# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- NCA2 PF08637.10 GAM33242.1 - 4e-101 338.0 0.1 6.1e-101 337.4 0.1 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 S100PBPR PF15427.6 GAM33242.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 S100P-binding protein AAA PF00004.29 GAM33243.1 - 1.4e-65 219.6 0.3 8.1e-40 136.3 0.0 4.8 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 GAM33243.1 - 1.8e-64 216.2 0.1 1e-63 213.8 0.0 2.0 2 0 0 2 2 2 1 Ras family Roc PF08477.13 GAM33243.1 - 1e-34 119.3 0.2 2.6e-32 111.6 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_lid_3 PF17862.1 GAM33243.1 - 2.3e-16 59.3 0.2 5.1e-11 42.2 0.1 2.9 2 0 0 2 2 2 2 AAA+ lid domain RRM_1 PF00076.22 GAM33243.1 - 1.6e-14 53.5 0.0 2.1e-13 49.9 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 GAM33243.1 - 3.1e-13 50.5 2.6 0.0039 17.6 0.1 5.4 3 2 1 5 5 5 2 AAA ATPase domain Arf PF00025.21 GAM33243.1 - 5e-13 48.9 0.1 1e-11 44.6 0.0 3.0 4 0 0 4 4 3 1 ADP-ribosylation factor family AAA_22 PF13401.6 GAM33243.1 - 9e-10 39.0 2.6 0.031 14.6 0.1 5.4 4 2 1 5 5 4 2 AAA domain AAA_5 PF07728.14 GAM33243.1 - 2.5e-08 34.0 1.0 0.078 13.0 0.1 4.4 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GAM33243.1 - 3.1e-07 30.1 0.0 0.29 10.6 0.0 3.7 3 1 0 3 3 3 2 P-loop containing dynein motor region AAA_14 PF13173.6 GAM33243.1 - 2.2e-05 24.5 0.0 0.37 10.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 GAM33243.1 - 2.7e-05 24.5 0.0 0.15 12.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 GAM33243.1 - 3.2e-05 23.7 0.0 0.34 10.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 GAM33243.1 - 3.4e-05 23.9 0.1 0.0023 17.9 0.0 2.9 3 0 0 3 3 3 1 Rad17 P-loop domain RNA_helicase PF00910.22 GAM33243.1 - 5.1e-05 23.6 0.0 1.4 9.4 0.0 3.7 3 0 0 3 3 3 2 RNA helicase NACHT PF05729.12 GAM33243.1 - 5.4e-05 23.2 2.2 0.98 9.3 0.1 4.5 3 2 1 4 4 4 1 NACHT domain IstB_IS21 PF01695.17 GAM33243.1 - 8.5e-05 22.3 0.0 1.3 8.7 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein RsgA_GTPase PF03193.16 GAM33243.1 - 0.00012 22.0 1.2 4.6 7.1 0.0 3.9 4 0 0 4 4 3 0 RsgA GTPase RuvB_N PF05496.12 GAM33243.1 - 0.00016 21.5 0.0 0.011 15.4 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAM33243.1 - 0.00018 21.7 0.0 0.53 10.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 GAM33243.1 - 0.00018 21.2 0.0 0.49 10.2 0.0 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain DUF815 PF05673.13 GAM33243.1 - 0.00019 20.7 0.1 0.91 8.6 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF815) GTP_EFTU PF00009.27 GAM33243.1 - 0.0002 21.0 0.0 0.00079 19.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM33243.1 - 0.00038 20.5 0.0 0.19 11.8 0.0 3.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 GAM33243.1 - 0.00048 20.7 0.3 3 8.4 0.0 4.0 4 0 0 4 4 3 1 ABC transporter AAA_25 PF13481.6 GAM33243.1 - 0.00061 19.4 0.9 5.4 6.6 0.0 4.4 3 1 0 4 4 4 0 AAA domain AAA_2 PF07724.14 GAM33243.1 - 0.00078 19.6 0.0 0.13 12.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Gtr1_RagA PF04670.12 GAM33243.1 - 0.00093 18.6 0.1 0.0055 16.1 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAM33243.1 - 0.001 18.6 0.1 2.7 7.4 0.0 3.5 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit TniB PF05621.11 GAM33243.1 - 0.0024 17.3 0.0 25 4.2 0.0 4.3 4 0 0 4 4 4 0 Bacterial TniB protein TIP49 PF06068.13 GAM33243.1 - 0.0024 17.1 0.1 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 GAM33243.1 - 0.0034 17.9 0.3 3.1 8.3 0.1 3.7 3 1 0 3 3 3 1 AAA domain MCM PF00493.23 GAM33243.1 - 0.0037 16.4 0.0 9.4 5.3 0.0 3.3 3 0 0 3 3 3 0 MCM P-loop domain Sigma54_activat PF00158.26 GAM33243.1 - 0.0077 16.0 0.1 4.3 7.0 0.0 4.0 4 1 1 5 5 4 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 GAM33243.1 - 0.014 14.7 0.8 2.7 7.3 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 GAM33243.1 - 0.015 15.8 0.0 0.049 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 GAM33243.1 - 0.019 15.1 0.0 1.5 8.9 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_11 PF13086.6 GAM33243.1 - 0.023 14.5 0.0 9.6 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAM33243.1 - 0.027 14.4 3.2 3.8 7.4 0.0 4.1 3 2 2 5 5 5 0 ATPase domain predominantly from Archaea ATPase PF06745.13 GAM33243.1 - 0.029 13.7 0.1 16 4.7 0.0 3.6 4 0 0 4 4 3 0 KaiC AAA_30 PF13604.6 GAM33243.1 - 0.046 13.4 0.0 1.8 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 GAM33243.1 - 0.059 13.4 0.1 16 5.6 0.0 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 GAM33243.1 - 0.064 13.0 0.1 8.3 6.1 0.0 3.4 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 GAM33243.1 - 0.065 13.7 0.0 16 5.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain DAP3 PF10236.9 GAM33243.1 - 0.12 11.6 0.0 6.2 5.9 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 PI3_PI4_kinase PF00454.27 GAM33244.1 - 1.7e-42 145.9 0.0 3.9e-42 144.8 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 GAM33244.1 - 1.3e-36 126.6 1.4 1.3e-36 126.6 1.4 1.8 2 0 0 2 2 2 1 FAT domain UME PF08064.13 GAM33244.1 - 6.7e-32 109.4 0.2 3.6e-31 107.1 0.2 2.5 1 0 0 1 1 1 1 UME (NUC010) domain TPR_19 PF14559.6 GAM33244.1 - 0.015 15.8 0.2 0.16 12.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3385 PF11865.8 GAM33244.1 - 0.022 14.7 0.0 0.14 12.0 0.0 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) NADH-u_ox-rdase PF10785.9 GAM33245.1 - 2.8e-27 95.2 0.1 5.7e-27 94.2 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 GAM33245.1 - 1.3e-25 89.1 0.1 2e-25 88.6 0.1 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.12 GAM33246.1 - 1.8e-35 120.8 0.7 6.6e-35 119.0 0.8 1.8 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 Med5 PF08689.10 GAM33246.1 - 0.22 9.3 5.4 1.5 6.5 0.6 2.4 1 1 0 2 2 2 0 Mediator complex subunit Med5 FGGY_C PF02782.16 GAM33247.1 - 9.7e-50 169.0 0.1 1.6e-49 168.3 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GAM33247.1 - 2.6e-22 79.6 0.0 7.3e-21 74.9 0.0 2.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 GAM33247.1 - 0.0087 15.6 0.0 0.096 12.2 0.0 2.3 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.17 GAM33247.1 - 0.25 11.2 1.2 2.3 8.1 0.2 2.4 2 0 0 2 2 2 0 Transposase BK_channel_a PF03493.18 GAM33248.1 - 0.076 13.2 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit Y_phosphatase PF00102.27 GAM33249.1 - 2.1e-57 194.4 0.7 9.7e-57 192.2 0.7 2.0 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 GAM33249.1 - 1.5e-08 35.1 0.0 5.5e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain ApoLp-III PF07464.11 GAM33249.1 - 0.024 14.7 0.2 0.044 13.9 0.2 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Y_phosphatase3 PF13350.6 GAM33249.1 - 0.039 13.9 0.1 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.20 GAM33249.1 - 0.061 13.1 0.0 0.23 11.3 0.0 2.0 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain COX16 PF14138.6 GAM33250.1 - 7.9e-30 103.2 0.1 1e-29 102.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DUF3311 PF11755.8 GAM33250.1 - 0.045 13.7 0.2 0.073 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) Nic96 PF04097.14 GAM33251.1 - 8.9e-217 721.4 0.0 1.3e-216 720.9 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Na_Ca_ex PF01699.24 GAM33252.1 - 3.5e-21 75.7 34.7 1.6e-15 57.4 12.9 3.7 5 1 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 GAM33252.1 - 3.9e-15 56.3 7.3 3.9e-15 56.3 7.3 4.7 5 0 0 5 5 5 2 Inner membrane component domain AAA PF00004.29 GAM33253.1 - 5e-44 149.9 0.0 8.3e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM33253.1 - 4.9e-14 51.9 0.0 1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 GAM33253.1 - 1.5e-07 31.7 0.0 2.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAM33253.1 - 4.6e-07 29.9 0.0 1.2e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM33253.1 - 1e-06 29.2 0.0 4.3e-05 24.0 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 GAM33253.1 - 3.9e-06 26.7 2.9 1e-05 25.4 2.9 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 GAM33253.1 - 1.4e-05 25.4 0.1 0.0063 16.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 GAM33253.1 - 6.6e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAM33253.1 - 0.00045 20.8 0.0 0.029 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAM33253.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 GAM33253.1 - 0.0011 18.2 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 GAM33253.1 - 0.002 18.3 0.0 0.004 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 GAM33253.1 - 0.0052 16.6 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 GAM33253.1 - 0.0079 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 GAM33253.1 - 0.008 15.6 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 GAM33253.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 GAM33253.1 - 0.012 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 GAM33253.1 - 0.022 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 GAM33253.1 - 0.022 14.4 0.0 0.094 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 GAM33253.1 - 0.025 14.0 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 GAM33253.1 - 0.026 14.1 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region HR1 PF02185.16 GAM33253.1 - 0.037 14.1 0.8 0.095 12.8 0.8 1.7 1 0 0 1 1 1 0 Hr1 repeat RNA_helicase PF00910.22 GAM33253.1 - 0.038 14.4 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 GAM33253.1 - 0.039 13.7 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 GAM33253.1 - 0.04 13.9 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAM33253.1 - 0.063 12.8 0.1 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 GAM33253.1 - 0.068 12.8 0.2 0.24 11.1 0.2 2.0 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Parvo_NS1 PF01057.17 GAM33253.1 - 0.09 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 GAM33253.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2072 PF09845.9 GAM33253.1 - 0.16 12.2 0.1 0.3 11.4 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein F-box-like PF12937.7 GAM33254.1 - 0.00061 19.6 0.3 0.0072 16.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like UFD1 PF03152.14 GAM33255.1 - 1.2e-29 103.0 0.0 4.5e-26 91.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 GAM33255.1 - 1.1e-06 28.8 0.3 4.7e-06 26.7 0.3 2.1 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zinc_ribbon_4 PF13717.6 GAM33255.1 - 0.32 11.0 5.4 14 5.7 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Yip1 PF04893.17 GAM33256.1 - 9e-06 25.5 17.4 0.0003 20.6 9.5 2.3 2 0 0 2 2 2 2 Yip1 domain Bac_surface_Ag PF01103.23 GAM33257.1 - 4e-45 154.7 0.5 6.4e-45 154.0 0.5 1.3 1 0 0 1 1 1 1 Surface antigen Pkinase PF00069.25 GAM33257.1 - 1.3e-05 24.7 0.0 2.7e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GAM33257.1 - 0.002 18.1 0.1 0.0054 16.7 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAM33257.1 - 0.014 14.2 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 GAM33257.1 - 0.019 14.5 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase UQ_con PF00179.26 GAM33258.1 - 1.4e-19 70.2 0.1 2e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Cyto_heme_lyase PF01265.17 GAM33259.1 - 2e-126 421.5 3.7 2.3e-126 421.3 3.7 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ABC1 PF03109.16 GAM33260.1 - 6.6e-20 71.5 0.0 8.4e-11 42.1 0.0 2.7 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 GAM33260.1 - 0.048 13.6 0.1 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 GAM33260.1 - 0.055 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family MFS_1 PF07690.16 GAM33261.1 - 2.4e-27 95.8 53.7 6.9e-25 87.7 41.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM33261.1 - 2.1e-05 23.6 11.9 2.1e-05 23.6 11.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter FAD_binding_3 PF01494.19 GAM33262.1 - 2e-18 66.8 0.0 8.3e-10 38.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAM33262.1 - 1.8e-10 40.9 1.1 0.00011 21.9 0.1 2.9 1 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 GAM33262.1 - 4.5e-06 26.0 0.0 1.3e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 GAM33262.1 - 8.2e-06 25.2 0.0 0.0041 16.4 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 GAM33262.1 - 4.4e-05 22.7 0.0 0.19 10.8 0.0 2.6 2 1 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.6 GAM33262.1 - 6e-05 23.2 0.1 0.00026 21.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAM33262.1 - 0.00033 19.6 0.4 0.0052 15.7 0.1 2.3 2 1 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 GAM33262.1 - 0.0011 19.4 0.0 0.062 13.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM33262.1 - 0.0098 14.6 0.1 0.051 12.3 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAM33262.1 - 0.011 15.0 0.0 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM33262.1 - 0.014 14.5 0.1 0.036 13.1 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 GAM33262.1 - 0.016 14.5 0.1 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 GAM33262.1 - 0.034 13.2 0.3 0.29 10.1 0.4 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 GAM33262.1 - 0.11 11.8 1.4 6.2 6.0 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 GAM33262.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 GAM33262.1 - 0.2 10.9 0.2 0.57 9.5 0.2 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase MFS_1 PF07690.16 GAM33263.1 - 6.6e-37 127.3 42.6 2.3e-36 125.4 42.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM33263.1 - 6.1e-06 24.9 15.9 8.7e-06 24.4 15.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMC PF07810.13 GAM33263.1 - 0.54 10.9 5.4 0.084 13.5 0.8 2.0 2 0 0 2 2 2 0 TMC domain p450 PF00067.22 GAM33264.1 - 1.7e-29 102.9 0.0 2.3e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 GAM33265.1 - 1e-16 60.9 0.0 1.6e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 GAM33265.1 - 8.2e-05 22.5 0.1 0.00023 21.1 0.1 1.8 1 1 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 GAM33265.1 - 0.00044 20.2 0.0 0.00083 19.3 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Cep57_MT_bd PF06657.13 GAM33265.1 - 0.086 13.3 0.0 0.47 11.0 0.0 2.2 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Haem_oxygenas_2 PF14518.6 GAM33266.1 - 3.6e-34 118.1 0.9 6e-34 117.4 0.9 1.4 1 0 0 1 1 1 1 Iron-containing redox enzyme Chorismate_bind PF00425.18 GAM33267.1 - 5.8e-89 298.1 0.0 8.3e-89 297.6 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 GAM33267.1 - 1.6e-24 86.8 0.0 1.2e-20 74.2 0.0 3.3 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region DIOX_N PF14226.6 GAM33267.1 - 1.2e-08 35.7 0.0 3e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM33267.1 - 0.00046 20.6 0.0 0.0018 18.7 0.0 2.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 GAM33268.1 - 3.2e-68 230.3 0.0 4.2e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 GAM33268.1 - 1.5e-20 74.4 0.0 3.4e-20 73.1 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 GAM33268.1 - 8.1e-07 29.3 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 GAM33268.1 - 0.0021 18.7 0.1 0.0051 17.4 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AMP-binding_C PF13193.6 GAM33268.1 - 0.015 16.3 0.1 0.036 15.0 0.1 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Hydrolase_4 PF12146.8 GAM33268.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 COesterase PF00135.28 GAM33269.1 - 1.5e-94 317.7 0.0 1.8e-94 317.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM33269.1 - 0.0031 17.4 0.1 0.0065 16.3 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold ADH_zinc_N_2 PF13602.6 GAM33270.1 - 2.2e-14 54.7 0.0 3.3e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAM33270.1 - 1.2e-10 41.5 0.1 2.1e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAM33270.1 - 0.0025 17.3 0.0 0.051 13.0 0.0 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus DapB_N PF01113.20 GAM33270.1 - 0.0059 16.7 0.0 0.009 16.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 GAM33270.1 - 0.072 13.5 0.1 0.1 13.0 0.1 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 GAM33270.1 - 0.082 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain GATase PF00117.28 GAM33271.1 - 3e-48 164.1 0.0 3.6e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAM33271.1 - 1.8e-05 24.6 0.5 0.00025 20.9 0.5 2.1 1 1 0 1 1 1 1 Peptidase C26 Peripla_BP_2 PF01497.18 GAM33271.1 - 8.2e-05 22.3 0.0 0.00028 20.5 0.0 1.7 2 0 0 2 2 2 1 Periplasmic binding protein DUF3245 PF11595.8 GAM33273.1 - 1.6e-21 77.3 18.8 1.7e-10 41.5 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF3245) Spt20 PF12090.8 GAM33273.1 - 1.1 8.9 12.1 1.9 8.1 12.1 1.4 1 0 0 1 1 1 0 Spt20 family F-protein PF00469.20 GAM33273.1 - 1.5 8.4 8.2 0.94 9.0 6.4 1.5 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef SAPS PF04499.15 GAM33273.1 - 4.5 5.9 12.3 6 5.5 12.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 GAM33273.1 - 4.7 5.4 15.0 5.6 5.1 15.0 1.1 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 GAM33273.1 - 6.1 5.6 5.0 7.2 5.3 5.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter HSF_DNA-bind PF00447.17 GAM33274.1 - 5.1e-30 103.9 2.1 5.1e-30 103.9 2.1 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding F-box-like PF12937.7 GAM33275.1 - 0.00031 20.6 0.2 0.00076 19.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM33275.1 - 0.0021 17.9 0.1 0.0054 16.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 GAM33275.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain DUF1479 PF07350.12 GAM33276.1 - 2.3e-125 418.7 0.0 2.8e-125 418.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Sugar_tr PF00083.24 GAM33277.1 - 3.2e-79 266.9 21.4 3.7e-79 266.7 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM33277.1 - 2.4e-21 76.1 52.8 2.6e-19 69.3 28.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM33277.1 - 2.9e-06 26.0 3.5 5.7e-06 25.0 3.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 GAM33278.1 - 5.4e-30 104.5 48.2 2e-29 102.6 38.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM33278.1 - 1.4e-06 27.4 32.8 0.00019 20.4 15.1 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 GAM33278.1 - 0.00015 20.8 25.7 0.0028 16.6 10.0 2.3 2 1 0 2 2 2 2 MFS_1 like family Fungal_trans PF04082.18 GAM33279.1 - 9.9e-25 87.1 0.0 2e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM33279.1 - 1.1e-05 25.4 15.0 1.9e-05 24.7 15.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonuc_L-PSP PF01042.21 GAM33280.1 - 9.1e-18 64.4 0.0 1.2e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP NOGCT PF08155.11 GAM33280.1 - 0.037 14.0 0.2 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 NOGCT (NUC087) domain Invasin_D3 PF09134.10 GAM33280.1 - 0.15 12.4 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Invasin, domain 3 Abhydrolase_1 PF00561.20 GAM33281.1 - 4.2e-16 59.4 0.1 9.1e-16 58.3 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM33281.1 - 5.7e-07 30.4 0.0 7.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM33281.1 - 0.00093 18.5 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 p450 PF00067.22 GAM33282.1 - 2.9e-57 194.4 0.0 3.3e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 GAM33283.1 - 6.4e-31 107.7 0.0 5.4e-30 104.7 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM33283.1 - 9.9e-23 80.6 0.0 1.8e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM33283.1 - 9.4e-07 28.9 0.0 3e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAM33283.1 - 9.7e-05 22.3 0.1 0.00042 20.3 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H-binding RNAse_A_bac PF18431.1 GAM33283.1 - 0.014 16.3 0.1 0.037 15.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial CdiA-CT RNAse A domain NmrA PF05368.13 GAM33283.1 - 0.017 14.7 0.1 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 GAM33283.1 - 0.032 13.6 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAM33283.1 - 0.038 13.5 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 GAM33283.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain p450 PF00067.22 GAM33284.1 - 2.9e-43 148.3 0.0 1.3e-42 146.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 GAM33285.1 - 4.8e-63 213.4 48.0 5.8e-63 213.2 48.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM33285.1 - 1.6e-21 76.5 42.8 2.2e-21 76.0 42.8 1.1 1 0 0 1 1 1 1 Amino acid permease ATP-grasp_2 PF08442.10 GAM33286.1 - 1.3e-75 253.4 0.3 1.3e-75 253.4 0.3 2.0 3 0 0 3 3 3 1 ATP-grasp domain adh_short PF00106.25 GAM33286.1 - 3.4e-42 144.1 1.0 1.2e-40 139.0 0.0 3.1 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33286.1 - 1.7e-28 99.8 0.1 6.7e-28 97.8 0.0 2.0 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Ligase_CoA PF00549.19 GAM33286.1 - 2.5e-23 82.6 0.2 5.2e-23 81.5 0.2 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 GAM33286.1 - 7.9e-08 32.0 0.4 3.3e-07 30.0 0.4 2.0 1 1 0 1 1 1 1 ATP-grasp domain DUF1776 PF08643.10 GAM33286.1 - 0.00029 20.3 0.0 0.0015 18.0 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) GARS_A PF01071.19 GAM33286.1 - 0.00068 19.5 1.0 0.026 14.3 0.2 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NmrA PF05368.13 GAM33286.1 - 0.0026 17.4 0.0 0.0061 16.2 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family Succ_CoA_lig PF13607.6 GAM33286.1 - 0.044 13.6 0.1 4.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain SMC_hinge PF06470.13 GAM33286.1 - 0.11 12.8 0.0 3.2 8.1 0.0 2.7 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain Pribosyltran PF00156.27 GAM33287.1 - 3.4e-07 29.9 0.0 5.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DPM3 PF08285.11 GAM33288.1 - 1.3e-24 86.2 0.1 1.3e-24 86.1 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) LapA_dom PF06305.11 GAM33288.1 - 0.034 14.0 0.0 0.082 12.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain EMC3_TMCO1 PF01956.16 GAM33288.1 - 0.051 13.3 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like LGT PF01790.18 GAM33288.1 - 0.057 12.7 0.0 0.063 12.5 0.0 1.1 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase NIL PF09383.10 GAM33288.1 - 0.14 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 NIL domain KAP PF05804.12 GAM33289.1 - 2.4e-05 22.7 1.3 0.00022 19.5 0.2 2.1 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) Rpr2 PF04032.16 GAM33289.1 - 0.022 15.0 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Oxidored-like PF09791.9 GAM33290.1 - 4.1e-24 84.0 2.4 9.8e-24 82.8 2.4 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 GAM33290.1 - 0.08 12.9 3.1 0.16 11.9 3.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5522) Ribosomal_L13e PF01294.18 GAM33292.1 - 1.6e-76 256.2 5.0 2.2e-76 255.7 5.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e LRR_8 PF13855.6 GAM33294.1 - 1e-24 86.1 55.2 3.9e-06 26.5 6.4 8.7 5 2 4 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 GAM33294.1 - 1.1e-22 79.7 61.3 0.00098 19.5 2.4 10.0 3 3 5 10 10 10 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM33294.1 - 0.019 15.4 50.0 5.9 7.9 0.3 12.4 12 2 0 12 12 12 0 Leucine Rich Repeat LRR_9 PF14580.6 GAM33294.1 - 0.093 12.2 18.6 1.9 7.9 3.5 5.2 2 2 1 5 5 5 0 Leucine-rich repeat LRRFIP PF09738.9 GAM33294.1 - 0.1 12.1 0.7 0.26 10.7 0.7 1.6 1 0 0 1 1 1 0 LRRFIP family LRR_6 PF13516.6 GAM33294.1 - 0.68 10.1 31.0 8.4 6.7 0.2 9.6 9 0 0 9 9 9 0 Leucine Rich repeat GCIP PF13324.6 GAM33295.1 - 2.3e-24 86.4 9.0 4.7e-24 85.4 9.0 1.5 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting YL1 PF05764.13 GAM33295.1 - 0.013 15.6 4.8 0.013 15.6 4.8 2.1 2 0 0 2 2 2 0 YL1 nuclear protein Cnd1_N PF12922.7 GAM33295.1 - 0.051 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term BUD22 PF09073.10 GAM33295.1 - 0.063 12.6 7.0 0.093 12.1 7.0 1.2 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 GAM33295.1 - 1.7 8.3 13.0 3 7.5 13.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Actin PF00022.19 GAM33296.1 - 6.3e-85 285.2 0.0 3.9e-84 282.6 0.0 1.8 1 1 0 1 1 1 1 Actin 3HCDH_N PF02737.18 GAM33297.1 - 2.9e-52 177.2 0.7 2.9e-52 177.2 0.7 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 GAM33297.1 - 1.3e-34 118.7 0.0 3.7e-34 117.2 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 GAM33297.1 - 0.00043 20.6 0.1 0.00091 19.5 0.1 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 GAM33297.1 - 0.0011 19.2 0.7 0.0049 17.0 0.7 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 GAM33297.1 - 0.023 14.1 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 GAM33297.1 - 0.024 14.2 0.1 0.034 13.7 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM33297.1 - 0.041 13.1 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FeoC PF09012.10 GAM33297.1 - 0.22 11.6 0.0 0.76 9.9 0.0 1.9 2 0 0 2 2 2 0 FeoC like transcriptional regulator TIMELESS PF04821.14 GAM33298.1 - 1.2e-87 293.7 0.2 1.2e-87 293.7 0.2 2.4 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 GAM33298.1 - 9.5e-51 173.6 1.4 9.5e-51 173.6 1.4 4.1 3 1 1 4 4 4 1 Timeless protein C terminal region PhzC-PhzF PF02567.16 GAM33299.1 - 1.3e-37 129.8 0.0 3.9e-37 128.2 0.0 1.7 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Tfb2 PF03849.14 GAM33300.1 - 3.2e-138 460.5 0.0 5.8e-138 459.7 0.0 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Tfb2_C PF18307.1 GAM33300.1 - 1.3e-22 79.9 0.1 2.8e-22 78.9 0.1 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 GAM33300.1 - 3.8e-05 23.8 0.0 0.0001 22.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 4HBT PF03061.22 GAM33301.1 - 3.1e-15 56.3 0.0 4.3e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 GAM33301.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Aquarius_N PF16399.5 GAM33302.1 - 0 1096.6 0.5 0 1096.2 0.5 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 GAM33302.1 - 1.5e-27 96.6 0.0 2.7e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAM33302.1 - 2.5e-23 83.2 0.0 7.9e-23 81.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM33302.1 - 9e-08 32.1 0.0 0.00041 20.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 GAM33302.1 - 5.1e-06 26.6 0.0 1.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAM33302.1 - 6e-06 26.7 0.0 2e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 GAM33302.1 - 0.0015 17.9 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 GAM33302.1 - 0.003 18.0 0.0 0.0089 16.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 GAM33302.1 - 0.005 16.6 0.1 0.44 10.2 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 GAM33302.1 - 0.0064 16.0 1.4 0.065 12.7 0.1 3.0 2 2 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 GAM33302.1 - 0.022 15.2 1.9 0.061 13.7 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain UvrD_C_2 PF13538.6 GAM33302.1 - 0.029 14.2 1.4 0.076 12.9 0.5 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 GAM33302.1 - 0.042 13.1 1.5 0.054 12.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 GAM33302.1 - 0.067 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase NB-ARC PF00931.22 GAM33302.1 - 0.068 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.17 GAM33302.1 - 0.096 11.8 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 GAM33302.1 - 0.1 12.9 0.0 0.44 10.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAM33302.1 - 0.1 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) efThoc1 PF11957.8 GAM33303.1 - 1.9e-151 505.1 7.6 2.7e-151 504.6 7.6 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Homeodomain PF00046.29 GAM33304.1 - 1e-13 50.9 1.8 1.9e-13 50.0 1.8 1.4 1 0 0 1 1 1 1 Homeodomain Adaptin_N PF01602.20 GAM33306.1 - 1.3e-127 426.6 4.6 1.5e-127 426.3 4.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 GAM33306.1 - 7.8e-46 154.9 0.0 1.8e-45 153.7 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 GAM33306.1 - 3.7e-20 72.3 0.0 1.1e-19 70.8 0.0 1.8 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 GAM33306.1 - 0.0001 22.4 0.6 0.01 15.9 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Ala_racemase_N PF01168.20 GAM33307.1 - 5.6e-19 68.7 0.0 1e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Epimerase PF01370.21 GAM33308.1 - 8.8e-14 51.5 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAM33308.1 - 1.5e-06 28.0 0.0 0.0062 16.1 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family RmlD_sub_bind PF04321.17 GAM33308.1 - 7e-05 22.1 0.0 0.0028 16.8 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 GAM33308.1 - 0.0014 17.7 0.0 0.032 13.2 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAM33308.1 - 0.0025 17.7 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAM33308.1 - 0.009 15.4 0.1 0.025 14.0 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 GAM33308.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 GAM33308.1 - 0.019 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 GAM33308.1 - 0.15 12.0 0.1 1.4 8.8 0.0 2.4 2 1 0 2 2 2 0 KR domain Hist_deacetyl PF00850.19 GAM33309.1 - 6.7e-54 183.4 0.0 1.1e-53 182.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.11 GAM33309.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 RTP801 C-terminal region Methyltransf_23 PF13489.6 GAM33310.1 - 1.6e-21 76.9 0.0 2.8e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM33310.1 - 1.5e-12 48.1 0.0 3.8e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain zf-AN1 PF01428.16 GAM33310.1 - 7.3e-12 45.3 18.2 3.1e-11 43.3 10.9 2.3 2 0 0 2 2 2 2 AN1-like Zinc finger Methyltransf_12 PF08242.12 GAM33310.1 - 1.4e-08 35.4 0.0 6.4e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM33310.1 - 1.5e-08 35.2 0.0 4.9e-08 33.5 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM33310.1 - 2e-08 34.2 0.0 1.2e-07 31.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM33310.1 - 2.7e-05 23.6 0.0 0.00013 21.4 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 GAM33310.1 - 5.9e-05 23.3 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 GAM33310.1 - 0.0024 17.3 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 GAM33310.1 - 0.0077 15.8 0.0 0.021 14.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 GAM33310.1 - 0.032 13.5 0.0 0.076 12.3 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 GAM33310.1 - 0.035 13.8 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 GAM33310.1 - 0.049 12.9 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 GAM33310.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Transp_Tc5_C PF04236.15 GAM33310.1 - 0.2 12.1 2.8 0.43 11.0 2.8 1.6 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain GFO_IDH_MocA PF01408.22 GAM33311.1 - 8e-24 84.8 0.0 1.3e-23 84.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 GAM33311.1 - 0.00074 20.2 0.0 0.0012 19.5 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GTF2I PF02946.14 GAM33311.1 - 0.1 12.7 0.0 0.6 10.2 0.0 2.2 2 0 0 2 2 2 0 GTF2I-like repeat MARVEL PF01284.23 GAM33312.1 - 2.2e-07 31.0 14.4 3.2e-07 30.5 14.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF998 PF06197.13 GAM33312.1 - 0.014 15.0 12.2 0.019 14.6 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) PSI_PsaF PF02507.15 GAM33312.1 - 0.089 12.6 1.2 0.12 12.3 1.2 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Chitin_synth_1 PF01644.17 GAM33313.1 - 2.2e-78 261.9 0.1 3.1e-78 261.4 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 GAM33313.1 - 2.6e-28 97.8 0.2 5.5e-28 96.7 0.2 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAM33313.1 - 2.4e-23 82.6 0.6 6.3e-20 71.3 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAM33313.1 - 5.7e-07 29.6 0.6 5.7e-07 29.6 0.6 1.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAM33313.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF2070 PF09843.9 GAM33313.1 - 1.2 7.3 9.1 23 3.1 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Cu-oxidase_2 PF07731.14 GAM33314.1 - 8.3e-35 119.5 2.1 1.5e-34 118.6 0.2 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAM33314.1 - 3.3e-18 65.8 4.2 6.8e-17 61.6 0.6 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 GAM33314.1 - 3.8e-15 56.4 0.0 5.1e-13 49.4 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase DUF1774 PF08611.10 GAM33315.1 - 4.4e-35 119.9 4.0 4.4e-35 119.9 4.0 2.6 3 1 0 3 3 3 1 Fungal protein of unknown function (DUF1774) BNR PF02012.20 GAM33316.1 - 0.021 14.7 0.5 0.12 12.4 0.5 2.4 1 0 0 1 1 1 0 BNR/Asp-box repeat Inositol_P PF00459.25 GAM33317.1 - 3.3e-38 131.8 0.0 5.3e-38 131.1 0.0 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family Peptidase_M28 PF04389.17 GAM33318.1 - 5.2e-27 94.8 0.1 8.7e-27 94.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 GAM33318.1 - 5.4e-05 23.0 0.0 0.00013 21.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 R3H-assoc PF13902.6 GAM33319.1 - 1.4e-23 83.8 10.7 2.6e-23 82.9 10.7 1.6 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 GAM33319.1 - 0.0005 20.0 0.0 0.029 14.4 0.0 2.5 2 0 0 2 2 2 1 R3H domain DDHD PF02862.17 GAM33319.1 - 0.029 14.5 0.1 0.053 13.7 0.1 1.4 1 0 0 1 1 1 0 DDHD domain Peptidase_M4_C PF02868.15 GAM33320.1 - 2.4e-41 141.4 0.0 1.1e-40 139.3 0.0 1.8 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 GAM33320.1 - 6.3e-28 98.1 0.0 1.1e-27 97.4 0.0 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain PLN_propep PF16485.5 GAM33320.1 - 6.7e-09 35.3 1.0 0.0028 17.3 0.1 2.5 2 0 0 2 2 2 2 Protealysin propeptide BetaGal_dom3 PF13363.6 GAM33321.1 - 0.099 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 DUF4449 PF14613.6 GAM33322.1 - 1.5e-62 210.5 2.9 1.5e-62 210.5 2.9 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) Prp18 PF02840.15 GAM33322.1 - 0.062 13.4 8.7 0.82 9.7 0.0 3.2 2 1 1 3 3 3 0 Prp18 domain Phi_1 PF04674.12 GAM33322.1 - 0.11 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region ILVD_EDD PF00920.21 GAM33323.1 - 2.8e-108 362.8 3.2 6e-101 338.6 3.1 3.0 1 1 1 2 2 2 2 Dehydratase family Pro-kuma_activ PF09286.11 GAM33324.1 - 3.5e-36 124.6 0.3 2.3e-35 121.9 0.1 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAM33324.1 - 5.6e-07 29.1 0.0 1.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Subtilase family PhnH PF05845.12 GAM33324.1 - 0.089 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) Acyl-CoA_dh_M PF02770.19 GAM33326.1 - 0.0044 17.2 0.0 0.0097 16.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAM33326.1 - 0.098 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Mcl1_mid PF12341.8 GAM33327.1 - 2.5e-104 348.8 0.0 1.2e-103 346.5 0.0 2.1 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 GAM33327.1 - 9.2e-20 70.7 0.0 0.00039 20.6 0.0 8.0 3 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAM33327.1 - 2.1e-16 60.0 4.6 8.4e-07 29.6 0.1 6.9 8 0 0 8 8 7 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 GAM33327.1 - 4.1e-08 32.7 0.0 2.3e-06 26.9 0.0 2.6 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 GAM33327.1 - 4.7e-06 26.6 0.5 0.0051 16.7 0.0 3.7 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAM33327.1 - 0.0036 16.3 0.3 5.2 5.9 0.3 3.7 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein MMS1_N PF10433.9 GAM33327.1 - 0.0074 15.0 0.0 0.02 13.5 0.0 1.7 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Cytochrom_D1 PF02239.16 GAM33327.1 - 0.078 11.5 0.5 0.98 7.9 0.1 2.3 2 1 1 3 3 3 0 Cytochrome D1 heme domain PD40 PF07676.12 GAM33327.1 - 0.1 12.6 0.8 47 4.1 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 GAM33327.1 - 0.12 10.3 0.1 0.76 7.7 0.1 2.1 1 1 0 1 1 1 0 IKI3 family DNA_pol_alpha_N PF12254.8 GAM33327.1 - 0.25 11.4 6.0 0.27 11.4 4.0 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal Lipase_GDSL_2 PF13472.6 GAM33328.1 - 2.4e-14 54.1 0.3 3.6e-14 53.6 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.18 GAM33328.1 - 9.1e-14 51.1 12.7 1.9e-13 50.1 12.7 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.22 GAM33328.1 - 1.3e-06 28.6 0.0 4e-05 23.7 0.0 2.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.16 GAM33329.1 - 1.4e-39 136.0 20.5 1.4e-39 136.0 20.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM33329.1 - 7.5e-07 28.4 7.8 7.5e-07 28.4 7.8 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAM33329.1 - 0.00013 20.6 1.6 0.00024 19.7 1.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1129 PF06570.11 GAM33329.1 - 0.011 15.3 2.5 6.2 6.3 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) LacY_symp PF01306.19 GAM33329.1 - 0.012 14.4 0.6 0.012 14.4 0.6 2.2 2 0 0 2 2 2 0 LacY proton/sugar symporter LysM PF01476.20 GAM33330.1 - 2.3e-05 24.3 0.0 1.2 9.3 0.0 3.4 3 0 0 3 3 3 3 LysM domain DUF3843 PF12954.7 GAM33330.1 - 0.066 12.2 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) Pectate_lyase_3 PF12708.7 GAM33331.1 - 3e-14 53.4 0.4 3e-14 53.4 0.4 1.8 2 0 0 2 2 2 1 Pectate lyase superfamily protein End_N_terminal PF12218.8 GAM33331.1 - 0.13 12.0 0.2 0.26 11.0 0.2 1.5 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase DUF3619 PF12279.8 GAM33332.1 - 0.023 15.0 3.1 0.023 15.0 3.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3619) MRP-S31 PF15433.6 GAM33332.1 - 1.5 8.4 15.3 2.6 7.7 15.3 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 PCRF PF03462.18 GAM33332.1 - 4.3 7.2 11.0 1.1 9.0 6.9 2.0 1 1 1 2 2 2 0 PCRF domain NPV_P10 PF05531.12 GAM33332.1 - 5 7.7 9.8 32 5.1 0.1 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.19 GAM33332.1 - 9 4.1 7.1 13 3.5 7.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NUDIX PF00293.28 GAM33333.1 - 5.5e-12 45.9 0.0 1.2e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain VTC PF09359.10 GAM33334.1 - 2.9e-90 302.4 0.4 5.2e-90 301.6 0.4 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 GAM33334.1 - 2.6e-11 43.8 3.2 2.6e-11 43.8 3.2 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF202) SPX PF03105.19 GAM33334.1 - 0.00013 22.1 22.1 0.0003 20.8 0.2 4.1 3 1 1 5 5 5 3 SPX domain UbiD PF01977.16 GAM33335.1 - 7e-106 354.5 0.0 8e-106 354.3 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FAD_binding_2 PF00890.24 GAM33336.1 - 9.6e-18 64.5 0.0 2.6e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAM33336.1 - 0.00051 19.7 0.0 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM33336.1 - 0.017 15.7 0.2 7.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM33336.1 - 0.044 13.0 0.0 0.083 12.1 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM33336.1 - 0.072 13.1 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAM33336.1 - 0.098 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Flavoprotein PF02441.19 GAM33337.1 - 6.3e-24 84.5 0.0 7.2e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein Oxidored_FMN PF00724.20 GAM33338.1 - 2.2e-55 188.3 0.8 1.5e-54 185.6 0.2 1.8 1 1 1 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.21 GAM33338.1 - 0.0037 17.1 0.0 0.0084 16.0 0.0 1.5 1 0 0 1 1 1 1 Tautomerase enzyme Abhydrolase_6 PF12697.7 GAM33339.1 - 2.6e-13 51.1 0.0 3.6e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM33339.1 - 1.3e-07 31.5 0.0 2.5e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM33339.1 - 0.0043 16.3 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 GAM33339.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 GAM33339.1 - 0.055 13.2 0.1 0.28 10.9 0.0 1.9 1 1 1 2 2 2 0 PGAP1-like protein Thioesterase PF00975.20 GAM33339.1 - 0.089 12.9 0.0 0.33 11.0 0.0 1.9 1 1 0 1 1 1 0 Thioesterase domain 7TM_GPCR_Srd PF10317.9 GAM33340.1 - 0.86 8.7 5.8 0.64 9.2 3.1 1.9 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd EVI2A PF05399.11 GAM33341.1 - 0.16 11.5 3.3 0.25 10.9 3.3 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Pacs-1 PF10254.9 GAM33341.1 - 0.29 10.1 2.7 0.39 9.6 2.7 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Sensor PF13796.6 GAM33341.1 - 0.34 10.9 6.4 5 7.1 6.4 2.2 1 1 0 1 1 1 0 Putative sensor 6PF2K PF01591.18 GAM33342.1 - 7e-70 234.8 0.0 9.6e-49 165.7 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAM33342.1 - 2.3e-31 109.0 0.1 1.2e-23 83.8 0.0 3.1 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAM33342.1 - 0.00014 22.1 0.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.10 GAM33342.1 - 0.034 13.6 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CcdA PF07362.12 GAM33342.1 - 0.14 12.6 1.6 0.51 10.8 0.3 2.4 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA DUF202 PF02656.15 GAM33343.1 - 0.0056 17.1 7.8 0.018 15.5 7.8 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF202) PQ-loop PF04193.14 GAM33345.1 - 2e-35 120.4 11.0 1.2e-17 63.5 2.5 2.5 2 0 0 2 2 2 2 PQ loop repeat GLEYA PF10528.9 GAM33345.1 - 1.3e-15 57.6 1.0 4e-15 56.0 1.0 1.8 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 GAM33345.1 - 0.0089 15.8 0.5 0.021 14.7 0.5 1.6 1 0 0 1 1 1 1 PA14 domain MtN3_slv PF03083.16 GAM33345.1 - 4.7 7.3 7.8 0.55 10.3 0.1 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange adh_short PF00106.25 GAM33346.1 - 2.8e-33 115.0 0.0 6.8e-33 113.8 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33346.1 - 6.1e-25 88.1 0.0 8.8e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM33346.1 - 0.00015 21.7 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF836 PF05768.14 GAM33346.1 - 0.086 13.3 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Glyco_hydro_7 PF00840.20 GAM33347.1 - 7.2e-196 651.1 13.2 9.5e-196 650.7 13.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 GAM33347.1 - 3.1e-14 52.6 14.3 3.1e-14 52.6 14.3 4.0 4 0 0 4 4 4 1 Fungal cellulose binding domain YtxH PF12732.7 GAM33348.1 - 3.9e-05 24.1 22.3 1.6 9.3 3.7 5.8 3 2 0 3 3 3 2 YtxH-like protein Apolipoprotein PF01442.18 GAM33348.1 - 0.0055 16.6 9.4 0.48 10.3 3.2 3.2 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain TerB PF05099.13 GAM33348.1 - 0.038 13.9 0.0 0.13 12.2 0.0 2.0 1 0 0 1 1 1 0 Tellurite resistance protein TerB Tmemb_14 PF03647.13 GAM33348.1 - 0.12 13.1 0.1 0.22 12.3 0.1 1.3 1 0 0 1 1 1 0 Transmembrane proteins 14C DUF883 PF05957.13 GAM33348.1 - 0.14 12.8 16.6 9.4 6.9 2.5 5.5 3 1 2 6 6 6 0 Bacterial protein of unknown function (DUF883) Het-C PF07217.11 GAM33348.1 - 0.17 10.4 5.5 0.052 12.1 0.3 2.1 1 1 1 2 2 2 0 Heterokaryon incompatibility protein Het-C DUF4404 PF14357.6 GAM33348.1 - 0.28 11.9 11.2 6.1 7.5 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DUF2937 PF11157.8 GAM33348.1 - 0.33 10.7 3.4 4.9 6.8 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) TFIIF_beta PF02270.15 GAM33348.1 - 1.2 9.3 3.9 6.5 7.0 0.1 3.1 3 0 0 3 3 3 0 TFIIF, beta subunit HTH domain CarD_CdnL_TRCF PF02559.16 GAM33348.1 - 1.3 9.7 10.1 4 8.2 1.2 4.6 1 1 3 4 4 4 0 CarD-like/TRCF domain WXG100 PF06013.12 GAM33348.1 - 4.6 7.5 9.5 9 6.6 0.1 4.7 4 2 0 4 4 4 0 Proteins of 100 residues with WXG FlgN PF05130.12 GAM33348.1 - 4.9 7.7 14.1 1.9 9.0 4.5 3.8 2 1 1 3 3 3 0 FlgN protein FKBP_N PF01346.18 GAM33348.1 - 5.1 8.1 13.6 0.28 12.2 0.6 3.9 3 1 1 4 4 4 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Amidase PF01425.21 GAM33349.1 - 2.4e-31 109.2 0.5 3.7e-31 108.6 0.5 1.2 1 0 0 1 1 1 1 Amidase Glyco_hydro_28 PF00295.17 GAM33350.1 - 2.7e-123 411.2 22.5 3.1e-123 411.0 22.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4957 PF16318.5 GAM33350.1 - 0.068 13.1 3.9 2.5 8.1 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4957) Rick_17kDa_Anti PF05433.15 GAM33351.1 - 6.3e-05 22.8 9.0 6.3e-05 22.8 9.0 2.5 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 GAM33351.1 - 0.0012 18.7 6.7 0.0012 18.7 6.7 2.4 2 0 0 2 2 2 1 Glycine zipper DUF533 PF04391.12 GAM33351.1 - 9.7 5.7 9.2 0.14 11.8 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF533) SH3_1 PF00018.28 GAM33352.1 - 8.4e-06 25.3 0.0 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAM33352.1 - 0.0072 16.2 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_16 PF18348.1 GAM33352.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Pkinase PF00069.25 GAM33353.1 - 1.3e-40 139.5 0.0 2e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM33353.1 - 1.7e-23 83.2 0.0 1.4e-19 70.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM33353.1 - 0.004 16.0 0.0 0.01 14.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAM33353.1 - 0.092 12.6 0.1 0.24 11.3 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L27A PF00828.19 GAM33354.1 - 4.9e-32 111.3 0.1 7.8e-32 110.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A PIG-Y PF15159.6 GAM33355.1 - 1.6e-21 77.0 8.2 2.6e-21 76.3 8.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y SelP_N PF04592.14 GAM33355.1 - 0.17 11.3 8.1 0.43 9.9 8.1 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1218 PF06749.12 GAM33355.1 - 1 9.9 3.9 29 5.3 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) GATase_4 PF13230.6 GAM33356.1 - 4.8e-14 51.9 0.0 5.4e-13 48.5 0.0 2.2 2 1 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 GAM33356.1 - 8.7e-08 32.4 0.0 1.5e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Dynamin_N PF00350.23 GAM33357.1 - 3e-45 154.3 0.0 5.8e-45 153.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 GAM33357.1 - 6.1e-17 61.8 0.0 1.2e-13 51.0 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 GAM33357.1 - 2.1e-05 24.5 0.0 0.00027 21.0 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 GAM33357.1 - 0.061 13.0 0.2 0.21 11.3 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 GAM33357.1 - 0.064 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Se-cys_synth_N PF12390.8 GAM33357.1 - 0.073 13.3 0.0 0.26 11.5 0.0 2.0 1 0 0 1 1 1 0 Selenocysteine synthase N terminal AAA_16 PF13191.6 GAM33357.1 - 0.089 13.2 0.3 0.43 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain Cyclin PF08613.11 GAM33358.1 - 6.7e-15 55.8 0.0 1.2e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAM33358.1 - 0.0051 16.6 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyr_redox_2 PF07992.14 GAM33359.1 - 3e-53 181.0 0.0 3.8e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM33359.1 - 6.7e-12 45.8 0.0 2e-10 41.1 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM33359.1 - 0.00098 18.5 0.1 0.63 9.2 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase COX14 PF14880.6 GAM33359.1 - 0.0061 16.4 1.2 0.021 14.7 1.2 1.9 1 0 0 1 1 1 1 Cytochrome oxidase c assembly UPF0193 PF05250.11 GAM33359.1 - 0.0066 16.3 0.3 0.015 15.1 0.3 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) NAD_binding_7 PF13241.6 GAM33359.1 - 1.8 9.0 4.1 21 5.6 0.0 3.6 3 1 0 3 3 3 0 Putative NAD(P)-binding WBS_methylT PF12589.8 GAM33360.1 - 7.9 7.3 7.0 83 4.0 0.0 4.0 4 0 0 4 4 4 0 Methyltransferase involved in Williams-Beuren syndrome GFA PF04828.14 GAM33361.1 - 1.2e-12 48.0 0.2 9.6e-06 25.9 0.0 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.16 GAM33361.1 - 0.022 15.0 0.6 0.065 13.5 0.0 1.9 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Cytochrom_NNT PF03264.14 GAM33361.1 - 0.063 13.0 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Paired_CXXCH_1 PF09699.10 GAM33361.1 - 0.099 12.4 1.0 0.82 9.5 0.1 2.2 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) GTP_EFTU PF00009.27 GAM33362.1 - 5.1e-57 192.5 0.1 6.8e-57 192.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAM33362.1 - 2.2e-21 76.2 0.0 5.1e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAM33362.1 - 2.2e-18 66.4 0.8 5.7e-18 65.1 0.8 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAM33362.1 - 1.3e-05 25.2 0.1 3.1e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM33362.1 - 0.0013 18.7 0.2 0.0054 16.6 0.1 2.0 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 GAM33362.1 - 0.024 14.2 0.5 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 GAM33362.1 - 0.035 13.9 0.2 6.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IF3_N PF05198.16 GAM33363.1 - 3.8e-11 43.1 0.1 6.6e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 GAM33363.1 - 5.6e-07 29.4 0.2 9.4e-07 28.7 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 GAM33363.1 - 1.1e-05 25.1 0.4 1.9e-05 24.4 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial translation initiation factor DUF2175 PF09943.9 GAM33363.1 - 0.035 14.4 1.4 0.11 12.8 0.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) GDA1_CD39 PF01150.17 GAM33364.1 - 3.7e-100 335.6 0.0 4.9e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4598 PF15370.6 GAM33365.1 - 1e-27 96.8 6.0 1e-27 96.8 6.0 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) DUF4551 PF15087.6 GAM33365.1 - 3.1 6.5 5.1 4.7 5.9 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ank_2 PF12796.7 GAM33366.1 - 1.3e-24 86.6 0.1 1.7e-15 57.3 0.0 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM33366.1 - 4.6e-16 57.3 0.4 0.024 15.2 0.0 6.2 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 GAM33366.1 - 2.4e-15 56.2 0.0 0.003 17.9 0.0 5.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 GAM33366.1 - 1.7e-13 50.5 0.2 3.7e-05 23.9 0.0 5.5 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM33366.1 - 2.3e-12 47.2 0.0 8.3e-07 29.4 0.0 3.7 1 1 1 3 3 3 2 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 GAM33366.1 - 1.9e-09 37.2 0.3 6.8e-09 35.3 0.3 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily IF4E PF01652.18 GAM33368.1 - 4.5e-23 81.8 0.2 6.5e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CHU_C PF13585.6 GAM33368.1 - 0.073 13.1 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of CHU protein family 2Fe-2S_thioredx PF01257.19 GAM33368.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin MFS_1 PF07690.16 GAM33369.1 - 3e-46 158.0 58.0 7.4e-45 153.4 56.5 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM33369.1 - 1.4e-21 76.6 13.0 2.5e-21 75.8 13.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM33369.1 - 3.3e-12 46.0 10.6 3.3e-12 46.0 10.6 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter Zn_clus PF00172.18 GAM33370.1 - 4.4e-06 26.7 9.0 6.8e-06 26.1 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COMPASS-Shg1 PF05205.12 GAM33371.1 - 1.6e-27 96.2 0.4 1.6e-27 96.2 0.4 2.9 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 Cation_efflux PF01545.21 GAM33373.1 - 3.9e-15 56.1 11.1 5.2e-15 55.7 11.1 1.1 1 0 0 1 1 1 1 Cation efflux family zf-RING_2 PF13639.6 GAM33374.1 - 3e-08 33.9 6.9 5.8e-08 32.9 2.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 GAM33374.1 - 2e-07 31.2 5.0 6e-07 29.7 5.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAM33374.1 - 7.2e-07 28.9 6.9 2.6e-06 27.2 2.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM33374.1 - 1.6e-06 27.9 2.0 4.1e-06 26.6 2.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAM33374.1 - 1.7e-06 27.8 1.4 2.9e-06 27.1 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM33374.1 - 0.00015 21.6 1.5 0.00015 21.6 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM33374.1 - 0.00018 21.3 1.1 0.00018 21.3 1.1 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 GAM33374.1 - 0.00018 21.1 9.5 0.0031 17.2 0.2 3.3 3 0 0 3 3 3 2 RING-like zinc finger zf-RING_UBOX PF13445.6 GAM33374.1 - 0.001 19.1 5.4 0.0015 18.6 1.4 2.9 1 1 1 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 GAM33374.1 - 0.005 16.4 0.6 0.005 16.4 0.6 1.7 2 0 0 2 2 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GAM33374.1 - 0.0068 16.4 0.7 0.015 15.3 0.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.8 GAM33374.1 - 0.055 11.3 0.3 0.081 10.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) PQ-loop PF04193.14 GAM33374.1 - 0.38 10.5 4.1 0.31 10.8 0.6 2.5 2 0 0 2 2 2 0 PQ loop repeat RINGv PF12906.7 GAM33374.1 - 7.2 6.8 6.7 0.7 10.1 1.8 1.9 2 0 0 2 2 2 0 RING-variant domain GCV_H PF01597.19 GAM33375.1 - 3.1e-39 133.6 1.7 3.6e-39 133.4 1.7 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 GAM33375.1 - 0.057 13.3 0.5 0.44 10.4 0.2 2.3 1 1 1 2 2 2 0 Biotin-requiring enzyme Ribosomal_S6 PF01250.17 GAM33376.1 - 3.8e-20 72.0 0.0 4.9e-18 65.2 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein S6 ADH_zinc_N PF00107.26 GAM33378.1 - 0.0069 16.4 0.2 0.014 15.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CMD PF02627.20 GAM33379.1 - 8.8e-16 57.7 0.1 1.1e-15 57.4 0.1 1.1 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family MFS_1 PF07690.16 GAM33380.1 - 2.8e-40 138.3 27.8 3.4e-40 138.1 27.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 GAM33380.1 - 0.0013 17.1 8.1 0.0013 17.1 8.1 2.0 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family APH PF01636.23 GAM33381.1 - 9e-10 38.9 0.0 2.7e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Chs7 PF12271.8 GAM33382.1 - 2.5e-124 414.3 11.8 2.9e-124 414.1 11.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Acetyltransf_1 PF00583.25 GAM33383.1 - 1.8e-09 37.8 0.0 4.6e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM33383.1 - 8.3e-09 35.5 0.0 1.9e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM33383.1 - 3e-08 33.9 0.0 1.3e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM33383.1 - 0.00015 21.9 0.0 0.0078 16.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM33383.1 - 0.00064 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 GAM33383.1 - 0.0013 18.6 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein PGAP1 PF07819.13 GAM33383.1 - 0.0025 17.5 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 GAM33383.1 - 0.0073 15.5 0.1 0.016 14.4 0.0 1.5 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase CwsA PF10814.8 GAM33383.1 - 0.05 13.8 2.1 0.11 12.7 2.1 1.5 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Hydrolase_4 PF12146.8 GAM33383.1 - 0.1 11.8 0.1 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 GAM33383.1 - 0.18 11.6 0.3 5.2 6.8 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Sporozoite_P67 PF05642.11 GAM33383.1 - 0.57 8.2 1.7 0.8 7.7 1.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Abhydrolase_6 PF12697.7 GAM33383.1 - 1.8 9.1 11.5 6.9 7.2 10.6 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Arrestin_C PF02752.22 GAM33384.1 - 3.1e-20 73.0 0.1 2.2e-18 67.0 0.0 3.0 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAM33384.1 - 2.2e-10 40.7 0.0 2.6e-05 24.3 0.0 2.5 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Acetyltransf_4 PF13420.7 GAM33386.1 - 2.5e-06 27.7 0.0 2.3e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM33386.1 - 4.7e-05 23.7 0.0 7.9e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM33386.1 - 0.0001 22.5 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 GAM33386.1 - 0.017 15.8 0.0 0.022 15.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM33386.1 - 0.032 14.2 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HicA_toxin PF07927.12 GAM33386.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, Med21 PF11221.8 GAM33387.1 - 0.92 9.8 2.6 1.6 8.9 2.5 1.5 1 1 0 1 1 1 0 Subunit 21 of Mediator complex CDC48_2 PF02933.17 GAM33387.1 - 4.2 7.2 6.5 5.8 6.8 0.1 2.5 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 RRM_1 PF00076.22 GAM33388.1 - 4.8e-59 196.1 0.0 7.6e-21 73.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM33388.1 - 2.4e-07 30.5 0.0 0.0046 16.8 0.0 2.9 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 GAM33388.1 - 4e-07 29.7 0.0 0.00037 20.1 0.0 2.8 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM33388.1 - 0.00079 19.5 0.1 0.99 9.6 0.0 3.3 3 1 0 3 3 3 2 RNA recognition motif RRM_8 PF11835.8 GAM33388.1 - 0.00089 19.4 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 2 RRM-like domain Cas_Cas2CT1978 PF09707.10 GAM33388.1 - 0.003 17.6 0.0 0.49 10.5 0.0 2.5 2 0 0 2 2 2 1 CRISPR-associated protein (Cas_Cas2CT1978) Nup35_RRM_2 PF14605.6 GAM33388.1 - 0.0067 16.4 0.1 2.9 8.0 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 GAM33388.1 - 0.081 13.0 0.1 3 7.9 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif RNA_bind PF08675.11 GAM33388.1 - 0.092 12.8 0.1 12 6.0 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain MFS_1 PF07690.16 GAM33389.1 - 2.7e-41 141.7 43.0 2.7e-41 141.7 43.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM33389.1 - 2.4e-12 46.5 31.2 7.8e-12 44.8 1.6 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter DUF3377 PF11857.8 GAM33389.1 - 0.034 14.1 0.1 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) CrgA PF06781.12 GAM33389.1 - 0.3 11.2 3.4 25 5.0 0.5 3.8 3 0 0 3 3 3 0 Cell division protein CrgA Zn_clus PF00172.18 GAM33390.1 - 3.2e-06 27.2 10.3 6.4e-06 26.2 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM33390.1 - 0.044 12.8 0.2 0.23 10.5 0.2 2.1 1 1 0 1 1 1 0 Fungal specific transcription factor domain HRI1 PF16815.5 GAM33391.1 - 6.2e-33 114.4 0.3 7.3e-33 114.2 0.3 1.0 1 0 0 1 1 1 1 Protein HRI1 Fungal_trans_2 PF11951.8 GAM33392.1 - 5.9e-49 166.9 2.5 7.7e-49 166.5 2.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM33392.1 - 2.8e-06 27.3 12.3 2.8e-06 27.3 12.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 GAM33393.1 - 4.6e-65 219.9 0.0 5.9e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM33393.1 - 8.3e-34 117.2 0.0 4.4e-33 114.8 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase Thi4 PF01946.17 GAM33393.1 - 5.3e-07 29.1 0.1 0.00016 21.0 0.1 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 GAM33393.1 - 9.4e-07 28.7 0.3 0.00038 20.1 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM33393.1 - 6.2e-06 25.6 0.0 0.0011 18.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAM33393.1 - 1.1e-05 25.5 0.0 2.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAM33393.1 - 0.00016 20.8 0.1 0.00034 19.8 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 GAM33393.1 - 0.00093 19.7 0.1 0.35 11.5 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM33393.1 - 0.0015 17.8 0.1 0.26 10.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM33393.1 - 0.011 15.1 0.1 1.1 8.4 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM33393.1 - 0.031 13.0 0.2 0.12 11.0 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 GAM33393.1 - 0.21 11.5 0.6 0.52 10.3 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_4 PF07993.12 GAM33394.1 - 4.6e-14 52.2 0.0 7.5e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 GAM33394.1 - 0.0069 16.7 0.1 0.045 14.1 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 GAM33394.1 - 0.0091 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.23 GAM33395.1 - 1.1e-18 67.3 1.6 1.8e-18 66.6 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM33395.1 - 0.012 15.7 0.1 0.026 14.6 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like ketoacyl-synt PF00109.26 GAM33396.1 - 7.7e-79 264.8 0.0 1.5e-78 263.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 GAM33396.1 - 5.9e-40 137.5 7.3 3.4e-25 89.2 0.4 3.3 2 1 1 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 GAM33396.1 - 1.6e-36 126.4 0.2 5.8e-36 124.6 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM33396.1 - 2e-28 98.8 1.0 4.3e-28 97.7 1.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 GAM33396.1 - 5.1e-20 72.6 0.0 6.2e-19 69.0 0.0 2.5 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 GAM33396.1 - 1.2e-13 51.0 0.0 2.6e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 GAM33396.1 - 3.3e-05 23.4 0.0 0.00056 19.4 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 GAM33396.1 - 0.0014 19.0 0.0 0.0058 17.1 0.0 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 GAM33396.1 - 0.0029 17.9 0.2 0.014 15.7 0.2 2.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 GAM33396.1 - 0.0057 17.3 0.1 0.32 11.6 0.0 3.0 2 1 1 3 3 3 1 Alpha/beta hydrolase family DUF3446 PF11928.8 GAM33396.1 - 4.8 7.6 10.0 0.72 10.2 4.3 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain adh_short PF00106.25 GAM33397.1 - 6.8e-32 110.5 0.0 8.5e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33397.1 - 4.3e-20 72.3 0.0 5.3e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM33397.1 - 1.6e-06 28.1 0.0 4.1e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 GAM33397.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 GAM33397.1 - 0.022 14.3 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.23 GAM33399.1 - 7.5e-19 67.8 0.3 1.3e-18 67.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.19 GAM33400.1 - 1e-49 169.5 0.0 1.3e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM33400.1 - 2e-26 93.3 0.1 4.1e-26 92.2 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 GAM33400.1 - 1.4e-07 31.1 0.9 0.0017 17.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM33400.1 - 4.9e-07 29.6 0.6 3.1e-05 23.7 1.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM33400.1 - 2.6e-06 26.8 3.1 0.00016 20.9 1.7 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAM33400.1 - 0.00073 18.9 0.1 0.0016 17.8 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM33400.1 - 0.0008 19.6 2.0 0.0029 17.8 2.