - 2.1e-36 124.7 0.0 2.5e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component VanZ PF04892.7 KNZ78177.1 - 0.018 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 VanZ like family Prp19_bind PF06991.6 KNZ78179.1 - 3.1e-65 220.2 31.1 3.1e-65 220.2 21.6 2.4 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain zf-CCHC PF00098.18 KNZ78179.1 - 0.25 11.3 2.5 0.69 9.9 1.8 1.7 1 1 0 1 1 1 0 Zinc knuckle NAD_binding_8 PF13450.1 KNZ78180.1 - 2.1e-12 46.8 0.0 4.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KNZ78180.1 - 0.085 12.6 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KNZ78180.1 - 0.14 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain UMP1 PF05348.6 KNZ78181.1 - 6.3e-18 64.9 0.2 8.1e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 SPRY PF00622.23 KNZ78182.1 - 2.2e-21 76.2 0.1 3.4e-21 75.6 0.1 1.3 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 KNZ78182.1 - 3.5e-21 75.4 0.0 2.3e-19 69.5 0.0 2.1 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KNZ78182.1 - 0.00012 21.7 0.7 0.00026 20.6 0.1 1.9 2 0 0 2 2 2 1 LisH GTSE1_N PF15259.1 KNZ78182.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 Ricin_B_lectin PF00652.17 KNZ78183.1 - 4.1e-07 30.0 0.0 0.3 11.1 0.0 4.2 4 0 0 4 4 4 2 Ricin-type beta-trefoil lectin domain SelR PF01641.13 KNZ78183.1 - 0.098 12.3 0.1 20 4.8 0.0 2.4 2 0 0 2 2 2 0 SelR domain LexA_DNA_bind PF01726.11 KNZ78183.1 - 0.15 11.6 0.1 0.38 10.3 0.1 1.6 1 0 0 1 1 1 0 LexA DNA binding domain Porphobil_deam PF01379.15 KNZ78184.1 - 1.3e-73 246.4 0.0 1.7e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KNZ78184.1 - 1e-15 57.5 0.5 2e-15 56.6 0.3 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain UQ_con PF00179.21 KNZ78185.1 - 5.9e-23 80.8 0.0 8e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KNZ78185.1 - 0.054 13.3 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 RWD domain Copper-fist PF00649.13 KNZ78186.1 - 9.7e-14 50.2 1.3 9.7e-14 50.2 0.9 3.7 4 1 0 4 4 4 1 Copper fist DNA binding domain Nfu_N PF08712.6 KNZ78187.1 - 3.5e-32 109.8 0.0 9.8e-32 108.4 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KNZ78187.1 - 1.2e-21 76.2 0.2 2e-21 75.5 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.4 KNZ78187.1 - 0.072 12.9 0.3 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Glyco_trans_1_4 PF13692.1 KNZ78188.1 - 3.6e-17 62.7 0.0 9.1e-17 61.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KNZ78188.1 - 4.3e-05 22.9 0.0 8.4e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KNZ78188.1 - 8.9e-05 22.6 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KNZ78188.1 - 0.00048 20.3 0.0 0.00093 19.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 SBDS_C PF09377.5 KNZ78189.1 - 3.2e-42 143.1 1.6 5.3e-42 142.4 1.1 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KNZ78189.1 - 4.3e-23 80.9 0.8 4.3e-23 80.9 0.5 1.8 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Myc_N PF01056.13 KNZ78189.1 - 0.00038 19.7 0.2 0.00056 19.1 0.1 1.3 1 0 0 1 1 1 1 Myc amino-terminal region XkdN PF08890.6 KNZ78189.1 - 0.016 14.9 0.5 0.047 13.4 0.0 2.0 2 0 0 2 2 2 0 Phage XkdN-like protein Alba PF01918.16 KNZ78189.1 - 0.11 12.1 0.3 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Alba BAR PF03114.13 KNZ78190.1 - 2.6e-36 125.2 0.1 3.8e-36 124.7 0.1 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KNZ78190.1 - 1.1e-15 56.7 0.0 1.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KNZ78190.1 - 1.8e-14 53.0 0.1 2.8e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KNZ78190.1 - 2.7e-10 39.5 0.0 4.6e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 KNZ78190.1 - 0.0056 15.9 0.1 0.011 14.9 0.1 1.5 1 0 0 1 1 1 1 Vps5 C terminal like SAP30_Sin3_bdg PF13867.1 KNZ78192.1 - 0.002 17.9 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Chorismate_synt PF01264.16 KNZ78193.1 - 1.5e-129 431.4 0.0 2e-129 431.0 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase UPF0052 PF01933.13 KNZ78194.1 - 1.7e-42 145.8 0.0 2.3e-41 142.0 0.0 2.1 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 DUF3708 PF12501.3 KNZ78195.1 - 0.98 9.2 4.0 1.2 9.0 0.5 2.2 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter CARDB PF07705.6 KNZ78196.1 - 0.066 13.2 0.1 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 CARDB ABC_tran PF00005.22 KNZ78197.1 - 1.2e-47 161.6 0.0 2.9e-24 85.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 KNZ78197.1 - 3.1e-21 75.0 4.6 3.1e-21 75.0 3.2 2.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KNZ78197.1 - 5.6e-17 62.6 9.7 0.00077 19.5 0.0 5.4 5 1 0 6 6 5 4 AAA domain SMC_N PF02463.14 KNZ78197.1 - 3.4e-08 32.9 0.2 0.0064 15.7 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KNZ78197.1 - 3.1e-07 29.8 0.0 0.02 14.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KNZ78197.1 - 5.2e-07 29.6 0.0 0.013 15.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KNZ78197.1 - 1.2e-06 27.8 0.0 0.023 13.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KNZ78197.1 - 3.8e-06 27.7 0.3 0.1 13.3 0.0 3.4 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 KNZ78197.1 - 3.8e-06 27.4 0.0 0.15 12.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 KNZ78197.1 - 2.6e-05 24.3 0.2 0.13 12.4 0.0 3.7 4 1 0 4 4 4 1 AAA domain AAA_28 PF13521.1 KNZ78197.1 - 3.7e-05 23.7 0.0 0.36 10.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 KNZ78197.1 - 7e-05 21.7 1.0 0.038 12.7 0.0 2.8 3 0 0 3 3 3 2 ArgK protein NACHT PF05729.7 KNZ78197.1 - 0.00011 21.9 0.1 0.2 11.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain MobB PF03205.9 KNZ78197.1 - 0.00022 20.9 0.1 0.32 10.6 0.1 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KNZ78197.1 - 0.00052 19.9 0.4 0.1 12.4 0.0 3.1 4 0 0 4 4 2 1 AAA domain SbcCD_C PF13558.1 KNZ78197.1 - 0.00058 19.7 0.6 0.12 12.3 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KNZ78197.1 - 0.001 18.5 0.1 2.9 7.2 0.0 3.4 3 0 0 3 3 3 1 AAA-like domain Dynamin_N PF00350.18 KNZ78197.1 - 0.0013 18.5 0.2 0.75 9.6 0.0 3.1 3 1 0 3 3 2 1 Dynamin family AAA_30 PF13604.1 KNZ78197.1 - 0.0016 18.0 0.1 0.21 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KNZ78197.1 - 0.0041 17.1 6.6 0.05 13.5 0.3 3.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 KNZ78197.1 - 0.005 17.1 4.8 2.1 8.6 0.0 4.4 5 0 0 5 5 4 1 AAA domain AAA PF00004.24 KNZ78197.1 - 0.0089 16.2 0.0 4.9 7.3 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KNZ78197.1 - 0.0091 15.4 0.1 4.6 6.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 KNZ78197.1 - 0.011 15.9 0.0 6.6 6.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.8 KNZ78197.1 - 0.013 14.4 0.0 0.38 9.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 KNZ78197.1 - 0.015 15.2 0.0 4.3 7.2 0.0 3.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KNZ78197.1 - 0.03 13.8 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 KNZ78197.1 - 0.048 13.3 0.1 12 5.6 0.0 2.6 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.13 KNZ78197.1 - 0.048 13.1 0.1 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.9 KNZ78197.1 - 0.06 13.0 0.3 5.2 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) cobW PF02492.14 KNZ78197.1 - 0.11 11.9 0.1 12 5.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 KNZ78197.1 - 0.62 10.3 17.2 1 9.6 0.1 4.5 5 0 0 5 5 5 0 AAA domain AAA_15 PF13175.1 KNZ78197.1 - 0.63 9.0 15.2 0.38 9.7 0.1 4.6 4 2 1 6 6 6 0 AAA ATPase domain DUF87 PF01935.12 KNZ78197.1 - 1.1 9.0 7.9 0.83 9.4 0.0 3.3 4 0 0 4 4 3 0 Domain of unknown function DUF87 DNA_topoisoIV PF00521.15 KNZ78198.1 - 3.5e-105 352.3 2.7 3.3e-103 345.7 1.9 2.3 1 1 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KNZ78198.1 - 9.5e-33 112.8 2.9 9.5e-33 112.8 2.0 1.8 2 0 0 2 2 2 1 DNA gyrase B Toprim PF01751.17 KNZ78198.1 - 1.3e-12 47.5 0.0 5.8e-12 45.4 0.0 2.1 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 KNZ78198.1 - 1.6e-07 31.0 0.0 4.6e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Apc3 PF12895.2 KNZ78200.1 - 0.047 13.8 3.4 1.5 9.0 0.0 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KNZ78200.1 - 0.24 11.3 3.7 12 5.9 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ArsA_ATPase PF02374.10 KNZ78201.1 - 9.9e-112 372.9 0.7 1.1e-111 372.7 0.5 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KNZ78201.1 - 1.2e-15 57.4 0.0 1.7e-15 56.9 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KNZ78201.1 - 6.5e-09 35.9 0.0 1.5e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 KNZ78201.1 - 2.7e-06 26.7 0.1 8.1e-06 25.2 0.1 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KNZ78201.1 - 5.3e-05 22.7 0.6 0.00073 19.0 0.1 2.3 1 1 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KNZ78201.1 - 0.0055 16.1 1.0 0.019 14.4 0.2 2.2 2 1 0 2 2 2 1 AAA domain MipZ PF09140.6 KNZ78201.1 - 0.0066 15.5 0.2 0.016 14.2 0.1 1.8 1 1 0 1 1 1 1 ATPase MipZ YhjQ PF06564.7 KNZ78201.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.4 1 1 0 1 1 1 0 YhjQ protein AAA_19 PF13245.1 KNZ78201.1 - 0.013 15.2 0.0 0.099 12.4 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain VirC1 PF07015.6 KNZ78201.1 - 0.016 14.3 0.3 0.039 13.0 0.1 1.8 2 1 0 2 2 2 0 VirC1 protein PhoH PF02562.11 KNZ78201.1 - 0.031 13.4 0.0 0.073 12.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.12 KNZ78201.1 - 0.038 13.3 0.0 0.08 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KNZ78201.1 - 0.13 12.4 0.7 2.1 8.5 0.2 2.8 2 2 1 3 3 3 0 RNA helicase DUF4175 PF13779.1 KNZ78202.1 - 0.67 7.5 3.7 0.76 7.4 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Fe-S_biosyn PF01521.15 KNZ78203.1 - 1.8e-20 72.9 0.0 2.2e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Chon_Sulph_att PF06566.6 KNZ78203.1 - 0.33 10.5 5.4 0.43 10.1 3.8 1.1 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain Y_phosphatase PF00102.22 KNZ78204.1 - 1.3e-56 191.5 0.1 4.1e-31 108.1 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 KNZ78204.1 - 1.8e-06 28.2 0.0 6.7e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 KNZ78204.1 - 0.0017 18.6 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 KNZ78204.1 - 0.0089 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain RRM_1 PF00076.17 KNZ78205.1 - 7.9e-13 47.8 0.0 3.5e-07 29.7 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ78205.1 - 1.3e-10 41.0 0.0 4.2e-05 23.4 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ78205.1 - 4.2e-07 29.7 0.0 0.0007 19.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3934 PF13070.1 KNZ78205.1 - 1.4 9.1 3.8 2.3 8.5 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3934) Ku PF02735.11 KNZ78206.1 - 1.6e-22 79.8 0.1 3.4e-22 78.8 0.1 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 KNZ78206.1 - 7.7e-13 48.3 0.0 1.7e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.10 KNZ78206.1 - 1.4e-10 41.0 0.0 3.8e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.1 KNZ78206.1 - 1.4e-08 35.0 0.0 3.1e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KNZ78206.1 - 1.7e-05 24.6 0.1 3.3e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain SNF2_N PF00176.18 KNZ78207.1 - 1.6e-81 273.4 0.4 3.6e-81 272.2 0.3 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KNZ78207.1 - 1.9e-22 78.9 0.3 5.6e-22 77.4 0.1 1.9 2 0 0 2 2 2 1 Bromodomain SnAC PF14619.1 KNZ78207.1 - 9.9e-15 54.4 1.3 9.9e-15 54.4 0.9 4.0 3 1 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.26 KNZ78207.1 - 9.5e-14 51.0 3.8 9.8e-14 50.9 0.0 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.8 KNZ78207.1 - 1.1e-11 44.3 8.3 5.2e-11 42.1 5.7 2.3 1 0 0 1 1 1 1 HSA QLQ PF08880.6 KNZ78207.1 - 1.7e-11 43.3 0.4 7.2e-11 41.3 0.0 2.3 2 0 0 2 2 2 1 QLQ HDA2-3 PF11496.3 KNZ78207.1 - 3.2e-05 22.8 0.9 6.5e-05 21.8 0.1 1.9 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 TPR_1 PF00515.23 KNZ78208.1 - 7.5e-46 151.9 26.0 1.9e-07 30.3 0.0 9.8 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ78208.1 - 5.7e-45 147.6 18.9 1.4e-05 24.6 0.1 9.6 9 1 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ78208.1 - 5.1e-44 147.7 17.2 7.1e-10 38.3 1.6 5.7 2 2 2 6 6 6 5 TPR repeat TPR_8 PF13181.1 KNZ78208.1 - 5e-33 110.4 11.7 0.00059 19.4 0.0 9.3 7 1 2 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ78208.1 - 7.6e-28 96.5 10.2 1.5e-05 25.5 0.0 6.2 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ78208.1 - 6.5e-26 88.3 7.1 0.00025 21.0 0.1 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ78208.1 - 7.6e-26 87.8 10.5 0.018 14.7 0.0 9.3 8 1 1 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ78208.1 - 2e-25 88.5 17.5 1.1e-07 31.6 0.0 6.7 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ78208.1 - 4.8e-24 82.6 9.0 0.00082 19.7 0.0 8.9 2 2 7 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ78208.1 - 4.2e-22 78.2 16.1 3.5e-06 27.2 0.2 6.6 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ78208.1 - 9.7e-19 66.4 10.9 0.011 16.0 0.0 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ78208.1 - 2.4e-12 46.5 9.1 0.015 15.1 0.1 5.6 3 1 4 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 KNZ78208.1 - 2.8e-12 46.5 13.2 1.7e-05 24.8 0.4 4.2 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 KNZ78208.1 - 3.5e-05 23.1 9.0 1.4 7.9 0.0 4.6 2 2 1 4 4 4 3 Soluble NSF attachment protein, SNAP TPR_15 PF13429.1 KNZ78208.1 - 5.6e-05 22.3 5.9 0.0095 15.0 0.9 3.9 1 1 2 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 KNZ78208.1 - 0.00041 20.4 0.1 0.0028 17.7 0.1 2.5 2 1 1 3 3 2 1 Tetratricopeptide repeat RPN7 PF10602.4 KNZ78208.1 - 0.0012 18.2 1.0 17 4.7 0.0 4.8 4 2 2 6 6 6 0 26S proteasome subunit RPN7 TPR_21 PF09976.4 KNZ78208.1 - 0.025 14.5 13.0 0.4 10.6 0.6 3.9 2 2 1 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.5 KNZ78208.1 - 0.079 11.7 0.0 10 4.7 0.0 2.4 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 KNZ78208.1 - 1.4 8.9 17.0 33 4.6 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Erf4 PF10256.4 KNZ78209.1 - 1.7e-26 92.3 0.1 4.3e-26 91.1 0.1 1.6 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family bZIP_1 PF00170.16 KNZ78210.1 - 1.2e-10 41.2 15.7 2.3e-10 40.2 10.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 KNZ78210.1 - 9.2e-10 38.7 0.0 9.2e-10 38.7 0.0 4.1 1 1 1 3 3 3 1 Transcription factor PAP1 bZIP_2 PF07716.10 KNZ78210.1 - 7.7e-05 22.4 14.2 7.7e-05 22.4 9.8 2.1 1 1 1 2 2 2 1 Basic region leucine zipper DivIC PF04977.10 KNZ78210.1 - 0.12 11.9 3.9 0.28 10.7 2.7 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 KNZ78210.1 - 0.21 11.9 1.5 0.52 10.6 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Glutaredoxin2_C PF04399.8 KNZ78210.1 - 0.36 10.3 2.7 0.79 9.3 1.8 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain bZIP_Maf PF03131.12 KNZ78210.1 - 8.6 6.7 13.5 2.6 8.4 6.9 1.9 1 1 1 2 2 2 0 bZIP Maf transcription factor Brr6_like_C_C PF10104.4 KNZ78211.1 - 1e-37 128.6 0.2 1.5e-37 128.1 0.2 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain CLP_protease PF00574.18 KNZ78212.1 - 5.7e-67 224.9 0.0 7.8e-67 224.4 0.0 1.2 1 0 0 1 1 1 1 Clp protease Reprolysin_5 PF13688.1 KNZ78213.1 - 8.3e-44 149.8 4.8 1.6e-43 148.9 3.3 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KNZ78213.1 - 2.6e-40 138.1 0.6 4e-40 137.5 0.4 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KNZ78213.1 - 1.3e-37 129.5 2.1 2.2e-37 128.7 1.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KNZ78213.1 - 8.5e-20 71.5 0.0 2.4e-19 70.0 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.14 KNZ78213.1 - 2e-06 27.5 7.2 3e-05 23.7 5.0 2.7 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 KNZ78213.1 - 9.3e-06 25.4 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M54 PF07998.6 KNZ78213.1 - 0.47 10.2 1.1 0.87 9.3 0.7 1.3 1 0 0 1 1 1 0 Peptidase family M54 SHS2_Rpb7-N PF03876.12 KNZ78217.1 - 1.1e-13 51.0 0.0 1.8e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KNZ78217.1 - 7.2e-12 45.2 0.6 1.5e-11 44.2 0.4 1.5 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 KNZ78217.1 - 0.0073 16.5 0.1 0.016 15.4 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 DEAD PF00270.24 KNZ78219.1 - 1.2e-41 141.9 0.0 5.2e-41 139.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ78219.1 - 5.4e-29 99.8 0.0 1.7e-27 95.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain LytR_C PF13399.1 KNZ78219.1 - 0.011 16.1 0.2 20 5.6 0.0 4.7 6 0 0 6 6 6 0 LytR cell envelope-related transcriptional attenuator CMS1 PF14617.1 KNZ78219.1 - 0.012 14.6 0.0 0.012 14.6 0.0 3.4 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Porph_ging PF09697.5 KNZ78219.1 - 0.03 14.4 0.8 0.19 11.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (Porph_ging) AAA_19 PF13245.1 KNZ78219.1 - 0.05 13.3 0.5 0.17 11.6 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain MIP-T3 PF10243.4 KNZ78219.1 - 2.6 6.3 31.8 3.9 5.8 22.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Oxysterol_BP PF01237.13 KNZ78220.1 - 2.9e-83 279.2 0.0 3.8e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein ADIP PF11559.3 KNZ78221.1 - 0.0036 17.2 10.3 0.0036 17.2 7.2 6.2 3 1 4 7 7 7 2 Afadin- and alpha -actinin-Binding PAM2 PF07145.10 KNZ78221.1 - 0.42 10.2 6.6 7.5 6.2 0.3 3.2 3 0 0 3 3 3 0 Ataxin-2 C-terminal region PBP PF01161.15 KNZ78222.1 - 2.1e-18 66.5 0.7 3.2e-18 65.9 0.5 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FYVE PF01363.16 KNZ78223.1 - 8.9e-19 67.1 3.0 1.6e-18 66.3 2.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 KNZ78223.1 - 0.0019 18.0 1.6 0.0019 18.0 1.1 1.8 2 0 0 2 2 2 1 IBR domain zf-B_box PF00643.19 KNZ78223.1 - 6.9 6.6 8.6 7.3 6.5 0.7 2.6 3 0 0 3 3 3 0 B-box zinc finger DNA_methylase PF00145.12 KNZ78224.1 - 1e-31 110.3 0.0 1.4e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_26 PF13659.1 KNZ78224.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RNase_H PF00075.19 KNZ78227.1 - 1.6e-06 28.5 0.0 1.7e-06 28.4 0.0 1.0 1 0 0 1 1 1 1 RNase H PCI PF01399.22 KNZ78228.1 - 1.2e-15 57.7 0.1 2.7e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 PCI domain Apc5 PF12862.2 KNZ78228.1 - 0.0071 16.1 0.7 0.028 14.2 0.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_8 PF13181.1 KNZ78228.1 - 0.0097 15.6 1.5 1.1 9.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ78228.1 - 0.023 14.4 9.6 13 5.8 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ78228.1 - 0.026 15.1 14.0 3.9 8.3 0.3 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat DDRGK PF09756.4 KNZ78228.1 - 0.048 13.0 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 DDRGK domain RPN7 PF10602.4 KNZ78229.1 - 8.6e-53 178.3 0.0 1.3e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KNZ78229.1 - 9.4e-18 64.4 0.4 9.4e-17 61.2 0.1 2.5 2 1 1 3 3 3 1 PCI domain TPR_15 PF13429.1 KNZ78229.1 - 0.0074 15.3 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ78229.1 - 0.058 13.3 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PIF1 PF05970.9 KNZ78232.1 - 7.8e-05 21.7 0.1 7.8e-05 21.7 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase NikR_C PF08753.6 KNZ78232.1 - 0.043 13.7 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 NikR C terminal nickel binding domain PIF1 PF05970.9 KNZ78233.1 - 1.4e-28 99.9 0.1 1.7e-28 99.6 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 KNZ78233.1 - 0.016 15.0 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KNZ78233.1 - 0.045 13.3 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 KNZ78233.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Torsin Pkinase PF00069.20 KNZ78234.1 - 1.2e-05 24.5 0.1 2.6e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KNZ78234.1 - 4.6e-05 22.5 0.1 8.4e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ78234.1 - 0.00075 19.3 0.3 0.0016 18.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 KNZ78234.1 - 0.031 13.4 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.15 KNZ78234.1 - 0.044 13.3 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PQQ_2 PF13360.1 KNZ78237.1 - 0.0022 17.4 0.0 0.017 14.6 0.0 2.2 1 1 0 1 1 1 1 PQQ-like domain WD40 PF00400.27 KNZ78237.1 - 0.0061 16.4 0.3 2.1 8.3 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat BBS1 PF14779.1 KNZ78237.1 - 0.016 14.2 0.3 2.4 7.0 0.0 3.0 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.1 KNZ78237.1 - 0.083 12.6 0.3 2.8 7.7 0.0 3.1 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Aldo_ket_red PF00248.16 KNZ78248.1 - 3.7e-49 167.0 0.0 4.7e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family E3_binding PF02817.12 KNZ78248.1 - 0.075 12.6 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 e3 binding domain Proteasome PF00227.21 KNZ78249.1 - 1.5e-32 112.4 0.0 1.8e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Rot1 PF10681.4 KNZ78250.1 - 2.2e-58 197.0 0.1 2.6e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal MutS_I PF01624.15 KNZ78251.1 - 2e-08 34.2 0.0 2.2e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 MutS domain I V4R PF02830.13 KNZ78251.1 - 0.022 14.5 0.1 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 V4R domain YgbA_NO PF11756.3 KNZ78251.1 - 0.048 13.6 0.3 0.058 13.4 0.2 1.1 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter HisG PF01634.13 KNZ78253.1 - 1e-49 168.2 0.0 1.5e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 KNZ78253.1 - 3.9e-24 84.3 0.0 9.2e-24 83.1 0.0 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 KNZ78253.1 - 8.1e-06 25.5 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Pro-kuma_activ PF09286.6 KNZ78254.1 - 1.9e-46 157.6 0.0 3.1e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KNZ78254.1 - 0.00012 21.3 0.1 0.0002 20.5 0.1 1.3 1 0 0 1 1 1 1 Subtilase family Utp12 PF04003.7 KNZ78255.1 - 0.052 13.4 0.3 5.6 6.9 0.0 2.6 2 0 0 2 2 2 0 Dip2/Utp12 Family Glycos_transf_3 PF00591.16 KNZ78256.1 - 4.2e-80 268.8 0.0 5.5e-80 268.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KNZ78256.1 - 1.3e-08 34.2 0.0 4.3e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Myotub-related PF06602.9 KNZ78257.1 - 0.0066 15.2 0.1 0.0087 14.8 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Pro-kuma_activ PF09286.6 KNZ78258.1 - 5.4e-42 143.2 0.0 8.4e-42 142.5 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KNZ78258.1 - 0.00058 19.1 0.9 0.00093 18.4 0.6 1.4 1 0 0 1 1 1 1 Subtilase family Sad1_UNC PF07738.8 KNZ78259.1 - 8e-23 80.7 0.0 1.4e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal NACHT PF05729.7 KNZ78260.1 - 0.02 14.5 0.1 0.041 13.5 0.1 1.5 1 1 0 1 1 1 0 NACHT domain C1_1 PF00130.17 KNZ78262.1 - 0.65 9.7 7.0 2.7 7.8 0.0 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NOT2_3_5 PF04153.13 KNZ78265.1 - 6.2e-34 116.7 0.9 7.8e-34 116.4 0.6 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Prenyltrans PF00432.16 KNZ78266.1 - 2.8e-27 93.9 12.2 1.2e-11 43.9 1.4 4.8 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KNZ78266.1 - 5.8e-15 55.6 0.6 6.6e-05 23.2 0.0 4.0 2 2 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KNZ78266.1 - 0.0059 16.6 0.0 1.1 9.2 0.0 3.0 3 0 0 3 3 3 1 Prenyltransferase-like Chromo PF00385.19 KNZ78267.1 - 1.8e-05 24.3 0.2 2.4e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.20 KNZ78268.1 - 2e-11 43.5 0.0 2.1e-10 40.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ78268.1 - 0.00065 18.8 0.0 0.048 12.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Seadorna_VP7 PF07387.6 KNZ78268.1 - 0.13 11.0 0.1 0.19 10.4 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Myosin_head PF00063.16 KNZ78271.1 - 2.7e-32 111.6 5.4 1.2e-20 73.2 0.7 3.1 1 1 2 3 3 3 3 Myosin head (motor domain) O-FucT PF10250.4 KNZ78271.1 - 6.3e-06 25.5 0.0 1.9e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase Metallophos PF00149.23 KNZ78275.1 - 1.3e-13 50.7 3.8 1.9e-13 50.2 2.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KNZ78275.1 - 6.5e-12 45.5 0.1 9.8e-12 44.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase_Tyr PF07714.12 KNZ78276.1 - 3.6e-42 144.2 0.0 5.7e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ78276.1 - 3.3e-41 141.1 0.0 4.7e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KNZ78276.1 - 0.00019 20.5 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ78276.1 - 0.084 12.5 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family ENTH PF01417.15 KNZ78278.1 - 1.9e-38 131.1 0.1 2.8e-38 130.5 0.1 1.3 1 0 0 1 1 1 1 ENTH domain DUF1031 PF06275.6 KNZ78278.1 - 0.12 12.4 0.1 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) GRP PF07172.6 KNZ78278.1 - 2.3 8.7 15.5 4.8 7.7 10.8 1.4 1 0 0 1 1 1 0 Glycine rich protein family cobW PF02492.14 KNZ78279.1 - 9.5e-45 152.2 0.0 1.3e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KNZ78279.1 - 6.5e-06 25.7 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 KNZ78279.1 - 5.7e-05 22.6 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KNZ78279.1 - 0.001 18.9 0.0 0.0025 17.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KNZ78279.1 - 0.0015 18.7 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KNZ78279.1 - 0.0017 18.0 0.4 0.014 15.0 0.0 2.3 2 1 1 3 3 3 1 Archaeal ATPase AAA_10 PF12846.2 KNZ78279.1 - 0.0051 16.3 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 KNZ78279.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 KNZ78279.1 - 0.02 14.6 0.0 0.057 13.1 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 KNZ78279.1 - 0.027 14.0 0.1 0.071 12.6 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 KNZ78279.1 - 0.028 14.7 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KNZ78279.1 - 0.029 13.4 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ArgK PF03308.11 KNZ78279.1 - 0.034 12.9 0.4 0.13 11.0 0.0 2.1 3 0 0 3 3 3 0 ArgK protein LpxK PF02606.9 KNZ78279.1 - 0.043 12.7 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase ABC_tran PF00005.22 KNZ78279.1 - 0.051 13.8 0.0 0.092 13.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 KNZ78279.1 - 0.064 12.4 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arf PF00025.16 KNZ78279.1 - 0.067 12.4 0.1 9.9 5.3 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Miro PF08477.8 KNZ78279.1 - 0.072 13.5 0.0 0.31 11.5 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein DSPc PF00782.15 KNZ78280.1 - 3.2e-29 101.1 0.0 4e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 KNZ78280.1 - 8.9e-05 21.5 0.0 0.0001 21.3 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 KNZ78280.1 - 0.015 15.5 0.1 0.76 10.0 0.0 2.2 1 1 1 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 KNZ78280.1 - 0.095 12.0 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase UAA PF08449.6 KNZ78281.1 - 3.7e-63 213.2 6.8 4.9e-63 212.8 4.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KNZ78281.1 - 3.7e-10 39.9 15.8 2.4e-09 37.2 5.2 2.7 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KNZ78281.1 - 0.00038 19.6 7.6 0.04 13.0 1.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 KNZ78281.1 - 0.0011 19.0 6.8 0.0011 19.0 4.7 3.5 2 2 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 KNZ78281.1 - 0.39 10.3 18.2 0.048 13.3 6.0 3.0 2 1 0 2 2 2 0 Triose-phosphate Transporter family UPF0546 PF10639.4 KNZ78281.1 - 4.7 7.0 8.2 2.8 7.7 0.3 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0546 Pkinase PF00069.20 KNZ78282.1 - 2.8e-12 46.3 0.0 2.2e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ78282.1 - 0.0048 15.9 0.0 0.18 10.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SIS PF01380.17 KNZ78283.1 - 3e-59 198.3 0.1 3.7e-33 113.9 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KNZ78283.1 - 8.5e-23 80.6 0.1 1.1e-16 60.5 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KNZ78283.1 - 8.2e-18 64.6 0.0 1.8e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KNZ78283.1 - 1.2e-12 47.7 0.0 2.6e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KNZ78283.1 - 5.3e-07 28.6 0.0 8.9e-07 27.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 KNZ78283.1 - 0.0006 19.5 0.0 0.028 14.1 0.0 2.6 2 1 1 3 3 3 1 SIS domain p450 PF00067.17 KNZ78285.1 - 8.7e-59 199.2 0.0 1.2e-58 198.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 gag-asp_proteas PF13975.1 KNZ78287.1 - 0.0012 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ78287.1 - 0.0044 17.4 0.0 0.0078 16.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease XH PF03469.9 KNZ78288.1 - 0.044 13.4 0.8 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 XH domain Asp_protease_2 PF13650.1 KNZ78290.1 - 0.00012 22.5 0.0 0.00032 21.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease NSP10 PF09401.5 KNZ78290.1 - 0.042 13.5 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA synthesis protein NSP10 SPT2 PF08243.6 KNZ78291.1 - 1.3 9.3 7.2 2.9 8.2 5.0 1.5 1 0 0 1 1 1 0 SPT2 chromatin protein DUF667 PF05018.8 KNZ78293.1 - 1.6e-10 40.4 0.0 2.6e-05 23.5 0.0 3.3 3 1 0 3 3 3 3 Protein of unknown function (DUF667) Con-6 PF10346.4 KNZ78297.1 - 2.1e-28 97.4 2.8 2.5e-15 55.5 0.3 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 KNZ78297.1 - 0.0039 16.7 1.2 0.055 12.9 0.1 2.2 1 1 0 2 2 2 1 SpoIIIAH-like protein MutS_V PF00488.16 KNZ78299.1 - 7e-76 254.7 0.0 1.2e-75 253.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KNZ78299.1 - 4.9e-44 150.5 1.2 8.4e-44 149.8 0.8 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KNZ78299.1 - 3.2e-27 94.7 0.3 3.3e-23 81.8 0.0 2.5 2 0 0 2 2 2 2 MutS domain I MutS_II PF05188.12 KNZ78299.1 - 1.4e-11 44.5 0.0 4.7e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KNZ78299.1 - 0.00036 20.6 0.5 0.00094 19.3 0.4 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 KNZ78299.1 - 0.011 15.2 0.1 0.033 13.7 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KNZ78299.1 - 0.12 12.6 0.2 0.12 12.6 0.1 2.6 2 0 0 2 2 2 0 ABC transporter Methyltransf_16 PF10294.4 KNZ78300.1 - 3.7e-12 46.0 0.0 7.8e-12 44.9 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KNZ78300.1 - 0.0014 19.1 0.0 0.0021 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ78300.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain RecA PF00154.16 KNZ78301.1 - 0.00011 21.4 0.1 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.6 KNZ78301.1 - 0.0002 20.3 0.5 0.0013 17.7 0.0 2.0 1 1 1 2 2 2 1 Rad51 KaiC PF06745.8 KNZ78301.1 - 0.0014 17.8 0.0 0.0027 16.8 0.0 1.5 1 0 0 1 1 1 1 KaiC IstB_IS21 PF01695.12 KNZ78301.1 - 0.0046 16.3 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein PAXNEB PF05625.6 KNZ78301.1 - 0.013 14.3 0.3 0.02 13.7 0.2 1.3 1 0 0 1 1 1 0 PAXNEB protein Rhabdo_matrix PF03397.9 KNZ78301.1 - 0.014 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Rhabdovirus matrix protein TIP49 PF06068.8 KNZ78301.1 - 0.057 12.1 0.0 0.086 11.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus DnaB_C PF03796.10 KNZ78301.1 - 0.095 11.5 0.1 0.17 10.7 0.0 1.6 2 1 0 2 2 2 0 DnaB-like helicase C terminal domain DUF2316 PF10078.4 KNZ78301.1 - 0.12 12.3 0.1 0.41 10.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Abhydrolase_6 PF12697.2 KNZ78302.1 - 1.2e-21 77.6 0.0 1.6e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ78302.1 - 8.7e-12 45.0 0.0 2.6e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ78302.1 - 2.8e-10 40.1 0.0 3.8e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ78302.1 - 0.0068 15.6 0.0 0.0096 15.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KNZ78302.1 - 0.016 14.5 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Ndr PF03096.9 KNZ78302.1 - 0.068 11.6 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Ndr family 5-FTHF_cyc-lig PF01812.15 KNZ78303.1 - 5.9e-43 146.8 0.0 6.5e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family PIG-P PF08510.7 KNZ78304.1 - 7.7e-27 93.4 12.9 3.6e-25 88.0 8.9 2.0 1 1 0 1 1 1 1 PIG-P DPM2 PF07297.7 KNZ78304.1 - 1.6 9.0 5.9 2.9 8.2 4.1 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) zf-C2H2 PF00096.21 KNZ78305.1 - 8.5e-12 44.6 8.7 5.4e-07 29.5 0.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ78305.1 - 1.8e-08 34.1 5.6 0.0001 22.3 0.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KNZ78305.1 - 1.4e-06 28.2 8.2 0.0017 18.5 0.3 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KNZ78305.1 - 1.4e-05 25.1 1.6 0.0019 18.2 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KNZ78305.1 - 0.00053 20.0 1.8 0.011 15.9 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KNZ78305.1 - 0.015 15.4 3.9 0.17 12.2 0.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.10 KNZ78305.1 - 0.57 9.9 4.1 3.7 7.3 0.2 2.7 3 0 0 3 3 3 0 BED zinc finger TP2 PF01254.13 KNZ78305.1 - 0.68 10.2 5.2 0.38 11.1 2.2 1.5 1 1 0 1 1 1 0 Nuclear transition protein 2 XPG_I PF00867.13 KNZ78306.1 - 9.8e-26 89.6 0.1 2.2e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KNZ78306.1 - 5.4e-23 81.1 0.0 1.1e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KNZ78306.1 - 1.4e-08 34.5 0.1 2.2e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 KNZ78306.1 - 0.0037 17.4 0.0 0.011 15.9 0.0 1.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold TPR_2 PF07719.12 KNZ78306.1 - 0.056 13.3 0.2 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HHH_5 PF14520.1 KNZ78306.1 - 0.069 13.3 0.1 0.69 10.1 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain Aldo_ket_red PF00248.16 KNZ78307.1 - 6.6e-29 100.6 0.0 4.9e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family HCMVantigenic_N PF12154.3 KNZ78309.1 - 0.024 14.5 2.0 0.09 12.6 1.4 2.0 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV Y_phosphatase2 PF03162.8 KNZ78309.1 - 0.087 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Herpes_DNAp_acc PF04929.7 KNZ78309.1 - 1.6 7.5 5.4 6.5 5.6 3.8 1.7 1 1 0 1 1 1 0 Herpes DNA replication accessory factor NAC PF01849.13 KNZ78310.1 - 3.5e-22 77.6 0.1 5.5e-22 77.0 0.1 1.3 1 0 0 1 1 1 1 NAC domain Acetyltransf_1 PF00583.19 KNZ78311.1 - 1.6e-12 47.2 0.0 2.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KNZ78311.1 - 3.2e-05 23.9 0.0 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNZ78311.1 - 7.8e-05 22.7 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KNZ78311.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 KNZ78311.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cofilin_ADF PF00241.15 KNZ78312.1 - 1.2e-18 67.2 0.4 1.5e-18 66.8 0.3 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein OstA_2 PF13100.1 KNZ78312.1 - 0.017 14.4 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 OstA-like protein Neugrin PF06413.6 KNZ78313.1 - 9.9e-14 51.6 0.8 1.3e-13 51.2 0.6 1.1 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 KNZ78313.1 - 3e-06 27.2 7.0 4.7e-06 26.6 4.9 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 p450 PF00067.17 KNZ78314.1 - 6.4e-33 113.9 0.0 1.7e-32 112.6 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 HlyIII PF03006.15 KNZ78315.1 - 5.9e-19 68.3 3.3 7.1e-19 68.0 2.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related CLTH PF10607.4 KNZ78316.1 - 1.2e-33 115.8 0.3 2.3e-33 114.9 0.2 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KNZ78316.1 - 0.00025 20.6 0.1 0.001 18.7 0.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger Orthopox_A5L PF06193.6 KNZ78316.1 - 0.13 12.1 0.3 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Inhibitor_I36 PF03995.8 KNZ78318.1 - 3 8.2 5.8 21 5.5 4.0 1.9 1 1 0 1 1 1 0 Peptidase inhibitor family I36 PIG-S PF10510.4 KNZ78319.1 - 5.2e-100 335.5 1.3 6.2e-100 335.3 0.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Myb_DNA-binding PF00249.26 KNZ78320.1 - 3.5e-17 62.2 0.0 4e-07 29.9 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KNZ78320.1 - 5.3e-10 39.2 0.0 0.0019 18.2 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Gp-FAR-1 PF05823.7 KNZ78320.1 - 0.041 13.8 0.1 0.19 11.6 0.1 2.0 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) MogR_DNAbind PF12181.3 KNZ78320.1 - 0.078 12.7 0.3 2.4 7.9 0.2 2.2 2 0 0 2 2 2 0 DNA binding domain of the motility gene repressor (MogR) Neur_chan_memb PF02932.11 KNZ78320.1 - 0.21 11.4 5.5 0.064 13.1 0.8 2.4 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Rotamase_3 PF13616.1 KNZ78321.1 - 3e-19 69.4 0.1 4e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 KNZ78321.1 - 4.4e-19 68.9 0.0 7.2e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KNZ78321.1 - 1.1e-06 29.2 0.0 1.4e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain M_domain PF12938.2 KNZ78321.1 - 0.072 12.8 0.7 0.088 12.6 0.5 1.2 1 0 0 1 1 1 0 M domain of GW182 ABC_tran PF00005.22 KNZ78322.1 - 3.1e-31 108.5 0.2 9.4e-17 61.5 0.0 3.1 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 KNZ78322.1 - 1.5e-14 53.2 5.5 3.5e-14 52.0 3.8 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 KNZ78322.1 - 3.9e-13 50.0 5.4 0.006 16.5 0.0 4.4 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 KNZ78322.1 - 2.4e-11 43.2 5.3 0.00026 20.2 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 KNZ78322.1 - 7.1e-07 28.5 3.1 7.1e-07 28.5 2.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.1 KNZ78322.1 - 6.9e-06 26.2 0.0 0.0067 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 KNZ78322.1 - 1.3e-05 24.4 1.0 0.71 8.8 0.0 4.5 3 2 2 5 5 5 1 AAA ATPase domain DUF258 PF03193.11 KNZ78322.1 - 1.9e-05 23.9 1.5 0.14 11.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 Miro PF08477.8 KNZ78322.1 - 2.7e-05 24.6 1.0 0.037 14.5 0.0 3.2 3 1 0 3 3 2 1 Miro-like protein AAA PF00004.24 KNZ78322.1 - 6.5e-05 23.1 0.0 0.16 12.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KNZ78322.1 - 9.4e-05 21.8 0.4 0.13 11.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 KNZ78322.1 - 0.00014 21.7 0.0 0.092 12.6 0.0 3.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 KNZ78322.1 - 0.00014 21.7 0.1 0.026 14.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KNZ78322.1 - 0.00016 22.5 0.8 1.1 10.1 0.2 3.5 2 2 0 2 2 2 1 AAA domain NACHT PF05729.7 KNZ78322.1 - 0.00027 20.6 0.8 0.041 13.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Fer4_6 PF12837.2 KNZ78322.1 - 0.00051 19.7 1.6 0.00051 19.7 1.1 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_18 PF13238.1 KNZ78322.1 - 0.0011 19.2 0.0 1.6 9.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain VirE PF05272.6 KNZ78322.1 - 0.0018 17.7 0.0 0.99 8.8 0.0 2.5 2 0 0 2 2 2 1 Virulence-associated protein E AAA_16 PF13191.1 KNZ78322.1 - 0.0018 18.2 0.5 0.42 10.5 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Fer4_2 PF12797.2 KNZ78322.1 - 0.0019 18.0 1.4 0.0019 18.0 1.0 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.2 KNZ78322.1 - 0.0022 18.3 1.8 0.0022 18.3 1.3 2.4 1 1 2 3 3 3 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 KNZ78322.1 - 0.0023 17.7 11.5 0.0046 16.7 8.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KNZ78322.1 - 0.0032 17.2 0.9 0.0032 17.2 0.6 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain RNA_helicase PF00910.17 KNZ78322.1 - 0.0056 16.8 0.2 1.9 8.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase UPF0079 PF02367.12 KNZ78322.1 - 0.0063 16.1 0.9 0.094 12.3 0.0 2.7 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 KNZ78322.1 - 0.0094 15.3 0.2 3.7 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KNZ78322.1 - 0.01 15.2 2.1 0.77 9.1 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_16 PF13484.1 KNZ78322.1 - 0.011 16.3 0.1 0.011 16.3 0.1 2.6 2 1 1 3 3 1 0 4Fe-4S double cluster binding domain AAA_28 PF13521.1 KNZ78322.1 - 0.013 15.4 0.3 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_3 PF12798.2 KNZ78322.1 - 0.016 15.7 4.3 0.016 15.7 3.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_14 PF13173.1 KNZ78322.1 - 0.025 14.5 1.2 5.5 6.8 0.0 3.2 2 2 1 3 3 2 0 AAA domain NB-ARC PF00931.17 KNZ78322.1 - 0.028 13.2 0.0 0.88 8.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Fer4_9 PF13187.1 KNZ78322.1 - 0.031 14.5 12.6 0.1 12.8 8.7 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_24 PF13479.1 KNZ78322.1 - 0.035 13.6 0.5 0.66 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KNZ78322.1 - 0.036 13.7 0.8 0.75 9.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) MobB PF03205.9 KNZ78322.1 - 0.041 13.5 1.4 5.6 6.6 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 KNZ78322.1 - 0.059 12.0 0.0 1.1 7.8 0.0 2.7 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein AAA_13 PF13166.1 KNZ78322.1 - 0.11 10.9 1.2 0.53 8.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain HflK_N PF12221.3 KNZ78322.1 - 0.13 12.0 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial membrane protein N terminal PduV-EutP PF10662.4 KNZ78322.1 - 0.17 11.3 1.0 0.66 9.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_8 PF13183.1 KNZ78322.1 - 0.23 11.5 9.5 0.094 12.7 0.7 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_23 PF13476.1 KNZ78322.1 - 0.41 10.9 7.6 0.35 11.1 0.2 2.6 2 1 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 KNZ78322.1 - 0.66 10.4 13.1 0.087 13.2 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.1 KNZ78322.1 - 2.2 8.9 7.4 0.25 11.9 0.7 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain LIM PF00412.17 KNZ78323.1 - 9.8e-08 31.9 13.4 2.9e-05 24.0 0.6 3.0 2 1 0 2 2 2 2 LIM domain Nucleoplasmin PF03066.10 KNZ78323.1 - 0.076 12.5 3.2 0.17 11.3 2.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin Mak16 PF04874.9 KNZ78323.1 - 0.47 10.5 10.6 1 9.5 7.4 1.5 1 0 0 1 1 1 0 Mak16 protein C-terminal region Sigma70_ner PF04546.8 KNZ78323.1 - 3.2 7.3 8.0 5.9 6.4 5.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region TRAP_alpha PF03896.11 KNZ78323.1 - 4.2 6.2 5.4 6.9 5.5 3.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Mob1_phocein PF03637.12 KNZ78324.1 - 4.1e-61 205.6 0.2 5.1e-61 205.3 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family WW PF00397.21 KNZ78327.1 - 2.4 8.0 6.4 7.2 6.5 0.1 2.7 2 0 0 2 2 2 0 WW domain UbiA PF01040.13 KNZ78327.1 - 3.2 6.9 10.2 9.3 5.3 1.1 2.1 1 1 1 2 2 2 0 UbiA prenyltransferase family XPG_I PF00867.13 KNZ78328.1 - 1.4e-17 63.5 0.0 2.8e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KNZ78328.1 - 2.3e-05 24.5 0.0 4.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KNZ78328.1 - 0.041 14.1 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DUF737 PF05300.6 KNZ78329.1 - 0.013 15.4 0.1 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Pol_alpha_B_N PF08418.5 KNZ78329.1 - 0.015 14.8 4.7 0.02 14.4 3.3 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Coatomer_WDAD PF04053.9 KNZ78330.1 - 1.4e-139 465.7 0.0 3.1e-139 464.6 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 KNZ78330.1 - 3.1e-99 332.3 0.0 4.2e-99 331.9 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KNZ78330.1 - 3.6e-59 194.6 8.8 1.4e-10 40.6 0.1 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat TPR_2 PF07719.12 KNZ78330.1 - 0.006 16.4 1.6 0.31 11.0 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Nup160 PF11715.3 KNZ78330.1 - 0.014 13.5 5.0 0.68 8.0 0.0 3.7 1 1 2 4 4 4 0 Nucleoporin Nup120/160 TPR_14 PF13428.1 KNZ78330.1 - 0.028 15.0 6.0 21 6.0 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ78330.1 - 0.11 12.0 1.7 2.9 7.6 0.1 3.1 3 0 0 3 3 3 0 TPR repeat PspA_IM30 PF04012.7 KNZ78330.1 - 0.13 11.6 0.6 0.28 10.4 0.4 1.5 1 0 0 1 1 1 0 PspA/IM30 family 2-Hacid_dh_C PF02826.14 KNZ78331.1 - 1.2e-40 138.5 0.0 1.7e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KNZ78331.1 - 5.3e-22 77.7 0.0 6.3e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KNZ78331.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KNZ78331.1 - 0.099 13.0 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Flavoprotein PF02441.14 KNZ78333.1 - 1.9e-41 140.7 0.1 3.3e-41 139.9 0.0 1.4 2 0 0 2 2 2 1 Flavoprotein NDUFA12 PF05071.11 KNZ78334.1 - 0.0015 18.9 1.8 0.0015 18.9 1.2 2.0 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PTRF_SDPR PF15237.1 KNZ78334.1 - 0.0048 16.3 0.1 0.0056 16.1 0.0 1.0 1 0 0 1 1 1 1 PTRF/SDPR family tRNA_NucTran2_2 PF13735.1 KNZ78334.1 - 0.0063 16.3 0.7 0.008 16.0 0.5 1.1 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative DUF572 PF04502.8 KNZ78334.1 - 0.068 12.3 1.8 0.079 12.1 1.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PCI PF01399.22 KNZ78335.1 - 1.6e-21 76.5 1.9 2.6e-21 75.8 0.0 2.3 3 1 0 3 3 3 1 PCI domain Rpn3_C PF08375.6 KNZ78335.1 - 5.7e-19 68.2 0.1 5.7e-19 68.2 0.0 2.3 3 0 0 3 3 3 1 Proteasome regulatory subunit C-terminal OKR_DC_1_C PF03711.10 KNZ78335.1 - 0.0078 16.2 0.1 0.24 11.4 0.0 2.8 3 0 0 3 3 3 1 Orn/Lys/Arg decarboxylase, C-terminal domain TPR_2 PF07719.12 KNZ78335.1 - 0.12 12.3 3.6 0.18 11.7 1.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ78335.1 - 0.37 10.7 6.2 1.1 9.3 2.3 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat Herpes_Helicase PF02689.9 KNZ78337.1 - 3.9e-08 31.5 0.0 4.1e-08 31.4 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ78337.1 - 0.018 15.2 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Ank_3 PF13606.1 KNZ78338.1 - 3e-08 33.1 0.7 0.00013 21.8 0.1 2.5 1 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KNZ78338.1 - 5.7e-07 29.7 0.0 9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ78338.1 - 1.9e-06 27.4 0.4 0.0003 20.4 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KNZ78338.1 - 6.2e-06 26.2 0.3 0.00027 21.0 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KNZ78338.1 - 0.014 15.9 0.5 0.033 14.7 0.3 1.7 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ssu72 PF04722.8 KNZ78338.1 - 0.036 13.3 2.0 0.06 12.6 1.4 1.5 1 1 0 1 1 1 0 Ssu72-like protein ENTH PF01417.15 KNZ78339.1 - 3.2e-31 107.8 2.0 4.7e-31 107.2 1.4 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KNZ78339.1 - 0.017 13.8 0.4 0.027 13.1 0.0 1.5 2 0 0 2 2 2 0 ANTH domain UIM PF02809.15 KNZ78339.1 - 0.092 12.3 0.9 0.092 12.3 0.6 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif Sec2p PF06428.6 KNZ78339.1 - 0.54 10.1 6.8 0.099 12.5 1.2 2.3 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Cys_Met_Meta_PP PF01053.15 KNZ78341.1 - 2.8e-21 75.2 0.1 4.1e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Yeast_MT PF11403.3 KNZ78341.1 - 0.9 9.7 4.5 2 8.5 3.1 1.5 1 0 0 1 1 1 0 Yeast metallothionein PIF1 PF05970.9 KNZ78342.1 - 5.1e-06 25.6 0.0 6.5e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Clc-like PF07062.7 KNZ78342.1 - 0.4 9.9 3.2 0.64 9.2 0.8 2.0 1 1 1 2 2 2 0 Clc-like Glyco_hydro_47 PF01532.15 KNZ78343.1 - 8.5e-107 357.5 0.0 8.2e-71 238.9 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Ribophorin_II PF05817.9 KNZ78344.1 - 7.5e-32 110.3 0.0 8.9e-32 110.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Skp1_POZ PF03931.10 KNZ78345.1 - 0.0002 21.4 0.1 0.00035 20.5 0.0 1.5 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Glyco_hydro_47 PF01532.15 KNZ78347.1 - 1e-116 390.3 0.0 1.2e-116 390.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2673 PF10880.3 KNZ78347.1 - 0.081 12.9 0.8 5.6 7.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) Glyco_hydro_47 PF01532.15 KNZ78348.1 - 3.3e-123 411.6 0.0 3.9e-123 411.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Fer2_2 PF01799.15 KNZ78349.1 - 0.034 14.0 0.0 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 [2Fe-2S] binding domain Sec20 PF03908.8 KNZ78350.1 - 4.9e-18 64.6 2.8 1.7e-17 62.8 1.9 2.0 1 0 0 1 1 1 1 Sec20 Baculo_11_kDa PF06143.6 KNZ78350.1 - 0.081 12.3 0.1 0.22 10.9 0.1 1.8 1 0 0 1 1 1 0 Baculovirus 11 kDa family COG2 PF06148.6 KNZ78350.1 - 0.33 10.8 4.4 2.3 8.1 0.1 2.4 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RRM_1 PF00076.17 KNZ78351.1 - 3.3e-52 174.0 0.0 7.4e-17 60.7 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ78351.1 - 9.8e-39 131.1 0.0 9.8e-13 47.8 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ78351.1 - 9.2e-14 51.0 0.0 0.0041 16.9 0.0 5.0 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Afaf PF15339.1 KNZ78351.1 - 0.67 9.5 5.8 4.3 6.8 0.0 3.3 3 0 0 3 3 3 0 Acrosome formation-associated factor Syntaxin-6_N PF09177.6 KNZ78352.1 - 2.8e-20 72.5 1.2 2.8e-20 72.5 0.8 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KNZ78352.1 - 9.1e-13 47.6 4.2 3.8e-12 45.7 2.9 2.1 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 KNZ78352.1 - 2.2e-05 24.0 1.2 3.5e-05 23.3 0.2 1.5 1 1 1 2 2 2 1 Membrane fusion protein Use1 TPR_MLP1_2 PF07926.7 KNZ78352.1 - 0.0009 18.9 1.1 2.6 7.7 0.0 3.0 1 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein Tail_P2_I PF09684.5 KNZ78352.1 - 0.0084 15.6 0.1 0.032 13.7 0.0 1.9 2 2 0 2 2 2 1 Phage tail protein (Tail_P2_I) DUF3040 PF11239.3 KNZ78352.1 - 0.0099 15.9 0.1 0.02 14.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) TBPIP PF07106.8 KNZ78352.1 - 0.084 12.4 4.4 0.37 10.3 0.2 2.4 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 KNZ78352.1 - 0.18 11.7 2.9 0.79 9.7 0.2 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.6 KNZ78352.1 - 0.2 11.5 1.6 10 6.0 0.1 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.3 KNZ78352.1 - 0.21 8.8 8.8 1.3 6.2 6.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Snapin_Pallidin PF14712.1 KNZ78352.1 - 0.36 11.1 6.2 3.1 8.1 0.3 2.7 2 1 0 2 2 2 0 Snapin/Pallidin SlyX PF04102.7 KNZ78352.1 - 0.44 10.9 8.5 49 4.3 0.1 4.1 3 2 1 4 4 4 0 SlyX TMF_DNA_bd PF12329.3 KNZ78352.1 - 0.46 10.3 5.3 2.3 8.0 0.3 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 KNZ78352.1 - 0.56 10.0 3.3 5.1 6.9 0.3 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hpt PF01627.18 KNZ78352.1 - 0.76 9.8 8.1 13 5.9 0.1 3.8 3 1 1 4 4 4 0 Hpt domain DUF641 PF04859.7 KNZ78352.1 - 0.9 9.2 6.6 2.5 7.8 0.2 2.9 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) DivIC PF04977.10 KNZ78352.1 - 2.1 7.9 5.1 2.1 7.8 0.5 2.9 2 1 1 3 3 3 0 Septum formation initiator Lebercilin PF15619.1 KNZ78352.1 - 5.9 6.2 8.3 1.2 8.5 0.6 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.4 KNZ78352.1 - 9.2 6.1 8.9 2 8.2 0.2 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Chromo PF00385.19 KNZ78353.1 - 3.6e-07 29.7 0.0 7.9e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 KNZ78353.1 - 0.0019 17.8 0.1 0.0043 16.7 0.1 1.6 1 0 0 1 1 1 1 PHD-finger Phage_GPO PF05929.6 KNZ78353.1 - 0.03 13.5 3.0 0.057 12.6 2.1 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase AAA_13 PF13166.1 KNZ78353.1 - 0.067 11.6 1.6 0.11 10.9 1.1 1.2 1 0 0 1 1 1 0 AAA domain DUF16 PF01519.11 KNZ78353.1 - 0.23 11.6 1.9 0.54 10.5 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF4142 PF13628.1 KNZ78353.1 - 2.1 8.3 9.5 0.35 10.8 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) FMO-like PF00743.14 KNZ78355.1 - 1.2e-43 149.0 0.0 7.6e-32 110.2 0.0 2.5 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KNZ78355.1 - 7.1e-20 71.9 0.0 1.4e-19 70.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNZ78355.1 - 2.3e-10 40.4 1.9 0.002 17.9 0.0 4.2 3 1 1 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 KNZ78355.1 - 6e-07 28.7 0.1 6.1e-05 22.0 0.0 2.9 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KNZ78355.1 - 6.1e-05 22.9 0.0 0.0008 19.3 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ78355.1 - 0.0001 22.2 0.2 0.00082 19.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KNZ78355.1 - 0.00039 19.6 0.2 0.38 9.7 0.0 3.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase DAO PF01266.19 KNZ78355.1 - 0.0026 16.7 0.1 5.1 5.9 0.0 3.4 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KNZ78355.1 - 0.031 14.5 0.2 3.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.12 KNZ78355.1 - 0.046 12.7 0.1 0.39 9.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 KNZ78355.1 - 0.16 12.3 0.2 28 5.1 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KNZ78355.1 - 0.25 10.3 1.5 6.4 5.7 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain Plant_vir_prot PF01307.12 KNZ78356.1 - 0.031 13.9 0.1 0.16 11.7 0.1 2.2 1 1 0 1 1 1 0 Plant viral movement protein Methyltransf_31 PF13847.1 KNZ78357.1 - 9.7e-19 67.4 0.0 1.8e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Sterol_MT_C PF08498.5 KNZ78357.1 - 4.8e-18 64.8 0.0 1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KNZ78357.1 - 6.4e-17 61.8 0.0 1.5e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ78357.1 - 9.9e-15 54.6 0.0 3e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 KNZ78357.1 - 1.2e-13 50.7 0.1 2.6e-13 49.7 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KNZ78357.1 - 2e-12 47.6 0.0 5.9e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ78357.1 - 2e-11 44.2 0.0 8.2e-11 42.2 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ78357.1 - 4.4e-11 42.8 0.0 1.2e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ78357.1 - 1.2e-10 41.6 0.0 2.5e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNZ78357.1 - 1.1e-06 27.9 0.0 1.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.5 KNZ78357.1 - 1.6e-05 24.4 0.1 2.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.12 KNZ78357.1 - 8.8e-05 21.6 0.0 0.00015 20.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 KNZ78357.1 - 0.00017 21.0 0.0 0.00033 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KNZ78357.1 - 0.00027 20.5 0.0 0.00046 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 KNZ78357.1 - 0.0026 17.1 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 KNZ78357.1 - 0.0035 18.1 0.0 0.015 16.0 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain UPF0020 PF01170.13 KNZ78357.1 - 0.0036 16.8 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.13 KNZ78357.1 - 0.0092 15.1 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Met_10 PF02475.11 KNZ78357.1 - 0.032 13.8 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein FGE-sulfatase PF03781.11 KNZ78358.1 - 1.7e-23 83.3 0.8 5.5e-21 75.0 0.5 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KNZ78358.1 - 8.2e-07 29.4 0.4 1.9e-06 28.2 0.3 1.6 1 0 0 1 1 1 1 DinB superfamily CASP_C PF08172.7 KNZ78358.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 CASP C terminal MFS_1 PF07690.11 KNZ78359.1 - 6.6e-22 77.6 25.2 6.6e-22 77.6 17.5 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Cupin_1 PF00190.17 KNZ78360.1 - 4.6e-19 68.2 0.0 3.5e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KNZ78360.1 - 4.8e-16 58.0 4.0 1.1e-11 44.0 0.6 2.7 2 1 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KNZ78360.1 - 2.2e-05 23.7 0.1 0.027 13.8 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 KNZ78360.1 - 0.00022 20.8 0.0 0.00094 18.8 0.0 1.8 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase GPI PF06560.6 KNZ78360.1 - 0.0021 17.0 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) Cupin_4 PF08007.7 KNZ78360.1 - 0.0083 15.4 0.0 2.6 7.2 0.0 2.1 2 0 0 2 2 2 2 Cupin superfamily protein Cupin_8 PF13621.1 KNZ78360.1 - 0.018 14.5 0.1 6.3 6.2 0.0 2.4 2 1 0 2 2 2 0 Cupin-like domain NdhN PF11909.3 KNZ78360.1 - 0.11 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N CENP-C_C PF11699.3 KNZ78360.1 - 0.14 12.1 0.0 8.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Mif2/CENP-C like AraC_binding PF02311.14 KNZ78360.1 - 0.16 11.6 0.3 3 7.5 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain Mad3_BUB1_I PF08311.7 KNZ78361.1 - 6e-25 87.4 0.0 9.9e-25 86.7 0.0 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Herpes_capsid PF06112.6 KNZ78361.1 - 0.32 11.0 10.1 0.89 9.5 7.0 1.8 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RRM_1 PF00076.17 KNZ78362.1 - 1.1e-25 88.9 0.0 6.5e-17 60.9 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ78362.1 - 4.9e-14 52.0 0.1 6.1e-11 42.1 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ78362.1 - 1.5e-09 37.5 0.0 9.4e-09 34.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KNZ78362.1 - 4.7e-07 29.3 0.1 4.8e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 KNZ78362.1 - 0.05 13.3 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNase_H PF00075.19 KNZ78364.1 - 0.001 19.3 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 RNase H Zn_Tnp_IS1595 PF12760.2 KNZ78365.1 - 0.00049 19.8 1.5 0.00063 19.4 0.1 1.9 2 1 0 2 2 2 1 Transposase zinc-ribbon domain zf-RVT PF13966.1 KNZ78365.1 - 0.0067 16.7 4.7 0.041 14.1 0.8 2.2 1 1 1 2 2 2 1 zinc-binding in reverse transcriptase TF_Zn_Ribbon PF08271.7 KNZ78365.1 - 0.057 12.7 0.2 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding MtN3_slv PF03083.11 KNZ78365.1 - 0.11 12.4 0.1 0.19 11.5 0.0 1.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF2834 PF11196.3 KNZ78368.1 - 0.001 19.2 14.2 0.0029 17.7 1.0 4.0 4 1 0 4 4 4 3 Protein of unknown function (DUF2834) Glyco_hydro_61 PF03443.9 KNZ78369.1 - 4.3e-67 226.1 0.6 6.8e-67 225.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KNZ78369.1 - 1.6e-13 50.0 6.3 1.6e-13 50.0 4.4 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Syndecan PF01034.15 KNZ78371.1 - 0.041 13.5 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Ras PF00071.17 KNZ78372.1 - 1.7e-37 128.3 0.0 3.7e-35 120.6 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KNZ78372.1 - 4.5e-16 59.4 0.0 9e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ78372.1 - 2.3e-07 30.1 0.0 6.7e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KNZ78372.1 - 1.1e-05 24.6 0.0 1.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KNZ78372.1 - 0.00071 19.0 0.0 0.0041 16.5 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KNZ78372.1 - 0.0023 17.8 0.0 0.0064 16.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KNZ78372.1 - 0.034 14.2 0.0 0.13 12.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KNZ78372.1 - 0.093 12.2 0.5 0.39 10.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain Peptidase_S10 PF00450.17 KNZ78375.1 - 9.5e-84 281.9 0.0 1.2e-83 281.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase YbgS PF13985.1 KNZ78377.1 - 0.064 13.1 1.5 0.098 12.5 1.1 1.3 1 0 0 1 1 1 0 YbgS-like protein UbiA PF01040.13 KNZ78379.1 - 1.8e-18 66.6 5.8 2.3e-18 66.3 4.0 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Abhydrolase_6 PF12697.2 KNZ78380.1 - 9.8e-13 48.4 0.1 6.4e-12 45.8 0.1 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ78380.1 - 1.4e-09 37.8 0.0 2.7e-06 27.2 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KNZ78380.1 - 0.092 12.1 0.1 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF563 PF04577.9 KNZ78380.1 - 0.13 12.1 0.0 19 5.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF563) PigN PF04987.9 KNZ78381.1 - 2e-86 290.3 36.2 2.7e-86 289.9 25.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KNZ78381.1 - 3e-12 46.5 0.0 4.1e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KNZ78381.1 - 1.4e-05 24.4 0.0 3.3e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 KNZ78381.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily p450 PF00067.17 KNZ78385.1 - 2.4e-61 207.6 0.0 3.4e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DIOX_N PF14226.1 KNZ78386.1 - 3.4e-16 59.8 0.0 5.3e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KNZ78386.1 - 4e-12 46.2 0.0 6.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 KNZ78387.1 - 4e-36 124.5 0.0 1.1e-35 123.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 DUF3294 PF07957.6 KNZ78388.1 - 0.051 13.1 0.0 0.051 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) RVP_2 PF08284.6 KNZ78389.1 - 0.0014 18.5 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Exonuc_V_gamma PF04257.9 KNZ78389.1 - 0.15 10.0 0.0 0.16 9.9 0.0 1.0 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit NAD_binding_4 PF07993.7 KNZ78390.1 - 5e-27 94.4 0.0 1e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KNZ78390.1 - 1.2e-23 83.1 0.0 8.7e-21 73.7 0.0 2.6 2 1 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 KNZ78390.1 - 8.1e-10 38.5 0.0 1.8e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ78390.1 - 0.0051 16.8 0.0 0.35 10.8 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 KNZ78390.1 - 0.017 15.0 0.0 0.44 10.4 0.0 2.5 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 KNZ78390.1 - 0.26 10.1 0.0 4.5 6.0 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Rrn6 PF10214.4 KNZ78391.1 - 5.1e-12 44.7 2.5 7e-08 31.0 0.0 3.1 3 0 0 3 3 3 3 RNA polymerase I-specific transcription-initiation factor TMEM154 PF15102.1 KNZ78392.1 - 0.0095 15.6 3.2 0.012 15.3 0.2 2.1 2 0 0 2 2 2 1 TMEM154 protein family Rax2 PF12768.2 KNZ78392.1 - 0.01 15.0 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF4448 PF14610.1 KNZ78392.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Herpes_gE PF02480.11 KNZ78392.1 - 0.02 13.1 0.1 0.029 12.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF912 PF06024.7 KNZ78392.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SKG6 PF08693.5 KNZ78392.1 - 2.6 7.4 8.4 0.045 13.0 0.7 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Mito_carr PF00153.22 KNZ78393.1 - 1.2e-46 156.3 1.6 3.9e-16 58.5 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Cpn60_TCP1 PF00118.19 KNZ78394.1 - 5.6e-136 453.9 11.2 6.4e-136 453.7 7.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3599 PF12206.3 KNZ78394.1 - 0.1 12.8 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) UFD1 PF03152.9 KNZ78395.1 - 1.8e-66 222.5 0.0 2.4e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 NMT PF01233.14 KNZ78396.1 - 4.7e-72 240.8 0.1 7e-72 240.3 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 KNZ78396.1 - 6.4e-67 224.6 0.0 1.7e-66 223.2 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 KNZ78396.1 - 5.8e-05 22.9 0.0 0.00085 19.1 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KNZ78396.1 - 0.029 14.5 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ78396.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HSP20 PF00011.16 KNZ78397.1 - 1.4e-22 79.4 0.1 1.8e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 KNZ78397.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 CS domain DUF4097 PF13349.1 KNZ78397.1 - 0.12 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) ING PF12998.2 KNZ78398.1 - 5.6e-17 61.9 0.4 8.6e-17 61.3 0.3 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KNZ78398.1 - 2.6e-09 36.6 8.3 3.9e-09 36.0 5.8 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KNZ78398.1 - 0.16 11.2 2.7 0.29 10.4 1.9 1.4 1 0 0 1 1 1 0 PHD-finger OGG_N PF07934.7 KNZ78399.1 - 6.5e-32 109.9 0.1 1e-31 109.2 0.1 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KNZ78399.1 - 3.1e-15 56.3 0.0 5.3e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein ORF6C PF10552.4 KNZ78399.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 ORF6C domain HHH PF00633.18 KNZ78399.1 - 0.14 11.8 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif NPR2 PF06218.6 KNZ78400.1 - 8.2e-79 265.2 0.0 9.3e-59 199.2 0.0 3.2 1 1 1 2 2 2 2 Nitrogen permease regulator 2 UBACT PF02134.16 KNZ78401.1 - 1e-24 85.8 0.6 2.4e-24 84.7 0.4 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein ThiF PF00899.16 KNZ78401.1 - 5.3e-23 81.3 0.0 2e-22 79.4 0.0 1.8 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 KNZ78401.1 - 1.4e-22 79.2 2.0 2.2e-22 78.6 1.4 1.3 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 KNZ78401.1 - 9.1e-18 63.3 1.4 2e-17 62.2 1.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 KNZ78401.1 - 0.0019 17.7 0.6 0.017 14.6 0.0 2.2 2 0 0 2 2 2 1 MoeZ/MoeB domain UBA_e1_C PF09358.5 KNZ78401.1 - 0.039 14.1 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain HypA PF01155.14 KNZ78401.1 - 0.087 12.5 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family RTC PF01137.16 KNZ78402.1 - 8.6e-68 227.5 0.0 9.9e-68 227.3 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KNZ78402.1 - 7.3e-28 96.5 0.0 1.3e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Sirohm_synth_C PF14823.1 KNZ78403.1 - 4.5e-17 61.1 0.0 7.7e-17 60.3 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KNZ78403.1 - 6.7e-15 53.7 0.1 1.2e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.1 KNZ78403.1 - 9.3e-12 45.1 0.1 4.9e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding zf-CCCH PF00642.19 KNZ78404.1 - 0.0026 17.4 2.3 0.0076 15.9 1.6 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 KNZ78404.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ78404.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ78404.1 - 0.16 12.0 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FYVE PF01363.16 KNZ78404.1 - 0.55 10.1 5.1 2 8.3 3.6 1.9 1 1 0 1 1 1 0 FYVE zinc finger Sulf_transp PF04143.9 KNZ78405.1 - 2.5e-13 49.8 25.4 3e-11 43.1 3.2 4.3 4 1 0 4 4 4 2 Sulphur transport DUF4341 PF14241.1 KNZ78405.1 - 9.1e-10 38.0 4.7 9.1e-10 38.0 3.3 3.3 4 1 0 4 4 4 1 Domain of unknown function (DUF4341) LEA_2 PF03168.8 KNZ78406.1 - 8.1e-06 26.1 0.2 1.5e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.7 KNZ78406.1 - 0.07 12.3 0.3 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) TSC22 PF01166.13 KNZ78407.1 - 0.002 18.0 0.2 0.0038 17.1 0.1 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF972 PF06156.8 KNZ78407.1 - 0.022 15.0 0.5 0.044 14.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) HALZ PF02183.13 KNZ78407.1 - 0.028 14.1 3.8 0.048 13.3 2.7 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper Atg14 PF10186.4 KNZ78407.1 - 0.031 13.2 0.4 0.049 12.5 0.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3186 PF11382.3 KNZ78407.1 - 0.042 12.9 0.5 0.067 12.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) bZIP_1 PF00170.16 KNZ78407.1 - 0.047 13.6 3.8 0.083 12.8 2.6 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF904 PF06005.7 KNZ78407.1 - 0.1 12.8 2.8 0.21 11.9 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) JmjC PF02373.17 KNZ78408.1 - 4.8e-15 55.7 0.1 1.2e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.6 KNZ78408.1 - 0.041 12.8 0.2 0.26 10.3 0.0 2.1 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) Pkinase PF00069.20 KNZ78410.1 - 8.2e-36 123.4 0.0 1e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ78410.1 - 5.8e-13 48.5 0.0 7.8e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ78410.1 - 0.00093 18.9 0.0 0.52 9.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pyr_redox_3 PF13738.1 KNZ78411.1 - 2.8e-22 79.7 0.0 6e-22 78.6 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KNZ78411.1 - 3.4e-12 45.3 0.6 3.5e-10 38.7 0.4 2.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KNZ78411.1 - 3.3e-11 43.0 0.0 1e-10 41.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KNZ78411.1 - 3.8e-11 42.5 0.1 5.4e-10 38.7 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KNZ78411.1 - 1.2e-08 35.1 0.0 1.4e-07 31.6 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KNZ78411.1 - 7.9e-06 25.0 0.1 1.7e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 KNZ78411.1 - 0.00064 18.7 0.6 0.0063 15.4 0.2 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KNZ78411.1 - 0.00087 19.0 0.0 0.0039 16.9 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KNZ78411.1 - 0.0015 17.4 0.0 0.0026 16.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KNZ78411.1 - 0.0045 16.1 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KNZ78411.1 - 0.013 14.3 1.0 0.28 10.0 0.3 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 KNZ78411.1 - 0.15 11.0 0.2 0.32 10.0 0.2 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Vac_ImportDeg PF09783.4 KNZ78412.1 - 1.4e-53 180.9 0.0 4.2e-52 176.1 0.0 2.0 2 0 0 2 2 2 2 Vacuolar import and degradation protein MFS_1 PF07690.11 KNZ78413.1 - 4.8e-45 153.7 51.3 2.5e-44 151.4 35.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KNZ78413.1 - 5.4e-16 57.9 15.8 7.7e-16 57.4 11.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KNZ78413.1 - 4.8e-14 51.7 11.1 4.8e-14 51.7 7.7 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter ATG22 PF11700.3 KNZ78413.1 - 9.4e-05 21.0 17.4 0.0034 15.9 0.2 3.3 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like DUF3353 PF11833.3 KNZ78413.1 - 0.38 10.1 3.7 1.9 7.8 2.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Ras PF00071.17 KNZ78414.1 - 2.4e-50 170.0 0.1 6.5e-50 168.6 0.0 1.6 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KNZ78414.1 - 2.7e-16 60.1 0.0 4.5e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ78414.1 - 2.7e-10 39.7 0.0 3.6e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KNZ78414.1 - 0.0004 19.5 0.0 0.00057 19.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KNZ78414.1 - 0.00096 17.9 0.9 0.18 10.4 0.0 2.7 2 1 1 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.17 KNZ78414.1 - 0.027 14.6 0.1 0.23 11.6 0.1 2.2 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 KNZ78414.1 - 0.032 13.5 0.1 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 KNZ78414.1 - 0.065 13.3 0.1 0.14 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KNZ78414.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain FRG1 PF06229.7 KNZ78416.1 - 1.6e-29 102.7 0.0 2.9e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 KNZ78416.1 - 0.0016 18.5 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 Fascin domain KOW PF00467.24 KNZ78417.1 - 1.9e-09 36.8 3.5 1.9e-09 36.8 2.4 1.8 2 0 0 2 2 2 1 KOW motif Cut12 PF11500.3 KNZ78417.1 - 0.055 13.1 0.3 0.055 13.1 0.2 1.5 2 0 0 2 2 2 0 Spindle pole body formation-associated protein ATP-synt_D PF01813.12 KNZ78418.1 - 3.9e-65 219.0 5.0 4.7e-65 218.8 3.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit D XAP5 PF04921.9 KNZ78419.1 - 6.8e-95 317.1 4.7 6.8e-95 317.1 3.3 2.1 2 0 0 2 2 2 1 XAP5, circadian clock regulator CTNNB1_binding PF08347.6 KNZ78419.1 - 6.3 6.9 9.4 0.33 11.1 2.0 2.0 1 1 0 2 2 2 0 N-terminal CTNNB1 binding Ribosomal_S13 PF00416.17 KNZ78420.1 - 6.3e-22 78.0 0.0 9.8e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KNZ78420.1 - 0.019 13.5 0.0 0.021 13.3 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) IMS_HHH PF11798.3 KNZ78420.1 - 0.046 13.7 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 0 IMS family HHH motif TRAPP PF04051.11 KNZ78421.1 - 6.3e-34 116.6 0.0 8.7e-34 116.2 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component C_GCAxxG_C_C PF09719.5 KNZ78421.1 - 0.051 13.3 0.0 0.71 9.6 0.0 2.1 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) WBS_methylT PF12589.3 KNZ78422.1 - 5.9e-20 71.5 11.3 9.3e-20 70.9 7.8 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KNZ78422.1 - 3.8e-09 36.9 0.0 7.6e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ78422.1 - 1.2e-06 28.3 0.0 1.8e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ78422.1 - 4.9e-05 22.9 0.0 8.1e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ78422.1 - 8.3e-05 22.9 0.0 0.00025 21.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ78422.1 - 0.00065 20.2 0.0 0.00097 19.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ78422.1 - 0.0089 16.3 0.0 0.014 15.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 KNZ78422.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase BCS1_N PF08740.6 KNZ78423.1 - 1.7e-50 171.2 2.0 2.3e-50 170.8 1.4 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KNZ78423.1 - 3.4e-19 69.3 0.0 6e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KNZ78423.1 - 4.8e-05 24.1 0.0 0.00012 22.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KNZ78423.1 - 0.00016 21.1 0.0 0.00041 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KNZ78423.1 - 0.00041 20.2 0.0 0.00094 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KNZ78423.1 - 0.00051 20.3 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ78423.1 - 0.0017 18.3 0.1 0.0054 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 KNZ78423.1 - 0.0034 17.0 0.3 0.017 14.8 0.0 2.4 3 1 0 3 3 1 1 Part of AAA domain AAA_22 PF13401.1 KNZ78423.1 - 0.0048 17.0 0.0 0.014 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KNZ78423.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KNZ78423.1 - 0.025 14.8 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KNZ78423.1 - 0.031 13.7 0.0 0.075 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KNZ78423.1 - 0.043 12.9 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 KNZ78423.1 - 0.044 13.9 0.0 0.08 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 KNZ78423.1 - 0.057 13.1 0.0 0.16 11.6 0.0 1.8 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 KNZ78423.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 KNZ78423.1 - 0.067 13.0 0.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KNZ78423.1 - 0.072 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 KNZ78423.1 - 0.072 12.7 0.0 0.88 9.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 KNZ78423.1 - 0.074 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 KNZ78423.1 - 0.081 13.2 0.0 0.18 12.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.13 KNZ78423.1 - 0.087 12.3 0.1 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Ank_2 PF12796.2 KNZ78424.1 - 3.8e-16 59.1 0.0 1.6e-08 34.7 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNZ78424.1 - 1.2e-10 41.6 0.1 6e-09 36.1 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 KNZ78424.1 - 2.4e-09 36.5 0.0 0.00033 20.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat DnaJ PF00226.26 KNZ78424.1 - 5e-08 32.5 0.2 2.5e-07 30.3 0.2 2.2 1 1 0 1 1 1 1 DnaJ domain Ank_3 PF13606.1 KNZ78424.1 - 9.4e-08 31.5 0.1 0.042 14.0 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KNZ78424.1 - 1.9e-07 31.1 0.1 0.00036 20.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) API5 PF05918.6 KNZ78424.1 - 0.018 13.5 2.7 0.034 12.6 1.9 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) LUC7 PF03194.10 KNZ78425.1 - 7.5e-72 241.8 4.0 9.5e-72 241.5 2.7 1.1 1 0 0 1 1 1 1 LUC7 N_terminus Atg14 PF10186.4 KNZ78425.1 - 0.0038 16.2 1.2 0.0062 15.5 0.9 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 KNZ78425.1 - 0.05 13.2 1.6 0.12 12.0 1.1 1.6 1 0 0 1 1 1 0 Mnd1 family DUF4510 PF14971.1 KNZ78425.1 - 0.06 13.5 4.0 1.1 9.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) Ada3 PF10198.4 KNZ78425.1 - 0.17 11.6 4.5 0.049 13.3 0.8 1.7 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 RXT2_N PF08595.6 KNZ78426.1 - 0.09 12.5 0.6 0.2 11.4 0.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal UCH PF00443.24 KNZ78427.1 - 1e-37 129.7 3.8 3.1e-37 128.1 2.7 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNZ78427.1 - 1.7e-17 63.7 5.0 7.4e-17 61.7 3.5 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KNZ78427.1 - 5e-07 29.0 0.1 1.3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.7 KNZ78427.1 - 0.001 19.4 0.0 0.026 14.9 0.0 2.9 2 0 0 2 2 2 1 DUSP domain PDE8 PF08629.5 KNZ78427.1 - 0.02 14.6 0.4 0.078 12.7 0.3 2.0 1 0 0 1 1 1 0 PDE8 phosphodiesterase zf-FPG_IleRS PF06827.9 KNZ78427.1 - 0.086 12.4 5.4 1.3 8.7 0.0 3.7 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Gaa1 PF04114.9 KNZ78428.1 - 7.1e-75 252.6 1.6 1.6e-74 251.4 1.1 1.6 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component TAFII55_N PF04658.8 KNZ78429.1 - 1.7e-51 173.9 0.4 2.9e-51 173.2 0.3 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region Tom37_C PF11801.3 KNZ78430.1 - 1.6e-15 57.3 0.0 2.3e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 KNZ78430.1 - 1.4e-06 28.4 0.0 4.1e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein Pec_lyase_C PF00544.14 KNZ78431.1 - 0.0006 19.3 7.3 0.0006 19.3 5.0 1.6 1 1 0 1 1 1 1 Pectate lyase Exo_endo_phos PF03372.18 KNZ78433.1 - 4.8e-22 79.1 0.1 6.2e-22 78.7 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KNZ78433.1 - 1.8e-05 24.3 0.0 4.8e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase OTU PF02338.14 KNZ78434.1 - 0.0041 17.7 0.0 0.0086 16.6 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease ABC_tran PF00005.22 KNZ78435.1 - 3.3e-32 111.6 1.7 4.3e-22 78.8 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 KNZ78435.1 - 6.8e-12 45.0 0.5 3.2e-05 23.2 0.0 3.5 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KNZ78435.1 - 1e-10 42.0 0.6 0.0001 22.3 0.0 3.2 3 0 0 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 KNZ78435.1 - 6e-06 26.0 2.7 6e-06 26.0 1.9 2.2 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 KNZ78435.1 - 0.0026 17.2 0.1 0.0064 15.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KNZ78435.1 - 0.0065 16.4 0.1 0.0065 16.4 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain Not3 PF04065.10 KNZ78435.1 - 0.0076 15.5 1.2 0.02 14.1 0.8 1.7 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component SbcCD_C PF13558.1 KNZ78435.1 - 0.011 15.5 0.0 0.19 11.6 0.0 2.9 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KNZ78435.1 - 6.3 7.0 6.4 1.9 8.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 KNZ78436.1 - 4.8e-21 75.5 0.0 6.5e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 KNZ78436.1 - 5e-06 26.1 0.6 1.5e-05 24.6 0.0 2.0 2 1 0 2 2 2 1 Part of AAA domain SMC_N PF02463.14 KNZ78436.1 - 3.5e-05 23.1 0.0 0.018 14.2 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KNZ78436.1 - 0.00017 21.6 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain UPF0079 PF02367.12 KNZ78436.1 - 0.00019 21.0 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 KNZ78436.1 - 0.00019 21.4 0.5 0.00045 20.2 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KNZ78436.1 - 0.00033 20.1 0.0 0.00067 19.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 KNZ78436.1 - 0.00035 20.2 0.1 0.00074 19.2 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.1 KNZ78436.1 - 0.00046 19.8 0.0 0.0014 18.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KNZ78436.1 - 0.00073 19.9 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 KNZ78436.1 - 0.0019 18.0 0.1 0.016 15.0 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KNZ78436.1 - 0.002 18.2 0.0 0.0051 16.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KNZ78436.1 - 0.0041 16.6 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain T2SE PF00437.15 KNZ78436.1 - 0.0068 15.3 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF258 PF03193.11 KNZ78436.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 KNZ78436.1 - 0.016 14.9 0.1 0.083 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KNZ78436.1 - 0.022 13.6 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_15 PF13175.1 KNZ78436.1 - 0.024 13.7 0.0 0.051 12.6 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain PIF1 PF05970.9 KNZ78436.1 - 0.026 13.4 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_33 PF13671.1 KNZ78436.1 - 0.028 14.3 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KNZ78436.1 - 0.034 14.9 0.2 0.19 12.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 KNZ78436.1 - 0.037 12.9 0.1 5.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.24 KNZ78436.1 - 0.089 12.9 0.0 0.95 9.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KNZ78436.1 - 0.089 12.4 0.1 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 KNZ78436.1 - 0.094 12.1 0.1 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 KNZ78436.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase PhoH PF02562.11 KNZ78436.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Pox_A32 PF04665.7 KNZ78436.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein PduV-EutP PF10662.4 KNZ78436.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 KNZ78436.1 - 0.15 12.3 0.1 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Snf7 PF03357.16 KNZ78437.1 - 1.6e-11 43.8 5.3 2.5e-11 43.2 3.7 1.2 1 0 0 1 1 1 1 Snf7 IncA PF04156.9 KNZ78437.1 - 0.0023 17.5 1.0 0.0023 17.5 0.7 2.0 2 0 0 2 2 2 1 IncA protein DUF812 PF05667.6 KNZ78437.1 - 0.0024 16.4 1.2 0.0037 15.8 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) COG2 PF06148.6 KNZ78437.1 - 0.02 14.7 0.4 0.02 14.7 0.3 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.7 KNZ78437.1 - 0.66 10.2 4.7 2.6 8.3 0.1 3.3 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 KNZ78437.1 - 4.5 7.3 7.1 1.8 8.6 0.4 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Herpes_gE PF02480.11 KNZ78438.1 - 0.021 13.1 0.0 0.024 12.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 KNZ78438.1 - 0.024 13.9 1.0 0.048 12.9 0.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2668 PF10873.3 KNZ78438.1 - 0.033 14.3 0.4 0.057 13.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) MGC-24 PF05283.6 KNZ78438.1 - 0.14 11.9 0.2 0.14 11.9 0.2 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Ribosomal_L30_N PF08079.7 KNZ78439.1 - 3.9e-27 94.0 17.2 7.9e-27 93.0 11.9 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KNZ78439.1 - 4.7e-19 67.7 1.0 1.2e-18 66.4 0.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Pro_CA PF00484.14 KNZ78440.1 - 1.6e-35 122.3 0.0 6.3e-18 65.2 0.0 2.1 2 0 0 2 2 2 2 Carbonic anhydrase Exo_endo_phos PF03372.18 KNZ78441.1 - 1.5e-16 61.0 0.1 2e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family bZIP_1 PF00170.16 KNZ78442.1 - 0.11 12.4 4.8 0.064 13.2 1.7 1.8 2 0 0 2 2 2 0 bZIP transcription factor SKIP_SNW PF02731.10 KNZ78443.1 - 6.4e-67 223.9 1.5 6.4e-67 223.9 1.0 1.9 2 0 0 2 2 2 1 SKIP/SNW domain Tim54 PF11711.3 KNZ78444.1 - 1.2e-72 244.6 0.0 2.7e-72 243.4 0.0 1.5 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Sec63 PF02889.11 KNZ78445.1 - 1.4e-26 93.5 0.0 7.8e-21 74.5 0.0 2.3 1 1 1 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KNZ78445.1 - 6.4e-18 64.8 0.0 1.5e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ78445.1 - 5.3e-08 32.6 0.0 1.5e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ78445.1 - 6e-05 22.9 2.1 7.3e-05 22.6 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CKS PF01111.14 KNZ78446.1 - 3.1e-36 123.0 0.2 4e-36 122.6 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Peptidase_M16 PF00675.15 KNZ78447.1 - 3.3e-38 130.7 0.5 1.5e-37 128.6 0.3 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KNZ78447.1 - 1.8e-20 73.3 0.0 6.5e-11 42.2 0.0 3.4 3 0 0 3 3 3 2 Peptidase M16 inactive domain Baculo_LEF-11 PF06385.7 KNZ78447.1 - 0.023 14.7 1.0 0.69 10.0 0.1 2.6 2 0 0 2 2 2 0 Baculovirus LEF-11 protein ATP-synt_ab PF00006.20 KNZ78448.1 - 6.7e-63 212.0 0.0 1.1e-62 211.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KNZ78448.1 - 4.5e-25 88.3 1.0 8.3e-25 87.4 0.7 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KNZ78448.1 - 5.5e-23 80.9 1.5 1.4e-22 79.6 1.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.17 KNZ78448.1 - 0.0056 15.5 0.9 0.028 13.2 0.1 2.1 2 0 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 KNZ78448.1 - 0.018 14.7 0.0 0.049 13.3 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 KNZ78448.1 - 0.022 14.4 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 KNZ78448.1 - 0.028 14.5 0.1 0.33 11.1 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KNZ78448.1 - 0.03 13.7 0.0 0.083 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KNZ78448.1 - 0.04 13.0 0.1 0.072 12.2 0.1 1.4 1 0 0 1 1 1 0 KaiC MobB PF03205.9 KNZ78448.1 - 0.043 13.5 0.2 1.8 8.2 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KNZ78448.1 - 0.043 13.9 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KNZ78448.1 - 0.047 12.8 0.1 0.084 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KNZ78448.1 - 0.049 13.6 0.1 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Med2 PF11214.3 KNZ78448.1 - 0.099 12.6 0.1 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Mediator complex subunit 2 WD40 PF00400.27 KNZ78449.1 - 3.8e-83 270.6 13.0 1.3e-13 50.2 0.0 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KNZ78449.1 - 4.3e-10 38.3 9.6 0.0032 15.6 0.1 5.7 1 1 2 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KNZ78449.1 - 2.6e-08 33.0 0.7 0.0067 15.2 0.1 4.1 1 1 3 4 4 4 4 Nup133 N terminal like eIF2A PF08662.6 KNZ78449.1 - 5.2e-05 23.0 0.2 0.053 13.2 0.1 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KNZ78449.1 - 0.00054 18.3 0.2 0.071 11.4 0.0 2.8 2 1 1 3 3 3 2 Cytochrome D1 heme domain bZIP_2 PF07716.10 KNZ78449.1 - 0.11 12.3 0.6 0.21 11.4 0.4 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Zn_clus PF00172.13 KNZ78450.1 - 7.3e-10 38.5 12.1 1.1e-09 38.0 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ins_P5_2-kin PF06090.7 KNZ78451.1 - 1.1e-42 146.1 0.0 1.6e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Acyl-CoA_dh_1 PF00441.19 KNZ78451.1 - 9.6e-40 136.1 0.2 1.8e-39 135.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KNZ78451.1 - 4.3e-30 104.6 0.0 9.5e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KNZ78451.1 - 2e-14 52.8 0.1 5.1e-14 51.5 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KNZ78451.1 - 8.3e-13 48.7 0.0 1.5e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DASH_Dad3 PF08656.5 KNZ78453.1 - 2e-19 69.0 0.1 2.4e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 WD40 PF00400.27 KNZ78454.1 - 3.9e-23 80.4 12.3 4.3e-07 29.5 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 KNZ78454.1 - 0.0011 18.2 0.6 0.0028 16.8 0.0 2.0 3 0 0 3 3 3 1 Cortical protein marker for cell polarity DPPIV_N PF00930.16 KNZ78454.1 - 0.0013 17.4 1.9 0.014 13.9 0.2 2.9 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.6 KNZ78454.1 - 0.0068 16.1 0.2 0.54 9.9 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KNZ78454.1 - 0.01 15.4 0.3 4.8 6.9 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat GATA PF00320.22 KNZ78455.1 - 2.9e-13 48.9 6.3 5.1e-13 48.1 4.4 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_9 PF13426.1 KNZ78455.1 - 0.023 15.0 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS PF00989.19 KNZ78455.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 PAS fold PAS_3 PF08447.6 KNZ78455.1 - 0.077 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 PAS fold adh_short_C2 PF13561.1 KNZ78456.1 - 4.6e-27 95.3 0.1 6e-27 94.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KNZ78456.1 - 4.9e-23 81.8 0.2 9e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ78456.1 - 2.7e-08 33.7 0.0 2.1e-07 30.7 0.0 1.9 1 1 1 2 2 2 1 KR domain Kinesin PF00225.18 KNZ78457.1 - 1.7e-101 339.3 1.2 8e-101 337.0 0.0 2.8 2 0 0 2 2 2 1 Kinesin motor domain SlyX PF04102.7 KNZ78457.1 - 0.0011 19.2 1.3 0.0011 19.2 0.9 14.7 13 6 5 19 19 19 5 SlyX DUF641 PF04859.7 KNZ78457.1 - 0.0036 17.0 2.1 0.0036 17.0 1.5 12.4 7 5 8 17 17 17 2 Plant protein of unknown function (DUF641) Arginase PF00491.16 KNZ78458.1 - 1.8e-66 224.2 0.1 2.4e-66 223.9 0.1 1.0 1 0 0 1 1 1 1 Arginase family Aminotran_1_2 PF00155.16 KNZ78459.1 - 1.4e-23 83.4 0.0 1.6e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CwfJ_C_1 PF04677.10 KNZ78460.1 - 7.2e-29 99.9 0.0 1.1e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KNZ78460.1 - 1.4e-18 67.1 0.0 2.5e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.1 KNZ78460.1 - 8.3e-11 41.1 18.4 8.9e-05 21.8 2.0 3.6 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC PF00098.18 KNZ78460.1 - 9e-06 25.3 17.4 0.00029 20.6 0.3 4.0 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_3 PF13917.1 KNZ78460.1 - 0.11 12.2 5.1 2.5 7.8 0.1 2.9 1 1 2 3 3 3 0 Zinc knuckle eIF3g PF12353.3 KNZ78460.1 - 0.14 12.0 12.1 1.5 8.7 0.5 3.1 1 1 2 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G C1_3 PF07649.7 KNZ78460.1 - 0.77 9.8 6.6 16 5.6 0.1 3.4 3 0 0 3 3 3 0 C1-like domain zf-CCHC_4 PF14392.1 KNZ78460.1 - 2.9 7.6 12.5 1.4 8.6 0.5 3.5 3 0 0 3 3 3 0 Zinc knuckle COesterase PF00135.23 KNZ78461.1 - 1.9e-57 195.1 0.0 8.2e-57 193.1 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ78461.1 - 4.1e-13 49.3 0.0 6.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 KNZ78461.1 - 0.00037 20.2 2.1 0.0028 17.3 0.0 2.5 2 1 1 3 3 3 1 Cutinase NUDIX PF00293.23 KNZ78462.1 - 1e-18 67.3 0.0 7.2e-18 64.5 0.0 2.2 1 1 0 1 1 1 1 NUDIX domain ubiquitin PF00240.18 KNZ78463.1 - 5.8e-08 32.0 0.0 1.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family NIF PF03031.13 KNZ78463.1 - 0.00034 20.3 0.0 0.00066 19.3 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PCI_Csn8 PF10075.4 KNZ78464.1 - 5.9e-15 55.2 0.0 1.9e-14 53.6 0.0 1.8 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF1681 PF07933.9 KNZ78465.1 - 1.7e-47 160.9 0.0 2e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Rab_eff_C PF04698.7 KNZ78465.1 - 0.16 10.0 0.0 0.18 9.8 0.0 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus Glyco_hydro_6 PF01341.12 KNZ78466.1 - 1.3e-111 372.8 2.4 1.6e-111 372.5 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 KNZ78466.1 - 1.1e-12 47.3 5.4 2.7e-12 46.1 3.7 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Aminotran_5 PF00266.14 KNZ78467.1 - 5e-95 318.3 0.0 6e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KNZ78467.1 - 0.009 14.3 0.0 0.014 13.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RRM_1 PF00076.17 KNZ78468.1 - 1.2e-29 101.6 0.0 3.6e-17 61.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ78468.1 - 4.8e-23 80.9 0.0 6.1e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ78468.1 - 4.7e-18 64.7 0.0 5.1e-11 42.2 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KNZ78468.1 - 0.00042 20.1 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 KNZ78468.1 - 0.0009 18.9 0.1 1.4 8.7 0.0 2.5 2 0 0 2 2 2 2 Limkain b1 Nup35_RRM_2 PF14605.1 KNZ78468.1 - 0.0009 18.9 0.0 0.019 14.7 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 KNZ78468.1 - 0.0029 17.2 0.8 0.37 10.3 0.0 2.9 3 0 0 3 3 3 1 Calcipressin CAP_GLY PF01302.20 KNZ78469.1 - 1.7e-20 72.4 0.3 4e-20 71.2 0.1 1.7 2 0 0 2 2 2 1 CAP-Gly domain LRR_4 PF12799.2 KNZ78469.1 - 1.4e-12 46.8 5.7 8.2e-06 25.3 0.0 5.2 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNZ78469.1 - 3e-08 33.2 5.7 0.00094 18.8 0.1 4.5 3 2 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 KNZ78469.1 - 5.7e-05 22.7 0.0 0.0025 17.3 0.0 2.4 1 1 2 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.28 KNZ78469.1 - 0.00039 20.0 11.2 2.4 8.5 0.0 6.6 6 2 1 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 KNZ78469.1 - 0.0017 18.2 6.3 3.8 8.1 0.0 6.0 6 0 0 6 6 6 1 Leucine rich repeat LRR_6 PF13516.1 KNZ78469.1 - 0.02 14.9 12.6 9 6.7 0.0 7.0 8 0 0 8 8 8 0 Leucine Rich repeat Phenol_monoox PF04663.7 KNZ78469.1 - 0.12 12.1 0.5 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 Phenol hydroxylase conserved region ECH_C PF13766.1 KNZ78470.1 - 3.9e-30 104.4 0.2 8.6e-30 103.3 0.0 1.7 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KNZ78470.1 - 1.7e-25 89.6 0.0 1.2e-24 86.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family IDO PF01231.13 KNZ78471.1 - 3.6e-98 328.7 0.0 4.2e-98 328.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Rep_fac-A_C PF08646.5 KNZ78472.1 - 7.4e-49 165.1 1.3 8.5e-47 158.5 0.4 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KNZ78472.1 - 1.7e-18 66.2 0.1 5.1e-18 64.7 0.0 1.9 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KNZ78472.1 - 9.8e-15 54.1 0.1 2.5e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain PG_binding_3 PF09374.5 KNZ78472.1 - 0.037 14.0 0.0 0.09 12.7 0.0 1.7 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Tmpp129 PF10272.4 KNZ78473.1 - 0.073 11.7 0.5 0.11 11.2 0.4 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor ABC_tran PF00005.22 KNZ78474.1 - 1.1e-60 203.8 0.0 1.4e-33 116.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KNZ78474.1 - 3.4e-57 193.9 25.0 2.3e-36 125.6 5.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KNZ78474.1 - 2.4e-15 56.3 0.4 8.8e-05 21.8 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KNZ78474.1 - 1.4e-10 42.0 0.0 0.00033 21.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KNZ78474.1 - 1e-09 38.8 0.0 0.32 10.9 0.0 4.4 3 1 0 4 4 4 2 AAA domain AAA_16 PF13191.1 KNZ78474.1 - 5e-09 36.4 0.8 0.0022 18.0 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KNZ78474.1 - 5e-09 35.5 0.5 0.0045 16.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 KNZ78474.1 - 9.2e-08 31.8 1.4 0.11 11.8 0.0 3.4 3 0 0 3 3 3 3 AAA-like domain AAA_18 PF13238.1 KNZ78474.1 - 1.2e-07 32.1 0.0 0.016 15.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KNZ78474.1 - 8.4e-07 29.1 0.7 0.084 13.0 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KNZ78474.1 - 1.8e-06 27.4 0.1 0.12 11.7 0.0 3.6 4 0 0 4 4 4 2 AAA domain DUF87 PF01935.12 KNZ78474.1 - 2.9e-06 27.2 0.2 0.027 14.3 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 IstB_IS21 PF01695.12 KNZ78474.1 - 9.6e-06 25.1 0.1 5.8 6.2 0.0 4.4 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF258 PF03193.11 KNZ78474.1 - 2.2e-05 23.7 0.0 0.098 11.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_5 PF07728.9 KNZ78474.1 - 2.3e-05 24.1 0.1 0.95 9.1 0.0 3.9 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 KNZ78474.1 - 5.9e-05 22.6 0.0 0.24 10.8 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_33 PF13671.1 KNZ78474.1 - 0.00014 21.7 0.0 0.57 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KNZ78474.1 - 0.00019 21.0 0.0 0.07 12.6 0.0 3.1 3 1 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 KNZ78474.1 - 0.00025 20.9 0.0 0.52 10.2 0.0 2.8 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 KNZ78474.1 - 0.00034 20.6 0.2 1.1 9.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KNZ78474.1 - 0.00041 19.8 0.0 1.6 8.1 0.0 3.5 4 0 0 4 4 4 1 Sigma-54 interaction domain CbiA PF01656.18 KNZ78474.1 - 0.00096 18.6 0.1 0.34 10.2 0.0 2.5 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.15 KNZ78474.1 - 0.0013 18.4 0.1 1.9 8.1 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase MobB PF03205.9 KNZ78474.1 - 0.0013 18.4 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DEAD PF00270.24 KNZ78474.1 - 0.002 17.6 0.0 0.05 13.1 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase G-alpha PF00503.15 KNZ78474.1 - 0.003 16.3 0.0 1.1 7.9 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit Mg_chelatase PF01078.16 KNZ78474.1 - 0.0039 16.3 0.0 0.74 8.9 0.0 3.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_ATPase PF09818.4 KNZ78474.1 - 0.0058 15.2 0.0 0.038 12.5 0.0 2.3 3 0 0 3 3 3 1 Predicted ATPase of the ABC class Sigma54_activ_2 PF14532.1 KNZ78474.1 - 0.0064 16.5 0.0 6.9 6.7 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 KNZ78474.1 - 0.0067 15.5 0.2 4.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 KNZ78474.1 - 0.0092 16.3 0.0 1.7 8.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KNZ78474.1 - 0.02 14.7 0.0 5.2 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 KNZ78474.1 - 0.025 14.2 0.0 8.5 6.0 0.0 2.7 2 0 0 2 2 2 0 NACHT domain PRK PF00485.13 KNZ78474.1 - 0.035 13.6 0.0 5.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.17 KNZ78474.1 - 0.041 13.3 0.0 10 5.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 KNZ78474.1 - 0.044 13.3 0.2 38 3.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 KNZ78474.1 - 0.048 13.6 0.1 6.9 6.6 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3987 PF13148.1 KNZ78474.1 - 0.048 12.2 0.2 2.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) CPT PF07931.7 KNZ78474.1 - 0.051 13.2 0.2 9.6 5.7 0.1 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Thymidylate_kin PF02223.12 KNZ78474.1 - 0.053 12.8 0.0 5.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase RNA_helicase PF00910.17 KNZ78474.1 - 0.061 13.5 0.0 18 5.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 KNZ78474.1 - 0.074 11.8 0.0 7 5.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 KNZ78474.1 - 0.12 11.5 0.2 15 4.5 0.0 2.7 3 0 0 3 3 3 0 KaiC Guanylate_kin PF00625.16 KNZ78474.1 - 0.19 11.1 0.0 7.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase ResIII PF04851.10 KNZ78474.1 - 0.32 10.7 0.0 19 5.0 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_13 PF13166.1 KNZ78474.1 - 0.58 8.5 0.0 17 3.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain DUF1776 PF08643.5 KNZ78475.1 - 1.3e-17 63.9 0.0 2.1e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) CPDase PF07823.6 KNZ78476.1 - 3.7e-23 82.0 0.0 5e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 KNZ78476.1 - 5.4e-08 32.6 0.0 6.1e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 KNZ78476.1 - 7.1e-05 22.7 0.0 0.46 10.4 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase tRNA-synt_1c PF00749.16 KNZ78477.1 - 3.5e-105 351.1 0.1 4.7e-105 350.7 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KNZ78477.1 - 1.8e-36 125.3 0.3 3e-36 124.6 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KNZ78477.1 - 1.5e-05 25.3 0.4 5.6e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KNZ78477.1 - 3.1e-05 23.7 0.0 7.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KNZ78477.1 - 0.02 14.8 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA_m1G_MT PF01746.16 KNZ78477.1 - 0.045 13.3 0.0 1.7 8.1 0.0 2.3 1 1 1 2 2 2 0 tRNA (Guanine-1)-methyltransferase APG9 PF04109.11 KNZ78478.1 - 1.3e-154 514.6 0.7 1.7e-154 514.1 0.5 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 HMGL-like PF00682.14 KNZ78478.1 - 5.9e-49 166.8 0.0 1e-48 166.0 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KNZ78478.1 - 1e-44 151.5 3.0 5.5e-23 81.2 0.0 2.4 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain DUF77 PF01910.12 KNZ78479.1 - 3.8e-21 74.5 0.0 1.1e-20 73.0 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function DUF77 DNA_methylase PF00145.12 KNZ78480.1 - 1.1e-46 159.4 0.0 2.1e-45 155.3 0.0 2.8 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 KNZ78480.1 - 2.4e-28 98.2 0.0 1.7e-18 66.4 0.0 2.5 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.3 KNZ78480.1 - 5.5e-08 32.6 0.1 2.4e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain MCM PF00493.18 KNZ78481.1 - 5.8e-134 446.0 0.2 2.3e-133 444.0 0.0 1.9 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 KNZ78481.1 - 4e-28 98.3 0.6 1.1e-27 96.8 0.2 2.0 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 KNZ78481.1 - 2.7e-08 33.6 0.0 7.3e-06 25.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KNZ78481.1 - 1.3e-07 31.0 0.1 1.6e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Mg_chelatase_2 PF13335.1 KNZ78481.1 - 2.8e-05 24.4 1.4 7.7e-05 23.0 0.4 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KNZ78481.1 - 0.05 13.2 0.0 0.18 11.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KNZ78481.1 - 0.054 12.9 0.0 0.72 9.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Peptidase_S8 PF00082.17 KNZ78482.1 - 1.2e-52 178.8 1.1 1.7e-52 178.3 0.7 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KNZ78482.1 - 3.3e-28 97.3 0.4 5.9e-28 96.4 0.3 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF2914 PF11141.3 KNZ78482.1 - 0.029 13.9 0.3 0.062 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) VPEP PF07589.6 KNZ78482.1 - 0.092 12.6 2.4 0.34 10.8 1.7 2.1 1 0 0 1 1 1 0 PEP-CTERM motif Peptidase_S8 PF00082.17 KNZ78483.1 - 1.5e-52 178.4 3.7 2.5e-52 177.7 2.5 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KNZ78483.1 - 1.4e-28 98.4 0.1 3.5e-28 97.2 0.1 1.7 2 0 0 2 2 2 1 Proprotein convertase P-domain POT1 PF02765.12 KNZ78484.1 - 5.5e-09 36.0 0.0 1.9e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Phosducin PF02114.11 KNZ78485.1 - 2.5e-17 62.4 0.8 4.3e-07 28.9 0.0 3.1 2 1 1 3 3 3 3 Phosducin DUF2839 PF10999.3 KNZ78485.1 - 0.12 12.3 0.8 0.29 11.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) GMC_oxred_N PF00732.14 KNZ78487.1 - 8.7e-33 113.7 0.0 9.4e-26 90.6 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ78487.1 - 1e-24 87.4 0.0 1.7e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 KNZ78487.1 - 3e-05 24.1 0.0 0.022 14.8 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KNZ78487.1 - 0.0007 19.5 0.0 0.0019 18.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ78487.1 - 0.0008 19.3 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KNZ78487.1 - 0.0023 16.9 0.1 0.0035 16.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KNZ78487.1 - 0.013 14.3 0.2 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 KNZ78487.1 - 0.028 13.3 0.2 0.062 12.1 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KNZ78487.1 - 0.083 11.3 0.1 0.14 10.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.16 KNZ78487.1 - 0.099 12.4 0.2 0.47 10.2 0.1 2.1 2 0 0 2 2 2 0 ThiF family 3HCDH_N PF02737.13 KNZ78487.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KNZ78487.1 - 0.14 11.5 0.7 4.1 6.7 0.1 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 KNZ78487.1 - 0.15 11.0 0.1 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KNZ78487.1 - 0.19 10.5 0.1 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A SMC_N PF02463.14 KNZ78488.1 - 1.6e-60 204.0 0.0 1e-56 191.6 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KNZ78488.1 - 2.3e-30 105.0 0.0 1.5e-29 102.3 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KNZ78488.1 - 4.5e-14 53.0 7.1 9.7e-07 29.0 0.2 3.0 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KNZ78488.1 - 2.3e-12 47.6 20.5 2.3e-12 47.6 14.2 6.1 2 2 2 4 4 1 1 AAA domain ABC_tran PF00005.22 KNZ78488.1 - 0.00059 20.1 13.8 0.097 12.9 1.5 4.7 2 2 0 3 3 3 2 ABC transporter AAA_29 PF13555.1 KNZ78488.1 - 0.00064 19.2 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Baculo_PEP_C PF04513.7 KNZ78488.1 - 0.011 15.6 3.2 0.011 15.6 2.2 6.4 4 2 1 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 KNZ78488.1 - 0.036 13.2 19.9 0.36 9.9 0.6 5.5 2 2 1 5 5 5 0 Reovirus sigma C capsid protein UPF0184 PF03670.8 KNZ78488.1 - 0.31 11.2 11.8 2.2 8.4 0.4 4.8 2 2 2 4 4 4 0 Uncharacterised protein family (UPF0184) Strep_SA_rep PF06696.6 KNZ78488.1 - 0.49 10.2 6.8 9.4 6.1 0.4 3.2 2 0 0 2 2 2 0 Streptococcal surface antigen repeat AAA_13 PF13166.1 KNZ78488.1 - 6.7 5.0 72.2 0.078 11.4 1.8 5.9 3 2 1 6 6 6 0 AAA domain NuA4 PF09340.5 KNZ78488.1 - 9.1 6.0 11.9 14 5.3 0.0 4.8 4 0 0 4 4 4 0 Histone acetyltransferase subunit NuA4 Coq4 PF05019.8 KNZ78489.1 - 4.5e-95 316.7 0.0 5.4e-95 316.5 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Pkinase PF00069.20 KNZ78490.1 - 0.0078 15.3 0.0 0.022 13.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain DNA_pol_A_exo1 PF01612.15 KNZ78491.1 - 4.3e-47 159.8 0.4 8e-47 158.9 0.3 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 KNZ78491.1 - 1.1e-13 50.6 0.1 2.8e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.7 KNZ78491.1 - 3.7e-09 36.7 0.5 1e-07 32.1 0.1 3.1 3 0 0 3 3 3 1 PMC2NT (NUC016) domain MFS_1 PF07690.11 KNZ78492.1 - 1.2e-08 34.1 7.0 5.8e-08 31.8 4.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Gram_pos_anchor PF00746.16 KNZ78492.1 - 0.35 10.7 3.8 12 5.8 0.0 2.7 3 0 0 3 3 3 0 Gram positive anchor MFS_1 PF07690.11 KNZ78494.1 - 2.3e-45 154.8 47.5 4.1e-44 150.7 20.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily LAB_N PF07578.6 KNZ78494.1 - 0.01 15.7 2.3 0.17 11.7 0.3 2.9 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain CRAL_TRIO PF00650.15 KNZ78495.1 - 4.6e-23 81.4 0.0 6.8e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KNZ78495.1 - 2.1e-07 30.9 0.6 3.8e-07 30.1 0.1 1.7 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain TPR_11 PF13414.1 KNZ78496.1 - 2.3e-18 65.6 0.6 1.1e-13 50.6 0.4 2.3 1 1 1 2 2 2 2 TPR repeat RPAP3_C PF13877.1 KNZ78496.1 - 4.6e-15 55.3 0.0 7.6e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.23 KNZ78496.1 - 1.1e-14 53.3 1.1 4.6e-05 22.8 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ78496.1 - 1.7e-11 43.1 1.3 0.00028 20.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ78496.1 - 3.9e-07 30.5 0.8 4.9e-06 27.0 0.3 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ78496.1 - 0.00033 20.9 0.4 0.014 15.7 0.1 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ78496.1 - 0.00066 20.1 0.5 0.14 12.8 0.0 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ78496.1 - 0.0038 17.3 0.3 0.94 9.8 0.2 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ78496.1 - 0.02 14.8 0.6 0.076 12.9 0.2 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ78496.1 - 0.034 14.5 0.1 0.77 10.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ78496.1 - 0.047 13.4 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 KNZ78496.1 - 0.047 12.7 0.0 3.2 6.7 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ78496.1 - 0.071 12.9 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ78496.1 - 0.072 12.9 0.5 34 4.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Herpes_Helicase PF02689.9 KNZ78497.1 - 0.0018 16.1 0.1 0.0019 16.0 0.0 1.0 1 0 0 1 1 1 1 Helicase Ribosomal_S17 PF00366.15 KNZ78498.1 - 1.6e-11 44.0 0.5 2e-11 43.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 PP2C PF00481.16 KNZ78499.1 - 6.1e-35 120.8 0.0 1e-34 120.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Prefoldin_2 PF01920.15 KNZ78499.1 - 2.2e-21 75.5 9.2 2.2e-21 75.5 6.4 1.7 1 1 0 1 1 1 1 Prefoldin subunit PP2C_2 PF13672.1 KNZ78499.1 - 0.0013 18.2 0.0 0.0046 16.3 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C IncA PF04156.9 KNZ78499.1 - 0.0023 17.5 9.4 0.0039 16.8 6.5 1.3 1 0 0 1 1 1 1 IncA protein PapG_C PF03628.8 KNZ78499.1 - 0.14 11.8 0.0 6.8 6.4 0.0 2.3 2 0 0 2 2 2 0 PapG chaperone-binding domain Snapin_Pallidin PF14712.1 KNZ78499.1 - 2.9 8.2 10.8 0.32 11.3 1.6 2.5 2 1 0 2 2 2 0 Snapin/Pallidin DUF641 PF04859.7 KNZ78499.1 - 3.3 7.4 11.7 2.1 8.1 1.7 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Snf7 PF03357.16 KNZ78500.1 - 1.5e-28 99.2 7.5 1.7e-28 99.1 5.2 1.0 1 0 0 1 1 1 1 Snf7 Tsp45I PF06300.7 KNZ78500.1 - 0.059 12.8 0.1 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Tsp45I type II restriction enzyme DUF458 PF04308.7 KNZ78500.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF458) Pro_isomerase PF00160.16 KNZ78501.1 - 2.1e-41 141.6 0.0 3.4e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 KNZ78501.1 - 0.031 14.2 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 U-box domain DUF104 PF01954.11 KNZ78501.1 - 0.16 12.0 0.2 0.3 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF104 PPR_2 PF13041.1 KNZ78502.1 - 2.1e-41 139.6 0.0 2.1e-06 27.6 0.0 10.1 6 3 4 10 10 10 9 PPR repeat family PPR_3 PF13812.1 KNZ78502.1 - 2.5e-33 111.5 7.0 0.00089 19.3 0.0 10.4 11 0 0 11 11 11 7 Pentatricopeptide repeat domain PPR_1 PF12854.2 KNZ78502.1 - 3.3e-18 64.8 0.1 0.06 12.8 0.0 8.5 8 0 0 8 8 8 5 PPR repeat PPR PF01535.15 KNZ78502.1 - 5e-18 63.7 7.2 0.031 14.2 0.0 10.2 11 0 0 11 11 11 4 PPR repeat ECSIT PF06239.6 KNZ78502.1 - 0.15 10.8 0.0 11 4.7 0.0 3.3 3 1 1 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway Kin17_mid PF10357.4 KNZ78503.1 - 3.4e-43 146.3 1.3 5.4e-37 126.2 0.2 2.4 1 1 1 2 2 2 2 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 KNZ78503.1 - 5.6e-05 23.1 4.1 0.00012 22.0 2.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KNZ78503.1 - 0.00015 21.7 4.8 0.00042 20.4 3.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KNZ78503.1 - 0.00043 20.3 2.9 0.00048 20.1 0.4 2.0 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Sugar_tr PF00083.19 KNZ78504.1 - 8.9e-100 334.3 15.0 2.1e-99 333.1 10.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ78504.1 - 2.1e-28 99.0 27.4 1.8e-19 69.6 3.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.24 KNZ78505.1 - 4.3e-20 71.8 0.0 4.4e-19 68.5 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ78505.1 - 2.5e-09 36.8 0.0 4.2e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KNZ78505.1 - 0.039 13.0 0.0 0.17 10.9 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF4203 PF13886.1 KNZ78506.1 - 3.3e-34 118.1 28.5 6.7e-32 110.6 19.8 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) LAG1-DNAbind PF09271.6 KNZ78506.1 - 8e-25 87.9 0.0 2e-23 83.4 0.0 2.5 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 KNZ78506.1 - 8.8e-25 87.2 0.0 1.9e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain PK PF00224.16 KNZ78507.1 - 4e-155 515.6 0.1 5e-155 515.3 0.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KNZ78507.1 - 1.4e-30 105.2 0.0 3e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KNZ78507.1 - 5.2e-05 22.2 0.4 0.00012 21.0 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 KNZ78507.1 - 0.0036 16.2 0.1 0.057 12.3 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Gly_transf_sug PF04488.10 KNZ78508.1 - 0.00013 22.3 0.0 0.00025 21.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KNZ78508.1 - 0.078 12.1 0.2 0.12 11.4 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Ribul_P_3_epim PF00834.14 KNZ78509.1 - 2.6e-63 212.7 0.0 3.2e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.5 KNZ78509.1 - 0.034 14.1 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 Predicted Peptidoglycan domain PcrB PF01884.12 KNZ78509.1 - 0.038 13.2 0.2 0.076 12.2 0.1 1.6 1 1 1 2 2 2 0 PcrB family OMPdecase PF00215.19 KNZ78509.1 - 0.065 12.6 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Myosin_N PF02736.14 KNZ78510.1 - 0.067 12.8 3.0 4.1 7.1 0.6 2.3 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Cyclin_N PF00134.18 KNZ78511.1 - 1.3e-11 44.1 0.5 3.5e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 KNZ78511.1 - 0.00036 20.2 0.0 0.032 14.0 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 KNZ78511.1 - 0.04 13.8 0.3 0.29 11.0 0.0 2.4 2 1 1 3 3 3 0 Cyclin, C-terminal domain Telomere_Sde2 PF13019.1 KNZ78511.1 - 5.2 6.7 7.1 3.1 7.4 3.4 1.8 2 0 0 2 2 2 0 Telomere stability and silencing RINGv PF12906.2 KNZ78512.1 - 2.3e-12 46.7 4.9 3.6e-12 46.1 3.4 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KNZ78512.1 - 0.0014 18.4 5.7 0.0021 17.8 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain DUF3974 PF13120.1 KNZ78512.1 - 0.088 12.6 0.2 0.2 11.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) zf-RING_4 PF14570.1 KNZ78512.1 - 0.11 12.0 2.4 0.22 11.1 1.6 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KNZ78512.1 - 1 9.0 4.2 1.7 8.4 2.9 1.4 1 0 0 1 1 1 0 PHD-finger Mito_carr PF00153.22 KNZ78513.1 - 4.9e-40 135.1 0.1 2.5e-15 55.9 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein RNase_T PF00929.19 KNZ78514.1 - 1.6e-10 41.4 0.0 1.9e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF3025 PF11227.3 KNZ78514.1 - 0.068 12.6 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) GSH-S_N PF02951.9 KNZ78515.1 - 0.073 12.8 0.7 0.15 11.8 0.1 1.8 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, N-terminal domain Mito_fiss_reg PF05308.6 KNZ78516.1 - 0.16 11.3 5.6 0.39 10.0 3.9 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator Cas1_AcylT PF07779.7 KNZ78517.1 - 1.8e-163 544.5 21.1 2.8e-163 543.9 14.6 1.2 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 KNZ78517.1 - 5.2e-26 92.0 0.0 8.6e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Rhomboid PF01694.17 KNZ78518.1 - 1.8e-31 109.1 15.1 1.8e-31 109.1 10.4 1.9 1 1 1 2 2 2 1 Rhomboid family DUF1426 PF07234.6 KNZ78518.1 - 5.7 6.6 5.6 22 4.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1426) DIL PF01843.14 KNZ78519.1 - 6.9e-21 74.1 0.2 1.4e-20 73.0 0.2 1.6 1 0 0 1 1 1 1 DIL domain Ank PF00023.25 KNZ78519.1 - 6.2e-09 35.2 0.2 0.00011 21.7 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KNZ78519.1 - 9e-08 32.3 0.0 2.7e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNZ78519.1 - 2.6e-06 27.7 0.1 0.0023 18.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ78519.1 - 0.00042 20.2 0.3 0.0046 17.0 0.0 3.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 KNZ78519.1 - 0.00045 20.3 0.1 0.003 17.7 0.1 2.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Rrp15p PF07890.7 KNZ78520.1 - 1.9e-19 70.0 5.8 1.9e-19 70.0 4.0 2.7 1 1 1 2 2 2 1 Rrp15p RE_XcyI PF09571.5 KNZ78520.1 - 0.0039 16.0 0.3 0.0047 15.8 0.2 1.1 1 0 0 1 1 1 1 XcyI restriction endonuclease DUF3801 PF12687.2 KNZ78520.1 - 4.4 6.8 11.8 0.59 9.6 4.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Hid1 PF12722.2 KNZ78520.1 - 9.3 3.7 8.0 11 3.5 5.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pkinase PF00069.20 KNZ78521.1 - 3.4e-65 219.7 0.0 4.8e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ78521.1 - 3.6e-45 154.0 0.0 5.7e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ78521.1 - 4.5e-10 38.9 0.0 1.5e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Ras_bdg_2 PF14847.1 KNZ78521.1 - 0.015 15.2 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Kdo PF06293.9 KNZ78521.1 - 0.016 14.2 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF866 PF05907.8 KNZ78522.1 - 6.5e-30 103.7 0.0 6.9e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) MRP-S28 PF10213.4 KNZ78523.1 - 5.8e-28 97.5 0.0 9.1e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Septin PF00735.13 KNZ78524.1 - 3.4e-118 393.7 0.1 3.4e-118 393.7 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KNZ78524.1 - 1.5e-06 28.1 0.0 3.4e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KNZ78524.1 - 3e-05 23.5 0.3 0.017 14.5 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KNZ78524.1 - 6.6e-05 22.1 0.0 0.00027 20.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KNZ78524.1 - 9.7e-05 22.5 0.1 0.0012 19.0 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KNZ78524.1 - 0.0027 17.7 0.1 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 KNZ78524.1 - 0.0044 16.6 0.4 0.012 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KNZ78524.1 - 0.008 16.4 5.5 0.15 12.3 0.4 2.8 2 1 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 KNZ78524.1 - 0.026 14.2 1.9 0.52 9.9 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase Dynamin_N PF00350.18 KNZ78524.1 - 0.043 13.6 3.3 3.3 7.4 0.0 3.1 2 1 0 3 3 3 0 Dynamin family RNA_helicase PF00910.17 KNZ78524.1 - 0.054 13.6 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Phage_GPO PF05929.6 KNZ78524.1 - 0.057 12.6 3.5 0.1 11.8 2.4 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase AAA_29 PF13555.1 KNZ78524.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Strep_SA_rep PF06696.6 KNZ78524.1 - 0.15 11.8 5.0 0.08 12.7 0.7 2.4 1 1 1 2 2 2 0 Streptococcal surface antigen repeat Exonuc_VII_L PF02601.10 KNZ78524.1 - 0.29 10.2 4.9 0.59 9.2 3.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Xpo1 PF08389.7 KNZ78525.1 - 4.4e-20 72.1 0.4 2.1e-18 66.6 0.1 3.4 2 1 1 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KNZ78525.1 - 1.8e-07 30.9 0.0 1.4e-05 24.9 0.0 3.3 2 1 1 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.17 KNZ78525.1 - 0.014 15.4 0.0 4 7.7 0.0 3.5 2 0 0 2 2 2 0 HEAT repeat CoA_binding PF02629.14 KNZ78526.1 - 1.7e-29 102.1 1.6 5.7e-29 100.4 0.2 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KNZ78526.1 - 4.1e-23 81.6 0.0 6.6e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KNZ78526.1 - 1.6e-09 37.4 0.0 4e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KNZ78526.1 - 0.0022 18.1 0.6 0.0085 16.2 0.0 2.2 2 1 1 3 3 3 1 CoA binding domain GFO_IDH_MocA PF01408.17 KNZ78526.1 - 0.0029 18.1 0.0 0.0066 16.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ACBP PF00887.14 KNZ78527.1 - 1.9e-19 69.0 0.0 3.2e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_4 PF13637.1 KNZ78527.1 - 4.8e-16 58.7 0.0 4e-08 33.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KNZ78527.1 - 1.8e-12 47.0 0.0 4.6e-12 45.7 0.0 1.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KNZ78527.1 - 1.6e-11 44.3 0.0 2.6e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ78527.1 - 2.5e-10 39.6 0.0 1.2e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 KNZ78527.1 - 5.1e-08 32.4 0.0 8.2e-06 25.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ribosomal_S16 PF00886.14 KNZ78528.1 - 4e-15 55.2 0.0 1.1e-14 53.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S16 LSM PF01423.17 KNZ78529.1 - 1e-16 60.1 0.0 1.2e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain Arm PF00514.18 KNZ78530.1 - 1.9e-92 300.2 13.3 6.2e-13 48.0 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KNZ78530.1 - 3.6e-23 81.3 4.3 2.3e-09 37.4 0.0 5.3 4 1 1 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.1 KNZ78530.1 - 1.5e-22 79.6 0.7 1.1e-07 32.0 0.0 6.1 2 1 5 7 7 7 4 HEAT repeats IBB PF01749.15 KNZ78530.1 - 8.9e-19 67.4 3.1 1.5e-18 66.7 2.2 1.3 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 KNZ78530.1 - 3.5e-17 60.8 0.3 9.2e-05 22.2 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat Arm_2 PF04826.8 KNZ78530.1 - 1.9e-07 30.4 0.0 0.065 12.3 0.0 4.1 3 1 1 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 KNZ78530.1 - 4.3e-06 25.3 0.0 0.0009 17.6 0.0 2.8 1 1 2 3 3 3 1 Adaptin N terminal region RICTOR_V PF14668.1 KNZ78530.1 - 8e-06 25.6 2.2 0.034 14.0 0.0 4.4 3 2 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 KNZ78530.1 - 0.00034 20.8 2.4 0.41 11.2 0.1 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 KNZ78530.1 - 0.0011 18.8 0.0 0.71 9.8 0.0 4.3 3 2 1 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 KNZ78530.1 - 0.022 13.0 0.0 2 6.5 0.0 2.8 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit Mo25 PF08569.6 KNZ78530.1 - 0.041 12.9 0.0 0.099 11.6 0.0 1.6 1 0 0 1 1 1 0 Mo25-like Kri1 PF05178.7 KNZ78530.1 - 0.07 13.4 1.0 0.12 12.6 0.7 1.4 1 0 0 1 1 1 0 KRI1-like family V-ATPase_H_N PF03224.9 KNZ78530.1 - 0.093 11.8 0.0 13 4.7 0.0 2.9 1 1 1 2 2 2 0 V-ATPase subunit H Glycos_trans_3N PF02885.12 KNZ78530.1 - 0.11 12.0 0.0 5.3 6.7 0.0 3.1 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain DUF3552 PF12072.3 KNZ78530.1 - 0.48 9.6 5.9 0.83 8.8 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) 2-Hacid_dh_C PF02826.14 KNZ78531.1 - 2.6e-58 196.1 0.1 3.8e-58 195.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KNZ78531.1 - 2e-11 43.5 0.0 2.5e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KNZ78531.1 - 3.9e-05 23.5 0.0 8.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PC_rep PF01851.17 KNZ78532.1 - 2.8e-31 105.9 24.7 7.8e-08 32.1 0.0 9.4 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KNZ78532.1 - 1.6e-21 76.4 0.3 1.2e-09 38.3 0.0 4.3 2 1 4 6 6 6 4 HEAT repeats HEAT PF02985.17 KNZ78532.1 - 9.8e-07 28.3 0.2 0.71 10.1 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 KNZ78532.1 - 2.8e-06 27.6 0.8 0.14 12.7 0.0 4.4 3 0 0 3 3 3 2 HEAT-like repeat Adaptin_N PF01602.15 KNZ78532.1 - 0.16 10.2 0.0 2.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Adaptin N terminal region Nucleoporin_C PF03177.9 KNZ78533.1 - 2.5e-73 247.5 2.1 3.2e-73 247.2 1.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KNZ78533.1 - 7.1e-43 146.9 0.0 1.1e-42 146.3 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like NAD_binding_6 PF08030.7 KNZ78534.1 - 2.9e-23 82.5 0.0 6e-23 81.4 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KNZ78534.1 - 8.6e-22 77.0 0.0 2.5e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KNZ78534.1 - 1.6e-15 57.2 12.0 1.6e-15 57.2 8.3 2.1 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KNZ78534.1 - 0.00032 20.7 0.0 0.0011 19.1 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KNZ78534.1 - 0.003 18.0 0.0 0.19 12.3 0.0 2.3 1 1 0 2 2 2 1 Oxidoreductase NAD-binding domain HORMA PF02301.13 KNZ78535.1 - 1.6e-38 132.2 0.6 1.8e-38 132.0 0.4 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 KNZ78535.1 - 0.00021 20.8 0.9 0.00092 18.7 0.6 1.8 1 1 0 1 1 1 1 Autophagy-related protein 13 BaxI_1 PF12811.2 KNZ78535.1 - 0.034 13.2 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Bax inhibitor 1 like WD40 PF00400.27 KNZ78536.1 - 3.7e-60 197.7 16.2 1.2e-11 44.0 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KNZ78536.1 - 3.6e-29 101.6 0.0 8.7e-29 100.4 0.0 1.6 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 KNZ78536.1 - 0.025 14.3 0.0 9.8 5.8 0.0 2.4 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KNZ78536.1 - 0.038 12.1 1.7 9.1 4.2 0.0 3.2 1 1 1 3 3 3 0 Nucleoporin Nup120/160 LisH PF08513.6 KNZ78536.1 - 0.11 12.2 0.0 0.63 9.8 0.0 2.2 2 0 0 2 2 2 0 LisH OKR_DC_1 PF01276.15 KNZ78537.1 - 0.026 13.1 0.0 0.032 12.7 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Syndecan PF01034.15 KNZ78538.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain MGC-24 PF05283.6 KNZ78538.1 - 3.2 7.4 13.5 0.13 12.0 4.9 1.9 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Rifin_STEVOR PF02009.11 KNZ78539.1 - 0.00021 21.0 0.0 0.00033 20.3 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family EphA2_TM PF14575.1 KNZ78539.1 - 0.0038 17.5 0.0 0.0069 16.7 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 KNZ78539.1 - 0.0039 16.4 3.0 0.0091 15.2 2.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 KNZ78539.1 - 0.0068 16.1 0.4 0.0068 16.1 0.3 1.9 1 1 0 2 2 2 1 TMEM154 protein family DUF4448 PF14610.1 KNZ78539.1 - 0.0078 15.7 0.1 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Herpes_gE PF02480.11 KNZ78539.1 - 0.0088 14.3 0.1 0.014 13.7 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Mid2 PF04478.7 KNZ78539.1 - 0.01 15.2 0.2 0.019 14.3 0.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TrbC PF04956.8 KNZ78539.1 - 0.043 13.8 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 TrbC/VIRB2 family Glycophorin_A PF01102.13 KNZ78539.1 - 0.048 13.4 0.1 0.048 13.4 0.1 2.0 2 0 0 2 2 2 0 Glycophorin A Shisa PF13908.1 KNZ78539.1 - 0.05 13.7 0.4 0.09 12.9 0.3 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Protocadherin PF08374.6 KNZ78539.1 - 0.053 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Protocadherin Chisel PF15355.1 KNZ78539.1 - 0.07 13.1 0.2 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel MLANA PF14991.1 KNZ78539.1 - 0.11 12.5 0.3 0.27 11.2 0.2 1.6 1 1 0 1 1 1 0 Protein melan-A SCF PF02404.10 KNZ78539.1 - 0.19 10.8 0.1 0.34 10.0 0.1 1.3 1 0 0 1 1 1 0 Stem cell factor Podoplanin PF05808.6 KNZ78539.1 - 0.22 11.0 4.2 0.057 12.9 0.4 1.8 2 0 0 2 2 2 0 Podoplanin Meth_synt_2 PF01717.13 KNZ78540.1 - 1.5e-24 86.5 0.0 2.8e-24 85.7 0.0 1.4 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KNZ78540.1 - 4.3e-07 29.5 0.0 0.021 14.1 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Tom5 PF10642.4 KNZ78540.1 - 0.0053 16.3 1.5 0.01 15.4 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial import receptor subunit or translocase Ribosomal_L13e PF01294.13 KNZ78541.1 - 1e-65 220.5 7.2 1.6e-65 219.8 5.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e FA_desaturase PF00487.19 KNZ78542.1 - 7.3e-23 81.3 15.0 1e-22 80.8 10.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase His_biosynth PF00977.16 KNZ78543.1 - 5.8e-45 153.3 1.3 2.6e-44 151.2 0.9 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KNZ78543.1 - 2.3e-27 95.7 0.0 4e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 KNZ78543.1 - 3.7e-11 42.8 0.0 6.4e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 KNZ78543.1 - 0.00071 19.2 0.0 0.016 14.8 0.0 2.3 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 KNZ78543.1 - 0.08 12.3 0.3 0.49 9.7 0.2 2.0 1 1 0 1 1 1 0 Peptidase C26 2-Hacid_dh_C PF02826.14 KNZ78544.1 - 1.6e-52 177.2 0.0 6.6e-52 175.2 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KNZ78544.1 - 2.5e-33 114.3 0.0 3.1e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KNZ78544.1 - 0.041 13.7 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF2597 PF10772.4 KNZ78544.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) Rad51 PF08423.6 KNZ78545.1 - 1.5e-134 446.8 0.0 1.8e-134 446.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KNZ78545.1 - 9.5e-14 51.2 0.0 1.4e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 KNZ78545.1 - 1.6e-09 37.8 0.2 4.3e-09 36.4 0.2 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 KNZ78545.1 - 5.3e-07 29.0 0.0 7.1e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KNZ78545.1 - 3.4e-05 23.0 0.0 6e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 KaiC F-box-like PF12937.2 KNZ78546.1 - 1.3e-06 27.9 0.4 6.9e-06 25.7 0.1 2.5 3 0 0 3 3 3 1 F-box-like Ribosomal_L4 PF00573.17 KNZ78547.1 - 7.1e-60 201.6 0.0 8.7e-60 201.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.14 KNZ78548.1 - 4.3e-34 117.3 0.2 9.4e-34 116.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BRCT PF00533.21 KNZ78548.1 - 0.0061 16.6 0.0 0.43 10.7 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Tim17 PF02466.14 KNZ78549.1 - 6.8e-12 45.5 9.2 8.3e-12 45.2 6.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 KNZ78549.1 - 0.027 14.5 1.2 0.027 14.5 0.8 2.6 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide WD40 PF00400.27 KNZ78550.1 - 9.1e-16 57.0 1.9 2.7e-07 30.2 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat CCD PF07860.6 KNZ78551.1 - 0.13 11.6 1.3 47 3.4 0.0 3.4 1 1 3 5 5 5 0 WisP family C-Terminal Region NUC153 PF08159.7 KNZ78552.1 - 1e-11 44.2 11.1 2e-11 43.2 0.2 3.9 3 0 0 3 3 3 2 NUC153 domain CS PF04969.11 KNZ78553.1 - 0.025 15.0 0.1 0.045 14.3 0.1 1.4 1 0 0 1 1 1 0 CS domain PINIT PF14324.1 KNZ78554.1 - 1.1e-34 119.6 1.3 1.8e-34 118.9 0.9 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KNZ78554.1 - 7.6e-05 22.1 3.4 0.00018 20.9 2.4 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Mito_carr PF00153.22 KNZ78555.1 - 5.6e-65 215.0 4.4 2.7e-22 78.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_88 PF07470.8 KNZ78555.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 ResIII PF04851.10 KNZ78556.1 - 2.7e-19 69.6 0.0 4.8e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KNZ78556.1 - 7.2e-16 58.1 0.0 1.4e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ78556.1 - 1e-15 57.3 0.1 2.9e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KNZ78556.1 - 2.5e-07 29.8 0.0 4.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD_2 PF06733.10 KNZ78556.1 - 0.0026 17.2 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 AAA_22 PF13401.1 KNZ78556.1 - 0.016 15.3 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KNZ78556.1 - 0.025 13.5 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 KNZ78556.1 - 0.027 13.3 0.0 0.071 11.9 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein OapA PF04225.7 KNZ78556.1 - 0.13 12.2 0.0 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 Opacity-associated protein A LysM-like domain Helicase_C_2 PF13307.1 KNZ78556.1 - 0.13 12.1 0.1 0.59 10.0 0.0 2.1 3 0 0 3 3 3 0 Helicase C-terminal domain cobW PF02492.14 KNZ78556.1 - 0.14 11.6 0.0 0.34 10.3 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2680 PF10925.3 KNZ78556.1 - 0.28 11.0 1.2 0.59 10.0 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) Indigoidine_A PF04227.7 KNZ78557.1 - 4.3e-96 321.5 2.9 1.4e-70 237.8 0.7 2.2 1 1 1 2 2 2 2 Indigoidine synthase A like protein PfkB PF00294.19 KNZ78557.1 - 1.2e-11 44.3 0.0 2.6e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MoaE PF02391.12 KNZ78558.1 - 1.6e-31 108.5 0.0 2.3e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 MoaE protein ICE2 PF08426.5 KNZ78559.1 - 3.6e-24 85.1 30.5 2.6e-13 49.3 10.0 3.1 1 1 1 2 2 2 2 ICE2 SNAP PF14938.1 KNZ78560.1 - 5e-105 350.6 16.6 5.7e-105 350.5 11.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 KNZ78560.1 - 0.00057 19.4 9.1 0.15 11.9 0.1 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ78560.1 - 0.0014 18.2 13.2 0.012 15.2 0.6 3.9 3 1 1 4 4 4 2 TPR repeat Spatacsin_C PF14649.1 KNZ78560.1 - 0.0048 15.8 4.1 0.038 12.8 2.8 2.0 1 1 0 1 1 1 1 Spatacsin C-terminus TPR_12 PF13424.1 KNZ78560.1 - 0.0054 16.6 4.1 0.0054 16.6 2.9 3.1 2 1 0 3 3 3 1 Tetratricopeptide repeat TC1 PF15063.1 KNZ78560.1 - 0.17 11.4 1.4 0.43 10.1 0.2 2.2 2 0 0 2 2 2 0 Thyroid cancer protein 1 Erythro_esteras PF05139.9 KNZ78560.1 - 0.25 10.5 7.4 0.13 11.4 3.0 1.8 1 1 1 2 2 2 0 Erythromycin esterase NSF PF02071.15 KNZ78560.1 - 0.52 11.0 11.5 7.1 7.6 0.0 6.4 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_6 PF13174.1 KNZ78560.1 - 0.69 10.4 12.8 39 5.0 0.1 5.7 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ78560.1 - 1.8 9.3 14.5 0.22 12.2 0.5 4.0 2 2 1 3 3 3 0 Tetratricopeptide repeat Prenyltransf PF01255.14 KNZ78561.1 - 0.071 12.2 0.5 8.3 5.4 0.0 2.6 3 0 0 3 3 3 0 Putative undecaprenyl diphosphate synthase DUF2235 PF09994.4 KNZ78562.1 - 1.9e-51 175.0 0.0 2.3e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KNZ78562.1 - 0.0036 17.0 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_61 PF03443.9 KNZ78563.1 - 4.8e-56 189.9 0.0 7.3e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3923 PF13061.1 KNZ78563.1 - 0.081 12.7 0.5 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) TRAP_alpha PF03896.11 KNZ78564.1 - 0.071 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Glyco_hydro_2_N PF02837.13 KNZ78565.1 - 0.16 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Nup_retrotrp_bd PF10599.4 KNZ78565.1 - 4.3 8.0 7.8 6.7 7.4 5.5 1.4 1 1 0 1 1 1 0 Retro-transposon transporting motif Glyco_hydro_61 PF03443.9 KNZ78566.1 - 7.5e-37 127.2 0.1 9.4e-37 126.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ADH_N PF08240.7 KNZ78567.1 - 1e-17 63.8 0.6 1.8e-17 63.0 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KNZ78567.1 - 8.1e-13 48.0 0.1 1.6e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KNZ78567.1 - 0.00052 19.2 0.0 0.00098 18.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 KNZ78567.1 - 0.11 12.9 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Abhydrolase_6 PF12697.2 KNZ78568.1 - 3.9e-12 46.5 0.0 5.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ78568.1 - 5.9e-07 29.3 0.0 1.4e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KNZ78568.1 - 0.076 12.8 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_6 PF12697.2 KNZ78569.1 - 8.9e-16 58.4 0.0 1.3e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ78569.1 - 4.2e-06 26.5 0.0 6.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrophobin PF01185.13 KNZ78570.1 - 0.041 14.3 0.2 0.068 13.6 0.1 1.3 1 0 0 1 1 1 0 Fungal hydrophobin MCLC PF05934.6 KNZ78572.1 - 0.67 8.1 4.4 0.81 7.9 3.0 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) MARVEL PF01284.18 KNZ78572.1 - 1.1 9.0 17.8 6.3 6.6 8.6 2.4 2 1 0 2 2 2 0 Membrane-associating domain DUF4191 PF13829.1 KNZ78573.1 - 0.038 13.0 0.4 0.069 12.2 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) DUF202 PF02656.10 KNZ78573.1 - 6.8 6.9 9.4 4.4 7.5 1.2 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF202) p450 PF00067.17 KNZ78574.1 - 1.2e-57 195.5 0.1 2.2e-55 187.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 TPR_11 PF13414.1 KNZ78575.1 - 2.9e-23 81.2 21.4 0.0001 21.8 0.0 7.2 7 0 0 7 7 7 5 TPR repeat TPR_16 PF13432.1 KNZ78575.1 - 5.4e-17 61.9 24.7 2.9e-05 24.5 0.1 6.9 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ78575.1 - 3.1e-15 55.8 25.2 5.5e-07 29.4 0.2 7.9 6 2 4 10 10 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ78575.1 - 4.2e-15 54.3 22.9 0.0097 15.7 0.1 11.2 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ78575.1 - 3.1e-12 46.6 25.6 0.0058 16.9 0.2 8.2 6 2 2 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ78575.1 - 1.7e-11 43.6 24.8 0.032 14.8 0.1 11.3 8 2 4 12 12 11 3 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ78575.1 - 4.3e-10 38.7 14.1 0.065 12.8 0.0 8.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ78575.1 - 8.2e-09 34.6 9.5 0.23 11.3 0.0 9.3 11 0 0 11 11 10 1 Tetratricopeptide repeat Apc3 PF12895.2 KNZ78575.1 - 1.8e-08 34.3 17.1 0.11 12.6 0.7 7.2 6 2 2 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KNZ78575.1 - 1.5e-07 31.0 0.5 0.75 10.1 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ78575.1 - 7.2e-07 28.5 12.9 3.1 7.7 0.0 8.2 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ78575.1 - 3.2e-06 27.2 13.9 5.4 7.6 0.0 9.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_20 PF14561.1 KNZ78575.1 - 0.00047 20.2 8.3 0.14 12.2 0.2 5.6 5 1 0 5 5 4 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KNZ78575.1 - 0.0066 16.6 4.0 3.7 7.7 0.1 3.7 2 1 1 3 3 3 2 Alkyl sulfatase dimerisation TPR_9 PF13371.1 KNZ78575.1 - 0.01 15.6 12.6 0.35 10.7 0.1 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.5 KNZ78575.1 - 0.05 12.3 0.3 2.4 6.8 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Vps39_1 PF10366.4 KNZ78575.1 - 0.064 13.2 0.9 3.3 7.7 0.2 3.3 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 TPR_10 PF13374.1 KNZ78575.1 - 7.3 6.6 21.8 8.9 6.3 0.0 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat ABC_tran PF00005.22 KNZ78578.1 - 8.9e-51 171.7 0.0 1.8e-31 109.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KNZ78578.1 - 2.4e-30 105.9 29.5 6e-17 61.9 4.9 3.7 4 0 0 4 4 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 KNZ78578.1 - 3.6e-09 36.9 0.1 0.42 10.5 0.0 4.3 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 KNZ78578.1 - 1.2e-08 34.4 0.0 0.00032 19.9 0.1 4.1 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KNZ78578.1 - 4.2e-07 29.5 0.0 0.0057 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KNZ78578.1 - 4.7e-07 29.2 0.2 0.019 14.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KNZ78578.1 - 1.8e-06 28.4 0.1 0.00075 19.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KNZ78578.1 - 5.7e-06 26.4 0.6 0.1 12.5 0.2 2.8 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 KNZ78578.1 - 9e-06 24.7 0.6 0.049 12.5 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 KNZ78578.1 - 0.0011 19.0 1.5 9.2 6.4 0.5 3.4 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KNZ78578.1 - 0.0065 15.9 0.0 3.4 7.0 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family RseC_MucC PF04246.7 KNZ78578.1 - 0.01 15.3 3.2 0.014 15.0 0.0 2.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ABC_ATPase PF09818.4 KNZ78578.1 - 0.017 13.7 0.2 0.21 10.1 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_19 PF13245.1 KNZ78578.1 - 0.019 14.7 0.5 2 8.1 0.0 3.1 2 0 0 2 2 2 0 Part of AAA domain DUF87 PF01935.12 KNZ78578.1 - 0.019 14.8 0.2 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_17 PF13207.1 KNZ78578.1 - 0.031 15.0 0.1 10 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KNZ78578.1 - 0.033 14.1 0.1 1.9 8.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 KNZ78578.1 - 0.046 13.1 0.6 2.5 7.4 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 KNZ78578.1 - 0.07 12.8 0.2 0.82 9.3 0.0 2.5 3 0 0 3 3 2 0 Archaeal ATPase DUF258 PF03193.11 KNZ78578.1 - 0.097 11.8 0.0 7.1 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MobB PF03205.9 KNZ78578.1 - 0.12 12.1 0.2 5.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KNZ78578.1 - 0.12 12.8 0.0 21 5.6 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 KNZ78578.1 - 0.15 11.9 0.1 20 5.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KNZ78578.1 - 0.15 12.3 1.6 21 5.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KNZ78578.1 - 0.18 11.4 1.4 27 4.3 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 KNZ78578.1 - 0.27 10.0 0.4 1.3 7.8 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.7 KNZ78578.1 - 0.3 10.1 0.4 13 4.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 KNZ78578.1 - 0.87 9.2 3.6 5.4 6.6 0.0 3.2 4 0 0 4 4 4 0 NACHT domain FmdA_AmdA PF03069.10 KNZ78579.1 - 1.1e-73 248.0 0.0 1.4e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 Acetamidase/Formamidase family WD40 PF00400.27 KNZ78580.1 - 1.1e-181 583.1 69.5 1.5e-13 50.0 0.3 14.6 14 0 0 14 14 14 14 WD domain, G-beta repeat PD40 PF07676.7 KNZ78580.1 - 5.9e-12 44.9 3.1 6.4 6.5 0.0 10.7 11 0 0 11 11 11 1 WD40-like Beta Propeller Repeat NACHT PF05729.7 KNZ78580.1 - 3.2e-10 39.9 0.0 8.3e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KNZ78580.1 - 1.8e-06 28.1 0.0 5.8e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 KNZ78580.1 - 0.00064 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 KNZ78580.1 - 0.0012 19.0 0.0 0.0036 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ78580.1 - 0.0044 17.8 0.0 0.015 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KNZ78580.1 - 0.0047 16.4 0.0 0.042 13.3 0.0 2.7 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_19 PF13245.1 KNZ78580.1 - 0.0065 16.1 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 KNZ78580.1 - 0.015 15.4 0.0 0.069 13.3 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF814 PF05670.8 KNZ78580.1 - 0.024 14.4 0.0 0.091 12.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF814) AAA_18 PF13238.1 KNZ78580.1 - 0.027 14.7 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3339 PF11820.3 KNZ78580.1 - 0.06 13.6 0.2 45 4.4 0.0 4.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3339) UPF0079 PF02367.12 KNZ78580.1 - 0.071 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 KNZ78580.1 - 0.076 12.4 0.1 0.21 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KNZ78580.1 - 0.11 12.2 0.0 0.8 9.3 0.0 2.2 3 0 0 3 3 2 0 Archaeal ATPase AAA_14 PF13173.1 KNZ78580.1 - 0.15 11.9 0.0 0.41 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KNZ78580.1 - 0.24 10.9 0.0 0.51 9.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.6 KNZ78580.1 - 0.31 9.6 0.0 0.49 9.0 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Zeta_toxin PF06414.7 KNZ78580.1 - 0.46 9.5 0.0 0.83 8.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF2109 PF09882.4 KNZ78582.1 - 0.56 10.1 3.5 0.71 9.8 2.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2109) zf-RVT PF13966.1 KNZ78584.1 - 0.056 13.7 0.2 0.14 12.5 0.2 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Sulfatase_C PF14707.1 KNZ78586.1 - 0.11 12.7 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DAO PF01266.19 KNZ78587.1 - 6.5e-38 130.5 0.0 8e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KNZ78587.1 - 5.7e-05 23.2 0.0 0.037 14.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ78587.1 - 0.0021 18.0 0.1 0.0054 16.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KNZ78587.1 - 0.017 14.2 0.1 0.04 12.9 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KNZ78587.1 - 0.032 14.1 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNZ78587.1 - 0.06 13.1 0.1 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding zf-C2H2 PF00096.21 KNZ78588.1 - 0.45 10.9 4.8 1.1 9.7 3.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ78588.1 - 3.4 8.2 5.7 8.2 7.0 3.9 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Pyridox_oxidase PF01243.15 KNZ78591.1 - 0.00054 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase p450 PF00067.17 KNZ78594.1 - 7.9e-60 202.6 0.0 8.3e-50 169.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Retrotrans_gag PF03732.12 KNZ78596.1 - 0.078 13.0 0.1 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein BPL_LplA_LipB PF03099.14 KNZ78597.1 - 3.2e-14 53.0 0.0 5.4e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.4 KNZ78597.1 - 4.6e-05 23.0 0.0 0.00012 21.6 0.0 1.8 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus ORC6 PF05460.8 KNZ78600.1 - 0.096 11.7 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Terpene_synth_C PF03936.11 KNZ78601.1 - 8.4e-19 67.8 1.5 1.2e-18 67.3 1.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TB2_DP1_HVA22 PF03134.14 KNZ78602.1 - 8.2e-11 41.5 0.0 1.6e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family G10 PF01125.12 KNZ78603.1 - 1.3e-64 216.1 7.0 1.5e-64 215.9 4.8 1.0 1 0 0 1 1 1 1 G10 protein Na_H_Exchanger PF00999.16 KNZ78604.1 - 3.6e-48 164.0 43.0 5.5e-47 160.1 29.8 2.0 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Cys_Met_Meta_PP PF01053.15 KNZ78605.1 - 7e-132 439.3 0.0 8.1e-132 439.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KNZ78605.1 - 2e-09 36.9 0.0 3.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KNZ78605.1 - 7.3e-09 35.0 0.0 1.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KNZ78605.1 - 2.4e-06 26.9 0.0 3.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KNZ78605.1 - 3.9e-06 25.8 0.0 6.3e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 KNZ78605.1 - 0.0023 16.3 0.2 0.0049 15.2 0.1 1.5 2 0 0 2 2 2 1 Methionine gamma-lyase GDC-P PF02347.11 KNZ78605.1 - 0.025 13.2 0.0 0.036 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein DUF3384 PF11864.3 KNZ78606.1 - 0.0027 16.2 0.0 0.0035 15.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Acyltransferase PF01553.16 KNZ78607.1 - 1.5e-29 102.0 0.0 2.4e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase GDPD PF03009.12 KNZ78608.1 - 3.9e-26 92.0 0.0 4.5e-25 88.6 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family zf-CCHC PF00098.18 KNZ78613.1 - 0.027 14.3 0.5 0.046 13.6 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle RRM_1 PF00076.17 KNZ78616.1 - 4e-28 96.8 0.0 2.7e-16 58.9 0.0 5.0 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ78616.1 - 2.7e-16 59.2 1.1 8e-11 41.7 0.0 4.4 4 1 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ78616.1 - 1.2e-13 50.6 0.1 6.8e-10 38.6 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KNZ78616.1 - 4.8e-06 26.3 0.1 1.2e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 KNZ78616.1 - 0.0019 17.9 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RasGAP PF00616.14 KNZ78617.1 - 9.6e-26 90.6 0.0 3.3e-25 88.9 0.0 2.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 KNZ78617.1 - 8.2e-06 25.7 0.1 2.7e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain NYD-SP28_assoc PF14775.1 KNZ78618.1 - 0.014 15.0 5.9 0.26 11.0 0.6 3.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain HALZ PF02183.13 KNZ78618.1 - 0.016 14.9 0.9 0.016 14.9 0.6 4.1 3 1 1 4 4 4 0 Homeobox associated leucine zipper IncA PF04156.9 KNZ78618.1 - 3.2 7.3 38.2 1.3 8.6 4.1 3.6 1 1 2 3 3 3 0 IncA protein DivIVA PF05103.8 KNZ78618.1 - 6.4 6.8 26.3 5 7.1 2.1 3.6 2 1 1 3 3 3 0 DivIVA protein DivIC PF04977.10 KNZ78618.1 - 7.1 6.1 13.9 1.6 8.2 0.1 3.6 3 0 0 3 3 3 0 Septum formation initiator RGS PF00615.14 KNZ78619.1 - 5.8e-06 26.3 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF4131 PF13567.1 KNZ78619.1 - 0.011 15.1 0.1 0.023 14.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Tankyrase_bdg_C PF15327.1 KNZ78619.1 - 0.02 15.0 0.2 0.034 14.3 0.1 1.4 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain ATG22 PF11700.3 KNZ78621.1 - 1.7e-79 267.5 14.0 1.9e-79 267.3 9.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KNZ78621.1 - 2.1e-08 33.3 25.9 4.2e-06 25.7 8.4 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Got1 PF04178.7 KNZ78621.1 - 0.13 12.3 0.0 0.13 12.3 0.0 3.4 2 1 0 3 3 3 0 Got1/Sft2-like family SHOCT PF09851.4 KNZ78621.1 - 0.15 11.5 0.8 0.31 10.5 0.6 1.5 1 0 0 1 1 1 0 Short C-terminal domain Band_7 PF01145.20 KNZ78622.1 - 3.5e-17 62.8 8.0 1.4e-11 44.6 1.2 2.4 1 1 1 2 2 2 2 SPFH domain / Band 7 family SBP_bac_5 PF00496.17 KNZ78622.1 - 0.029 13.2 0.2 0.039 12.7 0.1 1.3 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle TroA PF01297.12 KNZ78622.1 - 0.039 13.1 0.2 0.085 12.0 0.1 1.5 1 1 0 1 1 1 0 Periplasmic solute binding protein family EVE PF01878.13 KNZ78623.1 - 6e-42 143.0 0.0 1.2e-41 142.1 0.0 1.5 1 0 0 1 1 1 1 EVE domain FAM176 PF14851.1 KNZ78623.1 - 2.7 7.6 5.7 4.4 6.9 3.9 1.3 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 KNZ78623.1 - 9.9 6.5 13.8 26 5.1 9.6 1.8 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Arrestin_N PF00339.24 KNZ78624.1 - 5.6e-09 35.9 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain GRAM PF02893.15 KNZ78625.1 - 2e-05 24.0 0.0 2.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.3 KNZ78625.1 - 0.0057 16.4 0.0 0.021 14.5 0.0 2.0 3 0 0 3 3 3 1 Vacuolar protein sorting protein 36 Vps36 DUF3433 PF11915.3 KNZ78627.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) Pkinase PF00069.20 KNZ78629.1 - 1.3e-39 135.9 0.0 1.2e-23 83.6 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ78629.1 - 1.4e-12 47.2 0.0 3.5e-09 36.1 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KNZ78629.1 - 0.0004 20.1 0.0 0.0012 18.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KNZ78629.1 - 0.041 12.8 0.0 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like UCH PF00443.24 KNZ78630.1 - 6.8e-33 113.9 0.0 9.7e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNZ78630.1 - 5e-06 26.1 0.0 9.4e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1992 PF09350.5 KNZ78632.1 - 8.3e-20 70.3 0.0 1.7e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Glyco_hydro_61 PF03443.9 KNZ78633.1 - 1.7e-61 207.8 0.3 2e-61 207.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ADH_zinc_N PF00107.21 KNZ78634.1 - 1e-14 54.1 0.0 1.6e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ78634.1 - 2.1e-09 37.1 0.0 3.4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DAGK_cat PF00781.19 KNZ78634.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Pro_isomerase PF00160.16 KNZ78635.1 - 3.6e-38 131.2 0.0 5.4e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KNZ78635.1 - 3e-16 58.8 0.0 7e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ78635.1 - 4.3e-12 45.8 0.0 1.1e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ78635.1 - 6.9e-08 32.2 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTB PF00651.26 KNZ78636.1 - 4.4e-14 52.3 0.0 8.4e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Stc1 PF12898.2 KNZ78636.1 - 0.025 14.6 0.2 0.062 13.3 0.1 1.6 1 1 0 1 1 1 0 Stc1 domain Aldedh PF00171.17 KNZ78637.1 - 3.8e-101 338.7 0.0 4.7e-101 338.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_12 PF01670.11 KNZ78638.1 - 1.6e-24 86.4 1.1 3.3e-24 85.4 0.8 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 DUF4470 PF14737.1 KNZ78639.1 - 7.7e-22 76.9 0.0 1.7e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 KNZ78639.1 - 2.4e-10 40.1 11.3 2.4e-10 40.1 7.8 2.2 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 KNZ78639.1 - 0.18 11.6 4.1 0.51 10.2 2.9 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.11 KNZ78639.1 - 0.2 11.3 7.5 0.45 10.2 5.2 1.6 1 0 0 1 1 1 0 HIT zinc finger Cullin PF00888.17 KNZ78640.1 - 6.3e-184 612.7 19.9 9.3e-184 612.2 13.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KNZ78640.1 - 1.5e-27 95.1 3.9 1.5e-27 95.1 2.7 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF1727 PF08353.5 KNZ78640.1 - 0.035 13.7 0.2 0.17 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1727) FACT-Spt16_Nlob PF14826.1 KNZ78640.1 - 0.039 13.4 0.2 0.039 13.4 0.2 3.4 3 1 0 3 3 3 0 FACT complex subunit SPT16 N-terminal lobe domain Rrf2 PF02082.15 KNZ78640.1 - 0.047 13.8 1.0 0.13 12.4 0.2 2.1 2 0 0 2 2 2 0 Transcriptional regulator MarR_2 PF12802.2 KNZ78640.1 - 0.051 13.2 0.1 8.7 6.0 0.0 3.1 3 0 0 3 3 3 0 MarR family WGG PF10273.4 KNZ78640.1 - 0.69 10.0 3.5 15 5.7 0.0 3.6 3 1 0 3 3 3 0 Pre-rRNA-processing protein TSR2 WD40 PF00400.27 KNZ78641.1 - 5.1e-41 137.1 5.6 2.2e-08 33.