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAM33400.1 - 0.0024 17.0 1.0 0.004 16.2 0.2 1.8 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.17 GAM33400.1 - 0.047 12.9 1.8 0.082 12.1 0.4 1.9 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 GAM33400.1 - 0.18 10.5 0.4 0.29 9.8 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 GAM33400.1 - 0.19 10.6 0.3 0.27 10.0 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 GAM33400.1 - 0.59 10.7 3.9 1.1 9.8 1.4 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_2 PF00891.18 GAM33401.1 - 2e-25 89.3 0.0 3.1e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 GAM33401.1 - 0.00015 22.5 0.0 0.00094 19.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM33401.1 - 0.0059 17.3 0.0 0.019 15.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 GAM33401.1 - 0.021 14.3 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain DUF938 PF06080.12 GAM33401.1 - 0.031 14.0 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_23 PF13489.6 GAM33401.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 GAM33401.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase NAS PF03059.16 GAM33401.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein FAD_binding_3 PF01494.19 GAM33402.1 - 7.8e-13 48.4 0.1 2.1e-05 24.0 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 GAM33402.1 - 1.7e-05 24.9 0.1 4.3e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM33402.1 - 0.0014 17.9 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GAM33402.1 - 0.0027 18.0 0.1 0.019 15.2 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox PF00070.27 GAM33402.1 - 0.0033 18.0 0.0 0.0064 17.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM33402.1 - 0.0057 16.3 0.1 0.01 15.4 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAM33402.1 - 0.018 14.3 0.0 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 GAM33402.1 - 0.042 13.5 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.24 GAM33402.1 - 0.062 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 GAM33402.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FMO-like PF00743.19 GAM33403.1 - 7.5e-14 51.0 0.4 5.6e-11 41.6 0.1 2.9 2 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAM33403.1 - 9.2e-07 28.4 0.0 4e-05 23.0 0.0 2.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM33403.1 - 1.2e-06 27.9 0.0 6.7e-05 22.2 0.0 3.1 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAM33403.1 - 2.8e-05 23.5 0.0 0.00028 20.3 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAM33403.1 - 0.03 13.6 0.0 3.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM33403.1 - 0.032 14.4 0.0 0.079 13.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain EVE PF01878.18 GAM33403.1 - 0.034 14.1 0.4 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 EVE domain Shikimate_DH PF01488.20 GAM33403.1 - 0.098 12.7 0.0 17 5.4 0.0 3.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 GAM33403.1 - 0.11 13.1 0.6 10 6.7 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RHD3 PF05879.12 GAM33404.1 - 0 1068.4 0.0 0 1068.2 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 GAM33404.1 - 1.1e-07 31.4 0.2 1.9e-07 30.6 0.2 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 GAM33404.1 - 5.5e-06 26.5 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAM33404.1 - 0.00016 21.7 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 GAM33404.1 - 0.0056 16.9 0.4 0.019 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 GAM33404.1 - 0.0095 15.2 0.0 0.043 13.1 0.0 2.0 2 0 0 2 2 2 1 Septin V-SNARE PF05008.15 GAM33404.1 - 0.34 11.3 3.5 0.22 11.9 0.5 2.3 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus p450 PF00067.22 GAM33405.1 - 1.1e-42 146.4 0.0 1.9e-42 145.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 GAM33406.1 - 1.1e-29 103.5 25.2 2.7e-26 92.3 13.9 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM33406.1 - 0.003 16.5 25.7 0.059 12.2 25.7 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 GAM33406.1 - 0.02 13.2 5.0 0.21 9.8 1.5 2.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PUCC PF03209.15 GAM33406.1 - 0.22 10.5 13.2 0.89 8.5 6.4 2.4 2 1 0 2 2 2 0 PUCC protein Vma12 PF11712.8 GAM33406.1 - 2 8.5 3.5 0.92 9.6 0.1 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Fungal_trans_2 PF11951.8 GAM33407.1 - 1.5e-34 119.5 0.0 1.7e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyclase PF04199.13 GAM33408.1 - 3.6e-11 43.5 0.0 8.6e-11 42.2 0.0 1.4 1 1 1 2 2 2 1 Putative cyclase Cupin_3 PF05899.12 GAM33408.1 - 0.014 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF5490 PF17593.2 GAM33408.1 - 0.068 13.2 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5490) HMG_box_2 PF09011.10 GAM33408.1 - 0.085 13.5 0.2 0.22 12.1 0.1 1.7 2 0 0 2 2 2 0 HMG-box domain Dynamin_M PF01031.20 GAM33409.1 - 1.2e-19 70.7 0.1 2.1e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 GAM33409.1 - 0.017 15.2 0.8 0.13 12.3 0.0 2.7 3 1 0 3 3 3 0 Dynamin family RelA_SpoT PF04607.17 GAM33409.1 - 0.074 13.3 1.0 0.37 11.1 0.3 2.5 3 0 0 3 3 3 0 Region found in RelA / SpoT proteins DUF3825 PF12873.7 GAM33409.1 - 0.09 12.2 0.2 0.27 10.7 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) Fungal_trans PF04082.18 GAM33411.1 - 3.8e-05 22.9 0.2 0.0013 17.8 0.2 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Glyco_hydro_3_C PF01915.22 GAM33412.1 - 1.7e-58 198.0 0.0 2.9e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAM33412.1 - 4.6e-48 164.2 0.0 7.4e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM33412.1 - 1.8e-23 82.4 0.1 4e-22 78.1 0.2 2.8 3 0 0 3 3 3 1 Fibronectin type III-like domain PA14 PF07691.12 GAM33412.1 - 1.3e-14 54.2 0.0 2.5e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain C1q PF00386.21 GAM33412.1 - 0.19 12.0 0.0 0.52 10.5 0.0 1.7 1 0 0 1 1 1 0 C1q domain Sugar_tr PF00083.24 GAM33413.1 - 9.8e-78 262.0 24.7 1.2e-77 261.7 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM33413.1 - 2.5e-22 79.3 39.1 5.5e-20 71.6 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M24 PF00557.24 GAM33414.1 - 9.6e-18 64.6 0.0 1.8e-17 63.7 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 Mu-like_gpT PF10124.9 GAM33414.1 - 0.13 11.5 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Mu-like prophage major head subunit gpT Zn_clus PF00172.18 GAM33415.1 - 3.1e-07 30.4 9.8 6.3e-07 29.4 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1485 PF07364.12 GAM33415.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M81 4HBT_2 PF13279.6 GAM33416.1 - 1.1e-05 25.9 0.0 1.8e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily HIG_1_N PF04588.13 GAM33417.1 - 3.3e-07 30.4 0.1 7e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Med26 PF08711.11 GAM33418.1 - 1.7e-08 34.4 0.0 3.7e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Tox-SHH PF15652.6 GAM33418.1 - 2.9 8.9 5.2 1.2 10.2 1.4 2.3 2 1 0 2 2 2 0 HNH/Endo VII superfamily toxin with a SHH signature Nup54 PF13874.6 GAM33419.1 - 1.8e-40 138.3 0.0 1.8e-40 138.3 0.0 2.5 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 GAM33419.1 - 1.3e-24 86.8 75.6 6.6e-14 52.5 32.3 3.3 2 1 1 3 3 3 2 Nucleoporin FG repeat region Nup54_57_C PF18570.1 GAM33419.1 - 2.4e-09 36.6 0.2 4.5e-09 35.7 0.2 1.5 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Prefoldin PF02996.17 GAM33419.1 - 2.6 8.0 7.6 0.54 10.2 1.1 2.6 3 0 0 3 3 3 0 Prefoldin subunit Suf PF05843.14 GAM33419.1 - 3.2 7.6 5.4 5.8 6.8 5.4 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) 4HBT PF03061.22 GAM33420.1 - 2.3e-08 34.3 0.0 4.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Hydant_A_N PF05378.13 GAM33420.1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.16 GAM33421.1 - 1.1e-34 119.9 33.3 1.1e-34 119.9 33.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM33423.1 - 9.1e-10 38.0 0.1 1.6e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 GAM33424.1 - 3.8e-71 240.2 0.0 5.3e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Methyltransf_2 PF00891.18 GAM33424.1 - 9.4e-25 87.1 0.0 3.3e-24 85.4 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_31 PF13847.6 GAM33424.1 - 2.4e-06 27.4 0.0 5.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM33424.1 - 3.5e-06 27.6 0.0 1.4e-05 25.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM33424.1 - 3.1e-05 24.7 0.0 9.5e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM33424.1 - 0.00032 20.6 0.0 0.00076 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM33424.1 - 0.0011 19.6 0.0 0.0034 18.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM33424.1 - 0.002 17.7 0.0 0.0048 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain NAD_binding_8 PF13450.6 GAM33424.1 - 0.0038 17.4 0.1 0.012 15.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain CheR PF01739.18 GAM33424.1 - 0.0079 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.9 GAM33424.1 - 0.027 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Pyr_redox_3 PF13738.6 GAM33424.1 - 0.042 13.1 0.1 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM33424.1 - 0.072 13.7 0.0 1.6 9.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAM33425.1 - 3.6e-13 49.5 0.7 1.1e-09 38.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAM33425.1 - 2.7e-05 23.6 0.2 7e-05 22.2 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM33425.1 - 5.1e-05 23.0 2.2 0.072 12.7 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM33425.1 - 0.0047 16.1 0.8 0.0074 15.4 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM33425.1 - 0.013 15.7 2.2 0.032 14.4 2.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAM33425.1 - 0.12 11.2 0.9 0.51 9.1 0.6 1.9 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 GAM33425.1 - 0.26 10.3 0.9 0.38 9.8 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 GAM33425.1 - 0.51 10.9 2.6 2.9 8.5 1.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 GAM33426.1 - 7.6e-19 67.8 61.4 6.9e-15 54.8 41.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 GAM33427.1 - 7.4e-07 29.2 6.9 7.4e-07 29.2 6.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cpn60_TCP1 PF00118.24 GAM33428.1 - 1.4e-85 287.8 13.2 4.9e-85 286.0 13.2 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family ATP-synt_Eps PF04627.13 GAM33430.1 - 1.3e-23 82.7 3.6 1.9e-23 82.1 3.6 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.13 GAM33431.1 - 1e-59 200.8 0.1 2.4e-56 189.9 0.0 2.3 1 1 1 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase E1_4HB PF16191.5 GAM33431.1 - 0.063 13.5 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Fungal_trans PF04082.18 GAM33432.1 - 2.2e-06 26.9 0.4 3.4e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain GST_C_6 PF17171.4 GAM33432.1 - 0.18 11.6 0.2 8.7 6.2 0.0 3.4 3 1 1 4 4 4 0 Glutathione S-transferase, C-terminal domain WD40 PF00400.32 GAM33433.1 - 1.2e-103 336.1 29.5 2.2e-09 37.8 0.0 12.9 12 0 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM33433.1 - 8e-34 115.8 0.0 0.0048 17.2 0.0 11.3 2 2 9 11 11 11 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM33433.1 - 6.4e-28 97.7 14.7 0.012 14.6 0.0 11.2 2 2 6 11 11 11 10 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 GAM33433.1 - 8e-21 74.7 0.0 1.4e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 GAM33433.1 - 3.8e-13 49.0 6.2 5.3 7.1 0.0 10.2 10 0 0 10 10 10 3 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 GAM33433.1 - 9.6e-07 28.4 1.6 19 5.0 0.0 7.7 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Nup160 PF11715.8 GAM33433.1 - 1e-05 24.5 10.7 4.3 5.9 0.0 7.4 4 3 5 9 9 9 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 GAM33433.1 - 0.00023 20.6 4.3 48 3.1 0.0 7.3 3 2 6 9 9 9 0 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 GAM33433.1 - 0.00078 19.1 10.7 0.069 12.7 0.3 4.1 1 1 3 4 4 4 2 PQQ-like domain PNP_UDP_1 PF01048.20 GAM33433.1 - 0.0014 17.9 0.1 0.0068 15.7 0.1 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily WD40_like PF17005.5 GAM33433.1 - 0.0015 17.9 0.0 1.1 8.5 0.0 3.1 3 0 0 3 3 3 1 WD40-like domain Gmad1 PF10647.9 GAM33433.1 - 0.002 18.0 11.3 0.15 11.8 0.2 6.3 3 1 4 7 7 7 1 Lipoprotein LpqB beta-propeller domain AAA_19 PF13245.6 GAM33433.1 - 0.0033 17.8 0.0 0.0077 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAM33433.1 - 0.026 14.9 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 GAM33433.1 - 0.087 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 GAM33433.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 GAM33433.1 - 0.19 10.9 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Abhydrolase_3 PF07859.13 GAM33434.1 - 1.5e-13 51.1 0.0 5e-08 33.0 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM33434.1 - 2.2e-10 40.4 0.0 1.1e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GAM33434.1 - 2.5e-06 27.3 0.0 2.6e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 GAM33434.1 - 1.7e-05 24.7 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 GAM33434.1 - 6.7e-05 22.7 0.0 0.00047 19.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 GAM33434.1 - 0.00019 21.1 0.0 0.009 15.7 0.0 2.2 2 0 0 2 2 2 1 Putative esterase DLH PF01738.18 GAM33434.1 - 0.00043 19.9 0.0 0.068 12.7 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 GAM33434.1 - 0.0005 19.4 0.0 0.51 9.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 GAM33434.1 - 0.00053 19.0 0.0 0.00077 18.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.28 GAM33434.1 - 0.0021 17.0 0.1 0.0051 15.7 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family LIP PF03583.14 GAM33434.1 - 0.094 12.0 0.0 0.62 9.3 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase 3HBOH PF10605.9 GAM33434.1 - 0.19 9.9 0.0 0.24 9.6 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) BAAT_C PF08840.11 GAM33434.1 - 0.23 11.4 0.0 0.64 9.9 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Fungal_trans PF04082.18 GAM33435.1 - 1e-06 28.0 2.4 2.1e-06 27.0 2.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 GAM33436.1 - 7.4e-65 219.5 0.0 9.7e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.23 GAM33436.1 - 7.1e-07 29.4 0.0 1.7e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM33436.1 - 0.0042 16.7 0.7 0.009 15.6 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 GAM33436.1 - 0.0075 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase CAP PF00188.26 GAM33437.1 - 1.5e-16 61.4 1.0 2.3e-16 60.8 1.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Thioredox_DsbH PF03190.15 GAM33438.1 - 1.5e-70 236.4 0.1 3.1e-70 235.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 GAM33438.1 - 9.7e-06 25.7 0.0 2.4e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_9 PF00759.19 GAM33438.1 - 0.00013 21.5 0.1 0.00028 20.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_88 PF07470.13 GAM33438.1 - 0.0028 16.8 0.0 0.8 8.7 0.1 3.1 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 GAM33438.1 - 0.0088 15.6 0.1 0.04 13.4 0.1 2.0 3 0 0 3 3 3 1 Glycosyl hydrolase family 76 Sigma70_r4 PF04545.16 GAM33438.1 - 0.11 12.0 0.1 0.28 10.7 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 WD40 PF00400.32 GAM33439.1 - 8.4e-24 83.4 5.9 6e-07 30.1 0.3 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM33439.1 - 2.1e-05 24.7 0.1 0.12 12.7 0.0 3.8 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Reg_prop PF07494.11 GAM33439.1 - 0.014 15.5 0.0 1.2 9.6 0.0 3.2 2 0 0 2 2 2 0 Two component regulator propeller Nup160 PF11715.8 GAM33439.1 - 0.03 13.0 0.0 0.65 8.6 0.0 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Sigma70_r1_2 PF00140.20 GAM33439.1 - 0.1 12.7 1.7 0.22 11.5 1.7 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 PQQ_3 PF13570.6 GAM33439.1 - 0.29 11.7 1.4 1.6 9.3 0.0 2.9 4 0 0 4 4 4 0 PQQ-like domain LSM14 PF12701.7 GAM33440.1 - 3.6e-28 97.5 0.1 5.8e-28 96.8 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 GAM33440.1 - 3.2e-19 69.7 5.3 7.2e-19 68.6 5.3 1.6 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.6 GAM33440.1 - 2e-06 27.8 0.0 3.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 GAM33440.1 - 0.23 11.2 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 LSM domain GRP PF07172.11 GAM33440.1 - 0.4 11.4 19.3 0.52 11.0 14.1 2.5 2 0 0 2 2 2 0 Glycine rich protein family Oxidored_FMN PF00724.20 GAM33441.1 - 4.4e-75 253.1 0.0 1.3e-74 251.6 0.0 1.6 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 GAM33441.1 - 0.0025 17.3 0.0 0.12 11.8 0.0 2.2 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel GLTSCR1 PF15249.6 GAM33441.1 - 0.2 12.1 0.0 0.41 11.1 0.0 1.4 1 0 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein ACBP PF00887.19 GAM33442.1 - 1.4e-21 76.5 0.0 2.7e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein CDC45 PF02724.14 GAM33442.1 - 3.4e-05 22.4 5.0 5e-05 21.8 5.0 1.2 1 0 0 1 1 1 1 CDC45-like protein SIL1 PF16782.5 GAM33442.1 - 0.0095 15.2 4.1 0.017 14.3 0.8 2.3 1 1 1 2 2 2 1 Nucleotide exchange factor SIL1 RRN3 PF05327.11 GAM33442.1 - 0.092 11.3 3.6 0.13 10.8 3.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 LMBR1 PF04791.16 GAM33442.1 - 0.15 10.9 2.0 0.17 10.7 2.0 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein BUD22 PF09073.10 GAM33442.1 - 0.24 10.7 13.2 0.34 10.2 13.2 1.3 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 GAM33442.1 - 1.3 8.5 13.2 0.92 9.0 11.6 1.4 1 1 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 GAM33442.1 - 3.9 6.7 8.9 6 6.1 8.9 1.3 1 0 0 1 1 1 0 NOA36 protein SAPS PF04499.15 GAM33443.1 - 0.12 11.2 7.6 0.15 10.8 7.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 GAM33443.1 - 3 7.2 28.5 4 6.8 28.5 1.1 1 0 0 1 1 1 0 SDA1 DUF4710 PF15828.5 GAM33443.1 - 9 6.5 8.0 0.28 11.3 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) GST_N_3 PF13417.6 GAM33444.1 - 4.5e-17 62.2 0.1 9e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM33444.1 - 7e-17 61.5 0.1 1.5e-16 60.4 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAM33444.1 - 1.7e-15 57.1 0.0 3.2e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GAM33444.1 - 2.6e-05 24.3 0.0 4.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_5 PF16865.5 GAM33444.1 - 0.0068 17.0 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NACHT_N PF17100.5 GAM33445.1 - 1.6e-68 230.9 0.1 1.6e-68 230.9 0.1 2.5 3 0 0 3 3 3 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 GAM33445.1 - 8.7e-46 154.4 5.0 3.9e-12 46.6 0.1 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM33445.1 - 1.1e-28 99.2 0.1 5.4e-06 26.9 0.0 5.5 2 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 GAM33445.1 - 1.4e-28 98.1 0.0 9.6e-06 25.8 0.0 7.1 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 GAM33445.1 - 4.3e-27 93.8 0.4 7.1e-10 38.9 0.1 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM33445.1 - 7.8e-24 81.2 0.5 5.8e-05 23.2 0.0 8.3 9 0 0 9 9 9 4 Ankyrin repeat NACHT PF05729.12 GAM33445.1 - 2.4e-05 24.3 0.0 6.4e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GAM33445.1 - 0.00057 20.2 0.1 0.0033 17.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM33445.1 - 0.0072 16.7 0.3 0.051 13.9 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 GAM33445.1 - 0.1 12.6 0.6 2 8.5 0.0 3.3 3 1 0 3 3 3 0 AAA domain COX4 PF02936.14 GAM33446.1 - 6.5e-43 146.1 1.0 1e-42 145.4 1.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Cofilin_ADF PF00241.20 GAM33446.1 - 4.8e-33 113.5 0.1 8e-33 112.8 0.1 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3106 PF11304.8 GAM33446.1 - 0.56 10.7 5.6 0.16 12.5 1.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) ATP-synt_ab PF00006.25 GAM33447.1 - 8.7e-62 208.5 0.0 1.5e-61 207.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GAM33447.1 - 5.4e-24 84.5 0.2 2.4e-23 82.4 0.1 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 GAM33447.1 - 0.0041 16.5 0.2 0.0069 15.8 0.2 1.4 1 0 0 1 1 1 1 KaiC AAA PF00004.29 GAM33447.1 - 0.008 16.6 0.1 0.82 10.1 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 GAM33447.1 - 0.017 14.3 0.3 0.11 11.7 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 GAM33447.1 - 0.019 14.9 0.5 0.043 13.7 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase T3SS_ATPase_C PF18269.1 GAM33447.1 - 0.031 14.1 0.9 0.13 12.2 0.9 1.9 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA_19 PF13245.6 GAM33447.1 - 0.039 14.3 1.1 0.49 10.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAM33447.1 - 0.041 13.8 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 GAM33447.1 - 0.056 13.4 0.2 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 GAM33447.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 GAM33447.1 - 0.11 12.8 0.1 0.49 10.8 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain 3Beta_HSD PF01073.19 GAM33448.1 - 5.2e-40 137.2 0.0 6.8e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM33448.1 - 2.8e-18 66.3 0.0 5.7e-18 65.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM33448.1 - 1.4e-12 47.6 0.0 1.2e-11 44.6 0.0 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAM33448.1 - 1.6e-11 43.9 0.0 2.3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GAM33448.1 - 6.8e-10 38.5 0.4 9.7e-09 34.8 0.4 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 GAM33448.1 - 8.5e-08 32.3 0.0 1.8e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 GAM33448.1 - 6.2e-06 25.5 0.0 9.3e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 GAM33448.1 - 0.00014 21.4 0.0 0.00054 19.5 0.0 1.8 1 1 1 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 GAM33448.1 - 0.028 14.7 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F-box-like PF12937.7 GAM33450.1 - 0.00023 21.0 1.0 0.00023 21.0 1.0 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 GAM33450.1 - 0.0061 16.4 0.4 0.016 15.1 0.4 1.7 1 0 0 1 1 1 1 F-box domain Pentapeptide_4 PF13599.6 GAM33451.1 - 0.0011 19.1 0.1 0.23 11.7 0.1 3.0 1 1 1 2 2 2 1 Pentapeptide repeats (9 copies) TylF PF05711.11 GAM33451.1 - 0.056 12.7 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Pentapeptide_3 PF13576.6 GAM33451.1 - 0.12 12.6 0.0 24 5.2 0.0 2.5 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) MFS_1 PF07690.16 GAM33452.1 - 6.4e-34 117.4 36.2 4.5e-32 111.4 38.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily SH PF01445.17 GAM33452.1 - 0.076 13.0 0.6 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 Viral small hydrophobic protein Chordopox_L2 PF05803.12 GAM33452.1 - 0.1 12.4 0.1 0.33 10.8 0.1 1.9 1 0 0 1 1 1 0 Chordopoxvirus L2 protein DUF2627 PF11118.8 GAM33452.1 - 0.25 11.9 0.0 0.25 11.9 0.0 4.3 4 1 0 4 4 4 0 Protein of unknown function (DUF2627) Zn_clus PF00172.18 GAM33453.1 - 4.1e-05 23.6 13.1 7.1e-05 22.8 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAM33453.1 - 4.5e-05 22.4 0.0 0.00015 20.7 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain TSC22 PF01166.18 GAM33453.1 - 0.089 13.1 0.6 0.26 11.6 0.6 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family UPF0564 PF10595.9 GAM33453.1 - 0.11 11.5 0.2 0.15 11.1 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Lipase_2 PF01674.18 GAM33454.1 - 1.6e-07 31.1 0.0 1.1e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 GAM33454.1 - 0.00011 22.0 0.1 0.0017 18.1 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM33454.1 - 0.00039 21.1 0.4 0.00067 20.3 0.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM33454.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAM33454.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein GFA PF04828.14 GAM33455.1 - 1.1e-13 51.3 0.7 1.7e-13 50.7 0.7 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ABC_tran PF00005.27 GAM33456.1 - 1.3e-45 155.3 0.0 1.1e-27 97.2 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAM33456.1 - 2.6e-35 122.4 29.2 9.9e-24 84.4 13.5 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 GAM33456.1 - 2.7e-13 49.9 3.0 5.2e-07 29.3 1.1 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAM33456.1 - 2.6e-07 30.7 0.8 0.62 9.8 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAM33456.1 - 2.9e-07 30.8 0.2 0.014 15.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAM33456.1 - 1.1e-05 25.4 0.2 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 GAM33456.1 - 2.3e-05 24.0 3.0 0.021 14.5 0.6 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAM33456.1 - 0.00016 22.2 0.0 0.64 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 GAM33456.1 - 0.00021 21.3 0.1 0.36 10.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 GAM33456.1 - 0.00046 20.6 1.1 1.6 9.1 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 GAM33456.1 - 0.00061 19.4 0.9 0.031 13.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 GAM33456.1 - 0.0014 18.8 0.1 2.1 8.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 GAM33456.1 - 0.0037 16.9 1.8 0.23 11.0 0.1 3.0 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 GAM33456.1 - 0.013 15.6 1.3 0.043 13.9 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 GAM33456.1 - 0.014 15.5 3.0 0.72 9.9 0.1 3.1 3 0 0 3 3 3 0 Dynamin family T2SSE PF00437.20 GAM33456.1 - 0.017 14.2 1.1 1.5 7.9 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.6 GAM33456.1 - 0.021 14.5 0.0 3.7 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 GAM33456.1 - 0.026 14.4 0.3 7.3 6.5 0.2 2.6 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 GAM33456.1 - 0.065 12.6 0.4 5.4 6.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 GAM33456.1 - 0.082 12.2 0.5 11 5.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 GAM33456.1 - 0.082 12.4 0.1 8.3 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 GAM33456.1 - 0.094 12.1 0.0 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 GAM33456.1 - 0.11 11.8 0.4 8.1 5.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 GAM33456.1 - 0.13 12.0 0.4 19 4.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAM33456.1 - 0.15 12.6 0.0 30 5.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 GAM33456.1 - 0.18 10.5 2.4 0.31 9.8 0.0 2.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class MIP PF00230.20 GAM33457.1 - 4e-32 111.8 7.4 5.9e-32 111.2 7.4 1.3 1 1 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.16 GAM33458.1 - 4.7e-40 137.6 48.6 7.8e-40 136.9 46.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM33458.1 - 1.4e-12 46.8 13.3 2.4e-12 46.1 13.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM33458.1 - 3.1e-12 46.1 9.3 3.1e-12 46.1 9.3 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter VGCC_alpha2 PF08473.11 GAM33458.1 - 0.3 9.8 0.6 3.4 6.3 0.1 2.0 2 0 0 2 2 2 0 Neuronal voltage-dependent calcium channel alpha 2acd Glyco_hydro_71 PF03659.14 GAM33460.1 - 3.5e-91 305.8 3.1 4e-91 305.6 3.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Sugar_tr PF00083.24 GAM33461.1 - 3e-75 253.8 21.5 3.6e-75 253.6 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM33461.1 - 3.1e-18 65.8 38.0 1.2e-17 63.9 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAM33461.1 - 0.014 13.7 2.5 0.021 13.2 1.4 1.7 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 GAM33462.1 - 1.8e-09 37.5 13.3 4e-09 36.4 13.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM33462.1 - 1e-08 34.6 4.3 1.5e-08 34.0 4.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bac_rhamnosid6H PF17389.2 GAM33463.1 - 1.3e-20 73.9 2.6 2.4e-11 43.5 0.1 4.2 4 0 0 4 4 4 3 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_36 PF17167.4 GAM33463.1 - 0.00027 19.7 0.3 0.35 9.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_hydro_2_N PF02837.18 GAM33463.1 - 0.0014 18.5 0.0 0.0054 16.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain ESR1_C PF12743.7 GAM33463.1 - 0.18 11.6 1.0 9.5 6.1 0.1 4.0 5 0 0 5 5 5 0 Oestrogen-type nuclear receptor final C-terminal Bac_rhamnosid6H PF17389.2 GAM33464.1 - 5.4e-15 55.5 1.6 1.1e-12 47.9 0.8 2.5 1 1 2 3 3 3 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 GAM33464.1 - 7.1e-06 25.7 0.0 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 GAM33464.1 - 0.00027 19.9 0.1 0.00039 19.4 0.1 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_79C PF16862.5 GAM33465.1 - 6.4e-19 68.8 0.4 1.3e-18 67.8 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Jacalin PF01419.17 GAM33467.1 - 3.9e-05 23.6 0.0 0.0001 22.2 0.0 1.7 1 1 0 1 1 1 1 Jacalin-like lectin domain DIOX_N PF14226.6 GAM33468.1 - 4.7e-32 111.2 0.0 7.5e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM33468.1 - 1.9e-24 86.0 0.0 3.5e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 GAM33469.1 - 0.00074 18.6 0.2 0.00074 18.6 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain TssO PF17561.2 GAM33469.1 - 0.035 14.2 0.1 0.062 13.4 0.1 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO F-box PF00646.33 GAM33470.1 - 6.1e-05 22.8 0.4 0.00011 21.9 0.1 1.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GAM33470.1 - 0.026 14.4 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 F-box-like zf-dskA_traR PF01258.17 GAM33470.1 - 0.051 13.5 1.0 0.087 12.8 1.0 1.3 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger MFS_1 PF07690.16 GAM33472.1 - 3.4e-30 105.2 28.2 3.4e-30 105.2 28.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4752 PF15944.5 GAM33472.1 - 0.11 12.5 0.4 11 6.1 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4752) Fungal_trans_2 PF11951.8 GAM33473.1 - 3.3e-05 22.9 0.4 0.037 12.8 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain TctB PF07331.11 GAM33475.1 - 0.87 9.9 6.7 3 8.1 6.8 1.9 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Sugar_tr PF00083.24 GAM33476.1 - 2.4e-78 264.0 26.2 2.8e-78 263.8 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM33476.1 - 3.1e-18 65.8 37.6 2e-16 59.9 29.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2_2 PF12756.7 GAM33477.1 - 6.8e-07 29.6 0.5 0.00083 19.7 0.1 2.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAM33477.1 - 0.00045 20.8 7.8 0.019 15.7 1.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM33477.1 - 0.004 17.5 9.6 0.11 13.0 2.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 GAM33477.1 - 0.85 10.0 6.2 1.3 9.4 0.6 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding ADH_N PF08240.12 GAM33478.1 - 1.2e-05 25.1 0.0 3.2e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM33478.1 - 0.0029 17.6 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_76 PF03663.14 GAM33479.1 - 7.2e-42 144.2 18.2 9.7e-42 143.8 18.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 GAM33479.1 - 0.00018 20.7 1.9 0.022 13.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 PPP4R2 PF09184.11 GAM33479.1 - 0.0045 16.6 8.6 0.0066 16.1 8.6 1.1 1 0 0 1 1 1 1 PPP4R2 Glyco_hydro_127 PF07944.12 GAM33479.1 - 0.013 14.0 0.1 0.59 8.6 0.0 2.2 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Phage_holin_5_1 PF06946.11 GAM33479.1 - 0.15 12.5 0.7 9.4 6.7 0.0 2.7 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 SpoIIIAH PF12685.7 GAM33479.1 - 1.1 9.1 7.0 2 8.2 7.0 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.12 GAM33479.1 - 5 5.2 18.5 6 4.9 18.5 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 GAM33479.1 - 5.1 6.3 19.7 8.2 5.6 19.7 1.2 1 0 0 1 1 1 0 NOA36 protein PhetRS_B1 PF18262.1 GAM33480.1 - 3.8 7.8 5.4 3.3 8.0 2.2 2.3 2 1 1 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain NAD_binding_1 PF00175.21 GAM33482.1 - 6.2e-30 104.1 0.0 1e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAM33482.1 - 6.1e-17 61.8 0.0 1.1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAM33482.1 - 3.9e-06 27.1 0.0 0.0015 18.7 0.0 2.4 1 1 0 2 2 2 2 Ferric reductase NAD binding domain Acyl_transf_3 PF01757.22 GAM33483.1 - 1e-05 24.8 36.4 2.2e-05 23.7 36.4 1.5 1 0 0 1 1 1 1 Acyltransferase family Glyco_hydro_16 PF00722.21 GAM33483.1 - 0.00011 21.7 0.4 0.00027 20.5 0.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 GAM33484.1 - 1.9e-17 63.9 9.3 1.9e-17 63.9 9.3 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAM33484.1 - 4.8e-15 56.1 0.0 6.4e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAM33484.1 - 0.005 16.7 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAM33484.1 - 0.0085 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 MSV199 PF10553.9 GAM33484.1 - 0.031 14.5 1.1 0.61 10.3 0.1 2.3 2 0 0 2 2 2 0 MSV199 domain DUF418 PF04235.12 GAM33485.1 - 0.0038 17.2 0.8 0.0038 17.2 0.8 3.5 2 1 1 4 4 4 1 Protein of unknown function (DUF418) Alkyl_sulf_dimr PF14863.6 GAM33486.1 - 8e-55 185.1 0.1 1.2e-54 184.6 0.1 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.6 GAM33486.1 - 1.5e-12 47.9 0.0 3.4e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.27 GAM33486.1 - 6.6e-07 29.5 0.0 1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF1254 PF06863.12 GAM33487.1 - 4.5e-16 59.1 0.0 6.7e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1254) DUF2025 PF09634.10 GAM33487.1 - 0.024 14.7 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2025) MFS_1 PF07690.16 GAM33488.1 - 2.7e-29 102.2 32.7 2.7e-29 102.2 32.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Csa1 PF06023.12 GAM33489.1 - 0.058 12.8 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Questin_oxidase PF14027.6 GAM33490.1 - 2.8e-70 237.6 0.3 3.2e-70 237.3 0.3 1.0 1 0 0 1 1 1 1 Questin oxidase-like Helicase_C PF00271.31 GAM33492.1 - 2e-11 44.2 0.0 4.9e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM33492.1 - 1.2e-08 35.0 0.1 6.6e-08 32.5 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAM33492.1 - 5.4e-05 23.3 0.0 0.0007 19.6 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RVT_2 PF07727.14 GAM33493.1 - 9e-40 136.8 0.0 1.6e-39 136.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.6 GAM33493.1 - 7.6e-09 35.3 0.0 2.1e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 GAM33493.1 - 1.4e-08 35.0 0.1 1.8e-07 31.3 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 GAM33493.1 - 4.6e-05 23.1 9.1 0.14 11.9 0.0 5.7 6 0 0 6 6 6 2 Integrase core domain Retrotran_gag_2 PF14223.6 GAM33493.1 - 0.1 12.3 1.1 1.5 8.5 0.1 2.9 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Fungal_trans PF04082.18 GAM33495.1 - 3.6e-06 26.2 0.1 6.5e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_2 PF00891.18 GAM33496.1 - 3.7e-27 95.0 0.1 6e-27 94.3 0.1 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Peptidase_M24 PF00557.24 GAM33496.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase family M24 adh_short_C2 PF13561.6 GAM33497.1 - 1.2e-58 198.5 0.1 1.4e-58 198.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM33497.1 - 1.8e-48 164.6 0.0 2.2e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM33497.1 - 2.7e-12 47.0 0.0 4.1e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAM33497.1 - 0.0014 17.9 0.2 0.037 13.4 0.0 2.5 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 GAM33497.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 GAM33497.1 - 0.14 12.1 0.3 0.2 11.5 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-MYND PF01753.18 GAM33498.1 - 1.6e-08 34.5 8.8 3e-08 33.6 8.8 1.5 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 GAM33498.1 - 0.021 16.0 0.7 0.021 16.0 0.7 2.2 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins zf-C6H2 PF15801.5 GAM33498.1 - 2.1 8.7 8.6 6.6 7.1 8.6 1.9 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding MFS_1 PF07690.16 GAM33499.1 - 1.8e-30 106.1 33.7 1.8e-30 106.1 33.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM33499.1 - 0.00076 18.9 21.3 0.0016 17.8 6.0 2.4 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 GAM33499.1 - 0.00087 18.2 13.0 0.0018 17.2 12.9 1.4 1 1 0 1 1 1 1 MFS_1 like family MaAIMP_sms PF16951.5 GAM33499.1 - 0.088 12.6 1.3 8.3 6.2 0.0 3.6 3 0 0 3 3 3 0 Putative methionine and alanine importer, small subunit DUF21 PF01595.20 GAM33499.1 - 0.15 11.8 5.3 0.053 13.2 0.9 2.4 2 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain DUF2417 PF10329.9 GAM33499.1 - 0.38 10.1 3.6 0.83 9.0 3.6 1.5 1 0 0 1 1 1 0 Region of unknown function (DUF2417) M20_dimer PF07687.14 GAM33500.1 - 5.6e-07 29.5 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF4607 PF15380.6 GAM33500.1 - 0.041 13.4 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) Fungal_trans_2 PF11951.8 GAM33501.1 - 4.1e-13 48.9 0.9 2.3e-11 43.1 0.9 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM33501.1 - 1.9e-08 34.3 10.3 3e-08 33.6 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Endotoxin_M PF00555.19 GAM33502.1 - 0.043 13.9 0.0 0.066 13.2 0.0 1.2 1 0 0 1 1 1 0 delta endotoxin CBM9_2 PF16011.5 GAM33503.1 - 2.6e-05 24.0 0.1 3.3e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate-binding family 9 Ank_2 PF12796.7 GAM33504.1 - 5.1e-77 254.5 13.7 7.5e-15 55.3 1.0 10.9 3 2 7 11 11 11 10 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM33504.1 - 1.5e-59 190.9 4.4 7.5e-05 22.8 0.0 17.1 16 1 1 17 17 17 12 Ankyrin repeat Ank_4 PF13637.6 GAM33504.1 - 2.2e-56 187.5 7.3 3.1e-10 40.4 0.0 12.6 5 3 9 14 14 14 11 Ankyrin repeats (many copies) Ank PF00023.30 GAM33504.1 - 1.8e-45 151.5 15.1 1.3e-05 25.4 0.0 15.8 13 1 2 15 15 15 8 Ankyrin repeat Ank_5 PF13857.6 GAM33504.1 - 6e-42 141.2 18.5 2.4e-08 34.1 0.0 11.6 5 2 8 13 13 13 11 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 GAM33504.1 - 2e-10 40.3 0.1 1.8e-09 37.2 0.0 2.3 2 0 0 2 2 2 1 Phosphorylase superfamily AAA_16 PF13191.6 GAM33504.1 - 8.3e-06 26.3 1.9 3.4e-05 24.3 0.0 3.0 4 0 0 4 4 4 1 AAA ATPase domain NACHT PF05729.12 GAM33504.1 - 2.9e-05 24.1 0.5 0.00025 21.0 0.5 2.4 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GAM33504.1 - 0.0051 17.1 0.2 0.061 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAM33504.1 - 0.0059 16.3 0.0 0.033 13.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain HTH_15 PF12324.8 GAM33504.1 - 0.026 14.5 3.2 0.25 11.3 0.0 4.1 3 1 1 4 4 4 0 Helix-turn-helix domain of alkylmercury lyase Sugar_tr PF00083.24 GAM33505.1 - 1.3e-76 258.3 23.3 1.5e-76 258.1 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM33505.1 - 3.9e-27 95.1 33.4 6.3e-26 91.1 19.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM33505.1 - 5e-06 25.2 1.6 9.4e-06 24.3 1.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_3_C PF01915.22 GAM33506.1 - 3e-56 190.6 0.0 6.8e-56 189.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAM33506.1 - 5.7e-39 134.3 0.0 1e-38 133.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM33506.1 - 2.6e-24 85.1 0.0 4.9e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 GAM33506.1 - 7.4e-15 55.0 0.1 1.7e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 PA14 domain Caps_synth PF05704.12 GAM33507.1 - 1.5e-12 47.5 0.0 2.4e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 GAM33507.1 - 4.4e-05 24.0 0.0 7.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif OmpH PF03938.14 GAM33508.1 - 2 8.7 13.6 3.9 7.8 4.9 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4355 PF14265.6 GAM33508.1 - 6.5 7.0 20.8 3.1 8.1 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) PNISR PF15996.5 GAM33508.1 - 8.1 6.7 18.8 16 5.7 18.8 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR MFS_1 PF07690.16 GAM33509.1 - 2.1e-33 115.7 25.9 2.1e-33 115.7 25.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 GAM33509.1 - 2.8e-10 40.1 10.6 4.8e-10 39.4 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRI12 PF06609.13 GAM33509.1 - 3.6e-08 32.3 5.8 6.3e-08 31.5 5.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3961 PF13106.6 GAM33509.1 - 0.16 11.6 0.9 20 4.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) ABC_tran PF00005.27 GAM33510.1 - 1.6e-51 174.4 0.1 4.4e-30 105.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAM33510.1 - 4.4e-29 102.0 9.9 6.9e-29 101.3 9.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 GAM33510.1 - 5e-12 45.7 3.9 0.0011 18.4 0.3 4.2 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain Lactamase_B PF00753.27 GAM33510.1 - 1.7e-09 38.0 0.2 1.4e-07 31.8 0.1 2.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily AAA_21 PF13304.6 GAM33510.1 - 2.8e-07 30.7 0.2 0.071 12.9 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM33510.1 - 1.4e-06 27.9 0.2 0.027 14.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GAM33510.1 - 4.1e-06 27.1 0.3 0.025 14.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 GAM33510.1 - 5.4e-05 23.6 0.0 0.23 11.9 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 GAM33510.1 - 5.5e-05 23.8 0.3 0.51 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 GAM33510.1 - 5.7e-05 22.1 2.4 0.36 9.6 0.0 3.4 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 GAM33510.1 - 0.00018 21.9 0.1 0.024 15.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAM33510.1 - 0.00027 20.9 0.4 1.2 9.1 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM33510.1 - 0.00043 20.4 0.1 0.46 10.6 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 GAM33510.1 - 0.00046 19.3 0.1 0.14 11.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 GAM33510.1 - 0.00088 18.8 0.1 0.16 11.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region cobW PF02492.19 GAM33510.1 - 0.001 18.7 1.1 0.14 11.7 0.1 2.7 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 GAM33510.1 - 0.0013 18.6 0.1 0.064 13.2 0.1 2.5 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 GAM33510.1 - 0.0047 16.1 0.6 0.61 9.2 0.0 2.8 3 1 0 3 3 3 1 NB-ARC domain AAA_25 PF13481.6 GAM33510.1 - 0.0051 16.4 4.7 0.076 12.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 GAM33510.1 - 0.03 14.4 1.2 3.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_15 PF13175.6 GAM33510.1 - 0.034 13.9 0.0 6 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 GAM33510.1 - 0.036 13.2 0.0 5 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 GAM33510.1 - 0.047 13.0 0.2 9.8 5.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 GAM33510.1 - 0.054 12.8 0.1 8.6 5.6 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 GAM33510.1 - 0.061 13.0 0.2 4.7 6.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAM33510.1 - 0.084 13.0 0.1 1.8 8.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GAM33510.1 - 0.087 13.2 0.9 22 5.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 GAM33510.1 - 0.098 12.7 0.7 3.3 7.7 0.1 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAM33510.1 - 0.11 13.0 0.0 18 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 GAM33510.1 - 0.15 12.1 2.4 1.7 8.7 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 GAM33510.1 - 0.16 12.4 0.0 29 5.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 GAM33510.1 - 0.21 11.6 0.2 8.8 6.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sulf_transp PF04143.14 GAM33510.1 - 0.55 9.7 8.9 0.49 9.9 0.7 2.3 2 0 0 2 2 2 0 Sulphur transport MFS_1 PF07690.16 GAM33511.1 - 2.9e-31 108.7 39.2 2.9e-31 108.7 39.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2838 PF10998.8 GAM33511.1 - 0.011 15.9 1.0 0.011 15.9 1.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2838) AMP-binding PF00501.28 GAM33512.1 - 1.2e-92 310.8 0.0 1.4e-92 310.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM33512.1 - 6.8e-12 46.2 0.0 1.7e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FMO-like PF00743.19 GAM33513.1 - 5.9e-23 81.1 0.0 4.3e-21 74.9 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 GAM33513.1 - 4.8e-10 39.5 0.0 1.2e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM33513.1 - 2.9e-09 36.6 0.0 7.9e-06 25.3 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM33513.1 - 1.9e-07 30.6 0.0 0.0029 16.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM33513.1 - 3.9e-07 29.5 0.0 1.2e-05 24.6 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAM33513.1 - 0.0017 18.4 0.0 0.24 11.4 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 GAM33513.1 - 0.0045 16.3 0.0 0.07 12.4 0.0 2.6 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase DAO PF01266.24 GAM33513.1 - 0.006 16.2 0.0 0.052 13.1 0.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAM33513.1 - 0.065 12.5 0.0 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Fungal_trans PF04082.18 GAM33514.1 - 2.3e-10 40.0 0.1 5e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 GAM33515.1 - 3.7e-45 154.4 0.0 5.1e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAM33515.1 - 5.1e-10 38.8 0.1 1.7e-09 37.1 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family adh_short_C2 PF13561.6 GAM33516.1 - 1.4e-55 188.4 1.8 2.5e-55 187.6 1.8 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM33516.1 - 2.2e-44 151.3 2.5 4.1e-44 150.4 2.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase FMO-like PF00743.19 GAM33516.1 - 6.9e-15 54.5 0.7 2e-14 53.0 0.2 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 GAM33516.1 - 6.6e-07 29.5 0.0 3.5e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAM33516.1 - 0.00011 21.5 0.0 0.0096 15.1 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAM33516.1 - 0.00025 20.4 0.0 0.011 15.0 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 GAM33516.1 - 0.15 11.9 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 GAM33517.1 - 8.1e-29 100.5 0.0 3.6e-27 95.1 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33517.1 - 4.8e-21 75.4 0.0 2.5e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 GAM33517.1 - 3.7e-20 71.8 0.1 7e-20 70.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM33517.1 - 1.1e-17 64.2 0.7 2.1e-17 63.3 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM33517.1 - 6.8e-09 36.9 0.0 1.7e-08 35.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.10 GAM33517.1 - 4.6e-06 26.7 0.0 0.026 14.4 0.0 3.3 3 0 0 3 3 3 2 KR domain AlaDh_PNT_C PF01262.21 GAM33517.1 - 0.0068 15.7 0.1 0.023 14.0 0.1 1.8 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N PF00107.26 GAM33518.1 - 1.7e-18 66.9 0.0 2.1e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 GAM33518.1 - 0.00096 19.9 0.0 0.0016 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAM33518.1 - 0.079 12.7 0.0 0.092 12.5 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein Aldedh PF00171.22 GAM33519.1 - 1.9e-131 438.8 0.1 2.4e-131 438.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAM33519.1 - 0.015 14.8 0.0 0.045 13.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) p450 PF00067.22 GAM33520.1 - 8.2e-72 242.4 0.0 1.1e-71 242.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2373 PF10180.9 GAM33520.1 - 0.094 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Fungal_trans PF04082.18 GAM33521.1 - 4.9e-08 32.3 0.1 8.6e-08 31.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM33521.1 - 3.3e-07 30.3 7.1 6.2e-07 29.4 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Questin_oxidase PF14027.6 GAM33522.1 - 3.5e-77 260.3 0.2 4.3e-77 260.0 0.2 1.1 1 0 0 1 1 1 1 Questin oxidase-like Zn_clus PF00172.18 GAM33523.1 - 2.5e-09 37.1 10.8 5e-09 36.1 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5440 PF17509.2 GAM33523.1 - 0.089 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5440) DUF2263 PF10021.9 GAM33524.1 - 9.7e-20 71.4 0.0 2.8e-19 69.9 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 GAM33524.1 - 0.039 14.0 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Macro domain AMP-binding PF00501.28 GAM33525.1 - 2e-56 191.4 0.0 5.1e-56 190.1 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 GAM33525.1 - 1.7e-13 50.1 0.0 4.1e-13 48.8 0.0 1.6 1 1 0 1 1 1 1 Condensation domain Ank_2 PF12796.7 GAM33525.1 - 2.9e-12 47.0 2.0 2.8e-07 31.0 0.3 4.0 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) AMP-binding_C PF13193.6 GAM33525.1 - 1e-08 36.0 0.0 2.9e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ank_4 PF13637.6 GAM33525.1 - 2e-07 31.4 0.5 9.8e-06 26.0 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM33525.1 - 1.8e-06 27.8 0.1 3.4 8.5 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 GAM33525.1 - 2.1e-06 27.9 1.1 0.31 11.4 0.0 4.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) PP-binding PF00550.25 GAM33525.1 - 1.1e-05 25.6 1.1 3e-05 24.3 1.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ank PF00023.30 GAM33525.1 - 0.081 13.4 0.2 4.6 7.9 0.0 3.5 2 1 0 2 2 2 0 Ankyrin repeat NAD_synthase PF02540.17 GAM33526.1 - 0.1 11.7 0.2 0.14 11.2 0.2 1.1 1 0 0 1 1 1 0 NAD synthase ARL6IP6 PF15062.6 GAM33526.1 - 0.15 12.2 0.6 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix p450 PF00067.22 GAM33527.1 - 6.7e-50 170.2 0.0 9e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 GAM33528.1 - 1.8e-41 141.7 0.1 2.6e-41 141.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33528.1 - 8.7e-30 104.0 0.1 1.3e-29 103.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 GAM33528.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 GAM33528.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TauD PF02668.16 GAM33529.1 - 2.6e-54 184.8 0.3 3.1e-54 184.6 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ketoacyl-synt PF00109.26 GAM33530.1 - 1.2e-70 238.0 0.0 2.3e-70 237.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAM33530.1 - 1.1e-48 165.6 0.0 5.1e-48 163.4 0.0 2.1 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 GAM33530.1 - 5.5e-46 157.1 0.0 1.1e-45 156.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAM33530.1 - 1.1e-37 130.3 0.1 2e-37 129.4 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM33530.1 - 2.3e-29 101.8 0.0 6.8e-29 100.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 GAM33530.1 - 8.8e-19 68.1 0.0 2.6e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAM33530.1 - 4.7e-15 56.0 0.0 1.3e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 GAM33530.1 - 5.9e-15 55.5 0.0 1.8e-14 54.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM33530.1 - 1.8e-12 47.8 0.0 9.6e-12 45.5 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM33530.1 - 1.7e-11 44.6 0.0 4.4e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM33530.1 - 1.9e-11 43.9 0.0 4.1e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 GAM33530.1 - 4.5e-09 36.0 0.1 1.2e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 GAM33530.1 - 2e-07 31.3 0.1 5.4e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 GAM33530.1 - 3.9e-06 26.6 0.0 1e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 GAM33530.1 - 7.1e-06 25.5 0.0 1.8e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 GAM33530.1 - 0.00022 20.7 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 GAM33530.1 - 0.00045 20.0 0.0 0.00098 18.9 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase DREV PF05219.12 GAM33530.1 - 0.048 12.7 0.0 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 DREV methyltransferase NodS PF05401.11 GAM33530.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) FSH1 PF03959.13 GAM33532.1 - 7.6e-22 78.0 0.0 1.4e-20 73.9 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) p450 PF00067.22 GAM33533.1 - 3.3e-70 237.1 0.0 4.4e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 GAM33534.1 - 1.3e-08 34.9 0.0 2.3e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM33534.1 - 1.4e-06 28.2 0.8 3.1e-06 27.0 0.6 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM33534.1 - 0.00066 20.7 0.0 0.0013 19.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cpn10 PF00166.21 GAM33534.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit p450 PF00067.22 GAM33535.1 - 7.4e-52 176.6 0.0 1e-51 176.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Toxin_YhaV PF11663.8 GAM33535.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Toxin with endonuclease activity, of toxin-antitoxin system ABC_membrane PF00664.23 GAM33537.1 - 4.9e-52 177.3 25.7 1.5e-29 103.5 10.4 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 GAM33537.1 - 8.4e-51 172.1 0.1 1.8e-26 93.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 GAM33537.1 - 2.7e-07 30.6 2.2 0.024 14.7 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 GAM33537.1 - 5.6e-07 29.2 1.6 0.0051 16.5 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 GAM33537.1 - 5.6e-07 29.9 5.2 0.00057 20.0 0.4 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_16 PF13191.6 GAM33537.1 - 6.8e-07 29.8 0.4 0.011 16.1 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 GAM33537.1 - 9.6e-07 28.9 0.9 0.33 10.7 0.4 3.7 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM33537.1 - 2.2e-06 27.3 2.1 1.3 8.4 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAM33537.1 - 0.00016 22.2 0.3 0.32 11.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAM33537.1 - 0.00049 20.0 3.2 0.56 10.1 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase FtsK_SpoIIIE PF01580.18 GAM33537.1 - 0.00055 19.4 2.3 0.47 9.8 0.0 2.6 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_7 PF12775.7 GAM33537.1 - 0.00096 18.7 0.9 0.35 10.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 GAM33537.1 - 0.0024 17.5 0.5 0.98 9.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 GAM33537.1 - 0.0046 16.2 0.8 1.4 8.0 0.0 2.6 2 1 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.23 GAM33537.1 - 0.0088 16.1 2.7 1.3 9.0 0.1 2.7 2 0 0 2 2 2 1 Dynamin family T2SSE PF00437.20 GAM33537.1 - 0.011 14.8 0.1 0.094 11.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 GAM33537.1 - 0.012 15.6 0.4 2.1 8.2 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 GAM33537.1 - 0.017 15.4 5.4 0.94 9.7 0.3 2.9 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 GAM33537.1 - 0.023 13.9 0.5 0.24 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 GAM33537.1 - 0.033 13.9 0.2 6.5 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAM33537.1 - 0.035 13.8 0.1 9.2 6.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_ATPase PF09818.9 GAM33537.1 - 0.039 12.8 1.1 6.6 5.4 0.1 3.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_10 PF12846.7 GAM33537.1 - 0.04 12.8 1.4 0.26 10.2 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.12 GAM33537.1 - 0.053 12.8 1.0 4.2 6.6 0.1 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 GAM33537.1 - 0.061 13.0 0.8 7.6 6.2 0.2 2.5 2 0 0 2 2 2 0 AAA domain DHHW PF14286.6 GAM33537.1 - 0.069 12.5 0.1 0.15 11.3 0.1 1.5 2 0 0 2 2 1 0 DHHW protein Ploopntkinase3 PF18751.1 GAM33537.1 - 0.071 13.0 0.3 4.5 7.2 0.1 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 GAM33537.1 - 0.073 13.2 0.3 13 5.9 0.2 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 GAM33537.1 - 0.096 12.9 0.5 17 5.7 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 GAM33537.1 - 0.12 12.1 3.8 6.3 6.5 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 GAM33537.1 - 0.12 12.7 0.8 20 5.6 0.0 3.2 3 0 0 3 3 3 0 RNA helicase Ank PF00023.30 GAM33538.1 - 8.9e-28 95.5 3.8 2.2e-07 31.0 0.1 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 GAM33538.1 - 3e-26 91.8 0.1 7.8e-12 45.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM33538.1 - 3.2e-23 81.5 0.5 4.8e-11 42.7 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM33538.1 - 8.8e-22 74.9 0.5 0.00049 20.3 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 GAM33538.1 - 3e-18 65.9 0.1 2.9e-07 30.9 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Metallophos_C PF14008.6 GAM33539.1 - 1.1e-15 58.3 0.0 2.7e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 GAM33539.1 - 3e-15 57.3 0.0 4.9e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 GAM33539.1 - 5.6e-12 46.1 4.3 1.2e-11 45.0 4.3 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Cupin_2 PF07883.11 GAM33539.1 - 0.0062 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain PhoD_N PF16655.5 GAM33539.1 - 0.0098 16.4 0.1 0.024 15.1 0.1 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain ADD_DNMT3 PF17980.1 GAM33539.1 - 0.45 10.6 1.6 3.3 7.8 0.2 2.2 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 p450 PF00067.22 GAM33540.1 - 3.4e-23 82.1 0.1 4.8e-13 48.7 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Phosphoesterase PF04185.14 GAM33541.1 - 7.4e-69 232.6 3.0 3.7e-68 230.3 0.2 2.2 2 0 0 2 2 2 2 Phosphoesterase family RicinB_lectin_2 PF14200.6 GAM33541.1 - 0.0077 16.9 2.4 0.13 13.0 0.7 2.7 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like GATase PF00117.28 GAM33542.1 - 2.4e-36 125.3 0.0 1.3e-35 122.9 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 GAM33542.1 - 1.2e-34 118.2 0.0 2.7e-34 117.1 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 GAM33542.1 - 4.6e-07 29.2 0.0 0.00017 20.8 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 GAM33542.1 - 9.6e-06 25.5 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 PAPS_reduct PF01507.19 GAM33542.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Disulph_isomer PF06491.11 GAM33542.1 - 0.2 11.8 0.0 0.43 10.7 0.0 1.5 1 0 0 1 1 1 0 Disulphide isomerase tRNA_Me_trans PF03054.16 GAM33542.1 - 0.22 10.3 0.0 0.4 9.4 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase FMN_dh PF01070.18 GAM33543.1 - 1.8e-94 316.6 0.0 3e-94 315.9 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase MFS_1 PF07690.16 GAM33543.1 - 5e-36 124.3 28.0 7e-36 123.9 28.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glu_synthase PF01645.17 GAM33543.1 - 9.1e-06 25.0 0.0 1.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase MFS_4 PF06779.14 GAM33543.1 - 9.6e-06 25.1 2.9 9.6e-06 25.1 2.9 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB IMPDH PF00478.25 GAM33543.1 - 0.00013 21.1 0.0 0.00051 19.1 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 GAM33543.1 - 0.015 14.7 0.3 0.028 13.8 0.0 1.5 2 0 0 2 2 2 0 Nitronate monooxygenase ThiG PF05690.14 GAM33543.1 - 0.095 12.0 0.1 3 7.1 0.0 2.5 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG TauD PF02668.16 GAM33544.1 - 3.2e-05 23.9 0.0 3.2e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4651 PF15513.6 GAM33544.1 - 0.14 12.0 0.0 11 5.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) TauD PF02668.16 GAM33545.1 - 1.5e-51 175.7 0.4 1.8e-51 175.5 0.4 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans PF04082.18 GAM33546.1 - 0.00018 20.6 0.5 0.00067 18.8 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain FAR1 PF03101.15 GAM33547.1 - 4.6e-08 33.6 0.2 9e-08 32.7 0.2 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 GAM33547.1 - 0.0094 16.3 2.9 0.085 13.3 0.6 2.6 2 1 0 2 2 2 1 Transcription factor AFT COesterase PF00135.28 GAM33548.1 - 6.8e-58 196.8 0.8 1.4e-45 156.2 0.0 3.0 1 1 2 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM33548.1 - 1.5e-05 25.0 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM33548.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Methyltransf_23 PF13489.6 GAM33550.1 - 2.4e-17 63.2 0.0 3.3e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM33550.1 - 5.2e-13 49.5 0.0 1.5e-12 48.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM33550.1 - 6.9e-10 39.5 0.0 5e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM33550.1 - 1.5e-08 34.5 0.0 2e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM33550.1 - 8.1e-08 32.9 0.0 4.3e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM33550.1 - 0.00023 20.6 0.0 0.0032 16.9 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 GAM33550.1 - 0.00051 19.8 0.0 0.00099 18.9 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAM33550.1 - 0.00075 19.1 0.0 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 GAM33550.1 - 0.0025 17.3 0.5 0.0081 15.6 0.0 2.0 3 0 0 3 3 3 1 Putative methyltransferase PrmA PF06325.13 GAM33550.1 - 0.0046 16.4 0.0 0.0086 15.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 GAM33550.1 - 0.01 16.0 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 GAM33550.1 - 0.02 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Oxidored_FMN PF00724.20 GAM33552.1 - 3e-61 207.6 0.0 3.2e-59 200.9 0.0 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1877 PF08974.10 GAM33552.1 - 0.088 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) DUF3638 PF12340.8 GAM33553.1 - 3.2e-88 294.9 0.7 5.5e-88 294.1 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 GAM33553.1 - 2.5e-16 58.8 0.0 5.2e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) SapB_1 PF05184.15 GAM33554.1 - 3e-08 33.5 3.2 9.8e-08 31.9 0.6 2.7 3 0 0 3 3 3 1 Saposin-like type B, region 1 SapB_2 PF03489.17 GAM33554.1 - 0.011 15.8 1.5 0.026 14.7 0.0 2.2 3 0 0 3 3 3 0 Saposin-like type B, region 2 Methyltransf_18 PF12847.7 GAM33554.1 - 0.077 12.9 0.1 0.084 12.8 0.1 1.0 1 0 0 1 1 1 0 Methyltransferase domain Mtr2 PF10429.9 GAM33556.1 - 0.097 12.6 0.0 0.27 11.2 0.0 1.7 1 1 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Methyltransf_23 PF13489.6 GAM33557.1 - 4.9e-22 78.5 0.0 7.2e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM33557.1 - 3.6e-10 40.4 0.0 8.8e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM33557.1 - 9.7e-08 31.9 0.0 3.5e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM33557.1 - 1.1e-06 29.1 0.0 5.6e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM33557.1 - 0.00018 22.2 0.0 0.00074 20.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 GAM33557.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 GAM33557.1 - 0.025 14.1 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 GAM33557.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 GAM33558.1 - 2.6e-23 82.5 0.0 3.9e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 GAM33558.1 - 0.00017 21.4 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM33558.1 - 0.026 15.2 0.0 0.056 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MutL PF13941.6 GAM33558.1 - 0.15 10.6 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 MutL protein Sugar_tr PF00083.24 GAM33559.1 - 4.1e-98 329.2 25.4 5.1e-98 328.9 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM33559.1 - 7.5e-35 120.5 47.9 1.1e-31 110.0 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM33559.1 - 0.0039 15.8 5.6 0.0039 15.8 5.6 3.2 2 1 0 3 3 3 2 MFS/sugar transport protein Phage_min_cap2 PF06152.11 GAM33559.1 - 0.089 11.7 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 FAA_hydrolase PF01557.18 GAM33560.1 - 9.2e-34 117.0 0.0 2e-33 115.9 0.0 1.5 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family GH43_C2 PF17851.1 GAM33560.1 - 1.2e-31 110.0 0.0 1.8e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_43 PF04616.14 GAM33560.1 - 2.8e-31 108.9 1.0 5.8e-19 68.5 0.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 FAA_hydrolase_N PF09298.11 GAM33560.1 - 3.9e-23 81.7 0.0 7.7e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Lactamase_B PF00753.27 GAM33561.1 - 2e-06 28.0 0.1 3.5e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM33561.1 - 0.002 17.7 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain adh_short_C2 PF13561.6 GAM33563.1 - 2.7e-26 92.6 0.0 3.5e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM33563.1 - 2.5e-23 82.6 0.0 3.3e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM33563.1 - 0.021 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 KR domain 3HCDH_N PF02737.18 GAM33563.1 - 0.062 13.2 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAM33563.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GAM33563.1 - 0.15 12.6 0.2 0.33 11.6 0.1 1.7 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ank_2 PF12796.7 GAM33564.1 - 8.2e-72 237.8 0.0 4.5e-13 49.6 0.0 7.1 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM33564.1 - 9.8e-58 185.3 0.1 8.1e-05 22.7 0.0 14.6 14 1 1 15 15 15 12 Ankyrin repeat Ank_4 PF13637.6 GAM33564.1 - 3.4e-55 183.7 0.1 3.2e-08 34.0 0.1 9.5 5 2 4 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 GAM33564.1 - 1.5e-49 164.3 0.5 3.7e-06 27.1 0.1 14.2 14 1 0 14 14 14 10 Ankyrin repeat Ank_5 PF13857.6 GAM33564.1 - 1.2e-45 152.9 7.7 2.1e-07 31.1 0.1 11.0 3 3 9 12 12 12 11 Ankyrin repeats (many copies) CorA PF01544.18 GAM33564.1 - 4.5e-06 26.2 0.5 7.7e-06 25.4 0.5 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein VWA_3_C PF18571.1 GAM33564.1 - 0.072 13.0 1.4 88 3.1 0.0 4.9 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain DUF3489 PF11994.8 GAM33564.1 - 0.087 12.9 0.0 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) 3HCDH_RFF PF18321.1 GAM33564.1 - 0.17 12.4 0.3 31 5.1 0.0 4.1 6 0 0 6 6 6 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain DUF3632 PF12311.8 GAM33565.1 - 8.1e-26 91.5 0.0 1.2e-25 91.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) AA_permease PF00324.21 GAM33566.1 - 1.9e-60 204.9 28.7 2.6e-50 171.4 12.3 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 GAM33566.1 - 4.3e-11 42.3 10.2 4.3e-11 42.3 10.2 2.0 1 1 1 2 2 2 2 Amino acid permease SID-1_RNA_chan PF13965.6 GAM33566.1 - 0.00086 17.8 2.3 0.0014 17.1 2.3 1.3 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 RCC1 PF00415.18 GAM33567.1 - 8.8e-37 125.5 5.4 2.5e-11 44.0 0.1 5.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM33567.1 - 2e-31 107.1 14.8 1.1e-10 41.0 0.4 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat FTP PF07504.13 GAM33567.1 - 0.092 12.6 0.3 1.2 9.1 0.1 3.0 4 0 0 4 4 4 0 Fungalysin/Thermolysin Propeptide Motif Fungal_trans_2 PF11951.8 GAM33568.1 - 3.5e-45 154.5 0.5 4.3e-45 154.2 0.5 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4404 PF14357.6 GAM33568.1 - 0.14 12.8 1.7 0.84 10.3 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Abhydrolase_6 PF12697.7 GAM33569.1 - 2.4e-05 25.1 0.1 0.00013 22.7 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family ACOX PF01756.19 GAM33571.1 - 6.7e-32 110.5 0.4 2e-31 108.9 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 GAM33571.1 - 5.5e-23 81.9 0.7 5.5e-23 81.9 0.7 2.4 3 0 0 3 3 3 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 GAM33571.1 - 1.4e-07 31.6 0.0 3.5e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DctP PF03480.13 GAM33571.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 Acyl-CoA_dh_1 PF00441.24 GAM33571.1 - 0.17 12.1 1.1 1.2 9.4 1.1 2.5 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Nucleoside_tran PF01733.18 GAM33572.1 - 0.0037 16.7 0.0 0.0046 16.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoside transporter AMP-binding PF00501.28 GAM33573.1 - 3.4e-57 193.9 0.0 4.2e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM33573.1 - 2.1e-08 35.0 0.0 6.3e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 GAM33574.1 - 5.8e-21 74.9 0.0 8.7e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Fungal_trans PF04082.18 GAM33574.1 - 4.8e-14 52.0 0.1 8.4e-14 51.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH_2 PF16113.5 GAM33574.1 - 7.4e-08 32.3 0.0 1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Trypsin_2 PF13365.6 GAM33574.1 - 2.1e-06 28.7 0.0 4.6e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_C3 PF00548.20 GAM33574.1 - 0.041 13.8 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Trypsin PF00089.26 GAM33574.1 - 0.087 12.6 0.2 0.34 10.7 0.2 1.8 2 0 0 2 2 2 0 Trypsin Acetyltransf_1 PF00583.25 GAM33576.1 - 2.1e-06 28.0 0.0 2.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM33576.1 - 1.3e-05 25.5 0.0 1.9e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM33576.1 - 8.9e-05 22.4 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM33576.1 - 0.015 15.3 0.0 0.052 13.5 0.0 1.8 1 1 1 2 2 2 0 FR47-like protein OPT PF03169.15 GAM33577.1 - 6.1e-128 428.1 40.4 7e-128 427.9 40.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Tetraspanin PF00335.20 GAM33577.1 - 0.43 10.2 4.3 0.12 12.1 0.9 1.9 2 0 0 2 2 2 0 Tetraspanin family Arylsulfotrans PF05935.11 GAM33578.1 - 1.6e-18 66.8 0.0 3.5e-07 29.5 0.0 3.6 1 1 2 3 3 3 3 Arylsulfotransferase (ASST) Arylsulfotran_2 PF14269.6 GAM33578.1 - 4.3e-17 62.4 0.0 6.9e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.6 GAM33578.1 - 2.3e-06 27.3 0.0 6.3e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 PQQ-like domain MFS_1 PF07690.16 GAM33579.1 - 7.2e-34 117.3 29.2 7.2e-34 117.3 29.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.28 GAM33580.1 - 5.1e-101 338.3 0.0 6.2e-101 338.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM33580.1 - 8.6e-13 49.1 0.0 2.4e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain K_oxygenase PF13434.6 GAM33581.1 - 1e-116 389.9 0.1 1.2e-116 389.6 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAM33581.1 - 1.5e-13 50.7 0.0 2.2e-11 43.6 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM33581.1 - 1.1e-11 44.5 0.0 5.3e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM33581.1 - 9e-08 32.3 0.0 0.00012 22.1 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAM33581.1 - 0.0042 17.6 0.0 0.15 12.6 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM33581.1 - 0.024 14.2 0.0 29 4.1 0.0 3.3 3 1 0 3 3 3 0 FAD dependent oxidoreductase DUF3510 PF12022.8 GAM33581.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) DUF3632 PF12311.8 GAM33582.1 - 1.8e-17 64.3 0.0 2.6e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) p450 PF00067.22 GAM33583.1 - 5.5e-62 210.0 0.0 6.3e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FUN14 PF04930.15 GAM33583.1 - 0.2 12.1 0.1 0.58 10.6 0.1 1.7 1 0 0 1 1 1 0 FUN14 family Pyr_redox_2 PF07992.14 GAM33584.1 - 1.1e-26 93.7 0.0 9.8e-23 80.8 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EthD PF07110.11 GAM33584.1 - 5.2e-12 46.7 0.2 1.2e-11 45.6 0.2 1.6 1 0 0 1 1 1 1 EthD domain Pyr_redox PF00070.27 GAM33584.1 - 2.3e-11 44.1 1.8 4.8e-10 39.9 0.4 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM33584.1 - 6.6e-06 25.4 0.6 0.0054 15.8 0.1 2.4 1 1 1 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAM33584.1 - 3.3e-05 23.3 0.1 7.6e-05 22.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM33584.1 - 0.0023 17.1 0.0 0.0049 16.1 0.0 1.7 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 GAM33584.1 - 0.0028 16.6 0.5 2.8 6.7 0.3 3.1 3 0 0 3 3 3 1 Tryptophan halogenase DAO PF01266.24 GAM33584.1 - 0.014 15.0 1.9 0.1 12.2 0.1 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM33584.1 - 0.076 13.0 0.7 26 4.8 0.0 3.7 3 1 1 4 4 4 0 FAD-NAD(P)-binding ApbA PF02558.16 GAM33584.1 - 0.1 12.2 0.1 0.6 9.8 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 GAM33585.1 - 7.7e-07 29.2 0.5 4.2e-05 23.5 0.2 2.2 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 GAM33585.1 - 0.00069 19.1 0.1 0.0058 16.1 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAM33585.1 - 0.0058 16.6 0.1 0.0096 15.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 GAM33585.1 - 0.029 14.8 0.2 0.048 14.1 0.2 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 GAM33585.1 - 0.06 12.9 0.3 0.59 9.6 0.1 2.1 1 1 1 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.15 GAM33585.1 - 0.062 12.4 0.1 0.088 11.9 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GAM33585.1 - 0.076 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Sacchrp_dh_NADP PF03435.18 GAM33585.1 - 0.17 12.2 0.1 0.29 11.4 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Fungal_trans_2 PF11951.8 GAM33586.1 - 7.1e-37 127.1 2.3 1e-36 126.6 2.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF5021 PF16424.5 GAM33586.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5021) HAD_2 PF13419.6 GAM33587.1 - 3.3e-11 43.6 0.0 6.8e-11 42.6 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM33587.1 - 2.3e-08 34.6 0.0 5.8e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM33587.1 - 0.0022 18.0 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Radical_SAM PF04055.21 GAM33587.1 - 0.025 15.0 0.1 0.22 11.9 0.0 2.2 2 1 0 2 2 2 0 Radical SAM superfamily TPT PF03151.16 GAM33588.1 - 8.1e-28 97.6 27.3 1.2e-27 97.1 27.3 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GAM33588.1 - 0.0018 17.5 25.3 0.0028 16.9 25.3 1.3 1 0 0 1 1 1 1 UAA transporter family Dioxygenase_C PF00775.21 GAM33589.1 - 7.1e-39 133.1 0.0 9.6e-39 132.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 GAM33589.1 - 3.1e-28 97.4 0.0 5.3e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus DUF824 PF05688.11 GAM33589.1 - 0.037 13.9 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) STAT_alpha PF01017.20 GAM33590.1 - 0.078 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain FAD_binding_3 PF01494.19 GAM33593.1 - 2.8e-49 168.3 0.0 4.1e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM33593.1 - 1e-07 31.9 0.2 1e-05 25.3 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM33593.1 - 9.9e-07 28.9 0.2 3.5e-05 23.9 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAM33593.1 - 9.6e-05 21.2 0.2 0.00064 18.5 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 GAM33593.1 - 0.0004 19.8 0.0 0.00065 19.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM33593.1 - 0.00048 19.3 0.1 0.0021 17.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM33593.1 - 0.0015 17.8 0.1 0.0028 16.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM33593.1 - 0.0017 17.7 0.2 0.0062 15.8 0.1 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 GAM33593.1 - 0.002 18.0 0.1 0.0052 16.7 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 GAM33593.1 - 0.0056 16.3 0.3 0.015 14.9 0.1 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 GAM33593.1 - 0.0064 15.8 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 GAM33593.1 - 0.012 14.7 0.2 0.044 12.8 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 GAM33593.1 - 0.016 15.7 0.0 0.71 10.5 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 GAM33593.1 - 0.1 12.3 0.3 0.23 11.1 0.3 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 GAM33593.1 - 0.16 12.5 0.0 0.46 11.0 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain Fungal_trans PF04082.18 GAM33594.1 - 5.9e-18 64.9 0.7 1.1e-17 64.0 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRI12 PF06609.13 GAM33595.1 - 4.3e-32 111.3 23.5 5.7e-32 110.9 23.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 GAM33595.1 - 7.7e-21 74.4 49.6 9.5e-21 74.1 46.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM33595.1 - 0.0011 17.9 26.5 0.0038 16.2 9.5 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter Syndecan PF01034.20 GAM33595.1 - 2.3 8.2 4.5 8.6 6.4 0.1 3.5 3 0 0 3 3 3 0 Syndecan domain Abhydrolase_3 PF07859.13 GAM33596.1 - 3.6e-41 141.4 0.0 5.9e-41 140.6 0.0 1.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 GAM33596.1 - 4.5e-07 29.1 0.0 1.5e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 GAM33596.1 - 0.0014 17.6 0.0 0.0019 17.1 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Say1_Mug180 PF10340.9 GAM33596.1 - 0.051 12.4 0.1 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 Steryl acetyl hydrolase NmrA PF05368.13 GAM33597.1 - 8.9e-31 107.2 0.1 1.2e-30 106.8 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM33597.1 - 8.9e-21 74.6 0.1 1.1e-20 74.3 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM33597.1 - 1.6e-05 24.5 0.1 3.2e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAM33597.1 - 0.00024 21.3 0.3 0.00042 20.6 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAM33597.1 - 0.00061 19.9 0.4 0.0012 18.9 0.4 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 GAM33597.1 - 0.0049 17.0 0.3 0.013 15.6 0.3 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 GAM33597.1 - 0.0059 15.7 0.2 0.0086 15.2 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 GAM33597.1 - 0.0083 15.5 0.2 0.017 14.5 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 GAM33597.1 - 0.011 16.2 0.8 0.056 13.9 0.3 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAM33597.1 - 0.031 14.5 0.2 0.068 13.3 0.2 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 GAM33597.1 - 0.047 13.1 0.3 0.076 12.5 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 GAM33597.1 - 0.05 12.6 0.1 0.091 11.7 0.1 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ThiF PF00899.21 GAM33597.1 - 0.26 10.6 4.0 0.84 8.9 1.7 2.2 1 1 1 2 2 2 0 ThiF family CDC45 PF02724.14 GAM33598.1 - 0.085 11.1 8.0 0.098 10.9 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GAM33598.1 - 0.11 11.0 4.7 0.11 11.0 4.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFB6 PF17110.5 GAM33598.1 - 0.13 12.0 2.0 0.19 11.5 2.0 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Sigma70_ner PF04546.13 GAM33598.1 - 0.14 12.0 8.3 0.19 11.6 7.9 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.11 GAM33598.1 - 3.3 7.7 9.8 5.2 7.1 9.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Sporozoite_P67 PF05642.11 GAM33598.1 - 3.7 5.5 6.9 4.8 5.1 6.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 GAM33598.1 - 4.9 6.4 21.7 6.6 6.0 21.7 1.1 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 GAM33598.1 - 6.7 6.0 15.9 8.1 5.8 15.9 1.1 1 0 0 1 1 1 0 SDA1 DUF4611 PF15387.6 GAM33598.1 - 8.8 6.6 13.0 22 5.3 13.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CorA PF01544.18 GAM33599.1 - 1.6e-05 24.4 2.0 0.00014 21.3 2.0 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ADP_ribosyl_GH PF03747.14 GAM33601.1 - 1.9e-61 208.4 0.0 2.4e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Pectinesterase PF01095.19 GAM33602.1 - 9.2e-39 132.9 7.7 1.1e-30 106.4 3.3 2.0 1 1 1 2 2 2 2 Pectinesterase Aldolase_II PF00596.21 GAM33603.1 - 1e-45 156.0 0.0 1.3e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain NmrA PF05368.13 GAM33604.1 - 1.3e-13 51.1 0.0 3e-13 49.9 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 GAM33604.1 - 2.9e-11 43.6 0.0 4.4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM33604.1 - 0.00034 20.1 0.0 0.00053 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 GAM33604.1 - 0.0017 18.8 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAM33604.1 - 0.013 15.7 0.0 0.031 14.4 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 GAM33604.1 - 0.026 14.6 0.1 0.04 14.0 0.1 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 GAM33604.1 - 0.029 13.5 0.1 0.049 12.7 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 GAM33604.1 - 0.031 14.2 0.1 0.049 13.6 0.1 1.3 1 0 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 GAM33604.1 - 0.095 12.1 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GAM33604.1 - 0.19 10.8 0.2 0.6 9.2 0.1 1.8 2 0 0 2 2 2 0 Male sterility protein Glyco_transf_8 PF01501.20 GAM33605.1 - 6.9e-22 78.2 1.9 2.9e-20 72.9 1.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GAM33605.1 - 4.7e-05 22.9 0.1 8.7e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative p450 PF00067.22 GAM33606.1 - 1.9e-64 218.1 0.0 3.2e-64 217.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 GAM33607.1 - 4.4e-53 180.8 2.5 5.3e-53 180.5 2.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM33607.1 - 7.7e-19 67.8 7.2 9e-19 67.6 7.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 GAM33607.1 - 0.0014 17.0 1.1 0.0014 17.0 1.1 1.9 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 GAM33607.1 - 0.16 10.3 2.9 0.2 10.0 2.9 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) NAD_binding_10 PF13460.6 GAM33608.1 - 3.5e-29 102.0 1.1 4.3e-29 101.7 1.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM33608.1 - 1.8e-09 37.4 0.1 2e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAM33608.1 - 1.6e-05 24.6 0.2 2.4e-05 24.0 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 GAM33608.1 - 0.021 14.2 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FtsA PF14450.6 GAM33608.1 - 0.022 15.2 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Cell division protein FtsA NAD_binding_4 PF07993.12 GAM33608.1 - 0.045 12.9 0.0 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.19 GAM33608.1 - 0.13 11.3 0.1 0.17 10.8 0.1 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AflR PF08493.10 GAM33609.1 - 1.4e-10 41.1 3.5 2.8e-10 40.2 3.3 1.6 1 1 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 GAM33609.1 - 6.4e-10 39.0 10.2 1.1e-09 38.2 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BNR_2 PF13088.6 GAM33611.1 - 1.2e-19 70.7 0.2 1e-11 44.7 0.3 2.1 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 GAM33611.1 - 9.8e-05 21.8 30.3 0.32 11.2 0.2 6.5 6 0 0 6 6 6 4 BNR/Asp-box repeat BNR_4 PF15892.5 GAM33611.1 - 0.00028 20.3 0.2 0.0023 17.4 0.0 2.2 2 1 0 2 2 2 1 BNR repeat-containing family member Sortilin-Vps10 PF15902.5 GAM33611.1 - 0.0006 18.7 7.8 0.0019 17.0 0.3 3.6 1 1 2 4 4 4 2 Sortilin, neurotensin receptor 3, BNR_3 PF13859.6 GAM33611.1 - 0.0021 17.4 0.2 0.093 12.0 0.2 2.3 1 1 0 1 1 1 1 BNR repeat-like domain CyRPA PF18638.1 GAM33611.1 - 0.033 13.4 3.3 18 4.4 0.0 4.0 3 1 2 5 5 5 0 Cysteine-Rich Protective Antigen 6 bladed domain F5_F8_type_C PF00754.25 GAM33611.1 - 0.061 13.5 10.3 12 6.0 0.1 4.9 1 1 3 5 5 5 0 F5/8 type C domain Carboxyl_trans PF01039.22 GAM33612.1 - 1e-80 271.8 0.0 1.3e-80 271.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 GAM33613.1 - 2.3e-53 180.8 0.0 3.3e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 GAM33613.1 - 2e-31 108.2 0.0 3.6e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 GAM33613.1 - 2.6e-27 95.5 0.0 5.4e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 GAM33613.1 - 1.6e-08 34.3 0.0 4.5e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 GAM33613.1 - 1.4e-06 28.0 0.0 2.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 GAM33613.1 - 0.0002 21.4 0.0 0.00044 20.3 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 GAM33613.1 - 0.0021 17.6 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 GAM33613.1 - 0.0066 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp COesterase PF00135.28 GAM33614.1 - 3.9e-10 39.2 0.0 4.7e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Pyr_redox_2 PF07992.14 GAM33615.1 - 1e-12 47.9 0.0 1.1e-05 24.8 0.0 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM33615.1 - 2.1e-05 23.8 0.2 0.00032 19.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 GAM33615.1 - 0.0011 18.3 0.2 0.13 11.5 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM33615.1 - 0.0021 17.7 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAM33615.1 - 0.0028 16.9 0.0 0.0063 15.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAM33615.1 - 0.0068 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 GAM33615.1 - 0.0072 16.5 0.2 0.021 15.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAM33615.1 - 0.017 14.2 0.1 0.03 13.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 GAM33615.1 - 0.02 14.9 0.3 0.21 11.6 0.2 2.3 1 1 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 GAM33615.1 - 0.023 13.4 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 GAM33615.1 - 0.051 12.6 0.1 0.35 9.9 0.0 2.2 2 1 1 3 3 3 0 Lycopene cyclase protein p450 PF00067.22 GAM33617.1 - 2.1e-44 152.0 0.0 2.7e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 GAM33618.1 - 8.6e-22 78.0 0.1 1.2e-18 67.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM33618.1 - 7.6e-18 65.9 0.4 1.2e-17 65.3 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM33618.1 - 1.9e-10 40.4 0.0 1.5e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 GAM33618.1 - 0.0017 17.2 0.0 0.0025 16.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family p450 PF00067.22 GAM33620.1 - 2e-62 211.5 0.0 2.4e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 GAM33621.1 - 3.2e-05 23.9 0.3 6.3e-05 23.0 0.3 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase COP23 PF14218.6 GAM33621.1 - 0.029 14.1 0.6 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Circadian oscillating protein COP23 Fungal_trans_2 PF11951.8 GAM33625.1 - 0.0047 15.8 0.1 0.0061 15.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 GAM33626.1 - 3.1e-34 118.5 27.3 3.1e-34 118.5 27.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TPT PF03151.16 GAM33627.1 - 7.5e-18 64.9 17.9 3.1e-14 53.0 17.9 2.1 1 1 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GAM33627.1 - 1.8e-06 27.4 16.2 3.2e-05 23.3 8.8 2.3 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 GAM33627.1 - 0.0013 18.9 15.2 0.0013 18.9 15.2 3.5 4 0 0 4 4 4 2 EamA-like transporter family Nucleotid_trans PF03407.16 GAM33628.1 - 1.1e-08 35.3 0.3 1.7e-08 34.7 0.3 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 GAM33628.1 - 1.3e-08 34.8 5.0 9.4e-08 32.1 4.9 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_hydro_31 PF01055.26 GAM33629.1 - 1.7e-144 482.3 6.2 2.2e-144 481.9 6.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 GAM33629.1 - 3.5e-36 123.9 0.0 6.4e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 GAM33629.1 - 1.4e-07 31.7 0.2 4e-07 30.2 0.2 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like ABC_tran PF00005.27 GAM33630.1 - 4.4e-06 27.3 0.0 1.1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 GAM33630.1 - 0.069 13.0 0.3 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 GAM33630.1 - 2.1 8.4 5.1 0.25 11.4 0.6 1.7 2 0 0 2 2 2 0 Dynamin family AP3D1 PF06375.11 GAM33630.1 - 9.2 6.5 7.8 17 5.6 7.8 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 adh_short PF00106.25 GAM33631.1 - 8.3e-23 80.9 0.0 2.5e-19 69.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33631.1 - 5.2e-08 32.7 0.0 1.8e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM33631.1 - 1.1e-06 28.7 0.1 2e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Amidohydro_1 PF01979.20 GAM33632.1 - 4.4e-18 65.7 0.0 3.6e-17 62.7 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM33632.1 - 8.6e-07 28.8 0.0 0.018 14.5 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 GAM33632.1 - 0.018 15.4 0.1 0.039 14.3 0.1 1.5 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Preseq_ALAS PF09029.10 GAM33632.1 - 0.044 14.3 0.0 0.08 13.4 0.0 1.3 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence Sulfatase PF00884.23 GAM33634.1 - 1.6e-66 224.8 1.0 2.6e-66 224.1 1.0 1.4 1 0 0 1 1 1 1 Sulfatase MFS_1 PF07690.16 GAM33634.1 - 2.7e-31 108.8 25.1 4.2e-31 108.2 25.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 GAM33634.1 - 0.015 14.2 4.3 0.028 13.3 3.9 1.5 1 1 0 1 1 1 0 MFS_1 like family MFS_1 PF07690.16 GAM33635.1 - 2.6e-43 148.3 39.1 7.6e-43 146.8 39.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Alginate_lyase PF05426.12 GAM33635.1 - 1.2e-16 61.1 7.9 1.9e-16 60.4 7.9 1.3 1 0 0 1 1 1 1 Alginate lyase TRI12 PF06609.13 GAM33635.1 - 2.4e-11 42.8 12.1 4.5e-10 38.6 13.2 2.4 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 GAM33635.1 - 1.4e-06 27.1 1.3 2.5e-06 26.2 1.3 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector DUF697 PF05128.12 GAM33635.1 - 3 7.5 5.0 18 5.0 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF697) MFS_1 PF07690.16 GAM33636.1 - 4.8e-29 101.4 56.5 8.2e-29 100.6 50.6 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 GAM33636.1 - 2.7e-20 72.9 0.0 4.4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM33636.1 - 4.6e-09 36.0 0.1 7.8e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Sugar_tr PF00083.24 GAM33636.1 - 2.2e-07 30.1 11.6 2.2e-07 30.1 11.6 3.8 4 0 0 4 4 4 1 Sugar (and other) transporter Fungal_trans PF04082.18 GAM33637.1 - 9.8e-11 41.2 0.0 1.6e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 GAM33639.1 - 1.4e-35 122.5 0.1 1.9e-35 122.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33639.1 - 2e-27 96.3 0.0 2.7e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM33639.1 - 1.9e-05 24.7 0.1 2.9e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAM33639.1 - 3.7e-05 23.7 0.1 7e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DFP PF04127.15 GAM33639.1 - 4.9e-05 23.2 0.1 8.2e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein DUF1776 PF08643.10 GAM33639.1 - 0.00092 18.7 0.1 0.0095 15.3 0.1 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 GAM33639.1 - 0.0063 16.0 0.0 0.009 15.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAM33639.1 - 0.019 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Rossmann-like PF10727.9 GAM33639.1 - 0.088 12.7 0.3 0.25 11.2 0.1 1.8 2 0 0 2 2 2 0 Rossmann-like domain FAD_binding_4 PF01565.23 GAM33640.1 - 4.6e-12 45.8 2.1 5.8e-12 45.5 0.6 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAM33640.1 - 2.4e-09 37.1 0.5 2.4e-09 37.1 0.5 1.8 2 0 0 2 2 2 1 Berberine and berberine like DUF5127 PF17168.4 GAM33641.1 - 1.4e-76 257.2 14.5 1.4e-76 257.2 14.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 GAM33641.1 - 3.7e-70 235.1 1.3 3.7e-70 235.1 1.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 GAM33641.1 - 1.8e-61 207.4 2.6 1.8e-61 207.4 2.6 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 GAM33641.1 - 5.8e-09 35.4 0.0 2.3e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) ArabFuran-catal PF09206.11 GAM33642.1 - 4.2e-149 496.1 11.1 5.7e-149 495.7 11.1 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 GAM33642.1 - 1.7e-58 196.6 1.1 2.5e-58 196.0 1.1 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain Pro-kuma_activ PF09286.11 GAM33644.1 - 6.6e-44 149.7 0.0 1.1e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Na_H_Exchanger PF00999.21 GAM33645.1 - 2.6e-59 201.0 49.2 3.6e-59 200.5 49.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family adh_short PF00106.25 GAM33646.1 - 1.8e-28 99.3 0.5 3.8e-27 95.0 0.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33646.1 - 1.8e-19 70.2 0.4 1.5e-18 67.2 0.4 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAM33646.1 - 3.8e-06 26.5 0.1 5.2e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAM33646.1 - 2.9e-05 24.0 0.0 5.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 GAM33646.1 - 0.0033 16.9 0.2 0.0066 15.9 0.2 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAM33646.1 - 0.018 14.9 0.3 0.096 12.6 0.3 2.1 1 1 0 1 1 1 0 NAD(P)H-binding DAHP_snth_FXD PF18152.1 GAM33646.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain Peptidase_S66 PF02016.15 GAM33647.1 - 1.5e-29 102.5 0.0 2e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 GAM33647.1 - 7e-22 78.3 0.0 1e-21 77.7 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain ADH_N PF08240.12 GAM33648.1 - 1.1e-28 99.3 0.5 1.9e-28 98.5 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM33648.1 - 1.9e-14 53.7 0.2 6.5e-13 48.8 0.2 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM33648.1 - 0.00026 22.0 0.0 0.00048 21.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAM33648.1 - 0.021 14.2 0.3 0.032 13.6 0.3 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 GAM33649.1 - 1.4e-55 188.4 0.1 1.6e-55 188.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM33649.1 - 1.9e-46 158.0 0.0 2.4e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM33649.1 - 8.1e-07 29.1 0.1 1.2e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM33649.1 - 1.7e-05 24.5 0.0 3.1e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 GAM33649.1 - 9.5e-05 21.9 0.0 0.00016 21.2 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 GAM33649.1 - 0.00026 20.5 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAM33649.1 - 0.0031 16.7 0.0 0.0042 16.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 GAM33649.1 - 0.005 16.8 0.0 0.097 12.6 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_tranf_2_3 PF13641.6 GAM33650.1 - 3.3e-22 79.5 0.0 4.4e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GAM33650.1 - 5.7e-07 29.2 0.0 1.2e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 GAM33650.1 - 6.3e-05 22.8 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 MFS_1 PF07690.16 GAM33651.1 - 4.2e-30 104.9 42.6 2.2e-29 102.5 42.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM33651.1 - 4.5e-11 41.9 13.9 6.1e-11 41.5 13.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mit_KHE1 PF10173.9 GAM33651.1 - 0.23 11.5 2.3 0.68 10.0 2.3 1.8 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related OATP PF03137.20 GAM33651.1 - 0.24 9.6 8.8 0.015 13.6 2.6 2.0 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family LRR19-TM PF15176.6 GAM33651.1 - 0.87 9.6 2.3 2.7 8.0 0.0 3.1 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain COesterase PF00135.28 GAM33652.1 - 5.1e-57 193.9 0.2 5.8e-57 193.7 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM33652.1 - 7.3e-05 22.7 0.5 0.00039 20.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM33652.1 - 0.19 11.2 0.6 0.3 10.5 0.6 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pectate_lyase_3 PF12708.7 GAM33654.1 - 6.9e-92 307.1 28.5 1.8e-81 273.1 10.7 3.3 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 GAM33654.1 - 3.4e-07 29.8 3.6 0.0076 15.9 0.5 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase ADH_N PF08240.12 GAM33655.1 - 1.1e-26 92.8 0.4 2.1e-26 91.9 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM33655.1 - 4.3e-12 46.1 0.0 6.2e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAM33655.1 - 0.0065 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N_assoc PF13823.6 GAM33655.1 - 0.071 13.1 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated CVNH PF08881.10 GAM33656.1 - 1.3e-11 45.0 0.2 1e-07 32.5 0.1 2.7 2 0 0 2 2 2 2 CVNH domain DUF3153 PF11353.8 GAM33656.1 - 0.091 12.3 0.7 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) Ank_2 PF12796.7 GAM33657.1 - 1.3e-44 150.7 0.0 5.1e-08 33.4 0.3 6.3 5 1 1 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM33657.1 - 3.7e-41 139.0 2.6 1.6e-08 34.9 0.0 9.0 7 2 2 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 GAM33657.1 - 4.1e-37 125.0 8.6 4.1e-05 23.8 0.0 10.2 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 GAM33657.1 - 5.2e-30 100.2 1.1 0.0063 16.9 0.0 10.7 10 2 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 GAM33657.1 - 3.4e-28 97.3 9.0 7.5e-05 22.9 0.0 9.7 6 5 4 10 10 10 6 Ankyrin repeats (many copies) F-box-like PF12937.7 GAM33657.1 - 1.7e-05 24.6 0.0 3.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM33657.1 - 2.1e-05 24.3 0.1 4.7e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAM33657.1 - 0.1 12.5 0.0 0.93 9.4 0.0 2.2 2 0 0 2 2 2 0 F-box Mito_carr PF00153.27 GAM33658.1 - 1.3e-29 101.9 6.1 1.2e-14 54.0 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein Fungal_trans_2 PF11951.8 GAM33659.1 - 1.6e-09 37.1 0.1 2.4e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SIR2_2 PF13289.6 GAM33659.1 - 0.01 16.0 0.1 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 SIR2-like domain HEAT_2 PF13646.6 GAM33659.1 - 0.042 14.2 0.1 3.7 8.0 0.1 3.2 3 1 0 3 3 3 0 HEAT repeats Avl9 PF09794.9 GAM33659.1 - 0.13 11.0 0.1 0.19 10.4 0.1 1.2 1 0 0 1 1 1 0 Transport protein Avl9 ATP_bind_2 PF03668.15 GAM33660.1 - 0.0044 16.4 0.0 0.086 12.1 0.0 2.1 2 0 0 2 2 2 2 P-loop ATPase protein family Peptidase_S28 PF05577.12 GAM33661.1 - 6.2e-41 140.6 2.2 6.6e-40 137.2 2.2 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Transp_cyt_pur PF02133.15 GAM33662.1 - 5.7e-25 88.0 26.7 1e-24 87.2 26.7 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RRN9 PF10680.9 GAM33662.1 - 0.008 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor LptF_LptG PF03739.14 GAM33662.1 - 0.37 9.6 13.8 0.52 9.1 0.0 3.2 3 0 0 3 3 3 0 Lipopolysaccharide export system permease LptF/LptG zf-C2H2 PF00096.26 GAM33663.1 - 6.6e-06 26.3 5.4 0.0053 17.2 0.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM33663.1 - 0.0028 18.3 2.9 0.048 14.5 0.3 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 GAM33663.1 - 0.0046 17.1 0.4 0.0088 16.1 0.4 1.4 1 0 0 1 1 1 1 Zinc ribbon domain zf-BED PF02892.15 GAM33663.1 - 0.27 11.3 2.4 8.7 6.5 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.6 GAM33663.1 - 0.29 11.2 3.6 0.49 10.5 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_hydro_92 PF07971.12 GAM33664.1 - 9.6e-128 427.0 2.1 1.2e-76 258.5 0.8 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 GAM33664.1 - 8.8e-44 150.2 5.9 1.4e-43 149.5 5.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain CUE PF02845.16 GAM33665.1 - 1.7e-07 30.8 0.0 4.6e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 CUE domain Ribosomal_S10 PF00338.22 GAM33666.1 - 2.3e-26 91.9 0.5 2.7e-26 91.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e HNH_2 PF13391.6 GAM33667.1 - 0.002 18.2 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease SMC_N PF02463.19 GAM33669.1 - 3.5e-66 222.8 38.7 2.1e-65 220.2 38.7 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAM33669.1 - 7.4e-24 84.3 0.1 4.6e-23 81.7 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GAM33669.1 - 4.8e-11 43.0 5.0 5.1e-05 23.2 0.3 3.6 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM33669.1 - 6.5e-05 22.6 0.0 0.0019 17.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain CASP_C PF08172.12 GAM33669.1 - 0.0066 15.8 3.2 0.0066 15.8 3.2 7.4 4 2 3 7 7 7 1 CASP C terminal NPV_P10 PF05531.12 GAM33669.1 - 0.094 13.2 0.2 0.094 13.2 0.2 7.3 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein ELYS PF13934.6 GAM33670.1 - 9.3e-65 218.7 3.8 1.1e-64 218.4 3.8 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly Nucleoporin_FG PF13634.6 GAM33671.1 - 0.45 11.4 70.9 0.12 13.2 22.3 4.8 2 1 1 3 3 3 0 Nucleoporin FG repeat region Fungal_trans_2 PF11951.8 GAM33672.1 - 1.1e-46 159.5 2.0 1.9e-46 158.7 2.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM33672.1 - 1.4e-06 28.4 7.1 2.6e-06 27.4 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSG PF02349.15 GAM33672.1 - 0.037 14.2 1.1 0.093 12.9 1.1 1.6 1 0 0 1 1 1 0 Major surface glycoprotein Pkinase PF00069.25 GAM33673.1 - 1.4e-38 132.8 0.0 1.2e-27 96.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ribonuc_2-5A PF06479.12 GAM33673.1 - 5e-32 110.7 0.0 1e-31 109.8 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 GAM33673.1 - 7.8e-20 71.2 0.0 9.8e-19 67.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 GAM33673.1 - 3.4e-05 23.6 0.0 0.12 12.4 0.0 2.9 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.6 GAM33673.1 - 0.0085 15.7 0.1 0.042 13.4 0.1 2.1 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.14 GAM33673.1 - 0.018 14.4 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM33673.1 - 0.024 13.4 0.0 0.05 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase PepSY PF03413.19 GAM33673.1 - 0.14 12.7 0.3 6 7.5 0.0 2.5 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain FAD_binding_3 PF01494.19 GAM33674.1 - 1.5e-18 67.2 0.0 1.3e-10 41.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 GAM33674.1 - 0.0075 16.5 0.0 0.02 15.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF4444 PF14563.6 GAM33674.1 - 0.096 12.4 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) SE PF08491.10 GAM33674.1 - 0.17 10.9 0.0 0.46 9.5 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Aminotran_4 PF01063.19 GAM33675.1 - 6.8e-25 88.2 0.0 8.3e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Draxin PF15550.6 GAM33676.1 - 6.7 6.5 19.9 0.81 9.5 15.3 1.6 2 0 0 2 2 2 0 Draxin SSP160 PF06933.11 GAM33676.1 - 8.1 4.5 6.5 12 3.9 6.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 IF-2B PF01008.17 GAM33677.1 - 2.2e-21 76.3 0.1 6.3e-21 74.8 0.0 1.7 2 0 0 2 2 2 1 Initiation factor 2 subunit family NUDIX PF00293.28 GAM33677.1 - 4.1e-06 26.9 0.1 1.3e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 NUDIX domain DUF3240 PF11582.8 GAM33677.1 - 0.013 15.7 0.0 0.071 13.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3240) Beta-lactamase PF00144.24 GAM33678.1 - 6e-18 65.2 0.0 1.2e-17 64.1 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 GAM33679.1 - 1.2e-41 143.1 0.0 1.7e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 GAM33679.1 - 2.6e-11 43.9 0.0 6.7e-11 42.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) Peptidase_S9 PF00326.21 GAM33680.1 - 2.8e-40 138.1 0.1 4e-40 137.5 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 GAM33680.1 - 7e-12 45.4 0.1 2.9e-11 43.3 0.1 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 GAM33680.1 - 3.2e-08 33.7 0.1 2e-07 31.2 0.1 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 GAM33680.1 - 5.6e-07 29.1 0.3 0.0019 17.5 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 GAM33680.1 - 2.4e-06 27.3 1.1 0.00089 18.9 1.6 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 GAM33680.1 - 2.6e-05 24.2 0.5 0.00039 20.4 0.5 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 GAM33680.1 - 0.00048 20.2 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein SGL PF08450.12 GAM33680.1 - 0.00064 19.4 0.0 0.0038 16.9 0.0 2.2 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Abhydrolase_2 PF02230.16 GAM33680.1 - 0.0024 17.7 0.1 2.3 8.0 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 GAM33680.1 - 0.0032 17.2 0.2 0.84 9.2 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Esterase_phd PF10503.9 GAM33680.1 - 0.0059 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase PD40 PF07676.12 GAM33680.1 - 0.0075 16.2 2.9 0.01 15.8 0.8 2.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat LIP PF03583.14 GAM33680.1 - 0.01 15.2 1.5 3.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Secretory lipase COesterase PF00135.28 GAM33680.1 - 0.02 13.8 0.1 0.037 12.9 0.1 1.3 1 0 0 1 1 1 0 Carboxylesterase family DUF829 PF05705.14 GAM33680.1 - 0.044 13.7 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) FSH1 PF03959.13 GAM33680.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DAO PF01266.24 GAM33681.1 - 3.1e-37 129.0 0.5 3.5e-37 128.8 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAM33681.1 - 1e-05 24.9 0.1 2.5e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 GAM33681.1 - 6e-05 23.2 0.1 0.00015 21.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM33681.1 - 0.00065 18.9 0.0 0.00093 18.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM33681.1 - 0.0012 18.1 0.2 0.0025 17.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM33681.1 - 0.14 11.2 0.1 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein MFS_1 PF07690.16 GAM33682.1 - 1.8e-14 53.5 52.5 2.2e-13 49.9 32.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.12 GAM33682.1 - 0.13 12.4 1.3 2 8.6 0.1 2.9 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Zn_clus PF00172.18 GAM33683.1 - 1.2e-08 34.9 7.1 2.3e-08 34.0 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.6 GAM33684.1 - 6.2e-21 75.8 0.0 1e-20 75.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAM33684.1 - 8.7e-20 71.0 0.0 1.7e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM33684.1 - 0.16 11.9 0.0 2.6 8.0 0.0 2.3 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain LysM PF01476.20 GAM33685.1 - 3.5e-05 23.8 0.1 0.00013 21.9 0.0 2.0 2 0 0 2 2 2 1 LysM domain Nuc_deoxyri_tr3 PF11071.8 GAM33685.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ ThrE PF06738.12 GAM33686.1 - 1e-70 237.8 9.0 3.3e-64 216.5 2.2 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 GAM33686.1 - 7.9e-12 45.4 8.1 7.9e-12 45.4 8.1 3.3 2 1 0 3 3 3 1 Threonine/Serine exporter, ThrE MRAP PF15183.6 GAM33687.1 - 0.55 10.2 3.4 0.73 9.8 0.0 2.4 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Glyco_hydro_20 PF00728.22 GAM33688.1 - 3.9e-97 325.8 0.9 5.2e-97 325.4 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GAM33688.1 - 1.3e-26 93.9 0.4 2.9e-26 92.8 0.4 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 GAM33688.1 - 7.1e-05 23.6 0.2 0.00016 22.4 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 TPR_1 PF00515.28 GAM33689.1 - 6.6e-24 82.7 5.1 2.8e-09 36.4 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAM33689.1 - 6e-23 79.1 5.6 1.5e-07 31.0 0.0 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAM33689.1 - 1e-16 60.3 5.8 1.9e-08 33.9 0.1 5.0 4 2 0 4 4 4 3 TPR repeat TPR_16 PF13432.6 GAM33689.1 - 1.9e-16 60.4 3.4 1.1e-05 26.0 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAM33689.1 - 6.4e-15 54.4 1.9 0.0028 17.9 0.1 5.0 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAM33689.1 - 1e-14 54.0 8.6 3.5e-05 24.3 0.0 6.2 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM33689.1 - 5.5e-14 51.1 2.2 7.4e-07 28.9 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM33689.1 - 2.7e-12 47.0 8.5 0.00023 21.6 0.0 4.8 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM33689.1 - 1.1e-10 40.7 0.9 0.0072 16.3 0.0 5.5 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM33689.1 - 2.7e-10 40.3 0.3 0.0042 17.2 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM33689.1 - 4.1e-10 39.8 6.0 3.5e-06 27.2 0.4 4.2 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 GAM33689.1 - 9.5e-08 32.3 8.0 0.015 15.6 0.1 4.7 4 1 1 5 5 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM33689.1 - 2.4e-05 24.5 3.7 0.0021 18.3 0.5 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAM33689.1 - 6.6e-05 23.3 2.8 2.5 8.9 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAM33689.1 - 9.6e-05 21.7 1.1 0.33 10.1 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 GAM33689.1 - 0.0023 18.0 0.3 10 6.2 0.1 4.3 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 GAM33689.1 - 0.0047 16.9 0.1 4.4 7.4 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF1641 PF07849.11 GAM33689.1 - 0.065 13.1 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) DUF4192 PF13830.6 GAM33689.1 - 0.08 13.0 11.1 0.18 11.8 8.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) TPR_10 PF13374.6 GAM33689.1 - 0.086 12.7 0.3 0.086 12.7 0.3 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF533 PF04391.12 GAM33689.1 - 0.25 10.9 5.3 1.7 8.2 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF533) RRM_1 PF00076.22 GAM33690.1 - 4.2e-34 116.2 0.0 9e-18 63.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.18 GAM33690.1 - 6.3e-12 45.1 0.0 1.4e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM33690.1 - 1.2e-07 31.7 12.4 1.9e-07 31.1 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 GAM33690.1 - 0.021 14.7 0.2 0.05 13.5 0.2 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 ArgoN PF16486.5 GAM33691.1 - 1.2e-18 68.1 0.0 2.1e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute Piwi PF02171.17 GAM33691.1 - 4.7e-15 55.6 0.0 6.7e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 GAM33691.1 - 5e-13 48.5 0.0 1.3e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 GAM33691.1 - 1.1e-09 38.4 0.0 1.6e-08 34.8 0.0 2.7 3 0 0 3 3 3 1 Argonaute linker 2 domain Piwi PF02171.17 GAM33692.1 - 5.6e-47 160.5 0.0 7.9e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain TPR_19 PF14559.6 GAM33693.1 - 0.0059 17.1 0.4 0.49 10.9 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM33693.1 - 0.0081 16.4 0.1 0.03 14.6 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat PPR PF01535.20 GAM33693.1 - 0.013 15.7 0.0 8.2 6.9 0.0 3.2 2 0 0 2 2 2 0 PPR repeat TPR_7 PF13176.6 GAM33693.1 - 0.08 13.0 1.7 3 8.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM33693.1 - 0.081 13.2 0.8 3.9 7.8 0.0 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 GAM33693.1 - 0.11 12.7 0.0 23 5.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAM33693.1 - 0.14 12.8 4.1 0.16 12.7 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Alpha-L-AF_C PF06964.12 GAM33694.1 - 8.3e-28 97.6 0.1 1.7e-27 96.6 0.0 1.5 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain Cellulase PF00150.18 GAM33695.1 - 4.3e-20 72.3 1.0 6.1e-20 71.8 1.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 GAM33695.1 - 5.6e-08 32.6 13.5 5.6e-08 32.6 13.5 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 GAM33695.1 - 0.00044 19.5 0.0 0.00067 18.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 GAM33695.1 - 0.00087 19.0 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) DUF4680 PF15730.5 GAM33695.1 - 0.024 15.0 7.2 2.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) Mucin PF01456.17 GAM33695.1 - 0.08 12.9 17.6 0.14 12.1 17.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 GAM33695.1 - 0.29 9.3 19.0 0.4 8.8 19.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MGC-24 PF05283.11 GAM33695.1 - 2.3 8.7 17.2 0.96 9.9 14.2 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AbiEii PF08843.11 GAM33697.1 - 3.9e-06 27.0 0.0 6e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system DUF2204 PF09970.9 GAM33697.1 - 0.00095 18.9 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) NTP_transf_5 PF14907.6 GAM33697.1 - 0.069 12.8 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase EMC3_TMCO1 PF01956.16 GAM33700.1 - 1.2e-53 181.3 0.5 1.5e-53 181.0 0.5 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like SPC25 PF06703.11 GAM33701.1 - 2e-47 161.0 0.0 2.4e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) SCAB-Ig PF16709.5 GAM33701.1 - 0.036 14.1 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein THF_DHG_CYH PF00763.23 GAM33702.1 - 1.5e-15 57.4 0.6 1e-13 51.6 0.6 2.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 GAM33702.1 - 1.7e-12 46.9 0.1 3.3e-09 36.3 0.0 2.5 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_ab PF00006.25 GAM33703.1 - 1.2e-71 240.8 0.0 1.9e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 GAM33703.1 - 9.9e-49 164.9 1.3 1.8e-48 164.0 1.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 GAM33703.1 - 2.7e-15 56.6 3.4 7.1e-15 55.3 3.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Tex_N PF09371.10 GAM33703.1 - 0.089 12.5 0.1 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 Tex-like protein N-terminal domain DUF962 PF06127.11 GAM33704.1 - 9.3e-26 89.8 0.0 1.6e-25 89.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.17 GAM33705.1 - 2.3e-15 56.7 0.0 4.3e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 GAM33705.1 - 4.4e-09 36.6 0.0 6.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain PBECR3 PF18812.1 GAM33706.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 HMG_box_5 PF14887.6 GAM33706.1 - 0.13 12.3 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Fasciclin PF02469.22 GAM33707.1 - 3.4e-05 24.1 0.0 6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain MMS19_C PF12460.8 GAM33708.1 - 7.8e-122 407.4 16.4 3.4e-121 405.3 9.0 3.6 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 GAM33708.1 - 1.5e-94 316.5 0.8 2.2e-93 312.6 0.0 2.9 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.22 GAM33708.1 - 0.0033 17.6 8.2 2.2 8.7 0.0 5.9 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 GAM33708.1 - 0.021 15.2 8.7 3.5 8.1 0.1 6.1 6 1 0 6 6 6 0 HEAT repeats HEAT_EZ PF13513.6 GAM33708.1 - 0.028 14.9 14.8 4.3 7.9 0.6 5.9 5 0 0 5 5 5 0 HEAT-like repeat Cnd1 PF12717.7 GAM33708.1 - 9.7 6.2 10.1 0.84 9.7 0.2 4.0 6 0 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 SHE3 PF17078.5 GAM33710.1 - 4.9e-06 26.4 28.5 0.012 15.3 20.2 2.2 1 1 1 2 2 2 2 SWI5-dependent HO expression protein 3 TolA_bind_tri PF16331.5 GAM33710.1 - 0.021 14.9 1.6 0.021 14.9 1.6 3.7 2 1 1 3 3 3 0 TolA binding protein trimerisation ZapB PF06005.12 GAM33710.1 - 0.04 14.4 4.0 0.04 14.4 4.0 4.4 2 1 0 2 2 1 0 Cell division protein ZapB Jnk-SapK_ap_N PF09744.9 GAM33710.1 - 0.047 13.9 32.2 0.65 10.2 19.6 2.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FlxA PF14282.6 GAM33710.1 - 0.049 13.6 24.0 0.056 13.4 5.4 3.4 1 1 2 3 3 3 0 FlxA-like protein Spc7 PF08317.11 GAM33710.1 - 0.34 9.7 36.7 0.39 9.5 16.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 GAM33710.1 - 0.39 10.8 37.3 0.63 10.1 14.1 3.3 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Lebercilin PF15619.6 GAM33710.1 - 2.1 7.9 39.3 17 5.0 17.2 2.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ERM PF00769.19 GAM33710.1 - 4.2 7.1 38.5 1.4 8.6 15.0 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HrpB7 PF09486.10 GAM33710.1 - 6.4 7.1 31.0 11 6.4 20.7 3.3 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Snapin_Pallidin PF14712.6 GAM33710.1 - 7.3 7.1 20.9 1.2 9.6 1.0 3.7 3 1 1 4 4 4 0 Snapin/Pallidin GPI-anchored PF10342.9 GAM33711.1 - 1.8e-13 51.0 0.1 1.8e-13 51.0 0.1 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CBF PF03914.17 GAM33712.1 - 3.4e-37 128.1 1.4 7.4e-37 127.0 1.4 1.6 1 0 0 1 1 1 1 CBF/Mak21 family Mt_ATP-synt_B PF05405.14 GAM33713.1 - 1.1e-52 177.9 5.4 1.6e-52 177.5 5.4 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Virul_Fac PF10139.9 GAM33713.1 - 0.0094 14.2 1.8 0.012 13.8 1.8 1.1 1 0 0 1 1 1 1 Putative bacterial virulence factor DUF1539 PF07560.11 GAM33713.1 - 0.015 15.4 0.2 0.026 14.6 0.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) V_ATPase_I PF01496.19 GAM33713.1 - 0.33 8.8 2.2 0.4 8.5 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF932 PF06067.11 GAM33713.1 - 1.2 8.8 5.0 3.3 7.4 5.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF932) Sel1 PF08238.12 GAM33714.1 - 1.1e-13 51.4 5.7 5.4e-05 23.7 0.1 3.8 4 0 0 4 4 4 3 Sel1 repeat FmdA_AmdA PF03069.15 GAM33715.1 - 3.2e-174 579.1 0.0 3.7e-174 578.9 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family RCC1 PF00415.18 GAM33716.1 - 1.3e-54 182.6 4.5 4.4e-12 46.4 0.1 7.4 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM33716.1 - 2.1e-42 142.1 24.3 3.4e-10 39.5 1.1 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat U79_P34 PF03064.16 GAM33716.1 - 2.7 7.3 9.4 6.9 6.0 9.2 1.7 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Presenilin PF01080.17 GAM33716.1 - 3 6.5 6.8 4 6.1 6.8 1.1 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 GAM33717.1 - 4.6e-31 108.0 36.8 4.6e-31 108.0 36.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM33718.1 - 1.6e-11 43.8 0.2 1.6e-11 43.8 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM33718.1 - 5e-08 32.9 6.7 8.4e-08 32.2 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 GAM33719.1 - 2.6e-07 30.6 13.1 2.6e-07 30.6 13.1 2.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAM33719.1 - 4.5e-06 26.6 6.6 4.5e-06 26.6 6.6 2.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAM33719.1 - 8.9e-05 22.9 13.4 8.9e-05 22.9 13.4 3.7 2 1 2 4 4 4 1 bZIP Maf transcription factor DUF4854 PF16146.5 GAM33719.1 - 0.15 12.4 3.1 4.3 7.7 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4854) JAKMIP_CC3 PF16034.5 GAM33719.1 - 0.73 9.8 18.5 2 8.3 18.5 1.7 1 0 0 1 1 1 0 JAKMIP CC3 domain DUF334 PF03904.13 GAM33719.1 - 9 5.8 17.2 68 2.9 16.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF334) zf-CCCH PF00642.24 GAM33720.1 - 0.0016 18.3 3.7 1.5 8.8 0.1 3.3 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 GAM33720.1 - 0.38 11.3 2.6 0.67 10.5 0.7 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DNA_pol_phi PF04931.13 GAM33720.1 - 0.86 7.6 6.4 1.4 6.9 6.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi bZIP_1 PF00170.21 GAM33721.1 - 1.8e-09 37.5 13.0 2.8e-09 36.9 13.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAM33721.1 - 0.00047 20.2 12.0 0.00077 19.5 12.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper OmpH PF03938.14 GAM33721.1 - 0.0012 19.2 7.7 0.0016 18.8 7.7 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) bZIP_Maf PF03131.17 GAM33721.1 - 0.0061 17.1 13.8 0.0096 16.4 13.8 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Kinesin_assoc PF16183.5 GAM33721.1 - 0.029 14.5 0.1 0.038 14.1 0.1 1.2 1 0 0 1 1 1 0 Kinesin-associated ZapB PF06005.12 GAM33721.1 - 0.031 14.7 4.4 0.031 14.7 4.4 1.7 2 0 0 2 2 2 0 Cell division protein ZapB Presenilin PF01080.17 GAM33721.1 - 0.037 12.8 1.9 0.047 12.5 1.9 1.1 1 0 0 1 1 1 0 Presenilin GAS PF13851.6 GAM33721.1 - 0.041 13.2 7.9 0.06 12.7 7.9 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 GAM33721.1 - 0.076 13.1 4.5 0.1 12.7 4.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TipAS PF07739.13 GAM33721.1 - 0.08 13.5 2.3 0.12 12.9 2.3 1.3 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain FapA PF03961.13 GAM33721.1 - 0.086 11.4 0.8 0.11 11.1 0.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Seryl_tRNA_N PF02403.22 GAM33721.1 - 1.1 9.5 6.4 1.8 8.8 6.2 1.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Fungal_trans_2 PF11951.8 GAM33722.1 - 3.1e-08 32.9 4.3 5.4e-08 32.1 0.7 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain UPF0259 PF06790.11 GAM33722.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0259) TFIIF_beta_N PF17683.1 GAM33723.1 - 3.9e-32 111.8 0.9 5.8e-32 111.2 0.3 1.6 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 GAM33723.1 - 1.5e-25 89.1 0.3 3.1e-25 88.1 0.3 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 GAM33723.1 - 0.015 16.1 1.7 0.063 14.1 1.6 2.0 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain PCI PF01399.27 GAM33724.1 - 3.6e-12 46.7 0.0 7.7e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 GAM33724.1 - 1.9e-05 24.4 0.1 4e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 Herpes_UL14 PF03580.14 GAM33724.1 - 0.0029 17.9 1.0 2.1 8.6 0.1 2.6 1 1 1 2 2 2 2 Herpesvirus UL14-like protein TPR_19 PF14559.6 GAM33724.1 - 5 7.7 12.3 1.1 9.9 1.6 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat HET PF06985.11 GAM33725.1 - 0.0033 17.8 0.2 0.16 12.3 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FAD_binding_2 PF00890.24 GAM33726.1 - 2.6e-84 283.7 0.4 3.3e-84 283.4 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 GAM33726.1 - 1.2e-21 76.6 0.1 1.1e-19 70.3 0.0 3.2 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 GAM33726.1 - 4.6e-14 52.8 0.3 8.8e-14 51.8 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAM33726.1 - 1.9e-09 37.4 2.0 7.4e-09 35.5 2.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM33726.1 - 3.2e-08 33.2 0.7 3.8e-07 29.6 0.4 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM33726.1 - 3.5e-08 33.6 1.7 1e-07 32.0 0.2 2.5 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM33726.1 - 1.1e-06 28.1 0.1 0.012 14.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM33726.1 - 2.7e-06 26.3 4.7 9.7e-05 21.2 2.0 3.1 2 1 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 GAM33726.1 - 3.5e-05 23.2 0.2 5.8e-05 22.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAM33726.1 - 0.00012 21.4 0.5 0.03 13.6 0.1 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 GAM33726.1 - 0.00062 19.0 2.4 0.18 10.9 0.5 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 GAM33726.1 - 0.0037 16.6 0.9 2 7.6 0.1 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 GAM33726.1 - 0.018 15.0 3.0 0.57 10.2 3.0 2.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAM33726.1 - 0.022 15.3 2.8 5.3 7.7 0.2 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAM33726.1 - 0.054 12.8 0.2 0.11 11.8 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4914 PF16260.5 GAM33726.1 - 0.16 10.0 0.0 0.22 9.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4914) Dicty_REP PF05086.12 GAM33727.1 - 0.67 7.9 5.0 0.97 7.3 5.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4674 PF15719.5 GAM33727.1 - 1.9 8.5 9.7 4.3 7.3 9.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) WD40 PF00400.32 GAM33728.1 - 9.7e-13 48.4 2.8 0.12 13.3 0.3 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM33728.1 - 0.01 16.1 0.2 2.9 8.2 0.0 3.7 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Sin3a_C PF16879.5 GAM33729.1 - 1.4e-78 264.5 6.9 1.4e-78 264.5 6.9 2.8 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 GAM33729.1 - 6.2e-47 157.5 2.4 1.1e-17 63.8 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 GAM33729.1 - 1.3e-38 131.0 0.1 3.9e-38 129.5 0.1 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor TSP_NTD PF17804.1 GAM33729.1 - 0.012 15.9 1.6 0.012 15.9 1.6 3.3 4 0 0 4 4 4 0 Tail specific protease N-terminal domain RhoGEF67_u2 PF16614.5 GAM33729.1 - 0.19 11.8 0.3 22 5.2 0.0 2.7 2 0 0 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 AcetylCoA_hydro PF02550.15 GAM33730.1 - 2.1e-49 168.2 0.0 3.1e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 GAM33730.1 - 1.9e-43 148.1 0.0 2.8e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain bZIP_1 PF00170.21 GAM33731.1 - 0.018 15.1 6.5 0.037 14.1 6.5 1.4 1 0 0 1 1 1 0 bZIP transcription factor Glutaredoxin2_C PF04399.13 GAM33731.1 - 0.086 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain TFIIA PF03153.13 GAM33731.1 - 0.6 10.0 12.1 1 9.2 12.1 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Alpha_GJ PF03229.13 GAM33732.1 - 0.011 16.3 0.5 0.016 15.8 0.5 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J Beta-lactamase PF00144.24 GAM33733.1 - 5.5e-52 177.0 0.0 7.3e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase COesterase PF00135.28 GAM33735.1 - 2.1e-93 313.9 0.0 4.7e-93 312.8 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Ank_2 PF12796.7 GAM33735.1 - 1.8e-73 243.1 10.5 1.6e-14 54.3 0.4 10.0 3 3 4 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM33735.1 - 1.9e-56 187.7 12.1 7.5e-10 39.1 0.0 14.3 5 4 12 17 17 17 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM33735.1 - 2.3e-45 147.3 27.1 6.7e-05 23.0 0.0 20.4 21 0 0 21 21 21 8 Ankyrin repeat Ank PF00023.30 GAM33735.1 - 4.5e-30 102.7 47.1 2.1e-05 24.8 0.2 18.1 19 0 0 19 19 19 9 Ankyrin repeat Ank_5 PF13857.6 GAM33735.1 - 6.4e-22 77.3 23.3 0.12 12.8 0.0 13.1 9 3 4 13 13 13 7 Ankyrin repeats (many copies) Clr5 PF14420.6 GAM33735.1 - 2.1e-15 56.7 2.1 2.4e-15 56.5 0.6 2.0 2 0 0 2 2 2 1 Clr5 domain Abhydrolase_3 PF07859.13 GAM33735.1 - 8.1e-05 22.6 0.1 0.00042 20.