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KNZ78641.1 - 9.2e-05 22.2 0.0 0.032 13.9 0.0 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KNZ78641.1 - 0.00091 17.6 0.0 0.095 10.9 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 KNZ78641.1 - 0.0015 18.0 0.8 1.2 8.5 0.2 3.0 2 1 1 3 3 3 1 PQQ-like domain Me-amine-dh_H PF06433.6 KNZ78641.1 - 0.0032 16.1 0.0 0.01 14.4 0.0 1.9 2 1 0 2 2 2 1 Methylamine dehydrogenase heavy chain (MADH) DUF3312 PF11768.3 KNZ78641.1 - 0.011 13.9 0.0 0.056 11.6 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) PQQ_3 PF13570.1 KNZ78641.1 - 0.03 14.6 4.9 0.54 10.6 0.0 4.3 4 1 0 4 4 4 0 PQQ-like domain BBS2_N PF14781.1 KNZ78641.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Arb1 PF09692.5 KNZ78643.1 - 2.4e-06 26.6 0.0 4.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 RVP_2 PF08284.6 KNZ78644.1 - 0.14 12.1 0.0 1.2 9.1 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease RPAP3_C PF13877.1 KNZ78645.1 - 0.15 12.0 1.4 0.54 10.2 0.1 2.5 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 zf-CCHC PF00098.18 KNZ78651.1 - 0.03 14.2 0.4 0.03 14.2 0.3 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 KNZ78652.1 - 0.03 14.2 0.4 0.03 14.2 0.3 1.8 2 0 0 2 2 2 0 Zinc knuckle Helitron_like_N PF14214.1 KNZ78653.1 - 5.3e-62 208.8 0.1 7.6e-62 208.3 0.1 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 KNZ78653.1 - 0.021 13.5 0.0 0.046 12.4 0.0 1.3 1 1 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) DUF3296 PF11726.3 KNZ78653.1 - 0.031 13.8 0.0 0.081 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) ECH_C PF13766.1 KNZ78656.1 - 0.018 15.1 0.1 0.076 13.1 0.1 1.8 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region DUF485 PF04341.7 KNZ78657.1 - 0.93 9.2 6.1 0.55 9.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Glyco_hydro_16 PF00722.16 KNZ78660.1 - 2.8e-36 124.5 6.8 4.2e-36 123.9 4.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RRM_1 PF00076.17 KNZ78661.1 - 7.3e-22 76.7 0.0 1.8e-10 40.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ78661.1 - 1.3e-19 69.7 0.0 5e-10 39.0 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ78661.1 - 2.4e-17 62.6 0.0 7.4e-11 41.8 0.0 3.7 3 1 1 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KNZ78661.1 - 0.084 12.4 0.0 4.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Calcipressin Hydrophobin PF01185.13 KNZ78662.1 - 9.3e-17 61.2 12.1 1.3e-16 60.7 8.4 1.2 1 0 0 1 1 1 1 Fungal hydrophobin RNA_pol_L_2 PF13656.1 KNZ78663.1 - 1.7e-26 91.4 0.0 2e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KNZ78663.1 - 1.3e-08 33.8 0.0 1.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Chordopox_A33R PF05966.7 KNZ78663.1 - 0.043 12.5 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein DUF566 PF04484.7 KNZ78664.1 - 1.6 8.1 11.1 1.7 8.0 7.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Abhydrolase_6 PF12697.2 KNZ78665.1 - 4.9e-27 95.2 1.3 2.5e-26 92.9 0.9 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ78665.1 - 2.7e-17 63.1 0.2 5.8e-17 62.0 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ78665.1 - 4.1e-10 39.5 0.0 1.4e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KNZ78665.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 KNZ78665.1 - 0.0054 16.1 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.9 KNZ78665.1 - 0.0062 15.0 0.0 0.53 8.7 0.0 2.1 2 0 0 2 2 2 2 Ndr family Abhydrolase_8 PF06259.7 KNZ78665.1 - 0.035 13.6 0.3 0.068 12.6 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Peptidase_S9 PF00326.16 KNZ78665.1 - 0.044 12.9 0.1 1.7 7.8 0.0 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family RA PF00788.18 KNZ78666.1 - 1.6e-13 50.9 0.0 5.1e-10 39.7 0.0 3.2 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 KNZ78666.1 - 9.7e-06 24.8 0.0 2.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KNZ78666.1 - 0.00039 19.9 0.6 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain DSPc PF00782.15 KNZ78667.1 - 2.9e-27 94.8 0.0 4.1e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KNZ78667.1 - 0.00036 19.9 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3151 PF11349.3 KNZ78667.1 - 0.043 13.8 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3151) DDE_1 PF03184.14 KNZ78669.1 - 3.1e-13 49.3 0.2 3.3e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_hydro_25 PF01183.15 KNZ78670.1 - 2.3e-50 170.9 0.6 2.6e-50 170.7 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 DUF2855 PF11017.3 KNZ78671.1 - 8.6e-63 212.3 0.0 1e-62 212.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) PDEase_I PF00233.14 KNZ78672.1 - 3.5e-39 134.9 0.1 6.1e-35 121.0 0.0 2.1 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 KNZ78672.1 - 0.055 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 HD domain Helitron_like_N PF14214.1 KNZ78673.1 - 0.00065 19.4 0.3 0.00094 18.9 0.2 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Chromo PF00385.19 KNZ78674.1 - 3.7e-19 68.1 0.1 4.6e-19 67.8 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KNZ78674.1 - 0.066 12.9 0.6 0.087 12.5 0.4 1.3 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain SF3a60_bindingd PF12108.3 KNZ78674.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Mtf2_C PF14061.1 KNZ78674.1 - 0.1 12.5 0.2 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Sec23_trunk PF04811.10 KNZ78675.1 - 8.4e-44 149.7 0.0 1.4e-43 148.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KNZ78675.1 - 5.2e-20 70.8 0.3 1e-19 69.8 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 KNZ78675.1 - 2.5e-15 55.7 2.6 5.8e-15 54.5 1.8 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 KNZ78675.1 - 3.4e-13 49.9 0.3 6.9e-13 48.9 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KNZ78675.1 - 3.9e-07 29.6 0.0 7.5e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Mcp5_PH PF12814.2 KNZ78676.1 - 1.8e-41 140.8 0.3 5.8e-41 139.2 0.0 2.1 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology RCC1 PF00415.13 KNZ78676.1 - 0.095 12.9 0.0 0.34 11.1 0.0 2.0 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Aspzincin_M35 PF14521.1 KNZ78677.1 - 4.3e-18 66.2 0.1 1.2e-17 64.8 0.0 1.7 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 KNZ78677.1 - 0.0032 16.9 0.7 0.17 11.2 0.0 2.3 2 0 0 2 2 2 2 Putative peptidase family 2OG-FeII_Oxy_3 PF13640.1 KNZ78678.1 - 8e-05 23.0 0.1 0.00014 22.2 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KNZ78678.1 - 0.0072 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KNZ78679.1 - 8.8e-05 22.9 0.1 0.00018 21.9 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KNZ78679.1 - 0.0022 18.2 0.0 0.0049 17.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KNZ78680.1 - 8.5e-05 23.0 0.1 0.00017 22.0 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KNZ78680.1 - 0.0087 16.3 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 KNZ78681.1 - 6.6e-78 262.2 0.0 7.8e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SWIRM PF04433.12 KNZ78682.1 - 2.9e-35 120.2 0.0 2.1e-34 117.4 0.0 2.1 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 KNZ78682.1 - 2e-10 40.6 0.0 3.6e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KNZ78682.1 - 1.3e-09 37.9 0.1 3e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1192 PF06698.6 KNZ78683.1 - 0.1 12.3 1.6 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF3275 PF11679.3 KNZ78683.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) ArgJ PF01960.13 KNZ78684.1 - 3.2e-118 394.5 0.2 1e-94 317.1 0.5 2.0 2 0 0 2 2 2 2 ArgJ family DEAD PF00270.24 KNZ78685.1 - 1e-44 152.0 0.0 1.7e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ78685.1 - 1.4e-26 92.1 0.1 4.3e-26 90.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ78685.1 - 5.6e-06 26.3 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KNZ78685.1 - 0.016 15.3 0.2 0.094 12.8 0.2 2.3 1 1 0 1 1 1 0 AAA domain RNase_H PF00075.19 KNZ78687.1 - 0.0038 17.5 0.1 0.1 12.9 0.0 2.7 3 0 0 3 3 3 1 RNase H RRM_1 PF00076.17 KNZ78688.1 - 1.9e-49 165.1 0.0 1.5e-15 56.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ78688.1 - 4.6e-35 119.4 0.0 6.6e-12 45.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ78688.1 - 2.1e-21 75.4 0.0 1.1e-06 28.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KNZ78688.1 - 0.00028 20.5 0.0 0.021 14.5 0.0 3.4 3 1 0 3 3 3 1 Limkain b1 RRM_3 PF08777.6 KNZ78688.1 - 0.0013 18.5 0.0 4.5 7.1 0.0 3.3 3 0 0 3 3 3 1 RNA binding motif MIP-T3 PF10243.4 KNZ78688.1 - 0.0074 14.8 16.7 0.0093 14.4 11.6 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF3343 PF11823.3 KNZ78688.1 - 0.011 14.9 0.0 0.068 12.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3343) Methyltransf_2 PF00891.13 KNZ78689.1 - 7.3e-29 100.6 0.0 1.6e-28 99.5 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Tetraspannin PF00335.15 KNZ78689.1 - 6.1e-13 48.5 10.1 9.3e-13 47.9 7.0 1.3 1 0 0 1 1 1 1 Tetraspanin family SPC12 PF06645.8 KNZ78689.1 - 0.013 15.2 0.4 0.083 12.7 0.4 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Dimerisation PF08100.6 KNZ78689.1 - 0.022 14.5 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain FTR1 PF03239.9 KNZ78689.1 - 0.028 13.3 0.4 0.049 12.5 0.2 1.3 1 0 0 1 1 1 0 Iron permease FTR1 family RPA_C PF08784.6 KNZ78689.1 - 0.07 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Replication protein A C terminal HsbA PF12296.3 KNZ78690.1 - 5.9e-12 45.5 1.0 7.6e-12 45.1 0.3 1.3 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Ldh_1_C PF02866.13 KNZ78690.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.3 1 1 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain NAD_binding_9 PF13454.1 KNZ78692.1 - 3.6e-05 23.5 0.0 0.00014 21.6 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding zf-MYND PF01753.13 KNZ78693.1 - 6.8e-06 25.8 0.9 1.3e-05 24.9 0.6 1.5 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 KNZ78693.1 - 0.024 13.9 0.4 0.054 12.8 0.3 1.6 1 0 0 1 1 1 0 Life-span regulatory factor DUF2256 PF10013.4 KNZ78693.1 - 0.13 11.9 1.6 0.28 10.9 1.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) N6-adenineMlase PF10237.4 KNZ78694.1 - 3.6e-34 117.7 0.0 4.3e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase UPF0020 PF01170.13 KNZ78694.1 - 0.072 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Formyl_trans_N PF00551.14 KNZ78695.1 - 5.6e-37 127.0 0.0 8.7e-36 123.1 0.0 2.0 1 1 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.13 KNZ78695.1 - 0.019 14.5 0.1 0.027 14.0 0.1 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Pkinase PF00069.20 KNZ78696.1 - 2.8e-65 220.0 0.0 3.3e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ78696.1 - 2.8e-27 95.4 0.0 3.6e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ78696.1 - 2e-06 27.0 0.0 4.3e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KNZ78696.1 - 0.00027 20.3 0.1 0.00053 19.3 0.1 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 KNZ78696.1 - 0.00041 19.4 0.3 0.0011 18.1 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ78696.1 - 0.013 15.2 0.2 0.38 10.4 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sec62 PF03839.11 KNZ78697.1 - 7.1e-50 169.5 4.6 4.7e-49 166.8 2.8 2.0 2 0 0 2 2 2 1 Translocation protein Sec62 TPR_12 PF13424.1 KNZ78698.1 - 2.1e-08 33.9 7.0 0.059 13.3 0.5 4.8 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ78698.1 - 0.0001 21.8 5.2 0.59 9.8 0.0 4.0 4 1 1 5 5 5 2 TPR repeat TPR_7 PF13176.1 KNZ78698.1 - 0.00015 21.3 0.2 2.5 8.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF2225 PF09986.4 KNZ78698.1 - 0.017 14.6 0.5 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_2 PF07719.12 KNZ78698.1 - 0.13 12.2 8.3 1.4 9.0 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ78698.1 - 0.96 10.2 9.5 9 7.2 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ78698.1 - 6.1 7.5 7.2 0.74 10.4 0.2 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Ead_Ea22 PF13935.1 KNZ78699.1 - 0.0024 18.2 3.0 0.043 14.1 1.6 2.3 1 1 0 1 1 1 1 Ead/Ea22-like protein Macoilin PF09726.4 KNZ78699.1 - 0.0035 15.7 8.3 0.0043 15.3 5.8 1.0 1 0 0 1 1 1 1 Transmembrane protein CCDC92 PF14916.1 KNZ78699.1 - 0.0063 16.0 0.1 1.3 8.6 0.0 2.6 2 0 0 2 2 2 1 Coiled-coil domain of unknown function bZIP_1 PF00170.16 KNZ78699.1 - 0.018 14.9 6.8 1.2 9.1 0.5 3.3 2 1 1 3 3 3 0 bZIP transcription factor Ax_dynein_light PF10211.4 KNZ78699.1 - 0.02 14.7 3.5 0.02 14.7 2.5 1.9 2 1 0 2 2 2 0 Axonemal dynein light chain DUF603 PF04645.7 KNZ78699.1 - 0.032 14.1 0.1 0.069 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF603 HALZ PF02183.13 KNZ78699.1 - 0.037 13.7 0.9 0.037 13.7 0.6 3.1 4 0 0 4 4 3 0 Homeobox associated leucine zipper DUF3772 PF12607.3 KNZ78699.1 - 0.18 11.5 6.4 0.42 10.2 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3772) DivIVA PF05103.8 KNZ78699.1 - 0.34 10.9 7.2 2 8.4 0.9 2.4 1 1 0 2 2 2 0 DivIVA protein K-box PF01486.12 KNZ78699.1 - 0.6 9.9 10.6 0.27 11.0 0.5 3.0 2 2 1 3 3 3 0 K-box region bZIP_2 PF07716.10 KNZ78699.1 - 1.3 8.9 13.3 0.29 10.9 0.8 3.8 4 0 0 4 4 4 0 Basic region leucine zipper CENP-F_leu_zip PF10473.4 KNZ78699.1 - 2.2 8.1 9.8 0.16 11.8 1.8 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 KNZ78699.1 - 2.2 7.2 8.6 0.089 11.8 1.8 1.6 2 1 0 2 2 2 0 Autophagy protein Apg6 NUDE_C PF04880.8 KNZ78699.1 - 3.1 8.1 14.0 4.6 7.5 0.6 2.6 2 1 1 3 3 3 0 NUDE protein, C-terminal conserved region GAS PF13851.1 KNZ78699.1 - 3.5 6.7 9.1 1.8 7.6 3.3 2.3 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding NYD-SP28_assoc PF14775.1 KNZ78699.1 - 3.6 7.3 8.6 1.3 8.8 0.6 2.9 3 0 0 3 3 3 0 Sperm tail C-terminal domain Rab5-bind PF09311.6 KNZ78699.1 - 5.7 6.7 17.7 0.1 12.4 5.8 2.5 1 1 2 3 3 3 0 Rabaptin-like protein TBPIP PF07106.8 KNZ78699.1 - 5.8 6.4 6.6 0.83 9.1 1.3 1.9 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FUSC PF04632.7 KNZ78699.1 - 9.5 4.5 8.1 13 4.1 5.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Rad52_Rad22 PF04098.10 KNZ78700.1 - 1.2e-59 200.4 0.7 1.8e-59 199.8 0.0 1.6 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein Glu-tRNAGln PF02686.10 KNZ78700.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit HLH PF00010.21 KNZ78702.1 - 2.1e-08 33.6 0.0 1e-07 31.5 0.0 2.2 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Sec23_trunk PF04811.10 KNZ78703.1 - 2.8e-72 242.9 0.0 8.7e-72 241.3 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KNZ78703.1 - 1.1e-21 76.1 0.0 2.8e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KNZ78703.1 - 1.8e-18 66.8 0.0 4.6e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KNZ78703.1 - 6.9e-17 60.7 7.9 1.4e-16 59.7 5.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KNZ78703.1 - 4.6e-08 32.6 0.0 8.8e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.21 KNZ78703.1 - 4.7e-05 23.1 0.5 4.7e-05 23.1 0.3 2.4 2 0 0 2 2 2 1 WW domain CAP PF00188.21 KNZ78704.1 - 3.7e-23 82.3 0.1 4.8e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family XRCC4 PF06632.7 KNZ78704.1 - 0.098 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 ELYS PF13934.1 KNZ78706.1 - 9.1e-39 133.5 0.7 3.4e-38 131.6 0.5 1.8 1 1 0 1 1 1 1 Nuclear pore complex assembly ATP-synt_10 PF05176.9 KNZ78707.1 - 2.4e-16 59.7 0.1 3.6e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 ATP10 protein ACC_epsilon PF13822.1 KNZ78707.1 - 0.097 13.0 0.1 0.13 12.6 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Histone PF00125.19 KNZ78708.1 - 2.7e-26 91.4 0.0 3.4e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KNZ78708.1 - 3.4e-06 27.0 0.0 4.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Herpes_Helicase PF02689.9 KNZ78709.1 - 5.4e-05 21.1 0.1 5.4e-05 21.1 0.1 1.0 1 0 0 1 1 1 1 Helicase MFS_1 PF07690.11 KNZ78710.1 - 1.1e-40 139.4 44.8 1.8e-40 138.7 31.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ78710.1 - 6.1e-08 31.6 29.7 1.6e-07 30.3 20.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 KNZ78710.1 - 0.00092 17.4 4.0 0.00092 17.4 2.8 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector DUF4022 PF13214.1 KNZ78710.1 - 0.055 13.5 0.1 0.055 13.5 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4022) DUF563 PF04577.9 KNZ78711.1 - 9.7e-11 41.9 0.0 8.9e-10 38.8 0.0 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF563) Sugar_tr PF00083.19 KNZ78716.1 - 2.1e-95 319.9 15.3 2.7e-95 319.6 10.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ78716.1 - 2.4e-18 65.9 31.6 2.2e-13 49.6 8.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KNZ78716.1 - 0.00066 18.1 0.4 0.00066 18.1 0.3 3.5 2 1 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KNZ78716.1 - 0.0018 16.5 3.3 0.0042 15.3 0.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 KNZ78716.1 - 0.0029 16.3 0.8 0.0029 16.3 0.6 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF791) Atg14 PF10186.4 KNZ78717.1 - 0.035 13.0 0.5 0.056 12.3 0.0 1.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Sugar_tr PF00083.19 KNZ78718.1 - 2.4e-97 326.3 22.8 2.9e-97 326.0 15.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ78718.1 - 9.3e-21 73.9 32.6 1.8e-15 56.5 6.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KNZ78718.1 - 0.0015 16.8 1.0 0.0015 16.8 0.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.16 KNZ78719.1 - 5.7e-46 156.9 13.9 3.8e-45 154.2 9.5 2.3 2 1 0 2 2 2 1 POT family DUF1469 PF07332.6 KNZ78719.1 - 3.4 7.4 20.2 2 8.1 1.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1469) DDE_1 PF03184.14 KNZ78720.1 - 9e-19 67.4 0.3 1.2e-18 67.0 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PTR2 PF00854.16 KNZ78721.1 - 2.6e-43 148.2 17.3 1.8e-41 142.2 12.0 3.0 1 1 0 1 1 1 1 POT family Methyltransf_11 PF08241.7 KNZ78722.1 - 2.1e-18 66.5 0.0 4.8e-18 65.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ78722.1 - 7.2e-12 45.6 0.0 1.7e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ78722.1 - 2e-10 40.4 0.0 3.2e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ78722.1 - 2.9e-10 40.3 0.0 5.5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ78722.1 - 1.4e-08 35.2 0.0 3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ78722.1 - 1.9e-05 24.4 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNZ78722.1 - 2.1e-05 23.7 0.0 6.6e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KNZ78722.1 - 0.00023 20.5 0.0 0.00036 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KNZ78722.1 - 0.0011 18.9 0.0 0.0032 17.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KNZ78722.1 - 0.0092 15.0 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 KNZ78722.1 - 0.095 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 KNZ78722.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) LRR_4 PF12799.2 KNZ78723.1 - 0.025 14.1 4.7 7.5 6.2 0.2 4.7 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_2 PF07723.8 KNZ78723.1 - 0.096 13.2 0.4 1.2 9.7 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat MatE PF01554.13 KNZ78724.1 - 9.6e-38 129.3 24.3 2.2e-21 76.1 6.5 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KNZ78724.1 - 0.00014 21.6 6.0 0.00014 21.6 4.1 3.7 2 2 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain CobT PF06213.7 KNZ78728.1 - 0.057 12.5 8.7 0.074 12.1 6.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 KNZ78728.1 - 0.15 10.0 9.5 0.16 9.9 6.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.6 KNZ78728.1 - 0.16 10.9 10.2 0.19 10.6 7.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.7 KNZ78728.1 - 0.26 9.1 12.9 0.3 8.9 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_RNA_Pol_19 PF05320.7 KNZ78728.1 - 0.82 9.4 4.7 1.4 8.6 3.3 1.4 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit eIF-3c_N PF05470.7 KNZ78728.1 - 6.4 4.7 8.0 7.5 4.5 5.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sigma70_ner PF04546.8 KNZ78728.1 - 6.5 6.3 8.8 9.1 5.8 6.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.6 KNZ78728.1 - 9 4.0 11.0 11 3.7 7.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Chromo PF00385.19 KNZ78729.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Phosphoesterase PF04185.9 KNZ78730.1 - 9.9e-31 107.2 0.5 1.6e-30 106.5 0.4 1.4 1 0 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.18 KNZ78730.1 - 0.034 13.3 0.1 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Sulfatase Transaldolase PF00923.14 KNZ78731.1 - 1.4e-94 316.5 0.0 1.5e-94 316.3 0.0 1.0 1 0 0 1 1 1 1 Transaldolase GST_N_3 PF13417.1 KNZ78732.1 - 9.6e-09 35.3 0.2 2.3e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KNZ78732.1 - 2.8e-06 27.2 0.1 5e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KNZ78732.1 - 0.0044 16.8 3.1 0.007 16.2 0.2 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KNZ78732.1 - 0.062 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KNZ78732.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AhpC-TSA PF00578.16 KNZ78734.1 - 1.4e-25 89.3 0.0 1.9e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KNZ78734.1 - 5.4e-15 55.1 0.0 7.8e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin HMG14_17 PF01101.13 KNZ78734.1 - 0.00044 20.8 7.8 0.00079 20.0 5.4 1.4 1 0 0 1 1 1 1 HMG14 and HMG17 AhpC-TSA_2 PF13911.1 KNZ78734.1 - 0.077 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme LRR_6 PF13516.1 KNZ78735.1 - 1.6e-11 42.9 20.7 0.11 12.6 0.3 8.5 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.2 KNZ78735.1 - 5.2e-09 35.5 28.0 0.00084 18.8 0.3 6.5 3 2 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KNZ78735.1 - 6.4e-05 22.4 18.7 4.1 7.8 0.5 9.0 7 3 2 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.1 KNZ78735.1 - 0.0006 19.5 26.4 0.0081 15.8 1.8 6.1 4 3 2 6 6 6 3 Leucine rich repeat GAT PF03127.9 KNZ78735.1 - 0.0013 18.6 0.2 0.0032 17.4 0.1 1.6 1 0 0 1 1 1 1 GAT domain LRR_7 PF13504.1 KNZ78735.1 - 0.15 12.3 27.0 4.3 7.9 0.1 9.0 10 0 0 10 10 10 0 Leucine rich repeat Peptidase_M14 PF00246.19 KNZ78736.1 - 3.7e-51 174.3 0.0 4.2e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase SKN1 PF03935.10 KNZ78737.1 - 7.4e-38 129.9 0.0 2.6e-32 111.6 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Esterase_phd PF10503.4 KNZ78738.1 - 2.2e-23 82.6 0.9 3.1e-23 82.1 0.6 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KNZ78738.1 - 1e-09 37.9 0.5 1.7e-09 37.2 0.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KNZ78738.1 - 4.9e-07 29.6 0.2 6.2e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ78738.1 - 6.1e-06 26.2 0.1 8.2e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KNZ78738.1 - 8.5e-05 22.0 0.6 0.00018 21.0 0.4 1.7 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.7 KNZ78738.1 - 0.029 12.8 0.0 0.044 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 KNZ78739.1 - 7.4e-24 84.2 0.7 1.1e-23 83.6 0.5 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KNZ78739.1 - 3.2e-09 36.3 0.5 4.6e-09 35.8 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KNZ78739.1 - 5.4e-07 29.4 0.2 7.4e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family CBM_1 PF00734.13 KNZ78739.1 - 1.2e-06 28.0 6.3 1.2e-06 28.0 4.4 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain Esterase PF00756.15 KNZ78739.1 - 2.6e-06 27.0 0.6 1.3e-05 24.8 0.4 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 KNZ78739.1 - 3.1e-05 23.9 0.1 4.4e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KNZ78739.1 - 0.019 13.5 0.0 0.03 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Sporozoite_P67 PF05642.6 KNZ78739.1 - 0.45 8.3 5.1 0.58 7.9 3.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_C54 PF03416.14 KNZ78740.1 - 8.5e-87 290.8 0.0 1.2e-86 290.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 zf-CCHC PF00098.18 KNZ78741.1 - 0.034 14.0 0.6 0.057 13.3 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.1 KNZ78742.1 - 2.7e-06 27.7 0.0 6.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ78742.1 - 0.0036 16.8 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease NSP10 PF09401.5 KNZ78742.1 - 0.084 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA synthesis protein NSP10 SVWC PF15430.1 KNZ78744.1 - 0.16 12.4 2.2 2.3 8.7 0.1 2.3 2 1 0 2 2 2 0 Single domain von Willebrand factor type C EFG_C PF00679.19 KNZ78745.1 - 1.8e-14 53.3 0.0 3.4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU PF00009.22 KNZ78745.1 - 0.0002 20.8 0.0 0.021 14.2 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 KNZ78745.1 - 0.01 15.9 0.3 0.025 14.6 0.2 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 RHSP PF07999.6 KNZ78745.1 - 0.12 10.9 0.1 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein UBN2_3 PF14244.1 KNZ78746.1 - 5.7e-09 35.7 0.1 7.8e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ78746.1 - 0.00093 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KNZ78746.1 - 0.0042 16.6 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type AAA_22 PF13401.1 KNZ78747.1 - 1.6e-08 34.7 0.4 8e-08 32.4 0.0 2.3 3 1 1 4 4 4 1 AAA domain NB-ARC PF00931.17 KNZ78747.1 - 1.4e-07 30.6 0.0 2.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KNZ78747.1 - 0.0001 22.3 0.1 0.001 19.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.24 KNZ78747.1 - 0.00048 20.3 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KNZ78747.1 - 0.035 13.3 0.0 0.078 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 KNZ78747.1 - 0.04 14.2 0.1 0.35 11.1 0.0 2.5 3 0 0 3 3 3 0 ABC transporter NAD_Gly3P_dh_N PF01210.18 KNZ78747.1 - 0.079 12.6 1.0 7 6.3 0.0 3.1 2 1 1 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MMR_HSR1 PF01926.18 KNZ78747.1 - 0.087 12.7 1.6 0.28 11.1 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.16 KNZ78747.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 KNZ78748.1 - 2.1e-08 34.3 0.0 5.6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KNZ78748.1 - 5.2e-07 28.8 0.0 9.3e-07 27.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KNZ78748.1 - 2.4e-05 24.4 0.1 0.00025 21.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.24 KNZ78748.1 - 0.0068 16.6 0.0 0.017 15.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KNZ78748.1 - 0.066 13.1 0.3 1.3 9.0 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 KNZ78748.1 - 0.069 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 KNZ78748.1 - 0.087 13.1 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter GTP_EFTU_D2 PF03144.20 KNZ78749.1 - 1.1e-07 31.8 1.5 1.9e-07 31.0 1.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 zf-CCHC_6 PF15288.1 KNZ78751.1 - 0.058 13.0 1.2 0.12 12.0 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Aldedh PF00171.17 KNZ78752.1 - 6.9e-27 93.9 2.1 5.2e-20 71.2 0.2 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family TPR_12 PF13424.1 KNZ78753.1 - 2.2e-08 33.8 7.8 0.0016 18.3 0.2 4.7 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ78753.1 - 1.5e-07 30.7 10.7 1.4 9.0 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat AAA_22 PF13401.1 KNZ78753.1 - 7.1e-07 29.4 0.1 4.4e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KNZ78753.1 - 3.3e-06 26.1 0.0 7.2e-06 25.0 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KNZ78753.1 - 6.4e-05 23.0 0.6 0.0005 20.1 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain TPR_16 PF13432.1 KNZ78753.1 - 0.00021 21.8 4.2 7.6 7.3 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat AAA PF00004.24 KNZ78753.1 - 0.001 19.2 0.4 0.004 17.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TPR_11 PF13414.1 KNZ78753.1 - 0.0029 17.2 5.0 1.7 8.3 0.0 4.4 3 1 0 4 4 4 2 TPR repeat TPR_8 PF13181.1 KNZ78753.1 - 0.0044 16.7 2.9 12 6.0 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ78753.1 - 0.0062 17.0 2.9 44 5.1 0.0 5.9 7 0 0 7 7 5 0 Tetratricopeptide repeat ARPC4 PF05856.7 KNZ78753.1 - 0.028 13.8 0.6 0.072 12.4 0.0 1.9 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) Dicty_CAD PF05720.7 KNZ78753.1 - 0.042 13.4 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 Cell-cell adhesion domain RepA_C PF04796.7 KNZ78753.1 - 0.074 12.6 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Plasmid encoded RepA protein TPR_1 PF00515.23 KNZ78753.1 - 0.077 12.6 0.4 38 4.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF258 PF03193.11 KNZ78753.1 - 0.13 11.3 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TPR_10 PF13374.1 KNZ78753.1 - 0.18 11.7 3.9 15 5.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ78753.1 - 1.7 9.0 6.3 2.4 8.5 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Aldedh PF00171.17 KNZ78754.1 - 2.9e-09 35.8 0.1 3.9e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA_22 PF13401.1 KNZ78754.1 - 2.3e-08 34.2 0.0 4.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KNZ78754.1 - 1.3e-06 27.4 0.0 2.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KNZ78754.1 - 2.1e-05 24.5 0.2 0.00023 21.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.24 KNZ78754.1 - 0.0052 16.9 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KNZ78754.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KNZ78754.1 - 0.031 14.2 0.5 0.07 13.0 0.2 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KNZ78754.1 - 0.056 13.7 0.2 0.2 11.9 0.0 1.9 1 1 1 2 2 2 0 ABC transporter Miro PF08477.8 KNZ78754.1 - 0.061 13.8 0.0 0.16 12.4 0.0 1.8 2 0 0 2 2 1 0 Miro-like protein AAA_14 PF13173.1 KNZ78754.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 KNZ78754.1 - 0.074 11.9 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KNZ78754.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KNZ78754.1 - 0.12 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KNZ78754.1 - 0.13 13.0 0.0 0.24 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain GTP_EFTU_D2 PF03144.20 KNZ78755.1 - 4.9e-05 23.3 1.3 9.1e-05 22.5 0.9 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RVP_2 PF08284.6 KNZ78756.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KNZ78758.1 - 0.0014 19.0 0.0 0.0028 18.1 0.0 1.5 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.5 KNZ78758.1 - 0.027 14.0 0.1 0.11 12.1 0.0 1.8 1 1 1 2 2 2 0 Aspartyl protease zf-CCHC PF00098.18 KNZ78759.1 - 0.01 15.7 0.5 0.019 14.9 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle KRAB PF01352.22 KNZ78759.1 - 0.56 9.7 2.9 2.3 7.7 0.1 2.8 2 1 1 3 3 3 0 KRAB box UBN2_3 PF14244.1 KNZ78760.1 - 1.1e-08 34.8 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KNZ78760.1 - 0.0015 18.0 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ78760.1 - 0.0058 16.4 0.0 0.0077 16.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KNZ78761.1 - 1.8e-08 34.0 0.0 2.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KNZ78761.1 - 0.00014 21.4 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ78761.1 - 0.00057 19.6 0.0 0.00087 19.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type EFG_C PF00679.19 KNZ78762.1 - 9.4e-15 54.2 0.0 1.6e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KNZ78762.1 - 0.029 14.4 0.5 0.07 13.2 0.4 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 SYCE1 PF15233.1 KNZ78766.1 - 0.015 15.2 3.1 0.023 14.6 2.2 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 YscO PF07321.7 KNZ78766.1 - 0.026 14.3 1.8 0.035 13.9 1.2 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO BLOC1_2 PF10046.4 KNZ78766.1 - 0.086 12.9 1.7 0.13 12.4 0.8 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.7 KNZ78766.1 - 0.1 12.3 7.0 0.76 9.5 5.1 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Sipho_Gp157 PF05565.6 KNZ78766.1 - 0.14 11.7 4.2 0.18 11.3 2.9 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 DUF3560 PF12083.3 KNZ78766.1 - 0.15 12.0 3.2 0.17 11.9 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3560) CENP-F_leu_zip PF10473.4 KNZ78766.1 - 0.22 11.3 6.0 0.3 10.9 4.2 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 KNZ78766.1 - 0.38 10.7 5.9 0.19 11.7 1.0 2.2 2 0 0 2 2 2 0 bZIP transcription factor COX16 PF14138.1 KNZ78766.1 - 2.9 8.1 6.1 11 6.3 1.7 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein COX16 BBP1_C PF15272.1 KNZ78767.1 - 0.0046 16.5 8.5 0.006 16.1 5.9 1.2 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal DUF2968 PF11180.3 KNZ78767.1 - 0.0048 16.2 5.4 0.0068 15.8 3.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Tropomyosin_1 PF12718.2 KNZ78767.1 - 0.016 15.0 13.4 0.016 15.0 9.3 1.7 2 1 0 2 2 2 0 Tropomyosin like DUF1664 PF07889.7 KNZ78767.1 - 0.084 12.6 3.5 0.12 12.1 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.8 KNZ78767.1 - 0.11 13.2 6.0 0.16 12.6 4.1 1.4 1 1 0 1 1 1 0 Occludin homology domain APG6 PF04111.7 KNZ78767.1 - 0.2 10.6 10.7 0.25 10.3 7.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3166 PF11365.3 KNZ78767.1 - 0.47 10.9 5.7 0.24 11.8 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) DUF972 PF06156.8 KNZ78767.1 - 0.49 10.7 11.7 0.17 12.2 4.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF465 PF04325.8 KNZ78767.1 - 2.8 7.6 7.5 0.49 10.1 0.8 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF465) Fib_alpha PF08702.5 KNZ78767.1 - 8.8 6.4 8.9 5.1 7.2 2.8 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family p450 PF00067.17 KNZ78768.1 - 2.4e-46 158.2 0.1 3.1e-23 82.0 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 Asp_protease_2 PF13650.1 KNZ78770.1 - 1.9e-06 28.2 0.1 3.6e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.5 KNZ78770.1 - 0.01 15.4 0.1 0.017 14.7 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease rve PF00665.21 KNZ78771.1 - 0.0044 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_4 PF13613.1 KNZ78772.1 - 0.21 11.1 0.3 11 5.7 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease PIF1 PF05970.9 KNZ78775.1 - 3e-20 72.4 0.0 3.3e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase p450 PF00067.17 KNZ78776.1 - 8.7e-56 189.3 0.0 1.1e-55 188.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Asp_protease_2 PF13650.1 KNZ78777.1 - 0.033 14.6 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease ArdA PF07275.6 KNZ78778.1 - 0.023 14.9 0.5 0.025 14.8 0.3 1.1 1 0 0 1 1 1 0 Antirestriction protein (ArdA) SPT2 PF08243.6 KNZ78778.1 - 0.31 11.3 9.2 0.52 10.6 6.4 1.3 1 0 0 1 1 1 0 SPT2 chromatin protein Med1 PF10744.4 KNZ78782.1 - 0.12 11.1 0.2 1.1 8.0 0.0 2.5 4 0 0 4 4 4 0 Mediator of RNA polymerase II transcription subunit 1 Raptor_N PF14538.1 KNZ78783.1 - 0.092 12.5 0.3 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Bac_surface_Ag PF01103.18 KNZ78784.1 - 4.8e-41 141.2 0.1 6.2e-41 140.9 0.1 1.1 1 0 0 1 1 1 1 Surface antigen Palm_thioest PF02089.10 KNZ78785.1 - 3.2e-39 134.5 0.0 8.1e-39 133.2 0.0 1.5 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 KNZ78785.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Nucleos_tra2_C PF07662.8 KNZ78786.1 - 1.6e-65 220.5 4.4 1.6e-65 220.5 3.0 2.4 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KNZ78786.1 - 4.1e-19 68.7 2.6 4.1e-19 68.7 1.8 3.2 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 KNZ78786.1 - 1.8 8.4 14.1 0.54 10.1 2.4 3.4 2 1 0 2 2 2 0 Nucleoside recognition WD40 PF00400.27 KNZ78787.1 - 3.2e-21 74.3 3.6 2e-06 27.4 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat RPA_interact_C PF14768.1 KNZ78788.1 - 0.042 14.2 0.1 0.064 13.6 0.1 1.2 1 0 0 1 1 1 0 Replication protein A interacting C-terminal MPC PF03650.8 KNZ78790.1 - 7.6e-34 116.2 1.8 2.7e-31 107.9 0.3 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0041) DUF3421 PF11901.3 KNZ78791.1 - 2e-18 66.2 0.7 9.1e-11 41.5 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF3421) CBM_5_12 PF02839.9 KNZ78791.1 - 0.00011 21.6 1.2 0.00035 20.0 0.9 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain DUF4234 PF14018.1 KNZ78792.1 - 0.034 13.8 6.1 3.6 7.3 2.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) Kei1 PF08552.6 KNZ78792.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.9 2 1 1 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 Tetraspannin PF00335.15 KNZ78792.1 - 0.71 9.1 23.2 4.3 6.5 16.1 1.9 1 1 0 1 1 1 0 Tetraspanin family DsbB PF02600.11 KNZ78792.1 - 8.4 6.1 10.7 3.9 7.2 0.2 2.8 1 1 2 3 3 3 0 Disulfide bond formation protein DsbB COG5 PF10392.4 KNZ78794.1 - 1.2e-05 25.3 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 ALS_ss_C PF10369.4 KNZ78796.1 - 2.2e-22 78.5 0.2 8.8e-21 73.4 0.1 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 KNZ78796.1 - 2.3e-12 46.1 0.1 4.7e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KNZ78796.1 - 1.5e-08 34.3 0.0 3.6e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 KNZ78796.1 - 0.13 12.0 0.4 15 5.4 0.0 2.4 2 0 0 2 2 2 0 ACT domain HMG_box PF00505.14 KNZ78797.1 - 4.5e-07 30.0 0.8 4.5e-07 30.0 0.6 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box Tmemb_161AB PF10268.4 KNZ78797.1 - 0.13 10.7 0.2 0.17 10.3 0.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB RRM_1 PF00076.17 KNZ78798.1 - 4.3e-11 42.2 0.0 5.6e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ78798.1 - 1.1e-08 34.9 0.0 1.3e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ78798.1 - 4.7e-08 32.7 0.0 6.2e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.22 KNZ78799.1 - 1.2e-33 116.2 0.0 2.8e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KNZ78799.1 - 4.1e-31 108.4 3.5 5.9e-31 107.8 2.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KNZ78799.1 - 2.1e-07 31.2 0.1 0.0016 18.4 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KNZ78799.1 - 1.1e-05 25.4 0.0 2.8e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 KNZ78799.1 - 1.2e-05 24.6 0.5 0.00029 20.1 0.4 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KNZ78799.1 - 0.00041 19.8 0.4 0.00094 18.6 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KNZ78799.1 - 0.0019 18.3 0.4 0.018 15.1 0.3 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KNZ78799.1 - 0.055 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KNZ78799.1 - 0.068 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 KNZ78799.1 - 0.071 12.9 0.5 1.8 8.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_25 PF13481.1 KNZ78799.1 - 0.11 11.9 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KNZ78799.1 - 0.11 13.3 0.0 0.28 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KNZ78799.1 - 0.13 12.1 0.3 1.1 9.1 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NAD_kinase PF01513.16 KNZ78801.1 - 4.9e-71 238.8 0.0 8.9e-71 237.9 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase DUF2419 PF10343.4 KNZ78802.1 - 0.00027 20.3 0.0 0.0017 17.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2419) YqeY PF09424.5 KNZ78803.1 - 1.3e-12 47.8 0.0 1.4e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Yqey-like protein TEX12 PF15219.1 KNZ78803.1 - 0.11 12.4 0.2 0.41 10.6 0.0 2.1 1 1 1 2 2 2 0 Testis-expressed 12 zf-rbx1 PF12678.2 KNZ78804.1 - 1.1e-14 54.2 2.6 1.9e-14 53.5 1.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KNZ78804.1 - 3.5e-10 39.5 10.3 3.5e-10 39.5 7.1 2.5 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KNZ78804.1 - 1e-07 31.4 1.5 2.6e-07 30.1 1.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ78804.1 - 6.4e-06 26.0 2.7 6.4e-06 26.0 1.8 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNZ78804.1 - 6.6e-06 25.7 8.0 2.5e-05 23.8 1.1 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ78804.1 - 3.6e-05 23.4 4.8 0.00014 21.5 3.5 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KNZ78804.1 - 0.00018 21.2 5.3 0.00055 19.7 3.7 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KNZ78804.1 - 0.00048 19.7 8.6 0.00083 19.0 3.0 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KNZ78804.1 - 0.011 15.6 2.2 0.011 15.6 1.5 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KNZ78804.1 - 0.027 14.4 0.7 0.057 13.3 0.5 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KNZ78804.1 - 0.91 9.1 3.4 0.58 9.7 0.9 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Amidohydro_3 PF07969.6 KNZ78805.1 - 2.8e-75 254.0 0.1 3.3e-75 253.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KNZ78805.1 - 5.8e-09 36.3 3.5 0.0014 18.7 0.0 2.7 4 0 0 4 4 4 2 Amidohydrolase Amidohydro_1 PF01979.15 KNZ78805.1 - 5.9e-07 29.4 0.0 0.0042 16.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KNZ78805.1 - 0.00058 19.6 0.0 0.0017 18.1 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase SNF2_N PF00176.18 KNZ78806.1 - 1.4e-57 194.7 0.0 2.1e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNZ78806.1 - 2.2e-11 43.4 0.0 4.5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KNZ78806.1 - 2.9e-07 29.5 0.2 7.4e-07 28.2 0.1 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KNZ78806.1 - 2.6e-05 24.1 0.0 0.00017 21.4 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_M22 PF00814.20 KNZ78807.1 - 1.4e-68 231.3 0.0 1.6e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family YycC PF14174.1 KNZ78807.1 - 0.016 14.9 0.5 0.031 13.9 0.4 1.4 1 0 0 1 1 1 0 YycC-like protein HbrB PF08539.6 KNZ78808.1 - 3.7e-36 124.3 0.0 5e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 HbrB-like Dynamitin PF04912.9 KNZ78809.1 - 1.2e-24 86.9 5.1 6.3e-24 84.4 0.2 2.5 2 1 0 2 2 2 1 Dynamitin Laminin_II PF06009.7 KNZ78809.1 - 0.0025 17.5 0.2 0.019 14.7 0.0 2.4 2 0 0 2 2 2 1 Laminin Domain II DUF3584 PF12128.3 KNZ78809.1 - 0.0074 13.6 1.8 0.094 10.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) EzrA PF06160.7 KNZ78809.1 - 0.01 14.0 0.3 1.1 7.3 0.3 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA AIP3 PF03915.8 KNZ78809.1 - 0.01 14.7 1.1 0.015 14.2 0.2 1.6 2 0 0 2 2 2 0 Actin interacting protein 3 Syntaxin-6_N PF09177.6 KNZ78809.1 - 0.024 15.0 0.8 0.54 10.6 0.0 3.0 3 1 0 3 3 3 0 Syntaxin 6, N-terminal DUF935 PF06074.7 KNZ78809.1 - 0.031 12.9 1.6 0.069 11.8 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF935) phiKZ_IP PF12699.2 KNZ78809.1 - 0.11 11.4 1.6 3.7 6.3 0.3 2.6 2 0 0 2 2 2 0 phiKZ-like phage internal head proteins TPR_MLP1_2 PF07926.7 KNZ78809.1 - 0.15 11.8 5.2 0.21 11.3 0.2 2.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 KNZ78809.1 - 0.15 12.2 2.6 11 6.2 0.0 3.3 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MscS_porin PF12795.2 KNZ78809.1 - 0.44 9.8 16.8 7.4 5.8 6.2 3.3 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain COG2 PF06148.6 KNZ78809.1 - 0.5 10.2 5.4 2.8 7.8 0.2 3.4 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 KNZ78809.1 - 0.58 9.7 13.2 8.8 5.8 4.9 3.2 2 1 1 3 3 3 0 IncA protein DUF2968 PF11180.3 KNZ78809.1 - 0.88 8.9 11.1 4.8 6.5 4.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) BCAS2 PF05700.6 KNZ78809.1 - 1.4 8.2 7.8 15 4.9 2.2 3.1 2 1 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) Fmp27_WPPW PF10359.4 KNZ78809.1 - 4.6 5.5 7.7 4.7 5.5 0.5 2.8 1 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain DUF1192 PF06698.6 KNZ78809.1 - 6.5 6.6 9.4 2.8 7.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) MFS_1 PF07690.11 KNZ78811.1 - 2.9e-12 45.9 38.1 4e-12 45.5 26.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phos_pyr_kin PF08543.7 KNZ78812.1 - 3.4e-09 36.2 0.0 6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KNZ78812.1 - 2.5e-06 26.8 0.9 0.00018 20.7 0.0 2.9 3 0 0 3 3 3 1 pfkB family carbohydrate kinase 4HBT_2 PF13279.1 KNZ78814.1 - 1.9e-14 54.1 0.0 3.1e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KNZ78814.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 KNZ78814.1 - 0.0024 16.8 0.0 0.012 14.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-ACP thioesterase HSF_DNA-bind PF00447.12 KNZ78815.1 - 2.9e-31 107.6 0.2 3.5e-31 107.4 0.2 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding DUF3894 PF13033.1 KNZ78815.1 - 0.52 10.3 1.7 9.8 6.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3894) Syndecan PF01034.15 KNZ78817.1 - 0.027 14.1 0.1 0.054 13.1 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain DUF4293 PF14126.1 KNZ78818.1 - 1.5 8.7 5.3 6.9 6.5 3.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) START PF01852.14 KNZ78822.1 - 1.3e-10 40.9 0.1 1.1e-06 28.1 0.0 3.5 3 0 0 3 3 3 2 START domain RVP_2 PF08284.6 KNZ78824.1 - 0.04 13.8 0.0 0.051 13.5 0.0 1.3 1 1 0 1 1 1 0 Retroviral aspartyl protease IPK PF03770.11 KNZ78825.1 - 2.1e-41 141.7 0.0 3.1e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Nucleoplasmin PF03066.10 KNZ78825.1 - 0.073 12.5 2.3 0.12 11.8 1.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KNZ78825.1 - 0.16 12.2 3.6 0.3 11.3 2.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RmuC PF02646.11 KNZ78827.1 - 0.097 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 RmuC family Syndecan PF01034.15 KNZ78828.1 - 0.061 12.9 0.3 0.17 11.5 0.2 1.7 1 0 0 1 1 1 0 Syndecan domain Macoilin PF09726.4 KNZ78828.1 - 0.065 11.5 5.1 0.079 11.2 3.6 1.1 1 0 0 1 1 1 0 Transmembrane protein PAP1 PF08601.5 KNZ78828.1 - 0.67 9.5 17.0 1.1 8.8 11.7 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 SOG2 PF10428.4 KNZ78828.1 - 3.5 6.1 17.6 5.1 5.6 12.2 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Tim54 PF11711.3 KNZ78828.1 - 7.4 5.0 7.1 12 4.3 4.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SKG6 PF08693.5 KNZ78829.1 - 0.029 13.6 0.1 0.029 13.6 0.1 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF2453 PF10507.4 KNZ78829.1 - 0.081 12.7 0.1 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2453) CAP_GLY PF01302.20 KNZ78830.1 - 3.4e-27 93.9 0.4 5.7e-27 93.2 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KNZ78830.1 - 6.2e-25 87.2 0.0 1.7e-24 85.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.18 KNZ78830.1 - 0.0023 17.2 0.0 0.0087 15.4 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family AAA PF00004.24 KNZ78831.1 - 6.3e-79 262.6 0.1 4.7e-47 159.4 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KNZ78831.1 - 3e-21 75.1 1.4 2.4e-20 72.2 0.4 2.7 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 KNZ78831.1 - 1.5e-13 50.3 0.0 1.5e-05 24.2 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KNZ78831.1 - 2e-13 51.1 0.0 0.00013 22.7 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KNZ78831.1 - 1.3e-11 44.5 0.0 2.4e-05 24.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KNZ78831.1 - 1.9e-11 44.2 0.1 0.0017 18.4 0.0 4.9 3 2 0 3 3 3 2 AAA domain CDC48_2 PF02933.12 KNZ78831.1 - 8e-11 41.4 0.0 1.6e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.9 KNZ78831.1 - 9.2e-11 41.6 0.1 0.00021 21.0 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KNZ78831.1 - 1.2e-10 41.5 0.0 9.5e-05 22.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KNZ78831.1 - 3.4e-09 36.9 0.0 0.0023 17.9 0.0 3.2 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 KNZ78831.1 - 3.5e-09 35.8 0.0 0.0017 17.1 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 KNZ78831.1 - 2.7e-08 33.4 0.0 0.0042 16.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 KNZ78831.1 - 3.5e-08 33.4 0.0 0.0066 16.3 0.0 3.5 4 0 0 4 4 4 2 AAA domain Zeta_toxin PF06414.7 KNZ78831.1 - 2.7e-07 29.9 0.0 0.025 13.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 KNZ78831.1 - 3.6e-07 29.5 0.4 0.024 13.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KNZ78831.1 - 3.7e-07 29.7 1.8 0.009 15.7 0.0 2.9 3 0 0 3 3 2 2 Part of AAA domain Vps4_C PF09336.5 KNZ78831.1 - 7.1e-07 29.0 0.1 8.2e-06 25.6 0.0 2.6 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.17 KNZ78831.1 - 1.2e-06 28.6 0.0 0.019 15.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 KNZ78831.1 - 2.1e-06 28.0 0.0 0.031 14.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KNZ78831.1 - 5.1e-06 26.5 0.0 0.098 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 KNZ78831.1 - 9.2e-06 24.7 0.1 0.0088 14.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 KNZ78831.1 - 2.5e-05 24.2 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 KNZ78831.1 - 2.6e-05 23.8 0.0 0.096 12.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 KNZ78831.1 - 2.9e-05 23.6 0.0 0.44 10.0 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KNZ78831.1 - 4e-05 23.6 0.0 0.18 11.8 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 KNZ78831.1 - 4.3e-05 22.8 0.2 0.27 10.4 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_25 PF13481.1 KNZ78831.1 - 5.7e-05 22.5 2.3 0.021 14.2 0.0 3.6 2 2 1 4 4 4 1 AAA domain KaiC PF06745.8 KNZ78831.1 - 0.00019 20.6 0.1 0.75 8.8 0.0 2.6 2 0 0 2 2 2 2 KaiC DUF815 PF05673.8 KNZ78831.1 - 0.00019 20.4 0.0 0.017 14.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 KNZ78831.1 - 0.0002 20.9 0.0 0.54 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KNZ78831.1 - 0.00022 20.3 0.0 0.39 9.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 KNZ78831.1 - 0.00033 20.9 0.0 0.18 12.0 0.0 3.1 2 1 0 2 2 2 1 ABC transporter Viral_helicase1 PF01443.13 KNZ78831.1 - 0.0006 19.4 0.0 0.22 11.0 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 KNZ78831.1 - 0.0007 19.2 0.0 1.5 8.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KNZ78831.1 - 0.0013 18.2 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KNZ78831.1 - 0.0015 17.5 0.0 0.096 11.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.7 KNZ78831.1 - 0.0021 17.7 0.1 0.66 9.6 0.0 3.0 4 0 0 4 4 2 1 NACHT domain Arch_ATPase PF01637.13 KNZ78831.1 - 0.0024 17.6 0.0 3.1 7.4 0.0 3.1 2 1 0 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 KNZ78831.1 - 0.0048 15.7 0.0 0.35 9.6 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 KNZ78831.1 - 0.0066 16.1 0.6 1.8 8.2 0.0 3.7 4 0 0 4 4 4 1 NTPase Molydop_binding PF01568.16 KNZ78831.1 - 0.0094 15.7 0.0 0.029 14.2 0.0 1.7 1 1 0 1 1 1 1 Molydopterin dinucleotide binding domain Bac_DnaA PF00308.13 KNZ78831.1 - 0.011 15.3 0.0 0.8 9.3 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_10 PF12846.2 KNZ78831.1 - 0.015 14.7 2.6 6.9 6.0 0.0 4.2 4 1 0 5 5 4 0 AAA-like domain UFD1 PF03152.9 KNZ78831.1 - 0.02 14.0 0.0 0.055 12.6 0.0 1.6 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 IPT PF01745.11 KNZ78831.1 - 0.03 13.5 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 KNZ78831.1 - 0.04 13.5 0.1 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 KNZ78831.1 - 0.042 13.3 0.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.17 KNZ78831.1 - 0.049 13.4 0.8 3.7 7.3 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase KAP_NTPase PF07693.9 KNZ78831.1 - 0.053 12.4 0.0 1.2 8.0 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain KTI12 PF08433.5 KNZ78831.1 - 0.14 11.3 0.0 12 5.0 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PIF1 PF05970.9 KNZ78831.1 - 0.2 10.5 0.2 6.8 5.5 0.0 3.2 4 0 0 4 4 4 0 PIF1-like helicase MobB PF03205.9 KNZ78831.1 - 0.29 10.8 1.2 10 5.8 0.0 3.4 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B DAGAT PF03982.8 KNZ78832.1 - 2.4e-102 341.6 0.0 2.9e-102 341.3 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Fe_dep_repr_C PF02742.10 KNZ78834.1 - 0.025 14.2 0.1 0.048 13.3 0.1 1.4 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Lipase_3 PF01764.20 KNZ78837.1 - 2.6e-17 62.7 0.1 3.6e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KNZ78837.1 - 0.00053 19.9 0.6 0.001 19.0 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ78837.1 - 0.0041 16.6 0.0 0.008 15.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ78837.1 - 0.009 15.7 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KNZ78837.1 - 0.01 15.3 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Qn_am_d_aIII PF09099.5 KNZ78837.1 - 0.011 16.0 0.2 0.019 15.2 0.1 1.4 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Acyl_transf_1 PF00698.16 KNZ78837.1 - 0.074 12.3 0.1 0.098 11.9 0.1 1.2 1 0 0 1 1 1 0 Acyl transferase domain DUF676 PF05057.9 KNZ78837.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Cellulase PF00150.13 KNZ78838.1 - 2.9e-10 39.8 0.0 7.7e-10 38.4 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NAD_binding_10 PF13460.1 KNZ78840.1 - 6.8e-08 32.7 0.2 1.1e-07 32.0 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KNZ78840.1 - 5.4e-05 23.4 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KNZ78840.1 - 0.018 14.5 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KNZ78840.1 - 0.066 12.1 0.0 8.7 5.1 0.0 2.2 1 1 0 2 2 2 0 Male sterility protein Ytp1 PF10355.4 KNZ78841.1 - 1.6e-75 253.7 11.4 1.6e-75 253.7 7.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KNZ78841.1 - 3.8e-27 93.9 0.2 3.8e-27 93.9 0.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 KNZ78841.1 - 0.0011 18.8 5.9 0.0011 18.8 4.1 3.7 4 1 0 4 4 4 1 Eukaryotic cytochrome b561 DUF4225 PF13988.1 KNZ78841.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) DUF373 PF04123.8 KNZ78841.1 - 2.8 6.8 5.6 0.41 9.6 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF373) zf-DHHC PF01529.15 KNZ78841.1 - 7.1 5.9 7.4 20 4.5 5.2 2.0 1 1 0 1 1 1 0 DHHC palmitoyltransferase Lactamase_B_2 PF12706.2 KNZ78842.1 - 1.7e-28 99.4 0.1 1.2e-27 96.7 0.1 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KNZ78842.1 - 2.7e-09 36.3 0.0 1.5e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 KNZ78842.1 - 5.7e-06 26.1 0.6 2.4e-05 24.0 0.4 2.2 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily MFS_1 PF07690.11 KNZ78843.1 - 5.1e-29 101.0 48.1 6.3e-28 97.4 16.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ78843.1 - 1.4e-08 33.7 20.2 1e-06 27.6 3.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 KNZ78843.1 - 0.00021 19.6 0.9 0.00041 18.6 0.6 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MRI PF15325.1 KNZ78844.1 - 0.081 13.9 0.8 0.21 12.5 0.6 1.7 1 0 0 1 1 1 0 Modulator of retrovirus infection MFS_1 PF07690.11 KNZ78845.1 - 1.7e-25 89.5 19.4 1.7e-25 89.5 13.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ78845.1 - 6.7e-06 24.9 22.0 3.7e-05 22.4 15.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KNZ78845.1 - 3.1e-05 22.3 0.7 6.1e-05 21.4 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PDT PF00800.13 KNZ78846.1 - 5.4e-46 156.4 0.0 7.1e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase zf-CCCH PF00642.19 KNZ78847.1 - 5.8e-15 54.5 21.6 4e-05 23.1 0.4 5.2 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 KNZ78847.1 - 0.00038 20.2 7.5 0.00067 19.4 2.9 3.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 KNZ78847.1 - 0.0021 17.7 0.4 0.0055 16.4 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH_2 PF14608.1 KNZ78847.1 - 0.072 13.1 0.3 0.072 13.1 0.2 5.5 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type UPF0047 PF01894.12 KNZ78848.1 - 1.2e-33 115.4 0.2 1.3e-33 115.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Fungal_trans PF04082.13 KNZ78849.1 - 0.0024 16.7 0.0 0.018 13.9 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ras PF00071.17 KNZ78851.1 - 7.6e-35 119.6 0.0 8.8e-35 119.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ78851.1 - 1.2e-09 38.6 0.0 1.7e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KNZ78851.1 - 0.044 13.2 0.0 0.057 12.8 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF423 PF04241.10 KNZ78853.1 - 1.2e-18 66.7 2.4 1.9e-18 66.1 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Ifi-6-16 PF06140.8 KNZ78853.1 - 0.23 11.2 0.2 0.23 11.2 0.1 2.4 2 1 0 2 2 2 0 Interferon-induced 6-16 family Spb1_C PF07780.7 KNZ78854.1 - 1.1e-65 221.1 22.6 1.1e-65 221.1 15.7 3.1 3 1 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.14 KNZ78854.1 - 5e-53 179.7 0.0 1.2e-52 178.4 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 KNZ78854.1 - 1.4e-45 154.6 3.1 1.4e-45 154.6 2.1 4.9 4 2 2 6 6 6 1 Domain of unknown function (DUF3381) UPF0181 PF03701.9 KNZ78854.1 - 0.054 12.8 0.1 0.18 11.1 0.1 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) SLS PF14611.1 KNZ78855.1 - 1.3e-05 24.7 0.0 4.7e-05 22.9 0.0 1.7 1 1 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator zf-RVT PF13966.1 KNZ78856.1 - 0.0081 16.4 2.9 0.091 13.0 0.5 2.2 1 1 1 2 2 2 1 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.2 KNZ78856.1 - 0.017 14.9 0.9 0.11 12.3 0.6 2.3 1 1 0 1 1 1 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 KNZ78856.1 - 0.096 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding 7tm_2 PF00002.19 KNZ78856.1 - 1.9 7.5 4.6 0.41 9.6 1.0 1.5 2 0 0 2 2 2 0 7 transmembrane receptor (Secretin family) Abhydrolase_6 PF12697.2 KNZ78857.1 - 2.6e-23 83.0 0.0 3.3e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ78857.1 - 4.1e-11 42.8 0.1 4.5e-10 39.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ78857.1 - 3.5e-09 36.5 0.0 7.6e-09 35.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KNZ78857.1 - 1.7e-05 25.1 0.0 2.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 KNZ78857.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S15 PF02129.13 KNZ78857.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3328 PF11807.3 KNZ78858.1 - 1.4e-15 57.5 0.0 1.5e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 KNZ78860.1 - 3.2e-26 92.3 2.8 3.8e-26 92.1 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Chromo PF00385.19 KNZ78862.1 - 9.2e-11 41.2 0.6 1.4e-10 40.6 0.4 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SF3a60_bindingd PF12108.3 KNZ78862.1 - 0.023 14.2 0.3 0.053 13.0 0.2 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain F-box PF00646.28 KNZ78863.1 - 1.2e-05 24.7 0.4 4.7e-05 22.9 0.3 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KNZ78863.1 - 0.00064 19.3 0.1 0.0022 17.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like TIM PF00121.13 KNZ78864.1 - 6.3e-87 290.6 0.0 7.1e-87 290.5 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 KNZ78864.1 - 0.00093 18.4 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 CutC family GLE1 PF07817.8 KNZ78865.1 - 2.5e-32 111.8 0.0 6.1e-32 110.5 0.0 1.7 1 0 0 1 1 1 1 GLE1-like protein Kei1 PF08552.6 KNZ78865.1 - 0.96 9.0 3.4 54 3.3 1.9 2.7 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Biotin_lipoyl PF00364.17 KNZ78866.1 - 7.1e-17 60.8 0.4 1.5e-16 59.7 0.1 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 KNZ78866.1 - 7.2e-07 28.7 0.4 2.9e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KNZ78866.1 - 0.043 13.4 0.2 0.34 10.6 0.0 2.5 3 1 1 4 4 4 0 Biotin-lipoyl like Sterol-sensing PF12349.3 KNZ78867.1 - 1.4e-35 122.0 8.2 3.4e-35 120.7 5.7 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KNZ78867.1 - 2.3e-09 35.7 6.8 3.2e-09 35.3 4.7 1.1 1 0 0 1 1 1 1 Patched family DUF1077 PF06417.7 KNZ78868.1 - 3.4e-32 110.4 1.1 4.5e-32 110.0 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Sen15 PF09631.5 KNZ78869.1 - 2.1e-18 66.4 0.0 2.6e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein Oxidored_molyb PF00174.14 KNZ78870.1 - 2e-38 131.4 0.0 6.2e-38 129.8 0.0 1.9 2 1 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KNZ78870.1 - 3.4e-24 84.9 1.5 5.8e-24 84.1 1.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain HCBP_related PF06594.6 KNZ78870.1 - 0.027 14.0 0.1 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain RRM_1 PF00076.17 KNZ78871.1 - 9e-35 118.1 0.0 1.8e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ78871.1 - 1.3e-15 57.1 0.0 7.4e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ78871.1 - 2.6e-09 36.7 0.0 0.0019 18.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KNZ78871.1 - 0.011 15.2 0.1 0.12 11.8 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain Ras PF00071.17 KNZ78872.1 - 3.8e-54 182.4 0.0 4.3e-54 182.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ78872.1 - 2.7e-16 60.1 0.0 4.2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ78872.1 - 6.8e-08 31.9 0.0 9.1e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family WD40 PF00400.27 KNZ78873.1 - 1.7e-06 27.6 6.5 9.1e-05 22.1 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat CMD PF02627.15 KNZ78874.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family CMD PF02627.15 KNZ78875.1 - 0.074 12.9 0.0 0.36 10.7 0.0 2.1 2 1 1 3 3 3 0 Carboxymuconolactone decarboxylase family Ribonuclease_3 PF00636.21 KNZ78876.1 - 3.2e-40 137.1 0.0 9.2e-21 74.4 0.0 2.8 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KNZ78876.1 - 7.7e-27 93.7 0.1 7.2e-14 51.8 0.0 3.8 2 2 0 2 2 2 2 Ribonuclease-III-like DEAD PF00270.24 KNZ78876.1 - 5.2e-15 55.3 0.0 8.6e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ78876.1 - 1.1e-13 50.8 0.0 2.5e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ78876.1 - 2.4e-13 50.3 0.0 4.9e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.9 KNZ78876.1 - 6.3e-11 41.9 0.0 1.3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain SNF2_N PF00176.18 KNZ78876.1 - 2.8e-05 23.0 0.1 5.2e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.4 KNZ78876.1 - 0.042 12.8 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CDC45 PF02724.9 KNZ78877.1 - 0.054 11.5 1.1 0.1 10.6 0.7 1.4 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 KNZ78877.1 - 1.1 7.5 11.2 0.024 13.0 3.3 1.5 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Terpene_synth_C PF03936.11 KNZ78880.1 - 1.5e-13 50.5 0.0 2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DNA_pol_A_exo1 PF01612.15 KNZ78882.1 - 1.2e-09 37.9 0.3 0.00077 18.9 0.0 3.1 2 1 1 3 3 3 2 3'-5' exonuclease ProRS-C_1 PF09180.6 KNZ78882.1 - 0.067 13.1 0.9 1.1 9.2 0.4 2.8 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal p450 PF00067.17 KNZ78883.1 - 2.6e-58 197.6 0.0 1.8e-57 194.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Ras PF00071.17 KNZ78884.1 - 4.6e-54 182.1 0.0 5.6e-54 181.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ78884.1 - 1.7e-15 57.5 0.0 3.1e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ78884.1 - 1.9e-06 27.2 0.0 3.8e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KNZ78884.1 - 0.0041 16.3 0.0 0.006 15.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KNZ78884.1 - 0.08 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Amino_oxidase PF01593.19 KNZ78885.1 - 7.5e-75 252.7 0.0 1.8e-72 244.8 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KNZ78885.1 - 1.2e-11 44.4 0.2 3.3e-11 43.0 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KNZ78885.1 - 2.3e-05 23.4 0.4 0.00016 20.7 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KNZ78885.1 - 3.2e-05 23.1 0.5 0.00016 20.8 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KNZ78885.1 - 0.00094 18.3 3.7 0.0078 15.3 2.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ78885.1 - 0.0011 17.9 1.0 0.0019 17.1 0.4 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KNZ78885.1 - 0.0028 17.7 1.0 0.0079 16.2 0.5 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KNZ78885.1 - 0.013 15.8 0.8 0.038 14.3 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KNZ78885.1 - 0.02 14.4 0.1 0.048 13.2 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 KNZ78885.1 - 0.025 14.6 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KNZ78885.1 - 0.031 13.1 1.6 0.27 10.0 0.2 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KNZ78885.1 - 0.044 12.2 0.1 0.073 11.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 KNZ78885.1 - 0.13 12.1 0.2 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2461 PF09365.5 KNZ78886.1 - 1.7e-60 204.0 0.0 5.2e-32 110.9 0.1 2.3 2 0 0 2 2 2 2 Conserved hypothetical protein (DUF2461) DNA_pol_A_exo1 PF01612.15 KNZ78887.1 - 2.7e-10 40.0 0.0 7.9e-10 38.4 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Fungal_trans PF04082.13 KNZ78888.1 - 1.4e-19 69.9 0.1 2.8e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ78888.1 - 0.0021 17.9 4.7 0.0044 16.9 3.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 KNZ78889.1 - 0.00034 20.2 0.0 0.00098 18.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ78889.1 - 0.0024 17.4 0.0 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 F-box domain TPMT PF05724.6 KNZ78890.1 - 2.3e-27 95.8 0.0 5.3e-16 58.7 0.0 2.1 1 1 1 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 KNZ78890.1 - 2.7e-12 46.5 0.0 3.8e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ78890.1 - 1.2e-08 35.5 0.0 1.8e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ78890.1 - 3e-08 33.9 0.0 3.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ78890.1 - 2.4e-07 31.1 0.0 8.1e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ78890.1 - 3.2e-07 30.3 0.0 8.1e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ78890.1 - 2.3e-05 24.7 0.0 9.6e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ78890.1 - 3.1e-05 23.7 0.0 6.8e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KNZ78890.1 - 0.0061 16.2 0.0 0.0082 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ78890.1 - 0.021 14.2 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.9 KNZ78890.1 - 0.023 13.8 0.0 0.041 13.0 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB HMG_box PF00505.14 KNZ78892.1 - 2.3e-11 43.7 0.4 2.3e-11 43.7 0.3 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KNZ78892.1 - 3.3e-05 24.1 0.1 0.0001 22.5 0.1 1.8 1 0 0 1 1 1 1 HMG-box domain AvrE PF11725.3 KNZ78893.1 - 2.6 4.9 6.5 3.1 4.7 4.5 1.0 1 0 0 1 1 1 0 Pathogenicity factor CytochromB561_N PF09786.4 KNZ78893.1 - 3 6.1 11.7 4.2 5.7 8.1 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Apo-CIII PF05778.7 KNZ78894.1 - 0.11 11.8 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) HsbA PF12296.3 KNZ78895.1 - 5.7e-15 55.2 5.8 8.2e-15 54.7 4.0 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.7 KNZ78895.1 - 0.053 13.3 5.1 0.13 12.0 3.5 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF3a60_bindingd PF12108.3 KNZ78895.1 - 0.11 12.0 0.2 0.11 12.0 0.1 1.6 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Phage_holin_2 PF04550.7 KNZ78896.1 - 0.0077 16.3 5.3 0.019 15.0 0.0 2.6 2 1 0 2 2 2 1 Phage holin family 2 HMG_box PF00505.14 KNZ78898.1 - 1e-13 51.3 0.6 1.9e-13 50.4 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KNZ78898.1 - 0.005 17.1 0.1 0.005 17.1 0.1 1.8 2 0 0 2 2 2 1 HMG-box domain BTB PF00651.26 KNZ78899.1 - 5.7e-08 32.7 0.0 1.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.11 KNZ78900.1 - 2.4e-32 112.0 57.6 6.6e-32 110.5 34.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Fzo_mitofusin PF04799.8 KNZ78900.1 - 0.071 12.4 0.2 0.14 11.5 0.2 1.4 1 0 0 1 1 1 0 fzo-like conserved region Phage_holin_2 PF04550.7 KNZ78903.1 - 6.2 6.9 10.5 24 5.1 4.5 2.5 1 1 2 3 3 3 0 Phage holin family 2 Pkinase PF00069.20 KNZ78904.1 - 2.1e-45 154.8 0.0 8.5e-45 152.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ78904.1 - 8.6e-15 54.4 0.0 4.1e-08 32.5 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KNZ78904.1 - 6.7e-08 31.8 0.0 0.0003 19.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KNZ78904.1 - 0.0026 17.5 0.0 0.035 13.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family MraZ PF02381.13 KNZ78904.1 - 0.13 12.0 0.1 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 MraZ protein Attractin PF08037.6 KNZ78904.1 - 5.4 6.8 11.5 19 5.1 7.9 1.9 1 1 0 1 1 1 0 Attractin family Peptidase_S8 PF00082.17 KNZ78905.1 - 3.1e-26 92.1 1.4 5.5e-26 91.3 1.0 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KNZ78905.1 - 0.043 14.3 0.0 0.2 12.2 0.0 2.0 1 1 0 1 1 1 0 Peptidase inhibitor I9 HpcH_HpaI PF03328.9 KNZ78907.1 - 1.4e-32 112.4 0.0 1.8e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 KNZ78907.1 - 0.0034 16.0 0.0 0.0054 15.3 0.0 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain DUF455 PF04305.9 KNZ78909.1 - 6.1e-88 294.3 0.0 7.3e-88 294.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 KNZ78909.1 - 4.8e-06 26.0 0.1 9.9e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Arabinose_Iso_C PF11762.3 KNZ78909.1 - 0.051 13.1 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain RNase_H PF00075.19 KNZ78910.1 - 0.021 15.1 0.0 0.031 14.6 0.0 1.3 1 0 0 1 1 1 0 RNase H GIDA PF01134.17 KNZ78912.1 - 1.9e-117 392.4 0.0 2.3e-117 392.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KNZ78912.1 - 3.8e-15 55.7 0.0 1.2e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 GidA associated domain 3 ATG22 PF11700.3 KNZ78914.1 - 2.1e-137 458.4 23.9 3.1e-137 457.9 14.3 1.9 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KNZ78914.1 - 1.2e-07 30.7 46.8 0.00023 20.0 4.1 3.2 1 1 1 3 3 3 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 KNZ78915.1 - 8.6e-22 78.1 0.0 1.1e-21 77.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ78915.1 - 1.2e-10 41.3 0.0 1.8e-10 40.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ78915.1 - 3.4e-09 36.5 0.0 4e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KNZ78915.1 - 1.8e-06 27.6 0.0 1.3e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase FSH1 PF03959.8 KNZ78915.1 - 0.083 12.3 0.0 0.26 10.6 0.0 1.8 2 1 0 2 2 2 0 Serine hydrolase (FSH1) WD40 PF00400.27 KNZ78917.1 - 4.7e-54 178.4 17.7 3.9e-09 36.0 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KNZ78917.1 - 0.0015 17.3 0.1 0.13 10.9 0.0 2.6 1 1 1 2 2 2 2 Nup133 N terminal like BBS2_Mid PF14783.1 KNZ78917.1 - 0.0062 16.3 0.3 6.2 6.6 0.0 3.8 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 KNZ78917.1 - 0.013 13.6 1.8 1.9 6.5 0.5 3.7 1 1 2 3 3 3 0 Nucleoporin Nup120/160 TFIIS_M PF07500.9 KNZ78918.1 - 4.6e-34 116.9 2.2 5.5e-33 113.4 0.2 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.6 KNZ78918.1 - 2.1e-13 49.5 0.7 4.1e-13 48.5 0.5 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TFIIS_C PF01096.13 KNZ78918.1 - 3.3e-11 42.6 5.9 5.4e-11 41.9 4.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Rop-like PF05082.8 KNZ78918.1 - 0.093 12.2 1.1 8.6 5.9 0.1 2.6 2 0 0 2 2 2 0 Rop-like DUF3713 PF12506.3 KNZ78918.1 - 1.7 8.7 6.8 0.54 10.3 1.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3713) FtsH_ext PF06480.10 KNZ78920.1 - 2.9 8.1 7.5 1.7 8.8 0.3 3.3 3 0 0 3 3 3 0 FtsH Extracellular DRY_EERY PF09750.4 KNZ78923.1 - 0.01 15.9 1.2 0.035 14.1 0.8 1.9 1 1 0 1 1 1 0 Alternative splicing regulator Peptidase_M48 PF01435.13 KNZ78924.1 - 3.8e-46 157.4 0.1 5.6e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 KNZ78924.1 - 0.0064 15.5 0.5 0.012 14.5 0.3 1.4 1 0 0 1 1 1 1 BlaR1 peptidase M56 SprT-like PF10263.4 KNZ78924.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 SprT-like family DUF4131 PF13567.1 KNZ78924.1 - 8.7 5.7 9.1 4.5 6.6 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Rad60-SLD PF11976.3 KNZ78925.1 - 6.2e-09 35.4 0.0 1.3e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KNZ78925.1 - 0.0041 16.4 0.0 0.012 15.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family PhyH PF05721.8 KNZ78928.1 - 4.6e-11 43.1 0.0 6.7e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) LRR_4 PF12799.2 KNZ78929.1 - 0.025 14.2 6.7 2.3 7.9 0.2 4.4 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) Sulfate_transp PF00916.15 KNZ78930.1 - 1.3e-42 145.7 1.2 1.3e-42 145.7 0.9 1.9 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 KNZ78930.1 - 9.8e-15 54.1 0.0 2.2e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KNZ78930.1 - 7.3e-10 38.2 0.0 1.5e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain NUDIX_2 PF13869.1 KNZ78931.1 - 1.1e-82 275.9 0.0 1.3e-82 275.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase RhoGEF PF00621.15 KNZ78932.1 - 1.2e-21 77.4 0.0 1.9e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Serglycin PF04360.7 KNZ78932.1 - 0.0038 16.9 0.0 0.0038 16.9 0.0 3.9 3 1 0 3 3 3 2 Serglycin Abhydrolase_3 PF07859.8 KNZ78933.1 - 1.4e-16 60.6 0.1 3.1e-16 59.6 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KNZ78933.1 - 7.6e-10 38.1 0.7 5.8e-09 35.2 0.5 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KNZ78933.1 - 2.9e-08 33.5 0.0 4.9e-08 32.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KNZ78933.1 - 4.1e-06 25.8 0.0 7.1e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 KNZ78933.1 - 6.9e-06 25.1 0.0 1.4e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 KNZ78933.1 - 1.4e-05 25.0 0.5 1.9e-05 24.6 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ78933.1 - 0.00024 20.3 0.0 0.022 14.0 0.0 2.5 2 1 0 2 2 2 1 Prolyl oligopeptidase family DUF1057 PF06342.7 KNZ78933.1 - 0.081 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DIOX_N PF14226.1 KNZ78934.1 - 1.2e-23 83.8 0.0 2.1e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KNZ78934.1 - 6e-19 68.1 0.0 9.1e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidase02_C PF12123.3 KNZ78934.1 - 0.02 14.5 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF2292 PF10055.4 KNZ78934.1 - 0.064 12.5 0.4 0.15 11.4 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2292) DUF4243 PF14027.1 KNZ78935.1 - 1.7e-86 290.7 0.0 2.3e-86 290.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) EPL1 PF10513.4 KNZ78936.1 - 2.9e-18 66.6 1.5 6.3e-18 65.5 0.1 2.3 2 0 0 2 2 2 1 Enhancer of polycomb-like Xan_ur_permease PF00860.15 KNZ78937.1 - 3.9e-30 104.6 30.4 1.1e-19 70.2 7.7 2.6 1 1 1 2 2 2 2 Permease family F-box-like PF12937.2 KNZ78938.1 - 8.2e-08 31.8 0.1 2.2e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ78938.1 - 0.0032 17.0 0.2 0.011 15.4 0.1 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 KNZ78938.1 - 0.03 13.9 0.6 40 3.9 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF4243 PF14027.1 KNZ78939.1 - 1.9e-86 290.5 0.5 2.2e-86 290.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Cyt-b5 PF00173.23 KNZ78940.1 - 6.7e-10 38.6 0.0 9.1e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fungal_trans PF04082.13 KNZ78941.1 - 5.5e-15 54.9 0.2 9.6e-15 54.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sld5 PF05916.6 KNZ78942.1 - 9.5e-06 25.8 1.8 5.3e-05 23.4 0.7 2.2 1 1 1 2 2 2 1 GINS complex protein Herpes_UL14 PF03580.9 KNZ78942.1 - 0.0057 16.4 2.6 0.011 15.5 1.8 1.4 1 0 0 1 1 1 1 Herpesvirus UL14-like protein Helicase_Sgs1 PF11408.3 KNZ78942.1 - 0.066 13.0 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Sgs1 RecQ helicase CBFD_NFYB_HMF PF00808.18 KNZ78943.1 - 1.1e-12 47.7 2.1 7.5e-12 45.1 1.4 2.1 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KNZ78943.1 - 0.00042 20.3 0.2 0.0011 18.9 0.2 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 KNZ78943.1 - 0.064 13.0 1.0 0.1 12.3 0.7 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region CPSase_L_D2 PF02786.12 KNZ78945.1 - 2.2e-116 386.5 0.1 2.4e-83 278.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 KNZ78945.1 - 1.9e-45 154.6 0.0 7.1e-45 152.8 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 KNZ78945.1 - 6.4e-45 152.3 0.0 1.4e-44 151.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 KNZ78945.1 - 1.3e-41 141.1 0.1 3.3e-41 139.9 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 KNZ78945.1 - 1.4e-40 137.8 0.0 2e-19 69.7 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KNZ78945.1 - 6.8e-40 136.7 0.1 2.4e-23 82.8 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 KNZ78945.1 - 5.3e-34 117.3 0.1 2.1e-33 115.4 0.0 2.1 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain CPSase_sm_chain PF00988.17 KNZ78945.1 - 2.4e-28 98.2 0.0 6.6e-28 96.8 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain ATPgrasp_Ter PF15632.1 KNZ78945.1 - 9.9e-23 80.3 0.2 2.4e-09 36.4 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 KNZ78945.1 - 3.5e-18 65.3 0.0 2e-17 62.8 0.0 2.5 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 KNZ78945.1 - 2.2e-17 63.1 0.1 1.8e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KNZ78945.1 - 3.6e-17 62.2 0.0 4.9e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 KNZ78945.1 - 3.5e-06 26.6 0.0 0.0013 18.2 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KNZ78945.1 - 3.5e-06 26.9 0.1 0.024 14.5 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Peptidase_C26 PF07722.8 KNZ78945.1 - 3.6e-05 23.3 0.0 0.00073 19.0 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 KNZ78945.1 - 0.00024 20.6 0.0 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 1 DJ-1/PfpI family ATP-grasp_5 PF13549.1 KNZ78945.1 - 0.0097 15.1 0.0 3.1 6.9 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain DUF3806 PF12713.2 KNZ78945.1 - 0.065 12.6 0.1 0.95 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3806) Tubulin PF00091.20 KNZ78946.1 - 7e-70 235.2 0.0 1.2e-69 234.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KNZ78946.1 - 4.2e-49 165.7 0.1 6.7e-49 165.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KNZ78946.1 - 2.2e-06 27.7 0.0 6.4e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KNZ78946.1 - 0.037 13.4 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Hydrophobin PF01185.13 KNZ78947.1 - 1.6e-17 63.6 5.6 2e-17 63.4 3.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin WAP PF00095.16 KNZ78947.1 - 1 9.3 7.7 5.4 7.0 0.7 2.3 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' DUF3433 PF11915.3 KNZ78948.1 - 9.6e-13 48.1 1.2 2.6e-12 46.7 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) SSrecog PF03531.9 KNZ78948.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Structure-specific recognition protein (SSRP1) Zip PF02535.17 KNZ78949.1 - 6.6e-49 166.6 1.7 1e-48 166.0 1.2 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter DUF165 PF02592.10 KNZ78949.1 - 0.14 12.3 1.9 0.16 12.1 0.0 2.0 2 1 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 F_bP_aldolase PF01116.15 KNZ78950.1 - 1.9e-63 214.2 0.0 2.5e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Epimerase PF01370.16 KNZ78950.1 - 6.8e-19 68.2 0.0 2.2e-18 66.5 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KNZ78950.1 - 1.9e-05 24.6 0.0 7.4e-05 22.7 0.0 2.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KNZ78950.1 - 0.0001 21.3 0.0 0.0018 17.2 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 KNZ78950.1 - 0.0024 16.6 0.0 0.004 15.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KNZ78950.1 - 0.0037 16.2 0.0 0.012 14.5 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 KNZ78950.1 - 0.13 11.8 1.0 0.73 9.4 0.2 2.5 2 1 0 2 2 2 0 KR domain Peptidase_A22B PF04258.8 KNZ78950.1 - 0.2 11.0 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Signal peptide peptidase Fungal_trans PF04082.13 KNZ78951.1 - 8.7e-12 44.4 0.0 2.3e-11 43.0 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain EamA PF00892.15 KNZ78952.1 - 4.3e-26 91.4 28.2 3.3e-16 59.4 5.7 3.0 2 1 1 3 3 3 3 EamA-like transporter family EmrE PF13536.1 KNZ78952.1 - 1.4e-09 38.1 28.9 2.1e-07 31.1 5.5 3.2 2 1 1 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 KNZ78952.1 - 0.0082 15.7 2.6 0.0082 15.7 1.8 2.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family DUF1469 PF07332.6 KNZ78952.1 - 4.4 7.0 21.0 3.8 7.2 0.3 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1469) DUF4244 PF14029.1 KNZ78954.1 - 0.064 12.3 0.2 0.064 12.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) PIF1 PF05970.9 KNZ78955.1 - 1.4e-34 119.6 0.5 1.6e-34 119.4 0.3 1.1 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 KNZ78955.1 - 0.0056 16.7 0.0 0.015 15.4 0.0 1.8 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Exo70 PF03081.10 KNZ78955.1 - 0.11 11.2 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit PIF1 PF05970.9 KNZ78956.1 - 5e-31 107.9 0.0 6.2e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 KNZ78956.1 - 0.022 14.5 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KNZ78956.1 - 0.023 14.2 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KNZ78956.1 - 0.028 13.8 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KNZ78956.1 - 0.039 13.9 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 KNZ78956.1 - 0.09 12.9 0.1 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 KNZ78956.1 - 0.095 12.8 0.8 2.4 8.3 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) DSX_dimer PF08828.5 KNZ78956.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Doublesex dimerisation domain Helitron_like_N PF14214.1 KNZ78957.1 - 1.6e-20 73.6 0.0 2.1e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ78957.1 - 0.12 11.8 0.2 0.16 11.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) zf-C2H2_4 PF13894.1 KNZ78960.1 - 0.11 12.8 0.3 0.24 11.7 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-HYPF PF07503.7 KNZ78960.1 - 2.1 7.8 6.3 0.14 11.5 0.6 1.8 2 0 0 2 2 2 0 HypF finger Pkinase_Tyr PF07714.12 KNZ78962.1 - 8e-38 129.9 0.0 1.4e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ78962.1 - 2.6e-37 128.3 0.0 4.4e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Patatin PF01734.17 KNZ78962.1 - 2.5e-14 53.6 0.1 6.8e-14 52.2 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase Kinase-like PF14531.1 KNZ78962.1 - 0.0003 19.8 0.0 0.00046 19.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Patatin PF01734.17 KNZ78963.1 - 4.9e-24 85.4 0.0 1.2e-23 84.1 0.0 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase UBN2_2 PF14227.1 KNZ78964.1 - 1.5e-06 27.7 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ78964.1 - 4.1e-05 23.3 0.0 7.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KNZ78964.1 - 0.00086 19.1 1.1 0.0015 18.3 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 KNZ78964.1 - 0.08 12.8 2.7 0.12 12.3 1.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Chromo PF00385.19 KNZ78966.1 - 8.5e-15 54.1 0.2 1e-14 53.9 0.2 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain OCD_Mu_crystall PF02423.10 KNZ78967.1 - 7.2e-24 84.1 1.0 1.1e-23 83.4 0.7 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 KNZ78967.1 - 0.0052 16.8 0.0 0.015 15.4 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Cys_Met_Meta_PP PF01053.15 KNZ78970.1 - 3.4e-138 460.1 0.0 3.9e-138 459.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KNZ78970.1 - 1.2e-08 34.3 0.2 3.6e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KNZ78970.1 - 3.7e-06 25.9 0.2 6.4e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KNZ78970.1 - 0.0009 18.4 0.0 0.0024 17.0 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 KNZ78970.1 - 0.0011 17.7 0.0 0.0016 17.2 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 KNZ78970.1 - 0.024 12.9 0.0 0.035 12.4 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase ABC_sub_bind PF04392.7 KNZ78970.1 - 0.095 11.6 0.1 0.24 10.3 0.0 1.6 2 0 0 2 2 2 0 ABC transporter substrate binding protein TPR_12 PF13424.1 KNZ78971.1 - 3.5e-14 52.4 8.9 2.9e-05 23.9 0.1 5.7 2 2 3 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ78971.1 - 3.3e-09 35.9 6.3 0.34 10.9 0.1 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat AAA_22 PF13401.1 KNZ78971.1 - 4.6e-09 36.5 0.4 5.2e-08 33.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 KNZ78971.1 - 7.7e-08 31.5 0.0 1.5e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 KNZ78971.1 - 2.6e-06 26.9 3.2 0.026 14.1 0.1 4.8 3 1 3 6 6 6 2 TPR repeat TPR_16 PF13432.1 KNZ78971.1 - 2.2e-05 24.9 6.8 0.036 14.7 0.3 4.4 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ78971.1 - 8e-05 22.1 2.8 5.9 6.9 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ78971.1 - 8.6e-05 22.8 3.9 2.3 9.1 0.2 5.8 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ78971.1 - 0.00011 22.4 5.9 0.078 13.3 0.4 4.4 3 1 0 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.1 KNZ78971.1 - 0.00015 21.7 1.0 0.0014 18.6 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain TPR_6 PF13174.1 KNZ78971.1 - 0.001 19.3 5.0 42 4.9 0.1 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ78971.1 - 0.0012 18.3 5.0 1.3 8.7 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA PF00004.24 KNZ78971.1 - 0.0028 17.8 0.0 0.0087 16.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TPR_7 PF13176.1 KNZ78971.1 - 0.0041 16.8 2.4 2.1 8.3 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF258 PF03193.11 KNZ78971.1 - 0.015 14.4 0.0 0.051 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 KNZ78971.1 - 0.02 14.5 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TPR_10 PF13374.1 KNZ78971.1 - 0.041 13.8 9.7 3.5 7.6 0.3 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat Guanylate_kin PF00625.16 KNZ78971.1 - 0.063 12.7 0.0 12 5.2 0.0 2.5 2 0 0 2 2 2 0 Guanylate kinase AAA_7 PF12775.2 KNZ78971.1 - 0.065 12.2 0.0 0.51 9.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 DUF1911 PF08929.5 KNZ78972.1 - 6.8 7.4 8.1 14 6.4 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) OTT_1508_deam PF14441.1 KNZ78973.1 - 1.5e-07 31.3 0.1 3.9e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF4443 PF14544.1 KNZ78973.1 - 0.006 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4443) OTT_1508_deam PF14441.1 KNZ78974.1 - 4.4e-05 23.3 0.0 7.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase Peptidase_M36 PF02128.10 KNZ78975.1 - 2e-127 425.1 10.6 4.5e-127 423.9 7.3 1.6 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 KNZ78975.1 - 1.5e-10 40.3 1.5 3.1e-10 39.3 1.0 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 KNZ78975.1 - 0.0028 17.4 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Herpes_Helicase PF02689.9 KNZ78976.1 - 5.4e-07 27.7 0.0 5.7e-07 27.6 0.0 1.0 1 0 0 1 1 1 1 Helicase Pyr_redox_2 PF07992.9 KNZ78977.1 - 2e-29 102.9 0.5 1.9e-28 99.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KNZ78977.1 - 4.9e-19 68.5 2.4 1.9e-13 50.5 0.0 4.0 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 KNZ78977.1 - 3.8e-17 62.7 0.4 2e-14 53.8 0.1 2.8 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ78977.1 - 2.4e-12 47.1 0.0 5.5e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Pyr_redox_3 PF13738.1 KNZ78977.1 - 2.9e-08 34.0 0.2 0.0076 16.3 0.0 3.4 2 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.5 KNZ78977.1 - 5.3e-07 29.4 0.1 1.7e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 KR domain Thi4 PF01946.12 KNZ78977.1 - 4.6e-06 25.8 1.3 0.00011 21.4 0.0 2.9 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 KNZ78977.1 - 0.00022 20.2 2.5 0.053 12.4 0.1 3.3 2 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KNZ78977.1 - 0.00034 19.2 2.0 0.21 10.0 0.1 3.1 4 0 0 4 4 4 2 HI0933-like protein Shikimate_DH PF01488.15 KNZ78977.1 - 0.00063 19.8 0.8 2.2 8.3 0.0 3.4 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KNZ78977.1 - 0.00074 18.4 0.5 0.0088 14.9 0.1 2.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KNZ78977.1 - 0.0013 18.6 1.3 0.011 15.7 0.0 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DUF1776 PF08643.5 KNZ78977.1 - 0.0028 16.8 0.0 0.26 10.4 0.0 2.2 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_7 PF13241.1 KNZ78977.1 - 0.0035 17.5 0.1 0.18 12.0 0.0 3.1 3 1 0 3 3 3 1 Putative NAD(P)-binding ApbA PF02558.11 KNZ78977.1 - 0.0039 16.6 1.8 1.9 7.9 0.0 3.4 4 0 0 4 4 3 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 KNZ78977.1 - 0.0067 15.5 4.4 0.1 11.6 0.0 3.2 3 1 1 4 4 4 1 FAD binding domain FAD_oxidored PF12831.2 KNZ78977.1 - 0.017 14.2 0.0 0.26 10.2 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KNZ78977.1 - 0.02 13.8 0.1 0.02 13.8 0.1 3.7 5 1 1 6 6 6 0 Glucose inhibited division protein A K_oxygenase PF13434.1 KNZ78977.1 - 0.029 13.3 0.0 1.8 7.4 0.0 3.2 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_10 PF13460.1 KNZ78977.1 - 0.03 14.3 0.3 1.6 8.7 0.0 2.9 3 0 0 3 3 3 0 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 KNZ78977.1 - 0.032 13.9 0.6 2.9 7.5 0.1 3.0 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 KNZ78977.1 - 0.033 12.8 0.3 0.11 11.0 0.1 2.0 3 0 0 3 3 3 0 Tryptophan halogenase F420_oxidored PF03807.12 KNZ78977.1 - 0.033 14.6 0.3 14 6.2 0.0 3.5 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KNZ78977.1 - 0.43 10.2 2.4 23 4.5 0.1 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2OG-FeII_Oxy PF03171.15 KNZ78978.1 - 1.2e-23 83.2 0.0 2.5e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KNZ78978.1 - 5.4e-19 68.8 0.0 1.7e-18 67.2 0.0 1.9 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ELFV_dehydrog PF00208.16 KNZ78979.1 - 1.7e-50 171.8 0.0 2.7e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KNZ78979.1 - 6.1e-21 73.6 0.0 3.5e-15 54.6 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 KNZ78979.1 - 0.0056 16.2 0.0 0.014 15.0 0.0 1.7 1 1 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain PTCB-BRCT PF12738.2 KNZ78980.1 - 3.5e-32 110.0 0.0 1.6e-14 53.4 0.0 3.8 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 KNZ78980.1 - 2.2e-24 85.3 0.0 2.3e-06 27.6 0.0 4.4 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain RNA_pol_A_bac PF01000.21 KNZ78981.1 - 5.1e-25 87.8 0.0 8e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KNZ78981.1 - 1.2e-16 59.5 0.0 2e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain O-FucT PF10250.4 KNZ78983.1 - 1e-08 34.7 0.0 2.6e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase Cep57_MT_bd PF06657.8 KNZ78985.1 - 2.4e-22 78.6 0.0 2.4e-22 78.6 0.0 3.2 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 KNZ78985.1 - 1e-09 38.1 4.8 1e-09 38.1 3.3 3.2 3 0 0 3 3 3 1 Centrosome localisation domain of PPC89 DUF663 PF04950.7 KNZ78986.1 - 1.1e-90 303.6 4.1 1.1e-89 300.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KNZ78986.1 - 1.4e-27 95.0 0.0 3.5e-27 93.7 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KNZ78986.1 - 9.9e-07 28.3 0.0 0.00067 19.1 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 KNZ78986.1 - 1.1e-05 26.2 0.0 1.1e-05 26.2 0.0 3.7 3 1 0 3 3 1 1 AAA domain AAA_22 PF13401.1 KNZ78986.1 - 2.1e-05 24.6 0.0 5.8e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ78986.1 - 3.9e-05 23.7 0.0 0.00013 22.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 KNZ78986.1 - 0.00016 21.9 2.6 0.00092 19.5 0.0 3.0 2 0 0 2 2 2 1 ABC transporter Rtf2 PF04641.7 KNZ78986.1 - 0.00029 20.1 2.7 0.00029 20.1 1.8 2.9 3 0 0 3 3 2 1 Rtf2 RING-finger MobB PF03205.9 KNZ78986.1 - 0.00041 20.0 0.1 0.0012 18.6 0.1 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KNZ78986.1 - 0.00049 19.8 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 KNZ78986.1 - 0.0011 19.2 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KNZ78986.1 - 0.0016 18.3 0.2 0.0063 16.4 0.1 2.1 2 1 0 2 2 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 KNZ78986.1 - 0.0018 18.6 0.0 0.0018 18.6 0.0 4.4 4 1 0 4 4 3 1 AAA domain AAA_24 PF13479.1 KNZ78986.1 - 0.0019 17.8 0.1 0.0052 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNZ78986.1 - 0.0029 17.3 0.1 0.0067 16.1 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain Miro PF08477.8 KNZ78986.1 - 0.0029 18.0 0.0 0.0088 16.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_25 PF13481.1 KNZ78986.1 - 0.0031 16.9 0.0 0.0081 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KNZ78986.1 - 0.0039 17.0 0.6 0.0094 15.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 KNZ78986.1 - 0.0041 17.2 0.1 0.019 15.1 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 KNZ78986.1 - 0.0049 16.7 1.9 0.016 15.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain PduV-EutP PF10662.4 KNZ78986.1 - 0.0052 16.2 0.0 0.018 14.5 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KNZ78986.1 - 0.0056 16.1 0.0 0.015 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain NB-ARC PF00931.17 KNZ78986.1 - 0.0064 15.3 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NTPase_1 PF03266.10 KNZ78986.1 - 0.01 15.5 0.2 0.023 14.4 0.1 1.6 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.1 KNZ78986.1 - 0.013 15.5 0.1 0.032 14.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KNZ78986.1 - 0.014 14.8 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KNZ78986.1 - 0.03 13.5 0.0 0.069 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 KNZ78986.1 - 0.057 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 KNZ78986.1 - 0.96 9.7 0.0 0.96 9.7 0.0 3.9 3 1 1 4 4 2 0 AAA domain AAA_11 PF13086.1 KNZ78986.1 - 1.4 8.4 6.9 2.3 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Syntaxin_2 PF14523.1 KNZ78987.1 - 3.6e-21 75.1 2.4 3.6e-21 75.1 1.6 2.2 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KNZ78987.1 - 4.9e-17 61.3 2.3 7.2e-17 60.8 0.5 2.1 2 0 0 2 2 2 1 SNARE domain MCPsignal PF00015.16 KNZ78987.1 - 0.079 12.4 1.9 0.32 10.5 0.1 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Mit_KHE1 PF10173.4 KNZ78988.1 - 3.1e-51 173.8 0.0 4.2e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related BCD PF15461.1 KNZ78988.1 - 0.035 13.5 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase F-box-like PF12937.2 KNZ78989.1 - 2.2e-07 30.4 0.3 6.9e-07 28.8 0.2 1.9 1 0 0 1 1 1 1 F-box-like MIF4G PF02854.14 KNZ78990.1 - 0.076 12.4 0.0 0.1 11.9 0.0 1.4 1 1 0 1 1 1 0 MIF4G domain Glyco_hydro_20 PF00728.17 KNZ78992.1 - 6.2e-76 255.8 0.0 9e-76 255.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Peptidase_M16 PF00675.15 KNZ78992.1 - 1.6e-53 180.4 0.2 1.6e-52 177.2 0.1 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KNZ78992.1 - 6.1e-43 146.6 0.0 9.3e-41 139.5 0.0 3.1 3 0 0 3 3 3 1 Peptidase M16 inactive domain Glycohydro_20b2 PF14845.1 KNZ78992.1 - 0.0013 19.4 0.0 0.0037 17.8 0.0 1.8 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like WD40 PF00400.27 KNZ78993.1 - 2.3e-23 81.1 23.9 2e-05 24.2 0.3 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 KNZ78993.1 - 3.9e-13 49.1 0.0 7e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Adap_comp_sub PF00928.16 KNZ78994.1 - 2.3e-90 302.2 0.0 3.6e-90 301.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KNZ78994.1 - 2.6e-06 27.2 0.3 4.7e-06 26.3 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.9 KNZ78994.1 - 0.014 13.9 0.0 0.021 13.4 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 SH3_5 PF08460.5 KNZ78994.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Scm3 PF10384.4 KNZ78995.1 - 1.1e-11 43.9 0.0 2.5e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Centromere protein Scm3 SMC_N PF02463.14 KNZ78996.1 - 1.2e-19 70.4 0.0 2.7e-19 69.3 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KNZ78996.1 - 7.8e-13 49.2 11.7 7.8e-13 49.2 8.1 5.7 3 2 2 5 5 5 1 AAA domain Reo_sigmaC PF04582.7 KNZ78996.1 - 0.026 13.7 14.8 0.47 9.5 0.2 4.7 3 2 2 5 5 5 0 Reovirus sigma C capsid protein AAA_29 PF13555.1 KNZ78996.1 - 0.03 13.8 0.0 0.087 12.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain WEMBL PF05701.6 KNZ78996.1 - 1.2 7.5 77.4 0.0033 15.9 22.5 3.5 2 1 1 3 3 3 0 Weak chloroplast movement under blue light Cytochrom_B_N_2 PF13631.1 KNZ78997.1 - 0.0053 16.5 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB MscS_TM PF12794.2 KNZ78997.1 - 0.11 11.0 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 MRVI1 PF05781.7 KNZ78997.1 - 0.12 10.7 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 MRVI1 protein HSP70 PF00012.15 KNZ78998.1 - 4.8e-61 206.4 2.0 3.2e-60 203.6 0.2 2.4 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 KNZ78998.1 - 2.5e-11 42.7 0.1 5.8e-11 41.5 0.1 1.5 1 1 0 1 1 1 1 MreB/Mbl protein DDE_3 PF13358.1 KNZ79000.1 - 5.5e-06 26.2 0.7 2.6e-05 23.9 0.4 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease ETF PF01012.16 KNZ79003.1 - 4.4e-34 117.5 0.1 6.1e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PRP1_N PF06424.7 KNZ79005.1 - 0.076 13.3 0.1 0.095 13.0 0.1 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Nipped-B_C PF12830.2 KNZ79006.1 - 4.1e-51 173.2 2.1 9.5e-51 172.1 0.5 2.4 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KNZ79006.1 - 6.4e-11 41.9 1.4 6.4e-11 41.9 1.0 3.5 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KNZ79006.1 - 0.0022 17.9 2.1 2.3 8.5 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 KNZ79006.1 - 0.005 17.0 7.3 0.05 13.8 0.8 4.5 3 1 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 KNZ79006.1 - 0.035 13.9 1.0 0.63 9.8 0.0 3.6 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 FANCI_S2 PF14676.1 KNZ79006.1 - 0.21 11.4 9.1 0.65 9.8 0.1 4.9 5 0 0 5 5 5 0 FANCI solenoid 2 HEAT_EZ PF13513.1 KNZ79006.1 - 0.3 11.6 9.7 2.4 8.7 0.1 5.9 4 1 1 5 5 5 0 HEAT-like repeat RRM_1 PF00076.17 KNZ79007.1 - 2e-24 85.0 0.1 7.4e-13 47.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ79007.1 - 1e-18 67.0 0.0 4.1e-09 36.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ79007.1 - 3.1e-16 58.9 0.0 4.4e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KNZ79007.1 - 0.0002 21.0 0.0 0.0074 16.0 0.0 2.5 2 0 0 2 2 2 1 Limkain b1 RRM_3 PF08777.6 KNZ79007.1 - 0.026 14.3 0.1 0.3 10.9 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Mito_carr PF00153.22 KNZ79008.1 - 2.8e-70 232.0 0.9 8.6e-24 83.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Transket_pyr PF02779.19 KNZ79009.1 - 6.8e-65 217.8 0.0 1.2e-64 217.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KNZ79009.1 - 5.5e-54 182.9 0.0 1.7e-53 181.2 0.0 1.8 2 0 0 2 2 2 1 Dehydrogenase E1 component EAP30 PF04157.11 KNZ79010.1 - 1.7e-28 99.3 0.0 2.2e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KNZ79010.1 - 3.4e-23 81.2 0.0 6.2e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 KNZ79010.1 - 3.4e-05 22.8 3.4 0.11 11.5 0.7 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 KNZ79010.1 - 0.003 17.3 3.1 0.041 13.7 2.5 2.3 1 1 1 2 2 2 2 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 KNZ79010.1 - 0.19 11.2 3.3 1.6 8.3 0.0 3.0 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger MFS_1 PF07690.11 KNZ79011.1 - 3.4e-13 49.0 40.4 7.4e-10 38.0 1.9 3.1 1 1 2 3 3 3 2 Major Facilitator Superfamily Pectinesterase PF01095.14 KNZ79012.1 - 2.1e-24 85.6 0.0 8.2e-21 73.8 0.0 2.1 2 0 0 2 2 2 2 Pectinesterase Bradykinin PF06753.7 KNZ79012.1 - 0.091 12.2 4.5 0.1 12.1 2.2 1.8 2 0 0 2 2 2 0 Bradykinin UBN2_3 PF14244.1 KNZ79013.1 - 0.00019 21.0 0.5 0.0023 17.4 0.4 2.0 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type MatE PF01554.13 KNZ79014.1 - 0.00055 19.5 16.3 0.014 15.0 2.3 3.4 3 1 0 3 3 3 3 MatE FcoT PF10862.3 KNZ79014.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 FcoT-like thioesterase domain SKG6 PF08693.5 KNZ79015.1 - 0.0088 15.3 0.2 0.027 13.7 0.2 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Plasmodium_Vir PF05795.6 KNZ79015.1 - 0.032 13.4 1.3 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Helitron_like_N PF14214.1 KNZ79016.1 - 1.8e-06 27.8 0.1 2.4e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 KNZ79017.1 - 2.9e-107 358.7 0.0 3.7e-107 358.4 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ79017.1 - 0.003 17.1 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 KNZ79017.1 - 0.057 13.5 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.10 KNZ79017.1 - 0.081 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KNZ79017.1 - 0.1 12.0 0.1 0.23 10.9 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ribonuc_L-PSP PF01042.16 KNZ79018.1 - 4.7e-33 113.5 0.0 5.5e-33 113.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP gag-asp_proteas PF13975.1 KNZ79019.1 - 0.0011 18.6 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ79019.1 - 0.0025 18.2 0.0 0.0064 16.9 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease WD40 PF00400.27 KNZ79021.1 - 1.2e-11 43.9 12.7 3.6e-07 29.8 0.3 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat 7TMR-HDED PF07697.6 KNZ79021.1 - 0.082 12.6 0.1 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 7TM-HD extracellular DZR PF12773.2 KNZ79021.1 - 1.3 8.8 14.8 2.7 7.8 10.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon Peptidase_S10 PF00450.17 KNZ79022.1 - 4.9e-85 286.1 0.1 9.8e-84 281.9 0.1 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KNZ79022.1 - 4.4e-07 30.0 0.0 2.6e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ79022.1 - 0.0046 16.7 0.0 0.028 14.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family GMC_oxred_N PF00732.14 KNZ79023.1 - 5.3e-52 176.8 0.0 8.1e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ79023.1 - 2e-29 102.7 0.0 1.3e-28 100.1 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase tRNA-synt_1c PF00749.16 KNZ79024.1 - 2.7e-78 262.8 0.0 1.1e-77 260.7 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain zf-UBR PF02207.15 KNZ79025.1 - 3.6e-16 58.6 15.7 3.6e-16 58.6 10.9 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 KNZ79025.1 - 1.2e-12 47.3 0.4 2.9e-12 46.1 0.3 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.4 KNZ79025.1 - 0.0025 17.0 0.0 0.0051 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL APH PF01636.18 KNZ79026.1 - 7.9e-16 58.5 0.3 2.7e-15 56.7 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ79026.1 - 0.00066 19.3 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KNZ79026.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KNZ79026.1 - 0.014 14.4 0.1 0.036 13.1 0.0 1.7 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KNZ79026.1 - 0.019 14.1 0.0 0.035 13.2 0.0 1.4 1 1 0 1 1 1 0 Protein kinase domain PCI PF01399.22 KNZ79027.1 - 1.4e-08 34.9 0.5 3.8e-08 33.5 0.4 1.8 1 1 0 1 1 1 1 PCI domain ATP-synt_E_2 PF08112.6 KNZ79027.1 - 0.0011 18.9 1.6 0.35 10.9 0.1 2.7 2 0 0 2 2 2 2 ATP synthase epsilon subunit Cortex-I_coil PF09304.5 KNZ79027.1 - 0.077 13.0 5.4 0.16 12.0 3.7 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF4404 PF14357.1 KNZ79027.1 - 0.99 9.8 7.1 0.22 11.9 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) zf-Apc11 PF12861.2 KNZ79028.1 - 9.8e-41 137.5 10.3 1.1e-40 137.3 7.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KNZ79028.1 - 6.4e-32 109.4 8.8 8e-32 109.1 6.1 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KNZ79028.1 - 1.8e-05 24.4 16.9 5.2e-05 22.9 11.3 2.3 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KNZ79028.1 - 0.0036 17.0 10.6 0.039 13.6 7.7 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KNZ79028.1 - 0.0054 16.7 5.3 0.0054 16.7 3.7 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KNZ79028.1 - 0.058 12.9 2.7 0.097 12.2 1.9 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 KNZ79028.1 - 0.15 11.7 13.9 0.8 9.4 9.6 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PSP1 PF04468.7 KNZ79029.1 - 8.3e-32 109.0 1.1 1.4e-31 108.3 0.8 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DHC_N1 PF08385.7 KNZ79030.1 - 3.3e-186 620.1 1.2 3.3e-186 620.1 0.9 2.5 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 RicinB_lectin_2 PF14200.1 KNZ79032.1 - 2.2e-24 85.8 2.4 2.1e-13 50.5 0.1 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KNZ79032.1 - 8.6e-08 32.2 0.1 0.00018 21.5 0.0 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain PepSY PF03413.14 KNZ79032.1 - 0.052 14.1 0.1 0.72 10.5 0.0 2.3 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain RicinB_lectin_2 PF14200.1 KNZ79033.1 - 6.3e-19 68.2 1.5 2.6e-14 53.4 1.1 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KNZ79033.1 - 0.0068 16.4 0.3 0.7 9.9 0.0 2.5 1 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Acid_PPase PF12689.2 KNZ79034.1 - 9.2e-53 178.3 0.0 6.5e-26 90.9 0.0 1.9 2 0 0 2 2 2 2 Acid Phosphatase Glyco_transf_15 PF01793.11 KNZ79035.1 - 2e-133 444.4 9.4 2.8e-133 443.9 6.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase p450 PF00067.17 KNZ79036.1 - 3.1e-58 197.4 0.0 3.6e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2160 PF09928.4 KNZ79037.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2160) RVT_3 PF13456.1 KNZ79038.1 - 0.027 14.2 0.0 0.027 14.2 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase-like Sec7_N PF12783.2 KNZ79039.1 - 3.7e-34 117.5 1.9 4.1e-33 114.1 0.7 2.9 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KNZ79039.1 - 2.7e-06 26.8 0.0 4.6e-05 22.8 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) CAP PF00188.21 KNZ79040.1 - 0.0033 17.8 0.4 0.0065 16.9 0.3 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ArgK PF03308.11 KNZ79040.1 - 0.26 10.0 1.0 0.37 9.5 0.7 1.1 1 0 0 1 1 1 0 ArgK protein RFXA_RFXANK_bdg PF15289.1 KNZ79041.1 - 0.068 13.3 0.3 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain DUF4208 PF13907.1 KNZ79041.1 - 0.11 12.7 0.8 0.21 11.8 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) F-box PF00646.28 KNZ79042.1 - 9.5e-07 28.3 0.7 4e-06 26.3 0.5 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KNZ79042.1 - 7.9e-05 22.3 0.4 7.9e-05 22.3 0.3 1.9 2 0 0 2 2 2 1 F-box-like EOS1 PF12326.3 KNZ79043.1 - 8.5e-14 51.4 7.0 1.7e-12 47.2 4.9 2.4 1 1 0 1 1 1 1 N-glycosylation protein F-box-like PF12937.2 KNZ79044.1 - 0.00088 18.9 0.2 0.00088 18.9 0.1 2.3 3 0 0 3 3 3 1 F-box-like 2OG-FeII_Oxy_2 PF13532.1 KNZ79045.1 - 5.5e-24 85.0 0.0 7.2e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nop14 PF04147.7 KNZ79046.1 - 0.33 8.8 14.8 0.056 11.3 7.3 1.7 2 0 0 2 2 2 0 Nop14-like family TEX19 PF15553.1 KNZ79046.1 - 0.51 10.1 4.3 1.4 8.7 3.0 1.8 1 0 0 1 1 1 0 Testis-expressed protein 19 Radial_spoke PF04712.7 KNZ79046.1 - 0.68 8.6 11.4 1.1 7.8 7.9 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Ycf1 PF05758.7 KNZ79046.1 - 1.7 6.2 2.0 2.6 5.6 1.4 1.1 1 0 0 1 1 1 0 Ycf1 Nucleo_P87 PF07267.6 KNZ79046.1 - 1.9 7.0 2.6 3.4 6.2 1.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Paf1 PF03985.8 KNZ79046.1 - 3.8 6.1 13.1 6.8 5.3 9.1 1.3 1 0 0 1 1 1 0 Paf1 Nucleoplasmin PF03066.10 KNZ79046.1 - 3.8 7.0 21.2 9.4 5.7 14.7 1.6 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 KNZ79046.1 - 5 6.6 15.1 11 5.5 10.5 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.6 KNZ79046.1 - 8.4 4.3 5.9 15 3.5 4.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.9 KNZ79046.1 - 9 5.7 12.5 1.8 8.0 5.5 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Piwi PF02171.12 KNZ79047.1 - 5e-83 278.5 0.0 7.1e-83 278.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KNZ79047.1 - 9e-17 60.6 0.0 1.6e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KNZ79047.1 - 1.9e-13 49.5 0.3 4.9e-13 48.2 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) AcetylCoA_hydro PF02550.10 KNZ79048.1 - 1.5e-42 145.6 0.0 2e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 KNZ79048.1 - 1.4e-33 115.7 0.0 1.9e-27 95.7 0.0 2.4 2 0 0 2 2 2 2 Acetyl-CoA hydrolase/transferase C-terminal domain Terpene_synth_C PF03936.11 KNZ79049.1 - 1.4e-08 34.3 0.0 1.8e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain HMG_box PF00505.14 KNZ79050.1 - 1.9e-10 40.8 0.1 4.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KNZ79050.1 - 0.0031 17.8 0.2 0.0095 16.2 0.0 1.8 2 0 0 2 2 2 1 HMG-box domain Sds3 PF08598.6 KNZ79050.1 - 0.076 12.5 0.8 0.12 11.9 0.6 1.2 1 0 0 1 1 1 0 Sds3-like adh_short PF00106.20 KNZ79052.1 - 2.4e-06 27.5 0.1 5.2e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase DUF1128 PF06569.6 KNZ79052.1 - 0.036 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) CBFD_NFYB_HMF PF00808.18 KNZ79053.1 - 0.0019 18.2 0.0 0.0054 16.7 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NOA36 PF06524.7 KNZ79053.1 - 0.72 9.0 9.6 1.1 8.4 6.6 1.3 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.8 KNZ79053.1 - 2.9 7.6 19.5 5.9 6.6 13.5 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit STE PF02200.11 KNZ79054.1 - 3.6e-53 178.3 0.1 6e-53 177.6 0.0 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2_4 PF13894.1 KNZ79054.1 - 1.2e-10 40.9 6.3 0.00018 21.5 0.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KNZ79054.1 - 1.6e-09 37.5 15.3 5e-05 23.3 1.3 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KNZ79054.1 - 6.1e-09 35.7 12.9 4e-08 33.1 2.6 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KNZ79054.1 - 0.00026 21.0 3.0 0.04 14.0 0.2 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KNZ79054.1 - 0.0098 16.0 4.6 0.3 11.3 0.7 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KNZ79054.1 - 0.12 12.4 0.9 0.27 11.4 0.7 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 KNZ79054.1 - 5.6 6.7 6.0 4.8 6.9 0.2 2.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Pkinase PF00069.20 KNZ79055.1 - 3.4e-36 124.7 0.0 4.5e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79055.1 - 2.9e-29 101.9 0.0 3.6e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ79055.1 - 2.4e-05 23.4 0.0 3.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KNZ79055.1 - 0.0024 17.2 0.0 0.0042 16.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KNZ79055.1 - 0.021 13.9 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ79055.1 - 0.037 13.7 0.4 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1275 PF06912.6 KNZ79056.1 - 1.1e-14 54.0 5.8 1.4e-14 53.7 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2231 PF09990.4 KNZ79056.1 - 0.019 15.2 0.1 0.019 15.2 0.1 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) MFS_1 PF07690.11 KNZ79056.1 - 0.14 10.8 10.0 0.36 9.4 1.2 2.2 2 0 0 2 2 2 0 Major Facilitator Superfamily Pkinase PF00069.20 KNZ79057.1 - 5.5e-14 51.9 0.0 1.9e-13 50.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79057.1 - 0.016 14.3 0.0 0.076 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase SNARE_assoc PF09335.6 KNZ79058.1 - 1.2e-14 54.5 15.7 1.3e-14 54.4 6.0 2.8 3 0 0 3 3 3 2 SNARE associated Golgi protein Pkinase PF00069.20 KNZ79061.1 - 4.1e-35 121.1 0.0 7e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79061.1 - 5.8e-32 110.7 0.0 1e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Patatin PF01734.17 KNZ79061.1 - 4.5e-12 46.3 0.1 4.3e-11 43.1 0.1 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase Kinase-like PF14531.1 KNZ79061.1 - 0.0051 15.8 0.0 0.0093 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ79061.1 - 0.008 15.9 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KNZ79061.1 - 0.018 14.4 0.1 0.74 9.1 0.0 2.9 3 0 0 3 3 3 0 RIO1 family Kdo PF06293.9 KNZ79061.1 - 0.043 12.8 0.0 0.83 8.6 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family K1377 PF15352.1 KNZ79062.1 - 0.081 10.8 0.6 0.083 10.8 0.4 1.0 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy TEX19 PF15553.1 KNZ79062.1 - 0.096 12.5 0.2 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 SNF2_N PF00176.18 KNZ79066.1 - 4.5e-74 248.9 0.1 9.2e-74 247.9 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KNZ79066.1 - 6.9e-40 135.4 0.7 6.9e-40 135.4 0.5 2.4 3 0 0 3 3 3 1 SLIDE HAND PF09110.6 KNZ79066.1 - 1.7e-28 99.2 0.2 1.7e-28 99.2 0.1 3.5 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 KNZ79066.1 - 2e-14 53.1 0.0 5.9e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ79066.1 - 1.6e-07 31.3 2.7 9.9e-07 28.7 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KNZ79066.1 - 0.00048 19.6 0.0 0.0015 18.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 KNZ79066.1 - 0.00069 19.5 0.0 0.021 14.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain Myb_DNA-bind_6 PF13921.1 KNZ79066.1 - 1.2 9.2 8.1 0.5 10.5 0.2 3.3 3 0 0 3 3 3 0 Myb-like DNA-binding domain EcKinase PF02958.15 KNZ79074.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase zf-CCHC PF00098.18 KNZ79080.1 - 0.0013 18.5 3.9 0.0013 18.5 2.7 3.4 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_3 PF13917.1 KNZ79080.1 - 0.18 11.5 13.7 0.079 12.7 1.8 2.9 2 1 1 3 3 3 0 Zinc knuckle Mito_fiss_reg PF05308.6 KNZ79080.1 - 2.1 7.6 7.0 3.1 7.0 4.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator SNF2_N PF00176.18 KNZ79082.1 - 6.9e-75 251.6 0.2 3.8e-74 249.1 0.1 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNZ79082.1 - 1e-13 50.9 0.0 3e-13 49.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ79082.1 - 2.2e-09 37.4 0.1 8.4e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KNZ79082.1 - 0.0072 15.1 0.5 0.075 11.8 0.2 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 IER PF05760.7 KNZ79082.1 - 2 8.2 8.1 7.5 6.3 1.2 2.3 2 0 0 2 2 2 0 Immediate early response protein (IER) UBN2_2 PF14227.1 KNZ79086.1 - 0.0028 17.2 0.3 0.17 11.4 0.0 2.3 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KNZ79086.1 - 0.036 13.6 0.1 0.063 12.8 0.1 1.4 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF1510 PF07423.6 KNZ79087.1 - 0.035 13.4 9.3 0.041 13.2 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nha1_C PF08619.5 KNZ79087.1 - 0.12 11.6 11.0 0.14 11.4 7.6 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DDHD PF02862.12 KNZ79087.1 - 0.13 12.0 2.4 0.16 11.7 1.6 1.1 1 0 0 1 1 1 0 DDHD domain Nop14 PF04147.7 KNZ79087.1 - 0.22 9.4 15.9 0.23 9.3 11.0 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2201_N PF13203.1 KNZ79087.1 - 0.22 10.6 2.9 0.27 10.3 2.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain TFIIA PF03153.8 KNZ79087.1 - 0.34 10.7 10.6 0.39 10.5 7.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.7 KNZ79087.1 - 1.6 7.9 12.4 2.2 7.4 8.6 1.4 1 0 0 1 1 1 0 NOA36 protein Nop25 PF09805.4 KNZ79087.1 - 6.1 6.9 17.3 8.6 6.4 12.0 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) NAD_binding_4 PF07993.7 KNZ79088.1 - 5.5e-14 51.7 0.0 1e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KNZ79088.1 - 0.0021 18.3 0.1 0.0057 16.8 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Fip1 PF05182.8 KNZ79088.1 - 0.1 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Fip1 motif PLAC8 PF04749.12 KNZ79089.1 - 2.4e-14 53.7 0.9 4.1e-14 53.0 0.6 1.3 1 1 0 1 1 1 1 PLAC8 family DUF1349 PF07081.6 KNZ79090.1 - 6.6e-09 35.3 0.0 9.8e-09 34.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) SOG2 PF10428.4 KNZ79091.1 - 0.74 8.3 3.7 0.86 8.1 2.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein WD40 PF00400.27 KNZ79094.1 - 2e-05 24.2 3.2 0.084 12.7 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.1 KNZ79094.1 - 0.00031 20.2 0.0 0.0033 16.9 0.0 2.6 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 KNZ79094.1 - 0.0054 16.9 0.2 46 4.4 0.0 4.5 5 0 0 5 5 5 0 PQQ-like domain BBS1 PF14779.1 KNZ79094.1 - 0.0065 15.4 1.7 0.27 10.1 0.0 3.4 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.1 KNZ79094.1 - 0.016 14.9 0.1 4.9 6.9 0.0 3.5 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PTCRA PF15028.1 KNZ79094.1 - 0.03 13.8 0.3 0.27 10.8 0.0 2.3 2 0 0 2 2 2 0 Pre-T-cell antigen receptor PQQ PF01011.16 KNZ79094.1 - 0.12 11.9 0.1 8.3 6.1 0.0 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat DUF4568 PF15132.1 KNZ79096.1 - 0.014 14.6 1.7 0.016 14.3 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) RVP_2 PF08284.6 KNZ79096.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease AAA_5 PF07728.9 KNZ79097.1 - 5e-66 220.6 0.0 4.9e-29 100.8 0.0 4.0 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 KNZ79097.1 - 0.0019 18.3 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain GNVR PF13807.1 KNZ79097.1 - 0.046 13.4 0.0 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase DUF3886 PF13025.1 KNZ79097.1 - 0.2 11.6 3.7 0.57 10.1 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) DUF258 PF03193.11 KNZ79097.1 - 0.22 10.6 0.0 0.43 9.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NAD_binding_6 PF08030.7 KNZ79098.1 - 5.3e-36 123.8 0.0 9.6e-36 123.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KNZ79098.1 - 2.1e-23 82.2 0.0 4.8e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KNZ79098.1 - 6.9e-15 55.2 5.6 6.9e-15 55.2 3.8 2.5 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KNZ79098.1 - 1.4e-05 25.0 0.0 3.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KNZ79098.1 - 0.1 13.2 0.0 1.8 9.1 0.0 2.5 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain Cation_ATPase_C PF00689.16 KNZ79098.1 - 0.21 11.1 10.5 0.074 12.5 5.1 1.8 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus PrgI PF12666.2 KNZ79098.1 - 0.66 10.1 6.1 0.11 12.6 0.5 2.4 2 0 0 2 2 2 0 PrgI family protein Glyco_hydro_28 PF00295.12 KNZ79099.1 - 2.6e-39 135.0 0.8 4.7e-39 134.2 0.5 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.8 KNZ79099.1 - 0.19 10.8 5.3 0.025 13.7 0.8 1.6 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) HTH_23 PF13384.1 KNZ79100.1 - 0.00019 20.9 0.1 0.00035 20.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 KNZ79100.1 - 0.0016 18.5 0.1 0.0044 17.1 0.0 1.7 1 1 1 2 2 2 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 KNZ79100.1 - 0.0042 16.2 0.0 0.0085 15.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_Crp_2 PF13545.1 KNZ79100.1 - 0.0046 16.7 0.1 0.013 15.3 0.0 1.8 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain GerE PF00196.14 KNZ79100.1 - 0.014 14.6 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.11 KNZ79100.1 - 0.029 13.6 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4_2 PF08281.7 KNZ79100.1 - 0.034 13.6 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.1 KNZ79100.1 - 0.039 13.3 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.7 KNZ79100.1 - 0.041 13.4 0.0 0.091 12.3 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Crp PF00325.15 KNZ79100.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_Tnp_4 PF13613.1 KNZ79100.1 - 0.085 12.4 0.1 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_28 PF13518.1 KNZ79100.1 - 0.09 12.8 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.7 KNZ79100.1 - 0.098 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.1 KNZ79100.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3703 PF12487.3 KNZ79100.1 - 2.3 7.9 6.9 7 6.3 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3703) DUF1534 PF07551.6 KNZ79101.1 - 0.061 12.8 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1534) Zn_clus PF00172.13 KNZ79102.1 - 0.00034 20.4 11.3 0.00076 19.3 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.13 KNZ79102.1 - 0.035 13.8 0.1 0.063 12.9 0.1 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper Iso_dh PF00180.15 KNZ79103.1 - 9.8e-71 238.5 0.0 1.2e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-C2HC_2 PF13913.1 KNZ79104.1 - 0.53 10.0 4.6 1.3 8.7 3.2 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Sod_Fe_C PF02777.13 KNZ79105.1 - 4e-37 126.2 0.1 6.6e-37 125.5 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KNZ79105.1 - 2e-31 108.1 3.4 2e-31 108.1 2.4 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AsmA_1 PF13109.1 KNZ79105.1 - 0.02 14.1 0.0 0.22 10.7 0.0 2.0 1 1 1 2 2 2 0 AsmA-like C-terminal region p450 PF00067.17 KNZ79106.1 - 4.3e-49 167.2 0.0 7.9e-48 163.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Actino_peptide PF14408.1 KNZ79108.1 - 0.12 12.3 0.1 0.39 10.6 0.1 1.9 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes p450 PF00067.17 KNZ79110.1 - 3.3e-47 161.0 0.0 4.5e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UPF0560 PF10577.4 KNZ79111.1 - 0.056 11.7 0.2 0.066 11.4 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Pyr_redox PF00070.22 KNZ79112.1 - 7.9e-13 48.6 0.0 1.4e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KNZ79112.1 - 9e-07 28.9 0.0 1.6e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KNZ79112.1 - 0.0069 15.3 0.0 0.42 9.4 0.0 2.1 1 1 1 2 2 2 2 Lycopene cyclase protein NAD_binding_7 PF13241.1 KNZ79112.1 - 0.045 14.0 0.0 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Mqo PF06039.10 KNZ79112.1 - 0.098 10.8 0.0 0.15 10.2 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Velvet PF11754.3 KNZ79114.1 - 4e-32 111.4 0.0 5.7e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Velvet factor RVP_2 PF08284.6 KNZ79116.1 - 0.0013 18.6 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Thaumatin PF00314.12 KNZ79118.1 - 9.1e-62 208.2 8.1 1e-61 208.0 5.6 1.0 1 0 0 1 1 1 1 Thaumatin family Glucan_synthase PF02364.10 KNZ79119.1 - 0 1334.8 0.0 0 1334.4 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KNZ79119.1 - 7.2e-39 132.3 0.0 1.9e-38 130.9 0.0 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Pkinase PF00069.20 KNZ79120.1 - 9.9e-16 57.6 0.1 1.1e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79120.1 - 2.6e-08 33.2 0.0 3.4e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ79120.1 - 0.001 18.0 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DAO PF01266.19 KNZ79123.1 - 2.3e-43 148.5 1.8 4.5e-43 147.5 1.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ79123.1 - 3.5e-05 22.8 0.3 0.0065 15.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KNZ79123.1 - 7.2e-05 22.7 0.2 0.00016 21.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KNZ79123.1 - 0.00011 22.5 0.1 0.0047 17.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KNZ79123.1 - 0.00068 19.5 0.4 0.11 12.2 0.5 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 KNZ79123.1 - 0.0014 17.8 0.0 0.25 10.4 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase NAD_binding_9 PF13454.1 KNZ79123.1 - 0.017 14.9 0.9 0.091 12.5 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KNZ79123.1 - 0.017 13.7 0.3 0.046 12.3 0.4 1.5 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 KNZ79123.1 - 0.047 12.7 0.5 0.08 12.0 0.3 1.2 1 0 0 1 1 1 0 Thi4 family Ald_Xan_dh_C PF01315.17 KNZ79123.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Saccharop_dh PF03435.13 KNZ79123.1 - 2 7.2 4.7 0.22 10.4 0.2 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase CLN3 PF02487.12 KNZ79124.1 - 1.1e-39 136.4 3.5 5.5e-36 124.2 2.4 3.1 1 1 0 1 1 1 1 CLN3 protein DsrH PF04077.7 KNZ79125.1 - 0.017 14.8 0.1 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 DsrH like protein HAMP PF00672.20 KNZ79125.1 - 0.034 14.3 0.2 9.1 6.5 0.0 3.0 2 2 0 2 2 2 0 HAMP domain API5 PF05918.6 KNZ79126.1 - 0.0085 14.6 2.3 0.015 13.8 1.6 1.4 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) DUF2201_N PF13203.1 KNZ79126.1 - 0.25 10.4 4.0 3.3 6.8 0.9 2.4 2 0 0 2 2 2 0 Putative metallopeptidase domain zf-HC5HC2H PF13771.1 KNZ79126.1 - 0.28 11.3 1.6 0.54 10.4 1.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain TB2_DP1_HVA22 PF03134.14 KNZ79127.1 - 8.1e-27 92.8 5.8 1.2e-26 92.3 4.0 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Gemini_mov PF01708.11 KNZ79127.1 - 0.13 11.8 0.3 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Geminivirus putative movement protein Helitron_like_N PF14214.1 KNZ79129.1 - 1.1e-15 57.8 0.3 1.3e-15 57.6 0.2 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Gemini_AL1 PF00799.15 KNZ79129.1 - 0.025 14.4 0.3 0.028 14.2 0.2 1.2 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain PIF1 PF05970.9 KNZ79131.1 - 1.5e-26 93.2 0.0 1.8e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 KNZ79131.1 - 0.0063 16.3 0.0 0.0072 16.1 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KNZ79131.1 - 0.012 15.1 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KNZ79131.1 - 0.064 12.4 0.0 0.081 12.1 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein Sdh5 PF03937.11 KNZ79131.1 - 0.075 12.7 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase Torsin PF06309.6 KNZ79131.1 - 0.076 12.8 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Torsin Viral_helicase1 PF01443.13 KNZ79131.1 - 0.12 11.8 0.1 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2791 PF10923.3 KNZ79131.1 - 0.17 10.4 0.0 0.19 10.2 0.0 1.0 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) PIF1 PF05970.9 KNZ79132.1 - 1.3e-31 109.9 0.1 1.6e-31 109.5 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 KNZ79132.1 - 0.016 15.3 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Fungal_trans PF04082.13 KNZ79133.1 - 1.4e-15 56.9 0.0 2.8e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ79133.1 - 9.5e-05 22.2 13.8 0.00022 21.0 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CLN3 PF02487.12 KNZ79134.1 - 6.1e-65 219.5 2.4 1.1e-62 212.1 1.7 2.1 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 KNZ79134.1 - 0.019 13.7 22.6 0.11 11.1 14.8 2.4 1 1 1 2 2 2 0 Major Facilitator Superfamily WD40 PF00400.27 KNZ79135.1 - 1.2e-52 173.9 15.3 7.2e-09 35.2 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KNZ79135.1 - 2e-06 26.2 0.5 0.69 7.9 0.0 4.9 3 1 2 5 5 5 2 Nucleoporin Nup120/160 F-box-like PF12937.2 KNZ79135.1 - 5.9e-06 25.9 0.1 1.6e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.1 KNZ79135.1 - 0.0043 16.5 0.0 0.03 13.7 0.0 2.4 2 1 0 2 2 2 1 PQQ-like domain K-box PF01486.12 KNZ79137.1 - 0.085 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 K-box region PP2C PF00481.16 KNZ79138.1 - 4.2e-32 111.5 0.0 5.6e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KNZ79138.1 - 2e-11 43.9 0.0 3.9e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KNZ79138.1 - 5.3e-06 26.0 0.0 9.5e-06 25.1 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3513 PF12026.3 KNZ79138.1 - 0.037 13.5 0.0 0.09 12.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) STAG PF08514.6 KNZ79139.1 - 3.6e-30 104.1 3.5 6.4e-30 103.2 0.2 3.0 2 1 1 3 3 3 1 STAG domain HEAT_2 PF13646.1 KNZ79139.1 - 2.9e-08 33.8 0.0 0.00032 20.9 0.0 3.0 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 KNZ79139.1 - 6.2e-05 22.7 0.0 7.3 6.9 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat DUF422 PF04240.7 KNZ79139.1 - 0.064 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF422) ATG16 PF08614.6 KNZ79141.1 - 0.1 12.4 2.4 0.22 11.3 1.7 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Fungal_trans PF04082.13 KNZ79143.1 - 2.1e-07 30.0 0.0 8e-07 28.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ79143.1 - 0.02 14.7 2.2 0.048 13.5 1.5 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP1_OBG PF01018.17 KNZ79144.1 - 2.5e-37 127.9 3.1 2.5e-25 88.9 1.0 2.5 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 KNZ79144.1 - 3.9e-18 65.4 0.0 7.1e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KNZ79144.1 - 0.00019 20.7 0.0 0.00037 19.7 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KNZ79144.1 - 0.00023 20.6 0.0 0.0025 17.2 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KNZ79144.1 - 0.00029 21.3 0.0 0.00066 20.1 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein cobW PF02492.14 KNZ79144.1 - 0.0019 17.6 0.1 0.61 9.5 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 KNZ79144.1 - 0.002 17.9 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.1 KNZ79144.1 - 0.0076 16.5 0.2 0.28 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KNZ79144.1 - 0.0088 16.3 0.1 0.027 14.7 0.1 1.8 1 0 0 1 1 1 1 ABC transporter Arf PF00025.16 KNZ79144.1 - 0.017 14.3 0.1 0.82 8.8 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family ArgK PF03308.11 KNZ79144.1 - 0.036 12.8 0.2 0.45 9.2 0.1 2.1 2 0 0 2 2 2 0 ArgK protein AAA_17 PF13207.1 KNZ79144.1 - 0.097 13.4 0.3 0.91 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain ThiF PF00899.16 KNZ79144.1 - 0.11 12.3 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 0 ThiF family AAA_21 PF13304.1 KNZ79144.1 - 0.17 11.8 0.0 0.58 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pterin_bind PF00809.17 KNZ79145.1 - 6.2e-43 146.6 0.0 1.8e-42 145.1 0.0 1.8 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KNZ79145.1 - 8.4e-32 109.5 0.0 4.1e-30 104.1 0.0 2.2 1 1 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Peptidase_S24 PF00717.18 KNZ79146.1 - 1.3e-08 34.3 0.0 2.1e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like RNase_H PF00075.19 KNZ79147.1 - 5.1e-08 33.3 0.1 8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 RNase H Herpes_gI PF01688.12 KNZ79147.1 - 0.055 12.5 0.7 0.091 11.8 0.5 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I FB_lectin PF07367.6 KNZ79148.1 - 2.1e-39 134.3 0.1 2.5e-39 134.1 0.1 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin NTP_transf_2 PF01909.18 KNZ79149.1 - 7.1e-07 29.4 0.0 1.8e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 KNZ79149.1 - 7.5e-07 29.0 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF892 PF05974.7 KNZ79150.1 - 0.033 13.9 1.9 0.08 12.7 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Complex1_LYR PF05347.10 KNZ79150.1 - 0.12 12.1 1.3 0.23 11.3 0.9 1.4 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Snapin_Pallidin PF14712.1 KNZ79150.1 - 0.2 11.9 6.0 0.12 12.7 2.2 2.0 2 0 0 2 2 2 0 Snapin/Pallidin Syntaxin-6_N PF09177.6 KNZ79150.1 - 0.21 12.0 4.7 0.2 12.0 0.6 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF2051 PF09738.4 KNZ79150.1 - 1.1 8.4 8.7 0.66 9.2 0.5 2.1 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) OmpH PF03938.9 KNZ79150.1 - 7.2 6.5 12.5 0.46 10.4 1.4 2.2 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Glyco_hydro_31 PF01055.21 KNZ79151.1 - 4.4e-14 52.1 0.1 5.3e-14 51.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KNZ79151.1 - 0.00055 19.7 0.1 0.00077 19.2 0.0 1.4 1 1 0 1 1 1 1 Galactose mutarotase-like DAP PF15228.1 KNZ79152.1 - 0.17 12.6 14.7 0.9 10.3 10.2 2.2 1 1 0 1 1 1 0 Death-associated protein DUF605 PF04652.11 KNZ79152.1 - 7 5.9 15.6 7.9 5.7 10.8 1.0 1 0 0 1 1 1 0 Vta1 like Ribosomal_L28e PF01778.12 KNZ79153.1 - 1.1e-24 87.0 0.0 1.4e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Polysacc_deac_1 PF01522.16 KNZ79154.1 - 0.00011 21.7 0.2 0.00041 19.9 0.2 2.0 1 1 0 1 1 1 1 Polysaccharide deacetylase gag_pre-integrs PF13976.1 KNZ79155.1 - 6.6e-07 28.8 0.0 1.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 KNZ79155.1 - 0.0016 18.5 0.1 0.0033 17.5 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Helitron_like_N PF14214.1 KNZ79157.1 - 3.6e-60 202.8 0.1 4.9e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Herpes_Helicase PF02689.9 KNZ79159.1 - 3.6e-05 21.7 0.0 3.8e-05 21.6 0.0 1.0 1 0 0 1 1 1 1 Helicase CDP-OH_P_transf PF01066.16 KNZ79161.1 - 9.8e-18 64.3 0.6 9.8e-18 64.3 0.4 2.7 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Peptidase_M17 PF00883.16 KNZ79162.1 - 2.5e-113 378.0 0.0 3.7e-113 377.5 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 KNZ79162.1 - 5.1e-09 35.9 0.2 1.1e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Adeno_shaft PF00608.12 KNZ79162.1 - 0.11 12.1 0.1 0.27 10.8 0.1 1.7 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) bZIP_1 PF00170.16 KNZ79163.1 - 6.5e-10 38.8 8.0 6.5e-10 38.8 5.5 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KNZ79163.1 - 1.2e-05 24.9 11.5 1.2e-05 24.9 8.0 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 KNZ79163.1 - 0.029 14.6 8.3 0.041 14.1 5.8 1.4 1 1 0 1 1 1 0 bZIP Maf transcription factor CENP-H PF05837.7 KNZ79163.1 - 0.045 13.9 0.8 0.061 13.5 0.6 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) XkdW PF09636.5 KNZ79163.1 - 0.049 13.4 1.4 0.085 12.7 0.9 1.3 1 0 0 1 1 1 0 XkdW protein THP2 PF09432.5 KNZ79163.1 - 0.056 13.3 0.1 0.063 13.1 0.1 1.1 1 0 0 1 1 1 0 Tho complex subunit THP2 COX5A PF02284.11 KNZ79164.1 - 9.4e-42 141.3 0.1 1.5e-41 140.6 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va LOH1CR12 PF10158.4 KNZ79164.1 - 0.019 14.7 0.2 3.9 7.2 0.1 2.1 1 1 1 2 2 2 0 Tumour suppressor protein CK2S PF15011.1 KNZ79164.1 - 0.057 13.2 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate PspA_IM30 PF04012.7 KNZ79164.1 - 0.088 12.1 0.2 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 PspA/IM30 family RNase_H PF00075.19 KNZ79165.1 - 1.7e-15 57.5 0.0 6e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 RNase H RdRP PF05183.7 KNZ79166.1 - 6e-06 25.2 0.1 8.9e-06 24.6 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase CBM_21 PF03370.8 KNZ79167.1 - 9.1e-18 64.2 2.7 5.8e-13 48.8 0.0 3.3 2 1 0 2 2 2 2 Putative phosphatase regulatory subunit Serglycin PF04360.7 KNZ79167.1 - 0.036 13.7 0.4 0.036 13.7 0.2 1.9 2 0 0 2 2 2 0 Serglycin SelP_N PF04592.9 KNZ79167.1 - 0.29 10.5 3.3 0.44 9.8 2.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RNase_H PF00075.19 KNZ79168.1 - 0.0046 17.3 0.0 0.0065 16.8 0.0 1.2 1 0 0 1 1 1 1 RNase H CBM_3 PF00942.13 KNZ79168.1 - 0.018 15.0 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 Cellulose binding domain Pinin_SDK_memA PF04696.8 KNZ79170.1 - 1.2 8.7 6.0 2.2 7.9 4.2 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Vfa1 PF08432.5 KNZ79172.1 - 1.4e-27 96.8 23.0 9.3e-26 90.9 15.9 2.0 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Sporozoite_P67 PF05642.6 KNZ79172.1 - 0.027 12.3 2.0 0.031 12.1 1.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 KNZ79172.1 - 0.73 7.7 15.0 0.9 7.4 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 KNZ79172.1 - 0.87 8.9 12.8 1.2 8.4 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2457 PF10446.4 KNZ79172.1 - 5 5.7 19.3 7.4 5.1 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRM_1 PF00076.17 KNZ79173.1 - 2.7e-81 267.1 1.5 2.2e-19 68.8 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ79173.1 - 1.3e-55 185.2 0.3 4.4e-14 52.2 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ79173.1 - 6.2e-42 141.2 0.0 4.3e-12 45.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KNZ79173.1 - 3.9e-28 96.9 0.2 1.6e-27 94.9 0.2 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain OB_RNB PF08206.6 KNZ79173.1 - 0.00065 19.1 0.6 2.6 7.6 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 KNZ79173.1 - 0.0029 17.3 0.0 2.2 8.1 0.0 3.9 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KNZ79173.1 - 0.011 15.4 4.2 4.3 7.1 0.0 3.5 3 0 0 3 3 3 0 Limkain b1 CbiG_mid PF11761.3 KNZ79173.1 - 0.021 15.0 0.0 0.26 11.5 0.0 2.6 2 0 0 2 2 2 0 Cobalamin biosynthesis central region PNPase PF03726.9 KNZ79173.1 - 0.06 13.6 1.5 1.4 9.2 0.0 2.8 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF4407 PF14362.1 KNZ79173.1 - 0.41 9.5 4.5 0.38 9.6 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PABP PF00658.13 KNZ79175.1 - 2.5e-20 71.9 0.7 4.1e-20 71.2 0.5 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_1 PF00076.17 KNZ79175.1 - 5.5e-20 70.7 0.2 1.7e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ79175.1 - 2.7e-13 49.7 0.0 1.2e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ79175.1 - 1.3e-06 28.1 0.0 4.2e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldo_ket_red PF00248.16 KNZ79175.1 - 0.023 13.5 0.0 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 Aldo/keto reductase family PNPase PF03726.9 KNZ79175.1 - 0.045 14.0 0.6 4.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF4301 PF14134.1 KNZ79175.1 - 0.05 12.1 0.9 2.5 6.5 0.3 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4301) RRM_3 PF08777.6 KNZ79175.1 - 0.088 12.6 0.6 0.19 11.6 0.4 1.7 1 1 0 1 1 1 0 RNA binding motif ERp29 PF07749.7 KNZ79175.1 - 0.42 11.2 3.4 1.1 9.9 0.8 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain RRM_1 PF00076.17 KNZ79176.1 - 6.5e-20 70.5 0.1 1.6e-19 69.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ79176.1 - 5.6e-13 48.6 0.0 1.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ79176.1 - 1.2e-06 28.2 0.0 3.9e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldo_ket_red PF00248.16 KNZ79176.1 - 0.041 12.6 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Aldo/keto reductase family DUF3883 PF13020.1 KNZ79176.1 - 0.074 12.8 0.1 0.14 11.8 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3883) RRM_3 PF08777.6 KNZ79176.1 - 0.098 12.5 0.6 0.19 11.6 0.4 1.5 1 1 0 1 1 1 0 RNA binding motif DUF3484 PF11983.3 KNZ79179.1 - 0.65 10.8 3.3 1.7 9.5 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3484) RNase_H PF00075.19 KNZ79180.1 - 8.8e-17 61.6 1.2 1.8e-16 60.6 0.3 1.8 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.1 KNZ79180.1 - 0.0019 18.4 0.3 0.0042 17.3 0.2 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase MarR PF01047.17 KNZ79180.1 - 0.014 15.0 0.0 4.9 6.9 0.0 2.6 2 0 0 2 2 2 0 MarR family DUF2250 PF10007.4 KNZ79180.1 - 0.046 13.6 1.0 0.2 11.5 0.2 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Glyoxalase_4 PF13669.1 KNZ79185.1 - 0.082 12.9 0.1 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RRM_1 PF00076.17 KNZ79187.1 - 1.8e-40 136.3 0.5 2.4e-20 71.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ79187.1 - 8.7e-30 102.5 0.1 8.3e-15 54.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KNZ79187.1 - 2.1e-18 65.7 0.8 9.6e-18 63.6 0.1 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.1 KNZ79187.1 - 3.3e-18 65.2 0.0 4.8e-11 42.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KNZ79187.1 - 0.00028 20.6 0.5 0.31 10.9 0.1 2.4 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 KNZ79187.1 - 0.035 13.8 0.0 0.75 9.6 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KNZ79187.1 - 0.07 12.8 0.5 14 5.5 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 OB_RNB PF08206.6 KNZ79187.1 - 0.16 11.4 0.9 5.6 6.5 0.2 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Methyltransf_16 PF10294.4 KNZ79190.1 - 5.1e-44 149.7 0.0 6.8e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KNZ79190.1 - 0.0013 19.2 0.0 0.0031 18.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ79190.1 - 0.025 13.9 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KNZ79190.1 - 0.056 13.4 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain COX15-CtaA PF02628.10 KNZ79191.1 - 1.2e-94 316.6 9.8 1.4e-94 316.3 6.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein BolA PF01722.13 KNZ79192.1 - 1.1e-14 54.1 0.0 1.6e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Stb3 PF10330.4 KNZ79192.1 - 0.031 13.9 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative Sin3 binding protein YIF1 PF03878.10 KNZ79194.1 - 1.8e-67 227.0 0.3 2.2e-67 226.7 0.2 1.0 1 0 0 1 1 1 1 YIF1 ADH_N PF08240.7 KNZ79196.1 - 6.2e-27 93.5 1.3 1.3e-26 92.4 0.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KNZ79196.1 - 1.2e-18 66.9 0.2 2e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 KNZ79196.1 - 0.0068 16.2 0.2 0.063 13.0 0.1 2.2 2 0 0 2 2 2 1 ThiF family 2-Hacid_dh_C PF02826.14 KNZ79196.1 - 0.028 13.5 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACBP PF00887.14 KNZ79197.1 - 6.3e-27 93.0 0.1 9.7e-27 92.4 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein GvpK PF05121.7 KNZ79197.1 - 0.13 12.0 0.3 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 Gas vesicle protein K Peptidase_M43 PF05572.8 KNZ79198.1 - 4.5e-35 120.5 0.7 1e-19 70.6 0.0 2.4 2 0 0 2 2 2 2 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 KNZ79198.1 - 8.8e-11 42.4 2.7 1.3e-06 28.9 0.2 2.4 2 0 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KNZ79198.1 - 1.6e-09 38.0 3.0 3.3e-06 27.1 0.0 3.4 1 1 1 3 3 3 2 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KNZ79198.1 - 4.7e-08 33.2 2.2 7.5e-05 22.8 0.1 2.5 2 0 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KNZ79198.1 - 7.6e-06 25.5 5.3 0.0022 17.5 0.2 2.7 2 2 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 KNZ79198.1 - 0.00039 19.8 2.2 0.088 12.1 0.1 2.4 2 0 0 2 2 2 2 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 KNZ79198.1 - 0.0017 18.1 1.8 0.0055 16.4 0.1 2.4 2 1 0 2 2 2 1 Matrixin DDE_Tnp_ISL3 PF01610.12 KNZ79198.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Transposase Glu-tRNAGln PF02686.10 KNZ79200.1 - 1.6e-05 24.5 0.1 4.3e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit dUTPase PF00692.14 KNZ79201.1 - 1.3e-40 137.8 0.0 1.5e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 dUTPase Tho2 PF11262.3 KNZ79202.1 - 2.3e-60 204.1 0.0 4.5e-60 203.2 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KNZ79202.1 - 1.1e-26 92.4 0.0 2.5e-26 91.2 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit GTP_cyclohydroI PF01227.17 KNZ79203.1 - 2.9e-75 251.4 0.7 3.6e-75 251.1 0.5 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KNZ79203.1 - 0.002 18.0 0.0 0.0056 16.5 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 KNZ79203.1 - 0.035 13.9 0.4 0.075 12.8 0.1 1.7 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain ABC_tran PF00005.22 KNZ79204.1 - 5.8e-20 71.9 0.0 1.2e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KNZ79204.1 - 8.9e-07 29.1 0.1 7.3e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 KNZ79204.1 - 0.00095 17.7 0.0 0.0019 16.7 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 KNZ79204.1 - 0.0012 18.0 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.1 KNZ79204.1 - 0.002 18.0 0.0 0.0052 16.6 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 KNZ79204.1 - 0.0089 15.2 0.0 0.01 15.0 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain IMS PF00817.15 KNZ79208.1 - 3e-26 91.9 0.0 5.1e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KNZ79208.1 - 1.5e-13 50.7 0.0 6.4e-12 45.5 0.0 2.4 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KNZ79208.1 - 0.0054 16.7 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif CIA30 PF08547.7 KNZ79209.1 - 1.3e-23 83.6 0.0 1.7e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 KNZ79209.1 - 0.079 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) Ras PF00071.17 KNZ79210.1 - 4.8e-52 175.6 0.2 5.6e-52 175.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ79210.1 - 7.7e-20 71.5 0.0 1.1e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ79210.1 - 3.2e-10 39.5 0.0 3.7e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KNZ79210.1 - 5.6e-07 29.1 0.0 1.1e-06 28.2 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KNZ79210.1 - 0.0055 16.6 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KNZ79210.1 - 0.12 11.5 0.1 0.13 11.3 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 KNZ79210.1 - 0.18 11.1 0.3 1.2 8.5 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 KNZ79210.1 - 0.19 11.2 1.7 1.7 8.0 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Pyr_redox_2 PF07992.9 KNZ79211.1 - 3.1e-29 102.2 1.6 5.1e-29 101.5 1.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KNZ79211.1 - 2.3e-15 55.9 0.1 5.5e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 KNZ79211.1 - 4.7e-10 39.7 4.1 1.6e-09 38.0 0.3 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNZ79211.1 - 2.3e-09 37.5 0.2 1.3e-05 25.3 0.0 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 KNZ79211.1 - 2.8e-07 30.1 0.0 7.1e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.1 KNZ79211.1 - 4.4e-07 30.1 0.0 9.4e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 KNZ79211.1 - 0.00011 21.1 0.0 0.075 11.9 0.0 2.4 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KNZ79211.1 - 0.0003 19.8 0.9 0.5 9.2 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase APG17 PF04108.7 KNZ79213.1 - 1e-35 123.3 21.3 5.9e-30 104.3 10.4 2.8 2 1 0 2 2 2 2 Autophagy protein Apg17 IncA PF04156.9 KNZ79213.1 - 0.012 15.1 4.6 0.012 15.1 3.2 2.7 2 1 1 3 3 3 0 IncA protein DUF2664 PF10867.3 KNZ79213.1 - 0.15 12.6 4.3 0.53 10.9 0.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) ABC_membrane PF00664.18 KNZ79214.1 - 3.9e-65 219.9 29.5 3.9e-33 115.0 6.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KNZ79214.1 - 6.7e-51 172.1 0.0 1.9e-29 102.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KNZ79214.1 - 7e-09 35.2 1.6 0.0023 17.2 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KNZ79214.1 - 6.2e-08 32.9 0.1 0.024 14.6 0.0 3.9 2 2 1 3 3 3 2 AAA domain AAA_25 PF13481.1 KNZ79214.1 - 1.3e-05 24.6 0.1 0.031 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KNZ79214.1 - 2.3e-05 24.8 0.7 0.27 11.5 0.1 2.8 3 0 0 3 3 3 2 AAA domain ATP-synt_ab PF00006.20 KNZ79214.1 - 0.00014 21.4 0.0 0.11 11.9 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Miro PF08477.8 KNZ79214.1 - 0.00018 22.0 1.6 0.31 11.5 0.1 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KNZ79214.1 - 0.00047 19.6 0.6 0.13 11.7 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KNZ79214.1 - 0.0013 18.6 2.2 0.084 12.8 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KNZ79214.1 - 0.002 18.1 0.2 0.83 9.6 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.7 KNZ79214.1 - 0.0021 17.1 1.6 0.74 8.8 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin DUF258 PF03193.11 KNZ79214.1 - 0.0033 16.6 0.2 2.7 7.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 UPF0079 PF02367.12 KNZ79214.1 - 0.012 15.2 2.5 0.042 13.4 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 KNZ79214.1 - 0.019 14.5 4.5 2.5 7.5 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 KNZ79214.1 - 0.047 13.5 1.0 6 6.6 0.1 2.5 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 KNZ79214.1 - 0.05 13.2 2.5 0.082 12.5 0.2 2.2 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 KNZ79214.1 - 0.064 12.6 0.5 8.7 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain TrwB_AAD_bind PF10412.4 KNZ79214.1 - 0.084 11.4 1.9 2.8 6.4 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF4349 PF14257.1 KNZ79214.1 - 0.097 11.8 0.3 0.21 10.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) FtsK_SpoIIIE PF01580.13 KNZ79214.1 - 0.098 12.1 1.4 4.9 6.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KNZ79214.1 - 0.11 13.2 5.9 1.2 10.0 0.4 3.1 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KNZ79214.1 - 0.12 12.1 5.4 3.6 7.2 0.0 3.7 4 0 0 4 4 4 0 Archaeal ATPase AAA_22 PF13401.1 KNZ79214.1 - 0.21 11.7 5.6 12 6.0 0.1 3.6 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KNZ79214.1 - 0.25 11.5 0.2 37 4.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 KNZ79214.1 - 0.34 10.6 2.8 6 6.5 0.2 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.1 KNZ79214.1 - 0.36 9.2 0.0 0.72 8.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KNZ79214.1 - 0.37 9.5 2.5 9.3 5.0 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 KNZ79214.1 - 0.48 9.9 5.4 2.9 7.4 0.2 2.8 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 KNZ79214.1 - 0.85 8.5 2.2 35 3.2 0.0 3.0 4 0 0 4 4 4 0 AAA ATPase domain DUF87 PF01935.12 KNZ79214.1 - 1.8 8.3 5.0 0.78 9.5 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 ArgK PF03308.11 KNZ79214.1 - 3.4 6.3 6.3 7.6 5.2 0.1 2.6 3 0 0 3 3 3 0 ArgK protein MOZ_SAS PF01853.13 KNZ79215.1 - 3e-77 258.1 0.0 4.8e-77 257.4 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 KNZ79215.1 - 9.4e-16 57.2 22.5 1.7e-10 40.4 4.4 3.4 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.1 KNZ79215.1 - 0.048 12.9 12.2 0.34 10.2 0.9 3.5 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.17 KNZ79215.1 - 2.5 7.9 15.4 7.2 6.4 1.5 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 KNZ79215.1 - 5.9 7.0 8.1 2.1 8.4 1.9 2.7 2 0 0 2 2 2 0 C1-like domain DUF2360 PF10152.4 KNZ79216.1 - 0.0058 16.9 3.6 0.01 16.0 2.5 1.5 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) zf-CCHC_5 PF14787.1 KNZ79217.1 - 1.6 8.3 6.1 3 7.4 4.3 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 KNZ79217.1 - 1.7 8.6 7.5 3.2 7.8 5.2 1.5 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.6 KNZ79218.1 - 0.00052 19.9 0.2 0.00066 19.6 0.1 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KNZ79218.1 - 0.012 16.0 0.0 0.069 13.6 0.0 1.8 2 0 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.1 KNZ79218.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal tRNA_lig_CPD PF08302.6 KNZ79219.1 - 0.015 14.5 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain p450 PF00067.17 KNZ79221.1 - 2.8e-67 227.2 0.1 5.9e-67 226.1 0.1 1.4 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 KNZ79222.1 - 2.6e-55 187.3 0.0 3.8e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79222.1 - 1.7e-17 63.3 0.0 3.4e-17 62.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Med3 PF11593.3 KNZ79222.1 - 0.079 12.1 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2370 PF10176.4 KNZ79224.1 - 1.9e-20 73.2 2.0 1e-19 70.8 1.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) UPF0061 PF02696.9 KNZ79225.1 - 2.2e-91 306.6 0.0 3.4e-91 305.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family GDA1_CD39 PF01150.12 KNZ79227.1 - 1.1e-13 50.5 0.0 1.5e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DcpS_C PF11969.3 KNZ79228.1 - 3.4e-27 94.9 0.0 5.6e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KNZ79228.1 - 3.3e-19 69.2 0.0 6.4e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal FAD_binding_4 PF01565.18 KNZ79229.1 - 4.6e-19 68.2 0.1 1e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KNZ79229.1 - 2.9e-06 27.0 0.1 8e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like p450 PF00067.17 KNZ79233.1 - 1.2e-48 165.7 0.0 7.7e-36 123.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 HSP9_HSP12 PF04119.7 KNZ79234.1 - 5.5e-22 77.6 7.0 1e-21 76.7 4.7 1.5 2 0 0 2 2 2 1 Heat shock protein 9/12 DUF2263 PF10021.4 KNZ79235.1 - 2.1e-16 60.2 0.0 3.2e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) LRR_4 PF12799.2 KNZ79236.1 - 0.03 13.9 1.1 0.13 11.9 0.1 2.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Glyco_transf_4 PF13439.1 KNZ79236.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Polysacc_synt_4 PF04669.8 KNZ79237.1 - 4.8e-21 74.9 1.6 5.1e-20 71.6 1.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Meth_synt_1 PF08267.7 KNZ79237.1 - 0.011 15.0 0.7 0.013 14.8 0.5 1.2 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain DUF2491 PF10679.4 KNZ79237.1 - 0.012 14.5 0.2 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Myb_DNA-binding PF00249.26 KNZ79238.1 - 1.3e-07 31.5 0.2 2.4e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KNZ79238.1 - 0.0003 20.8 0.3 0.0003 20.8 0.2 2.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain TIMELESS PF04821.9 KNZ79239.1 - 7e-48 163.1 0.1 1.6e-47 161.9 0.1 1.7 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 KNZ79239.1 - 1.6e-16 60.3 5.8 1.6e-16 60.3 4.0 3.6 3 1 1 4 4 4 1 Timeless protein C terminal region bZIP_1 PF00170.16 KNZ79240.1 - 5.6e-06 26.2 6.3 0.0071 16.2 2.6 2.2 2 0 0 2 2 2 2 bZIP transcription factor Shugoshin_N PF07558.6 KNZ79240.1 - 0.0027 17.3 2.1 0.062 13.0 0.2 2.2 2 0 0 2 2 2 2 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.10 KNZ79240.1 - 0.063 13.1 14.5 0.055 13.2 2.3 2.7 3 0 0 3 3 3 0 Basic region leucine zipper Transaldolase PF00923.14 KNZ79241.1 - 7.7e-31 107.2 0.0 9.4e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Transaldolase Hydrolase_6 PF13344.1 KNZ79242.1 - 1.2e-31 108.6 0.0 4.6e-31 106.6 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KNZ79242.1 - 2.7e-13 50.8 0.0 3.2e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KNZ79242.1 - 3.9e-12 45.7 0.0 1e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 KNZ79242.1 - 2.7e-09 37.5 0.0 8.3e-06 26.1 0.0 2.6 2 2 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KNZ79242.1 - 0.0093 15.3 0.0 0.03 13.6 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Ribosomal_L7Ae PF01248.21 KNZ79242.1 - 0.047 13.2 0.1 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Peripla_BP_4 PF13407.1 KNZ79242.1 - 0.11 11.8 0.0 2.4 7.4 0.0 2.1 1 1 1 2 2 2 0 Periplasmic binding protein domain Ribosomal_L34e PF01199.13 KNZ79243.1 - 3.8e-38 129.6 3.0 5.2e-38 129.1 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e EndIII_4Fe-2S PF10576.4 KNZ79243.1 - 0.33 11.2 1.8 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III FhuF_C PF11575.3 KNZ79243.1 - 1.8 8.2 6.0 7.3 6.3 0.2 2.6 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain rve PF00665.21 KNZ79244.1 - 5e-05 23.3 0.0 5.2e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain DUF1136 PF06582.7 KNZ79244.1 - 0.053 13.2 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1136) ECH_C PF13766.1 KNZ79245.1 - 0.053 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region DUF3086 PF11285.3 KNZ79246.1 - 0.038 12.7 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Kei1 PF08552.6 KNZ79248.1 - 0.01 15.5 0.1 1.6 8.3 0.1 2.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 TPPK_C PF12555.3 KNZ79248.1 - 2.3 8.0 5.7 1.8 8.3 0.3 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal YtpI PF14007.1 KNZ79249.1 - 0.013 15.4 1.2 4.5 7.2 0.0 2.4 2 0 0 2 2 2 0 YtpI-like protein p450 PF00067.17 KNZ79250.1 - 1.9e-69 234.3 0.0 3.8e-69 233.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 RVT_1 PF00078.22 KNZ79252.1 - 0.041 13.2 0.0 0.041 13.2 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 KNZ79253.1 - 0.024 14.2 0.8 0.039 13.5 0.5 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase p450 PF00067.17 KNZ79255.1 - 1.2e-59 202.0 0.0 1.6e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CFEM PF05730.6 KNZ79256.1 - 6.8e-12 45.0 9.7 1.4e-11 44.0 6.7 1.6 1 0 0 1 1 1 1 CFEM domain Med21 PF11221.3 KNZ79256.1 - 0.18 11.7 1.6 0.26 11.2 1.1 1.1 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Ribosomal_L31e PF01198.14 KNZ79257.1 - 8.7e-31 105.4 0.3 1e-30 105.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L31e CDI PF02234.14 KNZ79258.1 - 0.014 15.1 1.1 4.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Baculo_PEP_C PF04513.7 KNZ79258.1 - 0.052 13.3 0.8 0.11 12.3 0.5 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1801 PF08818.6 KNZ79258.1 - 0.096 12.7 0.1 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DU1801) p450 PF00067.17 KNZ79259.1 - 1e-63 215.4 0.0 2.5e-62 210.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Usp PF00582.21 KNZ79260.1 - 1.3e-09 38.3 0.3 2.9e-09 37.2 0.2 1.6 1 1 0 1 1 1 1 Universal stress protein family ADPrib_exo_Tox PF03496.9 KNZ79260.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme Glyco_hydro_47 PF01532.15 KNZ79261.1 - 6e-130 433.9 0.0 6.8e-130 433.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MMR_HSR1 PF01926.18 KNZ79262.1 - 1.8e-11 43.9 0.0 4e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KNZ79262.1 - 1.7e-09 37.7 0.4 4.5e-06 26.5 0.0 2.6 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 KNZ79262.1 - 1.4e-08 34.0 0.0 1.9e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KNZ79262.1 - 4.3e-07 29.2 0.0 1.2e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 IIGP PF05049.8 KNZ79262.1 - 1.8e-06 27.0 0.0 4.2e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 KNZ79262.1 - 1e-05 25.8 0.0 3e-05 24.3 0.0 1.8 2 1 0 2 2 2 1 ABC transporter Septin PF00735.13 KNZ79262.1 - 1.6e-05 24.0 0.0 3.6e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Septin GBP PF02263.14 KNZ79262.1 - 3.4e-05 23.0 0.0 6.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain FtsK_SpoIIIE PF01580.13 KNZ79262.1 - 0.00024 20.6 0.0 0.0017 17.8 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 KNZ79262.1 - 0.00064 20.2 0.0 0.0014 19.1 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein DUF87 PF01935.12 KNZ79262.1 - 0.0011 18.8 0.1 0.0095 15.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF87 Viral_helicase1 PF01443.13 KNZ79262.1 - 0.0012 18.3 0.0 0.0063 16.0 0.0 1.9 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 KNZ79262.1 - 0.0074 15.7 0.1 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 KNZ79262.1 - 0.0088 15.6 0.8 3.3 7.1 0.1 2.6 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein T2SE PF00437.15 KNZ79262.1 - 0.017 14.0 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 KNZ79262.1 - 0.018 15.3 0.5 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KNZ79262.1 - 0.022 14.6 0.8 0.053 13.4 0.1 2.2 1 1 2 3 3 3 0 AAA domain AAA_22 PF13401.1 KNZ79262.1 - 0.026 14.6 0.0 0.079 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KNZ79262.1 - 0.028 13.8 0.0 0.088 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 KNZ79262.1 - 0.032 14.5 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 KNZ79262.1 - 0.038 13.4 0.8 1.6 8.1 0.2 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KNZ79262.1 - 0.047 13.6 0.1 0.42 10.5 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain cobW PF02492.14 KNZ79262.1 - 0.072 12.5 0.1 0.16 11.3 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Torsin PF06309.6 KNZ79262.1 - 0.08 12.8 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Torsin NB-ARC PF00931.17 KNZ79262.1 - 0.082 11.7 0.0 0.69 8.7 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain FeoB_N PF02421.13 KNZ79262.1 - 0.098 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B KaiC PF06745.8 KNZ79262.1 - 0.11 11.5 0.0 0.24 10.4 0.0 1.5 2 0 0 2 2 2 0 KaiC SRPRB PF09439.5 KNZ79262.1 - 0.14 11.3 0.0 0.35 10.0 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 KNZ79262.1 - 0.17 11.8 2.2 1 9.2 1.4 2.6 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 KNZ79262.1 - 0.21 12.3 1.4 0.39 11.5 0.2 1.9 2 2 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KNZ79263.1 - 2.1e-06 27.6 0.0 4.8e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KNZ79263.1 - 4.1e-05 23.4 0.2 0.45 10.3 0.0 2.8 2 1 0 3 3 3 2 Dynamin family DUF258 PF03193.11 KNZ79263.1 - 0.00011 21.4 0.0 0.0002 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KNZ79263.1 - 0.00024 20.2 0.0 0.00033 19.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Septin PF00735.13 KNZ79263.1 - 0.04 12.9 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Septin GBP PF02263.14 KNZ79263.1 - 0.071 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Nup54 PF13874.1 KNZ79264.1 - 2.4e-31 108.2 3.3 2.4e-31 108.2 2.3 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 KNZ79264.1 - 4.6e-31 107.4 144.7 2.8e-12 46.8 21.4 4.3 1 1 3 4 4 4 3 Nucleoporin FG repeat region Bacillus_HBL PF05791.6 KNZ79264.1 - 0.67 9.2 3.0 15 4.8 0.1 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF3509 PF12021.3 KNZ79264.1 - 8.7 6.1 7.8 2 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) AMNp_N PF10423.4 KNZ79265.1 - 0.069 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus WD40 PF00400.27 KNZ79267.1 - 2.7e-38 128.4 2.0 1.2e-08 34.4 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KNZ79267.1 - 1.9e-06 27.7 0.1 0.0072 16.0 0.0 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 KNZ79267.1 - 0.001 17.9 0.0 1.2 7.8 0.0 2.5 3 0 0 3 3 3 2 Coatomer WD associated region TFIIIC_delta PF12657.2 KNZ79267.1 - 0.0033 17.1 0.8 0.64 9.7 0.0 3.5 2 1 1 3 3 3 1 Transcription factor IIIC subunit delta N-term Apc4_WD40 PF12894.2 KNZ79267.1 - 0.0037 16.7 0.0 3.8 7.0 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 KNZ79267.1 - 0.019 14.6 0.1 4.1 7.1 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 KNZ79267.1 - 0.037 13.7 0.0 0.83 9.4 0.0 2.9 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Srg PF02118.16 KNZ79269.1 - 0.00047 19.6 0.3 0.00047 19.6 0.2 2.1 1 1 1 2 2 2 1 Srg family chemoreceptor Ctr PF04145.10 KNZ79269.1 - 0.093 12.7 0.3 0.093 12.7 0.2 2.1 2 0 0 2 2 2 0 Ctr copper transporter family Fungal_trans PF04082.13 KNZ79271.1 - 2.2e-16 59.5 0.6 3.5e-16 58.8 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ79271.1 - 1.7e-05 24.6 9.0 5.9e-05 22.8 6.3 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KNZ79273.1 - 5.9e-54 183.3 7.6 1.4e-26 93.1 1.5 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter AAA_16 PF13191.1 KNZ79273.1 - 1.2e-12 48.1 0.0 3.8e-12 46.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KNZ79273.1 - 7e-09 35.5 0.0 2.6e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KNZ79273.1 - 0.00022 21.3 0.0 0.0011 19.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KNZ79273.1 - 0.00025 20.8 0.2 0.0023 17.6 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 KNZ79273.1 - 0.0011 19.1 0.2 0.016 15.3 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KNZ79273.1 - 0.012 15.0 0.0 0.061 12.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KNZ79273.1 - 0.028 14.5 0.0 0.084 13.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KNZ79273.1 - 0.063 13.5 0.2 0.6 10.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 KNZ79273.1 - 0.065 11.9 0.7 4.9 5.8 0.0 2.3 2 0 0 2 2 2 0 ArgK protein AAA_5 PF07728.9 KNZ79273.1 - 0.093 12.4 0.1 2.2 8.0 0.0 3.1 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Miro PF08477.8 KNZ79273.1 - 0.1 13.0 0.0 0.54 10.7 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein ABC_tran PF00005.22 KNZ79273.1 - 0.11 12.8 0.1 0.86 9.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.9 KNZ79273.1 - 0.24 10.3 5.0 1.8 7.4 3.5 2.6 1 1 0 1 1 1 0 KAP family P-loop domain Pkinase_Tyr PF07714.12 KNZ79274.1 - 4.4e-24 84.9 0.0 6.5e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ79274.1 - 7.4e-23 81.0 0.0 1.2e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KNZ79274.1 - 0.036 13.0 0.0 0.063 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like TRI9 PF08195.6 KNZ79274.1 - 0.039 13.5 0.3 2 8.1 0.1 2.5 2 0 0 2 2 2 0 TRI9 protein FF PF01846.14 KNZ79274.1 - 0.1 12.5 0.2 0.52 10.3 0.0 2.1 1 1 1 2 2 2 0 FF domain NmrA PF05368.8 KNZ79275.1 - 2.8e-28 98.7 0.0 4e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KNZ79275.1 - 2.2e-10 40.8 0.0 5.1e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KNZ79275.1 - 1.1e-06 28.4 0.0 2.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KNZ79275.1 - 6.2e-06 26.2 0.1 1.8e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 KNZ79275.1 - 2.3e-05 23.9 0.0 4.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KNZ79275.1 - 0.0094 14.9 0.0 0.068 12.0 0.0 2.2 3 0 0 3 3 3 1 Male sterility protein PcrB PF01884.12 KNZ79275.1 - 0.054 12.7 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 PcrB family Polysacc_synt_2 PF02719.10 KNZ79275.1 - 0.071 11.9 0.0 0.16 10.7 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KNZ79275.1 - 0.16 10.6 0.0 0.59 8.7 0.0 2.0 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family ATP-synt PF00231.14 KNZ79276.1 - 2.6e-68 230.5 2.0 3.2e-68 230.1 1.4 1.1 1 0 0 1 1 1 1 ATP synthase MFS_1 PF07690.11 KNZ79277.1 - 1e-10 40.8 45.8 2.9e-07 29.5 20.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Na_H_Exchanger PF00999.16 KNZ79278.1 - 2.9e-59 200.5 38.4 2.9e-59 200.5 26.6 1.4 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family ADH_zinc_N PF00107.21 KNZ79279.1 - 3.7e-20 71.7 0.0 5.5e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ79279.1 - 1.3e-10 40.9 0.0 2.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 KNZ79279.1 - 0.00087 18.8 0.0 0.0023 17.5 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.14 KNZ79279.1 - 0.069 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.7 KNZ79280.1 - 2.1e-27 95.0 0.2 3.2e-27 94.4 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KNZ79280.1 - 5.6e-19 67.9 0.0 9.1e-19 67.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KNZ79280.1 - 0.0011 18.6 0.0 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.14 KNZ79280.1 - 0.13 11.4 0.0 0.33 10.0 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trs65 PF12735.2 KNZ79281.1 - 1.4e-25 90.2 5.6 1.9e-25 89.8 0.0 3.2 3 2 0 3 3 3 1 TRAPP trafficking subunit Trs65 Ank_2 PF12796.2 KNZ79282.1 - 2.5e-17 62.9 0.0 5e-10 39.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KNZ79282.1 - 1.7e-14 53.4 1.5 7.1e-05 22.9 0.1 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KNZ79282.1 - 8.8e-14 51.5 4.4 1.4e-07 31.8 0.2 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ79282.1 - 2.4e-12 45.8 0.2 0.013 15.7 0.0 4.7 4 1 1 5 5 5 3 Ankyrin repeat Ank PF00023.25 KNZ79282.1 - 3.8e-12 45.3 0.7 0.0086 15.8 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeat MARVEL PF01284.18 KNZ79282.1 - 0.0064 16.3 6.6 0.0064 16.3 4.6 1.9 2 0 0 2 2 2 1 Membrane-associating domain MMR_HSR1 PF01926.18 KNZ79283.1 - 7.4e-10 38.8 0.1 2.8e-09 36.9 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 KNZ79283.1 - 1.9e-09 36.9 0.0 5.6e-09 35.4 0.0 1.7 1 1 0 2 2 2 1 AIG1 family DUF258 PF03193.11 KNZ79283.1 - 2.9e-09 36.3 0.0 6.8e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 KNZ79283.1 - 1.5e-07 30.7 0.0 3.4e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Septin GBP PF02263.14 KNZ79283.1 - 5.9e-07 28.8 0.0 1.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KNZ79283.1 - 8.2e-06 25.7 2.8 0.01 15.6 0.1 2.8 2 1 1 3 3 3 2 Dynamin family ABC_tran PF00005.22 KNZ79283.1 - 1.3e-05 25.5 0.1 3.5e-05 24.1 0.0 1.8 2 1 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 KNZ79283.1 - 0.00099 18.6 0.0 0.0023 17.4 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain Miro PF08477.8 KNZ79283.1 - 0.0012 19.3 0.0 0.004 17.6 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 KNZ79283.1 - 0.0032 16.9 0.0 0.0065 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IIGP PF05049.8 KNZ79283.1 - 0.0033 16.2 0.1 0.0064 15.3 0.0 1.4 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) G-alpha PF00503.15 KNZ79283.1 - 0.0075 15.0 0.1 0.29 9.7 0.0 2.6 3 0 0 3 3 3 1 G-protein alpha subunit MobB PF03205.9 KNZ79283.1 - 0.011 15.4 0.2 0.055 13.1 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KNZ79283.1 - 0.014 15.2 0.1 0.03 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KNZ79283.1 - 0.016 15.5 0.5 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KNZ79283.1 - 0.019 14.4 0.1 0.091 12.2 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 KNZ79283.1 - 0.024 14.8 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KNZ79283.1 - 0.032 15.0 0.2 0.12 13.2 0.1 2.1 2 2 0 2 2 2 0 AAA domain FeoB_N PF02421.13 KNZ79283.1 - 0.053 12.7 0.1 0.38 10.0 0.0 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B GTP_EFTU PF00009.22 KNZ79283.1 - 0.077 12.4 2.3 0.42 10.0 0.1 2.9 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.17 KNZ79283.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF1732 PF08340.6 KNZ79283.1 - 0.25 11.1 5.6 0.054 13.3 1.3 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF1732) ATP_bind_1 PF03029.12 KNZ79283.1 - 0.34 10.4 1.3 0.9 9.0 0.1 2.2 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Rtf2 PF04641.7 KNZ79284.1 - 2.9e-09 36.5 8.8 8.2e-06 25.2 0.8 2.4 2 1 0 2 2 2 2 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 KNZ79284.1 - 5e-09 36.0 20.4 1.8e-05 24.6 1.0 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNZ79284.1 - 1.6e-08 34.1 19.2 1.3e-05 24.7 7.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ79284.1 - 6.8e-06 25.7 21.4 3.6e-05 23.3 7.0 2.9 2 1 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.1 KNZ79284.1 - 8e-05 22.3 18.0 0.015 15.1 0.9 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 KNZ79284.1 - 0.00016 21.2 18.9 0.027 14.1 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Atg14 PF10186.4 KNZ79284.1 - 0.0024 16.8 0.6 0.0024 16.8 0.4 1.7 2 0 0 2 2 1 1 UV radiation resistance protein and autophagy-related subunit 14 zf-RING_6 PF14835.1 KNZ79284.1 - 0.012 15.3 8.3 0.013 15.2 0.4 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Vps39_2 PF10367.4 KNZ79284.1 - 0.014 15.5 1.8 0.014 15.5 1.3 3.2 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_4 PF15227.1 KNZ79284.1 - 0.051 13.4 14.6 0.12 12.2 0.8 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DivIC PF04977.10 KNZ79284.1 - 0.12 11.9 2.5 0.33 10.4 1.7 1.7 1 0 0 1 1 1 0 Septum formation initiator zinc-ribbons_6 PF07191.7 KNZ79284.1 - 1.2 9.0 14.7 1.9 8.3 0.9 2.7 2 1 0 2 2 2 0 zinc-ribbons TFIIS_C PF01096.13 KNZ79284.1 - 2 8.1 0.0 2 8.1 0.0 3.7 5 0 0 5 5 5 0 Transcription factor S-II (TFIIS) LsmAD PF06741.8 KNZ79284.1 - 6.3 6.9 6.4 0.73 9.9 0.4 2.1 2 0 0 2 2 2 0 LsmAD domain zf-RING_UBOX PF13445.1 KNZ79284.1 - 7 6.4 14.0 16 5.2 0.2 2.7 2 0 0 2 2 2 0 RING-type zinc-finger MMR_HSR1 PF01926.18 KNZ79285.1 - 1.2e-08 34.9 0.0 3.1e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KNZ79285.1 - 1.7e-07 30.5 0.0 3.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KNZ79285.1 - 3.8e-06 26.8 0.3 0.12 12.2 0.0 2.9 2 1 1 3 3 3 2 Dynamin family ABC_tran PF00005.22 KNZ79285.1 - 1.3e-05 25.5 0.0 3.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AIG1 PF04548.11 KNZ79285.1 - 7.2e-05 21.9 0.0 0.00016 20.8 0.0 1.5 1 1 0 1 1 1 1 AIG1 family Septin PF00735.13 KNZ79285.1 - 0.00041 19.4 0.0 0.0011 18.0 0.0 1.7 2 0 0 2 2 2 1 Septin Miro PF08477.8 KNZ79285.1 - 0.0008 19.8 0.0 0.033 14.6 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein IIGP PF05049.8 KNZ79285.1 - 0.002 17.0 0.0 0.0034 16.2 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) GBP PF02263.14 KNZ79285.1 - 0.0036 16.4 0.0 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_22 PF13401.1 KNZ79285.1 - 0.0094 16.0 0.0 0.22 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KNZ79285.1 - 0.032 15.0 0.5 0.54 11.0 0.0 2.9 2 1 0 3 3 3 0 AAA domain AAA_29 PF13555.1 KNZ79285.1 - 0.038 13.5 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KNZ79285.1 - 0.043 13.6 0.1 0.28 11.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KNZ79285.1 - 0.094 12.1 0.1 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 KNZ79285.1 - 0.098 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain GBP PF02263.14 KNZ79286.1 - 2.3e-05 23.5 0.0 4.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 KNZ79287.1 - 1.5e-10 41.0 0.0 2.8e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KNZ79287.1 - 1.6e-08 33.9 0.1 2.7e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KNZ79287.1 - 6.3e-07 28.7 0.0 1.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KNZ79287.1 - 4.1e-06 26.7 0.4 0.041 13.7 0.0 2.6 1 1 2 3 3 3 2 Dynamin family ABC_tran PF00005.22 KNZ79287.1 - 0.00018 21.8 0.1 0.00033 20.9 0.0 1.7 1 1 0 1 1 1 1 ABC transporter Septin PF00735.13 KNZ79287.1 - 0.00024 20.1 0.0 0.00046 19.3 0.0 1.5 1 1 0 1 1 1 1 Septin AAA_10 PF12846.2 KNZ79287.1 - 0.0019 17.6 0.7 0.011 15.1 0.5 2.0 1 1 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 KNZ79287.1 - 0.0036 17.6 0.1 0.0084 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 KNZ79287.1 - 0.0086 16.5 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 KNZ79287.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 KNZ79287.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_33 PF13671.1 KNZ79287.1 - 0.023 14.5 0.0 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KNZ79287.1 - 0.028 13.9 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 KNZ79287.1 - 0.028 13.8 0.1 0.086 12.2 0.1 1.8 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Spore_IV_A PF09547.5 KNZ79287.1 - 0.041 12.5 0.1 0.12 11.0 0.0 1.6 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) FtsK_SpoIIIE PF01580.13 KNZ79287.1 - 0.049 13.1 0.1 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 KNZ79287.1 - 0.062 12.7 1.2 1.3 8.4 0.2 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF87 PF01935.12 KNZ79287.1 - 0.094 12.5 0.1 0.65 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 T2SE PF00437.15 KNZ79287.1 - 0.1 11.4 0.2 0.2 10.5 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KNZ79288.1 - 3.2e-09 36.7 0.6 5.6e-08 32.7 0.0 2.9 2 2 1 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KNZ79288.1 - 2e-06 27.7 2.9 0.0027 17.5 0.1 3.3 3 1 1 4 4 4 2 Dynamin family AIG1 PF04548.11 KNZ79288.1 - 2e-06 27.0 0.0 4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KNZ79288.1 - 3e-05 23.2 0.0 6.8e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KNZ79288.1 - 0.00022 21.6 0.0 0.0027 18.1 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein Septin PF00735.13 KNZ79288.1 - 0.00058 18.9 0.0 0.0013 17.8 0.0 1.6 1 0 0 1 1 1 1 Septin ABC_tran PF00005.22 KNZ79288.1 - 0.00092 19.5 0.1 0.0053 17.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter GBP PF02263.14 KNZ79288.1 - 0.0015 17.6 0.0 0.0048 15.9 0.0 1.8 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_10 PF12846.2 KNZ79288.1 - 0.0016 17.9 0.1 0.0054 16.1 0.0 1.8 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 KNZ79288.1 - 0.0069 16.5 0.0 0.041 14.0 0.0 2.3 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 KNZ79288.1 - 0.037 12.9 0.0 0.074 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 KNZ79288.1 - 0.056 13.3 0.1 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KNZ79288.1 - 0.082 13.1 0.1 0.53 10.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Aldo_ket_red PF00248.16 KNZ79289.1 - 1.6e-67 227.3 0.0 1.9e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AA_permease_2 PF13520.1 KNZ79290.1 - 2.4e-40 138.3 45.0 3.3e-40 137.9 30.6 1.5 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 KNZ79290.1 - 1.8e-06 26.6 41.7 8.9e-06 24.2 28.6 1.9 1 1 1 2 2 2 1 Amino acid permease Yip1 PF04893.12 KNZ79291.1 - 2.2e-06 27.2 25.8 3.1e-06 26.8 17.3 1.6 1 1 1 2 2 2 1 Yip1 domain YIF1 PF03878.10 KNZ79291.1 - 0.24 10.5 11.3 3.3 6.7 7.8 2.5 1 1 0 1 1 1 0 YIF1 DLH PF01738.13 KNZ79293.1 - 1.5e-21 76.6 0.0 1.8e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KNZ79293.1 - 0.00059 19.6 0.0 0.00092 18.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ79293.1 - 0.0033 17.3 0.0 0.0046 16.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 KNZ79293.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Pkinase PF00069.20 KNZ79294.1 - 3.2e-35 121.5 0.0 5.9e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79294.1 - 4.4e-29 101.3 0.0 2.6e-28 98.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ79294.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KNZ79294.1 - 0.017 14.8 0.1 0.062 13.0 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KNZ79294.1 - 0.05 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1180 PF06679.7 KNZ79295.1 - 0.11 12.3 0.7 0.25 11.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Borrelia_lipo_1 PF05714.6 KNZ79296.1 - 0.018 14.1 0.1 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein Lectin_N PF03954.9 KNZ79296.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Phos_pyr_kin PF08543.7 KNZ79298.1 - 4e-89 298.0 0.4 5.7e-89 297.5 0.3 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KNZ79298.1 - 2.8e-40 138.3 0.0 3.9e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 KNZ79298.1 - 4.4e-10 39.1 0.0 6.8e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 KNZ79298.1 - 0.00033 19.9 5.6 0.0011 18.1 0.3 3.2 2 1 0 2 2 2 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.12 KNZ79298.1 - 0.0026 17.0 1.8 0.0092 15.2 1.3 2.0 1 1 0 1 1 1 1 Carbohydrate kinase HhH-GPD PF00730.20 KNZ79299.1 - 1.3e-19 70.5 0.0 1.8e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KNZ79299.1 - 2.4e-08 33.2 0.0 6.4e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KNZ79299.1 - 0.017 15.2 0.7 0.15 12.2 0.0 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.4 KNZ79299.1 - 0.57 10.4 3.2 1.1 9.5 2.2 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III GPI-anchored PF10342.4 KNZ79301.1 - 0.00071 20.0 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Adeno_E3_CR2 PF02439.10 KNZ79301.1 - 0.016 14.7 0.9 0.039 13.5 0.6 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Herpes_gE PF02480.11 KNZ79301.1 - 0.039 12.2 0.0 0.054 11.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Podoplanin PF05808.6 KNZ79301.1 - 0.04 13.4 0.3 0.087 12.3 0.2 1.5 1 0 0 1 1 1 0 Podoplanin DUF1191 PF06697.7 KNZ79301.1 - 0.058 12.2 0.0 0.096 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Menin PF05053.8 KNZ79303.1 - 0.18 9.9 2.4 0.25 9.4 1.7 1.1 1 0 0 1 1 1 0 Menin KilA-N PF04383.8 KNZ79304.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 KilA-N domain DUF1011 PF06237.7 KNZ79304.1 - 0.028 14.3 0.2 8.4 6.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1011) Mannosyl_trans2 PF04188.8 KNZ79306.1 - 6.9e-05 21.9 9.9 8.1e-05 21.7 6.8 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF3270 PF11674.3 KNZ79306.1 - 1.1 9.3 2.8 0.86 9.6 1.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3270) APH PF01636.18 KNZ79307.1 - 1.8e-11 44.2 0.3 5.4e-11 42.6 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ79307.1 - 2.3e-05 24.0 0.0 3.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KNZ79307.1 - 0.0035 16.5 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain SNF2_N PF00176.18 KNZ79310.1 - 1.7e-30 105.9 0.0 2.7e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNZ79310.1 - 3.7e-14 52.3 0.0 8.3e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ79310.1 - 9.9e-05 22.2 0.0 0.00026 20.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KNZ79310.1 - 0.0049 16.3 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase DEAD PF00270.24 KNZ79312.1 - 4.8e-16 58.7 0.1 8.7e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Mnd1 PF03962.10 KNZ79312.1 - 0.076 12.6 2.9 0.17 11.5 2.0 1.5 1 0 0 1 1 1 0 Mnd1 family SecA_DEAD PF07517.9 KNZ79312.1 - 0.091 12.0 0.7 0.18 11.0 0.5 1.5 1 1 0 1 1 1 0 SecA DEAD-like domain SlyX PF04102.7 KNZ79312.1 - 0.28 11.5 4.4 0.59 10.5 1.4 2.6 1 1 1 2 2 2 0 SlyX Nucleoplasmin PF03066.10 KNZ79312.1 - 1.9 7.9 12.0 0.048 13.1 3.4 1.9 2 0 0 2 2 2 0 Nucleoplasmin IncA PF04156.9 KNZ79312.1 - 2 7.9 7.5 3.9 7.0 5.2 1.4 1 0 0 1 1 1 0 IncA protein Tet_JBP PF12851.2 KNZ79313.1 - 0.016 14.4 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Chromo PF00385.19 KNZ79316.1 - 3.6e-09 36.1 0.1 8.6e-09 34.9 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KNZ79316.1 - 0.057 13.1 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain ATP-gua_PtransN PF02807.10 KNZ79316.1 - 0.093 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, N-terminal domain NARP1 PF12569.3 KNZ79317.1 - 0.4 9.3 2.8 0.61 8.7 2.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 XRCC4 PF06632.7 KNZ79317.1 - 0.74 8.6 5.2 0.35 9.6 1.9 1.6 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Med3 PF11593.3 KNZ79317.1 - 4.9 6.2 10.0 7.6 5.6 6.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RdRP PF05183.7 KNZ79320.1 - 9.8e-153 509.9 0.0 1.4e-152 509.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Myb_DNA-bind_2 PF08914.6 KNZ79321.1 - 5.3e-08 32.5 0.7 2.3e-07 30.5 0.5 2.1 1 1 0 1 1 1 1 Rap1 Myb domain Gtr1_RagA PF04670.7 KNZ79322.1 - 1.4e-82 276.3 0.0 2e-82 275.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KNZ79322.1 - 1.4e-06 27.7 0.0 2.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 KNZ79322.1 - 0.00025 20.9 0.0 0.00052 19.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KNZ79322.1 - 0.00043 19.5 0.0 0.00072 18.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KNZ79322.1 - 0.0017 18.8 0.0 0.005 17.3 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Viral_helicase1 PF01443.13 KNZ79322.1 - 0.026 14.0 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF1033 PF06279.6 KNZ79322.1 - 0.15 11.8 0.3 22 4.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) DMRL_synthase PF00885.14 KNZ79323.1 - 1.3e-47 161.1 0.0 8.1e-28 96.9 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase SRP40_C PF05022.7 KNZ79324.1 - 1.3e-26 92.8 0.4 4e-26 91.3 0.3 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain Abhydrolase_6 PF12697.2 KNZ79325.1 - 1.5e-18 67.5 0.0 2.3e-18 66.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ79325.1 - 7.3e-09 35.5 0.0 1.4e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ79325.1 - 9.8e-07 28.5 0.0 6.8e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KNZ79325.1 - 0.00076 19.2 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 KNZ79325.1 - 0.0022 17.4 0.0 0.074 12.4 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase PGAP1 PF07819.8 KNZ79325.1 - 0.016 14.8 0.0 0.04 13.4 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein ATP_bind_3 PF01171.15 KNZ79327.1 - 1.1e-42 145.5 0.0 2e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.16 KNZ79327.1 - 0.0043 16.6 0.0 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase Glyco_transf_22 PF03901.12 KNZ79328.1 - 5e-73 246.4 29.3 6.3e-73 246.1 20.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family IDO PF01231.13 KNZ79328.1 - 0.033 12.6 0.0 0.047 12.1 0.0 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase Pyr_redox_2 PF07992.9 KNZ79329.1 - 3.4e-21 76.0 0.1 5.8e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 KNZ79329.1 - 8.8e-12 43.4 4.4 1.9e-05 23.5 1.2 2.4 2 0 0 2 2 2 2 EF hand Pyr_redox PF00070.22 KNZ79329.1 - 5.6e-10 39.4 5.1 1.2e-08 35.2 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_6 PF13405.1 KNZ79329.1 - 6.1e-09 35.0 2.0 0.00037 20.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KNZ79329.1 - 2.4e-08 33.4 3.2 0.0015 18.0 1.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KNZ79329.1 - 2.3e-07 29.8 2.6 0.0025 17.1 0.6 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KNZ79329.1 - 3.2e-07 30.3 2.1 7.8e-07 29.1 1.4 1.7 1 1 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.1 KNZ79329.1 - 4.6e-07 30.1 0.1 0.22 11.5 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KNZ79329.1 - 0.057 13.6 0.1 1.1 9.4 0.0 2.6 1 1 1 2 2 2 0 Putative NAD(P)-binding DUF3909 PF13077.1 KNZ79329.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) YTH PF04146.10 KNZ79330.1 - 6.1e-46 155.4 0.0 1e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain KH_1 PF00013.24 KNZ79331.1 - 3.6e-39 132.2 8.8 2.4e-14 52.7 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KNZ79331.1 - 1.4e-29 101.2 13.7 9.2e-10 37.9 0.9 3.7 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KNZ79331.1 - 8.8e-16 57.2 5.7 1.8e-05 24.2 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KNZ79331.1 - 3.6e-06 26.5 2.2 0.039 13.6 0.0 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KNZ79331.1 - 0.001 18.7 4.8 3.4 7.5 0.0 3.5 3 0 0 3 3 3 3 NusA-like KH domain Pex14_N PF04695.8 KNZ79331.1 - 0.046 13.7 2.9 4.2 7.4 0.4 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mito_fiss_reg PF05308.6 KNZ79331.1 - 1.1 8.5 5.0 1.4 8.2 0.3 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Brix PF04427.13 KNZ79332.1 - 6.5e-34 117.2 0.1 8.7e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain ROKNT PF08067.6 KNZ79332.1 - 0.057 13.2 0.5 0.16 11.8 0.3 1.7 1 0 0 1 1 1 0 ROKNT (NUC014) domain Mt_ATP-synt_D PF05873.7 KNZ79334.1 - 0.047 13.3 3.0 0.049 13.2 1.2 1.6 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Pox_A_type_inc PF04508.7 KNZ79334.1 - 0.26 11.1 5.6 0.4 10.5 0.0 3.7 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat Syntaxin-6_N PF09177.6 KNZ79334.1 - 0.54 10.7 13.3 0.043 14.2 2.9 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Prefoldin_2 PF01920.15 KNZ79334.1 - 2.2 8.1 12.4 4.6 7.0 0.2 3.3 1 1 1 2 2 2 0 Prefoldin subunit Atg14 PF10186.4 KNZ79334.1 - 8.1 5.2 22.3 0.76 8.6 4.9 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF16 PF01519.11 KNZ79334.1 - 8.6 6.6 8.1 22 5.3 5.5 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 TRAM_LAG1_CLN8 PF03798.11 KNZ79336.1 - 1.4e-22 80.2 12.5 5.1e-22 78.4 8.7 1.8 1 1 0 1 1 1 1 TLC domain Vps54 PF07928.7 KNZ79337.1 - 1.5e-51 174.0 1.3 4.5e-51 172.5 0.9 1.9 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 KNZ79337.1 - 0.00013 20.9 0.0 0.00024 20.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 KNZ79337.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Ecl1 PF12855.2 KNZ79338.1 - 0.0027 16.9 0.2 0.0067 15.6 0.1 1.6 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 KNZ79338.1 - 0.025 14.4 0.2 0.058 13.2 0.1 1.5 1 0 0 1 1 1 0 MYND finger WD40 PF00400.27 KNZ79339.1 - 5.6e-39 130.6 17.9 1.1e-08 34.6 0.1 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat DUF4221 PF13970.1 KNZ79339.1 - 0.18 11.0 0.0 0.56 9.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4221) Elongin_A PF06881.6 KNZ79340.1 - 1.3e-20 73.7 2.1 2.2e-20 73.0 1.4 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A cwf18 PF08315.7 KNZ79341.1 - 3.5e-27 95.4 10.9 8.9e-27 94.0 7.5 1.7 1 1 0 1 1 1 1 cwf18 pre-mRNA splicing factor ELH PF02323.10 KNZ79341.1 - 0.0066 15.6 1.8 0.011 14.9 1.3 1.5 1 1 0 1 1 1 1 Egg-laying hormone precursor HTH_37 PF13744.1 KNZ79342.1 - 0.15 11.8 0.2 0.27 11.0 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Pheromone PF08015.6 KNZ79343.1 - 2.2 9.1 11.8 2.1 9.2 5.3 2.3 1 1 1 2 2 2 0 Fungal mating-type pheromone tRNA-synt_1 PF00133.17 KNZ79345.1 - 9.7e-29 99.8 0.0 3.2e-17 61.7 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KNZ79345.1 - 4.7e-13 49.1 0.2 1.3e-12 47.7 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KNZ79345.1 - 5.1e-11 41.8 0.0 2e-07 30.0 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KNZ79345.1 - 1.5e-08 34.1 0.0 1.3e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain ArfGap PF01412.13 KNZ79346.1 - 1.1e-42 144.5 0.1 1.6e-42 143.9 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UNC-93 PF05978.11 KNZ79347.1 - 5.1e-13 48.7 7.2 5.1e-13 48.7 5.0 1.8 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KNZ79347.1 - 7.9e-12 44.5 14.3 7.9e-12 44.5 9.9 2.6 3 0 0 3 3 3 2 Major Facilitator Superfamily MFS_1 PF07690.11 KNZ79348.1 - 2.8e-15 55.8 32.0 2.8e-15 55.8 22.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KNZ79348.1 - 2.3e-11 43.4 6.4 2.3e-11 43.4 4.4 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF1201 PF06716.6 KNZ79348.1 - 0.14 11.9 0.1 0.14 11.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) Pkinase PF00069.20 KNZ79349.1 - 4e-70 235.9 0.0 4.8e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79349.1 - 1.4e-40 139.0 0.0 1.7e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ79349.1 - 4e-08 32.5 0.0 1.5e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KNZ79349.1 - 0.0006 19.6 2.2 0.11 12.2 0.1 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KNZ79349.1 - 0.019 14.0 0.1 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KNZ79349.1 - 0.12 11.6 0.1 0.3 10.4 0.0 1.7 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL DUF2244 PF10003.4 KNZ79350.1 - 0.71 9.2 10.3 2.6 7.4 0.2 2.3 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Pkinase PF00069.20 KNZ79352.1 - 1.2e-57 195.0 0.0 3e-57 193.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79352.1 - 3.3e-29 101.7 0.1 2.4e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KNZ79352.1 - 4.2e-05 22.6 0.5 0.00081 18.4 0.0 2.5 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 KNZ79352.1 - 0.0014 18.3 0.1 0.034 13.8 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KNZ79352.1 - 0.008 15.2 0.5 0.028 13.4 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KNZ79352.1 - 0.036 13.4 0.0 0.083 12.2 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Spindle_Spc25 PF08234.7 KNZ79353.1 - 2.8e-18 65.6 0.0 5.7e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 NCKAP5 PF15246.1 KNZ79353.1 - 0.0067 15.8 0.7 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 Nck-associated protein 5, Peripheral clock protein Atg14 PF10186.4 KNZ79353.1 - 0.015 14.2 8.7 0.02 13.8 6.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 KNZ79353.1 - 0.048 13.6 11.9 0.059 13.3 7.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) APG6 PF04111.7 KNZ79353.1 - 0.076 12.0 7.0 0.098 11.6 4.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 KNZ79353.1 - 0.5 10.0 6.4 0.73 9.4 4.4 1.3 1 0 0 1 1 1 0 Mnd1 family DUF4140 PF13600.1 KNZ79353.1 - 0.54 10.7 10.4 2.4 8.6 2.8 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 KNZ79353.1 - 1.1 8.7 4.7 0.32 10.5 1.1 1.7 2 0 0 2 2 2 0 Septum formation initiator GrpE PF01025.14 KNZ79353.1 - 2.6 7.5 8.8 0.56 9.7 3.0 2.0 1 1 1 2 2 2 0 GrpE DUF972 PF06156.8 KNZ79353.1 - 3.2 8.1 5.3 2 8.7 1.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TFIIS_C PF01096.13 KNZ79354.1 - 4.5e-18 64.5 5.9 6.5e-17 60.8 0.4 3.3 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KNZ79354.1 - 7.3e-09 35.1 1.4 5.8e-07 29.0 0.1 2.8 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 KNZ79354.1 - 7.8e-05 22.4 8.2 0.00036 20.2 0.1 2.9 2 1 0 2 2 2 1 Double zinc ribbon DUF2387 PF09526.5 KNZ79354.1 - 0.00026 20.8 3.0 0.0093 15.8 0.2 2.4 2 0 0 2 2 2 1 Probable metal-binding protein (DUF2387) Baculo_LEF5_C PF11792.3 KNZ79354.1 - 0.00061 19.1 0.5 0.00061 19.1 0.3 2.4 3 0 0 3 3 2 1 Baculoviridae late expression factor 5 C-terminal domain IBR PF01485.16 KNZ79354.1 - 0.00087 19.1 4.8 0.042 13.7 0.0 2.6 2 1 0 2 2 2 1 IBR domain zf-ribbon_3 PF13248.1 KNZ79354.1 - 0.00091 18.3 13.8 0.033 13.4 2.5 3.7 3 1 1 4 4 4 3 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KNZ79354.1 - 0.0025 17.5 11.3 0.032 14.0 1.6 3.2 2 2 1 3 3 3 1 Transposase zinc-ribbon domain Lar_restr_allev PF14354.1 KNZ79354.1 - 0.0034 17.6 6.7 0.62 10.4 0.3 2.5 2 1 0 2 2 2 2 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.1 KNZ79354.1 - 0.011 15.2 12.3 1.3 8.5 0.2 3.8 4 0 0 4 4 4 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.11 KNZ79354.1 - 0.013 15.1 1.6 2.6 7.8 0.0 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF164 PF02591.10 KNZ79354.1 - 0.016 15.0 3.3 8.4 6.3 0.0 3.7 4 0 0 4 4 4 0 Putative zinc ribbon domain zf-C4_Topoisom PF01396.14 KNZ79354.1 - 0.016 14.6 8.1 1.7 8.1 1.0 4.0 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger OrfB_Zn_ribbon PF07282.6 KNZ79354.1 - 0.021 14.4 6.6 1.3 8.6 0.1 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DNA_RNApol_7kD PF03604.8 KNZ79354.1 - 0.024 14.0 9.6 0.33 10.4 1.2 3.7 3 1 1 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit PHD PF00628.24 KNZ79354.1 - 0.028 14.1 6.9 0.95 9.2 0.6 2.5 2 1 0 2 2 2 0 PHD-finger zinc_ribbon_5 PF13719.1 KNZ79354.1 - 0.036 13.6 12.8 0.94 9.1 0.7 3.8 3 1 0 3 3 3 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 KNZ79354.1 - 0.061 13.1 10.4 0.088 12.6 0.2 3.3 2 1 1 3 3 3 0 PhnA Zinc-Ribbon zf-RING_3 PF14369.1 KNZ79354.1 - 0.071 13.1 7.0 48 4.0 0.2 4.1 3 1 1 4 4 4 0 zinc-finger UPF0547 PF10571.4 KNZ79354.1 - 0.081 12.6 11.5 2.1 8.0 0.2 3.6 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 HypA PF01155.14 KNZ79354.1 - 0.092 12.4 3.7 2.3 7.9 0.0 2.6 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 KNZ79354.1 - 0.096 12.6 11.2 13 5.7 0.0 4.0 3 1 1 4 4 4 0 Zinc ribbon domain Terminase_GpA PF05876.7 KNZ79354.1 - 0.12 10.6 2.7 0.21 9.8 0.5 2.0 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) TerY-C PF15616.1 KNZ79354.1 - 0.14 12.1 4.3 1.9 8.4 0.1 2.4 2 1 0 2 2 2 0 TerY-C metal binding domain zinc-ribbons_6 PF07191.7 KNZ79354.1 - 0.14 11.9 4.1 3.1 7.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbons Zn_ribbon_recom PF13408.1 KNZ79354.1 - 0.2 11.9 4.8 11 6.3 0.7 3.0 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zinc_ribbon_4 PF13717.1 KNZ79354.1 - 0.21 11.3 13.1 2 8.1 0.8 3.9 3 1 0 3 3 3 0 zinc-ribbon domain DUF2752 PF10825.3 KNZ79354.1 - 0.3 11.1 3.2 12 5.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) Cys_rich_CPCC PF14206.1 KNZ79354.1 - 0.32 10.5 4.4 1.6 8.3 0.1 2.5 2 1 0 2 2 2 0 Cysteine-rich CPCC zf-UDP PF14569.1 KNZ79354.1 - 0.34 10.6 0.1 0.34 10.6 0.1 2.1 2 1 0 2 2 2 0 Zinc-binding RING-finger DUF2296 PF10058.4 KNZ79354.1 - 0.42 10.3 5.1 22 4.8 0.0 3.8 4 0 0 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) Prok-RING_1 PF14446.1 KNZ79354.1 - 0.44 10.3 10.1 0.36 10.5 1.7 3.2 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 zf-FPG_IleRS PF06827.9 KNZ79354.1 - 0.56 9.9 7.9 6.3 6.5 0.9 3.2 3 1 1 4 4 3 0 Zinc finger found in FPG and IleRS CpXC PF14353.1 KNZ79354.1 - 0.61 10.0 6.3 57 3.6 0.0 3.7 3 1 0 3 3 3 0 CpXC protein RecR PF02132.10 KNZ79354.1 - 1.5 8.3 7.9 19 4.7 0.0 3.5 4 0 0 4 4 3 0 RecR protein Stc1 PF12898.2 KNZ79354.1 - 1.5 8.9 6.2 7.6 6.6 3.3 2.4 1 1 1 2 2 2 0 Stc1 domain Ribosomal_S27e PF01667.12 KNZ79354.1 - 1.7 8.2 9.9 1.4 8.5 1.7 3.3 3 1 0 3 3 2 0 Ribosomal protein S27 Rpr2 PF04032.11 KNZ79354.1 - 4.4 7.2 9.6 1.5 8.7 0.2 3.1 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RING_5 PF14634.1 KNZ79354.1 - 5.2 6.8 8.2 22 4.8 0.5 3.2 3 1 0 3 3 3 0 zinc-RING finger domain zf-ISL3 PF14690.1 KNZ79354.1 - 7.7 6.6 11.4 6.8 6.8 0.0 3.9 5 0 0 5 5 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 RRN7 PF11781.3 KNZ79354.1 - 9.9 5.7 11.0 60 3.2 2.7 3.8 3 1 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 TB2_DP1_HVA22 PF03134.14 KNZ79355.1 - 2e-29 101.1 6.8 2.9e-29 100.6 4.7 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family GtrA PF04138.9 KNZ79355.1 - 0.0055 16.6 5.9 0.0083 16.0 3.8 1.5 1 1 0 1 1 1 1 GtrA-like protein ABM PF03992.11 KNZ79356.1 - 4.1e-07 29.9 0.0 0.0042 17.0 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase VHS PF00790.14 KNZ79358.1 - 1.4e-40 138.1 1.2 9.1e-40 135.5 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KNZ79358.1 - 6.7e-17 61.1 6.8 1.2e-16 60.3 4.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 KNZ79358.1 - 0.00095 18.5 12.7 0.046 13.2 2.0 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif DZR PF12773.2 KNZ79358.1 - 0.35 10.7 6.7 3.5 7.5 2.5 2.3 1 1 1 2 2 2 0 Double zinc ribbon Vps35 PF03635.12 KNZ79360.1 - 0 1044.1 2.6 0 1043.9 1.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Cyt-b5 PF00173.23 KNZ79361.1 - 1.1e-21 76.4 0.4 2.2e-21 75.4 0.3 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KNZ79361.1 - 1.6e-08 34.9 20.5 1.6e-08 34.9 14.2 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Glyco_transf_90 PF05686.7 KNZ79363.1 - 1.5e-09 37.0 0.1 1.9e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Asp_protease_2 PF13650.1 KNZ79364.1 - 3.1e-07 30.7 0.0 4.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ79364.1 - 0.001 18.5 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Vps26 PF03643.10 KNZ79366.1 - 1.3e-09 37.2 0.3 2.9e-06 26.2 0.1 2.1 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 Glyco_transf_15 PF01793.11 KNZ79366.1 - 0.12 11.3 0.0 0.12 11.3 0.0 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase PGK PF00162.14 KNZ79367.1 - 5.4e-146 486.0 0.2 6.2e-146 485.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF1244 PF06844.6 KNZ79368.1 - 0.087 12.6 0.4 0.087 12.6 0.3 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1244) DUF2514 PF10721.4 KNZ79368.1 - 1.8 8.2 13.6 3 7.5 9.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Pheromone PF08015.6 KNZ79368.1 - 3.3 8.5 9.2 0.81 10.5 0.1 3.2 4 0 0 4 4 4 0 Fungal mating-type pheromone CAF-1_p150 PF11600.3 KNZ79368.1 - 7.8 5.8 27.4 0.1 11.9 14.1 1.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SDA1 PF05285.7 KNZ79370.1 - 6.6e-74 249.0 40.7 2.4e-38 132.2 4.9 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.7 KNZ79370.1 - 1e-22 80.1 0.1 7.8e-21 74.1 0.0 2.7 2 0 0 2 2 2 1 NUC130/3NT domain NUDIX PF00293.23 KNZ79371.1 - 5.5e-16 58.4 0.1 9.1e-15 54.4 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain DUF2790 PF10976.3 KNZ79371.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) PNK3P PF08645.6 KNZ79372.1 - 2.6e-44 150.4 0.0 4.4e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KNZ79372.1 - 5.6e-20 71.6 0.0 1.8e-16 60.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain HAD_2 PF13419.1 KNZ79372.1 - 0.00045 20.4 0.0 0.051 13.7 0.0 2.9 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase LNS2 PF08235.8 KNZ79372.1 - 0.021 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Zeta_toxin PF06414.7 KNZ79372.1 - 0.075 12.1 0.0 4.7 6.2 0.0 2.1 1 1 1 2 2 2 0 Zeta toxin Hydrolase_6 PF13344.1 KNZ79372.1 - 0.15 11.9 0.0 0.73 9.7 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase KTI12 PF08433.5 KNZ79372.1 - 0.2 10.8 0.2 0.77 8.9 0.2 1.8 1 1 1 2 2 2 0 Chromatin associated protein KTI12 GalP_UDP_transf PF01087.17 KNZ79373.1 - 6.4e-60 202.3 0.0 1e-59 201.6 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KNZ79373.1 - 3.1e-44 150.4 0.0 9.1e-44 148.9 0.0 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.3 KNZ79373.1 - 0.0057 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KNZ79373.1 - 0.013 16.0 0.6 0.084 13.4 0.2 2.4 2 1 0 2 2 2 0 HIT domain PRP38 PF03371.10 KNZ79374.1 - 1.6e-52 177.6 0.1 2e-52 177.2 0.1 1.1 1 0 0 1 1 1 1 PRP38 family DUF3652 PF12372.3 KNZ79374.1 - 0.047 13.3 0.1 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 Huntingtin protein region Ribosomal_L18e PF00828.14 KNZ79375.1 - 1.1e-16 61.3 0.0 2.1e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 GMC_oxred_N PF00732.14 KNZ79376.1 - 8.2e-63 212.2 0.0 1e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ79376.1 - 9e-35 120.0 0.0 1.5e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KNZ79376.1 - 0.0002 21.2 0.6 0.00064 19.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KNZ79376.1 - 0.00069 18.6 0.1 0.00099 18.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KNZ79376.1 - 0.00093 18.1 0.0 0.0018 17.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ79376.1 - 0.043 12.6 0.2 0.3 9.8 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KNZ79376.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family IPPT PF01715.12 KNZ79377.1 - 1.3e-57 194.7 0.1 5.7e-34 117.2 0.1 2.1 1 1 1 2 2 2 2 IPP transferase AAA_18 PF13238.1 KNZ79377.1 - 9.3e-06 25.9 0.1 0.0054 17.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KNZ79377.1 - 0.0004 21.1 0.0 0.001 19.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KNZ79377.1 - 0.0032 17.3 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KNZ79377.1 - 0.0065 15.9 0.0 0.032 13.6 0.0 2.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 KNZ79377.1 - 0.026 14.6 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.5 KNZ79377.1 - 0.055 12.6 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.24 KNZ79379.1 - 6.8e-41 139.5 0.0 1.6e-40 138.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCDHK_Adom3 PF10436.4 KNZ79379.1 - 1.1e-34 119.3 0.0 1.7e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KNZ79379.1 - 4.6e-14 52.0 0.0 2.5e-13 49.7 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.1 KNZ79379.1 - 2.2e-05 24.6 0.0 0.001 19.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KNZ79379.1 - 9.7e-05 22.1 0.0 0.00035 20.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KNZ79379.1 - 0.00022 21.2 0.0 0.00095 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 KNZ79379.1 - 0.00031 20.6 0.0 0.001 18.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KNZ79379.1 - 0.0011 17.9 0.0 0.0021 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KNZ79379.1 - 0.0026 18.5 0.1 0.0079 17.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain HATPase_c_3 PF13589.1 KNZ79379.1 - 0.0028 17.2 0.0 0.006 16.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_19 PF13245.1 KNZ79379.1 - 0.0095 15.6 0.1 0.028 14.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KNZ79379.1 - 0.013 15.5 0.0 0.04 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KNZ79379.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KNZ79379.1 - 0.022 13.8 0.0 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 KNZ79379.1 - 0.033 14.0 0.0 0.088 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KNZ79379.1 - 0.037 14.0 0.0 0.19 11.7 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 KNZ79379.1 - 0.044 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KNZ79379.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KNZ79379.1 - 0.06 12.5 0.0 0.21 10.7 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KNZ79379.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KNZ79379.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 KNZ79379.1 - 0.066 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KNZ79379.1 - 0.081 12.6 0.5 9.4 5.8 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase TIP49 PF06068.8 KNZ79379.1 - 0.096 11.3 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Pkinase PF00069.20 KNZ79380.1 - 3e-49 167.5 0.0 3e-49 167.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79380.1 - 9.3e-19 67.4 0.0 1.8e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ79380.1 - 0.0071 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ79380.1 - 8.4 5.9 5.4 0.55 9.7 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Ank_4 PF13637.1 KNZ79381.1 - 1.2e-14 54.3 0.1 1.3e-11 44.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KNZ79381.1 - 1.5e-14 54.0 0.0 4e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ79381.1 - 7.5e-14 50.7 0.1 5.2e-05 22.8 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KNZ79381.1 - 4.2e-13 48.1 0.0 6.9e-05 22.7 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat DnaJ PF00226.26 KNZ79381.1 - 2.3e-09 36.8 0.0 7.6e-09 35.1 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Ank_5 PF13857.1 KNZ79381.1 - 5.7e-09 35.9 0.1 0.019 15.1 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Zn_clus PF00172.13 KNZ79382.1 - 0.001 18.9 17.0 0.0014 18.4 11.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KNZ79383.1 - 6.2e-30 104.2 0.3 1.5e-29 102.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79383.1 - 3.9e-28 98.2 0.0 7.5e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase ING PF12998.2 KNZ79384.1 - 1.3e-05 25.4 5.8 1.6e-05 25.0 0.6 2.9 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Nuf2 PF03800.9 KNZ79385.1 - 9.7e-29 100.2 0.0 2.6e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 Nuf2 family Shugoshin_N PF07558.6 KNZ79385.1 - 0.015 15.0 0.0 0.015 15.0 0.0 4.3 4 1 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Spc7 PF08317.6 KNZ79385.1 - 0.018 13.7 40.1 0.045 12.4 15.5 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein GAS PF13851.1 KNZ79385.1 - 0.13 11.4 42.2 0.53 9.4 11.6 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 KNZ79385.1 - 0.14 12.5 35.3 0.18 12.1 0.3 4.5 1 1 2 4 4 4 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 KNZ79385.1 - 0.28 11.1 44.9 0.37 10.8 7.5 4.5 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF3584 PF12128.3 KNZ79385.1 - 0.65 7.2 40.4 1.3 6.2 28.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 KNZ79385.1 - 2.5 7.2 9.4 12 4.9 3.8 2.8 1 1 3 4 4 4 0 Reovirus sigma C capsid protein IncA PF04156.9 KNZ79385.1 - 2.7 7.5 42.7 0.42 10.1 7.2 2.7 1 1 1 2 2 2 0 IncA protein Med10 PF09748.4 KNZ79385.1 - 3.7 7.3 11.8 0.66 9.7 0.8 3.4 1 1 2 3 3 3 0 Transcription factor subunit Med10 of Mediator complex NPV_P10 PF05531.7 KNZ79385.1 - 4.9 7.4 12.9 0.6 10.4 1.2 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ERM PF00769.14 KNZ79385.1 - 6.8 6.1 47.4 0.015 14.8 5.4 3.2 1 1 0 2 2 2 0 Ezrin/radixin/moesin family Helicase_C PF00271.26 KNZ79386.1 - 2.5e-14 52.8 0.1 2e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.5 KNZ79386.1 - 1.4e-09 37.6 0.0 3.2e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 RQC domain Radical_SAM PF04055.16 KNZ79386.1 - 0.018 15.2 0.1 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Radical SAM superfamily DEAD PF00270.24 KNZ79387.1 - 5e-43 146.5 0.0 4.9e-42 143.2 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ79387.1 - 5.3e-23 80.6 0.0 2e-22 78.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 KNZ79387.1 - 0.00088 19.2 0.1 0.0038 17.2 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DUF1253 PF06862.7 KNZ79387.1 - 0.0091 14.4 0.1 0.067 11.5 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) DUF2608 PF11019.3 KNZ79387.1 - 0.014 14.3 0.1 0.027 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) ResIII PF04851.10 KNZ79387.1 - 0.049 13.4 0.0 0.37 10.5 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2529 PF10740.4 KNZ79387.1 - 0.063 12.7 0.2 0.58 9.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2529) PGM_PMM_I PF02878.11 KNZ79388.1 - 8.8e-27 93.2 0.0 1.5e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KNZ79388.1 - 9e-16 57.9 0.1 1.8e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KNZ79388.1 - 1.9e-15 57.0 0.0 6.6e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PHD PF00628.24 KNZ79388.1 - 1.9e-05 24.2 1.6 4.8e-05 22.9 1.1 1.6 1 0 0 1 1 1 1 PHD-finger PGM_PMM_IV PF00408.15 KNZ79388.1 - 0.00068 19.5 0.0 0.0023 17.8 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain BHD_3 PF10405.4 KNZ79388.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 3 PHD_2 PF13831.1 KNZ79388.1 - 0.8 9.0 2.4 0.59 9.4 0.4 1.8 2 0 0 2 2 2 0 PHD-finger Racemase_4 PF13615.1 KNZ79389.1 - 3.6e-16 59.2 0.4 6.2e-16 58.5 0.3 1.4 1 0 0 1 1 1 1 Putative alanine racemase MCM_bind PF09739.4 KNZ79389.1 - 3.4e-09 36.2 0.0 6.1e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor ATP-synt_F PF01990.12 KNZ79389.1 - 0.048 14.0 0.1 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit CDC50 PF03381.10 KNZ79390.1 - 1.3e-89 300.0 0.0 1.7e-89 299.6 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Fve PF09259.6 KNZ79390.1 - 0.026 14.4 0.1 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 Fungal immunomodulatory protein Fve RTC PF01137.16 KNZ79391.1 - 4.3e-67 225.2 0.0 5e-67 225.0 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KNZ79391.1 - 1.1e-21 76.7 0.4 2.4e-21 75.6 0.2 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain HOOK PF05622.7 KNZ79392.1 - 1.3e-53 181.8 23.3 1.3e-53 181.8 16.1 3.8 2 1 1 3 3 3 2 HOOK protein NYD-SP28_assoc PF14775.1 KNZ79392.1 - 0.0027 17.3 1.4 0.0027 17.3 1.0 6.1 6 0 0 6 6 6 2 Sperm tail C-terminal domain bZIP_1 PF00170.16 KNZ79392.1 - 0.004 17.0 1.6 0.004 17.0 1.1 9.1 7 2 3 10 10 10 2 bZIP transcription factor Surfac_D-trimer PF09006.6 KNZ79392.1 - 6.3 6.6 10.9 25 4.7 0.0 5.6 6 0 0 6 6 6 0 Lung surfactant protein D coiled-coil trimerisation DUF3972 PF13118.1 KNZ79393.1 - 0.081 13.0 11.4 0.097 12.7 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) ADIP PF11559.3 KNZ79393.1 - 0.89 9.4 23.0 0.3 10.9 1.4 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 KNZ79393.1 - 1.4 8.7 22.2 4.2 7.1 7.5 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 KNZ79393.1 - 4.3 7.4 17.1 2 8.5 1.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.7 KNZ79393.1 - 9.4 6.3 11.1 1.6 8.7 0.6 3.9 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat ESCRT-II PF05871.7 KNZ79394.1 - 1.8e-33 115.3 0.2 2.3e-33 115.0 0.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Glyco_hydro_35 PF01301.14 KNZ79395.1 - 1.4e-67 228.3 1.1 2.4e-67 227.5 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KNZ79395.1 - 1.2e-36 125.7 1.4 7.7e-34 116.6 0.9 2.5 1 1 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KNZ79395.1 - 4e-36 123.6 10.0 5e-20 71.8 0.0 3.3 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KNZ79395.1 - 3.3e-13 48.8 0.0 1e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 KNZ79395.1 - 0.005 16.0 0.3 0.021 14.0 0.0 2.0 1 1 1 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF1412 PF07203.6 KNZ79395.1 - 0.098 12.5 1.0 1.1 9.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1412) TMF_DNA_bd PF12329.3 KNZ79397.1 - 0.35 10.7 6.4 0.65 9.8 4.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Methyltransf_2 PF00891.13 KNZ79398.1 - 6.8e-19 68.0 0.0 8.9e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Ribosomal_L7Ae PF01248.21 KNZ79399.1 - 6.4e-25 86.4 0.1 8.3e-25 86.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KNZ79399.1 - 0.00012 21.9 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 KNZ79399.1 - 0.039 13.7 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Adenosine_kin PF04008.9 KNZ79399.1 - 0.079 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Adenosine specific kinase peroxidase PF00141.18 KNZ79400.1 - 1.2e-25 90.3 0.1 2.7e-25 89.2 0.1 1.5 1 0 0 1 1 1 1 Peroxidase VIT PF08487.5 KNZ79400.1 - 0.078 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain zf-DHHC PF01529.15 KNZ79401.1 - 2.5e-36 124.6 0.4 5e-36 123.6 0.1 1.7 1 1 0 1 1 1 1 DHHC palmitoyltransferase Fungal_trans PF04082.13 KNZ79402.1 - 1.6e-28 99.3 0.0 2.7e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Syja_N PF02383.13 KNZ79403.1 - 1.8e-84 283.2 0.0 2.6e-84 282.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KNZ79403.1 - 9e-22 76.6 0.0 1.6e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase UQ_con PF00179.21 KNZ79404.1 - 3e-49 166.0 0.0 3.4e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KNZ79404.1 - 0.0071 16.0 0.0 0.0083 15.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KNZ79404.1 - 0.049 13.5 1.2 0.11 12.4 0.8 1.8 1 1 0 1 1 1 0 RWD domain gag-asp_proteas PF13975.1 KNZ79405.1 - 0.0081 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1713 PF08213.6 KNZ79406.1 - 0.00027 20.4 10.4 0.00049 19.6 7.2 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Macoilin PF09726.4 KNZ79406.1 - 0.00075 17.9 4.0 0.00096 17.5 2.8 1.0 1 0 0 1 1 1 1 Transmembrane protein Clp1 PF06807.9 KNZ79407.1 - 9e-20 71.2 0.0 6.8e-19 68.3 0.0 1.9 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KNZ79407.1 - 2.9e-07 30.2 0.0 1.1e-06 28.3 0.0 2.0 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KNZ79407.1 - 0.0028 17.2 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 KNZ79407.1 - 0.081 12.6 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 KNZ79407.1 - 0.086 13.6 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 KNZ79408.1 - 3.2e-31 108.3 46.4 1.9e-28 99.2 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.1 KNZ79408.1 - 0.0032 16.8 7.4 0.73 9.2 1.7 3.1 2 1 1 3 3 3 3 Domain of unknown function (DUF4131) AAA PF00004.24 KNZ79409.1 - 1.4e-14 54.4 0.0 4.5e-14 52.7 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KNZ79409.1 - 3.4e-07 29.3 0.1 0.00021 20.0 0.0 2.8 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 KNZ79409.1 - 6.3e-06 25.3 0.0 1.8e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KNZ79409.1 - 0.00011 21.8 0.0 0.00033 20.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KNZ79409.1 - 0.00011 22.3 0.0 0.0025 17.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KNZ79409.1 - 0.00015 21.6 0.0 0.00038 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ79409.1 - 0.00024 21.8 0.2 0.00076 20.2 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KNZ79409.1 - 0.00096 19.1 0.0 0.039 13.9 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KNZ79409.1 - 0.0014 18.0 0.2 0.21 10.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 KNZ79409.1 - 0.0025 17.5 0.0 0.0065 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KNZ79409.1 - 0.0027 17.5 0.0 0.0072 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KNZ79409.1 - 0.0064 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 KNZ79409.1 - 0.011 15.4 0.1 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 KNZ79409.1 - 0.014 15.6 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KNZ79409.1 - 0.018 14.4 0.1 0.043 13.2 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein DNA_pol3_delta PF06144.8 KNZ79409.1 - 0.065 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF258 PF03193.11 KNZ79409.1 - 0.066 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KNZ79409.1 - 0.081 12.6 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 NTPase TIP49 PF06068.8 KNZ79409.1 - 0.082 11.6 0.0 0.2 10.3 0.0 1.6 1 0 0 1 1 1 0 TIP49 C-terminus DUF3835 PF12927.2 KNZ79410.1 - 2.8e-11 44.1 0.8 2.8e-11 44.1 0.5 5.8 4 2 1 5 5 5 2 Domain of unknown function (DUF3835) Salt_tol_Pase PF09506.5 KNZ79410.1 - 0.02 13.4 0.6 0.037 12.5 0.4 1.4 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Pkinase PF00069.20 KNZ79411.1 - 3e-52 177.3 0.0 5.2e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79411.1 - 3.2e-45 154.2 0.0 4.6e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.22 KNZ79411.1 - 0.068 12.6 0.1 0.19 11.2 0.1 1.8 1 0 0 1 1 1 0 SAP domain UbiA PF01040.13 KNZ79413.1 - 5e-30 104.5 21.0 6e-30 104.3 14.5 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family UBN2_2 PF14227.1 KNZ79414.1 - 0.046 13.2 0.1 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF128 PF01995.11 KNZ79414.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF128 DUF4267 PF14087.1 KNZ79415.1 - 0.027 14.0 4.1 2.2 7.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4267) RNase_H PF00075.19 KNZ79417.1 - 1.1e-05 25.7 0.0 7.5e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 RNase H KNTase_C PF07827.6 KNZ79418.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 KNTase C-terminal domain zf-CCHC_4 PF14392.1 KNZ79419.1 - 2 8.1 8.7 0.22 11.2 1.6 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 KNZ79419.1 - 8.7 6.1 13.3 3.9 7.3 0.9 2.7 1 1 1 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 KNZ79420.1 - 0.007 15.7 0.1 0.0073 15.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helitron_like_N PF14214.1 KNZ79422.1 - 1.7e-15 57.2 0.0 3e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus NAD_binding_4 PF07993.7 KNZ79425.1 - 3.3e-34 117.9 0.0 4.8e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KNZ79425.1 - 2.9e-15 55.6 0.1 1.2e-14 53.5 0.1 1.8 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KNZ79425.1 - 2.6e-05 23.7 0.0 5.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KNZ79425.1 - 0.0007 19.8 0.0 0.0021 18.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 KNZ79425.1 - 0.0031 17.5 0.1 0.14 12.1 0.0 2.6 2 1 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KNZ79425.1 - 0.0072 16.2 0.0 0.034 14.0 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KNZ79425.1 - 0.016 14.8 0.0 0.048 13.3 0.0 1.8 1 1 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 KNZ79425.1 - 0.021 13.5 0.0 0.037 12.7 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CFEM PF05730.6 KNZ79427.1 - 6.8e-12 45.0 14.1 1.5e-11 43.9 9.8 1.5 1 0 0 1 1 1 1 CFEM domain CBM_6 PF03422.10 KNZ79427.1 - 2.1 8.5 5.8 3.6 7.7 4.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) DUF1247 PF06851.6 KNZ79428.1 - 0.072 12.7 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1247) LysM PF01476.15 KNZ79430.1 - 1.7e-31 107.8 2.0 2.9e-07 30.2 0.0 6.4 6 0 0 6 6 6 6 LysM domain WEMBL PF05701.6 KNZ79435.1 - 5.3e-05 21.8 7.0 6.2e-05 21.6 4.9 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light APG6 PF04111.7 KNZ79435.1 - 0.0029 16.6 5.5 0.0044 16.1 3.8 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 Borrelia_P83 PF05262.6 KNZ79435.1 - 0.0086 14.3 6.2 0.0098 14.2 4.3 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein RmuC PF02646.11 KNZ79435.1 - 0.021 13.6 0.7 0.021 13.6 0.5 1.8 1 1 1 2 2 2 0 RmuC family AAA_27 PF13514.1 KNZ79435.1 - 0.035 11.7 11.1 0.041 11.5 7.7 1.0 1 0 0 1 1 1 0 AAA domain DUF4463 PF14703.1 KNZ79435.1 - 0.037 14.5 2.5 0.091 13.2 1.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) Lipoprotein_6 PF01441.14 KNZ79435.1 - 0.041 13.7 0.6 0.05 13.4 0.4 1.2 1 0 0 1 1 1 0 Lipoprotein DUF4398 PF14346.1 KNZ79435.1 - 0.043 13.8 3.1 0.063 13.3 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DUF3584 PF12128.3 KNZ79435.1 - 0.045 11.1 8.4 0.05 10.9 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SNARE PF05739.14 KNZ79435.1 - 0.049 13.3 1.5 6.1 6.6 0.6 2.4 1 1 1 2 2 2 0 SNARE domain DUF4407 PF14362.1 KNZ79435.1 - 0.14 11.0 4.4 0.17 10.8 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.14 KNZ79435.1 - 0.23 9.2 0.6 0.27 9.0 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 KNZ79435.1 - 0.34 10.5 8.8 0.52 9.9 6.1 1.4 1 1 0 1 1 1 0 Mnd1 family DASH_Spc19 PF08287.6 KNZ79435.1 - 0.46 10.0 6.9 0.58 9.7 4.8 1.3 1 0 0 1 1 1 0 Spc19 Atg14 PF10186.4 KNZ79435.1 - 0.53 9.1 4.5 0.61 8.9 3.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Cep57_CLD_2 PF14197.1 KNZ79435.1 - 1.3 9.0 11.8 0.29 11.0 3.6 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Pox_A_type_inc PF04508.7 KNZ79435.1 - 1.4 8.9 11.6 25 4.9 0.1 4.1 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat MutS_IV PF05190.13 KNZ79435.1 - 1.8 8.8 5.1 1.5 9.0 1.4 2.3 2 1 1 3 3 3 0 MutS family domain IV COG2 PF06148.6 KNZ79435.1 - 1.8 8.4 4.7 3.7 7.4 3.2 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 KNZ79435.1 - 1.9 8.2 9.2 6.2 6.5 6.3 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4337 PF14235.1 KNZ79435.1 - 2.4 7.9 4.4 3.2 7.5 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) CHD5 PF04420.9 KNZ79435.1 - 4.8 6.8 5.2 16 5.1 3.6 1.8 1 1 0 1 1 1 0 CHD5-like protein 4HB_MCP_1 PF12729.2 KNZ79436.1 - 0.0046 16.3 0.0 0.0097 15.2 0.0 1.5 1 1 1 2 2 2 1 Four helix bundle sensory module for signal transduction Prefoldin_3 PF13758.1 KNZ79436.1 - 0.019 14.6 1.7 0.16 11.7 0.2 2.3 2 1 0 2 2 2 0 Prefoldin subunit Lip_prot_lig_C PF10437.4 KNZ79436.1 - 0.024 14.2 0.5 0.083 12.5 0.1 2.0 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus WD40 PF00400.27 KNZ79438.1 - 5.2e-13 48.3 0.2 4.9e-10 38.8 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat F-box-like PF12937.2 KNZ79439.1 - 2.8e-09 36.5 1.2 9.4e-09 34.8 0.8 2.0 1 0 0 1 1 1 1 F-box-like adh_short PF00106.20 KNZ79440.1 - 9e-19 67.9 0.5 1e-12 48.2 0.1 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ79440.1 - 6.9e-15 55.4 0.8 4.3e-13 49.5 0.5 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ79440.1 - 7.4e-06 25.7 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KNZ79440.1 - 0.02 14.9 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F-box PF00646.28 KNZ79441.1 - 0.013 15.0 0.5 0.04 13.5 0.3 1.8 1 0 0 1 1 1 0 F-box domain Citrate_synt PF00285.16 KNZ79442.1 - 6.3e-18 64.6 0.0 4.7e-16 58.4 0.0 2.6 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 KNZ79442.1 - 1.2e-14 54.2 0.0 2.7e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 KNZ79442.1 - 4.5e-13 49.5 0.0 1.2e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 KNZ79442.1 - 5e-09 35.8 0.0 8.9e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 KNZ79442.1 - 4.4e-05 23.1 0.0 0.00012 21.6 0.0 1.8 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain Glyco_hydro_88 PF07470.8 KNZ79443.1 - 1.4e-12 47.3 0.1 2.7e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 FmdA_AmdA PF03069.10 KNZ79444.1 - 5.2e-73 245.8 0.0 1.2e-50 172.2 0.0 2.0 2 0 0 2 2 2 2 Acetamidase/Formamidase family AdoMet_MTase PF07757.8 KNZ79446.1 - 9.5e-33 112.6 0.2 2.3e-31 108.2 0.1 2.3 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 KNZ79446.1 - 0.0021 17.7 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KNZ79446.1 - 0.099 12.3 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KNZ79446.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF327 PF03885.8 KNZ79448.1 - 0.036 13.8 0.1 4.6 7.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF327) DUF1275 PF06912.6 KNZ79449.1 - 4.3e-22 78.3 10.3 5.7e-22 77.9 7.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2231 PF09990.4 KNZ79449.1 - 0.013 15.8 1.4 0.028 14.7 0.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) Rad60-SLD_2 PF13881.1 KNZ79450.1 - 1.9e-16 59.9 0.0 3.2e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KNZ79450.1 - 8.6e-05 21.8 0.0 0.0013 18.0 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KNZ79450.1 - 0.014 15.5 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain RTA1 PF04479.8 KNZ79451.1 - 1.9e-43 148.5 3.1 2.8e-43 147.9 2.1 1.2 1 0 0 1 1 1 1 RTA1 like protein Ribosomal_L38e PF01781.13 KNZ79453.1 - 1.4e-23 82.4 0.3 1.6e-23 82.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Hydrolase PF00702.21 KNZ79454.1 - 5.9e-23 82.3 0.0 1.6e-22 80.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KNZ79454.1 - 4.8e-22 78.1 0.6 5.3e-21 74.7 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 KNZ79454.1 - 3.5e-21 76.2 0.0 7e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KNZ79454.1 - 7.1e-06 25.8 0.0 1.9e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KNZ79454.1 - 0.074 12.6 0.0 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pyr_redox PF00070.22 KNZ79455.1 - 5e-11 42.8 0.2 9.6e-10 38.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KNZ79455.1 - 1.3e-09 38.2 0.1 0.00042 20.2 0.1 4.2 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNZ79455.1 - 0.052 13.5 1.3 12 5.9 0.0 2.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3533 PF12051.3 KNZ79456.1 - 1.5e-92 310.3 14.4 1.7e-92 310.1 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) F-box-like PF12937.2 KNZ79457.1 - 0.00017 21.2 0.4 0.00043 19.9 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ79457.1 - 0.0045 16.6 0.1 0.016 14.8 0.1 2.0 1 0 0 1 1 1 1 F-box domain DIOX_N PF14226.1 KNZ79458.1 - 1.9e-18 67.0 0.0 3.7e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KNZ79458.1 - 1.5e-11 44.4 0.0 4.4e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FYTT PF07078.6 KNZ79458.1 - 0.094 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Forty-two-three protein Fungal_trans PF04082.13 KNZ79459.1 - 5.2e-18 64.8 0.1 1.1e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ79459.1 - 0.00025 20.8 14.9 0.00045 20.0 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GPI-anchored PF10342.4 KNZ79460.1 - 7e-06 26.4 0.0 9.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KNZ79460.1 - 0.02 14.3 0.1 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) T_cell_tran_alt PF15128.1 KNZ79460.1 - 0.023 14.1 0.1 0.047 13.1 0.0 1.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered GLTP PF08718.6 KNZ79461.1 - 5.3e-36 123.8 0.0 6.5e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF342 PF03961.8 KNZ79463.1 - 0.021 13.2 2.5 0.034 12.5 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1644 PF07800.7 KNZ79463.1 - 0.064 13.1 1.7 5.7 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) FH2 PF02181.18 KNZ79463.1 - 0.08 11.8 8.1 0.015 14.1 2.7 1.8 2 0 0 2 2 2 0 Formin Homology 2 Domain COG2 PF06148.6 KNZ79463.1 - 0.11 12.4 8.8 0.027 14.3 3.6 1.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.7 KNZ79463.1 - 0.14 12.4 0.1 18 5.6 0.0 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2407_C PF13373.1 KNZ79463.1 - 0.14 12.0 0.8 19 5.1 0.0 2.4 2 0 0 2 2 2 0 DUF2407 C-terminal domain Fib_alpha PF08702.5 KNZ79463.1 - 0.26 11.3 7.3 0.11 12.5 2.5 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DivIVA PF05103.8 KNZ79463.1 - 0.3 11.1 13.0 0.21 11.6 3.1 2.5 2 1 0 2 2 2 0 DivIVA protein DUF2203 PF09969.4 KNZ79463.1 - 0.36 11.0 7.9 1.3 9.3 2.2 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMF_TATA_bd PF12325.3 KNZ79463.1 - 0.46 10.2 19.5 0.46 10.2 5.8 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding SPX PF03105.14 KNZ79463.1 - 0.55 9.9 9.2 1.9 8.1 6.4 1.8 1 1 0 1 1 1 0 SPX domain FYDLN_acid PF09538.5 KNZ79463.1 - 1 9.9 6.4 0.6 10.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TMPIT PF07851.8 KNZ79463.1 - 1.2 8.1 4.6 0.44 9.5 0.9 1.8 2 0 0 2 2 2 0 TMPIT-like protein DUF4363 PF14276.1 KNZ79463.1 - 1.7 8.3 4.9 0.46 10.1 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Cep57_MT_bd PF06657.8 KNZ79463.1 - 2.2 8.2 9.7 0.42 10.5 1.9 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Mnd1 PF03962.10 KNZ79463.1 - 3 7.4 13.6 3 7.4 4.3 2.3 2 0 0 2 2 2 0 Mnd1 family IncA PF04156.9 KNZ79463.1 - 3.4 7.2 17.7 0.035 13.7 5.8 2.2 2 1 0 2 2 2 0 IncA protein Phage_GPO PF05929.6 KNZ79463.1 - 4 6.6 8.6 1.7 7.8 1.4 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2730 PF10805.3 KNZ79463.1 - 6.5 6.5 8.2 4.3 7.1 1.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF1664 PF07889.7 KNZ79463.1 - 8.5 6.1 8.1 3.7 7.3 2.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2207 PF09972.4 KNZ79464.1 - 1.2 7.6 6.2 0.21 10.1 1.1 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF1129 PF06570.6 KNZ79464.1 - 2.1 7.6 4.2 7.9 5.7 0.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) NPV_P10 PF05531.7 KNZ79465.1 - 9 6.6 14.0 27 5.0 0.0 5.6 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein RNase_H PF00075.19 KNZ79466.1 - 1.2e-05 25.7 0.1 2.9e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 RNase H Pkinase PF00069.20 KNZ79467.1 - 0.037 13.1 0.0 0.037 13.1 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain Sec10 PF07393.6 KNZ79468.1 - 3.1e-113 379.3 0.0 1.3e-112 377.2 0.0 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec10 RdRP_5 PF07925.6 KNZ79468.1 - 0.01 13.2 0.5 0.016 12.6 0.4 1.2 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 Pkinase PF00069.20 KNZ79470.1 - 6.5e-05 22.2 0.1 0.0025 17.0 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Innate_immun PF12782.2 KNZ79471.1 - 2.3 7.3 5.3 0.68 9.1 0.6 2.1 2 1 0 2 2 2 0 Invertebrate innate immunity transcript family GLTP PF08718.6 KNZ79474.1 - 8.1e-28 97.3 0.0 9.4e-28 97.1 0.0 1.0 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF4123 PF13503.1 KNZ79474.1 - 0.033 14.1 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) DUF4626 PF15422.1 KNZ79474.1 - 0.036 14.0 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4626) p450 PF00067.17 KNZ79475.1 - 1.6e-15 56.6 0.0 1.7e-14 53.2 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Cys_Met_Meta_PP PF01053.15 KNZ79477.1 - 4.7e-134 446.4 0.0 5.8e-134 446.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KNZ79477.1 - 5e-11 42.2 0.1 5.4e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KNZ79477.1 - 1.1e-07 31.2 0.0 2.2e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KNZ79477.1 - 4.3e-07 29.2 0.0 6.9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KNZ79477.1 - 1.3e-06 27.4 0.1 2.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 KNZ79477.1 - 0.015 13.6 0.0 0.027 12.7 0.0 1.3 1 0 0 1 1 1 0 Methionine gamma-lyase GDC-P PF02347.11 KNZ79477.1 - 0.035 12.7 0.0 0.055 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.15 KNZ79478.1 - 1.3e-34 119.0 0.0 1.3e-33 115.8 0.0 1.9 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_3 PF00933.16 KNZ79480.1 - 1e-80 270.9 0.0 1.5e-80 270.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KNZ79480.1 - 1.8e-47 161.7 0.0 2.6e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KNZ79480.1 - 3e-07 30.2 0.0 5.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.16 KNZ79481.1 - 8.3e-73 244.9 0.0 1.2e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KNZ79481.1 - 6.4e-42 143.6 0.0 1.3e-41 142.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KNZ79481.1 - 2.3e-18 65.9 0.0 4.6e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Zip PF02535.17 KNZ79482.1 - 1.5e-53 181.8 5.5 1.7e-53 181.6 3.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF566 PF04484.7 KNZ79483.1 - 0.36 10.3 8.3 0.48 9.8 5.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Zip PF02535.17 KNZ79484.1 - 3e-49 167.7 6.6 4.5e-49 167.1 4.6 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Adeno_E3B PF03376.9 KNZ79484.1 - 0.049 13.5 0.1 7.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Adenovirus E3B protein Aldedh PF00171.17 KNZ79485.1 - 2.1e-16 59.3 0.1 2.7e-16 58.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NAD_binding_10 PF13460.1 KNZ79490.1 - 7.3e-09 35.8 0.0 0.0056 16.6 0.0 2.7 2 1 0 2 2 2 2 NADH(P)-binding adh_short PF00106.20 KNZ79490.1 - 0.053 13.4 0.1 0.092 12.6 0.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase ApbA PF02558.11 KNZ79490.1 - 0.055 12.9 0.0 0.088 12.2 0.0 1.4 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.8 KNZ79490.1 - 0.079 12.2 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family p450 PF00067.17 KNZ79491.1 - 3.2e-49 167.7 0.0 2.8e-48 164.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KNZ79492.1 - 3.7e-47 160.9 0.0 5.8e-46 156.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 KNZ79493.1 - 1e-21 77.1 14.3 8.7e-21 74.0 9.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ79493.1 - 6.1e-14 51.5 13.6 1.6e-09 36.9 4.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PrgI PF12666.2 KNZ79493.1 - 1.2 9.3 11.7 4.7 7.4 0.3 3.6 3 0 0 3 3 3 0 PrgI family protein Phage_integrase PF00589.17 KNZ79495.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family HNH_2 PF13391.1 KNZ79496.1 - 0.00063 19.4 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease RVT_1 PF00078.22 KNZ79497.1 - 0.016 14.5 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Terpene_synth_C PF03936.11 KNZ79499.1 - 5.8e-15 55.2 0.1 8e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain APG12 PF04110.8 KNZ79500.1 - 9.1e-31 105.9 0.0 1.1e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 KNZ79500.1 - 0.0014 18.5 0.0 0.0017 18.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like GAD-like PF08887.6 KNZ79500.1 - 0.073 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 GAD-like domain Terpene_synth_C PF03936.11 KNZ79502.1 - 3e-15 56.1 0.2 4e-15 55.7 0.2 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF4259 PF14078.1 KNZ79502.1 - 0.11 13.0 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Sec23_helical PF04815.10 KNZ79504.1 - 0.028 13.8 0.2 0.035 13.5 0.1 1.3 1 1 0 1 1 1 0 Sec23/Sec24 helical domain Acyl-CoA_dh_1 PF00441.19 KNZ79505.1 - 5.6e-20 71.9 0.9 9.8e-20 71.1 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KNZ79505.1 - 5e-07 29.1 0.3 1.2e-06 27.9 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KNZ79505.1 - 5.3e-05 23.4 0.1 0.00017 21.8 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain 4HBT PF03061.17 KNZ79506.1 - 5.1e-11 42.5 0.1 7e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KNZ79506.1 - 0.015 15.0 0.1 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily Alg6_Alg8 PF03155.10 KNZ79507.1 - 6.7e-137 457.1 24.2 8.2e-137 456.8 16.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Thaumatin PF00314.12 KNZ79508.1 - 1.8e-58 197.4 13.3 2.2e-58 197.2 9.2 1.0 1 0 0 1 1 1 1 Thaumatin family Chol_subst-bind PF09129.6 KNZ79509.1 - 0.027 13.6 0.2 0.034 13.2 0.1 1.1 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding APH PF01636.18 KNZ79513.1 - 3.5e-07 30.1 0.1 5.4e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ79513.1 - 0.0077 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KNZ79513.1 - 0.012 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Thaumatin PF00314.12 KNZ79514.1 - 6.3e-58 195.7 12.6 6.9e-58 195.5 8.7 1.0 1 0 0 1 1 1 1 Thaumatin family Asparaginase_II PF06089.7 KNZ79514.1 - 0.1 11.2 2.0 0.14 10.8 1.4 1.1 1 0 0 1 1 1 0 L-asparaginase II Lactonase PF10282.4 KNZ79516.1 - 2.3e-36 125.5 0.0 2.8e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.1 KNZ79516.1 - 0.027 14.7 0.7 3.8 7.9 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain Catalase PF00199.14 KNZ79517.1 - 8.3e-184 610.6 0.5 1.1e-183 610.2 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KNZ79517.1 - 2.3e-15 56.2 0.1 2.3e-15 56.2 0.1 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive EABR PF12180.3 KNZ79517.1 - 0.076 12.3 0.0 0.21 10.9 0.0 1.7 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 HMG_box PF00505.14 KNZ79518.1 - 0.0039 17.4 0.7 1.8 8.8 0.0 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box rRNA_proc-arch PF13234.1 KNZ79519.1 - 3.1e-95 318.3 0.0 4.8e-95 317.7 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KNZ79519.1 - 8.9e-61 204.2 0.8 1.9e-60 203.1 0.6 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KNZ79519.1 - 3e-21 75.6 0.1 1.3e-20 73.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ79519.1 - 1.4e-07 31.2 0.0 4.1e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain T2SE PF00437.15 KNZ79519.1 - 0.0051 15.7 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 KNZ79519.1 - 0.061 13.1 0.0 0.9 9.3 0.0 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KNZ79519.1 - 0.13 12.3 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KNZ79519.1 - 0.17 11.6 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Glyco_hydro_18 PF00704.23 KNZ79520.1 - 9e-93 311.4 9.9 9e-93 311.4 6.8 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.9 KNZ79520.1 - 5.3e-09 35.5 11.6 1.7e-08 33.9 8.1 2.0 1 0 0 1 1 1 1 Carbohydrate binding domain Ras PF00071.17 KNZ79521.1 - 1.4e-31 109.0 0.3 5.7e-31 107.0 0.2 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KNZ79521.1 - 2.9e-20 72.9 0.2 3.4e-19 69.4 0.0 2.3 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 KNZ79521.1 - 3.7e-07 29.5 0.1 6.5e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KNZ79521.1 - 4.7e-06 25.9 0.3 6.2e-06 25.5 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KNZ79521.1 - 0.0086 16.0 0.0 0.017 15.0 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.15 KNZ79521.1 - 0.032 12.9 3.4 0.069 11.8 0.0 2.3 2 1 1 3 3 3 0 G-protein alpha subunit DLIC PF05783.6 KNZ79521.1 - 0.087 11.4 0.1 7.4 5.1 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) CybS PF05328.7 KNZ79522.1 - 3.8e-46 156.0 0.1 4.8e-46 155.6 0.1 1.1 1 0 0 1 1 1 1 CybS Pkinase PF00069.20 KNZ79523.1 - 3.2e-71 239.5 0.0 4.2e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79523.1 - 4.3e-34 117.7 0.0 5.7e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KNZ79523.1 - 9.7e-12 45.2 2.1 2e-11 44.1 1.5 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KNZ79523.1 - 0.0021 17.0 0.0 0.004 16.1 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KNZ79523.1 - 0.019 14.6 0.3 0.05 13.3 0.1 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KNZ79523.1 - 0.097 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family polyprenyl_synt PF00348.12 KNZ79524.1 - 1.3e-56 191.3 0.0 2.5e-53 180.5 0.0 2.6 1 1 0 1 1 1 1 Polyprenyl synthetase GMC_oxred_N PF00732.14 KNZ79525.1 - 1.5e-16 60.4 0.0 7.8e-16 58.0 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ79525.1 - 2.5e-16 60.2 0.1 5.7e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KNZ79525.1 - 5.3e-09 35.4 0.0 9.1e-06 24.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ79525.1 - 1.7e-07 30.4 0.0 3e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KNZ79525.1 - 2e-05 24.4 0.6 5.4e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KNZ79525.1 - 5.9e-05 22.2 0.0 0.00087 18.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KNZ79525.1 - 0.00012 21.2 0.1 0.00022 20.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KNZ79525.1 - 0.00016 20.2 0.0 0.00025 19.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KNZ79525.1 - 0.0013 18.7 0.1 0.01 15.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KNZ79525.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KNZ79525.1 - 0.0066 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KNZ79525.1 - 0.098 11.5 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Mannosyl_trans2 PF04188.8 KNZ79526.1 - 3.5e-43 148.1 23.1 3.2e-39 135.1 14.4 2.0 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V)) Herpes_UL25 PF01499.11 KNZ79527.1 - 0.33 9.1 5.0 0.37 9.0 3.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family Phlebovirus_NSM PF07246.6 KNZ79527.1 - 0.63 9.1 7.0 0.78 8.8 4.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M PEARLI-4 PF05278.7 KNZ79527.1 - 1.6 7.9 10.4 1.5 8.1 6.5 1.4 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DDE_Tnp_1_6 PF13751.1 KNZ79527.1 - 4.4 7.3 7.4 15 5.6 5.2 1.7 1 1 0 1 1 1 0 Transposase DDE domain Borrelia_P83 PF05262.6 KNZ79527.1 - 8 4.6 11.1 9.6 4.3 7.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein RNase_H PF00075.19 KNZ79528.1 - 4.4e-10 40.0 0.1 8e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 RNase H F-box-like PF12937.2 KNZ79529.1 - 2.1e-06 27.3 2.7 1.5e-05 24.6 0.4 3.2 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 KNZ79531.1 - 0.007 16.0 0.1 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like bcl-2I13 PF12201.3 KNZ79532.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing F-box-like PF12937.2 KNZ79533.1 - 3.8e-09 36.1 0.2 1.4e-07 31.1 0.0 3.0 2 1 0 2 2 2 1 F-box-like EF-hand_1 PF00036.27 KNZ79536.1 - 1.2e-20 71.1 1.3 8.7e-06 24.6 0.1 4.8 4 0 0 4 4 4 4 EF hand Bromodomain PF00439.20 KNZ79536.1 - 7e-20 70.7 0.2 1.4e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 Bromodomain EF-hand_6 PF13405.1 KNZ79536.1 - 6e-18 63.0 0.7 2.7e-06 26.7 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 KNZ79536.1 - 2.7e-15 56.2 1.5 1.7e-07 31.2 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KNZ79536.1 - 2.1e-13 48.9 1.1 0.0075 15.5 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KNZ79536.1 - 4.2e-10 39.0 4.0 1.3e-05 24.7 0.0 4.1 3 1 1 4 4 4 2 EF-hand domain pair Bromo_TP PF07524.8 KNZ79536.1 - 0.00018 21.1 0.0 0.00034 20.2 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Sugar_tr PF00083.19 KNZ79538.1 - 7.4e-95 318.1 9.0 1.5e-94 317.1 6.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ79538.1 - 7.3e-27 94.0 26.1 5.5e-26 91.1 13.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KNZ79538.1 - 0.00074 17.8 0.7 0.0016 16.7 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 KNZ79538.1 - 0.0045 15.7 0.2 0.008 14.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_3 PF05977.8 KNZ79538.1 - 1.5 6.8 9.9 0.21 9.6 0.2 2.5 2 1 1 3 3 3 0 Transmembrane secretion effector FRD2 PF03197.8 KNZ79540.1 - 0.13 12.8 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage FRD2 protein DUF3529 PF12046.3 KNZ79544.1 - 0.34 9.9 3.5 0.12 11.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3529) WD40 PF00400.27 KNZ79545.1 - 7.8e-10 38.2 15.0 0.00031 20.5 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF3312 PF11768.3 KNZ79545.1 - 0.12 10.6 0.0 0.21 9.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DNA_pol_B PF00136.16 KNZ79546.1 - 2.3e-89 300.3 0.0 3.3e-89 299.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KNZ79546.1 - 4.3e-24 84.9 0.0 4.1e-13 48.9 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KNZ79546.1 - 5.5e-12 45.5 9.2 1e-11 44.6 6.4 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Aldose_epim PF01263.15 KNZ79548.1 - 1.7e-28 99.6 0.0 1.9e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase HEAT PF02985.17 KNZ79549.1 - 1.9e-39 130.1 16.5 0.00093 19.0 0.0 12.8 13 0 0 13 13 13 9 HEAT repeat HEAT_2 PF13646.1 KNZ79549.1 - 7.1e-31 106.3 10.7 8.3e-09 35.6 0.0 6.2 2 2 3 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 KNZ79549.1 - 7.2e-11 42.2 21.2 0.0062 16.9 0.0 9.5 7 2 3 10 10 10 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KNZ79549.1 - 2.4e-08 34.2 0.1 0.5 10.7 0.0 6.2 3 3 5 8 8 8 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 KNZ79549.1 - 4e-06 26.4 4.3 2.9 7.8 0.0 6.5 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 KNZ79549.1 - 0.023 15.1 3.1 3.1 8.5 0.1 4.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Cnd1 PF12717.2 KNZ79549.1 - 0.041 13.7 0.4 2.1 8.1 0.0 3.7 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 KNZ79549.1 - 1.1 9.2 5.0 20 5.2 0.4 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Ribosomal_S24e PF01282.14 KNZ79551.1 - 1e-34 118.1 0.0 1.6e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Actin PF00022.14 KNZ79552.1 - 3.7e-117 391.0 0.0 4.4e-117 390.8 0.0 1.0 1 0 0 1 1 1 1 Actin DEAD PF00270.24 KNZ79554.1 - 4.8e-39 133.5 0.0 5.9e-38 130.0 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Apc4 PF12896.2 KNZ79554.1 - 3.3e-35 121.2 0.3 7.8e-35 120.0 0.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Helicase_C PF00271.26 KNZ79554.1 - 4.9e-24 84.0 0.0 1.3e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain bZIP_1 PF00170.16 KNZ79554.1 - 0.00068 19.5 5.3 0.0021 17.9 3.7 1.9 1 0 0 1 1 1 1 bZIP transcription factor DUF904 PF06005.7 KNZ79554.1 - 0.011 16.0 1.5 0.031 14.5 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 KNZ79554.1 - 0.027 14.8 0.5 0.027 14.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) hNIFK_binding PF12196.3 KNZ79559.1 - 0.2 11.0 0.4 0.2 11.0 0.3 2.0 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK ACP53EA PF06313.6 KNZ79561.1 - 0.019 14.9 0.1 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Drosophila ACP53EA protein gag-asp_proteas PF13975.1 KNZ79562.1 - 0.15 11.8 0.1 0.99 9.2 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RasGEF PF00617.14 KNZ79563.1 - 4.9e-31 107.9 0.1 8.8e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KNZ79563.1 - 1.8e-08 34.3 0.0 5.1e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.17 KNZ79563.1 - 0.00011 21.6 0.1 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 1 Ras family Viral_helicase1 PF01443.13 KNZ79563.1 - 0.044 13.2 0.3 0.093 12.2 0.2 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Miro PF08477.8 KNZ79563.1 - 0.059 13.8 0.0 0.32 11.4 0.0 2.3 1 1 0 1 1 1 0 Miro-like protein SurE PF01975.12 KNZ79564.1 - 1.8e-33 115.5 0.0 1e-32 113.0 0.0 1.9 1 1 0 1 1 1 1 Survival protein SurE Glyco_hydro_16 PF00722.16 KNZ79565.1 - 2.1e-09 36.9 0.0 3.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ribosomal_L15e PF00827.12 KNZ79566.1 - 2.9e-79 265.0 13.1 2.6e-78 261.9 9.1 1.9 1 1 0 1 1 1 1 Ribosomal L15 Pex2_Pex12 PF04757.9 KNZ79568.1 - 1.1e-48 165.7 6.5 1.9e-48 164.8 4.5 1.4 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Ank_2 PF12796.2 KNZ79568.1 - 9.4e-35 118.8 1.0 5.2e-11 42.7 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) SPX PF03105.14 KNZ79568.1 - 4.7e-32 111.8 0.0 5e-29 101.9 0.0 2.2 1 1 0 1 1 1 1 SPX domain Ank PF00023.25 KNZ79568.1 - 3.5e-31 105.4 6.3 2.2e-06 27.1 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KNZ79568.1 - 4e-30 103.6 2.1 2.5e-11 43.7 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ79568.1 - 6.5e-22 75.4 3.3 3.4e-05 23.6 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KNZ79568.1 - 6.7e-18 64.3 8.4 4.3e-07 29.9 0.0 5.9 2 2 4 6 6 6 4 Ankyrin repeats (many copies) GDPD PF03009.12 KNZ79568.1 - 4.3e-10 39.5 0.0 8.7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Prok-RING_4 PF14447.1 KNZ79568.1 - 0.13 11.7 0.1 0.29 10.6 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4631 PF15450.1 KNZ79568.1 - 0.43 8.8 0.4 0.62 8.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) DUF336 PF03928.9 KNZ79569.1 - 0.025 14.3 0.0 0.069 12.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF336) SSB PF00436.20 KNZ79570.1 - 1.1e-15 57.3 0.0 1.5e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family GTP_EFTU PF00009.22 KNZ79571.1 - 2.7e-32 111.7 0.0 5.4e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KNZ79571.1 - 6.7e-08 32.5 0.2 1.5e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D4 PF14578.1 KNZ79571.1 - 2.2e-06 27.2 0.0 4.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D3 PF03143.12 KNZ79571.1 - 3.1e-05 24.0 0.0 8.6e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KNZ79571.1 - 0.0016 18.4 0.2 0.0042 17.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KNZ79571.1 - 0.031 14.2 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Na_Ca_ex PF01699.19 KNZ79572.1 - 3.5e-10 39.6 25.1 7.5e-05 22.3 3.8 3.4 2 1 1 3 3 3 3 Sodium/calcium exchanger protein AgrD PF05931.6 KNZ79572.1 - 0.04 13.5 0.2 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 Staphylococcal AgrD protein DUF962 PF06127.6 KNZ79572.1 - 0.51 10.2 4.6 14 5.6 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF962) Na_Ca_ex PF01699.19 KNZ79573.1 - 0.016 14.8 8.0 0.025 14.1 5.5 1.3 1 0 0 1 1 1 0 Sodium/calcium exchanger protein FA_desaturase PF00487.19 KNZ79573.1 - 0.5 9.7 3.7 0.65 9.3 2.6 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Acyltransferase PF01553.16 KNZ79574.1 - 1.1e-21 76.6 0.0 1.5e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase PIF1 PF05970.9 KNZ79576.1 - 1.3e-30 106.6 0.0 1.4e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Torsin PF06309.6 KNZ79576.1 - 0.032 14.1 0.1 0.052 13.4 0.1 1.3 1 0 0 1 1 1 0 Torsin Viral_helicase1 PF01443.13 KNZ79576.1 - 0.034 13.6 0.2 0.038 13.4 0.1 1.4 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2791 PF10923.3 KNZ79576.1 - 0.044 12.3 0.0 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) RNA_helicase PF00910.17 KNZ79576.1 - 0.064 13.4 0.1 0.17 12.1 0.1 1.8 1 1 0 1 1 1 0 RNA helicase AAA_31 PF13614.1 KNZ79576.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain Asp_protease_2 PF13650.1 KNZ79580.1 - 3.4e-07 30.6 0.0 5.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ79580.1 - 0.003 17.0 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KNZ79580.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Nucleoside_tran PF01733.13 KNZ79582.1 - 1.5e-35 122.8 13.9 1.5e-35 122.8 9.6 2.1 2 1 0 2 2 2 1 Nucleoside transporter RPN7 PF10602.4 KNZ79585.1 - 0.49 9.7 2.6 0.23 10.8 0.2 1.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Chromo PF00385.19 KNZ79586.1 - 0.00079 19.0 1.4 0.0011 18.5 1.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KNZ79586.1 - 0.012 15.3 2.7 0.012 15.2 0.1 2.0 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain MRC1 PF09444.5 KNZ79587.1 - 3.8e-13 49.9 21.3 3.8e-13 49.9 14.8 4.8 5 1 1 6 6 6 1 MRC1-like domain Ank_2 PF12796.2 KNZ79588.1 - 1.2e-20 73.6 0.5 5.5e-10 39.4 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ79588.1 - 1.5e-20 71.9 0.2 3.7e-09 35.9 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KNZ79588.1 - 2.3e-17 62.6 0.1 2.5e-07 30.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KNZ79588.1 - 3.2e-16 59.3 2.7 5.2e-10 39.5 0.0 4.8 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ79588.1 - 8.7e-16 56.4 1.5 7.7e-06 25.6 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.8 KNZ79588.1 - 0.00039 20.0 0.0 0.0039 16.7 0.0 2.5 1 1 0 1 1 1 1 KilA-N domain Acyl-CoA_dh_C PF12806.2 KNZ79588.1 - 0.031 14.1 0.4 0.64 9.8 0.0 2.6 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like DUF3122 PF11320.3 KNZ79588.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) Glyco_hydro_3_C PF01915.17 KNZ79589.1 - 6.6e-49 166.4 0.1 1.1e-48 165.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 KNZ79589.1 - 3.9e-20 72.0 0.0 6.2e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 KNZ79589.1 - 0.00019 21.3 0.0 0.00044 20.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DDR PF08841.5 KNZ79589.1 - 0.14 10.9 0.5 0.22 10.3 0.3 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain p450 PF00067.17 KNZ79591.1 - 1.7e-64 218.0 0.0 2.5e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.13 KNZ79592.1 - 8.2e-30 103.8 17.5 1.1e-29 103.4 12.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.17 KNZ79593.1 - 2.6e-17 62.5 0.0 2.8e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 An_peroxidase PF03098.10 KNZ79596.1 - 8.7e-76 255.3 0.0 1.3e-73 248.1 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase Longin PF13774.1 KNZ79597.1 - 1.6e-18 66.0 0.0 2.9e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KNZ79597.1 - 1.9e-14 52.9 0.7 3.2e-14 52.2 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 KNZ79597.1 - 0.015 15.0 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 MIS13 PF08202.6 KNZ79597.1 - 0.073 12.1 0.2 0.097 11.7 0.1 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Actin PF00022.14 KNZ79598.1 - 0.00019 19.9 0.0 0.0023 16.4 0.0 2.2 1 1 1 2 2 2 2 Actin Tetraspannin PF00335.15 KNZ79599.1 - 0.0032 16.7 11.7 0.0032 16.7 8.1 2.0 1 1 1 2 2 2 1 Tetraspanin family DUF2759 PF10958.3 KNZ79599.1 - 0.037 13.6 2.5 4.1 7.0 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) TMEM213 PF15192.1 KNZ79599.1 - 0.043 13.8 0.1 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 TMEM213 family ABC2_membrane_4 PF12730.2 KNZ79599.1 - 0.26 10.4 23.1 0.023 13.8 12.2 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF1211 PF06736.6 KNZ79599.1 - 1.6 8.8 5.5 1.4 9.1 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1211) Mannosyl_trans2 PF04188.8 KNZ79600.1 - 1.3e-10 40.7 4.6 2e-05 23.7 1.4 2.1 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V)) RVT_1 PF00078.22 KNZ79600.1 - 0.0094 15.3 0.0 0.026 13.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pox_P21 PF05313.7 KNZ79602.1 - 0.00012 21.3 3.8 0.0002 20.6 2.6 1.4 1 0 0 1 1 1 1 Poxvirus P21 membrane protein Rapsyn_N PF10579.4 KNZ79602.1 - 0.15 11.8 0.3 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TSA PF03249.8 KNZ79604.1 - 0.016 13.7 4.7 0.018 13.5 3.3 1.0 1 0 0 1 1 1 0 Type specific antigen ING PF12998.2 KNZ79604.1 - 0.036 14.3 3.4 0.08 13.2 2.3 1.7 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Chalcone PF02431.10 KNZ79604.1 - 0.04 13.2 0.5 0.058 12.7 0.3 1.3 1 1 0 1 1 1 0 Chalcone-flavanone isomerase DUF1712 PF08217.6 KNZ79607.1 - 1.2e-16 60.1 0.0 1.6e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) zf-CCCH PF00642.19 KNZ79608.1 - 4.8e-11 42.0 22.8 9.8e-06 25.1 1.0 5.2 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Usp PF00582.21 KNZ79608.1 - 0.081 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Universal stress protein family zf-C3H1 PF10650.4 KNZ79608.1 - 1.1 8.7 6.2 33 4.0 0.4 3.8 3 0 0 3 3 3 0 Putative zinc-finger domain Nucleoplasmin PF03066.10 KNZ79608.1 - 4.4 6.8 11.1 7.7 6.0 7.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin DnaJ-X PF14308.1 KNZ79609.1 - 5.3e-51 172.7 0.0 5.3e-51 172.7 0.0 2.3 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 KNZ79609.1 - 1.6e-07 30.9 3.1 1.6e-07 30.9 0.1 2.5 2 0 0 2 2 2 1 DnaJ domain DUF4653 PF15546.1 KNZ79609.1 - 0.24 10.6 7.4 0.014 14.7 1.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) Metal_resist PF13801.1 KNZ79609.1 - 7.7 6.5 15.6 3.2 7.7 0.5 3.4 3 0 0 3 3 3 0 Heavy-metal resistance Mif2_N PF15624.1 KNZ79610.1 - 6.3 7.3 11.7 0.34 11.4 3.5 1.9 1 1 1 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal PIF1 PF05970.9 KNZ79614.1 - 3.5e-52 177.5 0.1 1.1e-47 162.7 0.2 2.1 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KNZ79614.1 - 4.4e-15 55.7 0.0 1.8e-14 53.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KNZ79614.1 - 5.4e-08 33.0 0.0 9.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNZ79614.1 - 0.00025 20.7 0.5 0.0006 19.5 0.4 1.7 1 1 1 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 KNZ79614.1 - 0.00036 19.6 0.9 0.014 14.4 0.1 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 KNZ79614.1 - 0.0011 18.6 0.5 0.093 12.4 0.3 2.4 1 1 0 1 1 1 1 NTPase AAA_16 PF13191.1 KNZ79614.1 - 0.0018 18.2 0.1 0.01 15.8 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 KNZ79614.1 - 0.0019 17.3 0.1 0.0043 16.2 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KNZ79614.1 - 0.0023 17.1 0.0 0.0049 16.1 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.24 KNZ79614.1 - 0.0036 17.5 0.1 0.0066 16.6 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KNZ79614.1 - 0.0057 16.5 0.0 0.017 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 KNZ79614.1 - 0.0073 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_5 PF07728.9 KNZ79614.1 - 0.01 15.5 0.7 0.064 12.9 0.2 2.5 2 2 1 3 3 3 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 KNZ79614.1 - 0.022 13.3 0.1 0.036 12.6 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 KNZ79614.1 - 0.024 14.2 0.1 0.052 13.2 0.1 1.5 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 KNZ79614.1 - 0.039 13.6 0.4 0.13 11.9 0.3 1.8 1 1 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 KNZ79614.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 KNZ79614.1 - 0.044 13.9 1.6 0.44 10.7 0.0 2.9 3 1 0 3 3 3 0 RNA helicase Viral_helicase1 PF01443.13 KNZ79614.1 - 0.082 12.4 3.7 0.16 11.4 0.6 2.8 2 1 0 2 2 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 KNZ79614.1 - 0.089 12.3 0.1 16 5.0 0.0 2.7 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 KNZ79614.1 - 0.13 12.5 0.2 0.43 10.8 0.1 1.8 1 1 0 1 1 1 0 ABC transporter MobB PF03205.9 KNZ79614.1 - 0.16 11.7 0.4 0.27 10.9 0.3 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RhoGAP PF00620.22 KNZ79615.1 - 1.3e-40 138.5 0.5 3.9e-40 136.9 0.0 2.0 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.18 KNZ79615.1 - 2.4e-08 34.0 2.1 1.1e-07 31.8 0.1 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF1708 PF08101.6 KNZ79615.1 - 0.027 13.3 0.0 0.064 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) RGS PF00615.14 KNZ79615.1 - 0.28 11.2 3.9 2.3 8.3 2.0 2.7 2 1 0 2 2 2 0 Regulator of G protein signaling domain ABC_membrane PF00664.18 KNZ79616.1 - 1.1e-46 159.4 26.2 4.3e-25 88.6 2.5 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 KNZ79616.1 - 3.7e-46 156.8 0.0 5e-27 94.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KNZ79616.1 - 4.3e-11 42.4 5.1 0.004 16.4 0.0 4.1 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KNZ79616.1 - 2.3e-10 40.9 3.5 0.016 15.1 0.2 4.3 2 2 1 3 3 3 3 AAA domain AAA_23 PF13476.1 KNZ79616.1 - 3.1e-07 30.9 0.3 0.00036 20.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KNZ79616.1 - 6.1e-07 29.0 0.0 0.0093 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KNZ79616.1 - 2.6e-06 26.8 0.0 0.023 14.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KNZ79616.1 - 7e-06 26.1 0.0 0.17 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 KNZ79616.1 - 2.6e-05 23.2 0.0 0.013 14.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.12 KNZ79616.1 - 8.3e-05 22.5 0.1 0.021 14.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 KNZ79616.1 - 8.6e-05 22.0 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 KNZ79616.1 - 0.00012 21.8 0.1 0.34 10.6 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KNZ79616.1 - 0.0002 21.8 0.0 0.72 10.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 KNZ79616.1 - 0.00033 20.7 0.1 0.16 12.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 KNZ79616.1 - 0.00089 19.2 0.3 1 9.3 0.1 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KNZ79616.1 - 0.00098 19.9 0.0 2 9.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KNZ79616.1 - 0.00099 18.3 0.0 0.4 9.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KNZ79616.1 - 0.0014 18.3 0.1 0.038 13.6 0.0 2.6 2 1 0 2 2 2 1 Archaeal ATPase Adeno_IVa2 PF02456.10 KNZ79616.1 - 0.0034 16.1 0.2 0.047 12.3 0.0 2.5 3 0 0 3 3 3 1 Adenovirus IVa2 protein AAA_10 PF12846.2 KNZ79616.1 - 0.004 16.6 0.1 2.1 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 KNZ79616.1 - 0.0053 17.0 0.0 3 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KNZ79616.1 - 0.0082 15.8 0.8 7.1 6.3 0.0 3.7 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 KNZ79616.1 - 0.018 14.5 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Pox_A32 PF04665.7 KNZ79616.1 - 0.023 14.0 0.1 3.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein DEAD PF00270.24 KNZ79616.1 - 0.023 14.1 0.1 8.3 5.8 0.0 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase Dynamin_N PF00350.18 KNZ79616.1 - 0.038 13.7 1.1 3 7.6 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_19 PF13245.1 KNZ79616.1 - 0.039 13.7 0.0 2 8.2 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain IstB_IS21 PF01695.12 KNZ79616.1 - 0.041 13.2 0.0 3.3 7.1 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Arb1 PF09692.5 KNZ79616.1 - 0.076 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 PduV-EutP PF10662.4 KNZ79616.1 - 0.089 12.2 0.1 4.5 6.7 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.1 KNZ79616.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 KNZ79616.1 - 0.11 12.0 0.4 4 7.0 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 KNZ79616.1 - 0.12 12.3 0.0 4.4 7.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 KNZ79616.1 - 0.13 11.3 0.1 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.1 KNZ79616.1 - 0.15 11.0 0.0 0.37 9.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.10 KNZ79616.1 - 0.19 11.5 0.0 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit cobW PF02492.14 KNZ79616.1 - 0.2 11.0 0.9 2.2 7.6 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.4 KNZ79616.1 - 0.21 10.1 0.6 3.5 6.0 0.1 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RRM_1 PF00076.17 KNZ79617.1 - 5.1e-14 51.6 0.1 7.2e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ79617.1 - 4.9e-10 39.2 0.0 7.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ79617.1 - 4.4e-09 36.0 0.1 6.6e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 KNZ79617.1 - 1.7e-08 33.9 4.2 3.4e-08 33.0 2.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 KNZ79617.1 - 8.2e-05 22.2 0.0 0.00028 20.5 0.0 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 KNZ79617.1 - 0.0011 18.5 0.1 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 KNZ79617.1 - 0.088 12.3 6.1 0.032 13.7 1.9 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RRM_3 PF08777.6 KNZ79617.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif Glyco_hydro_72 PF03198.9 KNZ79618.1 - 4.4e-93 311.7 0.4 7.3e-93 310.9 0.2 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KNZ79618.1 - 5.1e-19 68.5 0.4 1.8e-18 66.7 0.3 2.0 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 KNZ79618.1 - 0.02 14.1 0.1 0.059 12.5 0.0 1.7 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) SUR7 PF06687.7 KNZ79619.1 - 2.1e-10 40.5 8.7 2.6e-10 40.2 6.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KNZ79619.1 - 8.1e-05 22.3 5.9 9.8e-05 22.1 4.1 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Bac_surface_Ag PF01103.18 KNZ79619.1 - 0.014 14.8 0.5 0.016 14.7 0.3 1.1 1 0 0 1 1 1 0 Surface antigen DUF2231 PF09990.4 KNZ79619.1 - 0.36 11.1 5.1 1.3 9.3 3.0 2.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF1700 PF08006.6 KNZ79619.1 - 0.4 9.9 3.0 0.68 9.1 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Glyco_transf_28 PF03033.15 KNZ79620.1 - 2.5e-26 92.0 0.0 5.1e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 KNZ79620.1 - 5.7e-20 70.6 1.4 2.4e-10 39.7 0.1 3.5 3 0 0 3 3 3 3 GRAM domain PH PF00169.24 KNZ79620.1 - 2.4e-15 56.5 0.9 3.2e-13 49.7 0.1 3.4 3 0 0 3 3 3 1 PH domain PH_6 PF15406.1 KNZ79620.1 - 4.2e-06 26.7 0.1 2.3e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 KNZ79620.1 - 3.3e-05 24.0 2.3 0.0014 18.8 1.1 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.13 KNZ79620.1 - 0.00011 20.8 0.0 0.00025 19.7 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.1 KNZ79620.1 - 0.0018 18.1 0.1 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 PH domain 2OG-FeII_Oxy PF03171.15 KNZ79621.1 - 0.00012 22.3 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KNZ79621.1 - 0.00075 20.0 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal RIC1 PF07064.8 KNZ79622.1 - 1.3e-73 247.6 0.1 2.5e-71 240.1 0.1 2.4 1 1 0 1 1 1 1 RIC1 PRELI PF04707.9 KNZ79623.1 - 7.1e-13 48.4 0.0 8.8e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Bac_DnaA PF00308.13 KNZ79623.1 - 0.035 13.7 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein MMR_HSR1 PF01926.18 KNZ79625.1 - 8.4e-19 67.6 0.0 1.6e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 KNZ79625.1 - 2.5e-18 65.6 0.0 4.2e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 KNZ79625.1 - 1.1e-10 40.9 0.0 1.9e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KNZ79625.1 - 0.0005 19.9 0.2 0.035 13.9 0.0 2.4 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 KNZ79625.1 - 0.0019 18.6 0.2 0.0055 17.1 0.0 1.9 2 1 0 2 2 2 1 Miro-like protein ArgK PF03308.11 KNZ79625.1 - 0.017 13.8 0.0 0.036 12.8 0.0 1.5 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 KNZ79625.1 - 0.022 13.5 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AAA_16 PF13191.1 KNZ79625.1 - 0.049 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.20 KNZ79626.1 - 9.4e-63 211.7 0.0 2.4e-62 210.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79626.1 - 6.7e-34 117.1 0.0 8.8e-26 90.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KNZ79626.1 - 5.5e-07 28.8 0.5 4.2e-06 25.9 0.1 2.5 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KNZ79626.1 - 0.0016 17.3 0.0 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KNZ79626.1 - 0.0059 16.3 0.4 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family B-block_TFIIIC PF04182.7 KNZ79627.1 - 4.8e-09 35.9 0.0 8.7e-07 28.6 0.0 3.3 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC HTH_27 PF13463.1 KNZ79627.1 - 0.04 14.2 0.0 1.2 9.5 0.0 3.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_24 PF13412.1 KNZ79627.1 - 0.094 12.1 0.0 6.1 6.3 0.0 3.2 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding PRELI PF04707.9 KNZ79628.1 - 2e-34 118.4 0.0 2.4e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Peptidase_M28 PF04389.12 KNZ79629.1 - 6e-27 94.5 0.0 1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 KNZ79629.1 - 0.0014 17.4 0.0 0.0025 16.6 0.0 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.23 KNZ79629.1 - 0.0031 17.0 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ABC_membrane_2 PF06472.10 KNZ79630.1 - 7.9e-83 277.8 5.7 1.1e-82 277.3 3.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KNZ79630.1 - 1.9e-16 60.6 0.0 4.4e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KNZ79630.1 - 0.00033 20.7 0.1 0.00069 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KNZ79630.1 - 0.017 14.6 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KNZ79630.1 - 0.018 15.3 0.9 0.025 14.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KNZ79630.1 - 0.019 14.9 0.4 0.069 13.1 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain SMC_N PF02463.14 KNZ79630.1 - 0.031 13.5 0.1 0.082 12.1 0.1 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KNZ79630.1 - 0.051 12.7 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Rad17 PF03215.10 KNZ79630.1 - 0.13 10.9 0.1 0.21 10.2 0.1 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NT5C PF06941.7 KNZ79631.1 - 4.2e-12 45.9 2.8 1.6e-11 44.0 0.3 2.4 2 1 0 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.1 KNZ79631.1 - 3.2e-07 30.7 0.2 1.3e-06 28.8 0.2 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KNZ79631.1 - 7.4e-05 23.2 0.0 0.00012 22.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 KNZ79631.1 - 0.0011 18.6 0.0 0.0033 17.0 0.0 1.7 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.2 KNZ79631.1 - 0.0093 16.1 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glycos_transf_N PF04413.11 KNZ79631.1 - 0.058 12.5 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Hydrolase_6 PF13344.1 KNZ79631.1 - 0.064 13.1 0.0 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase LNS2 PF08235.8 KNZ79631.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Pro_CA PF00484.14 KNZ79632.1 - 1.1e-27 96.8 0.1 1.3e-27 96.6 0.1 1.0 1 0 0 1 1 1 1 Carbonic anhydrase RINT1_TIP1 PF04437.8 KNZ79633.1 - 8.8e-81 271.9 0.6 4.7e-80 269.5 0.0 1.9 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Rbsn PF11464.3 KNZ79633.1 - 0.014 14.9 0.3 0.064 12.8 0.2 2.2 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Pkinase_Tyr PF07714.12 KNZ79634.1 - 1e-21 77.1 0.0 1.7e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ79634.1 - 8.4e-18 64.4 0.0 1.7e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain NTase_sub_bind PF08780.6 KNZ79634.1 - 0.036 13.8 0.2 0.099 12.4 0.1 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like MCM PF00493.18 KNZ79635.1 - 2.1e-125 417.9 0.0 3.4e-125 417.2 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KNZ79635.1 - 3.3e-23 82.4 0.1 7.2e-23 81.3 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KNZ79635.1 - 7.6e-08 31.7 0.1 1.4e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KNZ79635.1 - 0.0074 15.9 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KNZ79635.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 KNZ79635.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) WD40 PF00400.27 KNZ79636.1 - 1.2e-42 142.2 11.8 8.6e-11 41.2 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KNZ79636.1 - 0.0027 16.0 0.0 1 7.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 KNZ79636.1 - 0.0055 16.1 0.0 0.25 10.7 0.0 2.4 2 0 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 KNZ79636.1 - 0.021 12.9 0.3 0.54 8.3 0.2 2.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Myb_DNA-binding PF00249.26 KNZ79637.1 - 1.7e-36 123.9 4.6 1.5e-13 50.5 0.2 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KNZ79637.1 - 9.3e-35 118.5 1.6 1.1e-16 60.6 0.0 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 KNZ79637.1 - 0.043 13.6 4.7 17 5.3 0.8 3.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TPR_11 PF13414.1 KNZ79638.1 - 1.6e-26 91.7 5.4 4.9e-20 70.9 0.5 2.8 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 KNZ79638.1 - 4.2e-25 86.2 0.9 9.7e-08 31.3 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ79638.1 - 2.6e-21 73.7 0.3 2.6e-06 26.9 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ79638.1 - 1.3e-13 50.2 0.2 0.00017 21.9 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ79638.1 - 4.4e-13 47.9 2.1 4.6e-06 26.0 0.0 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ79638.1 - 7.6e-13 47.5 1.4 0.00072 19.5 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ79638.1 - 1.2e-11 44.8 2.7 2e-06 28.2 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ79638.1 - 3.9e-10 39.5 4.7 1.5e-06 27.9 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ79638.1 - 5.1e-09 35.2 0.8 2.7e-05 23.6 0.0 4.3 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ79638.1 - 1.7e-07 31.5 1.9 0.0018 18.5 0.0 2.7 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ79638.1 - 0.0002 21.5 0.8 0.13 12.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ79638.1 - 0.00085 19.1 0.0 0.01 15.6 0.0 2.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_15 PF13429.1 KNZ79638.1 - 0.0027 16.8 0.3 0.16 10.9 0.1 2.4 1 1 2 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 KNZ79638.1 - 0.021 15.1 0.0 3.7 7.8 0.0 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain Apc3 PF12895.2 KNZ79638.1 - 0.05 13.7 0.4 0.94 9.6 0.2 2.3 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KNZ79638.1 - 0.1 13.0 0.8 5.8 7.6 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat RPN7 PF10602.4 KNZ79638.1 - 0.24 10.7 0.8 30 3.9 0.0 2.9 1 1 2 3 3 3 0 26S proteasome subunit RPN7 TPR_10 PF13374.1 KNZ79638.1 - 0.59 10.1 2.8 1.8 8.5 0.0 3.1 4 0 0 4 4 3 0 Tetratricopeptide repeat BNIP3 PF06553.7 KNZ79638.1 - 7.3 5.9 6.8 6.8 6.0 1.1 2.1 2 0 0 2 2 2 0 BNIP3 Prp19 PF08606.6 KNZ79639.1 - 5.3e-31 106.1 2.1 1.1e-30 105.1 1.4 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 KNZ79639.1 - 2e-16 59.1 0.6 2.9e-06 26.9 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat U-box PF04564.10 KNZ79639.1 - 0.00016 21.5 0.0 0.00056 19.8 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.3 KNZ79639.1 - 0.042 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3312 PF11768.3 KNZ79639.1 - 0.067 11.4 0.0 0.1 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) OPT PF03169.10 KNZ79640.1 - 1.7e-191 637.8 59.8 2e-191 637.6 41.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SLD3 PF08639.5 KNZ79640.1 - 0.079 11.5 0.2 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 TauD PF02668.11 KNZ79641.1 - 1.4e-52 178.8 0.7 1.8e-52 178.6 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UPF0128 PF03673.8 KNZ79641.1 - 0.09 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) Cu-oxidase_3 PF07732.10 KNZ79641.1 - 0.091 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Multicopper oxidase DIE2_ALG10 PF04922.7 KNZ79642.1 - 6.6e-87 292.0 12.5 8.6e-87 291.6 8.7 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Spc7 PF08317.6 KNZ79644.1 - 2.1e-44 151.5 4.4 3.8e-44 150.6 3.1 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 KNZ79644.1 - 0.00024 20.6 0.1 0.00059 19.4 0.0 1.6 1 0 0 1 1 1 1 Spc7_C2 KaiC PF06745.8 KNZ79644.1 - 0.16 11.0 0.7 0.34 9.9 0.5 1.5 1 0 0 1 1 1 0 KaiC Atg14 PF10186.4 KNZ79644.1 - 1.2 8.0 8.5 2.2 7.1 5.1 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 KNZ79644.1 - 2.1 7.9 15.8 0.19 11.3 3.0 3.6 3 1 1 4 4 4 0 Mnd1 family Kinesin PF00225.18 KNZ79645.1 - 7e-79 264.9 0.0 1.3e-78 264.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF957 PF06117.6 KNZ79645.1 - 0.045 13.2 0.1 0.13 11.7 0.1 1.8 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) Tegument_dsDNA PF12818.2 KNZ79646.1 - 0.13 11.0 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein Mito_carr PF00153.22 KNZ79647.1 - 3.3e-16 58.7 0.0 4.3e-06 26.3 0.0 4.4 3 1 0 3 3 3 3 Mitochondrial carrier protein C2 PF00168.25 KNZ79648.1 - 7.1e-80 262.9 5.5 1.6e-19 69.5 0.0 5.6 5 0 0 5 5 5 5 C2 domain MFS_1 PF07690.11 KNZ79648.1 - 0.098 11.3 0.1 0.15 10.7 0.1 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF2404 PF10296.4 KNZ79648.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) Tfb2 PF03849.9 KNZ79649.1 - 8e-126 419.5 0.0 9.4e-126 419.3 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KNZ79649.1 - 0.00076 19.2 0.1 0.0025 17.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Methyltransf_26 PF13659.1 KNZ79650.1 - 1.7e-12 47.4 0.0 2.4e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ79650.1 - 7.5e-10 38.4 0.0 1e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KNZ79650.1 - 3.8e-05 23.3 0.0 5.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ79650.1 - 0.0028 18.0 0.0 0.011 16.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ79650.1 - 0.0034 17.7 0.0 0.011 16.0 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 KNZ79650.1 - 0.036 13.6 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 C2 PF00168.25 KNZ79651.1 - 5.6e-12 45.3 0.0 1.5e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 C2 domain NUDIX PF00293.23 KNZ79652.1 - 1.2e-08 34.7 0.0 2.1e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NPL4 PF05021.10 KNZ79653.1 - 4e-92 308.6 0.0 5e-92 308.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KNZ79653.1 - 3.2e-59 198.8 0.0 5.1e-59 198.1 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KNZ79653.1 - 7.3e-06 26.1 0.0 1.7e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RanBP PF00641.13 KNZ79653.1 - 2.7 7.1 7.6 0.058 12.5 0.7 1.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others bZIP_2 PF07716.10 KNZ79654.1 - 5.2e-09 35.7 11.3 3.8e-08 33.0 7.8 2.3 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 KNZ79654.1 - 1.3e-06 28.2 8.8 5.1e-06 26.3 6.1 2.0 1 1 0 1 1 1 1 bZIP transcription factor DUF1423 PF07227.6 KNZ79654.1 - 0.0027 16.4 0.6 0.003 16.2 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1423) DUF2216 PF10226.4 KNZ79654.1 - 0.024 14.1 2.2 0.035 13.6 1.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) Zwint PF15556.1 KNZ79654.1 - 0.032 13.4 2.3 0.04 13.1 1.6 1.1 1 0 0 1 1 1 0 ZW10 interactor Treacle PF03546.9 KNZ79654.1 - 0.13 10.9 14.7 0.31 9.7 3.7 2.0 2 0 0 2 2 2 0 Treacher Collins syndrome protein Treacle CHCH PF06747.8 KNZ79655.1 - 1.9e-05 24.4 5.6 2.9e-05 23.8 3.9 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 KNZ79655.1 - 0.015 15.3 3.5 0.052 13.5 2.5 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.8 KNZ79655.1 - 0.042 13.2 0.5 0.057 12.8 0.4 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCK PF07802.6 KNZ79655.1 - 0.062 13.4 1.9 0.098 12.7 1.3 1.2 1 0 0 1 1 1 0 GCK domain COX17 PF05051.8 KNZ79655.1 - 0.29 11.1 4.6 0.59 10.2 0.6 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GDPD PF03009.12 KNZ79656.1 - 1.4e-31 109.9 0.0 1.5e-26 93.4 0.0 2.2 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KNZ79656.1 - 1.3e-08 34.7 1.9 9.6e-08 31.9 0.8 2.3 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family UCR_TM PF02921.9 KNZ79657.1 - 2.2e-18 66.2 0.8 4e-18 65.3 0.5 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KNZ79657.1 - 1.2e-16 60.0 0.0 1.9e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF4149 PF13664.1 KNZ79658.1 - 3.6e-20 71.9 6.1 3.6e-20 71.9 4.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) LRR_9 PF14580.1 KNZ79659.1 - 4.8e-57 192.3 0.1 8.3e-57 191.5 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 KNZ79659.1 - 1.8e-12 46.5 4.8 4.7e-08 32.4 0.8 3.3 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNZ79659.1 - 4.7e-11 42.2 12.6 1.2e-07 31.4 2.9 2.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KNZ79659.1 - 0.00097 18.8 6.4 1.1 9.5 0.3 4.8 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 KNZ79659.1 - 0.002 18.0 2.6 3.2 8.3 0.3 4.4 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 KNZ79659.1 - 0.036 14.1 3.2 2.7 8.3 0.8 3.5 3 1 1 4 4 4 0 Leucine Rich repeat Syja_N PF02383.13 KNZ79660.1 - 1.9e-87 293.0 0.2 2.4e-87 292.6 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain NAP PF00956.13 KNZ79661.1 - 2.7e-30 105.2 0.6 4.5e-30 104.5 0.4 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Polysacc_deac_1 PF01522.16 KNZ79662.1 - 2.3e-32 111.2 0.0 4e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 KNZ79662.1 - 0.0048 15.8 0.0 0.007 15.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Pkinase PF00069.20 KNZ79663.1 - 8.8e-43 146.3 0.0 2.1e-22 79.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79663.1 - 1.8e-12 46.8 0.0 4e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KNZ79663.1 - 0.092 11.5 0.1 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KNZ79664.1 - 9.9e-53 178.9 0.0 1.4e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79664.1 - 7.4e-38 130.0 0.0 1.1e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ79664.1 - 0.00031 19.8 0.0 0.00077 18.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ79664.1 - 0.026 14.2 0.1 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MitMem_reg PF13012.1 KNZ79665.1 - 3e-21 75.6 0.0 4.2e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function MCM PF00493.18 KNZ79666.1 - 1.4e-142 474.3 0.2 1.8e-142 473.9 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KNZ79666.1 - 4.1e-18 66.0 0.0 1e-17 64.7 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KNZ79666.1 - 1.4e-06 27.6 0.0 0.00049 19.3 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KNZ79666.1 - 5.4e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KNZ79666.1 - 0.00034 20.2 0.2 0.0017 17.9 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 KNZ79666.1 - 0.0084 16.4 1.0 0.035 14.4 0.1 2.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 KNZ79666.1 - 0.044 13.9 0.2 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-C2H2 PF00096.21 KNZ79667.1 - 3.5e-08 33.3 18.9 3.4e-06 27.0 0.4 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ79667.1 - 8.7e-07 28.8 13.8 0.00022 21.3 0.5 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KNZ79667.1 - 0.0011 19.1 17.0 0.0012 18.9 1.3 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KNZ79667.1 - 0.024 14.7 5.8 0.12 12.5 0.5 3.2 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KNZ79667.1 - 8.5 6.8 6.8 2.1 8.7 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain PhoQ_Sensor PF08918.5 KNZ79668.1 - 0.4 10.1 3.2 0.55 9.7 0.8 1.9 2 0 0 2 2 2 0 PhoQ Sensor rve PF00665.21 KNZ79669.1 - 0.00017 21.6 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Methyltransf_2 PF00891.13 KNZ79671.1 - 7.5e-20 71.1 0.1 5.5e-18 65.0 0.0 2.9 2 1 0 2 2 2 1 O-methyltransferase DUF362 PF04015.7 KNZ79671.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF362) RRM_1 PF00076.17 KNZ79672.1 - 0.0055 16.3 0.1 0.45 10.1 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF724 PF05266.9 KNZ79672.1 - 0.22 11.1 6.2 0.38 10.3 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Phage_B PF02304.10 KNZ79672.1 - 1.2 9.4 3.7 0.64 10.3 0.7 1.9 2 0 0 2 2 2 0 Scaffold protein B PRA-PH PF01503.12 KNZ79673.1 - 5.2 7.4 7.5 20 5.5 5.2 2.1 1 1 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase RRM_1 PF00076.17 KNZ79674.1 - 7.6e-07 28.6 0.0 0.02 14.5 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ79674.1 - 0.00024 21.0 0.0 0.17 11.9 0.0 3.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cep57_CLD_2 PF14197.1 KNZ79674.1 - 0.03 14.2 7.2 1.3 8.9 3.4 3.0 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 RRM_3 PF08777.6 KNZ79674.1 - 0.099 12.4 2.8 3.5 7.5 0.0 3.7 2 1 1 3 3 3 0 RNA binding motif IncA PF04156.9 KNZ79674.1 - 0.19 11.2 8.5 0.36 10.3 5.9 1.4 1 0 0 1 1 1 0 IncA protein Bacillus_HBL PF05791.6 KNZ79674.1 - 0.2 11.0 6.1 0.57 9.5 4.2 1.8 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) CCDC-167 PF15188.1 KNZ79674.1 - 1.7 8.6 6.6 0.2 11.6 0.7 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Atg14 PF10186.4 KNZ79674.1 - 6 5.7 10.4 9.5 5.0 7.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KNZ79674.1 - 7.6 5.4 10.0 13 4.7 6.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Rad17 PF03215.10 KNZ79675.1 - 3.7e-56 190.8 0.0 3.9e-55 187.5 0.0 2.0 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 KNZ79675.1 - 8.3e-05 22.7 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KNZ79675.1 - 0.00043 20.3 0.0 0.0056 16.6 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 KNZ79675.1 - 0.00053 19.6 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KNZ79675.1 - 0.00064 19.8 0.0 0.0015 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ79675.1 - 0.011 16.6 0.0 0.035 14.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KNZ79675.1 - 0.012 15.1 0.1 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KNZ79675.1 - 0.043 14.1 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 KNZ79675.1 - 0.055 13.1 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 KNZ79675.1 - 0.14 12.3 0.2 0.6 10.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 KNZ79675.1 - 0.14 12.0 0.0 0.76 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KNZ79675.1 - 0.15 12.0 0.0 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Epimerase PF01370.16 KNZ79678.1 - 3.4e-20 72.5 0.0 1.5e-19 70.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KNZ79678.1 - 5.1e-13 48.3 0.0 1.1e-12 47.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KNZ79678.1 - 3.6e-11 43.3 0.4 9e-11 42.1 0.0 1.8 2 1 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 KNZ79678.1 - 5e-11 41.9 0.0 4.2e-09 35.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KNZ79678.1 - 0.0084 15.3 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 KNZ79678.1 - 0.13 11.1 0.1 0.23 10.3 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein UBX PF00789.15 KNZ79682.1 - 3.7e-09 36.5 0.0 9.8e-09 35.1 0.0 1.7 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.1 KNZ79682.1 - 2.3e-06 27.0 0.0 4.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain DBINO PF13892.1 KNZ79682.1 - 0.28 11.1 5.5 0.45 10.5 3.8 1.2 1 0 0 1 1 1 0 DNA-binding domain TFIIE_alpha PF02002.12 KNZ79683.1 - 2.6e-17 62.2 0.2 5.6e-17 61.1 0.1 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 KNZ79683.1 - 2e-05 23.8 0.7 4.9e-05 22.5 0.5 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding RecO_N_2 PF13114.1 KNZ79683.1 - 0.00027 20.5 0.1 0.00057 19.5 0.0 1.5 1 0 0 1 1 1 1 RecO N terminal TFIIE-A_C-term PF11521.3 KNZ79683.1 - 0.017 15.0 1.4 0.048 13.5 0.1 2.4 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha YppF PF14178.1 KNZ79683.1 - 0.028 13.9 0.0 0.23 11.0 0.0 2.3 2 0 0 2 2 2 0 YppF-like protein PhnA_Zn_Ribbon PF08274.7 KNZ79683.1 - 0.28 11.0 2.4 3.3 7.5 1.7 2.3 1 1 1 2 2 2 0 PhnA Zinc-Ribbon ThiF PF00899.16 KNZ79684.1 - 0.00014 21.7 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family 3-HAO PF06052.7 KNZ79686.1 - 2.8e-57 192.3 0.0 3.1e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KNZ79686.1 - 3.6e-06 26.3 0.0 5.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KNZ79686.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_1 PF00190.17 KNZ79686.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Cupin ARD PF03079.9 KNZ79686.1 - 0.061 13.2 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Med6 PF04934.9 KNZ79688.1 - 5e-38 129.8 0.2 7.4e-38 129.2 0.2 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component HAUS5 PF14817.1 KNZ79688.1 - 0.025 13.1 0.3 0.033 12.7 0.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Clat_adaptor_s PF01217.15 KNZ79689.1 - 6.1e-38 129.7 0.1 9.6e-38 129.0 0.0 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain ATP-synt_F PF01990.12 KNZ79690.1 - 1e-32 112.3 0.1 1.1e-32 112.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 KNZ79690.1 - 0.0028 16.6 0.0 0.0029 16.6 0.0 1.1 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Histone PF00125.19 KNZ79691.1 - 4.9e-29 100.2 0.8 9.2e-29 99.3 0.6 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TIM21 PF08294.6 KNZ79691.1 - 1.1e-19 70.5 0.0 2.8e-18 65.9 0.0 2.2 2 0 0 2 2 2 1 TIM21 CENP-S PF15630.1 KNZ79691.1 - 0.00012 22.2 0.1 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KNZ79691.1 - 0.0059 16.6 0.1 0.015 15.3 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KNZ79691.1 - 0.13 12.0 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Chalcone PF02431.10 KNZ79692.1 - 7.4e-26 90.7 0.0 1.2e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Chalcone-flavanone isomerase PhyH PF05721.8 KNZ79692.1 - 0.016 15.2 0.0 0.23 11.4 0.0 2.4 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) DUF3437 PF11919.3 KNZ79693.1 - 9.4e-24 82.9 0.0 3.5e-23 81.1 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 KNZ79693.1 - 1.5e-06 27.7 3.9 0.00067 19.5 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 KNZ79693.1 - 0.00014 22.0 3.9 0.0026 18.0 0.1 4.5 5 1 1 6 6 6 1 HEAT repeats Vac14_Fab1_bd PF12755.2 KNZ79693.1 - 0.0052 17.1 0.0 0.086 13.2 0.0 2.9 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KNZ79693.1 - 0.011 16.1 0.3 0.63 10.6 0.0 4.3 3 1 0 3 3 3 0 HEAT-like repeat zf-CCCH PF00642.19 KNZ79694.1 - 2.7e-20 71.5 14.7 1.4e-11 43.7 2.0 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KNZ79694.1 - 0.02 14.8 0.4 0.02 14.8 0.3 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Choline_kinase PF01633.15 KNZ79695.1 - 3.8e-49 167.1 0.0 5.2e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KNZ79695.1 - 6.4e-13 48.9 0.0 9.6e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KNZ79695.1 - 0.044 12.9 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase zf-CCHC PF00098.18 KNZ79696.1 - 0.0057 16.5 6.6 0.0084 15.9 1.7 2.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 KNZ79696.1 - 8.5 6.1 11.4 0.85 9.3 0.2 2.8 3 0 0 3 3 3 0 Zinc knuckle PIF1 PF05970.9 KNZ79697.1 - 3.4e-16 59.1 0.2 5.1e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 KNZ79697.1 - 5.5e-07 27.7 0.0 6.1e-07 27.5 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ79697.1 - 0.0016 18.5 0.0 0.0027 17.8 0.0 1.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.9 KNZ79698.1 - 2.5e-24 85.8 0.0 2.9e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.9 KNZ79699.1 - 1e-20 74.0 0.1 1.1e-20 73.9 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase MFS_1 PF07690.11 KNZ79700.1 - 5.6e-28 97.6 62.1 7.8e-19 67.5 26.7 4.1 2 2 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ79700.1 - 4.7e-08 32.0 4.8 4.7e-08 32.0 3.4 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter CTDII PF01556.13 KNZ79701.1 - 2.3e-30 104.2 1.1 5.9e-23 80.5 0.0 3.1 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KNZ79701.1 - 1.9e-24 85.1 1.4 3.1e-24 84.4 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KNZ79701.1 - 2.3e-10 40.3 16.7 2.3e-10 40.3 11.6 1.9 2 0 0 2 2 2 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 KNZ79701.1 - 2.8 8.3 7.3 8.7 6.7 5.1 1.8 1 1 0 1 1 1 0 Cytochrome c3 HypA PF01155.14 KNZ79701.1 - 9.9 5.8 8.7 10 5.8 1.3 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family SET PF00856.23 KNZ79702.1 - 3.3e-10 40.5 0.0 3.5e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 SET domain Pkinase PF00069.20 KNZ79703.1 - 7.2e-51 172.8 1.4 1.5e-49 168.4 1.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79703.1 - 3.7e-18 65.5 0.3 9.5e-09 34.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KNZ79703.1 - 2.5e-07 30.6 0.1 3.2e-05 23.8 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ79703.1 - 0.029 13.9 0.1 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 KNZ79703.1 - 0.077 12.0 0.2 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KNZ79703.1 - 0.12 11.6 0.9 1.2 8.3 0.0 2.4 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL Aconitase_B_N PF11791.3 KNZ79703.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Aconitate B N-terminal domain CBM_5_12 PF02839.9 KNZ79704.1 - 8.5e-16 57.2 35.3 5.6e-12 45.0 2.6 3.7 4 0 0 4 4 4 2 Carbohydrate binding domain CBM_5_12_2 PF14600.1 KNZ79704.1 - 0.052 13.1 14.0 0.62 9.7 3.2 3.0 2 0 0 2 2 2 0 Cellulose-binding domain Glyco_hydro_18 PF00704.23 KNZ79705.1 - 6.8e-16 58.6 0.9 4.1e-15 56.0 0.6 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 RAP1 PF07218.6 KNZ79705.1 - 0.56 8.2 1.8 0.91 7.5 1.2 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DNA_pol_A_exo1 PF01612.15 KNZ79706.1 - 2e-15 56.7 0.0 2.9e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Translin PF01997.11 KNZ79710.1 - 1.4e-57 194.5 0.0 1.6e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Translin family DcpS_C PF11969.3 KNZ79711.1 - 0.021 15.0 0.2 0.048 13.8 0.1 1.6 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding DUF3437 PF11919.3 KNZ79712.1 - 3e-30 103.7 0.0 2.6e-29 100.7 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 KNZ79712.1 - 5.9e-09 35.2 1.6 0.0026 17.6 0.1 7.0 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 KNZ79712.1 - 1.5e-06 28.3 0.1 0.046 14.0 0.0 5.1 5 0 0 5 5 5 1 HEAT repeats HD_assoc PF13286.1 KNZ79712.1 - 0.0072 16.5 0.0 0.043 14.0 0.0 2.3 2 0 0 2 2 2 1 Phosphohydrolase-associated domain V-ATPase_H_N PF03224.9 KNZ79712.1 - 0.013 14.6 0.7 0.042 12.9 0.1 2.1 2 0 0 2 2 2 0 V-ATPase subunit H Arm PF00514.18 KNZ79712.1 - 0.019 14.8 1.9 0.23 11.3 0.0 3.8 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 KNZ79712.1 - 0.023 15.0 0.8 22 5.5 0.0 3.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KNZ79712.1 - 0.041 14.3 7.1 19 5.9 0.0 6.0 5 1 1 6 6 6 0 HEAT-like repeat Retinal PF15449.1 KNZ79713.1 - 0.34 8.5 3.0 0.44 8.1 2.1 1.1 1 0 0 1 1 1 0 Retinal protein zf-RVT PF13966.1 KNZ79714.1 - 0.0092 16.2 0.3 0.032 14.5 0.2 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase EXS PF03124.9 KNZ79715.1 - 1.6e-80 270.7 28.8 2.2e-80 270.2 19.9 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KNZ79715.1 - 1.6e-34 119.9 0.2 2.4e-25 89.8 0.0 2.3 2 0 0 2 2 2 2 SPX domain Macoilin PF09726.4 KNZ79716.1 - 1.2 7.3 6.3 1.2 7.3 4.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Mitofilin PF09731.4 KNZ79718.1 - 7.1e-20 71.1 9.9 7.6e-20 71.0 6.9 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein NAP PF00956.13 KNZ79718.1 - 0.04 13.0 1.9 0.039 13.0 1.3 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Blo-t-5 PF11642.3 KNZ79718.1 - 0.045 13.5 3.1 0.053 13.2 2.2 1.1 1 0 0 1 1 1 0 Mite allergen Blo t 5 DUF3135 PF11333.3 KNZ79718.1 - 1.3 9.2 4.9 2.3 8.4 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3135) OmpH PF03938.9 KNZ79718.1 - 1.7 8.5 7.0 1.9 8.4 4.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CDC73 PF05179.9 KNZ79719.1 - 2.6e-51 174.6 3.7 4.1e-51 173.9 2.6 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family CbiC PF02570.10 KNZ79719.1 - 0.16 11.3 0.1 1 8.7 0.0 2.0 2 0 0 2 2 2 0 Precorrin-8X methylmutase tRNA_int_end_N2 PF12928.2 KNZ79720.1 - 1.7e-20 72.2 0.0 3.1e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KNZ79720.1 - 0.0054 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Rhamno_transf PF11316.3 KNZ79720.1 - 1.2 8.2 2.7 6.6 5.8 0.1 2.2 2 0 0 2 2 2 0 Putative rhamnosyl transferase DnaB_bind PF10410.4 KNZ79721.1 - 0.04 13.9 0.2 0.94 9.5 0.0 2.7 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase ubiquitin PF00240.18 KNZ79722.1 - 1.3e-12 46.9 0.0 2.5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KNZ79722.1 - 6.4e-06 25.7 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like fn3 PF00041.16 KNZ79722.1 - 0.073 13.2 0.6 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 Fibronectin type III domain SOG2 PF10428.4 KNZ79722.1 - 0.24 10.0 0.1 0.24 10.0 0.0 2.2 1 1 1 2 2 2 0 RAM signalling pathway protein Cmc1 PF08583.5 KNZ79723.1 - 0.0006 19.5 0.3 0.0009 18.9 0.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 KNZ79723.1 - 0.0013 18.6 0.1 0.0018 18.2 0.1 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.8 KNZ79723.1 - 0.0026 17.6 0.7 0.0066 16.3 0.5 1.7 1 1 0 1 1 1 1 CHCH domain Viral_DNA_Zn_bi PF03728.8 KNZ79723.1 - 0.075 13.1 0.1 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 Viral DNA-binding protein, zinc binding domain DUF3128 PF11326.3 KNZ79723.1 - 0.4 10.8 2.2 1.9 8.6 1.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) DUF1771 PF08590.5 KNZ79723.1 - 0.47 10.5 3.5 0.41 10.6 1.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) UPF0086 PF01868.11 KNZ79724.1 - 5.8e-21 73.9 0.1 2.2e-20 72.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function UPF0086 Phage_Coat_A PF05357.8 KNZ79724.1 - 0.044 13.3 0.2 0.7 9.5 0.1 2.6 2 1 0 2 2 2 0 Phage Coat Protein A Cpn60_TCP1 PF00118.19 KNZ79725.1 - 3.2e-134 448.1 12.6 3.8e-134 447.9 8.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cytochrom_C PF00034.16 KNZ79726.1 - 2.6e-09 37.7 0.2 4.9e-09 36.8 0.2 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KNZ79726.1 - 2.4e-08 33.9 2.6 1.7e-07 31.2 1.8 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KNZ79726.1 - 0.00021 20.7 0.6 0.0019 17.6 0.1 2.2 2 1 0 2 2 2 1 Cytochrome c-550 domain Docking PF08990.6 KNZ79726.1 - 2.4 7.5 4.3 11 5.3 0.2 2.2 2 0 0 2 2 2 0 Erythronolide synthase docking SMC_N PF02463.14 KNZ79727.1 - 6.2e-44 149.8 0.0 1.3e-43 148.7 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KNZ79727.1 - 5.3e-28 97.3 0.1 5.3e-28 97.3 0.1 2.6 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KNZ79727.1 - 0.0002 21.4 0.8 0.0034 17.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KNZ79727.1 - 0.0015 18.4 0.0 0.0052 16.6 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ATG16 PF08614.6 KNZ79727.1 - 0.0021 17.9 9.6 0.0021 17.9 6.7 6.9 3 2 2 5 5 5 2 Autophagy protein 16 (ATG16) THOC7 PF05615.8 KNZ79727.1 - 0.0066 16.7 7.8 0.0066 16.7 5.4 6.4 2 2 4 6 6 6 1 Tho complex subunit 7 Reo_sigmaC PF04582.7 KNZ79727.1 - 0.15 11.1 23.6 1 8.4 0.0 4.8 4 1 2 6 6 6 0 Reovirus sigma C capsid protein DUF1192 PF06698.6 KNZ79727.1 - 0.42 10.4 33.7 0.37 10.6 1.3 7.8 6 1 1 7 7 7 0 Protein of unknown function (DUF1192) SQS_PSY PF00494.14 KNZ79728.1 - 1.4e-41 142.5 0.1 1.9e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase VQ PF05678.9 KNZ79728.1 - 0.087 11.8 0.5 0.22 10.6 0.0 1.8 2 0 0 2 2 2 0 VQ motif Bromo_TP PF07524.8 KNZ79729.1 - 1e-06 28.3 0.1 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 KNZ79729.1 - 0.013 15.5 0.2 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNZ79729.1 - 0.021 15.0 0.1 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinetochore component CENP-S DUF159 PF02586.9 KNZ79730.1 - 4.3e-48 163.6 0.0 6.1e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 IMPDH PF00478.20 KNZ79731.1 - 1.1e-134 448.8 0.0 2.7e-134 447.5 0.0 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KNZ79731.1 - 1.2e-16 60.1 0.3 4.3e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KNZ79731.1 - 3.9e-10 39.3 6.4 9.4e-08 31.5 3.2 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 KNZ79731.1 - 8e-10 38.0 2.2 2.1e-09 36.7 1.5 1.7 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KNZ79731.1 - 0.0002 20.7 3.2 0.00086 18.6 0.6 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 KNZ79731.1 - 0.0002 20.4 1.1 0.00039 19.5 0.7 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG UcrQ PF02939.11 KNZ79732.1 - 1.9e-08 33.9 0.0 2.2e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 UcrQ family DASH_Dam1 PF08653.5 KNZ79733.1 - 1e-13 50.7 1.2 1e-13 50.7 0.8 1.7 2 0 0 2 2 2 1 DASH complex subunit Dam1 DUF4519 PF15012.1 KNZ79733.1 - 0.023 14.6 0.9 0.044 13.7 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) KSR1-SAM PF13543.1 KNZ79733.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 Cut8_N PF14482.1 KNZ79733.1 - 0.17 11.9 1.7 0.35 10.8 1.2 1.6 1 0 0 1 1 1 0 Cut8 proteasome-binding domain CUE PF02845.11 KNZ79734.1 - 6.3e-05 22.3 0.0 9.9e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain Pkinase PF00069.20 KNZ79735.1 - 2e-85 286.0 0.0 2.3e-48 164.6 0.0 3.1 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79735.1 - 2e-69 233.5 0.0 6.3e-33 113.9 0.0 3.4 2 1 1 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 KNZ79735.1 - 2.6e-10 39.7 0.0 3.8e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KNZ79735.1 - 0.00096 18.9 0.0 0.022 14.4 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ79736.1 - 1.3e-11 44.1 0.0 2.8e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79736.1 - 0.014 14.4 0.0 0.04 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase tRNA-synt_2 PF00152.15 KNZ79738.1 - 1.5e-86 290.2 0.0 1.9e-86 289.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KNZ79738.1 - 3.1e-12 46.1 0.0 1.8e-11 43.7 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KNZ79738.1 - 1.3e-08 34.3 0.0 0.00021 20.5 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KNZ79738.1 - 0.0016 18.0 0.0 0.77 9.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) eIF-5a PF01287.15 KNZ79739.1 - 3.5e-26 90.9 0.4 5.1e-26 90.4 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KNZ79739.1 - 2.6e-05 23.7 0.8 4.8e-05 22.8 0.6 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KNZ79739.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain LIM PF00412.17 KNZ79740.1 - 8.3e-12 45.0 6.5 1.6e-11 44.1 4.5 1.5 1 0 0 1 1 1 1 LIM domain zf-DNA_Pol PF08996.5 KNZ79740.1 - 0.021 14.1 0.9 0.031 13.6 0.6 1.2 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger UPF0547 PF10571.4 KNZ79740.1 - 0.044 13.4 0.5 0.1 12.3 0.0 1.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-Mss51 PF13824.1 KNZ79740.1 - 0.059 13.2 1.5 0.68 9.8 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn-ribbon_8 PF09723.5 KNZ79740.1 - 0.066 13.1 3.2 5.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_3 PF14369.1 KNZ79740.1 - 0.65 10.0 4.5 18 5.4 0.1 2.8 2 0 0 2 2 2 0 zinc-finger zf-ribbon_3 PF13248.1 KNZ79740.1 - 0.82 8.9 4.9 0.72 9.1 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KNZ79740.1 - 0.84 9.4 10.7 0.29 10.9 3.1 2.5 3 0 0 3 3 3 0 Transposase zinc-ribbon domain DZR PF12773.2 KNZ79740.1 - 1.4 8.8 6.5 9.6 6.1 4.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-dskA_traR PF01258.12 KNZ79740.1 - 4.4 7.1 9.9 2.6e+02 1.4 3.0 3.2 1 1 1 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger PIH1 PF08190.7 KNZ79741.1 - 1.3e-27 97.1 0.0 4.1e-27 95.5 0.0 1.6 1 1 0 1 1 1 1 pre-RNA processing PIH1/Nop17 DAHP_synth_1 PF00793.15 KNZ79742.1 - 1.8e-69 233.4 0.1 1.1e-53 181.7 0.1 2.1 2 0 0 2 2 2 2 DAHP synthetase I family DAHP_synth_2 PF01474.11 KNZ79742.1 - 0.071 11.4 0.1 0.21 9.8 0.1 1.7 1 1 0 1 1 1 0 Class-II DAHP synthetase family Apc1 PF12859.2 KNZ79743.1 - 4.5e-08 33.2 0.0 1.2e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KNZ79743.1 - 0.054 13.7 10.2 0.99 9.7 0.0 4.4 5 0 0 5 5 5 0 Proteasome/cyclosome repeat zf-RanBP PF00641.13 KNZ79744.1 - 0.00043 19.3 18.0 0.001 18.1 2.9 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others AAA_12 PF13087.1 KNZ79745.1 - 1.8e-57 193.9 0.0 3.1e-57 193.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KNZ79745.1 - 3.3e-49 167.6 0.4 6.1e-49 166.7 0.