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM33735.1 - 0.058 12.9 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family NmrA PF05368.13 GAM33736.1 - 5e-18 65.5 0.0 8e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM33736.1 - 1.7e-14 54.1 0.0 3e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 GAM33736.1 - 5.9e-05 23.2 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 GAM33736.1 - 8.4e-05 22.1 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM33736.1 - 0.0034 16.4 0.0 0.0061 15.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GFO_IDH_MocA PF01408.22 GAM33736.1 - 0.011 16.5 0.1 0.035 14.9 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold KR PF08659.10 GAM33736.1 - 0.047 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 KR domain F420_oxidored PF03807.17 GAM33736.1 - 0.19 12.3 0.7 0.5 11.0 0.7 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_17 PF00332.18 GAM33739.1 - 0.0061 16.2 2.9 0.011 15.3 1.9 1.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 MFS_1 PF07690.16 GAM33742.1 - 1.6e-25 89.8 50.6 1.1e-24 87.0 50.2 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM33742.1 - 2.8e-09 35.9 19.8 3.8e-09 35.5 19.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 GAM33742.1 - 0.36 9.1 11.7 0.01 14.3 2.5 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.20 GAM33742.1 - 2.6 6.2 13.5 0.57 8.4 0.8 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans_2 PF11951.8 GAM33743.1 - 1.5e-06 27.3 0.2 0.00032 19.6 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain ADH_zinc_N PF00107.26 GAM33744.1 - 1.9e-14 53.7 6.2 2e-12 47.2 3.2 2.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM33744.1 - 3.7e-14 53.9 0.6 8.8e-14 52.7 0.6 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM33744.1 - 3e-08 33.5 0.0 6.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PPR_3 PF13812.6 GAM33744.1 - 0.033 14.2 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 Pentatricopeptide repeat domain WD40 PF00400.32 GAM33745.1 - 0.00054 20.7 1.6 0.0085 16.9 0.1 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF5329 PF17263.2 GAM33745.1 - 0.014 15.6 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5329) MFS_1 PF07690.16 GAM33746.1 - 4e-36 124.7 48.8 4.2e-35 121.3 48.8 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Cation_ATPase_C PF00689.21 GAM33746.1 - 0.003 17.3 4.9 0.003 17.3 4.9 3.1 2 2 1 3 3 3 1 Cation transporting ATPase, C-terminus ABM PF03992.16 GAM33747.1 - 0.01 15.9 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Epimerase PF01370.21 GAM33750.1 - 1.9e-11 43.9 0.1 4.2e-11 42.8 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM33750.1 - 3.3e-10 40.1 0.1 4.9e-10 39.6 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM33750.1 - 1.3e-09 38.0 0.0 2.7e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 GAM33750.1 - 6e-06 25.9 0.1 1.6e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAM33750.1 - 0.00077 18.5 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAM33750.1 - 0.00079 18.6 0.2 0.0043 16.2 0.2 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAM33750.1 - 0.00081 18.6 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 GAM33750.1 - 0.0011 18.5 0.1 0.0023 17.4 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.24 GAM33750.1 - 0.0066 16.9 0.1 0.27 11.7 0.0 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAM33750.1 - 0.019 15.1 0.0 0.037 14.2 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 GAM33750.1 - 0.029 13.5 0.0 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 GAM33750.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glyco_hydro_43 PF04616.14 GAM33751.1 - 6.4e-104 347.3 1.5 3.5e-103 344.9 0.6 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 GAM33751.1 - 2.2e-48 164.7 0.0 3.1e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain adh_short PF00106.25 GAM33752.1 - 3.6e-35 121.2 0.1 5.2e-35 120.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33752.1 - 4.1e-22 78.9 0.0 5.8e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM33752.1 - 8.1e-10 38.9 0.0 1.1e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM33752.1 - 0.00027 20.2 0.1 0.00037 19.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein FerI PF08151.12 GAM33752.1 - 0.092 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 FerI (NUC094) domain Eno-Rase_NADH_b PF12242.8 GAM33752.1 - 0.098 12.4 0.5 0.18 11.6 0.5 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Lipase_GDSL_2 PF13472.6 GAM33753.1 - 2.8e-14 53.9 0.1 4.8e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAM33753.1 - 0.021 14.8 0.1 0.081 12.9 0.1 2.0 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Lip_prot_lig_C PF10437.9 GAM33753.1 - 0.096 12.7 0.0 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus Glyco_hydro_67M PF07488.12 GAM33754.1 - 7.1e-137 455.8 0.0 1e-136 455.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 GAM33754.1 - 1.3e-89 299.6 2.2 1.6e-89 299.2 1.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 GAM33754.1 - 1.9e-23 83.0 0.0 3.4e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 GAM33754.1 - 0.023 15.5 0.0 0.045 14.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 Sugar_tr PF00083.24 GAM33755.1 - 6e-83 279.2 21.3 6.9e-83 279.0 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM33755.1 - 3.9e-12 45.8 36.9 1.1e-06 27.9 23.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mo-co_dimer PF03404.16 GAM33755.1 - 0.047 13.7 0.1 0.099 12.7 0.1 1.5 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Tannase PF07519.11 GAM33756.1 - 2.1e-116 389.6 2.8 2.5e-116 389.4 2.8 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 GAM33756.1 - 0.026 14.2 0.2 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM33756.1 - 0.13 11.5 0.0 0.67 9.2 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_M61 PF05299.12 GAM33757.1 - 0.0029 18.0 1.3 0.017 15.6 1.3 2.1 1 1 0 1 1 1 1 M61 glycyl aminopeptidase Peptidase_M1 PF01433.20 GAM33757.1 - 0.0073 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Sugar_tr PF00083.24 GAM33758.1 - 1.9e-67 228.1 26.8 2.2e-67 227.9 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM33758.1 - 4.1e-11 42.4 31.2 4.1e-11 42.4 31.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 GAM33758.1 - 0.002 16.8 21.1 0.056 12.0 5.0 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Ank_2 PF12796.7 GAM33759.1 - 4.4e-74 245.1 5.9 4e-15 56.2 0.0 7.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM33759.1 - 5e-55 183.2 15.5 1.8e-08 34.8 0.1 9.3 3 2 7 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM33759.1 - 6.9e-54 173.5 7.7 1.5e-05 25.0 0.1 13.1 13 0 0 13 13 13 11 Ankyrin repeat Ank PF00023.30 GAM33759.1 - 1.9e-51 170.4 20.4 0.00018 21.8 0.0 12.9 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 GAM33759.1 - 5.9e-51 169.9 20.8 7e-08 32.6 0.0 11.1 1 1 11 12 12 12 11 Ankyrin repeats (many copies) F-box-like PF12937.7 GAM33759.1 - 0.00027 20.8 0.1 0.00054 19.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like Nitrate_red_gam PF02665.14 GAM33759.1 - 0.069 12.7 0.1 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 Nitrate reductase gamma subunit Tox-REase-2 PF15646.6 GAM33761.1 - 0.02 15.1 1.0 0.051 13.8 0.6 1.8 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 2 Chitin_synth_2 PF03142.15 GAM33762.1 - 3.3e-292 969.8 0.0 4.4e-292 969.4 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 GAM33762.1 - 4.1e-13 49.7 2.6 1.7e-12 47.7 2.6 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAM33762.1 - 4.4e-11 43.1 0.0 1.1e-09 38.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAM33762.1 - 0.00018 21.3 0.0 0.018 14.9 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAM33762.1 - 0.00029 20.4 0.0 0.0047 16.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 AveC_like PF17198.4 GAM33762.1 - 0.0051 16.3 0.2 0.0051 16.3 0.2 2.3 2 0 0 2 2 2 1 Spirocyclase AveC-like CSS-motif PF12792.7 GAM33762.1 - 0.11 12.0 0.3 0.24 10.9 0.3 1.5 1 0 0 1 1 1 0 CSS motif domain associated with EAL Sel1 PF08238.12 GAM33763.1 - 6.6e-35 118.8 27.2 9.4e-06 26.1 1.8 7.4 7 0 0 7 7 7 7 Sel1 repeat Fungal_trans PF04082.18 GAM33764.1 - 1.6e-09 37.2 0.3 2.9e-09 36.4 0.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM33764.1 - 0.00012 22.1 14.6 0.00022 21.3 14.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 GAM33765.1 - 1.4e-35 122.5 0.0 4.2e-35 121.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33765.1 - 2e-26 93.0 0.0 4.6e-26 91.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM33765.1 - 1e-08 35.3 0.3 9.3e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAM33765.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AraC_binding PF02311.19 GAM33766.1 - 0.0024 17.8 0.2 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 GAM33766.1 - 0.047 13.4 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Cupin domain MFS_1 PF07690.16 GAM33767.1 - 1e-35 123.3 31.6 1e-35 123.3 31.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2628 PF10947.8 GAM33767.1 - 9 6.7 8.4 0.88 10.0 2.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2628) FAD_binding_3 PF01494.19 GAM33768.1 - 7.7e-23 81.3 0.0 1.2e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM33768.1 - 0.054 13.7 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF917 PF06032.12 GAM33769.1 - 1.1e-116 389.5 0.2 3.8e-115 384.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 GAM33769.1 - 5.9e-28 97.8 1.5 2.1e-27 96.0 0.3 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 GAM33769.1 - 5.9e-26 91.4 8.0 1.2e-23 83.9 1.7 3.2 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 GAM33769.1 - 0.0024 17.4 0.0 0.037 13.5 0.2 2.5 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 GAM33769.1 - 0.0036 16.0 1.8 0.047 12.3 0.3 2.5 2 0 0 2 2 2 1 MutL protein ROK PF00480.20 GAM33769.1 - 0.056 12.9 0.2 0.13 11.7 0.2 1.6 1 0 0 1 1 1 0 ROK family adh_short PF00106.25 GAM33770.1 - 1.7e-36 125.5 1.1 2.3e-36 125.1 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33770.1 - 1.7e-27 96.5 1.7 2.2e-27 96.1 1.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM33770.1 - 2.5e-19 69.9 0.6 3.5e-19 69.4 0.6 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM33770.1 - 2.7e-08 33.3 0.1 3.3e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAM33770.1 - 4.4e-07 29.6 0.3 1.2e-06 28.2 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LDcluster4 PF18306.1 GAM33770.1 - 0.046 13.3 0.5 0.089 12.4 0.5 1.4 1 0 0 1 1 1 0 SLOG cluster4 family Shikimate_DH PF01488.20 GAM33770.1 - 0.047 13.7 0.4 0.26 11.3 0.4 2.1 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 GAM33771.1 - 1.7e-26 92.7 0.0 1.1e-19 70.5 0.0 3.6 4 0 0 4 4 4 3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DHHC PF01529.20 GAM33772.1 - 0.054 13.6 0.3 0.076 13.1 0.3 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase HATPase_c_3 PF13589.6 GAM33773.1 - 1.2e-13 51.1 0.1 2.9e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 GAM33773.1 - 5.6e-12 45.4 0.0 1.4e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 GAM33773.1 - 4.3e-08 33.6 0.0 9.8e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ndc1_Nup PF09531.10 GAM33774.1 - 1.9 7.1 10.4 2.1 6.9 10.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.25 GAM33775.1 - 1.8e-68 230.7 0.0 3.1e-68 230.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM33775.1 - 2.7e-44 151.4 0.0 4.5e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 GAM33775.1 - 8.5e-08 32.3 0.0 0.021 15.0 0.0 3.1 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 GAM33775.1 - 2e-06 27.4 0.0 4.1e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAM33775.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OPA3 PF07047.12 GAM33776.1 - 8.4e-49 164.5 4.2 1.3e-48 163.9 4.2 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Med11 PF10280.9 GAM33776.1 - 0.012 16.1 1.2 0.029 14.8 1.2 1.7 1 0 0 1 1 1 0 Mediator complex protein BatD PF13584.6 GAM33776.1 - 0.35 9.6 6.3 0.017 13.9 0.8 1.6 2 0 0 2 2 2 0 Oxygen tolerance APG6_N PF17675.1 GAM33776.1 - 8.5 6.9 16.3 1.6 9.2 4.1 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Sld5 PF05916.11 GAM33777.1 - 0.16 12.4 0.2 0.56 10.7 0.2 1.9 1 1 0 1 1 1 0 GINS complex protein Myosin_head PF00063.21 GAM33778.1 - 6.5e-240 798.0 6.4 7.8e-240 797.7 6.4 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 GAM33778.1 - 9.9e-52 175.3 0.0 1.9e-51 174.4 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 GAM33778.1 - 3.9e-13 48.8 0.0 1e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAM33778.1 - 4.3e-08 32.7 0.0 1.7e-07 30.8 0.0 2.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAM33778.1 - 1.1e-06 28.4 0.0 3.3e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.6 GAM33778.1 - 0.013 15.8 0.0 0.042 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain IQ PF00612.27 GAM33778.1 - 0.03 14.1 9.7 1 9.3 1.0 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_16 PF13191.6 GAM33778.1 - 0.036 14.5 0.0 0.092 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 GAM33778.1 - 0.075 12.5 3.1 2.8 7.4 0.0 2.9 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain NACHT PF05729.12 GAM33778.1 - 0.19 11.6 0.0 0.47 10.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Cation_efflux PF01545.21 GAM33779.1 - 6.5e-53 179.4 10.3 2.5e-52 177.5 10.3 1.8 1 1 0 1 1 1 1 Cation efflux family DUF3613 PF12266.8 GAM33779.1 - 0.12 12.1 0.3 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) Cupin_1 PF00190.22 GAM33780.1 - 2.7e-39 134.2 0.0 2e-20 72.9 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 GAM33780.1 - 4.4e-22 77.6 0.0 1.4e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 GAM33780.1 - 2.5e-08 33.5 0.0 0.0088 15.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 GAM33780.1 - 6e-05 23.0 0.1 0.0011 18.9 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_6 PF12852.7 GAM33780.1 - 0.00098 18.9 0.0 0.27 10.9 0.0 2.3 2 0 0 2 2 2 2 Cupin MannoseP_isomer PF01050.18 GAM33780.1 - 0.0044 16.9 0.0 0.082 12.8 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.12 GAM33780.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase ARD PF03079.14 GAM33780.1 - 0.13 12.5 0.0 0.48 10.6 0.0 1.8 2 0 0 2 2 2 0 ARD/ARD' family Cupin_4 PF08007.12 GAM33780.1 - 0.18 11.2 0.0 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein Helo_like_N PF17111.5 GAM33781.1 - 0.00017 21.0 3.0 0.00032 20.1 3.0 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF2852 PF11014.8 GAM33781.1 - 0.00078 19.6 0.1 0.0018 18.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2852) FPP PF05911.11 GAM33781.1 - 0.0017 16.7 6.1 0.0025 16.1 6.1 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil RasGAP_C PF03836.15 GAM33781.1 - 0.0034 17.5 6.7 0.0087 16.2 6.7 1.7 1 1 0 1 1 1 1 RasGAP C-terminus Herpes_UL6 PF01763.16 GAM33781.1 - 0.0056 15.3 1.7 0.0086 14.7 1.7 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like Macoilin PF09726.9 GAM33781.1 - 0.022 13.3 10.9 0.039 12.5 10.9 1.3 1 0 0 1 1 1 0 Macoilin family DLP_helical PF18709.1 GAM33781.1 - 0.041 13.1 0.5 0.079 12.1 0.5 1.4 1 0 0 1 1 1 0 Dynamin-like helical domain ATG16 PF08614.11 GAM33781.1 - 0.044 14.0 8.7 0.56 10.4 8.3 2.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FliD_C PF07195.12 GAM33781.1 - 0.057 12.8 2.5 0.086 12.2 0.2 2.2 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Atg14 PF10186.9 GAM33781.1 - 0.059 12.4 7.0 0.1 11.6 7.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Trimer_CC PF08954.11 GAM33781.1 - 0.073 12.6 0.1 0.5 10.0 0.1 2.5 2 0 0 2 2 1 0 Trimerisation motif Prominin PF05478.11 GAM33781.1 - 0.073 11.0 2.0 0.11 10.4 2.0 1.2 1 0 0 1 1 1 0 Prominin FlaC_arch PF05377.11 GAM33781.1 - 0.1 13.0 1.6 1.2 9.6 0.6 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) GCN5L1 PF06320.13 GAM33781.1 - 0.16 12.2 1.9 0.18 12.0 0.3 1.8 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Tmemb_cc2 PF10267.9 GAM33781.1 - 0.18 10.9 6.6 0.54 9.3 6.6 1.8 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Fez1 PF06818.15 GAM33781.1 - 0.31 11.5 9.2 0.18 12.3 7.0 1.7 2 0 0 2 2 1 0 Fez1 OmpH PF03938.14 GAM33781.1 - 0.4 11.0 4.5 0.73 10.2 4.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 GAM33781.1 - 0.58 10.3 7.7 0.13 12.5 1.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FapA PF03961.13 GAM33781.1 - 0.6 8.7 1.5 0.9 8.1 1.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A STAT_alpha PF01017.20 GAM33781.1 - 0.76 9.7 7.3 0.59 10.0 5.2 1.8 2 0 0 2 2 2 0 STAT protein, all-alpha domain CorA PF01544.18 GAM33781.1 - 0.87 8.8 7.2 0.55 9.5 3.5 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein MscS_porin PF12795.7 GAM33781.1 - 0.91 9.0 8.5 3.2 7.2 8.5 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain TMF_TATA_bd PF12325.8 GAM33781.1 - 1.4 9.1 9.1 0.97 9.7 5.8 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Lzipper-MIP1 PF14389.6 GAM33781.1 - 1.9 8.9 9.8 3.7 7.9 0.1 3.2 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 UPF0242 PF06785.11 GAM33781.1 - 2 8.5 10.1 2.2 8.3 6.9 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 GAM33781.1 - 2.4 7.6 8.9 0.29 10.7 4.4 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit GrpE PF01025.19 GAM33781.1 - 4.5 6.9 6.6 9.3 5.9 1.1 2.3 1 1 0 2 2 2 0 GrpE Cep57_MT_bd PF06657.13 GAM33781.1 - 5.6 7.5 8.2 0.26 11.8 0.9 2.5 3 0 0 3 3 2 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.15 GAM33781.1 - 6.1 6.7 6.2 2.2 8.1 0.4 2.7 2 0 0 2 2 2 0 Septum formation initiator FlxA PF14282.6 GAM33781.1 - 6.8 6.7 13.2 0.15 12.0 0.4 2.7 3 0 0 3 3 2 0 FlxA-like protein PRKG1_interact PF15898.5 GAM33781.1 - 9.8 7.1 9.7 13 6.7 2.1 2.7 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Acetyltransf_3 PF13302.7 GAM33783.1 - 2.9e-11 44.2 0.0 4.7e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAM33783.1 - 0.021 15.0 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Epimerase PF01370.21 GAM33784.1 - 5.6e-15 55.5 0.0 1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM33784.1 - 2.6e-13 49.6 0.0 8.8e-13 47.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAM33784.1 - 8.8e-09 35.5 0.1 4.7e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 GAM33784.1 - 2.7e-06 26.7 0.1 0.00022 20.5 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 GAM33784.1 - 9.5e-06 25.2 0.0 4.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAM33784.1 - 2.9e-05 23.7 0.2 0.0014 18.2 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 GAM33784.1 - 0.00015 21.0 0.0 0.00025 20.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 GAM33784.1 - 0.0044 16.5 0.1 0.019 14.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Aldedh PF00171.22 GAM33785.1 - 3.5e-125 418.1 0.0 5.1e-125 417.6 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M20 PF01546.28 GAM33785.1 - 6e-30 104.5 0.2 1.9e-29 102.9 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM33785.1 - 1.9e-09 37.4 0.0 5.4e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAM33785.1 - 0.009 15.7 0.0 0.017 14.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 PilJ_C PF18223.1 GAM33785.1 - 0.088 13.3 0.0 0.28 11.7 0.0 1.8 1 0 0 1 1 1 0 Pili PilJ C-terminal domain Choline_kin_N PF04428.14 GAM33785.1 - 0.17 11.6 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 Choline kinase N terminus Abhydro_lipase PF04083.16 GAM33786.1 - 2.9e-21 74.8 0.0 5.9e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 GAM33786.1 - 9.3e-08 32.0 0.1 3.4e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM33786.1 - 0.01 15.2 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 GAM33786.1 - 0.16 10.9 0.0 0.81 8.6 0.0 1.9 1 1 0 1 1 1 0 Chlorophyllase enzyme Phosphoesterase PF04185.14 GAM33787.1 - 7.1e-62 209.7 1.9 1.3e-61 208.8 1.9 1.4 1 1 0 1 1 1 1 Phosphoesterase family Fungal_trans PF04082.18 GAM33788.1 - 0.00049 19.2 0.1 0.001 18.2 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM33788.1 - 0.016 15.4 5.5 0.021 14.9 4.3 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DLP_helical PF18709.1 GAM33788.1 - 0.037 13.2 0.8 0.54 9.4 0.7 2.1 2 0 0 2 2 2 0 Dynamin-like helical domain Lactamase_B PF00753.27 GAM33789.1 - 0.0022 18.0 0.3 0.0033 17.5 0.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Malate_synthase PF01274.22 GAM33789.1 - 0.15 10.3 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 Malate synthase Lactamase_B PF00753.27 GAM33790.1 - 4.9e-09 36.5 0.1 5.5e-09 36.3 0.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM33790.1 - 5.5e-06 26.0 0.0 6.3e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAM33790.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase superfamily domain 4HBT_3 PF13622.6 GAM33791.1 - 2.2e-41 142.8 0.3 2.7e-41 142.5 0.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily bZIP_1 PF00170.21 GAM33792.1 - 1.2e-05 25.3 2.3 2.1e-05 24.5 2.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF4988 PF16378.5 GAM33792.1 - 0.2 11.3 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function Abhydrolase_3 PF07859.13 GAM33793.1 - 7.1e-23 81.6 0.0 1.1e-22 80.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAM33793.1 - 8.5e-18 64.3 0.0 1.3e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 GAM33793.1 - 0.046 14.3 0.2 0.12 12.9 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family LPAM_1 PF08139.12 GAM33793.1 - 1.1 9.9 6.4 0.66 10.6 0.4 3.1 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site adh_short_C2 PF13561.6 GAM33794.1 - 2.3e-45 155.0 2.7 8.2e-45 153.2 2.7 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM33794.1 - 3.9e-34 117.8 2.8 5e-33 114.2 2.8 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM33794.1 - 4e-07 30.1 2.0 1.1e-06 28.6 2.0 1.7 1 1 0 1 1 1 1 KR domain Dak1_2 PF13684.6 GAM33794.1 - 0.011 14.8 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family THF_DHG_CYH_C PF02882.19 GAM33794.1 - 0.027 13.8 0.9 0.082 12.2 0.9 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NupH_GANP PF16768.5 GAM33794.1 - 0.088 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin homology of Germinal-centre associated nuclear protein 3HCDH_N PF02737.18 GAM33794.1 - 0.11 12.4 0.6 0.17 11.7 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 GAM33794.1 - 0.12 11.7 0.0 4.1 6.7 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase CDH-cyt PF16010.5 GAM33795.1 - 1.1e-26 93.6 0.2 2.1e-26 92.7 0.2 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 GAM33795.1 - 2.7e-05 24.3 8.2 6.2e-05 23.1 8.2 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 GAM33795.1 - 0.11 12.3 5.6 0.22 11.3 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF4231 PF14015.6 GAM33795.1 - 0.18 12.3 3.4 2.3 8.7 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF508 PF04370.12 GAM33795.1 - 4.1 7.1 6.0 8.5 6.1 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Cupredoxin_1 PF13473.6 GAM33796.1 - 0.04 14.0 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain Tyrosinase PF00264.20 GAM33797.1 - 2.2e-54 185.1 2.0 2.2e-54 185.1 2.0 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 GAM33797.1 - 1.5e-25 90.2 0.0 2.4e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Metallophos PF00149.28 GAM33798.1 - 5.7e-08 33.5 0.8 1.1e-07 32.6 0.8 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase eIF-3_zeta PF05091.12 GAM33799.1 - 3.6e-210 699.4 0.0 4.4e-210 699.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) bZIP_1 PF00170.21 GAM33800.1 - 0.003 17.6 11.7 0.0088 16.1 11.5 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAM33800.1 - 0.011 15.8 11.6 0.11 12.6 5.1 2.3 2 0 0 2 2 2 0 Basic region leucine zipper HemX PF04375.14 GAM33800.1 - 0.018 14.3 0.5 0.028 13.7 0.5 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase HMMR_N PF15905.5 GAM33800.1 - 0.15 11.5 6.8 0.045 13.2 2.0 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Aminopep PF10023.9 GAM33800.1 - 0.45 9.8 3.4 0.7 9.2 3.4 1.2 1 0 0 1 1 1 0 Putative aminopeptidase TEX13 PF15186.6 GAM33800.1 - 1.6 8.4 5.2 2.6 7.7 5.2 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family BicD PF09730.9 GAM33801.1 - 0.0074 14.8 1.7 0.01 14.3 1.7 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D DUF4635 PF15466.6 GAM33801.1 - 0.13 11.7 0.4 1.6 8.3 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4635) PEP_mutase PF13714.6 GAM33802.1 - 3.5e-58 196.9 1.1 3.9e-58 196.7 1.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Radical_SAM PF04055.21 GAM33802.1 - 0.016 15.5 0.0 3.1 8.1 0.0 2.6 1 1 1 2 2 2 0 Radical SAM superfamily MFS_1 PF07690.16 GAM33803.1 - 7.3e-18 64.6 63.9 8.8e-12 44.6 42.4 3.5 2 1 1 3 3 3 2 Major Facilitator Superfamily SLATT_1 PF18181.1 GAM33803.1 - 0.21 11.5 0.6 8.8 6.3 0.1 3.4 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 YoqO PF14037.6 GAM33803.1 - 0.29 11.7 8.8 0.56 10.8 5.8 3.0 2 1 0 2 2 2 0 YoqO-like protein MFS_1 PF07690.16 GAM33804.1 - 2.4e-40 138.5 27.8 2.4e-40 138.5 27.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM33804.1 - 2.6e-13 49.6 4.0 2.6e-13 49.6 4.0 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter BT1 PF03092.16 GAM33804.1 - 1.2e-05 23.8 5.6 1.2e-05 23.8 5.6 1.6 2 0 0 2 2 2 1 BT1 family Tail_VII PF17091.5 GAM33804.1 - 0.13 12.2 2.1 0.35 10.8 0.2 2.9 2 0 0 2 2 2 0 Inovirus G7P protein NADHdh_A3 PF14987.6 GAM33804.1 - 1.2 9.5 4.3 0.28 11.5 0.2 2.1 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 TMEM43 PF07787.12 GAM33804.1 - 3.3 7.0 4.9 1.8 7.9 0.3 2.6 3 0 0 3 3 3 0 Transmembrane protein 43 MFS_1 PF07690.16 GAM33805.1 - 1.9e-41 142.2 54.9 2.3e-40 138.6 54.9 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_A14 PF05767.12 GAM33805.1 - 0.05 13.8 3.6 0.13 12.4 2.7 2.2 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 NmrA PF05368.13 GAM33806.1 - 1.2e-43 149.4 0.0 1.5e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM33806.1 - 5.4e-25 88.3 0.0 1.1e-24 87.4 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 GAM33806.1 - 2.8e-09 36.8 0.2 6.8e-09 35.5 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM33806.1 - 2.5e-06 27.2 0.0 3.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAM33806.1 - 6.9e-06 25.4 0.2 2.3e-05 23.6 0.2 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAM33806.1 - 3.7e-05 23.0 0.1 0.0066 15.7 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 GAM33806.1 - 6e-05 22.6 0.1 0.0002 20.9 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.19 GAM33806.1 - 0.00082 18.5 0.1 0.0024 17.0 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N PF00107.26 GAM33806.1 - 0.012 15.6 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase KR PF08659.10 GAM33806.1 - 0.047 13.6 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 KR domain HTH_56 PF18662.1 GAM33806.1 - 0.076 13.1 0.0 0.56 10.3 0.0 2.2 2 0 0 2 2 2 0 Cch helix turn helix domain AMP-binding PF00501.28 GAM33807.1 - 2.5e-52 177.9 1.4 4.9e-52 176.9 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme DUF1772 PF08592.11 GAM33807.1 - 3.8e-23 82.3 0.9 9.4e-23 81.0 0.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) HisKA_7TM PF16927.5 GAM33807.1 - 0.0095 16.0 2.9 0.022 14.8 2.9 1.5 1 0 0 1 1 1 1 N-terminal 7TM region of histidine kinase DUF998 PF06197.13 GAM33807.1 - 0.36 10.4 3.1 0.72 9.4 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Lactococcin PF04369.13 GAM33807.1 - 0.82 9.8 2.7 37 4.6 0.1 3.0 3 0 0 3 3 3 0 Lactococcin-like family EthD PF07110.11 GAM33808.1 - 4.8e-20 72.5 2.7 6.8e-20 72.0 2.7 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 GAM33808.1 - 1.6e-05 25.3 1.4 2.1e-05 24.9 0.4 1.8 2 0 0 2 2 2 1 Methylmuconolactone methyl-isomerase p47_phox_C PF08944.11 GAM33808.1 - 0.043 13.2 1.8 0.083 12.3 1.8 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain ketoacyl-synt PF00109.26 GAM33809.1 - 3e-73 246.5 0.0 5.5e-73 245.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 GAM33809.1 - 1.4e-47 162.4 0.0 2.5e-45 155.1 0.0 3.3 2 1 1 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 GAM33809.1 - 5.2e-38 131.3 0.0 1e-37 130.3 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM33809.1 - 8e-34 116.2 0.5 2.5e-33 114.6 0.5 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 GAM33809.1 - 6.3e-11 42.5 1.3 1.7e-10 41.1 1.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 GAM33809.1 - 4.8e-09 36.7 0.1 1.7e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 GAM33809.1 - 6.9e-09 35.4 0.0 1.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 GAM33809.1 - 0.00015 21.2 0.1 0.00036 20.0 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Raf1_HTH PF18579.1 GAM33809.1 - 0.16 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Aldo_ket_red PF00248.21 GAM33810.1 - 2.7e-61 207.4 0.0 3.4e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_2 PF00891.18 GAM33811.1 - 7.6e-27 94.0 0.0 1.3e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 GAM33811.1 - 0.0088 16.0 0.0 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain Raf1_HTH PF18579.1 GAM33811.1 - 0.027 14.1 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain Cu-oxidase_3 PF07732.15 GAM33812.1 - 8.8e-41 138.7 7.9 1.8e-40 137.6 2.7 3.5 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAM33812.1 - 6.9e-38 129.5 10.7 8.6e-36 122.7 0.3 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 GAM33812.1 - 5.1e-31 107.9 0.1 2.4e-29 102.5 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase GMC_oxred_N PF00732.19 GAM33813.1 - 9.3e-53 179.5 0.0 1.2e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM33813.1 - 8.3e-32 110.7 0.1 1.4e-31 110.0 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 GAM33813.1 - 2.7e-06 26.8 0.1 0.0002 20.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM33813.1 - 2.2e-05 23.7 0.6 3.4e-05 23.1 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAM33813.1 - 4.9e-05 22.7 0.0 0.00057 19.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM33813.1 - 9.3e-05 22.6 0.6 0.00024 21.3 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM33813.1 - 0.00019 21.1 0.4 0.00076 19.2 0.0 2.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAM33813.1 - 0.00045 19.6 0.1 0.00075 18.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 GAM33813.1 - 0.00047 20.4 0.1 0.0018 18.5 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain HI0933_like PF03486.14 GAM33813.1 - 0.0031 16.3 0.9 0.006 15.3 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Transglycosylas PF06737.14 GAM33813.1 - 0.022 15.4 0.2 0.97 10.1 0.0 2.8 2 0 0 2 2 2 0 Transglycosylase-like domain FAD_binding_2 PF00890.24 GAM33813.1 - 0.032 13.3 0.1 0.056 12.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 GAM33813.1 - 0.034 13.4 0.1 0.071 12.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 GAM33813.1 - 0.042 14.4 0.1 0.37 11.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAM33813.1 - 0.061 12.7 0.3 0.55 9.5 0.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM33813.1 - 0.064 13.3 0.1 0.21 11.6 0.1 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_DMAT PF11991.8 GAM33814.1 - 2e-100 336.7 0.0 2.3e-100 336.5 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase adh_short PF00106.25 GAM33815.1 - 5.5e-39 133.7 0.1 6.8e-39 133.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33815.1 - 2.8e-33 115.4 0.0 3.6e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM33815.1 - 3.5e-12 46.6 0.0 4.9e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM33815.1 - 1.7e-05 24.1 0.0 3.2e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAM33815.1 - 0.0044 16.5 0.0 0.033 13.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Questin_oxidase PF14027.6 GAM33816.1 - 3.3e-91 306.3 0.5 3.9e-91 306.1 0.5 1.0 1 0 0 1 1 1 1 Questin oxidase-like DUF732 PF05305.14 GAM33816.1 - 0.087 13.2 0.8 4.3 7.8 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF732) Lactamase_B_5 PF14597.6 GAM33816.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily NAD_binding_10 PF13460.6 GAM33817.1 - 9.4e-16 58.2 0.0 1.2e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM33817.1 - 6.4e-09 35.7 0.0 1.5e-08 34.5 0.0 1.6 1 1 1 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 GAM33817.1 - 0.00023 20.3 0.1 0.00028 20.0 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 GAM33817.1 - 0.0067 17.0 0.0 0.014 16.0 0.0 1.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 GAM33817.1 - 0.021 15.3 0.0 0.035 14.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 GAM33817.1 - 0.047 12.8 0.0 0.088 12.0 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein Epimerase PF01370.21 GAM33817.1 - 0.057 12.9 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM33817.1 - 0.15 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ABM PF03992.16 GAM33818.1 - 0.0021 18.1 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase p450 PF00067.22 GAM33819.1 - 8.3e-51 173.2 0.0 1.5e-39 136.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Herpes_IE68 PF02479.16 GAM33819.1 - 0.0018 17.9 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus immediate early protein PEGSRP PF07623.11 GAM33819.1 - 0.19 11.5 0.0 0.49 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) adh_short PF00106.25 GAM33820.1 - 7.3e-36 123.5 0.0 1.6e-35 122.4 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33820.1 - 4.1e-24 85.4 0.0 5.8e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM33820.1 - 1.4e-11 44.7 0.0 1.8e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM33820.1 - 1.6e-05 24.5 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM33820.1 - 2.9e-05 23.4 0.0 6.3e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 GAM33820.1 - 7e-05 22.8 0.2 8.4e-05 22.5 0.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAM33820.1 - 0.00092 18.7 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GAM33820.1 - 0.0094 15.1 0.1 0.021 14.0 0.1 1.5 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 GAM33820.1 - 0.038 13.1 0.1 0.063 12.4 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 GAM33820.1 - 0.077 13.6 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DFP PF04127.15 GAM33820.1 - 0.15 11.8 0.5 0.65 9.8 0.5 1.8 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Lactamase_B PF00753.27 GAM33821.1 - 7.3e-15 55.5 4.8 1.1e-13 51.7 4.8 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM33821.1 - 0.0001 21.9 0.6 0.00018 21.1 0.6 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 GAM33821.1 - 0.00098 19.1 0.5 0.0048 16.8 0.0 2.5 3 0 0 3 3 3 1 Beta-lactamase associated winged helix domain DUF3181 PF11378.8 GAM33821.1 - 0.17 12.2 0.1 0.36 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) adh_short_C2 PF13561.6 GAM33822.1 - 2.2e-50 171.4 0.5 3.1e-50 170.9 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM33822.1 - 3.8e-44 150.5 0.8 5.5e-44 150.0 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM33822.1 - 1.6e-05 24.9 0.4 2.8e-05 24.1 0.4 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAM33822.1 - 0.033 13.6 0.0 0.042 13.2 0.0 1.4 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) ORC2 PF04084.14 GAM33822.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 2 AflR PF08493.10 GAM33823.1 - 1.1e-53 182.6 16.4 2.1e-53 181.7 16.4 1.4 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 GAM33823.1 - 9.3e-08 32.1 9.9 1.6e-07 31.3 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DASH_Dad2 PF08654.10 GAM33823.1 - 0.38 11.2 1.9 5.9 7.4 0.0 2.6 3 0 0 3 3 3 0 DASH complex subunit Dad2 Transferase PF02458.15 GAM33824.1 - 6.4e-23 81.1 0.0 3.3e-18 65.6 0.0 2.0 2 0 0 2 2 2 2 Transferase family Scytalone_dh PF02982.14 GAM33826.1 - 1.4e-71 239.4 1.9 1.6e-71 239.3 1.9 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 GAM33826.1 - 2.9e-10 40.4 0.6 3.3e-10 40.2 0.6 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 GAM33826.1 - 0.016 15.4 1.9 0.19 12.0 1.9 2.1 1 1 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.6 GAM33826.1 - 0.026 14.9 1.7 1.2 9.6 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4440) DHDPS PF00701.22 GAM33828.1 - 4.8e-41 140.4 0.0 5.6e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Aminotran_1_2 PF00155.21 GAM33829.1 - 9.1e-54 183.0 0.0 1e-53 182.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FMO-like PF00743.19 GAM33830.1 - 2.1e-16 59.5 1.0 5.3e-15 54.8 0.2 2.6 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAM33830.1 - 1.9e-08 33.9 0.0 4.5e-06 26.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAM33830.1 - 1.5e-05 24.4 0.0 0.0002 20.7 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM33830.1 - 5.1e-05 23.4 1.3 6.2e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM33830.1 - 0.00015 21.1 0.0 0.0037 16.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM33830.1 - 0.078 13.0 0.1 3.2 7.7 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Hydantoinase_B PF02538.14 GAM33831.1 - 7.1e-211 701.1 0.1 8.9e-211 700.8 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 GAM33831.1 - 2.6e-101 338.7 0.0 4.8e-101 337.9 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GAM33831.1 - 5.3e-56 189.1 0.1 8.3e-54 182.0 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.9 GAM33831.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature DUF3546 PF12066.8 GAM33832.1 - 3.8e-31 107.5 3.5 3.8e-31 107.5 3.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 GAM33832.1 - 1.5e-12 47.1 0.1 3.7e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 GAM33832.1 - 4.5e-09 37.0 15.2 4.7e-08 33.6 15.2 2.7 1 1 0 1 1 1 1 Arsenite-resistance protein 2 DUF1122 PF06557.11 GAM33832.1 - 1.7 8.1 4.4 2 7.8 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1122) CBFB_NFYA PF02045.15 GAM33833.1 - 1.5e-28 99.2 4.6 3e-28 98.2 4.6 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.13 GAM33833.1 - 0.0011 19.0 25.5 0.0013 18.8 25.5 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Hus1 PF04005.12 GAM33833.1 - 0.046 12.8 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein Glyco_hydro_43 PF04616.14 GAM33834.1 - 4e-66 223.3 3.9 5.6e-66 222.8 3.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 GAM33834.1 - 2.6e-20 73.0 0.0 4.3e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain ABC_tran PF00005.27 GAM33835.1 - 8e-53 178.6 0.3 3.3e-32 111.9 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 GAM33835.1 - 1e-30 107.3 25.8 8.3e-21 74.8 9.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GAM33835.1 - 2.2e-10 40.3 1.9 0.00039 19.9 0.0 4.2 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM33835.1 - 0.00052 19.7 0.3 0.75 9.6 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 GAM33835.1 - 0.00053 20.1 0.9 0.11 12.6 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 GAM33835.1 - 0.00097 19.4 0.2 1.4 9.1 0.1 3.3 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 GAM33835.1 - 0.0011 19.0 0.1 0.062 13.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM33835.1 - 0.0011 18.9 0.7 1.7 8.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 GAM33835.1 - 0.0016 19.0 0.1 0.89 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 GAM33835.1 - 0.005 16.6 0.0 0.089 12.5 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase T2SSE PF00437.20 GAM33835.1 - 0.0077 15.3 0.2 2.3 7.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 GAM33835.1 - 0.013 15.1 0.4 9.8 5.7 0.0 3.4 3 1 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 GAM33835.1 - 0.016 15.4 0.0 3.8 7.8 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 GAM33835.1 - 0.017 15.5 0.1 2.9 8.2 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 GAM33835.1 - 0.018 14.8 0.1 4.9 6.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAM33835.1 - 0.062 12.5 1.4 0.38 9.9 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 GAM33835.1 - 0.066 13.2 0.1 5.9 6.9 0.0 2.9 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_21 PF13304.6 GAM33835.1 - 0.098 12.4 1.2 2.2 8.0 0.1 3.2 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system TrwB_AAD_bind PF10412.9 GAM33835.1 - 0.099 11.5 0.3 1.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 GAM33835.1 - 0.11 12.2 1.9 2.9 7.6 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein CEP209_CC5 PF16574.5 GAM33835.1 - 0.14 12.4 0.5 0.27 11.4 0.5 1.4 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 NACHT PF05729.12 GAM33835.1 - 0.18 11.7 3.1 0.74 9.7 0.0 2.9 3 0 0 3 3 3 0 NACHT domain RNA_helicase PF00910.22 GAM33835.1 - 0.2 12.1 0.1 40 4.6 0.0 2.9 3 0 0 3 3 2 0 RNA helicase NmrA PF05368.13 GAM33836.1 - 1.1e-21 77.5 0.0 1.3e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM33836.1 - 5e-16 59.1 0.0 7.1e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM33836.1 - 6.5e-06 25.8 0.0 0.0028 17.1 0.1 3.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAM33836.1 - 0.02 15.1 0.1 0.084 13.1 0.2 2.1 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 GAM33836.1 - 0.034 14.3 0.1 0.068 13.3 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 GAM33836.1 - 0.087 13.3 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAM33836.1 - 0.16 12.0 0.0 0.61 10.1 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.23 GAM33836.1 - 0.17 12.0 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain TPR_12 PF13424.6 GAM33837.1 - 2.4e-21 75.8 0.6 2.9e-09 37.1 0.2 4.2 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAM33837.1 - 1.2e-14 53.7 3.5 0.002 17.9 0.1 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAM33837.1 - 1.3e-12 46.8 0.0 0.39 11.1 0.0 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 GAM33837.1 - 2.8e-11 43.1 0.0 8.3e-11 41.6 0.0 1.8 2 0 0 2 2 2 1 Phosphorylase superfamily TPR_14 PF13428.6 GAM33837.1 - 9.6e-10 38.5 0.3 2.8 9.0 0.0 6.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM33837.1 - 7.3e-08 31.9 0.2 3.5 7.9 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM33837.1 - 2e-07 31.4 6.1 0.1 13.1 0.1 4.5 2 1 3 5 5 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM33837.1 - 3.1e-07 30.5 0.5 0.27 11.5 0.0 5.5 3 1 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 GAM33837.1 - 1.4e-06 28.0 0.4 14 6.1 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAM33837.1 - 2.8e-06 27.6 5.0 0.23 11.8 0.1 4.7 1 1 3 4 4 4 1 Tetratricopeptide repeat DUF4248 PF14053.6 GAM33837.1 - 2e-05 24.5 0.0 14 5.8 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4248) PPR PF01535.20 GAM33837.1 - 2.7e-05 24.1 1.1 58 4.3 0.0 6.1 6 0 0 6 6 6 0 PPR repeat TPR_6 PF13174.6 GAM33837.1 - 0.00012 22.4 0.0 1.9 9.3 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM33837.1 - 0.00017 22.2 2.3 4.6 8.0 0.0 4.4 4 1 1 5 5 4 1 Tetratricopeptide repeat SPO22 PF08631.10 GAM33837.1 - 0.00037 20.1 0.5 0.002 17.7 0.2 2.3 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like ATG16 PF08614.11 GAM33837.1 - 0.0012 19.1 3.1 0.5 10.6 1.1 2.5 1 1 0 2 2 2 2 Autophagy protein 16 (ATG16) VWA_3_C PF18571.1 GAM33837.1 - 0.0032 17.3 6.2 23 5.0 0.1 4.4 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain PPR_2 PF13041.6 GAM33837.1 - 0.04 14.1 0.4 64 3.9 0.0 4.3 5 0 0 5 5 4 0 PPR repeat family DUF1593 PF07632.11 GAM33838.1 - 9.1e-73 244.9 0.0 1.2e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 GAM33838.1 - 0.033 13.0 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 REJ domain ADH_N PF08240.12 GAM33839.1 - 1.1e-30 105.7 0.4 1.8e-30 105.0 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM33839.1 - 4e-13 49.5 0.0 6.7e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAM33839.1 - 7.2e-07 28.9 0.0 2.3e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAM33839.1 - 0.068 14.2 0.0 0.13 13.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 GAM33839.1 - 0.089 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 GAM33839.1 - 0.13 11.4 0.5 1.8 7.7 0.0 2.4 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAM33839.1 - 0.19 11.0 0.6 0.5 9.6 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.18 GAM33840.1 - 3.9e-05 22.8 0.0 9.3e-05 21.6 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain SHR3_chaperone PF08229.11 GAM33840.1 - 0.21 10.5 0.0 0.41 9.6 0.0 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 MFS_1 PF07690.16 GAM33841.1 - 5.9e-23 81.4 42.3 5.9e-23 81.4 42.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PRIMA1 PF16101.5 GAM33841.1 - 0.15 12.1 0.1 0.65 10.0 0.0 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 UL40 PF10682.9 GAM33841.1 - 0.16 11.6 2.4 0.14 11.9 0.6 1.7 2 0 0 2 2 2 0 Glycoprotein of human cytomegalovirus HHV-5 Aldo_ket_red PF00248.21 GAM33842.1 - 4.4e-46 157.4 0.0 6.3e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 GAM33843.1 - 1.3e-08 34.8 9.6 2.4e-08 34.0 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAM33844.1 - 1.2e-14 53.9 2.0 2.5e-14 52.9 2.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain MIT PF04212.18 GAM33844.1 - 0.12 12.5 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Sugar_tr PF00083.24 GAM33845.1 - 2.9e-73 247.3 20.5 3.4e-73 247.1 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM33845.1 - 1.4e-16 60.4 32.9 1.4e-16 60.4 32.9 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM33846.1 - 1.5e-78 264.7 19.6 1.9e-78 264.4 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM33846.1 - 2e-35 122.4 36.4 1.7e-33 116.0 18.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM33846.1 - 9e-05 21.1 0.9 9e-05 21.1 0.9 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 GAM33846.1 - 0.00025 19.7 3.5 0.00025 19.7 3.5 2.4 3 0 0 3 3 3 1 MFS/sugar transport protein Phage_holin_3_2 PF04550.12 GAM33846.1 - 0.036 14.6 0.6 0.1 13.1 0.6 1.7 1 0 0 1 1 1 0 Phage holin family 2 UPF0239 PF06783.11 GAM33846.1 - 0.083 13.1 0.4 3.4 7.9 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) Kinesin PF00225.23 GAM33847.1 - 1.2e-107 359.7 0.0 2.2e-107 358.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 GAM33847.1 - 3.7e-45 154.3 0.1 9.8e-45 153.0 0.1 1.8 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 GAM33847.1 - 1.6e-37 129.4 11.2 2e-31 109.5 0.2 3.3 3 1 1 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 GAM33847.1 - 2.6e-23 82.6 0.0 9.7e-23 80.8 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding FHA PF00498.26 GAM33847.1 - 8.3e-07 29.3 0.1 7.6e-06 26.2 0.1 2.8 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 GAM33847.1 - 1.3e-06 28.7 0.2 5.9e-06 26.6 0.1 2.3 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.29 GAM33847.1 - 4.1e-06 27.2 0.0 1.7e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 PH domain AAA_22 PF13401.6 GAM33847.1 - 0.055 13.7 0.2 1 9.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF334 PF03904.13 GAM33847.1 - 0.15 11.5 4.2 0.69 9.4 4.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF334) UPF0242 PF06785.11 GAM33847.1 - 2.5 8.2 14.2 4.1 7.5 0.6 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DAPG_hydrolase PF18089.1 GAM33848.1 - 3e-21 76.0 0.0 2.1e-20 73.3 0.0 1.9 1 1 0 1 1 1 1 DAPG hydrolase PhiG domain Pkinase PF00069.25 GAM33849.1 - 2.3e-08 33.7 0.0 3.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 GAM33849.1 - 3e-05 23.5 0.0 4.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM33849.1 - 0.00039 20.4 0.0 0.00073 19.5 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family MFS_1 PF07690.16 GAM33850.1 - 1.8e-26 93.0 18.3 1.8e-26 93.0 18.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM33850.1 - 3.1e-10 39.5 5.4 3.1e-10 39.5 5.4 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Sugar_tr PF00083.24 GAM33851.1 - 9.7e-80 268.6 30.2 1.1e-79 268.4 30.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM33851.1 - 2e-21 76.3 33.9 2e-21 76.3 33.9 2.3 1 1 2 3 3 3 3 Major Facilitator Superfamily Melibiase PF02065.18 GAM33852.1 - 6.8e-36 123.9 0.0 9e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 GAM33852.1 - 3.5e-08 33.3 0.1 6.1e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Melibiase_2 PF16499.5 GAM33852.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha galactosidase A RPN6_C_helix PF18503.1 GAM33852.1 - 0.14 11.9 0.4 0.27 11.0 0.4 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain Fungal_trans PF04082.18 GAM33853.1 - 1e-09 37.8 0.0 1.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4693 PF15764.5 GAM33853.1 - 0.023 14.3 0.1 0.035 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4693) MMS1_N PF10433.9 GAM33853.1 - 0.16 10.6 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term COesterase PF00135.28 GAM33855.1 - 3.7e-84 283.4 0.0 4.6e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM33855.1 - 0.00017 21.5 0.1 0.00052 19.9 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM33855.1 - 0.03 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family NUP PF06516.11 GAM33856.1 - 1.3e-64 218.4 0.0 1.6e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) PqqD PF05402.12 GAM33856.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) NmrA PF05368.13 GAM33857.1 - 4.7e-27 95.0 0.0 8.6e-22 77.8 0.0 2.2 1 1 1 2 2 2 2 NmrA-like family Xan_ur_permease PF00860.20 GAM33857.1 - 2.2e-22 79.3 31.8 5.8e-21 74.6 30.3 2.8 2 1 0 2 2 2 1 Permease family NAD_binding_10 PF13460.6 GAM33857.1 - 0.00011 22.2 0.0 0.00035 20.5 0.0 1.7 1 1 1 2 2 2 1 NAD(P)H-binding DUF543 PF04418.12 GAM33857.1 - 0.98 9.4 0.0 0.98 9.4 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF543) Glyco_transf_90 PF05686.12 GAM33858.1 - 1.1e-27 97.0 0.4 1.7e-27 96.4 0.4 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 DNase_NucA_NucB PF14040.6 GAM33858.1 - 8.3e-08 32.6 0.1 2.6e-07 31.0 0.1 1.8 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Glyco_trans_1_2 PF13524.6 GAM33858.1 - 0.031 14.6 0.0 0.075 13.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 AAL_decarboxy PF03306.13 GAM33858.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase APH PF01636.23 GAM33859.1 - 1.5e-14 54.5 0.0 2.1e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM33859.1 - 4e-12 46.2 0.0 4.5e-11 42.7 0.0 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 GAM33859.1 - 0.011 15.1 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain BCS1_N PF08740.11 GAM33860.1 - 2.6e-49 167.8 1.2 4.3e-49 167.0 1.2 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 GAM33860.1 - 4.9e-17 62.6 0.0 6.3e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM33860.1 - 0.0015 19.0 0.0 0.0035 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain TALPID3 PF15324.6 GAM33860.1 - 0.0039 15.0 1.7 0.0057 14.4 1.7 1.2 1 0 0 1 1 1 1 Hedgehog signalling target DUF815 PF05673.13 GAM33860.1 - 0.0041 16.3 0.0 0.0079 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 GAM33860.1 - 0.037 13.6 0.0 0.098 12.2 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 GAM33860.1 - 0.12 12.3 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAM33860.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAM33860.1 - 0.14 12.7 0.0 1.1 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Glyco_hydro_43 PF04616.14 GAM33861.1 - 2.1e-34 119.2 0.0 2.8e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Na_H_Exchanger PF00999.21 GAM33862.1 - 3.3e-35 121.6 33.7 2.7e-29 102.1 24.2 3.0 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family PetM PF08041.11 GAM33862.1 - 0.065 12.8 0.8 0.31 10.6 0.8 2.3 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 Epiglycanin_C PF14654.6 GAM33862.1 - 0.39 10.8 2.2 3.8 7.6 0.1 2.8 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Methyltransf_2 PF00891.18 GAM33863.1 - 4.4e-26 91.5 0.0 6.8e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 GAM33863.1 - 0.0036 18.0 0.0 0.039 14.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain CobT_C PF11775.8 GAM33863.1 - 0.042 13.5 0.1 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain Methyltransf_12 PF08242.12 GAM33863.1 - 0.14 12.9 0.0 0.52 11.1 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 GAM33864.1 - 5.4e-37 127.5 64.0 6.4e-36 124.0 62.1 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily AflR PF08493.10 GAM33865.1 - 1.1e-06 28.4 0.9 1.1e-06 28.4 0.9 1.7 1 1 0 1 1 1 1 Aflatoxin regulatory protein ketoacyl-synt PF00109.26 GAM33866.1 - 4.6e-80 268.8 0.0 1.1e-79 267.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 GAM33866.1 - 5.9e-51 173.5 0.2 7e-50 170.0 0.0 2.8 3 1 1 4 4 4 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 GAM33866.1 - 4.6e-38 131.5 0.0 4.2e-37 128.3 0.0 2.3 3 0 0 3 3 3 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM33866.1 - 8.2e-33 112.9 0.3 1.9e-32 111.7 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 GAM33866.1 - 6e-26 91.1 0.0 9.6e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 GAM33866.1 - 6.4e-21 74.5 8.9 5.5e-10 39.5 1.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 GAM33866.1 - 3e-09 36.5 0.0 5.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 GAM33866.1 - 3.5e-07 30.7 0.0 1.2e-06 28.9 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 GAM33866.1 - 1.4e-05 24.6 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.21 GAM33866.1 - 0.001 18.6 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM33866.1 - 0.0048 16.1 0.0 0.048 12.8 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 GAM33866.1 - 0.028 14.3 0.0 0.068 13.1 0.0 1.7 1 0 0 1 1 1 0 KR domain Questin_oxidase PF14027.6 GAM33867.1 - 5.9e-91 305.5 0.0 7.3e-91 305.2 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Methyltransf_11 PF08241.12 GAM33869.1 - 2e-07 31.6 0.0 4.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM33869.1 - 7.4e-06 25.9 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM33869.1 - 2.3e-05 25.0 0.0 8.8e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM33869.1 - 0.00012 22.7 0.0 0.00024 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM33869.1 - 0.00048 19.9 0.0 0.00085 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 GAM33869.1 - 0.007 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) p450 PF00067.22 GAM33870.1 - 6.2e-74 249.4 0.0 7.5e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 GAM33871.1 - 6.4e-20 71.3 0.0 1.1e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 GAM33871.1 - 0.00094 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain aGPT-Pplase2 PF18724.1 GAM33871.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 HTH_11 PF08279.12 GAM33871.1 - 0.056 13.4 0.0 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 HTH domain Methyltransf_33 PF10017.9 GAM33871.1 - 0.11 11.6 0.0 2.7 7.1 0.0 2.6 2 1 1 3 3 3 0 Histidine-specific methyltransferase, SAM-dependent TrmB PF01978.19 GAM33871.1 - 0.11 12.3 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Phosphodiest PF01663.22 GAM33872.1 - 6.7e-85 285.8 0.1 8.9e-85 285.4 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAM33872.1 - 5.4e-05 22.7 0.0 0.3 10.4 0.0 2.2 1 1 1 2 2 2 2 Sulfatase PNP_UDP_1 PF01048.20 GAM33873.1 - 4.2e-05 22.9 0.0 4.8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Serglycin PF04360.12 GAM33874.1 - 7 6.6 26.1 1.6e+02 2.1 25.2 2.3 1 1 0 1 1 1 0 Serglycin Mur_ligase_M PF08245.12 GAM33878.1 - 8.1e-07 29.2 0.0 1.9e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 GAM33878.1 - 0.00039 20.6 0.0 0.00075 19.7 0.0 1.4 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain TPR_12 PF13424.6 GAM33879.1 - 1.2e-11 44.8 2.7 0.0017 18.6 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAM33879.1 - 1.4e-08 35.1 0.1 0.026 15.0 0.0 4.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAM33879.1 - 1e-06 28.4 0.7 0.78 9.7 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM33879.1 - 3.1e-06 26.8 2.3 2.6 8.3 0.1 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM33879.1 - 2.3e-05 24.1 0.3 1.1 9.5 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM33879.1 - 0.00039 19.9 0.5 0.00067 19.1 0.5 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_1 PF00515.28 GAM33879.1 - 0.00087 19.0 0.0 1.9 8.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.6 GAM33879.1 - 0.00089 19.5 0.0 0.0028 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_14 PF13428.6 GAM33879.1 - 0.002 18.8 5.7 2.4 9.2 0.0 4.8 6 0 0 6 6 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAM33879.1 - 0.0087 16.6 0.2 1 10.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ATPase PF06745.13 GAM33879.1 - 0.0097 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 KaiC TPR_16 PF13432.6 GAM33879.1 - 0.01 16.4 0.0 0.16 12.6 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM33879.1 - 0.026 14.7 0.6 1.8 8.9 0.1 3.8 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 GAM33879.1 - 0.03 14.6 0.3 27 5.3 0.0 4.2 5 0 0 5 5 4 0 PPR repeat TPR_6 PF13174.6 GAM33879.1 - 0.058 14.0 2.1 9 7.2 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat HLH PF00010.26 GAM33880.1 - 2e-15 56.5 1.1 5.7e-15 55.0 0.9 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain KELK PF15796.5 GAM33880.1 - 0.04 14.4 1.5 0.087 13.3 1.5 1.5 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase YabA PF06156.13 GAM33880.1 - 0.1 13.2 4.0 0.18 12.5 3.4 1.6 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 GAM33880.1 - 0.11 13.0 5.0 0.25 11.8 5.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB HALZ PF02183.18 GAM33880.1 - 0.12 12.6 1.2 0.29 11.4 1.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper RNR_Alpha PF17975.1 GAM33880.1 - 0.13 12.7 0.9 0.29 11.7 0.9 1.5 1 0 0 1 1 1 0 Ribonucleotide reductase alpha domain Lzipper-MIP1 PF14389.6 GAM33880.1 - 0.37 11.1 3.3 0.52 10.6 0.7 2.5 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 APG6_N PF17675.1 GAM33880.1 - 0.5 10.9 5.5 0.84 10.2 5.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region LMBR1 PF04791.16 GAM33880.1 - 0.53 9.1 2.0 0.72 8.7 2.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2353 PF09789.9 GAM33880.1 - 0.62 9.4 7.0 0.77 9.1 6.3 1.4 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Rootletin PF15035.6 GAM33880.1 - 0.9 9.5 13.1 2.6 8.1 1.6 2.4 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.12 GAM33880.1 - 1 10.0 4.8 0.69 10.6 2.6 1.9 2 0 0 2 2 2 0 SlyX DUF1640 PF07798.11 GAM33880.1 - 3.2 7.8 6.6 3.6 7.6 4.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Hid1 PF12722.7 GAM33881.1 - 1.1 7.3 3.3 1.1 7.3 3.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mid2 PF04478.12 GAM33882.1 - 0.0018 18.1 0.0 0.0018 18.1 0.0 2.0 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor CcmH PF03918.14 GAM33882.1 - 0.13 11.5 1.1 1.8 7.9 0.2 2.6 3 0 0 3 3 3 0 Cytochrome C biogenesis protein CAP_N PF01213.19 GAM33882.1 - 0.25 10.8 4.8 0.39 10.2 4.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ribosomal_S27e PF01667.17 GAM33882.1 - 0.69 9.7 0.0 0.69 9.7 0.0 2.4 3 0 0 3 3 3 0 Ribosomal protein S27 Ofd1_CTDD PF10637.9 GAM33883.1 - 2e-97 325.6 0.1 1.1e-92 310.0 0.1 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 GAM33883.1 - 4.2e-26 91.4 0.0 1.2e-25 90.0 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 GAM33883.1 - 5.2e-14 52.9 0.0 1.2e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1963 PF09234.10 GAM33883.1 - 0.028 14.9 0.2 0.065 13.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) Aminotran_1_2 PF00155.21 GAM33884.1 - 2.8e-55 188.0 0.0 3.8e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Sod_Fe_N PF00081.22 GAM33884.1 - 6.2e-32 109.9 1.7 1.4e-31 108.8 1.7 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 GAM33884.1 - 2.5e-22 79.0 0.0 7.7e-22 77.4 0.0 1.8 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Beta_elim_lyase PF01212.21 GAM33884.1 - 0.05 12.9 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase APH PF01636.23 GAM33885.1 - 5.9e-06 26.4 0.0 1.3e-05 25.2 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 GAM33885.1 - 0.18 10.6 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) NOA36 PF06524.12 GAM33886.1 - 0.23 10.7 1.0 0.35 10.2 1.0 1.2 1 0 0 1 1 1 0 NOA36 protein Endosulfine PF04667.17 GAM33886.1 - 1.4 9.2 0.1 1.4 9.2 0.1 3.1 4 0 0 4 4 4 0 cAMP-regulated phosphoprotein/endosulfine conserved region ECH_1 PF00378.20 GAM33887.1 - 2.5e-17 63.0 0.0 2.7e-10 40.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM33887.1 - 0.00068 19.2 0.0 0.0009 18.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 GAM33887.1 - 0.014 15.4 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 SIT PF15330.6 GAM33888.1 - 0.72 10.3 2.3 5.7 7.4 0.7 2.3 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT TAFII55_N PF04658.13 GAM33889.1 - 2e-53 180.4 0.2 4.2e-53 179.3 0.2 1.6 1 0 0 1 1 1 1 TAFII55 protein conserved region Bromo_TP PF07524.13 GAM33890.1 - 7.4e-09 35.5 0.0 1.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 GAM33890.1 - 0.00074 19.6 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit BRO1 PF03097.18 GAM33891.1 - 1.9e-05 23.7 0.0 2.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain FliH PF02108.16 GAM33891.1 - 0.097 12.7 0.2 8.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Flagellar assembly protein FliH UPF0767 PF15990.5 GAM33891.1 - 0.15 12.3 0.0 5.7 7.2 0.0 2.7 2 0 0 2 2 2 0 UPF0767 family NDUFB10 PF10249.9 GAM33892.1 - 0.0024 18.4 0.0 0.0027 18.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Ank_2 PF12796.7 GAM33893.1 - 3.6e-24 85.1 0.3 2e-05 25.1 0.0 5.6 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM33893.1 - 6.6e-18 62.9 3.8 0.14 12.8 0.0 9.0 9 0 0 9 9 9 3 Ankyrin repeat Ank_4 PF13637.6 GAM33893.1 - 1.6e-16 60.5 8.6 0.0075 16.8 0.0 8.0 6 1 3 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 GAM33893.1 - 2.2e-11 43.7 7.3 1.6 9.3 0.1 8.2 8 1 1 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 GAM33893.1 - 1.3e-09 38.1 2.4 0.31 11.4 0.0 6.7 6 1 1 7 7 7 2 Ankyrin repeats (many copies) F-box-like PF12937.7 GAM33893.1 - 1.5e-06 27.9 0.1 3.4e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM33893.1 - 0.047 13.6 0.2 0.13 12.1 0.2 1.8 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 GAM33893.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 F-box Epimerase PF01370.21 GAM33894.1 - 9.2e-15 54.8 0.0 1.4e-14 54.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM33894.1 - 2.4e-10 39.9 0.0 4.6e-10 39.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM33894.1 - 1.9e-09 37.4 0.0 4.8e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GAM33894.1 - 2.4e-08 33.5 0.1 1.4e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 GAM33894.1 - 1e-07 32.0 0.1 1.6e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM33894.1 - 1.2e-06 28.3 0.1 2.3e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 GAM33894.1 - 0.00012 21.3 0.3 0.00025 20.3 0.3 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAM33894.1 - 0.0088 15.2 0.6 0.16 11.0 0.6 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NACHT PF05729.12 GAM33896.1 - 3e-11 43.5 0.1 7.3e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 GAM33896.1 - 3e-06 26.7 2.7 0.0025 17.1 0.0 3.1 2 1 1 3 3 3 2 KAP family P-loop domain AAA_16 PF13191.6 GAM33896.1 - 8e-06 26.3 4.4 1.4e-05 25.5 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAM33896.1 - 0.00037 20.8 0.1 0.0012 19.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAM33896.1 - 0.0037 16.5 0.1 0.014 14.5 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 GAM33896.1 - 0.031 14.7 0.0 0.21 12.0 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAM33896.1 - 0.032 14.2 0.1 0.22 11.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GAM33896.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region KinB_sensor PF16767.5 GAM33896.1 - 4.4 7.8 8.4 0.45 11.0 0.1 3.4 3 0 0 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB ArabFuran-catal PF09206.11 GAM33897.1 - 1.3e-154 514.2 12.8 1.7e-154 513.8 12.8 1.1 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic CBM_1 PF00734.18 GAM33897.1 - 6.1e-12 45.3 11.0 6.1e-12 45.3 11.0 3.0 4 0 0 4 4 4 1 Fungal cellulose binding domain Sugar_tr PF00083.24 GAM33901.1 - 1.4e-87 294.4 17.3 1.6e-87 294.2 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM33901.1 - 7.5e-28 97.5 25.9 1.5e-21 76.7 18.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAM33901.1 - 0.0038 16.1 14.0 0.12 11.2 2.0 2.3 2 0 0 2 2 2 2 MFS_1 like family Stevor PF17410.2 GAM33901.1 - 7.1 6.1 4.5 7.5 6.0 3.4 1.5 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame adh_short PF00106.25 GAM33902.1 - 1.4e-23 83.4 0.0 1.8e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33902.1 - 2.6e-15 56.6 0.0 3.3e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM33902.1 - 6.4e-07 29.5 0.1 1e-06 28.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.8 GAM33903.1 - 5.5e-13 48.5 0.1 5.6e-11 41.9 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Spore_III_AB PF09548.10 GAM33903.1 - 0.11 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Endomucin PF07010.12 GAM33904.1 - 0.095 12.7 4.8 0.11 12.4 4.8 1.1 1 0 0 1 1 1 0 Endomucin Fungal_trans PF04082.18 GAM33905.1 - 1.6e-12 47.0 1.6 2.7e-12 46.3 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 GAM33906.1 - 8.4e-21 74.8 0.0 2.1e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAM33906.1 - 5.6e-14 51.8 0.0 9.5e-14 51.0 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase INCENP_ARK-bind PF03941.15 GAM33906.1 - 0.023 14.6 0.1 0.091 12.7 0.1 2.0 1 1 0 1 1 1 0 Inner centromere protein, ARK binding region Fungal_trans PF04082.18 GAM33907.1 - 4.3e-19 68.6 3.2 5.9e-19 68.1 3.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF790 PF05626.11 GAM33907.1 - 0.0071 15.1 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF790) Pec_lyase_C PF00544.19 GAM33908.1 - 1.1e-41 142.7 12.1 1.5e-41 142.3 12.1 1.2 1 0 0 1 1 1 1 Pectate lyase adh_short_C2 PF13561.6 GAM33909.1 - 1.4e-32 113.2 0.1 1.9e-32 112.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM33909.1 - 3.9e-23 81.9 0.0 5.5e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase p450 PF00067.22 GAM33909.1 - 1.3e-13 50.5 0.0 1.8e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 KR PF08659.10 GAM33909.1 - 0.018 14.9 0.3 0.028 14.3 0.3 1.2 1 0 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.8 GAM33909.1 - 0.028 14.2 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-C2H2 PF00096.26 GAM33911.1 - 0.00017 21.9 12.5 0.46 11.0 0.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM33911.1 - 0.025 15.4 10.6 0.38 11.7 1.4 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger Sybindin PF04099.12 GAM33912.1 - 1.7e-47 160.9 0.0 2.7e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 GAM33912.1 - 3.3e-08 33.7 0.0 6.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region VWA_2 PF13519.6 GAM33913.1 - 2e-20 73.4 0.0 7.3e-20 71.6 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 GAM33913.1 - 2.7e-07 30.6 0.0 4.1e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 GAM33913.1 - 2.3e-06 28.0 0.2 3.5e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 GAM33913.1 - 0.039 13.9 0.1 0.11 12.5 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.9 GAM33914.1 - 1.3e-17 63.1 4.8 2.3e-17 62.4 4.8 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Aldedh PF00171.22 GAM33915.1 - 5.7e-146 486.7 0.0 7e-146 486.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAM33915.1 - 1.4e-05 24.7 0.0 9.4e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) RhoGAP PF00620.27 GAM33916.1 - 1.8e-35 122.0 0.3 4.3e-35 120.8 0.3 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 GAM33916.1 - 1.9e-30 104.8 38.4 4.1e-12 46.2 5.3 4.9 5 0 0 5 5 5 4 LIM domain AF-4 PF05110.13 GAM33916.1 - 0.71 7.9 2.1 1.2 7.2 2.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein UQ_con PF00179.26 GAM33917.1 - 7.7e-12 45.0 0.0 2.7e-06 27.1 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.22 GAM33917.1 - 0.1 12.9 0.2 0.23 11.8 0.1 1.5 1 1 1 2 2 2 0 RWD domain PAF PF15715.5 GAM33918.1 - 0.13 12.8 0.8 0.2 12.3 0.8 1.3 1 0 0 1 1 1 0 PCNA-associated factor histone like domain tRNA-synt_1f PF01921.18 GAM33919.1 - 0.021 13.8 0.0 0.09 11.7 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (K) 3Beta_HSD PF01073.19 GAM33920.1 - 2.4e-49 167.8 0.0 3.3e-48 164.1 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM33920.1 - 9e-18 64.6 0.1 1.6e-16 60.6 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAM33920.1 - 3.4e-11 42.8 0.0 3.4e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 GAM33920.1 - 4.6e-10 39.4 0.1 9.6e-07 28.5 0.1 3.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAM33920.1 - 8.2e-05 21.8 0.0 0.00045 19.4 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAM33920.1 - 0.011 14.9 0.0 0.17 11.0 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Pkinase PF00069.25 GAM33921.1 - 2.3e-59 200.9 0.0 8.3e-39 133.5 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM33921.1 - 1.1e-28 100.2 0.0 2.2e-20 73.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 GAM33921.1 - 1.1e-12 48.1 0.0 2.1e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 GAM33921.1 - 3.3e-08 33.2 0.0 3e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 GAM33921.1 - 6.3e-05 23.0 0.1 0.007 16.3 0.7 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAM33921.1 - 0.00096 18.6 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAM33921.1 - 0.0095 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain PAS_9 PF13426.7 GAM33921.1 - 0.024 14.9 0.0 0.062 13.6 0.0 1.7 1 0 0 1 1 1 0 PAS domain RIO1 PF01163.22 GAM33921.1 - 0.044 13.4 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 GAM33921.1 - 0.09 11.8 0.2 0.19 10.8 0.2 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 GAM33921.1 - 0.23 11.0 0.2 13 5.3 0.0 2.5 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 GAM33921.1 - 4.1 6.1 5.8 1.3 7.7 0.1 2.5 2 0 0 2 2 2 0 Fungal protein kinase SLAC1 PF03595.17 GAM33922.1 - 9.3e-93 311.0 51.2 1.2e-92 310.7 51.2 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel REV1_C PF16727.5 GAM33922.1 - 0.052 14.0 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain HTH_psq PF05225.16 GAM33923.1 - 0.00051 19.7 0.0 0.00099 18.8 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.6 GAM33923.1 - 0.0015 18.2 2.4 0.0031 17.3 0.0 2.5 3 0 0 3 3 3 1 Homeodomain-like domain MarR PF01047.22 GAM33923.1 - 0.0024 17.8 0.0 0.0063 16.4 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_38 PF13936.6 GAM33923.1 - 0.0051 16.5 1.7 0.031 14.0 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.6 GAM33923.1 - 0.0094 15.5 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 GAM33923.1 - 0.013 15.6 0.0 0.038 14.1 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_Tc5 PF03221.16 GAM33923.1 - 0.016 15.2 0.1 0.04 14.0 0.1 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain HTH_3 PF01381.22 GAM33923.1 - 0.032 14.3 0.7 0.14 12.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_Tnp_4 PF13613.6 GAM33923.1 - 0.041 13.6 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 GAM33923.1 - 0.063 13.6 4.6 2.2 8.7 0.1 2.6 2 1 0 2 2 2 0 Transposase HTH_7 PF02796.15 GAM33923.1 - 0.066 13.3 0.1 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase MarR_2 PF12802.7 GAM33923.1 - 0.072 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 MarR family Chibby PF14645.6 GAM33923.1 - 0.14 12.5 3.6 0.2 12.0 3.5 1.6 1 1 0 1 1 1 0 Chibby family DivIC PF04977.15 GAM33923.1 - 0.15 11.8 6.8 0.41 10.5 6.8 1.7 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 GAM33923.1 - 1.3 9.1 11.2 3.2 7.9 11.2 1.7 1 0 0 1 1 1 0 Basic region leucine zipper Fungal_trans PF04082.18 GAM33924.1 - 1.2e-05 24.4 0.0 3.1e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Arrestin_C PF02752.22 GAM33925.1 - 0.0091 16.5 0.0 0.048 14.1 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAM33925.1 - 0.025 14.6 0.0 0.42 10.7 0.0 2.6 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Fim-adh_lectin PF09222.10 GAM33925.1 - 0.078 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain RPEL PF02755.15 GAM33926.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 RPEL repeat HET PF06985.11 GAM33927.1 - 2.6e-07 31.1 0.0 0.00019 21.8 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MS_channel PF00924.18 GAM33928.1 - 1.5e-24 86.7 0.7 3.1e-24 85.7 0.7 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 GAM33928.1 - 0.00027 20.3 0.0 0.00066 19.1 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 GAM33928.1 - 0.00092 18.6 0.3 0.0023 17.4 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAM33928.1 - 0.0012 18.6 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 GAM33928.1 - 0.021 15.3 0.2 0.064 13.7 0.2 1.8 1 0 0 1 1 1 0 EF-hand domain pair Senescence PF06911.12 GAM33928.1 - 0.022 15.1 0.1 0.039 14.3 0.1 1.3 1 0 0 1 1 1 0 Senescence-associated protein Amidohydro_2 PF04909.14 GAM33929.1 - 2.6e-16 60.3 0.0 2.8e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase DUF4461 PF14688.6 GAM33930.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) FAA_hydrolase PF01557.18 GAM33931.1 - 2.2e-61 207.3 0.0 2.9e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase PF00903.25 GAM33932.1 - 2.5e-09 37.4 5.4 2.2e-08 34.3 2.8 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.19 GAM33933.1 - 4.1e-34 118.4 0.0 4.3e-33 115.0 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAM33933.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family MatE PF01554.18 GAM33934.1 - 0.0017 18.0 2.6 0.0017 18.0 2.6 3.1 4 0 0 4 4 4 2 MatE Chromate_transp PF02417.15 GAM33935.1 - 3.9e-58 196.0 32.3 7.8e-31 107.3 14.4 2.4 2 0 0 2 2 2 2 Chromate transporter DUF682 PF05081.12 GAM33936.1 - 0.016 14.9 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF682) Tubulin PF00091.25 GAM33937.1 - 6.6e-65 219.0 0.0 9e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAM33937.1 - 2.6e-45 153.7 0.0 4e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAM33937.1 - 0.0023 17.7 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Mito_carr PF00153.27 GAM33938.1 - 1.9e-65 216.8 1.4 3.2e-21 75.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 GAM33938.1 - 0.065 13.5 0.0 4.5 7.6 0.0 2.6 2 1 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DNA_methylase PF00145.17 GAM33939.1 - 4.7e-07 29.5 0.0 8.7e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DUF5419 PF17441.2 GAM33939.1 - 0.1 12.7 0.2 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5419) Transglut_core2 PF13369.6 GAM33939.1 - 0.17 11.5 0.0 0.61 9.6 0.0 1.9 2 0 0 2 2 2 0 Transglutaminase-like superfamily TauD PF02668.16 GAM33941.1 - 1.9e-44 152.5 0.3 2.7e-44 152.0 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 GAM33941.1 - 4.3e-06 27.3 0.3 1.3e-05 25.7 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 GAM33941.1 - 0.0011 18.1 0.0 0.0047 16.1 0.0 1.9 1 1 0 1 1 1 1 CsiD Glutaredoxin PF00462.24 GAM33942.1 - 4e-18 65.4 0.0 1e-16 60.9 0.0 2.5 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 GAM33942.1 - 3.8e-11 42.9 0.0 9.6e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAM33942.1 - 0.03 14.6 0.0 9.2 6.7 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like RNase_T PF00929.24 GAM33943.1 - 3.3e-11 44.0 0.0 1.2e-10 42.2 0.0 1.9 1 1 0 1 1 1 1 Exonuclease Cnn_1N PF07989.11 GAM33944.1 - 0.0072 16.5 0.4 2.7 8.2 0.0 2.8 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 TSC22 PF01166.18 GAM33944.1 - 0.021 15.1 1.5 4.5 7.6 0.3 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family FapA PF03961.13 GAM33944.1 - 0.029 13.0 0.2 0.05 12.2 0.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cep57_MT_bd PF06657.13 GAM33944.1 - 0.042 14.3 1.5 0.22 12.0 1.5 2.3 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 CCDC92 PF14916.6 GAM33944.1 - 0.063 13.1 3.4 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Yippee-Mis18 PF03226.14 GAM33944.1 - 0.22 11.8 1.6 0.46 10.7 1.6 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2757 PF10955.8 GAM33944.1 - 0.25 11.6 0.0 0.25 11.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) DUF2703 PF10865.8 GAM33944.1 - 0.41 10.8 2.9 20 5.4 0.2 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF2703) FlaC_arch PF05377.11 GAM33944.1 - 1.3 9.5 3.6 15 6.1 0.0 3.2 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Beta_elim_lyase PF01212.21 GAM33945.1 - 1.8e-70 237.6 0.0 2.1e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GAM33945.1 - 0.046 12.9 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAM33945.1 - 0.085 11.4 0.1 0.21 10.1 0.1 1.7 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.25 GAM33946.1 - 5e-72 242.4 0.0 7.1e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM33946.1 - 4.4e-36 124.5 0.0 6.5e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 GAM33946.1 - 2.2e-10 40.7 0.2 4.6e-09 36.5 0.1 2.5 2 0 0 2 2 2 1 FHA domain APH PF01636.23 GAM33946.1 - 4.3e-05 23.5 0.5 0.85 9.5 0.0 3.9 3 2 1 4 4 4 2 Phosphotransferase enzyme family Yop-YscD_cpl PF16697.5 GAM33946.1 - 0.00034 20.9 0.0 0.0011 19.2 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 GAM33946.1 - 0.00061 19.2 0.0 0.00093 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM33946.1 - 0.0037 16.7 0.4 0.0063 15.9 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM33946.1 - 0.072 12.7 0.3 0.12 12.0 0.3 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 GAM33946.1 - 0.084 11.6 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 GAM33946.1 - 0.18 11.4 0.1 0.38 10.3 0.1 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 MFS_1 PF07690.16 GAM33947.1 - 1.7e-45 155.5 39.6 1.7e-45 155.5 39.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM33947.1 - 3.1e-10 39.5 9.9 3.1e-10 39.5 9.9 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 GAM33947.1 - 0.00042 19.3 11.3 0.00084 18.3 1.8 3.1 1 1 1 2 2 2 2 MFS_1 like family MFS_4 PF06779.14 GAM33947.1 - 0.00089 18.7 10.0 0.00089 18.7 10.0 2.6 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB RNA_replicase_B PF03431.13 GAM33947.1 - 0.0029 16.2 0.0 0.0041 15.6 0.0 1.1 1 0 0 1 1 1 1 RNA replicase, beta-chain Mobilization_B PF17511.2 GAM33947.1 - 2.8 8.3 5.7 0.92 9.9 0.2 2.4 2 0 0 2 2 2 0 Mobilization protein B FSH1 PF03959.13 GAM33948.1 - 2.4e-31 109.1 0.0 3.4e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 GAM33948.1 - 0.001 18.9 0.0 0.096 12.5 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 GAM33948.1 - 0.015 15.9 0.0 0.019 15.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family ketoacyl-synt PF00109.26 GAM33949.1 - 2.5e-72 243.5 1.5 2.1e-71 240.5 0.1 3.0 4 0 0 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain HTH_51 PF18558.1 GAM33949.1 - 3e-37 126.4 0.0 9.1e-37 124.8 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain Ketoacyl-synt_C PF02801.22 GAM33949.1 - 5.7e-30 103.8 0.0 1.6e-29 102.3 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 GAM33949.1 - 1.4e-25 90.5 0.0 3.2e-23 82.8 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.12 GAM33949.1 - 9e-25 87.3 0.0 1.9e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein SAT PF16073.5 GAM33949.1 - 1.6e-12 47.7 8.1 1.2e-09 38.3 0.2 4.1 4 1 0 4 4 4 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_12 PF08242.12 GAM33949.1 - 3e-12 47.1 0.0 9.1e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 GAM33949.1 - 4.6e-11 42.9 0.5 1.4e-10 41.4 0.2 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 GAM33949.1 - 6.3e-08 33.2 0.0 2e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 GAM33949.1 - 6.3e-08 32.4 0.0 1.4e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PS-DH PF14765.6 GAM33949.1 - 2.1e-07 30.5 0.0 4.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 GAM33949.1 - 2.1e-07 31.4 0.0 5.6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 GAM33949.1 - 1.3e-06 28.0 1.4 4.4e-06 26.2 0.1 2.5 4 0 0 4 4 4 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.6 GAM33949.1 - 8.7e-06 25.7 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM33949.1 - 1.2e-05 25.8 0.0 3.6e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KR PF08659.10 GAM33949.1 - 0.0024 17.8 0.1 0.0094 15.9 0.0 2.0 2 0 0 2 2 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM33949.1 - 0.0035 16.5 0.0 0.024 13.8 0.0 2.4 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein Methyltransf_31 PF13847.6 GAM33949.1 - 0.0046 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DXP_reductoisom PF02670.16 GAM33949.1 - 0.14 12.9 0.0 0.53 11.0 0.0 2.0 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Transferase PF02458.15 GAM33950.1 - 2.1e-17 62.9 0.0 3.4e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Transferase family PapA_C PF16911.5 GAM33951.1 - 6.9e-05 22.9 0.0 0.61 10.2 0.0 2.6 2 0 0 2 2 2 2 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus ADH_zinc_N PF00107.26 GAM33952.1 - 1.7e-08 34.5 0.1 4.1e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM33952.1 - 9e-07 28.7 0.1 6.3e-06 26.0 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAM33952.1 - 0.0025 17.7 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Tri3 PF07428.11 GAM33953.1 - 1.8e-06 27.1 0.1 1.6e-05 24.1 0.0 2.0 1 1 1 2 2 2 2 15-O-acetyltransferase Tri3 ketoacyl-synt PF00109.26 GAM33954.1 - 4.9e-73 245.8 0.1 9.9e-73 244.8 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAM33954.1 - 7.7e-33 113.0 0.0 2e-32 111.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 GAM33954.1 - 2.4e-22 79.9 0.0 1.6e-20 73.9 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain SAT PF16073.5 GAM33954.1 - 1.7e-14 54.1 4.9 2.6e-13 50.3 0.2 3.8 3 1 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 GAM33954.1 - 1.2e-12 48.0 1.8 3.9e-07 30.3 0.6 2.9 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.6 GAM33954.1 - 1.4e-12 47.4 0.0 2.9e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 GAM33954.1 - 2.9e-10 40.6 0.0 7.8e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 GAM33954.1 - 4.7e-05 22.9 0.1 9.1e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.21 GAM33955.1 - 8.6e-22 77.8 0.0 1.2e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM33955.1 - 2.5e-11 43.1 0.0 3.4e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAM33955.1 - 4.1e-11 42.5 0.0 6.9e-10 38.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 GAM33955.1 - 1.2e-10 41.3 0.0 1.9e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAM33955.1 - 1.6e-06 28.2 0.0 7.3e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAM33955.1 - 3.6e-05 23.1 0.0 5.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 GAM33955.1 - 0.00014 21.4 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM33955.1 - 0.00022 21.2 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 GAM33955.1 - 0.003 17.2 0.0 0.028 14.0 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.6 GAM33955.1 - 0.021 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Abhydrolase_6 PF12697.7 GAM33956.1 - 5.1e-14 53.4 1.1 7.1e-14 52.9 1.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM33956.1 - 8.1e-08 31.8 0.0 1.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM33956.1 - 0.024 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold HEAT_UF PF18817.1 GAM33956.1 - 0.04 14.2 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Repeat of uncharacterized protein PH0542 Ser_hydrolase PF06821.13 GAM33956.1 - 0.067 13.1 0.5 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase DUF1350 PF07082.11 GAM33956.1 - 0.08 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) ADH_zinc_N PF00107.26 GAM33957.1 - 1.6e-11 44.3 0.0 2.7e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM33957.1 - 9.7e-09 35.1 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM33957.1 - 0.071 14.2 0.0 0.13 13.3 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.25 GAM33958.1 - 2.2e-10 40.3 0.0 3.5e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM33958.1 - 1.2e-07 31.8 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 GAM33958.1 - 8.2e-07 28.8 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.16 GAM33959.1 - 1.2e-27 96.8 31.4 1.7e-27 96.3 31.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Esterase PF00756.20 GAM33959.1 - 1.1e-06 28.5 0.0 2.4e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 GAM33959.1 - 0.0035 16.9 0.0 0.01 15.3 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAM33959.1 - 0.015 15.9 0.1 0.045 14.4 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM33959.1 - 0.019 14.2 0.3 1.8 7.7 0.0 2.5 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 GAM33959.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_1 PF00561.20 GAM33959.1 - 0.94 9.1 3.4 4.3 6.9 0.2 2.7 2 1 1 3 3 3 0 alpha/beta hydrolase fold SLATT_fungal PF18142.1 GAM33959.1 - 1.8 8.6 4.4 4.8 7.2 4.4 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Arteri_Gl PF00951.18 GAM33959.1 - 2.5 7.9 9.2 0.11 12.3 2.6 2.1 2 1 0 2 2 2 0 Arterivirus GL envelope glycoprotein Fungal_trans PF04082.18 GAM33960.1 - 8.2e-32 110.3 0.7 2.6e-31 108.7 0.5 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 GAM33960.1 - 1.1e-19 70.6 6.0 1.1e-19 70.6 6.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 GAM33960.1 - 0.048 11.9 2.4 1.1 7.5 0.6 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family GMC_oxred_N PF00732.19 GAM33961.1 - 5e-62 209.9 0.0 5.5e-60 203.2 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM33961.1 - 1.7e-36 125.9 0.0 3e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAM33961.1 - 0.001 18.2 0.2 0.0015 17.6 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 GAM33961.1 - 0.0042 16.4 0.4 0.0085 15.4 0.1 1.6 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 GAM33961.1 - 0.0061 16.2 0.1 0.1 12.2 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM33961.1 - 0.012 15.8 0.0 0.042 14.1 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM33961.1 - 0.043 12.9 0.1 3.8 6.5 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 GAM33961.1 - 0.067 12.4 0.0 0.68 9.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM33961.1 - 0.093 11.6 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase peroxidase PF00141.23 GAM33963.1 - 2.7e-85 285.7 0.0 3.4e-45 154.5 0.0 2.2 2 0 0 2 2 2 2 Peroxidase GST_C_3 PF14497.6 GAM33963.1 - 0.15 12.3 0.0 24 5.2 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Tri3 PF07428.11 GAM33964.1 - 0.0005 19.1 0.0 0.002 17.1 0.0 1.7 1 1 1 2 2 2 1 15-O-acetyltransferase Tri3 p450 PF00067.22 GAM33965.1 - 4.3e-80 269.7 0.0 5.2e-80 269.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 GAM33966.1 - 2.5e-25 89.2 56.0 5e-25 88.2 54.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM33966.1 - 1.6e-13 50.0 13.1 3.1e-13 49.0 13.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aldo_ket_red PF00248.21 GAM33967.1 - 2.7e-38 131.8 0.0 3.1e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FSH1 PF03959.13 GAM33968.1 - 2.9e-30 105.5 0.0 3.7e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 GAM33968.1 - 0.038 13.8 0.0 0.78 9.5 0.0 2.2 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Fas_alpha_ACP PF18325.1 GAM33970.1 - 4.4e-54 183.2 0.0 1.2e-53 181.8 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 GAM33970.1 - 4.5e-34 117.9 0.1 8.8e-34 116.9 0.1 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 GAM33970.1 - 2.1e-21 76.7 0.0 4.5e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAM33970.1 - 2.5e-19 69.4 0.2 1.1e-18 67.4 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 GAM33970.1 - 0.01 15.3 0.0 0.027 13.9 0.0 1.8 1 0 0 1 1 1 0 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33970.1 - 0.056 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM33970.1 - 0.15 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 KR domain DUF1729 PF08354.10 GAM33971.1 - 7.9e-150 498.6 0.0 1.3e-149 498.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 GAM33971.1 - 2.8e-47 161.8 0.0 6.4e-47 160.6 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain FAS_meander PF17951.1 GAM33971.1 - 1e-25 90.2 0.0 2.1e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 GAM33971.1 - 6.5e-23 80.6 0.1 1.3e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 GAM33971.1 - 1.7e-22 80.4 0.0 6.6e-22 78.4 0.0 2.1 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 GAM33971.1 - 3.5e-08 33.6 0.0 8.5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 GAM33971.1 - 0.0028 17.1 0.1 0.02 14.3 0.1 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase Fungal_trans PF04082.18 GAM33972.1 - 1.2e-11 44.1 1.2 1.1e-10 41.0 0.0 2.4 1 1 1 3 3 3 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.26 GAM33973.1 - 1.9e-73 247.2 0.0 6.1e-73 245.5 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain HTH_51 PF18558.1 GAM33973.1 - 1.7e-33 114.4 0.0 5.3e-33 112.8 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain Ketoacyl-synt_C PF02801.22 GAM33973.1 - 1.1e-31 109.3 0.1 1.8e-30 105.4 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 GAM33973.1 - 9.7e-25 87.7 0.6 2.5e-23 83.1 0.3 2.2 2 0 0 2 2 2 1 Acyl transferase domain PP-binding PF00550.25 GAM33973.1 - 5.8e-23 81.0 5.0 1.5e-11 44.5 0.1 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site SAT PF16073.5 GAM33973.1 - 1e-15 58.2 4.7 1.8e-13 50.8 0.0 4.2 3 1 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_12 PF08242.12 GAM33973.1 - 2.6e-14 53.7 0.0 6.5e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PS-DH PF14765.6 GAM33973.1 - 1.4e-11 44.2 0.0 2.5e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.12 GAM33973.1 - 2.2e-10 40.1 0.0 0.00052 19.3 0.0 2.6 1 1 1 2 2 2 2 Male sterility protein Methyltransf_25 PF13649.6 GAM33973.1 - 6.7e-08 33.1 0.0 1.8e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM33973.1 - 1.4e-07 31.5 0.0 8.5e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 GAM33973.1 - 2.5e-07 30.3 0.1 1.9e-06 27.4 0.1 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.12 GAM33973.1 - 2.8e-07 31.1 0.0 8e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM33973.1 - 1.4e-05 25.0 0.0 3.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAM33973.1 - 0.00041 20.8 0.2 0.001 19.5 0.2 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 GAM33973.1 - 0.00075 19.0 0.0 0.004 16.6 0.0 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM33973.1 - 0.0099 15.0 0.0 0.074 12.2 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 GAM33974.1 - 2.5e-41 141.3 0.0 3.2e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM33974.1 - 6.2e-37 127.4 0.0 8.7e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM33974.1 - 4.6e-11 42.9 0.0 6.5e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAM33974.1 - 0.0049 16.3 0.0 0.007 15.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.19 GAM33974.1 - 0.034 13.1 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM33974.1 - 0.081 12.4 0.0 1.2 8.5 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Transferase PF02458.15 GAM33975.1 - 1e-25 90.3 0.0 1.3e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Transferase family DUF711 PF05167.12 GAM33975.1 - 0.027 13.4 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) FAD_binding_3 PF01494.19 GAM33976.1 - 6.7e-21 74.9 0.0 4.2e-10 39.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAM33976.1 - 3.1e-05 24.1 0.0 0.00013 22.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM33976.1 - 0.00013 21.7 1.1 0.00095 18.8 0.6 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM33976.1 - 0.0012 18.9 0.0 0.003 17.6 0.0 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAM33976.1 - 0.0014 19.2 0.0 0.006 17.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM33976.1 - 0.0042 16.4 0.1 0.033 13.4 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM33976.1 - 0.015 14.2 2.8 0.27 10.0 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_2 PF00890.24 GAM33976.1 - 0.019 14.1 0.1 0.028 13.5 0.1 1.5 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 GAM33976.1 - 0.03 13.6 0.2 0.14 11.4 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.23 GAM33977.1 - 9.4e-26 90.2 6.3 1.6e-25 89.5 6.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM33977.1 - 2.3e-10 40.4 0.0 4.4e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like BBE PF08031.12 GAM33978.1 - 0.11 12.6 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Berberine and berberine like Acetyltransf_1 PF00583.25 GAM33979.1 - 7.3e-13 48.8 0.0 9e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM33979.1 - 1.2e-10 41.4 0.0 1.6e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM33979.1 - 7.7e-09 35.9 0.0 1.1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM33979.1 - 8.7e-06 25.6 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 GAM33979.1 - 0.0009 19.4 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM33979.1 - 0.0016 18.5 0.0 0.0086 16.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FA_desaturase_2 PF03405.14 GAM33979.1 - 0.06 12.2 0.0 0.075 11.9 0.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF2156 PF09924.9 GAM33979.1 - 0.072 12.1 0.0 0.085 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) FeS PF04060.13 GAM33979.1 - 0.097 12.3 0.2 0.21 11.3 0.2 1.5 1 0 0 1 1 1 0 Putative Fe-S cluster Acetyltransf_CG PF14542.6 GAM33979.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ADH_zinc_N PF00107.26 GAM33980.1 - 1e-09 38.5 0.0 1.3e-09 38.1 0.0 1.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM33980.1 - 1.7e-06 27.9 1.0 5.8e-06 26.1 0.6 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM33980.1 - 0.014 16.5 0.0 0.023 15.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAM33980.1 - 0.022 14.2 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus F-box-like PF12937.7 GAM33981.1 - 7.3e-05 22.6 6.2 0.0024 17.7 4.1 3.3 2 1 0 2 2 2 1 F-box-like LRRFIP PF09738.9 GAM33982.1 - 0.018 14.5 3.9 0.022 14.3 3.9 1.1 1 0 0 1 1 1 0 LRRFIP family Phytochelatin_C PF09328.10 GAM33982.1 - 0.021 14.1 0.1 0.026 13.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) Asp_Glu_race PF01177.22 GAM33983.1 - 6.2e-30 104.7 0.0 7.2e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Alginate_lyase2 PF08787.11 GAM33984.1 - 7.7e-20 71.7 0.4 8.5e-20 71.6 0.4 1.0 1 0 0 1 1 1 1 Alginate lyase MFS_1 PF07690.16 GAM33985.1 - 9.8e-18 64.2 17.7 1.3e-17 63.8 17.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.11 GAM33985.1 - 0.054 13.8 2.6 1.4 9.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) DUF1934 PF09148.10 GAM33986.1 - 0.046 13.7 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1934) Sulfatase PF00884.23 GAM33987.1 - 1.1e-45 156.4 0.1 6.9e-44 150.5 0.0 2.5 2 1 0 2 2 2 1 Sulfatase DUF4976 PF16347.5 GAM33987.1 - 2.9e-07 30.7 0.3 7.6e-07 29.3 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 GAM33987.1 - 2.6e-06 27.3 0.1 1.3e-05 25.0 0.0 2.1 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 GAM33987.1 - 0.069 13.9 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 GAM33987.1 - 0.096 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF229 PF02995.17 GAM33987.1 - 0.27 9.8 0.0 0.36 9.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) p450 PF00067.22 GAM33988.1 - 4.4e-67 226.8 0.0 5.6e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Neurensin PF14927.6 GAM33988.1 - 0.081 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Neurensin Isochorismatase PF00857.20 GAM33989.1 - 1.2e-22 80.9 0.1 4.2e-22 79.2 0.1 1.9 2 0 0 2 2 2 1 Isochorismatase family Fungal_trans PF04082.18 GAM33989.1 - 0.00053 19.1 0.0 0.00087 18.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HgmA PF04209.13 GAM33990.1 - 1.5e-136 455.5 0.1 6.9e-136 453.3 0.1 1.8 1 1 0 1 1 1 1 homogentisate 1,2-dioxygenase Transp_cyt_pur PF02133.15 GAM33991.1 - 6.3e-26 91.1 23.4 2.8e-25 89.0 23.4 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ank_2 PF12796.7 GAM33992.1 - 4.3e-25 88.1 0.4 4.7e-13 49.5 0.0 4.1 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM33992.1 - 1.7e-23 82.7 0.4 2.6e-10 40.6 0.1 4.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM33992.1 - 2.2e-21 75.6 1.6 3.1e-12 46.5 0.3 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM33992.1 - 2.1e-20 70.6 1.8 8.4e-06 25.8 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 GAM33992.1 - 3.3e-20 71.6 5.3 3.6e-08 33.5 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Epimerase PF01370.21 GAM33993.1 - 6.9e-16 58.4 0.0 9.6e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM33993.1 - 1.2e-10 40.9 0.0 1.4e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAM33993.1 - 1.2e-09 38.4 0.1 2.1e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM33993.1 - 2.2e-09 37.2 0.1 4.8e-09 36.1 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 GAM33993.1 - 3.3e-06 26.7 0.0 4.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GAM33993.1 - 0.0026 17.0 0.1 0.03 13.5 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 GAM33993.1 - 0.0054 15.9 0.2 0.037 13.1 0.2 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAM33993.1 - 0.042 13.0 0.0 0.085 12.0 0.1 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Cellulase PF00150.18 GAM33994.1 - 8.4e-43 146.8 5.9 4.3e-22 78.8 1.9 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 GAM33994.1 - 2.4e-12 46.6 16.4 2.4e-12 46.6 16.4 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 GAM33994.1 - 0.054 13.8 0.4 0.11 12.8 0.4 1.5 1 0 0 1 1 1 0 Toxin 7 MFS_1 PF07690.16 GAM33995.1 - 1.5e-32 112.9 25.7 1.5e-32 112.9 25.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_23 PF13489.6 GAM33996.1 - 3.3e-21 75.8 0.0 5e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM33996.1 - 2.3e-15 57.1 0.0 6.6e-15 55.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM33996.1 - 3.2e-14 53.4 0.0 6.6e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM33996.1 - 3e-12 46.6 0.0 1.1e-10 41.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM33996.1 - 3.1e-09 37.5 0.0 2e-08 34.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM33996.1 - 2.2e-07 30.4 0.0 3.6e-06 26.5 0.0 2.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 GAM33996.1 - 2.5e-05 23.7 0.0 0.0002 20.8 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 GAM33996.1 - 3.5e-05 23.4 0.0 0.0012 18.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 GAM33996.1 - 8.1e-05 22.8 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 GAM33996.1 - 0.00013 21.5 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 GAM33996.1 - 0.0014 18.2 0.0 0.028 13.9 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 GAM33996.1 - 0.0021 17.4 0.0 0.012 14.9 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 GAM33996.1 - 0.0062 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase UPF0146 PF03686.13 GAM33996.1 - 0.011 15.6 0.0 0.083 12.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Methyltransf_16 PF10294.9 GAM33996.1 - 0.045 13.5 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase GidB PF02527.15 GAM33996.1 - 0.19 11.1 0.0 0.45 9.8 0.0 1.7 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G p450 PF00067.22 GAM33997.1 - 8.5e-57 192.9 0.0 1.1e-56 192.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 dCMP_cyt_deam_1 PF00383.23 GAM33998.1 - 6.7e-09 35.6 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAM33998.1 - 4.2e-06 26.5 0.0 6.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Glyco_hydro_16 PF00722.21 GAM33999.1 - 1.3e-16 60.6 0.4 2.4e-16 59.7 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 GAM34000.1 - 1.2e-54 185.2 1.1 1.2e-54 185.2 1.1 2.5 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAM34000.1 - 0.0032 17.3 0.0 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glycophorin_A PF01102.18 GAM34000.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A WSC PF01822.19 GAM34001.1 - 6.9e-79 260.1 87.4 1.9e-19 69.6 16.4 5.9 6 0 0 6 6 6 5 WSC domain Glyoxal_oxid_N PF07250.11 GAM34001.1 - 1.1e-24 86.9 0.0 7.7e-24 84.2 0.0 2.2 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus peroxidase PF00141.23 GAM34001.1 - 4.7e-21 75.5 0.0 1e-20 74.4 0.0 1.5 1 0 0 1 1 1 1 Peroxidase DUF1929 PF09118.11 GAM34001.1 - 5.4e-19 68.3 0.0 2.2e-18 66.3 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) PSI_PSAK PF01241.18 GAM34001.1 - 0.072 13.1 0.5 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 Photosystem I psaG / psaK MFS_1 PF07690.16 GAM34002.1 - 2.4e-30 105.7 25.0 3.3e-30 105.2 25.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily GST_N_3 PF13417.6 GAM34002.1 - 3.4e-17 62.6 0.0 6.7e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM34002.1 - 3.6e-14 52.8 0.0 7e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Sugar_tr PF00083.24 GAM34002.1 - 1.8e-13 50.2 11.8 2.9e-13 49.5 11.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter GST_N PF02798.20 GAM34002.1 - 4.3e-13 49.4 0.0 8.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GAM34002.1 - 0.00042 20.5 0.0 0.00078 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 GAM34002.1 - 0.0094 16.0 0.1 0.03 14.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM34002.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain S1-P1_nuclease PF02265.16 GAM34002.1 - 0.22 11.3 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 S1/P1 Nuclease NMT1 PF09084.11 GAM34003.1 - 7.3e-11 42.4 0.0 1.6e-10 41.3 0.0 1.7 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 GAM34003.1 - 0.00055 19.4 0.0 0.0009 18.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 GAM34003.1 - 0.0025 17.6 0.0 0.0076 16.0 0.0 1.9 1 1 0 1 1 1 1 NMT1-like family NMO PF03060.15 GAM34004.1 - 2.7e-58 197.9 2.0 8.9e-57 192.9 2.0 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAM34004.1 - 6e-13 48.5 0.1 4.8e-12 45.5 0.1 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAM34004.1 - 4.1e-05 22.8 0.7 7.3e-05 22.0 0.7 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 GAM34004.1 - 0.0036 16.5 2.1 0.078 12.1 2.1 2.3 1 1 0 1 1 1 1 Conserved region in glutamate synthase DUF1729 PF08354.10 GAM34004.1 - 0.16 10.9 0.7 0.5 9.2 0.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1729) NB-ARC PF00931.22 GAM34005.1 - 2.7e-07 30.1 0.0 4.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 GAM34005.1 - 0.00095 19.4 0.4 0.0044 17.3 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM34005.1 - 0.0011 19.6 0.1 3.9 8.6 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat NACHT PF05729.12 GAM34005.1 - 0.0016 18.4 0.0 0.0041 17.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAM34005.1 - 0.004 17.6 0.3 0.024 15.0 0.3 2.6 1 1 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.14 GAM34005.1 - 0.0041 16.7 0.0 0.0079 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_10 PF13374.6 GAM34005.1 - 0.0088 15.9 0.1 0.037 13.9 0.1 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 GAM34005.1 - 0.0092 16.6 0.0 0.034 14.7 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family AAA_22 PF13401.6 GAM34005.1 - 0.065 13.5 0.0 0.24 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain Hydrolase_4 PF12146.8 GAM34005.1 - 0.099 11.9 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DDE_1 PF03184.19 GAM34006.1 - 3.1e-27 95.4 0.0 5.2e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 GAM34006.1 - 0.00042 20.3 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain YopX PF09643.10 GAM34006.1 - 0.17 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 YopX protein DUF676 PF05057.14 GAM34007.1 - 9e-05 22.1 0.2 0.00062 19.4 0.0 1.9 1 1 1 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 GAM34007.1 - 0.026 15.2 0.0 0.091 13.4 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM34007.1 - 0.032 13.5 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAM34007.1 - 0.099 12.3 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein TPR_12 PF13424.6 GAM34008.1 - 1.6e-167 544.2 63.4 1.4e-20 73.4 0.2 9.4 1 1 10 11 11 11 11 Tetratricopeptide repeat TPR_10 PF13374.6 GAM34008.1 - 1.8e-144 466.4 30.4 3.7e-13 48.9 0.0 11.5 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_1 PF00515.28 GAM34008.1 - 2.3e-52 172.8 20.6 0.00037 20.2 0.0 11.6 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.6 GAM34008.1 - 4.3e-42 139.1 22.3 0.0014 18.5 0.1 12.1 12 0 0 12 12 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 GAM34008.1 - 1.2e-37 124.9 14.7 0.0073 16.4 0.0 11.8 12 0 0 12 12 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 GAM34008.1 - 2.3e-27 92.8 24.2 0.044 13.9 2.9 11.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_14 PF13428.6 GAM34008.1 - 1.8e-24 84.3 18.1 0.58 11.1 0.0 12.5 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAM34008.1 - 7.5e-21 74.5 13.5 0.0079 16.8 0.0 10.9 6 3 4 10 10 9 7 Tetratricopeptide repeat TPR_17 PF13431.6 GAM34008.1 - 4.5e-20 70.5 0.3 1.8 9.1 0.0 11.3 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM34008.1 - 1.2e-17 64.3 25.7 3.6e-07 29.9 1.3 4.5 1 1 3 4 4 4 4 MalT-like TPR region TPR_4 PF07721.14 GAM34008.1 - 2.3e-17 61.8 0.0 1 10.2 0.0 10.1 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM34008.1 - 4.8e-15 55.8 10.7 0.04 14.4 0.0 7.1 5 1 2 7 7 7 5 Tetratricopeptide repeat PPR PF01535.20 GAM34008.1 - 5.4e-07 29.4 7.9 59 4.2 0.0 10.0 11 0 0 11 11 11 0 PPR repeat DUF1925 PF09094.11 GAM34008.1 - 3.6e-05 24.0 11.8 13 6.2 0.0 8.4 9 1 1 10 10 10 0 Domain of unknown function (DUF1925) NRBF2_MIT PF17169.4 GAM34008.1 - 0.00028 21.0 16.3 31 4.9 0.0 9.1 9 2 0 9 9 8 0 MIT domain of nuclear receptor-binding factor 2 LAMTOR5 PF16672.5 GAM34008.1 - 0.012 15.6 0.3 53 3.8 0.0 5.2 3 1 2 6 6 6 0 Ragulator complex protein LAMTOR5 AAA_16 PF13191.6 GAM34008.1 - 0.015 15.7 0.2 0.072 13.5 0.1 2.3 1 1 1 2 2 2 0 AAA ATPase domain nec1 PF10379.9 GAM34008.1 - 0.025 14.1 0.1 38 3.7 0.0 4.6 3 1 2 5 5 5 0 Virulence protein nec1 DUF2225 PF09986.9 GAM34008.1 - 0.032 14.0 0.7 1 9.0 0.0 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Chalcone_3 PF16036.5 GAM34008.1 - 0.06 13.5 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Chalcone isomerase-like TPR_11 PF13414.6 GAM34008.1 - 0.11 12.2 20.4 8.8 6.1 0.0 8.8 10 0 0 10 10 10 0 TPR repeat TPR_3 PF07720.12 GAM34008.1 - 0.58 10.2 11.7 12 6.0 0.4 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_21 PF09976.9 GAM34008.1 - 0.62 9.7 17.8 1 9.1 0.1 7.1 2 2 5 9 9 9 0 Tetratricopeptide repeat-like domain DUF3095 PF11294.8 GAM34008.1 - 1.1 8.3 4.0 19 4.2 0.1 3.4 2 2 2 5 5 5 0 Protein of unknown function (DUF3095) Gln_amidase PF15644.6 GAM34008.1 - 1.5 9.9 6.5 71 4.5 0.1 5.2 3 2 1 5 5 5 0 Papain fold toxin 1, glutamine deamidase DDE_1 PF03184.19 GAM34009.1 - 5.9e-29 100.9 0.0 1e-28 100.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease UCH PF00443.29 GAM34011.1 - 9.6e-40 136.7 0.0 1.3e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAM34011.1 - 6.2e-21 74.5 3.9 9.6e-21 73.9 1.4 2.5 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 GAM34011.1 - 3e-17 62.2 0.9 2.6e-09 36.8 0.3 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 GAM34011.1 - 2.1e-16 60.5 0.0 3.7e-14 53.0 0.0 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 GAM34011.1 - 0.066 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain Rep_fac-A_C PF08646.10 GAM34012.1 - 4.3e-56 188.7 3.2 4.2e-55 185.5 2.0 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 GAM34012.1 - 6.9e-37 125.3 0.4 1.8e-36 123.9 0.2 1.9 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 GAM34012.1 - 2.9e-22 78.6 0.0 6.8e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 GAM34012.1 - 9.1e-12 44.8 0.2 2.5e-08 33.8 0.0 3.8 4 1 0 4 4 4 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 GAM34012.1 - 0.0017 18.1 0.3 0.085 12.5 0.1 2.8 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 ADH_zinc_N PF00107.26 GAM34013.1 - 2.1e-22 79.5 0.0 3.1e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM34013.1 - 1.8e-20 74.4 0.0 2.8e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM34013.1 - 3.4e-09 36.6 0.0 5.5e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DEAD PF00270.29 GAM34014.1 - 1.3e-47 161.8 0.0 2.9e-47 160.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM34014.1 - 1.1e-31 109.5 0.0 8.3e-30 103.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM34014.1 - 9.5e-06 25.7 0.0 2.7e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAM34014.1 - 0.023 13.9 0.0 0.048 12.9 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 GAM34014.1 - 0.03 13.7 0.0 0.03 13.7 0.0 2.4 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF2075 PF09848.9 GAM34014.1 - 0.25 10.6 1.0 0.29 10.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Rft-1 PF04506.13 GAM34015.1 - 1.1e-131 440.1 9.6 1.5e-131 439.7 9.6 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 GAM34015.1 - 6.1e-08 32.4 4.2 6.1e-08 32.4 4.2 2.7 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 GAM34015.1 - 1.7e-05 24.2 7.9 1.7e-05 24.2 7.9 2.7 1 1 0 2 2 2 1 Polysaccharide biosynthesis protein OST3_OST6 PF04756.13 GAM34016.1 - 9.8e-105 350.1 0.0 1.2e-104 349.8 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 GAM34016.1 - 0.09 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin HXXEE PF13787.6 GAM34016.1 - 0.64 10.8 4.7 0.21 12.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif FtsJ PF01728.19 GAM34017.1 - 2.1e-34 119.2 0.2 7.6e-34 117.3 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF2935 PF11155.8 GAM34017.1 - 0.051 13.9 4.4 0.076 13.3 1.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) TPR_MLP1_2 PF07926.12 GAM34017.1 - 0.39 10.8 58.8 0.017 15.2 31.0 3.5 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein PSI_PsaF PF02507.15 GAM34017.1 - 0.53 10.1 7.2 0.055 13.3 0.7 2.6 2 1 0 2 2 2 0 Photosystem I reaction centre subunit III GAS PF13851.6 GAM34017.1 - 3.2 7.0 52.2 5.7 6.2 15.9 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 GAM34017.1 - 3.7 7.6 47.5 0.49 10.5 11.9 3.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding ATG7_N PF16420.5 GAM34018.1 - 1.9e-108 362.7 0.1 2.3e-108 362.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 GAM34018.1 - 2e-44 151.8 0.0 3e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 GAM34018.1 - 0.095 12.8 0.0 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase His_biosynth PF00977.21 GAM34019.1 - 7.2e-45 153.2 1.9 3e-44 151.2 1.9 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 GAM34019.1 - 3.9e-21 75.7 0.0 8.6e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I dCMP_cyt_deam_1 PF00383.23 GAM34019.1 - 2.1e-12 46.8 0.0 4.5e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNO PF01174.19 GAM34019.1 - 5.4e-09 36.2 0.0 2.2e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 GAM34019.1 - 1.8e-07 30.9 0.7 7.9e-07 28.9 0.0 2.3 2 1 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain MafB19-deam PF14437.6 GAM34019.1 - 2.6e-05 24.0 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 GAM34019.1 - 7.7e-05 23.3 0.0 0.00017 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DJ-1_PfpI PF01965.24 GAM34019.1 - 0.044 13.6 0.1 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 DJ-1/PfpI family Dus PF01207.17 GAM34019.1 - 0.15 11.1 0.1 0.39 9.7 0.1 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) CoaE PF01121.20 GAM34019.1 - 0.15 11.7 0.2 0.58 9.8 0.0 2.1 3 0 0 3 3 3 0 Dephospho-CoA kinase DWNN PF08783.11 GAM34020.1 - 3.3e-34 117.0 0.0 6.6e-34 116.0 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 GAM34020.1 - 3.7e-08 33.0 5.0 6.8e-08 32.2 5.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 GAM34020.1 - 0.0013 18.5 8.1 0.0027 17.5 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 GAM34020.1 - 0.0021 18.1 0.7 0.0043 17.1 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF966 PF06136.13 GAM34020.1 - 0.012 15.4 4.4 0.023 14.4 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) zf-Nse PF11789.8 GAM34020.1 - 0.2 11.5 4.2 0.43 10.4 4.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Dicty_REP PF05086.12 GAM34020.1 - 0.23 9.4 3.5 0.33 8.9 3.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-RING_2 PF13639.6 GAM34020.1 - 0.35 11.3 6.9 0.74 10.2 6.9 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 GAM34020.1 - 0.51 10.2 5.9 1.3 8.9 5.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Endomucin PF07010.12 GAM34020.1 - 3 7.8 14.4 5.2 7.0 14.4 1.3 1 0 0 1 1 1 0 Endomucin CAML PF14963.6 GAM34020.1 - 5.7 7.0 9.0 10 6.1 9.0 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand zf-C3HC4 PF00097.25 GAM34020.1 - 5.8 6.9 8.7 13 5.8 8.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MCM_bind PF09739.9 GAM34020.1 - 6.2 5.1 11.0 11 4.3 11.0 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor zf-C3HC4_4 PF15227.6 GAM34020.1 - 6.2 7.1 9.0 16 5.8 9.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ODC_AZ PF02100.17 GAM34021.1 - 2.1e-32 111.5 0.0 3.3e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Yippee-Mis18 PF03226.14 GAM34022.1 - 1.2e-22 80.1 0.4 1.7e-22 79.6 0.4 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Transp_Tc5_C PF04236.15 GAM34022.1 - 0.0048 17.2 0.0 0.27 11.6 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase C-terminal domain RIG-I_C-RD PF11648.8 GAM34022.1 - 0.19 12.0 0.6 10 6.4 0.1 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I Ribosomal_S27e PF01667.17 GAM34022.1 - 0.25 11.1 2.3 3.2 7.5 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 SHNi-TPR PF10516.9 GAM34023.1 - 1.3e-10 40.6 1.1 1.3e-10 40.6 1.1 3.0 3 0 0 3 3 3 1 SHNi-TPR MIT PF04212.18 GAM34023.1 - 0.053 13.6 8.7 0.057 13.5 1.8 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Ribosomal_L29 PF00831.23 GAM34023.1 - 0.11 12.5 1.4 0.39 10.7 1.4 2.0 1 0 0 1 1 1 0 Ribosomal L29 protein CCDC-167 PF15188.6 GAM34023.1 - 0.18 12.1 2.9 0.31 11.4 1.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Snapin_Pallidin PF14712.6 GAM34023.1 - 0.35 11.3 5.4 1.2 9.6 1.3 3.3 3 1 0 3 3 3 0 Snapin/Pallidin TPR_3 PF07720.12 GAM34023.1 - 3.1 7.9 10.3 0.38 10.8 0.5 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM34023.1 - 5.1 7.6 5.9 25 5.4 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM34023.1 - 6.7 7.1 7.7 5.4 7.4 0.7 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol_E_B PF04042.16 GAM34024.1 - 1.1e-33 116.4 0.0 1.6e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B TRP PF06011.12 GAM34025.1 - 9.9e-141 469.3 15.3 1.2e-140 469.0 15.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 GAM34025.1 - 3.1e-38 131.3 1.7 5.2e-38 130.5 1.7 1.4 1 0 0 1 1 1 1 ML-like domain Hep_59 PF07052.11 GAM34026.1 - 1.5e-20 73.9 2.7 1.5e-20 73.9 2.7 2.6 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Actin PF00022.19 GAM34027.1 - 1.5e-149 498.1 0.0 1.6e-149 497.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 GAM34027.1 - 0.00053 18.9 0.0 0.71 8.6 0.0 2.9 3 0 0 3 3 3 2 MreB/Mbl protein UDG PF03167.19 GAM34029.1 - 6e-23 81.5 0.1 1e-22 80.8 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Thioredoxin PF00085.20 GAM34030.1 - 9.9e-62 205.4 1.1 2.7e-30 104.4 0.0 4.2 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 GAM34030.1 - 6.9e-49 166.3 0.4 8.7e-38 130.1 0.4 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 GAM34030.1 - 2e-09 37.0 1.5 5e-09 35.7 1.5 1.6 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.6 GAM34030.1 - 7e-08 32.9 0.3 0.0099 16.3 0.0 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAM34030.1 - 1.2e-07 31.9 0.1 0.059 13.7 0.0 4.1 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 GAM34030.1 - 9.5e-07 28.8 0.1 0.0047 16.8 0.0 3.0 3 0 0 3 3 3 2 AhpC/TSA family OST3_OST6 PF04756.13 GAM34030.1 - 1.5e-06 27.8 0.1 0.048 13.0 0.0 3.2 2 1 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 GAM34030.1 - 1.9e-06 27.9 0.0 0.02 15.1 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 GAM34030.1 - 0.00027 20.7 1.0 1.1 9.0 0.1 3.7 3 0 0 3 3 3 1 Redoxin ERp29_N PF07912.13 GAM34030.1 - 0.0017 18.5 0.1 6.7 6.9 0.0 3.8 4 0 0 4 4 4 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.6 GAM34030.1 - 6.2 6.9 9.5 85 3.3 4.4 4.2 3 2 1 4 4 4 0 Thioredoxin SR-25 PF10500.9 GAM34030.1 - 8.9 5.8 7.8 15 5.1 7.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATG22 PF11700.8 GAM34031.1 - 3.1e-199 662.5 11.1 3.6e-199 662.3 11.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 GAM34031.1 - 4.1e-12 45.7 42.9 1.4e-09 37.3 17.0 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 GAM34031.1 - 4.8e-06 25.4 23.8 0.00017 20.3 2.8 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein Med14 PF08638.11 GAM34032.1 - 1.7e-65 220.0 0.2 2.7e-65 219.4 0.2 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 RRM_1 PF00076.22 GAM34033.1 - 6.9e-34 115.5 0.2 1.2e-15 57.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM34033.1 - 4.5e-11 42.7 0.3 0.0003 20.8 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 GAM34033.1 - 0.014 15.4 0.0 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.6 GAM34033.1 - 0.027 14.5 0.0 5.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF2201_N PF13203.6 GAM34033.1 - 0.094 12.3 5.5 0.2 11.2 5.5 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain PRP1_N PF06424.12 GAM34034.1 - 3.6e-36 124.8 7.8 3.6e-36 124.8 7.8 2.2 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal RabGAP-TBC PF00566.18 GAM34034.1 - 1.2e-24 87.2 0.1 8.1e-24 84.5 0.0 2.3 2 1 0 2 2 2 1 Rab-GTPase-TBC domain TPR_14 PF13428.6 GAM34034.1 - 3.4e-23 80.3 31.6 0.00017 22.1 0.4 11.9 4 2 8 12 12 12 7 Tetratricopeptide repeat TPR_19 PF14559.6 GAM34034.1 - 3.6e-21 75.5 11.5 3.4e-06 27.5 0.2 8.7 6 2 3 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAM34034.1 - 1.1e-13 50.1 8.1 0.043 13.9 0.0 8.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAM34034.1 - 5.1e-12 46.2 16.3 1.8e-05 25.3 0.3 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM34034.1 - 1.6e-11 43.4 4.9 0.28 11.5 0.0 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAM34034.1 - 2.3e-08 33.5 4.0 0.03 14.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM34034.1 - 2.9e-07 30.1 4.4 0.87 9.3 0.0 6.5 6 1 1 7 7 7 2 TPR repeat TPR_21 PF09976.9 GAM34034.1 - 1.2e-05 25.2 6.9 1.5e-05 24.8 1.6 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 GAM34034.1 - 3e-05 24.1 3.8 16 6.1 0.0 7.8 8 0 0 8 8 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM34034.1 - 7.6e-05 22.9 0.2 0.01 16.0 0.0 3.6 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAM34034.1 - 0.0032 17.7 6.2 0.13 12.6 0.1 5.5 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM34034.1 - 0.0034 17.5 6.2 1.3 9.3 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM34034.1 - 0.015 15.3 0.8 11 6.3 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM34034.1 - 0.33 11.7 9.2 51 4.8 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat SAGA-Tad1 PF12767.7 GAM34035.1 - 8.7e-46 156.6 0.0 1.9e-45 155.5 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit FUSC_2 PF13515.6 GAM34035.1 - 2.7e-31 108.3 10.0 2.7e-31 108.3 10.0 3.3 2 1 1 3 3 3 2 Fusaric acid resistance protein-like ArAE_2 PF10334.9 GAM34035.1 - 0.0068 16.3 0.7 0.014 15.3 0.2 1.7 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 GAM34035.1 - 0.029 12.9 9.8 2.3 6.7 0.1 3.3 3 0 0 3 3 3 0 Fusaric acid resistance protein family ALMT PF11744.8 GAM34035.1 - 3.2 6.5 19.0 8.6 5.1 11.5 3.4 3 1 0 3 3 3 0 Aluminium activated malate transporter WD40 PF00400.32 GAM34036.1 - 4.7e-28 96.9 25.5 5.1e-05 24.0 0.1 10.4 9 1 1 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM34036.1 - 1.3e-18 67.1 5.1 9.9e-06 25.8 0.0 7.1 4 3 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S18 PF01084.20 GAM34036.1 - 9.4e-14 51.4 0.4 5.4e-13 48.9 0.1 2.4 2 0 0 2 2 2 1 Ribosomal protein S18 PD40 PF07676.12 GAM34036.1 - 2.1e-05 24.3 3.1 4.5 7.3 0.0 6.4 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 GAM34036.1 - 0.00021 20.4 3.3 1.2 8.0 0.0 4.8 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 GAM34036.1 - 0.0015 17.9 0.0 0.0048 16.2 0.0 1.8 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40_3 PF15911.5 GAM34036.1 - 0.0057 16.6 0.0 6.8 6.8 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat WD40_like PF17005.5 GAM34036.1 - 0.049 13.0 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 GAM34036.1 - 0.057 12.1 0.1 0.19 10.4 0.0 1.7 1 1 0 1 1 1 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 GAM34036.1 - 0.087 13.3 1.1 17 6.0 0.0 4.7 4 1 0 4 4 4 0 PQQ-like domain PPR_2 PF13041.6 GAM34037.1 - 4.1e-05 23.7 0.0 0.24 11.6 0.0 3.1 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.20 GAM34037.1 - 0.015 15.5 0.4 0.8 10.1 0.1 3.4 3 0 0 3 3 3 0 PPR repeat PPR_1 PF12854.7 GAM34037.1 - 0.081 12.7 1.8 0.36 10.6 0.2 2.7 3 0 0 3 3 3 0 PPR repeat ELFV_dehydrog PF00208.21 GAM34038.1 - 2.2e-67 227.3 0.0 3.3e-67 226.8 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 GAM34038.1 - 6.7e-17 60.4 0.1 5.1e-11 40.