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNZ79745.1 - 7.5e-12 44.8 0.2 3.1e-11 42.8 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KNZ79745.1 - 5.9e-09 35.7 0.0 6.5e-06 25.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain UvrD-helicase PF00580.16 KNZ79745.1 - 4.6e-06 26.1 0.5 9.5e-06 25.1 0.1 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 KNZ79745.1 - 0.00077 19.0 0.1 4.9 6.5 0.0 3.9 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase Nup54 PF13874.1 KNZ79745.1 - 0.0076 15.9 1.4 0.018 14.7 1.0 1.6 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 AAA PF00004.24 KNZ79745.1 - 0.01 15.9 0.1 0.37 10.9 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KNZ79745.1 - 0.043 13.9 0.1 0.21 11.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 KNZ79745.1 - 0.048 13.4 1.1 2.9 7.6 0.0 2.9 3 0 0 3 3 3 0 Flavivirus DEAD domain HSBP1 PF06825.7 KNZ79745.1 - 0.065 12.8 0.8 0.73 9.4 0.3 2.4 2 0 0 2 2 2 0 Heat shock factor binding protein 1 MtrG PF04210.8 KNZ79745.1 - 0.16 11.6 0.2 12 5.5 0.1 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF2075 PF09848.4 KNZ79745.1 - 1.4 7.8 4.5 0.95 8.3 0.2 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_12 PF13087.1 KNZ79746.1 - 8.5e-28 97.0 0.0 2e-27 95.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KNZ79746.1 - 1.5e-23 83.6 1.4 3e-13 49.8 0.0 3.2 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 KNZ79746.1 - 1.8e-11 43.5 0.3 1.4e-09 37.5 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KNZ79746.1 - 1.4e-06 28.0 0.0 0.0016 18.0 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KNZ79746.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain UvrD-helicase PF00580.16 KNZ79746.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain ResIII PF04851.10 KNZ79746.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PIF1 PF05970.9 KNZ79746.1 - 0.17 10.8 0.0 3.3 6.5 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase MFS_1 PF07690.11 KNZ79747.1 - 3.5e-11 42.4 0.2 4.2e-11 42.1 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ79747.1 - 0.0025 16.4 0.1 0.0031 16.1 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 KNZ79747.1 - 0.0095 14.3 0.0 0.0098 14.3 0.0 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein Aldo_ket_red PF00248.16 KNZ79748.1 - 6.7e-66 222.0 0.0 7.5e-66 221.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PSD2 PF07624.6 KNZ79748.1 - 0.076 12.6 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) Syja_N PF02383.13 KNZ79750.1 - 7e-86 287.8 0.0 1.1e-85 287.2 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain WD40 PF00400.27 KNZ79751.1 - 2.5e-81 264.8 31.5 2.1e-11 43.2 0.6 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 KNZ79751.1 - 6.1e-09 34.5 1.8 0.0083 14.3 0.0 4.1 5 0 0 5 5 5 3 Nucleoporin Nup120/160 NLE PF08154.7 KNZ79751.1 - 2.4e-07 30.6 0.0 4.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nucleoporin_N PF08801.6 KNZ79751.1 - 0.085 11.5 4.9 4.6 5.8 0.3 3.5 2 2 1 3 3 3 0 Nup133 N terminal like Proteasome_A_N PF10584.4 KNZ79751.1 - 0.16 11.3 0.1 25 4.2 0.0 2.9 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature IKI3 PF04762.7 KNZ79751.1 - 0.22 9.3 0.0 0.35 8.6 0.0 1.2 1 0 0 1 1 1 0 IKI3 family FAD_binding_1 PF00667.15 KNZ79752.1 - 1.1e-36 126.3 0.0 1.8e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KNZ79752.1 - 2.3e-25 89.2 0.0 4.4e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KNZ79752.1 - 5.1e-11 43.0 0.0 9.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain IBR PF01485.16 KNZ79754.1 - 2.6e-07 30.4 35.1 4e-06 26.6 4.7 3.5 3 0 0 3 3 3 2 IBR domain DUF221 PF02714.10 KNZ79754.1 - 0.52 9.1 2.4 0.24 10.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function DUF221 Ald_Xan_dh_C2 PF02738.13 KNZ79755.1 - 4e-164 546.9 0.1 1.9e-83 280.6 0.1 2.1 1 1 1 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KNZ79755.1 - 3.7e-40 137.1 0.0 7e-40 136.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 KNZ79755.1 - 1.5e-32 111.9 1.1 3e-32 111.0 0.8 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 KNZ79755.1 - 1.9e-29 101.5 0.2 8.1e-29 99.5 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 KNZ79755.1 - 9.9e-06 25.3 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain MOSC_N PF03476.11 KNZ79756.1 - 9.4e-18 64.0 0.0 2.3e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.14 KNZ79756.1 - 8.1e-15 54.4 0.0 4e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V zf-C2H2_4 PF13894.1 KNZ79757.1 - 7.6e-07 29.0 13.4 0.0021 18.2 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KNZ79757.1 - 0.00013 22.0 17.3 0.0038 17.4 2.0 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KNZ79757.1 - 0.00076 19.6 13.3 0.033 14.4 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-BED PF02892.10 KNZ79757.1 - 0.0023 17.6 6.6 0.2 11.4 0.2 2.6 1 1 1 2 2 2 2 BED zinc finger zf-C2H2_jaz PF12171.3 KNZ79757.1 - 0.047 13.8 0.5 17 5.6 0.1 3.2 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AA_permease_2 PF13520.1 KNZ79759.1 - 3.2e-42 144.5 54.0 4e-42 144.2 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease YjbE PF11106.3 KNZ79759.1 - 0.07 13.0 9.2 0.24 11.3 0.5 2.7 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE zf-RVT PF13966.1 KNZ79760.1 - 0.0015 18.7 0.5 0.0022 18.2 0.3 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-C4pol PF14260.1 KNZ79760.1 - 0.018 14.9 0.5 0.025 14.5 0.3 1.1 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta NPCBM_assoc PF10633.4 KNZ79762.1 - 0.08 12.9 0.2 0.091 12.8 0.1 1.1 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Rft-1 PF04506.8 KNZ79763.1 - 1.2e-44 152.6 2.6 1.2e-44 152.6 1.8 1.4 2 0 0 2 2 2 1 Rft protein SAP PF02037.22 KNZ79763.1 - 0.042 13.3 0.7 0.076 12.5 0.5 1.5 1 0 0 1 1 1 0 SAP domain PPR_3 PF13812.1 KNZ79764.1 - 4.2e-21 73.4 9.8 0.00027 20.9 0.0 7.5 7 0 0 7 7 7 5 Pentatricopeptide repeat domain PPR_2 PF13041.1 KNZ79764.1 - 3.4e-10 39.7 0.0 0.0014 18.5 0.0 4.6 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.15 KNZ79764.1 - 3.6e-06 26.5 6.4 4.9 7.3 0.0 8.1 9 1 0 9 9 9 2 PPR repeat TPR_14 PF13428.1 KNZ79764.1 - 0.0045 17.4 1.5 1.1 10.0 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat CBFD_NFYB_HMF PF00808.18 KNZ79765.1 - 6.6e-21 74.1 0.9 8.8e-21 73.7 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KNZ79765.1 - 3.8e-09 36.5 0.1 5.1e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KNZ79765.1 - 0.0044 16.8 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TAF PF02969.12 KNZ79765.1 - 0.064 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Ish1 PF10281.4 KNZ79766.1 - 6.3e-53 176.4 28.4 7.1e-09 35.5 0.2 7.8 8 0 0 8 8 8 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 KNZ79766.1 - 3.1e-07 29.8 4.7 0.027 14.0 0.0 6.5 6 1 0 6 6 6 1 HeH/LEM domain Slx4 PF09494.5 KNZ79766.1 - 0.00023 20.8 0.1 7.2 6.4 0.0 4.7 4 0 0 4 4 4 2 Slx4 endonuclease SAP PF02037.22 KNZ79766.1 - 0.0012 18.3 0.0 22 4.6 0.0 5.0 5 0 0 5 5 5 0 SAP domain DUF1754 PF08555.5 KNZ79766.1 - 0.01 16.3 3.8 0.033 14.7 2.7 1.9 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF3936 PF13072.1 KNZ79766.1 - 0.13 11.7 1.1 1.6 8.2 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3936) SAM_2 PF07647.12 KNZ79766.1 - 6.1 6.7 9.0 9.8 6.1 0.1 4.3 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) Aldo_ket_red PF00248.16 KNZ79767.1 - 6.1e-42 143.3 0.1 8.8e-42 142.8 0.1 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4034 PF13226.1 KNZ79767.1 - 0.024 13.7 0.1 0.036 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) Clp1 PF06807.9 KNZ79768.1 - 3.4e-09 36.7 0.0 8.3e-09 35.4 0.0 1.7 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KNZ79768.1 - 5.2e-08 32.7 0.0 9.4e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KNZ79768.1 - 0.0025 17.6 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KNZ79768.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 KNZ79768.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 KNZ79768.1 - 0.043 13.8 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain CobU PF02283.11 KNZ79768.1 - 0.043 13.2 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase RNA_helicase PF00910.17 KNZ79768.1 - 0.085 13.0 0.0 0.41 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase WGG PF10273.4 KNZ79769.1 - 6.8e-26 90.1 1.0 1.1e-25 89.5 0.1 1.7 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 KNZ79769.1 - 0.1 12.6 2.2 0.14 12.2 0.8 1.9 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) PBP1_TM PF14812.1 KNZ79769.1 - 0.11 12.7 1.8 0.24 11.7 1.0 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TIP49 PF06068.8 KNZ79770.1 - 4.2e-173 575.6 0.0 4.9e-173 575.4 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KNZ79770.1 - 5.3e-10 39.6 0.1 2.2e-06 27.9 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KNZ79770.1 - 3.8e-08 32.6 0.0 1.1e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KNZ79770.1 - 3.6e-07 30.3 0.0 3.1e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KNZ79770.1 - 1e-05 25.2 0.1 0.0045 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KNZ79770.1 - 1.3e-05 25.3 0.1 0.048 13.7 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KNZ79770.1 - 0.00059 19.5 0.0 0.0018 17.9 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KNZ79770.1 - 0.0011 18.9 0.0 0.0036 17.2 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KNZ79770.1 - 0.0029 17.0 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KNZ79770.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 KNZ79770.1 - 0.014 15.2 0.0 0.08 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KNZ79770.1 - 0.016 15.1 0.0 6 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KNZ79770.1 - 0.033 13.3 0.1 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KNZ79770.1 - 0.037 13.5 0.0 3.8 6.9 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 KNZ79770.1 - 0.047 12.7 0.6 0.081 12.0 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 KNZ79770.1 - 0.069 13.9 0.1 0.18 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.4 KNZ79770.1 - 0.097 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KNZ79770.1 - 0.13 12.0 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.11 KNZ79770.1 - 0.41 9.8 0.0 0.41 9.8 0.0 2.3 4 0 0 4 4 4 0 PhoH-like protein LBR_tudor PF09465.5 KNZ79771.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF500 PF04366.7 KNZ79772.1 - 1.1e-37 128.2 0.2 2e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KNZ79772.1 - 5.5e-17 60.8 0.1 1.2e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KNZ79772.1 - 7.3e-13 47.8 0.0 1.5e-11 43.6 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KNZ79772.1 - 7.7e-11 41.3 0.0 2.6e-09 36.4 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain rve PF00665.21 KNZ79774.1 - 0.034 14.2 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain HEAT PF02985.17 KNZ79775.1 - 5.4e-19 66.5 6.7 2.8e-05 23.7 0.0 7.1 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.1 KNZ79775.1 - 1.3e-12 47.8 0.0 2.7e-07 30.7 0.0 5.4 3 2 2 5 5 5 4 HEAT repeats HEAT_EZ PF13513.1 KNZ79775.1 - 3.6e-12 46.4 9.7 2.4e-05 24.6 0.0 7.0 6 1 1 7 7 7 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KNZ79775.1 - 1.2e-09 38.3 0.0 0.00045 20.5 0.0 3.6 2 1 2 4 4 4 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 KNZ79775.1 - 4.7e-07 29.6 0.8 0.15 11.6 0.0 5.1 4 1 1 6 6 6 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 KNZ79775.1 - 0.0023 16.3 0.0 0.0055 15.0 0.0 1.6 1 0 0 1 1 1 1 Adaptin N terminal region DUF4042 PF13251.1 KNZ79775.1 - 0.0026 17.2 3.3 4.3 6.7 0.0 4.8 4 1 1 5 5 5 1 Domain of unknown function (DUF4042) Cnd1 PF12717.2 KNZ79775.1 - 0.066 13.0 0.0 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Acetyltransf_1 PF00583.19 KNZ79777.1 - 1.8e-14 53.4 0.1 2.4e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KNZ79777.1 - 2.8e-06 27.0 0.3 8.1e-06 25.5 0.1 1.7 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 KNZ79777.1 - 3.3e-05 23.9 0.0 4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KNZ79777.1 - 7.2e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KNZ79777.1 - 0.01 15.9 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KNZ79777.1 - 0.026 14.3 0.1 0.032 14.0 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KNZ79777.1 - 0.049 13.5 0.1 0.069 13.1 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.20 KNZ79778.1 - 1.2e-06 28.5 0.0 3.7e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ79778.1 - 1.3e-05 25.0 0.0 3.7e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase G-alpha PF00503.15 KNZ79780.1 - 1.7e-125 418.7 1.0 2.1e-125 418.4 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KNZ79780.1 - 4.5e-17 61.8 0.9 3.5e-12 45.9 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KNZ79780.1 - 1.7e-05 24.0 1.6 0.00083 18.5 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KNZ79780.1 - 0.00031 21.2 0.2 0.28 11.7 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 KNZ79780.1 - 0.0094 15.8 0.1 0.25 11.3 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 KNZ79780.1 - 0.024 14.1 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KNZ79780.1 - 0.028 13.8 0.1 3.8 6.9 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain zf-CHC2 PF01807.15 KNZ79780.1 - 0.069 12.7 0.0 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger FtsK_SpoIIIE PF01580.13 KNZ79780.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Helitron_like_N PF14214.1 KNZ79781.1 - 5.4e-24 84.9 0.0 6.8e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ79781.1 - 0.0045 16.5 0.0 0.0053 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) Gemini_AL1 PF00799.15 KNZ79781.1 - 0.031 14.1 0.1 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain PIF1 PF05970.9 KNZ79783.1 - 5.2e-110 367.8 0.0 6e-110 367.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ79783.1 - 0.00018 21.1 0.0 0.00034 20.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KNZ79783.1 - 0.057 12.9 0.2 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KNZ79783.1 - 0.063 13.2 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.10 KNZ79783.1 - 0.098 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Herpes_Helicase PF02689.9 KNZ79784.1 - 7e-08 30.7 0.0 7.4e-08 30.6 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ79784.1 - 0.011 15.8 0.0 0.018 15.2 0.0 1.4 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain BBS2_C PF14782.1 KNZ79788.1 - 0.06 11.9 1.8 0.089 11.3 1.2 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal BEX PF04538.7 KNZ79788.1 - 0.083 13.1 0.7 2.6 8.3 0.3 2.3 2 0 0 2 2 2 0 Brain expressed X-linked like family DUF1192 PF06698.6 KNZ79788.1 - 0.48 10.2 4.1 0.16 11.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) HSP90 PF00183.13 KNZ79789.1 - 1.7e-120 402.9 5.6 1.7e-120 402.9 3.9 3.2 3 0 0 3 3 3 1 Hsp90 protein FF PF01846.14 KNZ79789.1 - 6.1e-29 99.7 18.0 1.9e-09 37.3 0.0 6.9 7 0 0 7 7 7 4 FF domain WW PF00397.21 KNZ79789.1 - 2.7e-09 36.7 2.9 4.5e-07 29.5 0.3 2.7 2 0 0 2 2 2 2 WW domain HATPase_c_3 PF13589.1 KNZ79789.1 - 3.8e-09 36.3 1.2 8.9e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KNZ79789.1 - 5.8e-07 29.2 0.0 1.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DCA16 PF15349.1 KNZ79790.1 - 0.34 10.2 2.9 0.74 9.1 2.0 1.6 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Kelch_4 PF13418.1 KNZ79791.1 - 6.8e-19 67.3 8.2 0.00051 19.7 0.1 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.1 KNZ79791.1 - 1.4e-17 63.2 15.3 0.0013 18.8 1.0 6.8 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 KNZ79791.1 - 1.1e-08 34.8 3.6 0.66 10.2 0.1 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 KNZ79791.1 - 7.5e-06 25.4 1.0 0.54 9.8 0.1 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 KNZ79791.1 - 1.1e-05 25.1 6.6 0.024 14.5 0.1 5.2 5 0 0 5 5 5 2 Kelch motif Cytochrom_B561 PF03188.11 KNZ79791.1 - 0.00044 20.0 2.1 0.001 18.8 1.5 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Kelch_2 PF07646.10 KNZ79791.1 - 0.053 13.3 3.0 18 5.2 0.1 4.5 5 0 0 5 5 5 0 Kelch motif DUF4131 PF13567.1 KNZ79791.1 - 0.4 10.0 11.1 0.21 10.9 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF975 PF06161.6 KNZ79791.1 - 5.4 6.6 11.1 0.18 11.5 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF975) RNR_inhib PF08591.5 KNZ79792.1 - 0.076 13.9 0.7 0.27 12.1 0.1 2.0 1 1 1 2 2 2 0 Ribonucleotide reductase inhibitor Cid2 PF09774.4 KNZ79793.1 - 3.8e-27 95.2 6.8 6e-27 94.6 4.7 1.3 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Methyltransf_6 PF03737.10 KNZ79793.1 - 0.14 12.0 0.1 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Demethylmenaquinone methyltransferase TFIIA_gamma_C PF02751.9 KNZ79793.1 - 0.19 11.5 2.8 0.74 9.6 0.0 2.5 2 1 1 3 3 3 0 Transcription initiation factor IIA, gamma subunit GILT PF03227.11 KNZ79794.1 - 3.2e-08 33.3 0.1 5.5e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Yos1 PF08571.5 KNZ79795.1 - 2.6e-26 91.5 3.2 4.6e-26 90.7 2.2 1.4 1 1 0 1 1 1 1 Yos1-like Ribosomal_L22 PF00237.14 KNZ79796.1 - 2.1e-19 69.4 0.1 3.1e-19 68.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribophorin_I PF04597.9 KNZ79797.1 - 6.1e-116 387.4 0.1 6.9e-116 387.2 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I Fimbrial_PilY2 PF14481.1 KNZ79797.1 - 0.049 13.0 0.1 0.12 11.8 0.1 1.7 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 PPR_2 PF13041.1 KNZ79799.1 - 2.8e-17 62.4 0.1 1.4e-10 40.9 0.0 4.9 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.15 KNZ79799.1 - 3.4e-07 29.7 2.5 0.022 14.7 0.0 5.0 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.1 KNZ79799.1 - 3.9e-07 29.8 6.3 0.01 16.0 0.0 5.5 6 1 0 6 6 6 2 Pentatricopeptide repeat domain Asp PF00026.18 KNZ79800.1 - 3e-26 92.4 0.1 3.5e-25 88.9 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease CD34_antigen PF06365.7 KNZ79800.1 - 0.0024 17.5 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family PepSY_TM_2 PF13703.1 KNZ79800.1 - 0.019 15.0 0.1 0.046 13.9 0.1 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix Asp_protease_2 PF13650.1 KNZ79800.1 - 0.023 15.2 0.0 3.7 8.1 0.0 2.8 2 0 0 2 2 2 0 Aspartyl protease TAXi_N PF14543.1 KNZ79800.1 - 0.12 12.3 0.9 11 5.9 0.1 2.9 2 1 1 3 3 3 0 Xylanase inhibitor N-terminal Herpes_gE PF02480.11 KNZ79800.1 - 0.12 10.6 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Shisa PF13908.1 KNZ79800.1 - 0.18 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Fe-ADH PF00465.14 KNZ79801.1 - 1e-90 304.0 0.0 1.3e-90 303.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KNZ79801.1 - 7.8e-14 51.5 0.0 3.6e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase His_biosynth PF00977.16 KNZ79802.1 - 2.7e-28 98.7 0.0 3.5e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribosomal_L29 PF00831.18 KNZ79803.1 - 6.6e-20 70.5 3.4 6.6e-20 70.5 2.4 1.9 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 KNZ79803.1 - 0.0075 16.5 1.2 0.011 16.0 0.8 1.4 1 1 0 1 1 1 1 Ribosomal protein S9/S16 MRP-L47 PF06984.8 KNZ79803.1 - 0.011 15.5 2.4 0.013 15.3 0.7 1.8 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Taeniidae_ag PF05596.6 KNZ79803.1 - 0.092 12.5 0.4 0.092 12.5 0.3 2.4 3 0 0 3 3 3 0 Taeniidae antigen SNAPc19 PF15497.1 KNZ79803.1 - 0.11 12.7 2.7 0.14 12.3 1.6 1.5 1 1 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 HLH PF00010.21 KNZ79803.1 - 0.12 12.0 0.4 0.12 12.0 0.2 1.8 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain Phage_Nu1 PF07471.7 KNZ79803.1 - 0.17 11.3 2.2 1.1 8.7 0.5 2.0 1 1 1 2 2 2 0 Phage DNA packaging protein Nu1 MitMem_reg PF13012.1 KNZ79803.1 - 0.23 11.5 4.2 0.6 10.2 0.0 2.3 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function SbcD_C PF12320.3 KNZ79803.1 - 0.41 10.6 4.1 0.77 9.8 0.3 2.2 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Med10 PF09748.4 KNZ79803.1 - 0.46 10.3 2.9 7.2 6.4 2.0 2.2 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Snapin_Pallidin PF14712.1 KNZ79803.1 - 0.66 10.3 9.0 4.9 7.5 1.8 2.1 1 1 1 2 2 2 0 Snapin/Pallidin Fib_alpha PF08702.5 KNZ79803.1 - 2.1 8.4 7.2 11 6.1 5.0 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF607 PF04678.8 KNZ79803.1 - 2.9 7.7 6.2 10 5.9 4.3 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF607 DUF2408 PF10303.4 KNZ79803.1 - 3.3 7.8 9.1 2.3 8.3 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Pkinase PF00069.20 KNZ79804.1 - 2.6e-72 243.1 0.0 3.8e-72 242.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79804.1 - 2.3e-48 164.5 0.0 4.1e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ79804.1 - 6.4e-06 25.3 0.0 0.00011 21.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KNZ79804.1 - 0.087 11.8 0.0 0.74 8.8 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family KCl_Cotrans_1 PF03522.10 KNZ79804.1 - 3 7.4 5.4 7.5 6.1 0.4 2.8 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) Polysacc_deac_1 PF01522.16 KNZ79805.1 - 4.7e-28 97.3 0.0 9.7e-28 96.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase TFIIF_alpha PF05793.7 KNZ79806.1 - 3.8e-09 35.4 51.3 1.8e-05 23.3 29.2 4.1 2 1 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HLH PF00010.21 KNZ79806.1 - 0.0084 15.7 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Lin-8 PF03353.10 KNZ79806.1 - 2.1 7.5 17.0 0.43 9.8 9.2 1.8 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist AAA PF00004.24 KNZ79807.1 - 9.3e-05 22.6 0.0 0.00063 19.9 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KNZ79807.1 - 0.0057 17.4 0.1 0.042 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KNZ79807.1 - 0.017 14.8 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.1 KNZ79807.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TIP49 PF06068.8 KNZ79807.1 - 0.019 13.7 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus T2SE PF00437.15 KNZ79807.1 - 0.025 13.4 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KNZ79807.1 - 0.032 13.7 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.10 KNZ79807.1 - 0.049 12.3 0.0 0.1 11.2 0.0 1.5 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KNZ79807.1 - 0.13 12.0 0.2 0.33 10.7 0.2 1.7 1 0 0 1 1 1 0 Part of AAA domain Cupin_8 PF13621.1 KNZ79808.1 - 4.5e-58 196.6 0.0 5.7e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KNZ79808.1 - 0.00049 19.4 0.1 0.00083 18.6 0.1 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.6 KNZ79808.1 - 0.0026 17.2 0.9 0.033 13.6 0.1 2.4 3 0 0 3 3 3 1 Cupin domain JmjC PF02373.17 KNZ79808.1 - 0.0043 17.2 0.0 0.0092 16.2 0.0 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase Ribosomal_L7Ae PF01248.21 KNZ79809.1 - 1.6e-23 81.9 1.6 1.6e-23 81.9 1.1 1.8 3 0 0 3 3 3 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Atg14 PF10186.4 KNZ79810.1 - 2.3e-06 26.7 7.2 2.3e-06 26.7 5.0 2.8 1 1 2 3 3 3 1 UV radiation resistance protein and autophagy-related subunit 14 DUF603 PF04645.7 KNZ79810.1 - 0.025 14.5 5.5 0.063 13.2 0.8 3.2 1 1 2 3 3 3 0 Protein of unknown function, DUF603 Lzipper-MIP1 PF14389.1 KNZ79810.1 - 0.15 12.1 4.1 4.7 7.3 0.0 3.6 4 0 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 APG6 PF04111.7 KNZ79810.1 - 0.22 10.5 22.3 0.2 10.6 8.8 2.7 1 1 0 2 2 2 0 Autophagy protein Apg6 UPF0184 PF03670.8 KNZ79810.1 - 0.51 10.5 5.8 6.9 6.9 1.4 3.8 2 2 0 3 3 3 0 Uncharacterised protein family (UPF0184) DUF948 PF06103.6 KNZ79810.1 - 0.52 10.1 3.9 8.7 6.2 0.0 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 KNZ79810.1 - 0.84 9.4 4.9 3.6 7.3 0.2 3.3 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lge1 PF11488.3 KNZ79810.1 - 6.1 7.1 10.0 3.8 7.7 0.1 4.0 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 Tup_N PF08581.5 KNZ79810.1 - 9.4 6.5 13.3 9.1 6.5 0.4 4.2 4 0 0 4 4 4 0 Tup N-terminal RFX_DNA_binding PF02257.10 KNZ79811.1 - 7e-26 90.1 0.0 2.4e-25 88.5 0.0 1.9 2 0 0 2 2 2 1 RFX DNA-binding domain NOA36 PF06524.7 KNZ79811.1 - 0.014 14.6 1.9 0.023 13.9 1.3 1.2 1 0 0 1 1 1 0 NOA36 protein AMP-binding PF00501.23 KNZ79814.1 - 1.3e-45 155.5 0.0 1.8e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MARVEL PF01284.18 KNZ79815.1 - 0.028 14.2 15.1 0.75 9.6 11.3 2.1 1 1 1 2 2 2 0 Membrane-associating domain DUF843 PF05814.6 KNZ79815.1 - 0.13 12.1 2.6 1 9.1 0.2 2.5 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) TraL PF07178.6 KNZ79815.1 - 0.19 11.7 0.1 0.19 11.7 0.1 2.3 2 1 0 2 2 2 0 TraL protein 7TMR-DISM_7TM PF07695.6 KNZ79815.1 - 0.39 10.3 15.3 1.3 8.6 10.6 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF1772 PF08592.6 KNZ79815.1 - 2 8.1 8.8 0.9 9.2 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) HupE_UreJ_2 PF13795.1 KNZ79817.1 - 0.0065 15.9 1.5 0.0082 15.6 1.0 1.1 1 0 0 1 1 1 1 HupE / UreJ protein MtrC PF04211.8 KNZ79817.1 - 0.039 12.9 0.2 0.049 12.6 0.1 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C GPI2 PF06432.6 KNZ79817.1 - 0.12 11.7 1.9 0.14 11.4 1.3 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase UQ_con PF00179.21 KNZ79818.1 - 6.5e-38 129.3 0.2 8e-38 129.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KNZ79818.1 - 0.075 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 UEV domain FimP PF09766.4 KNZ79819.1 - 5.7e-33 114.4 13.6 6.7e-33 114.2 9.4 1.0 1 0 0 1 1 1 1 Fms-interacting protein FATC PF02260.15 KNZ79819.1 - 0.002 17.5 0.4 0.0038 16.6 0.0 1.6 2 0 0 2 2 2 1 FATC domain MCPsignal PF00015.16 KNZ79819.1 - 0.022 14.3 2.2 0.3 10.6 0.4 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain pRN1_helical PF13010.1 KNZ79819.1 - 0.049 13.2 1.1 0.049 13.2 0.8 1.7 2 1 0 2 2 2 0 Primase helical domain DUF349 PF03993.7 KNZ79819.1 - 3.9 7.7 8.1 3 8.0 2.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) G6PD_C PF02781.11 KNZ79820.1 - 8e-105 349.8 0.0 5.2e-102 340.6 0.0 2.4 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KNZ79820.1 - 4e-61 206.4 0.0 5.8e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF1682 PF07946.9 KNZ79823.1 - 3.1e-67 226.7 0.1 3.5e-67 226.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) YajC PF02699.10 KNZ79823.1 - 0.36 10.5 1.3 6.4 6.5 0.0 2.9 3 0 0 3 3 3 0 Preprotein translocase subunit DUF2992 PF11208.3 KNZ79823.1 - 4.8 7.0 14.9 7.4 6.4 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) LON PF02190.11 KNZ79825.1 - 1.2e-25 90.3 0.0 1.9e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 KNZ79825.1 - 3.7e-09 36.4 27.2 9.1e-07 28.8 7.3 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ79825.1 - 4.8e-08 32.5 22.5 8.8e-06 25.2 7.7 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KNZ79825.1 - 1e-07 31.6 20.3 5.9e-05 22.8 1.5 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KNZ79825.1 - 2.8e-07 30.0 6.0 2.8e-07 30.0 4.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ79825.1 - 8.2e-06 25.5 30.6 8.7e-06 25.4 8.5 2.6 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 KNZ79825.1 - 2.9e-05 23.7 26.7 0.00041 20.0 7.6 2.5 2 0 0 2 2 2 2 zinc-RING finger domain Rad50_zn_hook PF04423.9 KNZ79825.1 - 0.18 11.3 5.6 3.7 7.1 0.1 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 KNZ79825.1 - 0.46 10.2 18.6 2.9 7.6 3.9 2.9 2 1 0 2 2 2 0 RING-type zinc-finger zf-P11 PF03854.9 KNZ79825.1 - 6.7 6.2 12.3 0.52 9.8 4.0 2.4 2 0 0 2 2 2 0 P-11 zinc finger UQ_con PF00179.21 KNZ79827.1 - 1.7e-19 69.6 0.0 3.3e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.16 KNZ79827.1 - 1.4e-05 24.8 3.6 3.2e-05 23.6 2.5 1.6 1 0 0 1 1 1 1 IBR domain Mito_carr PF00153.22 KNZ79828.1 - 1.9e-51 171.7 6.7 4e-18 64.9 0.4 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 KNZ79828.1 - 0.12 12.2 0.0 32 4.5 0.0 3.6 3 2 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF2435 PF10363.4 KNZ79829.1 - 1.1e-30 105.3 0.1 7e-30 102.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) HEAT_2 PF13646.1 KNZ79829.1 - 0.00024 21.3 4.4 1.2 9.5 0.1 5.4 4 2 2 6 6 6 2 HEAT repeats DUF2411 PF10304.4 KNZ79829.1 - 0.00046 19.6 0.6 0.0026 17.2 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2411) HEAT PF02985.17 KNZ79829.1 - 0.053 13.6 0.4 1.1e+02 3.3 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 KNZ79829.1 - 0.21 12.1 12.4 0.38 11.3 0.0 6.0 7 1 1 8 8 8 0 HEAT-like repeat Sedlin_N PF04628.8 KNZ79830.1 - 4.8e-27 94.4 0.1 5.5e-27 94.2 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region GTP_EFTU PF00009.22 KNZ79831.1 - 2.7e-48 163.8 0.0 3.7e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KNZ79831.1 - 2.4e-22 78.9 0.2 2.8e-11 43.4 0.0 2.8 1 1 1 2 2 2 2 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KNZ79831.1 - 4.5e-09 36.3 0.7 9.7e-09 35.2 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KNZ79831.1 - 4.4e-05 23.4 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.10 KNZ79831.1 - 0.038 13.5 1.8 0.047 13.1 0.0 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Miro PF08477.8 KNZ79831.1 - 0.057 13.9 0.0 0.19 12.2 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein G-alpha PF00503.15 KNZ79831.1 - 0.14 10.8 0.1 0.23 10.1 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF605 PF04652.11 KNZ79831.1 - 0.44 9.9 13.9 0.62 9.4 9.6 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KNZ79831.1 - 8 4.5 13.4 11 4.1 9.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SH3_9 PF14604.1 KNZ79832.1 - 1.9e-39 132.9 5.4 9.3e-14 50.7 0.1 3.7 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 KNZ79832.1 - 1.1e-35 120.8 8.3 5.7e-15 54.4 0.0 3.9 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 KNZ79832.1 - 3.6e-27 93.8 0.0 7.3e-27 92.8 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 KNZ79832.1 - 5.4e-23 80.2 0.4 3.3e-07 29.6 0.0 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 KNZ79832.1 - 4.5e-05 23.5 1.7 0.1 12.7 0.0 3.6 3 0 0 3 3 3 1 Bacterial SH3 domain hSH3 PF14603.1 KNZ79832.1 - 0.14 12.1 0.0 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Helically-extended SH3 domain Lin-8 PF03353.10 KNZ79832.1 - 0.16 11.2 6.1 0.46 9.7 4.2 1.8 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Usp PF00582.21 KNZ79832.1 - 0.4 10.8 5.7 0.53 10.4 3.1 1.9 2 0 0 2 2 2 0 Universal stress protein family RR_TM4-6 PF06459.7 KNZ79832.1 - 1 9.1 6.5 2.8 7.7 4.5 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MSP1_C PF07462.6 KNZ79832.1 - 2.6 6.3 4.5 9.3 4.5 3.1 1.9 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Sec7 PF01369.15 KNZ79833.1 - 2e-65 220.0 0.2 5.1e-65 218.7 0.1 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KNZ79833.1 - 3.2e-54 182.8 2.4 3.2e-54 182.8 1.7 2.7 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KNZ79833.1 - 2.8e-31 106.8 6.8 8.2e-31 105.3 0.3 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) HEAT PF02985.17 KNZ79833.1 - 0.00046 20.0 1.5 0.78 9.9 0.0 5.0 6 0 0 6 6 6 1 HEAT repeat DUF1539 PF07560.6 KNZ79833.1 - 0.064 13.1 0.0 6.7 6.5 0.0 3.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) DS PF01916.12 KNZ79834.1 - 2.4e-125 417.6 0.0 3.5e-125 417.0 0.0 1.2 1 0 0 1 1 1 1 Deoxyhypusine synthase 14-3-3 PF00244.15 KNZ79835.1 - 3e-32 111.6 0.0 3.5e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 KNZ79835.1 - 0.086 12.7 2.0 0.17 11.8 0.6 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat zf-CCHC PF00098.18 KNZ79836.1 - 2.2e-30 103.0 45.6 8.3e-07 28.6 2.4 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.1 KNZ79836.1 - 2e-08 33.7 32.0 0.013 15.1 0.7 5.7 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.1 KNZ79836.1 - 0.00032 20.3 36.9 0.00049 19.6 0.9 5.7 5 1 1 6 6 6 4 Zinc knuckle zf-CCHC_3 PF13917.1 KNZ79836.1 - 0.043 13.5 31.2 1 9.1 1.0 6.0 3 1 2 5 5 5 0 Zinc knuckle zf-CCHC_5 PF14787.1 KNZ79836.1 - 0.22 11.0 0.2 0.22 11.0 0.1 4.6 4 1 1 5 5 5 0 GAG-polyprotein viral zinc-finger Polyketide_cyc PF03364.15 KNZ79837.1 - 4.3e-23 81.7 0.0 5.5e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 KNZ79837.1 - 0.032 14.4 0.0 0.055 13.6 0.0 1.5 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport GST_N_3 PF13417.1 KNZ79838.1 - 1.1e-09 38.3 0.1 2.4e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KNZ79838.1 - 0.0056 16.6 0.0 0.0094 15.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KNZ79838.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KNZ79838.1 - 0.032 14.7 0.0 0.055 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KNZ79838.1 - 0.05 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GTP_EFTU_D2 PF03144.20 KNZ79838.1 - 0.052 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Chitin_synth_1 PF01644.12 KNZ79839.1 - 3.6e-64 215.4 0.1 5.8e-64 214.7 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KNZ79839.1 - 1e-27 95.6 0.1 2.2e-27 94.5 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KNZ79839.1 - 4e-24 84.8 0.0 4.5e-19 68.2 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KNZ79839.1 - 1.8e-10 40.8 2.0 1.8e-10 40.8 1.4 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KNZ79839.1 - 9.7e-06 25.5 0.0 4.3e-05 23.4 0.0 2.1 3 0 0 3 3 3 1 Glycosyltransferase like family 2 RNA_pol_Rpb4 PF03874.11 KNZ79840.1 - 4e-19 68.7 0.1 6.4e-19 68.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Spo12 PF05032.7 KNZ79841.1 - 3.1e-10 39.4 0.2 6.2e-10 38.5 0.2 1.5 1 0 0 1 1 1 1 Spo12 family Sel1 PF08238.7 KNZ79842.1 - 3.1e-15 56.2 15.2 2.7e-05 24.6 0.0 6.1 7 0 0 7 7 7 4 Sel1 repeat TPR_2 PF07719.12 KNZ79842.1 - 0.014 15.2 0.5 0.12 12.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ79842.1 - 0.1 12.2 0.3 1.6 8.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ras PF00071.17 KNZ79843.1 - 3.8e-46 156.4 0.2 4.3e-46 156.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ79843.1 - 3.9e-13 49.9 0.1 7.3e-13 49.0 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KNZ79843.1 - 2.3e-06 26.9 0.0 2.8e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KNZ79843.1 - 1.3e-05 25.1 0.1 0.00013 21.8 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KNZ79843.1 - 8.8e-05 22.0 0.2 0.00023 20.6 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KNZ79843.1 - 0.0011 18.5 0.2 0.012 15.2 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.5 KNZ79843.1 - 0.0015 17.7 0.0 0.0021 17.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KNZ79843.1 - 0.035 13.3 0.2 0.11 11.7 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.1 KNZ79843.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KNZ79843.1 - 0.14 12.1 0.0 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Glyco_hydro_2 PF00703.16 KNZ79844.1 - 4.5e-08 33.5 0.0 2.4e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KNZ79844.1 - 0.0012 17.8 0.0 0.0021 17.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 KNZ79844.1 - 0.0013 18.2 0.4 0.0043 16.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF1508 PF07411.7 KNZ79844.1 - 0.049 13.0 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1508) MFS_1 PF07690.11 KNZ79845.1 - 7.3e-36 123.5 32.6 8.7e-36 123.3 22.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-RING_2 PF13639.1 KNZ79846.1 - 3e-10 39.7 6.0 4.8e-10 39.0 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KNZ79846.1 - 4.1e-07 30.0 2.2 6.4e-07 29.4 1.5 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KNZ79846.1 - 1.3e-05 24.9 1.5 2.2e-05 24.2 1.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KNZ79846.1 - 7.2e-05 22.3 4.5 0.00013 21.4 3.1 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ79846.1 - 0.00014 21.5 6.6 0.00029 20.4 4.6 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KNZ79846.1 - 0.0013 18.7 9.5 0.0084 16.1 6.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KNZ79846.1 - 0.0068 16.1 1.7 0.0068 16.1 1.2 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 KNZ79846.1 - 0.02 14.4 6.1 0.12 11.9 4.3 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KNZ79846.1 - 0.023 14.2 2.8 0.03 13.8 1.4 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 KNZ79846.1 - 0.059 13.0 7.7 0.5 10.0 5.6 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KNZ79846.1 - 0.23 11.2 2.0 0.52 10.1 0.5 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KNZ79846.1 - 0.26 11.1 7.2 0.12 12.2 1.1 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KNZ79846.1 - 9.1 6.3 7.6 69 3.5 5.3 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain tRNA-synt_2c PF01411.14 KNZ79847.1 - 9.5e-07 27.4 0.0 1.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KNZ79847.1 - 0.00043 20.1 0.0 0.0009 19.0 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain MFS_1 PF07690.11 KNZ79848.1 - 8.7e-32 110.1 39.5 8.7e-32 110.1 27.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily NIF PF03031.13 KNZ79849.1 - 1.3e-46 158.1 0.0 2e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Snf7 PF03357.16 KNZ79850.1 - 2.6e-35 121.3 17.5 2.6e-35 121.3 12.1 1.5 2 0 0 2 2 2 1 Snf7 Indigoidine_A PF04227.7 KNZ79850.1 - 0.012 14.8 3.2 0.014 14.6 0.1 2.0 1 1 0 2 2 2 0 Indigoidine synthase A like protein Birna_RdRp PF04197.7 KNZ79850.1 - 0.15 10.0 5.4 0.17 9.8 3.7 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) SPOB_a PF14689.1 KNZ79850.1 - 0.21 11.1 2.7 0.26 10.8 0.0 2.4 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain Ribonuclease_3 PF00636.21 KNZ79850.1 - 0.66 10.4 3.7 0.99 9.8 2.5 1.5 1 1 0 1 1 1 0 Ribonuclease III domain F-actin_cap_A PF01267.12 KNZ79850.1 - 1.2 8.1 6.4 14 4.5 4.4 2.1 1 1 0 1 1 1 0 F-actin capping protein alpha subunit DUF29 PF01724.11 KNZ79850.1 - 2.2 8.0 8.8 0.58 9.9 1.8 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF29 Macoilin PF09726.4 KNZ79850.1 - 2.7 6.1 13.7 3.5 5.8 9.5 1.2 1 0 0 1 1 1 0 Transmembrane protein UPF0564 PF10595.4 KNZ79850.1 - 3.1 6.6 9.8 0.55 9.0 3.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 Atg14 PF10186.4 KNZ79850.1 - 5 5.9 16.0 7.4 5.4 10.6 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MecA_N PF05223.6 KNZ79850.1 - 5.2 7.1 7.8 1.9 8.5 0.1 2.2 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain TRAM_LAG1_CLN8 PF03798.11 KNZ79851.1 - 4.4e-40 137.3 19.1 5.1e-40 137.1 13.2 1.0 1 0 0 1 1 1 1 TLC domain RRM_1 PF00076.17 KNZ79852.1 - 4.7e-17 61.3 0.1 9.5e-08 31.5 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ79852.1 - 2e-12 46.7 0.1 3.4e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ79852.1 - 2e-08 34.0 0.0 0.00056 19.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Tim54 PF11711.3 KNZ79852.1 - 0.0087 14.6 0.9 0.012 14.2 0.6 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 PTCRA PF15028.1 KNZ79852.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Pre-T-cell antigen receptor DJ-1_PfpI PF01965.19 KNZ79853.1 - 4e-29 100.9 0.4 6.8e-29 100.2 0.3 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KNZ79853.1 - 1.3e-05 24.6 2.0 8.6e-05 21.9 1.4 2.2 1 1 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family BRCT PF00533.21 KNZ79853.1 - 0.065 13.3 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain TPR_3 PF07720.7 KNZ79853.1 - 0.13 12.1 0.5 5.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Mob1_phocein PF03637.12 KNZ79854.1 - 6.8e-74 247.2 0.0 7.9e-74 247.0 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family DEAD PF00270.24 KNZ79856.1 - 2.3e-36 124.8 0.0 3.6e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ79856.1 - 3.6e-23 81.2 0.0 6.4e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KNZ79856.1 - 0.12 12.5 0.1 0.67 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF302 PF03625.9 KNZ79857.1 - 0.00016 21.1 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF302 DUF3661 PF12400.3 KNZ79857.1 - 0.072 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Vaculolar membrane protein Dynamin_N PF00350.18 KNZ79859.1 - 1.6e-18 67.0 0.1 1.6e-18 67.0 0.1 4.0 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 KNZ79859.1 - 2.3e-05 24.3 1.2 0.0032 17.4 0.8 3.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KNZ79859.1 - 0.0021 17.5 1.9 0.036 13.5 0.0 3.2 3 0 0 3 3 3 1 FtsK/SpoIIIE family DUF258 PF03193.11 KNZ79859.1 - 0.009 15.2 0.0 0.071 12.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 KNZ79859.1 - 0.028 14.7 0.1 0.028 14.7 0.1 2.7 3 1 0 3 3 3 0 ABC transporter AAA_16 PF13191.1 KNZ79859.1 - 0.029 14.3 0.2 0.24 11.3 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 KNZ79859.1 - 0.098 12.2 0.2 0.29 10.6 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KNZ79859.1 - 0.49 10.3 7.6 0.32 10.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF3742 PF12553.3 KNZ79860.1 - 0.044 14.2 0.1 0.093 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) ATP_bind_1 PF03029.12 KNZ79861.1 - 6.4e-75 251.7 0.0 8.6e-75 251.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KNZ79861.1 - 0.00014 22.6 0.0 0.00022 22.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ79861.1 - 0.00032 20.7 0.0 0.0013 18.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain CbiA PF01656.18 KNZ79861.1 - 0.0012 18.2 0.0 0.0033 16.8 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 KNZ79861.1 - 0.0028 17.8 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KNZ79861.1 - 0.0041 16.6 0.1 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain ArsA_ATPase PF02374.10 KNZ79861.1 - 0.0066 15.5 0.0 0.0089 15.1 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase T2SE PF00437.15 KNZ79861.1 - 0.0098 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 KNZ79861.1 - 0.01 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.1 KNZ79861.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KNZ79861.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 KNZ79861.1 - 0.027 14.2 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 KNZ79861.1 - 0.041 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KNZ79861.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KNZ79861.1 - 0.081 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.10 KNZ79861.1 - 0.082 12.6 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 NTPase MobB PF03205.9 KNZ79861.1 - 0.086 12.5 0.0 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KNZ79861.1 - 0.088 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ArgK PF03308.11 KNZ79861.1 - 0.095 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_24 PF13479.1 KNZ79861.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KNZ79861.1 - 0.15 12.4 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 KNZ79861.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Sigma54_activat PF00158.21 KNZ79861.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.4 KNZ79861.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 KNZ79861.1 - 0.21 11.1 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mago-bind PF09282.5 KNZ79862.1 - 4.2e-13 48.6 2.7 7e-13 47.8 1.9 1.4 1 0 0 1 1 1 1 Mago binding Pox_Ag35 PF03286.9 KNZ79862.1 - 0.014 14.8 7.9 0.018 14.5 5.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM60A PF15396.1 KNZ79862.1 - 0.39 10.4 4.9 0.52 10.0 3.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CD52 PF15116.1 KNZ79862.1 - 1.2 8.9 4.4 2.4 8.0 3.1 1.4 1 0 0 1 1 1 0 CAMPATH-1 antigen Menin PF05053.8 KNZ79862.1 - 2.1 6.4 6.7 2.2 6.3 4.6 1.0 1 0 0 1 1 1 0 Menin FAM176 PF14851.1 KNZ79862.1 - 2.4 7.8 9.0 4 7.1 6.2 1.3 1 0 0 1 1 1 0 FAM176 family Vfa1 PF08432.5 KNZ79862.1 - 4.4 7.2 16.4 5.9 6.8 11.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.7 KNZ79862.1 - 8.9 6.1 11.1 11 5.8 7.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1640 PF07798.6 KNZ79863.1 - 2.5e-10 40.6 6.3 2.9e-10 40.4 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Phage_GP20 PF06810.6 KNZ79863.1 - 0.038 13.4 3.7 0.069 12.5 2.6 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 FlaC_arch PF05377.6 KNZ79863.1 - 0.088 12.7 4.5 4.6 7.2 0.2 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF3538 PF12057.3 KNZ79863.1 - 0.15 11.7 1.0 0.24 11.0 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3538) DUF1843 PF08898.5 KNZ79863.1 - 0.39 10.8 1.6 31 4.7 0.1 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) DUF1664 PF07889.7 KNZ79863.1 - 1.2 8.9 6.7 2.7 7.8 4.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) GST_N_3 PF13417.1 KNZ79864.1 - 4.1e-13 49.3 0.0 7e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KNZ79864.1 - 3.3e-11 43.0 0.0 5.7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KNZ79864.1 - 4.2e-11 42.8 0.0 9.5e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KNZ79864.1 - 1.9e-08 34.1 0.0 3.9e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KNZ79864.1 - 9.8e-07 28.5 0.1 1.8e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KNZ79864.1 - 0.011 16.2 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KNZ79865.1 - 1.1e-11 44.5 0.0 2.2e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KNZ79865.1 - 8.3e-11 41.9 0.0 1.5e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KNZ79865.1 - 4.4e-09 36.4 0.0 7.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KNZ79865.1 - 5.2e-09 35.8 0.1 1e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KNZ79865.1 - 2.6e-07 30.5 0.0 8.2e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KNZ79865.1 - 0.017 15.5 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GCV_T PF01571.16 KNZ79866.1 - 3.6e-13 49.3 0.0 1.4e-12 47.4 0.0 1.8 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KNZ79866.1 - 0.03 14.3 0.0 0.11 12.4 0.0 2.0 1 1 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain ACPS PF01648.15 KNZ79867.1 - 8.8e-20 70.6 0.0 1.2e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily WD40 PF00400.27 KNZ79868.1 - 1.2e-53 177.1 33.0 2.8e-08 33.3 0.3 11.0 11 0 0 11 11 11 9 WD domain, G-beta repeat DEAD PF00270.24 KNZ79869.1 - 7.2e-15 54.8 0.0 2.2e-14 53.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ79869.1 - 1.1e-09 38.0 0.0 2.7e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_1 PF00076.17 KNZ79870.1 - 5.7e-10 38.6 0.0 6.4e-09 35.3 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ79870.1 - 4e-07 29.9 0.0 1.2e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ79870.1 - 0.00088 19.0 0.0 0.0059 16.4 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Complex1_LYR_2 PF13233.1 KNZ79871.1 - 2.6e-11 43.9 0.1 5.3e-11 42.9 0.1 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Sua5_yciO_yrdC PF01300.13 KNZ79872.1 - 3.9e-52 176.0 0.0 5.9e-52 175.5 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KNZ79872.1 - 5.3e-24 84.6 0.0 1.2e-23 83.5 0.0 1.6 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding Phage_Treg PF04761.7 KNZ79872.1 - 0.19 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator HMG_box PF00505.14 KNZ79873.1 - 4.1e-13 49.4 0.1 6.6e-13 48.7 0.1 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box MFS_1 PF07690.11 KNZ79874.1 - 8.8e-31 106.8 18.9 1.3e-30 106.3 13.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily YrbL-PhoP_reg PF10707.4 KNZ79874.1 - 0.066 12.5 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Nucleo_P87 PF07267.6 KNZ79874.1 - 7.2 5.1 7.6 13 4.2 5.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Thiolase_N PF00108.18 KNZ79875.1 - 4.2e-41 140.6 0.1 6.2e-41 140.1 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KNZ79875.1 - 1.6e-39 134.0 0.4 2.4e-39 133.5 0.3 1.2 1 0 0 1 1 1 1 Thiolase, C-terminal domain Dodecin PF07311.7 KNZ79875.1 - 0.079 13.0 0.9 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 Dodecin Autophagy_act_C PF03987.10 KNZ79876.1 - 5.9e-10 39.1 2.3 1.2e-09 38.1 1.6 1.6 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ribosomal_S3Ae PF01015.13 KNZ79877.1 - 6e-85 283.4 4.8 7.1e-85 283.2 3.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 KNZ79877.1 - 0.017 14.4 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region mRNA_cap_C PF03919.10 KNZ79877.1 - 0.02 15.2 0.1 0.041 14.1 0.1 1.6 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Pribosyltran PF00156.22 KNZ79878.1 - 1.6e-16 60.1 0.0 1.9e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KNZ79878.1 - 0.0018 17.5 0.0 0.0027 16.9 0.0 1.5 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_3 PF15610.1 KNZ79878.1 - 0.077 11.8 0.0 0.13 11.1 0.0 1.4 2 0 0 2 2 2 0 PRTase ComF-like Glyco_hydro_47 PF01532.15 KNZ79879.1 - 9e-119 397.0 0.0 1.1e-118 396.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 KNZ79879.1 - 2.9e-07 30.0 0.0 5.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 PA domain Auto_anti-p27 PF06677.7 KNZ79880.1 - 2.2e-13 49.7 3.4 4.7e-06 26.2 0.1 2.7 2 1 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribonuclease_3 PF00636.21 KNZ79884.1 - 3.5e-39 133.7 0.0 5.2e-21 75.2 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KNZ79884.1 - 1.6e-22 79.7 0.0 2e-10 40.7 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease-III-like PAZ PF02170.17 KNZ79884.1 - 0.00038 19.7 0.0 0.0012 18.1 0.0 1.8 1 0 0 1 1 1 1 PAZ domain Dicer_dimer PF03368.9 KNZ79884.1 - 0.00071 19.2 0.0 0.0021 17.7 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain COX7C PF02935.11 KNZ79885.1 - 2.1e-12 46.6 2.6 3.2e-12 46.0 1.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Aldedh PF00171.17 KNZ79886.1 - 6.1e-178 591.8 0.1 6.8e-178 591.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KNZ79886.1 - 0.022 13.4 0.0 0.049 12.3 0.0 1.5 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Proteasome PF00227.21 KNZ79887.1 - 2.3e-60 203.1 0.0 3.2e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KNZ79887.1 - 2.5e-08 33.0 0.1 6.5e-08 31.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature AhpC-TSA PF00578.16 KNZ79888.1 - 2.1e-34 117.8 0.0 2.4e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KNZ79888.1 - 5.8e-14 51.8 0.0 6.1e-14 51.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KNZ79888.1 - 0.024 14.5 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Ssu72 PF04722.8 KNZ79889.1 - 5.8e-71 237.8 0.0 6.5e-71 237.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Syntaxin-18_N PF10496.4 KNZ79890.1 - 1.2e-10 41.0 0.4 5.6e-10 38.9 0.3 2.2 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus DUF4094 PF13334.1 KNZ79890.1 - 0.0063 16.8 2.9 0.054 13.8 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) LXG PF04740.7 KNZ79890.1 - 0.58 9.9 7.0 0.11 12.3 2.0 1.9 2 0 0 2 2 2 0 LXG domain of WXG superfamily SNARE_assoc PF09335.6 KNZ79891.1 - 2e-15 57.0 7.1 2e-15 57.0 4.9 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein IncA PF04156.9 KNZ79892.1 - 0.39 10.2 3.1 0.62 9.6 2.2 1.2 1 0 0 1 1 1 0 IncA protein Cys_Met_Meta_PP PF01053.15 KNZ79893.1 - 1.4e-56 191.5 0.0 3.2e-56 190.2 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Fungal_trans PF04082.13 KNZ79894.1 - 1.6e-20 73.0 0.2 4.2e-20 71.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ79894.1 - 5.9e-05 22.8 6.9 0.00011 22.0 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DPBB_1 PF03330.13 KNZ79895.1 - 4.1e-08 33.1 0.0 9.4e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SASRP1 PF15160.1 KNZ79895.1 - 0.0013 18.0 0.1 0.85 8.8 0.0 2.1 2 0 0 2 2 2 2 Spermatogenesis-associated serine-rich protein 1 WD40 PF00400.27 KNZ79896.1 - 2.1e-71 233.4 23.6 1.2e-10 40.8 0.1 11.8 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 KNZ79896.1 - 9.8e-21 73.7 1.4 1.9e-20 72.8 1.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KNZ79896.1 - 6.8e-12 44.2 11.5 0.0012 17.0 0.2 6.1 4 2 2 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KNZ79896.1 - 4.8e-05 22.2 13.1 0.5 9.0 0.5 6.1 2 2 4 6 6 6 3 Nup133 N terminal like Utp21 PF04192.7 KNZ79896.1 - 0.0013 17.8 1.9 0.056 12.5 0.1 2.2 2 0 0 2 2 2 2 Utp21 specific WD40 associated putative domain eIF2A PF08662.6 KNZ79896.1 - 0.012 15.2 1.2 10 5.7 0.0 4.2 2 1 3 5 5 5 0 Eukaryotic translation initiation factor eIF2A Peptidase_M18 PF02127.10 KNZ79897.1 - 1.7e-143 478.2 0.0 1.9e-143 478.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KNZ79897.1 - 0.00045 19.0 0.1 0.027 13.2 0.1 2.4 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Brix PF04427.13 KNZ79898.1 - 2.6e-45 154.4 1.0 4.4e-45 153.6 0.7 1.4 1 0 0 1 1 1 1 Brix domain ATE_C PF04377.10 KNZ79899.1 - 4.8e-43 146.2 0.2 7.8e-43 145.5 0.2 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KNZ79899.1 - 8.2e-23 80.0 4.5 1.8e-22 78.9 3.1 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus DASH_Dad4 PF08650.5 KNZ79900.1 - 8.9e-17 60.7 1.4 1e-16 60.5 1.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 ERK-JNK_inhib PF15002.1 KNZ79900.1 - 0.018 14.4 0.1 0.02 14.2 0.1 1.0 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor Dynactin_p22 PF07426.6 KNZ79900.1 - 0.056 12.7 0.1 0.063 12.5 0.1 1.1 1 0 0 1 1 1 0 Dynactin subunit p22 WD40 PF00400.27 KNZ79901.1 - 0.00042 20.0 0.6 0.38 10.7 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF1513 PF07433.6 KNZ79901.1 - 0.024 13.5 0.1 0.063 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) EF-hand_1 PF00036.27 KNZ79903.1 - 3.4e-25 85.3 8.7 5.2e-08 31.6 0.0 4.8 5 1 1 6 6 6 3 EF hand EF-hand_7 PF13499.1 KNZ79903.1 - 1.7e-21 76.0 2.2 3.1e-13 49.6 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KNZ79903.1 - 3.2e-20 70.1 3.5 5.8e-06 25.7 0.1 5.2 5 1 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 KNZ79903.1 - 7e-14 50.4 11.4 0.00013 21.1 0.5 5.2 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.1 KNZ79903.1 - 4.7e-12 45.3 8.5 0.00033 20.2 1.0 4.3 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 KNZ79903.1 - 9.6e-09 34.9 1.0 0.015 15.0 0.0 3.9 3 1 1 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KNZ79903.1 - 0.00057 19.7 0.3 0.052 13.4 0.1 3.2 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 KNZ79903.1 - 0.0022 17.9 0.6 1.4 8.9 0.0 3.3 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.6 KNZ79903.1 - 0.0028 17.7 0.1 0.48 10.4 0.0 3.0 3 1 0 3 3 3 1 EF hand S10_plectin PF03501.10 KNZ79903.1 - 0.024 14.5 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_10 PF14788.1 KNZ79903.1 - 0.085 12.5 0.9 35 4.1 0.0 3.5 4 0 0 4 4 4 0 EF hand DUF106 PF01956.11 KNZ79904.1 - 1.5e-42 144.9 0.0 2.3e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF106 DAZAP2 PF11029.3 KNZ79904.1 - 0.0061 17.0 2.7 0.01 16.3 1.9 1.3 1 0 0 1 1 1 1 DAZ associated protein 2 (DAZAP2) V-SNARE PF05008.10 KNZ79905.1 - 3.6e-23 81.5 7.0 3e-22 78.5 1.2 2.4 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 KNZ79905.1 - 2.6e-16 59.4 12.4 3.8e-16 58.9 4.6 3.2 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KNZ79905.1 - 0.00075 19.1 0.8 0.00075 19.1 0.6 2.2 2 1 0 2 2 2 1 Sec20 YqjK PF13997.1 KNZ79905.1 - 0.01 16.0 1.4 0.016 15.3 0.2 2.0 2 0 0 2 2 1 0 YqjK-like protein Laminin_I PF06008.9 KNZ79905.1 - 0.01 15.1 9.6 0.2 10.9 1.7 2.1 2 0 0 2 2 2 0 Laminin Domain I Sec8_exocyst PF04048.9 KNZ79905.1 - 0.032 13.8 3.2 1.2 8.7 0.1 3.0 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Fusion_gly PF00523.13 KNZ79905.1 - 0.036 12.1 1.2 0.097 10.7 0.1 1.9 2 0 0 2 2 2 0 Fusion glycoprotein F0 Nbl1_Borealin_N PF10444.4 KNZ79905.1 - 0.039 13.3 1.7 0.12 11.8 0.1 2.6 2 1 0 2 2 2 0 Nbl1 / Borealin N terminal Imm43 PF15602.1 KNZ79905.1 - 0.045 13.7 1.4 1.3 8.9 0.1 2.3 1 1 0 2 2 2 0 Immunity protein 43 DUF883 PF05957.8 KNZ79905.1 - 0.049 14.0 6.1 3.5 8.0 1.1 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Pex24p PF06398.6 KNZ79905.1 - 0.095 11.4 0.3 0.14 10.9 0.2 1.2 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF3753 PF12575.3 KNZ79905.1 - 0.1 12.3 0.7 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) DUF1664 PF07889.7 KNZ79905.1 - 0.22 11.3 3.5 3.2 7.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.6 KNZ79905.1 - 0.83 9.6 6.9 0.32 11.0 0.6 2.2 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DegS PF05384.6 KNZ79905.1 - 1.1 8.4 10.4 0.48 9.6 0.5 3.0 2 1 1 3 3 3 0 Sensor protein DegS SPX PF03105.14 KNZ79905.1 - 1.1 8.9 7.1 1.3 8.6 4.9 1.1 1 0 0 1 1 1 0 SPX domain Tropomyosin PF00261.15 KNZ79905.1 - 1.8 7.6 12.8 39 3.2 8.9 2.2 1 1 0 1 1 1 0 Tropomyosin ADIP PF11559.3 KNZ79905.1 - 2.7 7.8 14.0 0.41 10.5 1.2 2.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding SNARE PF05739.14 KNZ79905.1 - 3.5 7.3 10.0 0.64 9.7 2.3 3.0 3 1 1 4 4 4 0 SNARE domain YlqD PF11068.3 KNZ79905.1 - 5.2 7.1 9.1 3.8 7.5 1.3 2.3 2 0 0 2 2 2 0 YlqD protein TRAP-gamma PF07074.7 KNZ79906.1 - 0.019 14.4 0.6 0.21 11.0 0.0 2.3 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF3917 PF13055.1 KNZ79906.1 - 0.05 13.8 0.6 0.05 13.8 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3917) LSR PF05624.9 KNZ79906.1 - 8.7 6.1 10.5 2 8.2 2.8 2.5 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) TGS PF02824.16 KNZ79907.1 - 1.2e-23 82.6 0.0 2e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KNZ79907.1 - 1.3e-17 63.7 0.0 3.1e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KNZ79907.1 - 2e-08 33.7 0.2 5e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KNZ79907.1 - 0.0077 16.0 0.5 2.8 7.7 0.0 2.3 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 KNZ79907.1 - 0.0099 14.6 0.9 0.018 13.8 0.2 1.7 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 KNZ79907.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein DUF211 PF02680.9 KNZ79907.1 - 0.078 12.7 0.1 0.26 11.0 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Ribonuc_red_sm PF00268.16 KNZ79908.1 - 5.1e-103 343.9 1.4 7.5e-103 343.3 0.9 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Alg6_Alg8 PF03155.10 KNZ79908.1 - 1.7e-101 340.3 32.0 6.6e-100 335.1 19.1 2.3 2 1 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family VMA21 PF09446.5 KNZ79909.1 - 1.2e-11 44.3 4.7 1.7e-11 43.8 3.2 1.3 1 0 0 1 1 1 1 VMA21-like domain Claudin_2 PF13903.1 KNZ79909.1 - 0.0026 17.4 0.3 0.0029 17.3 0.2 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction 7tm_7 PF08395.7 KNZ79909.1 - 0.082 11.9 0.1 0.095 11.7 0.1 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor Ribonuc_red_sm PF00268.16 KNZ79910.1 - 9.9e-120 398.7 1.8 1.2e-119 398.5 1.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Aminotran_1_2 PF00155.16 KNZ79911.1 - 2e-38 132.2 0.0 2.4e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KNZ79911.1 - 0.0018 16.6 0.0 0.0033 15.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Peptidase_S26 PF10502.4 KNZ79912.1 - 5.6e-05 22.6 0.1 0.052 13.0 0.0 3.0 2 1 1 3 3 3 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 KNZ79912.1 - 6.1e-05 22.5 0.0 8.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Pkinase_Tyr PF07714.12 KNZ79913.1 - 2.4e-42 144.8 0.0 2.7e-30 105.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KNZ79913.1 - 5.9e-42 143.6 0.0 2.2e-31 108.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 KNZ79913.1 - 0.00057 18.9 0.0 0.01 14.7 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KNZ79913.1 - 0.0031 17.3 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KNZ79913.1 - 0.011 14.8 0.0 0.67 8.9 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3723 PF12520.3 KNZ79914.1 - 0.015 13.8 0.2 0.02 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) DUF1965 PF09248.5 KNZ79914.1 - 0.048 13.5 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) DUF788 PF05620.6 KNZ79916.1 - 7.4e-21 74.7 0.9 1.2e-20 74.0 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Myb_DNA-binding PF00249.26 KNZ79917.1 - 1.1e-41 140.5 7.6 2.5e-10 40.2 0.1 5.5 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KNZ79917.1 - 1e-35 121.6 8.1 8.5e-08 32.1 0.0 5.6 3 2 2 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KNZ79917.1 - 6.9e-09 35.7 14.4 0.0028 17.7 0.2 5.5 3 1 2 5 5 5 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 KNZ79917.1 - 0.00036 20.3 3.5 0.094 12.6 0.1 3.8 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 KNZ79917.1 - 0.0036 17.4 5.9 0.059 13.5 0.1 4.3 4 1 0 4 4 4 1 Alcohol dehydrogenase transcription factor Myb/SANT-like API5 PF05918.6 KNZ79917.1 - 8.1 4.8 8.1 17 3.7 5.6 1.5 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Bromo_TP PF07524.8 KNZ79918.1 - 7.9e-08 31.9 0.1 1.4e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 KNZ79918.1 - 1.1e-07 31.7 2.2 1.1e-07 31.7 1.5 2.8 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Flavokinase PF01687.12 KNZ79919.1 - 3.5e-36 123.8 0.0 4.1e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Ribosomal_S11 PF00411.14 KNZ79920.1 - 4.3e-07 30.0 0.0 5.6e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Patched PF02460.13 KNZ79921.1 - 1.2e-68 231.8 3.8 3.7e-41 140.9 0.0 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 KNZ79921.1 - 1.1e-45 154.8 3.9 1.1e-45 154.8 2.7 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 KNZ79921.1 - 3.3e-05 21.5 4.5 3.3e-05 21.5 3.1 1.7 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Folate_rec PF03024.9 KNZ79921.1 - 0.00013 21.6 1.8 0.00024 20.7 1.3 1.4 1 0 0 1 1 1 1 Folate receptor family MMPL PF03176.10 KNZ79921.1 - 0.00098 17.9 6.7 0.00098 17.9 4.7 2.8 2 1 0 2 2 2 1 MMPL family Diphthamide_syn PF01866.12 KNZ79922.1 - 1.9e-88 296.6 0.0 2.8e-88 296.1 0.0 1.3 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Pkinase PF00069.20 KNZ79923.1 - 1.5e-68 230.7 0.0 2e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79923.1 - 1.3e-29 103.0 0.0 1.8e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KNZ79923.1 - 2e-13 50.6 0.0 6.5e-13 48.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KNZ79923.1 - 8.4e-09 34.7 0.1 3.9e-07 29.3 0.0 2.8 2 1 1 3 3 3 1 Kinase-like C2 PF00168.25 KNZ79923.1 - 3.1e-05 23.7 0.1 0.0054 16.5 0.1 2.5 2 0 0 2 2 2 1 C2 domain APH PF01636.18 KNZ79923.1 - 0.0042 16.8 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KNZ79923.1 - 0.019 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Suc_Fer-like PF06999.7 KNZ79924.1 - 4.6e-38 131.5 0.0 8.9e-38 130.5 0.0 1.5 1 1 0 1 1 1 1 Sucrase/ferredoxin-like IpgD PF05925.7 KNZ79925.1 - 0.019 13.1 0.0 0.026 12.7 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD MRP-S26 PF14943.1 KNZ79925.1 - 0.23 11.0 0.9 0.64 9.5 0.0 1.9 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 Acyl-CoA_dh_1 PF00441.19 KNZ79926.1 - 1.5e-25 90.0 0.2 2.7e-25 89.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 KNZ79926.1 - 1.6e-12 47.8 0.3 3.1e-12 46.8 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KNZ79926.1 - 1.1e-11 43.9 0.1 2.3e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KNZ79926.1 - 0.017 15.7 0.0 0.045 14.3 0.0 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 KNZ79926.1 - 0.045 13.1 0.1 0.1 11.9 0.1 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Fungal_trans PF04082.13 KNZ79927.1 - 4e-35 120.9 0.0 6.4e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ79927.1 - 4.5e-08 32.8 15.5 8.6e-08 31.9 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NB PF04159.8 KNZ79927.1 - 1.2 8.8 2.7 3.3 7.4 1.9 1.7 1 0 0 1 1 1 0 NB glycoprotein Ribosomal_L19 PF01245.15 KNZ79928.1 - 6e-20 71.1 0.0 1e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 RRM_1 PF00076.17 KNZ79928.1 - 2.9e-17 62.0 0.0 1.1e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ79928.1 - 6.1e-15 54.9 0.0 1.5e-14 53.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ79928.1 - 1.2e-06 28.2 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IMD PF08397.6 KNZ79929.1 - 0.0003 20.1 1.9 0.00049 19.4 1.3 1.3 1 0 0 1 1 1 1 IRSp53/MIM homology domain BAR PF03114.13 KNZ79929.1 - 0.0027 17.2 1.0 0.0072 15.8 0.7 1.6 1 1 0 1 1 1 1 BAR domain Arfaptin PF06456.8 KNZ79929.1 - 0.0064 15.8 2.0 0.025 13.9 1.4 1.9 1 1 0 1 1 1 1 Arfaptin-like domain Vac_Fusion PF02346.11 KNZ79929.1 - 0.082 12.3 1.3 0.27 10.6 0.1 2.2 1 1 1 2 2 2 0 Chordopoxvirus fusion protein GrpE PF01025.14 KNZ79929.1 - 0.3 10.5 3.9 0.25 10.8 1.5 1.7 2 0 0 2 2 2 0 GrpE IncA PF04156.9 KNZ79929.1 - 5 6.6 6.3 10 5.6 4.4 1.5 1 0 0 1 1 1 0 IncA protein tRNA-synt_2 PF00152.15 KNZ79930.1 - 7.3e-98 327.4 0.0 7.3e-48 163.0 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KNZ79930.1 - 5.1e-06 26.2 0.0 9.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 KNZ79930.1 - 0.003 17.1 0.1 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) F-box-like PF12937.2 KNZ79931.1 - 4.9e-05 22.9 0.2 0.00012 21.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KNZ79931.1 - 0.0013 18.3 0.1 0.0026 17.4 0.1 1.4 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.28 KNZ79931.1 - 0.0054 16.3 0.7 0.017 14.7 0.0 2.4 2 1 0 2 2 2 1 F-box domain Exo_endo_phos PF03372.18 KNZ79932.1 - 0.0053 16.7 0.2 0.0054 16.7 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KNZ79932.1 - 0.0087 15.6 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RnaseA PF00074.15 KNZ79932.1 - 0.13 12.6 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 Pancreatic ribonuclease RNase_H PF00075.19 KNZ79934.1 - 0.00048 20.4 0.0 0.00071 19.9 0.0 1.2 1 0 0 1 1 1 1 RNase H APH PF01636.18 KNZ79936.1 - 2e-08 34.2 0.0 6.3e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KNZ79936.1 - 0.00035 19.9 1.0 0.084 12.2 0.1 2.7 3 0 0 3 3 3 2 RIO1 family Choline_kinase PF01633.15 KNZ79936.1 - 0.001 18.6 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KNZ79936.1 - 0.041 13.0 0.1 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain LRR_4 PF12799.2 KNZ79937.1 - 1.3e-05 24.6 3.5 1.8 8.2 0.0 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KNZ79937.1 - 0.0032 17.4 8.0 3.5 8.2 0.0 5.6 6 0 0 6 6 6 2 Leucine rich repeat LRR_8 PF13855.1 KNZ79937.1 - 0.0033 17.1 4.4 1 9.1 0.0 3.9 3 1 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 KNZ79937.1 - 0.36 11.0 5.7 9.6 6.6 0.1 4.8 5 1 0 5 5 5 0 Leucine Rich Repeat ABC_tran PF00005.22 KNZ79938.1 - 2.9e-43 147.4 0.1 9.8e-21 74.4 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KNZ79938.1 - 1.2e-13 51.7 6.9 2.5e-05 24.4 0.7 4.3 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 KNZ79938.1 - 6.8e-12 45.0 1.3 0.01 15.0 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KNZ79938.1 - 4e-08 32.6 2.8 0.0046 16.4 0.0 2.7 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KNZ79938.1 - 3.9e-07 30.9 0.1 0.0022 18.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KNZ79938.1 - 5.4e-07 29.9 0.6 0.0011 19.2 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KNZ79938.1 - 2.3e-06 27.7 0.0 0.017 15.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF87 PF01935.12 KNZ79938.1 - 2.5e-06 27.4 0.0 0.0013 18.5 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 KNZ79938.1 - 6.1e-06 25.8 0.1 0.013 14.9 0.0 2.9 3 0 0 3 3 3 2 AAA-like domain Miro PF08477.8 KNZ79938.1 - 8.4e-06 26.2 0.0 0.27 11.7 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein SbcCD_C PF13558.1 KNZ79938.1 - 1.6e-05 24.7 0.0 0.037 13.9 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 KNZ79938.1 - 2e-05 24.5 0.0 0.19 11.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.7 KNZ79938.1 - 2.1e-05 24.2 0.0 0.17 11.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain MobB PF03205.9 KNZ79938.1 - 3.1e-05 23.7 0.2 0.3 10.7 0.0 3.6 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KNZ79938.1 - 4.6e-05 23.5 0.0 0.21 11.8 0.0 2.9 2 0 0 2 2 2 2 RNA helicase DUF258 PF03193.11 KNZ79938.1 - 4.6e-05 22.6 0.0 0.08 12.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Chromo PF00385.19 KNZ79938.1 - 5.7e-05 22.6 0.3 0.00014 21.4 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA PF00004.24 KNZ79938.1 - 6.7e-05 23.0 0.0 1.5 8.9 0.0 3.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KNZ79938.1 - 8.6e-05 22.9 9.1 0.025 14.8 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.1 KNZ79938.1 - 0.00013 21.9 0.0 0.21 11.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain HEAT_2 PF13646.1 KNZ79938.1 - 0.0002 21.5 15.9 0.0064 16.7 0.2 4.2 3 1 0 3 3 3 1 HEAT repeats AAA_25 PF13481.1 KNZ79938.1 - 0.00025 20.5 0.9 0.43 9.9 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_15 PF13175.1 KNZ79938.1 - 0.00025 20.2 0.5 4.9 6.0 0.0 3.3 2 1 1 3 3 3 0 AAA ATPase domain AAA_33 PF13671.1 KNZ79938.1 - 0.00027 20.8 0.0 0.72 9.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 KNZ79938.1 - 0.00041 19.2 0.2 0.34 9.6 0.0 2.4 2 0 0 2 2 2 2 ArgK protein Arch_ATPase PF01637.13 KNZ79938.1 - 0.00044 20.0 0.1 2.3 7.8 0.0 3.4 3 0 0 3 3 3 1 Archaeal ATPase FtsK_SpoIIIE PF01580.13 KNZ79938.1 - 0.0022 17.5 0.3 0.53 9.7 0.0 3.0 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_13 PF13166.1 KNZ79938.1 - 0.0026 16.3 0.0 2.2 6.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain ATP-synt_ab PF00006.20 KNZ79938.1 - 0.0039 16.7 0.1 4.7 6.6 0.0 3.3 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain U3snoRNP10 PF12397.3 KNZ79938.1 - 0.0053 16.6 1.8 0.0097 15.8 0.3 2.1 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 DUF815 PF05673.8 KNZ79938.1 - 0.0071 15.3 0.2 2.2 7.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KNZ79938.1 - 0.0098 15.7 0.4 1.8 8.4 0.2 3.2 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 KNZ79938.1 - 0.012 14.6 0.1 0.12 11.3 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain Dynamin_N PF00350.18 KNZ79938.1 - 0.039 13.7 0.1 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.10 KNZ79938.1 - 0.041 13.5 0.2 4.6 6.9 0.0 2.6 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.17 KNZ79938.1 - 0.055 12.3 0.5 7 5.4 0.2 2.3 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 KNZ79938.1 - 0.065 12.6 2.4 6.5 6.1 0.1 3.7 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KNZ79938.1 - 0.068 13.1 12.8 0.042 13.8 0.4 4.5 3 2 0 3 3 3 0 AAA ATPase domain AAA_5 PF07728.9 KNZ79938.1 - 0.74 9.5 4.9 9 6.0 0.1 3.8 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) HEAT PF02985.17 KNZ79938.1 - 1 9.5 8.8 2 8.6 0.2 4.9 6 0 0 6 6 4 0 HEAT repeat HEAT_EZ PF13513.1 KNZ79938.1 - 3.6 8.1 13.9 39 4.9 0.8 5.4 3 2 2 5 5 5 0 HEAT-like repeat V_ATPase_I PF01496.14 KNZ79939.1 - 1.9e-263 875.8 0.0 2.2e-263 875.6 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SlyX PF04102.7 KNZ79939.1 - 0.024 15.0 0.5 0.19 12.0 0.2 2.3 2 0 0 2 2 2 0 SlyX Clusterin PF01093.12 KNZ79939.1 - 0.097 11.4 0.2 0.15 10.8 0.2 1.2 1 0 0 1 1 1 0 Clusterin APH PF01636.18 KNZ79940.1 - 2.9e-12 46.8 0.2 2.9e-12 46.8 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ79940.1 - 7.3e-07 28.9 0.0 9.3e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KNZ79940.1 - 0.033 13.3 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.17 KNZ79940.1 - 0.16 11.2 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 RIO1 family zf-C3HC4_3 PF13920.1 KNZ79941.1 - 2e-09 36.9 12.0 2e-09 36.9 8.3 1.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ79941.1 - 2.4e-09 37.0 11.7 4.3e-09 36.2 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ79941.1 - 5.1e-09 35.6 11.0 1e-08 34.6 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ79941.1 - 1.1e-07 31.5 13.4 2e-07 30.6 9.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KNZ79941.1 - 2.1e-06 27.3 11.4 2.1e-06 27.3 7.9 1.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KNZ79941.1 - 8.5e-05 22.3 11.2 0.00017 21.3 7.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KNZ79941.1 - 0.002 18.2 8.2 0.0028 17.7 5.7 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger FdhE PF04216.7 KNZ79941.1 - 0.0081 15.9 3.5 0.0096 15.6 2.4 1.1 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation zf-RING_4 PF14570.1 KNZ79941.1 - 0.027 14.0 11.5 0.15 11.7 7.9 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KNZ79941.1 - 0.062 13.1 5.0 0.098 12.5 3.4 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 KNZ79941.1 - 0.073 12.8 8.1 0.22 11.3 5.7 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DUF3376 PF11856.3 KNZ79941.1 - 0.11 11.8 0.6 0.12 11.6 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) zf-RING_UBOX PF13445.1 KNZ79941.1 - 0.15 11.7 9.4 0.32 10.7 6.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 KNZ79941.1 - 3.2 7.3 9.1 7 6.2 6.2 1.6 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit CBM_21 PF03370.8 KNZ79942.1 - 9.9e-26 89.9 0.0 1.5e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 KNZ79942.1 - 0.024 14.7 0.2 0.11 12.5 0.1 2.0 1 1 0 1 1 1 0 Carbohydrate binding domain (family 25) ChaB PF06150.7 KNZ79942.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 ChaB WD40 PF00400.27 KNZ79943.1 - 4.2e-52 172.2 21.6 1.6e-10 40.3 0.0 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 KNZ79943.1 - 2e-10 40.7 1.8 1.2e-05 25.0 0.1 3.1 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 KNZ79943.1 - 0.00033 19.6 0.0 0.00044 19.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region Apc4_WD40 PF12894.2 KNZ79943.1 - 0.00087 18.7 0.0 2.5 7.6 0.0 3.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 KNZ79943.1 - 0.0013 16.6 0.1 0.0023 15.8 0.1 1.4 1 0 0 1 1 1 1 IKI3 family Nucleoporin_N PF08801.6 KNZ79943.1 - 0.0038 16.0 0.5 8.2 5.0 0.0 3.4 1 1 2 3 3 3 2 Nup133 N terminal like DUF3312 PF11768.3 KNZ79943.1 - 0.036 12.3 0.0 0.063 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DPPIV_N PF00930.16 KNZ79943.1 - 0.041 12.4 0.9 0.23 9.9 0.6 2.0 1 1 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Herpes_gE PF02480.11 KNZ79945.1 - 0.026 12.8 0.0 0.033 12.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KNZ79945.1 - 0.028 14.8 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 KNZ79945.1 - 0.08 12.4 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Peptidase_C48 PF02902.14 KNZ79946.1 - 1.7e-11 44.1 0.4 3.2e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Syntaxin-6_N PF09177.6 KNZ79946.1 - 0.061 13.7 2.4 0.17 12.2 0.3 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DHC_N1 PF08385.7 KNZ79947.1 - 0.0041 15.5 0.0 0.0043 15.4 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Methyltransf_3 PF01596.12 KNZ79947.1 - 0.1 11.6 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase EphA2_TM PF14575.1 KNZ79949.1 - 0.014 15.8 0.0 0.028 14.8 0.0 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Yip1 PF04893.12 KNZ79949.1 - 0.053 13.0 0.1 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 Yip1 domain Syndecan PF01034.15 KNZ79949.1 - 0.079 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SRRM_C PF15230.1 KNZ79949.1 - 4 7.5 7.4 5.7 7.1 0.9 2.5 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus GPI-anchored PF10342.4 KNZ79950.1 - 0.0003 21.2 0.6 0.00043 20.6 0.4 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.4 KNZ79951.1 - 0.0012 19.2 0.1 0.0016 18.8 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family zf-C3HC4_3 PF13920.1 KNZ79952.1 - 4.5e-10 39.0 9.5 4.5e-10 39.0 6.6 3.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ79952.1 - 1.1e-09 38.1 26.1 1.1e-08 34.9 7.7 3.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.2 KNZ79952.1 - 1.9e-09 37.3 11.2 0.0071 16.5 0.2 4.8 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-RING_2 PF13639.1 KNZ79952.1 - 3.8e-09 36.2 25.8 3.8e-09 36.2 6.7 3.3 2 1 1 3 3 3 2 Ring finger domain zf-C2H2_jaz PF12171.3 KNZ79952.1 - 1e-08 35.0 17.2 0.00044 20.3 0.1 4.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-RING_5 PF14634.1 KNZ79952.1 - 2.2e-08 33.6 28.5 1.7e-06 27.6 6.8 3.2 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4 PF00097.20 KNZ79952.1 - 3.7e-08 32.8 10.7 3.7e-08 32.8 7.4 3.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KNZ79952.1 - 0.0002 21.1 10.7 0.0002 21.1 7.4 3.4 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KNZ79952.1 - 0.00022 21.2 4.4 0.00022 21.2 3.0 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C2H2_4 PF13894.1 KNZ79952.1 - 0.00022 21.3 23.4 0.076 13.3 0.1 5.5 5 1 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KNZ79952.1 - 0.0023 17.7 0.9 0.13 12.2 0.0 4.6 6 0 0 6 6 6 2 C2H2-type zinc finger Ecl1 PF12855.2 KNZ79952.1 - 0.0064 15.7 9.4 0.045 13.0 0.4 3.1 3 0 0 3 3 3 2 Life-span regulatory factor zf-C2H2 PF00096.21 KNZ79952.1 - 0.0065 16.7 2.6 0.11 12.9 0.2 5.5 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-RING_4 PF14570.1 KNZ79952.1 - 0.014 14.9 9.0 0.014 14.9 6.2 3.3 2 2 2 4 4 3 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KNZ79952.1 - 0.081 12.7 13.0 0.09 12.5 4.0 2.9 2 1 1 3 3 3 0 zf-RING of BARD1-type protein FYVE PF01363.16 KNZ79952.1 - 0.29 11.0 28.0 0.063 13.1 5.8 4.2 1 1 2 3 3 3 0 FYVE zinc finger zf-RING_UBOX PF13445.1 KNZ79952.1 - 1 9.1 18.9 0.063 13.0 6.3 2.9 2 1 0 2 2 2 0 RING-type zinc-finger zf-C2H2_2 PF12756.2 KNZ79952.1 - 4.7 7.3 20.0 2 8.5 5.3 4.1 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-Apc11 PF12861.2 KNZ79952.1 - 7.1 6.5 14.9 0.029 14.2 3.2 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-DBF PF07535.7 KNZ79952.1 - 7.3 6.3 15.7 0.67 9.6 0.3 3.6 3 1 1 4 4 4 0 DBF zinc finger Peptidase_M50B PF13398.1 KNZ79953.1 - 1.3e-50 171.5 19.7 1.3e-50 171.5 13.7 1.8 1 1 1 2 2 2 1 Peptidase M50B-like Cytochrom_B_C PF00032.12 KNZ79953.1 - 9.5 6.5 18.8 15 5.8 3.0 3.4 3 0 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Ras PF00071.17 KNZ79954.1 - 1.9e-58 196.3 0.1 2.5e-58 196.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ79954.1 - 7.8e-17 61.8 0.0 1.3e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ79954.1 - 2.7e-09 36.4 0.0 3.5e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 KNZ79954.1 - 1.6e-06 28.3 0.0 4.7e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 KNZ79954.1 - 4.1e-05 23.1 0.0 6.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KNZ79954.1 - 5.6e-05 22.3 0.1 8.9e-05 21.7 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KNZ79954.1 - 7.7e-05 22.6 0.1 0.00013 21.8 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KNZ79954.1 - 0.013 15.4 0.1 0.025 14.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 KNZ79954.1 - 0.046 12.9 0.0 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 YvfG PF09628.5 KNZ79954.1 - 0.12 12.5 0.1 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 YvfG protein AAA_5 PF07728.9 KNZ79954.1 - 0.13 12.0 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF718 PF05336.8 KNZ79955.1 - 8e-28 96.3 0.4 9e-28 96.1 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Lipoxygenase PF00305.14 KNZ79955.1 - 0.047 11.6 0.3 0.058 11.3 0.2 1.1 1 0 0 1 1 1 0 Lipoxygenase WD40 PF00400.27 KNZ79957.1 - 6.7e-13 47.9 1.0 0.0033 17.2 0.0 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat DUF2415 PF10313.4 KNZ79957.1 - 0.0075 15.9 0.0 0.079 12.6 0.0 2.6 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) Glycos_transf_1 PF00534.15 KNZ79958.1 - 5.1e-20 71.6 0.0 1.3e-18 66.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KNZ79958.1 - 1.6e-13 50.7 0.1 1.6e-11 44.2 0.1 2.3 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KNZ79958.1 - 2.4e-13 50.5 0.3 1.4e-11 44.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 KNZ79958.1 - 5.2e-08 33.1 0.0 5.5e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KNZ79958.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 DOPA_dioxygen PF08883.6 KNZ79959.1 - 9e-19 67.4 0.0 1.2e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family AA_kinase PF00696.23 KNZ79960.1 - 3.6e-42 144.5 1.1 5.6e-42 143.9 0.8 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KNZ79960.1 - 7.5e-11 41.5 0.2 1.8e-10 40.4 0.2 1.7 1 0 0 1 1 1 1 PUA domain Corona_nucleoca PF00937.13 KNZ79960.1 - 0.1 11.5 0.5 0.16 10.9 0.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Pribosyltran_N PF13793.1 KNZ79961.1 - 5.1e-50 168.0 1.4 1.4e-48 163.4 0.1 3.0 2 1 2 4 4 4 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KNZ79961.1 - 8.3e-38 129.9 1.8 1.8e-34 119.1 0.5 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KNZ79961.1 - 3.2e-14 52.7 0.2 4.3e-12 45.8 0.1 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain UPRTase PF14681.1 KNZ79961.1 - 4.3e-06 26.0 0.1 7.3e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 KNZ79961.1 - 0.064 12.5 0.1 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase Pkinase PF00069.20 KNZ79962.1 - 4.1e-18 65.4 0.0 7.3e-15 54.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79962.1 - 2.8e-08 33.1 0.0 2.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ79962.1 - 1.3e-05 25.0 0.0 0.00011 22.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family p450 PF00067.17 KNZ79964.1 - 1.7e-61 208.2 0.1 2.5e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_31 PF13847.1 KNZ79965.1 - 6.3e-12 45.3 0.0 1.3e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ79965.1 - 5e-09 36.5 0.0 1.5e-08 35.0 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ79965.1 - 9.1e-09 35.7 0.0 1.9e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ79965.1 - 3.3e-08 33.4 0.0 5.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ79965.1 - 9.8e-06 25.8 0.1 0.00016 22.0 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNZ79965.1 - 1.5e-05 24.2 0.0 2.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KNZ79965.1 - 7.8e-05 23.2 0.1 0.0012 19.3 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain IMS PF00817.15 KNZ79966.1 - 4.9e-40 136.7 0.0 8.5e-40 135.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KNZ79966.1 - 6.4e-15 55.2 0.0 3e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain PTCB-BRCT PF12738.2 KNZ79966.1 - 3.9e-07 29.8 0.0 8.4e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.3 KNZ79966.1 - 4.9e-07 29.4 0.0 2.3e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif BRCT PF00533.21 KNZ79966.1 - 9.3e-07 28.9 0.0 2.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF4414 PF14377.1 KNZ79966.1 - 0.034 14.0 0.3 1.3 8.9 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) NPV_P10 PF05531.7 KNZ79967.1 - 0.03 14.5 0.4 0.32 11.2 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Asp PF00026.18 KNZ79970.1 - 2.2e-31 109.2 0.0 1.1e-30 106.9 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNZ79970.1 - 6.9e-05 22.8 0.4 0.00014 21.8 0.3 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KNZ79970.1 - 0.048 14.1 0.3 0.32 11.5 0.0 2.5 3 0 0 3 3 3 0 Aspartyl protease Herpes_gE PF02480.11 KNZ79970.1 - 0.18 10.0 0.0 0.25 9.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E G-alpha PF00503.15 KNZ79971.1 - 6e-35 120.6 0.2 6.6e-35 120.5 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit zf-CHC2 PF01807.15 KNZ79971.1 - 0.02 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 CHC2 zinc finger Ovate PF04844.8 KNZ79971.1 - 0.15 11.8 0.3 9.3 6.1 0.0 2.2 1 1 1 2 2 2 0 Transcriptional repressor, ovate Asp PF00026.18 KNZ79973.1 - 3.2e-17 62.7 0.2 4.3e-17 62.3 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease ketoacyl-synt PF00109.21 KNZ79973.1 - 1.7e-06 27.7 0.0 2.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain TAXi_N PF14543.1 KNZ79973.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal ATG13 PF10033.4 KNZ79974.1 - 7.3e-24 84.4 0.0 1.3e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 Y_phosphatase3 PF13350.1 KNZ79976.1 - 8e-29 100.9 0.0 1.5e-28 100.1 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KNZ79976.1 - 0.0025 17.1 0.0 0.0034 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Isy1 PF06246.7 KNZ79976.1 - 0.004 16.6 0.1 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 Isy1-like splicing family DSPc PF00782.15 KNZ79976.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.5 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain FLYWCH PF04500.11 KNZ79977.1 - 0.011 15.6 0.4 0.023 14.6 0.3 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain STT3 PF02516.9 KNZ79978.1 - 6.1e-58 196.9 12.7 1e-57 196.2 8.8 1.3 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit DDE_3 PF13358.1 KNZ79979.1 - 7.5e-05 22.5 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Kinetochor_Ybp2 PF08568.5 KNZ79980.1 - 4.8e-12 44.9 0.0 9.5e-08 30.7 0.0 2.3 2 1 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Pkinase PF00069.20 KNZ79981.1 - 1.1e-41 142.7 0.0 1.4e-28 99.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79981.1 - 1.2e-23 83.5 0.0 1.8e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ79981.1 - 0.00066 19.4 0.2 0.0012 18.6 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KNZ79981.1 - 0.0072 15.4 0.0 0.061 12.3 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family ExoD PF06055.7 KNZ79981.1 - 0.055 12.5 0.3 0.12 11.4 0.2 1.5 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Ifi-6-16 PF06140.8 KNZ79982.1 - 0.0002 21.0 23.1 0.00032 20.4 16.0 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family Ifi-6-16 PF06140.8 KNZ79983.1 - 0.024 14.3 28.2 0.058 13.1 18.9 1.9 1 1 1 2 2 2 0 Interferon-induced 6-16 family Yip1 PF04893.12 KNZ79983.1 - 2.1 7.8 14.9 4.6 6.7 10.4 1.6 1 1 0 1 1 1 0 Yip1 domain eIF-4B PF06273.6 KNZ79984.1 - 0.1 11.3 1.2 0.13 10.9 0.8 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B BAG PF02179.11 KNZ79985.1 - 0.0046 17.0 0.5 0.0082 16.2 0.0 1.7 2 0 0 2 2 2 1 BAG domain DUF1975 PF09318.5 KNZ79988.1 - 0.092 12.3 0.4 0.11 12.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1975) APH PF01636.18 KNZ79989.1 - 1.1e-12 48.1 0.7 8.5e-12 45.3 0.4 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ79989.1 - 4.9e-06 26.2 0.0 8.5e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KNZ79989.1 - 0.026 13.8 0.1 0.062 12.6 0.0 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KNZ79990.1 - 1.7e-13 50.8 0.4 6.4e-13 48.9 0.3 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ79990.1 - 2.7e-06 27.0 0.0 4.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KNZ79990.1 - 0.0085 15.4 0.1 0.056 12.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 KNZ79990.1 - 0.035 13.2 0.0 0.56 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Pheromone PF08015.6 KNZ79990.1 - 0.086 13.6 0.1 0.17 12.7 0.0 1.5 1 0 0 1 1 1 0 Fungal mating-type pheromone APH PF01636.18 KNZ79991.1 - 1.6e-13 50.9 0.2 5e-13 49.3 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ79991.1 - 2.6e-06 27.1 0.0 4.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KNZ79991.1 - 0.0088 15.4 0.1 0.056 12.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 KNZ79991.1 - 0.018 14.1 0.0 0.56 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Pheromone PF08015.6 KNZ79991.1 - 0.084 13.7 0.1 0.17 12.7 0.0 1.6 1 0 0 1 1 1 0 Fungal mating-type pheromone Stn1 PF10451.4 KNZ79993.1 - 3.8e-07 29.1 0.5 5.3e-06 25.4 0.1 2.4 2 1 0 2 2 2 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 KNZ79993.1 - 0.0028 17.4 0.7 0.0087 15.8 0.5 1.9 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain CH PF00307.26 KNZ79994.1 - 4.8e-67 222.8 0.0 6.5e-20 71.1 0.1 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KNZ79994.1 - 2.4e-06 27.1 0.0 1.3 8.7 0.0 4.4 4 0 0 4 4 4 3 CAMSAP CH domain Bestrophin PF01062.16 KNZ79995.1 - 2.4e-51 174.4 3.2 1.2e-30 106.4 0.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Pkinase PF00069.20 KNZ79996.1 - 2.9e-39 134.7 0.0 3.5e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ79996.1 - 3.9e-34 117.8 0.0 5.5e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ79996.1 - 0.035 13.0 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.12 KNZ79997.1 - 8.6e-11 41.3 0.1 1.1e-05 24.6 0.0 3.0 1 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KNZ79997.1 - 8.5e-05 21.8 0.1 0.055 12.6 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain APP_Cu_bd PF12924.2 KNZ79999.1 - 0.28 11.7 3.4 0.31 11.5 0.6 2.0 2 0 0 2 2 2 0 Copper-binding of amyloid precursor, CuBD p450 PF00067.17 KNZ80001.1 - 3.6e-67 226.9 0.0 5e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_15 PF01793.11 KNZ80002.1 - 2.5e-26 92.4 1.3 2.8e-26 92.2 0.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase p450 PF00067.17 KNZ80003.1 - 8.1e-40 136.7 0.0 3.2e-23 82.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 HTH_Tnp_Tc3_2 PF01498.13 KNZ80008.1 - 8.6e-05 22.5 1.8 0.00021 21.2 0.1 2.2 1 1 1 2 2 2 1 Transposase Trp_repressor PF01371.14 KNZ80008.1 - 0.00028 20.7 0.1 0.0005 19.9 0.1 1.3 1 0 0 1 1 1 1 Trp repressor protein HTH_29 PF13551.1 KNZ80008.1 - 0.00071 19.6 0.1 0.0014 18.7 0.0 1.6 1 1 0 1 1 1 1 Winged helix-turn helix F420_ligase PF01996.11 KNZ80008.1 - 0.031 13.3 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase Ubiq-Cytc-red_N PF09165.5 KNZ80008.1 - 0.086 13.1 0.2 0.28 11.5 0.0 1.9 2 1 0 2 2 2 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal PP-binding PF00550.20 KNZ80009.1 - 1.2e-10 41.4 0.6 1.7e-10 41.0 0.4 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KNZ80009.1 - 1.7e-06 27.9 0.2 2.3e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier Glyco_hydro_44 PF12891.2 KNZ80010.1 - 5.2e-45 153.8 3.1 8.5e-45 153.1 2.2 1.3 1 0 0 1 1 1 1 Glycoside hydrolase family 44 Glycos_transf_2 PF00535.21 KNZ80011.1 - 4.3e-31 107.8 0.0 5.9e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KNZ80011.1 - 9e-14 51.8 0.0 1.3e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KNZ80011.1 - 1.4e-08 34.2 0.0 1.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 KNZ80011.1 - 0.0086 16.3 0.0 0.039 14.2 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase family 2 F-box-like PF12937.2 KNZ80012.1 - 6.8e-09 35.3 0.2 1.2e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ80012.1 - 3e-06 26.7 0.1 5.2e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 F-box domain SMN PF06003.7 KNZ80013.1 - 0.015 14.4 0.4 0.015 14.4 0.3 3.0 2 1 1 3 3 3 0 Survival motor neuron protein (SMN) Pap_E4 PF02711.9 KNZ80013.1 - 0.51 11.1 8.5 0.11 13.3 2.3 2.2 2 0 0 2 2 2 0 E4 protein S-antigen PF05756.6 KNZ80013.1 - 2.9 7.9 7.6 2.8 7.9 0.5 2.3 2 0 0 2 2 2 0 S-antigen protein Nic96 PF04097.9 KNZ80014.1 - 2.4e-136 455.3 0.0 3.1e-136 455.0 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Usp PF00582.21 KNZ80014.1 - 0.72 10.0 4.2 3.6 7.7 0.0 3.0 3 0 0 3 3 3 0 Universal stress protein family Actin PF00022.14 KNZ80015.1 - 1.3e-47 162.1 0.0 3.8e-27 94.7 0.0 2.2 2 0 0 2 2 2 2 Actin DUF4192 PF13830.1 KNZ80015.1 - 6.1 6.3 8.6 11 5.5 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Ras PF00071.17 KNZ80016.1 - 4.3e-64 214.7 0.1 5.1e-64 214.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ80016.1 - 1.5e-19 70.6 0.0 2.4e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ80016.1 - 1.1e-13 50.8 0.1 1.4e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KNZ80016.1 - 6.9e-06 25.3 0.0 8.1e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KNZ80016.1 - 1.5e-05 24.5 0.1 5.4e-05 22.7 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KNZ80016.1 - 0.00024 21.0 0.0 0.00048 20.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KNZ80016.1 - 0.013 14.8 0.0 0.7 9.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 KNZ80016.1 - 0.033 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KNZ80016.1 - 0.036 14.0 0.1 0.051 13.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KNZ80016.1 - 0.045 13.8 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KNZ80016.1 - 0.061 12.5 0.0 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA PF00004.24 KNZ80016.1 - 0.077 13.2 0.0 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KNZ80016.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.5 KNZ80016.1 - 0.087 12.0 0.0 0.14 11.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 KNZ80016.1 - 0.094 11.7 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Septin UvrD_C PF13361.1 KNZ80017.1 - 2.8e-14 53.3 0.2 3.1e-10 40.0 0.0 3.6 4 0 0 4 4 4 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KNZ80017.1 - 2.3e-12 46.8 4.4 8.8e-11 41.6 0.4 3.0 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KNZ80017.1 - 3.2e-06 27.2 0.0 0.075 13.1 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 KNZ80017.1 - 1.4e-05 25.2 0.2 0.0042 17.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain TPR_7 PF13176.1 KNZ80017.1 - 0.062 13.1 0.6 34 4.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ80017.1 - 0.58 9.8 6.9 1.4 8.6 0.0 3.7 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.12 KNZ80017.1 - 8.7 6.5 13.2 11 6.1 0.3 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat DOT1 PF08123.8 KNZ80018.1 - 9.6e-62 207.9 0.0 1.2e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 KNZ80018.1 - 0.00015 22.3 0.0 0.00025 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ80018.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ABC_tran PF00005.22 KNZ80019.1 - 2.9e-27 95.6 0.0 3.1e-26 92.2 0.0 2.4 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KNZ80019.1 - 1.5e-13 51.4 0.1 2.2e-11 44.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KNZ80019.1 - 2.4e-08 33.4 0.0 0.0043 16.1 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KNZ80019.1 - 3.5e-05 23.1 0.0 0.024 13.8 0.1 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KNZ80019.1 - 0.00017 22.3 0.0 0.00048 20.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KNZ80019.1 - 0.00019 21.8 0.0 0.00036 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KNZ80019.1 - 0.00044 19.7 0.0 0.00095 18.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KNZ80019.1 - 0.00045 20.2 0.0 0.0019 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KNZ80019.1 - 0.001 18.7 0.0 0.003 17.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 KNZ80019.1 - 0.0025 17.4 0.0 0.24 11.0 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 KNZ80019.1 - 0.0045 17.1 0.0 0.035 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KNZ80019.1 - 0.0062 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.15 KNZ80019.1 - 0.0069 15.1 0.0 0.0093 14.6 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit DUF258 PF03193.11 KNZ80019.1 - 0.011 14.9 0.0 0.032 13.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KNZ80019.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KNZ80019.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 KNZ80019.1 - 0.024 14.5 0.0 0.064 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KNZ80019.1 - 0.035 13.5 0.0 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain MutS_V PF00488.16 KNZ80019.1 - 0.037 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 MutS domain V ATP-synt_ab PF00006.20 KNZ80019.1 - 0.042 13.3 0.0 2.7 7.4 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.1 KNZ80019.1 - 0.046 12.2 0.0 0.071 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KNZ80019.1 - 0.055 13.7 0.0 0.16 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 KNZ80019.1 - 0.058 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KNZ80019.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sel1 PF08238.7 KNZ80020.1 - 5.5e-20 71.3 12.5 6.7e-07 29.7 0.9 4.2 4 0 0 4 4 4 3 Sel1 repeat TPR_11 PF13414.1 KNZ80020.1 - 0.0019 17.8 1.8 0.35 10.5 0.2 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KNZ80020.1 - 0.0038 17.0 3.8 0.23 11.4 0.2 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ80020.1 - 0.0073 16.8 2.1 5.3 7.9 0.2 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ80020.1 - 0.018 15.6 1.6 0.13 12.9 0.2 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat HA2 PF04408.18 KNZ80021.1 - 2.5e-27 94.8 0.5 2e-26 91.9 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KNZ80021.1 - 3.5e-23 81.5 0.0 1.8e-22 79.2 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KNZ80021.1 - 6.5e-13 48.3 0.0 1.4e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KNZ80021.1 - 1e-08 34.8 0.1 2.6e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KNZ80021.1 - 1.1e-05 25.5 0.1 3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KNZ80021.1 - 0.00063 18.7 0.0 0.0013 17.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 KNZ80021.1 - 0.0016 18.3 0.0 2.5 7.8 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KNZ80021.1 - 0.0029 17.2 0.5 0.01 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KNZ80021.1 - 0.01 14.9 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 KNZ80021.1 - 0.014 15.2 0.1 0.093 12.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KNZ80021.1 - 0.023 13.6 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 KNZ80021.1 - 0.026 14.1 0.2 0.39 10.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 KNZ80021.1 - 0.028 14.1 0.4 0.13 11.9 0.0 2.3 3 0 0 3 3 2 0 Archaeal ATPase SRP54 PF00448.17 KNZ80021.1 - 0.034 13.5 0.1 0.081 12.3 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 KNZ80021.1 - 0.038 14.2 0.0 0.14 12.4 0.0 2.0 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 KNZ80021.1 - 0.04 12.7 0.1 0.071 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 KNZ80021.1 - 0.042 13.2 0.0 6 6.2 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain PhoH PF02562.11 KNZ80021.1 - 0.073 12.2 0.0 0.25 10.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Myosin_head PF00063.16 KNZ80021.1 - 0.093 10.7 0.0 0.16 10.0 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) Thiolase_N PF00108.18 KNZ80022.1 - 7.2e-08 31.7 0.0 8.8e-07 28.1 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KNZ80022.1 - 9e-06 25.1 0.4 4e-05 23.0 0.0 2.3 3 0 0 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KNZ80022.1 - 0.0011 18.5 0.0 0.14 11.8 0.0 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KNZ80022.1 - 0.0016 17.9 2.0 0.051 13.0 0.7 2.8 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SURF6 PF04935.7 KNZ80023.1 - 1.7e-35 122.2 44.5 1.7e-35 122.2 30.9 2.1 2 0 0 2 2 2 2 Surfeit locus protein 6 RRP14 PF15459.1 KNZ80023.1 - 3.4e-17 62.2 3.4 3.4e-17 62.2 2.4 4.3 3 1 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 RFC1 PF08519.7 KNZ80024.1 - 1.2e-45 155.0 0.1 2.4e-44 150.8 0.0 2.7 2 1 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KNZ80024.1 - 4.5e-14 52.3 0.0 1.4e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KNZ80024.1 - 2.4e-08 34.2 0.1 6.2e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KNZ80024.1 - 0.00043 19.9 0.0 0.0011 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KNZ80024.1 - 0.0015 17.3 0.4 0.02 13.6 0.1 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KNZ80024.1 - 0.0077 16.1 0.0 0.029 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KNZ80024.1 - 0.018 14.8 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KNZ80024.1 - 0.039 14.0 0.1 0.32 11.1 0.1 2.4 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KNZ80024.1 - 0.058 12.4 0.0 0.2 10.6 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 KNZ80024.1 - 0.073 12.7 0.5 0.32 10.6 0.2 2.1 1 1 0 2 2 2 0 NTPase NACHT PF05729.7 KNZ80024.1 - 0.087 12.4 0.1 8.2 6.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 KNZ80024.1 - 0.1 12.5 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 KNZ80024.1 - 0.11 12.4 0.7 0.49 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ribosomal_60s PF00428.14 KNZ80025.1 - 0.0046 17.3 4.7 0.0066 16.8 3.2 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein BSP_II PF05432.6 KNZ80025.1 - 0.0089 15.3 2.5 0.0099 15.1 1.8 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF3682 PF12446.3 KNZ80025.1 - 0.91 9.8 5.5 1.4 9.2 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) zf-RVT PF13966.1 KNZ80026.1 - 0.024 14.9 3.0 0.036 14.3 2.1 1.2 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Peptidase_M1 PF01433.15 KNZ80027.1 - 1.5e-60 205.3 0.0 2.1e-60 204.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KNZ80027.1 - 2.8e-29 101.5 0.1 1.1e-28 99.6 0.0 2.0 1 1 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KNZ80027.1 - 3.4e-13 49.7 0.1 6e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KNZ80027.1 - 0.046 13.7 2.4 0.71 9.8 1.7 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Proteasome PF00227.21 KNZ80028.1 - 8.2e-53 178.5 0.1 1.8e-52 177.3 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit adh_short PF00106.20 KNZ80028.1 - 1.8e-23 83.2 0.9 2.9e-23 82.5 0.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ80028.1 - 4.9e-21 75.6 0.1 2.3e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Proteasome_A_N PF10584.4 KNZ80028.1 - 2e-12 46.1 0.0 2e-12 46.1 0.0 2.8 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature KR PF08659.5 KNZ80028.1 - 8.8e-06 25.4 0.1 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KNZ80028.1 - 0.064 13.0 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 KNZ80028.1 - 0.13 11.9 1.4 0.16 11.6 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF962 PF06127.6 KNZ80029.1 - 2.1e-23 82.0 0.1 4e-23 81.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) BDV_P40 PF06407.6 KNZ80029.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Borna disease virus P40 protein TauE PF01925.14 KNZ80029.1 - 0.39 10.1 4.5 0.13 11.6 0.3 1.9 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE Longin PF13774.1 KNZ80030.1 - 3.5e-28 96.9 0.1 6.3e-28 96.1 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF4646 PF15496.1 KNZ80030.1 - 1.7e-15 57.1 0.2 2.4e-14 53.4 0.1 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Synaptobrevin PF00957.16 KNZ80030.1 - 9.6e-05 21.9 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin CDC45 PF02724.9 KNZ80030.1 - 0.21 9.6 3.5 0.36 8.8 2.4 1.3 1 0 0 1 1 1 0 CDC45-like protein XRN_N PF03159.13 KNZ80031.1 - 1.7e-55 187.9 5.8 9.9e-43 146.2 0.2 2.6 2 1 1 3 3 3 2 XRN 5'-3' exonuclease N-terminus DUF720 PF05302.6 KNZ80031.1 - 1.1 9.0 2.7 2 8.1 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF720) IF-2B PF01008.12 KNZ80032.1 - 9.8e-79 264.2 0.0 1.2e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family MTP18 PF10558.4 KNZ80033.1 - 4.3e-56 188.9 0.9 5.9e-56 188.5 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Fork_head PF00250.13 KNZ80034.1 - 8.1e-26 89.8 0.2 8.1e-26 89.8 0.1 1.8 2 0 0 2 2 2 1 Fork head domain FHA PF00498.21 KNZ80034.1 - 3.4e-06 27.0 0.0 6.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain IPK PF03770.11 KNZ80035.1 - 1.5e-53 181.4 0.0 2.4e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Myosin_tail_1 PF01576.14 KNZ80036.1 - 0.03 12.0 9.3 0.041 11.6 6.4 1.1 1 0 0 1 1 1 0 Myosin tail CENP-Q PF13094.1 KNZ80036.1 - 0.097 12.6 10.5 0.34 10.9 7.3 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 KNZ80036.1 - 0.6 9.6 8.2 1 8.9 5.7 1.3 1 0 0 1 1 1 0 IncA protein Med18 PF09637.5 KNZ80038.1 - 0.00011 21.7 0.0 0.0076 15.8 0.0 2.1 1 1 1 2 2 2 2 Med18 protein zf-HIT PF04438.11 KNZ80039.1 - 2.5e-05 23.8 13.5 3.5e-05 23.3 9.4 1.2 1 0 0 1 1 1 1 HIT zinc finger CIAPIN1 PF05093.8 KNZ80040.1 - 1.7e-29 101.8 4.3 2.9e-29 101.0 3.0 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Fork_head PF00250.13 KNZ80041.1 - 2.8e-30 104.2 0.0 4.6e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Fork head domain DUF3402 PF11882.3 KNZ80042.1 - 2.3e-128 428.7 0.0 3.4e-128 428.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KNZ80042.1 - 2.1e-49 167.9 0.0 3.7e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein Cyclin PF08613.6 KNZ80043.1 - 6.7e-08 33.0 0.0 1.4e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin ThiF PF00899.16 KNZ80044.1 - 2.4e-48 163.4 0.0 4.4e-28 97.7 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 KNZ80044.1 - 2.9e-45 153.4 0.1 7.3e-45 152.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 KNZ80044.1 - 1.3e-41 139.9 3.2 1.3e-27 95.0 0.1 3.5 4 0 0 4 4 4 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KNZ80044.1 - 8e-22 76.3 1.0 7.1e-19 66.9 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Cactin_mid PF10312.4 KNZ80045.1 - 1.1e-63 213.9 2.6 4.2e-63 212.0 1.8 2.1 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 KNZ80045.1 - 4e-58 194.4 5.3 9e-58 193.2 3.7 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein AAA_2 PF07724.9 KNZ80046.1 - 2e-34 118.9 0.0 1.2e-33 116.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KNZ80046.1 - 4.2e-12 46.4 0.0 1.5e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KNZ80046.1 - 3.5e-11 42.8 0.0 7.1e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_17 PF13207.1 KNZ80046.1 - 1.7e-05 25.6 0.0 3.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KNZ80046.1 - 2.8e-05 23.3 0.1 0.00074 18.7 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KNZ80046.1 - 6.2e-05 22.7 0.0 0.00014 21.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) T2SE PF00437.15 KNZ80046.1 - 0.00029 19.8 0.0 0.0005 19.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KNZ80046.1 - 0.0005 20.2 0.1 0.0027 17.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ80046.1 - 0.00067 19.6 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 KNZ80046.1 - 0.0017 18.0 0.0 0.024 14.3 0.0 2.5 3 0 0 3 3 2 1 Part of AAA domain IstB_IS21 PF01695.12 KNZ80046.1 - 0.0026 17.2 0.1 0.0052 16.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 KNZ80046.1 - 0.005 16.3 0.0 0.015 14.7 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain DEAD PF00270.24 KNZ80046.1 - 0.0077 15.7 0.1 0.03 13.7 0.0 1.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_33 PF13671.1 KNZ80046.1 - 0.0099 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KNZ80046.1 - 0.011 16.0 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 KNZ80046.1 - 0.012 15.8 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KNZ80046.1 - 0.015 14.9 0.0 0.058 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KNZ80046.1 - 0.018 14.2 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 KNZ80046.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.1 KNZ80046.1 - 0.023 14.7 0.0 0.081 12.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain HeH PF12949.2 KNZ80046.1 - 0.038 13.5 0.2 0.088 12.3 0.1 1.6 1 0 0 1 1 1 0 HeH/LEM domain AAA_10 PF12846.2 KNZ80046.1 - 0.046 13.1 0.1 0.094 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_3 PF07726.6 KNZ80046.1 - 0.054 13.1 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KNZ80046.1 - 0.061 12.3 0.1 0.26 10.2 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KNZ80046.1 - 0.072 13.2 0.0 0.23 11.6 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ResIII PF04851.10 KNZ80046.1 - 0.084 12.7 0.0 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.1 KNZ80046.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain UPF0079 PF02367.12 KNZ80046.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KNZ80046.1 - 0.12 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KNZ80046.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.9 KNZ80046.1 - 0.14 11.8 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MCM PF00493.18 KNZ80046.1 - 0.15 10.8 0.4 11 4.7 0.0 3.0 4 0 0 4 4 4 0 MCM2/3/5 family Ran_BP1 PF00638.13 KNZ80047.1 - 5.1e-32 110.4 0.3 7e-32 110.0 0.2 1.2 1 0 0 1 1 1 1 RanBP1 domain EMP24_GP25L PF01105.19 KNZ80048.1 - 4.2e-46 156.9 0.5 5e-46 156.7 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Kinesin PF00225.18 KNZ80049.1 - 3.8e-88 295.4 0.0 7.4e-88 294.4 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain DivIC PF04977.10 KNZ80049.1 - 0.18 11.2 2.3 7.6 6.0 1.6 2.9 2 0 0 2 2 2 0 Septum formation initiator Amidohydro_2 PF04909.9 KNZ80050.1 - 9.2e-08 31.9 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KNZ80050.1 - 2.9e-06 27.5 0.1 3.9e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase Glyco_hydro_76 PF03663.9 KNZ80051.1 - 0.12 11.7 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 DUF3734 PF12536.3 KNZ80052.1 - 0.083 13.0 0.2 0.098 12.7 0.1 1.2 1 0 0 1 1 1 0 Patatin phospholipase zf-RVT PF13966.1 KNZ80053.1 - 0.084 13.1 1.4 0.19 12.0 0.9 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase 2-Hacid_dh_C PF02826.14 KNZ80053.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GAS2 PF02187.12 KNZ80054.1 - 1.1e-07 31.4 0.0 2.8e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Iso_dh PF00180.15 KNZ80056.1 - 5.4e-99 331.4 0.0 6.2e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WD40 PF00400.27 KNZ80057.1 - 2.4e-30 103.3 9.6 7.2e-11 41.5 1.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat NmrA PF05368.8 KNZ80058.1 - 4.4e-10 39.2 0.0 7e-10 38.5 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KNZ80058.1 - 6.3e-05 23.0 0.2 0.00018 21.6 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KNZ80058.1 - 0.011 15.2 0.0 0.034 13.5 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 KNZ80058.1 - 0.016 15.4 0.0 0.04 14.1 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.13 KNZ80058.1 - 0.032 14.2 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.5 KNZ80058.1 - 0.052 13.2 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 KR domain UDPG_MGDP_dh_N PF03721.9 KNZ80058.1 - 0.13 11.6 3.4 0.42 9.9 0.5 2.1 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 KNZ80058.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Arf PF00025.16 KNZ80059.1 - 6.9e-72 240.3 0.0 8.2e-72 240.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KNZ80059.1 - 2.2e-15 56.3 0.0 3e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KNZ80059.1 - 1.9e-14 53.1 0.3 5.1e-09 35.3 0.0 2.3 2 1 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KNZ80059.1 - 7e-11 41.7 0.0 8.7e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KNZ80059.1 - 2.7e-10 39.8 0.0 3.1e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ80059.1 - 6.8e-09 36.2 0.0 9e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KNZ80059.1 - 0.00017 21.5 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KNZ80059.1 - 0.016 14.6 0.0 0.092 12.1 0.0 1.9 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF2373 PF10180.4 KNZ80060.1 - 8.1e-16 57.3 0.1 1.2e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) cwf21 PF08312.7 KNZ80061.1 - 9e-16 57.4 8.5 9e-16 57.4 5.9 2.3 2 0 0 2 2 2 1 cwf21 domain Hom_end_hint PF05203.11 KNZ80061.1 - 0.033 13.9 0.7 0.048 13.3 0.5 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint CHD5 PF04420.9 KNZ80061.1 - 7.9 6.1 5.6 15 5.2 3.9 1.4 1 0 0 1 1 1 0 CHD5-like protein DUF4169 PF13770.1 KNZ80061.1 - 8.7 6.3 14.2 20 5.2 9.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4169) Abhydrolase_6 PF12697.2 KNZ80062.1 - 9.2e-32 110.7 0.0 1.3e-31 110.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ80062.1 - 1.9e-18 66.8 0.0 1.2e-14 54.4 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ80062.1 - 9.9e-15 54.5 0.0 9.9e-10 38.3 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KNZ80062.1 - 0.00022 20.8 0.1 0.0096 15.5 0.0 2.7 2 1 1 3 3 3 1 alpha/beta hydrolase fold Esterase PF00756.15 KNZ80062.1 - 0.00029 20.3 0.0 0.0007 19.0 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.9 KNZ80062.1 - 0.00086 17.8 0.0 0.0021 16.6 0.0 1.5 2 0 0 2 2 2 1 Ndr family Hydrolase_4 PF12146.3 KNZ80062.1 - 0.0012 18.6 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 KNZ80062.1 - 0.0017 17.7 0.0 0.0049 16.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 KNZ80062.1 - 0.0032 17.0 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase BAAT_C PF08840.6 KNZ80062.1 - 0.0038 16.9 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.6 KNZ80062.1 - 0.028 13.5 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.11 KNZ80062.1 - 0.083 12.3 0.0 16 4.8 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase UPF0227 PF05728.7 KNZ80062.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) MT-A70 PF05063.9 KNZ80063.1 - 3.1e-52 176.6 0.1 4.3e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 MT-A70 MpPF26 PF07666.6 KNZ80066.1 - 7.9 6.3 19.8 0.2 11.5 7.7 2.2 2 0 0 2 2 2 0 M penetrans paralogue family 26 Acetyltransf_2 PF00797.12 KNZ80067.1 - 1.5e-29 103.3 0.0 3.1e-29 102.2 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase CAP59_mtransfer PF11735.3 KNZ80068.1 - 2.1e-71 239.9 0.1 2.7e-71 239.6 0.1 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ion_trans PF00520.26 KNZ80068.1 - 0.056 12.6 0.1 0.16 11.1 0.0 1.6 1 1 1 2 2 2 0 Ion transport protein Acetyltransf_2 PF00797.12 KNZ80072.1 - 2.8e-19 69.6 0.0 3.5e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase TPR_12 PF13424.1 KNZ80074.1 - 2e-09 37.2 10.3 5.6e-05 22.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ80074.1 - 8.3e-08 31.5 10.9 0.16 11.9 0.1 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat AAA_22 PF13401.1 KNZ80074.1 - 1.6e-07 31.5 0.1 7.5e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KNZ80074.1 - 2.5e-07 29.8 0.0 2.6e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain TPR_1 PF00515.23 KNZ80074.1 - 1.8e-05 24.1 3.8 3.9 7.2 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ80074.1 - 0.00012 21.5 17.3 0.012 15.3 0.2 5.8 7 0 0 7 7 5 2 Tetratricopeptide repeat AAA_16 PF13191.1 KNZ80074.1 - 0.00021 21.3 0.5 0.0017 18.3 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain TPR_14 PF13428.1 KNZ80074.1 - 0.0003 21.1 3.4 4.8 8.0 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat AAA PF00004.24 KNZ80074.1 - 0.0015 18.7 1.8 0.0038 17.4 0.0 2.6 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) TPR_11 PF13414.1 KNZ80074.1 - 0.012 15.2 0.2 0.012 15.2 0.2 3.9 5 0 0 5 5 5 0 TPR repeat Apc5 PF12862.2 KNZ80074.1 - 0.016 15.0 0.8 0.058 13.2 0.6 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 DUF258 PF03193.11 KNZ80074.1 - 0.096 11.8 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RPN7 PF10602.4 KNZ80074.1 - 0.11 11.8 2.7 9.2 5.6 0.2 3.8 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_16 PF13432.1 KNZ80074.1 - 0.13 12.9 12.5 10 6.9 0.2 5.1 3 2 1 4 4 4 0 Tetratricopeptide repeat EFG_C PF00679.19 KNZ80075.1 - 1.6e-15 56.7 0.0 2.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KNZ80075.1 - 0.0014 18.7 0.1 0.0032 17.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Aldedh PF00171.17 KNZ80076.1 - 5.3e-27 94.2 0.1 6.1e-27 94.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Chorion_2 PF03964.10 KNZ80076.1 - 0.08 13.4 0.3 0.12 12.9 0.2 1.4 1 1 0 1 1 1 0 Chorion family 2 AAA_22 PF13401.1 KNZ80077.1 - 7.9e-09 35.7 0.0 3.6e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KNZ80077.1 - 9.3e-07 27.9 0.0 1.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KNZ80077.1 - 8.2e-06 25.9 0.2 7.4e-05 22.8 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.24 KNZ80077.1 - 0.0025 18.0 0.0 0.0075 16.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Homoserine_dh PF00742.14 KNZ80077.1 - 0.019 14.6 0.1 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Homoserine dehydrogenase AAA_24 PF13479.1 KNZ80077.1 - 0.02 14.5 0.3 0.35 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KNZ80077.1 - 0.024 13.8 0.0 0.055 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 KNZ80077.1 - 0.044 13.2 0.0 0.33 10.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 KNZ80077.1 - 0.061 13.3 0.0 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 KNZ80077.1 - 0.079 11.8 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 KNZ80077.1 - 0.094 13.0 0.6 0.43 10.8 0.0 2.4 3 1 0 3 3 3 0 ABC transporter EFG_C PF00679.19 KNZ80078.1 - 2.8e-09 36.7 0.0 5.4e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KNZ80078.1 - 0.072 13.2 0.5 0.2 11.8 0.3 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Aldedh PF00171.17 KNZ80079.1 - 2.4e-17 62.4 0.1 2.5e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NAD_binding_4 PF07993.7 KNZ80080.1 - 0.00068 18.6 0.0 0.014 14.3 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Pkinase PF00069.20 KNZ80081.1 - 1.1e-16 60.7 0.2 8.5e-10 38.2 0.1 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ80081.1 - 0.018 14.1 0.2 0.037 13.1 0.1 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Asp_protease_2 PF13650.1 KNZ80083.1 - 0.002 18.5 0.0 0.0044 17.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Endonuc-HincII PF09226.6 KNZ80085.1 - 0.035 13.4 1.5 0.037 13.3 1.0 1.0 1 0 0 1 1 1 0 Restriction endonuclease HincII ArsC PF03960.10 KNZ80085.1 - 0.056 13.5 0.9 0.063 13.3 0.7 1.1 1 0 0 1 1 1 0 ArsC family DUF1390 PF07150.6 KNZ80085.1 - 0.73 9.1 4.5 0.71 9.1 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) Mem_trans PF03547.13 KNZ80086.1 - 1.1e-43 149.0 0.1 2.4e-38 131.4 0.0 2.3 2 1 0 2 2 2 2 Membrane transport protein YhhN PF07947.9 KNZ80086.1 - 0.0021 17.4 3.3 0.0084 15.5 2.3 2.0 1 0 0 1 1 1 1 YhhN-like protein PCMT PF01135.14 KNZ80087.1 - 1e-68 231.0 0.0 1.2e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KNZ80087.1 - 2.3e-07 31.4 0.0 3.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ80087.1 - 2.8e-06 26.9 0.0 3.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ80087.1 - 1.1e-05 25.4 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 KNZ80087.1 - 3.8e-05 23.2 0.0 5.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_23 PF13489.1 KNZ80087.1 - 7.4e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ80087.1 - 0.0017 18.7 0.0 0.0038 17.6 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KNZ80087.1 - 0.0021 17.7 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNZ80087.1 - 0.005 15.9 0.0 0.0069 15.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 KNZ80087.1 - 0.018 14.3 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.9 KNZ80087.1 - 0.036 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KNZ80087.1 - 0.037 13.1 0.0 0.095 11.8 0.0 1.7 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 KNZ80087.1 - 0.07 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 KNZ80087.1 - 0.076 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Fibrillarin PF01269.12 KNZ80087.1 - 0.11 11.4 0.1 0.19 10.6 0.1 1.3 1 0 0 1 1 1 0 Fibrillarin EF-hand_1 PF00036.27 KNZ80087.1 - 0.16 11.3 0.0 0.48 9.8 0.0 1.7 1 0 0 1 1 1 0 EF hand Chromo PF00385.19 KNZ80089.1 - 0.006 16.2 0.1 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 KNZ80089.1 - 0.0074 15.6 0.2 0.0094 15.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 KNZ80090.1 - 0.11 12.0 0.2 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease Oxidored_FMN PF00724.15 KNZ80092.1 - 1.1e-72 244.8 0.0 1.5e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 KNZ80092.1 - 0.14 10.9 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 KNZ80093.1 - 1.3e-37 129.6 0.0 1.7e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family LRR_6 PF13516.1 KNZ80094.1 - 7.8e-09 34.7 11.7 0.2 11.8 0.2 6.3 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 KNZ80094.1 - 0.095 12.3 9.4 0.12 12.0 0.6 3.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Glyco_hydro_53 PF07745.8 KNZ80095.1 - 5.6e-81 271.8 0.0 5.2e-80 268.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.13 KNZ80095.1 - 0.0007 18.8 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MHC_I_2 PF14586.1 KNZ80095.1 - 0.0037 16.8 0.0 0.007 15.9 0.0 1.4 1 0 0 1 1 1 1 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 zf-RING_2 PF13639.1 KNZ80097.1 - 1e-11 44.4 4.3 2.3e-11 43.3 3.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KNZ80097.1 - 6.3e-11 42.2 0.6 1.4e-10 41.1 0.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KNZ80097.1 - 2.2e-06 27.5 3.9 4.5e-06 26.5 2.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNZ80097.1 - 2.5e-06 27.0 2.7 4.5e-06 26.2 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ80097.1 - 1.8e-05 24.3 3.4 3.7e-05 23.3 2.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KNZ80097.1 - 3.3e-05 23.4 1.9 6.5e-05 22.5 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KNZ80097.1 - 0.0011 18.8 4.4 0.0041 16.9 3.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KNZ80097.1 - 0.0051 16.7 2.5 0.012 15.5 1.7 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 KNZ80097.1 - 0.21 11.6 4.2 0.41 10.7 2.9 1.5 1 0 0 1 1 1 0 RING-variant domain Sec23_trunk PF04811.10 KNZ80098.1 - 2.2e-77 259.6 0.0 3.7e-77 258.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KNZ80098.1 - 8.1e-35 118.3 0.5 1.6e-34 117.3 0.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KNZ80098.1 - 7.3e-30 103.3 0.3 1.6e-29 102.2 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KNZ80098.1 - 9e-17 60.3 6.3 1.6e-16 59.5 4.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KNZ80098.1 - 8.4e-13 47.8 0.0 4.2e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat Cnd3 PF12719.2 KNZ80100.1 - 2e-81 273.2 2.6 6.4e-81 271.6 1.8 1.9 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KNZ80100.1 - 0.00018 21.7 3.7 0.0027 17.9 0.1 4.2 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 KNZ80100.1 - 0.00021 21.1 0.4 3.1 8.1 0.1 4.4 3 0 0 3 3 3 2 HEAT repeat DUF1770 PF08589.5 KNZ80101.1 - 4.7e-09 36.7 0.1 6.7e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) p450 PF00067.17 KNZ80104.1 - 9.4e-74 248.5 0.0 3.3e-73 246.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 GST_N_2 PF13409.1 KNZ80106.1 - 1.4e-23 82.6 0.2 2.4e-22 78.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KNZ80106.1 - 5.2e-15 55.0 0.2 1.3e-14 53.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KNZ80106.1 - 5.7e-11 42.2 0.0 1.1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KNZ80106.1 - 5.8e-05 23.2 0.2 0.001 19.2 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KNZ80106.1 - 0.00012 22.4 0.0 0.0002 21.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Nup96 PF12110.3 KNZ80108.1 - 5.3e-69 232.5 0.0 7.2e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Glyco_hydro_16 PF00722.16 KNZ80109.1 - 4e-09 36.0 0.0 8.1e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 UQ_con PF00179.21 KNZ80111.1 - 1.4e-47 160.5 0.0 1.6e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KNZ80111.1 - 0.00012 21.8 0.0 0.00012 21.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KNZ80111.1 - 0.0014 18.4 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KNZ80111.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain OPT PF03169.10 KNZ80112.1 - 1.3e-88 298.0 39.2 1.8e-88 297.5 27.2 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PWI PF01480.12 KNZ80113.1 - 3.7e-28 97.4 0.0 6e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 PWI domain EMP24_GP25L PF01105.19 KNZ80114.1 - 8.9e-40 136.3 0.0 1e-39 136.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Laminin_II PF06009.7 KNZ80114.1 - 0.077 12.7 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain II Dak1 PF02733.12 KNZ80115.1 - 1.5e-104 349.1 0.5 2.1e-104 348.6 0.3 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KNZ80115.1 - 9.9e-41 139.3 2.0 1.6e-40 138.6 1.4 1.3 1 0 0 1 1 1 1 DAK2 domain Peptidase_M20 PF01546.23 KNZ80115.1 - 0.21 11.0 2.4 0.42 10.0 0.3 2.2 1 1 1 2 2 2 0 Peptidase family M20/M25/M40 UCH PF00443.24 KNZ80116.1 - 9.2e-80 267.6 0.0 1.4e-79 266.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNZ80116.1 - 4.2e-19 69.0 0.0 1.6e-12 47.4 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KNZ80116.1 - 4.5e-16 59.0 0.1 1.8e-15 57.1 0.0 2.1 1 0 0 1 1 1 1 DUSP domain Zn-ribbon_8 PF09723.5 KNZ80116.1 - 3 7.8 8.8 0.33 10.9 0.6 2.6 3 0 0 3 3 3 0 Zinc ribbon domain Sugar_tr PF00083.19 KNZ80117.1 - 1e-132 442.9 22.4 1.2e-132 442.7 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ80117.1 - 1.3e-23 83.2 56.1 5.1e-22 78.0 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KNZ80117.1 - 3.2 5.7 14.6 0.18 9.9 3.5 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Cyto_heme_lyase PF01265.12 KNZ80118.1 - 1.9e-64 217.7 1.1 2.2e-64 217.5 0.7 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Tim44 PF04280.10 KNZ80119.1 - 5.7e-30 104.2 0.5 5.7e-30 104.2 0.4 1.9 2 0 0 2 2 2 1 Tim44-like domain Ribosomal_S20p PF01649.13 KNZ80119.1 - 0.1 12.9 2.8 0.11 12.8 0.2 2.4 2 0 0 2 2 2 0 Ribosomal protein S20 DMPK_coil PF08826.5 KNZ80119.1 - 0.2 11.5 5.7 0.26 11.1 0.3 2.9 1 1 1 2 2 2 0 DMPK coiled coil domain like DUF3813 PF12758.2 KNZ80119.1 - 5.3 7.2 8.3 15 5.8 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3813) PIG-P PF08510.7 KNZ80120.1 - 0.023 14.3 4.4 0.33 10.5 0.2 2.4 2 0 0 2 2 2 0 PIG-P Herpes_UL45 PF05473.7 KNZ80120.1 - 1.9 7.8 7.9 5.6 6.3 0.8 2.2 2 0 0 2 2 2 0 UL45 protein p450 PF00067.17 KNZ80121.1 - 3.2e-56 190.7 0.0 4.2e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF482 PF04339.7 KNZ80121.1 - 0.16 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF482 PIF1 PF05970.9 KNZ80122.1 - 7.3e-61 206.1 1.8 9.4e-48 162.9 0.2 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KNZ80122.1 - 2.9e-16 59.6 0.0 5.7e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 KNZ80122.1 - 1.1e-07 30.1 0.3 4.8e-06 24.6 0.0 2.3 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.1 KNZ80122.1 - 2.7e-06 27.5 0.1 6.9e-06 26.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain UvrD_C_2 PF13538.1 KNZ80122.1 - 7.2e-05 22.8 0.0 0.00049 20.2 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KNZ80122.1 - 8.9e-05 22.1 0.3 0.00023 20.8 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KNZ80122.1 - 0.00049 19.6 0.5 0.5 9.8 0.2 3.1 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KNZ80122.1 - 0.00074 19.5 0.1 0.0017 18.4 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.24 KNZ80122.1 - 0.0016 18.6 0.3 0.0091 16.2 0.1 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KNZ80122.1 - 0.007 15.3 2.1 0.046 12.6 0.1 2.7 3 1 1 4 4 4 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KNZ80122.1 - 0.007 15.6 0.0 0.029 13.5 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.12 KNZ80122.1 - 0.0092 15.4 0.0 2.9 7.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 KNZ80122.1 - 0.013 15.2 0.8 0.11 12.2 0.5 2.1 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 KNZ80122.1 - 0.015 15.1 0.0 0.085 12.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KNZ80122.1 - 0.016 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 KNZ80122.1 - 0.017 14.8 1.1 0.49 10.1 0.2 3.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 KNZ80122.1 - 0.021 13.4 0.0 0.032 12.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 KNZ80122.1 - 0.038 12.8 0.0 0.095 11.5 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_11 PF13086.1 KNZ80122.1 - 0.039 13.5 0.3 6.8 6.1 0.0 2.6 1 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KNZ80122.1 - 0.043 13.5 0.1 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_32 PF13654.1 KNZ80122.1 - 0.063 11.9 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KNZ80122.1 - 0.064 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 KNZ80122.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 KNZ80122.1 - 0.065 12.5 0.9 0.12 11.6 0.2 1.7 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain ABC_tran PF00005.22 KNZ80122.1 - 0.076 13.3 0.2 0.6 10.4 0.1 2.4 2 1 0 3 3 3 0 ABC transporter RNA_helicase PF00910.17 KNZ80122.1 - 0.12 12.5 0.0 0.39 10.9 0.0 1.9 1 1 0 1 1 1 0 RNA helicase COesterase PF00135.23 KNZ80123.1 - 4.1e-88 296.4 0.0 4.8e-88 296.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ80123.1 - 4.5e-10 39.4 0.1 1.3e-09 37.9 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ80123.1 - 0.0011 18.7 0.6 0.0016 18.2 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ80123.1 - 0.02 14.1 0.1 0.032 13.4 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2424 PF10340.4 KNZ80123.1 - 0.22 10.1 0.0 8.8 4.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) WEMBL PF05701.6 KNZ80124.1 - 0.023 13.1 1.1 0.031 12.7 0.8 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light GvpH PF05455.6 KNZ80124.1 - 0.086 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 GvpH DUF1295 PF06966.7 KNZ80125.1 - 3.1e-38 131.3 10.0 2.1e-36 125.4 6.9 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KNZ80125.1 - 0.0045 17.0 0.0 0.0045 17.0 0.0 2.6 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 KNZ80125.1 - 0.021 15.0 0.0 0.021 15.0 0.0 2.2 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PYC_OADA PF02436.13 KNZ80126.1 - 2.2 7.6 6.3 3 7.2 3.9 1.5 1 1 0 1 1 1 0 Conserved carboxylase domain Rcd1 PF04078.8 KNZ80127.1 - 3.4e-121 403.0 1.2 4.6e-121 402.6 0.9 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like FA_hydroxylase PF04116.8 KNZ80128.1 - 1.3e-19 70.6 7.3 1.3e-19 70.6 5.1 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3561 PF12084.3 KNZ80128.1 - 2.2 8.1 8.6 1.1 9.1 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) Ribosomal_L28e PF01778.12 KNZ80129.1 - 2.2e-25 89.3 0.4 2.2e-25 89.3 0.3 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 KNZ80129.1 - 8.5e-19 67.5 25.7 8.5e-19 67.5 17.8 3.2 2 1 0 2 2 2 1 Mak16 protein C-terminal region RVT_1 PF00078.22 KNZ80129.1 - 8.8e-05 21.9 1.7 0.00016 21.1 0.2 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2457 PF10446.4 KNZ80129.1 - 0.42 9.2 16.2 0.6 8.7 11.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIA PF03153.8 KNZ80129.1 - 0.88 9.3 20.0 1.7 8.4 13.8 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 KNZ80129.1 - 5.3 4.8 24.6 7.7 4.2 17.0 1.2 1 0 0 1 1 1 0 Nop14-like family AMP-binding PF00501.23 KNZ80130.1 - 5.4e-95 318.2 0.7 6.9e-95 317.8 0.1 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 KNZ80130.1 - 6e-22 78.3 0.1 1.2e-20 74.2 0.1 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Retrotrans_gag PF03732.12 KNZ80131.1 - 0.025 14.6 0.4 0.055 13.5 0.2 1.6 1 1 1 2 2 2 0 Retrotransposon gag protein DUF972 PF06156.8 KNZ80132.1 - 0.0071 16.6 4.8 1.2 9.5 1.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF972) ATG16 PF08614.6 KNZ80132.1 - 0.015 15.1 8.2 0.082 12.7 2.6 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF3166 PF11365.3 KNZ80132.1 - 0.029 14.8 1.3 0.14 12.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) Fusion_gly PF00523.13 KNZ80132.1 - 0.075 11.0 0.1 0.15 10.1 0.1 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 CheB_methylest PF01339.12 KNZ80132.1 - 0.075 12.4 0.4 0.24 10.7 0.3 1.8 2 0 0 2 2 2 0 CheB methylesterase Sirohm_synth_C PF14823.1 KNZ80132.1 - 0.13 11.5 0.1 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal Spc7 PF08317.6 KNZ80132.1 - 0.16 10.5 10.6 0.5 8.9 0.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 KNZ80132.1 - 0.18 11.3 9.8 0.49 9.9 3.3 2.2 2 0 0 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 KNZ80132.1 - 0.21 11.3 10.2 0.46 10.2 0.2 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4618 PF15397.1 KNZ80132.1 - 0.21 10.8 7.8 0.099 11.9 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Sec8_exocyst PF04048.9 KNZ80132.1 - 0.31 10.6 5.4 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Uds1 PF15456.1 KNZ80132.1 - 0.33 10.9 8.4 2.7 8.0 0.1 2.5 2 0 0 2 2 2 0 Up-regulated During Septation RraB PF06877.6 KNZ80132.1 - 0.34 11.5 5.0 0.082 13.5 1.1 1.7 2 0 0 2 2 1 0 Regulator of ribonuclease activity B DUF812 PF05667.6 KNZ80132.1 - 0.85 8.0 7.7 0.76 8.2 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) FH2 PF02181.18 KNZ80132.1 - 1 8.1 6.8 0.59 8.9 0.2 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain CENP-F_leu_zip PF10473.4 KNZ80132.1 - 2.1 8.1 14.1 2.5 7.9 3.9 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 KNZ80132.1 - 2.6 7.5 10.6 2.9 7.4 0.5 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fungal_trans PF04082.13 KNZ80133.1 - 1.4e-22 79.7 1.6 3.5e-22 78.5 1.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ80133.1 - 1.6e-05 24.6 10.1 2.8e-05 23.9 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cation_efflux PF01545.16 KNZ80134.1 - 8.3e-46 156.3 7.1 8.3e-46 156.3 4.9 2.8 2 1 0 2 2 2 1 Cation efflux family Zip PF02535.17 KNZ80134.1 - 0.0044 16.0 12.3 0.0044 16.0 8.5 3.5 1 1 2 3 3 3 2 ZIP Zinc transporter CASP_C PF08172.7 KNZ80134.1 - 0.006 15.6 0.7 0.013 14.4 0.5 1.5 1 0 0 1 1 1 1 CASP C terminal Fungal_trans PF04082.13 KNZ80135.1 - 9.9e-05 21.3 0.2 0.00038 19.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ80135.1 - 1.3 9.0 8.2 2.2 8.2 5.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PDCD2_C PF04194.8 KNZ80136.1 - 2.9e-30 105.0 0.7 6.6e-30 103.8 0.0 1.9 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain PTRF_SDPR PF15237.1 KNZ80136.1 - 0.0095 15.3 0.2 0.015 14.7 0.2 1.2 1 0 0 1 1 1 1 PTRF/SDPR family Hexokinase_2 PF03727.11 KNZ80137.1 - 3.1e-80 268.8 0.0 4.4e-80 268.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KNZ80137.1 - 1.4e-69 233.5 0.0 2e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 KNZ80137.1 - 0.12 11.7 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Helitron_like_N PF14214.1 KNZ80138.1 - 5e-63 212.1 0.3 1.1e-62 211.0 0.1 1.6 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 KNZ80138.1 - 0.061 12.0 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) DUF3296 PF11726.3 KNZ80138.1 - 0.093 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) Pkinase PF00069.20 KNZ80139.1 - 2.9e-27 95.4 0.0 3.5e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ80139.1 - 5e-09 35.6 0.0 6.4e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ80139.1 - 4.2e-05 22.6 0.0 5.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KNZ80139.1 - 0.093 12.2 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Frag1 PF10277.4 KNZ80139.1 - 1.3 8.4 5.8 0.075 12.5 0.6 1.5 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family RVP_2 PF08284.6 KNZ80142.1 - 0.13 12.1 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Pkinase_Tyr PF07714.12 KNZ80144.1 - 4.2e-57 193.1 0.0 6.8e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ80144.1 - 4e-48 163.8 0.0 7.5e-48 162.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KNZ80144.1 - 0.0011 18.0 0.1 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Arm PF00514.18 KNZ80144.1 - 0.0067 16.2 5.2 2.2 8.2 0.0 3.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat RIO1 PF01163.17 KNZ80144.1 - 0.044 13.1 0.1 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KNZ80144.1 - 0.077 12.7 0.2 0.33 10.6 0.0 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KNZ80144.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like zf-RING_5 PF14634.1 KNZ80145.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 KNZ80145.1 - 0.058 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Ring finger domain Mito_fiss_reg PF05308.6 KNZ80145.1 - 0.61 9.4 13.6 0.14 11.5 0.3 3.0 3 0 0 3 3 3 0 Mitochondrial fission regulator DUF1996 PF09362.5 KNZ80147.1 - 5.2e-66 222.6 0.5 7.7e-66 222.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RGS PF00615.14 KNZ80148.1 - 1.4e-19 70.3 1.0 3.2e-19 69.1 0.7 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 KNZ80148.1 - 7.3e-09 35.2 0.1 0.0017 18.0 0.0 2.5 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RF-1 PF00472.15 KNZ80149.1 - 2.4e-17 62.7 0.7 3.5e-17 62.2 0.5 1.2 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 KNZ80149.1 - 0.00035 20.6 0.4 0.00062 19.8 0.2 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit protein Arrestin_N PF00339.24 KNZ80151.1 - 4e-05 23.4 0.8 9.4e-05 22.2 0.0 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ABC2_membrane PF01061.19 KNZ80152.1 - 3.7e-23 81.7 21.1 5.7e-23 81.1 14.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KNZ80152.1 - 0.00042 20.6 0.0 0.0067 16.7 0.0 2.2 2 0 0 2 2 2 1 ABC transporter COX6B PF02297.12 KNZ80154.1 - 5.7e-22 77.5 4.3 7.2e-22 77.1 3.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 KNZ80154.1 - 0.0026 17.7 0.9 0.0032 17.4 0.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.11 KNZ80154.1 - 0.49 10.3 3.0 2.1 8.3 1.9 1.9 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein FAD_binding_4 PF01565.18 KNZ80155.1 - 3.2e-20 72.0 0.8 7.2e-20 70.8 0.5 1.6 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 KNZ80155.1 - 0.00074 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 KNZ80156.1 - 9.2e-12 44.3 26.8 5.2e-06 25.4 9.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ80156.1 - 1.4e-11 43.6 17.0 1.2e-10 40.5 11.8 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter DDE_1 PF03184.14 KNZ80156.1 - 1e-10 41.1 0.0 1.8e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CK_II_beta PF01214.13 KNZ80157.1 - 2e-71 239.2 0.0 2.6e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CDK2AP PF09806.4 KNZ80157.1 - 0.03 14.5 0.0 0.047 13.9 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein RabGAP-TBC PF00566.13 KNZ80158.1 - 2.5e-48 164.3 0.0 4e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MAT1 PF06391.8 KNZ80158.1 - 0.04 13.4 0.9 0.088 12.3 0.6 1.5 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Lipase_3 PF01764.20 KNZ80159.1 - 5.2e-31 107.1 0.0 7.4e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 KNZ80159.1 - 0.0023 17.3 0.0 0.0065 15.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 KNZ80159.1 - 0.0063 16.4 0.1 0.0077 16.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ80159.1 - 0.0077 15.9 0.1 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KNZ80159.1 - 0.059 12.9 0.1 0.087 12.3 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.8 KNZ80159.1 - 0.081 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chromo PF00385.19 KNZ80161.1 - 3.2e-15 55.5 0.2 3.9e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 KNZ80162.1 - 5.9e-05 23.4 0.0 0.00068 20.0 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.6 KNZ80162.1 - 0.00057 19.8 0.1 0.16 11.9 0.0 2.9 1 1 2 3 3 3 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KNZ80162.1 - 0.0011 18.7 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Sdh_cyt PF01127.17 KNZ80164.1 - 3.5e-25 88.1 1.0 4.5e-25 87.8 0.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF544 PF04424.8 KNZ80165.1 - 3.5e-17 62.3 0.0 8.6e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF3801 PF12687.2 KNZ80165.1 - 0.00032 20.3 0.2 0.00036 20.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3801) Cadherin_2 PF08266.7 KNZ80165.1 - 0.41 10.2 3.3 0.72 9.4 2.3 1.3 1 0 0 1 1 1 0 Cadherin-like RNase_P_Rpp14 PF01900.14 KNZ80166.1 - 2.5e-27 94.9 0.0 3e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family DUF4139 PF13598.1 KNZ80167.1 - 4.1e-61 207.0 8.0 1.4e-40 139.5 3.1 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KNZ80167.1 - 1.4e-12 47.9 1.9 1.6e-12 47.7 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.1 KNZ80167.1 - 0.031 14.5 9.7 0.13 12.5 6.8 1.9 1 1 0 1 1 1 0 Nucleoporin FG repeat region FmdA_AmdA PF03069.10 KNZ80168.1 - 5.5e-138 459.6 0.0 6.7e-138 459.3 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family SET PF00856.23 KNZ80169.1 - 5.5e-12 46.2 0.0 3.5e-10 40.4 0.0 2.5 1 1 0 1 1 1 1 SET domain Ribosomal_S7 PF00177.16 KNZ80170.1 - 4.8e-26 91.1 0.1 5.5e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e TPR_11 PF13414.1 KNZ80172.1 - 1.7e-20 72.4 4.3 6.5e-15 54.5 1.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KNZ80172.1 - 2.4e-19 68.0 1.3 3.2e-06 26.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ80172.1 - 1.4e-17 62.1 5.2 1.8e-06 27.4 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ80172.1 - 7.6e-11 41.6 6.8 5.6e-05 23.4 0.9 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ80172.1 - 9.6e-10 38.8 2.9 1.5e-05 25.5 1.7 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ80172.1 - 1.1e-08 34.8 8.7 5.4e-06 26.2 0.7 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ80172.1 - 1.7e-07 31.4 3.1 2.1e-05 24.7 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ80172.1 - 1.4e-06 28.3 3.6 0.021 15.2 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ80172.1 - 1.3e-05 24.6 0.1 0.053 13.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ80172.1 - 2.7e-05 23.6 6.3 0.017 14.9 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 KNZ80172.1 - 0.00024 20.2 1.3 0.00048 19.2 0.9 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 KNZ80172.1 - 0.00029 20.9 0.3 0.0038 17.3 0.1 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KNZ80172.1 - 0.076 13.2 1.2 33 5.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ80172.1 - 0.14 12.0 7.3 1 9.2 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Ricin_B_lectin PF00652.17 KNZ80173.1 - 2.9e-33 114.5 21.6 2.2e-20 72.9 4.8 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KNZ80173.1 - 1.1e-15 57.8 5.0 3e-09 37.2 0.5 2.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Aminotran_1_2 PF00155.16 KNZ80174.1 - 2.1e-36 125.6 0.0 3e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KNZ80174.1 - 4.5e-06 25.2 0.0 6.6e-06 24.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KNZ80174.1 - 1.4e-05 24.3 0.1 5.4e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KNZ80174.1 - 0.00017 20.8 0.0 0.00037 19.7 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KNZ80174.1 - 0.00037 19.3 0.0 0.0011 17.8 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V OKR_DC_1 PF01276.15 KNZ80174.1 - 0.0043 15.6 0.0 0.0071 14.9 0.0 1.4 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain SHMT PF00464.14 KNZ80174.1 - 0.009 14.4 0.0 0.016 13.6 0.0 1.3 1 0 0 1 1 1 1 Serine hydroxymethyltransferase FAD_binding_3 PF01494.14 KNZ80175.1 - 2.7e-12 46.4 0.0 2e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KNZ80175.1 - 6.2e-08 31.9 0.1 0.0011 17.9 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KNZ80175.1 - 6.7e-07 29.2 0.0 2.4e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KNZ80175.1 - 1.4e-06 27.6 0.2 0.034 13.2 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KNZ80175.1 - 0.00012 21.0 0.1 0.00028 19.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KNZ80175.1 - 0.00078 19.3 0.0 0.0026 17.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KNZ80175.1 - 0.00091 18.2 0.0 0.66 8.8 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.2 KNZ80175.1 - 0.0016 17.5 0.2 0.0029 16.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KNZ80175.1 - 0.0027 18.0 0.1 0.0096 16.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KNZ80175.1 - 0.0056 15.7 0.1 0.15 11.1 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KNZ80175.1 - 0.0091 14.5 0.0 0.019 13.4 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KNZ80175.1 - 0.12 11.2 0.0 0.23 10.2 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A E1-E2_ATPase PF00122.15 KNZ80176.1 - 1.6e-65 220.3 3.4 3.1e-65 219.4 2.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KNZ80176.1 - 2.3e-30 105.4 6.0 2.3e-30 105.4 4.1 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KNZ80176.1 - 1.9e-22 80.7 0.0 1.7e-21 77.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KNZ80176.1 - 1.6e-15 56.2 0.3 1.6e-15 56.2 0.2 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KNZ80176.1 - 1.8e-15 56.6 0.0 3.4e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KNZ80176.1 - 4.3e-10 40.0 0.0 1e-09 38.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KNZ80176.1 - 0.0046 16.5 0.3 0.023 14.2 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3735 PF12537.3 KNZ80177.1 - 0.067 13.2 1.0 0.16 12.0 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) Arif-1 PF06770.6 KNZ80177.1 - 4.7 6.5 9.0 0.16 11.2 0.5 2.5 2 1 1 3 3 3 0 Actin-rearrangement-inducing factor (Arif-1) Hydrophobin PF01185.13 KNZ80178.1 - 0.00051 20.4 0.1 0.0007 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal hydrophobin TPP_enzyme_N PF02776.13 KNZ80181.1 - 7.4e-39 132.9 0.0 1e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KNZ80181.1 - 4.5e-22 78.2 0.0 9.4e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KNZ80181.1 - 7.5e-11 41.8 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ADH_zinc_N PF00107.21 KNZ80182.1 - 5.2e-32 110.1 1.0 7.3e-32 109.6 0.3 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ80182.1 - 8.3e-29 99.5 2.5 1.7e-28 98.5 1.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MIP-T3 PF10243.4 KNZ80183.1 - 2.1 6.7 80.0 0.075 11.4 16.5 2.8 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 CAF-1_p150 PF11600.3 KNZ80183.1 - 6.5 6.0 91.8 0.12 11.7 31.9 3.2 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FAD_binding_3 PF01494.14 KNZ80184.1 - 1.5e-14 53.8 0.0 6.5e-14 51.7 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KNZ80184.1 - 3.7e-12 45.8 0.9 1.5e-06 27.3 0.2 2.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KNZ80184.1 - 5.3e-08 32.3 0.1 0.00039 19.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 KNZ80184.1 - 2e-07 31.0 0.0 7.6e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ80184.1 - 2.3e-07 30.7 0.4 8.3e-07 28.9 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KNZ80184.1 - 5.3e-06 26.7 0.0 0.00016 22.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KNZ80184.1 - 5.8e-05 22.3 0.0 7.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KNZ80184.1 - 6.3e-05 22.0 0.2 0.0012 17.7 0.2 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KNZ80184.1 - 0.0001 20.9 0.0 0.002 16.6 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KNZ80184.1 - 0.00011 21.2 0.4 0.0002 20.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KNZ80184.1 - 0.00026 19.9 0.1 0.00041 19.3 0.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KNZ80184.1 - 0.014 14.4 0.4 0.033 13.2 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.9 KNZ80184.1 - 0.021 13.4 0.1 0.08 11.5 0.0 2.0 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 KNZ80184.1 - 0.067 13.2 0.1 0.24 11.4 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MBOAT PF03062.14 KNZ80185.1 - 4.8e-45 154.0 28.8 4.8e-45 154.0 20.0 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family LRR_4 PF12799.2 KNZ80186.1 - 0.014 15.0 2.8 0.085 12.5 0.4 2.7 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Hydrophobin PF01185.13 KNZ80187.1 - 2.1e-18 66.5 11.1 2.9e-18 66.1 7.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.7 KNZ80187.1 - 0.18 12.3 11.2 0.17 12.3 2.1 2.3 2 0 0 2 2 2 0 Ion channel inhibitory toxin DUF281 PF03436.8 KNZ80187.1 - 0.36 10.9 7.6 0.3 11.1 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF281) RNase_H PF00075.19 KNZ80188.1 - 0.00068 19.9 0.1 0.0015 18.8 0.1 1.6 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 KNZ80188.1 - 0.002 18.3 0.3 0.0054 17.0 0.1 1.7 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.2 KNZ80188.1 - 0.058 13.2 0.5 0.058 13.2 0.4 1.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Cupin_2 PF07883.6 KNZ80190.1 - 8.6e-30 102.0 1.1 2.7e-14 52.4 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 KNZ80190.1 - 9.5e-28 96.4 0.7 8.1e-14 51.2 0.0 2.4 3 0 0 3 3 3 2 Cupin Cupin_3 PF05899.7 KNZ80190.1 - 1.5e-10 40.2 0.2 4.8e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KNZ80190.1 - 1.3e-07 31.4 0.4 8.7e-06 25.4 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 KNZ80190.1 - 8.8e-05 22.1 0.0 0.0026 17.4 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.9 KNZ80190.1 - 0.0003 20.7 0.6 0.11 12.4 0.0 2.1 2 0 0 2 2 2 2 ARD/ARD' family 3-HAO PF06052.7 KNZ80190.1 - 0.0051 16.2 0.0 0.071 12.5 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase GPI PF06560.6 KNZ80190.1 - 0.091 11.7 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_8 PF13621.1 KNZ80190.1 - 0.098 12.1 0.0 5.8 6.3 0.0 2.6 2 1 0 2 2 2 0 Cupin-like domain DcpS_C PF11969.3 KNZ80191.1 - 3.7e-07 30.3 0.4 4.6e-07 30.0 0.2 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KNZ80191.1 - 0.1 13.1 1.0 0.15 12.6 0.7 1.3 1 0 0 1 1 1 0 HIT domain UCH PF00443.24 KNZ80192.1 - 2.3e-50 171.2 0.0 3.1e-49 167.5 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNZ80192.1 - 2.3e-24 86.3 0.5 2.3e-16 60.1 1.1 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KNZ80192.1 - 4.3e-05 23.5 13.4 4.3e-05 23.5 9.3 3.0 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein RecR PF02132.10 KNZ80192.1 - 3.2 7.2 8.2 5.3 6.5 0.1 3.3 3 0 0 3 3 3 0 RecR protein Thg1C PF14413.1 KNZ80193.1 - 1.4e-46 157.0 0.0 2e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KNZ80193.1 - 9.6e-46 154.7 0.1 1.5e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Pilt PF15453.1 KNZ80194.1 - 0.067 12.8 3.3 0.11 12.2 2.3 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions CK1gamma_C PF12605.3 KNZ80194.1 - 0.24 11.9 2.0 0.55 10.8 1.2 1.9 1 1 0 1 1 1 0 Casein kinase 1 gamma C terminal YL1 PF05764.8 KNZ80194.1 - 0.6 9.6 7.3 0.91 9.0 5.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Fork_head PF00250.13 KNZ80195.1 - 9.7e-21 73.6 1.4 3.8e-20 71.7 0.9 1.9 1 1 0 1 1 1 1 Fork head domain PBP1_TM PF14812.1 KNZ80195.1 - 1.7 9.0 9.4 4.8 7.5 6.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.11 KNZ80197.1 - 5.4e-21 74.7 21.9 5.4e-21 74.7 15.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily COesterase PF00135.23 KNZ80198.1 - 2.1e-90 303.9 0.0 3e-90 303.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ80198.1 - 5.5e-12 45.7 0.1 2.1e-11 43.8 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 KNZ80198.1 - 0.00012 21.6 0.1 0.00037 19.9 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KNZ80198.1 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ80198.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2424 PF10340.4 KNZ80198.1 - 0.14 10.7 0.1 0.45 9.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) RVP_2 PF08284.6 KNZ80200.1 - 0.00059 19.7 0.0 0.0011 18.9 0.0 1.5 1 1 1 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KNZ80200.1 - 0.0006 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ80200.1 - 0.01 16.3 0.0 0.013 15.9 0.0 1.3 1 1 0 1 1 1 0 Aspartyl protease Senescence PF06911.7 KNZ80202.1 - 8.1e-20 71.2 0.8 7.4e-11 42.0 0.0 2.5 2 0 0 2 2 2 2 Senescence-associated protein ATP-synt_C PF00137.16 KNZ80204.1 - 0.62 10.0 9.4 11 6.0 0.4 3.4 3 0 0 3 3 3 0 ATP synthase subunit C Nse4_C PF08743.5 KNZ80206.1 - 3.2e-27 94.3 0.1 7e-27 93.2 0.1 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KNZ80206.1 - 9.2e-19 67.0 0.7 2.1e-18 65.8 0.5 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Hat1_N PF10394.4 KNZ80207.1 - 2.3e-42 144.8 0.1 5.4e-42 143.6 0.1 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 KNZ80207.1 - 0.00024 21.1 0.0 0.00048 20.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ80207.1 - 0.00044 20.2 0.0 0.00087 19.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.13 KNZ80207.1 - 0.002 17.3 0.1 0.0036 16.5 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_3 PF13302.1 KNZ80207.1 - 0.036 14.2 0.2 0.2 11.8 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KNZ80207.1 - 0.041 14.0 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KNZ80207.1 - 0.16 11.9 0.9 0.65 9.9 0.0 2.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DNA_pol_A PF00476.15 KNZ80208.1 - 4.2e-96 321.8 0.0 6.5e-96 321.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 KNZ80208.1 - 0.0016 17.9 0.1 0.021 14.3 0.0 2.4 1 1 0 1 1 1 1 3'-5' exonuclease CoA_trans PF01144.18 KNZ80209.1 - 8.1e-103 342.2 3.1 2.4e-60 203.3 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KNZ80209.1 - 0.00014 21.5 0.1 0.00031 20.4 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 KNZ80209.1 - 0.009 15.7 0.7 0.38 10.4 0.0 2.9 4 0 0 4 4 4 1 Acetyl-CoA hydrolase/transferase N-terminal domain Pkinase PF00069.20 KNZ80211.1 - 4.5e-07 29.2 0.1 7.6e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KNZ80211.1 - 6.4e-07 29.3 0.0 2.3e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KNZ80211.1 - 0.012 14.7 0.1 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.17 KNZ80211.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Chromo PF00385.19 KNZ80212.1 - 8.6e-18 63.7 0.1 1e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Aldo_ket_red PF00248.16 KNZ80213.1 - 2e-34 118.7 0.0 2.7e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GHMP_kinases_N PF00288.21 KNZ80215.1 - 3.6e-08 33.3 5.0 8.3e-08 32.1 3.4 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Exo_endo_phos PF03372.18 KNZ80216.1 - 1e-23 84.5 0.1 1.4e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KNZ80216.1 - 5.6e-16 57.7 3.1 2.5e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNZ80216.1 - 4.4e-13 48.7 4.4 2.1e-08 33.8 0.5 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KNZ80216.1 - 2.3e-07 29.8 2.4 0.037 14.0 0.1 4.9 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KNZ80216.1 - 3.6e-06 26.2 3.1 0.38 11.1 0.4 4.8 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KNZ80216.1 - 0.038 14.0 4.3 1.8 8.8 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat Muskelin_N PF06588.6 KNZ80217.1 - 1.9e-46 158.3 0.0 3.1e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_4 PF13418.1 KNZ80217.1 - 1.6e-25 88.6 2.3 4e-08 32.9 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KNZ80217.1 - 2.5e-23 81.6 13.2 5.4e-10 39.1 0.0 8.2 8 1 0 8 8 8 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KNZ80217.1 - 4.7e-20 71.1 0.3 8.7e-10 38.3 0.0 6.0 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 KNZ80217.1 - 8e-15 54.1 4.6 1e-07 31.3 0.1 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 KNZ80217.1 - 6.4e-13 48.2 3.0 0.00012 22.0 0.0 6.8 8 0 0 8 8 8 2 Kelch motif F5_F8_type_C PF00754.20 KNZ80217.1 - 4.2e-05 23.3 0.7 0.00015 21.6 0.0 2.3 3 0 0 3 3 3 1 F5/8 type C domain Sad1_UNC PF07738.8 KNZ80217.1 - 0.037 13.8 0.0 0.086 12.6 0.0 1.6 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Prefoldin_2 PF01920.15 KNZ80219.1 - 1.7e-23 82.3 6.0 2.3e-23 81.9 4.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 KNZ80219.1 - 0.0012 18.4 6.2 0.16 11.6 1.1 2.2 1 1 1 2 2 2 2 Prefoldin subunit FliD_C PF07195.7 KNZ80219.1 - 0.0037 16.5 1.1 0.084 12.1 0.0 2.0 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus Seryl_tRNA_N PF02403.17 KNZ80219.1 - 0.0079 16.1 7.2 0.62 10.0 0.1 2.2 2 0 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 KNZ80219.1 - 0.0096 15.3 9.2 0.13 11.8 2.9 2.2 2 0 0 2 2 2 1 Septum formation initiator DUF4140 PF13600.1 KNZ80219.1 - 0.012 15.9 3.6 0.62 10.5 1.2 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HrpB7 PF09486.5 KNZ80219.1 - 0.016 15.1 1.7 2.3 8.1 0.5 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) FTA4 PF13093.1 KNZ80219.1 - 0.016 14.6 3.0 0.018 14.4 2.1 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Spc24 PF08286.6 KNZ80219.1 - 0.018 14.7 7.7 1.4 8.6 3.1 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 AAA_23 PF13476.1 KNZ80219.1 - 0.032 14.5 3.2 0.038 14.3 2.2 1.2 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 KNZ80219.1 - 0.033 14.0 9.7 1.4 8.7 0.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AAA_18 PF13238.1 KNZ80219.1 - 0.035 14.3 0.1 0.043 14.1 0.1 1.1 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 KNZ80219.1 - 0.048 14.0 2.8 1.8 8.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF465 PF04325.8 KNZ80219.1 - 0.056 13.1 0.3 0.056 13.1 0.2 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF465) FlaC_arch PF05377.6 KNZ80219.1 - 0.062 13.2 2.7 0.92 9.4 0.4 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Vps51 PF08700.6 KNZ80219.1 - 0.065 13.0 1.4 1.8 8.4 0.2 2.4 2 0 0 2 2 2 0 Vps51/Vps67 Snf7 PF03357.16 KNZ80219.1 - 0.082 12.2 5.4 0.34 10.2 0.1 2.2 2 0 0 2 2 2 0 Snf7 Katanin_con80 PF13925.1 KNZ80219.1 - 0.11 12.2 1.1 0.13 11.9 0.1 1.5 2 0 0 2 2 2 0 con80 domain of Katanin Laminin_II PF06009.7 KNZ80219.1 - 0.13 12.0 1.9 0.97 9.1 0.5 2.2 2 0 0 2 2 2 0 Laminin Domain II Spc7 PF08317.6 KNZ80219.1 - 0.14 10.7 8.4 0.19 10.3 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.3 KNZ80219.1 - 0.19 11.5 7.0 4.1 7.3 0.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KNZ80219.1 - 0.21 11.1 11.8 0.57 9.7 8.2 1.5 1 1 0 1 1 1 0 IncA protein TBPIP PF07106.8 KNZ80219.1 - 0.22 11.0 7.9 2.5 7.6 1.9 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DASH_Dam1 PF08653.5 KNZ80219.1 - 0.22 11.3 2.8 1.2 8.9 0.5 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 FliD_N PF02465.13 KNZ80219.1 - 0.41 11.0 2.8 6.1 7.2 0.2 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4200 PF13863.1 KNZ80219.1 - 0.47 10.4 7.7 2.5 8.0 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF607 PF04678.8 KNZ80219.1 - 0.7 9.7 4.3 0.57 10.0 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF607 GAS PF13851.1 KNZ80219.1 - 0.9 8.7 10.0 3.9 6.6 7.0 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ax_dynein_light PF10211.4 KNZ80219.1 - 0.96 9.2 6.6 5.1 6.8 2.0 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain FlxA PF14282.1 KNZ80219.1 - 1 9.3 7.8 0.79 9.7 0.8 2.3 2 0 0 2 2 2 0 FlxA-like protein DASH_Dad3 PF08656.5 KNZ80219.1 - 1 9.0 6.4 0.44 10.2 0.8 2.5 3 0 0 3 3 2 0 DASH complex subunit Dad3 Prp18 PF02840.10 KNZ80219.1 - 1.3 8.8 3.6 0.82 9.4 0.9 1.7 1 1 1 2 2 2 0 Prp18 domain Fib_alpha PF08702.5 KNZ80219.1 - 1.5 8.9 5.4 11 6.0 3.5 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family M PF02370.11 KNZ80219.1 - 1.8 9.1 10.3 4.9 7.8 4.0 2.9 2 0 0 2 2 2 0 M protein repeat DivIVA PF05103.8 KNZ80219.1 - 2.1 8.4 7.3 14 5.7 5.0 2.0 1 1 0 1 1 1 0 DivIVA protein DUF342 PF03961.8 KNZ80219.1 - 2.1 6.6 4.7 1.6 7.0 1.5 1.5 1 1 0 2 2 2 0 Protein of unknown function (DUF342) NTR2 PF15458.1 KNZ80219.1 - 2.5 7.2 11.5 6.2 5.9 0.2 2.2 1 1 0 2 2 2 0 Nineteen complex-related protein 2 Rho_Binding PF08912.6 KNZ80219.1 - 2.6 8.4 8.7 1.9 8.8 2.6 2.5 2 1 0 2 2 2 0 Rho Binding bZIP_1 PF00170.16 KNZ80219.1 - 4.3 7.3 8.2 2.1 8.3 1.9 2.4 2 0 0 2 2 2 0 bZIP transcription factor V_ATPase_I PF01496.14 KNZ80219.1 - 4.6 4.9 6.5 7.1 4.3 4.5 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0449 PF15136.1 KNZ80219.1 - 5.3 7.3 6.4 9.4 6.5 1.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 EMP24_GP25L PF01105.19 KNZ80219.1 - 5.6 6.6 6.9 2.4 7.8 1.8 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Pyridoxal_deC PF00282.14 KNZ80220.1 - 1.7e-11 43.2 0.0 3.3e-11 42.2 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KNZ80220.1 - 3.9e-05 22.5 0.0 0.00039 19.2 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KNZ80220.1 - 0.0037 16.3 0.1 0.0058 15.7 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Arrestin_N PF00339.24 KNZ80221.1 - 4.2e-09 36.3 0.0 3.1e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KNZ80221.1 - 5.6e-09 36.2 0.3 8.4e-07 29.1 0.1 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 KNZ80221.1 - 0.00072 19.0 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Ank_5 PF13857.1 KNZ80222.1 - 5e-05 23.4 0.0 0.00022 21.3 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KNZ80222.1 - 7.6e-05 22.9 0.0 0.00018 21.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Acetyltransf_7 PF13508.1 KNZ80222.1 - 0.00022 21.3 0.0 0.00057 20.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank PF00023.25 KNZ80222.1 - 0.00042 19.9 0.1 0.0023 17.6 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 KNZ80222.1 - 0.0019 18.2 0.0 0.0075 16.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 KNZ80222.1 - 0.0036 17.7 0.0 0.012 16.0 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) peroxidase PF00141.18 KNZ80223.1 - 5.7e-48 163.3 0.0 9.3e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF4366 PF14283.1 KNZ80223.1 - 0.023 14.1 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) zf-LYAR PF08790.6 KNZ80225.1 - 2.2e-13 49.6 3.5 4e-13 48.8 2.4 1.4 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Autophagy_N PF03986.8 KNZ80226.1 - 1.2e-46 158.0 0.5 2e-46 157.3 0.0 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KNZ80226.1 - 4.7e-24 84.3 0.5 9.1e-24 83.4 0.4 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KNZ80226.1 - 6.6e-12 44.3 3.2 6.6e-12 44.3 2.2 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein C-terminal DUF1253 PF06862.7 KNZ80227.1 - 2e-131 438.4 0.0 2.7e-131 438.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Topoisom_bac PF01131.15 KNZ80228.1 - 2.9e-94 316.1 0.0 3.4e-94 315.9 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 KNZ80228.1 - 5e-20 71.3 0.0 2.3e-19 69.2 0.0 2.2 3 0 0 3 3 3 1 Toprim domain CPSF_A PF03178.10 KNZ80230.1 - 3e-91 305.8 0.0 2.2e-90 303.0 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 KNZ80230.1 - 1.4e-78 264.2 0.0 2.1e-78 263.6 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term OsmC PF02566.14 KNZ80231.1 - 3.2e-13 49.7 0.0 4.6e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein CHD5 PF04420.9 KNZ80232.1 - 4.5e-43 146.6 0.6 5.2e-43 146.4 0.4 1.1 1 0 0 1 1 1 1 CHD5-like protein Lipoprotein_6 PF01441.14 KNZ80232.1 - 0.00059 19.7 0.9 0.0008 19.3 0.6 1.2 1 0 0 1 1 1 1 Lipoprotein Malate_synthase PF01274.17 KNZ80233.1 - 1.5e-197 656.7 0.0 1.7e-197 656.5 0.0 1.0 1 0 0 1 1 1 1 Malate synthase FKBP_C PF00254.23 KNZ80234.1 - 5e-33 112.9 0.0 6.3e-33 112.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SynMuv_product PF06047.6 KNZ80235.1 - 1.8e-42 143.2 6.3 1.8e-42 143.2 4.4 2.7 3 0 0 3 3 3 1 Ras-induced vulval development antagonist Gln-synt_C PF00120.19 KNZ80236.1 - 4.1e-55 186.7 0.0 5.2e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF3216 PF11505.3 KNZ80238.1 - 0.036 13.8 0.1 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Gln-synt_C PF00120.19 KNZ80241.1 - 1.2e-56 191.7 0.0 1.5e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Fungal_trans PF04082.13 KNZ80242.1 - 5.8e-30 104.0 0.2 5.8e-30 104.0 0.1 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 KNZ80242.1 - 0.11 12.4 0.5 0.28 11.1 0.4 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain Asp_protease_2 PF13650.1 KNZ80243.1 - 7.1e-06 26.4 0.0 1.1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ80243.1 - 0.00044 19.8 0.2 0.0015 18.0 0.1 1.8 1 1 1 2 2 2 1 Aspartyl protease Amnionless PF14828.1 KNZ80246.1 - 0.22 9.9 0.0 0.34 9.3 0.0 1.2 1 0 0 1 1 1 0 Amnionless WSC PF01822.14 KNZ80247.1 - 7.6e-36 121.9 21.3 2.8e-18 65.6 6.0 2.3 2 0 0 2 2 2 2 WSC domain Vps53_N PF04100.7 KNZ80248.1 - 1.8e-86 290.3 1.3 1.8e-86 290.3 0.9 1.5 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2450 PF10475.4 KNZ80248.1 - 1e-07 31.1 1.0 2e-07 30.2 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) IncA PF04156.9 KNZ80248.1 - 0.0021 17.6 2.9 0.0076 15.8 2.0 1.9 1 0 0 1 1 1 1 IncA protein FlxA PF14282.1 KNZ80248.1 - 0.25 11.2 9.5 0.28 11.1 4.8 2.3 2 0 0 2 2 2 0 FlxA-like protein DUF1664 PF07889.7 KNZ80248.1 - 4.6 7.0 12.4 0.48 10.2 3.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 KNZ80248.1 - 6.4 6.2 12.5 0.79 9.2 4.6 2.3 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Yippee-Mis18 PF03226.9 KNZ80249.1 - 6.1e-13 48.6 0.1 1.5e-12 47.3 0.1 1.6 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Rpr2 PF04032.11 KNZ80250.1 - 9.4e-22 76.6 3.4 7.6e-21 73.7 2.3 2.0 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF164 PF02591.10 KNZ80250.1 - 0.071 12.9 1.9 0.9 9.4 1.4 2.4 1 1 0 1 1 1 0 Putative zinc ribbon domain Hormone_6 PF00236.13 KNZ80250.1 - 0.097 12.4 1.1 0.18 11.6 0.1 1.9 1 1 0 2 2 2 0 Glycoprotein hormone MRP-L27 PF09809.4 KNZ80251.1 - 7.6e-08 31.9 0.1 1.3e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 HCO3_cotransp PF00955.16 KNZ80252.1 - 1.6e-42 145.8 16.4 1.5e-19 70.1 1.9 3.1 2 1 1 3 3 3 3 HCO3- transporter family Ctr PF04145.10 KNZ80253.1 - 5.8e-39 133.4 0.1 6.8e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF4131 PF13567.1 KNZ80253.1 - 0.22 10.8 2.1 8.8 5.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Proteasome PF00227.21 KNZ80254.1 - 2.2e-53 180.4 0.1 1.2e-52 177.9 0.0 2.3 2 0 0 2 2 2 1 Proteasome subunit Ank_5 PF13857.1 KNZ80254.1 - 2.2e-05 24.5 0.0 0.00013 22.0 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KNZ80254.1 - 4.8e-05 23.6 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNZ80254.1 - 0.00066 20.1 0.0 0.01 16.3 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KNZ80254.1 - 0.001 18.7 0.0 0.0066 16.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Acetyltransf_7 PF13508.1 KNZ80254.1 - 0.0014 18.7 0.0 0.0054 16.8 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank_3 PF13606.1 KNZ80254.1 - 0.0032 17.5 0.0 0.023 14.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Acetyltransf_1 PF00583.19 KNZ80254.1 - 0.036 14.1 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Bac_rhamnosid_N PF08531.5 KNZ80255.1 - 3.1e-08 33.3 2.6 0.0028 17.2 0.0 5.1 2 2 0 4 4 4 3 Alpha-L-rhamnosidase N-terminal domain OSCP PF00213.13 KNZ80256.1 - 0.1 12.4 0.1 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit CHZ PF09649.5 KNZ80258.1 - 2.6e-08 32.9 0.6 2.6e-08 32.9 0.4 2.3 2 0 0 2 2 2 1 Histone chaperone domain CHZ FAM176 PF14851.1 KNZ80258.1 - 0.075 12.7 9.8 0.082 12.5 6.1 1.6 1 1 0 1 1 1 0 FAM176 family Ank_2 PF12796.2 KNZ80259.1 - 0.00047 20.4 0.1 0.007 16.6 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNZ80259.1 - 0.0012 19.2 0.3 0.006 17.0 0.1 2.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Acetyltransf_7 PF13508.1 KNZ80259.1 - 0.0015 18.6 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank_5 PF13857.1 KNZ80259.1 - 0.0027 17.8 0.1 0.015 15.5 0.1 2.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KNZ80259.1 - 0.0056 16.4 0.0 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Acetyltransf_1 PF00583.19 KNZ80259.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family SKI PF01202.17 KNZ80260.1 - 0.043 13.6 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate kinase UBN2_2 PF14227.1 KNZ80260.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type bZIP_2 PF07716.10 KNZ80262.1 - 1e-09 38.0 14.4 1.7e-09 37.3 10.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KNZ80262.1 - 2.3e-08 33.8 12.4 3.6e-08 33.2 8.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KNZ80262.1 - 0.023 14.9 6.6 0.023 14.9 4.6 1.6 2 0 0 2 2 2 0 bZIP Maf transcription factor WD40_alt PF14077.1 KNZ80262.1 - 0.15 11.7 0.3 0.33 10.6 0.2 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif Dmrt1 PF12374.3 KNZ80262.1 - 5 7.5 8.2 9.1 6.7 0.4 3.1 3 0 0 3 3 3 0 Double-sex mab3 related transcription factor 1 F-box-like PF12937.2 KNZ80263.1 - 0.00026 20.6 0.2 0.00084 19.0 0.2 2.0 1 0 0 1 1 1 1 F-box-like RNase_H PF00075.19 KNZ80265.1 - 3.6e-06 27.3 0.0 8.9e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.1 KNZ80265.1 - 2.1e-05 24.7 0.3 4.7e-05 23.6 0.2 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Collagen PF01391.13 KNZ80266.1 - 0.0012 18.3 22.1 0.0012 18.3 15.4 2.3 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Glyco_hydro_63 PF03200.11 KNZ80267.1 - 7.1e-07 27.4 10.1 1.7e-06 26.2 1.3 3.7 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase RhoGAP PF00620.22 KNZ80268.1 - 1.5e-29 102.6 0.0 2.7e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Mito_carr PF00153.22 KNZ80269.1 - 4e-76 250.8 1.3 1.1e-27 95.5 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein CMD PF02627.15 KNZ80270.1 - 5.6e-14 51.7 0.0 3.7e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family NAD_binding_11 PF14833.1 KNZ80271.1 - 2.6e-27 95.2 0.1 4.8e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 KNZ80271.1 - 1.1e-26 93.6 0.0 1.5e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Spc97_Spc98 PF04130.8 KNZ80272.1 - 2.6e-39 134.9 0.0 3.3e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF2367 PF10164.4 KNZ80273.1 - 3.7e-08 33.1 1.9 4.9e-08 32.7 1.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) Methyltransf_31 PF13847.1 KNZ80274.1 - 3.2e-10 39.7 0.7 1.1e-09 38.0 0.5 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ80274.1 - 9e-09 35.9 0.0 2.2e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KNZ80274.1 - 2.3e-07 30.2 1.3 2.1e-06 27.0 0.9 2.1 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 KNZ80274.1 - 7e-07 28.5 0.0 9.9e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 KNZ80274.1 - 3.4e-06 27.4 0.6 0.0001 22.7 0.1 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ80274.1 - 1.7e-05 24.5 0.0 4.2e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ80274.1 - 2.3e-05 24.3 0.0 8.7e-05 22.5 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KNZ80274.1 - 8.5e-05 21.9 0.6 0.00047 19.5 0.4 2.0 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KNZ80274.1 - 0.0003 19.9 0.0 0.00053 19.1 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 KNZ80274.1 - 0.00031 19.5 0.1 0.00074 18.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 KNZ80274.1 - 0.0016 18.7 0.0 0.0036 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ80274.1 - 0.0028 18.0 0.1 0.0073 16.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KNZ80274.1 - 0.01 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KNZ80274.1 - 0.028 13.5 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 KNZ80274.1 - 0.035 13.6 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 KNZ80274.1 - 0.052 12.7 0.4 0.21 10.7 0.3 2.2 1 1 0 1 1 1 0 Tellurite resistance protein TehB UPF0020 PF01170.13 KNZ80274.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Glyco_hydro_28 PF00295.12 KNZ80275.1 - 5.7e-56 189.8 12.2 7e-56 189.5 8.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KNZ80275.1 - 2.9e-07 30.3 28.0 4.6e-07 29.7 15.1 2.6 1 1 1 2 2 2 1 Right handed beta helix region NosD PF05048.8 KNZ80275.1 - 2.5e-05 23.5 6.9 4.8e-05 22.6 4.8 1.5 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.6 KNZ80275.1 - 0.004 16.3 7.7 0.004 16.3 5.4 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1565) RhoGEF PF00621.15 KNZ80276.1 - 4.9e-39 134.0 3.9 7.8e-39 133.4 2.7 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 KNZ80276.1 - 4.2e-28 97.8 0.0 8.9e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 KNZ80276.1 - 2.3e-17 62.4 0.0 4.5e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.6 KNZ80276.1 - 2.4e-11 43.5 0.0 4.6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin Rap1-DNA-bind PF09197.5 KNZ80277.1 - 0.00042 20.8 6.4 0.45 11.0 1.4 3.5 2 1 1 3 3 3 3 Rap1, DNA-binding Myb_DNA-bind_2 PF08914.6 KNZ80277.1 - 0.00078 19.1 7.6 0.11 12.3 0.2 3.9 4 0 0 4 4 4 2 Rap1 Myb domain PhyH PF05721.8 KNZ80278.1 - 6.1e-47 160.3 0.0 7.4e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) LRR_4 PF12799.2 KNZ80279.1 - 0.011 15.3 0.2 4.3 7.0 0.0 4.0 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNZ80279.1 - 0.3 10.8 6.0 2.7 7.8 0.2 4.2 3 1 0 3 3 3 0 Leucine rich repeat UvrD_C_2 PF13538.1 KNZ80281.1 - 0.0029 17.7 0.0 0.0029 17.7 0.0 1.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF3086 PF11285.3 KNZ80281.1 - 0.062 12.1 0.0 0.07 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Herpes_Helicase PF02689.9 KNZ80281.1 - 0.086 10.5 0.0 0.086 10.5 0.0 1.0 1 0 0 1 1 1 0 Helicase Sugar_tr PF00083.19 KNZ80282.1 - 1.8e-89 300.4 20.0 3.6e-89 299.4 13.8 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ80282.1 - 5e-24 84.6 27.3 2.2e-21 75.9 8.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KNZ80282.1 - 0.032 14.0 4.1 0.74 9.6 0.0 3.7 3 1 0 3 3 3 0 MFS_1 like family BUD22 PF09073.5 KNZ80283.1 - 0.0051 15.9 1.6 0.0051 15.9 1.1 3.3 3 1 0 3 3 3 1 BUD22 DZR PF12773.2 KNZ80284.1 - 0.86 9.4 9.6 0.096 12.5 3.3 1.9 2 0 0 2 2 2 0 Double zinc ribbon Pro_isomerase PF00160.16 KNZ80285.1 - 1.3e-45 155.3 0.6 1.5e-45 155.1 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD gag_pre-integrs PF13976.1 KNZ80287.1 - 4.3e-09 35.8 0.0 1.1e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 KNZ80287.1 - 2.8e-05 24.2 0.0 5.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF3808 PF10300.4 KNZ80288.1 - 3.3e-56 190.7 0.0 1.3e-44 152.5 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_16 PF13432.1 KNZ80288.1 - 0.0045 17.6 0.6 5.4 7.8 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ80288.1 - 0.0083 15.7 0.9 6.9 6.3 0.1 3.4 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KNZ80288.1 - 0.041 13.8 5.5 0.59 10.1 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Cu-oxidase PF00394.17 KNZ80289.1 - 1.8e-42 144.9 0.0 9.6e-41 139.3 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KNZ80289.1 - 3.3e-36 123.5 0.2 2.6e-34 117.4 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KNZ80289.1 - 7.5e-35 119.4 4.5 2e-31 108.3 0.0 2.9 2 1 0 2 2 2 2 Multicopper oxidase Dynamin_M PF01031.15 KNZ80290.1 - 1.1e-30 106.5 0.0 1.7e-29 102.5 0.0 2.1 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KNZ80290.1 - 3.1e-25 88.9 0.0 9.9e-25 87.2 0.0 1.9 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 KNZ80290.1 - 2.5e-11 43.3 0.6 1.3e-10 41.0 0.0 2.5 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KNZ80290.1 - 6.1e-05 22.9 0.1 0.00067 19.5 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KNZ80290.1 - 0.043 14.3 1.0 0.095 13.2 0.1 2.2 2 1 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 KNZ80290.1 - 0.049 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNase_H PF00075.19 KNZ80291.1 - 0.006 16.9 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KNZ80291.1 - 0.008 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like T2SM PF04612.7 KNZ80291.1 - 0.15 11.8 2.1 7.8 6.2 0.5 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF1479 PF07350.7 KNZ80292.1 - 2.9e-48 164.3 0.5 7.5e-45 153.1 0.1 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF1479) Peptidase_M48 PF01435.13 KNZ80293.1 - 1.7e-31 109.5 0.1 2.9e-31 108.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M10 PF00413.19 KNZ80293.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF2268 PF10026.4 KNZ80293.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) UBN2_2 PF14227.1 KNZ80298.1 - 7.1e-06 25.5 0.5 1.1e-05 24.9 0.4 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ80298.1 - 0.00061 19.5 1.2 0.00085 19.1 0.1 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KNZ80298.1 - 0.0055 16.2 3.0 0.0094 15.5 2.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type IncA PF04156.9 KNZ80298.1 - 0.03 13.9 0.7 0.043 13.4 0.5 1.3 1 0 0 1 1 1 0 IncA protein LamB_YcsF PF03746.11 KNZ80299.1 - 2.5e-64 216.6 0.0 2.8e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family AAA PF00004.24 KNZ80300.1 - 7.4e-44 149.1 0.0 1.4e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KNZ80300.1 - 2.7e-08 33.9 0.0 5.9e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KNZ80300.1 - 1e-06 28.5 0.0 5.5e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KNZ80300.1 - 4.6e-06 26.7 0.0 2.6e-05 24.2 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KNZ80300.1 - 6e-06 26.4 0.0 0.00032 20.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ80300.1 - 7.3e-05 23.5 0.0 0.00018 22.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KNZ80300.1 - 8.3e-05 21.7 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KNZ80300.1 - 0.00011 21.8 0.1 0.00034 20.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KNZ80300.1 - 0.00038 19.9 0.0 0.00088 18.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KNZ80300.1 - 0.00052 19.9 0.0 0.0026 17.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KNZ80300.1 - 0.00094 18.0 0.0 0.0019 17.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KNZ80300.1 - 0.0015 18.4 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KNZ80300.1 - 0.0022 17.1 0.0 0.005 15.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 KNZ80300.1 - 0.003 17.5 0.0 0.0075 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KNZ80300.1 - 0.0038 16.8 0.0 0.0082 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KNZ80300.1 - 0.0055 17.0 0.0 0.029 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 KNZ80300.1 - 0.0066 15.7 0.0 0.078 12.1 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 KNZ80300.1 - 0.0074 15.4 0.1 0.018 14.2 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KNZ80300.1 - 0.013 14.5 0.0 0.031 13.4 0.0 1.6 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 KNZ80300.1 - 0.018 14.5 0.0 0.098 12.1 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_25 PF13481.1 KNZ80300.1 - 0.019 14.3 0.1 0.081 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KNZ80300.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KNZ80300.1 - 0.028 13.3 0.0 0.056 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KNZ80300.1 - 0.036 14.2 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KNZ80300.1 - 0.047 13.3 0.0 0.59 9.7 0.0 2.2 1 1 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 KNZ80300.1 - 0.052 13.6 0.0 0.18 11.8 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KNZ80300.1 - 0.052 12.4 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DivIC PF04977.10 KNZ80300.1 - 0.054 12.9 0.1 0.21 11.0 0.1 2.0 1 0 0 1 1 1 0 Septum formation initiator AAA_11 PF13086.1 KNZ80300.1 - 0.094 12.2 0.0 0.25 10.8 0.0 1.8 2 1 0 2 2 1 0 AAA domain NB-ARC PF00931.17 KNZ80300.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PIN_4 PF13638.1 KNZ80301.1 - 1.4e-07 31.7 0.0 3.3e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 PIN domain DUF1778 PF08681.6 KNZ80302.1 - 0.38 10.5 6.4 0.22 11.4 2.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) Redoxin PF08534.5 KNZ80305.1 - 2.5e-28 98.4 0.1 2.8e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KNZ80305.1 - 2.7e-11 43.2 0.0 3.1e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family TPP_enzyme_N PF02776.13 KNZ80306.1 - 5.2e-33 113.9 0.1 9.2e-33 113.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KNZ80306.1 - 2.7e-13 49.7 0.0 5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KNZ80306.1 - 1.8e-11 43.9 0.0 1.4e-10 41.0 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.1 KNZ80306.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DLH PF01738.13 KNZ80307.1 - 9.7e-10 38.0 0.0 2.6e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KNZ80307.1 - 0.00076 19.2 0.0 0.0017 18.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family AAA PF00004.24 KNZ80308.1 - 6.5e-86 285.2 0.0 1.9e-42 144.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KNZ80308.1 - 2.8e-11 43.3 0.0 1.5e-05 24.7 0.0 4.6 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KNZ80308.1 - 6.2e-11 41.7 0.0 0.00043 19.4 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KNZ80308.1 - 6.5e-11 42.5 0.6 5e-06 26.6 0.0 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.9 KNZ80308.1 - 6.8e-11 42.3 0.0 0.00041 20.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KNZ80308.1 - 8.2e-10 38.9 0.1 0.00016 21.8 0.0 4.4 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KNZ80308.1 - 2.6e-08 33.5 0.0 0.00021 20.7 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 KNZ80308.1 - 4.1e-08 33.1 0.0 0.00048 20.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KNZ80308.1 - 2e-07 30.6 0.6 0.00035 20.2 0.1 3.8 3 0 0 3 3 3 1 Part of AAA domain AAA_25 PF13481.1 KNZ80308.1 - 3.4e-07 29.8 2.2 0.4 10.0 0.0 4.3 2 2 1 4 4 4 1 AAA domain AAA_33 PF13671.1 KNZ80308.1 - 4.5e-07 29.8 0.0 0.00015 21.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KNZ80308.1 - 5.2e-07 28.7 0.0 0.0047 15.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 KNZ80308.1 - 6.7e-07 28.6 0.0 0.00031 19.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 KNZ80308.1 - 1.2e-05 26.0 0.0 0.00046 20.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KNZ80308.1 - 6.6e-05 22.6 0.1 0.043 13.4 0.0 3.6 4 0 0 4 4 3 1 NACHT domain Mg_chelatase PF01078.16 KNZ80308.1 - 9.2e-05 21.6 0.1 0.16 11.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KNZ80308.1 - 0.00031 20.8 0.0 0.04 14.0 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Sigma54_activ_2 PF14532.1 KNZ80308.1 - 0.00039 20.4 0.0 0.32 11.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_11 PF13086.1 KNZ80308.1 - 0.0016 18.0 0.0 0.013 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KNZ80308.1 - 0.0016 18.3 0.0 0.097 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KNZ80308.1 - 0.0025 18.1 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.4 KNZ80308.1 - 0.0031 16.5 0.0 0.0076 15.2 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 Bac_DnaA PF00308.13 KNZ80308.1 - 0.0033 17.0 0.0 0.27 10.8 0.0 3.2 2 2 0 2 2 2 1 Bacterial dnaA protein Arch_ATPase PF01637.13 KNZ80308.1 - 0.0051 16.5 0.0 1.3 8.6 0.0 3.6 2 2 1 3 3 3 1 Archaeal ATPase Viral_helicase1 PF01443.13 KNZ80308.1 - 0.0083 15.6 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 KNZ80308.1 - 0.012 15.2 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KNZ80308.1 - 0.015 14.5 0.0 0.52 9.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 KNZ80308.1 - 0.015 14.7 0.0 0.78 9.2 0.0 3.2 2 1 0 2 2 2 0 Sigma-54 interaction domain UPF0079 PF02367.12 KNZ80308.1 - 0.039 13.5 0.0 0.67 9.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 KNZ80308.1 - 0.043 12.6 0.0 0.2 10.4 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 KNZ80308.1 - 0.05 12.7 0.0 7 5.7 0.0 2.7 2 0 0 2 2 2 0 KaiC ATP-synt_ab PF00006.20 KNZ80308.1 - 0.051 13.0 0.0 0.21 11.0 0.0 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 KNZ80308.1 - 0.063 12.8 0.4 4.5 6.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.10 KNZ80308.1 - 0.064 11.9 0.3 1.1 7.8 0.1 2.6 2 2 1 3 3 3 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 KNZ80308.1 - 0.081 12.6 0.7 1.3 8.7 0.0 3.2 3 2 2 5 5 4 0 NTPase ABC_tran PF00005.22 KNZ80308.1 - 0.083 13.1 0.0 0.61 10.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AFG1_ATPase PF03969.11 KNZ80308.1 - 0.11 11.2 0.0 1 8.0 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase AAA_30 PF13604.1 KNZ80308.1 - 0.16 11.5 0.0 0.38 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Gpi16 PF04113.9 KNZ80309.1 - 2.5e-137 458.2 0.1 1.6e-70 237.7 0.0 2.0 1 1 1 2 2 2 2 Gpi16 subunit, GPI transamidase component Ca_hom_mod PF14798.1 KNZ80310.1 - 0.056 12.3 0.2 0.062 12.2 0.1 1.1 1 0 0 1 1 1 0 Calcium homeostasis modulator Albumin_I PF08027.6 KNZ80310.1 - 1.5 8.5 4.5 1.8 8.3 3.1 1.3 1 1 0 1 1 1 0 Albumin I F1F0-ATPsyn_F PF10791.4 KNZ80311.1 - 2.3e-22 79.0 0.0 3.1e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi AAA_29 PF13555.1 KNZ80311.1 - 0.2 11.1 0.4 3.2 7.3 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Abi PF02517.11 KNZ80312.1 - 7.2e-14 51.6 3.8 7.2e-14 51.6 2.6 2.8 2 1 0 2 2 2 1 CAAX protease self-immunity Mhr1 PF12829.2 KNZ80313.1 - 0.027 14.3 0.2 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination Viral_DNA_bp PF00747.12 KNZ80313.1 - 0.048 10.8 0.0 0.056 10.6 0.0 1.0 1 0 0 1 1 1 0 ssDNA binding protein DUF217 PF02697.9 KNZ80313.1 - 0.1 12.8 0.2 2.4 8.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 Glyco_hydro_2 PF00703.16 KNZ80314.1 - 5.3e-07 30.0 0.2 2.3e-06 28.0 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KNZ80314.1 - 0.00043 19.8 0.1 0.00099 18.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain F-box PF00646.28 KNZ80315.1 - 0.00037 20.0 7.3 0.023 14.3 0.3 2.6 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.2 KNZ80315.1 - 0.025 14.2 0.2 0.025 14.2 0.1 2.6 3 0 0 3 3 3 0 F-box-like ELK PF03789.8 KNZ80315.1 - 0.4 10.5 2.8 0.89 9.4 2.0 1.6 1 0 0 1 1 1 0 ELK domain Peptidase_C97 PF05903.9 KNZ80316.1 - 7.9e-38 129.5 0.0 1.3e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 KNZ80316.1 - 1.7e-26 92.6 0.1 2.7e-26 91.9 0.1 1.3 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 KNZ80316.1 - 4.9e-16 58.3 0.0 1e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KNZ80316.1 - 1.7e-05 25.0 0.0 0.00041 20.5 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain ArfGap PF01412.13 KNZ80317.1 - 4.3e-33 113.5 0.7 4.3e-33 113.5 0.5 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf adh_short_C2 PF13561.1 KNZ80318.1 - 6.8e-22 78.4 0.0 7.3e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KNZ80318.1 - 7e-12 45.5 0.0 9.1e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ80318.1 - 0.0003 20.4 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 KR domain CholecysA-Rec_N PF09193.5 KNZ80318.1 - 0.0062 16.3 0.5 0.014 15.2 0.1 1.8 2 0 0 2 2 2 1 Cholecystokinin A receptor, N-terminal Asp PF00026.18 KNZ80319.1 - 1.4e-10 40.9 0.0 2.1e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KNZ80319.1 - 0.048 14.1 0.0 3.3 8.2 0.0 2.7 2 0 0 2 2 2 0 Aspartyl protease LRR_4 PF12799.2 KNZ80320.1 - 0.032 13.8 13.2 0.65 9.6 0.0 6.2 4 3 3 7 7 7 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KNZ80320.1 - 0.5 10.5 9.9 7.6 6.9 0.1 5.2 7 0 0 7 7 7 0 Leucine Rich repeat LRR_7 PF13504.1 KNZ80320.1 - 8.2 7.1 11.0 25 5.6 0.0 6.5 8 2 0 8 8 8 0 Leucine rich repeat UBN2_2 PF14227.1 KNZ80321.1 - 9.6e-09 34.8 0.0 1.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ80321.1 - 2.2e-07 30.6 0.0 2.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type ATP_bind_3 PF01171.15 KNZ80322.1 - 0.19 11.1 0.1 0.42 10.0 0.0 1.5 1 0 0 1 1 1 0 PP-loop family Chromo PF00385.19 KNZ80323.1 - 1.6e-08 34.0 0.1 3.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain F-box-like PF12937.2 KNZ80323.1 - 0.00043 19.9 0.2 0.0013 18.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like ATP_bind_3 PF01171.15 KNZ80323.1 - 0.19 11.2 0.1 0.39 10.1 0.0 1.4 1 0 0 1 1 1 0 PP-loop family LRR_4 PF12799.2 KNZ80323.1 - 0.3 10.7 7.5 1.8 8.2 0.0 4.4 3 3 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KNZ80323.1 - 5.9 7.2 6.2 6.3 7.1 0.2 3.6 4 0 0 4 4 4 0 Leucine Rich repeat Chromo PF00385.19 KNZ80324.1 - 1.3e-17 63.1 0.3 1.7e-17 62.8 0.2 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KNZ80324.1 - 0.021 14.7 0.2 0.03 14.2 0.2 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Tudor-knot PF11717.3 KNZ80324.1 - 0.12 12.1 0.4 0.16 11.6 0.3 1.3 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain KBP_C PF12309.3 KNZ80325.1 - 0.039 12.9 1.5 0.061 12.2 1.1 1.2 1 0 0 1 1 1 0 KIF-1 binding protein C terminal Isochorismatase PF00857.15 KNZ80325.1 - 0.065 13.1 0.6 0.19 11.6 0.0 2.1 2 1 1 3 3 3 0 Isochorismatase family PIF1 PF05970.9 KNZ80326.1 - 3.3e-33 115.1 0.0 3.6e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase SPC25 PF06703.6 KNZ80327.1 - 4.9e-38 130.2 0.0 5.6e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) GMC_oxred_N PF00732.14 KNZ80328.1 - 7.5e-32 110.6 0.0 5.3e-31 107.8 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ80328.1 - 1.2e-25 90.5 0.0 2.8e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 KNZ80328.1 - 0.00015 21.7 0.0 0.00088 19.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNZ80328.1 - 0.00037 20.6 0.1 0.16 12.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ80328.1 - 0.00064 19.6 1.0 0.0016 18.3 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KNZ80328.1 - 0.00072 18.5 0.1 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KNZ80328.1 - 0.0021 16.9 0.5 0.0035 16.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KNZ80328.1 - 0.011 14.7 0.1 0.019 13.8 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 KNZ80328.1 - 0.016 14.6 0.4 0.035 13.5 0.3 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 KNZ80328.1 - 0.038 12.4 0.5 0.068 11.6 0.3 1.5 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.13 KNZ80328.1 - 0.047 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KNZ80328.1 - 0.054 12.5 0.1 0.095 11.7 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KNZ80328.1 - 0.092 11.5 0.3 0.17 10.6 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A ABC_tran PF00005.22 KNZ80330.1 - 8.2e-41 139.5 0.0 4.9e-22 78.7 0.0 3.4 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KNZ80330.1 - 7.8e-21 74.6 28.0 2.6e-16 59.8 4.2 4.0 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KNZ80330.1 - 8.7e-07 28.3 0.0 0.0039 16.4 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KNZ80330.1 - 0.031 13.6 0.6 0.62 9.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain Malic_M PF03949.10 KNZ80331.1 - 2e-79 266.7 0.0 2.5e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KNZ80331.1 - 6e-67 224.7 0.0 8.4e-67 224.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain adh_short PF00106.20 KNZ80332.1 - 2e-33 115.6 0.1 2.6e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ80332.1 - 1.9e-26 93.2 0.0 2.8e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ80332.1 - 9.3e-18 64.5 0.1 1.3e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KNZ80332.1 - 0.00016 21.1 0.0 0.00022 20.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ80332.1 - 0.0099 15.8 0.1 0.057 13.4 0.0 2.0 2 1 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KNZ80332.1 - 0.012 15.3 0.2 0.025 14.3 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KNZ80332.1 - 0.021 14.0 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family ADH_N PF08240.7 KNZ80333.1 - 5.6e-28 96.8 0.4 1.1e-27 95.9 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KNZ80333.1 - 1.4e-21 76.4 0.2 2.6e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KNZ80333.1 - 5e-05 24.1 0.1 0.00011 23.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KNZ80333.1 - 0.0038 16.8 0.1 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain PrmA PF06325.8 KNZ80333.1 - 0.04 13.0 0.2 0.066 12.3 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 2-Hacid_dh_C PF02826.14 KNZ80333.1 - 0.041 13.0 0.0 0.088 11.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 KNZ80333.1 - 0.054 13.9 0.0 0.13 12.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 KNZ80333.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 KNZ80333.1 - 0.079 13.5 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain YdfZ PF14001.1 KNZ80333.1 - 2 8.7 4.3 3.3 8.0 0.0 3.1 4 0 0 4 4 4 0 YdfZ protein Dus PF01207.12 KNZ80334.1 - 2e-55 187.7 0.0 4.1e-55 186.7 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) IMPDH PF00478.20 KNZ80334.1 - 0.021 13.7 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KNZ80334.1 - 0.049 12.8 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein GRAB PF10375.4 KNZ80336.1 - 7.2e-05 22.2 0.2 0.0002 20.8 0.1 1.8 1 0 0 1 1 1 1 GRIP-related Arf-binding domain LPP PF04728.8 KNZ80336.1 - 0.0018 18.0 1.4 0.0053 16.5 0.2 2.2 2 0 0 2 2 2 1 Lipoprotein leucine-zipper KLRAQ PF10205.4 KNZ80336.1 - 0.0072 16.3 6.4 0.0072 16.3 4.5 3.5 1 1 2 3 3 3 1 Predicted coiled-coil domain-containing protein Tropomyosin_1 PF12718.2 KNZ80336.1 - 0.71 9.7 49.2 0.53 10.1 16.8 2.9 1 1 2 3 3 3 0 Tropomyosin like DUF1054 PF06335.7 KNZ80336.1 - 0.83 9.2 8.3 0.09 12.4 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1054) GldM_N PF12081.3 KNZ80336.1 - 0.84 9.1 17.0 2 7.9 4.1 2.3 1 1 1 2 2 2 0 GldM N-terminal domain F-box-like PF12937.2 KNZ80337.1 - 0.00011 21.8 0.1 0.00027 20.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like Herpes_Helicase PF02689.9 KNZ80338.1 - 8.7e-05 20.4 0.0 8.7e-05 20.4 0.0 1.0 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 KNZ80339.1 - 1.8e-26 92.9 0.0 1.9e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Viral_helicase1 PF01443.13 KNZ80339.1 - 0.0011 18.5 0.0 0.0013 18.3 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 KNZ80339.1 - 0.045 12.9 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.1 KNZ80339.1 - 0.058 14.2 0.0 0.063 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KNZ80339.1 - 0.13 12.4 0.1 0.16 12.1 0.1 1.5 1 1 0 1 1 1 0 RNA helicase RRM_1 PF00076.17 KNZ80340.1 - 6.9e-38 128.1 0.0 4.5e-21 74.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ80340.1 - 8.3e-28 96.1 0.0 6.3e-14 51.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ80340.1 - 4.2e-11 42.5 0.0 9.2e-07 28.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_1 PF00583.19 KNZ80340.1 - 0.075 13.0 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Histone PF00125.19 KNZ80341.1 - 2.7e-26 91.4 0.0 3.5e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KNZ80341.1 - 3.2e-06 27.0 0.0 5.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KNZ80342.1 - 2e-21 75.8 0.2 2.9e-21 75.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KNZ80342.1 - 1.2e-05 25.2 0.1 3.4e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KNZ80342.1 - 0.00024 21.3 0.0 0.00046 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 KNZ80342.1 - 0.035 14.6 0.4 0.047 14.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.6 KNZ80342.1 - 0.081 12.2 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein DUF601 PF04642.7 KNZ80342.1 - 8.3 5.6 12.2 9.4 5.5 8.4 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF601 zf-C2H2 PF00096.21 KNZ80344.1 - 3.8e-08 33.2 8.5 0.00032 20.8 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ80344.1 - 9.3e-08 31.8 9.8 0.00068 19.7 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KNZ80344.1 - 0.00015 21.8 0.1 0.00045 20.3 0.0 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KNZ80344.1 - 0.001 19.1 6.2 0.053 13.7 0.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 KNZ80344.1 - 0.0023 18.0 3.4 0.52 10.4 0.1 2.3 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 KNZ80344.1 - 0.0035 17.5 12.8 0.099 12.9 0.5 3.6 3 1 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.7 KNZ80344.1 - 0.011 15.7 3.2 2.8 8.1 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KNZ80344.1 - 0.13 12.4 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding HECT PF00632.20 KNZ80345.1 - 4.9e-89 298.6 0.0 7.1e-89 298.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF1024 PF06260.7 KNZ80346.1 - 0.93 9.6 3.3 6.1 7.0 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1024) DUF3245 PF11595.3 KNZ80347.1 - 0.034 14.4 2.0 0.072 13.3 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) DUF1049 PF06305.6 KNZ80347.1 - 0.14 11.6 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Herpes_gE PF02480.11 KNZ80347.1 - 0.45 8.7 2.4 0.74 8.0 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Shisa PF13908.1 KNZ80347.1 - 0.81 9.8 0.0 0.81 9.8 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator OppC_N PF12911.2 KNZ80347.1 - 6 6.3 8.9 22 4.4 6.1 1.9 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C TMEM154 PF15102.1 KNZ80347.1 - 9.7 5.8 7.9 0.3 10.8 0.3 2.2 2 1 0 2 2 2 0 TMEM154 protein family ubiquitin PF00240.18 KNZ80348.1 - 1.5e-18 65.9 0.0 2.6e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KNZ80348.1 - 4.7e-09 35.8 2.4 1.1e-08 34.5 0.2 2.4 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 KNZ80348.1 - 7e-09 35.2 0.1 1.1e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KNZ80348.1 - 5.5e-05 23.2 0.1 0.00022 21.3 0.1 1.9 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KNZ80348.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Herpes_capsid PF06112.6 KNZ80348.1 - 7.4 6.6 13.2 6 6.8 2.1 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Aldo_ket_red PF00248.16 KNZ80349.1 - 9.5e-50 169.0 0.0 1.1e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF706 PF05153.10 KNZ80351.1 - 5.6e-130 432.1 0.4 6.8e-130 431.8 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 KNZ80351.1 - 0.0045 16.9 0.1 0.041 13.9 0.0 2.2 2 0 0 2 2 2 1 HD domain HDOD PF08668.7 KNZ80351.1 - 0.17 11.1 0.0 0.41 9.8 0.0 1.6 1 1 0 1 1 1 0 HDOD domain HAD PF12710.2 KNZ80352.1 - 1.1e-15 58.2 0.0 1.5e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KNZ80352.1 - 4.2e-08 33.6 0.0 5.5e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KNZ80352.1 - 1.6e-05 24.1 0.0 4.6e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.21 KNZ80352.1 - 3.5e-05 24.3 0.0 0.00092 19.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KNZ80352.1 - 0.00037 19.9 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Lactamase_B_2 PF12706.2 KNZ80352.1 - 0.083 12.4 0.0 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain AIG2_2 PF13772.1 KNZ80354.1 - 2.6e-10 40.2 0.1 3.8e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 KNZ80354.1 - 2.9e-08 34.1 0.0 4.1e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family GPI2 PF06432.6 KNZ80355.1 - 1.6e-45 155.6 17.8 1.7e-45 155.5 12.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Proteasome PF00227.21 KNZ80356.1 - 2.9e-51 173.4 0.1 3.7e-51 173.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit AA_permease PF00324.16 KNZ80357.1 - 2.5e-107 359.1 31.6 3e-107 358.9 21.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KNZ80357.1 - 1.9e-20 72.8 34.7 2.5e-20 72.4 24.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 KNZ80357.1 - 0.9 9.2 10.9 0.034 13.8 1.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) LIM PF00412.17 KNZ80358.1 - 3.4e-13 49.4 25.0 0.00023 21.1 2.3 5.0 5 0 0 5 5 5 4 LIM domain Vps39_2 PF10367.4 KNZ80358.1 - 1.8 8.7 7.5 0.12 12.5 0.8 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 RdRP PF05183.7 KNZ80359.1 - 2.7e-129 432.4 0.0 3.7e-129 432.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase CTP_transf_2 PF01467.21 KNZ80359.1 - 2.7e-11 43.7 0.0 4.5e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase DUF1967 PF09269.6 KNZ80359.1 - 0.1 12.2 0.3 18 5.0 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) Transket_pyr PF02779.19 KNZ80360.1 - 1.7e-40 138.3 0.0 2.5e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KNZ80360.1 - 1e-27 96.5 0.0 9e-27 93.4 0.0 2.4 2 1 0 2 2 2 1 Transketolase, C-terminal domain WD40 PF00400.27 KNZ80361.1 - 2.3e-11 43.0 12.6 0.00055 19.7 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KNZ80361.1 - 0.0062 14.8 0.0 0.021 13.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome D1 heme domain Apc15p PF05841.6 KNZ80362.1 - 0.1 13.3 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 Apc15p protein NOA36 PF06524.7 KNZ80362.1 - 3.3 6.8 9.4 4.1 6.5 6.5 1.1 1 0 0 1 1 1 0 NOA36 protein MTHFR PF02219.12 KNZ80363.1 - 2.6e-100 335.2 0.0 1.2e-99 333.0 0.0 1.8 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase PBP PF01161.15 KNZ80363.1 - 0.0093 15.8 0.0 0.037 13.8 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein CRM1_C PF08767.6 KNZ80363.1 - 0.13 11.1 0.1 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 CRM1 C terminal Ras PF00071.17 KNZ80364.1 - 1.5e-59 199.9 0.4 1.9e-59 199.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ80364.1 - 1.2e-22 80.6 0.2 2.3e-22 79.7 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KNZ80364.1 - 2.4e-16 59.4 0.1 3e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KNZ80364.1 - 1.5e-07 31.0 0.3 1.1e-06 28.2 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KNZ80364.1 - 3.6e-07 29.5 0.5 4.6e-07 29.2 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KNZ80364.1 - 4.1e-07 29.3 0.2 7.2e-07 28.5 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KNZ80364.1 - 3.5e-06 26.9 0.1 1.9e-05 24.6 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KNZ80364.1 - 0.0003 20.0 0.5 0.014 14.6 0.4 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 KNZ80364.1 - 0.005 16.5 0.0 0.014 15.0 0.0 1.6 1 1 1 2 2 2 1 Archaeal ATPase Dynamin_N PF00350.18 KNZ80364.1 - 0.0058 16.4 0.1 0.83 9.4 0.0 2.6 2 1 0 2 2 2 1 Dynamin family MobB PF03205.9 KNZ80364.1 - 0.027 14.1 0.2 4.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KNZ80364.1 - 0.031 13.7 1.5 0.25 10.8 1.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 KNZ80364.1 - 0.032 14.1 0.6 0.091 12.6 0.3 1.9 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 KNZ80364.1 - 0.044 13.9 0.0 1.1 9.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain CPT PF07931.7 KNZ80364.1 - 0.052 13.1 0.1 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TAP42 PF04177.7 KNZ80365.1 - 6.8e-71 238.9 0.7 7.8e-71 238.7 0.5 1.0 1 0 0 1 1 1 1 TAP42-like family Orbi_NS3 PF01616.11 KNZ80365.1 - 0.19 10.7 0.5 0.4 9.6 0.3 1.4 1 0 0 1 1 1 0 Orbivirus NS3 PI3_PI4_kinase PF00454.22 KNZ80366.1 - 1e-35 123.3 0.0 5.3e-35 120.9 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KNZ80366.1 - 9.3e-23 80.3 0.1 3.4e-22 78.5 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Peptidase_M28 PF04389.12 KNZ80367.1 - 4.5e-32 111.2 0.0 7.3e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Sybindin PF04099.7 KNZ80368.1 - 1e-38 132.2 0.0 1.3e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KNZ80368.1 - 3.6e-10 39.8 0.0 3.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region HORMA PF02301.13 KNZ80369.1 - 6.6e-46 156.4 0.0 1.2e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 KNZ80369.1 - 0.0031 17.1 9.9 0.0051 16.4 6.9 1.4 1 0 0 1 1 1 1 PHD-finger PFU PF09070.6 KNZ80370.1 - 2.6e-42 143.4 0.1 5.6e-42 142.4 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KNZ80370.1 - 5.4e-36 121.1 15.8 2.3e-08 33.5 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PUL PF08324.6 KNZ80370.1 - 4.1e-30 104.4 0.2 5.9e-30 103.9 0.1 1.3 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 KNZ80370.1 - 0.0001 22.0 0.0 0.25 11.1 0.0 2.9 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Pex14_N PF04695.8 KNZ80370.1 - 0.059 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region His_Phos_1 PF00300.17 KNZ80371.1 - 4.2e-26 91.9 0.0 8.8e-26 90.8 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LysR_substrate PF03466.15 KNZ80371.1 - 0.022 13.8 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain Na_Ca_ex PF01699.19 KNZ80372.1 - 1.3e-45 154.4 25.5 6.1e-25 87.4 7.0 2.5 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.7 KNZ80372.1 - 0.035 13.9 0.3 0.035 13.9 0.2 2.6 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Neurensin PF14927.1 KNZ80372.1 - 0.17 11.2 1.9 2 7.7 0.0 3.1 1 1 0 2 2 2 0 Neurensin Asparaginase PF00710.15 KNZ80374.1 - 1.1e-110 369.4 0.0 2.3e-110 368.3 0.0 1.5 2 0 0 2 2 2 1 Asparaginase Ank PF00023.25 KNZ80374.1 - 3.5e-15 54.9 1.7 1.7e-07 30.7 0.6 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KNZ80374.1 - 5e-13 49.1 0.2 1.1e-12 48.1 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KNZ80374.1 - 2.8e-12 45.6 0.3 5.4e-06 26.1 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KNZ80374.1 - 1.4e-10 41.0 1.5 1.7e-06 28.1 0.4 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KNZ80374.1 - 2.6e-07 30.9 0.0 0.0021 18.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Trp_syntA PF00290.15 KNZ80375.1 - 3.7e-77 258.3 1.0 6.6e-76 254.2 0.7 2.1 1 1 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KNZ80375.1 - 8.8e-42 143.3 0.3 1.5e-41 142.6 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 KNZ80375.1 - 6.2e-05 22.3 0.1 0.00015 21.1 0.1 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.10 KNZ80375.1 - 0.0099 15.0 0.3 0.017 14.3 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase PcrB PF01884.12 KNZ80375.1 - 0.047 12.9 0.1 0.13 11.5 0.1 1.7 2 0 0 2 2 2 0 PcrB family Response_reg PF00072.19 KNZ80375.1 - 0.053 13.5 0.0 0.45 10.5 0.0 2.5 3 0 0 3 3 3 0 Response regulator receiver domain ThiG PF05690.9 KNZ80375.1 - 0.06 12.4 0.2 0.19 10.7 0.2 1.8 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PA PF02225.17 KNZ80375.1 - 0.062 12.9 0.2 3.3 7.4 0.0 3.2 3 0 0 3 3 3 0 PA domain IF-2B PF01008.12 KNZ80376.1 - 3.5e-67 226.3 0.0 4.7e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family GTP_EFTU PF00009.22 KNZ80377.1 - 3.2e-46 157.1 0.1 5e-46 156.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KNZ80377.1 - 8.8e-38 128.5 0.9 6.7e-34 116.0 0.3 2.6 2 0 0 2 2 2 2 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KNZ80377.1 - 4.1e-18 65.0 0.0 8.5e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KNZ80377.1 - 1e-08 35.1 0.0 2.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KNZ80377.1 - 3.9e-05 23.3 0.0 0.0001 22.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KNZ80377.1 - 6.1e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KNZ80377.1 - 0.00014 21.2 0.0 0.00034 20.0 0.0 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KNZ80377.1 - 0.013 14.6 0.2 0.032 13.4 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KNZ80377.1 - 0.015 14.5 0.0 0.053 12.8 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 KNZ80377.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KNZ80377.1 - 0.07 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Asp_protease_2 PF13650.1 KNZ80378.1 - 0.003 18.0 0.0 0.013 16.0 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease NSP10 PF09401.5 KNZ80378.1 - 0.11 12.2 0.0 0.58 9.9 0.0 2.1 2 0 0 2 2 2 0 RNA synthesis protein NSP10 DUF3246 PF11596.3 KNZ80380.1 - 0.27 10.4 6.5 0.61 9.3 0.5 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3246) Retrotrans_gag PF03732.12 KNZ80382.1 - 0.0026 17.8 0.1 0.0036 17.3 0.1 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein p450 PF00067.17 KNZ80387.1 - 1.1e-64 218.7 0.0 1.3e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4085 PF13315.1 KNZ80388.1 - 0.037 13.3 0.2 0.063 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) SSF PF00474.12 KNZ80389.1 - 1.9e-21 76.1 26.2 1.8e-20 72.9 18.1 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family adh_short PF00106.20 KNZ80391.1 - 1.1e-19 70.9 3.8 6.9e-17 61.8 0.6 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ80391.1 - 4.4e-06 26.6 0.2 1.6e-05 24.7 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ80391.1 - 9.2e-06 25.4 0.6 4.7e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.13 KNZ80391.1 - 0.00088 18.9 0.1 0.0015 18.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 KNZ80391.1 - 0.004 16.6 0.1 0.01 15.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HCV_NS5a_1b PF08301.8 KNZ80391.1 - 0.064 13.6 0.0 0.2 12.0 0.0 1.8 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a domain 1b p450 PF00067.17 KNZ80392.1 - 1.2e-50 172.3 0.0 1.8e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 COX1 PF00115.15 KNZ80393.1 - 0.02 13.5 4.3 0.014 14.0 1.1 1.8 2 0 0 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I Solute_trans_a PF03619.11 KNZ80394.1 - 4.4e-97 324.6 8.1 5.3e-97 324.4 5.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Redoxin PF08534.5 KNZ80395.1 - 9.6e-38 129.0 0.0 1.1e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KNZ80395.1 - 9e-13 47.9 0.0 9.2e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family MFS_1 PF07690.11 KNZ80396.1 - 2e-42 145.2 27.1 2e-42 145.2 18.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ80396.1 - 1.1e-18 67.1 3.1 1.1e-18 67.1 2.1 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter ABC_tran PF00005.22 KNZ80397.1 - 2.6e-22 79.6 0.0 5.2e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KNZ80397.1 - 3.6e-09 36.9 0.1 0.00036 20.6 0.0 2.7 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 KNZ80397.1 - 2.5e-06 26.8 0.4 0.052 12.7 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KNZ80397.1 - 0.00016 20.9 0.6 0.00034 19.8 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KNZ80397.1 - 0.00031 20.8 0.0 0.013 15.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KNZ80397.1 - 0.00043 19.7 0.2 0.001 18.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KNZ80397.1 - 0.00048 20.9 0.3 0.0012 19.6 0.1 1.9 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 KNZ80397.1 - 0.003 16.5 0.3 0.0065 15.4 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.1 KNZ80397.1 - 0.0033 17.7 0.2 0.0063 16.8 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ80397.1 - 0.0037 17.2 0.0 0.0083 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.1 KNZ80397.1 - 0.0061 15.6 0.0 0.046 12.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KNZ80397.1 - 0.0075 16.1 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KNZ80397.1 - 0.011 15.6 0.0 0.11 12.3 0.0 2.5 3 0 0 3 3 2 0 AAA domain ABC_ATPase PF09818.4 KNZ80397.1 - 0.011 14.3 0.1 0.25 9.8 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_10 PF12846.2 KNZ80397.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain Miro PF08477.8 KNZ80397.1 - 0.02 15.4 0.0 0.048 14.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 KNZ80397.1 - 0.026 14.4 0.0 0.069 13.1 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 KNZ80397.1 - 0.027 14.1 0.3 0.066 12.9 0.1 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KNZ80397.1 - 0.033 13.8 0.3 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 KNZ80397.1 - 0.035 14.0 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KNZ80397.1 - 0.042 13.5 0.3 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain SRPRB PF09439.5 KNZ80397.1 - 0.047 12.9 0.1 6.8 5.8 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.7 KNZ80397.1 - 0.056 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 KNZ80397.1 - 0.067 12.0 0.1 0.25 10.1 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.1 KNZ80397.1 - 0.096 12.9 0.1 0.31 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain Septin PF00735.13 KNZ80397.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin Meth_synt_1 PF08267.7 KNZ80397.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain AAA_25 PF13481.1 KNZ80397.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KNZ80397.1 - 0.17 11.4 0.1 0.3 10.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain Ndc1_Nup PF09531.5 KNZ80398.1 - 6.5e-52 176.7 4.4 7.6e-52 176.5 3.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Silic_transp PF03842.8 KNZ80398.1 - 0.0034 15.5 1.6 0.0048 15.0 1.1 1.2 1 0 0 1 1 1 1 Silicon transporter MFS_1 PF07690.11 KNZ80400.1 - 9.6e-44 149.5 35.5 9.6e-44 149.5 24.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ80400.1 - 6.4e-17 61.2 10.6 6.4e-17 61.2 7.4 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KNZ80400.1 - 6.1e-06 24.7 6.5 6.1e-06 24.7 4.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-RING_2 PF13639.1 KNZ80403.1 - 5.2e-10 38.9 11.3 8.4e-10 38.3 7.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KNZ80403.1 - 2.1e-05 24.0 10.8 3.3e-05 23.4 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KNZ80403.1 - 7.5e-05 22.7 9.0 0.00019 21.4 6.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KNZ80403.1 - 0.00011 21.9 2.4 0.00018 21.2 1.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KNZ80403.1 - 0.00084 19.0 9.0 0.0015 18.2 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KNZ80403.1 - 0.00094 19.1 11.9 0.0015 18.4 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNZ80403.1 - 0.0016 18.1 7.0 0.0029 17.2 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KNZ80403.1 - 0.0025 17.4 5.1 0.0042 16.7 3.5 1.4 1 0 0 1 1 1 1 PHD-finger Rtf2 PF04641.7 KNZ80403.1 - 0.016 14.4 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 KNZ80403.1 - 0.26 11.2 8.0 0.73 9.7 5.5 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Tim54 PF11711.3 KNZ80403.1 - 1.1 7.7 3.9 1.4 7.4 2.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 zf-RING_UBOX PF13445.1 KNZ80403.1 - 2.1 8.1 6.4 4.1 7.2 4.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Nop14 PF04147.7 KNZ80403.1 - 9.1 4.0 8.5 11 3.7 5.9 1.0 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_11 PF00457.12 KNZ80404.1 - 7.6e-71 237.2 17.2 8.8e-71 237.0 11.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Peptidase_S8 PF00082.17 KNZ80405.1 - 2.9e-33 115.2 2.1 4.4e-33 114.6 1.4 1.2 1 0 0 1 1 1 1 Subtilase family RVT_1 PF00078.22 KNZ80406.1 - 0.03 13.6 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SAP30_Sin3_bdg PF13867.1 KNZ80406.1 - 0.067 13.0 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 KNTase_C PF07827.6 KNZ80406.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 KNTase C-terminal domain DUF1769 PF08588.5 KNZ80408.1 - 1.9e-14 53.3 0.1 6.1e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) Sugar_tr PF00083.19 KNZ80409.1 - 3.2e-87 292.9 13.8 3.7e-87 292.7 9.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ80409.1 - 2.1e-18 66.1 28.6 1.7e-13 50.0 10.0 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.15 KNZ80409.1 - 0.00091 17.3 3.4 0.0023 16.0 0.1 2.2 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Dala_Dala_lig_N PF01820.16 KNZ80409.1 - 0.074 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus zf-MYND PF01753.13 KNZ80410.1 - 4e-06 26.6 14.9 6.5e-06 25.9 10.3 1.3 1 0 0 1 1 1 1 MYND finger Fungal_trans PF04082.13 KNZ80411.1 - 2.5e-15 56.0 3.2 5.1e-15 55.0 2.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3446 PF11928.3 KNZ80411.1 - 0.56 10.4 9.5 1.4 9.1 6.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Lipoprotein_7 PF01540.11 KNZ80413.1 - 0.0087 15.1 4.8 0.011 14.8 3.4 1.1 1 0 0 1 1 1 1 Adhesin lipoprotein TFIID-18kDa PF02269.11 KNZ80413.1 - 0.12 12.1 0.5 0.26 11.1 0.4 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit zf-CSL PF05207.8 KNZ80414.1 - 9.4e-23 79.4 0.4 9.4e-23 79.4 0.3 1.8 2 1 0 2 2 2 1 CSL zinc finger DUF688 PF05097.7 KNZ80414.1 - 0.03 13.2 1.0 0.03 13.2 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Zn-ribbon_8 PF09723.5 KNZ80414.1 - 0.036 14.0 1.5 0.078 12.9 1.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 KNZ80414.1 - 0.077 12.5 0.5 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Nucleoplasmin PF03066.10 KNZ80414.1 - 0.13 11.7 4.8 0.14 11.6 3.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin Paf1 PF03985.8 KNZ80414.1 - 0.14 10.8 5.3 0.18 10.4 3.6 1.1 1 0 0 1 1 1 0 Paf1 zinc_ribbon_4 PF13717.1 KNZ80414.1 - 0.2 11.3 0.7 0.33 10.6 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain TRAP_alpha PF03896.11 KNZ80414.1 - 0.31 9.9 6.7 0.36 9.7 4.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Lar_restr_allev PF14354.1 KNZ80414.1 - 0.32 11.3 2.2 0.93 9.8 1.5 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar CDC45 PF02724.9 KNZ80414.1 - 0.87 7.5 4.9 0.89 7.5 3.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 KNZ80414.1 - 4.3 5.9 13.2 4.9 5.7 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIE-A_C-term PF11521.3 KNZ80414.1 - 8.4 6.4 12.2 17 5.4 7.9 1.8 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Mito_carr PF00153.22 KNZ80415.1 - 1.3e-18 66.4 11.1 4.1e-09 36.0 0.2 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein TPR_11 PF13414.1 KNZ80416.1 - 6.5e-46 153.8 15.5 7e-15 54.4 0.0 7.3 2 2 6 9 9 9 8 TPR repeat TPR_1 PF00515.23 KNZ80416.1 - 2.5e-35 118.6 7.8 1.2e-05 24.7 0.0 11.4 10 1 1 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ80416.1 - 1.1e-31 106.1 14.7 0.00054 19.6 0.0 10.9 11 1 1 12 12 12 6 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ80416.1 - 9.4e-19 67.5 24.1 1.3e-06 28.9 0.0 7.7 5 3 2 9 9 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ80416.1 - 7.9e-18 63.1 3.6 0.015 15.4 0.0 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ80416.1 - 2.2e-15 56.3 15.1 4.5e-05 23.3 0.0 7.5 3 3 5 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ80416.1 - 2e-14 52.1 5.2 0.11 12.3 0.0 7.5 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ80416.1 - 3.2e-14 51.5 5.7 0.014 15.1 0.0 8.0 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ80416.1 - 4.6e-12 45.4 16.7 0.0088 16.5 0.0 8.5 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ80416.1 - 6.9e-12 45.5 11.3 0.0016 18.7 0.0 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ80416.1 - 1.8e-11 43.7 6.4 0.00014 21.6 0.0 6.1 5 1 2 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KNZ80416.1 - 1.7e-10 40.8 12.1 0.0065 16.5 0.0 5.3 4 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KNZ80416.1 - 3.2e-05 24.1 17.8 0.46 11.0 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat DUF3856 PF12968.2 KNZ80416.1 - 9.2e-05 22.2 4.0 0.3 10.8 0.0 5.0 5 1 1 6 6 6 1 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.4 KNZ80416.1 - 0.0039 16.4 2.7 8.7 5.6 0.0 4.4 4 0 0 4 4 4 0 SHNi-TPR Apc5 PF12862.2 KNZ80416.1 - 0.1 12.4 0.1 0.1 12.4 0.0 3.4 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 5 RPN7 PF10602.4 KNZ80416.1 - 9.9 5.5 9.3 1.4 8.2 0.1 3.6 4 1 0 4 4 4 0 26S proteasome subunit RPN7 Glyco_hydro_43 PF04616.9 KNZ80417.1 - 9.1e-77 257.9 1.0 1.2e-76 257.5 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF2813 PF11398.3 KNZ80418.1 - 0.001 18.2 0.2 0.0015 17.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) LRR_8 PF13855.1 KNZ80418.1 - 0.73 9.6 7.4 1.1 9.0 1.1 3.1 3 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 KNZ80418.1 - 4.4 7.0 11.5 1.4 8.6 0.9 4.0 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) DUF3712 PF12505.3 KNZ80419.1 - 1.5e-109 360.9 55.4 1e-23 83.7 0.1 9.2 9 0 0 9 9 9 6 Protein of unknown function (DUF3712) LEA_2 PF03168.8 KNZ80419.1 - 2.2e-13 50.4 27.6 0.0061 16.9 0.0 9.5 10 0 0 10 10 10 5 Late embryogenesis abundant protein Bactofilin PF04519.8 KNZ80419.1 - 0.0017 18.3 0.0 0.008 16.1 0.0 2.2 1 0 0 1 1 1 1 Polymer-forming cytoskeletal MCE PF02470.15 KNZ80419.1 - 0.0071 16.3 0.0 0.18 11.7 0.0 3.3 3 0 0 3 3 3 1 mce related protein DUF3684 PF12449.3 KNZ80421.1 - 0 1103.4 0.0 0 1103.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 KNZ80421.1 - 0.0013 18.4 0.0 0.0081 15.8 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L31e PF01198.14 KNZ80421.1 - 0.022 14.4 0.0 0.09 12.4 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L31e HATPase_c PF02518.21 KNZ80421.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Chitin_synth_2 PF03142.10 KNZ80422.1 - 1.4e-246 819.0 0.0 1.7e-246 818.7 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KNZ80422.1 - 3.5e-17 62.7 13.8 4.4e-17 62.4 5.8 3.4 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KNZ80422.1 - 2.4e-16 60.2 0.1 1.3e-14 54.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KNZ80422.1 - 3.8e-08 33.0 0.0 5.1e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 KNZ80422.1 - 1.7e-06 27.4 0.0 7.3e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KNZ80422.1 - 0.04 13.6 0.0 0.77 9.4 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 TPR_11 PF13414.1 KNZ80423.1 - 8.1e-48 159.9 43.2 2.5e-12 46.2 0.4 13.9 10 4 5 16 16 16 11 TPR repeat TPR_16 PF13432.1 KNZ80423.1 - 5.1e-42 141.6 57.7 2.7e-09 37.4 2.7 13.8 9 4 6 15 15 15 11 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ80423.1 - 1.5e-32 109.8 14.1 2.4e-06 26.8 0.0 12.9 13 1 0 13 13 13 7 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ80423.1 - 3.3e-32 108.0 49.0 0.00014 22.2 0.1 16.3 10 5 5 15 15 15 8 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ80423.1 - 1.5e-29 99.4 41.5 3.3e-05 23.4 0.0 16.9 20 0 0 20 20 18 9 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ80423.1 - 2.9e-29 101.1 37.9 0.00049 20.3 0.1 12.4 9 3 2 12 12 12 8 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ80423.1 - 8.6e-27 91.0 28.9 0.02 15.0 0.0 16.8 18 0 0 18 18 16 6 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ80423.1 - 1.7e-23 82.3 36.0 0.00015 21.6 0.1 10.8 6 4 3 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ80423.1 - 7.2e-19 66.1 13.3 0.025 14.3 0.0 13.8 16 0 0 16 16 14 4 Tetratricopeptide repeat Apc3 PF12895.2 KNZ80423.1 - 1.2e-18 66.9 13.8 2.1e-09 37.3 0.0 7.6 8 1 0 8 8 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KNZ80423.1 - 3.3e-11 42.0 22.4 0.069 12.9 0.0 11.8 14 1 1 15 15 13 3 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ80423.1 - 6.7e-10 38.6 36.1 0.0021 17.8 0.0 10.6 12 1 0 12 12 11 4 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ80423.1 - 2.5e-08 33.8 14.9 0.21 12.1 0.0 11.1 13 0 0 13 13 10 1 Tetratricopeptide repeat DSPc PF00782.15 KNZ80423.1 - 2.2e-05 24.0 0.0 6.8e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 KNZ80423.1 - 0.0002 20.8 0.1 0.0011 18.4 0.0 2.0 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) TPR_21 PF09976.4 KNZ80423.1 - 0.005 16.7 15.6 0.09 12.7 1.1 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 KNZ80423.1 - 0.0077 16.3 17.1 2.4 8.3 0.0 8.7 8 3 2 10 10 9 2 Tetratricopeptide repeat NARP1 PF12569.3 KNZ80423.1 - 0.014 14.1 6.7 0.34 9.5 0.0 4.0 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 Y_phosphatase PF00102.22 KNZ80423.1 - 0.057 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF4398 PF14346.1 KNZ80423.1 - 0.1 12.6 3.7 0.11 12.5 0.1 3.0 3 0 0 3 3 2 0 Domain of unknown function (DUF4398) ChAPs PF09295.5 KNZ80423.1 - 0.16 10.6 7.1 0.46 9.1 0.2 4.4 5 1 1 6 6 6 0 ChAPs (Chs5p-Arf1p-binding proteins) LETM1 PF07766.8 KNZ80424.1 - 1.6e-23 83.1 1.2 5.2e-11 42.0 0.1 2.1 1 1 1 2 2 2 2 LETM1-like protein KfrA_N PF11740.3 KNZ80425.1 - 0.01 16.3 2.9 0.3 11.5 0.3 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF3401 PF11881.3 KNZ80426.1 - 0.013 14.8 1.2 0.026 13.9 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3401) DOCK-C2 PF14429.1 KNZ80427.1 - 1.4e-40 138.9 0.0 4.3e-40 137.3 0.0 1.9 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KNZ80427.1 - 3.8e-37 127.2 0.5 7e-37 126.4 0.3 1.5 1 0 0 1 1 1 1 Dedicator of cytokinesis DASH_Spc34 PF08657.5 KNZ80428.1 - 5.4e-06 26.2 3.6 0.0031 17.2 2.5 3.4 1 1 0 1 1 1 1 DASH complex subunit Spc34 Fmp27_WPPW PF10359.4 KNZ80428.1 - 0.0015 17.0 0.7 0.0019 16.6 0.5 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain IncA PF04156.9 KNZ80428.1 - 0.12 11.9 1.6 0.25 10.9 1.1 1.4 1 0 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 KNZ80428.1 - 0.14 12.1 0.8 0.35 10.9 0.6 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SlyX PF04102.7 KNZ80428.1 - 1.3 9.4 5.1 3.3 8.1 0.2 3.1 2 1 1 3 3 3 0 SlyX APG5 PF04106.7 KNZ80429.1 - 1.5e-44 151.8 0.0 1.9e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 AMP-binding PF00501.23 KNZ80430.1 - 9.4e-16 57.2 0.0 1.3e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Dfp1_Him1_M PF08630.5 KNZ80431.1 - 3.7e-22 78.4 0.0 9.2e-22 77.1 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KNZ80431.1 - 1.9e-16 59.4 0.5 4.6e-16 58.2 0.4 1.7 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 KNZ80431.1 - 1.3e-05 25.2 0.1 3.1e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KNZ80431.1 - 0.00033 20.4 0.0 0.00091 19.0 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain TROVE PF05731.6 KNZ80431.1 - 0.23 10.1 7.1 0.32 9.7 1.9 2.4 2 0 0 2 2 2 0 TROVE domain HK97-gp10_like PF04883.7 KNZ80431.1 - 0.59 11.1 3.5 0.29 12.0 0.2 2.2 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component Zn_clus PF00172.13 KNZ80433.1 - 0.18 11.7 12.5 0.097 12.6 3.5 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PP2C PF00481.16 KNZ80434.1 - 8.2e-22 77.8 0.0 1.5e-21 76.9 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C DUF2267 PF10025.4 KNZ80434.1 - 0.093 12.8 0.0 7.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) SAM_decarbox PF01536.11 KNZ80435.1 - 1.5e-73 247.3 0.0 7.3e-55 185.9 0.0 2.1 2 0 0 2 2 2 2 Adenosylmethionine decarboxylase DUF1279 PF06916.8 KNZ80437.1 - 1.1e-18 67.2 0.0 1.5e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) RPEL PF02755.10 KNZ80438.1 - 0.0067 15.7 1.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 RPEL repeat DUF3510 PF12022.3 KNZ80438.1 - 0.069 13.2 1.4 1.4 9.0 1.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) DUF3436 PF11918.3 KNZ80438.1 - 0.078 13.2 0.9 2.1 8.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3436) Rax2 PF12768.2 KNZ80440.1 - 1.5e-83 280.3 17.8 6.9e-66 222.3 0.6 5.7 5 1 1 6 6 6 4 Cortical protein marker for cell polarity SH3_1 PF00018.23 KNZ80440.1 - 3.9e-10 38.9 0.0 6.9e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Kelch_6 PF13964.1 KNZ80440.1 - 4.7e-10 39.2 14.1 0.49 10.6 0.1 7.7 6 1 1 7 7 7 4 Kelch motif SH3_9 PF14604.1 KNZ80440.1 - 1.9e-08 33.7 0.2 3.9e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Kelch_4 PF13418.1 KNZ80440.1 - 2.3e-05 24.0 22.0 0.098 12.4 0.1 7.6 8 0 0 8 8 8 2 Galactose oxidase, central domain Kelch_1 PF01344.20 KNZ80440.1 - 0.00036 20.0 2.2 22 4.7 0.0 5.8 7 0 0 7 7 7 0 Kelch motif Kelch_3 PF13415.1 KNZ80440.1 - 0.00082 19.4 10.6 0.16 12.1 0.1 6.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Reg_prop PF07494.6 KNZ80440.1 - 0.049 13.6 3.8 3.1 8.1 0.0 5.1 6 0 0 6 6 6 0 Two component regulator propeller PQQ_3 PF13570.1 KNZ80440.1 - 1.2 9.4 11.2 1.1 9.5 0.1 5.2 5 0 0 5 5 5 0 PQQ-like domain zf-C2H2_2 PF12756.2 KNZ80441.1 - 1.1e-33 115.3 9.4 2.9e-31 107.5 0.3 2.8 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KNZ80441.1 - 5.5e-07 29.5 1.9 5.5e-07 29.5 1.3 3.0 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KNZ80441.1 - 2.3e-06 27.5 1.8 2.3e-06 27.5 1.2 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KNZ80441.1 - 0.029 14.2 2.3 0.63 10.0 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF629 PF04780.7 KNZ80441.1 - 0.062 11.8 2.8 4 5.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.1 KNZ80441.1 - 0.15 12.4 9.1 3.3 8.2 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KNZ80441.1 - 0.19 12.1 11.7 0.27 11.6 0.3 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type CLASP_N PF12348.3 KNZ80442.1 - 4.6e-23 81.7 0.0 7.2e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.17 KNZ80442.1 - 0.021 14.8 0.0 0.66 10.2 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat DUF2418 PF10332.4 KNZ80442.1 - 0.056 13.7 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) tRNA-synt_2c PF01411.14 KNZ80443.1 - 2.2e-184 613.8 0.2 8.6e-155 516.1 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KNZ80443.1 - 4.2e-17 61.7 0.1 1.2e-16 60.2 0.1 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KNZ80443.1 - 2.4e-06 27.1 0.8 7.6e-06 25.5 0.2 2.2 2 0 0 2 2 2 1 DHHA1 domain DUF1664 PF07889.7 KNZ80443.1 - 0.0019 18.0 0.2 0.04 13.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Ribosomal_S13 PF00416.17 KNZ80444.1 - 5.1e-36 123.3 0.6 6e-36 123.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KNZ80444.1 - 0.024 13.2 0.0 0.024 13.1 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 KNZ80444.1 - 0.11 12.5 0.4 0.23 11.5 0.3 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 GNAT_acetyltr_2 PF13718.1 KNZ80447.1 - 2e-74 249.2 0.0 3.5e-74 248.3 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KNZ80447.1 - 7.2e-65 217.9 0.0 2.2e-64 216.3 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KNZ80447.1 - 3.3e-38 129.2 0.1 8.7e-38 127.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KNZ80447.1 - 3.1e-33 113.8 0.5 8.9e-33 112.4 0.3 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain SAP PF02037.22 KNZ80447.1 - 0.00064 19.1 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 SAP domain YjeF_N PF03853.10 KNZ80447.1 - 0.0042 16.7 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 2 YjeF-related protein N-terminus Acetyltransf_7 PF13508.1 KNZ80447.1 - 0.043 13.9 0.0 0.37 10.9 0.0 2.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_19 PF13245.1 KNZ80447.1 - 0.047 13.4 0.0 0.34 10.6 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain RVT_1 PF00078.22 KNZ80448.1 - 0.0044 16.4 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2762 PF10960.3 KNZ80449.1 - 0.07 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) rve PF00665.21 KNZ80452.1 - 0.038 14.1 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain SH3_9 PF14604.1 KNZ80455.1 - 4.1e-16 58.2 0.1 8.8e-16 57.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KNZ80455.1 - 1.5e-14 53.0 0.1 4.4e-14 51.5 0.1 1.9 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 KNZ80455.1 - 2.1e-13 50.3 0.0 5.4e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 KNZ80455.1 - 9e-13 47.8 0.0 1.5e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 KNZ80455.1 - 4.3e-10 38.9 0.1 1e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 KNZ80455.1 - 4.2e-09 36.4 0.1 1.6e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 KNZ80455.1 - 0.16 12.2 5.9 0.094 12.9 1.8 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain SGL PF08450.7 KNZ80456.1 - 1e-06 28.3 0.0 1.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Peptidase_C1_2 PF03051.10 KNZ80457.1 - 2.9e-155 517.0 0.0 3.4e-155 516.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KNZ80457.1 - 2.3e-06 27.6 0.1 0.018 14.9 0.0 2.5 2 1 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.8 KNZ80457.1 - 0.022 13.3 0.0 0.038 12.5 0.0 1.3 1 0 0 1 1 1 0 Phage portal protein, lambda family DnaJ PF00226.26 KNZ80459.1 - 2.1e-13 49.7 0.1 3.6e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain TRP PF06011.7 KNZ80460.1 - 1e-69 235.2 30.2 1.5e-69 234.7 20.9 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KNZ80460.1 - 1.4e-26 93.1 0.2 1.4e-26 93.1 0.2 1.7 2 0 0 2 2 2 1 ML-like domain ATP1G1_PLM_MAT8 PF02038.11 KNZ80460.1 - 0.11 11.5 2.0 0.33 10.0 1.4 1.7 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family OSCP PF00213.13 KNZ80461.1 - 1.2e-41 142.4 1.8 1.4e-41 142.2 1.3 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit PEMT PF04191.8 KNZ80462.1 - 7.4e-13 48.5 2.6 2.4e-12 46.8 0.3 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 KNZ80462.1 - 3.5e-12 46.3 0.6 1.1e-10 41.5 0.1 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.7 KNZ80462.1 - 0.00056 19.2 0.0 0.00065 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 KNZ80462.1 - 0.0025 16.4 0.1 0.0032 16.0 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF4083 PF13314.1 KNZ80462.1 - 0.034 13.9 0.5 0.32 10.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) MgsA_C PF12002.3 KNZ80463.1 - 2.6e-54 183.4 0.2 7.6e-54 181.8 0.1 1.7 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KNZ80463.1 - 3.5e-08 33.7 0.2 1.9e-07 31.3 0.1 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KNZ80463.1 - 2.3e-07 30.1 0.0 3.3e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KNZ80463.1 - 0.00033 20.5 0.0 0.0011 18.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KNZ80463.1 - 0.0009 18.7 0.0 0.0022 17.4 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 KNZ80463.1 - 0.026 14.2 0.1 0.13 12.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KNZ80463.1 - 0.042 13.2 0.0 8.9 5.6 0.0 2.9 2 1 1 3 3 3 0 AAA-like domain AAA_22 PF13401.1 KNZ80463.1 - 0.053 13.6 0.9 1.8 8.6 0.2 2.9 2 1 0 2 2 2 0 AAA domain Peptidase_C15 PF01470.12 KNZ80464.1 - 5.3e-10 39.4 0.0 0.00015 21.6 0.0 2.3 2 0 0 2 2 2 2 Pyroglutamyl peptidase APS_kinase PF01583.15 KNZ80465.1 - 1.9e-68 229.0 0.0 2.2e-68 228.8 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 KNZ80465.1 - 3.9e-07 30.0 0.0 5.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ80465.1 - 5.4e-06 27.2 0.1 8.6e-06 26.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KNZ80465.1 - 2.1e-05 24.8 0.0 3.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KNZ80465.1 - 0.00089 18.5 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 KNZ80465.1 - 0.0079 15.7 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KNZ80465.1 - 0.01 14.9 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin CPT PF07931.7 KNZ80465.1 - 0.13 11.8 0.2 0.31 10.6 0.1 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Pkinase PF00069.20 KNZ80466.1 - 8.9e-48 162.6 0.0 1.2e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ80466.1 - 1.4e-34 119.3 0.0 1.9e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ80466.1 - 0.00085 18.3 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KNZ80466.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAP1 PF08601.5 KNZ80466.1 - 0.46 10.1 3.7 0.86 9.2 2.6 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 Hexapep PF00132.19 KNZ80467.1 - 1.7e-10 39.9 0.5 0.0011 18.3 0.0 3.3 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 KNZ80467.1 - 1.2e-07 31.2 0.0 1.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KNZ80467.1 - 1.2e-05 25.4 0.0 1.9e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KNZ80467.1 - 0.021 14.3 4.2 0.053 13.0 1.1 2.4 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Bactofilin PF04519.8 KNZ80467.1 - 0.33 10.9 3.0 0.53 10.3 2.1 1.3 1 0 0 1 1 1 0 Polymer-forming cytoskeletal CAP_GLY PF01302.20 KNZ80468.1 - 3.3e-17 61.9 2.6 5.4e-17 61.2 1.8 1.4 1 0 0 1 1 1 1 CAP-Gly domain IncA PF04156.9 KNZ80468.1 - 0.00026 20.6 97.3 0.0041 16.7 12.6 6.4 2 2 2 6 6 6 4 IncA protein DUF4200 PF13863.1 KNZ80468.1 - 0.0059 16.5 17.1 0.0059 16.5 11.8 7.0 4 2 2 7 7 7 1 Domain of unknown function (DUF4200) Filament PF00038.16 KNZ80468.1 - 0.55 9.6 78.8 1.8 7.9 21.1 4.4 1 1 2 3 3 3 0 Intermediate filament protein zf-CCHC_4 PF14392.1 KNZ80468.1 - 2.8 7.6 9.3 1 9.0 1.2 2.5 2 0 0 2 2 2 0 Zinc knuckle DUF3584 PF12128.3 KNZ80468.1 - 5.4 4.2 76.2 0.084 10.2 28.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) MAD PF05557.8 KNZ80468.1 - 9.4 4.1 78.9 16 3.4 52.1 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein eIF-3c_N PF05470.7 KNZ80470.1 - 4.5e-175 583.1 18.3 2.7e-145 484.8 3.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KNZ80470.1 - 5.6e-16 58.7 0.5 1e-14 54.6 0.0 3.0 3 1 0 3 3 3 1 PCI domain PAP2 PF01569.16 KNZ80471.1 - 5.4e-09 35.8 17.5 4.6e-08 32.8 12.1 2.2 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 KNZ80471.1 - 4.1e-08 32.9 10.3 9.6e-08 31.7 7.2 1.6 1 1 0 1 1 1 1 PAP2 superfamily ODC_AZ PF02100.12 KNZ80472.1 - 5.6e-18 64.4 0.0 8.3e-18 63.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Ribosomal_S5 PF00333.15 KNZ80473.1 - 6.2e-28 96.3 1.5 1.2e-27 95.4 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KNZ80473.1 - 4.6e-21 73.8 0.1 8.4e-21 73.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain p450 PF00067.17 KNZ80474.1 - 3.5e-64 217.0 0.0 1.3e-63 215.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF3419 PF11899.3 KNZ80476.1 - 5.9e-128 426.8 0.0 7.6e-128 426.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_11 PF08241.7 KNZ80476.1 - 0.0017 18.7 0.0 0.34 11.4 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ80476.1 - 0.0019 17.9 0.0 0.0084 15.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNZ80476.1 - 0.0086 15.2 0.0 0.091 11.8 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KNZ80476.1 - 0.032 14.2 0.0 6.4 6.8 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ80476.1 - 0.11 12.9 0.0 4.1 7.9 0.0 3.3 3 1 0 3 3 3 0 Methyltransferase domain KTI12 PF08433.5 KNZ80477.1 - 1.5e-73 247.3 0.0 1.7e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KNZ80477.1 - 7.5e-08 32.3 0.0 5.4e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KNZ80477.1 - 0.045 14.0 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RhoGAP PF00620.22 KNZ80478.1 - 5.4e-42 142.9 0.1 2.3e-41 140.9 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 KNZ80478.1 - 5.2e-14 52.0 15.8 3.1e-07 30.3 4.9 2.7 2 0 0 2 2 2 2 LIM domain C1_1 PF00130.17 KNZ80478.1 - 1.8e-05 24.3 8.0 1.8e-05 24.3 5.5 3.7 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) BTB PF00651.26 KNZ80479.1 - 6.7e-12 45.3 0.0 0.00017 21.5 0.0 2.6 3 0 0 3 3 3 2 BTB/POZ domain Pam16 PF03656.8 KNZ80481.1 - 5.2e-20 71.5 0.7 4e-19 68.6 0.5 2.0 1 1 0 1 1 1 1 Pam16 PALP PF00291.20 KNZ80482.1 - 4.8e-64 216.5 0.2 5.9e-64 216.2 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Arf PF00025.16 KNZ80483.1 - 4.9e-77 257.1 0.0 5.5e-77 256.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KNZ80483.1 - 7.2e-13 48.2 0.0 7.7e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KNZ80483.1 - 1.2e-10 40.9 0.0 1.5e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KNZ80483.1 - 2.6e-10 39.5 1.7 1.4e-06 27.2 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KNZ80483.1 - 9.3e-10 38.0 0.0 1.1e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KNZ80483.1 - 1e-06 29.2 0.0 1.4e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KNZ80483.1 - 0.00033 20.5 0.1 0.00089 19.1 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KNZ80483.1 - 0.014 14.4 0.1 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase L27 PF02828.11 KNZ80483.1 - 0.04 13.5 0.2 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 L27 domain PLA2_B PF01735.13 KNZ80484.1 - 1.4e-98 330.2 0.0 1.8e-98 329.8 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF1049 PF06305.6 KNZ80484.1 - 0.22 11.0 0.8 0.45 10.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) FixQ PF05545.6 KNZ80484.1 - 0.35 10.5 2.0 0.57 9.8 0.4 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ UBA PF00627.26 KNZ80485.1 - 1.5e-22 78.7 5.4 2.8e-12 46.0 0.3 2.8 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.18 KNZ80485.1 - 2.6e-19 68.3 3.0 4.1e-19 67.7 2.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KNZ80485.1 - 2.4e-09 36.7 3.7 5.6e-09 35.5 2.6 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.6 KNZ80485.1 - 2.5e-09 36.4 4.8 4.9e-09 35.5 3.3 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD_2 PF13881.1 KNZ80485.1 - 0.0041 16.9 0.1 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KNZ80485.1 - 0.0048 17.0 0.0 0.0079 16.3 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain WIYLD PF10440.4 KNZ80485.1 - 0.0067 16.3 0.0 2.8 7.9 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-binding WIYLD domain UBA_3 PF09288.5 KNZ80485.1 - 0.0084 15.6 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain CUE PF02845.11 KNZ80485.1 - 0.03 13.8 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 0 CUE domain RRM_1 PF00076.17 KNZ80486.1 - 6.4e-15 54.5 0.0 1e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ80486.1 - 9.5e-15 54.3 0.0 1.6e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ80486.1 - 3.3e-10 39.6 0.0 4.8e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_4 PF12799.2 KNZ80487.1 - 5.2e-15 54.6 17.2 7.3e-06 25.4 1.5 5.7 3 1 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNZ80487.1 - 2.3e-14 52.8 11.1 2.8e-10 39.7 2.4 3.8 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KNZ80487.1 - 4.9e-08 31.9 10.7 0.26 11.4 0.1 6.7 4 2 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 KNZ80487.1 - 0.013 15.5 9.9 13 6.2 0.7 5.2 4 1 0 4 4 4 0 Leucine Rich repeat Phage_GPL PF05926.6 KNZ80487.1 - 0.052 13.3 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 Phage head completion protein (GPL) LRR_7 PF13504.1 KNZ80487.1 - 1 9.8 13.5 2.7 8.5 0.1 5.5 5 0 0 5 5 5 0 Leucine rich repeat EPL1 PF10513.4 KNZ80488.1 - 5.5e-16 59.2 0.0 1.9e-15 57.4 0.0 2.0 1 0 0 1 1 1 1 Enhancer of polycomb-like SHIPPO-rpt PF07004.7 KNZ80489.1 - 0.012 16.4 0.3 5.2 8.1 0.1 2.8 2 0 0 2 2 2 0 Sperm-tail PG-rich repeat TMF_DNA_bd PF12329.3 KNZ80489.1 - 0.63 9.8 69.6 0.82 9.5 0.1 8.0 3 2 3 7 7 7 0 TATA element modulatory factor 1 DNA binding NIF PF03031.13 KNZ80490.1 - 8.6e-53 178.2 0.4 1.2e-52 177.7 0.3 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Borrelia_P83 PF05262.6 KNZ80491.1 - 3.6 5.7 16.5 5 5.2 11.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Laminin_II PF06009.7 KNZ80491.1 - 4.8 6.9 14.6 4.1 7.1 2.2 2.4 1 1 1 2 2 2 0 Laminin Domain II ATP-synt_B PF00430.13 KNZ80491.1 - 5.3 6.8 20.6 3 7.6 11.7 2.4 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) AAA_23 PF13476.1 KNZ80491.1 - 9.6 6.4 9.5 17 5.6 6.6 1.3 1 0 0 1 1 1 0 AAA domain TPP1 PF10341.4 KNZ80492.1 - 2.9e-06 27.1 0.0 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD bZIP_1 PF00170.16 KNZ80493.1 - 0.011 15.6 4.2 0.011 15.6 2.9 3.4 3 1 1 4 4 4 0 bZIP transcription factor DUF4164 PF13747.1 KNZ80493.1 - 0.15 12.1 5.4 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) GTPase_Cys_C PF12631.2 KNZ80493.1 - 0.27 11.6 3.3 15 6.0 2.3 2.3 1 1 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE NIF PF03031.13 KNZ80494.1 - 1.5e-52 177.4 0.1 2.3e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KNZ80494.1 - 0.014 15.6 0.2 0.19 11.9 0.0 2.1 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase PTPLA PF04387.9 KNZ80495.1 - 1.2e-41 141.8 6.1 2e-41 141.1 4.3 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Grp1_Fun34_YaaH PF01184.14 KNZ80497.1 - 3e-52 176.9 12.2 3.5e-52 176.7 8.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF939 PF06081.6 KNZ80497.1 - 0.014 15.2 2.7 0.017 14.9 1.8 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF939) His_Phos_2 PF00328.17 KNZ80498.1 - 1.6e-49 169.1 0.0 1.9e-49 168.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.20 KNZ80499.1 - 5.8e-65 219.0 0.0 8.4e-65 218.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ80499.1 - 5e-36 124.0 0.0 6.4e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ80499.1 - 1e-08 34.4 0.0 4.8e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KNZ80499.1 - 0.018 14.7 0.4 4.4 6.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KNZ80499.1 - 0.069 12.4 0.0 0.75 9.1 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 KNZ80499.1 - 0.088 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KNZ80499.1 - 0.09 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Med25_VWA PF11265.3 KNZ80500.1 - 0.071 12.1 0.0 0.25 10.3 0.0 1.8 1 1 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A DUF349 PF03993.7 KNZ80500.1 - 0.2 11.8 0.6 0.48 10.6 0.4 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) SH3_9 PF14604.1 KNZ80501.1 - 2.2e-11 43.1 0.1 3.8e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KNZ80501.1 - 2.9e-11 42.5 0.1 4.5e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KNZ80501.1 - 3.4e-10 39.2 0.0 5.4e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Adeno_E3_CR2 PF02439.10 KNZ80502.1 - 0.032 13.7 0.5 0.063 12.8 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.13 KNZ80502.1 - 0.1 12.3 0.5 0.17 11.6 0.3 1.5 1 1 0 1 1 1 0 Glycophorin A Glyco_hydro_16 PF00722.16 KNZ80503.1 - 8.5e-07 28.4 0.0 1.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CMD PF02627.15 KNZ80503.1 - 0.00033 20.4 0.0 0.0016 18.2 0.0 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Rad21_Rec8_N PF04825.8 KNZ80504.1 - 2.3e-29 101.5 0.4 3.9e-29 100.8 0.3 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KNZ80504.1 - 7.6e-14 50.6 0.0 1.3e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KNZ80504.1 - 0.031 13.8 0.0 0.81 9.2 0.0 2.3 2 0 0 2 2 2 0 ScpA/B protein PPR_2 PF13041.1 KNZ80505.1 - 5e-35 119.2 6.9 2.9e-05 23.9 0.0 9.4 4 3 6 10 10 10 9 PPR repeat family PPR_3 PF13812.1 KNZ80505.1 - 6.8e-29 97.7 8.2 0.0085 16.3 0.1 10.6 10 0 0 10 10 10 7 Pentatricopeptide repeat domain PPR PF01535.15 KNZ80505.1 - 2.9e-17 61.3 3.2 0.011 15.6 0.0 9.9 12 0 0 12 12 12 3 PPR repeat PPR_1 PF12854.2 KNZ80505.1 - 5.1e-11 41.8 5.0 0.0012 18.3 0.0 7.5 9 0 0 9 9 9 3 PPR repeat ECSIT PF06239.6 KNZ80505.1 - 2.6e-07 29.7 3.5 15 4.3 0.0 7.1 5 2 2 8 8 8 3 Evolutionarily conserved signalling intermediate in Toll pathway RabGAP-TBC PF00566.13 KNZ80505.1 - 0.2 11.1 1.5 1.8 7.9 0.0 2.6 3 0 0 3 3 3 0 Rab-GTPase-TBC domain DUF960 PF06124.6 KNZ80505.1 - 0.23 11.7 1.2 0.64 10.3 0.1 2.1 2 0 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) p450 PF00067.17 KNZ80506.1 - 9.5e-58 195.8 0.0 1.2e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FUSC_2 PF13515.1 KNZ80507.1 - 4.4e-17 62.1 10.8 4.4e-17 62.1 7.5 2.9 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 KNZ80507.1 - 9e-12 44.3 7.2 1.7e-09 36.8 2.2 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.7 KNZ80507.1 - 9.7e-10 37.5 12.1 9.7e-10 37.5 3.4 2.4 2 0 0 2 2 2 2 Fusaric acid resistance protein family DUF2421 PF10334.4 KNZ80507.1 - 6.3e-09 35.7 0.4 1.5e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) Pkinase PF00069.20 KNZ80508.1 - 3.8e-48 163.9 0.0 5.3e-39 133.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ80508.1 - 7e-19 67.8 0.0 1.8e-18 66.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ80508.1 - 7.6e-05 21.7 0.0 9.8e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ80508.1 - 0.00087 19.0 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KNZ80508.1 - 0.019 14.0 0.1 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HhH-GPD PF00730.20 KNZ80510.1 - 5e-14 52.5 0.0 9.9e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Inhibitor_I9 PF05922.11 KNZ80511.1 - 1.5e-08 35.0 0.2 2e-08 34.6 0.2 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 HisK_N PF09385.5 KNZ80511.1 - 0.033 13.8 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase N terminal SLAC1 PF03595.12 KNZ80513.1 - 1.2e-59 201.5 37.8 1.4e-59 201.4 26.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Viral_Beta_CD PF04530.7 KNZ80513.1 - 2.1 8.4 0.0 2.1 8.4 0.0 2.7 3 0 0 3 3 3 0 Viral Beta C/D like family CRA PF06589.6 KNZ80515.1 - 5.1 6.3 6.1 1.1 8.5 1.0 2.3 1 1 1 2 2 2 0 Circumsporozoite-related antigen (CRA) Lactamase_B PF00753.22 KNZ80516.1 - 6.3e-17 61.8 0.3 1.1e-16 61.1 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SLAC1 PF03595.12 KNZ80517.1 - 1.2e-61 208.2 49.6 1.5e-61 207.9 34.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Glyco_hydro_76 PF03663.9 KNZ80518.1 - 2.1e-40 139.2 18.7 2.4e-40 139.0 13.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Adenylate_cycl PF01295.13 KNZ80518.1 - 0.021 13.1 0.0 0.029 12.6 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I Sec7 PF01369.15 KNZ80519.1 - 1.2e-37 129.4 0.0 2.8e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KNZ80519.1 - 5e-29 100.8 0.0 1.5e-28 99.3 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain GATA PF00320.22 KNZ80519.1 - 1.7e-18 65.6 1.6 4.4e-18 64.3 1.1 1.8 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 KNZ80519.1 - 3.5e-13 48.8 1.9 7.7e-13 47.7 1.3 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Lzipper-MIP1 PF14389.1 KNZ80519.1 - 0.0025 17.8 1.3 0.0066 16.5 0.8 1.9 1 1 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 PH PF00169.24 KNZ80519.1 - 0.039 14.1 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 PH domain LINES_N PF14694.1 KNZ80519.1 - 0.48 9.6 0.0 0.9 8.7 0.0 1.3 1 0 0 1 1 1 0 Lines N-terminus Peptidase_A22B PF04258.8 KNZ80520.1 - 1.5e-65 221.5 3.2 1.9e-65 221.2 2.2 1.0 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 KNZ80520.1 - 1.9e-05 23.9 6.3 1.9e-05 23.9 4.4 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1119) UPF0233 PF06781.7 KNZ80520.1 - 0.029 13.9 0.2 0.087 12.4 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) G_glu_transpept PF01019.16 KNZ80521.1 - 2.4e-148 494.8 0.0 2.6e-148 494.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Sigma_1_2 PF03084.9 KNZ80524.1 - 0.017 13.7 0.0 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family Pkinase PF00069.20 KNZ80525.1 - 3.5e-69 232.8 0.0 4.4e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ80525.1 - 1.1e-37 129.5 0.0 1.9e-37 128.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.21 KNZ80525.1 - 1.2e-16 60.5 0.2 2.6e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 KNZ80525.1 - 1.9e-05 23.8 0.0 7.1e-05 21.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KNZ80525.1 - 0.001 18.1 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ80525.1 - 0.0045 16.7 0.0 0.018 14.7 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KNZ80525.1 - 0.039 13.2 0.0 0.077 12.3 0.0 1.5 1 1 0 1 1 1 0 RIO1 family DUF3460 PF11943.3 KNZ80525.1 - 0.08 13.0 0.1 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) RRM_1 PF00076.17 KNZ80526.1 - 8.4e-14 50.9 0.6 7.4e-06 25.5 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ80526.1 - 6.4e-11 42.0 0.1 0.00012 22.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ80526.1 - 1.4e-08 34.4 0.1 2.3e-06 27.3 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KNZ80526.1 - 0.011 15.4 0.0 3.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 KNZ80526.1 - 0.11 12.2 0.0 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Acyltransferase PF01553.16 KNZ80527.1 - 3.8e-17 61.9 0.0 6.9e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase SNARE_assoc PF09335.6 KNZ80527.1 - 0.0072 16.5 0.8 0.015 15.4 0.5 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein 60KD_IMP PF02096.15 KNZ80527.1 - 0.018 14.7 0.2 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein CobD_Cbib PF03186.8 KNZ80527.1 - 0.057 12.4 0.2 0.14 11.2 0.1 1.5 1 0 0 1 1 1 0 CobD/Cbib protein TarH PF02203.10 KNZ80528.1 - 0.003 17.3 7.8 0.3 10.9 0.3 2.5 1 1 1 2 2 2 2 Tar ligand binding domain homologue DED PF01335.16 KNZ80528.1 - 0.11 12.6 1.1 5 7.3 0.0 2.7 2 0 0 2 2 2 0 Death effector domain Cortex-I_coil PF09304.5 KNZ80528.1 - 1.2 9.2 8.4 4 7.5 4.0 2.5 2 1 1 3 3 3 0 Cortexillin I, coiled coil YbaB_DNA_bd PF02575.11 KNZ80528.1 - 1.8 8.5 5.8 1.8 8.4 0.0 3.3 3 1 1 4 4 4 0 YbaB/EbfC DNA-binding family SPC22 PF04573.7 KNZ80529.1 - 1e-41 142.0 0.3 1.2e-41 141.8 0.2 1.0 1 0 0 1 1 1 1 Signal peptidase subunit RE_R_Pab1 PF09522.5 KNZ80529.1 - 0.1 12.5 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 R.Pab1 restriction endonuclease DUF1236 PF06823.7 KNZ80530.1 - 0.17 11.6 0.8 7.3 6.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) Pkinase PF00069.20 KNZ80531.1 - 1.5e-67 227.5 0.0 1.9e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ80531.1 - 2.2e-39 135.1 0.0 3.1e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KNZ80531.1 - 6.6e-18 64.6 0.1 1.7e-17 63.2 0.1 1.8 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 KNZ80531.1 - 1.2e-06 27.7 0.0 2.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KNZ80531.1 - 3.4e-05 22.9 0.0 5.5e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ80531.1 - 0.005 16.6 0.0 0.1 12.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family S-methyl_trans PF02574.11 KNZ80532.1 - 1e-26 93.9 0.1 3.3e-11 43.0 0.0 3.1 2 1 1 3 3 3 3 Homocysteine S-methyltransferase Cytochrom_B561 PF03188.11 KNZ80533.1 - 1.6e-10 40.9 4.8 1.6e-10 40.9 3.3 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4386 PF14329.1 KNZ80533.1 - 0.0019 17.7 2.7 0.028 13.8 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4386) DOMON PF03351.12 KNZ80533.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 DOMON domain DUF1282 PF06930.7 KNZ80533.1 - 0.19 11.4 0.1 0.19 11.4 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1282) API5 PF05918.6 KNZ80534.1 - 7.2e-10 37.9 0.9 8.1e-10 37.8 0.6 1.1 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.1 KNZ80534.1 - 0.0014 18.8 0.0 0.01 16.1 0.0 2.4 2 1 0 2 2 2 1 HEAT repeats Cnd1 PF12717.2 KNZ80534.1 - 0.058 13.2 0.4 0.16 11.8 0.2 1.8 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Oxidored_q6 PF01058.17 KNZ80535.1 - 2.1e-22 79.1 0.1 3.2e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit SoxG PF04268.7 KNZ80535.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family Mnd1 PF03962.10 KNZ80537.1 - 5.4e-51 172.9 0.4 6.2e-51 172.7 0.3 1.0 1 0 0 1 1 1 1 Mnd1 family TrmB PF01978.14 KNZ80537.1 - 0.052 13.2 0.3 0.32 10.7 0.0 2.4 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB DUF4094 PF13334.1 KNZ80537.1 - 0.07 13.5 0.8 0.13 12.7 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) ABC_tran_2 PF12848.2 KNZ80537.1 - 1.1 9.1 8.6 0.36 10.7 3.8 1.8 2 0 0 2 2 2 0 ABC transporter COG2 PF06148.6 KNZ80537.1 - 1.7 8.4 6.0 2.8 7.8 4.1 1.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4404 PF14357.1 KNZ80537.1 - 1.8 9.0 6.2 8.5 6.8 3.6 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Zn_clus PF00172.13 KNZ80539.1 - 3e-08 33.4 11.9 5.3e-08 32.6 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KNZ80539.1 - 5.1e-07 28.8 0.0 9e-07 28.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain W2 PF02020.13 KNZ80540.1 - 2.5e-19 69.0 0.2 2.5e-19 69.0 0.1 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Casein PF00363.13 KNZ80540.1 - 0.25 12.0 2.5 0.25 11.9 0.4 2.0 2 0 0 2 2 2 0 Casein PP2C PF00481.16 KNZ80541.1 - 1.7e-55 188.1 0.1 1.8e-45 155.3 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C PF00481.16 KNZ80542.1 - 2.1e-67 227.1 0.2 6.5e-53 179.7 0.0 2.0 1 1 1 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 KNZ80542.1 - 1.2e-06 28.3 0.2 0.00061 19.5 0.1 2.9 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Choline_transpo PF04515.7 KNZ80543.1 - 5.6e-86 288.3 19.4 5.6e-86 288.3 13.4 2.8 2 1 1 3 3 3 2 Plasma-membrane choline transporter COX15-CtaA PF02628.10 KNZ80544.1 - 0.0093 14.8 0.3 0.017 13.9 0.0 1.5 2 0 0 2 2 2 1 Cytochrome oxidase assembly protein Claudin_2 PF13903.1 KNZ80544.1 - 0.06 13.0 4.2 0.062 12.9 2.1 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 KNZ80544.1 - 0.13 11.5 2.3 0.3 10.2 1.6 1.7 1 1 0 1 1 1 0 Clc-like Amastin PF07344.6 KNZ80544.1 - 0.15 11.7 7.8 0.022 14.3 1.9 2.0 2 1 0 2 2 2 0 Amastin surface glycoprotein TctB PF07331.6 KNZ80544.1 - 1.1 8.8 7.6 0.058 13.0 0.4 2.2 2 1 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family DUF4131 PF13567.1 KNZ80544.1 - 1.9 7.8 6.1 2.2 7.6 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) zf-RING_2 PF13639.1 KNZ80545.1 - 6e-11 41.9 1.4 2.1e-09 37.0 0.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KNZ80545.1 - 3.7e-07 30.0 3.4 8.8e-07 28.8 0.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KNZ80545.1 - 6.4e-07 29.3 0.6 2.9e-05 24.0 0.1 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KNZ80545.1 - 1.6e-06 27.7 1.1 1.1e-05 25.0 0.1 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KNZ80545.1 - 2.2e-05 24.0 3.5 8.6e-05 22.1 0.1 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNZ80545.1 - 0.00074 19.1 1.9 0.0016 18.1 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KNZ80545.1 - 0.0019 17.9 0.5 0.0042 16.8 0.1 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KNZ80545.1 - 0.0079 15.8 2.1 0.016 14.8 0.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger ELF PF03317.8 KNZ80545.1 - 0.088 12.0 3.7 0.13 11.5 2.6 1.3 1 0 0 1 1 1 0 ELF protein Prok-RING_4 PF14447.1 KNZ80545.1 - 0.096 12.2 0.2 0.31 10.6 0.1 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 KNZ80545.1 - 0.2 11.6 5.0 1.5 8.8 2.2 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 KNZ80545.1 - 0.22 11.4 2.8 0.2 11.5 0.2 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING GTP_EFTU PF00009.22 KNZ80547.1 - 7.1e-22 77.7 0.0 1.2e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KNZ80547.1 - 1.3e-13 50.9 0.1 2.8e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KNZ80547.1 - 9.2e-07 28.8 0.3 1.3e-05 25.1 0.1 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KNZ80547.1 - 0.02 14.5 0.0 0.071 12.7 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu domain 4 PduV-EutP PF10662.4 KNZ80547.1 - 0.03 13.7 0.6 1.7 8.1 0.1 2.9 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 KNZ80547.1 - 0.06 13.0 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KNZ80547.1 - 0.064 13.2 0.1 0.18 11.7 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase TerB-C PF15615.1 KNZ80547.1 - 0.32 11.2 1.5 0.6 10.3 1.0 1.3 1 0 0 1 1 1 0 TerB-C domain SKN1 PF03935.10 KNZ80548.1 - 1.6e-182 607.1 4.7 1.9e-182 606.9 3.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_18 PF00704.23 KNZ80549.1 - 6.8e-96 321.6 2.7 6.8e-96 321.6 1.9 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 KNZ80550.1 - 5.5e-10 38.7 10.5 1.1e-09 37.7 7.3 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain SNARE PF05739.14 KNZ80551.1 - 2.2e-14 52.8 0.2 5.3e-14 51.6 0.2 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 KNZ80551.1 - 3e-05 24.1 0.3 3e-05 24.1 0.2 3.1 1 1 1 2 2 2 1 Syntaxin POTRA_2 PF08479.6 KNZ80551.1 - 0.012 15.3 0.4 7.1 6.3 0.1 3.3 2 1 2 4 4 4 0 POTRA domain, ShlB-type DUF1359 PF07097.6 KNZ80551.1 - 0.015 15.3 0.7 0.068 13.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1359) Fe_hyd_lg_C PF02906.9 KNZ80553.1 - 1.7e-70 237.5 0.0 2.8e-70 236.8 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Ferrochelatase PF00762.14 KNZ80554.1 - 1.1e-93 313.6 0.0 1.3e-93 313.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase GHMP_kinases_N PF00288.21 KNZ80555.1 - 7.6e-11 41.9 3.0 1.6e-10 40.8 2.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KNZ80555.1 - 0.00035 20.7 0.0 0.00092 19.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Aa_trans PF01490.13 KNZ80556.1 - 8e-73 245.2 31.0 9.3e-73 245.0 21.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2574 PF10836.3 KNZ80556.1 - 0.02 14.5 1.8 4.3 7.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) Trp_Tyr_perm PF03222.8 KNZ80556.1 - 0.04 12.7 25.5 0.07 11.9 14.7 2.4 1 1 1 2 2 2 0 Tryptophan/tyrosine permease family MS_channel PF00924.13 KNZ80559.1 - 2.5e-23 82.5 0.9 2.5e-23 82.5 0.6 1.8 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KNZ80559.1 - 0.0035 16.5 0.4 0.0086 15.3 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 KNZ80559.1 - 0.0073 15.6 0.1 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KNZ80559.1 - 0.016 15.0 0.1 0.06 13.2 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.1 KNZ80559.1 - 0.017 14.7 0.1 0.038 13.5 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.1 KNZ80559.1 - 0.054 13.6 0.3 0.14 12.2 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain pair RNA_pol_A_bac PF01000.21 KNZ80560.1 - 1.9e-27 95.5 0.0 3.4e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KNZ80560.1 - 2.9e-16 58.3 0.0 4e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-CSL PF05207.8 KNZ80560.1 - 0.018 14.5 1.0 0.037 13.5 0.7 1.5 1 0 0 1 1 1 0 CSL zinc finger DUF22 PF01629.11 KNZ80560.1 - 0.033 13.6 0.1 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF22 Alpha-2-MRAP_N PF06400.6 KNZ80564.1 - 0.014 15.0 0.8 0.014 15.0 0.6 1.9 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, N-terminal domain Asp_protease PF09668.5 KNZ80565.1 - 0.021 14.3 0.1 0.072 12.6 0.0 1.8 1 1 1 2 2 2 0 Aspartyl protease UCH PF00443.24 KNZ80567.1 - 9.4e-29 100.3 0.0 1.4e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KNZ80567.1 - 1.2e-10 41.3 0.1 2.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Rsm22 PF09243.5 KNZ80568.1 - 8.5e-44 149.6 0.0 7.4e-41 139.9 0.0 3.1 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Ribosomal_L1 PF00687.16 KNZ80569.1 - 7.3e-17 61.4 0.0 2.5e-16 59.6 0.0 1.9 1 1 1 2 2 2 1 Ribosomal protein L1p/L10e family MRP-L28 PF09812.4 KNZ80570.1 - 1.9e-11 44.0 4.5 3.5e-10 39.9 1.4 2.3 1 1 0 2 2 2 2 Mitochondrial ribosomal protein L28 Peptidase_M85 PF13678.1 KNZ80570.1 - 0.11 11.8 0.2 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 NFkB-p65-degrading zinc protease PCI PF01399.22 KNZ80571.1 - 3.2e-18 65.9 0.3 8.6e-18 64.5 0.2 1.8 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 KNZ80571.1 - 9.1e-10 38.4 0.2 2e-09 37.3 0.2 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 PIP5K PF01504.13 KNZ80572.1 - 3.8e-66 222.7 0.1 6.7e-66 221.9 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KNZ80572.1 - 1.4e-24 86.5 0.0 2.1e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KNZ80572.1 - 2.8e-17 62.3 12.4 2.8e-17 62.3 8.6 2.1 2 0 0 2 2 2 1 FYVE zinc finger IBR PF01485.16 KNZ80572.1 - 4.6 7.1 12.2 1.2 9.0 5.6 2.1 2 0 0 2 2 2 0 IBR domain Bromodomain PF00439.20 KNZ80573.1 - 1e-51 172.8 0.0 1.2e-18 66.7 0.1 3.5 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.15 KNZ80573.1 - 3.4e-13 49.4 0.0 1.5e-11 44.0 0.0 2.5 2 1 0 2 2 2 1 Peptidase family M1 HEAT_2 PF13646.1 KNZ80573.1 - 0.032 14.4 0.0 7.2 6.9 0.0 3.5 3 0 0 3 3 3 0 HEAT repeats Peptidase_MA_2 PF13485.1 KNZ80573.1 - 0.046 13.7 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Peptidase MA superfamily LTV PF04180.9 KNZ80574.1 - 2.1e-66 225.1 21.6 1.5e-48 166.3 1.5 3.1 2 1 1 3 3 3 3 Low temperature viability protein Het-C PF07217.6 KNZ80575.1 - 3.5e-189 629.9 0.0 1.6e-188 627.7 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Med11 PF10280.4 KNZ80576.1 - 1.5e-06 28.2 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Mediator complex protein TBCA PF02970.11 KNZ80577.1 - 6.2e-16 58.2 4.5 6.5e-16 58.1 2.4 1.5 1 1 0 1 1 1 1 Tubulin binding cofactor A AdoMet_Synthase PF01941.14 KNZ80577.1 - 0.028 12.9 0.1 0.033 12.6 0.0 1.0 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) DUF2749 PF10907.3 KNZ80577.1 - 0.12 12.2 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) HLH PF00010.21 KNZ80578.1 - 9.3e-10 38.0 1.7 9.3e-10 38.0 1.2 2.0 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF641 PF04859.7 KNZ80578.1 - 0.0033 17.2 1.7 0.0049 16.6 1.2 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) NIT PF08376.5 KNZ80578.1 - 0.015 14.8 2.7 0.022 14.3 1.9 1.2 1 0 0 1 1 1 0 Nitrate and nitrite sensing FliJ PF02050.11 KNZ80578.1 - 0.15 12.1 4.5 0.21 11.6 3.1 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF342 PF03961.8 KNZ80578.1 - 0.62 8.4 1.6 0.79 8.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4164 PF13747.1 KNZ80578.1 - 0.72 10.0 5.6 0.67 10.1 2.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) HLH PF00010.21 KNZ80579.1 - 1.7e-11 43.6 2.9 1.1e-09 37.7 1.2 2.6 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain DUF342 PF03961.8 KNZ80579.1 - 0.032 12.6 1.2 0.044 12.2 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Chitin_synth_1 PF01644.12 KNZ80581.1 - 4.1e-77 257.5 0.1 6.7e-77 256.8 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KNZ80581.1 - 3.7e-25 87.4 0.0 1e-24 86.0 0.0 1.7 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KNZ80581.1 - 1.9e-21 76.0 0.3 4.1e-16 58.4 0.0 2.6 2 1 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 KNZ80581.1 - 1.2e-06 28.5 0.0 8.8e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KNZ80581.1 - 6.7e-06 25.9 0.2 6.7e-06 25.9 0.2 2.4 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Pkinase PF00069.20 KNZ80582.1 - 6.5e-38 130.3 0.0 8.1e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ80582.1 - 2.2e-13 49.8 0.0 2.9e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ80582.1 - 4.5e-05 23.2 0.1 0.0026 17.5 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KNZ80582.1 - 0.014 14.1 0.1 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Adaptin_N PF01602.15 KNZ80583.1 - 7.7e-112 374.2 0.1 4e-111 371.9 0.1 1.9 1 1 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KNZ80583.1 - 1.1e-51 174.5 2.8 3.3e-51 173.0 1.9 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KNZ80583.1 - 8.5e-15 54.8 10.7 0.00082 19.6 0.1 6.7 3 2 3 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 KNZ80583.1 - 9e-05 22.8 6.2 0.14 12.6 0.0 4.2 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 KNZ80583.1 - 0.0085 16.1 13.2 3.6 7.9 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat HEAT_PBS PF03130.11 KNZ80583.1 - 0.18 12.3 4.1 14 6.5 0.0 5.6 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat PIF1 PF05970.9 KNZ80584.1 - 4.7e-31 108.0 0.2 1.1e-30 106.8 0.1 1.6 1 1 0 1 1 1 1 PIF1-like helicase Fumble PF03630.9 KNZ80585.1 - 3e-117 391.2 0.0 9.1e-117 389.7 0.0 1.6 1 1 0 1 1 1 1 Fumble Homeobox PF00046.24 KNZ80586.1 - 7.3e-47 156.8 9.4 1.1e-17 63.3 0.3 3.5 3 0 0 3 3 3 3 Homeobox domain Homeobox_KN PF05920.6 KNZ80586.1 - 2.3e-15 56.0 1.6 0.00033 20.3 0.2 3.6 3 0 0 3 3 3 3 Homeobox KN domain HTH_3 PF01381.17 KNZ80586.1 - 0.00014 21.6 0.3 0.53 10.1 0.0 3.4 3 0 0 3 3 3 2 Helix-turn-helix HTH_26 PF13443.1 KNZ80586.1 - 0.057 13.6 1.7 15 5.8 0.0 3.9 4 0 0 4 4 4 0 Cro/C1-type HTH DNA-binding domain HTH_OrfB_IS605 PF12323.3 KNZ80586.1 - 1 8.7 3.8 4.4 6.7 0.0 2.7 2 1 1 3 3 3 0 Helix-turn-helix domain polyprenyl_synt PF00348.12 KNZ80587.1 - 3.8e-13 48.8 0.0 7.5e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 KNZ80587.1 - 0.065 12.6 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 RRM_1 PF00076.17 KNZ80588.1 - 1.6e-10 40.4 0.1 3.2e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ80588.1 - 2.3e-08 33.7 0.0 1.4e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ80588.1 - 2.5e-05 24.1 0.0 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KNZ80588.1 - 0.079 12.7 0.0 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ras PF00071.17 KNZ80589.1 - 1.2e-59 200.3 0.1 1.3e-59 200.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ80589.1 - 9.4e-20 71.2 0.0 1.3e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ80589.1 - 1.5e-14 53.6 0.1 1.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KNZ80589.1 - 1.7e-06 27.6 0.0 3.3e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KNZ80589.1 - 5.2e-06 26.4 0.0 9.8e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KNZ80589.1 - 1e-05 24.8 0.0 1.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 KNZ80589.1 - 0.03 14.2 0.4 0.12 12.3 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KNZ80589.1 - 0.035 14.2 0.1 0.33 11.0 0.0 2.5 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KNZ80589.1 - 0.04 13.1 0.2 0.14 11.3 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function, DUF258 Septin PF00735.13 KNZ80589.1 - 0.058 12.3 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Septin SRPRB PF09439.5 KNZ80589.1 - 0.081 12.1 0.1 0.23 10.6 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KNZ80589.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 KNZ80589.1 - 0.15 10.6 0.3 5.6 5.5 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit RasGEF PF00617.14 KNZ80590.1 - 9.8e-40 136.2 0.0 1.8e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KNZ80590.1 - 7.3e-15 54.9 0.5 1.8e-14 53.6 0.4 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KNZ80590.1 - 8.2e-11 41.1 0.8 1.8e-10 40.0 0.6 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KNZ80590.1 - 2.2e-09 36.7 1.5 3e-09 36.2 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KNZ80590.1 - 2.2e-07 30.2 0.0 6e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Ribosomal_L30 PF00327.15 KNZ80591.1 - 4.7e-11 42.0 0.4 6.7e-11 41.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e GWT1 PF06423.7 KNZ80592.1 - 8.8e-31 106.8 1.0 5e-30 104.3 0.0 2.7 2 1 0 2 2 2 1 GWT1 F-box-like PF12937.2 KNZ80593.1 - 5.4e-05 22.8 1.1 5.4e-05 22.8 0.8 2.3 2 0 0 2 2 2 1 F-box-like PSS PF03034.10 KNZ80593.1 - 0.036 13.4 0.7 0.07 12.5 0.5 1.4 1 0 0 1 1 1 0 Phosphatidyl serine synthase Ist1 PF03398.9 KNZ80594.1 - 3.7e-61 205.3 1.7 4.6e-61 205.0 1.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway MLANA PF14991.1 KNZ80595.1 - 0.072 13.1 0.0 0.3 11.0 0.0 2.1 1 0 0 1 1 1 0 Protein melan-A Adeno_E3_CR2 PF02439.10 KNZ80595.1 - 0.2 11.2 0.1 0.41 10.2 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DSHCT PF08148.7 KNZ80596.1 - 3.4e-55 186.0 0.4 6.6e-55 185.1 0.3 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KNZ80596.1 - 7.8e-22 77.5 0.6 2.5e-21 75.9 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ80596.1 - 1.5e-05 24.7 0.0 3.7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ80596.1 - 0.027 14.2 0.1 0.17 11.7 0.1 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DnaB_2 PF07261.6 KNZ80597.1 - 0.013 15.0 0.1 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Replication initiation and membrane attachment DUF2414 PF10309.4 KNZ80598.1 - 5.2e-07 29.2 0.0 8.4e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 KNZ80598.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 RNA binding domain GTP_EFTU PF00009.22 KNZ80599.1 - 1.9e-62 210.0 0.2 2.9e-62 209.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KNZ80599.1 - 1.5e-13 50.3 0.0 3.6e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KNZ80599.1 - 4.6e-12 45.8 0.0 2.7e-11 43.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KNZ80599.1 - 4.8e-06 26.5 0.1 8.9e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pox_RNA_pol PF03293.9 KNZ80599.1 - 0.0047 16.4 0.2 4 6.9 0.0 2.8 3 0 0 3 3 3 2 Poxvirus DNA-directed RNA polymerase, 18 kD subunit PduV-EutP PF10662.4 KNZ80599.1 - 0.026 14.0 0.3 0.13 11.7 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Acetyltransf_3 PF13302.1 KNZ80600.1 - 8.9e-18 64.8 0.0 1.5e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KNZ80600.1 - 5.4e-06 26.3 0.0 8.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KNZ80600.1 - 9.3e-06 25.6 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KNZ80600.1 - 0.0053 16.6 0.0 0.028 14.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KNZ80600.1 - 0.0072 16.4 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SH3_1 PF00018.23 KNZ80601.1 - 3.2e-12 45.6 0.1 5.7e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KNZ80601.1 - 2.4e-09 36.6 0.0 4.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KNZ80601.1 - 1.4e-07 30.9 0.0 2.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain zf-C3HC4_2 PF13923.1 KNZ80602.1 - 8.2e-11 41.7 11.1 1.4e-10 40.9 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ80602.1 - 1.2e-09 37.6 9.4 2e-09 36.9 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ80602.1 - 5e-09 35.8 9.0 9.2e-09 35.0 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KNZ80602.1 - 2.7e-08 33.3 6.6 4.2e-08 32.7 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KNZ80602.1 - 6.9e-06 25.8 11.1 1.4e-05 24.8 7.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KNZ80602.1 - 8.5e-06 25.4 10.4 1.8e-05 24.3 7.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KNZ80602.1 - 0.00029 20.4 4.0 0.00029 20.4 2.8 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KNZ80602.1 - 0.0017 18.4 6.8 0.0054 16.8 4.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 KNZ80602.1 - 0.0056 16.1 8.3 0.011 15.2 5.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 KNZ80602.1 - 0.039 13.7 4.9 0.23 11.2 3.4 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KNZ80602.1 - 0.053 13.3 3.2 0.1 12.4 2.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 KNZ80602.1 - 0.093 12.2 10.3 0.12 11.9 6.4 1.7 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger NpwBP PF12622.2 KNZ80603.1 - 2.7e-18 66.1 2.8 2.7e-18 66.1 1.9 6.0 4 1 0 4 4 4 1 mRNA biogenesis factor Wbp11 PF09429.5 KNZ80603.1 - 7.2e-18 64.3 17.8 1.9e-17 63.0 12.3 1.7 1 0 0 1 1 1 1 WW domain binding protein 11 Colicin_Pyocin PF01320.13 KNZ80603.1 - 0.031 14.1 0.1 0.069 13.0 0.1 1.6 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein APG6 PF04111.7 KNZ80603.1 - 7.6 5.4 10.6 12 4.7 6.5 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 FAD_binding_3 PF01494.14 KNZ80605.1 - 3.8e-14 52.5 0.0 1e-10 41.2 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 KNZ80605.1 - 0.004 16.0 0.1 0.04 12.7 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase HIT PF01230.18 KNZ80606.1 - 1.3e-25 89.7 0.0 1.8e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KNZ80606.1 - 5.8e-07 29.7 0.0 8.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KNZ80606.1 - 0.027 14.1 0.0 0.041 13.5 0.0 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 F-box-like PF12937.2 KNZ80607.1 - 1.1e-05 25.0 0.3 5e-05 22.9 0.2 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KNZ80607.1 - 0.48 10.1 4.7 20 4.9 0.0 4.6 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) Metallophos PF00149.23 KNZ80608.1 - 6e-10 38.8 1.0 1.3e-09 37.7 0.7 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KNZ80608.1 - 0.00052 19.8 0.0 0.0026 17.6 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF221 PF02714.10 KNZ80609.1 - 1.7e-15 56.7 15.1 2.8e-15 55.9 10.5 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KNZ80609.1 - 4.9e-05 22.9 0.2 4.9e-05 22.9 0.1 2.8 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KNZ80609.1 - 0.00018 21.3 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KNZ80609.1 - 0.064 13.7 0.0 0.19 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) Sec1 PF00995.18 KNZ80610.1 - 2.5e-142 475.4 0.0 2.8e-142 475.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family YcaO PF02624.11 KNZ80610.1 - 0.11 11.9 1.7 2.2 7.6 0.1 2.5 2 1 0 2 2 2 0 YcaO-like family Bax1-I PF01027.15 KNZ80611.1 - 5e-34 117.7 9.1 5e-34 117.7 6.3 1.5 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 DUF2975 PF11188.3 KNZ80611.1 - 0.043 13.5 0.6 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DUF2076 PF09849.4 KNZ80611.1 - 0.077 13.0 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) WD40 PF00400.27 KNZ80612.1 - 9.8e-47 155.2 22.0 8.5e-09 34.9 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat LisH PF08513.6 KNZ80612.1 - 3.5e-05 23.4 0.0 6.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 LisH SH3_6 PF12913.2 KNZ80612.1 - 0.019 14.1 0.1 4.2 6.6 0.0 2.6 2 0 0 2 2 2 0 SH3 domain of the SH3b1 type Nbas_N PF15492.1 KNZ80612.1 - 0.037 13.1 0.1 0.99 8.4 0.0 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.27 KNZ80613.1 - 1.8e-24 84.6 12.4 1.1e-08 34.5 1.3 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat RicinB_lectin_2 PF14200.1 KNZ80614.1 - 5e-05 23.6 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KNZ80614.1 - 0.0022 18.0 0.0 0.7 9.9 0.0 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Arginase PF00491.16 KNZ80615.1 - 1.1e-76 257.7 0.0 2e-76 256.9 0.0 1.3 1 1 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KNZ80615.1 - 0.043 14.0 0.0 0.066 13.4 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Abhydrolase_1 PF00561.15 KNZ80616.1 - 1.2e-10 41.2 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KNZ80616.1 - 1.7e-06 28.0 0.0 5.9e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ80616.1 - 4.1e-06 26.5 0.0 1.6e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family GCFC PF07842.7 KNZ80616.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein SUR7 PF06687.7 KNZ80617.1 - 1e-20 74.2 18.0 1.4e-20 73.8 12.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Sin3_corepress PF08295.7 KNZ80618.1 - 8.1e-36 121.8 0.1 1.8e-35 120.7 0.1 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 KNZ80618.1 - 4.4e-34 115.8 8.2 2.4e-12 46.2 1.1 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat TMEM154 PF15102.1 KNZ80619.1 - 0.063 12.9 2.2 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family MLTD_N PF06474.7 KNZ80619.1 - 0.1 12.8 3.5 0.36 11.0 0.4 2.8 2 0 0 2 2 2 0 MltD lipid attachment motif Yip1 PF04893.12 KNZ80619.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 2 0 0 2 2 2 0 Yip1 domain HEAT_2 PF13646.1 KNZ80620.1 - 7.7e-06 26.0 0.2 0.12 12.6 0.1 3.3 3 0 0 3 3 3 2 HEAT repeats Arm PF00514.18 KNZ80620.1 - 0.0031 17.2 0.0 0.0031 17.2 0.0 3.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 KNZ80620.1 - 0.0095 15.6 2.6 0.015 14.9 0.1 2.4 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis NAD_binding_2 PF03446.10 KNZ80621.1 - 1.1e-23 83.8 0.0 2.3e-23 82.8 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KNZ80621.1 - 1.6e-08 34.6 0.1 4.2e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 KNZ80621.1 - 8.9e-08 32.3 0.0 3e-07 30.6 0.0 1.8 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KNZ80621.1 - 3.3e-07 30.6 0.1 1.2e-06 28.8 0.0 2.1 2 1 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.11 KNZ80621.1 - 7.3e-05 23.1 0.0 0.00016 22.0 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 KNZ80621.1 - 9.6e-05 21.2 0.0 0.0011 17.8 0.0 2.3 2 1 1 3 3 3 1 Ornithine cyclodeaminase/mu-crystallin family Semialdhyde_dh PF01118.19 KNZ80621.1 - 0.00018 21.8 0.1 0.64 10.3 0.0 2.5 1 1 1 2 2 2 2 Semialdehyde dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KNZ80621.1 - 0.0029 17.3 0.3 0.01 15.5 0.2 2.0 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FR47 PF08445.5 KNZ80621.1 - 0.0042 16.7 0.0 0.012 15.3 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein 2-Hacid_dh_C PF02826.14 KNZ80621.1 - 0.0083 15.2 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KNZ80621.1 - 0.0091 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase ApbA PF02558.11 KNZ80621.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF4164 PF13747.1 KNZ80621.1 - 0.051 13.7 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) GFO_IDH_MocA PF01408.17 KNZ80621.1 - 0.055 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 KNZ80621.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3HCDH_N PF02737.13 KNZ80621.1 - 0.1 12.2 2.1 1.4 8.5 1.4 2.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 KNZ80622.1 - 5e-40 137.2 0.0 7.5e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ80622.1 - 7.9e-28 97.2 0.0 1.1e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ80622.1 - 0.24 10.3 0.0 0.39 9.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KNZ80623.1 - 3.6e-13 49.8 0.0 8.2e-13 48.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ80623.1 - 2.6e-06 27.1 0.0 4.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KNZ80623.1 - 0.015 14.6 0.0 0.085 12.1 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 KNZ80623.1 - 0.017 14.2 0.0 4.4 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Dioxygenase_C PF00775.16 KNZ80624.1 - 3.2e-05 23.2 0.1 8.8e-05 21.8 0.1 1.8 1 1 1 2 2 2 1 Dioxygenase Isochorismatase PF00857.15 KNZ80626.1 - 6.1e-28 97.9 0.0 8.4e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family HA2 PF04408.18 KNZ80627.1 - 1.4e-24 86.0 0.0 4.2e-24 84.5 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KNZ80627.1 - 2.1e-14 53.3 0.0 7.6e-14 51.5 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KNZ80627.1 - 6.4e-07 29.0 1.3 0.014 14.9 0.1 2.6 1 1 1 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.1 KNZ80627.1 - 0.00019 21.5 0.1 0.00056 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KNZ80627.1 - 0.00085 18.2 0.0 0.0016 17.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 KNZ80627.1 - 0.0016 18.1 0.1 0.0044 16.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 KNZ80627.1 - 0.0042 16.2 0.4 0.093 11.8 0.0 2.7 2 1 1 3 3 3 1 Zeta toxin KaiC PF06745.8 KNZ80627.1 - 0.013 14.5 0.0 0.034 13.2 0.0 1.6 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 KNZ80627.1 - 0.059 13.6 0.1 0.19 12.0 0.0 1.9 2 0 0 2 2 1 0 ABC transporter NACHT PF05729.7 KNZ80627.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Helicase_C PF00271.26 KNZ80627.1 - 0.075 12.9 0.2 0.21 11.4 0.1 1.8 2 0 0 2 2 1 0 Helicase conserved C-terminal domain FtsK_SpoIIIE PF01580.13 KNZ80627.1 - 0.085 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 KNZ80627.1 - 0.09 11.6 0.2 0.5 9.1 0.0 2.2 3 0 0 3 3 3 0 NB-ARC domain AAA_30 PF13604.1 KNZ80627.1 - 0.094 12.2 0.1 0.24 10.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KNZ80627.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 KNZ80627.1 - 0.14 11.9 0.0 6.1 6.6 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit UPF0079 PF02367.12 KNZ80627.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 OB_NTP_bind PF07717.11 KNZ80628.1 - 2.3e-30 104.7 0.0 5.2e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KNZ80628.1 - 1.3e-29 102.1 0.9 2.5e-29 101.2 0.1 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KNZ80628.1 - 1.9e-12 46.8 0.0 4.8e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KNZ80628.1 - 5.4e-08 32.8 0.1 1.5e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 S1 RNA binding domain T2SE PF00437.15 KNZ80628.1 - 0.00019 20.4 0.0 0.00036 19.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.24 KNZ80628.1 - 0.0042 16.5 1.1 1.1 8.6 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase AAA_19 PF13245.1 KNZ80628.1 - 0.0054 16.4 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KNZ80628.1 - 0.014 15.5 1.2 0.058 13.5 0.2 2.4 2 1 0 2 2 2 0 AAA domain RS4NT PF08071.7 KNZ80628.1 - 0.016 15.0 0.1 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 RS4NT (NUC023) domain AAA_25 PF13481.1 KNZ80628.1 - 0.034 13.5 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KNZ80628.1 - 0.05 13.1 0.1 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KNZ80628.1 - 0.11 12.8 0.1 2 8.7 0.0 2.7 2 0 0 2 2 2 0 ABC transporter NTF2 PF02136.15 KNZ80629.1 - 0.0029 17.9 0.0 0.046 14.0 0.0 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 KNZ80629.1 - 0.0064 16.2 0.0 0.0072 16.1 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Exo_endo_phos PF03372.18 KNZ80630.1 - 2.1e-22 80.3 0.0 2.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Abhydrolase_3 PF07859.8 KNZ80631.1 - 2e-47 161.5 0.0 2.8e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KNZ80631.1 - 3.9e-14 52.0 0.0 9.7e-14 50.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KNZ80631.1 - 0.00022 21.0 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KNZ80631.1 - 0.028 13.1 0.0 0.45 9.1 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_M24 PF00557.19 KNZ80632.1 - 4e-43 147.4 0.1 4.9e-43 147.1 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 RibD_C PF01872.12 KNZ80633.1 - 5.5e-30 104.4 0.0 7.5e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain ZZ PF00569.12 KNZ80634.1 - 2.5e-19 68.5 41.9 4.6e-09 35.6 3.4 4.5 4 0 0 4 4 4 3 Zinc finger, ZZ type Aminotran_4 PF01063.14 KNZ80636.1 - 2.4e-22 79.5 0.0 3.1e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV WD40 PF00400.27 KNZ80637.1 - 5.4e-77 251.1 29.5 3.8e-09 36.0 0.1 11.6 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 KNZ80637.1 - 4.1e-43 146.3 0.0 6.4e-43 145.7 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.6 KNZ80637.1 - 1.1e-06 27.7 3.1 1.4 7.6 0.0 5.0 4 2 2 6 6 6 4 Nup133 N terminal like MMS1_N PF10433.4 KNZ80637.1 - 0.0031 15.7 0.0 0.17 9.9 0.0 2.5 2 1 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Arena_nucleocap PF00843.12 KNZ80637.1 - 0.064 11.1 0.3 6.7 4.4 0.0 3.0 3 0 0 3 3 3 0 Arenavirus nucleocapsid protein Vps16_C PF04840.7 KNZ80637.1 - 0.094 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Vps16, C-terminal region Fork_head PF00250.13 KNZ80638.1 - 1.3e-19 69.9 0.0 2.9e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Fork head domain Macoilin PF09726.4 KNZ80638.1 - 0.00012 20.5 2.8 0.00016 20.1 1.9 1.2 1 0 0 1 1 1 1 Transmembrane protein DUF648 PF04890.8 KNZ80638.1 - 0.0014 17.9 0.1 0.002 17.3 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF648) AT_hook PF02178.14 KNZ80638.1 - 0.018 14.6 2.6 0.018 14.6 1.8 3.1 3 0 0 3 3 3 0 AT hook motif Fungal_trans PF04082.13 KNZ80639.1 - 5.8e-17 61.4 0.1 6.5e-13 48.1 0.1 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ80639.1 - 8.6e-06 25.5 7.5 1.4e-05 24.9 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NIPSNAP PF07978.8 KNZ80640.1 - 1e-32 112.1 0.7 6.3e-27 93.5 0.2 2.1 2 0 0 2 2 2 2 NIPSNAP Proteasome PF00227.21 KNZ80641.1 - 1.6e-37 128.6 0.0 1.8e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit MoaC PF01967.16 KNZ80642.1 - 7.3e-42 142.2 0.4 1.2e-37 128.6 0.3 2.3 2 0 0 2 2 2 2 MoaC family Mob_synth_C PF06463.8 KNZ80642.1 - 8.4e-36 122.4 0.0 1.4e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KNZ80642.1 - 2e-24 86.6 0.0 4.7e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KNZ80642.1 - 1.7e-06 28.2 0.0 3.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KNZ80642.1 - 1e-05 25.5 0.0 3.8e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Apis_Csd PF11671.3 KNZ80643.1 - 0.13 12.0 1.5 0.3 10.8 1.0 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein CPW_WPC PF09717.5 KNZ80643.1 - 3.4 8.3 5.9 2.2 8.9 2.1 2.0 2 0 0 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Mito_carr PF00153.22 KNZ80644.1 - 9e-71 233.6 1.1 2.1e-24 85.0 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Met_10 PF02475.11 KNZ80644.1 - 3.1e-63 213.0 0.0 6.5e-63 211.9 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein EF-hand_7 PF13499.1 KNZ80644.1 - 3.7e-17 62.2 1.2 1.5e-05 25.0 0.1 4.7 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 KNZ80644.1 - 2.9e-16 57.4 5.2 6.8e-07 28.1 0.2 5.8 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.1 KNZ80644.1 - 2e-15 55.2 4.6 1.9e-05 24.1 0.0 5.9 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.1 KNZ80644.1 - 1.1e-11 44.1 3.4 0.00023 20.7 0.3 5.3 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 KNZ80644.1 - 3.2e-07 29.3 6.1 0.00029 20.0 0.1 3.9 3 0 0 3 3 3 2 EF hand Methyltransf_26 PF13659.1 KNZ80644.1 - 1.5e-05 25.0 0.0 0.00029 20.8 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain TatD_DNase PF01026.16 KNZ80645.1 - 1.9e-16 60.0 0.0 2.2e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase V-SNARE_C PF12352.3 KNZ80646.1 - 3.4e-15 55.8 0.5 3.4e-15 55.8 0.3 3.2 3 1 1 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus IncA PF04156.9 KNZ80646.1 - 0.0097 15.5 5.2 0.0097 15.5 3.6 1.9 3 0 0 3 3 2 1 IncA protein Ax_dynein_light PF10211.4 KNZ80646.1 - 0.015 15.1 0.8 0.027 14.2 0.5 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain TMPIT PF07851.8 KNZ80646.1 - 0.046 12.8 0.4 0.077 12.0 0.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein HlyD PF00529.15 KNZ80646.1 - 0.074 12.3 5.6 0.098 11.9 3.9 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Sec20 PF03908.8 KNZ80646.1 - 0.088 12.5 0.2 1 9.1 0.0 2.4 2 1 1 3 3 3 0 Sec20 DUF2730 PF10805.3 KNZ80646.1 - 0.13 11.9 0.8 2.7 7.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) AbiH PF14253.1 KNZ80646.1 - 0.19 11.3 0.5 0.32 10.5 0.2 1.3 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH Tropomyosin_1 PF12718.2 KNZ80646.1 - 0.46 10.3 6.9 0.29 10.9 2.8 2.1 1 1 1 2 2 2 0 Tropomyosin like FlgN PF05130.7 KNZ80646.1 - 0.53 10.5 8.6 0.2 11.9 3.1 2.2 1 1 1 2 2 2 0 FlgN protein TBPIP PF07106.8 KNZ80646.1 - 0.63 9.5 4.8 2.3 7.7 1.1 2.3 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIVA PF05103.8 KNZ80646.1 - 1.2 9.2 7.7 2.1 8.4 3.2 2.5 2 1 1 3 3 3 0 DivIVA protein Syntaxin-6_N PF09177.6 KNZ80646.1 - 1.3 9.4 5.2 7.9 6.9 3.0 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal HAUS-augmin3 PF14932.1 KNZ80646.1 - 2.6 7.1 7.0 2.5 7.2 4.0 1.5 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 CorA PF01544.13 KNZ80646.1 - 3.5 6.5 7.6 1.1 8.2 0.3 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein PilJ PF13675.1 KNZ80646.1 - 5.2 7.4 8.4 20 5.5 1.7 3.1 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term SnoaL_2 PF12680.2 KNZ80647.1 - 0.00042 20.6 0.0 0.001 19.4 0.0 1.7 2 0 0 2 2 2 1 SnoaL-like domain DUF2358 PF10184.4 KNZ80647.1 - 0.0016 18.3 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) Lgl_C PF08596.5 KNZ80648.1 - 8.2e-38 129.8 0.0 1.1e-36 126.2 0.0 2.4 2 1 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KNZ80648.1 - 0.0054 16.5 0.0 0.033 14.0 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Synaptobrevin PF00957.16 KNZ80648.1 - 0.034 13.7 0.4 0.064 12.8 0.3 1.3 1 0 0 1 1 1 0 Synaptobrevin Myosin_tail_1 PF01576.14 KNZ80649.1 - 1.1e-06 26.7 37.5 1.1e-06 26.7 26.0 7.5 3 1 2 6 6 6 3 Myosin tail DUF89 PF01937.14 KNZ80650.1 - 9.6e-104 346.9 0.0 1.1e-103 346.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Asp PF00026.18 KNZ80651.1 - 7.5e-44 150.2 6.2 2.2e-43 148.7 4.3 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNZ80651.1 - 1.3e-06 28.4 2.6 1.2e-05 25.3 0.9 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KNZ80651.1 - 0.0021 18.5 6.3 0.019 15.4 0.8 3.0 2 1 0 2 2 2 2 Aspartyl protease ABC_tran PF00005.22 KNZ80652.1 - 5e-49 166.1 0.2 6.5e-28 97.7 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KNZ80652.1 - 9.1e-40 136.8 21.7 5.1e-23 81.8 5.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KNZ80652.1 - 1.1e-10 41.1 3.3 2e-05 23.9 0.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KNZ80652.1 - 5.4e-09 35.7 0.1 0.00035 20.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KNZ80652.1 - 6e-07 28.9 2.7 0.0012 18.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KNZ80652.1 - 3.5e-06 26.1 0.3 0.026 13.4 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 KNZ80652.1 - 8e-06 25.4 4.9 0.017 14.5 0.1 3.1 2 1 0 2 2 2 2 AAA-like domain AAA_16 PF13191.1 KNZ80652.1 - 1.8e-05 24.8 0.9 0.09 12.7 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KNZ80652.1 - 2.4e-05 24.7 2.1 0.00093 19.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KNZ80652.1 - 8.2e-05 21.7 0.2 0.09 11.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin MobB PF03205.9 KNZ80652.1 - 0.00024 20.8 0.2 0.11 12.1 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KNZ80652.1 - 0.00026 21.7 1.1 0.054 14.3 0.0 3.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KNZ80652.1 - 0.00043 19.8 0.2 0.89 8.9 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_18 PF13238.1 KNZ80652.1 - 0.00094 19.4 0.3 0.11 12.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KNZ80652.1 - 0.0011 18.9 8.0 2 8.3 0.4 4.8 3 2 0 4 4 3 1 AAA domain DUF87 PF01935.12 KNZ80652.1 - 0.0014 18.4 5.0 0.0087 15.8 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 KNZ80652.1 - 0.0034 17.5 5.7 0.64 10.1 0.8 3.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KNZ80652.1 - 0.0044 16.9 0.3 6 6.7 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.1 KNZ80652.1 - 0.0064 16.0 0.0 0.38 10.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KNZ80652.1 - 0.012 15.4 0.0 6.5 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KNZ80652.1 - 0.02 14.8 0.1 12 5.8 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 KNZ80652.1 - 0.024 14.5 0.4 0.77 9.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 KNZ80652.1 - 0.028 14.1 0.1 1.7 8.3 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 KNZ80652.1 - 0.03 14.4 0.2 8.6 6.5 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Miro PF08477.8 KNZ80652.1 - 0.031 14.7 0.5 6 7.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 KNZ80652.1 - 0.031 13.9 1.2 8.9 5.9 0.0 2.8 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.20 KNZ80652.1 - 0.033 13.6 0.1 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 KNZ80652.1 - 0.037 13.2 0.4 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 TrwB_AAD_bind PF10412.4 KNZ80652.1 - 0.055 12.0 1.5 5.4 5.5 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 KNZ80652.1 - 0.059 12.8 1.5 1.6 8.1 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 KNZ80652.1 - 0.064 12.9 0.4 6.8 6.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 KNZ80652.1 - 0.076 11.9 1.4 2.1 7.2 0.0 2.6 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 KNZ80652.1 - 0.082 12.6 1.5 2 8.1 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain Pox_A32 PF04665.7 KNZ80652.1 - 0.13 11.5 1.9 3.8 6.7 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein KaiC PF06745.8 KNZ80652.1 - 0.15 11.1 1.5 2.4 7.2 0.1 2.6 3 0 0 3 3 2 0 KaiC Adeno_IVa2 PF02456.10 KNZ80652.1 - 0.17 10.5 0.1 6 5.4 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Dynamin_N PF00350.18 KNZ80652.1 - 0.2 11.4 0.9 9 6.0 0.1 2.5 2 0 0 2 2 2 0 Dynamin family DEAD PF00270.24 KNZ80652.1 - 0.21 11.0 2.5 19 4.7 0.0 3.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase RecA PF00154.16 KNZ80652.1 - 0.25 10.3 0.1 3.3 6.7 0.0 2.1 2 0 0 2 2 2 0 recA bacterial DNA recombination protein ResIII PF04851.10 KNZ80652.1 - 0.34 10.7 0.6 54 3.5 0.1 3.2 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit AIG1 PF04548.11 KNZ80652.1 - 1.3 8.0 2.3 15 4.6 0.2 2.8 3 0 0 3 3 2 0 AIG1 family Pex14_N PF04695.8 KNZ80653.1 - 0.026 14.5 1.8 0.046 13.7 1.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1180 PF06679.7 KNZ80653.1 - 0.027 14.3 0.5 0.05 13.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SSP160 PF06933.6 KNZ80653.1 - 0.032 12.2 7.0 0.042 11.8 4.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1515 PF07439.6 KNZ80653.1 - 0.049 13.4 0.1 0.078 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Med13_C PF06333.7 KNZ80653.1 - 0.092 11.2 6.0 0.12 10.8 4.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Asp PF00026.18 KNZ80654.1 - 1.4e-47 162.4 13.0 2.9e-47 161.4 9.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNZ80654.1 - 3.2e-07 30.4 4.1 3.9e-05 23.6 1.9 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KNZ80654.1 - 0.0014 19.0 6.2 0.026 15.0 1.0 3.0 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 KNZ80654.1 - 0.0024 17.4 0.2 0.012 15.2 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal ADH_zinc_N PF00107.21 KNZ80654.1 - 0.031 13.8 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RNase_H PF00075.19 KNZ80655.1 - 3.9e-22 79.0 0.0 9.9e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 RNase H FluMu_gp41 PF10109.4 KNZ80655.1 - 0.092 12.6 0.0 19 5.2 0.0 2.5 2 0 0 2 2 2 0 Mu-like prophage FluMu protein gp41 DUF4378 PF14309.1 KNZ80655.1 - 0.24 11.4 1.9 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) Asp PF00026.18 KNZ80657.1 - 3.7e-44 151.2 11.7 1.1e-43 149.6 8.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNZ80657.1 - 5e-07 29.8 3.2 8.4e-06 25.8 1.1 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KNZ80657.1 - 0.042 13.3 1.3 0.14 11.7 0.1 2.4 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KNZ80657.1 - 0.061 13.8 7.6 0.092 13.2 0.6 3.2 3 0 0 3 3 3 0 Aspartyl protease Myosin_head PF00063.16 KNZ80659.1 - 2.2e-224 746.5 0.6 3.8e-224 745.7 0.4 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KNZ80659.1 - 2e-38 131.6 0.1 4e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 Myosin tail AAA_22 PF13401.1 KNZ80659.1 - 0.0035 17.4 0.0 0.012 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Hpr_kinase_C PF07475.7 KNZ80659.1 - 0.0096 15.2 0.6 3.3 6.9 0.0 2.6 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 KNZ80659.1 - 0.02 14.0 0.0 0.05 12.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 KNZ80659.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 KNZ80659.1 - 0.042 13.5 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 KNZ80659.1 - 0.045 14.5 0.0 0.22 12.3 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KNZ80659.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Ank_5 PF13857.1 KNZ80660.1 - 7.6e-11 41.8 0.1 1.5e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KNZ80660.1 - 9.8e-11 41.8 0.1 1.3e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ80660.1 - 1.8e-09 36.8 0.5 1.3e-05 24.7 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 KNZ80660.1 - 1.3e-08 34.2 0.1 0.00028 20.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 KNZ80660.1 - 2.1e-05 24.8 0.0 0.003 18.0 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) PPR_1 PF12854.2 KNZ80660.1 - 0.03 13.7 0.2 0.062 12.7 0.1 1.5 1 0 0 1 1 1 0 PPR repeat PPR PF01535.15 KNZ80660.1 - 0.039 13.9 0.1 0.085 12.8 0.1 1.6 1 0 0 1 1 1 0 PPR repeat UNC45-central PF11701.3 KNZ80661.1 - 1.4e-07 31.3 0.0 4.1e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Phage_CRI PF05144.9 KNZ80661.1 - 0.061 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Phage replication protein CRI HEAT PF02985.17 KNZ80661.1 - 0.38 10.9 8.5 49 4.3 0.0 5.2 6 0 0 6 6 6 0 HEAT repeat Gcd10p PF04189.8 KNZ80662.1 - 6.6e-70 235.6 0.0 9.5e-69 231.7 0.0 2.0 1 1 0 1 1 1 1 Gcd10p family PXA PF02194.10 KNZ80663.1 - 1.8e-44 151.5 1.0 1.5e-43 148.5 0.0 3.0 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 KNZ80663.1 - 8.4e-28 96.7 4.9 1.1e-27 96.3 0.0 3.1 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 KNZ80663.1 - 1.1e-19 70.2 0.0 2.1e-18 66.1 0.0 2.6 2 0 0 2 2 2 1 PX domain RGS PF00615.14 KNZ80663.1 - 3.7e-10 39.9 0.3 9.9e-10 38.5 0.2 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain Mito_carr PF00153.22 KNZ80664.1 - 4.7e-53 176.8 0.8 6e-19 67.