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 GAM34038.1 - 0.015 15.2 0.0 0.051 13.5 0.0 1.8 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Kv2channel PF03521.14 GAM34039.1 - 0.014 14.8 0.4 0.017 14.5 0.3 1.3 1 1 0 1 1 1 0 Kv2 voltage-gated K+ channel TFIIIC_sub6 PF10419.9 GAM34040.1 - 4.3e-21 74.6 0.0 5.3e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Vps62 PF06101.11 GAM34041.1 - 0.00034 19.0 0.6 0.00075 17.9 0.1 1.7 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 PfkB PF00294.24 GAM34041.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Shikimate_dh_N PF08501.11 GAM34043.1 - 2.8e-14 53.1 0.0 5.2e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 GAM34043.1 - 6.7e-05 23.0 0.0 0.00017 21.7 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAM34043.1 - 0.0035 17.6 0.0 0.0068 16.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 GAM34044.1 - 2.6e-35 122.0 55.5 2e-34 119.1 35.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM34044.1 - 5.7e-10 38.6 11.6 5.7e-10 38.6 11.6 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 GAM34044.1 - 6.6e-06 25.7 2.0 6.6e-06 25.7 2.0 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Acyl-CoA_dh_1 PF00441.24 GAM34045.1 - 8.9e-23 81.2 0.1 1.4e-22 80.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAM34045.1 - 4.7e-09 36.9 0.0 1.6e-08 35.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAM34045.1 - 1.4e-06 28.4 0.0 2.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAM34045.1 - 7.3e-05 23.1 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cupin_8 PF13621.6 GAM34046.1 - 2e-08 34.3 0.0 2e-08 34.3 0.0 2.5 3 0 0 3 3 3 1 Cupin-like domain JmjC PF02373.22 GAM34046.1 - 2.7e-08 34.2 0.0 2.4e-07 31.2 0.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase JHD PF17811.1 GAM34046.1 - 3e-08 34.1 0.2 7.2e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 Jumonji helical domain PHD PF00628.29 GAM34046.1 - 6.4e-08 32.4 7.0 6.4e-08 32.4 7.0 2.6 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 GAM34046.1 - 0.017 14.7 5.6 0.019 14.5 3.6 2.3 2 0 0 2 2 2 0 PHD-finger Zn_clus PF00172.18 GAM34046.1 - 3.7 7.7 29.1 0.47 10.6 6.7 3.1 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 GAM34047.1 - 1.5e-14 53.5 0.1 2.9e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM34047.1 - 6.4e-05 22.5 0.0 6.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM34047.1 - 0.099 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif STIMATE PF12400.8 GAM34048.1 - 7e-40 136.5 6.1 8.4e-40 136.2 5.1 1.6 2 0 0 2 2 2 1 STIMATE family TMEM43 PF07787.12 GAM34048.1 - 5.1 6.4 5.4 10 5.4 5.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 43 ANAPC4_WD40 PF12894.7 GAM34049.1 - 5.9e-06 26.5 0.1 0.85 10.0 0.0 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAM34049.1 - 3.3e-05 24.6 0.1 0.057 14.3 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Nucleoporin_N PF08801.11 GAM34049.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like TLP1_add_C PF18313.1 GAM34050.1 - 8.6e-24 83.3 0.0 1.3e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain Peptidase_S10 PF00450.22 GAM34052.1 - 6e-93 312.5 1.2 8.3e-93 312.1 1.2 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_1 PF00561.20 GAM34053.1 - 1.7e-18 67.2 0.0 3.3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM34053.1 - 8.1e-13 49.5 0.4 1.1e-12 49.1 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM34053.1 - 1.9e-12 47.0 0.0 2.7e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 GAM34053.1 - 0.092 11.4 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) ECH_1 PF00378.20 GAM34054.1 - 2.1e-49 168.1 0.0 2.6e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM34054.1 - 2.1e-26 93.2 0.2 1.9e-22 80.2 0.2 2.5 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 GAM34054.1 - 0.0007 19.6 0.0 0.0091 16.0 0.0 2.1 1 1 1 2 2 2 1 Peptidase family S49 MM_CoA_mutase PF01642.22 GAM34054.1 - 0.037 12.6 0.1 0.051 12.1 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase SDH_sah PF01972.16 GAM34054.1 - 0.058 12.4 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Hexokinase_2 PF03727.16 GAM34055.1 - 5.1e-82 274.9 0.0 6.9e-82 274.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 GAM34055.1 - 1.4e-72 243.8 0.0 1.8e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase SIR2 PF02146.17 GAM34056.1 - 1.4e-54 184.7 0.0 2.1e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 GAM34056.1 - 0.046 13.5 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain COG4 PF08318.12 GAM34057.1 - 9.4e-124 412.8 0.0 1.3e-123 412.4 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein DUF4893 PF16233.5 GAM34057.1 - 0.11 12.1 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4893) Ammonium_transp PF00909.21 GAM34058.1 - 4.1e-115 384.7 28.7 4.7e-115 384.5 28.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF2946 PF11162.8 GAM34058.1 - 0.084 13.5 2.2 25 5.6 1.2 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2946) Glyco_hydro_cc PF11790.8 GAM34059.1 - 1.6e-41 142.5 0.2 2.2e-41 142.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core E1-E2_ATPase PF00122.20 GAM34060.1 - 2.8e-46 157.3 0.3 2.8e-46 157.3 0.3 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAM34060.1 - 1.1e-43 149.0 0.3 1.1e-43 149.0 0.3 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAM34060.1 - 1e-21 78.2 0.6 2.6e-20 73.6 0.6 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM34060.1 - 6.9e-20 70.5 0.0 1.6e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAM34060.1 - 2.2e-13 50.1 0.0 4.3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAM34060.1 - 1.1e-05 25.4 2.6 2.9e-05 23.9 0.5 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DAGK_cat PF00781.24 GAM34060.1 - 0.027 14.1 1.5 0.23 11.1 0.1 2.8 2 1 1 3 3 3 0 Diacylglycerol kinase catalytic domain Rad21_Rec8_N PF04825.13 GAM34061.1 - 1.7e-37 127.9 0.2 1.9e-37 127.8 0.2 1.0 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 GAM34062.1 - 1.5e-09 37.0 0.0 4.4e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein MARVEL PF01284.23 GAM34063.1 - 0.79 9.7 11.4 5.6 7.0 11.6 2.1 1 1 0 1 1 1 0 Membrane-associating domain MFS_1 PF07690.16 GAM34064.1 - 5.8e-41 140.6 35.6 6.4e-40 137.2 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM34064.1 - 4.7e-05 22.0 2.9 8.3e-05 21.2 2.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Flavokinase PF01687.17 GAM34065.1 - 1.4e-28 99.5 0.0 2.8e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.18 GAM34065.1 - 0.0097 16.0 9.2 0.023 14.8 9.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Indigoidine_A PF04227.12 GAM34066.1 - 2.7e-122 407.7 0.4 3.7e-122 407.3 0.4 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 GAM34066.1 - 3.8e-07 29.7 0.2 3.2e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Ribophorin_I PF04597.14 GAM34067.1 - 2.3e-151 505.0 0.0 2.6e-151 504.8 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Ank_2 PF12796.7 GAM34068.1 - 3e-43 146.3 2.9 1.2e-12 48.2 0.2 4.9 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM34068.1 - 6.5e-37 125.4 4.3 2.1e-08 34.5 0.0 6.3 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM34068.1 - 1.9e-27 92.3 6.5 0.00024 21.3 0.0 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 GAM34068.1 - 3.1e-27 93.8 9.5 5.9e-05 23.3 0.0 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 GAM34068.1 - 2.9e-25 88.0 12.0 6.9e-06 26.2 0.3 7.6 2 1 6 8 8 8 7 Ankyrin repeats (many copies) TolA PF06519.11 GAM34068.1 - 0.0005 20.2 0.6 1.7 8.9 0.1 3.5 2 2 1 4 4 4 2 TolA C-terminal VTC PF09359.10 GAM34069.1 - 1.9e-99 332.6 0.0 2.8e-99 332.0 0.0 1.3 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 GAM34069.1 - 9.3e-15 54.8 3.7 9.6e-14 51.6 3.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 GAM34069.1 - 1.6e-11 44.8 12.3 2.6e-05 24.3 0.2 3.8 3 1 1 4 4 4 3 SPX domain RCR PF12273.8 GAM34069.1 - 0.086 13.5 0.3 0.18 12.4 0.3 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TauE PF01925.19 GAM34069.1 - 0.089 12.4 0.7 0.14 11.7 0.7 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE MCM PF00493.23 GAM34070.1 - 3.8e-102 340.2 0.0 5.3e-102 339.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAM34070.1 - 2.2e-38 130.9 0.9 4.3e-38 130.0 0.9 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAM34070.1 - 8.4e-29 99.8 2.9 1.9e-28 98.7 2.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAM34070.1 - 1.4e-18 67.4 0.1 2e-16 60.5 0.0 2.7 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 GAM34070.1 - 2.2e-06 27.7 0.0 7.7e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAM34070.1 - 5.3e-06 26.0 0.0 0.00015 21.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAM34070.1 - 0.0009 19.1 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAM34070.1 - 0.15 11.8 0.1 4.7 6.9 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_16 PF13191.6 GAM34070.1 - 0.51 10.7 3.1 1.8 8.9 0.0 3.2 2 2 0 2 2 2 0 AAA ATPase domain RSN1_TM PF13967.6 GAM34071.1 - 5.1e-45 153.0 0.6 5.1e-45 153.0 0.6 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport RSN1_7TM PF02714.15 GAM34071.1 - 2.2e-40 138.7 20.3 2.2e-40 138.7 20.3 2.4 2 1 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 GAM34071.1 - 4.3e-28 98.7 3.9 5.9e-18 65.7 0.1 2.6 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 GAM34071.1 - 9.1e-13 48.2 0.0 2.8e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter SPT_ssu-like PF11779.8 GAM34071.1 - 0.35 10.5 3.1 17 5.1 1.5 3.0 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like ATP-synt_B PF00430.18 GAM34071.1 - 0.37 10.9 9.9 0.98 9.5 9.9 1.7 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) TLV_coat PF00429.19 GAM34071.1 - 0.89 8.1 2.5 14 4.2 4.1 1.9 2 0 0 2 2 2 0 ENV polyprotein (coat polyprotein) PhoR PF11808.8 GAM34071.1 - 0.98 9.9 0.0 0.98 9.9 0.0 3.6 3 1 1 4 4 4 0 Phosphate regulon sensor protein PhoR Acetyltransf_1 PF00583.25 GAM34072.1 - 0.00012 22.2 0.0 0.00022 21.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM34072.1 - 0.0098 16.3 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM34072.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cytochrom_NNT PF03264.14 GAM34072.1 - 0.072 12.8 0.2 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Acetyltransf_13 PF13880.6 GAM34072.1 - 0.089 12.8 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase FR47 PF08445.10 GAM34072.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein CSTF2_hinge PF14327.6 GAM34073.1 - 1.6e-32 111.7 1.3 1.6e-32 111.7 1.3 2.6 4 0 0 4 4 4 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 GAM34073.1 - 1.4e-19 69.7 0.0 2.1e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 GAM34073.1 - 9.7e-17 60.3 14.6 9.7e-17 60.3 14.6 2.5 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_occluded PF16842.5 GAM34073.1 - 0.013 15.3 0.0 0.038 13.8 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_7 PF16367.5 GAM34073.1 - 0.016 15.3 0.1 0.82 9.8 0.0 2.4 1 1 1 2 2 2 0 RNA recognition motif Spo7_2_N PF15407.6 GAM34073.1 - 0.025 14.2 0.0 0.074 12.7 0.0 1.8 2 0 0 2 2 2 0 Sporulation protein family 7 RRM_Rrp7 PF17799.1 GAM34073.1 - 0.09 12.6 0.0 8.5 6.2 0.0 2.2 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_5 PF13893.6 GAM34073.1 - 0.18 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Band_7 PF01145.25 GAM34074.1 - 4.9e-22 78.8 6.6 9.8e-22 77.8 6.6 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family Ank_2 PF12796.7 GAM34075.1 - 0.0021 18.6 0.1 1.6 9.4 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Methyltransf_25 PF13649.6 GAM34075.1 - 0.02 15.6 0.0 0.05 14.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ank_4 PF13637.6 GAM34075.1 - 0.031 14.9 0.3 20 5.9 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) SNF2_N PF00176.23 GAM34076.1 - 3.7e-15 55.5 0.0 1.1e-09 37.5 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 GAM34076.1 - 2.4e-13 50.1 0.1 1.8e-12 47.2 0.0 2.5 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 GAM34076.1 - 0.00013 22.3 0.1 0.00024 21.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 GAM34076.1 - 0.0092 15.8 5.7 0.028 14.3 5.7 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAM34076.1 - 2.6 8.1 11.4 0.28 11.3 4.5 2.5 2 0 0 2 2 2 0 RING-type zinc-finger 2Fe-2S_thioredx PF01257.19 GAM34077.1 - 7.1e-60 201.1 0.1 9.9e-60 200.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SpoVS PF04232.12 GAM34077.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) A_deaminase PF00962.22 GAM34078.1 - 1.5e-78 264.4 0.0 1.7e-78 264.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2724 PF10893.8 GAM34080.1 - 0.045 13.6 0.1 0.18 11.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) DUF717 PF05338.12 GAM34080.1 - 0.1 12.7 0.1 0.46 10.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF717) EHN PF06441.12 GAM34081.1 - 8.5e-32 109.7 0.1 1.6e-31 108.8 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 GAM34081.1 - 1.2e-09 38.2 0.0 2.3e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold RHH_3 PF12651.7 GAM34081.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain Abhydrolase_6 PF12697.7 GAM34081.1 - 1.6 9.2 6.7 32 5.0 6.7 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Sua5_yciO_yrdC PF01300.18 GAM34082.1 - 7e-55 185.3 0.0 1.1e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 GAM34082.1 - 3.4e-32 111.8 0.0 6.6e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Mon1 PF03164.14 GAM34083.1 - 8.4e-156 519.1 0.0 9.7e-156 518.9 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 DUF2683 PF10884.8 GAM34083.1 - 0.57 10.5 1.9 1.6 9.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) Dopey_N PF04118.14 GAM34084.1 - 4.2e-118 393.9 0.0 2.7e-117 391.3 0.0 2.5 2 0 0 2 2 2 1 Dopey, N-terminal EHN PF06441.12 GAM34085.1 - 4.9e-26 91.2 0.2 8.6e-26 90.4 0.2 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 GAM34085.1 - 5.6e-12 45.8 0.1 9.6e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM34085.1 - 0.1 13.2 1.5 0.32 11.6 1.5 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family NBD_C PF17042.5 GAM34085.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain Sugar_tr PF00083.24 GAM34086.1 - 7.4e-92 308.6 19.2 9.1e-92 308.3 19.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM34086.1 - 6.6e-30 104.2 38.6 4.2e-24 85.1 19.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAM34086.1 - 8.2e-05 21.1 16.0 0.0021 16.4 8.1 3.2 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Prefoldin PF02996.17 GAM34087.1 - 0.025 14.5 1.1 0.033 14.1 1.1 1.1 1 0 0 1 1 1 0 Prefoldin subunit Fib_alpha PF08702.10 GAM34087.1 - 0.04 14.1 0.4 0.052 13.7 0.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Retrotrans_gag PF03732.17 GAM34087.1 - 0.05 13.9 0.4 0.088 13.1 0.4 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein DUF1664 PF07889.12 GAM34087.1 - 0.76 9.8 3.2 0.41 10.7 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-HIT PF04438.16 GAM34088.1 - 1.4e-10 40.8 8.3 2.3e-10 40.1 8.3 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF5393 PF17371.2 GAM34088.1 - 0.0078 14.4 1.9 0.0092 14.2 1.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5393) MSP1_C PF07462.11 GAM34088.1 - 0.57 8.8 5.2 0.74 8.4 5.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Sof1 PF04158.14 GAM34088.1 - 2.4 8.5 6.6 1.2 9.5 1.1 2.3 2 0 0 2 2 2 0 Sof1-like domain MBOAT PF03062.19 GAM34089.1 - 9.5e-43 146.9 20.2 2.7e-32 112.5 10.2 2.3 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Acylphosphatase PF00708.18 GAM34090.1 - 3.3e-22 78.7 0.4 1.8e-21 76.3 0.0 1.8 2 0 0 2 2 2 1 Acylphosphatase BLUF PF04940.12 GAM34090.1 - 0.0097 16.0 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 1 Sensors of blue-light using FAD AOX PF01786.17 GAM34091.1 - 6e-99 330.0 0.3 7.2e-99 329.7 0.3 1.1 1 0 0 1 1 1 1 Alternative oxidase Peptidase_S66C PF17676.1 GAM34091.1 - 0.14 12.7 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 LD-carboxypeptidase C-terminal domain KAR9 PF08580.10 GAM34093.1 - 1e-251 837.4 5.4 1e-251 837.4 5.4 2.5 2 1 0 2 2 2 1 Yeast cortical protein KAR9 Spectrin PF00435.21 GAM34093.1 - 0.27 11.8 7.2 3.4 8.2 0.1 4.2 4 1 0 4 4 4 0 Spectrin repeat Snf7 PF03357.21 GAM34093.1 - 0.46 10.1 2.5 8.4 6.0 2.7 2.5 1 1 0 1 1 1 0 Snf7 TauD PF02668.16 GAM34096.1 - 6e-33 114.8 0.0 8.4e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TSSC4 PF15264.6 GAM34096.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 MafB19-deam PF14437.6 GAM34098.1 - 4.6e-10 39.4 0.0 8.8e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 GAM34098.1 - 1.1e-08 34.9 0.0 2.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Fungal_trans PF04082.18 GAM34098.1 - 6.6e-06 25.3 0.2 1.7e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Amido_AtzD_TrzD PF09663.10 GAM34099.1 - 2.1e-119 398.8 1.7 2.5e-119 398.5 1.7 1.0 1 0 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Amidase PF01425.21 GAM34100.1 - 4.7e-73 246.7 0.0 5.9e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Amidase MOSC PF03473.17 GAM34101.1 - 3.9e-23 81.9 0.0 9.8e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.27 GAM34101.1 - 1.6e-11 44.0 1.7 3.5e-11 42.9 1.7 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 GAM34101.1 - 1.9e-09 37.2 0.0 4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 3-alpha domain NAD_binding_1 PF00175.21 GAM34101.1 - 0.0059 17.2 0.4 0.25 12.0 0.0 2.9 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAM34101.1 - 0.04 14.0 0.3 0.66 10.1 0.1 2.3 1 1 1 2 2 2 0 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 GAM34101.1 - 0.072 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Lactonase PF10282.9 GAM34103.1 - 3.7e-81 273.1 0.0 4.6e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.6 GAM34103.1 - 4.9e-05 23.7 3.4 0.074 13.6 0.1 4.2 4 1 0 4 4 4 2 PQQ-like domain GAGA_bind PF06217.12 GAM34104.1 - 0.038 14.3 0.1 0.046 14.0 0.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Helo_like_N PF17111.5 GAM34105.1 - 2.2e-12 46.8 3.7 4.4e-12 45.8 3.7 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins PMEI PF04043.15 GAM34105.1 - 0.18 12.1 6.5 4.1 7.7 2.8 2.5 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor MFS_1 PF07690.16 GAM34106.1 - 6.2e-40 137.2 50.3 1.3e-39 136.1 50.3 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM34106.1 - 1e-07 31.2 16.0 1e-07 31.2 16.0 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter PI-PLC-X PF00388.19 GAM34106.1 - 0.0069 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain UBM PF14377.6 GAM34106.1 - 0.06 12.8 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin binding region RebB PF11747.8 GAM34106.1 - 0.77 9.9 8.2 0.075 13.1 2.8 2.1 2 0 0 2 2 2 0 Killing trait Zn_clus PF00172.18 GAM34107.1 - 7.5e-05 22.8 10.8 0.00027 21.0 10.8 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM34107.1 - 0.0006 18.9 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AbiEii PF08843.11 GAM34108.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.5 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system NACHT PF05729.12 GAM34109.1 - 7.7e-08 32.4 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAM34109.1 - 2.2e-06 28.2 0.0 4.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM34109.1 - 0.018 15.3 0.0 0.05 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAM34109.1 - 0.024 15.0 0.0 0.078 13.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 GAM34109.1 - 0.063 13.3 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 GAM34109.1 - 0.09 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 GAM34109.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Methyltransf_33 PF10017.9 GAM34110.1 - 3.1e-73 246.6 0.0 5.1e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FAD_binding_3 PF01494.19 GAM34110.1 - 2.6e-34 119.0 0.0 5.6e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAM34110.1 - 7e-30 104.2 0.0 1.5e-29 103.2 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 GAM34111.1 - 6.5e-40 137.8 0.2 8.2e-40 137.5 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 GAM34111.1 - 2.8e-11 43.2 0.2 8.6e-11 41.6 0.2 1.9 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.6 GAM34111.1 - 2.8e-06 27.5 0.3 7e-06 26.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM34111.1 - 3.6e-05 23.0 0.2 6e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM34111.1 - 4.4e-05 22.9 0.5 8.5e-05 21.9 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAM34111.1 - 6e-05 22.4 0.1 0.00015 21.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 GAM34111.1 - 0.00026 20.4 0.2 0.0014 17.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM34111.1 - 0.00031 19.9 0.6 0.0041 16.2 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 GAM34111.1 - 0.00063 19.1 0.1 0.0013 18.0 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 GAM34111.1 - 0.0014 18.1 3.1 0.061 12.7 3.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM34111.1 - 0.0045 17.5 0.5 0.01 16.4 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM34111.1 - 0.023 13.8 0.6 0.15 11.1 0.3 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 GAM34111.1 - 0.03 14.3 0.3 0.15 12.0 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 GAM34111.1 - 0.062 12.0 0.4 0.11 11.1 0.4 1.4 1 0 0 1 1 1 0 HI0933-like protein Rieske_2 PF13806.6 GAM34111.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain AlaDh_PNT_C PF01262.21 GAM34111.1 - 0.14 11.4 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PS_Dcarbxylase PF02666.15 GAM34112.1 - 2.9e-56 190.2 0.0 3.6e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase AAA PF00004.29 GAM34113.1 - 4.1e-16 59.6 0.0 8.2e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM34113.1 - 2.5e-06 27.8 0.2 3e-05 24.3 0.1 2.8 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 GAM34113.1 - 7.8e-05 23.1 0.2 0.00046 20.6 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GAM34113.1 - 0.00059 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 GAM34113.1 - 0.011 15.6 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAM34113.1 - 0.017 15.5 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAM34113.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 GAM34113.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 GAM34113.1 - 0.13 12.4 0.0 0.42 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAM34113.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 GAM34113.1 - 0.17 11.8 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain SlyX PF04102.12 GAM34114.1 - 0.46 11.1 4.6 2.7 8.7 4.6 2.5 1 0 0 1 1 1 0 SlyX Mito_carr PF00153.27 GAM34115.1 - 2e-61 203.9 0.8 4.7e-20 71.3 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.7 GAM34116.1 - 1.2e-08 34.7 0.0 2.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM34116.1 - 0.00046 20.0 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain HA2 PF04408.23 GAM34117.1 - 3e-22 78.9 0.1 7.5e-22 77.7 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAM34117.1 - 5.8e-14 52.2 0.0 1.2e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAM34117.1 - 1.8e-11 44.4 0.0 4.1e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAM34117.1 - 0.00077 19.8 0.0 0.0026 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 GAM34117.1 - 0.002 17.9 0.0 0.0065 16.3 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.6 GAM34117.1 - 0.0032 17.2 0.0 0.0078 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM34117.1 - 0.031 14.2 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 GAM34117.1 - 0.033 13.5 0.0 0.092 12.1 0.0 1.6 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 GAM34117.1 - 0.034 14.7 0.0 0.094 13.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 GAM34117.1 - 0.043 14.2 0.0 0.15 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM34117.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Complex1_LYR_2 PF13233.6 GAM34118.1 - 7.1e-21 74.8 0.1 9e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 GAM34118.1 - 1.1e-08 35.0 0.0 2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MTS PF05175.14 GAM34119.1 - 4.3e-05 23.1 0.0 7.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain rRNA_methylase PF06962.12 GAM34119.1 - 0.057 13.4 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative rRNA methylase LSM PF01423.22 GAM34120.1 - 3.5e-18 65.0 0.0 4.5e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAM34120.1 - 0.0011 19.1 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain F-box-like PF12937.7 GAM34121.1 - 0.00067 19.5 1.4 0.0011 18.8 0.3 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAM34121.1 - 0.04 13.8 0.6 0.098 12.6 0.6 1.7 1 0 0 1 1 1 0 F-box domain GTP_EFTU PF00009.27 GAM34122.1 - 3.4e-07 30.0 0.0 8.6e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 GAM34122.1 - 0.017 15.5 0.1 0.062 13.7 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 GAM34122.1 - 0.056 13.2 0.5 0.41 10.4 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 GAM34122.1 - 0.16 11.9 0.7 5.9 6.8 0.1 2.5 2 1 0 2 2 2 0 RsgA GTPase zf-C2H2_4 PF13894.6 GAM34123.1 - 0.00012 22.6 2.0 0.11 13.3 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM34123.1 - 0.001 19.4 2.8 0.052 14.0 0.1 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type Ogr_Delta PF04606.12 GAM34123.1 - 0.048 13.6 0.4 0.11 12.5 0.4 1.6 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Pkr1 PF08636.10 GAM34124.1 - 6.2e-32 109.6 5.2 7.8e-32 109.2 5.2 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Mem_trans PF03547.18 GAM34124.1 - 1.5e-05 23.6 0.0 1.8e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Membrane transport protein CHD5 PF04420.14 GAM34124.1 - 0.022 14.6 0.3 0.036 13.9 0.3 1.3 1 0 0 1 1 1 0 CHD5-like protein OAD_gamma PF04277.13 GAM34124.1 - 0.023 15.3 0.0 0.06 13.9 0.0 1.8 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain FHIPEP PF00771.20 GAM34124.1 - 0.047 12.2 0.1 0.054 12.0 0.1 1.1 1 0 0 1 1 1 0 FHIPEP family NEMP PF10225.9 GAM34124.1 - 0.15 11.8 1.5 0.25 11.0 1.5 1.5 1 1 0 1 1 1 0 NEMP family Kei1 PF08552.11 GAM34124.1 - 0.25 11.2 7.0 0.52 10.2 7.0 1.7 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4834 PF16118.5 GAM34124.1 - 0.26 12.3 5.2 2.3 9.2 5.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Nucleo_P87 PF07267.11 GAM34124.1 - 2.5 6.9 6.0 2.9 6.6 6.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ANAPC2 PF08672.11 GAM34125.1 - 3.9e-23 81.7 0.0 1.4e-22 79.9 0.0 2.1 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Cullin PF00888.22 GAM34125.1 - 8.1e-23 80.9 0.1 1.7e-22 79.8 0.1 1.4 1 0 0 1 1 1 1 Cullin family DIOX_N PF14226.6 GAM34126.1 - 3.1e-18 66.7 0.0 7.2e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM34126.1 - 2.8e-15 56.7 0.0 5.1e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 GAM34127.1 - 9.7e-69 228.0 24.2 1e-16 61.2 1.3 8.5 2 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM34127.1 - 1.3e-53 178.7 15.9 3.9e-10 40.1 0.1 9.6 5 1 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM34127.1 - 5.9e-47 152.2 6.6 0.0012 19.1 0.0 14.2 15 0 0 15 15 15 10 Ankyrin repeat Ank_5 PF13857.6 GAM34127.1 - 2.6e-42 142.3 16.8 2.4e-08 34.1 0.2 11.0 6 3 5 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.30 GAM34127.1 - 7.1e-41 136.9 18.6 8.5e-05 22.8 0.1 12.9 12 0 0 12 12 12 8 Ankyrin repeat CorA PF01544.18 GAM34127.1 - 8.8e-12 44.9 0.0 2.9e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Nitro_FeMo-Co PF02579.17 GAM34127.1 - 0.0078 16.5 4.4 1.7 9.0 0.2 4.3 2 1 2 4 4 4 1 Dinitrogenase iron-molybdenum cofactor MFS_1 PF07690.16 GAM34128.1 - 1.5e-33 116.2 39.9 2.2e-33 115.7 39.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DSBA PF01323.20 GAM34128.1 - 1.7e-23 83.4 0.0 2.5e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 DSBA-like thioredoxin domain FMO-like PF00743.19 GAM34128.1 - 1.7e-19 69.6 0.0 2.3e-09 36.3 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAM34128.1 - 9.3e-08 31.7 0.8 3.3e-06 26.6 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MFS_4 PF06779.14 GAM34128.1 - 5e-06 26.1 4.4 5e-06 26.1 4.4 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Pyr_redox_2 PF07992.14 GAM34128.1 - 0.00018 20.9 0.0 0.06 12.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM34128.1 - 0.00078 19.5 1.5 0.031 14.3 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAM34128.1 - 0.0027 17.9 0.0 0.0076 16.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAM34128.1 - 0.0033 16.6 0.0 0.57 9.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Orf78 PF06024.12 GAM34128.1 - 0.027 14.8 0.0 0.055 13.8 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) DAO PF01266.24 GAM34128.1 - 0.094 12.3 0.2 1.1 8.7 0.3 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase TraC PF07820.12 GAM34129.1 - 0.85 10.0 0.0 0.85 10.0 0.0 3.5 4 0 0 4 4 4 0 TraC-like protein Ribosomal_L16 PF00252.18 GAM34130.1 - 5e-43 146.3 0.1 6.4e-43 145.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e p450 PF00067.22 GAM34131.1 - 1.8e-32 112.7 0.0 3.8e-32 111.6 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 FAD_binding_4 PF01565.23 GAM34131.1 - 1.3e-13 50.9 2.1 5.2e-13 48.9 1.9 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAM34131.1 - 0.0011 19.0 0.0 0.0034 17.5 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 GAM34132.1 - 4.5e-23 81.5 2.8 2.2e-22 79.3 3.1 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAM34132.1 - 0.029 14.5 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like adh_short PF00106.25 GAM34133.1 - 2.4e-15 56.5 0.0 2.1e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 GAM34133.1 - 0.0013 18.6 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM34133.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family LEH PF07858.12 GAM34133.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain p450 PF00067.22 GAM34134.1 - 1.2e-17 63.9 0.0 3.9e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 Ank_2 PF12796.7 GAM34135.1 - 6.6e-21 74.7 0.0 2e-07 31.5 0.0 4.3 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM34135.1 - 4.3e-14 51.2 0.0 0.00099 19.4 0.0 5.9 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 GAM34135.1 - 2.6e-13 50.2 1.0 0.00017 22.1 0.0 5.1 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM34135.1 - 2e-11 43.8 0.1 0.0041 17.5 0.0 5.1 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAM34135.1 - 2.6e-08 34.0 0.1 0.00065 19.9 0.0 4.1 3 2 2 5 5 5 2 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 GAM34135.1 - 0.00097 18.5 0.1 0.0019 17.5 0.1 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_13 PF13166.6 GAM34136.1 - 3.2 6.3 21.1 1.8 7.1 15.5 2.0 2 0 0 2 2 2 0 AAA domain DUF948 PF06103.11 GAM34136.1 - 7.5 6.9 7.6 1.5 9.1 2.3 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Clat_adaptor_s PF01217.20 GAM34137.1 - 4.7e-12 46.0 0.0 6.7e-11 42.3 0.1 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain NFACT-C PF11923.8 GAM34138.1 - 5e-34 116.4 0.0 5e-34 116.4 0.0 3.8 3 0 0 3 3 3 1 NFACT protein C-terminal domain FbpA PF05833.11 GAM34138.1 - 2.7e-33 115.4 11.8 2.7e-33 115.4 11.8 2.5 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 GAM34138.1 - 5.3e-26 91.4 0.0 2.1e-25 89.5 0.0 2.1 2 0 0 2 2 2 1 NFACT protein RNA binding domain DEAD PF00270.29 GAM34139.1 - 8e-23 81.1 0.0 1.9e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM34139.1 - 7.4e-22 77.8 0.0 3.2e-19 69.3 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RQC PF09382.10 GAM34139.1 - 1.7e-17 63.2 0.0 3.8e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 GAM34139.1 - 2.1e-14 54.0 11.5 2.1e-14 54.0 11.5 2.1 2 0 0 2 2 2 1 RecQ zinc-binding HRDC PF00570.23 GAM34139.1 - 3.3e-09 36.6 0.6 9.5e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 HRDC domain ResIII PF04851.15 GAM34139.1 - 2.3e-08 34.2 0.0 5.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1408 PF07193.11 GAM34139.1 - 0.13 12.4 0.1 0.41 10.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) MRP-S27 PF10037.9 GAM34139.1 - 0.29 9.9 1.4 0.48 9.2 1.4 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 CENP-K PF11802.8 GAM34140.1 - 9.5e-09 35.2 2.7 4.7e-05 23.1 3.3 2.4 2 1 0 2 2 2 2 Centromere-associated protein K GAS PF13851.6 GAM34140.1 - 0.029 13.7 7.7 0.063 12.6 1.0 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FliJ PF02050.16 GAM34140.1 - 0.061 13.6 11.7 0.069 13.4 1.9 2.8 2 1 0 2 2 2 0 Flagellar FliJ protein GCS2 PF04107.13 GAM34140.1 - 0.093 12.1 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) CEP63 PF17045.5 GAM34140.1 - 0.14 12.1 7.9 0.021 14.7 3.3 1.8 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa DUF745 PF05335.13 GAM34140.1 - 0.14 11.9 7.4 0.049 13.4 4.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 GAM34140.1 - 0.14 11.7 11.1 0.082 12.5 4.8 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit Fez1 PF06818.15 GAM34140.1 - 0.19 12.2 9.6 0.13 12.7 2.8 2.3 2 0 0 2 2 2 0 Fez1 Prominin PF05478.11 GAM34140.1 - 0.62 7.9 3.5 3.2 5.6 0.1 2.1 2 0 0 2 2 2 0 Prominin Sec8_exocyst PF04048.14 GAM34140.1 - 1.4 8.8 4.4 0.76 9.7 0.8 2.3 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain DUF4407 PF14362.6 GAM34140.1 - 1.5 8.1 15.9 0.032 13.6 7.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 GAM34140.1 - 1.5 8.8 3.8 3.8 7.6 0.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Cdh1_DBD_1 PF18196.1 GAM34140.1 - 1.6 9.1 8.2 0.22 11.8 0.3 2.8 2 1 1 3 3 3 0 Chromodomain helicase DNA-binding domain 1 HIP1_clath_bdg PF16515.5 GAM34140.1 - 3.8 8.2 9.4 0.87 10.2 2.9 2.7 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3450 PF11932.8 GAM34140.1 - 4.2 6.6 9.7 0.77 9.0 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Apolipoprotein PF01442.18 GAM34140.1 - 5.1 6.9 15.2 40 4.0 14.1 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain SlyX PF04102.12 GAM34140.1 - 6.2 7.5 8.5 10 6.8 0.1 3.3 3 1 0 3 3 2 0 SlyX Spc7 PF08317.11 GAM34140.1 - 7.5 5.3 11.0 1.4 7.7 5.8 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4763 PF15960.5 GAM34140.1 - 8.6 5.6 14.3 3.7 6.8 5.2 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4763) CorA PF01544.18 GAM34140.1 - 9 5.5 8.7 53 3.0 8.7 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Abhydrolase_1 PF00561.20 GAM34141.1 - 3.2e-16 59.8 0.0 2.6e-15 56.8 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM34141.1 - 3.2e-08 33.1 0.0 1.4e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Pyridoxal_deC PF00282.19 GAM34142.1 - 2e-25 89.3 0.0 3.8e-25 88.4 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 GAM34142.1 - 0.0012 18.1 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAM34142.1 - 0.016 14.5 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 GAM34142.1 - 0.14 11.1 0.0 0.31 9.9 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V DUF4110 PF13422.6 GAM34143.1 - 3e-32 110.5 4.5 3e-32 110.5 4.5 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 GAM34143.1 - 1.1e-28 98.9 11.0 6.3e-08 32.5 0.0 6.3 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM34143.1 - 6.1e-24 83.8 12.7 1.1e-08 35.2 0.1 6.7 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM34143.1 - 1.4e-16 60.1 5.9 5.1e-06 26.3 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 GAM34143.1 - 1.4e-15 57.0 4.9 0.0045 17.2 0.1 5.4 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 GAM34143.1 - 9.4e-15 53.9 1.0 0.00013 21.4 0.0 5.2 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 GAM34143.1 - 9.7e-13 47.5 8.3 0.0016 18.3 0.0 6.0 6 1 0 6 6 6 4 Kelch motif KH_1 PF00013.29 GAM34144.1 - 3.5e-43 145.3 3.9 2.2e-17 62.6 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GAM34144.1 - 2e-10 40.3 2.3 0.017 14.9 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 GAM34144.1 - 2.2e-05 24.4 8.3 0.19 11.8 0.2 3.3 3 0 0 3 3 3 3 NusA-like KH domain KH_4 PF13083.6 GAM34144.1 - 6e-05 22.8 0.3 0.43 10.5 0.1 3.3 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 GAM34144.1 - 0.00028 20.8 0.0 0.021 14.8 0.0 2.4 2 0 0 2 2 2 1 KH-like RNA-binding domain Tannase PF07519.11 GAM34147.1 - 2.2e-114 383.0 3.0 2.6e-114 382.7 3.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 GAM34147.1 - 0.053 13.0 0.1 16 4.9 0.0 3.0 3 0 0 3 3 3 0 Prolyl oligopeptidase family Thioredoxin PF00085.20 GAM34148.1 - 1.4e-26 92.5 0.1 5.2e-26 90.6 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 GAM34148.1 - 3e-06 27.5 0.0 1.4e-05 25.3 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 GAM34148.1 - 3.2e-05 24.3 0.1 0.00032 21.1 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 GAM34148.1 - 0.0055 16.4 0.2 0.044 13.5 0.1 2.2 1 1 1 2 2 2 1 Redoxin TraF PF13728.6 GAM34148.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein OST3_OST6 PF04756.13 GAM34148.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 GAM34148.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 GAM34148.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin tRNA-synt_1 PF00133.22 GAM34149.1 - 7.9e-206 684.9 0.3 2.1e-205 683.6 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAM34149.1 - 6.1e-26 91.2 0.0 5.1e-25 88.2 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAM34149.1 - 1.8e-17 63.2 3.4 1.6e-06 27.2 0.1 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 GAM34149.1 - 0.00026 20.4 0.1 0.0094 15.3 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain DUF4768 PF15989.5 GAM34149.1 - 0.047 13.6 0.7 0.11 12.4 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4768) Fungal_trans PF04082.18 GAM34150.1 - 1.5e-12 47.1 0.0 2.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM34150.1 - 6.7e-08 32.5 9.0 1.2e-07 31.8 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUP214 PF16755.5 GAM34151.1 - 3.3e-05 23.3 0.0 0.00013 21.3 0.0 1.9 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Syntaxin-6_N PF09177.11 GAM34151.1 - 0.002 18.7 0.5 0.0068 16.9 0.5 2.0 1 0 0 1 1 1 1 Syntaxin 6, N-terminal FapA PF03961.13 GAM34151.1 - 0.13 10.8 0.9 0.21 10.2 0.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A YPEB PF14620.6 GAM34151.1 - 0.16 11.3 0.4 0.26 10.6 0.4 1.2 1 0 0 1 1 1 0 YpeB sporulation Golgin_A5 PF09787.9 GAM34151.1 - 0.2 11.1 4.9 0.37 10.2 4.9 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1664 PF07889.12 GAM34151.1 - 1.8 8.7 5.0 11 6.1 2.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Proteasome PF00227.26 GAM34152.1 - 2.6e-45 154.3 0.0 3.2e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 GAM34152.1 - 7.6e-16 57.2 0.1 7.6e-16 57.2 0.1 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Methyltransf_23 PF13489.6 GAM34154.1 - 6.3e-16 58.6 0.0 8.6e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM34154.1 - 3e-11 43.9 0.0 7.4e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM34154.1 - 2.9e-08 34.2 0.0 6.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM34154.1 - 6.6e-08 32.5 0.0 1.1e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM34154.1 - 9e-07 29.6 0.0 3.7e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM34154.1 - 8.6e-05 22.0 0.0 0.00045 19.6 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 GAM34154.1 - 0.0033 16.9 0.1 0.068 12.6 0.0 2.9 3 0 0 3 3 3 1 Putative methyltransferase PrmA PF06325.13 GAM34154.1 - 0.0052 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAM34154.1 - 0.013 15.1 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.9 GAM34154.1 - 0.016 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 GAM34154.1 - 0.041 13.2 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain GidB PF02527.15 GAM34154.1 - 0.22 10.8 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Peptidase_M3 PF01432.20 GAM34155.1 - 1.6e-117 393.6 0.0 2.3e-117 393.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 ApoO PF09769.9 GAM34156.1 - 9.2e-40 135.6 0.1 5.7e-39 133.1 0.1 2.1 2 0 0 2 2 2 1 Apolipoprotein O GRASP55_65 PF04495.14 GAM34157.1 - 1.2e-41 142.3 0.0 2.9e-39 134.5 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 GAM34157.1 - 0.0052 16.6 0.0 0.56 10.1 0.0 2.7 2 0 0 2 2 2 2 PDZ domain Methyltransf_15 PF09445.10 GAM34158.1 - 5.4e-51 172.5 0.0 7.6e-51 172.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 GAM34158.1 - 2.4e-10 40.5 0.0 3.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 GAM34158.1 - 5.1e-07 29.5 0.0 8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 GAM34158.1 - 4.3e-05 22.9 0.0 6.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.18 GAM34158.1 - 0.00012 21.8 0.0 0.00023 20.9 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 GAM34158.1 - 0.00045 20.9 0.0 0.0012 19.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 GAM34158.1 - 0.00049 19.7 0.0 0.00077 19.1 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family Methyltransf_18 PF12847.7 GAM34158.1 - 0.0055 16.6 0.0 0.0094 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM34158.1 - 0.015 15.9 0.0 0.028 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAM34158.1 - 0.043 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_3 PF01596.17 GAM34158.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF3591 PF12157.8 GAM34159.1 - 3.5e-177 589.5 3.2 4.5e-177 589.2 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 GAM34159.1 - 0.0033 17.2 0.8 0.0084 15.9 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle Pkinase PF00069.25 GAM34160.1 - 3e-46 157.9 0.0 1.7e-25 89.9 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAM34160.1 - 3.5e-18 65.8 0.0 2.4e-09 36.9 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 GAM34160.1 - 0.052 13.5 0.3 0.15 12.0 0.2 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family FKBP_C PF00254.28 GAM34161.1 - 3.3e-32 110.7 0.0 1e-31 109.1 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 GAM34161.1 - 1.2e-29 102.9 3.0 1.2e-29 102.9 3.0 2.5 2 2 0 2 2 2 1 Nucleoplasmin-like domain IMS PF00817.20 GAM34162.1 - 6e-38 130.2 0.0 1.4e-37 129.0 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 GAM34162.1 - 8.2e-25 87.0 1.5 2.1e-24 85.7 1.5 1.8 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 GAM34162.1 - 4.1e-16 57.8 13.6 5.2e-10 38.4 2.4 4.2 4 0 0 4 4 4 3 Ubiquitin binding region IMS_C PF11799.8 GAM34162.1 - 2e-13 51.1 0.0 5.4e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 GAM34162.1 - 2.3e-10 40.7 0.0 6.2e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAM34162.1 - 3e-05 24.3 0.0 7.3e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain mCpol PF18182.1 GAM34162.1 - 0.00073 19.9 0.0 0.0029 17.9 0.0 2.0 2 0 0 2 2 2 1 minimal CRISPR polymerase domain PTCB-BRCT PF12738.7 GAM34162.1 - 0.0047 16.9 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.8 GAM34162.1 - 0.0053 17.0 0.3 0.022 15.1 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif DUF1805 PF08827.11 GAM34162.1 - 0.067 13.5 0.0 0.22 11.9 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) NAD_binding_4 PF07993.12 GAM34163.1 - 2.7e-40 138.2 0.0 4.4e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAM34163.1 - 1.5e-27 96.3 0.0 2.7e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAM34163.1 - 6.2e-12 45.5 0.0 4.2e-11 42.8 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAM34163.1 - 1.1e-08 35.3 0.1 2.3e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 GAM34163.1 - 0.00081 18.5 0.1 0.0016 17.5 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM34163.1 - 0.041 13.3 0.1 0.18 11.1 0.1 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 GAM34163.1 - 0.055 13.4 0.1 0.19 11.6 0.1 2.0 1 1 0 1 1 1 0 KR domain Zn_clus PF00172.18 GAM34164.1 - 0.012 15.7 1.7 0.025 14.7 1.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 GAM34165.1 - 1.2e-42 145.6 0.2 2.5e-42 144.6 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM34165.1 - 1.3e-28 99.5 0.0 1.5e-27 96.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1266 PF06889.11 GAM34165.1 - 2.4 8.2 6.5 0.84 9.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Nop14 PF04147.12 GAM34165.1 - 2.4 6.2 28.1 3.9 5.6 19.7 2.3 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 GAM34165.1 - 6.6 4.9 20.9 5.6 5.1 11.7 2.3 2 0 0 2 2 2 0 CDC45-like protein Ndc1_Nup PF09531.10 GAM34165.1 - 8.3 5.0 8.1 16 4.0 8.1 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FtsJ PF01728.19 GAM34166.1 - 1.4e-63 214.2 0.0 5.6e-63 212.2 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase RXT2_N PF08595.11 GAM34166.1 - 0.46 10.5 3.5 0.14 12.2 0.4 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal FAD_binding_1 PF00667.20 GAM34167.1 - 2.5e-65 220.2 0.0 6.3e-65 218.8 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GAM34167.1 - 2.4e-09 37.8 0.0 1.1e-08 35.6 0.0 2.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 GAM34167.1 - 1.9e-07 31.3 0.1 3.6e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 GAM34167.1 - 0.00021 21.5 0.1 0.00072 19.8 0.1 1.9 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 GAM34167.1 - 0.1 12.5 0.2 0.41 10.6 0.1 2.1 2 0 0 2 2 2 0 Transketolase, C-terminal domain MFS_1 PF07690.16 GAM34168.1 - 5.3e-37 127.6 24.4 5.3e-37 127.6 24.4 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM34168.1 - 6.5e-14 51.6 23.3 1.4e-13 50.5 23.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 GAM34168.1 - 1.6e-05 23.6 4.7 2.5e-05 22.9 4.4 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DoxX_3 PF13781.6 GAM34168.1 - 0.022 15.4 0.6 0.022 15.4 0.6 3.0 4 0 0 4 4 4 0 DoxX-like family EMP70 PF02990.16 GAM34168.1 - 2.3 6.8 6.1 8.3 4.9 2.1 2.3 2 0 0 2 2 2 0 Endomembrane protein 70 Fungal_trans PF04082.18 GAM34169.1 - 2.7e-11 43.0 1.3 5.1e-11 42.1 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 GAM34169.1 - 7.9e-09 35.5 4.5 2.6e-08 33.9 1.8 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 GAM34169.1 - 6.2e-06 26.4 17.6 0.00047 20.5 0.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.18 GAM34169.1 - 7.4e-06 26.0 11.9 2.3e-05 24.4 11.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 GAM34169.1 - 0.0055 17.4 14.5 0.027 15.3 0.4 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAM34169.1 - 0.035 14.1 4.6 0.96 9.5 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 GAM34169.1 - 0.91 10.0 9.0 0.7 10.4 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type adh_short_C2 PF13561.6 GAM34170.1 - 6.5e-44 150.2 2.0 6.5e-43 147.0 2.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM34170.1 - 1.5e-37 129.0 0.8 6.4e-37 126.9 0.8 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM34170.1 - 5.7e-10 39.4 2.4 2.6e-09 37.2 1.9 2.0 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 GAM34170.1 - 0.00031 20.3 0.1 0.0046 16.5 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 GAM34170.1 - 0.0068 16.8 0.1 0.014 15.8 0.1 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAM34170.1 - 0.011 16.0 0.1 0.02 15.2 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Cupin_2 PF07883.11 GAM34171.1 - 6.6e-09 35.4 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 GAM34171.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 GAM34171.1 - 0.05 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) RPN1_C PF18051.1 GAM34171.1 - 0.068 13.2 0.0 5.3 7.2 0.0 2.5 2 0 0 2 2 2 0 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal Histidinol_dh PF00815.20 GAM34172.1 - 5.1e-137 457.2 0.1 6e-137 457.0 0.1 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase AAA_24 PF13479.6 GAM34172.1 - 0.0051 16.6 0.2 0.083 12.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain FAD_binding_3 PF01494.19 GAM34173.1 - 3.1e-18 66.1 0.0 5.8e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.11 GAM34173.1 - 6.5e-08 32.4 0.1 1e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.14 GAM34173.1 - 1.6e-05 24.3 2.5 0.013 14.7 0.7 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM34173.1 - 0.00052 20.2 0.5 0.0015 18.7 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM34173.1 - 0.00092 18.4 1.9 0.0015 17.7 1.9 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 GAM34173.1 - 0.0052 16.1 0.4 0.38 10.0 0.2 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAM34173.1 - 0.061 12.4 0.2 0.1 11.6 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAM34173.1 - 0.069 12.5 0.6 0.15 11.4 0.6 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM34173.1 - 0.074 13.6 1.8 1.4 9.5 0.2 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM34173.1 - 0.27 10.8 6.5 3.4 7.1 3.0 2.3 1 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM34173.1 - 0.41 9.3 1.9 2.3 6.8 0.3 2.3 2 0 0 2 2 2 0 HI0933-like protein Aldedh PF00171.22 GAM34174.1 - 8.8e-128 426.7 0.3 1.1e-127 426.4 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Mur_ligase PF01225.25 GAM34174.1 - 0.11 12.9 0.1 0.74 10.2 0.0 2.3 1 1 1 2 2 2 0 Mur ligase family, catalytic domain DUF1611_N PF17396.2 GAM34174.1 - 0.13 12.5 0.0 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain HIM1 PF08732.10 GAM34175.1 - 4.1e-05 23.2 0.0 5.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 HIM1 NAD_binding_10 PF13460.6 GAM34175.1 - 0.0006 19.8 0.0 0.0015 18.5 0.0 1.6 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 GAM34175.1 - 0.0012 18.4 0.0 0.0025 17.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 GAM34175.1 - 0.019 15.4 0.1 0.11 13.0 0.0 2.0 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 GAM34175.1 - 0.036 13.6 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family SHE3 PF17078.5 GAM34177.1 - 0.00065 19.5 0.2 0.00078 19.2 0.2 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Proteasome PF00227.26 GAM34178.1 - 2.7e-60 203.1 0.1 3.2e-60 202.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAM34178.1 - 2.6e-13 49.4 0.1 8.6e-13 47.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.14 GAM34178.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF5624 PF18538.1 GAM34178.1 - 0.024 14.8 0.5 0.054 13.6 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) FF PF01846.19 GAM34179.1 - 1.8e-09 37.6 16.3 1.1e-08 35.2 0.1 3.7 4 0 0 4 4 4 2 FF domain WW PF00397.26 GAM34179.1 - 5.9e-09 35.9 2.5 5.9e-09 35.9 2.5 3.4 4 0 0 4 4 4 2 WW domain SPOC PF07744.13 GAM34181.1 - 3.7e-24 85.3 0.0 8.8e-24 84.1 0.0 1.7 2 0 0 2 2 2 1 SPOC domain TFIIS_M PF07500.14 GAM34181.1 - 2.3e-23 82.8 0.0 2.3e-23 82.8 0.0 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 GAM34181.1 - 9.7e-11 41.4 12.1 1.7e-10 40.6 12.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAM34181.1 - 0.073 12.6 4.1 0.13 11.8 4.1 1.4 1 0 0 1 1 1 0 PHD-finger PHD_3 PF13922.6 GAM34181.1 - 0.33 11.4 7.4 0.057 13.8 0.7 2.9 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx LUC7 PF03194.15 GAM34182.1 - 9.8e-74 248.2 1.3 1.2e-73 247.9 1.3 1.0 1 0 0 1 1 1 1 LUC7 N_terminus TelA PF05816.11 GAM34182.1 - 0.023 13.8 0.5 0.038 13.1 0.5 1.3 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) MCPsignal PF00015.21 GAM34182.1 - 0.047 13.5 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Arfaptin PF06456.13 GAM34182.1 - 0.047 13.2 0.6 0.081 12.5 0.7 1.4 1 1 0 1 1 1 0 Arfaptin-like domain T4SS PF07996.11 GAM34182.1 - 0.048 14.1 0.3 0.097 13.1 0.3 1.5 1 0 0 1 1 1 0 Type IV secretion system proteins DUF2130 PF09903.9 GAM34182.1 - 0.068 12.4 0.6 0.13 11.6 0.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Glutaredoxin2_C PF04399.13 GAM34182.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain PIN_8 PF18476.1 GAM34182.1 - 0.11 12.3 0.2 0.26 11.1 0.1 1.6 2 0 0 2 2 2 0 PIN like domain DegS PF05384.11 GAM34182.1 - 0.23 10.9 1.6 0.62 9.5 0.5 2.1 1 1 1 2 2 2 0 Sensor protein DegS Occludin_ELL PF07303.13 GAM34182.1 - 0.33 11.7 2.8 1.1 10.1 0.4 2.5 3 0 0 3 3 3 0 Occludin homology domain XhlA PF10779.9 GAM34182.1 - 0.93 9.7 3.8 0.98 9.7 1.2 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Gpi16 PF04113.14 GAM34183.1 - 3.4e-240 798.3 0.0 4.3e-240 798.0 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Spt20 PF12090.8 GAM34185.1 - 0.032 13.9 8.1 0.064 12.9 8.1 1.5 1 0 0 1 1 1 0 Spt20 family DUF3445 PF11927.8 GAM34186.1 - 2.1e-75 253.2 0.0 2.6e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) TauD PF02668.16 GAM34187.1 - 1.9e-32 113.1 0.1 4e-32 112.1 0.1 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family dCMP_cyt_deam_1 PF00383.23 GAM34188.1 - 0.00099 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Hydrolase_4 PF12146.8 GAM34189.1 - 2.4e-22 79.4 0.0 3e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM34189.1 - 1.8e-17 63.8 0.0 4.6e-15 56.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM34189.1 - 3.3e-15 57.3 0.1 4.2e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 GAM34189.1 - 6.6e-07 29.2 0.0 7.8e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 GAM34189.1 - 6.7e-06 26.1 0.1 0.023 14.5 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 GAM34189.1 - 1.3e-05 25.1 0.2 6.9e-05 22.8 0.2 2.1 1 1 1 2 2 2 1 Serine hydrolase DUF1749 PF08538.10 GAM34189.1 - 2.2e-05 23.7 0.0 3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.7 GAM34189.1 - 0.00011 22.0 0.0 0.00047 20.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 GAM34189.1 - 0.00065 19.4 0.1 0.0024 17.6 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.14 GAM34189.1 - 0.0013 17.5 0.0 0.0019 16.9 0.0 1.3 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 GAM34189.1 - 0.0041 17.3 0.0 0.053 13.6 0.0 2.1 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 GAM34189.1 - 0.0066 16.2 0.0 0.02 14.6 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_3 PF07859.13 GAM34189.1 - 0.012 15.5 0.1 0.017 15.0 0.1 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 GAM34189.1 - 0.035 13.7 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_4 PF08386.10 GAM34189.1 - 0.039 14.1 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DUF1057 PF06342.12 GAM34189.1 - 0.075 12.1 0.0 0.21 10.6 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase2 PF12740.7 GAM34189.1 - 0.11 11.4 0.0 0.22 10.4 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme FSH1 PF03959.13 GAM34189.1 - 0.11 12.1 0.0 2 8.0 0.0 2.6 2 1 0 2 2 2 0 Serine hydrolase (FSH1) DUF676 PF05057.14 GAM34189.1 - 0.15 11.6 0.2 0.39 10.2 0.2 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 GAM34189.1 - 0.24 11.2 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase TauD PF02668.16 GAM34190.1 - 5.2e-34 118.3 0.2 7.3e-34 117.8 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Transp_cyt_pur PF02133.15 GAM34191.1 - 6.9e-81 272.3 28.3 8.3e-81 272.0 28.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans_2 PF11951.8 GAM34192.1 - 1.1e-22 80.4 0.6 1.9e-22 79.6 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM34192.1 - 5.6e-12 45.6 24.4 1.8e-07 31.1 12.6 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 GAM34192.1 - 0.00015 20.4 0.0 0.00024 19.7 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B Fungal_trans PF04082.18 GAM34192.1 - 0.0045 16.0 0.6 0.0095 15.0 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMO-like PF00743.19 GAM34193.1 - 9.7e-17 60.6 1.6 1.2e-14 53.6 1.6 2.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAM34193.1 - 4.1e-12 46.0 0.4 1.5e-06 27.7 0.7 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM34193.1 - 2.7e-10 40.0 0.2 5.7e-08 32.3 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM34193.1 - 5.7e-08 32.3 2.9 2e-06 27.2 0.2 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 GAM34193.1 - 0.00012 22.5 0.2 0.5 11.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM34193.1 - 0.0024 18.1 0.1 0.0064 16.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAM34193.1 - 0.0027 17.0 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 GAM34193.1 - 0.0058 16.0 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAM34193.1 - 0.025 14.7 0.0 0.098 12.7 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 GAM34193.1 - 0.038 13.6 2.2 0.12 11.9 0.9 2.3 1 1 1 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM34193.1 - 0.066 11.9 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 GAM34193.1 - 0.13 12.5 0.2 11 6.3 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.6 GAM34193.1 - 0.14 12.2 0.2 3.7 7.5 0.0 2.8 4 0 0 4 4 4 0 FAD-NAD(P)-binding VHS PF00790.19 GAM34194.1 - 2.2e-24 85.9 0.0 4.6e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 GAM34194.1 - 2.6e-05 24.5 0.2 5.8e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 GAT domain ENTH PF01417.20 GAM34194.1 - 0.00048 20.2 0.0 0.0017 18.4 0.0 1.8 2 0 0 2 2 2 1 ENTH domain Hrs_helical PF12210.8 GAM34194.1 - 0.12 13.0 0.2 0.24 12.0 0.2 1.4 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Inositol_P PF00459.25 GAM34195.1 - 6e-52 176.8 1.1 1.3e-51 175.8 1.1 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.23 GAM34196.1 - 1.5e-25 89.6 0.0 8.4e-13 48.8 0.0 2.8 2 1 0 2 2 2 2 Ribosomal protein L6 Tht1 PF04163.12 GAM34197.1 - 1.3e-06 27.5 7.8 4.3e-06 25.8 0.2 2.3 1 1 1 2 2 2 1 Tht1-like nuclear fusion protein Spermine_synth PF01564.17 GAM34197.1 - 0.063 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase domain RIX1 PF08167.12 GAM34197.1 - 0.53 10.0 6.6 0.59 9.9 0.7 2.8 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis DUF2018 PF09442.10 GAM34197.1 - 0.53 11.3 0.1 0.53 11.3 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2018) DUF2407_C PF13373.6 GAM34197.1 - 0.81 9.9 5.4 0.29 11.3 0.2 2.6 3 0 0 3 3 3 0 DUF2407 C-terminal domain V_ATPase_I PF01496.19 GAM34197.1 - 1.8 6.4 10.1 0.12 10.3 2.3 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family IL3 PF02059.15 GAM34197.1 - 6.8 6.8 8.8 3.8 7.6 1.5 3.2 2 1 0 3 3 3 0 Interleukin-3 SesA PF17107.5 GAM34197.1 - 8.6 6.6 10.3 13 6.0 0.3 3.6 2 1 1 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases COesterase PF00135.28 GAM34198.1 - 2.5e-80 270.8 0.0 4.5e-79 266.7 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM34198.1 - 3.7e-05 23.7 0.4 9.8e-05 22.3 0.4 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM34198.1 - 0.0029 17.1 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Flavoprotein PF02441.19 GAM34199.1 - 6.2e-14 52.1 0.0 1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.6 GAM34199.1 - 4.5e-05 23.9 0.1 1.4 9.6 0.0 4.2 4 1 0 4 4 4 2 Ankyrin repeats (many copies) DUF1391 PF07151.12 GAM34199.1 - 0.073 12.9 0.4 0.29 11.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1391) MFS_1 PF07690.16 GAM34200.1 - 1.2e-42 146.1 44.9 1.2e-42 146.1 44.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM34200.1 - 8.3e-15 54.6 15.8 8.3e-15 54.6 15.8 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter APG12 PF04110.13 GAM34201.1 - 1e-26 93.1 0.0 1.4e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 GAM34201.1 - 0.0011 19.1 0.0 0.0015 18.7 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like UQ_con PF00179.26 GAM34202.1 - 2.2e-34 118.1 0.1 2.7e-34 117.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LAMTOR PF15454.6 GAM34203.1 - 4.6e-16 59.2 0.2 8.7e-16 58.3 0.2 1.5 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF2011 PF09428.10 GAM34204.1 - 1.6e-28 98.8 0.1 1.6e-28 98.8 0.1 2.2 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF2011) EMC3_TMCO1 PF01956.16 GAM34204.1 - 7 6.4 6.9 17 5.1 6.9 1.7 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Pantoate_transf PF02548.15 GAM34205.1 - 2.5e-107 358.1 1.5 3.1e-107 357.8 1.5 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 GAM34205.1 - 8.6e-08 31.9 1.6 1.9e-07 30.8 1.6 1.7 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PEP_mutase PF13714.6 GAM34206.1 - 9.5e-61 205.3 0.2 1.5e-60 204.7 0.2 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 GAM34206.1 - 3e-05 22.7 0.3 4.5e-05 22.1 0.3 1.2 1 0 0 1 1 1 1 Isocitrate lyase family PucR PF07905.11 GAM34206.1 - 0.068 13.4 0.1 1.4 9.2 0.0 2.4 1 1 1 2 2 2 0 Purine catabolism regulatory protein-like family PA PF02225.22 GAM34206.1 - 0.083 12.9 2.8 2.6 8.1 0.0 2.9 2 1 1 3 3 3 0 PA domain Isochorismatase PF00857.20 GAM34207.1 - 6.9e-14 52.4 0.0 1.3e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.16 GAM34208.1 - 3.9e-33 114.8 26.2 3.9e-33 114.8 26.