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cellulase PF00150.13 KNZ80665.1 - 8.6e-16 57.9 0.5 1.7e-15 56.9 0.3 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) UDPGP PF01704.13 KNZ80666.1 - 1.1e-47 162.4 0.0 1.5e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KNZ80666.1 - 0.024 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Taxilin PF09728.4 KNZ80667.1 - 2.3e-13 49.9 39.1 9.5e-08 31.4 13.5 2.7 2 1 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.3 KNZ80667.1 - 2.7e-07 30.1 0.9 0.0087 15.7 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like PhyH PF05721.8 KNZ80667.1 - 1.7 8.6 9.6 0.29 11.1 0.3 3.0 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) UPF0242 PF06785.6 KNZ80667.1 - 9.6 4.7 23.5 1.2 7.6 6.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) BRCA-2_OB1 PF09103.5 KNZ80668.1 - 4.1e-25 87.7 0.0 8e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 KNZ80668.1 - 1.5e-05 24.6 0.1 2.6e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 BRCA2, helical Val_tRNA-synt_C PF10458.4 KNZ80668.1 - 0.0044 17.0 0.0 0.016 15.2 0.0 2.0 1 1 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm Peptidase_M16_C PF05193.16 KNZ80669.1 - 1.4e-28 99.8 0.0 2.6e-28 98.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KNZ80669.1 - 2.7e-21 75.9 0.0 4.1e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Ceramidase PF05875.7 KNZ80670.1 - 3.1e-61 206.8 5.3 3.5e-61 206.6 3.7 1.0 1 0 0 1 1 1 1 Ceramidase Arv1 PF04161.8 KNZ80670.1 - 0.00032 20.6 0.4 0.00062 19.7 0.3 1.4 1 0 0 1 1 1 1 Arv1-like family DUF457 PF04307.9 KNZ80670.1 - 5.5 6.3 9.1 31 3.8 6.3 2.1 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) EF_TS PF00889.14 KNZ80671.1 - 1.1e-20 73.9 0.0 1.2e-18 67.2 0.0 2.2 1 1 1 2 2 2 2 Elongation factor TS UBA PF00627.26 KNZ80671.1 - 2.9e-07 30.1 0.1 7.3e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 KNZ80671.1 - 0.11 12.0 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain Gar1 PF04410.9 KNZ80672.1 - 6.9e-32 110.0 0.1 6.9e-32 110.0 0.1 2.2 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Ribonuclease_T2 PF00445.13 KNZ80673.1 - 4.2e-43 147.1 0.1 6.3e-43 146.5 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Apo-CIII PF05778.7 KNZ80673.1 - 0.22 10.9 2.3 0.27 10.6 0.1 2.1 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) SAS4 PF15460.1 KNZ80674.1 - 6.4e-06 25.9 3.9 6.4e-06 25.9 2.7 1.8 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.1 KNZ80674.1 - 0.00033 21.0 0.3 0.00033 21.0 0.2 3.5 3 1 0 3 3 3 1 PEHE domain DUF2927 PF11150.3 KNZ80675.1 - 0.65 9.6 5.2 1.2 8.7 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2927) zf-DHHC PF01529.15 KNZ80676.1 - 2.2e-43 147.6 5.5 2.2e-43 147.6 3.8 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Bromodomain PF00439.20 KNZ80677.1 - 1.1e-39 134.2 4.2 2.2e-19 69.1 0.5 2.8 2 0 0 2 2 2 2 Bromodomain FlgM PF04316.8 KNZ80677.1 - 0.0049 16.7 3.8 0.3 11.0 0.0 3.3 3 0 0 3 3 3 2 Anti-sigma-28 factor, FlgM zf-CCCH PF00642.19 KNZ80677.1 - 0.68 9.6 1.8 1.2 8.8 1.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FA_desaturase PF00487.19 KNZ80678.1 - 6.6e-10 38.8 4.8 1e-09 38.2 3.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KNZ80678.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CutC PF03932.9 KNZ80679.1 - 6.9e-57 191.9 0.0 8.3e-57 191.7 0.0 1.1 1 0 0 1 1 1 1 CutC family Glyco_transf_22 PF03901.12 KNZ80681.1 - 5.3e-79 266.1 21.2 9.1e-79 265.3 14.7 1.4 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Histone PF00125.19 KNZ80682.1 - 7.8e-14 51.5 0.1 9.4e-14 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNZ80682.1 - 2.8e-05 24.2 0.0 3.6e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KNZ80682.1 - 7.8e-05 22.5 0.1 0.00011 22.0 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KNZ80682.1 - 0.00067 19.6 0.1 0.0013 18.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KNZ80682.1 - 0.048 12.9 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KNZ80682.1 - 0.096 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Thioredoxin PF00085.15 KNZ80683.1 - 2.6e-27 94.5 0.0 3.6e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KNZ80683.1 - 4.4e-07 29.9 0.0 0.00046 20.2 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KNZ80683.1 - 7.2e-06 26.1 0.1 6.8e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KNZ80683.1 - 0.00011 21.8 0.1 0.0002 21.0 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KNZ80683.1 - 0.00016 21.2 0.0 0.00022 20.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KNZ80683.1 - 0.00055 19.9 0.1 0.0011 18.8 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KNZ80683.1 - 0.0036 16.8 0.1 0.008 15.7 0.0 1.6 1 1 1 2 2 2 1 Redoxin TraF PF13728.1 KNZ80683.1 - 0.018 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein DIM1 PF02966.11 KNZ80683.1 - 0.057 12.9 0.0 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF953 PF06110.6 KNZ80683.1 - 0.082 12.3 0.1 0.42 10.0 0.1 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) dsrm PF00035.20 KNZ80684.1 - 5.5e-08 33.2 0.0 9.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 KNZ80684.1 - 0.00031 20.6 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KNZ80684.1 - 0.00052 20.4 0.0 0.0007 20.0 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease III domain Nucleoplasmin PF03066.10 KNZ80685.1 - 0.17 11.3 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin Pyrophosphatase PF00719.14 KNZ80686.1 - 1.3e-53 180.6 0.1 1.8e-53 180.1 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Spc97_Spc98 PF04130.8 KNZ80687.1 - 1.9e-71 241.0 0.0 3.7e-71 240.0 0.0 1.4 2 0 0 2 2 2 1 Spc97 / Spc98 family Nup96 PF12110.3 KNZ80687.1 - 0.032 13.3 0.6 6.8 5.7 0.0 2.6 2 1 1 3 3 3 0 Nuclear protein 96 Fucose_iso_C PF02952.12 KNZ80687.1 - 0.1 12.1 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain RabGAP-TBC PF00566.13 KNZ80688.1 - 7.1e-26 91.0 0.0 1.3e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Hex_IIIa PF02455.11 KNZ80688.1 - 0.92 8.1 3.0 1.4 7.4 2.1 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) O-FucT PF10250.4 KNZ80689.1 - 1.9e-08 33.8 0.0 2.4e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase PgaD PF13994.1 KNZ80690.1 - 0.17 11.3 4.0 0.51 9.8 0.5 2.9 2 1 1 3 3 3 0 PgaD-like protein ApbA_C PF08546.6 KNZ80691.1 - 5.9e-38 129.6 0.0 1.6e-37 128.3 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KNZ80691.1 - 3.8e-22 78.3 0.1 6.4e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA rRNA_methylase PF06962.7 KNZ80691.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative rRNA methylase Aldo_ket_red PF00248.16 KNZ80692.1 - 1.6e-30 105.9 0.0 2e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RNase_P_pop3 PF08228.6 KNZ80693.1 - 9.1e-15 54.8 0.1 5.7e-10 39.2 0.0 2.4 2 0 0 2 2 2 2 RNase P subunit Pop3 Arrestin_C PF02752.17 KNZ80694.1 - 1.1e-13 51.4 0.0 3.5e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain FR47 PF08445.5 KNZ80694.1 - 2.5e-07 30.3 0.0 6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 KNZ80694.1 - 1.2e-06 28.4 0.0 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KNZ80694.1 - 1.9e-05 24.7 0.0 4.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNZ80694.1 - 0.00016 21.7 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KNZ80694.1 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KNZ80694.1 - 0.017 14.9 0.0 0.046 13.5 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF605 PF04652.11 KNZ80695.1 - 1.8e-71 241.5 5.7 2.1e-71 241.3 4.0 1.0 1 0 0 1 1 1 1 Vta1 like FliD_N PF02465.13 KNZ80696.1 - 0.049 13.9 1.0 0.12 12.7 0.7 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus ALIX_LYPXL_bnd PF13949.1 KNZ80696.1 - 0.077 11.9 2.3 5 5.9 0.1 2.1 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Flg_hook PF02120.11 KNZ80696.1 - 0.12 12.0 0.5 1.3 8.7 0.1 2.2 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Ribonucleas_3_3 PF14622.1 KNZ80701.1 - 1.7e-15 57.1 0.0 2.1e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Lipase_GDSL PF00657.17 KNZ80702.1 - 4.1e-09 36.5 5.7 1.1e-08 35.2 3.9 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KNZ80702.1 - 3.8e-06 27.1 8.4 5.6e-06 26.6 5.8 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KNZ80703.1 - 1.1e-11 44.9 0.5 1.5e-11 44.5 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KNZ80703.1 - 3.6e-08 33.7 0.4 4.8e-08 33.3 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SAGA-Tad1 PF12767.2 KNZ80704.1 - 9.1e-32 110.6 0.1 3.5e-31 108.7 0.0 2.0 2 1 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 KNZ80704.1 - 0.013 14.8 0.3 0.022 14.0 0.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family zf-CCCH PF00642.19 KNZ80704.1 - 0.043 13.5 0.6 0.13 11.9 0.4 1.8 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mus7 PF09462.5 KNZ80705.1 - 6.5e-36 124.3 0.0 1.1e-35 123.5 0.0 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family DUF106 PF01956.11 KNZ80705.1 - 6.4 6.2 5.2 3.3 7.2 1.7 1.9 2 0 0 2 2 2 0 Integral membrane protein DUF106 Dicty_REP PF05086.7 KNZ80705.1 - 6.5 4.3 4.3 10 3.7 3.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zn_Tnp_IS1595 PF12760.2 KNZ80706.1 - 0.021 14.6 1.6 0.049 13.4 1.1 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-RING_3 PF14369.1 KNZ80706.1 - 0.14 12.1 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 zinc-finger YdjO PF14169.1 KNZ80706.1 - 0.17 11.3 0.4 0.94 8.9 0.0 2.0 2 0 0 2 2 2 0 Cold-inducible protein YdjO zf-TFIIB PF13453.1 KNZ80706.1 - 2.5 7.3 6.5 0.32 10.2 1.0 2.1 2 1 0 2 2 2 0 Transcription factor zinc-finger RNase_H PF00075.19 KNZ80707.1 - 6.3e-05 23.3 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 KNZ80707.1 - 0.0019 17.8 0.1 0.0035 16.9 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase PAT1 PF09770.4 KNZ80710.1 - 9.7e-143 477.2 30.5 1.2e-142 476.9 21.1 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 hDGE_amylase PF14701.1 KNZ80711.1 - 1.8e-136 455.3 0.0 7.9e-136 453.3 0.0 1.9 1 1 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KNZ80711.1 - 1.4e-114 382.6 0.0 2e-114 382.1 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KNZ80711.1 - 3e-84 282.2 0.0 5.4e-84 281.4 0.0 1.4 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme Mito_carr PF00153.22 KNZ80711.1 - 7.6e-69 227.4 2.6 5.5e-23 80.4 0.0 3.5 2 1 1 3 3 3 3 Mitochondrial carrier protein hGDE_N PF14699.1 KNZ80711.1 - 3.8e-17 61.9 0.0 9.1e-17 60.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Choline_sulf_C PF12411.3 KNZ80711.1 - 0.083 12.7 0.1 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal Vip3A_N PF12495.3 KNZ80711.1 - 0.39 10.3 0.0 0.78 9.4 0.0 1.4 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal RNase_H PF00075.19 KNZ80712.1 - 6.3e-08 33.0 0.3 2.8e-07 30.9 0.0 2.2 3 0 0 3 3 3 1 RNase H rve PF00665.21 KNZ80712.1 - 0.00041 20.4 0.0 0.006 16.6 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain Asp_protease_2 PF13650.1 KNZ80712.1 - 0.14 12.6 0.0 0.84 10.1 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease Zn_Tnp_IS1595 PF12760.2 KNZ80712.1 - 0.87 9.4 6.6 0.31 10.8 2.1 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain ARF7EP_C PF14949.1 KNZ80713.1 - 0.14 12.5 3.8 0.46 10.9 2.6 1.8 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Myb_DNA-bind_3 PF12776.2 KNZ80714.1 - 0.052 14.1 0.2 0.16 12.6 0.2 1.8 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Endothelin PF00322.12 KNZ80716.1 - 0.66 9.2 4.3 1.3 8.3 2.9 1.5 1 0 0 1 1 1 0 Endothelin family Imm22 PF15592.1 KNZ80719.1 - 0.044 14.0 0.7 0.11 12.7 0.5 1.6 1 0 0 1 1 1 0 Immunity protein 22 Terpene_synth_C PF03936.11 KNZ80720.1 - 4.7e-11 42.4 0.0 6.8e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF2600 PF10776.4 KNZ80720.1 - 0.019 13.8 0.1 4.3 6.0 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2600) zf-H2C2_2 PF13465.1 KNZ80721.1 - 1.1e-07 31.8 11.9 2.4e-07 30.7 0.3 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KNZ80721.1 - 1.9e-05 24.7 11.2 0.041 14.2 1.9 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ80721.1 - 0.00011 22.3 11.6 0.3 11.5 0.4 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KNZ80721.1 - 0.11 12.8 0.5 0.11 12.8 0.3 3.5 3 1 0 3 3 3 0 C2H2-type zinc-finger domain RVP_2 PF08284.6 KNZ80722.1 - 0.058 13.3 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Terpene_synth_C PF03936.11 KNZ80723.1 - 1.6e-11 44.0 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF2600 PF10776.4 KNZ80723.1 - 0.027 13.3 0.0 4.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2600) Fer2_3 PF13085.1 KNZ80724.1 - 3.3e-33 113.7 0.0 5.1e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KNZ80724.1 - 5.2e-11 42.7 7.5 5.2e-11 42.7 5.2 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KNZ80724.1 - 1.2e-08 34.8 5.3 1.2e-08 34.8 3.7 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KNZ80724.1 - 6.6e-05 22.6 5.0 6.6e-05 22.6 3.5 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KNZ80724.1 - 7.6e-05 23.0 2.8 7.6e-05 23.0 1.9 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KNZ80724.1 - 0.00037 20.6 4.9 0.042 14.1 0.6 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 KNZ80724.1 - 0.00052 20.3 4.1 0.00052 20.3 2.8 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 KNZ80724.1 - 0.003 17.2 0.3 0.003 17.2 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 KNZ80724.1 - 1.3 9.6 6.9 1.3 9.6 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain SecY PF00344.15 KNZ80725.1 - 2.8e-95 319.1 9.6 3.5e-95 318.8 6.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KNZ80725.1 - 1.7e-19 69.0 0.2 6e-19 67.2 0.1 2.0 2 0 0 2 2 2 1 Plug domain of Sec61p ubiquitin PF00240.18 KNZ80726.1 - 1.6e-34 117.0 0.8 2.1e-34 116.7 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 KNZ80726.1 - 3.4e-28 96.9 4.3 5.4e-28 96.3 3.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 KNZ80726.1 - 5.5e-20 70.8 0.7 8.1e-20 70.2 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KNZ80726.1 - 7.4e-06 26.1 0.1 2.7e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KNZ80726.1 - 0.0047 16.6 0.0 0.0091 15.7 0.0 1.5 1 1 1 2 2 2 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KNZ80726.1 - 0.0048 16.7 0.1 0.009 15.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KNZ80726.1 - 0.016 15.3 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain zf-DHHC PF01529.15 KNZ80726.1 - 0.22 10.9 1.3 0.31 10.4 0.9 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Fer2_3 PF13085.1 KNZ80726.1 - 0.33 10.7 1.6 0.85 9.4 0.7 1.9 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain MFS_1 PF07690.11 KNZ80727.1 - 8.3e-21 74.0 41.7 1.6e-12 46.8 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FA_desaturase PF00487.19 KNZ80728.1 - 1e-11 44.7 6.9 1e-11 44.7 4.8 2.1 1 1 1 2 2 2 1 Fatty acid desaturase 4HBT PF03061.17 KNZ80729.1 - 1.6e-08 34.5 0.1 2.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily zf-CCHC PF00098.18 KNZ80731.1 - 0.013 15.3 1.4 0.02 14.8 1.0 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 KNZ80731.1 - 0.024 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Zinc knuckle RNase_H PF00075.19 KNZ80733.1 - 2e-21 76.7 0.1 3.1e-20 72.8 0.0 2.8 3 0 0 3 3 3 1 RNase H zf-RVT PF13966.1 KNZ80733.1 - 6.6e-05 23.1 0.1 6.6e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RVP_2 PF08284.6 KNZ80734.1 - 0.0043 16.9 0.2 0.0076 16.1 0.0 1.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Spo7 PF03907.8 KNZ80735.1 - 8.3e-10 38.6 7.1 2.6e-09 37.0 0.4 2.8 2 1 0 2 2 2 2 Spo7-like protein DnaJ PF00226.26 KNZ80736.1 - 3e-19 68.5 0.3 6.6e-19 67.4 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Amidase PF01425.16 KNZ80737.1 - 6.3e-80 269.1 0.0 1.1e-79 268.3 0.0 1.4 1 1 0 1 1 1 1 Amidase Oxidored_molyb PF00174.14 KNZ80738.1 - 4e-51 172.8 0.0 6.3e-51 172.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KNZ80738.1 - 1.9e-48 163.4 0.0 3.2e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.19 KNZ80738.1 - 8.5e-23 80.3 0.0 2e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KNZ80738.1 - 2.6e-21 76.2 0.0 5.7e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KNZ80738.1 - 1.4e-17 63.2 0.0 3.1e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KNZ80738.1 - 0.00033 20.5 0.0 0.001 19.0 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain CBM_4_9 PF02018.12 KNZ80738.1 - 0.069 13.1 0.0 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Carbohydrate binding domain MFS_1 PF07690.11 KNZ80739.1 - 1.6e-29 102.7 13.5 1.6e-29 102.7 9.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KNZ80739.1 - 0.0041 16.8 0.3 1 9.1 0.0 3.0 2 0 0 2 2 2 2 MFS_1 like family NIR_SIR PF01077.17 KNZ80740.1 - 2.2e-32 111.5 0.5 5.3e-32 110.3 0.1 1.9 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 KNZ80740.1 - 2.2e-21 76.6 0.0 3.9e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 KNZ80740.1 - 1.1e-18 66.9 0.0 3.2e-18 65.3 0.0 1.9 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.10 KNZ80740.1 - 3.9e-13 49.2 4.4 3.7e-10 39.7 1.4 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 KNZ80740.1 - 6.2e-13 48.1 0.0 1.8e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox PF00070.22 KNZ80740.1 - 1.2e-11 44.8 0.1 3.3e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KNZ80740.1 - 1.2e-11 43.9 0.1 4.7e-11 42.1 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 KNZ80740.1 - 0.0047 17.0 0.1 0.1 12.6 0.0 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KNZ80740.1 - 0.047 12.6 0.0 0.093 11.6 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Amidase PF01425.16 KNZ80741.1 - 3.1e-76 257.0 0.1 4.7e-76 256.4 0.0 1.3 1 1 0 1 1 1 1 Amidase TGT PF01702.13 KNZ80743.1 - 8.3e-27 93.9 0.0 1.4e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MFS_2 PF13347.1 KNZ80744.1 - 1.1e-13 50.4 10.8 1.1e-13 50.4 7.5 3.3 3 1 0 3 3 3 2 MFS/sugar transport protein Pkinase PF00069.20 KNZ80745.1 - 2.2e-70 236.8 0.0 3e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ80745.1 - 6e-33 114.0 0.0 8.7e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ80745.1 - 2.8e-06 26.5 0.0 4.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KNZ80745.1 - 2.1e-05 23.6 0.0 5.1e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ80745.1 - 0.0039 16.9 0.1 0.013 15.2 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KNZ80745.1 - 0.021 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DNA_pol_A_exo1 PF01612.15 KNZ80746.1 - 5.6e-19 68.2 0.0 1.1e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease HMGL-like PF00682.14 KNZ80747.1 - 3.5e-37 128.3 0.0 4.7e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 HMGL-like Abhydrolase_6 PF12697.2 KNZ80748.1 - 2.5e-22 79.8 0.0 3e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ80748.1 - 0.0045 16.7 0.0 0.0086 15.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family JmjC PF02373.17 KNZ80749.1 - 2.7e-09 37.2 0.1 1.5e-08 34.9 0.1 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase RNase_H PF00075.19 KNZ80751.1 - 5.8e-06 26.6 0.0 0.012 15.9 0.0 2.5 3 0 0 3 3 3 2 RNase H RVT_3 PF13456.1 KNZ80751.1 - 0.049 13.4 0.0 0.19 11.5 0.0 2.0 1 0 0 1 1 1 0 Reverse transcriptase-like Herpes_Helicase PF02689.9 KNZ80755.1 - 1.6e-08 32.8 0.0 1.8e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ80755.1 - 4.2e-05 23.6 0.0 5.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain HMG_box PF00505.14 KNZ80757.1 - 2e-10 40.7 0.1 4.1e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KNZ80757.1 - 0.00037 20.8 0.0 0.001 19.4 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KNZ80757.1 - 0.057 13.2 0.3 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Fungal_trans PF04082.13 KNZ80758.1 - 1.3e-13 50.4 2.2 2e-13 49.8 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KNZ80758.1 - 1.8e-07 31.0 15.3 0.00042 20.4 1.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ80758.1 - 1.7e-06 27.9 22.3 7.7e-06 25.8 1.7 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KNZ80758.1 - 4.9e-05 23.4 4.4 4.9e-05 23.4 3.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 KNZ80758.1 - 0.0073 16.4 4.5 0.024 14.8 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KNZ80758.1 - 0.026 14.6 2.0 0.74 10.0 0.1 2.9 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KNZ80758.1 - 0.88 9.3 7.6 4.5 7.0 1.1 2.7 1 1 1 2 2 2 0 BED zinc finger TPT PF03151.11 KNZ80759.1 - 0.36 10.4 8.8 0.68 9.5 6.1 1.4 1 0 0 1 1 1 0 Triose-phosphate Transporter family SOBP PF15279.1 KNZ80760.1 - 0.0053 17.1 0.4 0.01 16.2 0.3 1.6 1 0 0 1 1 1 1 Sine oculis-binding protein PKI PF02827.11 KNZ80760.1 - 0.12 12.4 0.2 0.27 11.3 0.2 1.5 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor RVP_2 PF08284.6 KNZ80761.1 - 0.031 14.2 0.2 0.045 13.6 0.1 1.4 1 1 0 1 1 1 0 Retroviral aspartyl protease RVP_2 PF08284.6 KNZ80763.1 - 7e-05 22.7 0.0 0.0025 17.7 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KNZ80763.1 - 0.0013 19.2 0.0 0.0059 17.0 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 KNZ80763.1 - 0.006 16.3 0.0 0.043 13.6 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-C2H2 PF00096.21 KNZ80765.1 - 2.8e-08 33.6 9.9 0.00012 22.1 1.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KNZ80765.1 - 6e-08 32.6 6.9 0.00077 19.6 0.0 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KNZ80765.1 - 0.00098 19.2 11.6 0.14 12.5 1.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KNZ80765.1 - 0.019 15.1 3.4 0.03 14.4 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KNZ80765.1 - 0.039 14.1 0.8 0.039 14.1 0.6 2.7 2 1 1 3 3 3 0 Zinc-finger of C2H2 type FYDLN_acid PF09538.5 KNZ80765.1 - 0.044 14.3 0.7 5.6 7.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Xol-1_GHMP-like PF09109.5 KNZ80765.1 - 0.22 11.5 0.2 2.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Switch protein XOL-1, GHMP-like zf-C2HC_2 PF13913.1 KNZ80765.1 - 1.9 8.2 5.8 4.1 7.1 0.5 2.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type AhpC-TSA_2 PF13911.1 KNZ80766.1 - 2.3e-21 75.8 0.0 3.3e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KNZ80766.1 - 7.6e-06 25.6 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KNZ80766.1 - 6.2e-05 22.5 0.0 9.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin EI24 PF07264.6 KNZ80767.1 - 2.4e-06 27.1 3.1 3.5e-06 26.6 2.2 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) zf-MYND PF01753.13 KNZ80768.1 - 2.8e-07 30.3 16.3 5.2e-07 29.4 11.3 1.5 1 1 0 1 1 1 1 MYND finger DUF3824 PF12868.2 KNZ80768.1 - 0.036 15.0 7.4 0.066 14.1 5.2 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Glyco_hydro_16 PF00722.16 KNZ80769.1 - 2e-06 27.1 0.0 4.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PAP2 PF01569.16 KNZ80770.1 - 0.78 9.4 6.5 3.7 7.2 2.9 2.4 2 1 0 2 2 2 0 PAP2 superfamily Uricase PF01014.13 KNZ80771.1 - 1.1e-60 203.6 0.4 5.6e-34 117.1 0.3 2.3 2 1 0 2 2 2 2 Uricase Nuc_sug_transp PF04142.10 KNZ80772.1 - 3.8e-09 36.0 1.4 5.3e-09 35.5 0.9 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 KNZ80772.1 - 1.2e-07 31.7 20.7 2.7e-06 27.4 3.4 3.1 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KNZ80772.1 - 3.2e-06 26.3 5.5 4.3e-06 25.8 3.8 1.2 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 KNZ80772.1 - 1.7e-05 24.9 3.5 1.7e-05 24.9 2.4 2.7 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Pox_A14 PF05767.7 KNZ80772.1 - 0.0051 16.7 3.7 0.58 10.1 0.1 2.6 2 0 0 2 2 2 2 Poxvirus virion envelope protein A14 TPT PF03151.11 KNZ80772.1 - 0.0061 16.2 17.5 0.0077 15.8 0.7 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF914 PF06027.7 KNZ80772.1 - 0.24 10.1 12.7 2.1 7.1 8.8 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) DUF1469 PF07332.6 KNZ80772.1 - 4.1 7.1 9.0 0.36 10.5 1.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) ETRAMP PF09716.5 KNZ80773.1 - 0.0014 18.5 0.0 0.002 18.0 0.0 1.4 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) p450 PF00067.17 KNZ80774.1 - 1.9e-38 132.1 0.0 3.6e-38 131.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF1741 PF08427.5 KNZ80774.1 - 0.028 13.8 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) LSM PF01423.17 KNZ80775.1 - 8.5e-14 50.8 0.5 1e-13 50.5 0.4 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KNZ80775.1 - 7.7e-06 25.7 0.2 1.1e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain UPF0016 PF01169.14 KNZ80776.1 - 2.5e-43 146.0 19.5 9.6e-22 76.9 4.5 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 KNZ80776.1 - 0.01 15.2 3.9 0.031 13.6 0.0 2.5 2 1 0 2 2 2 0 Integral membrane protein TerC family DUF2407_C PF13373.1 KNZ80776.1 - 0.047 13.6 0.1 0.047 13.6 0.1 1.6 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF2208 PF09973.4 KNZ80776.1 - 0.11 11.7 0.0 0.41 9.8 0.0 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF4131 PF13567.1 KNZ80776.1 - 0.61 9.4 4.8 3.9 6.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Abhydrolase_6 PF12697.2 KNZ80777.1 - 1.6e-21 77.2 0.0 1.9e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ80777.1 - 1.4e-06 28.0 0.0 3.1e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KNZ80777.1 - 0.003 16.5 0.0 0.0081 15.0 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 KNZ80777.1 - 0.0067 16.0 0.0 0.069 12.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold GST_N_3 PF13417.1 KNZ80778.1 - 2.4e-12 46.9 0.0 6e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KNZ80778.1 - 7.5e-08 32.2 0.0 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KNZ80778.1 - 0.001 18.9 0.1 0.0017 18.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KNZ80778.1 - 0.0012 18.7 0.1 0.0022 17.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PAS_4 PF08448.5 KNZ80778.1 - 0.015 15.2 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 PAS fold GST_C_3 PF14497.1 KNZ80778.1 - 0.091 13.2 0.1 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TRI5 PF06330.6 KNZ80779.1 - 8.9e-15 54.2 0.6 1.1e-14 53.8 0.4 1.2 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF2947 PF11163.3 KNZ80780.1 - 0.067 12.7 0.6 0.13 11.8 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2947) RVP_2 PF08284.6 KNZ80781.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Aminotran_3 PF00202.16 KNZ80782.1 - 8e-101 337.2 0.0 9.6e-101 337.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KNZ80782.1 - 7.7e-07 28.3 0.0 1.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II TRI5 PF06330.6 KNZ80783.1 - 2.4e-12 46.2 0.6 3.3e-12 45.7 0.4 1.2 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) gag-asp_proteas PF13975.1 KNZ80784.1 - 0.0014 18.3 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ80784.1 - 0.023 15.2 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Ribosomal_S6e PF01092.14 KNZ80786.1 - 6.1e-59 197.2 0.1 9.5e-59 196.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6e Ribosomal_S13_N PF08069.7 KNZ80787.1 - 7.8e-30 102.5 0.1 1.6e-29 101.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KNZ80787.1 - 5.3e-23 80.5 0.1 7e-23 80.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 KNZ80787.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.6 1 1 0 1 1 1 0 'Paired box' domain Pex24p PF06398.6 KNZ80789.1 - 7.3e-16 57.9 16.0 1.6e-11 43.5 0.5 2.4 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin LRR_8 PF13855.1 KNZ80793.1 - 0.054 13.2 2.5 0.67 9.7 0.9 3.3 3 1 0 3 3 3 0 Leucine rich repeat DUF3402 PF11882.3 KNZ80794.1 - 0.97 8.4 8.2 1.7 7.6 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) BTB PF00651.26 KNZ80797.1 - 0.096 12.6 0.1 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain zf-C3HC4_3 PF13920.1 KNZ80798.1 - 1.8e-10 40.3 4.9 3.2e-10 39.5 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ80798.1 - 2.3e-07 30.7 8.5 2.3e-07 30.7 5.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ80798.1 - 9.8e-07 28.4 7.5 2.3e-06 27.2 5.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KNZ80798.1 - 1.6e-06 27.8 8.1 1.6e-06 27.8 5.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KNZ80798.1 - 2.7e-06 26.9 7.5 5.4e-06 25.9 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KNZ80798.1 - 0.3 10.8 7.3 0.24 11.1 3.1 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KNZ80798.1 - 0.4 10.6 12.5 5.1 7.0 8.9 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF1644 PF07800.7 KNZ80798.1 - 2 8.2 7.3 19 5.0 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) BTB PF00651.26 KNZ80800.1 - 9.1e-06 25.6 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ku PF02735.11 KNZ80802.1 - 2.2e-30 105.5 0.3 8.5e-25 87.3 0.0 2.3 2 0 0 2 2 2 2 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KNZ80802.1 - 8.6e-21 74.3 0.0 1.4e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 KNZ80802.1 - 1.1e-06 28.0 0.0 4.3e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 SAP domain Ku_C PF03730.9 KNZ80802.1 - 1.7e-05 25.2 0.0 4.6e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA_2 PF13519.1 KNZ80802.1 - 0.00034 20.7 0.0 0.00096 19.2 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KNZ80802.1 - 0.03 14.0 0.0 0.14 11.9 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain PTPA PF03095.10 KNZ80803.1 - 2.9e-87 292.6 0.0 3.4e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Orn_Arg_deC_N PF02784.11 KNZ80804.1 - 8.8e-69 231.4 0.0 1.2e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KNZ80804.1 - 1.4e-30 105.3 0.0 2.5e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Na_sulph_symp PF00939.14 KNZ80806.1 - 1.7e-27 96.4 28.3 4.7e-27 95.0 19.6 1.7 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.14 KNZ80806.1 - 8.3e-15 55.2 0.0 1.2e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 SPX domain CitMHS PF03600.11 KNZ80806.1 - 5.6e-13 48.2 27.0 5.6e-11 41.6 9.3 2.4 1 1 1 2 2 2 2 Citrate transporter F-box-like PF12937.2 KNZ80806.1 - 0.0022 17.6 0.5 0.0069 16.0 0.3 1.9 1 0 0 1 1 1 1 F-box-like Glutaredoxin PF00462.19 KNZ80807.1 - 1.3e-18 66.6 0.0 1.3e-16 60.3 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 KNZ80807.1 - 2.7e-15 55.9 0.0 7.7e-15 54.4 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 KNZ80807.1 - 7.5e-07 29.1 0.1 0.00059 19.8 0.0 3.1 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KNZ80807.1 - 0.00057 20.0 0.0 0.026 14.7 0.0 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.6 KNZ80807.1 - 0.0021 17.9 0.1 0.054 13.3 0.0 2.8 3 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE ArsC PF03960.10 KNZ80807.1 - 0.0084 16.1 0.0 0.032 14.2 0.0 2.0 2 0 0 2 2 2 1 ArsC family GST_N_3 PF13417.1 KNZ80807.1 - 0.065 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Sigma70_r4_2 PF08281.7 KNZ80807.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 TrbC_Ftype PF09673.5 KNZ80807.1 - 0.11 12.0 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Isochorismatase PF00857.15 KNZ80808.1 - 1.9e-15 57.2 0.0 2.6e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family PIG-X PF08320.7 KNZ80809.1 - 5.1e-25 87.9 0.0 6.4e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 Hus1 PF04005.7 KNZ80810.1 - 6.2e-80 268.2 1.5 7.1e-80 268.0 1.1 1.0 1 0 0 1 1 1 1 Hus1-like protein OTT_1508_deam PF14441.1 KNZ80811.1 - 0.00036 20.3 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase AIRC PF00731.15 KNZ80812.1 - 3.2e-64 214.7 1.7 8.9e-64 213.3 1.2 1.8 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 KNZ80812.1 - 6.1e-59 198.2 0.0 8.8e-59 197.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KNZ80812.1 - 2.9e-13 49.9 0.0 5.1e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KNZ80812.1 - 6.1e-06 25.2 0.0 6.2e-05 21.8 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 KNZ80812.1 - 0.0017 17.7 0.0 0.0038 16.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CoA_binding_2 PF13380.1 KNZ80812.1 - 0.28 11.3 1.7 44 4.2 0.0 3.5 3 1 1 4 4 4 0 CoA binding domain Pec_lyase_C PF00544.14 KNZ80813.1 - 2e-38 131.8 8.2 2.7e-38 131.4 5.7 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KNZ80813.1 - 0.00061 19.5 17.7 0.0081 15.9 12.1 2.4 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 KNZ80813.1 - 0.41 9.7 12.4 7.9 5.5 8.4 2.2 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Abhydrolase_6 PF12697.2 KNZ80814.1 - 3.5e-14 53.2 0.1 4.2e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ80814.1 - 0.0014 18.4 0.0 0.0036 17.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Costars PF14705.1 KNZ80815.1 - 1.2e-20 73.2 0.0 2.4e-20 72.2 0.0 1.5 1 1 0 1 1 1 1 Costars Borrelia_P83 PF05262.6 KNZ80816.1 - 8.2 4.5 14.2 12 3.9 9.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Exo_endo_phos PF03372.18 KNZ80817.1 - 2.9e-23 83.0 0.5 7.5e-23 81.7 0.4 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 KNZ80817.1 - 0.24 11.3 2.9 2.6 8.0 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat MFS_1 PF07690.11 KNZ80818.1 - 3.7e-17 62.0 13.7 3.7e-17 62.0 9.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 KNZ80818.1 - 9.6e-08 31.5 5.9 9.6e-08 31.5 4.1 2.4 2 1 0 2 2 2 1 Nodulin-like HMGL-like PF00682.14 KNZ80819.1 - 3.2e-47 161.1 0.0 4.5e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KNZ80819.1 - 4.3e-09 36.2 0.0 8.8e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain MFS_1 PF07690.11 KNZ80820.1 - 8.4e-40 136.5 33.1 8.4e-40 136.5 22.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ80820.1 - 2.3e-06 26.4 24.0 6.4e-05 21.7 16.6 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KNZ80820.1 - 6.1e-05 21.4 1.1 0.0001 20.6 0.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Npa1 PF11707.3 KNZ80821.1 - 5.9e-73 245.7 0.0 1.1e-72 244.8 0.0 1.4 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Cu-oxidase PF00394.17 KNZ80821.1 - 4.2e-39 133.9 1.1 6.1e-39 133.4 0.1 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KNZ80821.1 - 4.4e-30 104.0 2.5 4.8e-29 100.6 0.4 2.9 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KNZ80821.1 - 1.6e-29 101.9 1.0 2.9e-25 88.3 0.0 3.4 3 0 0 3 3 3 3 Multicopper oxidase Creb_binding PF09030.5 KNZ80821.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Creb binding Oxidored_FMN PF00724.15 KNZ80822.1 - 7.9e-100 334.1 0.0 9e-100 333.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family p450 PF00067.17 KNZ80823.1 - 5.7e-54 183.3 0.0 1.1e-53 182.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF1837 PF08878.6 KNZ80823.1 - 0.12 11.9 0.3 0.24 10.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) Mu-like_Pro PF10123.4 KNZ80824.1 - 0.028 13.8 1.3 0.037 13.4 0.9 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein APG6 PF04111.7 KNZ80824.1 - 0.47 9.4 11.5 0.77 8.7 8.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ERM PF00769.14 KNZ80824.1 - 0.59 9.6 14.4 1.6 8.1 10.1 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.7 KNZ80824.1 - 1.2 8.8 13.6 0.89 9.3 0.5 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF342 PF03961.8 KNZ80824.1 - 1.7 6.9 7.4 2.3 6.5 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MRP-L28 PF09812.4 KNZ80824.1 - 2 8.2 7.8 4.2 7.1 5.4 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 DUF972 PF06156.8 KNZ80824.1 - 2.7 8.4 8.5 3 8.2 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HD PF01966.17 KNZ80826.1 - 6.4e-13 48.7 0.0 2.1e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 HD domain Thiolase_C PF02803.13 KNZ80828.1 - 3.6e-11 42.5 0.0 7.9e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain Na_H_Exchanger PF00999.16 KNZ80830.1 - 3e-55 187.3 24.0 3.5e-55 187.0 16.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KNZ80830.1 - 0.43 10.5 3.9 3.4 7.6 0.3 2.7 2 0 0 2 2 2 0 YrhC-like protein Orn_Arg_deC_N PF02784.11 KNZ80833.1 - 1.1e-67 227.9 0.0 1.3e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KNZ80833.1 - 1.7e-29 101.8 0.0 2.7e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain F-box-like PF12937.2 KNZ80834.1 - 3.1e-05 23.5 0.1 9.8e-05 22.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like UbiA PF01040.13 KNZ80835.1 - 2e-16 60.0 1.1 2.1e-16 59.9 0.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4389 PF14333.1 KNZ80835.1 - 1.2 8.8 4.9 0.21 11.3 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Abhydrolase_6 PF12697.2 KNZ80836.1 - 3.1e-14 53.4 0.8 6.8e-14 52.2 0.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ80836.1 - 1.4e-12 47.5 0.0 2.2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KNZ80836.1 - 4.2e-05 23.1 0.0 7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 KNZ80836.1 - 0.0078 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Cutinase Peptidase_S9 PF00326.16 KNZ80836.1 - 0.029 13.5 0.0 0.17 11.0 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF1749 PF08538.5 KNZ80836.1 - 0.042 12.7 0.0 2.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) PGAP1 PF07819.8 KNZ80836.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein RVP_2 PF08284.6 KNZ80837.1 - 0.19 11.6 0.9 0.59 10.0 0.2 2.0 1 1 0 2 2 2 0 Retroviral aspartyl protease Abhydrolase_6 PF12697.2 KNZ80838.1 - 8.8e-14 51.9 0.1 2e-13 50.7 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ80838.1 - 4.8e-10 39.3 0.0 6.5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KNZ80838.1 - 2.1e-05 24.1 0.0 3.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 KNZ80838.1 - 0.00063 19.5 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Cutinase PGAP1 PF07819.8 KNZ80838.1 - 0.0014 18.2 0.0 0.002 17.7 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein DUF1749 PF08538.5 KNZ80838.1 - 0.039 12.8 0.0 2.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.15 KNZ80838.1 - 0.06 12.8 0.0 0.094 12.2 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 KNZ80838.1 - 0.088 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 KNZ80838.1 - 0.13 11.4 0.0 0.51 9.5 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family p450 PF00067.17 KNZ80839.1 - 5e-64 216.5 0.0 6.4e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Chol_subst-bind PF09129.6 KNZ80840.1 - 0.13 11.3 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding p450 PF00067.17 KNZ80841.1 - 3.5e-49 167.5 0.0 8.8e-47 159.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KNZ80842.1 - 1.3e-09 37.2 6.2 1.4e-09 37.1 4.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KNZ80842.1 - 0.041 12.2 2.4 0.047 12.0 1.7 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein p450 PF00067.17 KNZ80843.1 - 6.5e-32 110.6 0.0 1e-17 63.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Tannase PF07519.6 KNZ80844.1 - 2.1e-97 326.8 0.0 3e-68 230.6 0.0 2.0 1 1 1 2 2 2 2 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KNZ80844.1 - 2.6e-05 24.2 0.0 6.4e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ80844.1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ80844.1 - 0.00062 19.5 0.0 0.016 14.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ80844.1 - 0.075 12.2 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase3_N PF03893.11 KNZ80845.1 - 0.092 12.5 0.4 2.8 7.8 0.2 2.1 2 0 0 2 2 2 0 Lipase 3 N-terminal region Rad60-SLD PF11976.3 KNZ80847.1 - 4e-24 84.0 0.2 5.2e-24 83.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KNZ80847.1 - 4.3e-10 38.8 0.1 6e-10 38.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family MatE PF01554.13 KNZ80848.1 - 5.9e-22 78.0 2.8 5.9e-22 78.0 1.9 2.3 2 1 0 2 2 2 1 MatE MCP_N PF05581.7 KNZ80849.1 - 0.077 13.1 0.2 6.8 6.9 0.0 3.4 3 0 0 3 3 3 0 Vibrio chemotaxis protein N terminus TPR_12 PF13424.1 KNZ80850.1 - 1.6e-15 56.8 3.1 0.00013 21.8 0.0 5.1 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ80850.1 - 2.6e-09 37.4 9.8 0.0032 18.1 0.4 5.1 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ80850.1 - 3.2e-08 32.8 15.2 0.08 12.9 0.1 6.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ80850.1 - 8.5e-07 29.2 3.2 0.65 10.3 0.0 4.8 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ80850.1 - 2.6e-06 26.7 10.1 0.018 14.7 0.2 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ80850.1 - 5.6e-06 25.9 3.0 2.7 7.7 0.1 5.3 5 1 1 6 6 6 2 TPR repeat TPR_7 PF13176.1 KNZ80850.1 - 0.00022 20.7 0.2 11 6.1 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ80850.1 - 0.0032 17.9 16.4 10 7.0 0.0 7.8 6 2 3 9 9 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ80850.1 - 0.0052 16.3 6.7 2.1 8.0 0.2 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 KNZ80850.1 - 0.035 14.0 5.1 16 5.6 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 KNZ80850.1 - 0.045 13.6 2.8 1 9.2 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Cohesin_load PF10345.4 KNZ80850.1 - 0.088 11.0 0.0 2.7 6.0 0.0 2.5 1 1 1 2 2 2 0 Cohesin loading factor TPR_6 PF13174.1 KNZ80850.1 - 0.1 13.0 8.0 9.3 6.9 0.0 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat Tcf25 PF04910.9 KNZ80850.1 - 0.13 11.1 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Transcriptional repressor TCF25 PRK PF00485.13 KNZ80851.1 - 0.087 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CHB_HEX_C_1 PF13290.1 KNZ80851.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain Phage_integrase PF00589.17 KNZ80852.1 - 4e-06 26.6 0.0 6.4e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.12 KNZ80852.1 - 0.038 14.1 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain RHD3 PF05879.7 KNZ80853.1 - 5.4e-251 834.6 6.5 6.8e-250 831.0 4.5 1.9 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KNZ80853.1 - 5.6e-07 28.8 0.2 1.4e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KNZ80853.1 - 1.7e-05 24.7 0.0 3.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KNZ80853.1 - 1.9e-05 24.5 0.0 4.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KNZ80853.1 - 4e-05 24.1 0.1 9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 KNZ80853.1 - 0.0012 18.8 0.1 0.0033 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain Septin PF00735.13 KNZ80853.1 - 0.054 12.5 0.1 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 Septin AMP-binding PF00501.23 KNZ80854.1 - 1e-35 122.9 0.0 1.5e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KNZ80854.1 - 0.00025 21.9 0.0 0.00046 21.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HlyIII PF03006.15 KNZ80856.1 - 3.1e-40 137.9 15.6 3.1e-40 137.9 10.8 1.4 2 0 0 2 2 2 1 Haemolysin-III related Pept_tRNA_hydro PF01195.14 KNZ80857.1 - 1.3e-32 112.8 0.0 1.5e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Glyco_hydro_92 PF07971.7 KNZ80858.1 - 6.3e-122 407.7 0.7 8.1e-122 407.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 E2R135 PF11570.3 KNZ80858.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Macoilin PF09726.4 KNZ80859.1 - 0.04 12.2 11.4 0.05 11.8 7.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4391 PF14335.1 KNZ80861.1 - 0.0045 16.4 1.4 0.0067 15.8 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) Allexi_40kDa PF05549.6 KNZ80861.1 - 0.088 12.0 0.9 0.19 10.9 0.6 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein FpoO PF10621.4 KNZ80862.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO Pkinase PF00069.20 KNZ80863.1 - 9.4e-26 90.5 0.0 1.4e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ80863.1 - 5.5e-15 55.1 0.0 7.8e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ80863.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyoxal_oxid_N PF07250.6 KNZ80864.1 - 1.8e-41 141.8 0.2 7.4e-38 129.9 0.0 3.4 3 1 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KNZ80864.1 - 2.8e-21 75.4 0.1 4.9e-21 74.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 KNZ80864.1 - 0.00066 19.4 1.1 1.2 8.9 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Asp_protease_2 PF13650.1 KNZ80866.1 - 0.0071 16.8 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ80866.1 - 0.02 14.4 0.2 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease SPT2 PF08243.6 KNZ80867.1 - 0.28 11.4 7.7 0.59 10.4 5.3 1.5 1 0 0 1 1 1 0 SPT2 chromatin protein Asp_protease_2 PF13650.1 KNZ80871.1 - 0.0027 18.1 0.0 0.003 18.0 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease Ribosomal_L12 PF00542.14 KNZ80872.1 - 0.22 11.5 2.9 0.48 10.4 2.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain APG6 PF04111.7 KNZ80872.1 - 0.29 10.1 2.2 0.37 9.7 1.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 NST1 PF13945.1 KNZ80873.1 - 7.2 6.6 15.6 0.077 13.0 3.8 2.7 3 0 0 3 3 3 0 Salt tolerance down-regulator VanZ PF04892.7 KNZ80874.1 - 5.9e-08 32.7 3.8 2e-07 31.0 2.7 1.8 1 1 0 1 1 1 1 VanZ like family DUF2339 PF10101.4 KNZ80874.1 - 0.057 11.6 0.5 0.069 11.4 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) TauE PF01925.14 KNZ80874.1 - 0.067 12.6 0.2 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE YjgP_YjgQ PF03739.9 KNZ80874.1 - 0.092 11.4 1.1 0.13 10.9 0.8 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Caa3_CtaG PF09678.5 KNZ80874.1 - 0.26 10.1 3.0 0.34 9.7 2.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) DUF1275 PF06912.6 KNZ80874.1 - 0.9 8.6 5.1 0.61 9.2 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) DUF2207 PF09972.4 KNZ80874.1 - 1.3 7.5 2.9 1.9 6.9 2.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TcpE PF12648.2 KNZ80874.1 - 2 8.6 5.5 1.6 8.8 2.4 1.8 1 1 1 2 2 2 0 TcpE family DUF1319 PF07028.6 KNZ80875.1 - 0.026 14.6 0.4 0.026 14.6 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1319) DUF641 PF04859.7 KNZ80875.1 - 0.037 13.7 1.5 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) MerR-DNA-bind PF09278.6 KNZ80875.1 - 0.045 14.1 2.9 0.063 13.6 0.5 2.3 2 0 0 2 2 2 0 MerR, DNA binding Ank_5 PF13857.1 KNZ80876.1 - 4.7e-12 45.7 0.6 2.4e-06 27.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KNZ80876.1 - 2.1e-11 43.0 0.1 8.7e-06 25.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KNZ80876.1 - 5.5e-11 42.6 0.0 1.1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 KNZ80876.1 - 1e-10 41.4 0.3 3.4e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 IPT/TIG domain Ank_4 PF13637.1 KNZ80876.1 - 1.7e-08 34.7 0.0 6.9e-06 26.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ80876.1 - 1.7e-05 24.6 0.1 0.077 13.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ran_BP1 PF00638.13 KNZ80877.1 - 2.3e-11 43.8 0.0 3.7e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 KNZ80877.1 - 0.0044 17.2 34.2 0.0044 17.2 23.7 3.8 2 1 1 3 3 3 1 Nucleoporin FG repeat region NUP50 PF08911.6 KNZ80877.1 - 0.046 14.0 1.0 0.046 14.0 0.7 5.4 6 3 0 6 6 6 0 NUP50 (Nucleoporin 50 kDa) RabGAP-TBC PF00566.13 KNZ80878.1 - 2.7e-50 170.8 0.1 3.8e-50 170.3 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.1 KNZ80878.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Interleukin 34 Methyltransf_6 PF03737.10 KNZ80879.1 - 5e-21 75.1 0.1 3.5e-20 72.4 0.0 2.1 2 1 0 2 2 2 1 Demethylmenaquinone methyltransferase IMS PF00817.15 KNZ80880.1 - 1.1e-40 138.8 0.0 2.1e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KNZ80880.1 - 2.1e-08 34.1 0.0 6.1e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KNZ80880.1 - 3.5e-06 26.7 0.0 9.4e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif RVP_2 PF08284.6 KNZ80881.1 - 0.0016 18.3 0.1 0.0019 18.1 0.1 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease TPR_MLP1_2 PF07926.7 KNZ80885.1 - 5.4 6.7 45.6 5.4 6.7 8.9 4.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF755 PF05501.6 KNZ80885.1 - 9.2 6.3 14.8 0.75 9.8 5.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Glyco_tran_28_C PF04101.11 KNZ80886.1 - 0.066 12.8 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Chromo_shadow PF01393.14 KNZ80888.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Chromo shadow domain UbiA PF01040.13 KNZ80889.1 - 2e-19 69.8 24.1 2.7e-19 69.4 16.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family PP-binding PF00550.20 KNZ80890.1 - 1.4e-16 60.4 5.6 1.2e-09 38.3 0.5 2.3 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 KNZ80891.1 - 5.7e-22 78.2 0.0 8.1e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Zip PF02535.17 KNZ80892.1 - 9.6e-30 103.6 10.2 1.2e-29 103.3 7.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter E1_dh PF00676.15 KNZ80893.1 - 1.5e-79 266.8 0.0 1.9e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Peptidase_C48 PF02902.14 KNZ80894.1 - 9.4e-26 90.7 0.0 3.7e-22 78.9 0.0 3.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SKN1 PF03935.10 KNZ80895.1 - 1e-202 673.7 1.7 1.3e-202 673.4 1.1 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) PIF1 PF05970.9 KNZ80896.1 - 1.9e-09 36.9 0.0 1.9e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase BESS PF02944.15 KNZ80897.1 - 0.0072 15.8 0.1 0.94 9.0 0.0 2.6 3 0 0 3 3 3 2 BESS motif Herpes_Helicase PF02689.9 KNZ80899.1 - 8.5e-06 23.8 0.0 9e-06 23.7 0.0 1.0 1 0 0 1 1 1 1 Helicase RRM_1 PF00076.17 KNZ80901.1 - 5.6e-54 179.6 1.7 6.8e-17 60.8 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ80901.1 - 2.5e-42 142.6 0.2 8.2e-12 44.9 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ80901.1 - 4.2e-22 77.7 0.2 3.7e-05 23.4 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KNZ80901.1 - 1.9e-06 27.5 0.0 0.25 11.1 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 KNZ80901.1 - 0.0041 16.8 0.0 0.71 9.6 0.0 3.4 1 1 1 2 2 2 1 Nup53/35/40-type RNA recognition motif TPR_11 PF13414.1 KNZ80901.1 - 0.011 15.3 0.1 0.49 10.0 0.2 2.8 2 0 0 2 2 2 0 TPR repeat U3_assoc_6 PF08640.6 KNZ80901.1 - 0.018 14.7 2.6 0.081 12.6 0.5 2.6 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 OB_RNB PF08206.6 KNZ80901.1 - 0.32 10.5 2.1 2.2 7.8 0.0 2.9 3 0 0 3 3 3 0 Ribonuclease B OB domain RNase_H PF00075.19 KNZ80902.1 - 0.00068 19.9 0.0 0.0022 18.3 0.0 1.9 1 0 0 1 1 1 1 RNase H DUF664 PF04978.7 KNZ80902.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF664) BTB PF00651.26 KNZ80903.1 - 0.0013 18.7 0.2 2.3 8.2 0.1 3.3 3 0 0 3 3 3 2 BTB/POZ domain Uricase PF01014.13 KNZ80903.1 - 0.0087 16.1 0.1 0.66 10.0 0.0 2.7 2 0 0 2 2 2 1 Uricase RhgB_N PF09284.5 KNZ80904.1 - 4.2e-83 278.5 2.0 6.5e-83 277.8 1.4 1.3 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 KNZ80904.1 - 1.6e-55 187.3 0.1 3.3e-55 186.2 0.1 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III GRASP55_65 PF04495.9 KNZ80905.1 - 2.2e-59 199.3 0.0 1.2e-41 141.9 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KNZ80905.1 - 0.00012 21.8 0.0 0.48 10.3 0.0 2.2 2 0 0 2 2 2 2 PDZ domain G6B PF15096.1 KNZ80905.1 - 0.035 13.6 0.1 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 G6B family Ank PF00023.25 KNZ80906.1 - 0.012 15.3 0.1 0.08 12.7 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.2 KNZ80906.1 - 0.013 15.8 0.0 0.046 14.0 0.0 2.1 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KNZ80906.1 - 0.031 14.4 0.0 0.77 10.1 0.0 3.2 2 0 0 2 2 2 0 Ankyrin repeat Thr_synth_N PF14821.1 KNZ80906.1 - 0.079 12.9 0.0 0.51 10.4 0.0 2.4 3 0 0 3 3 3 0 Threonine synthase N terminus Fungal_trans PF04082.13 KNZ80907.1 - 1.1e-21 76.8 0.0 1.8e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ80907.1 - 2.6e-08 33.6 10.7 5.4e-08 32.6 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ThiF PF00899.16 KNZ80908.1 - 3.1e-10 40.0 2.0 7e-10 38.8 0.2 2.4 2 1 0 2 2 2 1 ThiF family DUF2924 PF11149.3 KNZ80908.1 - 0.032 14.2 0.2 0.068 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) FAD_binding_2 PF00890.19 KNZ80909.1 - 2.8e-45 154.9 2.9 2.9e-39 135.1 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KNZ80909.1 - 7.1e-09 35.0 0.9 0.00037 19.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KNZ80909.1 - 9.3e-08 31.5 0.2 0.00027 20.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KNZ80909.1 - 4.5e-05 22.1 3.5 0.063 11.7 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 KNZ80909.1 - 0.00024 20.0 4.1 0.00083 18.3 0.3 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KNZ80909.1 - 0.00043 20.2 0.1 0.041 13.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNZ80909.1 - 0.00099 19.2 0.0 0.1 12.6 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ80909.1 - 0.0035 17.3 2.8 0.0039 17.1 0.5 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KNZ80909.1 - 0.06 12.3 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 KNZ80909.1 - 0.14 11.0 0.1 0.83 8.5 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein PLDc PF00614.17 KNZ80910.1 - 2e-12 46.5 0.5 4.2e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KNZ80910.1 - 2.5e-12 46.6 0.0 7.3e-07 28.9 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 KNZ80910.1 - 0.0016 18.1 0.6 0.0065 16.2 0.1 2.3 2 0 0 2 2 2 1 PX domain PH PF00169.24 KNZ80910.1 - 0.0025 18.0 0.0 0.0075 16.4 0.0 1.9 1 0 0 1 1 1 1 PH domain PROCN PF08083.6 KNZ80912.1 - 2.5e-219 727.7 8.7 6.7e-219 726.3 5.5 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KNZ80912.1 - 5.5e-127 421.7 0.5 9.8e-127 420.9 0.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KNZ80912.1 - 4.1e-83 276.5 1.2 4.1e-83 276.5 0.9 2.1 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KNZ80912.1 - 8.2e-80 265.7 2.3 8.2e-80 265.7 1.6 2.3 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KNZ80912.1 - 9.6e-65 216.2 0.1 2e-64 215.2 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 KNZ80912.1 - 3.7e-43 145.3 0.1 8.3e-43 144.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 KNZ80912.1 - 3.6e-31 107.4 0.0 1e-30 106.0 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 KNZ80912.1 - 2.4e-05 24.0 0.0 5.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PH PF00169.24 KNZ80913.1 - 0.00022 21.3 0.0 0.00055 20.1 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF837 PF05769.6 KNZ80916.1 - 4e-06 26.4 10.3 0.00044 19.8 4.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF837) NYD-SP28_assoc PF14775.1 KNZ80916.1 - 0.00032 20.3 8.3 0.023 14.3 1.6 2.9 2 0 0 2 2 2 2 Sperm tail C-terminal domain Herpes_BLRF2 PF05812.7 KNZ80916.1 - 0.0077 16.0 2.2 0.077 12.8 0.0 2.4 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein AIP3 PF03915.8 KNZ80916.1 - 0.027 13.3 5.6 0.037 12.9 3.9 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Nsp1_C PF05064.8 KNZ80916.1 - 0.037 13.6 0.9 0.037 13.6 0.6 2.3 2 1 0 2 2 2 0 Nsp1-like C-terminal region HALZ PF02183.13 KNZ80916.1 - 0.13 12.0 6.8 0.95 9.2 0.2 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF3698 PF12479.3 KNZ80916.1 - 0.24 11.5 2.4 14 5.8 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3698) Peptidase_S64 PF08192.6 KNZ80916.1 - 0.39 8.9 4.0 0.52 8.5 2.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 Cor1 PF04803.7 KNZ80916.1 - 0.47 10.2 8.1 1.2 8.9 3.9 2.3 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region DUF972 PF06156.8 KNZ80916.1 - 0.84 10.0 12.0 3 8.2 3.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) IFT20 PF14931.1 KNZ80916.1 - 1 9.2 11.2 2.6 7.9 1.0 3.2 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 DUF641 PF04859.7 KNZ80916.1 - 1.6 8.4 8.2 1.1 8.9 1.7 2.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) WXG100 PF06013.7 KNZ80916.1 - 2.3 8.2 6.2 7.6 6.6 0.5 3.4 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Asp_protease_2 PF13650.1 KNZ80918.1 - 8.2e-05 23.0 0.0 0.00013 22.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KNZ80918.1 - 8.6e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KNZ80918.1 - 0.0019 18.1 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Hydrophobin PF01185.13 KNZ80919.1 - 0.011 16.1 0.3 0.012 16.0 0.2 1.2 1 0 0 1 1 1 0 Fungal hydrophobin Ribosomal_S19e PF01090.14 KNZ80920.1 - 5.9e-56 187.7 0.0 6.8e-56 187.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HEAT_2 PF13646.1 KNZ80920.1 - 0.054 13.7 0.2 0.67 10.2 0.1 2.2 2 0 0 2 2 2 0 HEAT repeats F-box-like PF12937.2 KNZ80921.1 - 2.8e-10 39.7 0.0 6.6e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF4231 PF14015.1 KNZ80923.1 - 4.2 7.4 7.7 0.8 9.7 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Glyco_transf_28 PF03033.15 KNZ80924.1 - 6.9e-24 84.1 0.0 1.2e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 KNZ80924.1 - 8.5e-08 31.6 0.0 0.0023 17.4 0.0 2.6 2 0 0 2 2 2 2 GRAM domain UDPGT PF00201.13 KNZ80924.1 - 1.8e-06 26.8 0.0 3.7e-06 25.7 0.0 1.4 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase DAHP_synth_1 PF00793.15 KNZ80925.1 - 1.5e-90 302.6 0.0 1.8e-90 302.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family zf-Tim10_DDP PF02953.10 KNZ80926.1 - 7.9e-19 66.7 6.4 9.9e-19 66.4 4.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mmp37 PF09139.6 KNZ80926.1 - 0.037 13.0 0.1 0.038 13.0 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 DUF1178 PF06676.6 KNZ80926.1 - 0.066 13.4 0.2 0.33 11.1 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) QueF PF14489.1 KNZ80926.1 - 0.15 11.9 0.5 0.42 10.5 0.1 1.8 1 1 1 2 2 2 0 QueF-like protein AhpC-TSA PF00578.16 KNZ80927.1 - 2.6e-14 52.9 0.0 3e-12 46.3 0.0 2.2 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KNZ80927.1 - 6.2e-07 29.0 0.0 9.3e-06 25.2 0.0 2.1 1 1 0 1 1 1 1 Redoxin dsrm PF00035.20 KNZ80928.1 - 1.2e-13 51.4 0.1 2e-08 34.6 0.1 2.3 2 0 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KNZ80928.1 - 0.041 14.1 0.3 19 5.6 0.1 3.0 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 NMO PF03060.10 KNZ80929.1 - 3.3e-65 220.4 0.1 4.2e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KNZ80929.1 - 9.3e-11 41.1 0.1 1.1e-05 24.5 0.6 2.7 1 1 2 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KNZ80929.1 - 0.00097 18.0 0.5 0.0015 17.4 0.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TMP-TENI PF02581.12 KNZ80929.1 - 0.0014 17.7 0.0 0.003 16.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI His_biosynth PF00977.16 KNZ80929.1 - 0.012 14.9 0.1 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF1902 PF08972.6 KNZ80929.1 - 0.024 14.1 2.1 0.091 12.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1902) NanE PF04131.9 KNZ80929.1 - 0.033 13.1 0.2 0.069 12.1 0.0 1.6 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.12 KNZ80929.1 - 0.057 12.3 0.2 0.11 11.3 0.1 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.16 KNZ80929.1 - 0.12 11.2 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Pkinase PF00069.20 KNZ80930.1 - 2.2e-51 174.5 0.0 3.9e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ80930.1 - 1.9e-22 79.6 0.0 3.2e-21 75.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ80930.1 - 0.0022 17.0 0.0 0.0058 15.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KNZ80930.1 - 0.017 14.4 0.3 0.017 14.4 0.2 2.3 3 0 0 3 3 3 0 RIO1 family APH PF01636.18 KNZ80930.1 - 0.048 13.3 0.0 0.95 9.1 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ80931.1 - 7.8e-19 67.8 0.0 5.5e-17 61.7 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ80931.1 - 1.9e-12 46.8 0.0 3.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ80931.1 - 5e-05 22.3 0.0 9.2e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ80931.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family hDGE_amylase PF14701.1 KNZ80931.1 - 0.03 13.2 0.0 2.2 7.1 0.0 2.2 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme Exo_endo_phos PF03372.18 KNZ80932.1 - 1.8e-12 47.7 0.7 3.5e-12 46.7 0.5 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ADAM_spacer1 PF05986.9 KNZ80932.1 - 0.04 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 ADAM-TS Spacer 1 Exo_endo_phos PF03372.18 KNZ80933.1 - 1.5e-10 41.4 0.4 2.7e-10 40.6 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KNZ80933.1 - 0.04 13.5 0.3 0.2 11.2 0.1 2.3 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase DUF2353 PF09789.4 KNZ80934.1 - 0.0047 16.2 0.3 0.006 15.8 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Reo_sigmaC PF04582.7 KNZ80934.1 - 0.022 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein SH3BP5 PF05276.9 KNZ80934.1 - 0.025 13.9 0.9 0.036 13.3 0.7 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Transcrip_act PF04949.8 KNZ80934.1 - 0.027 14.1 0.1 0.057 13.0 0.1 1.5 1 1 1 2 2 2 0 Transcriptional activator BLOC1_2 PF10046.4 KNZ80934.1 - 0.029 14.5 1.0 0.087 12.9 0.5 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CHASE3 PF05227.8 KNZ80934.1 - 0.09 12.4 3.0 0.11 12.1 1.2 1.8 1 1 0 2 2 2 0 CHASE3 domain Spc7 PF08317.6 KNZ80934.1 - 0.093 11.3 0.7 0.12 10.9 0.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CCDC92 PF14916.1 KNZ80934.1 - 0.13 11.9 0.1 0.32 10.6 0.0 1.7 1 1 1 2 2 2 0 Coiled-coil domain of unknown function NPV_P10 PF05531.7 KNZ80934.1 - 0.29 11.4 2.6 1.2 9.4 0.4 2.3 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein POP1 PF06978.6 KNZ80935.1 - 2.1e-49 167.7 15.1 1.2e-27 96.8 2.6 2.5 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KNZ80935.1 - 7.4e-29 99.4 0.1 1.8e-28 98.2 0.1 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.16 KNZ80935.1 - 9.6e-07 28.3 0.0 0.037 13.3 0.0 2.5 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain DUF3649 PF12365.3 KNZ80935.1 - 8.2 6.0 7.4 4.3 6.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) Nbl1_Borealin_N PF10444.4 KNZ80936.1 - 2.2e-09 36.5 0.2 4.1e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal 3Beta_HSD PF01073.14 KNZ80937.1 - 5.2e-66 222.2 0.0 7.9e-66 221.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KNZ80937.1 - 4.4e-37 127.7 0.0 5.9e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ80937.1 - 9.2e-20 71.4 0.2 1.3e-19 70.8 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KNZ80937.1 - 5.4e-17 61.6 0.0 7.4e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KNZ80937.1 - 7.5e-14 51.2 0.0 5.9e-10 38.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 KNZ80937.1 - 9.9e-07 27.9 1.8 1.3e-05 24.2 1.2 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KNZ80937.1 - 4.4e-05 22.8 0.4 0.00029 20.1 0.3 2.0 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KNZ80937.1 - 9.1e-05 22.4 2.6 0.0016 18.4 1.8 2.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ80937.1 - 0.00077 19.1 0.7 0.0068 16.0 0.4 2.2 1 1 0 1 1 1 1 KR domain DUF1537 PF07005.6 KNZ80937.1 - 0.0064 16.1 0.1 0.019 14.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF1537 D123 PF07065.9 KNZ80938.1 - 8.2e-78 261.4 0.1 9.6e-78 261.2 0.1 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 KNZ80938.1 - 0.027 14.3 0.1 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) CENP-B_dimeris PF09026.5 KNZ80938.1 - 0.047 13.9 5.0 0.082 13.1 3.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FA_desaturase PF00487.19 KNZ80939.1 - 4.1e-24 85.4 21.1 8.8e-24 84.3 14.6 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KNZ80939.1 - 0.063 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) DUF3374 PF11854.3 KNZ80939.1 - 0.12 10.5 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3374) Pkinase PF00069.20 KNZ80940.1 - 4.4e-18 65.3 0.0 7.3e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ80940.1 - 0.012 14.6 0.0 0.13 11.2 0.0 2.3 3 0 0 3 3 3 0 Protein tyrosine kinase APH PF01636.18 KNZ80940.1 - 0.014 15.1 0.1 0.063 12.9 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family TPP_enzyme_N PF02776.13 KNZ80941.1 - 3e-33 114.7 0.0 7.1e-33 113.5 0.0 1.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KNZ80941.1 - 1.8e-18 66.6 0.0 3.2e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KNZ80941.1 - 1.7e-11 43.9 0.0 5.6e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 KNZ80942.1 - 9.5e-38 129.3 0.0 1.4e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KNZ80942.1 - 3.1e-22 78.7 0.0 6.5e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KNZ80942.1 - 3.3e-11 42.9 0.0 6.4e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Peptidase_M3 PF01432.15 KNZ80943.1 - 2.5e-133 445.4 0.0 3.3e-133 445.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 KNZ80943.1 - 0.044 13.1 0.2 0.072 12.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like TPP_enzyme_N PF02776.13 KNZ80944.1 - 1.2e-27 96.4 0.1 6.1e-26 90.9 0.1 2.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KNZ80944.1 - 1.8e-18 66.5 0.0 3.3e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KNZ80944.1 - 1.7e-11 43.9 0.0 5.4e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Usp PF00582.21 KNZ80945.1 - 1e-21 77.6 0.1 1e-21 77.6 0.1 2.2 2 0 0 2 2 2 1 Universal stress protein family Acetyltransf_CG PF14542.1 KNZ80945.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pet127 PF08634.5 KNZ80946.1 - 4.6e-99 331.0 0.0 6e-99 330.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Arf PF00025.16 KNZ80947.1 - 9.2e-38 129.2 0.0 1.2e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KNZ80947.1 - 1e-19 70.5 0.0 1.2e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ80947.1 - 2.7e-12 47.2 0.0 4.5e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KNZ80947.1 - 2e-09 36.9 0.0 2.5e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KNZ80947.1 - 2.3e-07 30.1 0.0 2.4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KNZ80947.1 - 3.8e-06 26.8 0.0 5.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KNZ80947.1 - 3.8e-05 22.5 0.3 8e-05 21.4 0.1 1.4 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.18 KNZ80947.1 - 0.00017 21.4 0.2 0.049 13.4 0.3 2.2 1 1 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 KNZ80947.1 - 0.0004 19.8 0.0 0.0034 16.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KNZ80947.1 - 0.0017 17.9 0.2 0.39 10.2 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein DSBA PF01323.15 KNZ80947.1 - 0.068 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain DUF2205 PF10224.4 KNZ80948.1 - 2.1e-13 49.6 0.4 2.6e-13 49.3 0.3 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) AAA_27 PF13514.1 KNZ80948.1 - 0.017 12.8 0.1 0.018 12.7 0.1 1.0 1 0 0 1 1 1 0 AAA domain DivIC PF04977.10 KNZ80948.1 - 0.018 14.5 0.2 0.023 14.1 0.2 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 KNZ80948.1 - 0.02 15.2 1.0 0.022 15.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3450 PF11932.3 KNZ80948.1 - 0.024 13.9 0.2 0.024 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RPW8 PF05659.6 KNZ80948.1 - 0.036 13.6 0.1 0.046 13.2 0.0 1.0 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF496 PF04363.7 KNZ80948.1 - 0.064 13.0 0.3 0.073 12.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF496) DUF2299 PF10061.4 KNZ80948.1 - 0.11 11.9 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) TMF_DNA_bd PF12329.3 KNZ80948.1 - 0.11 12.3 0.7 0.14 11.9 0.5 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Proteasom_Rpn13 PF04683.8 KNZ80949.1 - 3e-24 84.9 0.0 4.6e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor zf-Nse PF11789.3 KNZ80951.1 - 7.5e-15 54.1 0.1 1.4e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KNZ80951.1 - 0.00068 19.3 0.2 0.0017 18.0 0.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.10 KNZ80951.1 - 0.015 15.2 0.1 0.057 13.3 0.0 2.1 2 0 0 2 2 2 0 U-box domain zf-C3HC4_2 PF13923.1 KNZ80951.1 - 0.023 14.7 0.2 0.037 14.0 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ80951.1 - 0.027 14.1 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pox_H7 PF04787.7 KNZ80951.1 - 0.28 10.9 2.3 0.23 11.2 0.2 1.8 2 0 0 2 2 2 0 Late protein H7 Ribosom_S12_S23 PF00164.20 KNZ80952.1 - 1.8e-42 143.5 2.0 4.2e-42 142.4 1.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S12/S23 PH_4 PF15404.1 KNZ80953.1 - 2.3e-26 92.4 0.1 7.2e-25 87.5 0.0 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain AOX PF01786.12 KNZ80954.1 - 5.5e-79 264.3 0.3 7.2e-79 263.9 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase Tn7_TnsC_Int PF11426.3 KNZ80954.1 - 0.064 12.9 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC Fungal_trans PF04082.13 KNZ80955.1 - 1.1e-07 30.9 0.1 2.1e-07 30.1 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ80955.1 - 1.9e-06 27.6 5.9 3.2e-06 26.9 4.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tom22 PF04281.8 KNZ80956.1 - 3.3e-40 136.7 2.2 3.9e-40 136.5 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 NAD_binding_10 PF13460.1 KNZ80957.1 - 1e-18 68.0 0.0 1.5e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KNZ80957.1 - 1.1e-12 47.7 0.0 1.5e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KNZ80957.1 - 8.1e-11 41.8 0.0 2.6e-09 36.8 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KNZ80957.1 - 1.9e-10 40.1 0.0 1.5e-08 33.8 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KNZ80957.1 - 7.4e-10 37.9 0.0 1.3e-09 37.2 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KNZ80957.1 - 1.6e-08 33.7 0.3 5.5e-05 22.2 0.2 3.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KNZ80957.1 - 0.0017 17.3 0.1 0.0031 16.4 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KNZ80957.1 - 0.0076 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF2462 PF09495.5 KNZ80958.1 - 2.8e-17 63.2 10.0 3e-17 63.1 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Sas10 PF09368.5 KNZ80960.1 - 1.6e-23 82.6 1.9 1.6e-23 82.6 1.3 3.5 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KNZ80960.1 - 1e-05 25.6 0.4 4.1e-05 23.6 0.2 2.1 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Fcf2 PF08698.6 KNZ80961.1 - 3.2e-19 68.7 0.0 6.4e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Rgp1 PF08737.5 KNZ80961.1 - 0.069 12.2 0.3 0.092 11.8 0.2 1.2 1 0 0 1 1 1 0 Rgp1 Cwf_Cwc_15 PF04889.7 KNZ80961.1 - 1.4 8.5 6.5 0.38 10.4 0.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ubie_methyltran PF01209.13 KNZ80962.1 - 2.8e-77 258.9 0.0 3.5e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KNZ80962.1 - 8.6e-15 54.6 0.0 1.7e-14 53.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ80962.1 - 3.3e-13 49.9 0.0 5.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ80962.1 - 4.6e-12 46.1 0.0 7.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ80962.1 - 1.7e-10 40.8 0.0 2.7e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ80962.1 - 6.4e-10 39.4 0.0 9.8e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ80962.1 - 1.3e-07 32.2 0.0 2.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ80962.1 - 0.00044 20.2 0.0 0.0011 18.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 KNZ80962.1 - 0.025 13.9 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.1 KNZ80962.1 - 0.068 12.8 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Tautomerase PF01361.16 KNZ80962.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme Cullin PF00888.17 KNZ80963.1 - 3.4e-161 537.7 18.0 4.4e-161 537.3 12.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KNZ80963.1 - 1.3e-20 72.9 2.8 2.6e-20 71.9 0.8 2.5 3 0 0 3 3 3 1 Cullin protein neddylation domain Rrf2 PF02082.15 KNZ80963.1 - 0.029 14.4 0.2 0.15 12.2 0.0 2.3 3 0 0 3 3 3 0 Transcriptional regulator GST_N_3 PF13417.1 KNZ80966.1 - 7.3e-11 42.1 0.0 1.3e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KNZ80966.1 - 1.4e-10 41.2 0.0 3.7e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KNZ80966.1 - 2.2e-08 33.9 0.0 4.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KNZ80966.1 - 5.6e-05 22.9 0.0 0.00015 21.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KNZ80966.1 - 0.0016 18.4 0.0 0.0085 16.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain MRP-L20 PF12824.2 KNZ80967.1 - 2.9e-23 82.6 7.6 1e-22 80.8 5.3 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Malic_M PF03949.10 KNZ80968.1 - 1.2e-83 280.6 0.0 1.6e-83 280.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KNZ80968.1 - 3.8e-60 202.5 0.0 5.7e-60 202.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain SET PF00856.23 KNZ80969.1 - 1.5e-09 38.3 0.0 2.3e-07 31.2 0.0 2.5 1 1 0 1 1 1 1 SET domain dCMP_cyt_deam_1 PF00383.17 KNZ80969.1 - 5.3e-09 35.6 0.0 1.4e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Glycos_transf_4 PF00953.16 KNZ80970.1 - 3.4e-31 108.1 8.0 3.4e-31 108.1 5.5 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 4 ICL PF00463.16 KNZ80971.1 - 2.6e-255 847.6 1.8 2.9e-255 847.4 1.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KNZ80971.1 - 4.1e-09 36.0 0.2 9.4e-09 34.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase PT-TG PF14449.1 KNZ80971.1 - 0.048 13.4 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Pre-toxin TG F-actin_cap_A PF01267.12 KNZ80972.1 - 1.5e-84 283.2 0.0 1.7e-84 283.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit RGS PF00615.14 KNZ80974.1 - 0.00023 21.2 0.2 0.011 15.8 0.1 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain VIT1 PF01988.14 KNZ80974.1 - 0.12 11.9 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 VIT family UPF0233 PF06781.7 KNZ80974.1 - 0.42 10.2 4.6 0.18 11.4 0.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Tcp11 PF05794.8 KNZ80976.1 - 4e-42 144.4 0.0 4.9e-39 134.2 0.0 3.7 2 1 0 2 2 2 2 T-complex protein 11 SCRL PF06876.7 KNZ80976.1 - 0.045 13.7 2.0 0.09 12.7 1.4 1.4 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein ATP-synt_ab PF00006.20 KNZ80977.1 - 6.7e-62 208.7 0.0 8.9e-62 208.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KNZ80977.1 - 3.5e-17 62.8 0.0 7.8e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KNZ80977.1 - 1.1e-08 35.1 0.1 2.3e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KNZ80977.1 - 0.0072 16.2 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 HAS barrel domain TFCD_C PF12612.3 KNZ80978.1 - 1.4e-35 122.4 0.1 6.8e-34 116.9 0.0 3.6 3 1 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 KNZ80978.1 - 0.00032 20.5 2.6 0.12 12.5 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 KNZ80978.1 - 0.0013 18.9 0.2 3.7 7.8 0.0 4.4 4 1 0 4 4 4 1 HEAT repeats Cnd1 PF12717.2 KNZ80978.1 - 0.003 17.4 0.1 0.45 10.3 0.0 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KNZ80978.1 - 0.0058 17.0 3.1 15 6.2 0.0 5.2 5 0 0 5 5 5 1 HEAT-like repeat BUD22 PF09073.5 KNZ80979.1 - 1.6e-50 172.4 19.9 2.2e-50 172.0 13.8 1.1 1 0 0 1 1 1 1 BUD22 Sugar_tr PF00083.19 KNZ80980.1 - 1e-80 271.5 22.5 1.3e-80 271.2 15.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter PP2C PF00481.16 KNZ80980.1 - 4.3e-79 265.5 0.0 6e-79 265.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C MFS_1 PF07690.11 KNZ80980.1 - 5.2e-27 94.4 25.0 5.2e-27 94.4 17.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KNZ80980.1 - 8.7e-07 27.5 0.9 8.7e-07 27.5 0.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) CS PF04969.11 KNZ80981.1 - 2.6e-10 40.7 0.1 6.6e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 CS domain Asp_protease_2 PF13650.1 KNZ80984.1 - 0.077 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.1 KNZ80987.1 - 0.0079 16.6 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ80987.1 - 0.028 13.9 0.1 0.56 9.7 0.0 2.1 1 1 1 2 2 2 0 Aspartyl protease Trp_halogenase PF04820.9 KNZ80988.1 - 1.7e-26 92.8 0.4 1.4e-13 50.2 0.0 3.4 2 2 0 2 2 2 2 Tryptophan halogenase DAO PF01266.19 KNZ80988.1 - 1e-08 34.5 0.0 3e-05 23.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KNZ80988.1 - 1e-07 31.3 0.0 1.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KNZ80988.1 - 1.2e-05 25.2 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ80988.1 - 2.8e-05 24.0 0.8 7.3e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KNZ80988.1 - 3.7e-05 22.7 0.0 4.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KNZ80988.1 - 3.7e-05 22.9 0.4 7.5e-05 21.9 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KNZ80988.1 - 7.9e-05 21.2 0.0 0.00013 20.5 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KNZ80988.1 - 0.00031 21.0 0.0 0.0039 17.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KNZ80988.1 - 0.00037 19.4 0.5 0.00066 18.6 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KNZ80988.1 - 0.027 13.5 0.0 0.078 12.0 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 KNZ80988.1 - 0.057 12.3 0.1 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.16 KNZ80988.1 - 0.11 12.3 0.2 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.1 KNZ80988.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 KNZ80988.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KNZ80988.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase LCAT PF02450.10 KNZ80989.1 - 2.7e-50 171.4 1.0 5.5e-34 117.7 0.1 3.1 3 0 0 3 3 3 3 Lecithin:cholesterol acyltransferase UBN2_2 PF14227.1 KNZ80990.1 - 0.00026 20.5 0.3 0.4 10.2 0.1 2.2 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type zf-RVT PF13966.1 KNZ80992.1 - 0.024 14.9 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase NACHT PF05729.7 KNZ80994.1 - 5.4e-11 42.4 0.0 1.2e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 KNZ80994.1 - 8.9e-05 22.2 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 KNZ80994.1 - 0.00014 22.0 0.0 0.0081 16.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 KNZ80994.1 - 0.00016 21.6 0.0 0.00052 20.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KNZ80994.1 - 0.0003 20.9 0.0 0.00066 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KNZ80994.1 - 0.0034 17.5 0.0 0.01 16.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KNZ80994.1 - 0.0043 16.4 0.0 0.017 14.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 KNZ80994.1 - 0.0052 15.6 0.0 0.0084 15.0 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.12 KNZ80994.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.17 KNZ80994.1 - 0.25 10.1 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.21 KNZ80994.1 - 0.33 10.3 0.0 0.57 9.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Ank_2 PF12796.2 KNZ80995.1 - 2.8e-29 101.2 0.9 3.4e-16 59.3 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNZ80995.1 - 3.3e-21 75.2 0.1 7.6e-08 32.6 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KNZ80995.1 - 1.5e-19 69.5 1.1 8e-11 41.8 0.1 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KNZ80995.1 - 4.1e-19 67.3 0.3 5.4e-07 29.1 0.1 5.1 4 1 1 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 KNZ80995.1 - 8.7e-15 53.3 0.0 4e-05 23.4 0.0 4.5 4 1 1 5 5 5 2 Ankyrin repeat HHH_7 PF14635.1 KNZ80995.1 - 0.012 15.7 0.0 0.39 10.8 0.0 2.1 1 1 1 2 2 2 0 Helix-hairpin-helix motif DUF1858 PF08984.6 KNZ80995.1 - 0.057 13.0 0.1 0.35 10.5 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1858) EIIA-man PF03610.11 KNZ80995.1 - 0.092 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 PTS system fructose IIA component Herpes_Helicase PF02689.9 KNZ80996.1 - 1.8e-06 26.0 0.1 1.9e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ80996.1 - 0.09 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.9 KNZ80997.1 - 8.8e-39 133.4 0.2 1.2e-38 133.0 0.2 1.1 1 0 0 1 1 1 1 PIF1-like helicase Viral_helicase1 PF01443.13 KNZ80997.1 - 0.066 12.7 0.1 0.097 12.1 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KNZ80997.1 - 0.083 12.8 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 KNZ80997.1 - 0.096 12.2 0.2 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KNZ80997.1 - 0.11 12.6 0.1 0.28 11.3 0.0 1.7 2 0 0 2 2 2 0 RNA helicase F-box-like PF12937.2 KNZ80998.1 - 2.4e-05 23.9 0.5 5.7e-05 22.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like Chromo PF00385.19 KNZ81000.1 - 1.2e-07 31.2 0.5 2.2e-07 30.4 0.3 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain UBN2_2 PF14227.1 KNZ81001.1 - 9.8e-07 28.3 0.6 1.4e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ81001.1 - 0.0001 22.0 0.2 0.00016 21.4 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KNZ81001.1 - 0.01 15.3 0.1 0.092 12.3 0.1 2.3 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type TRI5 PF06330.6 KNZ81002.1 - 2.7e-17 62.4 0.1 3.7e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) PDEase_II PF02112.10 KNZ81002.1 - 0.0034 16.3 0.3 0.0058 15.6 0.2 1.3 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Sec61_beta PF03911.11 KNZ81003.1 - 1.4e-10 40.7 4.7 1.4e-05 24.7 2.1 2.3 2 0 0 2 2 2 2 Sec61beta family zf-RING_2 PF13639.1 KNZ81004.1 - 3.9e-07 29.7 4.9 3.9e-07 29.7 3.4 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KNZ81004.1 - 1.8e-06 27.4 5.0 1.8e-06 27.4 3.5 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ81004.1 - 2.4e-05 24.2 5.5 2.4e-05 24.2 3.8 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ81004.1 - 9.6e-05 22.0 5.4 9.6e-05 22.0 3.8 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KNZ81004.1 - 0.00057 19.5 0.1 0.00057 19.5 0.1 2.5 2 1 1 3 3 3 1 RING-type zinc-finger FYVE PF01363.16 KNZ81004.1 - 0.0014 18.5 2.7 0.0073 16.1 1.7 2.4 1 1 1 2 2 2 1 FYVE zinc finger zf-C3HC4_4 PF15227.1 KNZ81004.1 - 0.0016 18.2 5.9 0.0063 16.3 4.1 2.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C2H2_4 PF13894.1 KNZ81004.1 - 2.7 8.5 11.6 0.12 12.7 0.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Synaptobrevin PF00957.16 KNZ81005.1 - 4e-25 87.2 1.1 4.5e-25 87.0 0.8 1.0 1 0 0 1 1 1 1 Synaptobrevin GMC_oxred_N PF00732.14 KNZ81006.1 - 9.9e-17 61.0 0.0 5e-16 58.7 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ81006.1 - 2.5e-10 40.7 0.1 5.7e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KNZ81006.1 - 8.7e-09 34.7 0.0 1.2e-05 24.3 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ81006.1 - 5.1e-07 28.8 0.0 5.6e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KNZ81006.1 - 2.2e-05 24.3 0.3 7.1e-05 22.7 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KNZ81006.1 - 0.00014 21.0 0.0 0.0016 17.5 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KNZ81006.1 - 0.00015 20.9 0.1 0.00025 20.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KNZ81006.1 - 0.0002 19.9 0.0 0.00029 19.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KNZ81006.1 - 0.0017 18.2 0.1 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNZ81006.1 - 0.0018 18.3 0.0 0.011 15.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KNZ81006.1 - 0.0083 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KNZ81006.1 - 0.13 11.1 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Acyltransferase PF01553.16 KNZ81007.1 - 2.8e-14 52.6 0.0 4.6e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase TPR_11 PF13414.1 KNZ81008.1 - 1.1e-25 88.9 9.1 3.7e-12 45.7 0.3 5.8 5 1 1 6 6 6 5 TPR repeat TPR_1 PF00515.23 KNZ81008.1 - 1.3e-13 49.9 11.0 0.036 13.6 0.0 9.3 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ81008.1 - 2.8e-13 48.9 1.4 0.04 14.1 0.0 6.5 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ81008.1 - 2.4e-11 42.6 13.1 0.012 15.4 0.0 9.6 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ81008.1 - 4.3e-08 33.1 5.6 0.24 12.1 0.0 7.4 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ81008.1 - 2.9e-07 29.7 3.5 0.13 12.0 0.0 6.6 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ81008.1 - 3.9e-07 30.5 2.1 0.0011 19.6 0.0 4.6 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ81008.1 - 9.6e-07 29.0 5.2 0.15 12.4 0.0 6.3 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ81008.1 - 1.3e-06 28.2 13.0 0.0018 18.1 0.1 6.1 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ81008.1 - 0.00069 19.4 1.5 3.2 7.6 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ81008.1 - 0.00074 19.1 1.6 0.069 12.9 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat NYD-SP12_N PF15015.1 KNZ81008.1 - 0.0093 14.2 0.0 0.019 13.1 0.0 1.5 1 1 0 1 1 1 1 Spermatogenesis-associated, N-terminal SHNi-TPR PF10516.4 KNZ81008.1 - 0.096 11.9 0.3 7.2 5.9 0.0 3.2 3 0 0 3 3 3 0 SHNi-TPR Ribosomal_S11 PF00411.14 KNZ81009.1 - 8.2e-41 138.6 0.5 1e-40 138.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 zf-RING_2 PF13639.1 KNZ81010.1 - 0.00041 20.1 14.7 0.00041 20.1 10.2 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KNZ81010.1 - 0.00066 19.3 13.8 0.0015 18.1 9.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KNZ81010.1 - 0.00071 19.5 15.6 0.0014 18.5 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KNZ81010.1 - 0.0026 17.3 14.7 0.0054 16.3 10.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KNZ81010.1 - 0.026 14.2 9.1 0.1 12.3 6.3 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KNZ81010.1 - 0.2 11.5 15.4 0.4 10.5 10.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PAT1 PF09770.4 KNZ81010.1 - 0.2 9.8 14.0 0.26 9.5 9.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Baculo_IE-1 PF05290.6 KNZ81010.1 - 4.3 7.0 8.7 9.9 5.8 6.0 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 KNZ81010.1 - 8 6.1 17.0 0.32 10.6 7.6 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Glyco_hydro_65N PF03636.10 KNZ81012.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain ABC_tran PF00005.22 KNZ81013.1 - 1e-40 139.2 0.0 1.6e-20 73.7 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KNZ81013.1 - 2.4e-40 138.6 35.0 1.6e-22 80.2 6.9 3.1 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KNZ81013.1 - 3.5e-08 32.9 0.1 0.0021 17.3 0.0 3.0 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KNZ81013.1 - 0.0018 18.2 0.1 0.0072 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KNZ81013.1 - 0.0037 16.6 0.0 0.0086 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 KNZ81013.1 - 0.0055 16.6 0.0 2.9 7.8 0.0 3.7 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 KNZ81013.1 - 0.008 16.0 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 Dynamin family AAA_21 PF13304.1 KNZ81013.1 - 0.013 15.5 0.0 2.8 7.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 KNZ81013.1 - 0.069 12.8 0.2 0.31 10.7 0.0 2.2 3 0 0 3 3 3 0 Archaeal ATPase AAA_29 PF13555.1 KNZ81013.1 - 0.098 12.1 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 KNZ81013.1 - 0.2 11.2 0.5 2.5 7.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain Glyoxalase_4 PF13669.1 KNZ81015.1 - 0.024 14.6 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Beach PF02138.13 KNZ81018.1 - 3.5e-94 315.2 0.0 6.6e-94 314.3 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 KNZ81018.1 - 7.9e-11 41.4 6.9 0.0012 18.6 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat PH_BEACH PF14844.1 KNZ81018.1 - 3e-08 33.4 0.0 6.8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 KNZ81018.1 - 3.2e-08 33.9 0.4 1e-07 32.3 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Tup_N PF08581.5 KNZ81018.1 - 0.26 11.4 2.2 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 Tup N-terminal zf-met PF12874.2 KNZ81019.1 - 0.012 15.7 0.2 0.02 15.0 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Cut8_N PF14482.1 KNZ81019.1 - 0.093 12.7 0.4 0.093 12.7 0.3 2.5 2 0 0 2 2 2 0 Cut8 proteasome-binding domain zf-C2H2_jaz PF12171.3 KNZ81019.1 - 0.099 12.8 0.1 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding SPATIAL PF15256.1 KNZ81019.1 - 0.66 10.0 9.6 0.12 12.4 2.3 2.1 2 0 0 2 2 2 0 SPATIAL CAF-1_p150 PF11600.3 KNZ81019.1 - 4.3 6.6 33.7 0.67 9.3 11.5 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FYDLN_acid PF09538.5 KNZ81019.1 - 8.2 7.0 24.9 0.058 13.9 4.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Carb_kinase PF01256.12 KNZ81020.1 - 0.03 13.6 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase Stn1_C PF12659.2 KNZ81020.1 - 0.083 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH APH PF01636.18 KNZ81021.1 - 1.6e-10 41.1 0.0 4.4e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family gag_pre-integrs PF13976.1 KNZ81022.1 - 5.8e-08 32.2 1.4 1.3e-07 31.1 0.3 2.2 3 0 0 3 3 3 1 GAG-pre-integrase domain Adeno_E3_15_3 PF03307.9 KNZ81022.1 - 0.017 14.8 0.6 0.032 13.9 0.1 1.7 2 0 0 2 2 2 0 Adenovirus 15.3kD protein in E3 region UBN2_3 PF14244.1 KNZ81023.1 - 0.0078 15.7 0.1 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type ArfGap PF01412.13 KNZ81025.1 - 1.8e-21 76.1 0.0 3.2e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Bac_rhamnosid_N PF08531.5 KNZ81027.1 - 2.9e-05 23.6 0.1 0.034 13.6 0.1 3.3 1 1 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain SNF2_N PF00176.18 KNZ81028.1 - 6.1e-73 245.2 0.2 8.8e-73 244.6 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNZ81028.1 - 5.8e-15 54.9 0.0 1.4e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KNZ81028.1 - 1.4e-06 27.3 0.5 9.6e-05 21.3 0.1 2.3 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 PRP38 PF03371.10 KNZ81028.1 - 0.073 12.6 0.1 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 PRP38 family EST1_DNA_bind PF10373.4 KNZ81029.1 - 4.5e-32 111.3 0.0 1.2e-31 109.9 0.0 1.8 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KNZ81029.1 - 6.7e-13 48.7 0.0 3.1e-12 46.6 0.0 2.2 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 KNZ81029.1 - 0.039 13.5 0.2 0.089 12.4 0.1 1.5 1 0 0 1 1 1 0 TPR repeat UCH PF00443.24 KNZ81032.1 - 7.7e-07 28.4 0.0 1.4e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CUE PF02845.11 KNZ81032.1 - 0.0014 18.0 0.0 0.0041 16.5 0.0 1.9 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.1 KNZ81032.1 - 0.031 13.7 0.0 0.087 12.3 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain UBA PF00627.26 KNZ81032.1 - 0.13 12.1 0.2 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Epimerase PF01370.16 KNZ81033.1 - 9e-21 74.3 0.0 2.9e-20 72.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ81033.1 - 1.8e-12 47.6 0.2 7.9e-12 45.5 0.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KNZ81033.1 - 3.8e-11 42.2 0.0 6.7e-11 41.4 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KNZ81033.1 - 6.5e-06 25.2 0.0 0.00026 19.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 KNZ81033.1 - 0.0072 15.3 0.3 0.0095 14.9 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 KNZ81033.1 - 0.025 14.4 0.6 0.056 13.3 0.4 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 KNZ81033.1 - 0.027 13.7 0.2 0.1 11.7 0.4 1.8 2 0 0 2 2 2 0 NmrA-like family Dus PF01207.12 KNZ81034.1 - 6.7e-52 176.2 0.0 1.8e-51 174.7 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) FA_desaturase PF00487.19 KNZ81034.1 - 1.4e-25 90.2 22.7 8.9e-25 87.5 16.5 1.7 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.3 KNZ81034.1 - 6.2e-05 23.0 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) zf-CCCH PF00642.19 KNZ81034.1 - 0.037 13.7 9.1 0.15 11.7 2.5 2.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AMP-binding PF00501.23 KNZ81035.1 - 1.7e-84 283.6 0.0 2e-84 283.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KNZ81035.1 - 2.2e-12 47.7 0.3 5e-12 46.5 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UDPG_MGDP_dh_N PF03721.9 KNZ81036.1 - 5e-58 195.5 0.0 1.1e-57 194.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 KNZ81036.1 - 1.8e-35 121.2 0.2 5.4e-34 116.5 0.1 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 KNZ81036.1 - 6.3e-32 109.6 0.0 1.3e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 KNZ81036.1 - 0.0028 17.4 0.2 0.94 9.1 0.0 2.8 2 1 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldh_1_N PF00056.18 KNZ81036.1 - 0.089 12.6 0.0 5.7 6.7 0.0 2.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KNZ81036.1 - 0.09 13.2 0.4 1.6 9.1 0.0 2.9 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Pkinase_Tyr PF07714.12 KNZ81037.1 - 4.8e-42 143.8 0.0 1.6e-41 142.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KNZ81037.1 - 1.5e-41 142.2 0.0 2.7e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KNZ81037.1 - 0.00049 19.1 0.0 0.00081 18.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF2984 PF11203.3 KNZ81040.1 - 0.4 10.8 6.1 1.1 9.3 4.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2984) Prefoldin PF02996.12 KNZ81040.1 - 0.55 9.8 3.5 0.6 9.7 0.2 2.1 1 1 0 2 2 2 0 Prefoldin subunit SET PF00856.23 KNZ81042.1 - 4e-26 92.2 0.1 4e-26 92.2 0.0 2.6 3 0 0 3 3 3 1 SET domain N-SET PF11764.3 KNZ81042.1 - 4.7e-12 46.1 4.9 4.7e-12 46.1 3.4 3.3 2 2 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N PIG-S PF10510.4 KNZ81042.1 - 0.26 9.8 10.4 0.48 9.0 7.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Membralin PF09746.4 KNZ81042.1 - 0.67 8.9 2.0 1.1 8.2 1.4 1.3 1 0 0 1 1 1 0 Tumour-associated protein DUF4192 PF13830.1 KNZ81042.1 - 6.2 6.3 15.5 0.97 9.0 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) RNase_H PF00075.19 KNZ81045.1 - 1.6e-11 44.6 0.0 2.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 RNase H Aldedh PF00171.17 KNZ81047.1 - 2.9e-102 342.3 0.0 8.1e-63 212.3 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family WD40 PF00400.27 KNZ81048.1 - 1.2e-11 43.9 9.7 0.0035 17.1 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat CDC27 PF09507.5 KNZ81048.1 - 0.18 10.9 14.8 0.24 10.5 10.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.9 KNZ81048.1 - 1.4 6.8 12.5 1.8 6.4 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KNZ81048.1 - 4.3 5.1 19.6 5.7 4.7 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family F-box-like PF12937.2 KNZ81049.1 - 1e-09 37.9 4.5 2.6e-09 36.6 3.1 1.8 1 0 0 1 1 1 1 F-box-like Ribonuc_2-5A PF06479.7 KNZ81050.1 - 1.2e-44 151.2 0.2 8.4e-44 148.5 0.1 2.1 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.20 KNZ81050.1 - 1.6e-37 129.1 0.0 2.5e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81050.1 - 5.2e-19 68.3 0.0 1.3e-17 63.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 KNZ81050.1 - 1.2e-05 24.9 0.0 2.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 KNZ81050.1 - 0.00078 18.8 0.0 0.0037 16.7 0.0 2.2 2 0 0 2 2 2 1 PQQ enzyme repeat DUF2668 PF10873.3 KNZ81051.1 - 0.25 11.4 2.5 0.41 10.8 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) DUF2651 PF10852.3 KNZ81051.1 - 2.5 8.5 8.6 2.2 8.7 1.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2651) MoCF_biosynth PF00994.19 KNZ81052.1 - 2.5e-33 114.4 0.0 5.5e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 Probable molybdopterin binding domain GPI-anchored PF10342.4 KNZ81053.1 - 9.1e-11 42.0 2.1 9.1e-11 42.0 1.4 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Podoplanin PF05808.6 KNZ81053.1 - 0.14 11.7 4.1 0.061 12.8 1.0 1.7 2 0 0 2 2 2 0 Podoplanin MGC-24 PF05283.6 KNZ81053.1 - 8.1 6.1 15.7 1.1 9.0 8.1 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Con-6 PF10346.4 KNZ81054.1 - 4.4e-46 153.9 15.2 2.7e-18 65.0 1.3 3.2 3 0 0 3 3 3 3 Conidiation protein 6 SpoIIIAH PF12685.2 KNZ81054.1 - 0.00034 20.1 1.8 0.14 11.5 0.0 3.0 3 0 0 3 3 3 1 SpoIIIAH-like protein YhzD PF14120.1 KNZ81054.1 - 0.0087 15.9 5.9 8.2 6.4 0.0 3.3 3 0 0 3 3 3 3 YhzD-like protein ERAP1_C PF11838.3 KNZ81054.1 - 0.035 13.3 0.3 0.069 12.3 0.1 1.5 1 1 0 1 1 1 0 ERAP1-like C-terminal domain UpxZ PF06603.6 KNZ81054.1 - 0.1 12.5 0.1 2.2 8.3 0.0 2.1 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists GET2 PF08690.5 KNZ81054.1 - 0.18 11.0 1.0 0.21 10.8 0.7 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 DUF3359 PF11839.3 KNZ81054.1 - 0.3 11.4 7.9 19 5.6 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3359) ATP-synt_DE PF00401.15 KNZ81054.1 - 1.9 8.4 9.1 14 5.6 0.4 3.3 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Pkinase PF00069.20 KNZ81055.1 - 7.5e-29 100.6 0.0 1.6e-28 99.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81055.1 - 6.7e-14 51.5 0.0 3.3e-13 49.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ81055.1 - 3.4e-06 26.2 0.0 1.2e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KNZ81055.1 - 0.075 12.7 0.2 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family WH1 PF00568.18 KNZ81056.1 - 6.1e-06 25.9 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 KNZ81056.1 - 0.0026 18.1 0.1 0.005 17.2 0.1 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain UPF0139 PF03669.8 KNZ81057.1 - 0.034 13.6 0.1 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) ArsB PF02040.10 KNZ81058.1 - 2.5e-12 46.5 23.6 2.7e-10 39.7 8.1 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.11 KNZ81058.1 - 4e-10 38.7 23.7 8e-09 34.5 16.5 2.5 1 1 0 1 1 1 1 Citrate transporter CorA PF01544.13 KNZ81059.1 - 0.00013 21.0 11.7 0.0012 17.9 8.1 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1680 PF07944.7 KNZ81060.1 - 4.1e-22 78.1 0.0 4.7e-21 74.6 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) Gly_transf_sug PF04488.10 KNZ81061.1 - 1.5e-05 25.3 0.1 4.1e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KNZ81061.1 - 0.036 13.2 0.3 0.057 12.5 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein tRNA-synt_2b PF00587.20 KNZ81062.1 - 7.6e-34 116.7 0.0 1.4e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KNZ81062.1 - 1.5e-20 73.1 3.1 1.5e-20 73.1 2.1 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF3829 PF12889.2 KNZ81062.1 - 0.039 13.1 2.4 0.035 13.2 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) SYF2 PF08231.7 KNZ81065.1 - 5.3e-50 169.5 7.4 5.3e-50 169.5 5.1 1.6 2 0 0 2 2 2 1 SYF2 splicing factor 5_nucleotid PF05761.9 KNZ81065.1 - 1 7.7 7.2 1.7 7.0 5.0 1.6 1 1 0 1 1 1 0 5' nucleotidase family Syndecan PF01034.15 KNZ81066.1 - 0.0039 16.7 0.1 0.0067 16.0 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain DUF4328 PF14219.1 KNZ81066.1 - 0.073 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) LRR_6 PF13516.1 KNZ81069.1 - 8.7e-07 28.3 5.9 0.17 12.0 0.1 6.3 7 0 0 7 7 7 1 Leucine Rich repeat LRR_4 PF12799.2 KNZ81069.1 - 4.5e-05 22.9 9.6 0.031 13.9 0.1 4.2 3 2 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNZ81069.1 - 0.0012 18.5 4.8 11 5.8 0.8 4.7 5 0 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.28 KNZ81069.1 - 0.0015 18.2 5.9 14 6.1 0.0 5.6 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 KNZ81069.1 - 0.0077 16.2 7.2 9.3 6.9 0.0 5.3 5 0 0 5 5 5 1 Leucine rich repeat GPI-anchored PF10342.4 KNZ81070.1 - 6.8e-05 23.2 2.6 7.3e-05 23.1 0.0 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family UCR_UQCRX_QCR9 PF05365.7 KNZ81070.1 - 1.7 8.3 4.1 9 6.0 0.0 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like NAD_binding_4 PF07993.7 KNZ81072.1 - 2.9e-31 108.2 0.0 4.4e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KNZ81072.1 - 1e-25 90.0 0.0 3.5e-23 81.6 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 KNZ81072.1 - 5e-06 26.1 0.0 9.7e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KNZ81072.1 - 0.00047 20.1 0.1 0.002 18.0 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase SBP_bac_7 PF03480.8 KNZ81072.1 - 0.038 13.0 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 3Beta_HSD PF01073.14 KNZ81072.1 - 0.048 12.3 0.0 0.12 11.0 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 KNZ81072.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site 2-Hacid_dh_C PF02826.14 KNZ81073.1 - 1.6e-51 173.9 0.0 2.1e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KNZ81073.1 - 1.1e-23 83.2 0.0 4.3e-21 74.7 0.0 2.0 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KNZ81073.1 - 8.4e-08 32.2 0.0 2e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 KNZ81073.1 - 0.014 15.2 0.2 0.089 12.6 0.0 2.1 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_C PF03720.10 KNZ81073.1 - 0.042 14.0 0.0 0.17 12.0 0.0 2.0 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Homeobox_KN PF05920.6 KNZ81073.1 - 0.16 11.6 0.0 9 6.0 0.0 2.4 2 0 0 2 2 2 0 Homeobox KN domain MFS_1 PF07690.11 KNZ81074.1 - 1.8e-27 95.9 19.4 2.6e-27 95.4 13.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KNZ81074.1 - 0.087 12.8 2.2 0.57 10.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) PIF1 PF05970.9 KNZ81075.1 - 3e-11 42.8 0.1 3.4e-11 42.7 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase MTBP_C PF14920.1 KNZ81076.1 - 0.1 12.0 6.5 0.14 11.6 4.5 1.4 1 1 0 1 1 1 0 MDM2-binding DUF230 PF03003.11 KNZ81077.1 - 0.014 14.9 0.8 0.034 13.6 0.2 1.8 2 0 0 2 2 2 0 Poxvirus proteins of unknown function WW PF00397.21 KNZ81078.1 - 0.0036 17.1 1.0 0.0099 15.7 0.0 2.2 2 0 0 2 2 2 1 WW domain NAD_binding_4 PF07993.7 KNZ81080.1 - 5.2e-30 104.1 0.0 7.7e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KNZ81080.1 - 1.7e-29 102.4 0.0 7.7e-27 93.7 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 KNZ81080.1 - 4.4e-06 26.2 0.0 9.2e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KNZ81080.1 - 0.0037 17.4 0.2 0.15 12.3 0.0 2.9 3 0 0 3 3 3 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 KNZ81080.1 - 0.006 16.6 0.0 0.1 12.5 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KNZ81080.1 - 0.011 15.5 0.0 0.12 12.3 0.0 2.4 1 1 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 KNZ81080.1 - 0.016 15.4 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CDO_I PF05995.7 KNZ81080.1 - 0.15 11.2 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 Cysteine dioxygenase type I P35 PF02331.10 KNZ81081.1 - 0.098 11.7 0.3 0.12 11.4 0.2 1.1 1 0 0 1 1 1 0 Apoptosis preventing protein Exo_endo_phos PF03372.18 KNZ81081.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Glyco_transf_8 PF01501.15 KNZ81083.1 - 8.5e-25 87.5 0.0 1.4e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 KNZ81083.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.5 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Molybdopterin PF00384.17 KNZ81084.1 - 7.9e-59 199.5 0.0 1.1e-29 103.5 0.0 2.3 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.1 KNZ81084.1 - 2.1e-19 69.0 0.2 5.5e-19 67.7 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 KNZ81084.1 - 4.9e-19 67.2 0.1 1.3e-18 65.9 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 KNZ81084.1 - 3e-15 56.0 0.0 7.9e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 KNZ81084.1 - 1.1e-08 34.6 0.6 1.1e-08 34.6 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_6 PF12837.2 KNZ81084.1 - 0.38 10.7 3.5 0.44 10.5 1.0 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Aa_trans PF01490.13 KNZ81087.1 - 2.6e-73 246.8 27.7 3e-73 246.6 19.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MIP PF00230.15 KNZ81091.1 - 5.8e-49 166.5 12.0 7e-49 166.3 8.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein PAP2 PF01569.16 KNZ81091.1 - 0.0041 16.8 1.5 0.0041 16.8 1.1 2.5 1 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 KNZ81091.1 - 0.082 13.1 0.4 2.7 8.3 0.0 2.6 2 0 0 2 2 2 0 PAP2 superfamily C-terminal MIP PF00230.15 KNZ81092.1 - 1.7e-52 178.1 10.3 1.9e-52 178.0 7.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF2721 PF11026.3 KNZ81092.1 - 0.25 11.0 1.7 1.7 8.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) PAP2 PF01569.16 KNZ81092.1 - 0.37 10.4 7.8 0.18 11.4 3.1 2.2 1 1 1 2 2 2 0 PAP2 superfamily MIP PF00230.15 KNZ81093.1 - 2.1e-52 177.8 12.1 2.3e-52 177.6 8.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein PAP2 PF01569.16 KNZ81093.1 - 0.011 15.3 2.3 0.011 15.3 1.6 2.5 1 1 1 2 2 2 0 PAP2 superfamily Phage_integrase PF00589.17 KNZ81095.1 - 0.00025 20.7 0.0 0.00073 19.2 0.0 1.8 1 1 0 1 1 1 1 Phage integrase family Pectate_lyase PF03211.8 KNZ81098.1 - 5.2e-65 218.8 2.9 8.6e-65 218.1 2.0 1.3 1 0 0 1 1 1 1 Pectate lyase MFS_1 PF07690.11 KNZ81098.1 - 1.5e-25 89.6 30.9 2.4e-25 89.0 21.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DDE_1 PF03184.14 KNZ81098.1 - 5.9e-22 77.8 2.2 6.8e-19 67.8 0.2 2.5 1 1 1 2 2 2 2 DDE superfamily endonuclease DUF1352 PF07086.7 KNZ81098.1 - 0.22 11.1 1.6 0.49 9.9 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) TPR_14 PF13428.1 KNZ81099.1 - 2.8e-10 39.8 4.0 0.0012 19.3 0.0 5.3 3 1 3 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ81099.1 - 5.5e-09 35.5 0.0 6.6e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 KNZ81099.1 - 8.1e-09 35.9 0.0 0.00059 20.4 0.0 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ81099.1 - 1.4e-08 34.9 0.1 0.015 15.6 0.0 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ81099.1 - 1.8e-06 27.3 0.0 0.0089 15.8 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ81099.1 - 5.8e-06 25.6 0.0 0.0032 17.0 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ81099.1 - 0.00013 21.7 0.1 1.2 9.0 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ81099.1 - 0.00019 21.3 0.0 1.7 9.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 KNZ81099.1 - 0.00049 19.2 0.4 0.058 12.4 0.1 3.1 1 1 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 KNZ81099.1 - 0.00078 19.5 0.0 0.016 15.3 0.0 2.5 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KNZ81099.1 - 0.0011 18.5 0.0 0.36 10.7 0.0 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Imm43 PF15602.1 KNZ81099.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.6 1 1 0 1 1 1 1 Immunity protein 43 TPR_12 PF13424.1 KNZ81099.1 - 0.012 15.5 0.3 0.21 11.5 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ81099.1 - 0.015 15.0 0.1 0.89 9.5 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ81099.1 - 0.04 14.3 2.8 12 6.6 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat DHH PF01368.15 KNZ81100.1 - 8e-11 41.7 0.0 1.4e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.9 KNZ81100.1 - 1e-10 41.9 0.0 2.8e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 DHHA2 domain Hexose_dehydrat PF03559.9 KNZ81101.1 - 0.054 12.5 1.0 0.057 12.4 0.0 1.5 2 0 0 2 2 2 0 NDP-hexose 2,3-dehydratase SRCR PF00530.13 KNZ81102.1 - 0.06 13.6 3.0 0.071 13.4 0.5 2.1 1 1 1 2 2 2 0 Scavenger receptor cysteine-rich domain zf-CCHC PF00098.18 KNZ81105.1 - 0.026 14.4 0.5 0.05 13.5 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.1 KNZ81106.1 - 3.1e-06 27.6 0.0 5.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ81106.1 - 0.0012 18.3 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.3 KNZ81106.1 - 0.038 13.3 0.1 0.049 12.9 0.1 1.1 1 0 0 1 1 1 0 Ty3 transposon peptidase Kelch_6 PF13964.1 KNZ81106.1 - 0.13 12.4 0.2 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 Kelch motif rve PF00665.21 KNZ81107.1 - 0.02 15.0 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Asp_protease_2 PF13650.1 KNZ81109.1 - 0.00048 20.5 0.0 0.00073 19.9 0.0 1.3 1 1 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 KNZ81110.1 - 0.026 14.4 0.4 0.026 14.4 0.3 1.9 2 0 0 2 2 2 0 Zinc knuckle Peptidase_S41 PF03572.13 KNZ81111.1 - 0.00061 19.2 0.0 0.0014 18.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 WD40 PF00400.27 KNZ81112.1 - 2.3e-08 33.5 0.8 0.00094 18.9 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat Borrelia_orfX PF04160.7 KNZ81112.1 - 0.048 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Orf-X protein TBCC PF07986.7 KNZ81114.1 - 2.4e-25 88.2 0.1 3.9e-25 87.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C ParBc PF02195.13 KNZ81115.1 - 0.033 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 ParB-like nuclease domain HSP20 PF00011.16 KNZ81117.1 - 1.6e-07 31.0 0.0 0.022 14.6 0.0 2.8 2 1 0 2 2 2 2 Hsp20/alpha crystallin family CSTF2_hinge PF14327.1 KNZ81118.1 - 3.8e-24 84.5 5.9 3.8e-24 84.5 4.1 1.8 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KNZ81118.1 - 2e-19 68.9 0.0 3.1e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ81118.1 - 4.4e-14 52.1 0.0 1.3e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ81118.1 - 4.8e-08 32.7 0.0 9.3e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KNZ81118.1 - 1e-07 31.1 1.6 3e-07 29.5 1.1 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal DUF1421 PF07223.6 KNZ81118.1 - 6.4 6.4 51.4 8.7 6.0 35.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) tRNA-synt_2b PF00587.20 KNZ81119.1 - 5.5e-46 156.3 0.1 9.6e-46 155.5 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KNZ81119.1 - 7e-18 64.3 0.3 3.1e-17 62.3 0.2 2.0 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.16 KNZ81119.1 - 5.5e-12 45.3 0.0 1.1e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 KNZ81119.1 - 5.9e-11 42.0 0.0 1.1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Pkinase PF00069.20 KNZ81120.1 - 2.8e-21 75.8 0.0 4.6e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KNZ81120.1 - 9.1e-17 60.2 14.9 1.9e-08 33.8 0.6 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat HEAT PF02985.17 KNZ81120.1 - 3.4e-16 57.7 9.8 0.00065 19.5 0.1 6.0 5 0 0 5 5 5 4 HEAT repeat Pkinase_Tyr PF07714.12 KNZ81120.1 - 2.5e-09 36.6 0.0 3.6e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 KNZ81120.1 - 2.3e-07 30.9 0.7 0.062 13.5 0.0 3.4 2 1 1 3 3 3 3 HEAT repeats Vac14_Fab1_bd PF12755.2 KNZ81120.1 - 0.0029 17.9 1.1 2.2 8.7 0.0 2.9 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KNZ81120.1 - 0.017 15.0 4.2 2.2 8.1 0.2 3.4 2 2 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 KNZ81120.1 - 0.082 12.8 0.7 14 5.7 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 KNZ81120.1 - 0.22 12.0 3.8 0.87 10.1 0.2 3.3 3 0 0 3 3 3 0 HEAT-like repeat DUF2639 PF11121.3 KNZ81120.1 - 0.25 10.8 0.1 0.76 9.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) DUF1308 PF07000.6 KNZ81121.1 - 1.3e-22 80.0 0.0 2.8e-22 78.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) HSP20 PF00011.16 KNZ81125.1 - 2.8e-23 81.6 0.1 3.7e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 KNZ81125.1 - 0.0021 18.5 0.0 0.004 17.6 0.0 1.4 1 1 0 1 1 1 1 CS domain DUF4097 PF13349.1 KNZ81125.1 - 0.0037 16.8 0.0 0.0052 16.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4097) Abhydrolase_6 PF12697.2 KNZ81126.1 - 1e-15 58.2 1.0 4.3e-15 56.2 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ81126.1 - 1.4e-07 31.3 0.0 2.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ81126.1 - 6.3e-06 25.9 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KNZ81126.1 - 0.0091 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 KNZ81126.1 - 0.0093 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase PAF-AH_p_II PF03403.8 KNZ81126.1 - 0.061 11.6 0.0 0.089 11.0 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.20 KNZ81126.1 - 0.08 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 KNZ81126.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 KNZ81127.1 - 4.4e-15 56.1 0.4 1.8e-14 54.1 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ81127.1 - 2.2e-06 27.4 0.0 4.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ81127.1 - 4.6e-05 23.2 0.0 9.3e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ81127.1 - 0.0049 16.1 0.0 0.0078 15.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ndr PF03096.9 KNZ81127.1 - 0.043 12.2 0.0 1.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Ndr family Esterase PF00756.15 KNZ81127.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Epimerase PF01370.16 KNZ81128.1 - 2.7e-11 43.3 0.1 5.1e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ81128.1 - 2.4e-07 30.9 1.3 9.5e-07 28.9 0.5 1.9 1 1 1 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 KNZ81128.1 - 5.7e-05 22.2 0.1 8.6e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KNZ81128.1 - 0.00025 19.8 0.0 0.00089 18.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KNZ81128.1 - 0.0028 16.9 0.1 0.0042 16.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KNZ81128.1 - 0.0052 15.7 0.1 0.39 9.5 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein F420_oxidored PF03807.12 KNZ81128.1 - 0.03 14.7 0.1 0.14 12.6 0.0 1.9 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KNZ81128.1 - 0.05 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.17 KNZ81129.1 - 3.5e-43 147.8 0.0 4.2e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-rbx1 PF12678.2 KNZ81130.1 - 1.5e-34 117.9 13.8 1.9e-34 117.6 9.6 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KNZ81130.1 - 1e-16 60.5 9.5 1.4e-16 60.1 6.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KNZ81130.1 - 1.4e-06 28.0 12.7 9.5e-06 25.3 8.8 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KNZ81130.1 - 0.00093 18.8 11.0 0.009 15.6 7.6 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNZ81130.1 - 0.0032 17.1 9.6 0.28 10.8 6.8 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ81130.1 - 0.017 15.0 11.3 0.58 10.2 7.8 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KNZ81130.1 - 0.32 10.9 9.7 1.7 8.6 6.9 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 KNZ81130.1 - 0.8 9.7 9.8 1.5 8.8 6.8 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KNZ81130.1 - 0.98 9.6 11.0 37 4.5 7.6 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.1 KNZ81130.1 - 1.5 8.5 10.8 20 5.0 7.5 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 KNZ81130.1 - 4.6 7.0 6.5 1.3 8.8 1.6 2.1 1 1 1 2 2 2 0 RING-type zinc-finger Exonuc_VII_L PF02601.10 KNZ81131.1 - 1.5 7.9 15.0 40 3.2 10.6 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit HSP20 PF00011.16 KNZ81132.1 - 4e-23 81.2 0.1 5.2e-23 80.8 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 KNZ81132.1 - 0.0014 19.1 0.0 0.0027 18.2 0.0 1.4 1 1 0 1 1 1 1 CS domain DUF4097 PF13349.1 KNZ81132.1 - 0.0025 17.3 0.1 0.0035 16.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4097) HSP20 PF00011.16 KNZ81133.1 - 4.7e-23 80.9 0.0 6.1e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 KNZ81133.1 - 0.00037 20.9 0.0 0.00057 20.3 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF4097 PF13349.1 KNZ81133.1 - 0.0006 19.3 0.1 0.0008 18.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4097) PIH1 PF08190.7 KNZ81133.1 - 0.058 12.8 0.0 0.073 12.5 0.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 HSP20 PF00011.16 KNZ81134.1 - 4.5e-23 81.0 0.1 5.9e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 KNZ81134.1 - 0.0019 18.6 0.0 0.0037 17.7 0.0 1.4 1 1 0 1 1 1 1 CS domain DUF4097 PF13349.1 KNZ81134.1 - 0.0057 16.2 0.0 0.0077 15.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4097) PIH1 PF08190.7 KNZ81134.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Piwi PF02171.12 KNZ81136.1 - 2.3e-82 276.3 0.0 3.2e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KNZ81136.1 - 4.6e-21 74.5 0.0 8.4e-21 73.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KNZ81136.1 - 1.3e-17 62.8 0.1 3.3e-17 61.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) ApbA PF02558.11 KNZ81137.1 - 2.7e-15 56.1 0.0 4.3e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KNZ81137.1 - 2.2e-14 53.5 0.0 5.6e-12 45.7 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA C terminal IlvN PF07991.7 KNZ81137.1 - 0.016 14.5 0.1 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain FAD_binding_3 PF01494.14 KNZ81137.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 KNZ81137.1 - 0.15 11.9 0.2 0.36 10.6 0.2 1.7 1 0 0 1 1 1 0 ThiF family Saccharop_dh PF03435.13 KNZ81137.1 - 0.18 10.7 0.2 0.45 9.4 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase Pkinase PF00069.20 KNZ81139.1 - 3.1e-64 216.6 0.0 3.9e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81139.1 - 1.4e-25 89.8 0.0 1.8e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ81139.1 - 0.15 11.7 0.1 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribonuclease_3 PF00636.21 KNZ81140.1 - 5.8e-13 49.2 4.7 1.1e-07 32.3 0.0 3.2 3 1 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KNZ81140.1 - 2.1e-09 37.4 0.0 4.6e-07 29.8 0.0 2.6 2 1 0 2 2 2 2 Ribonuclease-III-like zf-CCHC PF00098.18 KNZ81141.1 - 0.016 15.0 5.6 0.016 15.0 3.9 3.0 3 0 0 3 3 3 0 Zinc knuckle DUF3680 PF12441.3 KNZ81142.1 - 0.058 13.2 0.1 0.65 9.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3680) Herpes_Helicase PF02689.9 KNZ81146.1 - 9.2e-08 30.3 0.0 9.7e-08 30.2 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 KNZ81146.1 - 0.0055 16.8 0.0 0.0088 16.1 0.0 1.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF3340 PF11818.3 KNZ81147.1 - 0.0065 16.4 1.5 0.012 15.5 1.0 1.3 1 0 0 1 1 1 1 C-terminal domain of tail specific protease (DUF3340) DUF4337 PF14235.1 KNZ81147.1 - 0.011 15.6 0.1 0.019 14.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) UBN2_2 PF14227.1 KNZ81148.1 - 1.2e-07 31.2 0.2 2.1e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ81148.1 - 4.2e-05 23.3 0.1 8.3e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HEAT PF02985.17 KNZ81149.1 - 6.5e-12 44.4 7.8 3.2e-05 23.6 0.1 5.7 5 0 0 5 5 5 3 HEAT repeat Arm PF00514.18 KNZ81149.1 - 1.1e-11 44.1 9.3 0.013 15.3 0.0 5.9 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KNZ81149.1 - 4.8e-08 33.1 9.4 0.13 12.5 0.3 4.3 3 2 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 KNZ81149.1 - 3.5e-07 30.5 11.8 0.032 14.7 0.0 5.8 5 1 1 6 6 6 3 HEAT-like repeat Atx10homo_assoc PF09759.4 KNZ81149.1 - 0.037 13.7 0.0 3.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain PIF1 PF05970.9 KNZ81150.1 - 7.3e-10 38.3 0.0 7.3e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_11 PF13086.1 KNZ81150.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 2 0 0 2 2 2 0 AAA domain Asp_protease_2 PF13650.1 KNZ81153.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.1 KNZ81153.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Pkinase PF00069.20 KNZ81154.1 - 3.2e-36 124.7 0.8 1.3e-34 119.5 0.2 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81154.1 - 1.3e-17 63.7 0.0 1.9e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ81154.1 - 1.9e-06 27.0 0.0 2.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Sp100 PF03172.8 KNZ81155.1 - 0.044 13.7 0.9 0.098 12.6 0.2 1.9 1 1 0 1 1 1 0 Sp100 domain Propep_M14 PF02244.11 KNZ81155.1 - 0.58 9.8 0.1 0.58 9.8 0.1 3.7 3 1 1 4 4 4 0 Carboxypeptidase activation peptide CENP-F_leu_zip PF10473.4 KNZ81155.1 - 0.8 9.5 44.9 0.18 11.6 2.4 3.7 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF591 PF04569.9 KNZ81156.1 - 0.029 14.3 7.7 1.3 9.1 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function tRNA-synt_1c PF00749.16 KNZ81156.1 - 0.33 9.5 11.0 0.35 9.4 1.7 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Stimulus_sens_1 PF13756.1 KNZ81156.1 - 0.84 10.0 3.5 20 5.6 0.2 2.5 2 0 0 2 2 2 0 Stimulus-sensing domain Ima1_N PF09779.4 KNZ81156.1 - 2.2 8.7 7.8 12 6.3 1.3 2.2 1 1 1 2 2 2 0 Ima1 N-terminal domain Dicty_REP PF05086.7 KNZ81156.1 - 4.4 4.9 9.6 5.4 4.6 6.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PIF1 PF05970.9 KNZ81158.1 - 1.9e-39 135.6 0.0 2.2e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ81158.1 - 0.0038 16.8 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KNZ81158.1 - 0.0088 15.5 0.1 0.021 14.3 0.1 1.7 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KNZ81158.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KNZ81158.1 - 0.054 13.6 0.1 0.3 11.2 0.1 2.1 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KNZ81158.1 - 0.066 12.6 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KNZ81158.1 - 0.068 13.1 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Torsin PF06309.6 KNZ81158.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA PF00004.24 KNZ81158.1 - 0.13 12.4 0.2 1.8 8.7 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-RVT PF13966.1 KNZ81159.1 - 0.0096 16.2 3.3 0.021 15.1 2.3 1.7 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase UBN2_2 PF14227.1 KNZ81160.1 - 0.04 13.4 0.0 0.89 9.1 0.0 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ81160.1 - 0.076 12.8 0.0 3.9 7.2 0.0 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Copper-fist PF00649.13 KNZ81160.1 - 2.2 7.5 4.8 3.7 6.8 0.7 2.3 2 0 0 2 2 2 0 Copper fist DNA binding domain Mg_trans_NIPA PF05653.9 KNZ81161.1 - 2e-24 86.1 6.4 2.7e-24 85.6 4.4 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Tetraspannin PF00335.15 KNZ81161.1 - 0.026 13.8 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family HEAT_EZ PF13513.1 KNZ81162.1 - 5.7e-07 29.8 1.1 0.007 16.8 0.0 4.2 4 0 0 4 4 4 2 HEAT-like repeat Sulfatase PF00884.18 KNZ81163.1 - 0.036 13.2 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Sulfatase SNF2_N PF00176.18 KNZ81164.1 - 5.1e-37 127.2 0.2 7.6e-37 126.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 KNZ81164.1 - 0.00015 20.6 0.1 0.0015 17.4 0.0 2.1 1 1 1 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.24 KNZ81164.1 - 0.00024 20.7 8.7 0.00024 20.7 6.0 2.9 2 1 1 3 3 3 1 PHD-finger DUF3384 PF11864.3 KNZ81164.1 - 0.022 13.2 0.4 0.052 12.0 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) Helicase_C PF00271.26 KNZ81164.1 - 0.023 14.5 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 Helicase conserved C-terminal domain RINGv PF12906.2 KNZ81165.1 - 9.3e-09 35.1 2.6 1.2e-08 34.7 1.8 1.2 1 0 0 1 1 1 1 RING-variant domain DUF2207 PF09972.4 KNZ81165.1 - 0.061 11.9 0.7 0.066 11.7 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2545 PF10810.3 KNZ81165.1 - 1 9.8 5.1 1.5 9.2 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2545) Peptidase_M28 PF04389.12 KNZ81166.1 - 1.2e-24 87.0 0.1 2.1e-24 86.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KNZ81166.1 - 2.2e-05 24.0 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KNZ81166.1 - 0.0038 16.0 0.0 0.017 13.8 0.0 1.8 1 1 0 2 2 2 1 M42 glutamyl aminopeptidase PAT1 PF09770.4 KNZ81167.1 - 9.3 4.3 13.3 12 3.9 9.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-box-like PF12937.2 KNZ81168.1 - 8.1e-05 22.2 0.2 0.00025 20.7 0.1 2.0 1 0 0 1 1 1 1 F-box-like APH PF01636.18 KNZ81170.1 - 1.9e-07 31.0 0.0 3.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2360 PF10152.4 KNZ81171.1 - 0.0016 18.7 4.0 0.0022 18.3 2.8 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Reo_sigmaC PF04582.7 KNZ81171.1 - 0.0072 15.5 1.0 0.0081 15.3 0.7 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Allexi_40kDa PF05549.6 KNZ81171.1 - 0.041 13.1 1.6 0.058 12.6 1.1 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF745 PF05335.8 KNZ81171.1 - 0.045 13.2 4.0 0.077 12.5 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.2 KNZ81171.1 - 0.047 13.5 0.3 0.047 13.5 0.2 1.4 2 0 0 2 2 2 0 Tropomyosin like SlyX PF04102.7 KNZ81171.1 - 0.063 13.6 4.3 3.9 7.9 0.4 2.4 1 1 1 2 2 2 0 SlyX His_Phos_1 PF00300.17 KNZ81171.1 - 0.087 12.9 0.0 0.099 12.7 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) CENP-F_leu_zip PF10473.4 KNZ81171.1 - 0.17 11.7 1.5 0.31 10.8 1.0 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pol_alpha_B_N PF08418.5 KNZ81171.1 - 5.1 6.5 11.1 0.24 10.8 0.2 2.1 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal Ank_2 PF12796.2 KNZ81172.1 - 1.2e-85 281.9 41.1 2.2e-19 69.6 2.8 3.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNZ81172.1 - 8.3e-56 185.4 29.0 1.5e-12 47.6 0.9 5.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 KNZ81172.1 - 4.9e-49 161.7 26.8 1.8e-10 40.0 0.2 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 KNZ81172.1 - 5.7e-40 134.4 31.7 3.7e-12 46.0 0.5 6.0 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ81172.1 - 6e-34 112.6 18.7 1.3e-06 28.0 0.2 7.1 7 0 0 7 7 7 6 Ankyrin repeat DUF3797 PF12677.2 KNZ81172.1 - 0.098 12.2 2.5 0.44 10.2 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) DUF1110 PF06533.7 KNZ81172.1 - 0.44 10.3 8.5 8 6.2 0.3 3.6 1 1 2 4 4 4 0 Protein of unknown function (DUF1110) Cys_Met_Meta_PP PF01053.15 KNZ81173.1 - 6.4e-123 409.8 0.0 2e-92 309.4 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KNZ81173.1 - 0.016 14.2 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KNZ81173.1 - 0.033 13.1 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II HsbA PF12296.3 KNZ81174.1 - 0.057 13.2 0.0 0.13 12.1 0.0 1.5 2 0 0 2 2 2 0 Hydrophobic surface binding protein A PocR PF10114.4 KNZ81174.1 - 0.11 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Sensory domain found in PocR MatE PF01554.13 KNZ81176.1 - 4.6e-19 68.6 5.7 4.6e-19 68.6 3.9 2.2 2 1 0 2 2 2 1 MatE PLDc_2 PF13091.1 KNZ81177.1 - 1e-14 54.3 0.0 3.5e-07 29.9 0.0 3.3 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.17 KNZ81177.1 - 3.7e-13 48.7 4.0 7.8e-08 31.8 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif BAP PF06639.6 KNZ81178.1 - 0.19 11.4 1.3 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) Aldo_ket_red PF00248.16 KNZ81179.1 - 2.3e-40 138.2 0.0 2.8e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Gag_p19 PF02228.11 KNZ81179.1 - 0.026 14.8 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Major core protein p19 CPSase_sm_chain PF00988.17 KNZ81179.1 - 0.11 11.9 0.1 3.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase small chain, CPSase domain Pro_isomerase PF00160.16 KNZ81180.1 - 1.2e-44 152.2 0.2 1.6e-44 151.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GMC_oxred_N PF00732.14 KNZ81183.1 - 8.2e-63 212.3 0.0 1.2e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ81183.1 - 4.6e-28 98.3 0.0 9.9e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KNZ81183.1 - 1.8e-05 23.8 0.1 2.9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KNZ81183.1 - 0.0014 17.6 0.7 0.25 10.1 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ81183.1 - 0.0028 16.5 0.2 0.061 12.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KNZ81183.1 - 0.0062 16.4 0.1 0.014 15.2 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KNZ81183.1 - 0.0068 15.5 0.1 0.03 13.4 0.0 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 KNZ81183.1 - 0.029 13.2 0.1 0.8 8.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KNZ81183.1 - 0.11 11.0 0.9 0.18 10.2 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF768 PF05589.6 KNZ81183.1 - 0.36 10.8 1.8 6.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF768) PIP5K PF01504.13 KNZ81184.1 - 9.2e-50 169.0 0.1 1.6e-49 168.2 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Med2 PF11214.3 KNZ81184.1 - 0.071 13.1 1.0 0.2 11.7 0.7 1.7 1 0 0 1 1 1 0 Mediator complex subunit 2 Homeobox PF00046.24 KNZ81186.1 - 4.9e-10 38.8 0.1 1.8e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 Homeobox domain adh_short PF00106.20 KNZ81187.1 - 3.5e-13 49.8 0.6 4.6e-13 49.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ81187.1 - 3.3e-07 30.3 0.1 4.4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.10 KNZ81187.1 - 0.017 14.7 0.1 0.04 13.5 0.0 1.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus Shikimate_DH PF01488.15 KNZ81187.1 - 0.1 12.6 0.1 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KNZ81187.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3813 PF12758.2 KNZ81188.1 - 0.018 15.1 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) Phage_fiber PF03335.8 KNZ81188.1 - 0.11 12.1 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Phage tail fibre repeat SET PF00856.23 KNZ81189.1 - 1.1e-12 48.5 0.0 2.4e-11 44.2 0.0 2.1 1 1 0 1 1 1 1 SET domain VWA PF00092.23 KNZ81190.1 - 2e-08 34.1 0.0 4.6e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KNZ81190.1 - 5.9e-07 29.7 0.0 8.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KNZ81190.1 - 5.6e-05 23.0 0.1 0.00012 21.9 0.0 1.6 1 1 0 1 1 1 1 vWA found in TerF C terminus Copine PF07002.11 KNZ81190.1 - 0.00016 21.4 0.0 0.0011 18.7 0.0 1.9 1 1 1 2 2 2 1 Copine FlaE PF07559.9 KNZ81190.1 - 0.019 15.6 0.0 0.054 14.1 0.0 1.7 2 1 0 2 2 2 0 Flagellar basal body protein FlaE Helitron_like_N PF14214.1 KNZ81191.1 - 4.5e-63 212.3 0.3 9.8e-63 211.2 0.1 1.6 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 KNZ81191.1 - 0.055 12.1 0.0 0.095 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) DUF3296 PF11726.3 KNZ81191.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) PIF1 PF05970.9 KNZ81193.1 - 2.4e-11 43.2 0.0 2.9e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.1 KNZ81193.1 - 0.0004 20.4 0.0 0.00043 20.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.10 KNZ81193.1 - 0.0035 17.1 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KNZ81193.1 - 0.005 16.9 0.0 0.011 15.9 0.0 1.5 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.1 KNZ81193.1 - 0.007 15.9 0.0 0.0087 15.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ81193.1 - 0.0098 16.7 0.4 0.038 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KNZ81193.1 - 0.016 15.4 0.5 0.3 11.3 0.0 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KNZ81193.1 - 0.024 13.8 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.1 KNZ81193.1 - 0.03 14.4 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KNZ81193.1 - 0.034 14.4 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 KNZ81193.1 - 0.04 14.2 0.2 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 KNZ81193.1 - 0.063 12.7 0.1 0.075 12.5 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2791 PF10923.3 KNZ81193.1 - 0.065 11.8 0.0 0.076 11.5 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Viral_helicase1 PF01443.13 KNZ81193.1 - 0.067 12.7 0.1 0.086 12.3 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.6 KNZ81193.1 - 0.095 12.5 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Torsin KAP_NTPase PF07693.9 KNZ81193.1 - 0.1 11.5 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Herpes_Helicase PF02689.9 KNZ81194.1 - 3.3e-05 21.8 0.0 3.4e-05 21.8 0.0 1.0 1 0 0 1 1 1 1 Helicase Helitron_like_N PF14214.1 KNZ81195.1 - 2.8e-17 63.0 0.1 3.5e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ81195.1 - 0.011 15.3 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) Gemini_AL1 PF00799.15 KNZ81195.1 - 0.018 14.8 0.1 0.021 14.6 0.1 1.1 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain Helitron_like_N PF14214.1 KNZ81196.1 - 2.3e-16 60.0 0.0 1.1e-15 57.8 0.0 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Patatin PF01734.17 KNZ81199.1 - 1e-17 64.7 0.0 4.1e-17 62.7 0.0 2.0 2 1 0 2 2 2 1 Patatin-like phospholipase Mqo PF06039.10 KNZ81199.1 - 0.034 12.3 0.0 0.053 11.6 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) RicinB_lectin_2 PF14200.1 KNZ81201.1 - 6.4e-07 29.7 0.1 1.3e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like FGF PF00167.13 KNZ81201.1 - 0.014 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Fibroblast growth factor p450 PF00067.17 KNZ81202.1 - 9.4e-52 176.0 3.2 1.7e-31 109.2 0.1 3.0 3 0 0 3 3 3 3 Cytochrome P450 DUF4066 PF13278.1 KNZ81203.1 - 8.4e-21 73.9 0.0 1e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KNZ81203.1 - 1.2e-10 40.9 0.0 1.5e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Lipase_chap PF03280.9 KNZ81203.1 - 0.089 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein FGGY_C PF02782.11 KNZ81204.1 - 0.0081 15.7 0.1 0.078 12.5 0.0 2.6 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain RVT_2 PF07727.9 KNZ81205.1 - 0.00052 19.0 0.0 0.001 18.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.17 KNZ81206.1 - 7.1e-74 248.9 0.0 8.6e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TBPIP PF07106.8 KNZ81209.1 - 2.8e-38 131.1 0.6 3.4e-38 130.8 0.4 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Penicillinase_R PF03965.11 KNZ81209.1 - 0.00055 20.0 0.0 0.0011 19.0 0.0 1.5 1 1 0 1 1 1 1 Penicillinase repressor Med4 PF10018.4 KNZ81209.1 - 0.007 15.7 0.7 0.012 15.0 0.5 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 HTH_IclR PF09339.5 KNZ81209.1 - 0.033 13.7 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain EURL PF06937.6 KNZ81209.1 - 0.049 13.0 0.2 0.076 12.4 0.1 1.3 1 0 0 1 1 1 0 EURL protein XkdW PF09636.5 KNZ81209.1 - 0.48 10.3 2.2 0.64 9.9 0.4 2.1 2 1 1 3 3 3 0 XkdW protein Mito_carr PF00153.22 KNZ81210.1 - 7.6e-58 192.2 0.4 2.5e-22 78.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 KNZ81211.1 - 1.4e-11 43.7 0.1 2.3e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.2 KNZ81212.1 - 2.4e-26 91.9 0.5 4.4e-13 49.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ81212.1 - 1.8e-20 71.6 6.4 4.2e-09 35.7 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KNZ81212.1 - 1.1e-18 67.2 1.0 5.3e-09 36.3 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ81212.1 - 1.6e-17 61.8 1.0 7.3e-06 25.7 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KNZ81212.1 - 2.4e-17 62.5 2.4 2.9e-07 30.4 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Pkinase PF00069.20 KNZ81213.1 - 2.6e-10 39.8 0.0 3.8e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81213.1 - 0.079 12.0 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF1539 PF07560.6 KNZ81214.1 - 0.13 12.1 0.1 0.17 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) PPTA PF01239.17 KNZ81215.1 - 0.094 12.1 0.1 0.27 10.6 0.1 1.8 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat Pkinase PF00069.20 KNZ81216.1 - 8.1e-08 31.7 0.0 1.3e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Prominin PF05478.6 KNZ81217.1 - 0.079 10.4 0.2 0.097 10.1 0.2 1.1 1 0 0 1 1 1 0 Prominin Pkinase PF00069.20 KNZ81218.1 - 1.3e-10 40.8 0.0 1.5e-08 34.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81218.1 - 0.00072 18.6 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KNZ81219.1 - 0.00012 21.3 0.2 0.022 13.9 0.2 2.5 2 1 0 2 2 2 2 Protein kinase domain Evr1_Alr PF04777.8 KNZ81220.1 - 3.2e-21 75.0 0.1 4.4e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Erv1 / Alr family OPT PF03169.10 KNZ81221.1 - 1.7e-184 614.8 45.9 2.4e-184 614.3 31.8 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein LSM PF01423.17 KNZ81222.1 - 2e-15 56.0 0.1 3.5e-15 55.3 0.0 1.4 2 0 0 2 2 2 1 LSM domain LRR_8 PF13855.1 KNZ81223.1 - 0.0044 16.7 0.2 0.097 12.4 0.1 3.3 3 1 0 3 3 3 1 Leucine rich repeat CK2S PF15011.1 KNZ81223.1 - 0.083 12.6 0.1 13 5.4 0.0 2.6 3 0 0 3 3 3 0 Casein Kinase 2 substrate LRR_4 PF12799.2 KNZ81223.1 - 0.24 11.0 3.7 48 3.7 0.0 4.8 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) TP_methylase PF00590.15 KNZ81224.1 - 1.6e-16 60.6 0.0 3.3e-16 59.6 0.0 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases tRNA-synt_2 PF00152.15 KNZ81225.1 - 1e-70 238.1 0.0 1.6e-70 237.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KNZ81225.1 - 1.5e-11 43.9 0.1 2.6e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ATP-synt_B PF00430.13 KNZ81225.1 - 1.1 9.0 9.0 2.1 8.1 6.2 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) COesterase PF00135.23 KNZ81226.1 - 8.7e-69 232.6 0.0 5.3e-59 200.3 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ81226.1 - 1.8e-07 30.9 0.0 7e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ81226.1 - 0.0024 17.6 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ81226.1 - 0.0047 16.8 0.3 0.0068 16.3 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ81226.1 - 0.047 12.8 0.1 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.4 KNZ81226.1 - 0.092 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase COesterase PF00135.23 KNZ81227.1 - 8e-151 503.3 0.1 1.1e-75 255.3 0.0 4.6 3 2 1 4 4 4 4 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ81227.1 - 1.7e-19 70.2 0.0 7.7e-09 35.4 0.0 3.5 2 2 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ81227.1 - 4.5e-08 32.9 0.0 0.0062 16.2 0.0 3.1 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KNZ81227.1 - 3.5e-06 27.0 0.1 0.21 11.4 0.0 3.3 3 0 0 3 3 3 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ81227.1 - 1.3e-05 24.4 0.2 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF2424 PF10340.4 KNZ81227.1 - 0.073 11.7 0.1 4.1 5.9 0.0 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF2424) PAE PF03283.8 KNZ81227.1 - 0.12 10.9 0.1 0.84 8.2 0.0 2.0 2 0 0 2 2 2 0 Pectinacetylesterase Mito_carr PF00153.22 KNZ81228.1 - 6.3e-40 134.7 0.1 8.1e-14 51.1 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein 3HCDH_N PF02737.13 KNZ81229.1 - 1.1e-48 165.2 2.3 5.1e-48 163.0 1.6 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KNZ81229.1 - 3.5e-22 78.6 0.0 7.9e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KNZ81229.1 - 0.00057 19.7 0.1 0.0014 18.4 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KNZ81229.1 - 0.041 13.0 0.1 0.073 12.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.20 KNZ81230.1 - 2.4e-10 40.0 0.0 3.5e-08 32.8 0.0 2.2 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81230.1 - 7.2e-05 21.9 0.0 0.0044 16.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Sulfate_transp PF00916.15 KNZ81232.1 - 2.9e-55 187.2 11.2 2.9e-55 187.2 7.7 2.4 2 2 2 4 4 4 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KNZ81232.1 - 1.3e-25 88.8 6.0 5.3e-25 86.9 4.1 2.1 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KNZ81232.1 - 1.5e-18 66.2 0.0 5e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.1 KNZ81232.1 - 3.4e-06 26.9 0.0 1.2e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 STAS domain Cyclase PF04199.8 KNZ81233.1 - 2.2e-37 128.3 0.0 2.8e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase Peptidase_S8 PF00082.17 KNZ81234.1 - 5.7e-54 183.1 2.1 7.8e-54 182.7 1.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KNZ81234.1 - 1.5e-14 54.3 0.1 3.2e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Acetyltransf_1 PF00583.19 KNZ81235.1 - 3.7e-07 30.0 0.1 1.1e-06 28.6 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KNZ81235.1 - 2.1e-06 27.3 0.0 4.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KNZ81235.1 - 0.00012 22.2 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KNZ81235.1 - 0.00059 20.0 0.1 0.0014 18.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNZ81235.1 - 0.0014 18.7 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KNZ81235.1 - 0.048 13.5 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SET PF00856.23 KNZ81236.1 - 3.3e-06 27.5 0.3 7.5e-06 26.3 0.2 1.8 1 1 0 1 1 1 1 SET domain Pkinase PF00069.20 KNZ81237.1 - 1e-65 221.4 0.0 1.2e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81237.1 - 2e-34 118.8 0.0 2.6e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ81237.1 - 0.037 13.7 0.1 0.16 11.6 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KNZ81237.1 - 0.07 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SNF2_N PF00176.18 KNZ81238.1 - 4.5e-70 235.7 0.2 7.6e-70 235.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KNZ81238.1 - 2.2e-13 49.8 0.0 5.4e-12 45.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KNZ81238.1 - 1.1e-05 25.4 0.0 5.3e-05 23.1 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KNZ81238.1 - 2e-05 24.1 0.0 5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KNZ81238.1 - 0.025 13.4 1.4 1.3 7.8 0.0 2.7 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 DUF2937 PF11157.3 KNZ81238.1 - 0.098 11.9 2.7 7.4 5.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) Mito_carr PF00153.22 KNZ81240.1 - 2.1e-70 232.5 3.0 1.6e-23 82.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TEBP_beta PF07404.6 KNZ81240.1 - 0.15 11.1 0.1 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) FSH1 PF03959.8 KNZ81241.1 - 3.4e-58 196.5 0.0 3.9e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KNZ81241.1 - 4.1e-07 30.1 0.8 0.00034 20.5 0.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ81241.1 - 1.1e-06 28.5 0.0 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KNZ81241.1 - 0.067 12.9 0.0 0.7 9.6 0.0 2.0 2 0 0 2 2 2 0 Cutinase Abhydrolase_2 PF02230.11 KNZ81241.1 - 0.088 12.2 0.0 5.9 6.2 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase HEAT PF02985.17 KNZ81242.1 - 5.5e-22 75.8 19.4 0.00049 19.9 0.0 10.5 10 0 0 10 10 9 5 HEAT repeat HEAT_EZ PF13513.1 KNZ81242.1 - 5.5e-21 74.4 23.3 5.2e-11 42.6 0.0 10.6 9 3 3 12 12 11 3 HEAT-like repeat HEAT_2 PF13646.1 KNZ81242.1 - 1.5e-20 73.2 0.8 2.6e-05 24.3 0.0 7.6 6 3 1 7 7 7 3 HEAT repeats Vac14_Fab1_bd PF12755.2 KNZ81242.1 - 1.9e-09 37.8 0.3 0.0063 16.8 0.0 4.9 4 2 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KNZ81242.1 - 1.9e-08 34.3 0.2 0.064 13.1 0.1 5.9 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 KNZ81242.1 - 4.8e-06 26.4 0.3 0.074 13.0 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Arm PF00514.18 KNZ81242.1 - 4.3e-05 23.1 5.9 3.3 7.6 0.0 6.2 6 0 0 6 6 5 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 KNZ81242.1 - 5e-05 23.1 0.0 0.00073 19.4 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain HTH_Tnp_1 PF01527.15 KNZ81242.1 - 0.024 14.6 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 Transposase CLASP_N PF12348.3 KNZ81242.1 - 0.043 13.1 0.1 20 4.4 0.0 4.0 4 1 1 5 5 5 0 CLASP N terminal Adaptin_N PF01602.15 KNZ81242.1 - 0.096 10.9 1.3 0.39 8.9 0.1 2.5 3 0 0 3 3 3 0 Adaptin N terminal region Lectin_leg-like PF03388.8 KNZ81243.1 - 2.7e-53 180.4 0.6 1.1e-52 178.4 0.4 1.8 1 1 0 1 1 1 1 Legume-like lectin family T2SM_b PF10741.4 KNZ81244.1 - 0.016 14.8 0.3 0.069 12.7 0.1 1.9 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M subtype b Pkinase PF00069.20 KNZ81246.1 - 4.1e-13 49.0 0.0 1.9e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81246.1 - 0.00011 21.3 0.0 0.025 13.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase EcKinase PF02958.15 KNZ81246.1 - 0.11 11.6 0.3 0.24 10.5 0.1 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase Pkinase PF00069.20 KNZ81247.1 - 1.5e-10 40.6 0.0 3.3e-08 32.9 0.0 2.2 1 1 0 2 2 2 2 Protein kinase domain Seadorna_VP7 PF07387.6 KNZ81247.1 - 0.0018 17.1 0.3 0.0029 16.5 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_Tyr PF07714.12 KNZ81247.1 - 0.0022 17.1 0.0 0.13 11.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase EcKinase PF02958.15 KNZ81247.1 - 0.2 10.7 0.3 0.35 9.9 0.2 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Flavokinase PF01687.12 KNZ81248.1 - 6.6e-25 87.4 0.0 9e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase DUF627 PF04781.7 KNZ81248.1 - 0.041 13.4 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Cerato-platanin PF07249.7 KNZ81249.1 - 4.2e-40 136.4 0.3 4.8e-40 136.2 0.2 1.0 1 0 0 1 1 1 1 Cerato-platanin Herpes_Helicase PF02689.9 KNZ81251.1 - 7.5e-06 24.0 0.0 7.9e-06 23.9 0.0 1.0 1 0 0 1 1 1 1 Helicase DNA_repr_REX1B PF14966.1 KNZ81252.1 - 0.067 13.5 0.4 0.094 13.1 0.2 1.3 1 0 0 1 1 1 0 DNA repair REX1-B Pkinase PF00069.20 KNZ81253.1 - 1.3e-12 47.4 0.0 2.3e-10 40.0 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81253.1 - 0.00041 19.5 0.0 0.014 14.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KNZ81253.1 - 0.024 14.3 0.2 4.5 6.9 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KNZ81253.1 - 0.063 12.0 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 NAD_binding_5 PF07994.7 KNZ81254.1 - 5.9e-107 357.5 0.0 7e-107 357.3 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KNZ81254.1 - 5.6e-45 151.7 0.0 1e-44 150.8 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NADH-u_ox-rdase PF10785.4 KNZ81255.1 - 0.99 9.6 3.6 17 5.7 0.5 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit ER_lumen_recept PF00810.13 KNZ81256.1 - 3.1e-57 193.2 6.8 5.6e-57 192.3 4.7 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KNZ81256.1 - 0.00055 19.4 5.1 0.74 9.4 0.1 4.3 3 1 1 4 4 4 2 PQ loop repeat Tox-GHH PF15636.1 KNZ81257.1 - 0.15 11.6 3.9 0.096 12.3 0.3 2.2 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin RNase_H PF00075.19 KNZ81258.1 - 3.1e-11 43.7 0.0 6.9e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 KNZ81258.1 - 2.9e-08 33.3 0.1 5.9e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 KNZ81258.1 - 6.9e-08 32.7 0.2 1.7e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 KNZ81258.1 - 6.5e-07 29.5 0.1 2e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase APH PF01636.18 KNZ81259.1 - 3.5e-07 30.1 0.1 4.3e-05 23.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ81259.1 - 0.044 13.3 0.0 0.056 13.0 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase ATG27 PF09451.5 KNZ81260.1 - 0.16 11.1 2.3 0.2 10.8 1.6 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Cluap1 PF10234.4 KNZ81260.1 - 0.21 10.7 13.2 0.35 10.0 9.2 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 PQQ_2 PF13360.1 KNZ81261.1 - 8.2e-05 22.1 0.0 0.0084 15.5 0.0 2.4 1 1 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 KNZ81261.1 - 0.00064 19.9 0.0 23 5.4 0.0 4.0 4 0 0 4 4 4 2 PQQ-like domain WD40 PF00400.27 KNZ81261.1 - 0.021 14.7 0.0 0.21 11.5 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat BBS1 PF14779.1 KNZ81261.1 - 0.075 11.9 0.1 1.2 8.0 0.0 2.3 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 1 DUF885 PF05960.6 KNZ81262.1 - 0.1 11.7 0.2 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) tRNA_bind PF01588.15 KNZ81265.1 - 3.1e-27 94.2 0.0 5.4e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 KNZ81265.1 - 0.00051 20.4 0.2 0.0013 19.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KNZ81265.1 - 0.0013 18.6 0.2 0.0065 16.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain NARP1 PF12569.3 KNZ81265.1 - 0.077 11.7 1.7 0.12 11.1 1.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GST_C_2 PF13410.1 KNZ81265.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosomal_L6 PF00347.18 KNZ81267.1 - 1.9e-25 89.1 0.0 2.3e-13 50.4 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 DIOX_N PF14226.1 KNZ81268.1 - 1e-23 84.0 0.0 1.6e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KNZ81268.1 - 1.4e-14 54.1 0.0 2.5e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CBFD_NFYB_HMF PF00808.18 KNZ81269.1 - 0.004 17.1 0.0 0.021 14.8 0.0 2.0 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KNZ81269.1 - 0.09 12.5 0.1 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Herpes_LMP1 PF05297.6 KNZ81271.1 - 0.79 8.5 4.8 1.2 7.9 3.3 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1325 PF07039.6 KNZ81272.1 - 2.1e-31 108.2 0.0 3.5e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain MAP7 PF05672.6 KNZ81272.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Translin PF01997.11 KNZ81273.1 - 2.5e-47 161.0 0.3 2.9e-47 160.8 0.2 1.0 1 0 0 1 1 1 1 Translin family DUF2365 PF10157.4 KNZ81273.1 - 0.051 13.4 0.8 2.2 8.1 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) Cu_amine_oxidN1 PF07833.6 KNZ81273.1 - 0.062 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase N-terminal domain SEN1_N PF12726.2 KNZ81274.1 - 9.8e-128 427.2 0.1 1.3e-127 426.8 0.1 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 KNZ81274.1 - 9.9e-63 211.8 0.5 1.8e-62 211.0 0.4 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KNZ81274.1 - 2.2e-60 203.5 0.0 4.9e-60 202.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNZ81274.1 - 1e-12 47.5 0.2 2.9e-12 46.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KNZ81274.1 - 3.8e-08 33.1 0.0 6.2e-05 22.6 0.0 2.8 1 1 0 2 2 2 2 AAA domain DEAD PF00270.24 KNZ81274.1 - 0.00021 20.8 0.2 0.0011 18.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 KNZ81274.1 - 0.00025 20.4 1.1 0.02 14.2 0.4 2.7 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 KNZ81274.1 - 0.00029 20.4 2.2 3.5 7.0 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KNZ81274.1 - 0.00054 19.4 0.2 0.002 17.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KNZ81274.1 - 0.0028 17.5 0.0 0.0072 16.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 KNZ81274.1 - 0.02 13.8 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 KNZ81274.1 - 0.027 14.5 0.4 0.28 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KNZ81274.1 - 0.029 13.8 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 KNZ81274.1 - 0.032 14.2 0.8 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 KNZ81274.1 - 0.038 14.2 1.1 0.16 12.2 0.6 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KNZ81274.1 - 1.4 9.7 3.3 5.2 7.9 1.2 2.9 2 1 0 2 2 1 0 AAA domain IncA PF04156.9 KNZ81274.1 - 1.5 8.3 5.5 3.3 7.2 3.8 1.5 1 0 0 1 1 1 0 IncA protein AAA_23 PF13476.1 KNZ81274.1 - 7 6.9 7.3 46 4.2 5.1 2.2 1 1 0 1 1 1 0 AAA domain Glycos_transf_1 PF00534.15 KNZ81275.1 - 1e-21 77.1 0.0 1.8e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KNZ81275.1 - 2e-08 34.4 0.0 5.8e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KNZ81275.1 - 0.00074 19.7 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Mid2 PF04478.7 KNZ81276.1 - 0.0095 15.3 0.8 0.017 14.5 0.6 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Tmpp129 PF10272.4 KNZ81276.1 - 0.043 12.5 0.0 0.045 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF2852 PF11014.3 KNZ81276.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) SKG6 PF08693.5 KNZ81276.1 - 0.12 11.6 0.2 0.12 11.6 0.2 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain HA2 PF04408.18 KNZ81277.1 - 1.4e-21 76.3 0.0 4.8e-21 74.6 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KNZ81277.1 - 2.8e-19 69.0 0.0 7.2e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KNZ81277.1 - 1.2e-12 47.4 0.0 4.7e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KNZ81277.1 - 1.6e-06 27.7 0.0 4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KNZ81277.1 - 2.3e-05 24.5 0.0 7.1e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KNZ81277.1 - 0.0087 16.4 7.7 0.13 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KNZ81277.1 - 0.014 15.2 1.0 0.19 11.5 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit KaiC PF06745.8 KNZ81277.1 - 0.055 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 KaiC DASH_Dad1 PF08649.5 KNZ81279.1 - 1.5e-14 53.4 0.2 1.8e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 ArsC PF03960.10 KNZ81279.1 - 0.07 13.1 0.0 0.086 12.9 0.0 1.1 1 0 0 1 1 1 0 ArsC family DASH_Dad4 PF08650.5 KNZ81279.1 - 0.084 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 NADPH_Ox PF08414.5 KNZ81279.1 - 0.097 12.7 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase DUF3375 PF11855.3 KNZ81279.1 - 0.12 11.0 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Pkinase PF00069.20 KNZ81280.1 - 6.5e-65 218.8 0.0 1.2e-64 217.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81280.1 - 4e-35 121.1 0.0 6.1e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KNZ81280.1 - 3.5e-20 71.4 27.4 1.1e-10 41.1 6.7 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.11 KNZ81280.1 - 2.4e-19 68.8 15.0 2.2e-15 56.1 4.6 2.4 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.19 KNZ81280.1 - 7.5e-10 39.1 0.9 3.2e-09 37.1 0.1 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KNZ81280.1 - 0.1 11.5 0.0 0.21 10.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Uds1 PF15456.1 KNZ81280.1 - 2.1 8.3 10.3 0.3 11.0 2.2 2.4 2 0 0 2 2 2 0 Up-regulated During Septation Endosulfine PF04667.12 KNZ81282.1 - 1.7e-19 69.5 0.1 2.8e-19 68.8 0.1 1.4 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DNA_pol_E_B PF04042.11 KNZ81283.1 - 4.3e-30 104.5 0.3 6.2e-30 104.0 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 KNZ81283.1 - 4.4e-26 91.9 0.1 1.1e-13 51.2 0.1 2.4 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal DUF4140 PF13600.1 KNZ81284.1 - 0.0081 16.5 4.5 0.0081 16.5 3.1 1.6 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) CENP-F_leu_zip PF10473.4 KNZ81284.1 - 0.0086 15.9 3.8 0.0086 15.9 2.6 2.0 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FbpA PF05833.6 KNZ81284.1 - 0.03 12.8 4.4 0.032 12.7 3.1 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Phage_lysis PF03245.8 KNZ81284.1 - 0.034 14.1 6.7 0.046 13.7 4.6 1.4 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein HEPN PF05168.9 KNZ81284.1 - 0.041 13.7 1.2 0.068 13.0 0.9 1.3 1 0 0 1 1 1 0 HEPN domain Arb1 PF09692.5 KNZ81284.1 - 0.052 12.3 1.4 0.056 12.2 0.4 1.4 1 1 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF3763 PF12592.3 KNZ81284.1 - 0.083 12.5 0.3 0.28 10.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3763) Halogen_Hydrol PF10112.4 KNZ81284.1 - 0.086 12.2 0.2 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Spc7 PF08317.6 KNZ81284.1 - 0.12 10.9 5.6 0.033 12.8 1.6 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein Sin_N PF04801.8 KNZ81284.1 - 0.15 10.9 2.1 0.19 10.5 1.5 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Prp19 PF08606.6 KNZ81284.1 - 0.18 11.5 2.4 0.3 10.8 1.7 1.4 1 0 0 1 1 1 0 Prp19/Pso4-like DUF2884 PF11101.3 KNZ81284.1 - 0.18 11.1 5.3 0.27 10.6 3.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) PEARLI-4 PF05278.7 KNZ81284.1 - 0.3 10.4 11.2 0.015 14.7 3.3 1.8 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) THOC7 PF05615.8 KNZ81284.1 - 0.43 10.8 7.6 0.79 9.9 5.3 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 TPR_MLP1_2 PF07926.7 KNZ81284.1 - 4.5 7.0 11.9 14 5.4 8.2 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Bap31 PF05529.7 KNZ81284.1 - 5.8 6.3 6.0 15 4.9 4.2 1.7 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like M PF02370.11 KNZ81284.1 - 5.8 7.6 9.7 4.4 7.9 2.2 3.0 2 1 1 3 3 2 0 M protein repeat BMFP PF04380.8 KNZ81284.1 - 8 6.6 11.5 22 5.2 0.1 2.5 2 1 0 2 2 2 0 Membrane fusogenic activity IncA PF04156.9 KNZ81284.1 - 9.4 5.7 7.8 15 5.1 5.4 1.5 1 1 0 1 1 1 0 IncA protein TFIIE_beta PF02186.10 KNZ81287.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 TFIIE beta subunit core domain Zn_clus PF00172.13 KNZ81288.1 - 3.8e-07 29.8 11.3 9.8e-07 28.5 7.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_6 PF14835.1 KNZ81289.1 - 0.00013 21.7 2.4 0.00013 21.7 1.6 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 KNZ81289.1 - 0.003 17.5 6.4 0.003 17.5 4.4 4.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KNZ81289.1 - 0.0083 15.7 3.4 0.0083 15.7 2.4 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ81289.1 - 0.018 14.7 6.0 0.018 14.7 4.1 3.9 4 0 0 4 4 4 0 zinc-RING finger domain Kelch_4 PF13418.1 KNZ81290.1 - 6.4e-20 70.6 9.6 1.5e-05 24.6 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 KNZ81290.1 - 1.5e-16 59.6 2.3 7.5e-06 25.4 0.1 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 KNZ81290.1 - 3.2e-16 58.7 7.3 0.00028 20.9 0.0 5.3 5 0 0 5 5 4 4 Kelch motif Kelch_3 PF13415.1 KNZ81290.1 - 2.9e-15 55.9 8.1 1.3e-05 25.1 0.0 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KNZ81290.1 - 2e-12 46.7 0.5 0.00029 20.7 0.1 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 KNZ81290.1 - 3.6e-10 39.1 2.8 0.00071 19.2 0.0 4.6 5 0 0 5 5 5 2 Kelch motif SprA-related PF12118.3 KNZ81290.1 - 0.0088 15.4 8.9 0.013 14.7 6.2 1.2 1 0 0 1 1 1 1 SprA-related family NAM-associated PF14303.1 KNZ81290.1 - 0.052 13.8 21.4 0.1 12.9 14.9 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Rax2 PF12768.2 KNZ81290.1 - 0.23 10.6 0.1 4.4 6.4 0.0 2.6 2 1 1 3 3 3 0 Cortical protein marker for cell polarity DUF1510 PF07423.6 KNZ81290.1 - 2.5 7.4 19.8 3.9 6.7 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 KNZ81290.1 - 4 5.7 31.0 6.5 5.1 21.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pyridox_oxidase PF01243.15 KNZ81291.1 - 1.4e-22 79.5 0.0 2.6e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 KNZ81291.1 - 3.3e-19 68.0 1.7 7.3e-19 66.9 1.2 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.2 KNZ81291.1 - 4.2e-06 26.9 0.0 6.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Glycolytic PF00274.14 KNZ81292.1 - 1.6e-66 224.1 0.0 2.8e-41 141.0 0.0 2.1 1 1 1 2 2 2 2 Fructose-bisphosphate aldolase class-I DUF1996 PF09362.5 KNZ81293.1 - 9.7e-73 244.6 1.4 1.2e-72 244.3 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Glyco_hydro_cc PF11790.3 KNZ81294.1 - 6.2e-52 176.3 0.2 7.1e-52 176.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Inhibitor_I42 PF09394.5 KNZ81294.1 - 0.11 12.7 0.1 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Chagasin family peptidase inhibitor I42 zf-CCHC PF00098.18 KNZ81296.1 - 0.082 12.8 0.5 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle RasGEF PF00617.14 KNZ81297.1 - 4.7e-55 186.2 0.8 4.7e-55 186.2 0.6 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 KNZ81297.1 - 2.4e-20 72.5 0.7 1.5e-19 70.0 0.0 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 KNZ81297.1 - 8.3e-15 53.9 0.4 2.7e-14 52.2 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KNZ81297.1 - 2.5e-14 52.4 0.1 6.4e-14 51.1 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KNZ81297.1 - 5.3e-13 48.3 0.8 3.1e-12 45.8 0.3 2.3 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.21 KNZ81297.1 - 0.14 12.0 2.3 0.69 9.8 0.1 2.7 2 0 0 2 2 2 0 WW domain COG2 PF06148.6 KNZ81297.1 - 0.82 9.5 5.3 0.6 9.9 0.7 2.9 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 RasGEF PF00617.14 KNZ81298.1 - 8.5e-58 195.1 0.4 1.6e-57 194.2 0.3 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KNZ81298.1 - 2.7e-18 65.9 0.1 8.7e-18 64.3 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KNZ81298.1 - 5.7e-16 57.6 0.1 1.2e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KNZ81298.1 - 2e-13 49.6 0.3 4.3e-13 48.6 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KNZ81298.1 - 4.4e-13 48.4 0.0 7.8e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain GTP_EFTU PF00009.22 KNZ81299.1 - 6.8e-53 178.8 0.0 1.4e-52 177.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KNZ81299.1 - 2.6e-15 56.0 0.0 7.3e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KNZ81299.1 - 1.8e-09 37.3 0.0 5.3e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KNZ81299.1 - 4.4e-06 26.7 0.0 1.2e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KNZ81299.1 - 6e-05 22.9 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.13 KNZ81299.1 - 0.0038 16.7 0.0 0.097 12.2 0.0 3.0 2 1 0 2 2 2 1 Elongation factor G, domain IV Septin PF00735.13 KNZ81299.1 - 0.09 11.7 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin SRPRB PF09439.5 KNZ81299.1 - 0.098 11.8 0.1 0.49 9.6 0.1 2.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit CwfJ_C_1 PF04677.10 KNZ81300.1 - 1e-31 109.0 0.0 1.6e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KNZ81300.1 - 3.5e-25 88.3 0.1 1.1e-22 80.3 0.0 2.7 2 0 0 2 2 2 2 Protein similar to CwfJ C-terminus 2 p450 PF00067.17 KNZ81301.1 - 2.6e-63 214.1 0.0 3.3e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HpcH_HpaI PF03328.9 KNZ81302.1 - 1.7e-39 134.9 0.0 2.7e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KNZ81302.1 - 7.7e-12 44.6 0.0 1.8e-06 27.0 0.0 2.1 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold OB_NTP_bind PF07717.11 KNZ81303.1 - 1.2e-28 99.1 0.2 3.3e-28 97.7 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KNZ81303.1 - 2.9e-27 94.6 0.0 4.5e-26 90.8 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KNZ81303.1 - 5.9e-14 51.6 0.0 1.4e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KNZ81303.1 - 5.5e-07 29.2 0.1 2.6e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KNZ81303.1 - 4.2e-05 23.7 0.0 0.00017 21.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KNZ81303.1 - 0.0023 16.8 0.0 0.0048 15.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Herpes_ori_bp PF02399.10 KNZ81303.1 - 0.04 11.8 0.0 0.067 11.1 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein AAA_19 PF13245.1 KNZ81303.1 - 0.08 12.7 3.4 0.14 11.9 0.1 2.7 3 0 0 3 3 3 0 Part of AAA domain ResIII PF04851.10 KNZ81303.1 - 0.089 12.6 5.6 0.2 11.4 0.1 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit adh_short PF00106.20 KNZ81304.1 - 1.1e-18 67.7 0.0 1.7e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ81304.1 - 3.8e-05 23.4 0.0 7.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KNZ81304.1 - 0.00022 20.9 0.3 0.00047 19.8 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KNZ81304.1 - 0.00032 20.2 0.0 0.00042 19.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KNZ81304.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KNZ81304.1 - 0.0028 17.6 0.3 0.005 16.8 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KNZ81304.1 - 0.065 12.4 0.1 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family RVP_2 PF08284.6 KNZ81306.1 - 8.8e-06 25.6 0.4 0.0054 16.6 0.1 2.4 1 1 1 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KNZ81306.1 - 0.07 12.9 0.1 18 5.2 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease CoA_transf_3 PF02515.12 KNZ81307.1 - 3.1e-65 218.9 0.0 4.2e-65 218.5 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III CoA_transf_3 PF02515.12 KNZ81310.1 - 1.6e-66 223.2 0.0 2.1e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Helicase_C_2 PF13307.1 KNZ81311.1 - 1.4e-53 181.3 0.0 5e-53 179.4 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 KNZ81311.1 - 9.1e-41 139.1 0.0 4.5e-39 133.6 0.0 2.6 1 1 0 1 1 1 1 DEAD_2 PhoH PF02562.11 KNZ81311.1 - 4.6e-05 22.7 0.1 0.069 12.3 0.0 2.7 3 0 0 3 3 3 2 PhoH-like protein DEAD PF00270.24 KNZ81311.1 - 0.00092 18.7 0.0 0.026 14.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KNZ81311.1 - 0.0039 17.3 0.0 4.4 7.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 KNZ81311.1 - 0.0064 16.3 0.3 0.39 10.5 0.2 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KNZ81311.1 - 0.029 14.1 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 KNZ81311.1 - 0.049 12.5 0.0 0.14 11.0 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 KNZ81311.1 - 0.074 13.3 1.1 0.12 12.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 KNZ81311.1 - 0.17 10.6 1.4 50 2.5 0.0 3.2 2 1 1 3 3 3 0 SNF2 family N-terminal domain AAA_11 PF13086.1 KNZ81311.1 - 0.23 10.9 2.7 0.15 11.6 0.3 1.9 2 0 0 2 2 2 0 AAA domain DUF563 PF04577.9 KNZ81312.1 - 7.9e-06 25.9 0.3 2.3e-05 24.3 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF563) zf-CCHC_3 PF13917.1 KNZ81314.1 - 3.6e-16 58.5 0.3 3.6e-16 58.5 0.2 1.8 2 0 0 2 2 2 1 Zinc knuckle ChaC PF04752.7 KNZ81314.1 - 0.051 13.5 0.0 0.063 13.2 0.0 1.1 1 0 0 1 1 1 0 ChaC-like protein TFIIF_alpha PF05793.7 KNZ81314.1 - 0.051 11.9 8.9 0.06 11.7 6.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4196 PF13846.1 KNZ81314.1 - 0.075 13.3 5.5 0.13 12.5 3.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4196) Atrophin-1 PF03154.10 KNZ81314.1 - 0.12 10.5 6.1 0.13 10.3 4.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family ATP-synt_C PF00137.16 KNZ81315.1 - 9.9e-25 86.2 32.3 3e-17 62.2 5.4 2.5 3 0 0 3 3 3 2 ATP synthase subunit C Peptidase_M20 PF01546.23 KNZ81316.1 - 1.8e-26 92.8 0.0 3.5e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KNZ81316.1 - 4.1e-24 83.5 17.9 1.2e-07 31.2 0.1 8.4 8 1 0 8 8 8 6 WD domain, G-beta repeat M20_dimer PF07687.9 KNZ81316.1 - 2.3e-12 46.6 0.0 4.5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Spt5-NGN PF03439.8 KNZ81318.1 - 2.5e-22 78.3 0.0 5.9e-22 77.2 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KNZ81318.1 - 1e-16 59.8 22.1 0.0034 17.0 0.7 7.2 7 0 0 7 7 7 4 KOW motif CTD PF12815.2 KNZ81318.1 - 5.6e-11 42.9 60.4 6.1e-06 26.6 37.2 3.5 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 KNZ81318.1 - 1e-08 35.7 12.3 1e-08 35.7 8.6 2.9 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal YajC PF02699.10 KNZ81318.1 - 0.21 11.2 7.2 0.4 10.4 0.6 3.3 2 1 1 3 3 3 0 Preprotein translocase subunit PGA2 PF07543.7 KNZ81318.1 - 0.97 9.2 19.0 2.8 7.7 13.2 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 Protocadherin PF08374.6 KNZ81318.1 - 2.7 7.5 5.8 5 6.6 4.0 1.3 1 0 0 1 1 1 0 Protocadherin VEFS-Box PF09733.4 KNZ81318.1 - 5.3 6.7 16.0 0.37 10.4 7.3 1.8 1 1 1 2 2 2 0 VEFS-Box of polycomb protein F-box-like PF12937.2 KNZ81319.1 - 1e-05 25.1 2.2 1.3e-05 24.8 0.1 2.3 2 0 0 2 2 2 1 F-box-like DJ-1_PfpI PF01965.19 KNZ81320.1 - 3.3e-22 78.5 0.0 4.2e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KNZ81320.1 - 8.6e-10 38.1 0.0 1.2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 KNZ81320.1 - 0.062 12.8 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Repressor_Mnt PF11423.3 KNZ81320.1 - 0.068 12.4 0.0 3.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Regulatory protein Mnt BTB PF00651.26 KNZ81321.1 - 0.033 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain zf-RVT PF13966.1 KNZ81323.1 - 0.03 14.6 4.3 0.18 12.1 1.4 2.3 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase RVT_1 PF00078.22 KNZ81325.1 - 0.008 15.5 0.0 0.0084 15.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YMF19 PF02326.10 KNZ81326.1 - 0.35 11.4 0.1 0.35 11.4 0.1 2.9 3 0 0 3 3 3 0 Plant ATP synthase F0 Pro_isomerase PF00160.16 KNZ81327.1 - 6e-42 143.4 0.1 9.4e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KNZ81327.1 - 1.8e-10 40.2 3.7 2.7e-06 26.9 0.1 2.5 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 KNZ81327.1 - 2.5e-07 30.1 3.0 0.027 14.3 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ81327.1 - 4.7e-06 25.9 3.0 0.063 12.9 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ81327.1 - 0.002 18.0 0.2 2.3 8.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 KNZ81327.1 - 0.018 14.8 1.9 0.66 9.8 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 KNZ81327.1 - 0.046 14.3 2.7 0.99 10.1 0.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Exo_endo_phos PF03372.18 KNZ81328.1 - 1.6e-14 54.4 0.0 2.4e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 KNZ81328.1 - 0.0022 17.6 0.0 0.28 10.7 0.0 2.4 1 1 1 2 2 2 2 RhoGAP domain UBN2_3 PF14244.1 KNZ81329.1 - 0.00028 20.4 0.5 0.0035 16.8 0.0 2.5 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type HABP4_PAI-RBP1 PF04774.10 KNZ81330.1 - 2.9e-05 24.5 2.9 4.2e-05 23.9 2.0 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family RVT_1 PF00078.22 KNZ81330.1 - 0.042 13.2 0.1 0.067 12.5 0.0 1.4 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.11 KNZ81331.1 - 6.1e-41 140.2 42.3 6.1e-41 140.2 29.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KNZ81331.1 - 1.7e-08 33.4 38.7 2.6e-08 32.8 26.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KNZ81331.1 - 3.9e-08 31.9 1.4 3.9e-08 31.9 1.0 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.23 KNZ81332.1 - 4.4e-31 107.7 0.0 3.5e-30 104.7 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KNZ81332.1 - 9.5e-26 90.2 0.0 1.5e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KNZ81332.1 - 4.2e-09 36.1 0.0 6.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KNZ81332.1 - 6.8e-05 22.9 0.0 0.0052 16.8 0.0 2.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KNZ81332.1 - 0.13 12.1 0.0 0.77 9.6 0.0 2.2 1 1 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KNZ81332.1 - 0.15 10.9 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KNZ81332.1 - 0.27 9.9 0.0 0.48 9.0 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 KNZ81333.1 - 1.1e-16 60.4 55.6 8.7e-14 50.9 26.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily BatA PF07584.6 KNZ81333.1 - 0.0052 16.9 1.1 0.38 10.9 0.0 2.6 2 0 0 2 2 2 2 Aerotolerance regulator N-terminal TFIIS_C PF01096.13 KNZ81334.1 - 1.8e-08 33.8 6.7 1.3e-06 27.8 1.4 2.4 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KNZ81334.1 - 2.3e-07 30.3 4.2 2.3e-07 30.3 2.9 2.7 2 1 1 3 3 3 1 RNA polymerases M/15 Kd subunit Rep_fac-A_C PF08646.5 KNZ81334.1 - 0.12 12.0 2.8 0.58 9.8 0.0 2.0 2 0 0 2 2 2 0 Replication factor-A C terminal domain zf-C2H2 PF00096.21 KNZ81334.1 - 0.16 12.3 4.5 0.22 11.9 0.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3268 PF11672.3 KNZ81334.1 - 0.27 11.3 1.8 4.2 7.4 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3268) C1_4 PF07975.7 KNZ81334.1 - 0.27 11.2 8.2 1.7 8.7 0.6 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain zf-UBR PF02207.15 KNZ81334.1 - 1.2 8.9 5.0 5.6 6.7 0.8 2.2 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) zf-C2H2_4 PF13894.1 KNZ81334.1 - 2.7 8.5 4.8 3.8 8.0 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Hydrophobin PF01185.13 KNZ81335.1 - 3.2e-16 59.5 12.8 4.4e-16 59.1 8.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.13 KNZ81335.1 - 0.019 15.0 0.5 0.019 15.0 0.3 2.2 2 0 0 2 2 2 0 Granulin MF_alpha_N PF05436.6 KNZ81335.1 - 0.16 11.6 0.8 0.6 9.8 0.0 2.0 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus YjbE PF11106.3 KNZ81335.1 - 0.24 11.3 0.2 0.24 11.3 0.1 2.4 2 1 0 2 2 2 0 Exopolysaccharide production protein YjbE Ribosomal_L27e PF01777.13 KNZ81336.1 - 3.7e-35 119.9 1.3 5.4e-35 119.3 0.9 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KNZ81336.1 - 0.0084 15.8 0.9 0.024 14.3 0.6 1.9 1 0 0 1 1 1 1 KOW motif Mito_carr PF00153.22 KNZ81337.1 - 3.9e-13 48.9 0.0 5.8e-06 25.9 0.0 3.0 2 1 0 2 2 2 2 Mitochondrial carrier protein 60KD_IMP PF02096.15 KNZ81337.1 - 0.01 15.4 0.2 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein RRM_6 PF14259.1 KNZ81338.1 - 0.087 12.8 0.0 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.2 KNZ81338.1 - 0.17 11.5 4.4 4.5 7.0 2.5 2.8 2 1 0 2 2 2 0 F-box-like Vps39_1 PF10366.4 KNZ81339.1 - 1.7e-08 34.4 0.9 6.8e-08 32.4 0.1 2.5 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KNZ81339.1 - 4.2e-08 33.3 0.0 1.7e-07 31.3 0.0 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 KNZ81339.1 - 2.1e-05 24.1 0.0 0.00011 21.8 0.0 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS Ank_4 PF13637.1 KNZ81340.1 - 1.6e-18 66.6 0.1 5.5e-07 29.9 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KNZ81340.1 - 3.8e-18 65.6 0.0 1e-08 35.3 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KNZ81340.1 - 1.1e-16 60.4 0.4 5.9e-06 26.3 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KNZ81340.1 - 3.7e-16 58.0 0.3 0.00024 20.7 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 KNZ81340.1 - 1e-13 50.0 0.2 0.016 15.4 0.0 5.4 5 1 1 6 6 6 3 Ankyrin repeat NT-C2 PF10358.4 KNZ81341.1 - 6.4e-19 67.8 0.0 7.5e-18 64.3 0.0 2.2 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Myb_Cef PF11831.3 KNZ81343.1 - 1.7e-55 187.7 0.0 1.7e-55 187.7 0.0 3.7 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KNZ81343.1 - 1.1e-19 70.2 9.7 8e-11 41.8 0.4 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KNZ81343.1 - 8.4e-17 61.0 7.6 3e-12 46.4 2.2 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain LsmAD PF06741.8 KNZ81343.1 - 1.6 8.8 0.0 1.6 8.8 0.0 3.5 4 0 0 4 4 4 0 LsmAD domain DUF1690 PF07956.6 KNZ81344.1 - 3e-13 49.9 1.2 4.4e-13 49.4 0.8 1.2 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Allexi_40kDa PF05549.6 KNZ81345.1 - 0.045 13.0 0.1 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein AATF-Che1 PF13339.1 KNZ81345.1 - 0.087 12.9 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Sel1 PF08238.7 KNZ81346.1 - 1.2e-45 152.9 21.5 2.3e-08 34.4 0.0 7.8 7 0 0 7 7 7 7 Sel1 repeat PITH PF06201.8 KNZ81346.1 - 4.9e-40 136.7 0.4 7.8e-40 136.1 0.2 1.3 1 0 0 1 1 1 1 PITH domain JmjC PF02373.17 KNZ81346.1 - 2.3e-08 34.2 0.9 2e-07 31.2 0.6 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 KNZ81346.1 - 0.00017 21.2 7.4 0.0003 20.4 5.1 1.4 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.1 KNZ81346.1 - 0.0026 17.2 0.3 0.0026 17.2 0.2 1.8 2 0 0 2 2 2 1 Cupin-like domain TPR_14 PF13428.1 KNZ81346.1 - 0.0068 16.9 9.5 0.6 10.8 0.7 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat PHD_2 PF13831.1 KNZ81346.1 - 0.045 13.0 9.9 0.016 14.5 4.7 1.9 2 0 0 2 2 2 0 PHD-finger GPI PF06560.6 KNZ81346.1 - 0.049 12.6 0.0 0.093 11.7 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Prok-RING_1 PF14446.1 KNZ81346.1 - 0.079 12.7 2.1 0.18 11.5 1.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FBA_1 PF07734.8 KNZ81347.1 - 0.046 13.4 0.0 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 F-box associated UBN2_2 PF14227.1 KNZ81347.1 - 0.074 12.6 0.3 0.091 12.3 0.2 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-rbx1 PF12678.2 KNZ81349.1 - 0.028 14.5 5.2 0.048 13.7 3.6 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 KNZ81349.1 - 4.3 7.1 7.0 12 5.7 0.2 2.6 2 1 1 3 3 3 0 zf-RING of BARD1-type protein CPSase_L_D2 PF02786.12 KNZ81351.1 - 2.5e-05 23.6 0.2 4e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D2 PF02786.12 KNZ81354.1 - 5.4e-07 29.1 0.1 6.2e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 KNZ81354.1 - 0.079 12.4 0.0 0.082 12.3 0.0 1.1 1 0 0 1 1 1 0 RimK-like ATP-grasp domain zf-CCHC PF00098.18 KNZ81355.1 - 0.029 14.3 5.9 0.059 13.3 4.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 KNZ81355.1 - 0.052 13.2 1.5 0.12 12.1 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle PhoQ_Sensor PF08918.5 KNZ81356.1 - 0.18 11.3 1.0 0.4 10.1 0.7 1.5 1 0 0 1 1 1 0 PhoQ Sensor UbiA PF01040.13 KNZ81357.1 - 3.8e-22 78.7 9.4 4.6e-22 78.4 6.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Toxin_37 PF11415.3 KNZ81357.1 - 0.028 14.0 0.5 0.26 10.9 0.4 2.5 2 0 0 2 2 2 0 Antifungal peptide termicin CopD PF05425.8 KNZ81357.1 - 2.8 8.1 7.3 6.6 7.0 0.0 3.0 3 1 1 4 4 4 0 Copper resistance protein D DUF2293 PF10056.4 KNZ81358.1 - 0.033 14.1 3.9 0.035 14.0 0.1 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2293) Cep57_CLD_2 PF14197.1 KNZ81358.1 - 0.1 12.5 0.5 0.23 11.4 0.3 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 BCAS2 PF05700.6 KNZ81358.1 - 0.77 9.1 4.7 5.5 6.3 3.2 2.0 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) AcylCoA_dehyd_C PF12186.3 KNZ81359.1 - 0.057 13.2 0.5 0.057 13.2 0.4 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal Baculo_PEP_C PF04513.7 KNZ81359.1 - 0.1 12.4 1.3 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AKAP95 PF04988.7 KNZ81359.1 - 0.11 12.2 2.2 0.51 10.0 0.1 2.3 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Abhydrolase_6 PF12697.2 KNZ81360.1 - 1.3e-21 77.5 0.0 1.6e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ81360.1 - 2.2e-10 40.5 0.0 3.7e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ81360.1 - 2.3e-08 33.9 0.0 0.00032 20.4 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ81360.1 - 0.00063 19.0 0.0 0.00093 18.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KNZ81360.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family APH PF01636.18 KNZ81361.1 - 2e-12 47.4 0.1 3.7e-12 46.4 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KNZ81361.1 - 1.2e-05 24.9 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KNZ81361.1 - 0.0053 15.9 0.0 0.5 9.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.17 KNZ81361.1 - 0.081 12.2 0.1 0.61 9.4 0.0 2.1 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.15 KNZ81361.1 - 0.17 11.0 0.3 3.8 6.5 0.0 2.0 1 1 0 2 2 2 0 Ecdysteroid kinase Helitron_like_N PF14214.1 KNZ81362.1 - 5.4e-22 78.4 0.0 7.1e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Gemini_AL1 PF00799.15 KNZ81362.1 - 0.045 13.6 0.3 0.062 13.1 0.2 1.3 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain PIF1 PF05970.9 KNZ81363.1 - 8.2e-07 28.2 0.1 1.4e-06 27.5 0.0 1.4 2 0 0 2 2 2 1 PIF1-like helicase ResIII PF04851.10 KNZ81363.1 - 0.0065 16.3 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Herpes_Helicase PF02689.9 KNZ81364.1 - 1.6e-07 29.4 0.0 1.7e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 Helicase Chromo PF00385.19 KNZ81369.1 - 8.1e-19 67.0 0.1 9.7e-19 66.8 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KNZ81369.1 - 0.0043 16.7 1.3 0.0055 16.3 0.9 1.2 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Mtf2_C PF14061.1 KNZ81369.1 - 0.048 13.5 0.1 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Chromo PF00385.19 KNZ81371.1 - 8.1e-10 38.2 0.1 9.5e-10 38.0 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KNZ81371.1 - 0.08 12.6 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF4066 PF13278.1 KNZ81372.1 - 5.9e-06 25.6 0.0 6.9e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase Mt_ATP-synt_B PF05405.9 KNZ81374.1 - 1.4e-41 141.7 11.3 1.6e-41 141.5 7.8 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2909 PF11137.3 KNZ81374.1 - 0.024 14.3 0.2 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) DUF1253 PF06862.7 KNZ81374.1 - 0.07 11.5 2.4 0.088 11.1 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) DUF2526 PF10735.4 KNZ81374.1 - 0.21 11.5 1.9 0.62 10.0 1.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2526) DUF4207 PF13904.1 KNZ81374.1 - 2.2 7.5 7.2 5.1 6.4 5.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) Glyco_hydro_61 PF03443.9 KNZ81375.1 - 7.2e-38 130.5 0.1 1.2e-37 129.8 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Host_attach PF10116.4 KNZ81376.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein required for attachment to host cells F-box-like PF12937.2 KNZ81377.1 - 2.4e-06 27.1 0.8 5.5e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 F-box-like Peroxin-3 PF04882.7 KNZ81378.1 - 2e-86 290.3 0.2 3.9e-86 289.4 0.1 1.4 1 1 0 1 1 1 1 Peroxin-3 Chromo PF00385.19 KNZ81380.1 - 0.38 10.4 1.8 0.66 9.6 1.3 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain UBN2_2 PF14227.1 KNZ81382.1 - 0.00018 21.0 0.3 0.00043 19.8 0.0 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KNZ81382.1 - 0.0046 16.5 0.1 0.0079 15.7 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Glyoxalase_4 PF13669.1 KNZ81386.1 - 0.062 13.3 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF4557 PF15101.1 KNZ81388.1 - 0.0004 20.3 0.0 0.00098 19.0 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4557) UBN2_2 PF14227.1 KNZ81391.1 - 3e-06 26.7 0.2 6.4e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ81391.1 - 3.6e-05 23.5 0.2 7.4e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KNZ81391.1 - 0.0059 16.1 4.2 0.0059 16.1 2.9 2.9 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4285 PF14113.1 KNZ81391.1 - 0.013 15.5 2.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4285) DUF1054 PF06335.7 KNZ81391.1 - 0.086 12.5 3.0 0.17 11.5 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1054) DUF4219 PF13961.1 KNZ81391.1 - 0.33 10.4 2.0 0.86 9.0 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Aldedh PF00171.17 KNZ81393.1 - 2.5e-121 405.2 0.0 2.9e-121 405.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KNZ81393.1 - 1.9e-08 33.4 0.0 2.8e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Cellulase PF00150.13 KNZ81394.1 - 3.7e-14 52.6 5.8 7.8e-14 51.5 3.9 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 KNZ81394.1 - 0.0013 17.9 1.0 0.25 10.4 0.7 2.4 1 1 0 1 1 1 1 Beta-galactosidase Sucrose_synth PF00862.14 KNZ81394.1 - 0.079 10.9 0.0 0.38 8.6 0.0 1.8 2 0 0 2 2 2 0 Sucrose synthase Mito_carr PF00153.22 KNZ81395.1 - 5.5e-54 179.8 0.3 6.9e-18 64.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Proteasome PF00227.21 KNZ81396.1 - 1.4e-47 161.4 0.1 1.7e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KNZ81396.1 - 3.9e-09 35.6 0.0 7.7e-09 34.6 0.0 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Syntaxin PF00804.20 KNZ81397.1 - 0.014 15.5 80.9 0.32 11.1 6.6 6.2 5 1 0 5 5 5 0 Syntaxin Tropomyosin_1 PF12718.2 KNZ81397.1 - 0.81 9.5 94.3 0.92 9.3 7.7 5.6 4 1 1 5 5 5 0 Tropomyosin like RRF PF01765.14 KNZ81398.1 - 5.2e-30 104.0 1.0 9.3e-30 103.2 0.7 1.3 1 1 0 1 1 1 1 Ribosome recycling factor Sas10 PF09368.5 KNZ81398.1 - 0.043 13.9 1.0 0.08 13.1 0.7 1.4 1 0 0 1 1 1 0 Sas10 C-terminal domain MatE PF01554.13 KNZ81399.1 - 2.4e-50 170.3 32.2 5.3e-27 94.4 7.9 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KNZ81399.1 - 1.1e-06 28.5 9.6 1.1e-06 28.5 6.6 3.8 3 3 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain MatE PF01554.13 KNZ81400.1 - 8.4e-55 184.8 28.8 3.7e-31 107.9 7.3 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KNZ81400.1 - 3.8e-08 33.2 9.9 3.8e-08 33.2 6.8 3.9 3 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain GST_N_3 PF13417.1 KNZ81401.1 - 1e-09 38.4 0.0 2.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KNZ81401.1 - 0.0001 22.2 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KNZ81401.1 - 0.00054 20.0 0.0 0.0014 18.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KNZ81401.1 - 0.0006 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Alpha-L-AF_C PF06964.7 KNZ81402.1 - 4.5e-40 137.2 0.4 9e-40 136.3 0.3 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Gmad2 PF10648.4 KNZ81402.1 - 7e-05 22.9 0.1 0.00038 20.5 0.1 2.3 1 0 0 1 1 1 1 Immunoglobulin-like domain of bacterial spore germination CBM_4_9 PF02018.12 KNZ81402.1 - 0.51 10.3 6.8 0.2 11.6 0.4 2.8 2 1 0 2 2 2 0 Carbohydrate binding domain Metallophos_2 PF12850.2 KNZ81403.1 - 5.6e-06 26.2 0.0 1.2e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KNZ81403.1 - 5.7e-06 25.8 0.4 1.3e-05 24.7 0.3 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_16 PF00722.16 KNZ81404.1 - 3.5e-06 26.4 0.0 8.5e-06 25.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 RNase_H PF00075.19 KNZ81408.1 - 8.6e-19 68.1 0.2 1.9e-18 67.0 0.0 1.6 2 0 0 2 2 2 1 RNase H Methyltransf_16 PF10294.4 KNZ81410.1 - 1.2e-05 24.8 0.0 0.026 13.9 0.0 2.4 2 1 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 KNZ81410.1 - 0.0081 15.8 0.0 0.024 14.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ81410.1 - 0.017 14.7 0.0 4.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain S1-P1_nuclease PF02265.11 KNZ81411.1 - 3.3e-45 154.6 0.0 3.1e-44 151.4 0.0 2.1 1 1 0 1 1 1 1 S1/P1 Nuclease MFS_1 PF07690.11 KNZ81414.1 - 3.4e-24 85.2 32.8 5.6e-24 84.5 22.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KNZ81414.1 - 0.0053 15.0 5.9 0.008 14.4 4.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KNZ81415.1 - 4.8e-19 68.2 26.1 7.3e-19 67.6 18.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TctB PF07331.6 KNZ81415.1 - 4.4 6.9 18.7 0.31 10.6 3.5 3.4 2 2 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF3792 PF12670.2 KNZ81415.1 - 7.4 6.4 13.3 0.05 13.4 1.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3792) Aldedh PF00171.17 KNZ81416.1 - 3.9e-109 365.0 0.4 5.5e-109 364.5 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KNZ81416.1 - 1.6e-05 23.8 0.0 2.9e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) LPP PF04728.8 KNZ81416.1 - 0.0037 17.0 0.2 0.0075 16.0 0.1 1.4 1 0 0 1 1 1 1 Lipoprotein leucine-zipper Sin3_corepress PF08295.7 KNZ81417.1 - 1.2e-34 118.0 0.1 4e-34 116.4 0.1 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 KNZ81417.1 - 4.5e-31 106.2 3.9 9.8e-14 50.7 0.0 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Pkinase PF00069.20 KNZ81418.1 - 2.4e-09 36.7 0.0 4.9e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81418.1 - 0.055 12.5 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KNZ81419.1 - 5.7e-10 38.7 0.0 1.1e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81419.1 - 0.061 12.3 0.0 0.12 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase PCNA_N PF00705.13 KNZ81421.1 - 3.2e-52 175.3 3.1 3.2e-52 175.3 2.1 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KNZ81421.1 - 3.5e-40 136.8 0.0 1.5e-18 66.9 0.0 2.7 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KNZ81421.1 - 9.1e-07 28.2 0.0 3.9e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Rad9 Hus1 PF04005.7 KNZ81421.1 - 0.014 14.3 4.6 1.4 7.7 0.0 3.5 2 1 1 3 3 3 0 Hus1-like protein Daxx PF03344.10 KNZ81421.1 - 0.12 10.8 26.6 0.16 10.4 18.4 1.1 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 KNZ81421.1 - 1.1 8.2 42.3 1.9 7.4 29.3 1.2 1 0 0 1 1 1 0 BUD22 DAO PF01266.19 KNZ81422.1 - 2.2e-45 155.1 0.1 2.6e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KNZ81422.1 - 7.1e-07 29.4 0.0 0.0046 17.0 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ81422.1 - 1.1e-05 25.4 0.1 3.1e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KNZ81422.1 - 0.0011 18.7 0.1 0.0054 16.5 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 KNZ81422.1 - 0.0021 17.1 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KNZ81422.1 - 0.0029 17.9 1.0 0.23 11.9 0.1 3.3 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KNZ81422.1 - 0.0031 16.6 0.0 0.79 8.7 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 KNZ81422.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF371 PF04027.8 KNZ81422.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF371) FAD_oxidored PF12831.2 KNZ81422.1 - 0.13 11.3 0.2 0.23 10.4 0.2 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pkinase PF00069.20 KNZ81423.1 - 5.9e-12 45.2 0.0 1.4e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81423.1 - 0.016 14.3 0.0 0.031 13.3 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase AAA PF00004.24 KNZ81427.1 - 1e-60 203.6 0.0 1.3e-45 154.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KNZ81427.1 - 4.9e-07 30.5 0.0 0.0048 17.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KNZ81427.1 - 8.9e-07 29.0 1.1 0.008 16.1 0.1 3.8 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KNZ81427.1 - 1.3e-06 27.6 0.0 0.0037 16.3 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KNZ81427.1 - 3.2e-05 23.4 0.6 0.028 13.8 0.1 2.8 2 1 1 3 3 2 2 AAA domain AAA_5 PF07728.9 KNZ81427.1 - 5e-05 23.0 0.1 0.011 15.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KNZ81427.1 - 0.0002 21.4 0.2 0.0041 17.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 KNZ81427.1 - 0.00046 19.0 0.0 0.023 13.4 0.0 2.7 3 0 0 3 3 3 1 TIP49 C-terminus AAA_14 PF13173.1 KNZ81427.1 - 0.00053 19.8 0.0 0.041 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KNZ81427.1 - 0.00069 19.3 0.0 0.005 16.5 0.0 2.4 3 0 0 3 3 2 1 Part of AAA domain IstB_IS21 PF01695.12 KNZ81427.1 - 0.00077 18.9 0.1 0.0024 17.3 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein KaiC PF06745.8 KNZ81427.1 - 0.0023 17.0 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 KaiC Sigma54_activat PF00158.21 KNZ81427.1 - 0.0028 17.1 0.0 1.2 8.5 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_2 PF07724.9 KNZ81427.1 - 0.0032 17.4 0.0 0.0086 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KNZ81427.1 - 0.0033 17.5 0.0 0.066 13.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 KNZ81427.1 - 0.0048 17.1 0.0 0.12 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 KNZ81427.1 - 0.0063 15.4 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.16 KNZ81427.1 - 0.009 15.1 0.1 0.035 13.2 0.1 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KNZ81427.1 - 0.0092 15.8 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.5 KNZ81427.1 - 0.013 15.3 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain NACHT PF05729.7 KNZ81427.1 - 0.027 14.1 0.3 2.3 7.8 0.0 3.2 4 0 0 4 4 3 0 NACHT domain PhoH PF02562.11 KNZ81427.1 - 0.028 13.6 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 KNZ81427.1 - 0.034 13.7 0.2 0.079 12.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KNZ81427.1 - 0.038 13.6 0.0 0.39 10.3 0.0 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KNZ81427.1 - 0.038 13.9 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.8 KNZ81427.1 - 0.042 12.7 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SKI PF01202.17 KNZ81427.1 - 0.048 13.5 0.0 5.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase Zeta_toxin PF06414.7 KNZ81427.1 - 0.19 10.8 0.0 0.37 9.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 KNZ81427.1 - 0.33 9.7 0.0 1.1 8.0 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Gar1 PF04410.9 KNZ81428.1 - 1.7e-41 141.2 0.1 1.7e-41 141.2 0.1 1.9 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region Mis14 PF08641.7 KNZ81429.1 - 3.1e-05 24.0 0.3 6.2e-05 23.0 0.1 1.5 2 0 0 2 2 2 1 Kinetochore protein Mis14 like Thg1 PF04446.7 KNZ81429.1 - 0.073 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 tRNAHis guanylyltransferase TUG-UBL1 PF11470.3 KNZ81429.1 - 0.096 12.6 0.1 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 GLUT4 regulating protein TUG DUF572 PF04502.8 KNZ81430.1 - 1.5e-64 218.2 6.2 1.8e-64 218.0 4.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) HrpA_pilin PF09589.5 KNZ81430.1 - 0.0091 16.4 1.0 0.02 15.3 0.3 1.8 1 1 1 2 2 2 1 HrpA pilus formation protein zf-FCS PF06467.9 KNZ81430.1 - 0.011 15.2 1.2 0.29 10.8 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF866 PF05907.8 KNZ81430.1 - 0.02 14.3 0.1 0.041 13.3 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) FAM176 PF14851.1 KNZ81430.1 - 0.1 12.2 7.8 0.12 12.0 5.0 1.4 1 1 0 1 1 1 0 FAM176 family HA2 PF04408.18 KNZ81431.1 - 2.4e-18 66.0 0.0 4.6e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KNZ81431.1 - 1.1e-15 57.3 0.0 2.1e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KNZ81431.1 - 2.5e-15 56.0 0.0 5.2e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KNZ81431.1 - 1.1e-05 25.5 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KNZ81431.1 - 1.3e-05 24.8 0.0 3.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KNZ81431.1 - 0.0037 16.2 0.0 0.0072 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 KNZ81431.1 - 0.0082 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KNZ81431.1 - 0.015 15.2 0.1 0.27 11.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KNZ81431.1 - 0.029 13.7 0.0 0.27 10.6 0.0 2.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 KNZ81431.1 - 0.088 11.8 0.1 0.35 9.9 0.0 1.9 1 1 1 2 2 2 0 Zeta toxin rve PF00665.21 KNZ81433.1 - 0.017 15.2 0.0 0.068 13.2 0.0 2.0 3 0 0 3 3 3 0 Integrase core domain Asp_protease_2 PF13650.1 KNZ81433.1 - 0.06 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.18 KNZ81433.1 - 0.067 13.1 0.5 0.16 11.9 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.1 KNZ81435.1 - 0.0017 18.8 0.0 0.0047 17.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ81435.1 - 0.12 11.8 0.2 0.25 10.9 0.1 1.5 1 1 0 1 1 1 0 Aspartyl protease SPT2 PF08243.6 KNZ81437.1 - 0.95 9.7 5.9 1.5 9.1 4.1 1.3 1 0 0 1 1 1 0 SPT2 chromatin protein Myosin_head PF00063.16 KNZ81439.1 - 2.2e-241 802.7 0.0 2.2e-241 802.7 0.0 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 KNZ81439.1 - 2.3e-33 114.2 2.0 2.3e-33 114.2 1.4 2.8 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 KNZ81439.1 - 1.4e-10 39.8 33.7 0.018 14.6 1.1 7.0 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 KNZ81439.1 - 0.057 13.5 0.0 0.057 13.5 0.0 3.3 2 1 1 3 3 3 0 AAA domain zf-AN1 PF01428.11 KNZ81440.1 - 1.1e-07 31.5 3.1 1.8e-07 30.9 2.1 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger S1_2 PF13509.1 KNZ81440.1 - 0.022 14.6 0.1 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 S1 domain Snf7 PF03357.16 KNZ81441.1 - 4.4e-40 136.8 23.6 6.8e-40 136.2 15.8 1.6 2 0 0 2 2 2 1 Snf7 Glyco_hydro_17 PF00332.13 KNZ81441.1 - 0.032 13.2 0.2 0.043 12.8 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 HCMV_UL139 PF12507.3 KNZ81441.1 - 0.037 14.1 1.6 0.082 13.0 1.1 1.6 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein BPL_N PF09825.4 KNZ81441.1 - 0.28 9.8 1.9 0.41 9.3 0.4 1.7 1 1 1 2 2 2 0 Biotin-protein ligase, N terminal V_ATPase_I PF01496.14 KNZ81441.1 - 0.68 7.7 6.7 0.92 7.2 4.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ist1 PF03398.9 KNZ81441.1 - 1.1 8.6 7.4 1.8 7.9 5.1 1.3 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF1002 PF06207.6 KNZ81441.1 - 1.1 8.4 9.8 0.09 12.0 1.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1002) DUF3682 PF12446.3 KNZ81441.1 - 1.3 9.2 4.8 0.76 10.0 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3682) Pox_A_type_inc PF04508.7 KNZ81441.1 - 2.3 8.2 6.6 2.5 8.0 2.5 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Spc24 PF08286.6 KNZ81441.1 - 4.9 6.8 12.4 0.75 9.5 0.9 2.6 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 COG4 PF08318.7 KNZ81442.1 - 1.7e-57 194.7 0.0 3.7e-57 193.5 0.0 1.5 2 0 0 2 2 2 1 COG4 transport protein DUF651 PF04895.7 KNZ81442.1 - 0.076 12.6 0.0 0.29 10.7 0.0 2.0 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF651) PIF1 PF05970.9 KNZ81443.1 - 1.4e-11 43.9 0.0 1.9e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Glyco_hydro_3 PF00933.16 KNZ81445.1 - 2.6e-75 253.1 0.0 3.6e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KNZ81445.1 - 5.1e-65 219.1 0.0 2.1e-64 217.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KNZ81445.1 - 3.4e-22 78.1 0.2 7.6e-22 77.0 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KNZ81445.1 - 2.3e-07 30.5 0.0 4.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 PA14 domain PIG-S PF10510.4 KNZ81445.1 - 0.0032 16.2 0.0 0.0049 15.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DinI PF06183.8 KNZ81445.1 - 0.17 11.9 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 DinI-like family DUF2340 PF10209.4 KNZ81446.1 - 1.4e-37 128.6 0.5 2.2e-37 127.9 0.4 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) CN_hydrolase PF00795.17 KNZ81447.1 - 3.4e-30 104.7 0.0 5.9e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DnaJ PF00226.26 KNZ81447.1 - 9.9e-22 76.4 1.7 1.6e-21 75.8 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KNZ81447.1 - 6.7e-17 61.1 0.1 1.9e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 DnaJ C terminal domain Methyltransf_12 PF08242.7 KNZ81447.1 - 0.13 12.7 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DAGK_cat PF00781.19 KNZ81448.1 - 9.9e-13 47.6 0.0 1.5e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ADK PF00406.17 KNZ81449.1 - 1.2e-44 151.8 0.1 2.4e-44 150.8 0.1 1.5 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 KNZ81449.1 - 1.5e-07 32.2 0.0 2.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KNZ81449.1 - 1.3e-05 25.1 0.2 0.00025 20.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KNZ81449.1 - 1.9e-05 24.9 0.0 2.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 KNZ81449.1 - 0.044 13.2 0.3 0.13 11.7 0.1 1.9 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.12 KNZ81449.1 - 0.078 12.3 0.3 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase WD40 PF00400.27 KNZ81450.1 - 7.4e-07 28.8 0.9 4.1e-05 23.2 0.0 3.3 2 1 0 2 2 2 1 WD domain, G-beta repeat Fungal_trans PF04082.13 KNZ81451.1 - 2.7e-18 65.8 0.1 5.5e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ81451.1 - 0.067 13.1 3.5 0.13 12.2 2.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.17 KNZ81452.1 - 3.7e-17 61.6 1.0 4.8e-17 61.2 0.7 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KNZ81452.1 - 0.042 13.7 0.1 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.12 KNZ81452.1 - 0.084 12.5 0.2 0.73 9.5 0.1 2.1 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain Glyco_hydro_63 PF03200.11 KNZ81454.1 - 4.1e-227 755.8 0.0 3.4e-226 752.8 0.0 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 KNZ81454.1 - 5.2e-05 22.0 0.0 9.2e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 KNZ81454.1 - 0.00092 18.0 0.0 0.0016 17.2 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase FH2 PF02181.18 KNZ81455.1 - 9.8e-67 225.4 6.2 9.8e-67 225.4 4.3 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 KNZ81455.1 - 5.8e-35 120.5 2.2 5.8e-35 120.5 1.5 2.7 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 KNZ81455.1 - 5.9e-34 117.0 1.3 1.3e-33 116.0 0.0 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain SPOUT_MTase_2 PF14419.1 KNZ81455.1 - 0.055 12.6 0.5 0.16 11.1 0.2 1.9 2 0 0 2 2 2 0 AF2226-like SPOUT RNA Methylase fused to THUMP Prominin PF05478.6 KNZ81455.1 - 0.21 9.1 1.6 0.42 8.0 1.1 1.4 1 0 0 1 1 1 0 Prominin Zot PF05707.7 KNZ81456.1 - 0.14 11.5 0.3 0.2 11.0 0.2 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) EssA PF10661.4 KNZ81456.1 - 8.3 6.0 7.8 9.2 5.9 3.2 2.1 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA PBP PF01161.15 KNZ81457.1 - 2.8e-15 56.4 0.0 4e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein G-patch PF01585.18 KNZ81458.1 - 3.1e-13 49.2 1.4 6.4e-13 48.2 1.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KNZ81458.1 - 2.2e-05 24.1 1.3 2.2e-05 24.1 0.9 3.0 3 0 0 3 3 3 1 DExH-box splicing factor binding site RRM_1 PF00076.17 KNZ81458.1 - 0.0028 17.2 0.8 0.0055 16.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 KNZ81458.1 - 0.0037 16.5 1.6 0.0037 16.5 1.1 3.1 3 0 0 3 3 3 1 RED-like protein N-terminal region zf-C2H2_jaz PF12171.3 KNZ81458.1 - 0.011 15.8 0.4 0.022 14.9 0.3 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KNZ81458.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RRM_5 PF13893.1 KNZ81458.1 - 0.031 14.1 0.1 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.21 KNZ81458.1 - 0.05 13.9 0.9 0.11 12.9 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type COQ7 PF03232.8 KNZ81459.1 - 5.9e-68 227.6 0.2 6.8e-68 227.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 DUF3849 PF12960.2 KNZ81459.1 - 0.11 12.4 0.0 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3849) UPF0731 PF14982.1 KNZ81460.1 - 0.9 9.4 2.9 13 5.7 0.3 2.8 1 1 2 3 3 3 0 UPF0731 family PUB PF09409.5 KNZ81461.1 - 2.6e-08 33.5 0.1 4.1e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 PUB domain FAA_hydrolase_N PF09298.6 KNZ81461.1 - 0.012 15.5 2.9 0.014 15.3 0.1 2.0 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal PCI PF01399.22 KNZ81463.1 - 6.9e-10 39.1 0.0 4.9e-09 36.4 0.0 2.4 2 0 0 2 2 2 1 PCI domain Tropomyosin_1 PF12718.2 KNZ81463.1 - 0.0017 18.2 1.3 0.003 17.4 0.9 1.4 1 0 0 1 1 1 1 Tropomyosin like MarR_2 PF12802.2 KNZ81463.1 - 0.026 14.1 0.2 8.1 6.1 0.0 3.0 3 0 0 3 3 3 0 MarR family CRS1_YhbY PF01985.16 KNZ81463.1 - 0.089 12.8 0.1 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain TPR_7 PF13176.1 KNZ81463.1 - 8.4 6.4 6.8 4.6 7.2 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 KNZ81464.1 - 6.5e-63 212.3 0.0 7.8e-63 212.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81464.1 - 4.6e-32 111.0 0.0 6.1e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ81464.1 - 5.4e-08 32.1 0.0 8e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KNZ81464.1 - 0.061 12.3 0.1 0.15 11.1 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 KNZ81465.1 - 9.7e-05 22.0 0.1 0.075 12.9 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Asp PF00026.18 KNZ81466.1 - 8.7e-110 366.8 0.1 1e-109 366.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNZ81466.1 - 3.4e-09 36.8 0.0 5.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KNZ81466.1 - 3.6e-06 26.6 0.0 5.4e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KNZ81466.1 - 0.00028 21.3 0.1 0.29 11.6 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease Bromodomain PF00439.20 KNZ81467.1 - 3.6e-24 84.4 0.1 1.2e-23 82.8 0.0 1.9 2 0 0 2 2 2 1 Bromodomain FAT PF02259.18 KNZ81468.1 - 8.7e-68 228.8 4.1 1.7e-67 227.9 2.8 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KNZ81468.1 - 2.2e-13 50.2 0.1 6.4e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TPR_11 PF13414.1 KNZ81468.1 - 0.0016 18.0 1.0 0.067 12.8 0.4 3.1 3 0 0 3 3 3 1 TPR repeat FATC PF02260.15 KNZ81468.1 - 0.038 13.4 0.0 0.23 10.9 0.0 2.3 2 0 0 2 2 2 0 FATC domain TPR_8 PF13181.1 KNZ81468.1 - 0.16 11.8 0.2 9.4 6.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Thioredoxin PF00085.15 KNZ81469.1 - 1.9e-59 197.7 1.7 5.8e-30 103.0 0.1 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 KNZ81469.1 - 1.1e-41 142.7 0.2 5.9e-31 107.6 0.1 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KNZ81469.1 - 6.3e-11 42.2 0.8 0.003 17.6 0.0 3.9 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KNZ81469.1 - 4.7e-10 39.3 0.5 0.0011 18.9 0.1 3.2 3 0 0 3 3 3 2 Thioredoxin-like WH2 PF02205.15 KNZ81469.1 - 1.4e-07 30.9 1.2 9.5e-07 28.2 0.6 2.2 2 0 0 2 2 2 1 WH2 motif Thioredoxin_2 PF13098.1 KNZ81469.1 - 3.9e-07 30.2 2.4 0.0039 17.3 0.1 3.6 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 KNZ81469.1 - 1.2e-06 28.2 0.3 0.033 13.8 0.0 2.9 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 KNZ81469.1 - 5e-06 26.1 0.5 0.065 12.7 0.0 2.9 3 0 0 3 3 3 2 Redoxin Calsequestrin PF01216.12 KNZ81469.1 - 0.0019 17.0 0.6 0.0062 15.3 0.4 1.8 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_4 PF13462.1 KNZ81469.1 - 0.0079 16.2 1.0 5.7 6.9 0.0 3.4 3 1 0 3 3 3 1 Thioredoxin Spc97_Spc98 PF04130.8 KNZ81470.1 - 7.7e-112 374.3 0.1 1.2e-111 373.7 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family TCTP PF00838.12 KNZ81471.1 - 4.6e-54 182.8 1.8 5.3e-54 182.6 1.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein UTP15_C PF09384.5 KNZ81472.1 - 3.5e-48 163.0 0.1 5.5e-48 162.4 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KNZ81472.1 - 3.3e-32 109.1 5.1 9.9e-07 28.4 0.0 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KNZ81472.1 - 0.0037 16.1 0.0 0.7 8.6 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region Cytochrom_D1 PF02239.11 KNZ81472.1 - 0.015 13.6 0.0 0.17 10.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain CAF1C_H4-bd PF12265.3 KNZ81472.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex CTNNBL PF08216.6 KNZ81473.1 - 6.9e-29 99.5 0.0 2.6e-28 97.7 0.0 2.0 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 KNZ81473.1 - 0.24 11.2 1.3 1.8 8.5 0.1 3.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat CorA PF01544.13 KNZ81473.1 - 4.4 6.2 11.9 4.1 6.3 0.0 2.8 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein RRM_1 PF00076.17 KNZ81474.1 - 3.3e-16 58.6 0.0 5e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KNZ81474.1 - 1.4e-09 37.7 0.0 2.1e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KNZ81474.1 - 0.0021 17.8 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L18p PF00861.17 KNZ81475.1 - 1.8e-41 141.0 0.1 3.8e-41 140.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KNZ81475.1 - 2.9e-34 117.4 1.3 2.9e-34 117.4 0.9 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region K_oxygenase PF13434.1 KNZ81475.1 - 0.05 12.5 0.4 0.095 11.6 0.1 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Med17 PF10156.4 KNZ81476.1 - 1.4e-29 102.7 0.0 1.9e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Fungal_trans PF04082.13 KNZ81477.1 - 8.6e-18 64.1 0.1 1.5e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ81477.1 - 3.8e-05 23.4 9.9 6.5e-05 22.7 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1216 PF06746.6 KNZ81477.1 - 0.46 10.2 2.1 0.85 9.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) DUF4111 PF13427.1 KNZ81478.1 - 0.015 15.1 0.1 0.051 13.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) Snf7 PF03357.16 KNZ81479.1 - 1.5e-27 96.0 17.0 1.5e-27 96.0 11.8 1.5 1 1 0 1 1 1 1 Snf7 cwf21 PF08312.7 KNZ81479.1 - 0.03 14.1 3.5 0.03 14.1 2.4 1.9 2 0 0 2 2 2 0 cwf21 domain Iso_dh PF00180.15 KNZ81480.1 - 1.4e-100 336.6 0.0 1.7e-100 336.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RNB PF00773.14 KNZ81481.1 - 5.8e-95 318.2 0.1 1.2e-94 317.2 0.0 1.6 1 0 0 1 1 1 1 RNB domain Piwi PF02171.12 KNZ81482.1 - 3.9e-63 213.2 0.0 5.6e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KNZ81482.1 - 7.2e-16 57.2 0.0 2.8e-15 55.4 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KNZ81482.1 - 1.3e-08 34.2 0.0 2.3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 PAZ domain Mito_carr PF00153.22 KNZ81483.1 - 2.6e-66 219.3 1.6 8.5e-23 79.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KNZ81483.1 - 4.1e-05 23.6 0.1 0.00013 22.0 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KNZ81483.1 - 0.00084 18.4 0.1 0.059 12.7 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KNZ81483.1 - 0.0014 18.3 0.1 0.16 11.9 0.1 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 KNZ81483.1 - 0.013 14.7 0.7 0.14 11.5 0.1 2.4 2 0 0 2 2 2 0 EF hand SNARE_assoc PF09335.6 KNZ81484.1 - 0.00019 21.6 0.3 0.0067 16.6 0.0 2.5 2 0 0 2 2 2 1 SNARE associated Golgi protein p12I PF12233.3 KNZ81484.1 - 2.6 8.3 10.3 27 5.1 0.1 3.3 3 0 0 3 3 3 0 Human adult T cell leukemia/lymphoma virus protein Ribosomal_L36e PF01158.13 KNZ81485.1 - 4e-38 129.3 3.8 4.6e-38 129.1 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e 4HB_MCP_1 PF12729.2 KNZ81485.1 - 0.033 13.5 0.2 0.04 13.2 0.1 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction INT_SG_DDX_CT_C PF15300.1 KNZ81485.1 - 0.15 11.5 1.5 0.27 10.7 0.1 2.1 2 1 1 3 3 3 0 INTS6/SAGE1/DDX26B/CT45 C-terminus CK_II_beta PF01214.13 KNZ81486.1 - 3.3e-60 202.7 0.1 1.3e-39 135.6 0.0 2.1 1 1 1 2 2 2 2 Casein kinase II regulatory subunit CRCB PF02537.10 KNZ81487.1 - 3e-31 107.7 19.3 3.3e-18 65.6 5.7 2.4 2 1 0 2 2 2 2 CrcB-like protein adh_short PF00106.20 KNZ81488.1 - 3.6e-16 59.5 0.1 7.7e-16 58.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ81488.1 - 5.3e-07 29.4 0.0 1.2e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KNZ81488.1 - 0.00054 19.4 0.0 0.0018 17.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.11 KNZ81488.1 - 0.0085 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 KNZ81488.1 - 0.023 14.7 0.0 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding YjeF_N PF03853.10 KNZ81488.1 - 0.029 13.9 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus ADH_zinc_N PF00107.21 KNZ81488.1 - 0.029 13.9 0.0 0.31 10.6 0.0 2.5 2 1 0 2 2 2 0 Zinc-binding dehydrogenase NAD_Gly3P_dh_N PF01210.18 KNZ81488.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NmrA PF05368.8 KNZ81488.1 - 0.042 13.0 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.13 KNZ81488.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1282 PF06930.7 KNZ81489.1 - 0.025 14.2 4.4 0.033 13.8 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) IBP39 PF11422.3 KNZ81489.1 - 0.025 14.0 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Initiator binding protein 39 kDa VID27 PF08553.5 KNZ81490.1 - 4.5e-252 838.7 2.1 5.2e-252 838.5 1.5 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Nop14 PF04147.7 KNZ81490.1 - 1.2 6.9 7.7 1.8 6.3 5.3 1.2 1 0 0 1 1 1 0 Nop14-like family Asp_protease_2 PF13650.1 KNZ81495.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease NSP10 PF09401.5 KNZ81495.1 - 0.024 14.3 0.0 0.05 13.3 0.0 1.5 1 1 0 1 1 1 0 RNA synthesis protein NSP10 Asp_protease PF09668.5 KNZ81495.1 - 0.076 12.5 0.2 0.37 10.3 0.3 1.8 1 1 1 2 2 2 0 Aspartyl protease FlxA PF14282.1 KNZ81500.1 - 0.058 13.3 0.1 0.08 12.8 0.1 1.2 1 0 0 1 1 1 0 FlxA-like protein RTA1 PF04479.8 KNZ81501.1 - 8.1e-41 139.9 2.1 1.1e-40 139.4 1.4 1.2 1 0 0 1 1 1 1 RTA1 like protein BTB_2 PF02214.17 KNZ81503.1 - 0.035 14.3 0.1 0.21 11.8 0.0 2.3 1 1 0 1 1 1 0 BTB/POZ domain Histidinol_dh PF00815.15 KNZ81504.1 - 7.2e-177 588.1 2.6 9.7e-177 587.6 1.8 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KNZ81504.1 - 5e-26 90.1 0.5 1.2e-25 88.9 0.4 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KNZ81504.1 - 1.6e-09 37.9 0.1 5.9e-09 36.0 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 KNZ81504.1 - 0.076 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain adh_short PF00106.20 KNZ81505.1 - 5.8e-31 107.6 0.1 8.9e-31 107.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ81505.1 - 2.7e-15 56.8 0.0 3.7e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ81505.1 - 7.5e-15 55.0 0.3 5.6e-14 52.2 0.2 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KNZ81505.1 - 4.6e-08 33.2 0.1 7.5e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KNZ81505.1 - 6.2e-07 29.0 0.0 1.7e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KNZ81505.1 - 0.057 12.1 0.0 0.27 9.9 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 KNZ81505.1 - 0.098 12.4 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Amidohydro_2 PF04909.9 KNZ81506.1 - 3.1e-28 99.0 0.1 3.8e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Iso_dh PF00180.15 KNZ81508.1 - 1.6e-43 149.0 0.1 4.5e-26 91.6 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase Cut8_N PF14482.1 KNZ81509.1 - 4.5 7.3 6.8 3.5 7.6 1.8 2.6 1 1 1 2 2 2 0 Cut8 proteasome-binding domain DUF262 PF03235.9 KNZ81510.1 - 1.4e-09 38.2 0.2 3.7e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF262 DUF2036 PF09724.4 KNZ81511.1 - 1.2e-62 211.9 0.0 1.4e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) TFR_dimer PF04253.10 KNZ81512.1 - 6.3e-14 51.6 0.2 1e-12 47.6 0.0 2.3 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KNZ81512.1 - 4.5e-13 49.3 0.0 3.3e-12 46.5 0.0 2.3 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KNZ81512.1 - 1.8e-07 30.7 0.1 3.8e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 PA domain Choline_kinase PF01633.15 KNZ81512.1 - 0.012 15.1 1.1 0.023 14.2 0.8 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Nicastrin PF05450.10 KNZ81512.1 - 0.051 12.8 0.1 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 Nicastrin DUF904 PF06005.7 KNZ81513.1 - 1.5 9.1 19.7 6.3 7.1 1.6 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 KNZ81513.1 - 3.2 7.6 6.6 3.1 7.6 0.9 2.9 2 0 0 2 2 2 0 Basic region leucine zipper Clat_adaptor_s PF01217.15 KNZ81514.1 - 1.6e-51 173.7 0.3 1.8e-51 173.5 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Gln-synt_C PF00120.19 KNZ81515.1 - 2.5e-62 210.3 0.0 3e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KNZ81515.1 - 3.5e-17 61.7 0.0 7.3e-17 60.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF2264 PF10022.4 KNZ81516.1 - 2.7e-130 434.2 0.7 3.4e-130 433.9 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) DnaJ PF00226.26 KNZ81517.1 - 4.6e-18 64.7 0.0 8.1e-18 63.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain OAD_gamma PF04277.8 KNZ81517.1 - 0.054 13.8 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain TFIIA PF03153.8 KNZ81518.1 - 0.027 14.3 3.9 0.037 13.9 2.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 KNZ81518.1 - 0.028 12.4 1.1 0.039 11.9 0.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KNZ81518.1 - 0.1 10.5 14.0 0.16 9.9 9.7 1.2 1 0 0 1 1 1 0 Nop14-like family PolyA_pol_arg_C PF12626.2 KNZ81518.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus DUF2890 PF11081.3 KNZ81518.1 - 1.3 9.0 9.5 2.7 8.0 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) BUD22 PF09073.5 KNZ81518.1 - 1.8 7.5 13.0 3.3 6.6 9.0 1.3 1 0 0 1 1 1 0 BUD22 U79_P34 PF03064.11 KNZ81519.1 - 6.4 6.2 13.0 13 5.1 9.0 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 MAP7 PF05672.6 KNZ81519.1 - 8.3 5.7 34.6 15 4.9 24.0 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF2051 PF09738.4 KNZ81520.1 - 0.02 14.2 1.5 0.02 14.2 1.0 2.1 1 1 1 2 2 2 0 Double stranded RNA binding protein (DUF2051) EF-hand_3 PF09069.6 KNZ81520.1 - 0.046 13.7 0.1 5.8 7.0 0.0 2.6 2 0 0 2 2 2 0 EF-hand BCDHK_Adom3 PF10436.4 KNZ81520.1 - 0.047 13.2 0.2 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase ApoO PF09769.4 KNZ81520.1 - 0.05 13.3 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein O ING PF12998.2 KNZ81520.1 - 1.7 8.9 5.4 1.2 9.4 0.2 2.6 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding TBPIP PF07106.8 KNZ81521.1 - 0.0026 17.3 1.1 0.0032 17.0 0.8 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DASH_Dam1 PF08653.5 KNZ81521.1 - 0.061 13.0 0.1 0.097 12.4 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 TraC PF07820.7 KNZ81521.1 - 0.13 12.4 0.6 11 6.2 0.1 2.2 2 0 0 2 2 2 0 TraC-like protein HAD_2 PF13419.1 KNZ81522.1 - 7e-24 85.0 0.1 8.6e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KNZ81522.1 - 2e-05 24.1 0.0 4.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KNZ81522.1 - 4.6e-05 23.9 0.0 5.2e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Globin PF00042.17 KNZ81522.1 - 0.016 15.5 0.0 0.039 14.2 0.0 1.6 2 0 0 2 2 2 0 Globin Ribosomal_L6e PF01159.14 KNZ81523.1 - 1.3e-36 125.1 0.0 2e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e AftA_N PF12250.3 KNZ81523.1 - 0.028 13.1 0.0 0.032 12.9 0.0 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal ROS_MUCR PF05443.6 KNZ81523.1 - 0.041 13.6 0.0 5.3 6.8 0.0 2.3 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein 60KD_IMP PF02096.15 KNZ81524.1 - 7.3e-16 58.4 0.5 2e-15 56.9 0.3 1.6 1 1 0 1 1 1 1 60Kd inner membrane protein Histone PF00125.19 KNZ81525.1 - 5.7e-28 96.8 0.3 9.9e-28 96.0 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KNZ81525.1 - 0.00083 19.4 0.2 0.0013 18.8 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KNZ81525.1 - 0.0049 16.8 0.6 0.0092 16.0 0.1 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2360 PF10152.4 KNZ81525.1 - 0.0089 16.3 0.8 0.013 15.8 0.6 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) DUF2833 PF11090.3 KNZ81526.1 - 0.043 13.9 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) TRAM_LAG1_CLN8 PF03798.11 KNZ81527.1 - 6.2e-32 110.7 26.9 6.2e-32 110.7 18.6 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KNZ81527.1 - 8.2e-07 28.4 0.0 8.2e-07 28.4 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein RNase_T PF00929.19 KNZ81528.1 - 1.8e-19 70.6 0.0 5.2e-19 69.1 0.0 1.7 2 0 0 2 2 2 1 Exonuclease CHORD PF04968.7 KNZ81528.1 - 0.0086 16.2 4.8 0.02 15.1 3.3 1.6 1 0 0 1 1 1 1 CHORD zf-CCCH_2 PF14608.1 KNZ81528.1 - 0.051 13.5 3.0 0.16 11.9 2.0 1.9 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type UPF0183 PF03676.9 KNZ81529.1 - 4.4e-44 150.6 0.0 8.7e-44 149.6 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) DNA_pol_E_B PF04042.11 KNZ81530.1 - 3.2e-41 140.9 1.0 4.9e-41 140.2 0.7 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF4047 PF13256.1 KNZ81530.1 - 0.13 12.2 1.0 0.21 11.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Fmp27_GFWDK PF10347.4 KNZ81531.1 - 2.7e-43 147.6 0.0 5.9e-43 146.4 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 KNZ81531.1 - 1.9e-40 139.1 0.1 3.2e-40 138.3 0.1 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 KNZ81531.1 - 6.2e-40 137.0 0.0 1.1e-23 83.4 0.0 3.5 1 1 2 3 3 3 3 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KNZ81531.1 - 1e-26 93.5 0.1 5e-26 91.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 KNZ81531.1 - 1.3e-12 48.0 0.0 3.5e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2985 PF11204.3 KNZ81532.1 - 6e-28 96.4 6.3 1.6e-27 95.0 4.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) OMPdecase PF00215.19 KNZ81533.1 - 2.9e-62 210.0 0.0 3.5e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family GHL5 PF14872.1 KNZ81533.1 - 0.018 12.8 0.2 0.077 10.7 0.0 1.8 2 0 0 2 2 2 0 Hypothetical glycoside hydrolase 5 TruD PF01142.13 KNZ81534.1 - 4.2e-66 223.1 0.1 6.4e-65 219.2 0.0 2.6 3 1 0 3 3 3 1 tRNA pseudouridine synthase D (TruD) API5 PF05918.6 KNZ81534.1 - 8.6 4.7 19.3 0.04 12.4 2.3 2.2 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) MFS_1 PF07690.11 KNZ81535.1 - 7.3e-28 97.2 20.6 3.5e-27 95.0 9.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 KNZ81535.1 - 0.00029 19.6 0.2 0.00054 18.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF791) TRI12 PF06609.8 KNZ81535.1 - 0.0064 14.7 1.8 0.0094 14.1 1.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gly_transf_sug PF04488.10 KNZ81536.1 - 4.2e-20 72.0 0.0 8e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KNZ81536.1 - 0.013 13.9 1.8 0.095 11.1 0.1 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 KNZ81536.1 - 0.046 12.8 0.1 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein PIN_4 PF13638.1 KNZ81537.1 - 6.8e-16 58.5 0.0 1.6e-15 57.4 0.0 1.6 1 1 0 1 1 1 1 PIN domain HTH_32 PF13565.1 KNZ81537.1 - 0.017 15.9 0.7 3.6 8.4 0.2 2.8 2 1 0 2 2 2 0 Homeodomain-like domain CTD_bind PF04818.8 KNZ81538.1 - 0.0013 18.9 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 KNZ81538.1 - 0.052 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 zf-C2H2_4 PF13894.1 KNZ81538.1 - 0.2 12.0 1.9 29 5.2 0.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KNZ81538.1 - 0.25 11.0 1.9 0.51 10.0 0.2 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Ribosomal_L6 PF00347.18 KNZ81539.1 - 6.9e-29 100.1 5.7 1e-15 57.9 1.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 CBM_4_9 PF02018.12 KNZ81539.1 - 0.03 14.3 0.1 0.15 12.0 0.0 1.9 1 1 1 2 2 2 0 Carbohydrate binding domain MT PF12777.2 KNZ81539.1 - 0.13 10.9 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor ICMT PF04140.9 KNZ81540.1 - 1.9e-24 85.6 0.7 3.2e-24 84.9 0.5 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KNZ81540.1 - 5.2e-12 45.7 2.1 5.2e-12 45.7 1.4 1.6 1 1 0 1 1 1 1 Phospholipid methyltransferase NnrU PF07298.6 KNZ81540.1 - 0.0044 16.4 5.1 0.0077 15.6 3.6 1.4 1 1 0 1 1 1 1 NnrU protein GTP_EFTU PF00009.22 KNZ81541.1 - 2.3e-50 170.6 0.0 3.5e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KNZ81541.1 - 4.7e-14 51.9 0.0 8.8e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KNZ81541.1 - 8.6e-14 51.1 0.0 3.9e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KNZ81541.1 - 8.2e-06 25.8 0.0 2.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KNZ81541.1 - 0.00092 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KNZ81541.1 - 0.028 13.6 0.1 0.076 12.2 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MobB PF03205.9 KNZ81541.1 - 0.16 11.6 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NAD_binding_1 PF00175.16 KNZ81543.1 - 2.6e-09 37.5 0.0 7.8e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KNZ81543.1 - 2.9e-09 36.9 0.0 4.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KNZ81543.1 - 6.3e-05 22.9 0.0 0.0089 15.9 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain ADH_zinc_N PF00107.21 KNZ81544.1 - 4.9e-23 81.1 0.0 8.4e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ81544.1 - 1.7e-21 75.9 0.7 3.4e-21 75.0 0.0 1.8 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KNZ81544.1 - 0.00014 22.7 0.1 0.00037 21.3 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KNZ81544.1 - 0.00026 21.5 0.0 0.00053 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 KNZ81544.1 - 0.0028 17.2 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 KNZ81544.1 - 0.014 14.7 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PrmA PF06325.8 KNZ81544.1 - 0.025 13.7 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 KNZ81544.1 - 0.052 14.0 0.0 0.095 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ81544.1 - 0.061 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KNZ81544.1 - 0.09 12.1 0.1 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 KNZ81544.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ81544.1 - 0.12 12.4 0.3 0.34 10.9 0.2 1.8 1 1 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 KNZ81545.1 - 6.8e-41 140.1 0.0 2.5e-19 69.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81545.1 - 4.7e-25 88.1 0.0 1.6e-22 79.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pentapeptide_2 PF01469.13 KNZ81545.1 - 0.14 11.8 0.9 0.24 11.0 0.7 1.3 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Meth_synt_2 PF01717.13 KNZ81546.1 - 6.4e-140 465.7 0.0 5.6e-136 452.7 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KNZ81546.1 - 8.2e-121 403.0 0.0 3.1e-109 365.0 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Rsd_AlgQ PF04353.8 KNZ81546.1 - 0.031 13.9 0.0 0.9 9.2 0.0 2.3 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ FAD_binding_7 PF03441.9 KNZ81547.1 - 1e-86 290.6 0.1 2.3e-86 289.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KNZ81547.1 - 2.2e-34 118.5 0.0 3.8e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase YycC PF14174.1 KNZ81547.1 - 0.026 14.1 0.1 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 YycC-like protein eRF1_1 PF03463.10 KNZ81548.1 - 1.6e-33 115.0 0.0 2.7e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 KNZ81548.1 - 2.8e-23 82.3 0.0 5.2e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 KNZ81548.1 - 2.7e-20 73.0 0.0 4.4e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Phosducin PF02114.11 KNZ81549.1 - 0.00091 18.0 0.6 0.0014 17.4 0.4 1.4 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 KNZ81549.1 - 0.0063 16.1 0.1 0.0097 15.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF1793 PF08760.6 KNZ81550.1 - 8.6e-60 201.4 0.3 1.7e-59 200.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF659 PF04937.10 KNZ81550.1 - 0.19 11.2 0.1 0.33 10.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) DUF1793 PF08760.6 KNZ81551.1 - 1.7e-62 210.3 1.3 1.7e-62 210.3 0.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Glyco_hydro_18 PF00704.23 KNZ81552.1 - 2.1e-53 181.9 0.1 2.5e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1793 PF08760.6 KNZ81553.1 - 8e-59 198.3 1.2 8e-59 198.3 0.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Lebercilin PF15619.1 KNZ81554.1 - 0.017 14.5 5.7 0.023 14.1 0.6 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CALCOCO1 PF07888.6 KNZ81554.1 - 0.026 12.8 0.7 0.041 12.1 0.5 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like NYD-SP28_assoc PF14775.1 KNZ81554.1 - 0.15 11.7 0.8 0.47 10.1 0.6 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain CoA_binding_3 PF13727.1 KNZ81554.1 - 0.25 11.1 2.4 0.54 10.0 1.7 1.5 1 0 0 1 1 1 0 CoA-binding domain Striatin PF08232.7 KNZ81554.1 - 0.42 10.9 2.6 0.78 10.0 1.3 1.9 1 1 0 1 1 1 0 Striatin family TMF_DNA_bd PF12329.3 KNZ81554.1 - 0.94 9.3 5.4 14 5.5 0.3 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Med4 PF10018.4 KNZ81554.1 - 1.6 8.0 6.9 0.19 11.1 0.7 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 ADIP PF11559.3 KNZ81554.1 - 5.4 6.8 7.1 0.36 10.7 1.4 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HR1 PF02185.11 KNZ81554.1 - 7 6.4 7.0 0.67 9.7 0.6 2.1 2 0 0 2 2 2 0 Hr1 repeat Ank_4 PF13637.1 KNZ81556.1 - 2.9e-29 100.9 2.4 4.3e-14 52.5 0.1 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 KNZ81556.1 - 2.4e-25 88.7 0.0 4e-17 62.3 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ81556.1 - 4e-22 76.8 0.3 6.7e-09 35.1 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KNZ81556.1 - 2.8e-20 71.8 0.7 5.4e-10 39.1 0.1 4.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ81556.1 - 4.9e-16 57.2 0.6 3.6e-05 23.5 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat MFS_2 PF13347.1 KNZ81557.1 - 1.1e-09 37.2 1.1 1.1e-09 37.2 0.8 2.6 1 1 0 2 2 2 1 MFS/sugar transport protein DUF2198 PF09964.4 KNZ81557.1 - 0.3 10.8 0.0 0.3 10.8 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) DUF2207 PF09972.4 KNZ81557.1 - 0.98 7.9 4.6 2.9 6.3 0.0 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) ATP_bind_4 PF01902.12 KNZ81558.1 - 3.7e-40 137.6 0.0 1.2e-31 109.7 0.0 2.2 1 1 1 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 KNZ81558.1 - 3.8e-22 78.3 0.0 1.4e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP B3_4 PF03483.12 KNZ81559.1 - 3.9e-26 91.5 0.1 8.3e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KNZ81559.1 - 1.1e-18 66.8 0.0 1.1e-13 50.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 KNZ81559.1 - 0.016 14.4 0.0 0.093 11.9 0.0 2.0 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) TraW_N PF12477.3 KNZ81560.1 - 0.84 9.6 3.3 8.4 6.4 0.2 2.4 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal DUF2370 PF10176.4 KNZ81562.1 - 1e-68 231.2 0.1 1.9e-68 230.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Acetyltransf_1 PF00583.19 KNZ81563.1 - 8.6e-11 41.7 0.3 2.9e-10 40.0 0.2 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KNZ81563.1 - 4e-09 36.5 0.0 5.6e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KNZ81563.1 - 5.4e-06 26.6 0.1 1.8e-05 24.8 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KNZ81563.1 - 8.4e-06 25.7 0.0 1.2e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KNZ81563.1 - 1.1e-05 25.0 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KNZ81563.1 - 0.0014 18.4 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 KNZ81563.1 - 0.0017 18.3 0.1 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KNZ81563.1 - 0.0028 17.7 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1212 PF06738.7 KNZ81564.1 - 3.2e-29 101.7 3.6 3.2e-29 101.7 2.5 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KNZ81564.1 - 1.1e-13 51.2 10.1 1.1e-13 51.2 7.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF3815) tRNA-synt_2d PF01409.15 KNZ81565.1 - 1e-85 286.9 0.0 2.4e-84 282.4 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KNZ81565.1 - 8.5e-05 22.2 0.1 0.0002 20.9 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 KNZ81565.1 - 0.00011 21.0 1.3 0.0023 16.7 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) Asp_protease_2 PF13650.1 KNZ81566.1 - 1.1e-06 29.0 0.0 2.2e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ81566.1 - 0.0013 18.2 0.1 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease EB1_binding PF05937.6 KNZ81569.1 - 0.014 15.8 0.2 0.014 15.7 0.1 1.1 1 0 0 1 1 1 0 EB-1 Binding Domain Ecl1 PF12855.2 KNZ81571.1 - 0.01 15.1 0.1 0.02 14.2 0.1 1.5 1 0 0 1 1 1 0 Life-span regulatory factor S4_2 PF13275.1 KNZ81571.1 - 0.19 11.3 1.2 7.7 6.2 1.2 2.1 2 0 0 2 2 2 0 S4 domain OGFr_N PF04664.8 KNZ81573.1 - 1.5e-55 187.8 0.0 2e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Sec1 PF00995.18 KNZ81574.1 - 2.5e-128 429.2 0.0 5.9e-128 427.9 0.0 1.5 2 0 0 2 2 2 1 Sec1 family COPIIcoated_ERV PF07970.7 KNZ81574.1 - 6.1e-67 225.4 0.1 1e-66 224.7 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KNZ81574.1 - 1.7e-26 91.9 0.3 1.7e-26 91.9 0.2 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Mnd1 PF03962.10 KNZ81575.1 - 1.3 8.6 14.1 0.065 12.8 5.5 1.9 2 0 0 2 2 2 0 Mnd1 family RasGEF PF00617.14 KNZ81576.1 - 1.2e-50 171.8 0.0 2.6e-50 170.7 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KNZ81576.1 - 5.6e-20 71.3 0.0 1.7e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 KNZ81576.1 - 1.4e-14 53.4 0.0 2.6e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KNZ81576.1 - 3.9e-12 45.4 0.0 7.9e-12 44.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KNZ81576.1 - 6.2e-12 44.7 0.0 1.1e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain F-box PF00646.28 KNZ81577.1 - 6.7e-06 25.6 0.1 1.8e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KNZ81577.1 - 4.6e-05 23.0 0.2 0.00011 21.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like Tox-SGS PF15651.1 KNZ81577.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Salivary glad secreted protein domain toxin Miro PF08477.8 KNZ81578.1 - 5.4e-35 120.4 0.1 4.5e-20 72.3 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 KNZ81578.1 - 4.5e-33 112.8 0.0 9.8e-33 111.7 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 KNZ81578.1 - 2.9e-30 103.3 0.4 6e-30 102.3 0.3 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 KNZ81578.1 - 1.1e-28 99.6 0.0 2.7e-22 78.8 0.0 2.4 2 0 0 2 2 2 2 Ras family VWA_2 PF13519.1 KNZ81578.1 - 6.1e-12 45.9 0.0 3e-11 43.7 0.0 2.1 2 0 0 2 2 1 1 von Willebrand factor type A domain Arf PF00025.16 KNZ81578.1 - 3.1e-09 36.3 0.0 0.00021 20.5 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family EF-hand_6 PF13405.1 KNZ81578.1 - 4.9e-09 35.3 0.3 0.0018 18.0 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KNZ81578.1 - 9.6e-09 33.9 1.4 0.00091 18.3 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KNZ81578.1 - 3.2e-08 33.5 0.4 0.0072 16.4 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair MMR_HSR1 PF01926.18 KNZ81578.1 - 1.3e-07 31.5 0.1 0.0002 21.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_5 PF13202.1 KNZ81578.1 - 1.2e-06 27.6 4.1 0.0012 18.0 0.1 2.9 2 0 0 2 2 2 2 EF hand VWA PF00092.23 KNZ81578.1 - 5.3e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain EF-hand_10 PF14788.1 KNZ81578.1 - 0.00048 19.7 1.9 0.013 15.1 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KNZ81578.1 - 0.00052 19.5 0.7 0.35 10.5 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair AAA_22 PF13401.1 KNZ81578.1 - 0.0008 19.5 0.0 0.14 12.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KNZ81578.1 - 0.0012 19.1 0.1 0.38 11.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KNZ81578.1 - 0.0018 18.2 0.2 0.28 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 KNZ81578.1 - 0.004 17.4 0.0 0.64 10.3 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA PF00004.24 KNZ81578.1 - 0.0043 17.2 0.0 0.44 10.7 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KNZ81578.1 - 0.011 15.2 0.4 0.092 12.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.1 KNZ81578.1 - 0.016 14.7 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain SPARC_Ca_bdg PF10591.4 KNZ81578.1 - 0.018 15.0 0.0 1.4 8.9 0.0 2.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region AIG1 PF04548.11 KNZ81578.1 - 0.031 13.3 0.0 0.065 12.3 0.0 1.5 1 0 0 1 1 1 0 AIG1 family MobB PF03205.9 KNZ81578.1 - 0.037 13.7 0.2 0.19 11.3 0.1 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KNZ81578.1 - 0.039 13.9 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KNZ81578.1 - 0.041 13.5 0.2 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 KNZ81578.1 - 0.045 12.9 0.0 0.19 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Septin PF00735.13 KNZ81578.1 - 0.045 12.7 0.0 0.1 11.5 0.0 1.5 2 0 0 2 2 1 0 Septin AAA_17 PF13207.1 KNZ81578.1 - 0.088 13.6 0.9 26 5.6 0.0 3.7 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.4 KNZ81578.1 - 0.12 11.8 0.0 26 4.3 0.0 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 KNZ81578.1 - 0.13 12.0 1.0 8.1 6.2 0.0 3.2 3 0 0 3 3 3 0 Dynamin family AAA_5 PF07728.9 KNZ81578.1 - 0.15 11.7 0.0 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SBDS PF01172.13 KNZ81578.1 - 0.3 10.8 1.0 13 5.6 0.0 3.0 3 0 0 3 3 3 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein ATP_bind_1 PF03029.12 KNZ81578.1 - 1.2 8.6 4.1 92 2.4 0.0 3.9 3 1 0 4 4 4 0 Conserved hypothetical ATP binding protein Hex_IIIa PF02455.11 KNZ81579.1 - 1.4 7.4 8.0 2.1 6.9 5.6 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) HSP20 PF00011.16 KNZ81581.1 - 0.00015 21.5 0.0 0.0046 16.7 0.0 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Chromo PF00385.19 KNZ81584.1 - 1.1e-15 56.9 0.2 1.3e-15 56.7 0.2 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KNZ81584.1 - 0.094 12.6 0.2 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Tudor-knot PF11717.3 KNZ81584.1 - 0.14 11.9 0.8 0.17 11.6 0.6 1.2 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF924 PF06041.6 KNZ81588.1 - 0.01 15.5 0.7 0.013 15.2 0.1 1.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF924) KH_1 PF00013.24 KNZ81591.1 - 1.3e-08 34.3 0.2 0.00027 20.5 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 KNZ81591.1 - 5e-05 22.8 0.5 0.0036 16.9 0.0 2.6 2 0 0 2 2 2 1 KH domain Trp_repressor PF01371.14 KNZ81591.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein CBM_19 PF03427.8 KNZ81592.1 - 0.00017 21.2 0.8 0.00017 21.2 0.5 3.4 3 1 1 4 4 4 1 Carbohydrate binding domain (family 19) FTR1 PF03239.9 KNZ81593.1 - 4.6e-62 209.7 15.9 5.8e-62 209.3 11.0 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4131 PF13567.1 KNZ81593.1 - 1.1 8.6 7.2 2.1 7.7 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Cu-oxidase PF00394.17 KNZ81594.1 - 9.5e-37 126.3 0.0 6.6e-35 120.3 0.0 2.9 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KNZ81594.1 - 2e-35 121.2 4.4 1.8e-33 115.0 0.1 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KNZ81594.1 - 1.8e-33 114.7 2.1 3.4e-32 110.6 0.3 3.4 3 1 0 4 4 4 1 Multicopper oxidase HIG_1_N PF04588.8 KNZ81595.1 - 6.1e-21 73.9 0.8 8.6e-21 73.4 0.6 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DJ-1_PfpI PF01965.19 KNZ81595.1 - 0.057 12.8 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family NnrU PF07298.6 KNZ81595.1 - 0.071 12.4 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 NnrU protein DUF2413 PF10310.4 KNZ81595.1 - 0.13 11.0 6.3 0.16 10.7 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF4066 PF13278.1 KNZ81595.1 - 0.14 11.4 0.1 0.2 10.9 0.1 1.5 1 1 0 1 1 1 0 Putative amidotransferase DUF4336 PF14234.1 KNZ81596.1 - 5.6e-09 35.5 0.0 0.00022 20.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) Hira PF07569.6 KNZ81597.1 - 8.9e-47 159.1 0.0 2.3e-46 157.7 0.0 1.8 1 1 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 KNZ81597.1 - 2.6e-35 119.0 19.2 5.1e-09 35.6 0.1 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat MFS_1 PF07690.11 KNZ81598.1 - 1.2e-12 47.2 19.2 1.7e-12 46.7 13.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-PARP PF00645.13 KNZ81599.1 - 1.9e-22 79.2 0.0 4.8e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region ThylakoidFormat PF11264.3 KNZ81600.1 - 0.03 13.9 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 Thylakoid formation protein p450 PF00067.17 KNZ81601.1 - 1.7e-51 175.1 0.0 2.6e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ni_hydr_CYTB PF01292.15 KNZ81601.1 - 0.0097 15.3 0.1 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 Cytochrom_B_N PF00033.14 KNZ81601.1 - 0.02 14.2 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Ribosomal_S26e PF01283.14 KNZ81602.1 - 2.3e-50 169.5 8.2 2.7e-50 169.3 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 KNZ81602.1 - 0.099 11.9 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Pkinase PF00069.20 KNZ81604.1 - 2.5e-62 210.3 0.0 3.3e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81604.1 - 7.5e-32 110.4 0.0 9.7e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ81604.1 - 0.052 12.4 0.0 0.98 8.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like SRP1_TIP1 PF00660.12 KNZ81606.1 - 0.0078 16.0 0.5 3.7 7.4 0.2 2.6 2 0 0 2 2 2 2 Seripauperin and TIP1 family NUDIX PF00293.23 KNZ81607.1 - 5.2e-09 35.8 0.3 8.9e-09 35.1 0.2 1.3 1 0 0 1 1 1 1 NUDIX domain CKAP2_C PF15297.1 KNZ81607.1 - 0.12 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DAO PF01266.19 KNZ81608.1 - 2.4e-21 76.0 0.2 3.5e-14 52.4 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KNZ81608.1 - 0.00021 21.2 0.0 0.0059 16.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KNZ81608.1 - 0.0015 17.4 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KNZ81608.1 - 0.0055 17.0 1.9 0.013 15.9 1.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ81608.1 - 0.014 15.4 0.3 0.035 14.1 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KNZ81608.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KNZ81608.1 - 0.021 13.9 0.3 0.035 13.1 0.2 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.1 KNZ81608.1 - 0.053 13.7 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 KNZ81608.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KNZ81608.1 - 0.14 11.4 0.9 0.25 10.6 0.6 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 KNZ81608.1 - 0.18 10.2 0.4 0.26 9.6 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 KNZ81609.1 - 1.8e-21 76.5 0.3 1.1e-20 73.9 0.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ81609.1 - 0.00037 19.4 0.0 0.00062 18.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 KNZ81609.1 - 0.011 15.9 0.3 0.019 15.2 0.2 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.12 KNZ81609.1 - 0.03 13.4 0.1 0.046 12.8 0.1 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 KNZ81609.1 - 0.083 12.9 0.2 0.3 11.1 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KNZ81609.1 - 0.13 12.1 0.0 0.31 10.8 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glycos_transf_1 PF00534.15 KNZ81610.1 - 6.6e-25 87.5 0.0 1.1e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KNZ81610.1 - 4.3e-13 49.5 0.0 7.9e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 PIGA PF08288.7 KNZ81610.1 - 2.1e-05 24.7 0.6 0.00014 22.1 0.1 2.7 3 0 0 3 3 3 1 PIGA (GPI anchor biosynthesis) Glyco_trans_1_2 PF13524.1 KNZ81610.1 - 0.0035 17.5 0.0 0.0084 16.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Abhydrolase_6 PF12697.2 KNZ81611.1 - 1e-27 97.4 0.2 1.5e-27 96.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ81611.1 - 2.8e-14 53.2 0.0 9.9e-14 51.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KNZ81611.1 - 1.1e-10 41.4 0.0 5.6e-09 35.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KNZ81611.1 - 0.029 13.8 0.0 0.73 9.2 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DLH PF01738.13 KNZ81611.1 - 0.091 12.0 0.0 1.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.6 KNZ81611.1 - 0.18 11.4 0.0 0.42 10.2 0.0 1.5 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FA_desaturase PF00487.19 KNZ81612.1 - 1.5e-11 44.2 1.4 1.7e-11 44.0 1.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase HLH PF00010.21 KNZ81613.1 - 3.3e-05 23.4 0.0 0.00013 21.6 0.0 2.1 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain AT_hook PF02178.14 KNZ81613.1 - 0.38 10.5 7.2 1 9.2 5.0 1.8 1 0 0 1 1 1 0 AT hook motif WW PF00397.21 KNZ81615.1 - 3.6e-09 36.3 2.3 7e-09 35.3 1.6 1.5 1 0 0 1 1 1 1 WW domain PP1_bind PF15276.1 KNZ81615.1 - 1.5 8.8 8.0 0.35 10.9 2.6 2.1 2 0 0 2 2 2 0 Protein phosphatase 1 binding UNC-50 PF05216.8 KNZ81616.1 - 1.1e-84 283.2 12.4 1.2e-84 283.1 8.6 1.0 1 0 0 1 1 1 1 UNC-50 family ADSL_C PF10397.4 KNZ81617.1 - 1.9e-17 63.0 0.0 3.5e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Lyase_1 PF00206.15 KNZ81617.1 - 5.4e-10 38.9 0.0 8.5e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Lyase CorA PF01544.13 KNZ81618.1 - 1e-09 37.8 4.5 1.9e-09 37.0 3.1 1.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.11 KNZ81618.1 - 0.00064 18.5 0.1 0.0009 18.0 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3829 PF12889.2 KNZ81618.1 - 0.04 13.1 1.3 0.058 12.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) GRA6 PF05084.8 KNZ81620.1 - 0.0095 15.4 1.1 0.0095 15.4 0.8 1.9 1 1 1 2 2 2 1 Granule antigen protein (GRA6) SKG6 PF08693.5 KNZ81620.1 - 0.029 13.7 3.8 0.078 12.3 2.6 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.1 KNZ81620.1 - 0.12 12.0 1.6 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.1 KNZ81620.1 - 0.35 11.3 1.2 1.5 9.2 0.0 2.6 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain BTB PF00651.26 KNZ81621.1 - 4.9e-11 42.6 0.0 7.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Oxysterol_BP PF01237.13 KNZ81623.1 - 9.3e-47 159.2 0.0 1.1e-35 122.7 0.0 2.5 2 1 0 2 2 2 2 Oxysterol-binding protein Glyco_hydro_16 PF00722.16 KNZ81624.1 - 9.8e-07 28.2 0.1 2.5e-06 26.9 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 tRNA-synt_1 PF00133.17 KNZ81625.1 - 2.7e-150 501.2 0.0 3.4e-150 500.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KNZ81625.1 - 2.3e-22 79.1 0.1 2.5e-15 56.0 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KNZ81625.1 - 6.3e-22 77.9 0.1 1.1e-21 77.1 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 KNZ81625.1 - 1.1e-05 24.9 4.8 2.4e-05 23.8 3.4 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 KNZ81625.1 - 0.0013 17.9 0.0 0.91 8.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-RING_3 PF14369.1 KNZ81625.1 - 0.1 12.5 6.9 0.24 11.4 4.8 1.6 1 0 0 1 1 1 0 zinc-finger Fanconi_A PF03511.9 KNZ81626.1 - 0.43 10.4 3.2 15 5.4 0.0 2.8 3 0 0 3 3 3 0 Fanconi anaemia group A protein ProRS-C_1 PF09180.6 KNZ81627.1 - 2.6e-24 84.9 0.2 5.4e-24 83.8 0.1 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 KNZ81627.1 - 3.4e-21 75.5 0.0 5.7e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KNZ81627.1 - 9.8e-17 60.6 0.0 2.4e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 KNZ81627.1 - 9.8e-13 48.0 0.0 1.9e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Cyclin_N PF00134.18 KNZ81628.1 - 6.9e-46 154.9 1.9 3.9e-45 152.4 0.6 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KNZ81628.1 - 3.3e-24 85.0 0.1 7e-24 84.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Band_7 PF01145.20 KNZ81629.1 - 8.2e-26 90.9 0.0 8.2e-26 90.9 0.0 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KNZ81629.1 - 0.00015 21.3 1.0 0.0003 20.3 0.0 1.9 2 1 1 3 3 3 1 SPFH domain-Band 7 family zf-C3HC4_3 PF13920.1 KNZ81630.1 - 1.9e-08 33.8 17.7 1.5e-07 30.9 6.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KNZ81630.1 - 2.1e-07 30.6 22.7 3.8e-07 29.8 8.4 3.0 2 1 1 3 3 3 2 Ring finger domain zf-C2H2_jaz PF12171.3 KNZ81630.1 - 6e-07 29.4 12.8 0.00052 20.0 0.0 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C3HC4_2 PF13923.1 KNZ81630.1 - 7.4e-07 29.0 21.4 1.9e-06 27.7 10.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.2 KNZ81630.1 - 4.3e-06 26.7 8.8 0.018 15.2 0.0 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C3HC4 PF00097.20 KNZ81630.1 - 8.6e-06 25.3 14.3 8.6e-06 25.3 9.9 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ81630.1 - 4.9e-05 22.9 12.6 4.9e-05 22.9 8.8 3.5 2 2 1 3 3 3 1 zinc-RING finger domain zf-C2H2_4 PF13894.1 KNZ81630.1 - 0.00062 19.9 19.2 0.096 13.0 0.0 4.7 4 1 0 4 4 4 2 C2H2-type zinc finger zf-DBF PF07535.7 KNZ81630.1 - 0.00091 18.8 9.9 0.033 13.8 0.6 3.0 2 1 1 3 3 3 2 DBF zinc finger zf-C2H2_6 PF13912.1 KNZ81630.1 - 0.011 15.6 12.8 0.24 11.3 0.1 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-RING_6 PF14835.1 KNZ81630.1 - 0.41 10.4 12.0 0.41 10.4 6.5 2.3 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-C2H2 PF00096.21 KNZ81630.1 - 0.57 10.6 0.1 0.57 10.6 0.1 4.8 4 1 1 5 5 5 0 Zinc finger, C2H2 type zf-rbx1 PF12678.2 KNZ81630.1 - 3.3 7.8 20.0 0.43 10.7 7.4 2.8 1 1 1 3 3 3 0 RING-H2 zinc finger zf-H2C2_2 PF13465.1 KNZ81630.1 - 6.5 7.2 22.7 3.4 8.1 0.5 5.1 4 1 1 5 5 5 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KNZ81631.1 - 9.4e-09 35.1 1.8 0.00043 20.3 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KNZ81631.1 - 1.2e-06 28.4 0.1 0.015 15.4 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KNZ81631.1 - 1.9e-05 24.6 3.8 0.079 13.3 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KNZ81631.1 - 0.00037 20.2 3.0 0.2 11.6 0.1 2.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-DBF PF07535.7 KNZ81631.1 - 0.00064 19.3 9.9 0.026 14.2 0.6 2.9 2 1 1 3 3 3 2 DBF zinc finger zf-C2H2 PF00096.21 KNZ81631.1 - 0.0051 17.0 7.4 0.47 10.9 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KNZ81631.1 - 0.31 11.1 5.9 1.7 8.8 1.2 2.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) CBS PF00571.23 KNZ81632.1 - 3.3e-05 23.6 0.0 0.0095 15.7 0.0 2.2 2 0 0 2 2 2 2 CBS domain DNA_mis_repair PF01119.14 KNZ81633.1 - 4.7e-22 77.6 0.1 3.7e-21 74.7 0.0 2.2 2 1 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KNZ81633.1 - 2.9e-14 52.8 0.0 6.9e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KNZ81633.1 - 1.4e-11 44.0 0.0 3.1e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MOR2-PAG1_N PF14222.1 KNZ81634.1 - 6.3e-129 431.1 0.0 2.1e-128 429.4 0.0 1.9 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KNZ81634.1 - 4.7e-80 269.1 1.8 1.1e-79 267.9 1.3 1.7 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KNZ81634.1 - 2.8e-15 55.0 0.1 4.1e-10 37.9 0.0 3.0 3 0 0 3 3 3 3 Cell morphogenesis central region PC_rep PF01851.17 KNZ81635.1 - 1.7e-21 75.1 18.0 0.00035 20.6 0.1 10.0 10 0 0 10 10 10 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KNZ81635.1 - 0.00018 21.7 0.1 0.75 10.1 0.0 4.0 3 1 0 3 3 3 1 HEAT repeats HA2 PF04408.18 KNZ81635.1 - 0.038 14.0 0.3 0.16 12.0 0.2 2.0 1 0 0 1 1 1 0 Helicase associated domain (HA2) HEAT_EZ PF13513.1 KNZ81635.1 - 0.054 14.0 0.2 0.52 10.8 0.0 2.9 2 0 0 2 2 2 0 HEAT-like repeat PQ-loop PF04193.9 KNZ81636.1 - 4.8e-19 67.6 16.3 1.1e-10 40.9 0.4 3.5 3 0 0 3 3 3 2 PQ loop repeat PP2C PF00481.16 KNZ81637.1 - 3.9e-17 62.4 0.0 3e-16 59.5 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KNZ81637.1 - 0.00036 20.2 0.1 0.013 15.1 0.0 2.7 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Cyclin_N PF00134.18 KNZ81639.1 - 5.1e-40 135.9 0.6 3e-39 133.4 0.3 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KNZ81639.1 - 2.2e-21 75.9 0.0 3.6e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain FA_desaturase PF00487.19 KNZ81640.1 - 1.6e-15 57.2 17.9 2.8e-15 56.4 12.4 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KNZ81640.1 - 2e-13 49.9 0.0 5.9e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Ion_trans_2 PF07885.11 KNZ81641.1 - 4.7e-34 115.9 32.4 1.9e-19 69.1 8.1 3.2 3 0 0 3 3 3 2 Ion channel Lig_chan PF00060.21 KNZ81641.1 - 8.4e-05 22.3 4.7 0.0016 18.2 0.8 2.7 2 2 0 2 2 2 2 Ligand-gated ion channel DUF106 PF01956.11 KNZ81641.1 - 0.036 13.6 0.2 0.22 11.0 0.0 2.4 2 0 0 2 2 2 0 Integral membrane protein DUF106 rve PF00665.21 KNZ81642.1 - 1.1e-06 28.8 0.0 1.1e-06 28.7 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain LEP503 PF15221.1 KNZ81642.1 - 0.0054 16.4 0.0 0.0076 15.9 0.0 1.3 1 0 0 1 1 1 1 Lens epithelial cell protein LEP503 PIF1 PF05970.9 KNZ81643.1 - 2.1e-39 135.5 0.0 2.4e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 KNZ81643.1 - 0.04 14.0 0.0 0.094 12.8 0.0 1.7 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PIF1 PF05970.9 KNZ81644.1 - 6.8e-36 123.9 0.0 9.7e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 KNZ81644.1 - 0.019 14.7 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KNZ81644.1 - 0.027 13.9 0.1 0.043 13.3 0.1 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KNZ81644.1 - 0.027 14.0 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2791 PF10923.3 KNZ81644.1 - 0.047 12.2 0.0 0.06 11.9 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Helitron_like_N PF14214.1 KNZ81645.1 - 3.8e-21 75.6 0.0 4.8e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Xan_ur_permease PF00860.15 KNZ81647.1 - 8.7e-53 179.1 33.0 7.3e-51 172.8 22.9 2.1 1 1 0 1 1 1 1 Permease family Hist_deacetyl PF00850.14 KNZ81648.1 - 3.9e-79 266.1 0.0 5.9e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Amidase PF01425.16 KNZ81649.1 - 6.6e-84 282.2 0.0 8.3e-84 281.9 0.0 1.1 1 0 0 1 1 1 1 Amidase IBN_N PF03810.14 KNZ81652.1 - 1.4e-09 37.7 0.0 1e-07 31.7 0.0 3.4 2 1 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KNZ81652.1 - 1.8e-05 24.7 0.0 0.00016 21.6 0.0 2.8 2 1 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.1 KNZ81652.1 - 0.0013 18.9 0.4 0.22 11.8 0.0 4.3 4 2 0 4 4 4 1 HEAT repeats RIX1 PF08167.7 KNZ81652.1 - 0.0021 17.7 3.7 0.027 14.1 0.3 3.8 2 2 1 4 4 4 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 KNZ81652.1 - 0.0074 14.6 0.2 0.093 11.0 0.0 2.4 2 0 0 2 2 2 1 Adaptin N terminal region CAS_CSE1 PF03378.10 KNZ81652.1 - 0.011 14.0 0.0 0.15 10.3 0.0 2.5 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus HEAT PF02985.17 KNZ81652.1 - 0.016 15.2 5.0 0.25 11.5 0.0 5.1 6 0 0 6 6 6 0 HEAT repeat Cnd1 PF12717.2 KNZ81652.1 - 0.019 14.8 0.0 0.16 11.8 0.0 2.7 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 KNZ81652.1 - 0.028 14.3 0.0 3.8 7.3 0.0 2.9 2 0 0 2 2 2 0 Parkin co-regulated protein Ribosomal_S15 PF00312.17 KNZ81654.1 - 2.4e-10 40.0 0.7 4.8e-10 39.0 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 NGP1NT PF08153.7 KNZ81655.1 - 5e-46 155.8 1.2 6.2e-46 155.5 0.0 1.7 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KNZ81655.1 - 8.7e-20 70.8 0.0 1.5e-15 57.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KNZ81655.1 - 4.8e-05 22.8 0.0 0.014 14.8 0.0 3.0 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KNZ81655.1 - 0.00014 21.1 0.2 0.00055 19.2 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KNZ81655.1 - 0.00026 20.2 0.0 0.00051 19.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KNZ81655.1 - 0.0031 17.3 0.8 2.2 8.1 0.1 3.6 2 1 1 3 3 3 1 Dynamin family Arf PF00025.16 KNZ81655.1 - 0.016 14.4 0.0 0.22 10.7 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Enolase_C PF00113.17 KNZ81656.1 - 2.8e-149 496.0 0.1 3.7e-149 495.5 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KNZ81656.1 - 1.6e-53 180.1 0.1 2.7e-53 179.4 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 KNZ81656.1 - 1e-05 25.4 0.0 3.8e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 KNZ81656.1 - 0.00037 19.5 0.2 0.00088 18.2 0.1 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 KNZ81656.1 - 0.02 15.3 0.0 0.043 14.3 0.0 1.6 1 1 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain RabGAP-TBC PF00566.13 KNZ81658.1 - 2.8e-44 151.1 0.0 3.7e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain rve PF00665.21 KNZ81660.1 - 1.3e-09 38.2 0.0 1.3e-09 38.2 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain MMS22L_N PF14910.1 KNZ81660.1 - 0.0054 15.0 0.2 0.0059 14.9 0.2 1.0 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, N-terminal Rotamase PF00639.16 KNZ81662.1 - 3.6e-24 85.3 0.0 5e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KNZ81662.1 - 2.1e-19 69.9 0.0 2.7e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KNZ81662.1 - 2.4e-06 27.2 0.3 5e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 KNZ81662.1 - 6.7e-05 23.5 0.0 8.9e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain MOSC_N PF03476.11 KNZ81663.1 - 5.2e-16 58.4 0.0 1.4e-15 57.0 0.0 1.7 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KNZ81663.1 - 7.1e-12 44.9 0.0 1.3e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 MOSC domain UCH PF00443.24 KNZ81664.1 - 9.4e-56 188.8 0.0 1.4e-55 188.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KNZ81664.1 - 7.9e-29 101.0 2.7 2.2e-21 76.6 0.2 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Urm1 PF09138.6 KNZ81665.1 - 1.7e-37 127.4 0.1 1.9e-37 127.2 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KNZ81665.1 - 0.00011 22.4 0.1 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 ThiS family ADH_zinc_N PF00107.21 KNZ81666.1 - 6.4e-29 100.1 0.0 1e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KNZ81666.1 - 1.5e-12 48.5 0.2 3.6e-12 47.2 0.0 1.7 2 1 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KNZ81666.1 - 5.6e-08 32.5 0.0 3.9e-07 29.7 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Y_phosphatase PF00102.22 KNZ81667.1 - 7.1e-42 143.3 0.0 2.2e-22 79.5 0.0 3.1 3 0 0 3 3 3 3 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KNZ81667.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 KNZ81667.1 - 0.0066 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KNZ81667.1 - 0.038 14.2 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Vps51 PF08700.6 KNZ81668.1 - 8.6e-16 57.5 2.2 8.6e-16 57.5 1.6 2.1 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 KNZ81668.1 - 1.9e-09 37.5 0.7 1.9e-09 37.5 0.5 1.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec3-PIP2_bind PF15277.1 KNZ81668.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH DUF3542 PF12061.3 KNZ81668.1 - 0.13 11.2 0.9 3.8 6.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3542) efThoc1 PF11957.3 KNZ81669.1 - 2.3e-94 316.6 0.2 5.8e-89 298.8 0.0 2.1 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Epimerase PF01370.16 KNZ81669.1 - 4.4e-28 98.3 0.0 7.1e-26 91.0 0.0 2.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KNZ81669.1 - 1.8e-23 82.2 0.1 5e-23 80.8 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Methyltransf_18 PF12847.2 KNZ81669.1 - 0.0018 18.8 0.0 0.22 12.1 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain RmlD_sub_bind PF04321.12 KNZ81669.1 - 0.0023 16.8 0.0 0.0065 15.3 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KNZ81669.1 - 0.0051 15.5 0.0 0.017 13.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KNZ81669.1 - 0.018 14.7 0.0 0.045 13.4 0.0 1.7 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.7 KNZ81669.1 - 0.047 12.6 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein adh_short PF00106.20 KNZ81669.1 - 0.067 13.0 0.0 0.17 11.7 0.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase F5_F8_type_C PF00754.20 KNZ81670.1 - 0.0003 20.6 0.0 0.00039 20.2 0.0 1.4 1 1 0 1 1 1 1 F5/8 type C domain APC10 PF03256.11 KNZ81670.1 - 0.028 14.0 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) UCH PF00443.24 KNZ81671.1 - 1e-44 152.6 0.0 2.1e-44 151.6 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KNZ81671.1 - 3.5e-25 87.1 0.0 6.5e-21 73.5 0.1 2.8 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.1 KNZ81671.1 - 2.9e-16 59.7 0.7 2.1e-09 37.2 0.1 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase APG6 PF04111.7 KNZ81671.1 - 0.24 10.4 1.9 0.2 10.6 0.2 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 DNA_methylase PF00145.12 KNZ81672.1 - 1.4e-37 129.6 0.0 5.7e-37 127.5 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.3 KNZ81672.1 - 7.2e-17 61.4 0.1 1.4e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.13 KNZ81672.1 - 8.2e-16 57.8 0.1 6.9e-09 35.4 0.0 2.8 2 0 0 2 2 2 2 BAH domain NAD_binding_1 PF00175.16 KNZ81673.1 - 5.1e-23 81.7 0.0 8.4e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KNZ81673.1 - 1.7e-19 69.7 0.0 3.6e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KNZ81673.1 - 3.5e-06 26.9 0.0 0.0013 18.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KNZ81673.1 - 0.041 13.8 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Pkinase PF00069.20 KNZ81674.1 - 3.9e-63 213.0 0.0 4.8e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81674.1 - 2.9e-25 88.8 0.0 3.8e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ81674.1 - 0.00024 20.9 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KNZ81674.1 - 0.0026 16.6 0.6 0.0039 16.0 0.4 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 KNZ81674.1 - 0.025 13.6 0.1 0.065 12.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KNZ81674.1 - 0.039 12.9 0.0 0.11 11.3 0.0 1.7 1 1 1 2 2 2 0 Kinase-like RIO1 PF01163.17 KNZ81674.1 - 0.043 13.1 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Hemerythrin PF01814.18 KNZ81675.1 - 0.00031 20.8 2.5 0.00063 19.9 0.5 2.1 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain DUF3474 PF11960.3 KNZ81675.1 - 0.036 14.1 0.8 0.062 13.3 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3474) zf-met PF12874.2 KNZ81677.1 - 3.5e-09 36.5 38.4 0.064 13.4 0.4 7.2 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KNZ81677.1 - 1.6e-08 34.4 46.9 0.089 13.1 0.7 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ81677.1 - 2.4e-08 33.7 40.8 0.039 14.2 0.2 7.4 6 1 1 7 7 7 5 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KNZ81677.1 - 0.00029 20.8 26.3 0.088 12.9 0.3 4.1 2 2 2 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KNZ81677.1 - 0.00044 20.3 44.0 0.15 12.2 2.0 6.6 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KNZ81677.1 - 0.022 14.6 32.0 0.11 12.4 0.5 5.7 6 0 0 6 6 6 0 C2H2-type zinc finger Lsr2 PF11774.3 KNZ81678.1 - 1.4 8.8 6.5 0.54 10.2 2.4 1.7 2 0 0 2 2 2 0 Lsr2 DUF3391 PF11871.3 KNZ81678.1 - 2.8 8.1 7.0 1 9.5 3.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) F-box-like PF12937.2 KNZ81679.1 - 0.00013 21.6 0.2 0.00065 19.3 0.0 2.3 2 1 0 2 2 2 1 F-box-like UBN2_2 PF14227.1 KNZ81680.1 - 6e-09 35.4 0.1 9.2e-09 34.8 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ81680.1 - 4.8e-07 29.5 0.1 6.7e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HECA PF15353.1 KNZ81680.1 - 0.047 13.4 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Headcase protein family homologue zf-CCHC PF00098.18 KNZ81680.1 - 0.1 12.5 0.3 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Sel1 PF08238.7 KNZ81681.1 - 5.7e-36 122.1 15.8 8.6e-09 35.7 0.1 6.1 6 0 0 6 6 6 5 Sel1 repeat DNA_pol_A_exo1 PF01612.15 KNZ81683.1 - 3.5e-06 26.6 0.1 0.00015 21.3 0.2 2.3 1 1 1 2 2 2 2 3'-5' exonuclease Sld5 PF05916.6 KNZ81686.1 - 0.0021 18.2 0.0 0.0047 17.2 0.0 1.7 2 1 0 2 2 2 1 GINS complex protein NurA PF09376.5 KNZ81686.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 NurA domain PPR PF01535.15 KNZ81687.1 - 0.0017 18.2 0.4 9.1 6.5 0.0 4.2 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.1 KNZ81687.1 - 0.014 15.6 1.0 0.76 10.2 0.0 3.3 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TPR_10 PF13374.1 KNZ81687.1 - 5.6 7.0 8.1 1.8 8.5 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.1 KNZ81688.1 - 0.0061 16.8 1.4 0.0061 16.8 1.0 2.0 2 0 0 2 2 2 1 Snapin/Pallidin Laminin_II PF06009.7 KNZ81688.1 - 0.062 13.0 5.8 0.23 11.2 3.4 2.4 2 1 0 2 2 2 0 Laminin Domain II DUF1320 PF07030.7 KNZ81688.1 - 0.12 12.0 4.1 0.23 11.1 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) TraF_2 PF13729.1 KNZ81688.1 - 0.15 10.8 3.5 1.7 7.3 0.4 2.9 2 1 0 3 3 3 0 F plasmid transfer operon, TraF, protein Spc7 PF08317.6 KNZ81688.1 - 0.17 10.5 9.0 0.18 10.4 5.5 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 KNZ81688.1 - 0.18 11.3 12.3 0.53 9.8 0.7 2.6 3 0 0 3 3 3 0 IncA protein tRNA-synt_1e PF01406.14 KNZ81688.1 - 0.19 10.8 1.1 0.46 9.5 0.7 1.6 2 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF972 PF06156.8 KNZ81688.1 - 0.21 11.9 6.3 0.25 11.6 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 KNZ81688.1 - 0.34 10.7 10.5 0.082 12.7 4.9 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.6 KNZ81688.1 - 0.41 10.5 2.7 1.9 8.4 1.4 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) COG2 PF06148.6 KNZ81688.1 - 0.59 10.0 8.6 1.3 8.9 2.8 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.14 KNZ81688.1 - 0.71 7.6 6.5 0.23 9.2 2.2 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 KNZ81688.1 - 0.8 9.7 10.8 1.6 8.7 2.3 3.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 KNZ81688.1 - 0.92 8.4 7.7 0.075 12.0 1.4 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF367 PF04034.8 KNZ81689.1 - 2.6e-45 153.1 0.0 3.5e-45 152.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KNZ81689.1 - 3.3e-14 52.1 0.1 5.5e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI PfkB PF00294.19 KNZ81690.1 - 5e-23 81.6 0.0 1.8e-22 79.8 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase SeqA PF03925.8 KNZ81690.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 SeqA protein Ribosomal_L16 PF00252.13 KNZ81691.1 - 7.7e-33 113.0 0.1 9.6e-33 112.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Kinesin PF00225.18 KNZ81692.1 - 1e-93 313.6 0.2 1.8e-93 312.8 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain TPR_2 PF07719.12 KNZ81692.1 - 0.0028 17.4 0.1 0.0053 16.5 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ81692.1 - 0.01 15.7 0.1 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ81692.1 - 0.013 16.0 0.1 0.039 14.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ81692.1 - 0.016 14.9 0.1 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Cytochrom_B561 PF03188.11 KNZ81693.1 - 2.2e-11 43.7 12.2 3.1e-11 43.2 8.5 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KNZ81693.1 - 0.0092 15.5 3.6 0.0092 15.5 2.5 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF2427) DUF872 PF05915.7 KNZ81693.1 - 0.05 13.4 3.6 2.6 7.9 1.2 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SdpI PF13630.1 KNZ81693.1 - 1.6 8.5 13.9 0.055 13.1 1.8 3.0 1 1 2 3 3 3 0 SdpI/YhfL protein family Ni_hydr_CYTB PF01292.15 KNZ81693.1 - 7.7 5.8 19.3 2.3e+02 1.0 13.4 2.7 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF1471 PF07338.8 KNZ81694.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Synaptobrevin PF00957.16 KNZ81695.1 - 1.2 8.7 7.4 0.15 11.6 0.4 3.1 3 0 0 3 3 3 0 Synaptobrevin Pkinase PF00069.20 KNZ81696.1 - 4.3e-73 245.6 0.0 7e-73 244.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81696.1 - 3.1e-44 151.0 0.0 5.4e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 KNZ81696.1 - 5.5e-33 112.7 0.3 2.3e-21 75.5 0.1 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 KNZ81696.1 - 1.6e-08 33.8 0.4 9.1e-08 31.3 0.0 2.3 3 0 0 3 3 3 1 Kinase-like DUF4520 PF15016.1 KNZ81696.1 - 0.0025 17.3 0.0 0.0067 15.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4520) APH PF01636.18 KNZ81696.1 - 0.0067 16.1 0.3 0.36 10.5 0.3 2.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Melibiase PF02065.13 KNZ81697.1 - 7.3e-15 54.5 0.2 1.4e-10 40.4 0.0 2.9 2 1 0 2 2 2 2 Melibiase WD40 PF00400.27 KNZ81698.1 - 2.4e-69 226.9 16.5 1.9e-10 40.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KNZ81698.1 - 1.9e-21 76.0 1.6 3.4e-21 75.2 1.1 1.4 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 KNZ81698.1 - 0.0002 19.6 0.7 0.047 11.8 0.0 3.3 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KNZ81698.1 - 0.00035 18.9 0.9 0.0037 15.6 0.2 2.8 2 1 0 2 2 2 1 Cytochrome D1 heme domain HALZ PF02183.13 KNZ81698.1 - 0.00042 19.9 0.5 0.028 14.1 0.0 2.4 2 0 0 2 2 2 1 Homeobox associated leucine zipper Nbas_N PF15492.1 KNZ81698.1 - 0.0034 16.5 0.2 6.6 5.7 0.0 3.5 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 KNZ81698.1 - 0.032 13.9 4.6 26 4.6 0.0 6.2 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Spc7 PF08317.6 KNZ81698.1 - 0.079 11.6 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Proteasome_A_N PF10584.4 KNZ81698.1 - 0.28 10.5 0.9 53 3.2 0.1 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature IncA PF04156.9 KNZ81698.1 - 0.7 9.4 7.7 1.5 8.3 5.4 1.5 1 1 0 1 1 1 0 IncA protein DUF1777 PF08648.7 KNZ81698.1 - 1.5 8.5 34.9 2.7 7.7 24.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) APG6 PF04111.7 KNZ81698.1 - 4.6 6.1 5.3 0.51 9.3 0.1 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF2956 PF11169.3 KNZ81698.1 - 8.9 6.3 6.8 18 5.3 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) adh_short_C2 PF13561.1 KNZ81699.1 - 1.6e-24 87.0 0.0 2.3e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KNZ81699.1 - 1.8e-24 86.5 0.5 2.5e-24 86.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ81699.1 - 1.9e-11 43.9 0.2 3.3e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 KR domain CotJB PF12652.2 KNZ81701.1 - 0.1 12.6 0.3 6.4 6.9 0.0 2.4 2 0 0 2 2 2 0 CotJB protein MFS_1 PF07690.11 KNZ81702.1 - 1e-21 77.0 38.2 1.1e-15 57.2 8.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KNZ81702.1 - 0.046 13.7 6.6 1.7 8.7 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) 6PF2K PF01591.13 KNZ81703.1 - 8.4e-55 185.2 0.0 1.3e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KNZ81703.1 - 1.3e-19 70.8 0.0 1.3e-18 67.5 0.0 2.2 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KNZ81703.1 - 5.7e-08 32.7 0.0 2.6e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KNZ81703.1 - 9.3e-07 29.6 0.2 0.0045 17.7 0.1 2.7 2 1 0 2 2 2 2 AAA domain KTI12 PF08433.5 KNZ81703.1 - 0.0004 19.6 0.0 0.00084 18.6 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KNZ81703.1 - 0.043 12.8 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin tRNA_lig_kinase PF08303.6 KNZ81703.1 - 0.099 12.5 0.4 0.33 10.8 0.0 2.0 3 0 0 3 3 3 0 tRNA ligase kinase domain APS_kinase PF01583.15 KNZ81703.1 - 0.099 12.2 1.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA PF00004.24 KNZ81703.1 - 0.12 12.5 0.1 4.2 7.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RRM_5 PF13893.1 KNZ81704.1 - 0.00066 19.4 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KNZ81704.1 - 0.00088 19.6 0.1 0.0017 18.7 0.1 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.17 KNZ81704.1 - 0.023 14.3 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IFT20 PF14931.1 KNZ81705.1 - 0.012 15.5 0.6 0.032 14.1 0.0 1.9 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DDE_3 PF13358.1 KNZ81705.1 - 0.019 14.6 0.7 0.12 12.0 0.0 2.0 1 1 1 2 2 2 0 DDE superfamily endonuclease McrBC PF10117.4 KNZ81705.1 - 0.047 12.6 0.1 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component DUF2663 PF10864.3 KNZ81705.1 - 0.18 12.0 0.7 0.49 10.6 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2663) TPT PF03151.11 KNZ81706.1 - 6.5e-23 81.0 12.9 6.5e-23 81.0 8.9 1.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family DUF1118 PF06549.7 KNZ81706.1 - 0.5 10.5 9.1 0.067 13.3 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) LSM PF01423.17 KNZ81707.1 - 3.7e-13 48.8 0.0 5e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain RVP_2 PF08284.6 KNZ81708.1 - 0.009 15.9 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KNZ81708.1 - 0.048 13.4 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease adh_short PF00106.20 KNZ81710.1 - 1.2e-22 80.6 0.2 1.5e-22 80.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ81710.1 - 2.8e-06 27.1 0.0 3.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KNZ81710.1 - 1.8e-05 24.3 0.0 2.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KNZ81710.1 - 6.7e-05 22.1 0.0 9e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KNZ81710.1 - 0.00049 20.1 0.1 0.00089 19.3 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KNZ81710.1 - 0.0051 15.7 0.0 0.0081 15.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KNZ81710.1 - 0.0062 15.4 0.0 0.0092 14.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KNZ81710.1 - 0.0079 15.4 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family DUF2064 PF09837.4 KNZ81710.1 - 0.088 12.4 0.0 5.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) BCDHK_Adom3 PF10436.4 KNZ81711.1 - 2.6e-68 228.6 0.0 4.5e-68 227.8 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KNZ81711.1 - 7.6e-19 67.4 0.0 1.9e-18 66.2 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KNZ81711.1 - 0.0008 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyr_redox PF00070.22 KNZ81712.1 - 3.8e-12 46.4 0.1 8.4e-11 42.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KNZ81712.1 - 5.7e-11 42.6 0.0 8.9e-11 42.0 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNZ81712.1 - 1.4e-05 25.2 0.0 0.00027 21.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNZ81712.1 - 8.7e-05 22.3 0.2 0.0081 15.9 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 KNZ81712.1 - 0.00039 20.6 0.0 0.54 10.5 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding PGAP1 PF07819.8 KNZ81712.1 - 0.0065 16.0 0.3 0.013 15.1 0.2 1.4 1 0 0 1 1 1 1 PGAP1-like protein K_oxygenase PF13434.1 KNZ81712.1 - 0.0078 15.1 0.0 0.56 9.0 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 KNZ81712.1 - 0.06 12.2 0.1 24 3.6 0.1 2.9 2 1 1 3 3 3 0 Lycopene cyclase protein PITH PF06201.8 KNZ81713.1 - 3.7e-37 127.4 0.0 4.5e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain Ribosomal_S5_C PF03719.10 KNZ81714.1 - 1.4e-18 65.8 0.0 4.1e-18 64.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KNZ81714.1 - 1.6e-13 50.1 0.4 4e-13 48.8 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Fe-ADH PF00465.14 KNZ81714.1 - 0.43 9.1 1.6 3.2 6.3 0.1 2.2 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase Pkinase PF00069.20 KNZ81715.1 - 8.2e-52 175.9 0.0 1.2e-51 175.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81715.1 - 2e-24 86.0 0.0 2.7e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KNZ81715.1 - 0.00059 18.8 0.0 0.0033 16.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 KNZ81715.1 - 0.0042 15.9 0.1 0.0042 15.9 0.1 1.4 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase APH PF01636.18 KNZ81715.1 - 0.0062 16.2 0.1 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Macoilin PF09726.4 KNZ81716.1 - 0.31 9.2 4.2 0.43 8.7 2.9 1.1 1 0 0 1 1 1 0 Transmembrane protein BUD22 PF09073.5 KNZ81717.1 - 0.032 13.3 5.9 0.045 12.8 4.1 1.1 1 0 0 1 1 1 0 BUD22 Hid1 PF12722.2 KNZ81717.1 - 0.091 10.4 2.4 0.11 10.0 1.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MAM PF00629.18 KNZ81718.1 - 0.032 14.0 0.4 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 MAM domain MR_MLE_C PF13378.1 KNZ81719.1 - 1.9e-16 60.0 0.1 4.5e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KNZ81719.1 - 1.5e-11 44.6 0.0 4e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KNZ81719.1 - 1e-06 28.7 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 KNZ81719.1 - 0.01 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Peptidase_C25_C PF03785.9 KNZ81719.1 - 0.14 11.9 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain Herpes_Helicase PF02689.9 KNZ81721.1 - 5.5e-06 24.4 0.0 5.8e-06 24.3 0.0 1.0 1 0 0 1 1 1 1 Helicase Velvet PF11754.3 KNZ81723.1 - 1.7e-54 184.5 1.1 6.1e-37 127.2 0.0 2.5 2 0 0 2 2 2 2 Velvet factor HNH_2 PF13391.1 KNZ81723.1 - 1.1e-07 31.4 0.1 2e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease NAD_binding_10 PF13460.1 KNZ81724.1 - 1.1e-20 74.4 0.0 1.4e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding EF1G PF00647.14 KNZ81725.1 - 3.1e-17 62.2 0.7 8.9e-14 51.0 0.0 2.4 1 1 1 2 2 2 2 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 KNZ81725.1 - 1.1e-10 41.5 0.0 2.3e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KNZ81725.1 - 1.1e-08 34.8 0.0 2.3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KNZ81725.1 - 2.1e-08 34.0 0.1 8.5e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KNZ81725.1 - 8.6e-07 29.3 0.1 2.8e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KNZ81725.1 - 5.3e-06 26.5 0.0 1.7e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KNZ81725.1 - 0.0035 17.3 0.0 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Rotamase PF00639.16 KNZ81725.1 - 0.052 14.2 0.0 0.12 13.1 0.0 1.6 1 0 0 1 1 1 0 PPIC-type PPIASE domain SKG6 PF08693.5 KNZ81726.1 - 7.8 5.9 5.9 4.6 6.6 2.0 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain GPI-anchored PF10342.4 KNZ81727.1 - 2.2e-08 34.4 0.3 6.9e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AA_permease_2 PF13520.1 KNZ81728.1 - 1.8e-32 112.4 47.9 2.2e-32 112.1 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KNZ81728.1 - 7e-16 57.6 46.3 1.2e-15 56.8 32.1 1.3 1 1 0 1 1 1 1 Amino acid permease Pox_F11 PF04943.7 KNZ81729.1 - 0.035 12.9 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein Imm35 PF15581.1 KNZ81729.1 - 0.051 13.6 0.1 0.13 12.3 0.0 1.7 1 1 1 2 2 2 0 Immunity protein 35 DUF2383 PF09537.5 KNZ81729.1 - 0.071 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) RNase_H PF00075.19 KNZ81730.1 - 2.4e-13 50.5 0.0 5e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 KNZ81731.1 - 3.8e-19 68.4 0.2 9.8e-19 67.1 0.1 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 KNZ81731.1 - 0.00021 20.7 0.0 0.0015 17.9 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 KNZ81731.1 - 0.0015 18.5 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AA_permease_2 PF13520.1 KNZ81732.1 - 6.4e-34 117.2 56.2 9e-34 116.7 38.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KNZ81732.1 - 6.4e-17 61.0 48.9 9.2e-17 60.5 33.9 1.2 1 0 0 1 1 1 1 Amino acid permease PIF1 PF05970.9 KNZ81733.1 - 9.2e-31 107.0 0.0 1e-30 106.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.9 KNZ81734.1 - 3e-18 65.9 0.1 3.4e-18 65.7 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ81734.1 - 0.066 12.7 0.0 0.066 12.7 0.0 1.0 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 KNZ81734.1 - 0.13 12.1 0.1 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Torsin Helitron_like_N PF14214.1 KNZ81735.1 - 1.4e-09 37.9 0.1 1.8e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ81735.1 - 0.093 12.2 0.0 0.099 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) Rootletin PF15035.1 KNZ81738.1 - 0.025 14.5 0.5 0.025 14.5 0.4 3.2 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF1492 PF07374.6 KNZ81738.1 - 0.052 13.6 0.7 0.18 11.9 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) PIF1 PF05970.9 KNZ81741.1 - 5.4e-24 84.8 0.0 6.3e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase SAD_SRA PF02182.12 KNZ81742.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 SAD/SRA domain CBP4 PF07960.6 KNZ81743.1 - 0.008 15.7 0.0 0.0095 15.5 0.0 1.1 1 0 0 1 1 1 1 CBP4 Ycf54 PF10674.4 KNZ81743.1 - 0.034 14.2 0.1 0.039 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) TauD PF02668.11 KNZ81744.1 - 7.8e-55 186.3 0.2 9.9e-55 185.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GATA PF00320.22 KNZ81745.1 - 8.7e-15 53.7 4.1 1.7e-14 52.8 2.8 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1295 PF06966.7 KNZ81747.1 - 4.5e-12 45.7 0.0 5.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 KNZ81747.1 - 1.5e-10 40.2 0.5 2.1e-10 39.7 0.3 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.11 KNZ81747.1 - 2.5e-07 30.6 0.0 3.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 KNZ81747.1 - 0.033 14.3 0.1 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 Phospholipid methyltransferase Med22 PF06179.7 KNZ81748.1 - 1e-15 57.6 1.6 1.4e-15 57.2 1.1 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PMC2NT PF08066.7 KNZ81748.1 - 0.0018 18.5 5.2 0.054 13.7 0.4 2.2 1 1 1 2 2 2 2 PMC2NT (NUC016) domain MIR PF02815.14 KNZ81748.1 - 0.11 12.0 0.1 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 MIR domain IncA PF04156.9 KNZ81749.1 - 0.13 11.8 2.7 0.3 10.6 1.5 1.7 2 0 0 2 2 2 0 IncA protein DUF1664 PF07889.7 KNZ81749.1 - 0.25 11.1 1.7 9 6.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 KNZ81749.1 - 5.3 6.8 9.3 0.49 10.2 2.5 2.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OPT PF03169.10 KNZ81750.1 - 1.3e-138 463.1 23.2 1.5e-138 463.0 16.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.3 KNZ81750.1 - 0.015 15.0 1.5 0.041 13.6 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Actin PF00022.14 KNZ81752.1 - 1.1e-40 139.2 0.0 2.7e-35 121.5 0.0 2.7 2 1 0 2 2 2 2 Actin DUF3669 PF12417.3 KNZ81753.1 - 4.5e-08 32.7 0.2 9.1e-08 31.7 0.1 1.5 1 0 0 1 1 1 1 Zinc finger protein Mito_carr PF00153.22 KNZ81754.1 - 1.8e-41 139.7 3.7 4.9e-24 83.8 0.3 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein Methyltransf_16 PF10294.4 KNZ81755.1 - 4.6e-16 58.7 0.0 8.1e-16 57.9 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase Herpes_UL74 PF07982.7 KNZ81755.1 - 0.088 11.4 0.3 0.16 10.5 0.0 1.5 2 0 0 2 2 2 0 Herpes UL74 glycoproteins Methyltransf_26 PF13659.1 KNZ81755.1 - 0.12 12.3 0.0 0.88 9.6 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain PCMT PF01135.14 KNZ81755.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Mitofilin PF09731.4 KNZ81757.1 - 2.7e-116 389.5 2.0 3.3e-116 389.2 1.4 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Rabaptin PF03528.10 KNZ81757.1 - 0.36 10.7 16.8 0.55 10.1 11.0 1.9 1 1 0 1 1 1 0 Rabaptin FadA PF09403.5 KNZ81757.1 - 0.78 9.7 12.7 0.098 12.6 5.5 1.9 2 0 0 2 2 2 0 Adhesion protein FadA DUF2894 PF11445.3 KNZ81757.1 - 0.99 9.6 9.8 0.7 10.1 5.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2894) DUF2937 PF11157.3 KNZ81757.1 - 3.2 7.0 6.8 5.4 6.3 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) USP8_interact PF08941.5 KNZ81758.1 - 0.001 18.4 0.0 0.0022 17.3 0.0 1.5 1 0 0 1 1 1 1 USP8 interacting Nucleoporin_FG PF13634.1 KNZ81759.1 - 3.7e-34 117.3 179.6 8.4e-12 45.3 27.1 4.5 2 1 3 5 5 5 4 Nucleoporin FG repeat region DUF427 PF04248.7 KNZ81759.1 - 1.1e-33 114.6 0.1 5.9e-27 93.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF427) ATP-synt_B PF00430.13 KNZ81763.1 - 0.15 11.8 0.6 0.22 11.3 0.4 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Fe_dep_repr_C PF02742.10 KNZ81765.1 - 0.085 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain DUF202 PF02656.10 KNZ81767.1 - 8.8e-09 35.4 4.7 8.8e-09 35.4 3.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2776 PF10951.3 KNZ81767.1 - 0.03 13.3 0.1 0.039 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) DUF1182 PF06681.8 KNZ81767.1 - 0.074 12.2 0.2 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) DUF4131 PF13567.1 KNZ81767.1 - 0.096 12.0 1.1 0.14 11.5 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3649 PF12365.3 KNZ81767.1 - 0.63 9.6 6.9 0.31 10.5 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) CTDII PF01556.13 KNZ81768.1 - 3.1e-18 65.4 0.2 9.2e-18 63.9 0.1 1.8 2 1 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.26 KNZ81768.1 - 1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain RCC1 PF00415.13 KNZ81769.1 - 5.4e-20 71.3 3.1 3.8e-05 23.8 0.0 5.7 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KNZ81769.1 - 2.3e-16 59.7 0.0 6.4e-07 29.3 0.0 2.9 2 1 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.1 KNZ81769.1 - 3.4e-08 32.8 12.0 1.5e-07 30.8 0.0 5.0 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.1 KNZ81769.1 - 1.3e-07 31.6 5.1 0.0052 17.0 0.5 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KNZ81769.1 - 7.7e-06 26.1 0.0 2.3e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KNZ81769.1 - 1.6e-05 24.6 0.7 0.33 11.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KNZ81769.1 - 0.00013 22.4 1.3 0.00052 20.4 0.2 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KNZ81769.1 - 0.0097 15.6 0.8 1.5 8.8 0.1 3.0 2 0 0 2 2 2 1 Ankyrin repeat eIF3_subunit PF08597.5 KNZ81770.1 - 2.6e-51 174.5 19.2 2.9e-51 174.4 13.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit COQ9 PF08511.6 KNZ81771.1 - 7.4e-08 31.7 0.0 1.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 COQ9 Aa_trans PF01490.13 KNZ81773.1 - 4.4e-24 84.7 22.7 7.9e-24 83.8 15.8 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UBACT PF02134.16 KNZ81773.1 - 0.089 12.3 0.6 0.19 11.3 0.4 1.5 1 0 0 1 1 1 0 Repeat in ubiquitin-activating (UBA) protein Glyco_hydro_cc PF11790.3 KNZ81775.1 - 1.2e-47 162.3 0.2 1.6e-47 161.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core GTA_TIM PF13547.1 KNZ81775.1 - 0.012 14.6 0.1 0.053 12.5 0.1 1.9 2 0 0 2 2 2 0 GTA TIM-barrel-like domain Complex1_LYR PF05347.10 KNZ81776.1 - 1.1e-07 31.4 0.3 1.1e-07 31.4 0.2 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KNZ81776.1 - 2.1e-06 27.8 0.1 2.1e-06 27.8 0.1 2.5 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KNZ81776.1 - 0.00067 20.0 0.7 0.00067 20.0 0.5 2.3 1 1 1 2 2 2 1 Complex1_LYR-like DUF4326 PF14216.1 KNZ81776.1 - 3 8.4 5.1 2 9.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4326) ERG4_ERG24 PF01222.12 KNZ81777.1 - 5.8e-125 417.2 20.8 1.5e-122 409.2 14.4 2.0 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KNZ81777.1 - 1.5e-06 27.6 0.4 1.5e-06 27.6 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KNZ81777.1 - 1.8e-06 27.9 0.1 1.8e-06 27.9 0.0 3.2 4 0 0 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.9 KNZ81777.1 - 5.3e-05 23.3 0.1 0.00084 19.4 0.0 2.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF4515 PF14988.1 KNZ81778.1 - 0.08 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Citrate_synt PF00285.16 KNZ81779.1 - 1.2e-116 389.3 0.0 1.4e-116 389.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase DUF4614 PF15391.1 KNZ81780.1 - 0.076 12.7 10.5 0.11 12.2 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Pap_E4 PF02711.9 KNZ81780.1 - 0.14 13.0 3.9 1 10.2 2.5 2.2 2 0 0 2 2 2 0 E4 protein Peptidase_S21 PF00716.12 KNZ81780.1 - 0.21 10.8 8.0 0.27 10.5 5.6 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) DUF572 PF04502.8 KNZ81780.1 - 1.8 7.7 4.1 2 7.5 2.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DNA_pol_viral_N PF00242.12 KNZ81780.1 - 5.2 5.9 7.0 5.9 5.8 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF515 PF04415.7 KNZ81780.1 - 6.1 4.9 15.3 8.5 4.5 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pcc1 PF09341.5 KNZ81781.1 - 8.9e-18 64.1 0.9 1e-17 63.9 0.6 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 AAA-ATPase_like PF09820.4 KNZ81782.1 - 5e-47 160.4 0.0 8.4e-47 159.6 0.0 1.3 1 0 0 1 1 1 1 Predicted AAA-ATPase DUF1703 PF08011.6 KNZ81782.1 - 3.4e-08 33.1 0.0 5.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1703) Lon_C PF05362.8 KNZ81783.1 - 2.9e-33 114.9 0.1 6.1e-33 113.8 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 KNZ81783.1 - 4e-20 72.3 0.0 6.7e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KNZ81783.1 - 6.3e-09 35.6 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KNZ81783.1 - 0.0005 20.0 0.0 0.0021 18.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KNZ81783.1 - 0.0017 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KNZ81783.1 - 0.0021 17.1 0.0 0.13 11.3 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 KNZ81783.1 - 0.0022 17.5 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KNZ81783.1 - 0.0028 16.4 0.2 0.027 13.1 0.1 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 KNZ81783.1 - 0.0041 16.5 0.0 0.012 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ81783.1 - 0.0043 17.8 0.0 0.016 15.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KNZ81783.1 - 0.0047 17.0 0.1 0.17 12.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KNZ81783.1 - 0.034 14.0 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KNZ81783.1 - 0.039 13.5 0.1 0.09 12.4 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ClpB_D2-small PF10431.4 KNZ81783.1 - 0.08 12.8 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein Parvo_NS1 PF01057.12 KNZ81783.1 - 0.089 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.1 KNZ81783.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KNZ81783.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PPV_E1_C PF00519.12 KNZ81783.1 - 0.22 10.0 0.0 0.37 9.3 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Peptidase_M24 PF00557.19 KNZ81784.1 - 4.8e-22 78.5 0.4 6.7e-22 78.0 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Methyltransf_18 PF12847.2 KNZ81786.1 - 1.3e-10 41.7 0.0 2.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ81786.1 - 1.3e-08 35.1 0.0 5.6e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ81786.1 - 3.4e-08 33.2 0.0 6.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KNZ81786.1 - 3.1e-07 29.7 0.0 5.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KNZ81786.1 - 9e-06 25.7 0.0 5.6e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ81786.1 - 1.4e-05 24.8 0.0 5.5e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ81786.1 - 1.5e-05 25.2 0.0 2.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ81786.1 - 0.0001 21.7 0.0 0.00025 20.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KNZ81786.1 - 0.00029 19.9 0.0 0.0013 17.8 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 KNZ81786.1 - 0.0006 20.2 0.0 0.0021 18.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KNZ81786.1 - 0.0039 17.1 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase NDUF_B8 PF05821.6 KNZ81787.1 - 2.1e-06 27.5 0.0 2.5e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Mgr1 PF08602.5 KNZ81787.1 - 0.089 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit PH PF00169.24 KNZ81788.1 - 0.0015 18.6 0.0 0.034 14.3 0.0 2.8 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 KNZ81788.1 - 0.0082 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Prothymosin PF03247.9 KNZ81788.1 - 0.48 10.5 16.9 0.095 12.8 8.7 2.0 2 0 0 2 2 2 0 Prothymosin/parathymosin family RXT2_N PF08595.6 KNZ81788.1 - 0.62 9.8 6.8 1.5 8.6 4.7 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 KNZ81788.1 - 1.3 8.1 7.6 2.2 7.4 5.3 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 KNZ81788.1 - 2.2 8.5 11.2 5.7 7.2 7.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BTV_NS2 PF04514.7 KNZ81788.1 - 6.2 5.6 8.4 12 4.6 5.8 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 XPG_N PF00752.12 KNZ81789.1 - 6.1e-29 100.2 0.0 1.5e-28 99.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KNZ81789.1 - 1.2e-26 92.5 0.0 3.6e-26 91.0 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 KNZ81789.1 - 0.00063 19.3 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing OGFr_N PF04664.8 KNZ81789.1 - 0.016 14.5 0.1 0.04 13.2 0.0 1.6 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region 5_3_exonuc PF01367.15 KNZ81789.1 - 0.03 14.5 0.0 0.41 10.8 0.0 2.7 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold CtaG_Cox11 PF04442.9 KNZ81790.1 - 3.1e-57 192.6 0.0 3.9e-57 192.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DnaJ PF00226.26 KNZ81791.1 - 9.2e-17 60.5 1.1 9.2e-17 60.5 0.7 1.9 2 0 0 2 2 2 1 DnaJ domain DUF1767 PF08585.7 KNZ81792.1 - 7.4e-05 22.9 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Carn_acyltransf PF00755.15 KNZ81793.1 - 9.6e-124 413.6 0.0 1.1e-123 413.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AAA_12 PF13087.1 KNZ81794.1 - 1e-34 119.6 0.0 2.3e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KNZ81794.1 - 8.9e-24 84.3 2.6 5.1e-11 42.5 0.1 2.9 2 1 0 3 3 3 2 AAA domain AAA_30 PF13604.1 KNZ81794.1 - 1.4e-11 44.3 0.0 6.7e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNZ81794.1 - 8.3e-10 38.2 0.0 2.9e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 KNZ81794.1 - 0.00056 19.7 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KNZ81794.1 - 0.00059 18.9 0.2 0.019 13.9 0.0 2.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KNZ81794.1 - 0.00069 19.2 0.5 1.3 8.4 0.0 3.3 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 KNZ81794.1 - 0.00078 19.1 0.0 0.0024 17.5 0.0 1.8 1 1 0 1 1 1 1 Helicase PhoH PF02562.11 KNZ81794.1 - 0.0054 15.9 0.0 0.37 9.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein UvrD-helicase PF00580.16 KNZ81794.1 - 0.013 14.8 0.8 4.3 6.5 0.0 2.6 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 KNZ81794.1 - 0.015 15.2 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KNZ81794.1 - 0.025 14.7 0.0 0.2 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KNZ81794.1 - 0.064 13.7 0.0 1.4 9.4 0.0 2.8 3 0 0 3 3 3 0 Miro-like protein AAA PF00004.24 KNZ81794.1 - 0.093 12.9 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KNZ81794.1 - 0.099 12.5 0.0 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_12 PF13087.1 KNZ81795.1 - 9.9e-32 109.9 0.0 2.7e-31 108.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KNZ81795.1 - 1.8e-29 102.9 2.0 4.5e-15 55.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 KNZ81795.1 - 5.3e-15 55.5 0.0 3.2e-14 52.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNZ81795.1 - 5.9e-13 48.3 0.0 8.5e-12 44.6 0.0 2.9 4 0 0 4 4 2 1 Part of AAA domain Helicase_RecD PF05127.9 KNZ81795.1 - 0.00032 20.3 0.2 0.0026 17.4 0.1 2.3 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 KNZ81795.1 - 0.00033 20.2 0.0 0.08 12.4 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KNZ81795.1 - 0.00041 20.5 0.1 0.0034 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KNZ81795.1 - 0.00045 20.2 0.1 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain ResIII PF04851.10 KNZ81795.1 - 0.00075 19.3 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KNZ81795.1 - 0.00087 18.5 0.0 0.015 14.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.1 KNZ81795.1 - 0.0012 18.3 0.0 0.0028 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KNZ81795.1 - 0.0019 17.1 0.0 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 KNZ81795.1 - 0.0026 17.9 0.0 0.0055 16.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KNZ81795.1 - 0.003 17.0 0.0 0.0065 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KNZ81795.1 - 0.0041 17.9 0.1 0.016 16.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KNZ81795.1 - 0.0067 15.4 0.0 0.02 13.8 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 KNZ81795.1 - 0.0077 15.1 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.24 KNZ81795.1 - 0.0078 15.7 0.0 0.027 13.9 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 KNZ81795.1 - 0.0088 15.3 0.5 0.043 13.1 0.0 2.2 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_23 PF13476.1 KNZ81795.1 - 0.014 15.7 0.2 0.033 14.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 KNZ81795.1 - 0.015 15.2 0.3 0.068 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KNZ81795.1 - 0.021 14.0 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 KNZ81795.1 - 0.03 14.0 0.0 0.06 13.0 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase TIP49 PF06068.8 KNZ81795.1 - 0.049 12.3 0.7 0.19 10.3 0.0 2.2 3 0 0 3 3 3 0 TIP49 C-terminus KaiC PF06745.8 KNZ81795.1 - 0.054 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.13 KNZ81795.1 - 0.064 12.7 0.1 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.1 KNZ81795.1 - 0.074 12.6 0.6 0.27 10.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KNZ81795.1 - 0.097 12.3 0.4 0.74 9.5 0.1 2.5 2 0 0 2 2 2 0 NTPase AzlD PF05437.7 KNZ81795.1 - 0.12 12.3 0.1 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) Pam16 PF03656.8 KNZ81796.1 - 4.1e-06 26.6 0.0 5.2e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.26 KNZ81796.1 - 4.3e-05 23.1 0.0 6.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Methyltransf_18 PF12847.2 KNZ81797.1 - 5.6e-14 52.6 0.0 9.7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ81797.1 - 2e-12 46.9 0.0 2.8e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ81797.1 - 1.9e-08 34.3 0.0 4.5e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ81797.1 - 3.4e-08 33.8 0.0 6.3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ81797.1 - 5e-06 26.3 0.0 7.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ81797.1 - 7.4e-06 26.3 0.0 1.7e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ81797.1 - 0.00015 22.1 0.0 0.00026 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ81797.1 - 0.009 15.3 0.0 0.022 14.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KNZ81797.1 - 0.023 13.7 0.0 0.039 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MIF4G PF02854.14 KNZ81798.1 - 4.5e-23 81.7 1.4 7.4e-23 81.0 1.0 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 KNZ81798.1 - 4.8e-21 74.5 0.0 1.9e-20 72.6 0.0 2.1 2 0 0 2 2 2 1 MA3 domain AAT PF03417.11 KNZ81798.1 - 0.0077 15.6 0.1 0.093 12.1 0.0 2.1 2 0 0 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Pox_P35 PF03213.9 KNZ81798.1 - 0.031 13.2 0.0 0.086 11.8 0.0 1.7 1 0 0 1 1 1 0 Poxvirus P35 protein Svf1 PF08622.5 KNZ81799.1 - 3.8e-84 282.4 0.0 4.3e-84 282.2 0.0 1.0 1 0 0 1 1 1 1 Svf1-like GMC_oxred_N PF00732.14 KNZ81800.1 - 2e-57 194.5 0.0 1.4e-46 159.0 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ81800.1 - 4.4e-36 124.3 0.0 7.2e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KNZ81800.1 - 2.7e-07 29.8 0.0 1.6e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ81800.1 - 7.5e-07 28.3 0.1 0.0011 17.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KNZ81800.1 - 3.1e-05 23.0 0.0 4.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KNZ81800.1 - 0.00024 21.0 0.2 0.00071 19.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KNZ81800.1 - 0.00068 19.5 0.0 0.43 10.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KNZ81800.1 - 0.0011 19.1 0.0 0.33 10.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KNZ81800.1 - 0.0047 17.2 0.1 0.091 13.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KNZ81800.1 - 0.024 13.5 0.0 0.78 8.6 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KNZ81800.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 KNZ81800.1 - 0.093 12.4 0.0 0.21 11.3 0.0 1.7 1 1 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KNZ81800.1 - 0.096 11.7 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KNZ81800.1 - 0.13 10.7 0.1 0.25 9.7 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein GDI PF00996.13 KNZ81800.1 - 0.17 10.1 0.0 0.26 9.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_oxidored PF12831.2 KNZ81800.1 - 0.94 8.4 4.5 2.5 7.0 0.6 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase RhoGAP PF00620.22 KNZ81801.1 - 2.7e-35 121.2 0.0 4.5e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 KNZ81801.1 - 0.0049 15.7 0.0 0.0077 15.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Glyco_hydro_17 PF00332.13 KNZ81802.1 - 1.5e-10 40.6 6.9 1.7e-08 33.8 0.9 2.5 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Drf_GBD PF06371.8 KNZ81803.1 - 2.1e-15 56.5 0.2 1.6e-11 43.9 0.0 2.4 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain GMC_oxred_N PF00732.14 KNZ81804.1 - 1.6e-61 208.1 0.0 2e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KNZ81804.1 - 2.6e-27 95.8 0.0 7e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KNZ81804.1 - 3.2e-05 23.8 0.2 9.3e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KNZ81804.1 - 4.1e-05 22.6 0.0 0.00012 21.0 0.0 1.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KNZ81804.1 - 0.00015 20.7 0.1 0.0026 16.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KNZ81804.1 - 0.00021 20.3 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KNZ81804.1 - 0.0028 17.5 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KNZ81804.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KNZ81804.1 - 0.033 12.6 0.0 0.053 11.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KNZ81804.1 - 0.072 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family RVP_2 PF08284.6 KNZ81805.1 - 0.0013 18.6 0.1 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KNZ81805.1 - 0.049 14.1 0.0 0.075 13.5 0.0 1.4 1 1 0 1 1 1 0 Aspartyl protease DnaJ PF00226.26 KNZ81808.1 - 1.3e-16 60.0 0.0 2.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KNZ81808.1 - 7.7e-05 22.5 0.0 0.032 14.1 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain BH4 PF02180.12 KNZ81808.1 - 0.54 9.7 2.4 1 8.9 1.6 1.4 1 0 0 1 1 1 0 Bcl-2 homology region 4 Kelch_5 PF13854.1 KNZ81809.1 - 4.5e-13 48.8 0.2 3.5e-05 23.6 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 KNZ81809.1 - 2.4e-10 39.7 0.0 0.00072 19.2 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 KNZ81809.1 - 2.2e-08 33.7 1.0 0.015 15.0 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 KNZ81809.1 - 1.3e-07 31.5 1.5 0.027 14.6 0.1 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KNZ81809.1 - 0.00033 20.7 3.2 0.13 12.4 0.2 3.7 2 1 1 3 3 3 1 Kelch motif Rax2 PF12768.2 KNZ81809.1 - 0.022 13.9 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Kelch_1 PF01344.20 KNZ81809.1 - 0.1 12.1 0.0 24 4.5 0.0 2.8 2 0 0 2 2 2 0 Kelch motif DUF1616 PF07760.6 KNZ81809.1 - 0.23 10.5 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) ACBP PF00887.14 KNZ81810.1 - 6.4e-29 99.4 0.7 9.9e-29 98.8 0.5 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein DSX_dimer PF08828.5 KNZ81810.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Doublesex dimerisation domain PH PF00169.24 KNZ81811.1 - 8.5e-32 109.4 2.1 3.1e-18 65.8 0.2 2.6 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 KNZ81811.1 - 4e-18 65.6 3.2 1.9e-08 34.5 1.7 3.4 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 KNZ81811.1 - 4.1e-11 42.6 0.1 3.2e-06 26.9 0.0 3.4 3 0 0 3 3 3 2 PH domain PH_8 PF15409.1 KNZ81811.1 - 1.3e-07 31.5 1.1 1.3e-05 25.2 0.1 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.1 KNZ81811.1 - 0.0003 20.9 1.2 0.26 11.4 0.6 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.1 KNZ81811.1 - 0.0064 16.0 0.8 0.13 11.8 0.0 3.0 4 0 0 4 4 4 1 Pleckstrin homology domain Mcp5_PH PF12814.2 KNZ81811.1 - 0.23 11.4 5.8 1.4 8.8 0.0 3.1 3 1 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology Fungal_trans_2 PF11951.3 KNZ81812.1 - 7.1e-28 97.2 6.2 9.4e-28 96.8 4.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ81812.1 - 0.00028 20.7 6.9 0.00055 19.7 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KNZ81813.1 - 5.4e-37 127.2 0.8 7.2e-37 126.8 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ81813.1 - 9.3e-05 22.2 8.3 0.00017 21.4 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VTC PF09359.5 KNZ81814.1 - 7.1e-97 323.8 0.9 1.2e-96 323.1 0.0 1.8 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 KNZ81814.1 - 6.2e-16 58.9 17.9 1.6e-15 57.6 5.4 3.1 2 2 0 2 2 2 1 SPX domain DUF202 PF02656.10 KNZ81814.1 - 1.5e-09 37.8 1.9 3.2e-09 36.8 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Gtr1_RagA PF04670.7 KNZ81815.1 - 3.4e-56 189.9 0.1 4.3e-56 189.