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily 7TM_GPCR_Srab PF10292.9 GAM34208.1 - 0.078 11.9 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Ribonuc_L-PSP PF01042.21 GAM34209.1 - 7.6e-20 71.1 0.1 9.4e-20 70.8 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP TAL_effector PF03377.13 GAM34209.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 TAL effector repeat Fungal_trans PF04082.18 GAM34210.1 - 2.1e-28 99.1 0.1 3.3e-28 98.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.21 GAM34211.1 - 2.7e-66 224.4 0.0 1.9e-43 149.1 0.0 2.3 2 0 0 2 2 2 2 Amidase adh_short_C2 PF13561.6 GAM34212.1 - 2.4e-60 204.0 0.5 2.7e-60 203.8 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM34212.1 - 1.5e-53 181.1 2.1 2.3e-53 180.6 1.5 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAM34212.1 - 1.3e-13 51.3 0.5 1.7e-13 50.9 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM34212.1 - 2.6e-06 27.1 1.5 5.2e-06 26.1 1.5 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM34212.1 - 0.00058 19.4 0.0 0.00075 19.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAM34212.1 - 0.0045 16.1 0.4 0.013 14.6 0.2 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 GAM34212.1 - 0.02 14.3 0.3 0.03 13.7 0.3 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 GAM34212.1 - 0.04 13.2 1.7 0.082 12.2 1.4 1.8 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 GAM34212.1 - 0.06 12.9 1.2 0.11 12.0 1.0 1.6 1 1 0 1 1 1 0 NmrA-like family Amino_oxidase PF01593.24 GAM34213.1 - 1.7e-38 133.1 0.0 2e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Transketolase_N PF00456.21 GAM34214.1 - 1.8e-107 359.2 0.0 2.4e-107 358.7 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAM34214.1 - 4.9e-32 111.0 0.0 9.5e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAM34214.1 - 3.1e-10 40.0 0.0 6.8e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAM34214.1 - 7.8e-07 28.6 0.0 2e-05 23.9 0.0 2.9 2 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 GAM34214.1 - 0.00014 21.6 0.1 0.00047 20.0 0.1 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 GAM34214.1 - 0.00055 19.0 0.0 0.0014 17.7 0.0 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component TPP_enzyme_N PF02776.18 GAM34214.1 - 0.051 13.2 0.0 0.37 10.4 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain FAD_binding_4 PF01565.23 GAM34215.1 - 1.6e-15 57.1 0.2 2.7e-15 56.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain T3SS_needle_E PF08988.10 GAM34215.1 - 0.047 13.8 1.6 0.12 12.6 1.6 1.6 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle DUF3435 PF11917.8 GAM34215.1 - 0.15 11.0 4.0 0.23 10.4 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) T5orf172 PF10544.9 GAM34216.1 - 4.4e-20 72.2 0.8 1.7e-19 70.3 0.8 2.1 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 GAM34216.1 - 3.1e-10 40.6 2.0 8.7e-10 39.1 2.0 1.8 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Papo_T_antigen PF02380.15 GAM34216.1 - 0.73 10.0 3.2 1.6 8.9 0.5 2.3 2 0 0 2 2 2 0 T-antigen specific domain ADH_zinc_N_2 PF13602.6 GAM34217.1 - 3e-11 44.5 0.0 7.3e-11 43.3 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAM34217.1 - 1.2e-10 41.5 0.1 4.9e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM34217.1 - 4e-08 33.1 0.0 7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_3 PF07859.13 GAM34218.1 - 1e-36 126.8 0.2 1.7e-36 126.0 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAM34218.1 - 0.0002 20.4 1.4 0.00068 18.6 0.1 2.4 3 1 0 3 3 3 1 Carboxylesterase family Chlorophyllase PF07224.11 GAM34218.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Pyr_redox_2 PF07992.14 GAM34220.1 - 1.4e-35 123.0 0.0 1.8e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM34220.1 - 4.9e-11 43.0 0.1 2.4e-09 37.6 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM34220.1 - 3.8e-08 33.0 0.1 3.8e-05 23.1 0.1 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM34220.1 - 7.7e-08 31.8 0.7 0.0032 16.6 0.0 3.2 2 1 1 3 3 3 3 Lycopene cyclase protein NAD_binding_9 PF13454.6 GAM34220.1 - 3.7e-05 23.7 0.9 3.1 7.8 0.0 4.1 2 2 1 4 4 4 2 FAD-NAD(P)-binding KR PF08659.10 GAM34220.1 - 0.0014 18.5 0.3 0.0062 16.5 0.1 2.0 2 0 0 2 2 2 1 KR domain Thi4 PF01946.17 GAM34220.1 - 0.004 16.4 0.3 0.4 9.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 GAM34220.1 - 0.0083 15.5 0.6 0.094 12.0 0.1 2.0 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 GAM34220.1 - 0.011 14.9 2.7 2.6 7.1 0.1 3.3 3 1 1 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 GAM34220.1 - 0.012 15.9 0.1 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.19 GAM34220.1 - 0.023 14.0 0.2 0.97 8.6 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 GAM34220.1 - 0.077 12.6 1.2 16 4.9 0.0 3.2 3 1 1 4 4 4 0 FAD dependent oxidoreductase ThiF PF00899.21 GAM34220.1 - 0.19 11.0 0.4 0.37 10.1 0.1 1.6 2 0 0 2 2 2 0 ThiF family GIDA PF01134.22 GAM34220.1 - 0.2 10.7 3.5 2.7 7.0 0.2 2.8 2 1 2 4 4 4 0 Glucose inhibited division protein A DJ-1_PfpI PF01965.24 GAM34221.1 - 6.5e-15 55.3 0.0 1.3e-14 54.4 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 GAM34221.1 - 0.00019 21.2 0.0 0.0011 18.7 0.0 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like Glyco_hydro_18 PF00704.28 GAM34222.1 - 3.6e-21 76.2 2.2 1.5e-20 74.1 2.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Methyltransf_2 PF00891.18 GAM34223.1 - 1.5e-22 79.9 0.0 2.5e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 GAM34223.1 - 0.0088 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FAD_binding_4 PF01565.23 GAM34224.1 - 2.9e-16 59.5 1.1 7.7e-16 58.1 1.1 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM34224.1 - 1.9e-11 43.9 0.2 9.1e-11 41.7 0.2 2.2 2 0 0 2 2 2 1 Berberine and berberine like DUF1324 PF07038.11 GAM34224.1 - 0.082 13.2 0.2 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) NAGLU PF05089.12 GAM34225.1 - 2.1e-128 428.0 8.0 3.5e-128 427.3 8.0 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 GAM34225.1 - 2.6e-70 237.0 3.9 5.5e-70 235.9 3.9 1.5 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 GAM34225.1 - 4.3e-20 71.3 0.0 1.1e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Fungal_trans PF04082.18 GAM34225.1 - 2.1e-12 46.6 0.6 4.5e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain NmrA PF05368.13 GAM34226.1 - 1.8e-22 80.1 0.0 2.3e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM34226.1 - 3.5e-07 30.3 0.0 4.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAM34226.1 - 2.6e-05 24.5 0.0 5.8e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 GAM34226.1 - 0.00031 21.2 0.1 0.00062 20.2 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 GAM34226.1 - 0.033 13.4 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.19 GAM34226.1 - 0.062 12.3 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 GAM34226.1 - 0.089 12.9 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF3533 PF12051.8 GAM34227.1 - 4e-115 384.8 6.8 4.5e-115 384.6 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Sugar_tr PF00083.24 GAM34228.1 - 7.8e-82 275.5 10.4 9.5e-82 275.2 10.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM34228.1 - 3.4e-32 111.7 37.5 2.3e-20 72.8 11.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAM34228.1 - 7.8e-08 31.1 0.8 1.2e-05 23.9 0.0 2.8 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 GAM34228.1 - 0.02 13.8 12.7 0.26 10.1 0.3 3.6 1 1 1 2 2 2 0 MFS_1 like family GPI2 PF06432.11 GAM34228.1 - 5.8 6.3 7.3 4.5 6.6 0.2 2.7 2 1 1 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF2207 PF09972.9 GAM34228.1 - 7.1 5.3 5.5 4.6 5.9 0.1 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Dfp1_Him1_M PF08630.10 GAM34229.1 - 4.7e-42 143.2 2.1 9.1e-42 142.3 0.0 2.5 3 0 0 3 3 3 1 Dfp1/Him1, central region zf-DBF PF07535.12 GAM34229.1 - 2.6e-20 72.2 0.1 4.4e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 DBF zinc finger Pet100 PF09803.9 GAM34229.1 - 4.7 7.8 5.4 5.3 7.6 0.9 3.2 3 0 0 3 3 3 0 Pet100 DUF2681 PF10883.8 GAM34229.1 - 4.7 7.7 7.0 12 6.4 7.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Peptidase_M24 PF00557.24 GAM34230.1 - 4.5e-48 163.7 0.0 7.3e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 GAM34230.1 - 7.1e-36 122.6 0.0 1.5e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Alpha-2-MRAP_C PF06401.11 GAM34231.1 - 0.029 14.3 0.7 0.048 13.6 0.7 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain RRM_1 PF00076.22 GAM34231.1 - 0.081 12.8 0.1 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyridox_ox_2 PF12900.7 GAM34232.1 - 3.3e-41 140.6 0.0 5e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SIR2 PF02146.17 GAM34233.1 - 6e-40 137.0 0.0 1.9e-39 135.4 0.0 1.7 1 1 0 1 1 1 1 Sir2 family SNF2_N PF00176.23 GAM34234.1 - 1.5e-68 231.1 2.8 2.4e-66 223.8 0.3 3.5 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM34234.1 - 9.2e-16 58.2 0.0 4e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM34234.1 - 1.1e-08 35.2 0.6 3.9e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 GAM34234.1 - 0.0026 16.7 0.1 0.0082 15.1 0.1 1.7 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 SLX9 PF15341.6 GAM34234.1 - 3 8.3 13.3 0.85 10.0 2.8 2.9 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Yip1 PF04893.17 GAM34235.1 - 0.021 14.5 0.1 0.029 14.1 0.1 1.1 1 0 0 1 1 1 0 Yip1 domain Cytochrom_B558a PF05038.13 GAM34235.1 - 0.025 14.1 0.1 0.042 13.4 0.1 1.3 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Shisa PF13908.6 GAM34235.1 - 0.025 14.8 0.2 0.025 14.8 0.2 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator COX14 PF14880.6 GAM34235.1 - 0.032 14.0 0.0 0.032 14.0 0.0 1.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly TMEM51 PF15345.6 GAM34235.1 - 0.055 13.3 5.7 0.12 12.2 5.6 1.8 1 1 0 1 1 1 0 Transmembrane protein 51 Nuc_sug_transp PF04142.15 GAM34235.1 - 0.074 12.2 0.2 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 Nucleotide-sugar transporter S1FA PF04689.13 GAM34235.1 - 0.096 12.8 0.4 0.096 12.8 0.4 1.7 2 0 0 2 2 2 0 DNA binding protein S1FA TMEM154 PF15102.6 GAM34235.1 - 0.1 12.5 0.2 0.1 12.5 0.2 2.4 2 1 0 2 2 2 0 TMEM154 protein family DHHC PF01529.20 GAM34235.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF898 PF05987.13 GAM34235.1 - 0.14 11.2 0.2 0.2 10.7 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Miga PF10265.9 GAM34235.1 - 0.26 10.2 5.0 0.39 9.6 5.0 1.2 1 0 0 1 1 1 0 Mitoguardin SIT PF15330.6 GAM34235.1 - 0.34 11.4 1.4 0.61 10.5 0.3 2.1 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT HemY_N PF07219.13 GAM34235.1 - 0.37 11.0 12.6 1.9e+02 2.3 10.5 2.6 2 1 0 2 2 2 0 HemY protein N-terminus DUF3302 PF11742.8 GAM34235.1 - 1.1 9.4 6.8 0.09 12.9 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3302) EphA2_TM PF14575.6 GAM34235.1 - 7.6 7.5 7.5 4.2e+02 1.9 0.0 3.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PHY PF00360.20 GAM34236.1 - 3.4e-31 108.0 0.0 7.6e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 GAM34236.1 - 1.9e-18 67.0 0.1 4.5e-18 65.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM34236.1 - 1.5e-16 60.5 0.0 4.6e-16 59.0 0.0 1.9 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 GAM34236.1 - 7.2e-12 46.1 0.0 2e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 GAM34236.1 - 1.4e-11 44.3 0.6 4.1e-11 42.8 0.6 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 GAM34236.1 - 6.4e-10 39.7 0.0 2.1e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 GAM34236.1 - 0.0047 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 GAM34236.1 - 0.024 14.5 0.0 0.092 12.7 0.0 1.9 2 0 0 2 2 2 0 GHKL domain HATPase_c_2 PF13581.6 GAM34236.1 - 0.062 13.3 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Cellulase PF00150.18 GAM34237.1 - 1.4e-08 34.5 0.7 1.4e-08 34.5 0.7 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) COX6C PF02937.15 GAM34237.1 - 0.31 11.2 0.6 28 4.9 0.2 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc CAP59_mtransfer PF11735.8 GAM34238.1 - 1.2e-69 234.7 0.0 1.5e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Herpes_US9 PF06072.11 GAM34238.1 - 0.4 10.6 2.2 0.83 9.6 2.2 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 p450 PF00067.22 GAM34239.1 - 1.5e-47 162.5 0.0 2e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PRP4 PF08799.11 GAM34239.1 - 0.00037 20.0 0.2 0.00074 19.0 0.2 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Candida_ALS_N PF11766.8 GAM34239.1 - 0.091 12.0 0.3 0.15 11.3 0.3 1.2 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding Pkinase PF00069.25 GAM34240.1 - 1.1e-61 208.5 0.0 1.5e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM34240.1 - 1.5e-32 112.9 0.0 2.1e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM34240.1 - 2.4e-06 27.1 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM34240.1 - 0.00095 18.6 0.1 0.0017 17.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM34240.1 - 0.0015 18.5 1.2 0.0033 17.4 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM34240.1 - 0.013 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 GAM34240.1 - 0.017 13.9 0.0 0.034 12.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Endonuc_Holl PF10107.9 GAM34240.1 - 0.11 12.3 0.4 0.99 9.2 0.0 2.1 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase MFS_1 PF07690.16 GAM34241.1 - 3e-14 52.7 47.6 3e-14 52.7 47.6 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM34241.1 - 0.0004 19.4 37.9 0.0011 17.9 15.2 2.5 1 1 0 2 2 2 2 Sugar (and other) transporter Pollen_allerg_1 PF01357.21 GAM34242.1 - 0.00027 20.9 7.9 0.0018 18.3 0.8 2.6 3 0 0 3 3 3 2 Pollen allergen Cerato-platanin PF07249.12 GAM34242.1 - 0.00073 19.7 4.8 0.0013 18.9 3.9 2.0 1 1 0 1 1 1 1 Cerato-platanin DPBB_1 PF03330.18 GAM34242.1 - 0.0091 16.3 1.9 0.086 13.1 0.1 3.1 3 1 0 3 3 3 1 Lytic transglycolase Glyco_hydro_11 PF00457.17 GAM34244.1 - 2.2e-63 213.1 9.6 2.7e-63 212.8 9.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Glyco_hydro_62 PF03664.13 GAM34245.1 - 1.6e-150 499.9 14.1 1.9e-150 499.7 14.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Esterase PF00756.20 GAM34246.1 - 2.5e-13 50.2 0.0 3.8e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 GAM34246.1 - 1.7e-06 27.7 0.0 3.6e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 GAM34246.1 - 1.3e-05 24.7 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM34246.1 - 0.0017 19.0 0.0 0.0026 18.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 GAM34246.1 - 0.0085 14.9 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 GAM34246.1 - 0.036 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 GAM34246.1 - 0.2 11.3 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase GSH_synth_ATP PF03917.17 GAM34248.1 - 2.2e-104 349.2 0.0 2.5e-104 349.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 GAM34248.1 - 3.8e-25 88.3 0.0 7.1e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Mistic PF11458.8 GAM34248.1 - 0.048 13.6 0.0 1.2 9.2 0.0 2.8 3 0 0 3 3 3 0 Membrane-integrating protein Mistic Med13_C PF06333.12 GAM34249.1 - 5.2e-88 295.5 1.0 5.2e-88 295.5 1.0 3.0 3 1 1 4 4 4 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 GAM34249.1 - 7.4e-72 242.4 0.1 1.2e-71 241.6 0.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 GAM34249.1 - 1.3e-31 110.2 0.1 2.1e-19 70.3 0.2 4.2 2 2 1 3 3 3 2 MID domain of medPIWI NUC153 PF08159.12 GAM34250.1 - 8.7e-13 47.8 1.5 1.9e-12 46.8 1.5 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 GAM34250.1 - 4.2e-05 24.2 0.0 41 5.3 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM34250.1 - 0.11 12.8 0.0 1 9.7 0.0 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ATG13 PF10033.9 GAM34251.1 - 1.4e-70 237.7 0.0 2.8e-70 236.7 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 13 RCC1 PF00415.18 GAM34252.1 - 1.7e-22 79.8 0.1 1.1e-06 29.2 0.0 5.9 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 GAM34252.1 - 3.9e-17 62.5 0.1 3.6e-11 43.3 0.0 3.2 3 0 0 3 3 3 2 BTB/POZ domain RCC1_2 PF13540.6 GAM34252.1 - 1e-10 41.1 2.2 1.7e-08 34.0 0.1 3.9 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 GAM34252.1 - 1.4e-08 35.1 0.0 4e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM34252.1 - 5.1e-06 26.4 0.1 0.33 11.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 GAM34252.1 - 9.8e-05 22.9 0.0 0.00026 21.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAM34252.1 - 0.059 13.8 0.1 2.2 8.9 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat VHS PF00790.19 GAM34254.1 - 2.7e-41 140.7 2.2 1.4e-40 138.4 0.1 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 GAM34254.1 - 3e-16 59.3 1.3 4.9e-16 58.6 1.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 GAM34254.1 - 6.9e-06 25.6 19.2 0.0018 18.0 3.5 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 GAM34254.1 - 8.6e-06 26.0 0.2 6.2e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 GAT domain Npa1 PF11707.8 GAM34254.1 - 0.032 13.6 0.2 0.055 12.8 0.2 1.3 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal OrfB_Zn_ribbon PF07282.11 GAM34254.1 - 0.13 12.2 2.1 1.7 8.6 3.9 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain FYVE_2 PF02318.16 GAM34254.1 - 0.15 12.3 0.5 0.33 11.2 0.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 GAM34254.1 - 0.37 10.8 2.5 0.74 9.9 2.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon Ank_2 PF12796.7 GAM34255.1 - 2.6e-20 72.8 5.0 1.4e-05 25.6 0.2 5.6 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM34255.1 - 3.2e-14 51.6 8.5 0.13 12.9 0.0 9.6 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 GAM34255.1 - 3.8e-13 49.4 8.6 0.012 15.9 0.2 8.4 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM34255.1 - 9.7e-13 48.4 11.1 0.19 12.4 0.1 7.6 4 4 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 GAM34255.1 - 1.3e-11 44.4 8.8 1.8 9.2 0.0 8.8 9 0 0 9 9 9 3 Ankyrin repeat DUF1871 PF08958.10 GAM34255.1 - 0.024 14.9 0.1 1.9 8.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1871) UCH PF00443.29 GAM34256.1 - 2.1e-54 184.7 0.1 3.8e-54 183.9 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM34256.1 - 3.9e-15 56.3 0.1 2.8e-12 46.9 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 GAM34256.1 - 0.00012 22.3 0.4 0.00029 21.0 0.0 1.9 2 0 0 2 2 2 1 USP8 dimerisation domain Rhodanese PF00581.20 GAM34256.1 - 0.00017 22.1 0.0 0.00036 21.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Cyt-b5 PF00173.28 GAM34257.1 - 1.3e-21 76.5 0.2 1.7e-21 76.2 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mito_carr PF00153.27 GAM34258.1 - 1.4e-54 182.0 5.5 9.6e-20 70.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 GAM34258.1 - 0.14 12.3 2.8 12 6.1 0.1 3.0 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif KH_1 PF00013.29 GAM34259.1 - 4.6e-89 292.2 35.2 8.1e-13 48.0 0.4 15.5 15 2 1 16 16 16 8 KH domain SLS PF14611.6 GAM34259.1 - 3.5e-14 53.2 8.1 0.027 14.3 0.1 7.4 4 3 3 7 7 7 5 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 GAM34259.1 - 3.6e-09 36.3 21.7 0.019 14.8 0.1 6.8 5 1 1 6 6 6 3 KH domain DUF4974 PF16344.5 GAM34259.1 - 0.044 13.8 0.0 18 5.4 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4974) LeuA_dimer PF08502.10 GAM34259.1 - 0.077 12.9 0.6 0.61 10.0 0.0 2.6 2 0 0 2 2 2 0 LeuA allosteric (dimerisation) domain DUF1735 PF08522.10 GAM34259.1 - 0.13 12.9 0.0 0.5 11.0 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) Acylphosphatase PF00708.18 GAM34259.1 - 0.79 10.2 3.0 4.3 7.8 0.3 3.7 3 0 0 3 3 3 0 Acylphosphatase KH_5 PF13184.6 GAM34259.1 - 3.2 7.9 10.7 27 4.9 0.0 5.6 6 1 0 6 6 6 0 NusA-like KH domain NACHT_N PF17100.5 GAM34260.1 - 8.9e-41 140.2 0.9 8.9e-41 140.2 0.9 2.4 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 GAM34260.1 - 4.7e-22 78.4 0.1 3.9e-07 30.6 0.0 5.0 3 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 GAM34260.1 - 4.8e-20 71.1 1.5 0.00018 21.8 0.1 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 GAM34260.1 - 7.8e-20 68.9 0.9 7.9e-06 25.8 0.2 6.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 GAM34260.1 - 9.2e-18 64.4 0.1 9.7e-07 29.2 0.1 5.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM34260.1 - 2.8e-16 59.3 0.3 0.0011 19.2 0.0 5.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) NACHT PF05729.12 GAM34260.1 - 2.9e-06 27.3 0.0 8.7e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Fringe PF02434.16 GAM34260.1 - 3.3e-05 23.5 0.0 7.9e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Fringe-like KAP_NTPase PF07693.14 GAM34260.1 - 0.022 14.0 1.5 6.4 5.9 0.2 3.6 3 0 0 3 3 3 0 KAP family P-loop domain LINES_C PF14695.6 GAM34260.1 - 0.13 11.7 0.1 0.49 9.9 0.1 2.0 1 0 0 1 1 1 0 Lines C-terminus AAA_22 PF13401.6 GAM34260.1 - 0.14 12.4 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Cyt-b5 PF00173.28 GAM34261.1 - 0.055 13.6 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.25 GAM34262.1 - 1.1e-72 244.6 0.0 1.6e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM34262.1 - 2.8e-45 154.6 0.0 4.5e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 GAM34262.1 - 4.3e-21 75.0 0.1 1.7e-20 73.1 0.1 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 GAM34262.1 - 9.2e-07 28.5 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAM34262.1 - 1e-06 27.8 0.0 1e-06 27.8 0.0 1.9 3 0 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 GAM34262.1 - 0.025 13.9 0.4 0.073 12.4 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM34262.1 - 0.026 14.5 0.8 0.31 10.9 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM34262.1 - 0.086 11.8 0.7 0.33 9.8 0.7 1.9 1 1 0 1 1 1 0 Haspin like kinase domain VHS PF00790.19 GAM34263.1 - 4.9e-37 126.9 1.7 8.4e-37 126.2 1.7 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 GAM34263.1 - 3e-17 62.0 0.1 4e-16 58.4 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 GAM34263.1 - 1.2e-14 53.9 0.0 2.5e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAM34263.1 - 2.1e-14 52.9 0.0 4.2e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 GAM34263.1 - 5.2e-10 39.5 1.0 5.2e-10 39.5 1.0 2.4 2 1 0 2 2 2 1 GAT domain UIM PF02809.20 GAM34263.1 - 0.023 14.6 2.3 0.068 13.1 2.3 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Hrs_helical PF12210.8 GAM34263.1 - 0.052 14.1 0.1 0.14 12.8 0.1 1.7 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate p450 PF00067.22 GAM34264.1 - 9.6e-62 209.2 0.0 1.4e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 GAM34264.1 - 1.4e-12 47.2 1.9 3.9e-12 45.7 1.9 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM34264.1 - 2e-06 27.8 9.7 4e-06 26.9 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM34265.1 - 1.1e-27 96.7 1.0 1.8e-27 96.1 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM34265.1 - 1.5e-06 28.2 8.3 3.3e-06 27.1 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 GAM34266.1 - 5.4e-79 265.7 0.1 1.4e-78 264.4 0.1 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM34266.1 - 9.7e-15 55.3 0.0 9.7e-14 52.1 0.0 2.4 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Thiolase_C PF02803.18 GAM34267.1 - 3.7e-10 39.5 0.1 4.4e-09 36.0 0.0 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 GAM34267.1 - 5.4e-10 39.1 0.0 5.5e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Fungal_trans_2 PF11951.8 GAM34267.1 - 1.3e-05 24.2 0.7 4.5e-05 22.4 0.7 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.26 GAM34267.1 - 1.6e-05 24.7 0.6 0.00012 21.8 0.2 2.1 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 GAM34267.1 - 4.7e-05 23.2 3.1 0.00049 19.9 0.2 3.0 2 1 1 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 GAM34267.1 - 0.1 12.6 0.0 2.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 GAM34267.1 - 0.11 11.2 0.2 0.19 10.4 0.2 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) UCH_1 PF13423.6 GAM34268.1 - 8.2e-97 324.6 0.2 1.2e-96 324.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase adh_short PF00106.25 GAM34268.1 - 5.6e-30 104.3 0.0 9.8e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM34268.1 - 3.1e-26 92.4 0.1 6e-26 91.4 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.16 GAM34268.1 - 1.2e-18 67.1 22.5 2.7e-17 62.8 22.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily RNase_T PF00929.24 GAM34268.1 - 4.4e-15 56.6 0.0 1e-14 55.4 0.0 1.7 1 0 0 1 1 1 1 Exonuclease KR PF08659.10 GAM34268.1 - 1.6e-06 28.1 3.4 0.0001 22.2 3.4 3.0 1 1 0 1 1 1 1 KR domain UCH PF00443.29 GAM34268.1 - 0.00036 20.1 0.0 0.00086 18.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GTP_EFTU PF00009.27 GAM34269.1 - 2.4e-50 170.8 0.0 3.7e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 GAM34269.1 - 2.9e-18 65.9 5.8 7e-18 64.7 5.8 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 GAM34269.1 - 3.1e-09 37.1 0.2 1e-08 35.5 0.0 2.1 2 0 0 2 2 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 GAM34269.1 - 3.4e-08 33.6 0.1 2.7e-06 27.4 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 GAM34269.1 - 4.1e-07 30.3 0.0 1.3e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Gtr1_RagA PF04670.12 GAM34269.1 - 0.00038 19.9 0.0 0.00082 18.8 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAM34269.1 - 0.0059 16.5 1.3 0.34 10.8 0.3 2.9 3 1 0 3 3 3 1 RsgA GTPase SRPRB PF09439.10 GAM34269.1 - 0.0081 15.6 0.0 1.2 8.6 0.0 2.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 GAM34269.1 - 0.017 14.6 0.2 0.56 9.7 0.1 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 GAM34269.1 - 0.036 14.3 0.0 9.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM34269.1 - 0.036 13.5 0.0 4.8 6.6 0.0 2.3 1 1 1 2 2 2 0 ADP-ribosylation factor family Acyltransf_C PF16076.5 GAM34269.1 - 0.042 13.9 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 Acyltransferase C-terminus Septin PF00735.18 GAM34269.1 - 0.056 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Septin G-alpha PF00503.20 GAM34269.1 - 0.059 12.5 0.3 1.2 8.2 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.23 GAM34269.1 - 0.2 11.7 0.9 11 6.1 0.0 3.0 2 1 1 3 3 3 0 Dynamin family HSP70 PF00012.20 GAM34270.1 - 8.5e-37 126.6 0.1 9.7e-37 126.4 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 GAM34271.1 - 7.7e-218 724.5 8.0 8.7e-218 724.3 8.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAM34271.1 - 1e-16 60.7 0.3 1.6e-16 60.0 0.3 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.10 GAM34271.1 - 0.0016 17.5 0.6 0.013 14.5 0.3 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FIVAR PF07554.13 GAM34271.1 - 0.18 12.6 1.0 14 6.6 0.1 3.4 3 0 0 3 3 3 0 FIVAR domain Haem_degrading PF03928.14 GAM34272.1 - 2.8e-37 127.4 0.2 3.6e-37 127.0 0.2 1.1 1 0 0 1 1 1 1 Haem-degrading Attacin_N PF03768.15 GAM34272.1 - 0.12 12.5 0.1 0.67 10.1 0.0 2.0 2 0 0 2 2 2 0 Attacin, N-terminal region ADH_zinc_N PF00107.26 GAM34273.1 - 5e-25 88.0 0.2 9e-25 87.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM34273.1 - 4.1e-22 78.1 0.6 9.5e-22 77.0 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM34273.1 - 2.2e-06 28.8 0.0 4.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 GAM34273.1 - 0.0039 16.7 0.5 0.0067 15.9 0.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 GAM34273.1 - 0.0041 16.5 1.9 0.007 15.7 1.9 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 GAM34273.1 - 0.067 12.6 0.6 0.11 11.9 0.6 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Vps35 PF03635.17 GAM34274.1 - 0.044 12.3 0.1 0.053 12.0 0.1 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 Bys1 PF04681.12 GAM34275.1 - 4.6e-13 49.4 1.0 5.5e-13 49.1 1.0 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Ion_trans PF00520.31 GAM34276.1 - 6e-07 28.9 4.0 8.6e-07 28.4 4.0 1.2 1 0 0 1 1 1 1 Ion transport protein CEP63 PF17045.5 GAM34276.1 - 0.0086 16.0 0.2 0.014 15.3 0.2 1.2 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa Herpes_BLRF2 PF05812.12 GAM34276.1 - 0.085 13.0 0.3 0.15 12.2 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein CCDC-167 PF15188.6 GAM34276.1 - 0.13 12.6 0.5 0.28 11.5 0.5 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Fe-ADH PF00465.19 GAM34277.1 - 2.8e-104 348.8 0.0 3.6e-104 348.5 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 GAM34277.1 - 1.9e-15 57.2 0.0 5.2e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 GAM34277.1 - 0.0024 17.6 0.1 0.0043 16.8 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Fungal_trans_2 PF11951.8 GAM34278.1 - 6.7e-07 28.5 0.0 1.5e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM34278.1 - 0.00065 19.8 6.0 0.0014 18.7 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM75 PF14650.6 GAM34278.1 - 3.1 7.3 15.9 0.15 11.6 9.7 1.8 2 0 0 2 2 2 0 FAM75 family Fungal_trans PF04082.18 GAM34280.1 - 1.4e-18 66.9 0.0 2.7e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM34280.1 - 2.5e-08 33.9 12.4 3.9e-08 33.3 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.25 GAM34281.1 - 2e-38 131.5 0.0 1.3e-18 67.4 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAM34281.1 - 1.3e-15 57.6 0.0 1e-07 32.2 0.0 4.2 1 1 3 4 4 4 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 GAM34281.1 - 5.2e-05 24.0 0.0 0.7 10.7 0.0 2.8 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 GAM34281.1 - 0.0014 18.8 0.0 2.6 8.2 0.0 2.9 2 1 2 4 4 4 3 Glyoxalase-like domain Glyoxalase_2 PF12681.7 GAM34281.1 - 0.002 18.0 1.5 2.4 8.1 0.0 3.7 4 0 0 4 4 4 1 Glyoxalase-like domain MoaF PF10703.9 GAM34281.1 - 0.0099 15.8 0.0 0.72 9.8 0.0 2.5 2 0 0 2 2 2 1 MoaF N-terminal domain DUF1338 PF07063.13 GAM34281.1 - 0.011 14.9 0.4 17 4.5 0.0 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF1338) NIL PF09383.10 GAM34281.1 - 0.028 14.3 0.0 6.9 6.6 0.0 2.3 2 0 0 2 2 2 0 NIL domain PD40 PF07676.12 GAM34283.1 - 2.2e-39 132.6 19.9 8.4e-07 28.8 1.6 8.7 8 0 0 8 8 8 7 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 GAM34283.1 - 1.3e-10 40.6 1.7 0.075 11.8 0.0 6.0 4 2 1 6 6 6 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF5050 PF16472.5 GAM34283.1 - 0.0056 16.0 1.4 16 4.6 0.0 4.6 5 0 0 5 5 5 2 Domain of unknown function (DUF5050) DUF3748 PF12566.8 GAM34283.1 - 0.088 12.8 0.1 15 5.5 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3748) LysM PF01476.20 GAM34284.1 - 9e-11 41.7 0.2 0.0032 17.5 0.0 4.2 4 0 0 4 4 4 3 LysM domain SLC3A2_N PF16028.5 GAM34285.1 - 0.15 11.6 2.4 0.49 10.0 0.0 2.2 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Ycf70 PF17382.2 GAM34285.1 - 0.26 11.7 1.1 3.9 7.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized Ycf70-like MARVEL PF01284.23 GAM34285.1 - 0.31 11.1 13.5 0.46 10.5 13.5 1.3 1 0 0 1 1 1 0 Membrane-associating domain Glyco_hydro_16 PF00722.21 GAM34286.1 - 1.1e-35 122.7 4.7 1.1e-35 122.7 4.7 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 TMEM51 PF15345.6 GAM34286.1 - 0.0099 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 SKG6 PF08693.10 GAM34286.1 - 0.027 13.9 0.2 0.048 13.1 0.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RTA1 PF04479.13 GAM34287.1 - 8.3e-45 152.9 4.1 1.1e-44 152.5 4.1 1.1 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans PF04082.18 GAM34288.1 - 3.2e-07 29.7 0.5 7.8e-07 28.4 0.5 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM34288.1 - 8.5e-06 25.8 6.9 1.6e-05 24.9 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Malate_DH PF12434.8 GAM34288.1 - 0.096 12.7 0.6 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Beta-lactamase PF00144.24 GAM34289.1 - 2e-26 93.0 0.1 2.8e-26 92.5 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF1633 PF07794.11 GAM34291.1 - 2.1 6.4 6.9 2.7 6.0 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Glyco_hydro_127 PF07944.12 GAM34292.1 - 2.1e-114 382.9 0.1 2.6e-114 382.6 0.1 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Leu_Phe_trans PF03588.14 GAM34292.1 - 0.15 11.6 0.0 1.5 8.4 0.0 2.5 3 0 0 3 3 3 0 Leucyl/phenylalanyl-tRNA protein transferase NYN PF01936.18 GAM34293.1 - 3.4e-32 112.0 0.0 5.2e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 GAM34293.1 - 7.2e-16 57.8 0.0 2.3e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 OST-HTH/LOTUS domain PIN7 PF18475.1 GAM34293.1 - 0.0099 16.5 0.0 0.034 14.8 0.0 1.9 2 0 0 2 2 2 1 PIN domain Acetyltransf_3 PF13302.7 GAM34295.1 - 7.7e-10 39.6 0.0 1.5e-09 38.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM34295.1 - 0.00022 21.4 0.0 0.00047 20.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM34295.1 - 0.019 15.4 0.0 0.035 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAM34295.1 - 0.026 14.7 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PH PF00169.29 GAM34296.1 - 0.0037 17.8 0.0 0.0081 16.7 0.0 1.6 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.18 GAM34296.1 - 0.01 15.8 0.3 0.022 14.7 0.3 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain SIR4_SID PF16991.5 GAM34296.1 - 0.18 11.9 2.6 0.3 11.1 0.5 2.1 2 0 0 2 2 2 0 Sir4 SID domain Arrestin_C PF02752.22 GAM34297.1 - 6e-19 68.8 0.1 1.1e-18 68.0 0.1 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAM34297.1 - 2.7e-08 34.0 0.0 4.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Ysc84 PF04366.12 GAM34299.1 - 5.2e-42 142.6 0.4 1.3e-41 141.3 0.4 1.7 1 0 0 1 1 1 1 Las17-binding protein actin regulator Zds_C PF08632.10 GAM34299.1 - 1.1e-28 98.7 0.6 1.9e-28 97.9 0.6 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term SH3_1 PF00018.28 GAM34299.1 - 6e-13 48.2 0.1 1.8e-12 46.6 0.1 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAM34299.1 - 7.8e-11 41.5 0.1 2.8e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 GAM34299.1 - 3.5e-10 39.6 0.0 7.3e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain EF_assoc_2 PF08356.12 GAM34300.1 - 6.3e-35 119.0 0.0 1.2e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 GAM34300.1 - 3.6e-31 106.6 0.2 6.5e-31 105.8 0.2 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 GAM34300.1 - 2.7e-26 92.1 0.0 6.9e-14 51.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 GAM34300.1 - 7.2e-14 52.0 0.0 5.4e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAM34300.1 - 4.7e-09 36.3 0.0 0.00021 21.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 GAM34300.1 - 3.5e-05 24.3 0.5 0.14 12.5 0.1 3.1 3 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAM34300.1 - 4.3e-05 23.5 0.3 2 8.3 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase EF-hand_1 PF00036.32 GAM34300.1 - 4.5e-05 22.7 3.8 0.067 12.8 0.5 2.6 2 0 0 2 2 2 2 EF hand AAA_29 PF13555.6 GAM34300.1 - 6.3e-05 22.6 0.4 0.043 13.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_6 PF13405.6 GAM34300.1 - 9.4e-05 22.1 3.0 0.03 14.3 0.5 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 GAM34300.1 - 0.00026 21.4 0.9 0.036 14.5 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair Dynamin_N PF00350.23 GAM34300.1 - 0.00026 21.1 0.5 0.66 10.0 0.2 2.6 2 1 0 2 2 2 2 Dynamin family AAA_22 PF13401.6 GAM34300.1 - 0.00053 20.3 0.5 1.6 9.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain GTP_EFTU PF00009.27 GAM34300.1 - 0.0024 17.5 0.1 4.1 6.9 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 GAM34300.1 - 0.0028 18.2 0.0 2 8.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Viral_helicase1 PF01443.18 GAM34300.1 - 0.0064 16.3 0.2 0.15 11.8 0.0 2.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 GAM34300.1 - 0.0085 16.3 0.2 6.9 6.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain EF-hand_10 PF14788.6 GAM34300.1 - 0.011 15.6 2.9 0.069 13.0 0.5 2.5 2 0 0 2 2 2 0 EF hand DUF815 PF05673.13 GAM34300.1 - 0.011 14.9 0.1 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 GAM34300.1 - 0.023 15.3 0.0 1.6 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAM34300.1 - 0.023 15.1 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 GAM34300.1 - 0.027 14.4 0.8 9.9 6.1 0.1 2.8 2 1 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 GAM34300.1 - 0.03 14.0 0.1 0.43 10.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAM34300.1 - 0.04 13.5 0.1 13 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAM34300.1 - 0.048 13.2 0.1 1.7 8.1 0.0 2.4 2 1 0 2 2 2 0 P-loop containing dynein motor region Septin PF00735.18 GAM34300.1 - 0.069 12.4 0.1 0.8 8.9 0.1 2.2 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.17 GAM34300.1 - 0.1 12.3 2.0 15 5.3 0.0 3.1 2 1 0 3 3 3 0 Conserved hypothetical ATP binding protein IIGP PF05049.13 GAM34300.1 - 0.14 11.2 0.7 1.5 7.8 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) EF-hand_5 PF13202.6 GAM34300.1 - 0.16 11.5 6.3 1.3 8.6 0.4 2.6 2 0 0 2 2 2 0 EF hand AAA_23 PF13476.6 GAM34300.1 - 0.25 11.8 0.4 14 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.6 GAM34300.1 - 0.31 10.9 1.2 25 4.8 0.4 2.5 2 0 0 2 2 2 0 EF-hand domain pair ANAPC4_WD40 PF12894.7 GAM34301.1 - 1.5e-11 44.4 0.2 0.0077 16.5 0.0 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAM34301.1 - 1.3e-10 41.6 11.4 0.00084 20.1 0.5 5.6 5 1 0 5 5 5 3 WD domain, G-beta repeat IKI3 PF04762.12 GAM34301.1 - 4e-05 21.8 0.0 0.00067 17.8 0.0 1.9 1 1 1 2 2 2 1 IKI3 family Cytochrom_D1 PF02239.16 GAM34301.1 - 0.0068 15.0 0.0 0.017 13.7 0.0 1.6 2 0 0 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.8 GAM34301.1 - 0.0071 15.1 0.0 0.014 14.1 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 eIF2A PF08662.11 GAM34301.1 - 0.0072 16.2 0.1 0.081 12.8 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Fungal_trans PF04082.18 GAM34302.1 - 2.1e-21 76.2 1.2 2.6e-21 75.9 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM34302.1 - 3.3e-07 30.3 9.7 6e-07 29.5 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DeoC PF01791.9 GAM34303.1 - 6.2e-10 39.1 0.4 7.6e-10 38.8 0.4 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase ArfGap PF01412.18 GAM34304.1 - 0.0045 17.0 0.1 0.0077 16.3 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF908 PF06012.12 GAM34304.1 - 0.38 10.1 8.0 0.55 9.6 8.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SelR PF01641.18 GAM34305.1 - 8.2e-48 161.5 0.1 1.6e-47 160.5 0.1 1.5 1 0 0 1 1 1 1 SelR domain DUF1771 PF08590.10 GAM34305.1 - 7.2e-08 32.7 9.5 1.3e-07 31.8 9.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.16 GAM34305.1 - 2.2e-07 30.4 0.1 1e-05 25.1 0.0 2.8 3 0 0 3 3 3 1 CUE domain Smr PF01713.21 GAM34305.1 - 0.00011 22.5 0.0 0.00097 19.5 0.0 2.5 3 0 0 3 3 3 1 Smr domain HBS1_N PF08938.10 GAM34305.1 - 0.013 15.7 0.0 0.04 14.2 0.0 1.8 1 0 0 1 1 1 0 HBS1 N-terminus GPI-anchored PF10342.9 GAM34306.1 - 1.7e-18 67.2 1.9 1.7e-18 67.2 1.9 2.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family BAGE PF08180.11 GAM34306.1 - 0.061 13.4 0.3 0.061 13.4 0.3 2.0 2 0 0 2 2 2 0 B melanoma antigen family Macoilin PF09726.9 GAM34306.1 - 0.14 10.7 15.4 0.15 10.6 15.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF572 PF04502.13 GAM34306.1 - 1 8.9 6.0 1.1 8.8 6.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RIFIN PF02009.16 GAM34306.1 - 1.6 8.6 6.1 1.9 8.3 6.1 1.2 1 0 0 1 1 1 0 Rifin SOG2 PF10428.9 GAM34306.1 - 3 6.9 28.9 3.6 6.7 28.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Plasmodium_Vir PF05795.11 GAM34306.1 - 3.7 6.9 9.1 5.2 6.4 9.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SPX PF03105.19 GAM34306.1 - 8.1 6.2 14.0 8.7 6.1 14.0 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 GAM34306.1 - 9.2 5.0 17.9 12 4.7 17.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RFX_DNA_binding PF02257.15 GAM34307.1 - 0.052 14.2 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 RFX DNA-binding domain zf_ZIC PF18366.1 GAM34307.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Zic proteins zinc finger domain Meiotic_rec114 PF03525.14 GAM34308.1 - 1.7e-08 33.8 0.4 1.7e-08 33.8 0.4 2.5 2 1 0 2 2 2 2 Meiotic recombination protein rec114 Zn_clus PF00172.18 GAM34309.1 - 1.8e-10 40.8 8.9 3.1e-10 40.0 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SLY PF12485.8 GAM34309.1 - 0.0095 16.7 3.1 1.4 9.6 0.0 2.5 2 0 0 2 2 2 2 Lymphocyte signaling adaptor protein Spt20 PF12090.8 GAM34309.1 - 0.11 12.1 12.6 0.21 11.2 12.6 1.5 1 0 0 1 1 1 0 Spt20 family ASD2 PF08687.11 GAM34309.1 - 0.51 9.9 4.1 0.88 9.1 4.1 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Ndc1_Nup PF09531.10 GAM34309.1 - 0.79 8.3 6.7 1.4 7.6 6.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Copper-fist PF00649.18 GAM34310.1 - 3.5e-21 74.4 2.4 3.5e-21 74.4 2.4 1.9 2 0 0 2 2 2 1 Copper fist DNA binding domain Aminotran_1_2 PF00155.21 GAM34311.1 - 3.2e-41 141.7 0.0 4.5e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RPN7 PF10602.9 GAM34312.1 - 3.9e-55 186.2 0.3 6e-55 185.6 0.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 GAM34312.1 - 1.6e-13 51.0 0.0 3.6e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 PCI domain LigB PF02900.18 GAM34312.1 - 0.016 14.3 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase TPR_7 PF13176.6 GAM34312.1 - 0.045 13.8 0.0 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 GAM34313.1 - 5.2e-13 49.3 0.0 6.8e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM34313.1 - 3.3e-12 46.5 0.0 4.7e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM34313.1 - 5.4e-11 42.8 0.0 7.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAM34313.1 - 1.4e-06 28.6 0.0 2.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM34313.1 - 1.6e-05 24.9 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 GAM34313.1 - 0.0031 17.6 0.0 0.0087 16.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM34313.1 - 0.005 16.8 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Sugar_tr PF00083.24 GAM34314.1 - 1.3e-34 119.9 26.3 1.6e-21 76.7 9.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM34314.1 - 7.2e-16 58.0 56.6 2.1e-15 56.5 34.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PEX11 PF05648.14 GAM34315.1 - 4.4e-75 252.0 0.3 4.9e-75 251.8 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Na_H_Exchanger PF00999.21 GAM34316.1 - 1.9e-44 152.0 11.1 2.6e-44 151.5 11.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 GAM34316.1 - 0.0098 16.0 1.5 0.066 13.3 0.3 3.0 3 0 0 3 3 3 1 YrhC-like protein Lys_export PF03956.13 GAM34316.1 - 0.18 11.3 4.4 0.048 13.2 0.7 2.0 2 0 0 2 2 2 0 Lysine exporter LysO CRCB PF02537.15 GAM34316.1 - 0.37 11.1 4.2 0.51 10.7 0.6 2.9 3 0 0 3 3 3 0 CrcB-like protein, Camphor Resistance (CrcB) PhaG_MnhG_YufB PF03334.14 GAM34316.1 - 7.7 6.8 9.7 13 6.1 0.9 3.5 3 0 0 3 3 3 0 Na+/H+ antiporter subunit Tfb4 PF03850.14 GAM34317.1 - 2.8e-119 397.7 1.0 3.3e-119 397.4 1.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 MMR1 PF08505.10 GAM34317.1 - 0.038 14.3 0.4 0.051 13.9 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein UNC45-central PF11701.8 GAM34318.1 - 6.1e-48 162.7 2.0 2.9e-47 160.5 0.2 3.1 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central TPR_15 PF13429.6 GAM34318.1 - 0.062 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM34318.1 - 0.23 11.7 0.6 0.66 10.2 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Arm PF00514.23 GAM34318.1 - 5.7 7.1 15.6 54 4.0 0.3 7.0 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat GDPD PF03009.17 GAM34319.1 - 1.4e-68 231.5 0.0 2.6e-68 230.6 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 GAM34319.1 - 7.1e-36 122.7 0.8 7.6e-16 58.5 0.1 4.1 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM34319.1 - 6.5e-27 93.5 1.0 9e-12 45.3 0.1 4.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) SPX PF03105.19 GAM34319.1 - 4.5e-23 82.8 3.8 3.6e-11 43.6 0.0 3.5 2 1 1 3 3 3 3 SPX domain Ank_3 PF13606.6 GAM34319.1 - 6.2e-17 60.0 1.2 0.028 14.9 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 GAM34319.1 - 1.3e-16 60.5 0.6 1.4e-07 31.6 0.1 5.7 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM34319.1 - 3.1e-15 55.9 1.0 0.00012 22.3 0.0 6.2 5 0 0 5 5 5 4 Ankyrin repeat MFS_1 PF07690.16 GAM34320.1 - 5.8e-38 130.7 42.2 1.3e-37 129.5 41.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM34320.1 - 8.7e-10 38.0 32.7 3.4e-08 32.8 6.6 3.4 2 1 1 3 3 3 3 Sugar (and other) transporter PRMT5_TIM PF17285.2 GAM34321.1 - 3.3e-74 249.3 0.0 4.4e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 GAM34321.1 - 2.2e-66 223.0 0.0 3.5e-66 222.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 GAM34321.1 - 3.5e-55 186.6 0.0 7.7e-55 185.5 0.0 1.6 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_28 PF02636.17 GAM34321.1 - 0.18 11.4 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase OB_NTP_bind PF07717.16 GAM34322.1 - 1.9e-23 82.6 0.3 1.4e-22 79.8 0.1 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 GAM34322.1 - 5.9e-20 71.6 0.0 1.5e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAM34322.1 - 7.8e-11 42.3 0.0 3.7e-10 40.1 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM34322.1 - 9e-08 32.1 0.3 1.6e-07 31.2 0.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAM34322.1 - 5.8e-06 26.6 0.0 2.4e-05 24.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 GAM34322.1 - 0.00015 21.4 0.3 0.00045 19.9 0.3 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 GAM34322.1 - 0.00063 19.7 0.1 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 GAM34322.1 - 0.0019 18.5 0.1 0.0036 17.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM34322.1 - 0.0078 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAM34322.1 - 0.013 14.6 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 GAM34322.1 - 0.031 14.8 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM34322.1 - 0.037 13.5 0.0 0.095 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF4200 PF13863.6 GAM34323.1 - 0.079 13.4 3.3 9.2 6.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) SlyX PF04102.12 GAM34323.1 - 0.13 12.9 4.5 4.8 7.9 0.1 3.0 2 0 0 2 2 2 0 SlyX EF-hand_6 PF13405.6 GAM34324.1 - 1.4e-07 30.9 0.1 0.004 17.0 0.2 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 GAM34324.1 - 0.00038 20.8 0.5 0.00086 19.7 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 GAM34324.1 - 0.012 15.1 0.0 0.36 10.5 0.0 2.4 2 0 0 2 2 2 0 EF hand DUF1845 PF08900.11 GAM34324.1 - 0.042 13.6 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) DUF2514 PF10721.9 GAM34324.1 - 0.08 13.0 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Met_10 PF02475.16 GAM34325.1 - 0.0024 17.6 0.0 0.0083 15.9 0.0 1.9 1 1 0 1 1 1 1 Met-10+ like-protein Mito_carr PF00153.27 GAM34326.1 - 5.3e-45 151.3 1.3 7.8e-20 70.6 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 GAM34327.1 - 1.5e-46 158.9 0.0 5e-43 147.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM34327.1 - 5.5e-21 75.0 0.0 1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ketoacyl-synt PF00109.26 GAM34327.1 - 1.2e-05 25.1 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain APH PF01636.23 GAM34327.1 - 0.0096 15.9 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM34327.1 - 0.048 12.6 1.7 0.05 12.6 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 GAM34327.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L11 PF00298.19 GAM34328.1 - 4.4e-27 94.4 0.1 6.8e-27 93.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 GAM34328.1 - 1.7e-26 91.8 0.1 2.9e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain DUF3613 PF12266.8 GAM34328.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) Svf1_C PF17187.4 GAM34329.1 - 1.4e-63 213.6 0.1 1.3e-62 210.4 0.0 2.1 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 GAM34329.1 - 8.2e-54 182.1 0.1 1.6e-53 181.1 0.1 1.5 2 0 0 2 2 2 1 Svf1-like N-terminal lipocalin domain CBM_11 PF03425.13 GAM34329.1 - 0.045 13.6 0.2 0.17 11.8 0.2 1.9 2 0 0 2 2 2 0 Carbohydrate binding domain (family 11) Acetyltransf_1 PF00583.25 GAM34330.1 - 0.0022 18.2 0.0 0.0043 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pho86 PF11124.8 GAM34330.1 - 0.0042 16.6 0.2 0.0063 16.0 0.2 1.2 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Acetyltransf_13 PF13880.6 GAM34330.1 - 0.19 11.8 0.3 0.53 10.3 0.3 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DHC_N1 PF08385.12 GAM34331.1 - 3.9e-126 422.0 7.5 3.9e-126 422.0 7.5 4.4 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 GAM34331.1 - 3.1e-115 385.5 9.7 3.1e-115 385.5 9.7 4.6 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 GAM34331.1 - 2.7e-107 358.5 0.2 4.3e-104 348.0 0.0 3.3 3 1 0 3 3 1 1 Hydrolytic ATP binding site of dynein motor region AAA_9 PF12781.7 GAM34331.1 - 2e-75 252.7 1.7 2e-75 252.7 1.7 4.4 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 GAM34331.1 - 4.3e-67 226.2 0.0 1.8e-66 224.2 0.0 2.2 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 GAM34331.1 - 3.8e-42 143.9 0.0 7.1e-36 123.4 0.0 4.7 5 0 0 5 5 4 2 P-loop containing dynein motor region MT PF12777.7 GAM34331.1 - 1.9e-39 135.7 10.1 3.5e-39 134.8 10.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 GAM34331.1 - 1e-33 116.0 0.7 6.4e-27 94.0 0.0 5.1 5 0 0 5 5 4 2 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 GAM34331.1 - 8.9e-32 110.0 0.7 7e-11 42.3 0.0 6.7 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 GAM34331.1 - 3.1e-27 95.4 0.0 7.5e-27 94.2 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 GAM34331.1 - 4.6e-18 65.5 0.2 5.5e-17 62.1 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 GAM34331.1 - 2.7e-15 56.9 0.1 0.0097 16.2 0.0 6.0 4 0 0 4 4 4 3 AAA domain AAA PF00004.29 GAM34331.1 - 6e-14 52.6 0.0 0.00031 21.2 0.0 4.6 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM34331.1 - 2e-09 38.1 0.5 1.2 9.5 0.0 6.9 6 0 0 6 6 5 1 AAA ATPase domain AAA_18 PF13238.6 GAM34331.1 - 4.7e-08 33.6 3.9 0.076 13.6 0.0 5.7 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.6 GAM34331.1 - 5.7e-08 33.0 11.0 0.12 12.5 0.0 6.3 7 0 0 7 7 5 3 AAA domain T2SSE PF00437.20 GAM34331.1 - 8.7e-06 25.0 0.0 0.034 13.2 0.0 3.6 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 GAM34331.1 - 1.7e-05 25.0 0.3 0.0024 18.1 0.0 3.8 3 0 0 3 3 3 1 AAA+ lid domain ABC_tran PF00005.27 GAM34331.1 - 2.7e-05 24.7 0.1 2.7 8.5 0.0 5.0 3 0 0 3 3 3 1 ABC transporter AAA_14 PF13173.6 GAM34331.1 - 6.7e-05 22.9 0.0 1.8 8.6 0.0 4.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 GAM34331.1 - 9.1e-05 22.1 0.1 2.3 8.1 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 GAM34331.1 - 0.00012 21.5 0.6 0.67 9.3 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 GAM34331.1 - 0.00038 20.2 0.2 39 3.9 0.0 4.9 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.18 GAM34331.1 - 0.00041 19.8 1.0 1.7 8.0 0.0 4.0 4 0 0 4 4 3 1 FtsK/SpoIIIE family AAA_19 PF13245.6 GAM34331.1 - 0.0022 18.3 2.8 0.27 11.5 0.0 4.4 5 0 0 5 5 4 1 AAA domain AAA_25 PF13481.6 GAM34331.1 - 0.0026 17.4 0.0 0.3 10.6 0.0 3.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAM34331.1 - 0.0051 16.6 1.2 11 5.6 0.0 4.3 4 0 0 4 4 3 0 AAA domain IstB_IS21 PF01695.17 GAM34331.1 - 0.012 15.4 2.0 0.77 9.5 0.0 4.4 5 0 0 5 5 5 0 IstB-like ATP binding protein Rad17 PF03215.15 GAM34331.1 - 0.014 15.3 0.8 6.8 6.6 0.0 4.3 5 0 0 5 5 4 0 Rad17 P-loop domain RNA_helicase PF00910.22 GAM34331.1 - 0.021 15.2 0.2 71 3.9 0.0 4.8 4 0 0 4 4 4 0 RNA helicase Vps23_core PF09454.10 GAM34331.1 - 0.028 14.4 0.5 1.3 9.0 0.3 3.0 2 0 0 2 2 2 0 Vps23 core domain DUF4482 PF14818.6 GAM34331.1 - 0.057 14.3 10.6 15 6.4 8.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Hemerythrin PF01814.23 GAM34331.1 - 0.16 12.6 3.0 1.6 9.3 0.1 4.3 4 1 1 5 5 2 0 Hemerythrin HHE cation binding domain Phage_GP20 PF06810.11 GAM34331.1 - 2.8 7.7 19.9 4.7 7.0 7.5 4.1 3 0 0 3 3 3 0 Phage minor structural protein GP20 BRE1 PF08647.11 GAM34331.1 - 5.9 7.0 24.2 0.0092 16.0 2.4 4.8 3 0 0 3 3 2 0 BRE1 E3 ubiquitin ligase Ribonuclease_3 PF00636.26 GAM34332.1 - 1.1e-41 141.7 0.0 9.3e-20 71.2 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GAM34332.1 - 2.2e-24 86.0 0.0 2e-12 47.4 0.0 3.8 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 GAM34332.1 - 3.7e-22 78.3 0.0 2.9e-21 75.4 0.0 2.4 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 GAM34332.1 - 1.2e-12 48.1 0.0 5.4e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM34332.1 - 2.5e-12 47.1 0.2 5.8e-12 45.9 0.2 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM34332.1 - 1.1e-09 38.3 0.0 5.7e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 GAM34332.1 - 0.018 14.3 1.1 0.68 9.1 0.0 2.9 3 0 0 3 3 3 0 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 GAM34332.1 - 0.17 11.1 0.0 0.53 9.5 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TAP42 PF04177.12 GAM34333.1 - 7.4e-107 357.2 12.2 8.3e-107 357.0 12.2 1.0 1 0 0 1 1 1 1 TAP42-like family Terminase_4 PF05119.12 GAM34333.1 - 0.018 15.5 0.1 0.053 14.0 0.1 1.9 1 1 0 1 1 1 0 Phage terminase, small subunit Cytochrom_B562 PF07361.11 GAM34333.1 - 0.073 13.7 0.2 0.073 13.7 0.2 2.4 2 1 1 3 3 3 0 Cytochrome b562 DUF725 PF05267.12 GAM34333.1 - 0.087 12.8 0.7 0.17 11.8 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF725) Porphobil_deam PF01379.20 GAM34334.1 - 9.7e-71 237.5 0.0 1.6e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 GAM34334.1 - 2.2e-15 56.7 0.0 4e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Lon_C PF05362.13 GAM34335.1 - 4.7e-69 232.0 0.1 1e-68 230.9 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 GAM34335.1 - 1.3e-29 103.6 0.4 1.3e-29 103.6 0.4 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 GAM34335.1 - 2.6e-24 86.1 0.0 3.4e-23 82.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAM34335.1 - 1.7e-07 31.3 0.0 9.3e-07 28.9 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 GAM34335.1 - 8.3e-07 28.9 0.0 2.1e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 GAM34335.1 - 4.5e-06 27.1 0.3 2.1e-05 25.0 0.0 2.3 2 0 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.17 GAM34335.1 - 0.00018 21.3 0.0 0.00052 19.8 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 GAM34335.1 - 0.00018 21.3 0.1 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 GAM34335.1 - 0.00021 21.1 0.0 0.001 18.9 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM34335.1 - 0.00035 20.8 0.1 0.0062 16.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAM34335.1 - 0.0017 18.5 0.3 0.0077 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 GAM34335.1 - 0.0028 17.8 0.0 0.0097 16.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 GAM34335.1 - 0.0041 16.4 0.0 0.01 15.1 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain NACHT PF05729.12 GAM34335.1 - 0.02 14.8 0.8 0.32 10.9 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA_7 PF12775.7 GAM34335.1 - 0.028 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 GAM34335.1 - 0.031 13.7 0.1 0.083 12.3 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 GAM34335.1 - 0.039 14.0 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAM34335.1 - 0.042 14.2 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 GAM34335.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain DUF815 PF05673.13 GAM34335.1 - 0.048 12.8 0.2 3.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 GAM34335.1 - 0.051 14.1 0.1 0.13 12.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain LmjF365940-deam PF14421.6 GAM34335.1 - 0.061 12.9 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases PhoH PF02562.16 GAM34335.1 - 0.067 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_PrkA PF08298.11 GAM34335.1 - 0.067 12.1 0.1 0.59 9.0 0.1 2.1 2 0 0 2 2 2 0 PrkA AAA domain TniB PF05621.11 GAM34335.1 - 0.095 12.1 0.0 0.31 10.4 0.0 1.9 1 0 0 1 1 1 0 Bacterial TniB protein Zeta_toxin PF06414.12 GAM34335.1 - 0.1 11.9 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 GAM34335.1 - 0.11 12.2 0.1 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAM34335.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 GAM34335.1 - 0.47 11.0 0.0 0.47 11.0 0.0 2.5 2 1 0 2 2 1 0 ABC transporter AAA_23 PF13476.6 GAM34335.1 - 1.3 9.5 0.0 1.3 9.5 0.0 2.9 1 1 1 2 2 1 0 AAA domain Laps PF10169.9 GAM34335.1 - 2.4 8.7 9.3 0.9 10.1 0.1 2.7 2 1 1 3 3 2 0 Learning-associated protein AAA_11 PF13086.6 GAM34335.1 - 4 7.2 9.8 0.19 11.5 0.2 2.4 1 1 1 2 2 2 0 AAA domain Ribosomal_L23 PF00276.20 GAM34336.1 - 4.4e-10 39.8 0.0 8.9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 DUF4519 PF15012.6 GAM34336.1 - 0.0062 16.7 0.5 0.021 15.0 0.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) DUF3141 PF11339.8 GAM34336.1 - 0.053 11.9 0.6 0.071 11.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Pex24p PF06398.11 GAM34336.1 - 0.071 12.1 0.5 0.08 11.9 0.5 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin RIO1 PF01163.22 GAM34337.1 - 1.7e-41 141.9 0.1 1.6e-29 102.9 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 GAM34337.1 - 3.5e-32 110.4 0.0 8.1e-32 109.3 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal Kdo PF06293.14 GAM34337.1 - 3.5e-07 29.8 0.0 1.9e-05 24.1 0.0 2.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM34337.1 - 4.9e-06 26.6 0.0 0.029 14.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family NOA36 PF06524.12 GAM34337.1 - 0.23 10.7 11.0 0.33 10.2 11.0 1.2 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 GAM34337.1 - 0.97 9.2 6.9 1.7 8.4 6.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CobT PF06213.12 GAM34337.1 - 4.2 6.7 14.2 6.2 6.1 14.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RPN1_RPN2_N PF17781.1 GAM34338.1 - 5.6e-117 390.6 6.0 1e-116 389.7 6.0 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 GAM34338.1 - 1.6e-29 101.7 0.0 2.9e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 GAM34338.1 - 3.4e-16 58.8 16.4 0.00028 21.2 0.1 7.8 8 0 0 8 8 8 4 Proteasome/cyclosome repeat AbbA_antirepres PF14156.6 GAM34338.1 - 0.013 15.4 0.3 0.56 10.1 0.1 3.4 2 0 0 2 2 2 0 Antirepressor AbbA DUF4691 PF15762.5 GAM34338.1 - 0.058 13.6 1.1 0.1 12.7 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4691) Mlh1_C PF16413.5 GAM34339.1 - 7.6e-104 346.8 0.0 4.5e-103 344.3 0.0 2.0 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 GAM34339.1 - 1.3e-33 115.2 0.1 2.2e-33 114.5 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 GAM34339.1 - 5.7e-13 48.9 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAM34339.1 - 2.2e-07 31.3 0.0 5.5e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DSPc PF00782.20 GAM34340.1 - 2.4e-28 98.6 0.0 3.5e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM34340.1 - 7.1e-06 25.8 0.0 0.00068 19.3 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAM34340.1 - 0.047 13.8 0.0 0.3 11.2 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate Cupin_8 PF13621.6 GAM34341.1 - 2.6e-30 106.0 0.0 4.8e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 GAM34341.1 - 1e-22 81.0 0.0 1.6e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 GAM34341.1 - 1.1e-21 76.5 5.2 1.4e-06 28.2 0.0 5.5 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM34341.1 - 1.1e-14 54.0 6.6 7.1e-05 22.7 0.1 5.5 6 0 0 6 6 6 3 Kelch motif Cupin_4 PF08007.12 GAM34341.1 - 0.00013 21.5 0.1 0.0011 18.6 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein Kelch_2 PF07646.15 GAM34341.1 - 0.00062 19.6 7.6 0.52 10.4 0.0 5.1 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.6 GAM34341.1 - 0.011 16.0 5.4 0.058 13.7 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM34341.1 - 0.069 13.5 2.5 1.9 8.9 0.1 3.8 3 1 1 4 4 4 0 Kelch motif ANAPC4_WD40 PF12894.7 GAM34342.1 - 0.0022 18.2 0.0 0.67 10.3 0.0 3.6 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 GAM34342.1 - 0.0073 15.9 0.1 10 5.6 0.1 3.0 2 1 0 2 2 2 2 CNH domain Coatomer_WDAD PF04053.14 GAM34342.1 - 0.0092 15.1 0.0 0.15 11.1 0.0 2.2 2 0 0 2 2 2 1 Coatomer WD associated region Hira PF07569.11 GAM34342.1 - 0.03 14.1 0.0 0.8 9.4 0.0 2.8 3 0 0 3 3 3 0 TUP1-like enhancer of split MMS1_N PF10433.9 GAM34342.1 - 0.11 11.1 0.0 1.7 7.2 0.0 2.5 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.32 GAM34342.1 - 0.11 13.4 0.1 24 6.0 0.0 3.8 3 1 1 4 4 4 0 WD domain, G-beta repeat Cupin_5 PF06172.11 GAM34343.1 - 5.4e-47 159.5 0.0 6.6e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) ATP_bind_3 PF01171.20 GAM34344.1 - 8.2e-43 146.3 0.0 4.1e-42 144.0 0.0 2.2 3 1 0 3 3 3 1 PP-loop family RhoGEF PF00621.20 GAM34345.1 - 4.3e-23 82.5 3.7 9e-23 81.4 0.2 2.4 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.8 GAM34345.1 - 1.5e-05 24.8 0.0 3.