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 KNZ81815.1 - 0.00038 19.7 0.0 0.00053 19.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KNZ81815.1 - 0.0021 18.5 0.0 0.0048 17.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_14 PF13173.1 KNZ81815.1 - 0.015 15.2 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KNZ81815.1 - 0.033 13.8 0.2 0.56 9.8 0.2 2.3 1 1 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 KNZ81815.1 - 0.041 13.8 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ras PF00071.17 KNZ81815.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Ras family SRPRB PF09439.5 KNZ81815.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Acyl_transf_1 PF00698.16 KNZ81816.1 - 1.6e-64 218.2 0.0 2.9e-62 210.8 0.0 3.0 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 KNZ81816.1 - 4.6e-28 97.0 0.1 1.9e-27 95.0 0.0 2.0 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 KNZ81816.1 - 7.1e-28 96.1 2.5 1.5e-27 95.1 0.7 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) ketoacyl-synt PF00109.21 KNZ81816.1 - 1.1e-24 87.2 0.3 2.7e-24 86.0 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 KNZ81816.1 - 1.6e-14 54.2 0.0 7.2e-13 48.8 0.0 3.2 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 KNZ81816.1 - 5.4e-14 52.0 0.0 1.4e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 KNZ81816.1 - 1.6e-13 50.4 0.0 4e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.20 KNZ81816.1 - 8e-08 32.3 0.0 0.00018 21.4 0.0 2.8 2 0 0 2 2 2 2 short chain dehydrogenase Thiolase_N PF00108.18 KNZ81816.1 - 0.031 13.2 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain DEAD PF00270.24 KNZ81817.1 - 2.1e-36 124.9 0.4 1.9e-35 121.8 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KNZ81817.1 - 2.9e-20 71.9 0.0 6.5e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 KNZ81817.1 - 0.0071 16.3 0.0 0.024 14.5 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain AAA_22 PF13401.1 KNZ81817.1 - 0.021 14.9 0.6 0.32 11.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain CTP_transf_2 PF01467.21 KNZ81818.1 - 0.15 12.1 0.0 4.8 7.2 0.0 2.4 2 1 0 2 2 2 0 Cytidylyltransferase WD40 PF00400.27 KNZ81819.1 - 3.7e-24 83.6 5.8 3.8e-06 26.5 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KNZ81819.1 - 0.12 10.4 0.3 0.42 8.6 0.1 1.9 2 1 0 2 2 2 0 Nucleoporin Nup120/160 p450 PF00067.17 KNZ81820.1 - 1.1e-67 228.6 0.0 1.2e-67 228.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNB PF00773.14 KNZ81821.1 - 3.6e-49 167.8 0.0 6.7e-49 166.9 0.0 1.5 1 0 0 1 1 1 1 RNB domain Filo_glycop PF01611.11 KNZ81822.1 - 2.4 6.8 7.6 3.3 6.3 5.3 1.2 1 0 0 1 1 1 0 Filovirus glycoprotein Pkinase PF00069.20 KNZ81823.1 - 1.4e-45 155.5 0.0 7.3e-26 90.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81823.1 - 9.9e-19 67.4 0.0 1.9e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KNZ81823.1 - 5.1e-05 22.3 0.0 0.0046 15.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KNZ81823.1 - 0.0064 16.2 0.3 0.019 14.6 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Vps51 PF08700.6 KNZ81824.1 - 2.5e-24 84.9 3.5 3.5e-24 84.4 2.4 1.2 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 KNZ81824.1 - 0.00058 18.4 2.9 0.00074 18.0 2.0 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 KNZ81824.1 - 0.0013 18.7 5.0 0.0017 18.3 3.4 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 FlgN PF05130.7 KNZ81824.1 - 0.0016 18.6 1.4 0.0022 18.2 1.0 1.2 1 0 0 1 1 1 1 FlgN protein DUF3086 PF11285.3 KNZ81824.1 - 0.084 11.6 0.7 0.12 11.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) PROL5-SMR PF15621.1 KNZ81824.1 - 0.14 12.6 5.0 0.2 12.1 3.4 1.3 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Yip1 PF04893.12 KNZ81826.1 - 2.1e-14 53.4 16.6 3.1e-14 52.8 11.5 1.3 1 0 0 1 1 1 1 Yip1 domain DUF4199 PF13858.1 KNZ81826.1 - 0.0079 16.1 1.6 0.0079 16.1 1.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) DUF1282 PF06930.7 KNZ81826.1 - 1.7 8.2 10.2 2.6 7.6 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) AAA PF00004.24 KNZ81827.1 - 8.7e-42 142.4 0.0 1.5e-41 141.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KNZ81827.1 - 1.8e-06 28.0 0.1 0.00035 20.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KNZ81827.1 - 4.6e-06 26.6 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KNZ81827.1 - 5.3e-05 22.2 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KNZ81827.1 - 0.00019 21.1 0.3 0.00099 18.8 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KNZ81827.1 - 0.00026 21.0 0.1 0.0019 18.2 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KNZ81827.1 - 0.0006 18.9 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KNZ81827.1 - 0.0041 17.0 0.0 0.009 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KNZ81827.1 - 0.0055 16.3 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KNZ81827.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ81827.1 - 0.007 17.1 0.8 0.017 15.9 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KNZ81827.1 - 0.0071 16.0 0.3 0.015 15.0 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 KNZ81827.1 - 0.0093 15.1 0.2 0.3 10.1 0.1 2.2 1 1 0 2 2 2 1 KaiC IstB_IS21 PF01695.12 KNZ81827.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 KNZ81827.1 - 0.013 15.8 0.3 0.034 14.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KNZ81827.1 - 0.013 15.4 0.4 0.05 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KNZ81827.1 - 0.026 14.1 0.4 0.42 10.2 0.1 2.5 2 1 1 3 3 2 0 NACHT domain NB-ARC PF00931.17 KNZ81827.1 - 0.028 13.2 0.1 0.067 12.0 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 KNZ81827.1 - 0.033 13.5 1.0 1.7 8.0 0.2 2.6 2 1 1 3 3 2 0 AAA domain Zeta_toxin PF06414.7 KNZ81827.1 - 0.044 12.8 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 KNZ81827.1 - 0.07 11.8 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus DUF2075 PF09848.4 KNZ81827.1 - 0.073 12.0 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KNZ81827.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SKI PF01202.17 KNZ81827.1 - 0.077 12.8 0.4 4 7.2 0.0 2.5 3 0 0 3 3 2 0 Shikimate kinase RNA_helicase PF00910.17 KNZ81827.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 KNZ81827.1 - 0.12 11.6 0.2 0.39 9.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 KNZ81827.1 - 0.12 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KNZ81827.1 - 0.15 11.6 0.2 0.39 10.2 0.2 1.6 1 0 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.14 KNZ81828.1 - 3.7e-12 45.9 0.1 5.5e-10 38.8 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 KNZ81828.1 - 0.011 14.5 0.0 0.025 13.3 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase KcnmB2_inactiv PF09303.5 KNZ81828.1 - 0.044 13.5 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 KCNMB2, ball and chain domain SAA PF00277.13 KNZ81828.1 - 0.095 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Serum amyloid A protein FAD_binding_3 PF01494.14 KNZ81829.1 - 2.9e-15 56.1 0.0 1.2e-09 37.7 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 KNZ81829.1 - 0.018 13.9 0.1 0.079 11.7 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.1 KNZ81829.1 - 0.022 14.7 0.0 0.082 12.9 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KNZ81830.1 - 6.3e-11 41.9 0.4 1.8e-07 30.5 0.1 2.1 1 1 1 2 2 2 2 FAD binding domain SE PF08491.5 KNZ81830.1 - 0.035 12.9 0.1 0.17 10.6 0.0 2.0 2 1 0 2 2 2 0 Squalene epoxidase Med26 PF08711.6 KNZ81834.1 - 2.3e-11 42.9 0.0 9.1e-11 41.0 0.0 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Imm2 PF14426.1 KNZ81834.1 - 0.023 14.6 2.6 2.9 7.9 0.1 2.5 2 0 0 2 2 2 0 Immunity protein Imm2 TPR_11 PF13414.1 KNZ81837.1 - 5.3e-08 32.3 4.7 5.4e-07 29.1 1.1 2.9 1 1 0 2 2 2 1 TPR repeat TPR_19 PF14559.1 KNZ81837.1 - 4.2e-05 23.7 1.2 4.2e-05 23.7 0.8 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ81837.1 - 0.00044 19.9 2.5 2.5 8.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ81837.1 - 0.00093 19.6 0.1 0.3 11.8 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KNZ81837.1 - 0.0036 17.4 2.4 0.011 15.8 0.2 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KNZ81837.1 - 0.007 17.0 0.8 9.3 7.0 0.0 2.9 2 1 0 3 3 3 0 Tetratricopeptide repeat DUF2654 PF10849.3 KNZ81837.1 - 0.016 14.9 0.5 0.039 13.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) PPR_3 PF13812.1 KNZ81837.1 - 0.036 14.3 0.0 12 6.5 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TPR_20 PF14561.1 KNZ81837.1 - 0.052 13.6 2.9 0.52 10.4 0.5 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 KNZ81837.1 - 0.064 13.2 0.4 3.2 7.9 0.0 3.0 3 0 0 3 3 3 0 PPR repeat SgrR_N PF12793.2 KNZ81837.1 - 0.1 12.6 0.8 0.81 9.7 0.0 2.3 2 0 0 2 2 2 0 Sugar transport-related sRNA regulator N-term TPR_7 PF13176.1 KNZ81837.1 - 0.1 12.4 0.7 23 5.1 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat LUC7 PF03194.10 KNZ81837.1 - 0.12 11.8 3.6 0.18 11.2 2.5 1.4 1 0 0 1 1 1 0 LUC7 N_terminus DUF1018 PF06252.7 KNZ81837.1 - 0.16 12.5 2.1 0.58 10.6 0.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1018) TPR_17 PF13431.1 KNZ81837.1 - 0.39 11.0 3.7 1.4 9.3 0.2 3.0 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ81837.1 - 2.3 7.9 4.6 15 5.3 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat NMT1 PF09084.6 KNZ81838.1 - 0.0002 21.0 0.0 0.00057 19.5 0.0 1.7 1 1 1 2 2 2 1 NMT1/THI5 like Phosphonate-bd PF12974.2 KNZ81838.1 - 0.00063 19.1 0.0 0.00083 18.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 KNZ81838.1 - 0.0024 17.1 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.1 KNZ81838.1 - 0.0027 17.1 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family GSHPx PF00255.14 KNZ81839.1 - 1.6e-40 136.8 0.1 2.1e-40 136.4 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KNZ81839.1 - 0.00011 21.9 0.0 0.00017 21.2 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KNZ81839.1 - 0.00038 20.0 0.2 0.0013 18.2 0.0 1.9 1 1 1 2 2 2 1 Redoxin Mito_carr PF00153.22 KNZ81840.1 - 1.4e-08 34.3 0.0 4.9e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial carrier protein CAF-1_p150 PF11600.3 KNZ81841.1 - 8.4 5.7 17.7 4.7 6.5 10.4 1.7 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Metallophos PF00149.23 KNZ81842.1 - 3.5e-09 36.3 4.3 1.8e-08 33.9 3.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KNZ81842.1 - 0.0026 17.6 0.0 0.0035 17.1 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.6 KNZ81842.1 - 0.045 11.7 0.1 0.11 10.4 0.0 1.6 2 0 0 2 2 2 0 Firmicute fructose-1,6-bisphosphatase UBN2_2 PF14227.1 KNZ81843.1 - 1.4e-10 40.7 0.1 2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ81843.1 - 1.6e-07 31.0 0.0 2.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type LolB PF03550.9 KNZ81844.1 - 0.086 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB PAPA-1 PF04795.7 KNZ81844.1 - 0.32 11.7 3.3 0.77 10.4 0.4 2.2 1 1 1 2 2 2 0 PAPA-1-like conserved region Metallophos PF00149.23 KNZ81845.1 - 1.7e-42 145.1 1.1 2.1e-42 144.7 0.8 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cpn60_TCP1 PF00118.19 KNZ81846.1 - 2.5e-140 468.3 0.2 2.9e-140 468.1 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family COesterase PF00135.23 KNZ81847.1 - 2.7e-96 323.4 0.0 2.9e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ81847.1 - 3e-07 30.2 0.1 3.9e-06 26.5 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold UBA_4 PF14555.1 KNZ81847.1 - 0.013 14.9 1.7 0.075 12.5 0.2 2.3 2 0 0 2 2 2 0 UBA-like domain Abhydrolase_5 PF12695.2 KNZ81847.1 - 0.091 12.5 0.1 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ81847.1 - 0.12 11.5 0.1 0.23 10.6 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family PfkB PF00294.19 KNZ81848.1 - 1.3e-11 44.2 0.0 0.00037 19.7 0.0 3.1 3 0 0 3 3 3 3 pfkB family carbohydrate kinase TPR_16 PF13432.1 KNZ81849.1 - 1.2e-17 64.0 1.2 1.4e-08 35.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ81849.1 - 4.1e-16 59.0 3.9 1e-06 28.9 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ81849.1 - 9.7e-14 50.7 0.8 5.1e-05 22.8 0.0 3.8 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 KNZ81849.1 - 1.8e-13 49.2 0.3 0.11 12.4 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ81849.1 - 1.1e-11 44.2 10.1 0.0057 17.1 0.0 6.4 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ81849.1 - 6.7e-11 41.3 0.1 0.18 11.4 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ81849.1 - 3.7e-09 36.0 0.0 0.0011 18.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ81849.1 - 2.3e-08 33.8 0.4 0.12 12.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KNZ81849.1 - 7.5e-07 29.1 0.0 0.0021 18.1 0.0 3.5 3 1 1 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 KNZ81849.1 - 1e-05 25.2 0.5 0.0052 16.6 0.0 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KNZ81849.1 - 0.00014 22.1 1.9 42 4.9 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 KNZ81849.1 - 0.00026 21.0 1.7 0.6 10.2 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KNZ81849.1 - 0.00071 19.3 6.3 0.39 10.6 0.3 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ81849.1 - 0.0037 16.9 1.7 1.7 8.6 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 KNZ81849.1 - 0.0068 16.7 2.0 1.6 9.4 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KNZ81849.1 - 0.014 15.1 0.0 31 4.6 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KNZ81849.1 - 0.028 14.6 0.1 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation DUF1703 PF08011.6 KNZ81851.1 - 0.0039 16.9 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1703) Peptidase_M48 PF01435.13 KNZ81852.1 - 6e-18 65.2 0.0 9.1e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_MA_2 PF13485.1 KNZ81852.1 - 0.062 13.3 0.1 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily COX5B PF01215.14 KNZ81854.1 - 1.3e-38 131.7 0.0 1.7e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Na_Ca_ex PF01699.19 KNZ81855.1 - 1.2e-22 80.0 23.8 8.8e-19 67.5 7.3 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Lipase_GDSL_2 PF13472.1 KNZ81856.1 - 8.1e-20 71.6 2.7 9.8e-20 71.4 1.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KNZ81856.1 - 2.4e-11 43.8 0.1 3.3e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Peptidase_M15_3 PF08291.6 KNZ81856.1 - 0.026 14.3 0.0 0.072 12.8 0.0 1.7 1 1 0 1 1 1 0 Peptidase M15 TetR_N PF00440.18 KNZ81856.1 - 0.14 11.8 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family PRK PF00485.13 KNZ81857.1 - 2.7e-47 160.8 0.0 4e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 KNZ81857.1 - 8.6e-45 152.4 0.0 1e-42 145.7 0.0 2.2 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 KNZ81857.1 - 2.2e-07 31.6 0.0 5.6e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KNZ81857.1 - 2.2e-06 28.0 0.0 4.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KNZ81857.1 - 0.00024 20.2 0.0 0.00043 19.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KNZ81857.1 - 0.00042 20.2 0.0 0.00086 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KNZ81857.1 - 0.0024 17.5 0.0 0.02 14.6 0.0 2.4 3 0 0 3 3 3 1 Part of AAA domain UPF0079 PF02367.12 KNZ81857.1 - 0.0075 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 KNZ81857.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KNZ81857.1 - 0.028 14.4 0.1 0.099 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 KNZ81857.1 - 0.081 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 KNZ81857.1 - 0.12 12.6 0.0 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KNZ81857.1 - 0.27 10.1 0.0 0.38 9.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF2392 PF10288.4 KNZ81858.1 - 1.6e-09 38.0 0.0 6.1e-09 36.1 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) zf-C3HC4_3 PF13920.1 KNZ81858.1 - 0.025 14.2 1.4 0.025 14.2 1.0 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) ATP_bind_3 PF01171.15 KNZ81858.1 - 0.11 12.0 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 PP-loop family zf-P11 PF03854.9 KNZ81858.1 - 0.12 11.8 1.1 5 6.6 0.0 2.5 2 0 0 2 2 2 0 P-11 zinc finger zf-C3HC4_2 PF13923.1 KNZ81858.1 - 0.39 10.7 4.8 0.62 10.1 1.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Gin PF10764.4 KNZ81858.1 - 0.68 9.6 5.6 12 5.6 1.3 3.2 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin DUF2183 PF09949.4 KNZ81859.1 - 5.3e-20 71.2 0.0 9.4e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) AIG2 PF06094.7 KNZ81860.1 - 1.3e-13 51.2 0.0 1.6e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family FRG PF08867.6 KNZ81861.1 - 0.058 13.9 2.2 0.34 11.4 1.5 2.2 1 1 0 1 1 1 0 FRG domain DUF310 PF03750.8 KNZ81861.1 - 0.59 10.3 4.2 1 9.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF310) HalX PF08663.5 KNZ81861.1 - 0.75 9.8 11.6 2.2 8.3 3.6 3.4 3 1 1 4 4 4 0 HalX domain NPV_P10 PF05531.7 KNZ81861.1 - 0.88 9.8 6.3 31 4.9 1.0 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4559 PF15112.1 KNZ81861.1 - 1.9 7.6 9.0 0.71 8.9 1.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Seryl_tRNA_N PF02403.17 KNZ81861.1 - 2.3 8.2 12.1 0.27 11.2 1.1 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 KNZ81861.1 - 5 7.5 7.1 31 4.9 0.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 KNZ81861.1 - 7.4 7.0 11.6 5.4 7.5 0.2 2.9 2 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 KNZ81861.1 - 7.7 5.4 12.7 35 3.2 7.8 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF1003 PF06210.6 KNZ81861.1 - 8.8 6.3 6.3 8 6.4 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1003) Metallophos PF00149.23 KNZ81862.1 - 5.9e-11 42.1 0.1 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KNZ81862.1 - 5.3e-07 29.5 0.0 1.1e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_C14 PF00656.17 KNZ81863.1 - 4.9e-69 232.7 0.2 6e-69 232.4 0.1 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KNZ81863.1 - 0.069 12.9 0.7 0.6 9.9 0.0 2.5 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain TAF1D PF15333.1 KNZ81864.1 - 0.0015 18.3 1.1 0.004 16.9 0.8 1.7 1 0 0 1 1 1 1 TATA box-binding protein-associated factor 1D HSP20 PF00011.16 KNZ81865.1 - 2.1e-07 30.7 0.0 3.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family UvrD_C PF13361.1 KNZ81866.1 - 2.8e-81 273.6 0.0 4.5e-81 273.0 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KNZ81866.1 - 1.6e-62 211.6 0.0 2.8e-62 210.8 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KNZ81866.1 - 3.4e-14 52.8 0.0 1.5e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KNZ81866.1 - 3.5e-14 52.3 0.0 1.5e-12 47.0 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 KNZ81866.1 - 6.9e-10 38.8 0.2 0.0065 16.0 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 KNZ81866.1 - 0.033 13.5 0.0 0.31 10.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain tRNA-synt_1g PF09334.6 KNZ81867.1 - 1.7e-127 425.3 0.0 2.1e-127 425.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.15 KNZ81867.1 - 9.9e-07 28.3 1.1 9.9e-07 28.3 0.8 2.1 2 0 0 2 2 2 1 WHEP-TRS domain tRNA-synt_1 PF00133.17 KNZ81867.1 - 2.1e-05 22.7 0.0 0.00028 19.0 0.0 2.7 2 2 1 3 3 3 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KNZ81867.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DZR PF12773.2 KNZ81867.1 - 1.5 8.7 7.1 4.7 7.1 4.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon OPT PF03169.10 KNZ81868.1 - 3.1e-138 461.9 23.4 3.6e-138 461.7 16.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Zip PF02535.17 KNZ81868.1 - 0.00096 18.2 2.8 1.1 8.1 0.0 3.9 3 1 0 4 4 4 3 ZIP Zinc transporter DUF1183 PF06682.7 KNZ81869.1 - 1.5e-55 189.0 0.4 3.7e-54 184.5 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) Cellulase PF00150.13 KNZ81870.1 - 3.4e-43 147.8 0.6 5.1e-43 147.2 0.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KNZ81870.1 - 2.4e-08 33.5 6.9 2.4e-08 33.5 4.8 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain MSP1_C PF07462.6 KNZ81870.1 - 0.078 11.3 1.3 0.14 10.4 0.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Cellulase PF00150.13 KNZ81871.1 - 1.6e-42 145.6 0.4 2.4e-42 145.0 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KNZ81871.1 - 7.4e-08 31.9 5.0 7.4e-08 31.9 3.5 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain MSP1_C PF07462.6 KNZ81871.1 - 0.45 8.8 1.1 0.81 8.0 0.8 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Sporozoite_P67 PF05642.6 KNZ81871.1 - 2.6 5.8 6.6 3.7 5.2 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MFS_1 PF07690.11 KNZ81872.1 - 3.2e-23 82.0 13.3 4.3e-20 71.7 4.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KNZ81874.1 - 4.5e-13 48.6 14.9 4.5e-13 48.6 10.3 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Bud13 PF09736.4 KNZ81875.1 - 3.7e-44 150.5 7.2 3.7e-44 150.5 5.0 3.1 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Sad1_UNC PF07738.8 KNZ81875.1 - 2.9e-21 75.6 0.0 9.3e-10 38.4 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Abhydrolase_1 PF00561.15 KNZ81876.1 - 1.2e-30 106.8 0.0 4.4e-30 104.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KNZ81876.1 - 1.5e-27 96.9 0.1 2.2e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ81876.1 - 1.3e-13 50.9 0.0 1.2e-12 47.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KNZ81876.1 - 0.00017 20.8 0.0 0.38 9.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KNZ81876.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.6 1 1 0 1 1 1 0 Putative lysophospholipase Ndr PF03096.9 KNZ81876.1 - 0.016 13.6 0.0 0.023 13.1 0.0 1.1 1 0 0 1 1 1 0 Ndr family Isochorismatase PF00857.15 KNZ81876.1 - 0.04 13.8 0.0 8.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Isochorismatase family Abhydrolase_4 PF08386.5 KNZ81876.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein CRAL_TRIO PF00650.15 KNZ81877.1 - 1.9e-27 95.6 0.0 2.9e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KNZ81877.1 - 2.1e-06 27.7 0.1 4.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KNZ81877.1 - 0.037 13.9 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain RhoGEF PF00621.15 KNZ81878.1 - 1e-32 113.4 0.5 1.6e-32 112.8 0.3 1.3 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.17 KNZ81878.1 - 9.2e-24 84.3 0.0 1.2e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 CNH domain Cu-oxidase PF00394.17 KNZ81880.1 - 8.9e-39 132.9 0.5 3.4e-37 127.8 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KNZ81880.1 - 1.1e-35 121.8 1.6 5.5e-29 100.2 0.1 3.4 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.9 KNZ81880.1 - 9.9e-35 119.0 1.3 1.2e-33 115.4 0.4 2.6 2 1 0 2 2 2 1 Multicopper oxidase WD40 PF00400.27 KNZ81881.1 - 2.9e-47 156.9 11.1 1.8e-11 43.4 0.1 8.9 8 1 0 8 8 8 6 WD domain, G-beta repeat DUF155 PF02582.9 KNZ81881.1 - 9e-41 139.6 0.0 1.3e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 PQQ_2 PF13360.1 KNZ81881.1 - 0.01 15.2 2.2 0.067 12.6 0.5 2.8 2 1 1 3 3 3 0 PQQ-like domain Nup160 PF11715.3 KNZ81881.1 - 0.033 12.3 0.0 0.3 9.1 0.0 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 DUF4613 PF15390.1 KNZ81881.1 - 0.039 12.1 0.0 0.062 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Fusion_gly PF00523.13 KNZ81881.1 - 0.33 8.9 0.2 0.51 8.3 0.1 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Thioredoxin PF00085.15 KNZ81882.1 - 2.8e-58 194.0 0.5 1.2e-29 102.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 KNZ81882.1 - 1.6e-20 73.5 1.4 2.1e-20 73.1 0.1 1.9 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 KNZ81882.1 - 1.5e-19 70.2 0.4 7.4e-09 35.7 0.1 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KNZ81882.1 - 1.8e-15 56.7 0.3 1.3e-05 25.1 0.0 4.3 2 2 2 4 4 4 4 Thioredoxin-like Thioredoxin_7 PF13899.1 KNZ81882.1 - 4.1e-15 55.5 0.0 2.8e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 KNZ81882.1 - 4.5e-10 39.2 0.2 0.0015 18.2 0.0 2.8 2 1 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.1 KNZ81882.1 - 5.8e-09 36.0 1.2 1.6e-06 28.0 1.3 3.2 1 1 1 2 2 2 1 Thioredoxin-like domain ERp29_N PF07912.8 KNZ81882.1 - 6.7e-09 35.7 0.2 0.00014 21.8 0.0 2.4 2 0 0 2 2 2 2 ERp29, N-terminal domain Redoxin PF08534.5 KNZ81882.1 - 1.1e-06 28.2 0.7 0.025 14.1 0.1 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 KNZ81882.1 - 0.00012 21.6 0.2 0.22 11.0 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.1 KNZ81882.1 - 0.0007 19.3 0.0 0.44 10.4 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.1 KNZ81882.1 - 0.00079 19.4 2.3 1.7 8.6 0.0 3.3 2 2 0 2 2 2 2 Thioredoxin TraF PF13728.1 KNZ81882.1 - 0.001 18.6 0.0 0.47 9.9 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_5 PF13743.1 KNZ81882.1 - 0.0093 15.5 0.2 10 5.6 0.0 3.4 2 2 2 4 4 4 0 Thioredoxin DUF836 PF05768.9 KNZ81882.1 - 0.021 15.0 0.0 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) GTSE1_N PF15259.1 KNZ81882.1 - 0.029 14.3 0.1 0.066 13.1 0.1 1.6 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 Glutaredoxin PF00462.19 KNZ81882.1 - 0.034 14.1 5.5 0.18 11.7 0.1 3.5 3 2 0 3 3 3 0 Glutaredoxin HyaE PF07449.6 KNZ81882.1 - 0.038 13.9 0.0 9.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Exo_endo_phos PF03372.18 KNZ81883.1 - 1.3e-07 31.8 0.1 1.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sugar_tr PF00083.19 KNZ81885.1 - 3e-71 240.3 22.4 3.7e-71 240.0 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ81885.1 - 3.1e-22 78.7 32.9 1.2e-19 70.3 15.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-amylase PF00128.19 KNZ81886.1 - 1.3e-18 67.5 3.2 2.2e-17 63.4 0.0 3.5 2 1 1 3 3 3 1 Alpha amylase, catalytic domain TPR_MLP1_2 PF07926.7 KNZ81886.1 - 0.00076 19.2 32.1 0.052 13.2 5.8 3.4 1 1 2 3 3 3 3 TPR/MLP1/MLP2-like protein Glyco_hydro_70 PF02324.11 KNZ81886.1 - 0.0029 15.4 0.0 0.35 8.5 0.0 3.0 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 Fmp27 PF10344.4 KNZ81886.1 - 0.99 7.0 6.2 1.8 6.1 4.3 1.4 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Sugar_tr PF00083.19 KNZ81887.1 - 2.5e-111 372.4 28.1 3.3e-111 372.0 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ81887.1 - 6.2e-23 81.0 52.4 1e-16 60.6 12.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KNZ81887.1 - 0.084 11.2 38.5 0.27 9.6 7.3 3.9 2 2 0 3 3 3 0 MFS/sugar transport protein Mito_carr PF00153.22 KNZ81890.1 - 0.039 13.6 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial carrier protein Brix PF04427.13 KNZ81891.1 - 1.1e-29 103.4 0.0 1.5e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain ADH_zinc_N PF00107.21 KNZ81892.1 - 4.5e-17 61.8 0.0 9e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KNZ81892.1 - 0.00079 20.3 0.0 0.0016 19.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PhoH PF02562.11 KNZ81892.1 - 0.0058 15.8 0.0 0.013 14.7 0.0 1.5 2 0 0 2 2 2 1 PhoH-like protein ADH_N PF08240.7 KNZ81892.1 - 0.057 13.1 0.6 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain MIP PF00230.15 KNZ81894.1 - 1.8e-22 79.9 5.9 2.3e-22 79.5 4.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein YbgT_YccB PF08173.6 KNZ81894.1 - 9.8 6.0 8.6 10 6.0 0.0 3.1 3 0 0 3 3 3 0 Membrane bound YbgT-like protein SART-1 PF03343.8 KNZ81895.1 - 4e-128 428.4 55.8 5e-128 428.1 35.9 1.9 2 0 0 2 2 2 2 SART-1 family LsmAD PF06741.8 KNZ81896.1 - 5.9e-26 90.3 0.4 1.1e-25 89.5 0.3 1.5 1 0 0 1 1 1 1 LsmAD domain Cut8_N PF14482.1 KNZ81898.1 - 0.32 11.0 2.1 0.89 9.6 1.4 1.9 1 1 0 1 1 1 0 Cut8 proteasome-binding domain Pkinase PF00069.20 KNZ81900.1 - 1.1e-17 64.0 0.0 3.7e-17 62.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81900.1 - 1.1e-06 27.8 0.0 0.00013 21.1 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KNZ81900.1 - 0.011 14.7 0.0 0.049 12.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ81900.1 - 0.018 14.8 0.6 0.037 13.7 0.2 1.6 1 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KNZ81900.1 - 0.15 11.3 0.0 0.35 10.1 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 KNZ81901.1 - 2e-16 59.9 0.0 3.9e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Mad3_BUB1_I PF08311.7 KNZ81901.1 - 1.9e-14 53.5 0.1 3.4e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase_Tyr PF07714.12 KNZ81901.1 - 1.1e-07 31.2 0.0 1.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 KNZ81901.1 - 0.013 15.3 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 Terpene_synth_C PF03936.11 KNZ81902.1 - 4.6e-21 75.2 0.2 6e-21 74.8 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.11 KNZ81903.1 - 0.00071 18.8 0.1 0.001 18.3 0.1 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 KNZ81905.1 - 3.4e-43 147.8 0.0 5.8e-43 147.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF1229 PF06797.6 KNZ81906.1 - 0.002 17.0 0.2 0.0023 16.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1229) 7tm_3 PF00003.17 KNZ81906.1 - 0.0066 15.8 1.4 0.0085 15.4 1.0 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Cation_efflux PF01545.16 KNZ81906.1 - 0.029 13.4 2.9 0.038 13.0 2.0 1.2 1 0 0 1 1 1 0 Cation efflux family CoatB PF10389.4 KNZ81906.1 - 0.4 10.5 0.1 0.4 10.5 0.1 2.8 3 0 0 3 3 3 0 Bacteriophage coat protein B CRPA PF05745.6 KNZ81906.1 - 1.3 8.8 6.1 0.55 10.0 2.7 1.5 1 1 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) YrvL PF14184.1 KNZ81906.1 - 2.1 8.1 7.7 1.7 8.4 3.3 1.9 2 0 0 2 2 2 0 Regulatory protein YrvL Xpo1 PF08389.7 KNZ81909.1 - 1.2e-16 60.9 5.6 3e-16 59.6 0.0 4.2 5 1 1 6 6 6 1 Exportin 1-like protein HEAT_2 PF13646.1 KNZ81909.1 - 0.014 15.7 0.0 17 5.7 0.0 3.7 2 0 0 2 2 2 0 HEAT repeats RPAP3_C PF13877.1 KNZ81909.1 - 0.025 14.5 1.1 0.54 10.2 0.1 3.1 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 HEAT PF02985.17 KNZ81909.1 - 0.14 12.3 8.5 1.3 9.2 0.1 4.7 4 1 1 5 5 5 0 HEAT repeat Cullin PF00888.17 KNZ81910.1 - 2.5e-146 488.6 0.0 3.1e-146 488.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KNZ81910.1 - 1.4e-28 98.4 0.9 3.6e-28 97.1 0.6 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain DnaJ PF00226.26 KNZ81911.1 - 4.1e-24 84.0 4.1 6.7e-24 83.4 2.8 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KNZ81911.1 - 2.2e-20 72.2 0.0 1.6e-17 63.1 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KNZ81911.1 - 2.5e-16 59.4 16.0 4.8e-16 58.5 11.1 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KNZ81911.1 - 8.5e-06 25.4 2.5 0.062 12.9 0.9 2.2 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 KNZ81911.1 - 0.00078 19.7 6.8 0.25 11.6 0.1 3.2 1 1 1 2 2 2 2 Restriction alleviation protein Lar PAAR_motif PF05488.8 KNZ81911.1 - 0.12 12.3 8.1 1.9 8.5 0.3 2.8 1 1 1 2 2 2 0 PAAR motif DZR PF12773.2 KNZ81911.1 - 0.55 10.0 11.0 12 5.7 7.7 2.2 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_6 PF14599.1 KNZ81911.1 - 1.5 8.7 6.0 1.2 9.0 0.3 2.5 2 0 0 2 2 2 0 Zinc-ribbon A2L_zn_ribbon PF08792.5 KNZ81911.1 - 3.7 7.1 11.1 21 4.7 0.2 3.5 2 1 1 3 3 3 0 A2L zinc ribbon domain zf-RING_5 PF14634.1 KNZ81911.1 - 8 6.2 8.9 4.4 7.0 1.2 2.3 2 0 0 2 2 2 0 zinc-RING finger domain WLM PF08325.5 KNZ81913.1 - 5.1e-42 143.8 0.0 9.6e-42 142.9 0.0 1.5 1 1 0 1 1 1 1 WLM domain TRF PF08558.5 KNZ81913.1 - 0.11 11.8 0.7 0.19 11.0 0.5 1.3 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) DUF3421 PF11901.3 KNZ81914.1 - 4.4e-11 42.5 0.6 9.7e-11 41.4 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3421) Dimer_Tnp_hAT PF05699.9 KNZ81915.1 - 4.6e-07 29.3 0.0 6.1e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TPR_1 PF00515.23 KNZ81915.1 - 0.075 12.6 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Sugar_tr PF00083.19 KNZ81916.1 - 5.8e-33 114.1 27.5 1.3e-18 66.8 5.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KNZ81916.1 - 6.2e-15 54.7 44.1 1e-08 34.3 11.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 KNZ81916.1 - 0.0087 15.5 6.2 0.0087 15.5 4.3 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 M11L PF11099.3 KNZ81916.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Apoptosis regulator M11L like DSS1_SEM1 PF05160.8 KNZ81917.1 - 7.4e-20 70.4 13.1 1.6e-19 69.4 8.8 1.7 1 1 0 1 1 1 1 DSS1/SEM1 family SIR2 PF02146.12 KNZ81918.1 - 4.7e-32 111.1 0.0 1.1e-31 109.9 0.0 1.6 1 1 0 1 1 1 1 Sir2 family BmKX PF09132.5 KNZ81918.1 - 0.0092 15.8 0.1 0.097 12.5 0.0 2.4 2 0 0 2 2 2 1 BmKX TPP_enzyme_M PF00205.17 KNZ81918.1 - 0.019 14.7 0.1 0.55 9.9 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain 6PF2K PF01591.13 KNZ81920.1 - 2.4e-69 232.8 0.0 3.8e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Pkinase PF00069.20 KNZ81920.1 - 1.3e-29 103.1 0.0 5.5e-29 101.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain His_Phos_1 PF00300.17 KNZ81920.1 - 2.2e-28 99.3 0.0 5.1e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase_Tyr PF07714.12 KNZ81920.1 - 1.2e-08 34.3 0.0 2.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_33 PF13671.1 KNZ81920.1 - 4.1e-06 26.7 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KNZ81920.1 - 0.0073 17.1 0.0 0.023 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain Methyltransf_32 PF13679.1 KNZ81920.1 - 0.035 13.7 0.2 0.19 11.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain KTI12 PF08433.5 KNZ81920.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Protoglobin PF11563.3 KNZ81921.1 - 3.2e-48 163.3 0.0 3.7e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Protoglobin Epimerase PF01370.16 KNZ81922.1 - 0.0058 16.0 0.0 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KNZ81922.1 - 0.0092 15.2 0.1 0.022 14.0 0.1 1.6 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KNZ81922.1 - 0.02 14.9 0.0 0.059 13.3 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding ADH_zinc_N PF00107.21 KNZ81922.1 - 0.04 13.4 0.2 0.067 12.7 0.1 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Asp PF00026.18 KNZ81923.1 - 5.1e-61 206.6 0.0 6.7e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KNZ81923.1 - 1e-08 35.3 0.0 2.2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KNZ81923.1 - 3.3e-05 24.3 0.1 1.7 9.2 0.0 3.6 2 1 1 3 3 3 2 Aspartyl protease DUF285 PF03382.9 KNZ81925.1 - 0.021 14.3 1.6 0.038 13.5 1.1 1.4 1 1 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 Atg14 PF10186.4 KNZ81925.1 - 0.082 11.8 0.6 0.18 10.7 0.0 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 p450 PF00067.17 KNZ81927.1 - 2.3e-39 135.1 0.0 4.9e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 DUF2370 PF10176.4 KNZ81931.1 - 4.6e-53 179.9 0.1 6.3e-53 179.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Selenoprotein_S PF06936.6 KNZ81931.1 - 0.15 11.6 0.1 0.23 10.9 0.1 1.5 1 1 0 1 1 1 0 Selenoprotein S (SelS) p450 PF00067.17 KNZ81932.1 - 4.4e-56 190.3 0.0 8.4e-56 189.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Helitron_like_N PF14214.1 KNZ81936.1 - 2.3e-11 43.7 0.1 3.8e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Herpes_Helicase PF02689.9 KNZ81938.1 - 2.2e-06 25.7 0.0 2.3e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 Helicase ADH_zinc_N PF00107.21 KNZ81939.1 - 2e-24 85.5 0.2 3.4e-24 84.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RNase_H PF00075.19 KNZ81942.1 - 6.9e-05 23.2 0.1 0.00019 21.7 0.0 1.7 2 0 0 2 2 2 1 RNase H Aldedh PF00171.17 KNZ81943.1 - 4.3e-153 509.9 0.0 5.3e-153 509.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DnaJ_CXXCXGXG PF00684.14 KNZ81944.1 - 0.2 11.7 8.1 0.55 10.3 1.6 3.3 3 1 0 3 3 3 0 DnaJ central domain Aminotran_5 PF00266.14 KNZ81945.1 - 6.2e-50 169.9 0.0 1e-49 169.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V DXP_synthase_N PF13292.1 KNZ81946.1 - 0.022 13.6 1.2 0.024 13.5 0.8 1.0 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase CcdA PF07362.7 KNZ81946.1 - 0.49 10.2 3.2 5.2 7.0 0.1 2.2 1 1 1 2 2 2 0 Post-segregation antitoxin CcdA Transpos_assoc PF13963.1 KNZ81946.1 - 1.4 8.9 7.0 0.23 11.5 1.8 1.9 2 0 0 2 2 2 0 Transposase-associated domain TauD PF02668.11 KNZ81948.1 - 3e-53 181.1 0.4 3.4e-53 180.9 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KNZ81948.1 - 0.034 13.0 0.0 0.15 10.9 0.0 1.8 1 1 0 1 1 1 0 CsiD VRR_NUC PF08774.6 KNZ81949.1 - 6.7e-19 67.7 0.0 1.8e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 VRR-NUC domain HMG_box PF00505.14 KNZ81950.1 - 4.4e-06 26.8 0.8 9.6e-06 25.7 0.6 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box Hydrolase PF00702.21 KNZ81951.1 - 1.1e-14 55.3 0.6 3.8e-09 37.2 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KNZ81951.1 - 4e-14 53.2 0.0 1.4e-13 51.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KNZ81951.1 - 3e-11 43.1 0.0 8.5e-11 41.6 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 KNZ81951.1 - 1.7e-07 30.4 0.0 3.6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.7 KNZ81951.1 - 0.00021 20.9 1.1 0.0064 16.0 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Septin PF00735.13 KNZ81952.1 - 3.5e-109 364.1 2.6 3.5e-109 364.1 1.8 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KNZ81952.1 - 1.3e-06 28.3 0.0 4.6e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KNZ81952.1 - 2.7e-06 26.6 0.0 5.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KNZ81952.1 - 0.00033 19.8 0.0 0.00079 18.5 0.0 1.6 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 KNZ81952.1 - 0.00058 19.3 1.1 0.0089 15.4 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KNZ81952.1 - 0.004 16.9 2.4 2 8.2 0.0 2.8 2 1 1 3 3 3 2 Dynamin family ABC_tran PF00005.22 KNZ81952.1 - 0.011 16.0 0.1 0.024 14.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KNZ81952.1 - 0.041 13.4 0.1 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 KNZ81952.1 - 0.052 12.9 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Cerato-platanin PF07249.7 KNZ81953.1 - 1.2e-43 147.9 0.5 1.3e-43 147.7 0.3 1.0 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.7 KNZ81954.1 - 8.2e-25 87.1 1.3 1e-12 48.1 0.1 2.0 1 1 1 2 2 2 2 Cerato-platanin Adap_comp_sub PF00928.16 KNZ81955.1 - 8.6e-83 277.4 0.0 1.1e-82 277.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KNZ81955.1 - 7.9e-07 28.8 2.2 1.4e-06 28.1 1.6 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pentapeptide_3 PF13576.1 KNZ81955.1 - 2.2 8.2 5.0 31 4.5 0.1 3.3 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) Lipase_GDSL PF00657.17 KNZ81956.1 - 6.2e-06 26.2 0.8 1.6e-05 24.8 0.4 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KNZ81956.1 - 3.8e-05 23.8 0.0 6.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Globin PF00042.17 KNZ81956.1 - 0.033 14.5 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Globin WASH-7_N PF14745.1 KNZ81956.1 - 0.2 9.7 0.0 0.28 9.3 0.0 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal TPP_enzyme_N PF02776.13 KNZ81957.1 - 4.1e-58 195.6 0.1 1.8e-57 193.6 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KNZ81957.1 - 1.9e-48 163.8 0.2 7e-47 158.8 0.1 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KNZ81957.1 - 6e-38 129.7 0.3 1.7e-37 128.2 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Birna_VP4 PF01768.11 KNZ81957.1 - 0.023 13.7 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 Birnavirus VP4 protein Jacalin PF01419.12 KNZ81958.1 - 7e-07 29.1 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain Exo_endo_phos PF03372.18 KNZ81958.1 - 1.9e-05 24.6 1.2 3e-05 24.0 0.8 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.12 KNZ81960.1 - 5.6e-08 32.7 0.0 1.5e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Jacalin-like lectin domain Exo_endo_phos PF03372.18 KNZ81960.1 - 0.00015 21.7 0.5 0.00022 21.2 0.4 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HAD PF12710.2 KNZ81961.1 - 5.8e-14 52.6 0.0 1.6e-13 51.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KNZ81961.1 - 9.7e-14 52.2 0.0 1.2e-12 48.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KNZ81961.1 - 2.9e-13 49.4 0.0 2.9e-13 49.4 0.0 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KNZ81961.1 - 4e-11 42.7 0.0 9.4e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KNZ81961.1 - 0.0015 18.1 1.5 0.014 14.9 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_hydro_17 PF00332.13 KNZ81962.1 - 4.5e-06 25.9 0.1 1e-05 24.7 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DUF3486 PF11985.3 KNZ81966.1 - 3.4 7.6 7.8 0.18 11.8 0.6 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3486) ImpE PF07024.8 KNZ81970.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 ImpE protein RVP_2 PF08284.6 KNZ81972.1 - 0.026 14.4 0.1 0.038 13.9 0.1 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease Pkinase PF00069.20 KNZ81973.1 - 1e-11 44.5 0.0 1.6e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ81973.1 - 0.047 12.7 0.0 0.096 11.7 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Spore_GerAC PF05504.6 KNZ81974.1 - 0.0054 16.5 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 Spore germination B3/ GerAC like, C-terminal DUF4164 PF13747.1 KNZ81974.1 - 0.024 14.7 0.2 0.1 12.7 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF1504 PF07399.6 KNZ81974.1 - 0.062 11.9 0.0 0.079 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1504) MFS_1 PF07690.11 KNZ81975.1 - 8.3e-19 67.4 28.9 1e-16 60.6 9.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DAD PF02109.11 KNZ81975.1 - 0.055 13.5 0.5 0.16 12.0 0.3 1.7 1 0 0 1 1 1 0 DAD family Cofilin_ADF PF00241.15 KNZ81976.1 - 6.8e-11 42.1 0.0 7.4e-11 42.0 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Mannosyl_trans PF05007.8 KNZ81977.1 - 6.9e-75 252.0 10.6 9.7e-75 251.5 7.3 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KNZ81977.1 - 2.3e-15 56.3 3.5 2.3e-15 56.3 2.5 2.0 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U Arf PF00025.16 KNZ81978.1 - 2.6e-57 192.8 0.0 3.2e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KNZ81978.1 - 3.4e-09 35.8 0.0 1e-05 24.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KNZ81978.1 - 3.9e-09 35.9 0.0 5.1e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KNZ81978.1 - 3.5e-06 27.5 0.0 4.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KNZ81978.1 - 6.7e-06 26.0 0.0 9.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KNZ81978.1 - 2e-05 24.0 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KNZ81978.1 - 0.0012 18.0 0.0 0.0013 17.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KNZ81978.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 KNZ81979.1 - 1.6e-66 222.8 0.0 1.9e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KNZ81979.1 - 5e-10 38.8 0.0 6.6e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KNZ81979.1 - 2e-09 36.6 0.2 3.4e-06 26.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 KNZ81979.1 - 9.6e-07 28.7 0.0 3.1e-06 27.1 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KNZ81979.1 - 1.5e-06 28.6 0.0 2.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KNZ81979.1 - 6.4e-06 25.6 0.0 8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KNZ81979.1 - 0.00015 20.9 0.0 0.00018 20.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KNZ81979.1 - 0.0078 15.6 0.0 0.2 11.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KNZ81979.1 - 0.025 14.0 0.0 0.078 12.4 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation COesterase PF00135.23 KNZ81980.1 - 4.1e-103 345.9 0.0 2.1e-101 340.2 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KNZ81980.1 - 2.2e-06 27.4 0.2 1.6e-05 24.6 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KNZ81980.1 - 0.0001 21.5 0.0 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Utp21 PF04192.7 KNZ81982.1 - 3.4e-62 209.6 0.5 5.2e-62 209.0 0.3 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KNZ81982.1 - 1.1e-18 66.3 19.2 1.3e-05 24.8 0.0 9.3 10 0 0 10 10 10 5 WD domain, G-beta repeat Nup160 PF11715.3 KNZ81982.1 - 0.0049 15.0 0.3 0.12 10.4 0.1 2.9 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Hira PF07569.6 KNZ81982.1 - 0.016 14.3 1.1 28 3.8 0.0 4.7 6 0 0 6 6 6 0 TUP1-like enhancer of split Utp13 PF08625.6 KNZ81982.1 - 0.073 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.6 KNZ81982.1 - 0.31 9.7 8.8 1.3 7.6 0.4 3.7 3 2 0 4 4 4 0 Nup133 N terminal like SAPS PF04499.10 KNZ81983.1 - 2.4e-113 379.3 0.0 3.5e-113 378.7 0.0 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein FAA_hydrolase PF01557.13 KNZ81984.1 - 9.2e-57 191.9 0.0 1e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.12 KNZ81984.1 - 0.0018 17.8 0.6 0.0046 16.4 0.0 1.8 2 0 0 2 2 2 1 KH domain Amidohydro_2 PF04909.9 KNZ81985.1 - 3.7e-23 82.4 0.0 4.8e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase PAP_assoc PF03828.14 KNZ81987.1 - 1.1e-18 66.9 0.1 4.1e-18 65.0 0.1 2.1 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KNZ81987.1 - 5.6e-09 36.2 0.0 1.5e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Helitron_like_N PF14214.1 KNZ81989.1 - 3.9e-16 59.3 0.0 4.8e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.1 KNZ81990.1 - 1.8e-22 79.9 0.0 2.4e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Gemini_AL1 PF00799.15 KNZ81990.1 - 0.081 12.7 0.5 0.12 12.2 0.3 1.4 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain DUF3296 PF11726.3 KNZ81990.1 - 0.16 11.5 0.5 0.2 11.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) PIF1 PF05970.9 KNZ81992.1 - 2.4e-39 135.3 0.0 2.7e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ81992.1 - 0.0012 18.4 0.0 0.0015 18.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ81992.1 - 0.0089 16.0 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.10 KNZ81992.1 - 0.014 15.2 0.0 0.034 13.9 0.0 1.6 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.11 KNZ81992.1 - 0.059 12.5 0.0 0.11 11.7 0.0 1.4 2 0 0 2 2 2 0 PhoH-like protein Viral_helicase1 PF01443.13 KNZ81992.1 - 0.067 12.6 0.2 0.09 12.2 0.1 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KNZ81992.1 - 0.09 12.9 0.1 0.49 10.5 0.1 2.0 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KNZ81992.1 - 0.11 11.8 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain CENP-C_C PF11699.3 KNZ81993.1 - 2.3e-15 56.3 0.0 4.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 KNZ81993.1 - 0.0077 15.7 0.1 0.018 14.5 0.1 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KNZ81993.1 - 0.012 14.9 0.1 0.027 13.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.14 KNZ81993.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Herpes_UL32 PF06070.6 KNZ81993.1 - 0.37 9.1 7.3 0.47 8.8 5.0 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 KAR9 PF08580.5 KNZ81993.1 - 0.57 8.3 7.6 0.71 8.0 5.3 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 CTP_transf_1 PF01148.15 KNZ81994.1 - 1.5e-08 34.6 2.8 3.1e-08 33.5 2.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase family DUF1938 PF09153.5 KNZ81995.1 - 0.14 12.0 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) RNase_H PF00075.19 KNZ81997.1 - 6.1e-06 26.6 0.0 1.4e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 RNase H TRAPPC-Trs85 PF12739.2 KNZ81998.1 - 0.018 13.7 0.0 0.018 13.7 0.0 1.0 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit P4Ha_N PF08336.6 KNZ81998.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Globin PF00042.17 KNZ81998.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Globin Myb_DNA-bind_2 PF08914.6 KNZ82000.1 - 0.02 14.6 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Rap1 Myb domain NRDD PF13597.1 KNZ82000.1 - 0.075 11.1 0.3 0.081 10.9 0.2 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase SecD_SecF PF02355.11 KNZ82000.1 - 0.44 9.7 4.7 1.3 8.1 0.3 2.2 2 0 0 2 2 2 0 Protein export membrane protein Orn_Arg_deC_N PF02784.11 KNZ82001.1 - 1.1e-69 234.3 0.0 1.5e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KNZ82001.1 - 6.2e-30 103.3 0.0 1.1e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Mlf1IP PF10248.4 KNZ82001.1 - 0.22 11.1 0.3 0.41 10.2 0.2 1.4 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Ribosomal_S17e PF00833.13 KNZ82002.1 - 6.7e-43 145.3 0.0 2.3e-42 143.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal S17 zf-C2H2 PF00096.21 KNZ82002.1 - 3.7e-05 23.8 1.4 0.17 12.2 0.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ82002.1 - 0.00075 19.6 2.4 0.099 13.0 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KNZ82002.1 - 0.0008 19.4 0.5 0.16 12.1 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KNZ82002.1 - 0.094 12.8 1.6 5.9 7.1 1.7 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_S8 PF00410.14 KNZ82003.1 - 5.1e-27 94.2 0.1 7.2e-27 93.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Orn_Arg_deC_N PF02784.11 KNZ82004.1 - 3.8e-69 232.6 0.0 5.1e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KNZ82004.1 - 5.2e-30 103.5 0.0 9.2e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain G-alpha PF00503.15 KNZ82005.1 - 8.1e-120 400.0 0.0 9.8e-120 399.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KNZ82005.1 - 8e-15 54.5 0.4 4.2e-09 35.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KNZ82005.1 - 0.0013 17.9 0.0 0.58 9.2 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KNZ82005.1 - 0.022 15.2 0.1 1 9.8 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 KNZ82005.1 - 0.04 13.4 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KNZ82005.1 - 0.1 12.0 0.0 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TPR_10 PF13374.1 KNZ82006.1 - 5.3e-115 372.5 0.3 5.4e-10 38.8 0.0 14.9 14 1 0 14 14 14 13 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ82006.1 - 1.8e-78 258.5 15.8 4.6e-11 42.4 0.0 9.7 2 2 4 9 9 9 9 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ82006.1 - 6.2e-18 63.4 1.4 1.9 8.8 0.0 11.7 12 0 0 12 12 12 2 Tetratricopeptide repeat Patatin PF01734.17 KNZ82006.1 - 4.4e-14 52.9 0.0 1.4e-13 51.2 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_16 PF13432.1 KNZ82006.1 - 9e-14 51.7 5.5 0.00075 20.1 0.1 7.9 3 2 5 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ82006.1 - 7.2e-12 45.4 37.6 0.046 14.0 0.9 11.1 6 4 7 13 13 13 7 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ82006.1 - 3.2e-10 39.0 13.6 0.32 10.8 0.0 9.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ82006.1 - 7e-10 38.0 26.4 1.4 9.0 0.2 10.9 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_3 PF07720.7 KNZ82006.1 - 1.1e-06 28.3 12.5 3 7.7 0.1 9.3 10 0 0 10 10 10 1 Tetratricopeptide repeat NB-ARC PF00931.17 KNZ82006.1 - 1.4e-05 24.1 8.0 0.0018 17.1 0.1 3.1 2 1 1 3 3 3 2 NB-ARC domain DUF4404 PF14357.1 KNZ82006.1 - 1.6e-05 25.1 21.4 1.4 9.4 0.0 9.0 3 3 6 9 9 9 1 Domain of unknown function (DUF4404) DUF2664 PF10867.3 KNZ82006.1 - 1.8e-05 25.2 19.1 8.9 7.0 0.1 8.6 6 2 1 7 7 7 0 Protein of unknown function (DUF2664) AAA_22 PF13401.1 KNZ82006.1 - 0.0004 20.5 0.0 0.003 17.7 0.0 2.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ82006.1 - 0.006 16.5 2.9 0.011 15.7 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain TPR_20 PF14561.1 KNZ82006.1 - 0.021 14.9 24.6 1.6 8.8 0.8 8.9 4 2 4 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ82006.1 - 0.025 14.1 18.1 24 4.7 0.0 9.6 11 0 0 11 11 11 0 Tetratricopeptide repeat SSI PF00720.12 KNZ82006.1 - 0.035 14.0 4.4 17 5.4 0.0 5.2 3 2 2 6 6 6 0 Subtilisin inhibitor-like TPR_4 PF07721.9 KNZ82006.1 - 0.063 13.7 16.5 55 4.6 0.0 8.6 9 0 0 9 9 8 0 Tetratricopeptide repeat PH PF00169.24 KNZ82007.1 - 0.00045 20.3 0.0 0.00091 19.3 0.0 1.6 1 0 0 1 1 1 1 PH domain Orthopox_A5L PF06193.6 KNZ82007.1 - 0.041 13.8 4.2 0.042 13.7 0.3 2.2 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like DUF913 PF06025.7 KNZ82007.1 - 0.59 8.8 4.5 0.34 9.6 0.6 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) NOA36 PF06524.7 KNZ82007.1 - 2.1 7.5 5.1 3.3 6.8 3.6 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 KNZ82007.1 - 4.3 6.8 10.3 8.8 5.8 7.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin Pho88 PF10032.4 KNZ82008.1 - 4.3e-67 225.0 0.2 4.7e-67 224.9 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) TPR_10 PF13374.1 KNZ82009.1 - 5.3e-95 309.0 0.4 2.9e-10 39.7 0.1 13.0 12 1 0 12 12 12 11 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ82009.1 - 2.1e-75 248.6 33.8 3.4e-11 42.9 0.1 8.7 3 2 8 11 11 10 10 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ82009.1 - 3.4e-19 67.3 0.1 1.2 9.4 0.0 11.9 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ82009.1 - 3.9e-18 65.5 26.0 0.048 14.0 0.1 11.0 2 2 10 12 12 12 6 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ82009.1 - 9.9e-18 64.3 0.0 0.21 12.2 0.0 7.6 3 2 6 9 9 9 4 Tetratricopeptide repeat Patatin PF01734.17 KNZ82009.1 - 8.3e-14 51.9 0.1 2.8e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase TPR_2 PF07719.12 KNZ82009.1 - 5.5e-11 41.5 14.5 6.8 6.8 0.0 10.6 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_3 PF07720.7 KNZ82009.1 - 1.2e-10 40.9 9.0 0.051 13.3 0.0 8.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_4 PF07721.9 KNZ82009.1 - 1.3e-06 28.2 13.1 5.3 7.7 0.0 9.1 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF4404 PF14357.1 KNZ82009.1 - 2.7e-06 27.7 30.9 0.74 10.2 0.3 9.6 4 2 7 11 11 11 4 Domain of unknown function (DUF4404) TPR_7 PF13176.1 KNZ82009.1 - 5.2e-06 25.8 15.0 0.39 10.6 0.0 8.4 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_20 PF14561.1 KNZ82009.1 - 8.8e-06 25.7 20.7 6.1 7.0 0.0 9.5 2 2 5 8 8 8 1 Tetratricopeptide repeat SSI PF00720.12 KNZ82009.1 - 8.1e-05 22.4 5.2 3 7.8 0.0 5.6 3 1 0 5 5 5 1 Subtilisin inhibitor-like TPR_1 PF00515.23 KNZ82009.1 - 0.00014 21.3 14.0 5.6 6.7 0.0 9.3 12 0 0 12 12 12 1 Tetratricopeptide repeat PPR PF01535.15 KNZ82009.1 - 0.0095 15.8 5.6 11 6.2 0.0 6.7 8 0 0 8 8 7 0 PPR repeat TPR_6 PF13174.1 KNZ82009.1 - 0.023 15.1 41.2 11 6.7 0.0 12.0 12 0 0 12 12 12 0 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ82009.1 - 0.075 13.7 18.3 38 5.2 0.1 9.1 8 2 3 11 11 10 0 Tetratricopeptide repeat Pho88 PF10032.4 KNZ82010.1 - 2.7e-25 88.7 0.1 3.1e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) TPR_10 PF13374.1 KNZ82011.1 - 3.3e-131 424.0 5.5 7.8e-10 38.3 0.2 15.5 15 0 0 15 15 15 15 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ82011.1 - 4.3e-90 295.7 26.9 3.3e-14 52.5 0.5 9.5 6 1 5 11 11 10 10 Tetratricopeptide repeat TPR_17 PF13431.1 KNZ82011.1 - 1.3e-27 93.6 0.4 3 8.2 0.0 14.4 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ82011.1 - 8.8e-24 83.6 33.0 0.0035 17.6 0.0 12.0 3 3 10 13 13 13 9 Tetratricopeptide repeat TPR_16 PF13432.1 KNZ82011.1 - 7.9e-21 74.1 7.4 0.0067 17.0 0.0 8.0 6 2 1 8 8 8 5 Tetratricopeptide repeat Patatin PF01734.17 KNZ82011.1 - 7.2e-14 52.1 0.2 2.7e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase TPR_4 PF07721.9 KNZ82011.1 - 1.9e-09 37.0 10.1 0.66 10.5 0.0 11.2 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_3 PF07720.7 KNZ82011.1 - 2.2e-09 36.9 17.6 0.19 11.5 0.1 9.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ82011.1 - 3.6e-09 35.8 31.8 2 8.5 0.1 12.6 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ82011.1 - 4.9e-09 35.3 12.0 0.69 9.8 0.0 8.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_20 PF14561.1 KNZ82011.1 - 7.2e-09 35.6 30.8 0.11 12.6 0.2 11.1 2 2 6 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.23 KNZ82011.1 - 7.9e-06 25.2 14.3 2.9 7.6 0.0 10.3 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_5 PF12688.2 KNZ82011.1 - 1.1e-05 25.3 31.8 0.27 11.2 1.4 8.9 1 1 9 11 11 11 3 Tetratrico peptide repeat DUF4404 PF14357.1 KNZ82011.1 - 1.8e-05 25.0 34.0 1.5 9.2 0.1 10.8 4 3 8 12 12 12 2 Domain of unknown function (DUF4404) DUF367 PF04034.8 KNZ82011.1 - 0.00028 20.4 5.8 2.7 7.6 0.0 7.1 6 2 2 8 8 8 1 Domain of unknown function (DUF367) TPR_8 PF13181.1 KNZ82011.1 - 0.0018 17.8 22.1 19 5.3 0.0 10.9 13 0 0 13 13 11 0 Tetratricopeptide repeat SSI PF00720.12 KNZ82011.1 - 0.019 14.8 10.7 18 5.3 0.0 6.3 4 3 3 7 7 7 0 Subtilisin inhibitor-like TPR_6 PF13174.1 KNZ82011.1 - 0.032 14.6 51.4 8.4 7.0 0.1 13.2 14 0 0 14 14 12 0 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ82011.1 - 0.59 10.9 26.7 22 6.0 0.6 10.5 8 4 5 13 13 11 0 Tetratricopeptide repeat Glyco_hydro_12 PF01670.11 KNZ82012.1 - 3e-35 121.3 2.0 3e-35 121.3 1.4 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 Suf PF05843.9 KNZ82013.1 - 0.18 11.4 1.2 0.28 10.8 0.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-CCHC_3 PF13917.1 KNZ82013.1 - 0.43 10.3 6.7 1 9.1 4.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Phage_integrase PF00589.17 KNZ82014.1 - 0.06 13.0 0.0 0.075 12.6 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family Zn_peptidase PF04228.8 KNZ82015.1 - 0.074 12.2 0.0 0.097 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase F-box-like PF12937.2 KNZ82018.1 - 2.6e-07 30.2 1.7 2e-06 27.4 0.2 3.0 2 1 0 2 2 2 1 F-box-like PIF1 PF05970.9 KNZ82021.1 - 6.4e-30 104.3 0.0 7.5e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase PX PF00787.19 KNZ82023.1 - 2e-25 88.7 0.0 2.8e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 PX domain FLYWCH PF04500.11 KNZ82024.1 - 0.019 14.8 0.3 0.038 13.8 0.2 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain Y_phosphatase3 PF13350.1 KNZ82025.1 - 2.8e-34 118.7 0.0 6.2e-34 117.6 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KNZ82025.1 - 2.8e-13 49.7 0.0 6e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 KNZ82025.1 - 3.3e-05 23.3 0.0 4.6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KNZ82025.1 - 0.00064 19.3 0.0 0.0016 18.0 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DUF1382 PF07131.6 KNZ82025.1 - 0.0062 16.6 0.2 1.9 8.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1382) Y_phosphatase2 PF03162.8 KNZ82025.1 - 0.009 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KNZ82025.1 - 0.014 15.4 0.1 0.025 14.6 0.0 1.6 1 1 0 1 1 1 0 Inositol hexakisphosphate Annexin PF00191.15 KNZ82026.1 - 7.4e-47 157.1 3.4 4.4e-13 48.9 0.2 4.4 4 1 0 4 4 4 4 Annexin Pkinase PF00069.20 KNZ82027.1 - 4.6e-10 39.0 0.0 7.2e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KNZ82027.1 - 6.4e-05 22.7 0.6 0.00014 21.7 0.4 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KNZ82027.1 - 7.9e-05 21.8 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KNZ82027.1 - 0.00041 19.4 0.0 0.00072 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KNZ82027.1 - 0.0052 15.7 0.0 0.0081 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KNZ82027.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 2OG-FeII_Oxy PF03171.15 KNZ82028.1 - 8e-17 61.3 0.0 1.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KNZ82028.1 - 1.1e-07 32.4 0.2 2.2e-07 31.4 0.2 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF2484 PF10658.4 KNZ82029.1 - 0.27 11.3 2.6 0.61 10.2 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) F-box-like PF12937.2 KNZ82031.1 - 0.0012 18.4 0.2 0.0029 17.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ82031.1 - 0.024 14.2 0.2 0.093 12.4 0.1 2.0 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.2 KNZ82032.1 - 0.11 12.1 4.8 3.5 7.3 0.0 4.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) DcpS_C PF11969.3 KNZ82033.1 - 1.2e-26 93.2 0.0 2e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KNZ82033.1 - 3.4e-18 66.0 0.0 6.2e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HSA PF07529.8 KNZ82036.1 - 0.16 11.7 2.7 0.13 12.1 0.8 1.6 2 0 0 2 2 2 0 HSA Glyco_hydro_12 PF01670.11 KNZ82037.1 - 0.047 13.4 0.1 2.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 12 MYCBPAP PF14646.1 KNZ82037.1 - 0.12 11.1 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 MYCBP-associated protein family Sec2p PF06428.6 KNZ82038.1 - 8.2e-12 44.8 4.8 8.2e-12 44.8 3.3 2.0 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p HR1 PF02185.11 KNZ82038.1 - 0.053 13.2 13.6 0.15 11.8 9.4 1.8 1 0 0 1 1 1 0 Hr1 repeat Tmemb_cc2 PF10267.4 KNZ82038.1 - 0.16 10.5 11.3 0.061 11.9 2.2 2.2 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Vmethyltransf_C PF08456.5 KNZ82038.1 - 1 8.7 5.1 0.39 10.0 0.1 2.1 2 0 0 2 2 2 0 Viral methyltransferase C-terminal V_ATPase_I PF01496.14 KNZ82038.1 - 1.1 7.0 4.6 2 6.1 0.2 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 KNZ82038.1 - 2.1 7.4 7.3 7.1 5.7 0.2 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Mucin PF01456.12 KNZ82038.1 - 3.5 7.3 14.6 0.62 9.8 0.3 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein APH PF01636.18 KNZ82039.1 - 6.9e-06 25.9 0.1 1.7e-05 24.7 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KNZ82039.1 - 0.0097 14.5 0.0 0.032 12.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) TPR_10 PF13374.1 KNZ82039.1 - 0.2 11.6 1.3 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-CCHC_2 PF13696.1 KNZ82040.1 - 0.15 11.5 3.0 21 4.7 2.1 2.4 1 1 0 1 1 1 0 Zinc knuckle WD40 PF00400.27 KNZ82041.1 - 8.8e-35 117.3 8.0 2.2e-10 39.9 0.0 5.5 4 1 1 5 5 5 5 WD domain, G-beta repeat PQQ_2 PF13360.1 KNZ82041.1 - 0.046 13.1 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain DPPIV_N PF00930.16 KNZ82041.1 - 0.072 11.6 0.1 8.7 4.8 0.0 2.8 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 KNZ82041.1 - 0.085 12.5 0.1 22 4.8 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Z1 PF10593.4 KNZ82041.1 - 0.14 11.3 0.1 0.81 8.8 0.0 1.9 1 1 0 2 2 2 0 Z1 domain Terpene_synth_C PF03936.11 KNZ82043.1 - 5.2e-16 58.6 0.1 6.6e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Sensor PF13796.1 KNZ82045.1 - 9.1e-07 28.6 9.2 1.5e-06 27.9 5.6 2.0 1 1 1 2 2 2 2 Putative sensor Cyt-b5 PF00173.23 KNZ82046.1 - 3.3e-10 39.6 0.0 4e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_M20 PF01546.23 KNZ82047.1 - 1.1e-09 38.0 1.4 2.6e-09 36.8 1.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KNZ82047.1 - 9.1e-07 28.6 0.0 2.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Ricin_B_lectin PF00652.17 KNZ82048.1 - 4.5e-20 71.9 0.6 7.1e-20 71.2 0.4 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KNZ82048.1 - 1.1e-18 67.4 1.7 5.7e-10 39.5 0.5 3.3 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like adh_short PF00106.20 KNZ82049.1 - 4.8e-14 52.6 0.0 9.5e-14 51.6 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KNZ82049.1 - 2.3e-06 27.3 0.0 9e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KNZ82049.1 - 2.4e-05 24.2 0.0 3.5e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase R3H PF01424.17 KNZ82050.1 - 1.3e-09 37.5 0.0 3.9e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 KNZ82050.1 - 5.4e-07 29.3 0.3 1.3e-06 28.1 0.2 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KNZ82050.1 - 0.0024 17.6 0.4 0.0024 17.6 0.3 3.0 4 0 0 4 4 4 1 DExH-box splicing factor binding site Glyco_hydro_71 PF03659.9 KNZ82051.1 - 2.3e-89 299.6 2.7 2.3e-89 299.6 1.9 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 WSC PF01822.14 KNZ82051.1 - 6e-19 67.7 8.6 6e-19 67.7 6.0 1.8 2 0 0 2 2 2 1 WSC domain RWD PF05773.17 KNZ82051.1 - 0.078 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain Toxin_3 PF00537.13 KNZ82051.1 - 0.95 9.3 7.7 0.048 13.5 1.3 1.7 2 0 0 2 2 2 0 Scorpion toxin-like domain Ferritin_2 PF13668.1 KNZ82053.1 - 1.2e-35 122.4 0.1 1.8e-35 121.8 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Glyoxalase PF00903.20 KNZ82054.1 - 2.1e-25 89.1 0.1 2.4e-25 88.9 0.1 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KNZ82054.1 - 4.6e-18 65.7 0.0 6.2e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KNZ82054.1 - 8.6e-09 35.3 0.0 1.6e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KNZ82054.1 - 0.0062 16.4 0.0 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase-like domain CppA_N PF14506.1 KNZ82054.1 - 0.055 13.1 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal AAA_8 PF12780.2 KNZ82055.1 - 0.003 16.5 0.0 0.0042 16.0 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 PLAC9 PF15205.1 KNZ82056.1 - 0.0081 16.4 0.1 0.042 14.1 0.1 2.2 1 1 1 2 2 2 1 Placenta-specific protein 9 DZR PF12773.2 KNZ82056.1 - 0.23 11.2 1.6 0.54 10.1 1.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon Sgf11 PF08209.6 KNZ82056.1 - 0.35 10.2 0.8 0.85 8.9 0.0 1.9 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) NPV_P10 PF05531.7 KNZ82056.1 - 1.7 8.9 10.8 20 5.4 0.1 5.0 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein LRR_4 PF12799.2 KNZ82060.1 - 4.4e-57 188.9 64.4 1.3e-08 34.2 0.5 13.5 7 3 7 16 16 16 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNZ82060.1 - 2.1e-48 161.9 58.9 3.6e-11 42.6 1.2 10.0 7 2 4 11 11 11 8 Leucine rich repeat PP2C PF00481.16 KNZ82060.1 - 5.5e-40 137.3 0.0 8.9e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.28 KNZ82060.1 - 1.3e-26 88.5 65.3 0.17 12.0 0.2 20.3 21 0 0 21 21 21 10 Leucine Rich Repeat LRR_7 PF13504.1 KNZ82060.1 - 5.1e-20 68.0 58.6 0.56 10.6 0.1 20.0 21 0 0 21 21 21 7 Leucine rich repeat Guanylate_cyc PF00211.15 KNZ82060.1 - 1.2e-19 70.3 0.0 2.1e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_6 PF13516.1 KNZ82060.1 - 4.2e-05 23.1 60.5 5.8 7.3 0.0 17.2 18 2 1 19 19 19 3 Leucine Rich repeat DUF4119 PF13494.1 KNZ82060.1 - 0.096 12.6 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) Toxin_32 PF08120.6 KNZ82060.1 - 6 6.5 5.6 2.2 7.9 0.3 2.6 3 0 0 3 3 3 0 Tamulustoxin family Mg_trans_NIPA PF05653.9 KNZ82061.1 - 4.5e-82 275.3 28.0 6.5e-82 274.8 19.4 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KNZ82061.1 - 1.8e-07 31.2 12.8 1.8e-07 31.2 8.9 3.8 2 2 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 KNZ82061.1 - 1.1e-06 28.8 9.8 1.1e-06 28.8 6.8 3.6 2 2 1 3 3 3 1 Multidrug resistance efflux transporter Glyco_hydro_2_C PF02836.12 KNZ82062.1 - 0.041 12.7 0.2 0.089 11.6 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KNZ82062.1 - 0.045 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 Herpes_BLLF1 PF05109.8 KNZ82063.1 - 0.24 9.3 29.3 0.31 8.9 20.3 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DPBB_1 PF03330.13 KNZ82064.1 - 0.0021 18.0 0.0 0.0042 17.0 0.0 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KNZ82064.1 - 0.0029 17.2 0.1 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 Barwin family SH3_9 PF14604.1 KNZ82065.1 - 3.9e-25 87.1 0.9 6.3e-13 48.0 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 KNZ82065.1 - 5.9e-23 80.1 0.1 7.7e-11 41.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KNZ82065.1 - 4.8e-21 73.8 0.1 8.1e-10 37.9 0.0 2.6 2 0 0 2 2 2 2 SH3 domain FCH PF00611.18 KNZ82065.1 - 3.5e-11 43.1 0.4 3.5e-11 43.1 0.3 3.5 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.17 KNZ82065.1 - 1.3e-10 40.8 4.5 2.2e-10 40.1 3.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.6 KNZ82065.1 - 0.00035 20.6 1.4 0.00063 19.8 0.1 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain Cep57_MT_bd PF06657.8 KNZ82065.1 - 0.1 12.5 9.1 0.34 10.9 0.7 3.2 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF1789 PF08748.6 KNZ82065.1 - 1.9 8.6 7.7 0.49 10.4 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1789) Herpes_UL55 PF04537.7 KNZ82065.1 - 2.5 7.4 7.8 0.33 10.3 1.2 2.4 2 1 1 3 3 3 0 Herpesvirus UL55 protein CAF1 PF04857.15 KNZ82066.1 - 7.6e-64 215.5 0.0 1.3e-63 214.7 0.0 1.4 1 1 0 1 1 1 1 CAF1 family ribonuclease RNase_H_2 PF13482.1 KNZ82066.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 RNase_H superfamily EBP PF05241.7 KNZ82067.1 - 1.5e-63 213.3 6.6 1.8e-63 213.0 4.5 1.0 1 0 0 1 1 1 1 Emopamil binding protein 7tm_1 PF00001.16 KNZ82067.1 - 0.01 14.9 0.9 0.02 14.0 0.1 1.8 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Fungal_trans PF04082.13 KNZ82068.1 - 6.1e-17 61.3 0.2 1e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3292 PF11696.3 KNZ82068.1 - 0.29 8.9 0.4 0.54 8.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) Fungal_trans PF04082.13 KNZ82069.1 - 1.9e-12 46.5 0.1 4.4e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ82069.1 - 1.7 8.5 5.6 3.2 7.7 3.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CMAS PF02353.15 KNZ82070.1 - 2.7e-60 203.7 0.0 4.1e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KNZ82070.1 - 1.2e-10 41.9 0.0 1.9e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ82070.1 - 2.8e-05 23.5 0.0 4.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KNZ82070.1 - 6.6e-05 22.5 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 KNZ82070.1 - 7.6e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_12 PF08242.7 KNZ82070.1 - 0.00016 22.1 0.0 0.00032 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KNZ82070.1 - 0.00018 21.2 0.0 0.00036 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ82070.1 - 0.00036 20.5 0.0 0.00062 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KNZ82070.1 - 0.00063 19.3 0.0 0.00097 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 KNZ82070.1 - 0.00064 20.5 0.0 0.0015 19.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KNZ82070.1 - 0.00096 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.4 KNZ82070.1 - 0.0082 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_3 PF01596.12 KNZ82070.1 - 0.034 13.1 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DUF938 PF06080.7 KNZ82070.1 - 0.041 13.4 0.1 0.088 12.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF938) DUF427 PF04248.7 KNZ82072.1 - 8.9e-29 99.0 3.4 1.1e-28 98.7 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF427) PRiA4_ORF3 PF07929.6 KNZ82072.1 - 2.3e-09 36.9 0.7 5.7e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Plasmid pRiA4b ORF-3-like protein GPI-anchored PF10342.4 KNZ82073.1 - 3.6e-05 24.1 0.0 4.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.4 KNZ82074.1 - 0.13 12.7 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3050 PF11251.3 KNZ82075.1 - 0.052 12.7 0.0 1.7 7.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3050) AMP-binding PF00501.23 KNZ82076.1 - 6.2e-25 87.4 0.0 7.8e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 KNZ82077.1 - 9.5e-29 100.0 0.0 1.1e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KNZ82077.1 - 4.3e-12 46.8 0.0 8.5e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 KNZ82078.1 - 1e-41 142.6 0.1 4.4e-20 71.4 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KNZ82078.1 - 9e-12 45.7 0.1 2.3e-11 44.4 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3132 PF11330.3 KNZ82078.1 - 0.11 12.3 0.1 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3132) LEDGF PF11467.3 KNZ82079.1 - 0.22 11.2 1.4 0.51 10.0 0.0 2.3 3 0 0 3 3 3 0 Lens epithelium-derived growth factor (LEDGF) UQ_con PF00179.21 KNZ82081.1 - 1.8e-41 140.8 0.0 2.2e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 KNZ82081.1 - 8.9e-20 70.0 0.1 1.6e-19 69.1 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 KNZ82081.1 - 0.00077 19.2 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Peptidase_S10 PF00450.17 KNZ82082.1 - 4.5e-90 302.7 1.0 5.7e-90 302.4 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_5 PF12695.2 KNZ82082.1 - 0.045 13.4 0.0 0.13 11.9 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family DFP PF04127.10 KNZ82083.1 - 0.038 13.5 1.6 0.069 12.7 1.1 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.11 KNZ82084.1 - 3.2e-26 91.8 78.4 9.6e-24 83.7 27.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EB1 PF03271.12 KNZ82085.1 - 5.4e-16 58.3 2.5 1e-15 57.4 1.7 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 KNZ82085.1 - 1.3e-07 31.5 0.2 2e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.11 KNZ82085.1 - 0.0014 16.9 0.0 0.0021 16.3 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like Suppressor_APC PF11414.3 KNZ82085.1 - 0.08 12.7 0.8 0.14 11.9 0.5 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Peptidase_S10 PF00450.17 KNZ82087.1 - 2e-94 317.1 5.0 2.4e-94 316.8 3.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ank_2 PF12796.2 KNZ82092.1 - 1.1e-118 387.8 23.3 3.9e-26 91.2 0.1 5.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ82092.1 - 8.6e-91 293.5 0.5 8e-10 38.0 0.0 9.1 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.1 KNZ82092.1 - 6.2e-74 242.3 20.4 1.6e-13 50.3 0.2 7.5 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 KNZ82092.1 - 2.2e-65 215.9 6.1 1.5e-10 41.2 0.0 8.5 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ82092.1 - 4.3e-55 178.1 2.8 3.5e-05 23.6 0.0 9.0 9 0 0 9 9 9 8 Ankyrin repeat DUF4115 PF13464.1 KNZ82092.1 - 0.00014 21.4 0.4 20 4.9 0.0 5.6 4 2 2 6 6 6 0 Domain of unknown function (DUF4115) DUF3581 PF12119.3 KNZ82092.1 - 0.0002 20.6 5.4 0.088 12.0 0.0 4.4 1 1 4 5 5 5 2 Protein of unknown function (DUF3581) AMNp_N PF10423.4 KNZ82092.1 - 0.00036 20.1 0.0 3.9 7.0 0.0 4.4 4 1 1 5 5 5 1 Bacterial AMP nucleoside phosphorylase N-terminus rve PF00665.21 KNZ82092.1 - 0.045 13.8 0.3 7.3 6.7 0.1 2.9 2 1 0 3 3 3 0 Integrase core domain BCS1_N PF08740.6 KNZ82092.1 - 0.048 13.2 0.1 7.3 6.1 0.0 3.6 2 2 3 5 5 5 0 BCS1 N terminal Tail_tube PF10618.4 KNZ82092.1 - 0.55 9.9 5.4 25 4.6 0.0 4.6 3 1 2 5 5 5 0 Phage tail tube protein Pput2613-deam PF14427.1 KNZ82092.1 - 4.2 7.0 10.8 25 4.5 0.0 5.4 4 2 2 6 6 6 0 Pput_2613-like deaminase Ank PF00023.25 KNZ82093.1 - 3.9e-84 272.5 12.3 1.8e-09 36.8 0.1 11.1 10 1 0 10 10 10 10 Ankyrin repeat Ank_2 PF12796.2 KNZ82093.1 - 1.2e-81 269.1 32.2 7.8e-22 77.4 1.7 6.1 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KNZ82093.1 - 1.8e-57 190.0 8.0 3e-11 43.1 0.0 8.7 2 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 KNZ82093.1 - 3.4e-57 189.8 9.1 5.4e-12 45.8 0.0 8.2 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ82093.1 - 1.2e-48 158.2 12.6 4.9e-05 23.1 0.0 10.6 10 0 0 10 10 10 9 Ankyrin repeat BCS1_N PF08740.6 KNZ82093.1 - 0.057 13.0 1.0 16 5.0 0.0 4.2 3 1 1 5 5 5 0 BCS1 N terminal Methyltransf_23 PF13489.1 KNZ82095.1 - 1.8e-17 63.5 0.0 2.4e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KNZ82095.1 - 7.3e-14 52.0 0.0 1.2e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KNZ82095.1 - 2.3e-12 46.7 0.0 2.7e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ82095.1 - 2.7e-11 43.8 0.0 5.5e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ82095.1 - 2.8e-11 43.9 0.0 2.5e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KNZ82095.1 - 2.4e-07 31.0 0.0 7.6e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KNZ82095.1 - 7.1e-07 29.2 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KNZ82095.1 - 1.1e-06 27.8 0.0 2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 KNZ82095.1 - 0.00012 21.2 0.0 0.00047 19.3 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KNZ82095.1 - 0.0002 20.8 0.0 0.00034 20.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KNZ82095.1 - 0.0019 18.1 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 KNZ82095.1 - 0.0024 17.0 0.0 0.0032 16.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 KNZ82095.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF938) CheR PF01739.13 KNZ82095.1 - 0.032 13.5 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.4 KNZ82095.1 - 0.057 12.8 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 KNZ82095.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AXE1 PF05448.7 KNZ82096.1 - 0.0039 15.7 0.4 0.0065 15.0 0.1 1.4 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF3809 PF12723.2 KNZ82096.1 - 0.0088 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3809) DUF463 PF04317.7 KNZ82096.1 - 0.11 11.0 0.3 0.15 10.5 0.2 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 TylF PF05711.6 KNZ82096.1 - 0.16 10.9 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) DUF2396 PF09654.5 KNZ82099.1 - 0.077 12.9 0.4 0.16 11.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) MFS_1 PF07690.11 KNZ82101.1 - 3.2e-32 111.6 41.7 3.6e-32 111.4 25.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Coq4 PF05019.8 KNZ82101.1 - 0.16 10.8 0.0 0.35 9.7 0.0 1.5 1 0 0 1 1 1 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DUF3671 PF12420.3 KNZ82101.1 - 4.5 7.2 8.9 22 5.0 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function Asp_protease_2 PF13650.1 KNZ82104.1 - 0.0032 17.9 0.0 0.0058 17.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KNZ82104.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 KNZ82104.1 - 0.091 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease GvpH PF05455.6 KNZ82105.1 - 0.032 13.8 0.4 0.076 12.6 0.0 1.8 2 1 0 3 3 3 0 GvpH RNase_H PF00075.19 KNZ82106.1 - 3.2e-11 43.6 0.0 6.4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 RNase H Zn_Tnp_IS1595 PF12760.2 KNZ82106.1 - 0.0091 15.7 2.2 0.014 15.2 0.2 2.2 2 0 0 2 2 2 1 Transposase zinc-ribbon domain COG5 PF10392.4 KNZ82107.1 - 0.22 11.4 1.9 13 5.7 1.3 2.3 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Chromo PF00385.19 KNZ82112.1 - 0.0028 17.2 0.2 0.0043 16.6 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain tRNA_lig_CPD PF08302.6 KNZ82112.1 - 0.045 12.9 0.0 0.082 12.1 0.0 1.4 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain GMC_oxred_C PF05199.8 KNZ82114.1 - 2.2e-09 37.7 0.0 7.9e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KNZ82114.1 - 1.9e-05 23.9 0.0 8e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_3 PF01494.14 KNZ82114.1 - 0.0077 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 KNZ82114.1 - 0.074 12.6 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribonuc_L-PSP PF01042.16 KNZ82114.1 - 0.082 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease L-PSP Pyr_redox_2 PF07992.9 KNZ82114.1 - 0.088 12.6 0.0 0.32 10.8 0.0 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KNZ82114.1 - 0.096 11.5 0.1 0.3 9.9 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 KNZ82114.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Myc-LZ PF02344.10 KNZ82114.1 - 0.42 10.2 2.2 2.9 7.6 1.6 2.1 2 0 0 2 2 2 0 Myc leucine zipper domain VCBS PF13517.1 KNZ82115.1 - 1 9.7 5.2 6.3 7.2 0.4 3.7 3 1 1 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BTB PF00651.26 KNZ82116.1 - 0.0024 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain p450 PF00067.17 KNZ82117.1 - 1.1e-63 215.3 0.0 1.3e-63 215.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Helitron_like_N PF14214.1 KNZ82120.1 - 3.8e-18 65.8 0.2 5.4e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ82120.1 - 0.023 14.2 0.1 0.042 13.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3296) Gemini_AL1 PF00799.15 KNZ82120.1 - 0.088 12.6 0.6 0.23 11.2 0.1 1.9 2 0 0 2 2 2 0 Geminivirus Rep catalytic domain PIF1 PF05970.9 KNZ82122.1 - 2.4e-88 296.5 0.0 2.7e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase ChaC PF04752.7 KNZ82124.1 - 1.4e-37 129.4 0.1 3.2e-33 115.1 0.0 2.0 1 1 1 2 2 2 2 ChaC-like protein AIG2 PF06094.7 KNZ82124.1 - 0.013 15.9 0.0 0.019 15.4 0.0 1.2 1 0 0 1 1 1 0 AIG2-like family Aminotran_4 PF01063.14 KNZ82125.1 - 3.4e-21 75.7 0.0 5.9e-21 75.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class IV F-box-like PF12937.2 KNZ82126.1 - 5e-08 32.5 0.3 1.3e-07 31.2 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ82126.1 - 0.0001 21.8 0.1 0.00024 20.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain YL1 PF05764.8 KNZ82129.1 - 2.7e-28 99.2 17.5 2.7e-28 99.2 12.1 2.1 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 KNZ82129.1 - 2.9e-13 49.0 0.2 5.1e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain L51_S25_CI-B8 PF05047.11 KNZ82130.1 - 4.4e-07 29.5 0.1 8.9e-07 28.5 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Methyltransf_33 PF10017.4 KNZ82130.1 - 0.11 12.3 1.3 0.2 11.5 0.9 1.4 1 1 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DUF915 PF06028.6 KNZ82130.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Pkinase PF00069.20 KNZ82131.1 - 1.6e-12 47.0 0.0 6.6e-06 25.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ82131.1 - 8e-11 41.4 0.0 1.8e-05 23.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.1 KNZ82131.1 - 0.08 12.5 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PhzC-PhzF PF02567.11 KNZ82133.1 - 5.8e-52 176.6 0.0 6.7e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Ppx-GppA PF02541.11 KNZ82133.1 - 0.088 11.9 0.3 0.14 11.3 0.2 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family OTT_1508_deam PF14441.1 KNZ82134.1 - 8.2e-06 25.6 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase DYW_deaminase PF14432.1 KNZ82134.1 - 0.042 13.8 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases DPBB_1 PF03330.13 KNZ82136.1 - 6.2e-12 45.3 0.1 6e-10 38.9 0.0 2.5 2 0 0 2 2 2 2 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KNZ82136.1 - 0.024 14.2 1.1 0.034 13.8 0.1 1.7 2 0 0 2 2 2 0 Barwin family DAO PF01266.19 KNZ82137.1 - 5.3e-21 74.9 0.2 6.2e-21 74.6 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase MutS_V PF00488.16 KNZ82138.1 - 1.1e-68 231.1 0.0 1.9e-68 230.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KNZ82138.1 - 7.4e-31 107.5 1.1 7.4e-31 107.5 0.8 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 KNZ82138.1 - 0.00027 20.9 0.1 0.0041 17.1 0.0 2.8 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KNZ82138.1 - 0.035 14.2 0.0 0.099 12.8 0.0 1.8 1 0 0 1 1 1 0 MutS family domain IV DIOX_N PF14226.1 KNZ82140.1 - 3.2e-16 59.9 0.0 3.5e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Exo_endo_phos PF03372.18 KNZ82142.1 - 0.0012 18.8 0.0 0.0012 18.8 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Herpes_Helicase PF02689.9 KNZ82143.1 - 0.00047 18.0 0.0 0.00052 17.9 0.0 1.0 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 KNZ82144.1 - 2.1e-22 79.5 0.0 2.7e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KNZ82144.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain SAGA-Tad1 PF12767.2 KNZ82145.1 - 0.0036 17.0 5.8 0.0045 16.6 4.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TFIIA PF03153.8 KNZ82146.1 - 0.00095 19.1 14.0 0.0016 18.3 9.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CobT PF06213.7 KNZ82146.1 - 0.17 10.9 15.9 0.26 10.4 11.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Solute_trans_a PF03619.11 KNZ82147.1 - 1.1e-54 185.6 16.0 1.9e-54 184.8 11.1 1.3 1 1 0 1 1 1 1 Organic solute transporter Ostalpha DUF4492 PF14899.1 KNZ82147.1 - 0.036 13.5 0.1 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Glycos_transf_4 PF00953.16 KNZ82147.1 - 3.6 7.3 10.0 49 3.6 6.9 2.9 1 1 0 1 1 1 0 Glycosyl transferase family 4 DUF1275 PF06912.6 KNZ82148.1 - 1.4e-22 79.8 11.0 2e-22 79.4 7.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2231 PF09990.4 KNZ82148.1 - 0.033 14.5 1.0 0.11 12.8 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Med9 PF07544.8 KNZ82149.1 - 0.022 14.4 0.1 0.027 14.1 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 RNA_pol_Rpb1_1 PF04997.7 KNZ82150.1 - 1e-116 389.8 0.0 1.5e-116 389.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KNZ82150.1 - 4e-107 357.5 0.0 5.9e-107 357.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.9 KNZ82150.1 - 4.2e-70 235.3 0.1 1.8e-69 233.2 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_2 PF00623.15 KNZ82150.1 - 2.4e-68 229.3 0.0 4.9e-68 228.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KNZ82150.1 - 2e-51 173.8 0.0 1.1e-50 171.4 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KNZ82150.1 - 1.3e-44 151.1 1.3 3e-44 150.0 0.9 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KNZ82150.1 - 1.7e-35 120.9 0.0 3.6e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 KNZ82150.1 - 0.0005 19.9 204.8 0.079 13.1 3.3 13.7 9 2 5 14 14 14 11 RNA polymerase Rpb1 C-terminal repeat Methyltransf_20 PF12147.3 KNZ82150.1 - 0.096 11.5 0.0 6.3 5.5 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase DDE_Tnp_IS1595 PF12762.2 KNZ82151.1 - 0.04 13.7 0.4 0.088 12.6 0.3 1.5 1 0 0 1 1 1 0 ISXO2-like transposase domain DUF4255 PF14065.1 KNZ82153.1 - 0.024 14.0 0.8 0.037 13.4 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4255) Ribosomal_S30 PF04758.9 KNZ82155.1 - 1.7e-28 98.1 5.8 1.8e-28 98.0 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 IncA PF04156.9 KNZ82156.1 - 0.0059 16.2 5.3 0.0059 16.2 3.7 4.5 3 1 0 3 3 3 2 IncA protein APH PF01636.18 KNZ82157.1 - 2.8e-11 43.6 0.0 3.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KNZ82157.1 - 0.00022 20.6 0.1 0.00037 19.8 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KNZ82157.1 - 0.0043 16.6 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pyr_redox_dim PF02852.17 KNZ82158.1 - 8.2e-45 151.3 1.9 4.3e-43 145.8 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KNZ82158.1 - 1.4e-38 132.7 15.3 2.8e-28 99.1 3.7 4.3 2 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KNZ82158.1 - 1.3e-20 73.5 8.8 5.5e-18 65.1 1.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KNZ82158.1 - 1.9e-11 43.7 0.1 1.9e-11 43.7 0.0 3.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.17 KNZ82158.1 - 3.7e-11 42.5 4.9 3.6e-10 39.2 0.0 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KNZ82158.1 - 8.4e-10 39.0 0.1 1.1e-05 25.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KNZ82158.1 - 4.8e-08 32.9 5.1 0.00018 21.4 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KNZ82158.1 - 1.1e-07 31.0 2.8 1.1e-07 31.0 1.9 3.3 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.9 KNZ82158.1 - 5.3e-07 28.4 12.4 0.00012 20.7 0.6 3.9 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.19 KNZ82158.1 - 5.8e-06 25.4 19.3 0.014 14.2 1.8 3.7 2 2 2 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 KNZ82158.1 - 1.2e-05 24.4 0.3 0.13 11.1 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KNZ82158.1 - 5.3e-05 22.4 3.0 0.00029 20.0 0.0 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KNZ82158.1 - 9.5e-05 21.5 12.1 0.016 14.2 0.6 3.6 3 1 0 3 3 3 3 FAD binding domain AlaDh_PNT_C PF01262.16 KNZ82158.1 - 0.00015 21.3 2.7 0.042 13.4 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain THF_DHG_CYH_C PF02882.14 KNZ82158.1 - 0.0068 15.4 0.1 0.032 13.3 0.1 2.1 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Amino_oxidase PF01593.19 KNZ82158.1 - 0.036 13.1 0.2 0.086 11.9 0.1 1.6 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KNZ82158.1 - 1 8.2 8.4 0.52 9.1 0.4 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 KNZ82158.1 - 3.9 7.7 6.7 13 6.1 0.7 3.5 3 1 0 3 3 3 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 KNZ82158.1 - 9.8 5.7 11.4 0.25 11.0 0.5 2.9 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 KNZ82159.1 - 1.5e-39 135.7 0.0 1.9e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ82159.1 - 7.8e-16 57.9 0.0 1.1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ82159.1 - 0.00015 21.5 0.7 0.00026 20.8 0.5 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KNZ82159.1 - 0.0054 15.7 0.0 0.22 10.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KNZ82159.1 - 0.012 14.7 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IFP_35_N PF07334.8 KNZ82160.1 - 0.021 14.7 3.1 0.024 14.6 1.0 1.9 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF3584 PF12128.3 KNZ82160.1 - 0.022 12.1 0.4 0.027 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mito_fiss_reg PF05308.6 KNZ82160.1 - 0.029 13.7 0.6 0.083 12.2 0.0 1.9 1 1 0 1 1 1 0 Mitochondrial fission regulator Macoilin PF09726.4 KNZ82160.1 - 0.046 12.0 0.0 0.05 11.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein HR1 PF02185.11 KNZ82160.1 - 0.24 11.1 2.5 0.68 9.7 0.9 2.0 2 0 0 2 2 2 0 Hr1 repeat Profilin PF00235.14 KNZ82161.1 - 2.9e-34 117.7 0.0 6.1e-34 116.7 0.0 1.6 1 0 0 1 1 1 1 Profilin zf-TFIIIC PF12660.2 KNZ82161.1 - 1e-19 70.2 1.1 3.1e-19 68.6 0.1 2.1 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.2 KNZ82161.1 - 5.1e-18 65.3 0.2 9.7e-18 64.4 0.2 1.5 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term HAD PF12710.2 KNZ82162.1 - 8.4e-14 52.1 0.0 3.1e-12 47.0 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KNZ82162.1 - 1e-13 51.0 0.0 2.4e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 KNZ82162.1 - 1.1e-13 50.8 0.0 3.7e-13 49.0 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KNZ82162.1 - 3.8e-12 47.0 0.0 7.8e-11 42.7 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KNZ82162.1 - 0.00028 20.5 0.1 0.0078 15.8 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 KNZ82163.1 - 2.6e-24 85.5 0.0 4.3e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KNZ82163.1 - 6.7e-10 38.7 10.8 1.6e-09 37.5 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 KNZ82164.1 - 0.00019 21.0 0.7 0.00019 21.0 0.5 2.3 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KNZ82164.1 - 0.0074 15.8 1.3 34 4.1 0.0 4.6 2 1 2 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KNZ82164.1 - 1 9.1 9.1 0.82 9.4 0.5 4.3 4 2 1 5 5 5 0 Leucine rich repeat LRR_7 PF13504.1 KNZ82164.1 - 2.6 8.6 11.8 54 4.6 0.5 6.6 8 1 1 9 9 9 0 Leucine rich repeat Mito_carr PF00153.22 KNZ82165.1 - 7e-55 182.7 0.4 1.7e-18 66.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_6 PF12697.2 KNZ82166.1 - 5.6e-17 62.3 1.0 1.2e-16 61.2 0.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KNZ82166.1 - 1.1e-15 57.6 0.0 2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KNZ82166.1 - 4.8e-09 36.1 0.4 1.6e-08 34.3 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KNZ82166.1 - 1.6e-07 31.0 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 KNZ82166.1 - 0.0011 18.5 0.2 0.002 17.7 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Ser_hydrolase PF06821.8 KNZ82166.1 - 0.0033 17.0 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Lipase PF00151.14 KNZ82166.1 - 0.0044 16.2 0.0 0.006 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipase Thioesterase PF00975.15 KNZ82166.1 - 0.0046 17.2 0.1 0.023 14.9 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Peptidase_S15 PF02129.13 KNZ82166.1 - 0.0069 15.8 0.0 0.072 12.4 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 KNZ82166.1 - 0.02 14.1 0.1 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2305 PF10230.4 KNZ82166.1 - 0.042 13.2 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 KNZ82166.1 - 0.088 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase DUF818 PF05677.7 KNZ82166.1 - 0.22 10.2 0.0 0.31 9.7 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) RVT_1 PF00078.22 KNZ82167.1 - 0.00031 20.1 0.1 0.00041 19.7 0.1 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HsbA PF12296.3 KNZ82168.1 - 2.5e-09 37.0 2.7 5.3e-09 36.0 1.9 1.6 1 1 0 1 1 1 1 Hydrophobic surface binding protein A tRNA-synt_2d PF01409.15 KNZ82170.1 - 1.4e-29 103.0 0.1 2.3e-26 92.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Pil1 PF13805.1 KNZ82172.1 - 3.9e-12 45.8 0.4 6.6e-12 45.1 0.3 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 DUF4463 PF14703.1 KNZ82172.1 - 0.18 12.3 1.1 7.7 7.1 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) TMF_TATA_bd PF12325.3 KNZ82172.1 - 0.22 11.2 2.1 0.43 10.3 1.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.1 KNZ82172.1 - 0.49 9.3 2.0 0.8 8.6 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Synaptobrevin PF00957.16 KNZ82172.1 - 1.6 8.4 3.3 2.4 7.8 0.2 2.4 2 0 0 2 2 2 0 Synaptobrevin AA_permease PF00324.16 KNZ82173.1 - 8.9e-132 439.7 45.0 1.1e-131 439.5 31.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KNZ82173.1 - 9e-36 123.3 47.4 1.1e-35 122.9 32.9 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.20 KNZ82175.1 - 4.1e-27 95.1 0.5 5.1e-27 94.8 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KNZ82175.1 - 7e-24 84.9 0.1 7.8e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KNZ82175.1 - 4.8e-09 36.1 0.2 7.8e-09 35.4 0.2 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KNZ82175.1 - 0.0091 15.6 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2OG-FeII_Oxy_3 PF13640.1 KNZ82176.1 - 1.2e-12 48.1 0.0 3.3e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KNZ82176.1 - 5.7e-06 25.8 0.1 1e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BPS PF08947.5 KNZ82176.1 - 0.0029 17.2 0.2 0.0066 16.0 0.0 1.6 2 0 0 2 2 2 1 BPS (Between PH and SH2) PhyH PF05721.8 KNZ82176.1 - 0.046 13.7 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy PF03171.15 KNZ82176.1 - 0.066 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF411 PF04214.8 KNZ82177.1 - 0.11 11.9 0.1 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF DUF805 PF05656.9 KNZ82177.1 - 1.1 9.1 7.0 0.14 11.9 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF1455 PF07306.6 KNZ82178.1 - 0.015 15.3 0.3 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) Prefoldin PF02996.12 KNZ82178.1 - 0.059 13.0 0.2 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Prefoldin subunit LBR_tudor PF09465.5 KNZ82178.1 - 0.12 12.0 0.7 0.23 11.1 0.2 1.7 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain LysM PF01476.15 KNZ82179.1 - 6.2e-19 67.6 0.1 1.5e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 LysM domain Ocular_alb PF02101.10 KNZ82179.1 - 0.048 12.2 0.2 0.054 12.0 0.1 1.1 1 0 0 1 1 1 0 Ocular albinism type 1 protein Pkinase PF00069.20 KNZ82181.1 - 8.5e-25 87.3 0.0 1.6e-24 86.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ82181.1 - 4.9e-09 35.6 0.0 3.3e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase p450 PF00067.17 KNZ82183.1 - 1.1e-71 241.7 0.0 1.3e-71 241.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KNZ82186.1 - 9.4e-69 232.1 0.0 1.2e-68 231.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Helitron_like_N PF14214.1 KNZ82187.1 - 2.8e-21 76.0 0.0 3.6e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 KNZ82187.1 - 0.0015 18.0 0.1 0.0018 17.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) Gemini_AL1 PF00799.15 KNZ82187.1 - 0.054 13.3 0.7 0.067 13.0 0.5 1.3 1 1 0 1 1 1 0 Geminivirus Rep catalytic domain PIF1 PF05970.9 KNZ82188.1 - 2.1e-40 138.8 0.1 7.1e-22 77.8 0.0 2.0 1 1 0 2 2 2 2 PIF1-like helicase ResIII PF04851.10 KNZ82188.1 - 0.014 15.2 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KNZ82188.1 - 0.054 13.0 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF779 PF05610.6 KNZ82188.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF779) Viral_helicase1 PF01443.13 KNZ82188.1 - 0.11 11.9 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 KNZ82188.1 - 0.21 10.3 0.6 2.5 6.8 0.1 2.4 1 1 2 3 3 3 0 NB-ARC domain TFIIA PF03153.8 KNZ82190.1 - 9.8e-50 170.5 0.0 2e-32 113.5 0.0 2.6 2 1 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit Gti1_Pac2 PF09729.4 KNZ82190.1 - 4.2e-11 43.0 1.2 1.4e-10 41.3 0.7 1.9 2 0 0 2 2 2 1 Gti1/Pac2 family Gti1_Pac2 PF09729.4 KNZ82191.1 - 2e-27 96.0 0.4 1.3e-22 80.4 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family tRNA-synt_1e PF01406.14 KNZ82192.1 - 1.3e-125 418.4 0.1 1.3e-125 418.4 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KNZ82192.1 - 1.6e-08 33.6 0.3 0.00011 20.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KNZ82192.1 - 3.2e-08 32.0 1.7 0.00028 19.0 0.0 3.3 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 KNZ82192.1 - 1.8e-05 24.8 1.2 5.1e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 DALR domain GLTP PF08718.6 KNZ82194.1 - 2.3e-41 141.2 0.0 2.9e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Rubis-subs-bind PF09273.6 KNZ82195.1 - 3.4e-14 52.8 0.1 6.8e-14 51.8 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 KNZ82195.1 - 4.2e-11 43.4 0.0 1.9e-10 41.3 0.0 2.1 1 1 0 1 1 1 1 SET domain LysM PF01476.15 KNZ82195.1 - 4.8e-06 26.3 0.0 9.6e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 LysM domain CRAL_TRIO PF00650.15 KNZ82196.1 - 9.3e-15 54.4 0.0 1.6e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Metallophos PF00149.23 KNZ82197.1 - 3e-40 137.7 0.8 3.8e-40 137.4 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KNZ82197.1 - 0.0045 16.8 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-C2H2 PF00096.21 KNZ82198.1 - 1.3e-08 34.7 16.0 0.00021 21.4 1.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KNZ82198.1 - 2.1e-08 33.9 12.1 0.00026 21.1 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 KNZ82198.1 - 1.4e-06 27.9 6.6 0.00052 19.7 0.7 2.4 2 0 0 2 2 2 2 BED zinc finger PyrI_C PF02748.10 KNZ82198.1 - 0.0014 18.0 0.3 0.028 13.8 0.1 2.1 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.3 KNZ82198.1 - 0.0059 16.7 6.5 0.14 12.3 0.4 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KNZ82198.1 - 0.0079 16.4 1.4 0.0079 16.4 1.0 2.9 2 1 1 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KNZ82198.1 - 0.042 13.7 6.7 1.9 8.5 0.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KNZ82198.1 - 0.048 13.3 9.6 1.2 8.8 1.8 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 KNZ82198.1 - 0.63 10.0 6.9 2.3 8.2 0.4 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DUF629 PF04780.7 KNZ82198.1 - 0.77 8.2 6.1 4.8 5.5 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 KNZ82198.1 - 3.5 7.7 8.2 0.51 10.4 0.4 2.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-CCCH PF00642.19 KNZ82199.1 - 3.4e-09 36.1 2.7 8.3e-09 34.9 1.9 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 KNZ82199.1 - 3.8e-08 32.8 6.6 6.9e-08 32.0 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KNZ82199.1 - 6.5e-08 32.4 11.2 1.2e-07 31.6 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KNZ82199.1 - 1.3e-06 28.0 9.8 2.1e-06 27.3 6.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KNZ82199.1 - 2.3e-05 24.1 7.1 5.2e-05 23.0 4.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KNZ82199.1 - 4.3e-05 23.2 8.7 7.2e-05 22.5 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KNZ82199.1 - 7.6e-05 22.2 10.5 0.00014 21.4 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KNZ82199.1 - 9.5e-05 22.0 5.6 0.00025 20.6 3.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 KNZ82199.1 - 0.018 14.2 0.6 0.037 13.2 0.4 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger zf-Nse PF11789.3 KNZ82199.1 - 0.02 14.3 3.1 0.04 13.4 2.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 KNZ82199.1 - 2.3 8.3 7.0 8 6.6 4.9 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RanBP PF00641.13 KNZ82199.1 - 8.7 5.5 8.8 0.15 11.1 1.2 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others ATP-synt_G PF04718.10 KNZ82200.1 - 1.1e-08 35.6 0.1 3.3e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit bZIP_2 PF07716.10 KNZ82201.1 - 2e-09 37.0 14.4 2e-09 37.0 10.0 2.0 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 KNZ82201.1 - 0.00032 20.5 14.9 0.00032 20.5 10.3 2.6 2 1 0 2 2 2 1 bZIP transcription factor PAT1 PF09770.4 KNZ82201.1 - 0.00086 17.6 6.1 0.0011 17.3 4.2 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 CASP_C PF08172.7 KNZ82201.1 - 0.008 15.2 2.3 0.014 14.4 1.6 1.3 1 0 0 1 1 1 1 CASP C terminal XhlA PF10779.4 KNZ82201.1 - 0.0083 16.0 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 Haemolysin XhlA bZIP_Maf PF03131.12 KNZ82201.1 - 0.031 14.5 5.2 0.031 14.5 3.6 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor TSC22 PF01166.13 KNZ82201.1 - 0.071 13.0 0.5 0.17 11.8 0.3 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family CUE PF02845.11 KNZ82202.1 - 0.00011 21.6 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain ATP-synt_C PF00137.16 KNZ82203.1 - 3.8e-27 93.9 30.1 1.7e-16 59.8 5.4 2.7 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.1 KNZ82203.1 - 0.016 15.4 0.9 0.63 10.3 0.2 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 Oxidored_q2 PF00420.19 KNZ82203.1 - 2.8 7.5 8.3 2 8.0 2.4 2.8 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Arf PF00025.16 KNZ82204.1 - 4.4e-39 133.5 0.0 2e-38 131.3 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KNZ82204.1 - 2.1e-12 46.4 0.0 1.8e-07 30.1 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KNZ82204.1 - 2.1e-08 33.7 0.0 3.2e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ82204.1 - 3.3e-08 34.0 0.0 4.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KNZ82204.1 - 2.2e-06 27.6 0.0 3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KNZ82204.1 - 3.6e-06 26.2 0.0 4.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KNZ82204.1 - 4.4e-06 26.0 0.0 6.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KNZ82204.1 - 0.00011 21.6 0.0 0.01 15.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.14 KNZ82204.1 - 0.0011 18.3 0.0 0.083 12.3 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 KNZ82204.1 - 0.0034 17.6 0.3 0.0066 16.7 0.0 1.5 2 0 0 2 2 1 1 ABC transporter AAA_22 PF13401.1 KNZ82204.1 - 0.0038 17.3 0.0 0.0078 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KNZ82204.1 - 0.0065 16.0 0.2 0.012 15.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KNZ82204.1 - 0.0072 16.3 0.1 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Thymidylate_kin PF02223.12 KNZ82204.1 - 0.015 14.6 0.1 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_17 PF13207.1 KNZ82204.1 - 0.023 15.5 1.3 0.041 14.6 0.9 1.8 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KNZ82204.1 - 0.024 14.0 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 KNZ82204.1 - 0.025 14.8 0.5 0.03 14.6 0.3 1.4 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 KNZ82204.1 - 0.034 13.1 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.1 KNZ82204.1 - 0.035 13.6 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.1 KNZ82204.1 - 0.044 12.8 0.1 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 KNZ82204.1 - 0.044 13.4 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 KNZ82204.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 KNZ82204.1 - 0.066 13.1 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KNZ82204.1 - 0.071 12.9 0.0 0.23 11.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KNZ82204.1 - 0.074 12.7 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 KNZ82204.1 - 0.074 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 KNZ82204.1 - 0.079 12.0 0.3 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 KNZ82204.1 - 0.14 12.5 0.6 0.23 11.7 0.4 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KNZ82204.1 - 0.15 11.7 0.1 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B adh_short PF00106.20 KNZ82205.1 - 1.2e-24 87.1 0.5 1.8e-24 86.5 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KNZ82205.1 - 4.3e-08 33.0 0.8 0.00025 20.7 0.1 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KNZ82205.1 - 6.2e-06 26.1 0.2 1.2e-05 25.1 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Septin PF00735.13 KNZ82206.1 - 2e-105 351.8 0.0 2e-105 351.8 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KNZ82206.1 - 8.1e-06 25.7 0.0 2.3e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KNZ82206.1 - 2.1e-05 24.4 3.5 0.039 13.7 0.0 3.0 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 KNZ82206.1 - 0.00049 19.3 0.1 0.0012 18.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KNZ82206.1 - 0.0014 19.4 1.0 0.018 15.8 0.0 2.7 1 1 1 2 2 2 1 AAA domain AIG1 PF04548.11 KNZ82206.1 - 0.0021 17.2 0.0 0.0039 16.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_10 PF12846.2 KNZ82206.1 - 0.0043 16.5 0.0 0.014 14.8 0.0 1.8 2 1 0 2 2 2 1 AAA-like domain FtsK_SpoIIIE PF01580.13 KNZ82206.1 - 0.02 14.3 0.0 0.053 12.9 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.9 KNZ82206.1 - 0.022 14.4 0.0 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KNZ82206.1 - 0.033 14.6 0.0 0.085 13.3 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 KNZ82206.1 - 0.051 13.8 0.2 0.22 11.8 0.0 2.1 2 1 0 2 2 2 0 ABC transporter Pox_A32 PF04665.7 KNZ82206.1 - 0.061 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein PqqD PF05402.7 KNZ82206.1 - 0.067 13.2 0.1 0.21 11.6 0.1 1.8 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) ATP_bind_1 PF03029.12 KNZ82206.1 - 0.087 12.3 0.1 0.9 9.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 KNZ82206.1 - 0.093 12.8 0.0 0.4 10.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KNZ82206.1 - 0.11 12.0 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 KNZ82206.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Atg14 PF10186.4 KNZ82206.1 - 0.56 9.0 6.6 0.83 8.5 4.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF87 PF01935.12 KNZ82206.1 - 2.3 7.9 5.0 12 5.6 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function DUF87 Voltage_CLC PF00654.15 KNZ82207.1 - 7.6e-86 288.3 38.5 7.6e-86 288.3 26.7 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KNZ82207.1 - 7.1e-10 38.5 1.8 1.5e-05 24.7 0.1 2.5 2 0 0 2 2 2 2 CBS domain DUF663 PF04950.7 KNZ82208.1 - 6.9e-80 268.1 0.0 1.3e-79 267.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KNZ82208.1 - 3.6e-19 68.0 0.0 9.8e-19 66.6 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain HemY_N PF07219.8 KNZ82208.1 - 4.6 6.8 5.0 11 5.6 3.5 1.6 1 0 0 1 1 1 0 HemY protein N-terminus SWIRM PF04433.12 KNZ82209.1 - 6.9e-16 58.1 0.0 1.6e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KNZ82209.1 - 1.5e-10 40.9 0.3 3.4e-10 39.8 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KNZ82209.1 - 0.00041 20.3 0.0 0.0009 19.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 KNZ82209.1 - 0.13 11.8 11.1 0.29 10.7 7.7 1.6 1 1 0 1 1 1 0 Zinc finger, ZZ type Methyltransf_10 PF05971.7 KNZ82212.1 - 2.9e-50 171.0 0.0 2.2e-49 168.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 KNZ82212.1 - 0.00087 19.3 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KNZ82212.1 - 0.013 16.0 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KNZ82212.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Helitron_like_N PF14214.1 KNZ82214.1 - 2.9e-57 193.3 0.3 3.6e-57 193.0 0.2 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus MH1 PF03165.11 KNZ82214.1 - 0.0019 18.1 0.4 0.0095 15.9 0.0 2.2 2 2 0 2 2 2 1 MH1 domain Phage_GPA PF05840.8 KNZ82214.1 - 0.088 11.5 0.2 0.12 11.0 0.2 1.2 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Glyco_hydro_47 PF01532.15 KNZ82220.1 - 1.7e-129 432.4 0.0 1.9e-129 432.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ribosomal_S4 PF00163.14 KNZ82221.1 - 2.5e-27 95.0 1.1 4.5e-27 94.2 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KNZ82221.1 - 3.5e-12 45.5 0.8 3.5e-12 45.5 0.5 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 KNZ82222.1 - 4e-36 122.7 3.3 6.1e-36 122.1 2.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e Surface_Ag_2 PF01617.12 KNZ82222.1 - 0.086 12.0 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Surface antigen HlyD PF00529.15 KNZ82223.1 - 0.097 11.9 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein TauD PF02668.11 KNZ82225.1 - 7.8e-48 163.3 0.9 1.5e-47 162.4 0.6 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PGI PF00342.14 KNZ82226.1 - 3.2e-213 708.5 0.6 4.3e-213 708.1 0.4 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase DTHCT PF08070.6 KNZ82227.1 - 2.8 8.6 12.3 0.33 11.6 1.7 2.6 2 0 0 2 2 2 0 DTHCT (NUC029) region zf-CCHC PF00098.18 KNZ82230.1 - 0.019 14.8 0.6 0.037 13.9 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle MFS_1 PF07690.11 KNZ82231.1 - 9e-31 106.8 75.7 3.1e-21 75.4 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KNZ82231.1 - 0.045 13.5 7.1 0.19 11.5 1.1 2.8 3 0 0 3 3 3 0 MFS_1 like family Cu_amine_oxid PF01179.15 KNZ82232.1 - 1.1e-154 515.1 0.0 1.3e-154 514.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KNZ82232.1 - 0.00031 20.7 0.1 0.00075 19.5 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KNZ82232.1 - 0.00044 20.2 0.0 0.00098 19.1 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxid PF01179.15 KNZ82233.1 - 1.1e-155 518.4 0.0 1.4e-155 518.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KNZ82233.1 - 4.7e-17 61.8 0.0 8.9e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KNZ82233.1 - 2.5e-06 27.4 0.1 6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF2794 PF10984.3 KNZ82235.1 - 0.068 13.0 0.0 0.08 12.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2794) UPF0449 PF15136.1 KNZ82235.1 - 0.11 12.7 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Chitin_synth_2 PF03142.10 KNZ82238.1 - 9.7e-281 931.7 0.0 1.4e-280 931.1 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KNZ82238.1 - 3.5e-16 59.5 0.6 3.5e-16 59.5 0.4 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KNZ82238.1 - 9.7e-13 48.4 0.0 6.2e-12 45.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KNZ82238.1 - 5.1e-05 22.6 0.1 0.0027 17.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KNZ82238.1 - 0.018 14.7 0.0 0.096 12.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 Sec61_beta PF03911.11 KNZ82238.1 - 2.6 7.9 5.5 8 6.3 3.8 1.9 1 0 0 1 1 1 0 Sec61beta family Sugar_tr PF00083.19 KNZ82239.1 - 7.3e-27 94.0 36.4 1.2e-19 70.2 5.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KNZ82239.1 - 1.1e-20 73.7 67.7 6.9e-18 64.4 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KNZ82239.1 - 0.00013 20.5 1.9 0.00013 20.5 1.3 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein CRAL_TRIO PF00650.15 KNZ82241.1 - 1.2e-33 115.8 0.0 2.2e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KNZ82241.1 - 6e-06 26.2 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Nop10p PF04135.7 KNZ82242.1 - 1.2e-20 72.9 0.1 1.5e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Thioredoxin PF00085.15 KNZ82243.1 - 6.3e-25 86.8 0.0 7.4e-25 86.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KNZ82243.1 - 8.3e-08 32.4 0.1 5.3e-07 29.8 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KNZ82243.1 - 3e-06 27.2 0.0 0.00018 21.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 KNZ82243.1 - 3.1e-05 23.5 0.1 0.0073 15.8 0.0 2.1 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 KNZ82243.1 - 0.00041 20.0 0.0 0.00068 19.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KNZ82243.1 - 0.0006 19.7 0.0 0.0008 19.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.19 KNZ82243.1 - 0.004 17.1 0.0 0.0084 16.0 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 KNZ82243.1 - 0.0088 15.6 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin KaiB PF07689.7 KNZ82243.1 - 0.05 13.0 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 KaiB domain TPR_9 PF13371.1 KNZ82244.1 - 0.0019 18.0 0.5 0.0083 15.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ82244.1 - 0.099 12.3 0.8 1.2 8.7 0.0 2.8 3 0 0 3 3 3 0 TPR repeat RdRP PF05183.7 KNZ82245.1 - 4.2e-119 398.8 0.0 6e-119 398.3 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Ribosomal_L32p PF01783.18 KNZ82245.1 - 0.022 14.9 0.2 0.071 13.2 0.1 1.9 1 0 0 1 1 1 0 Ribosomal L32p protein family SMC_N PF02463.14 KNZ82246.1 - 2e-68 229.9 0.0 3.4e-68 229.1 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KNZ82246.1 - 6.4e-25 87.4 0.0 1.7e-24 86.1 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KNZ82246.1 - 2.8e-13 50.4 2.6 3e-06 27.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KNZ82246.1 - 3.9e-05 23.0 0.0 8.7e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KNZ82246.1 - 0.00098 18.3 1.9 0.00098 18.3 1.3 3.6 2 2 2 4 4 4 1 Reovirus sigma C capsid protein ABC_tran PF00005.22 KNZ82246.1 - 0.84 9.9 0.0 0.84 9.9 0.0 5.7 4 2 0 4 4 4 0 ABC transporter WD40 PF00400.27 KNZ82248.1 - 2e-184 591.7 60.0 6.6e-15 54.3 0.3 15.5 15 0 0 15 15 15 15 WD domain, G-beta repeat PD40 PF07676.7 KNZ82248.1 - 3.6e-18 64.8 26.3 1.4 8.6 0.1 13.7 14 0 0 14 14 14 6 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 KNZ82248.1 - 3e-15 55.3 14.9 0.00038 18.8 0.2 5.9 2 2 3 6 6 6 5 Cytochrome D1 heme domain NACHT PF05729.7 KNZ82248.1 - 3.7e-11 42.9 0.0 7.2e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF1258 PF06869.7 KNZ82248.1 - 1.2e-05 24.5 5.9 3.3 6.7 0.0 7.8 3 2 8 11 11 11 1 Protein of unknown function (DUF1258) HARP PF07443.8 KNZ82248.1 - 1.3e-05 24.4 0.0 26 4.2 0.0 7.2 8 0 0 8 8 8 0 HepA-related protein (HARP) DUF4221 PF13970.1 KNZ82248.1 - 1.4e-05 24.6 3.3 0.63 9.2 0.0 5.9 2 2 4 7 7 7 1 Domain of unknown function (DUF4221) AAA_16 PF13191.1 KNZ82248.1 - 3.2e-05 23.9 0.0 0.00014 21.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 KNZ82248.1 - 0.0031 17.2 0.0 0.0082 15.8 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 KNZ82248.1 - 0.0043 17.1 0.1 0.034 14.2 0.0 2.3 2 1 1 3 3 3 1 AAA domain ABC_tran PF00005.22 KNZ82248.1 - 0.012 15.8 0.0 0.051 13.8 0.0 2.0 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 KNZ82248.1 - 0.018 13.9 0.0 0.044 12.6 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain DUF2233 PF09992.4 KNZ82248.1 - 0.02 14.8 3.1 38 4.2 0.1 5.5 1 1 4 5 5 5 0 Predicted periplasmic protein (DUF2233) AAA_29 PF13555.1 KNZ82248.1 - 0.023 14.2 0.0 0.09 12.3 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KNZ82248.1 - 0.025 13.6 0.0 0.07 12.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 KNZ82248.1 - 0.033 13.9 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 KNZ82248.1 - 0.035 14.2 0.0 0.12 12.5 0.0 2.0 1 0 0 1 1 1 0 RNA helicase PhoU_div PF01865.11 KNZ82248.1 - 0.075 12.2 0.1 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF47 AAA_14 PF13173.1 KNZ82248.1 - 0.088 12.7 0.0 1.7 8.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 KNZ82248.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Proteasome_A_N PF10584.4 KNZ82248.1 - 0.31 10.4 28.3 1e+02 2.3 0.1 11.6 12 0 0 12 12 12 0 Proteasome subunit A N-terminal signature Asp_protease_2 PF13650.1 KNZ82251.1 - 1.6e-05 25.3 0.0 4.5e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KNZ82251.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.18 KNZ82252.1 - 0.095 12.6 0.5 0.17 11.8 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle LysM PF01476.15 KNZ82254.1 - 4.9e-11 42.3 0.0 7.5e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 LysM domain Ank_2 PF12796.2 KNZ82255.1 - 4.9e-09 36.3 0.1 4.6e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KNZ82255.1 - 1e-08 35.4 0.0 0.0036 17.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KNZ82255.1 - 5.4e-08 32.3 0.1 0.0053 16.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 KNZ82255.1 - 1.3e-07 31.0 0.0 7.3e-05 22.3 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 KNZ82255.1 - 0.00059 19.9 0.1 0.034 14.3 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) PilM_2 PF11104.3 KNZ82255.1 - 0.14 11.0 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; HhH-GPD PF00730.20 KNZ82256.1 - 1.5e-16 60.6 0.0 3.1e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 KNZ82256.1 - 4.9e-11 42.0 0.0 3.5e-10 39.3 0.0 2.3 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.18 KNZ82256.1 - 0.0084 15.7 0.3 0.045 13.4 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KNZ82256.1 - 0.028 14.6 0.1 0.48 10.6 0.0 2.7 2 1 0 2 2 2 0 Helix-hairpin-helix domain DUF4636 PF15468.1 KNZ82256.1 - 0.18 11.2 2.8 0.29 10.5 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) EndIII_4Fe-2S PF10576.4 KNZ82256.1 - 2.7 8.2 8.6 5.7 7.2 5.9 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Gti1_Pac2 PF09729.4 KNZ82259.1 - 1.3e-19 70.7 0.6 7.5e-10 38.9 0.0 3.4 2 1 1 3 3 3 3 Gti1/Pac2 family Chromo PF00385.19 KNZ82260.1 - 4.8e-05 22.9 0.1 6.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KNZ82260.1 - 0.00025 20.6 0.0 0.0018 17.9 0.0 2.0 1 1 1 2 2 2 1 RNA binding activity-knot of a chromodomain gag-asp_proteas PF13975.1 KNZ82263.1 - 7.4e-05 22.4 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KNZ82263.1 - 0.00057 20.3 0.0 0.0056 17.1 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.6 KNZ82263.1 - 0.062 13.2 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease Sec5 PF15469.1 KNZ82265.1 - 7.7e-56 188.6 0.3 1.6e-54 184.4 0.0 3.1 3 1 1 4 4 4 1 Exocyst complex component Sec5 DUF155 PF02582.9 KNZ82266.1 - 2.8e-56 190.1 0.2 4.7e-56 189.4 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DDE_3 PF13358.1 KNZ82267.1 - 2.3e-06 27.4 0.7 1.2e-05 25.0 0.5 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF724 PF05266.9 KNZ82267.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) AMP-binding PF00501.23 KNZ82268.1 - 1e-74 251.4 0.0 2.5e-74 250.1 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KNZ82268.1 - 1.7e-09 38.5 0.0 3.9e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.1 KNZ82268.1 - 0.05 13.6 0.1 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain DUF1498 PF07385.7 KNZ82268.1 - 0.16 11.1 0.2 13 4.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1498) Mito_carr PF00153.22 KNZ82269.1 - 8.7e-52 172.8 0.8 3e-17 62.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNase_H PF00075.19 KNZ82270.1 - 3.7e-13 49.9 0.2 3.5e-12 46.7 0.1 2.1 1 1 0 1 1 1 1 RNase H MORN PF02493.15 KNZ82270.1 - 0.061 13.0 1.1 0.17 11.6 0.8 1.9 1 0 0 1 1 1 0 MORN repeat His_Phos_2 PF00328.17 KNZ82271.1 - 2.7e-29 102.5 0.0 3.7e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ADH_N PF08240.7 KNZ82272.1 - 1e-32 112.1 3.4 1.8e-32 111.3 2.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KNZ82272.1 - 1.2e-14 54.0 0.0 1.7e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KNZ82272.1 - 0.00054 20.8 0.0 0.0011 19.8 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KNZ82272.1 - 0.00063 18.9 1.0 0.0009 18.3 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain DUF2338 PF10100.4 KNZ82272.1 - 0.0067 14.8 0.0 0.0099 14.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2338) Saccharop_dh PF03435.13 KNZ82272.1 - 0.054 12.4 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 KNZ82272.1 - 0.055 13.7 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 KNZ82272.1 - 0.074 13.1 0.1 0.16 12.0 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YrhK PF14145.1 KNZ82273.1 - 0.0059 16.2 18.4 0.59 9.8 3.7 4.5 3 2 0 3 3 3 3 YrhK-like protein DUF2631 PF10939.3 KNZ82273.1 - 0.029 14.2 0.8 0.1 12.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) AAA_12 PF13087.1 KNZ82274.1 - 1.2e-44 152.1 0.0 1.8e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KNZ82274.1 - 1.9e-30 106.1 0.0 4.1e-14 52.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 KNZ82274.1 - 6.4e-11 42.2 0.0 2.1e-09 37.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KNZ82274.1 - 9e-10 38.1 0.0 1.5e-08 34.2 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 KNZ82274.1 - 8.6e-05 21.9 0.0 0.04 13.2 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain zf-met PF12874.2 KNZ82274.1 - 0.00015 21.8 2.4 0.00015 21.8 1.7 3.0 3 0 0 3 3 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KNZ82274.1 - 0.0016 18.5 0.7 0.0016 18.5 0.5 3.8 4 1 0 4 4 3 1 Zinc-finger double-stranded RNA-binding PhoH PF02562.11 KNZ82274.1 - 0.0024 17.1 0.0 0.65 9.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein UvrD_C PF13361.1 KNZ82274.1 - 0.0029 17.1 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KNZ82274.1 - 0.003 17.0 0.0 2.7 7.4 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KNZ82274.1 - 0.014 15.5 0.0 0.043 13.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA PF00004.24 KNZ82274.1 - 0.02 15.0 0.0 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KNZ82274.1 - 0.061 12.7 0.0 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain Helicase_RecD PF05127.9 KNZ82274.1 - 0.13 11.9 0.0 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 Helicase AAA_16 PF13191.1 KNZ82274.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 KNZ82274.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) zf-C2H2 PF00096.21 KNZ82274.1 - 2.1 8.8 7.6 0.13 12.6 1.0 2.4 2 0 0 2 2 1 0 Zinc finger, C2H2 type DUF3505 PF12013.3 KNZ82274.1 - 3 8.1 9.8 5.8 7.1 0.4 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3505) zf-C2H2_2 PF12756.2 KNZ82274.1 - 4.1 7.5 11.5 0.23 11.5 1.0 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) RVP_2 PF08284.6 KNZ82275.1 - 0.073 13.0 0.0 0.08 12.8 0.0 1.0 1 0 0 1 1 1 0 Retroviral aspartyl protease G-alpha PF00503.15 KNZ82276.1 - 3e-150 500.2 0.0 3.8e-150 499.9 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KNZ82276.1 - 3.8e-10 39.2 0.1 1.1e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 KNZ82276.1 - 0.0028 17.1 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KNZ82276.1 - 0.088 13.1 0.0 0.17 12.2 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AA_kinase PF00696.23 KNZ82277.1 - 1e-37 130.0 0.0 1.6e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 KNZ82277.1 - 1.2e-12 46.9 0.3 6.1e-07 28.7 0.0 2.9 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 KNZ82277.1 - 4.2e-12 45.4 1.2 1.1e-08 34.4 0.1 2.9 3 0 0 3 3 3 2 ACT domain ChAPs PF09295.5 KNZ82278.1 - 6.8e-147 489.3 0.0 3e-145 483.9 0.0 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_16 PF13432.1 KNZ82278.1 - 1.3e-06 28.9 1.2 0.091 13.4 0.1 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KNZ82278.1 - 4.9e-06 26.7 6.7 2.5e-05 24.5 0.1 4.0 5 0 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KNZ82278.1 - 1.8e-05 24.7 5.0 0.04 14.0 0.1 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KNZ82278.1 - 2.2e-05 23.9 0.7 0.32 10.8 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KNZ82278.1 - 4.7e-05 22.9 5.8 0.041 13.5 0.1 3.8 3 0 0 3 3 3 2 TPR repeat TPR_15 PF13429.1 KNZ82278.1 - 0.00044 19.4 5.5 0.11 11.5 1.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KNZ82278.1 - 0.00055 19.8 5.1 9.3 6.2 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KNZ82278.1 - 0.00069 20.0 6.5 0.45 11.2 0.2 6.2 5 3 2 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 KNZ82278.1 - 0.0029 17.3 11.4 3.2 7.9 0.3 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KNZ82278.1 - 0.032 14.6 8.0 32 5.2 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 KNZ82278.1 - 0.11 12.3 3.3 1.7 8.6 0.0 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2046 PF09755.4 KNZ82279.1 - 9.7e-14 50.9 4.2 3.1e-12 46.0 2.4 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) DUF2353 PF09789.4 KNZ82279.1 - 0.036 13.3 2.2 0.053 12.7 1.5 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Atg14 PF10186.4 KNZ82279.1 - 0.055 12.4 2.4 0.27 10.1 1.7 2.0 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KNZ82279.1 - 8.4 5.9 7.6 8.5 5.9 2.1 2.2 2 0 0 2 2 2 0 IncA protein HSP20 PF00011.16 KNZ82280.1 - 2.2e-11 43.4 0.0 1.9e-10 40.5 0.0 2.2 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Mg_trans_NIPA PF05653.9 KNZ82281.1 - 8.3e-105 350.0 14.1 1e-104 349.7 9.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KNZ82281.1 - 1.2e-05 25.4 5.3 1.2e-05 25.4 3.6 3.4 2 2 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 KNZ82281.1 - 0.0054 16.7 5.8 0.0054 16.7 4.0 3.4 3 1 0 3 3 3 1 EamA-like transporter family PrgI PF12666.2 KNZ82281.1 - 1.2 9.3 0.0 1.2 9.3 0.0 3.4 2 1 4 6 6 6 0 PrgI family protein YSIRK_signal PF04650.12 KNZ82281.1 - 2.7 7.6 6.2 13 5.4 0.4 2.8 2 0 0 2 2 2 0 YSIRK type signal peptide Peptidase_M24 PF00557.19 KNZ82282.1 - 3.6e-37 127.9 0.0 6.3e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KNZ82282.1 - 2.1e-23 83.2 0.0 3.5e-20 72.8 0.0 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Exo_endo_phos PF03372.18 KNZ82283.1 - 6.4e-13 49.2 0.1 8.2e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KNZ82283.1 - 0.046 13.3 0.0 7.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase UBN2_2 PF14227.1 KNZ82284.1 - 5e-08 32.5 0.0 6.9e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ82284.1 - 0.00024 20.8 0.1 0.00034 20.3 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KNZ82284.1 - 0.0013 18.3 0.1 0.0018 17.8 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.10 KNZ82284.1 - 0.025 14.3 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) F-box-like PF12937.2 KNZ82288.1 - 0.026 14.2 1.3 0.28 10.9 0.9 2.7 1 1 0 1 1 1 0 F-box-like PIF1 PF05970.9 KNZ82291.1 - 2.4e-32 112.3 0.1 2.7e-32 112.1 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase Chitin_synth_2 PF03142.10 KNZ82292.1 - 1.8e-184 614.0 0.5 4.7e-183 609.3 0.1 2.5 1 1 1 2 2 2 1 Chitin synthase Myosin_head PF00063.16 KNZ82292.1 - 3.5e-157 524.4 0.0 4.6e-157 524.0 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 KNZ82292.1 - 9e-18 63.7 1.9 3.9e-17 61.7 1.0 2.2 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 KNZ82292.1 - 1.1e-12 47.5 0.0 1.6e-05 24.5 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 KNZ82292.1 - 5.6e-12 45.9 0.0 2.5e-08 34.0 0.0 2.8 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KNZ82292.1 - 1.1e-11 44.8 0.3 1.1e-11 44.8 0.2 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KNZ82292.1 - 0.011 15.4 0.0 0.97 9.0 0.0 2.9 3 0 0 3 3 3 0 Glycosyl transferase family 2 YwiC PF14256.1 KNZ82292.1 - 0.061 13.4 1.1 0.14 12.2 0.8 1.5 1 0 0 1 1 1 0 YwiC-like protein UBN2_2 PF14227.1 KNZ82293.1 - 2.5e-07 30.2 0.2 4.3e-07 29.5 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KNZ82293.1 - 4.4e-05 23.2 0.3 8.2e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type WD40 PF00400.27 KNZ82295.1 - 7.3e-09 35.1 5.6 0.09 12.7 0.0 6.4 6 1 0 6 6 6 2 WD domain, G-beta repeat Nop14 PF04147.7 KNZ82295.1 - 0.089 10.7 6.3 0.13 10.1 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family Mid1 PF12929.2 KNZ82296.1 - 8.1e-71 238.9 0.0 1.3e-70 238.3 0.0 1.3 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KNZ82296.1 - 0.19 12.1 2.7 3.4 8.0 0.2 2.3 2 0 0 2 2 2 0 Fz domain DUF92 PF01940.11 KNZ82297.1 - 2.2e-42 144.7 12.1 4.1e-26 91.5 0.5 2.1 1 1 1 2 2 2 2 Integral membrane protein DUF92 DUF3218 PF11508.3 KNZ82297.1 - 0.056 12.9 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3218) Glycogen_syn PF05693.8 KNZ82298.1 - 0 1080.3 0.0 0 1080.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KNZ82298.1 - 4.3e-09 36.0 0.0 4.6e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KNZ82298.1 - 1.6e-07 31.1 1.0 4.6e-07 29.5 0.1 2.1 2 0 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 KNZ82298.1 - 5.3e-07 29.9 1.0 3.2e-06 27.3 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Kdo PF06293.9 KNZ82300.1 - 2e-05 23.7 0.1 4.2e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KNZ82300.1 - 2e-05 23.8 0.1 4.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KNZ82300.1 - 0.00018 21.3 0.3 0.00049 19.8 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 KNZ82300.1 - 0.0067 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.15 KNZ82300.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase SAGA-Tad1 PF12767.2 KNZ82301.1 - 0.051 13.2 8.2 0.083 12.5 5.7 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit ABC1 PF03109.11 KNZ82302.1 - 4.5e-26 91.1 0.0 9.9e-26 90.0 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 KNZ82302.1 - 0.0019 17.9 0.0 0.016 14.9 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 KNZ82303.1 - 1.7e-35 122.4 0.0 2.7e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ82303.1 - 1.7e-10 40.4 0.0 1.9e-07 30.4 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KNZ82303.1 - 0.05 12.6 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF21 PF01595.15 KNZ82305.1 - 5.8e-23 81.1 0.8 9.3e-23 80.4 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KNZ82305.1 - 1.5e-06 27.9 4.5 0.0018 18.0 0.1 3.8 4 0 0 4 4 4 2 CBS domain DUF1840 PF08895.6 KNZ82305.1 - 0.13 12.3 0.0 0.52 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Saccharop_dh PF03435.13 KNZ82307.1 - 2e-75 254.2 0.0 2.6e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_N PF05222.10 KNZ82307.1 - 9.9e-15 54.7 0.0 5e-14 52.4 0.0 2.2 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KNZ82307.1 - 2e-08 33.9 0.0 5e-07 29.4 0.0 2.6 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 KNZ82307.1 - 2.9e-06 27.4 0.0 6.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 KNZ82307.1 - 0.088 13.3 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Gpi1 PF05024.10 KNZ82308.1 - 3.5e-45 154.0 7.1 3.5e-45 154.0 4.9 1.6 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) MMPL PF03176.10 KNZ82308.1 - 0.094 11.4 0.3 0.17 10.5 0.2 1.3 1 0 0 1 1 1 0 MMPL family Ras PF00071.17 KNZ82309.1 - 1.1e-53 180.9 0.0 1.3e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KNZ82309.1 - 2.3e-16 60.3 0.0 3.2e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KNZ82309.1 - 1.3e-06 27.7 0.0 3.1e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KNZ82309.1 - 0.0073 15.4 0.0 0.0089 15.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KNZ82309.1 - 0.13 12.3 0.0 1.3 9.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain GH114_assoc PF14741.1 KNZ82309.1 - 0.14 11.8 0.0 1.4 8.6 0.0 2.0 1 1 1 2 2 2 0 N-terminal glycosyl-hydrolase-114-associated domain Cellulase PF00150.13 KNZ82311.1 - 5.1e-29 101.3 0.8 8.8e-29 100.5 0.6 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CAF-1_p150 PF11600.3 KNZ82313.1 - 0.085 12.2 24.4 0.23 10.7 16.9 1.8 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 KNZ82313.1 - 3.7 5.8 28.6 7.6 4.8 14.9 2.9 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 F-box-like PF12937.2 KNZ82315.1 - 0.00013 21.6 0.6 0.00049 19.7 0.4 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KNZ82315.1 - 0.00021 20.8 0.1 0.0036 16.9 0.0 2.9 2 1 0 2 2 2 1 F-box domain DUF3678 PF12435.3 KNZ82315.1 - 0.046 13.2 1.9 0.11 12.0 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) F-box-like PF12937.2 KNZ82316.1 - 1.7e-06 27.6 1.2 5e-06 26.1 0.8 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KNZ82316.1 - 0.00078 19.1 2.2 0.0022 17.6 0.1 2.5 2 0 0 2 2 2 1 F-box-like domain F-box PF00646.28 KNZ82316.1 - 0.003 17.1 3.0 0.057 13.0 2.1 2.4 1 1 0 1 1 1 1 F-box domain IBR PF01485.16 KNZ82318.1 - 0.055 13.3 10.9 1.7 8.5 4.8 2.5 2 1 0 2 2 2 0 IBR domain FYVE_2 PF02318.11 KNZ82318.1 - 0.33 10.8 7.6 1 9.2 3.4 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Siva PF05458.7 KNZ82318.1 - 3.8 7.0 16.4 0.7 9.4 8.1 1.9 2 0 0 2 2 2 0 Cd27 binding protein (Siva) FYVE PF01363.16 KNZ82318.1 - 5.3 7.0 15.4 2.7 7.9 0.1 2.5 2 1 0 2 2 2 0 FYVE zinc finger Spherulin4 PF12138.3 KNZ82319.1 - 1.9e-32 112.7 0.0 2.3e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 p450 PF00067.17 KNZ82320.1 - 6e-55 186.6 0.0 1.2e-54 185.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 ATG16 PF08614.6 KNZ82321.1 - 3.9 7.2 8.2 0.33 10.7 1.9 1.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Kdo PF06293.9 KNZ82322.1 - 9.6e-06 24.8 0.0 0.00015 20.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 KNZ82322.1 - 2.9e-05 23.3 0.1 5.1e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.20 KNZ82322.1 - 0.00036 19.7 0.0 0.00046 19.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KNZ82322.1 - 0.0024 17.6 0.0 0.022 14.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KNZ82322.1 - 0.016 14.5 0.0 0.031 13.6 0.0 1.4 1 1 0 1 1 1 0 RIO1 family TP_methylase PF00590.15 KNZ82322.1 - 0.059 13.0 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Pkinase PF00069.20 KNZ82323.1 - 9.1e-13 47.9 0.0 6.2e-11 41.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ82323.1 - 6.5e-06 25.4 0.0 0.00014 21.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 KNZ82323.1 - 0.013 14.3 0.1 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HMG_box PF00505.14 KNZ82324.1 - 0.0065 16.7 3.9 0.011 15.9 2.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box ChlamPMP_M PF07548.6 KNZ82324.1 - 0.085 12.5 0.1 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein middle domain Ion_trans PF00520.26 KNZ82325.1 - 1.5e-100 334.4 92.2 1.5e-32 112.5 5.6 5.2 5 0 0 5 5 5 4 Ion transport protein Cas_Csd1 PF09709.5 KNZ82325.1 - 0.16 10.2 0.0 3.1 5.9 0.0 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csd1) PCI PF01399.22 KNZ82326.1 - 1.8e-08 34.6 1.5 7.4e-05 23.0 0.0 4.1 4 1 1 5 5 5 2 PCI domain PIF1 PF05970.9 KNZ82329.1 - 2.2e-105 352.6 0.0 2.9e-105 352.1 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 KNZ82329.1 - 1.1e-62 211.0 0.3 5.7e-62 208.7 0.1 2.2 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 KNZ82329.1 - 2e-05 23.5 0.0 0.13 10.9 0.0 2.2 2 0 0 2 2 2 2 Bacteriophage replication gene A protein (GPA) AAA_30 PF13604.1 KNZ82329.1 - 0.0011 18.6 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KNZ82329.1 - 0.098 12.6 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain SEP PF08059.8 KNZ82330.1 - 3.9e-21 75.1 0.0 7.8e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 KNZ82330.1 - 8.2e-15 54.6 0.0 1.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 UBX domain ThylakoidFormat PF11264.3 KNZ82332.1 - 0.024 14.2 0.1 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Thylakoid formation protein FlaG PF03646.10 KNZ82333.1 - 1.6e-11 44.2 0.0 24 5.0 0.0 7.3 7 1 1 8 8 8 7 FlaG protein YdfZ PF14001.1 KNZ82333.1 - 5.7e-06 26.5 0.0 1.9e+02 2.3 0.0 6.9 1 1 7 8 8 8 0 YdfZ protein YopE_N PF09020.5 KNZ82333.1 - 0.012 15.6 0.0 57 3.7 0.0 3.8 1 1 4 6 6 6 0 YopE, N terminal Pkinase PF00069.20 KNZ82334.1 - 2.8e-05 23.4 0.2 5.9e-05 22.3 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 KNZ82334.1 - 5.5e-05 22.3 0.1 0.00011 21.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KNZ82334.1 - 0.0012 18.6 0.3 0.0032 17.2 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 KNZ82334.1 - 0.0069 15.6 0.1 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.15 KNZ82334.1 - 0.016 14.8 0.0 0.04 13.4 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 KNZ82334.1 - 0.086 12.1 0.2 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 RIO1 family FAM176 PF14851.1 KNZ82335.1 - 2 8.0 6.0 1.5 8.4 3.1 1.5 1 1 0 1 1 1 0 FAM176 family Ank_2 PF12796.2 KNZ82336.1 - 2.7e-168 546.8 73.7 4.2e-25 87.9 2.7 5.7 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KNZ82336.1 - 2.5e-93 301.5 36.0 5.4e-09 35.4 0.1 12.4 8 4 4 12 12 12 12 Ankyrin repeat Ank_3 PF13606.1 KNZ82336.1 - 5.1e-77 246.0 28.5 1.1e-07 31.3 0.1 12.6 13 0 0 13 13 13 12 Ankyrin repeat Ank_4 PF13637.1 KNZ82336.1 - 6.3e-65 214.5 29.4 7.2e-10 39.1 0.1 8.6 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KNZ82336.1 - 1.5e-62 206.1 25.5 1.6e-07 31.3 0.1 11.9 3 2 9 12 12 12 12 Ankyrin repeats (many copies) D5_N PF08706.6 KNZ82336.1 - 0.00049 20.2 1.0 23 5.0 0.0 5.1 1 1 3 4 4 4 0 D5 N terminal like Archease PF01951.11 KNZ82336.1 - 0.0078 16.1 0.1 41 4.1 0.0 5.9 8 0 0 8 8 8 0 Archease protein family (MTH1598/TM1083) IL33 PF15095.1 KNZ82336.1 - 0.015 14.7 1.0 2.5 7.4 0.0 3.1 3 0 0 3 3 3 0 Interleukin 33 SCPU PF05229.10 KNZ82336.1 - 0.028 14.4 0.0 64 3.6 0.0 3.7 3 1 1 4 4 4 0 Spore Coat Protein U domain Peptidase_C23 PF05379.6 KNZ82336.1 - 0.034 14.1 0.2 13 5.7 0.0 3.3 3 0 0 3 3 3 0 Carlavirus endopeptidase Pkinase PF00069.20 KNZ82338.1 - 2.2e-70 236.8 0.0 2.7e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KNZ82338.1 - 4.1e-31 107.9 0.0 5.4e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KNZ82338.1 - 0.0045 16.7 0.1 0.019 14.7 0.0 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KNZ82338.1 - 0.022 13.5 0.0 0.09 11.5 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 Kinase-like PF14531.1 KNZ82338.1 - 0.091 11.7 0.0 0.18 10.7 0.0 1.5 1 1 1 2 2 2 0 Kinase-like ATP_bind_1 PF03029.12 KNZ82339.1 - 1.5e-75 253.8 0.0 1.9e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KNZ82339.1 - 0.00032 20.1 0.0 0.0038 16.7 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 KNZ82339.1 - 0.0013 18.2 0.1 0.0033 16.8 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain FeoB_N PF02421.13 KNZ82339.1 - 0.017 14.3 0.0 0.035 13.3 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_10 PF12846.2 KNZ82339.1 - 0.028 13.8 0.1 0.15 11.4 0.1 1.9 1 1 0 1 1 1 0 AAA-like domain PAPA-1 PF04795.7 KNZ82339.1 - 0.26 12.0 2.7 0.47 11.1 1.9 1.4 1 0 0 1 1 1 0 PAPA-1-like conserved region SAD_SRA PF02182.12 KNZ82340.1 - 4.3e-37 126.8 0.1 3.1e-35 120.7 0.1 2.0 1 1 1 2 2 2 2 SAD/SRA domain OPT PF03169.10 KNZ82341.1 - 3.4e-191 636.9 62.2 3.8e-191 636.7 43.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1242 PF06842.7 KNZ82342.1 - 1.1e-18 66.3 2.0 1.5e-18 65.9 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) LST1 PF05083.8 KNZ82342.1 - 0.73 9.8 3.6 0.24 11.3 0.6 1.6 1 1 0 1 1 1 0 LST-1 protein SMC_N PF02463.14 KNZ82343.1 - 1e-58 198.1 24.3 5e-58 195.9 16.8 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KNZ82343.1 - 4e-20 71.9 2.3 3.4e-19 68.9 0.4 3.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KNZ82343.1 - 4.1e-15 56.5 3.3 1.2e-06 28.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KNZ82343.1 - 9.4e-09 35.8 31.4 9.4e-09 35.8 21.7 6.1 2 2 0 2 2 2 1 AAA domain Reo_sigmaC PF04582.7 KNZ82343.1 - 1.7e-06 27.4 24.2 2.9e-05 23.4 3.8 4.7 3 2 1 4 4 4 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 KNZ82343.1 - 6.2e-06 25.6 0.4 4.4e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Spidroin_MaSp PF11260.3 KNZ82343.1 - 1.2 9.2 5.5 17 5.5 0.2 3.6 3 0 0 3 3 3 0 Major ampullate spidroin 1 and 2 DUF262 PF03235.9 KNZ82344.1 - 4.9e-14 52.8 0.1 1.4e-13 51.3 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF262 Herpes_IR6 PF06307.7 KNZ82344.1 - 0.037 13.3 0.5 0.069 12.4 0.4 1.4 1 0 0 1 1 1 0 Herpesvirus IR6 protein RNase_PH PF01138.16 KNZ82345.1 - 1.2e-18 67.7 0.0 1.6e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KNZ82345.1 - 1.1e-07 31.7 0.0 1.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Trm112p PF03966.11 KNZ82346.1 - 4.6e-17 62.1 0.1 6.3e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein PAAR_motif PF05488.8 KNZ82346.1 - 0.082 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 PAAR motif Dyp_perox PF04261.7 KNZ82347.1 - 4.2e-06 25.7 0.0 3.4e-05 22.7 0.0 2.5 3 1 0 3 3 3 1 Dyp-type peroxidase family Hydantoinase_A PF01968.13 KNZ82348.1 - 1.8e-89 299.6 0.0 3.4e-89 298.7 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KNZ82348.1 - 1.3e-53 181.1 0.1 1.8e-50 170.8 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region WD40 PF00400.27 KNZ82350.1 - 6.8e-42 139.8 18.1 1.6e-11 43.5 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KNZ82350.1 - 0.00017 21.3 11.5 0.06 13.0 0.5 4.1 2 2 2 4 4 4 3 Transcription factor IIIC subunit delta N-term Inositol_P PF00459.20 KNZ82351.1 - 3.1e-50 170.9 0.1 1.4e-49 168.8 0.1 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family Methyltransf_2 PF00891.13 KNZ82352.1 - 3.1e-33 114.9 0.0 1.7e-32 112.5 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KNZ82352.1 - 0.0015 18.2 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KNZ82352.1 - 0.0027 18.1 0.0 0.0055 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KNZ82352.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 KNZ82352.1 - 0.015 15.9 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GD_AH_C PF04295.8 KNZ82355.1 - 0.048 12.3 3.1 0.075 11.6 2.1 1.2 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus PIF1 PF05970.9 KNZ82356.1 - 1.7e-53 181.8 0.1 1.9e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Viral_helicase1 PF01443.13 KNZ82356.1 - 0.0066 16.0 0.1 0.016 14.7 0.1 1.7 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KNZ82356.1 - 0.03 13.9 0.0 0.046 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KNZ82356.1 - 0.052 13.7 0.1 0.24 11.5 0.1 1.9 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KNZ82356.1 - 0.11 11.9 0.2 0.28 10.5 0.1 1.6 1 1 0 2 2 2 0 AAA domain Prefoldin PF02996.12 KNZ82357.1 - 1.3e-29 102.2 1.0 1.7e-29 101.9 0.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 KNZ82357.1 - 3.8e-06 26.5 0.4 6.7e-06 25.8 0.1 1.5 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 KNZ82357.1 - 1.8e-05 24.4 3.1 0.00091 18.9 0.1 2.2 2 0 0 2 2 2 1 Prefoldin subunit COG2 PF06148.6 KNZ82357.1 - 6.1e-05 22.9 3.9 0.067 13.0 0.3 2.1 2 0 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 Cep57_MT_bd PF06657.8 KNZ82357.1 - 0.0055 16.6 2.9 0.0063 16.4 0.2 2.0 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 TACC PF05010.9 KNZ82357.1 - 0.034 13.9 2.7 0.073 12.8 1.8 1.5 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) XkdW PF09636.5 KNZ82357.1 - 0.038 13.8 0.8 0.47 10.3 0.2 2.1 2 0 0 2 2 2 0 XkdW protein Helicase_IV_N PF12462.3 KNZ82357.1 - 0.046 13.3 1.5 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal Spc7 PF08317.6 KNZ82357.1 - 0.049 12.2 8.2 0.21 10.2 0.6 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.4 KNZ82357.1 - 0.05 13.7 3.2 5.5 7.1 0.2 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3296 PF11726.3 KNZ82357.1 - 0.078 12.5 1.8 0.11 11.9 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3296) bZIP_1 PF00170.16 KNZ82357.1 - 0.095 12.6 1.2 5 7.1 0.1 2.3 2 0 0 2 2 2 0 bZIP transcription factor Mnd1 PF03962.10 KNZ82357.1 - 0.13 11.9 3.1 3.1 7.4 0.1 2.0 2 0 0 2 2 2 0 Mnd1 family YscO PF07321.7 KNZ82357.1 - 0.22 11.3 6.9 0.22 11.3 0.8 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO HSCB_C PF07743.8 KNZ82357.1 - 0.23 11.9 3.7 0.67 10.4 0.4 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain UPF0449 PF15136.1 KNZ82357.1 - 0.32 11.2 2.8 13 6.1 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 MscS_porin PF12795.2 KNZ82357.1 - 0.49 9.6 9.1 1.2 8.4 1.4 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.7 KNZ82357.1 - 0.62 9.8 5.8 7.7 6.3 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.6 KNZ82357.1 - 0.68 9.9 6.1 6.1 6.8 0.5 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Fib_alpha PF08702.5 KNZ82357.1 - 0.71 9.9 5.5 2.3 8.3 0.5 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family IL6 PF00489.12 KNZ82357.1 - 0.8 9.2 4.7 0.62 9.6 0.4 2.1 2 1 0 2 2 2 0 Interleukin-6/G-CSF/MGF family IncA PF04156.9 KNZ82357.1 - 0.93 9.0 5.0 1.2 8.6 0.8 2.0 2 0 0 2 2 2 0 IncA protein DUF1409 PF07197.7 KNZ82357.1 - 1.4 9.0 4.4 3.9 7.6 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) DUF4559 PF15112.1 KNZ82357.1 - 1.6 7.8 5.6 4.9 6.2 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) DUF2347 PF09804.4 KNZ82358.1 - 2.8e-50 171.2 0.0 3.8e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 KNZ82358.1 - 1.4e-05 24.7 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KNZ82358.1 - 0.00023 19.7 0.0 1.4 7.3 0.0 3.1 3 0 0 3 3 3 2 Transport protein Avl9 F-box-like PF12937.2 KNZ82359.1 - 1.8e-07 30.7 0.8 1.3e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 F-box-like GTP_EFTU PF00009.22 KNZ82360.1 - 5.9e-58 195.4 0.0 1.6e-57 193.9 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KNZ82360.1 - 5.4e-35 119.5 0.1 1.3e-34 118.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 KNZ82360.1 - 1.1e-29 102.0 0.0 2.3e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KNZ82360.1 - 3.9e-22 77.9 0.0 1.3e-21 76.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KNZ82360.1 - 9.5e-13 48.0 0.0 3.2e-12 46.4 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 KNZ82360.1 - 0.025 14.0 0.1 0.54 9.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AhpC-TSA PF00578.16 KNZ82361.1 - 4.5e-37 126.4 0.0 6.4e-36 122.7 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family 1-cysPrx_C PF10417.4 KNZ82361.1 - 5e-14 51.6 0.0 9e-14 50.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 KNZ82361.1 - 2.5e-12 46.5 0.0 3.4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin RNase_H PF00075.19 KNZ82366.1 - 7.5e-05 23.0 0.1 0.0001 22.6 0.1 1.2 1 0 0 1 1 1 1 RNase H Gti1_Pac2 PF09729.4 KNZ82367.1 - 3.6e-42 144.1 0.1 5.2e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Gti1/Pac2 family HnRNP_M PF11532.3 KNZ82367.1 - 0.063 13.3 0.1 0.19 11.8 0.0 1.9 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M WSC PF01822.14 KNZ82368.1 - 2.2e-51 171.6 45.2 7.2e-15 54.6 2.5 4.5 4 1 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 KNZ82368.1 - 3.5e-21 75.4 0.0 5.9e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KNZ82368.1 - 1.2e-14 54.1 0.1 2.4e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyco_trans_2_3 PF13632.1 KNZ82369.1 - 8.3e-39 133.3 2.2 8.3e-39 133.3 1.5 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KNZ82369.1 - 0.00064 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KNZ82369.1 - 0.012 15.2 0.0 0.14 11.8 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KNZ82369.1 - 0.036 13.3 0.0 0.13 11.4 0.0 1.9 3 0 0 3 3 3 0 Glycosyl transferase family 21 DUF842 PF05811.8 KNZ82369.1 - 0.097 12.1 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF4131 PF13567.1 KNZ82369.1 - 9 5.6 12.5 12 5.2 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Glyco_hydro_16 PF00722.16 KNZ82370.1 - 9.7e-20 70.6 0.1 2.1e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SAC3_GANP PF03399.11 KNZ82371.1 - 1.4e-23 83.5 0.2 2.4e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family FHA PF00498.21 KNZ82372.1 - 3.1e-12 46.4 0.1 7.7e-12 45.1 0.1 1.7 1 0 0 1 1 1 1 FHA domain EMP24_GP25L PF01105.19 KNZ82372.1 - 0.12 12.1 1.4 0.31 10.7 0.8 1.8 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD IncA PF04156.9 KNZ82372.1 - 0.29 10.7 6.2 18 4.8 4.3 2.5 1 1 0 1 1 1 0 IncA protein DUF3573 PF12097.3 KNZ82372.1 - 0.62 8.6 1.7 1.8 7.1 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) FlxA PF14282.1 KNZ82372.1 - 2.2 8.2 7.3 0.96 9.4 0.2 3.0 3 0 0 3 3 3 0 FlxA-like protein Sugar_tr PF00083.19 KNZ82374.1 - 7.6e-119 397.2 28.7 8.7e-119 397.0 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KNZ82374.1 - 1.3e-18 66.8 45.4 6.4e-14 51.4 13.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KNZ82374.1 - 0.033 14.2 0.4 0.033 14.2 0.3 3.7 4 1 1 5 5 5 0 Protein of unknown function (DUF1228) MAGE PF01454.14 KNZ82375.1 - 1.5e-34 119.0 0.3 9.7e-31 106.6 0.0 2.1 2 0 0 2 2 2 2 MAGE family FAA_hydrolase PF01557.13 KNZ82376.1 - 1.4e-50 171.8 0.0 1.9e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family zf-MYND PF01753.13 KNZ82379.1 - 0.035 13.9 0.2 0.1 12.4 0.2 1.8 1 0 0 1 1 1 0 MYND finger Pox_A6 PF04924.7 KNZ82382.1 - 0.12 11.1 0.0 0.13 10.9 0.0 1.0 1 0 0 1 1 1 0 Poxvirus A6 protein Helitron_like_N PF14214.1 KNZ82385.1 - 8.6e-05 22.3 0.3 0.00032 20.4 0.1 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus BCAS2 PF05700.6 KNZ82386.1 - 0.093 12.1 3.4 0.15 11.4 2.3 1.4 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF2580 PF10824.3 KNZ82386.1 - 0.13 12.6 1.6 4.4 7.7 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2580) SRCR_2 PF15494.1 KNZ82389.1 - 0.056 13.6 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain Peptidase_S9 PF00326.16 KNZ82390.1 - 2.4e-38 131.4 0.0 6.8e-38 130.0 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KNZ82390.1 - 1.1e-11 44.7 0.0 1.8e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KNZ82390.1 - 5.1e-06 25.9 0.0 9e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 KNZ82390.1 - 2.6e-05 24.1 0.2 6.9e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KNZ82390.1 - 9.2e-05 22.1 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PD40 PF07676.7 KNZ82390.1 - 0.0018 17.8 0.4 0.63 9.7 0.0 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 KNZ82390.1 - 0.0036 15.9 0.0 0.063 11.8 0.0 2.2 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF4485 PF14846.1 KNZ82391.1 - 0.029 14.0 0.7 0.1 12.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) FAIM1 PF06905.8 KNZ82392.1 - 0.024 13.8 0.1 0.056 12.6 0.1 1.6 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1)