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) IFT57 PF10498.9 GAM34345.1 - 0.0064 15.5 8.3 0.011 14.7 8.3 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Nod1 PF17114.5 GAM34345.1 - 0.01 16.0 1.0 0.045 13.9 0.0 2.6 3 0 0 3 3 2 1 Gef2-related medial cortical node protein Nod1 RhoGAP PF00620.27 GAM34345.1 - 0.05 13.4 0.1 0.89 9.4 0.0 3.0 2 0 0 2 2 2 0 RhoGAP domain Pox_A_type_inc PF04508.12 GAM34345.1 - 0.089 12.7 0.2 0.43 10.5 0.2 2.3 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat SHE3 PF17078.5 GAM34345.1 - 0.21 11.3 10.7 0.61 9.8 10.6 1.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 CENP-F_leu_zip PF10473.9 GAM34345.1 - 0.26 11.3 14.3 0.26 11.3 12.3 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2937 PF11157.8 GAM34345.1 - 0.31 10.7 2.5 0.89 9.3 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Phage_GP20 PF06810.11 GAM34345.1 - 0.42 10.4 4.9 0.32 10.8 1.0 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 TSC22 PF01166.18 GAM34345.1 - 0.43 10.9 1.6 31 5.0 0.4 3.0 2 0 0 2 2 2 0 TSC-22/dip/bun family Tropomyosin_1 PF12718.7 GAM34345.1 - 2.9 8.0 12.7 0.25 11.5 7.0 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF5344 PF17279.2 GAM34345.1 - 3 8.5 9.0 0.99 10.0 4.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Syntaxin-6_N PF09177.11 GAM34345.1 - 4.1 8.0 5.9 33 5.1 3.8 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FAM76 PF16046.5 GAM34345.1 - 4.9 6.4 7.9 10 5.4 7.9 1.5 1 0 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 GAM34345.1 - 4.9 5.9 14.8 5.7 5.7 5.8 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 GAM34345.1 - 7.5 6.9 6.4 14 6.0 3.2 2.8 1 1 0 2 2 2 0 ABC transporter C-terminal domain APG6_N PF17675.1 GAM34345.1 - 9.1 6.8 13.3 20 5.7 3.2 3.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Sec7 PF01369.20 GAM34346.1 - 5.9e-61 205.3 0.0 9.7e-61 204.6 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GAM34346.1 - 5.3e-18 65.4 0.0 6.1e-17 62.0 0.0 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal nsp7 PF08716.10 GAM34346.1 - 0.44 11.2 2.6 23 5.7 0.1 3.8 3 0 0 3 3 3 0 nsp7 replicase TPR_14 PF13428.6 GAM34347.1 - 1.3e-13 50.5 14.5 0.74 10.8 0.0 11.5 11 2 2 13 13 12 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM34347.1 - 7.3e-09 35.2 5.2 0.15 12.4 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat Suf PF05843.14 GAM34347.1 - 4.3e-08 33.5 13.5 0.72 9.8 0.3 6.1 3 2 2 6 6 6 4 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 GAM34347.1 - 2.4e-07 30.7 13.9 0.075 13.0 0.1 7.2 6 3 2 8 8 8 3 Mad3/BUB1 homology region 1 TPR_19 PF14559.6 GAM34347.1 - 7.9e-07 29.5 0.0 19 5.9 0.0 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM34347.1 - 2e-06 28.0 4.9 0.96 9.8 0.0 7.0 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM34347.1 - 1.2e-05 25.1 15.7 3.4 8.0 0.0 8.0 9 0 0 9 9 9 3 Tetratricopeptide repeat NRDE-2 PF08424.10 GAM34347.1 - 0.021 14.0 16.9 0.065 12.4 0.0 6.2 3 2 3 7 7 7 0 NRDE-2, necessary for RNA interference MIT PF04212.18 GAM34347.1 - 0.041 14.0 0.1 1.9 8.6 0.1 3.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Ribosomal_S24e PF01282.19 GAM34347.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S24e TPR_17 PF13431.6 GAM34347.1 - 0.34 11.4 9.8 3.4 8.3 0.0 6.4 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM34347.1 - 0.4 10.6 5.4 1.3e+02 2.7 0.4 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat HAT PF02184.16 GAM34347.1 - 7.2 6.7 12.0 2.8 8.0 0.0 5.5 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat ATP-synt_D PF01813.17 GAM34348.1 - 1.2e-68 230.9 3.4 1.6e-68 230.4 3.4 1.2 1 0 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 GAM34348.1 - 0.059 12.9 0.2 0.086 12.3 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) CobA_CobO_BtuR PF02572.15 GAM34348.1 - 0.31 11.3 3.7 0.58 10.4 0.1 2.4 2 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP RRM_1 PF00076.22 GAM34349.1 - 6.9e-27 93.1 0.3 2.1e-12 46.7 0.3 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM34349.1 - 1.2e-06 28.1 0.0 5.5e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 GAM34349.1 - 0.018 15.1 0.0 0.066 13.3 0.0 1.9 2 0 0 2 2 2 0 Limkain b1 DUF45 PF01863.17 GAM34349.1 - 0.078 13.0 0.2 0.1 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 PHM7_cyt PF14703.6 GAM34349.1 - 0.095 12.9 0.6 3.8 7.7 0.0 2.9 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF4523 PF15023.6 GAM34349.1 - 0.2 11.5 0.0 0.49 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) TFCD_C PF12612.8 GAM34350.1 - 1.2e-39 136.2 0.6 6.2e-39 133.8 0.1 2.4 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 GAM34350.1 - 2.3e-06 27.4 13.4 0.44 10.9 0.1 7.3 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 GAM34350.1 - 0.00014 22.2 4.0 7.6 7.0 0.1 5.9 5 1 0 5 5 5 2 HEAT repeats IFRD PF05004.13 GAM34350.1 - 0.0029 16.8 5.3 0.016 14.3 0.1 3.7 3 1 0 4 4 4 1 Interferon-related developmental regulator (IFRD) DUF2496 PF10689.9 GAM34350.1 - 0.039 13.7 0.3 0.13 12.1 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2496) Vac14_Fab1_bd PF12755.7 GAM34350.1 - 0.12 12.9 0.1 43 4.8 0.0 4.1 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Pkinase PF00069.25 GAM34351.1 - 9.3e-61 205.5 0.0 1.6e-60 204.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM34351.1 - 1.4e-36 126.1 0.0 2.2e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 GAM34351.1 - 8.8e-30 102.6 13.4 3.8e-15 55.8 4.9 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 GAM34351.1 - 5.7e-21 74.2 29.9 2.8e-12 46.3 9.7 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 GAM34351.1 - 4.1e-14 53.0 1.2 1.6e-13 51.1 1.2 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 GAM34351.1 - 3.7e-07 30.4 0.0 7.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 GAM34351.1 - 0.005 16.2 0.0 0.0099 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 GAM34351.1 - 0.053 13.1 1.6 0.32 10.6 0.0 2.5 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Uds1 PF15456.6 GAM34351.1 - 3.9 7.7 8.0 2.2 8.5 1.4 2.6 2 0 0 2 2 2 0 Up-regulated During Septation zf-RING_9 PF13901.6 GAM34351.1 - 6.3 6.7 22.9 4.2 7.3 8.0 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon FYVE_2 PF02318.16 GAM34351.1 - 6.8 6.9 20.7 7.8 6.7 6.3 2.8 1 1 1 2 2 2 0 FYVE-type zinc finger MFS_1 PF07690.16 GAM34352.1 - 3.8e-29 101.7 61.1 9.3e-13 47.8 8.5 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 GAM34352.1 - 1.6e-06 26.9 20.5 4.4e-05 22.2 3.5 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein eIF-1a PF01176.19 GAM34353.1 - 1.8e-18 66.1 0.0 2.5e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.13 GAM34354.1 - 1.9e-135 451.9 13.0 2.5e-135 451.5 13.0 1.1 1 0 0 1 1 1 1 ALG3 protein COA2 PF17051.5 GAM34354.1 - 0.034 14.2 0.1 0.074 13.1 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase assembly factor 2 Metallophos PF00149.28 GAM34355.1 - 8.6e-31 108.0 0.0 5.2e-22 79.4 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAM34355.1 - 0.13 12.7 0.1 0.33 11.4 0.1 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Ank_4 PF13637.6 GAM34356.1 - 9.5e-36 121.7 0.1 1.4e-10 41.5 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM34356.1 - 1.8e-32 111.8 0.0 2.4e-10 40.9 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 GAM34356.1 - 2.2e-28 97.4 0.2 4.5e-05 23.7 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 GAM34356.1 - 2.2e-26 89.0 0.0 0.00074 19.8 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 GAM34356.1 - 5.2e-25 87.2 0.2 7.2e-07 29.4 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) VWA_3_C PF18571.1 GAM34356.1 - 0.35 10.8 2.3 86 3.1 0.0 3.4 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain Fungal_trans PF04082.18 GAM34357.1 - 2.5e-40 138.2 0.0 4.7e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM34357.1 - 1.9e-07 31.1 8.0 4e-07 30.0 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 GAM34357.1 - 0.0039 17.1 3.8 0.01 15.7 3.8 1.7 1 0 0 1 1 1 1 PHD-finger Methyltransf_25 PF13649.6 GAM34359.1 - 2e-10 41.2 0.0 4.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM34359.1 - 6.3e-08 32.6 0.0 9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM34359.1 - 0.00033 21.3 0.0 0.00057 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 GAM34359.1 - 0.034 13.6 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain DNA_ligase_A_M PF01068.21 GAM34360.1 - 9.8e-46 156.0 0.0 4.8e-45 153.7 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAM34360.1 - 2.9e-45 154.7 0.0 1.1e-44 152.8 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 GAM34360.1 - 1.9e-21 76.3 0.1 1.2e-15 57.7 0.0 2.9 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 GAM34360.1 - 9.2e-19 67.9 0.1 3.8e-17 62.7 0.0 3.2 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 GAM34360.1 - 2.5e-17 63.7 0.0 5.5e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 GAM34360.1 - 2.3e-09 37.5 0.1 2.3e-06 27.9 0.0 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 GAM34360.1 - 4.8e-05 23.6 0.5 0.057 13.7 0.0 2.7 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 GAM34360.1 - 0.00018 21.3 2.0 0.019 14.9 0.1 2.8 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain DNA_ligase_IV PF11411.8 GAM34360.1 - 0.013 15.6 0.1 0.035 14.2 0.1 1.7 1 0 0 1 1 1 0 DNA ligase IV Fungal_trans PF04082.18 GAM34361.1 - 3.8e-07 29.4 2.3 7.2e-06 25.2 0.2 2.8 2 2 1 3 3 3 2 Fungal specific transcription factor domain EF-hand_4 PF12763.7 GAM34362.1 - 9.2e-05 22.4 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Dicty_REP PF05086.12 GAM34362.1 - 9.5 4.1 5.2 13 3.6 5.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Fungal_trans PF04082.18 GAM34363.1 - 8.4e-05 21.7 0.2 0.00019 20.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM34363.1 - 0.00015 21.8 6.4 0.00027 21.0 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spb1_C PF07780.12 GAM34365.1 - 9.3e-86 286.8 24.3 9.3e-86 286.8 24.3 2.9 2 1 1 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 GAM34365.1 - 7.1e-56 189.1 0.0 1.4e-55 188.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 GAM34365.1 - 1.6e-50 171.1 14.0 1.6e-50 171.1 14.0 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 GAM34365.1 - 0.019 14.8 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 GAM34366.1 - 6.6e-76 254.4 0.0 1e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 HC2 PF07382.11 GAM34366.1 - 6.5 6.8 7.0 0.56 10.3 0.8 2.0 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 ATG16 PF08614.11 GAM34367.1 - 3e-53 181.0 33.7 5.7e-53 180.1 33.7 1.4 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF1180 PF06679.12 GAM34367.1 - 0.17 12.3 6.7 0.27 11.6 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) GrpE PF01025.19 GAM34367.1 - 0.23 11.1 10.9 0.064 12.9 2.6 2.2 2 0 0 2 2 2 0 GrpE YabA PF06156.13 GAM34367.1 - 0.31 11.7 14.3 0.27 11.9 1.2 3.0 2 1 1 3 3 3 0 Initiation control protein YabA NPV_P10 PF05531.12 GAM34367.1 - 0.46 11.0 5.8 0.31 11.5 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 GAM34367.1 - 0.98 8.7 21.8 2.2 7.5 21.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 GAM34367.1 - 1.3 8.5 12.9 1.8 8.0 12.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TFIIA PF03153.13 GAM34367.1 - 1.9 8.4 15.8 2.3 8.1 15.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 GAM34367.1 - 2.1 7.0 7.8 2.3 6.8 7.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spc7 PF08317.11 GAM34367.1 - 6.6 5.5 19.6 2 7.2 6.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Ras PF00071.22 GAM34368.1 - 2.6e-40 137.7 0.2 1.9e-24 86.1 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 GAM34368.1 - 1.7e-19 70.2 0.1 1.4e-12 47.9 0.1 2.2 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM34368.1 - 3.5e-05 23.3 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAM34368.1 - 0.00018 21.5 0.2 0.0041 17.0 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 GAM34368.1 - 0.0011 19.1 0.1 0.0022 18.1 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 GAM34368.1 - 0.0025 17.5 0.1 0.11 12.3 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 GAM34368.1 - 0.0041 16.4 0.1 0.069 12.4 0.0 2.1 2 0 0 2 2 2 1 Septin AAA_16 PF13191.6 GAM34368.1 - 0.0048 17.3 0.0 0.0059 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM34368.1 - 0.0079 16.5 0.0 0.014 15.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAM34368.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 GAM34368.1 - 0.023 14.3 0.1 0.099 12.2 0.0 1.8 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 GAM34368.1 - 0.025 14.1 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 GAM34368.1 - 0.036 14.1 0.0 0.093 12.7 0.0 1.7 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 GAM34368.1 - 0.063 13.2 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 GAM34368.1 - 0.095 12.5 0.1 3.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 GAM34368.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 GAM34368.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NB-ARC PF00931.22 GAM34368.1 - 0.14 11.3 0.4 0.34 10.1 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 GAM34368.1 - 0.16 12.4 0.2 0.34 11.3 0.2 1.8 1 1 0 1 1 1 0 RNA helicase DAP3 PF10236.9 GAM34368.1 - 0.2 10.8 0.1 0.29 10.2 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 EamA PF00892.20 GAM34369.1 - 3e-13 50.1 38.7 3.6e-07 30.4 5.6 3.1 3 0 0 3 3 3 3 EamA-like transporter family DUF3955 PF13127.6 GAM34369.1 - 3.7e-05 23.5 1.5 3.7e-05 23.5 1.5 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) UAA PF08449.11 GAM34369.1 - 0.00011 21.5 8.1 0.00011 21.5 8.1 1.9 2 0 0 2 2 2 1 UAA transporter family PUNUT PF16913.5 GAM34369.1 - 0.0066 15.7 0.2 0.0066 15.7 0.2 2.8 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 GAM34369.1 - 0.0068 16.0 14.5 0.058 12.9 7.8 3.0 2 1 0 2 2 2 2 Solute carrier family 35 DUF5389 PF17364.2 GAM34369.1 - 0.51 10.4 8.4 0.05 13.7 1.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5389) COX8 PF02285.15 GAM34369.1 - 5.9 6.8 9.8 0.28 11.1 0.8 3.3 3 0 0 3 3 3 0 Cytochrome oxidase c subunit VIII CoA_binding_3 PF13727.6 GAM34369.1 - 8.1 6.4 15.8 0.27 11.3 3.3 2.5 2 0 0 2 2 2 0 CoA-binding domain PH PF00169.29 GAM34370.1 - 4.9e-25 88.1 0.3 2.9e-12 47.0 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 GAM34370.1 - 1.5e-11 44.7 0.1 0.00022 21.6 0.1 4.2 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 GAM34370.1 - 3.7e-08 33.7 0.5 0.00024 21.5 0.1 3.3 2 2 0 2 2 2 2 Pleckstrin homology domain BCL_N PF04714.13 GAM34370.1 - 0.12 12.5 0.2 0.27 11.3 0.2 1.5 1 0 0 1 1 1 0 BCL7, N-terminal conserver region Glyco_transf_15 PF01793.16 GAM34371.1 - 1e-80 271.4 10.8 8e-79 265.2 10.8 2.6 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase OPT PF03169.15 GAM34372.1 - 1.1e-173 579.2 53.2 1.3e-173 579.0 53.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein E1-E2_ATPase PF00122.20 GAM34372.1 - 1.9 7.9 4.2 1.2 8.6 1.2 2.2 2 0 0 2 2 2 0 E1-E2 ATPase p450 PF00067.22 GAM34373.1 - 3e-51 174.6 0.0 6e-51 173.6 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 Ring_hydroxyl_A PF00848.19 GAM34374.1 - 1.3e-14 54.6 3.0 1.2e-10 41.7 1.8 2.2 1 1 0 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 GAM34374.1 - 0.018 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain Beach PF02138.18 GAM34374.1 - 0.02 14.3 1.1 0.034 13.5 0.2 1.8 2 0 0 2 2 2 0 Beige/BEACH domain Orai-1 PF07856.12 GAM34374.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Mediator of CRAC channel activity Fungal_trans PF04082.18 GAM34375.1 - 2.1e-07 30.3 0.1 3.7e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAM34375.1 - 8e-06 26.0 24.7 0.00068 20.0 2.6 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM34375.1 - 0.001 19.7 14.5 0.14 13.1 1.6 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 GAM34375.1 - 0.0064 16.8 2.9 0.014 15.7 2.9 1.6 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-met PF12874.7 GAM34375.1 - 0.053 13.9 1.4 8.8 6.9 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 GAM34375.1 - 0.44 11.2 4.2 1.4 9.6 3.9 1.9 1 1 0 1 1 1 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 GAM34375.1 - 6.3 7.4 15.7 0.36 11.3 3.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Oxidored_FMN PF00724.20 GAM34376.1 - 1.2e-90 304.2 0.0 1.5e-90 304.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_binding_3 PF01494.19 GAM34377.1 - 3.2e-72 243.7 0.0 4.1e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAM34377.1 - 1.6e-18 67.3 0.0 3.2e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 GAM34377.1 - 0.00019 20.7 0.0 0.0011 18.2 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM34377.1 - 0.00022 21.7 0.0 0.0005 20.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM34377.1 - 0.00027 19.8 0.0 0.00044 19.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 GAM34377.1 - 0.00049 19.8 0.0 0.0013 18.4 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM34377.1 - 0.00051 20.2 0.0 0.0017 18.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM34377.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAM34377.1 - 0.0017 17.7 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 GAM34377.1 - 0.014 14.5 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 GAM34377.1 - 0.024 13.9 0.1 0.048 12.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 GAM34377.1 - 0.024 13.7 0.1 0.046 12.8 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 GAM34377.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 GAM34377.1 - 0.1 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_9 PF13454.6 GAM34377.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 GAM34377.1 - 0.14 11.5 0.0 0.53 9.6 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 GAM34377.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 GAM34377.1 - 0.24 10.4 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short_C2 PF13561.6 GAM34378.1 - 2.8e-57 194.0 0.1 3.2e-57 193.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM34378.1 - 1.6e-41 141.9 0.0 2.1e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM34378.1 - 6.3e-09 36.0 0.1 1.4e-08 34.9 0.1 1.7 1 1 0 1 1 1 1 KR domain FAD_binding_3 PF01494.19 GAM34379.1 - 2.9e-13 49.8 0.3 7.3e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 GAM34379.1 - 1.4e-08 34.1 3.5 1.9e-05 23.7 0.1 2.2 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 GAM34379.1 - 2.2e-07 30.4 0.7 0.013 14.8 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM34379.1 - 2.9e-06 26.2 2.3 1.5e-05 23.9 2.3 1.8 1 1 0 1 1 1 1 HI0933-like protein DAO PF01266.24 GAM34379.1 - 6.6e-06 25.9 6.0 0.022 14.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAM34379.1 - 1.1e-05 24.7 1.1 2.6e-05 23.5 1.1 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAM34379.1 - 0.00069 18.8 8.3 0.0019 17.4 6.6 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 GAM34379.1 - 0.0039 16.5 0.6 0.12 11.6 1.5 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM34379.1 - 0.0046 17.5 0.9 3.1 8.4 0.7 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Tfb2_C PF18307.1 GAM34379.1 - 0.017 15.5 0.0 0.21 12.0 0.0 2.3 2 0 0 2 2 2 0 Transcription factor Tfb2 (p52) C-terminal domain NAD_binding_8 PF13450.6 GAM34379.1 - 0.056 13.7 4.2 0.12 12.7 3.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 GAM34379.1 - 0.076 12.9 1.0 0.13 12.1 1.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 GAM34379.1 - 0.14 11.5 3.9 0.28 10.5 3.3 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.10 GAM34379.1 - 0.22 10.6 0.0 1.1 8.2 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.22 GAM34379.1 - 1.1 8.3 7.8 0.41 9.7 5.3 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Polysacc_deac_1 PF01522.21 GAM34380.1 - 2.3e-19 69.5 0.0 4.4e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 GAM34380.1 - 7.7e-05 22.4 0.1 0.00014 21.6 0.1 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 GAM34380.1 - 0.043 12.2 0.0 0.057 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Peroxidase_2 PF01328.17 GAM34380.1 - 0.17 12.4 0.0 0.25 11.8 0.0 1.4 1 1 0 1 1 1 0 Peroxidase, family 2 Amidase PF01425.21 GAM34381.1 - 3.9e-66 223.9 0.0 2.9e-32 112.2 0.0 2.1 1 1 1 2 2 2 2 Amidase Thioesterase PF00975.20 GAM34381.1 - 0.12 12.4 0.0 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain 2OG-FeII_Oxy PF03171.20 GAM34382.1 - 1.3e-12 48.1 0.0 2.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily His_Phos_1 PF00300.22 GAM34383.1 - 5.6e-15 55.5 0.0 7.5e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF1248 PF06852.12 GAM34383.1 - 0.12 11.8 0.0 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1248) HECT PF00632.25 GAM34384.1 - 2.1e-67 227.8 0.0 4.8e-67 226.6 0.0 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 GAM34384.1 - 2.6e-21 75.6 2.3 2.6e-21 75.6 2.3 2.1 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A ADH_N PF08240.12 GAM34385.1 - 1.7e-09 37.5 0.2 2e-08 34.0 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM34385.1 - 5.1e-09 36.2 0.0 1.5e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM34385.1 - 1.7e-06 29.1 0.0 2.8e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 GAM34385.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain zf-C2H2_2 PF12756.7 GAM34386.1 - 3.1e-36 123.7 14.9 5.1e-30 103.8 5.0 3.5 3 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 GAM34386.1 - 5.5e-08 32.9 4.5 5.5e-08 32.9 4.5 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAM34386.1 - 9.1e-07 29.0 14.4 1.1e-06 28.7 6.2 3.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 GAM34386.1 - 0.011 16.2 14.6 0.39 11.3 0.2 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM34386.1 - 0.017 15.9 12.9 0.39 11.7 0.5 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger Cytochrome-c551 PF10643.9 GAM34386.1 - 0.27 10.8 0.9 7 6.2 0.1 2.2 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 zf-C2H2_6 PF13912.6 GAM34386.1 - 4 7.5 10.6 1.6 8.8 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DUF21 PF01595.20 GAM34387.1 - 3.9e-32 111.4 0.1 7.5e-32 110.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 GAM34387.1 - 1e-06 29.0 0.4 0.034 14.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain UPF0270 PF06794.12 GAM34387.1 - 0.76 9.9 2.5 34 4.6 0.4 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0270) Transket_pyr PF02779.24 GAM34388.1 - 4.3e-41 140.5 0.1 7.8e-41 139.7 0.1 1.4 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAM34388.1 - 1e-31 109.4 0.1 2.1e-31 108.4 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 GAM34388.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Spc7 PF08317.11 GAM34389.1 - 0.00014 20.9 7.7 0.00014 20.9 7.7 3.2 1 1 1 3 3 3 2 Spc7 kinetochore protein HALZ PF02183.18 GAM34389.1 - 0.27 11.5 14.4 3.3 8.0 0.3 5.3 5 0 0 5 5 5 0 Homeobox associated leucine zipper Fungal_TACC PF12709.7 GAM34389.1 - 1 9.9 14.8 1.8 9.1 0.4 5.4 4 2 1 5 5 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins Filament PF00038.21 GAM34389.1 - 1.1 8.7 45.5 6.8 6.2 2.6 4.0 1 1 1 2 2 2 0 Intermediate filament protein TMF_DNA_bd PF12329.8 GAM34389.1 - 2.8 8.0 19.4 3.6 7.7 0.4 4.6 5 1 0 5 5 5 0 TATA element modulatory factor 1 DNA binding Pox_A_type_inc PF04508.12 GAM34389.1 - 6.7 6.7 14.3 5.3 7.1 0.3 5.2 6 1 0 6 6 6 0 Viral A-type inclusion protein repeat Acetyltransf_2 PF00797.17 GAM34390.1 - 4.4e-42 144.5 0.0 5.5e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase DUF1847 PF08901.11 GAM34390.1 - 0.034 13.8 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) RecT PF03837.14 GAM34390.1 - 0.083 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 RecT family KCH PF16944.5 GAM34391.1 - 1.5e-103 346.0 6.9 1.8e-103 345.7 6.9 1.1 1 0 0 1 1 1 1 Fungal potassium channel Fzo_mitofusin PF04799.13 GAM34391.1 - 0.24 10.9 0.3 0.39 10.2 0.3 1.2 1 0 0 1 1 1 0 fzo-like conserved region Glyoxalase PF00903.25 GAM34392.1 - 9.6e-22 77.5 0.1 2.9e-16 59.8 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAM34392.1 - 8e-12 45.4 0.1 3.2e-05 24.2 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 GAM34392.1 - 2.7e-06 27.6 0.0 0.0022 18.2 0.0 2.3 2 0 0 2 2 2 2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 GAM34392.1 - 6e-05 23.2 0.1 0.32 11.1 0.3 3.0 2 1 0 2 2 2 2 Glyoxalase-like domain HgmA PF04209.13 GAM34393.1 - 6.5e-208 690.6 0.2 7.4e-208 690.4 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase TPR_17 PF13431.6 GAM34396.1 - 0.088 13.2 0.1 3.4 8.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat FAA_hydrolase PF01557.18 GAM34397.1 - 3.9e-55 186.9 0.0 5.8e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 GAM34397.1 - 1.4e-28 99.1 0.0 2.3e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal GST_N_2 PF13409.6 GAM34398.1 - 1.8e-10 40.9 0.2 1e-09 38.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAM34398.1 - 5.3e-08 33.1 0.0 8.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM34398.1 - 1.1e-07 31.9 0.0 2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM34398.1 - 1.8e-06 28.1 0.0 4.8e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM34398.1 - 5.1e-06 26.8 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM34398.1 - 0.00071 19.6 0.0 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_92 PF07971.12 GAM34399.1 - 5.6e-149 497.0 4.1 6.7e-149 496.7 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 GAM34399.1 - 5.2e-64 216.4 0.2 8.4e-64 215.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain DUF747 PF05346.11 GAM34401.1 - 8.4e-120 400.0 8.5 1.1e-119 399.6 8.5 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Methyltransf_25 PF13649.6 GAM34402.1 - 1.3e-08 35.5 0.0 2.7e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM34402.1 - 2.6e-06 28.1 0.0 5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM34402.1 - 2.6e-06 27.4 0.0 3.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM34402.1 - 0.00015 22.3 0.0 0.0003 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 GAM34402.1 - 0.00019 20.7 0.4 0.02 14.1 0.0 2.4 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Peptidase_M20 PF01546.28 GAM34403.1 - 2.9e-21 76.1 0.0 9e-21 74.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 GAM34403.1 - 3e-10 40.5 6.5 0.0048 17.7 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat M20_dimer PF07687.14 GAM34403.1 - 5.9e-07 29.4 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Sugar_tr PF00083.24 GAM34404.1 - 7.2e-90 302.0 31.8 8.3e-90 301.8 31.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM34404.1 - 6.2e-28 97.7 34.2 2.3e-15 56.4 13.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Lipase_GDSL_2 PF13472.6 GAM34405.1 - 3e-19 70.1 0.0 5.9e-19 69.1 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAM34405.1 - 8e-14 52.1 0.0 3.3e-13 50.1 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AP_endonuc_2 PF01261.24 GAM34405.1 - 0.033 13.6 0.0 0.086 12.3 0.0 1.5 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel CP_ATPgrasp_1 PF04174.13 GAM34405.1 - 0.068 12.2 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 A circularly permuted ATPgrasp TraQ PF09679.10 GAM34406.1 - 0.043 13.7 0.4 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF349 PF03993.12 GAM34406.1 - 0.28 11.5 6.7 0.2 12.0 2.1 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Zn_clus PF00172.18 GAM34407.1 - 2.9e-06 27.3 12.7 4.8e-06 26.6 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GNVR PF13807.6 GAM34408.1 - 0.52 10.3 3.4 7.3 6.6 0.5 2.8 1 1 1 2 2 2 0 G-rich domain on putative tyrosine kinase SpoIIIAC PF06686.11 GAM34408.1 - 2.3 8.4 11.3 14 6.0 0.0 3.4 3 1 0 3 3 3 0 Stage III sporulation protein AC/AD protein family Tetraspanin PF00335.20 GAM34408.1 - 3.4 7.3 8.0 2.1 8.0 5.4 1.8 1 1 0 1 1 1 0 Tetraspanin family DHHC PF01529.20 GAM34408.1 - 3.5 7.8 6.3 1.4 9.1 1.6 2.5 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF2070 PF09843.9 GAM34408.1 - 4.5 5.4 11.3 0.2 9.9 4.8 1.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2070) PsbH PF00737.20 GAM34408.1 - 5.3 6.9 7.9 6.2 6.6 1.1 2.9 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein COesterase PF00135.28 GAM34409.1 - 3.1e-84 283.7 0.0 4.2e-84 283.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM34409.1 - 2.2e-06 27.7 0.0 1e-05 25.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM34409.1 - 0.0026 17.3 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family eIF_4EBP PF05456.11 GAM34409.1 - 0.099 12.6 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Abhydrolase_3 PF07859.13 GAM34410.1 - 3.2e-42 144.8 0.0 5.5e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAM34410.1 - 4.7e-11 42.2 0.1 1.8e-10 40.3 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Cyclase PF04199.13 GAM34410.1 - 8.9e-08 32.5 0.0 2.1e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Putative cyclase Abhydrolase_6 PF12697.7 GAM34410.1 - 0.0023 18.6 0.1 0.0053 17.4 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM34410.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 p450 PF00067.22 GAM34411.1 - 1.2e-70 238.5 0.0 9.9e-70 235.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Oxidored_FMN PF00724.20 GAM34411.1 - 5.1e-62 210.1 0.0 7e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 GAM34411.1 - 0.059 12.4 0.0 2 7.4 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) FAD_binding_3 PF01494.19 GAM34412.1 - 4.5e-13 49.2 5.0 7.8e-10 38.5 0.0 2.6 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAM34412.1 - 3.5e-08 33.0 2.6 5e-07 29.2 2.6 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM34412.1 - 5.8e-06 26.5 0.3 1.3e-05 25.3 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAM34412.1 - 7.1e-05 23.3 1.4 0.0012 19.4 1.4 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM34412.1 - 0.00041 20.1 4.1 0.00041 20.1 4.1 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAM34412.1 - 0.00043 19.6 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM34412.1 - 0.0012 18.1 1.6 0.31 10.2 0.1 2.2 2 0 0 2 2 2 2 Thi4 family FAD_oxidored PF12831.7 GAM34412.1 - 0.0017 17.8 1.8 0.0033 16.9 0.8 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM34412.1 - 0.0042 16.2 3.7 0.0054 15.9 2.5 1.8 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 GAM34412.1 - 0.0058 15.5 2.0 0.5 9.1 0.4 2.8 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 GAM34412.1 - 0.0081 14.9 1.7 0.012 14.3 1.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 GAM34412.1 - 0.023 14.0 0.4 3.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 GAM34412.1 - 0.032 13.3 4.6 0.84 8.6 1.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 GAM34412.1 - 0.087 11.9 2.2 0.15 11.1 2.0 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.10 GAM34412.1 - 0.11 11.5 0.0 2.9 6.9 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.6 GAM34412.1 - 0.14 12.1 1.9 10 6.1 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding p450 PF00067.22 GAM34413.1 - 5.6e-66 223.2 0.0 7.4e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-CHY PF05495.12 GAM34414.1 - 0.12 12.8 18.9 0.075 13.5 5.6 4.1 3 2 0 3 3 3 0 CHY zinc finger zf_CCCH_4 PF18345.1 GAM34414.1 - 0.89 9.7 9.9 0.068 13.2 3.9 2.3 2 0 0 2 2 2 0 Zinc finger domain DUF3295 PF11702.8 GAM34415.1 - 3.8e-179 597.2 21.9 4.4e-179 597.0 21.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 GAM34415.1 - 1.7e-11 43.7 2.1 3.2e-11 42.8 2.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Abhydrolase_6 PF12697.7 GAM34416.1 - 0.00076 20.1 0.1 0.0011 19.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cpn60_TCP1 PF00118.24 GAM34417.1 - 1.7e-157 525.0 4.0 1.9e-157 524.8 4.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Chromo_shadow PF01393.19 GAM34418.1 - 5e-15 55.3 0.6 2.5e-12 46.7 0.1 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 GAM34418.1 - 1.2e-07 31.5 0.6 2.1e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Senescence_reg PF04520.13 GAM34418.1 - 0.35 11.7 4.8 0.41 11.5 1.2 2.0 1 1 0 2 2 2 0 Senescence regulator Rap1_C PF11626.8 GAM34419.1 - 1.9e-22 79.2 0.3 8e-22 77.1 0.0 2.2 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 GAM34419.1 - 2.1e-21 75.9 1.9 3.7e-21 75.1 1.0 1.9 2 0 0 2 2 2 1 Rap1 Myb domain BRCT_2 PF16589.5 GAM34419.1 - 2.2e-07 31.2 0.0 5.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 GAM34419.1 - 1.5e-05 25.5 0.0 4.4e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Rap1, DNA-binding Atx10homo_assoc PF09759.9 GAM34420.1 - 4.1e-32 110.1 0.3 1.2e-31 108.7 0.3 1.8 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain DHHC PF01529.20 GAM34420.1 - 0.055 13.6 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase zf-RING_2 PF13639.6 GAM34421.1 - 1.3e-08 35.0 2.3 2e-08 34.4 2.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAM34421.1 - 8e-06 26.0 2.8 0.00012 22.2 2.8 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAM34421.1 - 0.001 19.1 6.6 0.0017 18.3 6.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GAM34421.1 - 0.0021 18.1 0.5 0.0032 17.5 0.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 GAM34421.1 - 0.014 15.2 5.0 0.13 12.1 4.7 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAM34421.1 - 0.036 13.8 1.1 0.064 13.0 1.1 1.4 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 GAM34421.1 - 0.079 12.8 1.2 0.85 9.5 1.2 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM34421.1 - 0.24 11.3 2.6 3.5 7.6 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Putative_PNPOx PF01243.20 GAM34422.1 - 1.4e-06 28.4 0.0 8.6e-05 22.7 0.0 3.1 3 1 0 3 3 3 1 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 GAM34422.1 - 0.0099 16.2 0.0 0.068 13.5 0.0 2.3 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain Methyltransf_2 PF00891.18 GAM34423.1 - 1.6e-11 43.9 0.0 2.7e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MARVEL PF01284.23 GAM34424.1 - 0.00012 22.1 17.4 0.00015 21.8 16.3 1.6 1 1 1 2 2 2 2 Membrane-associating domain NTP_transferase PF00483.23 GAM34425.1 - 8.7e-32 110.6 0.0 1.3e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 GAM34425.1 - 8.3e-09 34.8 5.3 2.9e-05 23.6 0.0 3.6 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 GAM34425.1 - 2.3e-07 31.3 0.0 3.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 GAM34425.1 - 0.0095 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Fucokinase PF07959.12 GAM34425.1 - 0.043 12.8 0.1 7.5 5.4 0.0 2.1 2 0 0 2 2 2 0 L-fucokinase Dynamin_N PF00350.23 GAM34426.1 - 2.4e-24 86.3 0.1 1.4e-23 83.8 0.0 2.3 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 GAM34426.1 - 9.1e-24 84.2 0.6 1.8e-21 76.6 0.0 2.2 1 1 1 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 GAM34426.1 - 0.0013 18.7 0.0 0.019 15.1 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 GAM34426.1 - 0.0018 18.4 0.7 0.0085 16.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain IIGP PF05049.13 GAM34426.1 - 0.0045 16.1 0.0 0.49 9.4 0.0 2.5 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 GAM34426.1 - 0.033 14.6 0.1 0.67 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Lyase_8_N PF08124.11 GAM34426.1 - 0.037 13.0 0.1 0.087 11.7 0.1 1.7 1 1 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain AAA_15 PF13175.6 GAM34426.1 - 0.041 13.6 3.7 3.4 7.3 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 GAM34426.1 - 0.06 13.6 0.0 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase tRNA-synt_2 PF00152.20 GAM34427.1 - 8.4e-78 261.6 0.6 1.1e-77 261.2 0.6 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAM34427.1 - 2.1e-11 43.7 0.0 6.3e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAM34427.1 - 4.8e-06 26.2 0.1 0.054 13.0 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) COX15-CtaA PF02628.15 GAM34428.1 - 1.7e-115 385.6 3.2 2.1e-115 385.3 3.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Fumarate_red_C PF02300.17 GAM34428.1 - 0.099 12.7 0.8 9.2 6.4 0.1 3.1 3 0 0 3 3 3 0 Fumarate reductase subunit C PQ-loop PF04193.14 GAM34428.1 - 0.25 11.1 2.1 16 5.4 0.1 2.9 2 0 0 2 2 2 0 PQ loop repeat zf-C3HC PF07967.13 GAM34429.1 - 9.3e-41 139.0 0.1 2.7e-36 124.5 0.1 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 GAM34429.1 - 1.1e-27 96.0 0.0 5.2e-27 93.8 0.0 2.1 2 0 0 2 2 2 1 Rsm1-like Pox_MCEL PF03291.16 GAM34430.1 - 8.5e-67 225.6 0.0 6.2e-64 216.2 0.0 3.3 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.12 GAM34430.1 - 2.3e-10 41.1 0.0 9.4e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM34430.1 - 1.3e-09 38.7 0.0 0.0012 19.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 GAM34430.1 - 2e-06 28.4 0.0 0.023 15.3 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 GAM34430.1 - 4.1e-05 23.4 0.0 0.037 13.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 GAM34430.1 - 0.00067 18.9 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 GAM34430.1 - 0.0021 17.9 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAM34430.1 - 0.14 11.6 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase Raftlin PF15250.6 GAM34430.1 - 0.39 9.4 11.1 3 6.5 0.0 2.3 2 0 0 2 2 2 0 Raftlin zf-Nse PF11789.8 GAM34431.1 - 2.1e-20 72.3 0.1 4.1e-20 71.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 GAM34431.1 - 0.0017 18.3 0.0 0.013 15.5 0.0 2.2 1 1 1 2 2 2 1 RING-type zinc-finger U-box PF04564.15 GAM34431.1 - 0.041 14.1 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 U-box domain zf-MIZ PF02891.20 GAM34431.1 - 0.044 13.6 2.6 0.075 12.8 0.1 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.6 GAM34431.1 - 0.046 13.6 0.0 0.046 13.6 0.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.27 GAM34432.1 - 2.2e-53 178.1 4.0 5.7e-18 64.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tir_receptor_N PF07490.11 GAM34432.1 - 0.12 12.2 0.6 0.27 11.1 0.6 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus PEPCK_ATP PF01293.20 GAM34433.1 - 1.9e-217 722.5 0.0 2.3e-217 722.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 GAM34433.1 - 0.13 12.4 0.2 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAM34433.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Asparaginase_2 PF01112.18 GAM34434.1 - 4.8e-47 160.5 13.3 3.7e-46 157.6 13.3 2.0 1 1 0 1 1 1 1 Asparaginase Actin PF00022.19 GAM34435.1 - 3.4e-88 296.0 0.0 1.2e-85 287.7 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 GAM34435.1 - 0.038 12.8 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein tRNA_U5-meth_tr PF05958.11 GAM34436.1 - 8.6e-12 44.7 0.0 2.4e-05 23.5 0.0 2.6 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 GAM34436.1 - 0.00053 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 GAM34436.1 - 0.00056 19.5 0.0 0.00099 18.7 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 GAM34436.1 - 0.0024 17.3 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAM34436.1 - 0.0041 17.8 0.0 0.012 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAM34436.1 - 0.014 15.1 0.0 0.046 13.5 0.0 1.8 2 0 0 2 2 2 0 Met-10+ like-protein MTS PF05175.14 GAM34436.1 - 0.071 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ribosomal_S5_C PF03719.15 GAM34437.1 - 1.7e-24 85.0 0.0 2.9e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 GAM34437.1 - 3.1e-17 62.3 0.4 1.3e-16 60.3 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain RPA43_OB PF17875.1 GAM34437.1 - 0.13 12.9 0.1 0.26 11.9 0.1 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DASH_Dad3 PF08656.10 GAM34438.1 - 7.2e-27 93.3 1.2 9.2e-27 92.9 1.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Pkinase PF00069.25 GAM34439.1 - 2.6e-74 249.9 0.0 3.6e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM34439.1 - 6.9e-30 104.2 0.0 1.7e-21 76.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAM34439.1 - 9.7e-07 28.4 0.1 0.46 9.7 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 GAM34439.1 - 0.0098 14.7 0.1 0.053 12.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAM34439.1 - 0.044 13.1 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM34439.1 - 0.18 11.7 0.0 2.9 7.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family ASD2 PF08687.11 GAM34440.1 - 0.13 11.8 0.2 0.13 11.8 0.2 2.6 2 1 0 3 3 3 0 Apx/Shroom domain ASD2 Presenilin PF01080.17 GAM34440.1 - 2.4 6.8 4.5 3.5 6.3 4.5 1.1 1 0 0 1 1 1 0 Presenilin His_Phos_2 PF00328.22 GAM34441.1 - 2e-12 47.2 0.1 3.4e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.25 GAM34442.1 - 6.7e-20 71.4 0.0 5.9e-18 65.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 GAM34442.1 - 2e-07 31.1 0.0 3.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 GAM34442.1 - 5.4e-07 29.4 0.0 7.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_28 PF00295.17 GAM34443.1 - 3.7e-46 157.7 8.9 6.6e-46 156.9 8.8 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 DUF1989 PF09347.10 GAM34444.1 - 7e-51 172.2 0.0 9.3e-51 171.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) AA_permease_2 PF13520.6 GAM34445.1 - 4.5e-45 154.2 40.5 5.5e-45 154.0 40.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM34445.1 - 3.6e-17 62.1 37.5 4.8e-17 61.7 37.5 1.1 1 0 0 1 1 1 1 Amino acid permease Glyoxalase_4 PF13669.6 GAM34446.1 - 9.2e-20 71.0 0.0 1.6e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Polysacc_deac_1 PF01522.21 GAM34447.1 - 4.2e-18 65.4 0.0 7.7e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 GAM34447.1 - 2.1e-05 24.3 0.0 7.2e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 GAM34447.1 - 0.0089 14.4 0.0 0.013 13.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) Fungal_trans_2 PF11951.8 GAM34448.1 - 1e-48 166.1 1.1 1.3e-48 165.8 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM34448.1 - 2e-10 40.6 4.6 3.9e-10 39.7 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.22 GAM34449.1 - 8.7e-41 140.0 0.0 1e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase adh_short PF00106.25 GAM34451.1 - 3.8e-24 85.2 0.1 8e-20 71.1 0.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM34451.1 - 2.1e-11 43.8 0.0 1.6e-08 34.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM34451.1 - 2.3e-08 34.1 0.3 4.1e-08 33.3 0.3 1.4 1 0 0 1 1 1 1 KR domain Pectinesterase PF01095.19 GAM34452.1 - 1.8e-53 181.2 10.2 2.3e-53 180.9 10.2 1.0 1 0 0 1 1 1 1 Pectinesterase AA_permease_2 PF13520.6 GAM34453.1 - 3.4e-55 187.6 48.1 4.5e-55 187.2 48.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM34453.1 - 3.4e-27 95.2 43.6 4.3e-27 94.8 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease SLATT_5 PF18160.1 GAM34453.1 - 7.6 5.8 6.2 2.4 7.5 2.2 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 CN_hydrolase PF00795.22 GAM34454.1 - 2.9e-46 157.9 0.0 3.7e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TRF PF08558.10 GAM34456.1 - 4.7e-84 281.7 2.5 6.7e-84 281.2 2.5 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 GAM34456.1 - 0.00055 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain TFIID_30kDa PF03540.13 GAM34457.1 - 4.4e-22 77.8 0.1 7.1e-22 77.1 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit SWI-SNF_Ssr4 PF08549.10 GAM34457.1 - 3.1 6.3 4.5 3.7 6.1 4.5 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) FoP_duplication PF13865.6 GAM34457.1 - 6.2 7.5 10.6 85 3.8 10.6 2.3 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 IPK PF03770.16 GAM34458.1 - 5.1e-60 202.7 0.0 7.3e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.10 GAM34459.1 - 7.8e-128 427.1 0.0 1.1e-127 426.6 0.0 1.2 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Tim54 PF11711.8 GAM34459.1 - 0.057 12.2 4.9 0.2 10.4 4.6 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Rrn6 PF10214.9 GAM34459.1 - 0.15 10.5 2.9 0.22 10.0 2.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor ADH_zinc_N PF00107.26 GAM34460.1 - 7.1e-27 94.0 0.0 1.2e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM34460.1 - 3.3e-22 80.0 0.0 6.9e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM34460.1 - 1e-07 31.8 0.0 6.2e-07 29.3 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAM34460.1 - 0.0052 16.7 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Cpn10 PF00166.21 GAM34460.1 - 0.011 15.7 0.1 0.15 12.1 0.0 2.4 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit adh_short PF00106.25 GAM34460.1 - 0.089 12.2 0.5 0.13 11.7 0.5 1.2 1 0 0 1 1 1 0 short chain dehydrogenase ABC_tran PF00005.27 GAM34461.1 - 1e-44 152.4 0.0 6.9e-21 75.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAM34461.1 - 8.1e-21 74.9 28.5 9.8e-20 71.3 5.0 5.6 3 2 1 4 4 4 2 ABC transporter transmembrane region AAA_21 PF13304.6 GAM34461.1 - 7.4e-08 32.6 1.1 0.32 10.7 0.0 3.6 4 0 0 4 4 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM34461.1 - 5.1e-07 29.3 2.5 0.012 15.0 0.1 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM34461.1 - 1.1e-06 28.3 0.0 0.084 12.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 GAM34461.1 - 2.7e-06 26.7 0.1 0.015 14.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 GAM34461.1 - 1.2e-05 25.7 0.0 0.0038 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAM34461.1 - 3.4e-05 24.1 0.0 0.21 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAM34461.1 - 0.00012 22.0 0.1 0.6 10.0 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 GAM34461.1 - 0.00024 20.7 1.6 1.8 8.1 0.4 4.0 3 1 0 3 3 3 2 AAA domain NB-ARC PF00931.22 GAM34461.1 - 0.00028 20.1 0.9 0.038 13.2 0.2 3.0 2 1 0 2 2 2 1 NB-ARC domain DUF87 PF01935.17 GAM34461.1 - 0.00035 20.7 0.1 0.00066 19.8 0.1 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_23 PF13476.6 GAM34461.1 - 0.00042 20.9 0.5 0.76 10.2 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAM34461.1 - 0.00049 20.6 0.0 0.92 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAM34461.1 - 0.00061 19.4 0.1 1.2 8.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 GAM34461.1 - 0.00078 19.8 0.1 1.4 9.3 0.0 3.1 3 0 0 3 3 2 1 RNA helicase MMR_HSR1 PF01926.23 GAM34461.1 - 0.0037 17.3 0.1 0.12 12.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 GAM34461.1 - 0.012 15.5 0.2 3.9 7.3 0.0 2.4 2 0 0 2 2 2 0 NTPase RepL PF05732.11 GAM34461.1 - 0.012 15.0 0.8 0.026 13.9 0.8 1.5 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) AAA_15 PF13175.6 GAM34461.1 - 0.014 15.1 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 GAM34461.1 - 0.015 15.3 0.1 8.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 GAM34461.1 - 0.015 15.2 0.3 2.6 7.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 GAM34461.1 - 0.019 15.4 0.1 0.13 12.7 0.1 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAM34461.1 - 0.034 13.8 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 GAM34461.1 - 0.035 14.3 0.0 4 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAM34461.1 - 0.049 13.4 0.2 26 4.5 0.0 3.3 4 0 0 4 4 3 0 IstB-like ATP binding protein DEAD PF00270.29 GAM34461.1 - 0.054 13.3 0.1 0.37 10.5 0.0 2.3 2 1 0 2 2 2 0 DEAD/DEAH box helicase cobW PF02492.19 GAM34461.1 - 0.13 11.8 0.7 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 GAM34461.1 - 0.13 11.6 0.6 0.24 10.7 0.0 1.6 2 0 0 2 2 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 GAM34461.1 - 0.15 11.7 0.0 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAM34461.1 - 0.19 11.6 0.1 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 GAM34461.1 - 0.2 11.7 0.2 27 4.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CLP1_N PF16573.5 GAM34463.1 - 5.6e-31 106.6 0.0 4.2e-30 103.8 0.0 2.1 1 1 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 GAM34463.1 - 1e-28 100.4 0.0 5e-28 98.2 0.0 2.0 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 GAM34463.1 - 2.2e-25 89.3 0.0 9.8e-25 87.3 0.0 2.0 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 GAM34463.1 - 0.00014 21.7 0.0 0.00032 20.6 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 GAM34463.1 - 0.0052 16.9 0.1 0.023 14.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 GAM34463.1 - 0.024 15.1 0.0 0.054 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter CEL_III_C PF18054.1 GAM34463.1 - 0.066 13.3 0.5 0.13 12.3 0.2 1.6 1 1 0 1 1 1 0 CEL-III C-terminal SRPRB PF09439.10 GAM34463.1 - 0.084 12.3 0.6 0.71 9.3 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 GAM34463.1 - 0.092 12.5 0.1 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 GAM34463.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 GAM34463.1 - 0.2 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_35 PF14516.6 GAM34463.1 - 0.21 10.4 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain KilA-N PF04383.13 GAM34464.1 - 2.1e-05 24.3 0.8 0.00013 21.7 0.0 2.5 2 1 1 3 3 3 1 KilA-N domain Mitofilin PF09731.9 GAM34464.1 - 0.016 14.0 21.2 0.027 13.4 21.2 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SCIMP PF15050.6 GAM34464.1 - 0.15 12.5 2.9 0.48 10.9 2.7 2.0 1 1 0 1 1 1 0 SCIMP protein Rho_GDI PF02115.17 GAM34465.1 - 7.6e-62 208.5 0.1 8.3e-62 208.4 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor CopC PF04234.12 GAM34465.1 - 0.042 14.9 0.0 0.072 14.1 0.0 1.4 1 0 0 1 1 1 0 CopC domain Metallophos PF00149.28 GAM34466.1 - 2.7e-37 129.3 0.6 4.4e-37 128.6 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAM34466.1 - 0.0049 17.3 0.4 0.013 15.9 0.4 1.8 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 GAM34466.1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Adaptin_N PF01602.20 GAM34468.1 - 1.8e-103 346.9 0.0 1.4e-102 344.0 0.0 2.0 2 0 0 2 2 2 1 Adaptin N terminal region Nuf2 PF03800.14 GAM34468.1 - 4.3e-43 146.8 0.1 9.4e-43 145.7 0.1 1.6 1 0 0 1 1 1 1 Nuf2 family Cnd1 PF12717.7 GAM34468.1 - 3.4e-14 53.2 0.1 5.5e-11 42.8 0.0 3.6 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM34468.1 - 2.7e-08 34.1 0.6 0.00051 20.4 0.0 4.1 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 GAM34468.1 - 3.7e-05 23.6 0.0 0.14 12.5 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat VHS PF00790.19 GAM34468.1 - 0.015 15.2 0.4 35 4.2 0.0 3.7 3 0 0 3 3 3 0 VHS domain DivIC PF04977.15 GAM34468.1 - 0.054 13.3 3.3 0.21 11.4 3.3 2.1 1 0 0 1 1 1 0 Septum formation initiator Cnd3 PF12719.7 GAM34468.1 - 0.33 10.1 0.0 0.33 10.1 0.0 2.3 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.7 GAM34468.1 - 0.45 10.9 2.8 3.8 7.9 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Sporozoite_P67 PF05642.11 GAM34468.1 - 0.52 8.3 10.1 0.91 7.5 10.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CRISPR_Cse2 PF09485.10 GAM34468.1 - 2.1 8.8 8.2 29 5.2 4.3 3.7 3 1 0 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) IF-2B PF01008.17 GAM34469.1 - 4e-48 164.0 0.0 7.4e-48 163.2 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family ADH_zinc_N PF00107.26 GAM34470.1 - 1.6e-10 41.0 0.0 4.8e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM34470.1 - 1.6e-07 31.2 0.0 2.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM34470.1 - 0.032 15.3 0.4 0.068 14.2 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF1681 PF07933.14 GAM34471.1 - 7.8e-54 181.4 0.0 9.9e-54 181.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Thioredoxin PF00085.20 GAM34473.1 - 1.2e-28 99.1 0.2 1.4e-28 98.9 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAM34473.1 - 1e-06 29.2 0.1 2e-06 28.2 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAM34473.1 - 1.6e-05 25.2 0.0 5.7e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 GAM34473.1 - 6.6e-05 22.7 0.0 6.7e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 GAM34473.1 - 0.00014 21.3 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 GAM34473.1 - 0.00052 19.7 0.1 0.097 12.4 0.1 2.0 1 1 1 2 2 2 2 Redoxin Thioredoxin_7 PF13899.6 GAM34473.1 - 0.0035 17.5 0.2 0.0063 16.7 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 GAM34473.1 - 0.0074 16.2 0.0 0.024 14.6 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 GAM34473.1 - 0.01 16.0 0.1 0.019 15.2 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin HyaE PF07449.11 GAM34473.1 - 0.041 13.8 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 GAM34473.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin MFS_1 PF07690.16 GAM34474.1 - 2.3e-41 141.9 42.5 6e-41 140.5 41.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM34474.1 - 1.1e-08 34.4 33.1 1.2e-08 34.3 12.3 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter Acetyltransf_7 PF13508.7 GAM34475.1 - 4.2e-08 33.5 0.0 6.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM34475.1 - 3.2e-07 30.6 0.0 1.1e-06 28.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM34475.1 - 2e-05 24.5 0.0 0.00014 21.8 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM34475.1 - 0.0004 20.3 0.0 0.0037 17.2 0.0 2.1 1 1 0 1 1 1 1 FR47-like protein DUF2735 PF10931.8 GAM34475.1 - 0.098 13.4 0.1 15 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2735) AMP-binding PF00501.28 GAM34476.1 - 4e-39 134.4 0.0 5.6e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 GAM34476.1 - 5.7e-11 42.2 0.6 5.7e-11 42.2 0.6 1.9 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 GAM34476.1 - 0.0032 18.4 0.1 0.015 16.3 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain VGLL4 PF15245.6 GAM34477.1 - 0.21 11.6 3.4 0.34 10.9 3.4 1.4 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Presenilin PF01080.17 GAM34477.1 - 0.84 8.3 4.8 0.81 8.4 4.8 1.1 1 0 0 1 1 1 0 Presenilin Pkinase_fungal PF17667.1 GAM34478.1 - 4e-111 371.7 2.3 1.9e-65 221.2 0.1 2.2 1 1 1 2 2 2 2 Fungal protein kinase DAO PF01266.24 GAM34478.1 - 7.9e-31 107.9 0.2 1.6e-30 106.9 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pkinase PF00069.25 GAM34478.1 - 2.6e-05 23.7 0.0 5.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM34478.1 - 0.0021 17.4 0.1 0.0039 16.5 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POTRA_TamA_1 PF17243.2 GAM34478.1 - 0.0048 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 POTRA domain TamA domain 1 APH PF01636.23 GAM34478.1 - 0.0093 15.9 0.1 0.099 12.6 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family MRP-S35 PF10246.9 GAM34478.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 ABC_tran PF00005.27 GAM34479.1 - 7.1e-51 172.3 0.0 8e-30 104.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 GAM34479.1 - 6e-39 134.3 28.8 2.7e-25 89.6 7.5 4.1 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 GAM34479.1 - 1.2e-08 34.7 0.1 0.00029 20.3 0.0 3.9 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GAM34479.1 - 0.0002 21.4 0.1 0.12 12.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM34479.1 - 0.00028 20.8 0.0 0.17 11.7 0.0 2.8 3 0 0 3 3 2 1 RsgA GTPase T2SSE PF00437.20 GAM34479.1 - 0.00032 19.9 0.0 0.045 12.8 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 GAM34479.1 - 0.001 19.5 2.4 1.2 9.5 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 GAM34479.1 - 0.0019 17.9 1.0 3.8 7.3 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_25 PF13481.6 GAM34479.1 - 0.0055 16.3 0.2 1.6 8.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 GAM34479.1 - 0.0094 16.2 2.6 4.8 7.5 0.1 3.5 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 GAM34479.1 - 0.0095 15.8 0.1 14 5.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2075 PF09848.9 GAM34479.1 - 0.016 14.5 0.1 0.31 10.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 GAM34479.1 - 0.019 14.7 0.2 3.4 7.4 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_23 PF13476.6 GAM34479.1 - 0.032 14.7 0.2 3.1 8.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 GAM34479.1 - 0.048 13.4 0.0 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 GAM34479.1 - 0.054 13.6 3.4 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 GAM34479.1 - 0.075 12.7 0.0 6.1 6.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 GAM34479.1 - 0.094 11.7 0.0 0.24 10.3 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 GAM34479.1 - 0.19 11.8 0.5 15 5.7 0.4 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPgrasp_N PF18130.1 GAM34480.1 - 8.6e-16 58.3 0.0 2e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 GAM34480.1 - 5.1e-10 39.2 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAM34480.1 - 7.6e-08 32.1 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus GARS_A PF01071.19 GAM34480.1 - 3.2e-05 23.8 0.0 5.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 GAM34480.1 - 0.0011 18.5 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 GAM34480.1 - 0.016 15.3 0.0 0.097 12.7 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain Zn_clus PF00172.18 GAM34481.1 - 1.6e-08 34.5 6.7 3.3e-08 33.5 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM34481.1 - 0.0013 17.8 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.13 GAM34482.1 - 5.8e-16 58.8 0.0 1.4e-15 57.5 0.0 1.6 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 GAM34482.1 - 1.3e-13 51.3 0.0 1.9e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAM34482.1 - 5.2e-08 33.2 0.1 1.2e-07 32.0 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 GAM34482.1 - 1.8e-05 24.3 0.3 3.1e-05 23.6 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 GAM34482.1 - 0.00023 21.6 0.1 0.00043 20.7 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAM34482.1 - 0.0016 18.6 0.6 0.0033 17.5 0.1 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 GAM34482.1 - 0.0026 18.6 0.2 0.0052 17.6 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold KR PF08659.10 GAM34482.1 - 0.01 15.7 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 0 KR domain 3HCDH_N PF02737.18 GAM34482.1 - 0.021 14.7 0.2 0.041 13.8 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 GAM34482.1 - 0.036 14.1 0.1 0.067 13.3 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 GAM34482.1 - 0.037 13.5 1.7 0.082 12.4 1.5 1.8 1 1 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.20 GAM34482.1 - 0.045 13.8 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 GAM34482.1 - 0.069 12.8 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 GAM34482.1 - 0.072 13.7 0.1 0.21 12.1 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GAM34482.1 - 0.086 13.1 0.4 0.26 11.5 0.4 1.9 1 1 0 1 1 1 0 TrkA-N domain DUF2391 PF09622.10 GAM34482.1 - 0.093 12.0 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) GDP_Man_Dehyd PF16363.5 GAM34482.1 - 0.12 11.7 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CoA_binding PF02629.19 GAM34482.1 - 0.19 12.5 1.3 0.5 11.1 1.3 1.8 1 0 0 1 1 1 0 CoA binding domain VIT1 PF01988.19 GAM34483.1 - 5.3e-65 219.3 1.7 3.3e-64 216.7 3.3 1.5 2 0 0 2 2 2 1 VIT family MMS19_N PF14500.6 GAM34484.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II OTU PF02338.19 GAM34485.1 - 2.1e-08 34.7 0.0 3.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.16 GAM34485.1 - 0.0023 17.6 0.1 0.011 15.4 0.1 2.0 2 0 0 2 2 2 1 CUE domain PGA_cap PF09587.10 GAM34486.1 - 2.4e-57 194.3 0.0 3.9e-57 193.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap GATA PF00320.27 GAM34487.1 - 1.5e-28 98.0 19.5 1.3e-14 53.4 6.8 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 GAM34487.1 - 2e-06 27.2 3.7 0.0013 18.2 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 GAM34487.1 - 1.8e-05 24.7 2.2 0.072 13.2 0.2 2.8 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 GAM34487.1 - 0.00089 19.4 4.8 0.071 13.3 0.2 2.7 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 GAM34487.1 - 0.012 15.6 5.5 0.31 11.0 0.5 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.7 GAM34487.1 - 0.02 14.9 11.1 14 5.8 11.2 3.1 1 1 0 1 1 1 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 GAM34487.1 - 0.035 14.0 4.0 2.9 7.8 0.2 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 ArfGap PF01412.18 GAM34487.1 - 0.08 13.0 3.7 0.54 10.4 0.2 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Rubredoxin_2 PF18073.1 GAM34487.1 - 1.3 8.8 9.5 16 5.3 0.2 4.5 4 0 0 4 4 4 0 Rubredoxin metal binding domain Nudix_N_2 PF14803.6 GAM34487.1 - 5.4 7.0 11.6 6.9 6.7 2.5 3.3 2 1 1 3 3 3 0 Nudix N-terminal Fungal_trans PF04082.18 GAM34488.1 - 1.1e-14 54.1 0.1 4.9e-14 52.0 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.13 GAM34489.1 - 3.4e-21 75.9 0.3 6.1e-21 75.0 0.3 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM34489.1 - 1.1e-12 48.2 0.1 3.6e-12 46.6 0.0 1.8 1 1 1 2 2 2 1 NAD(P)H-binding Ferritin PF00210.24 GAM34489.1 - 9.5e-08 32.1 0.0 3.2e-07 30.4 0.0 1.9 2 1 1 3 3 3 1 Ferritin-like domain Kinase-PPPase PF03618.14 GAM34489.1 - 0.0077 16.0 0.2 0.015 15.1 0.2 1.4 1 0 0 1 1 1 1 Kinase/pyrophosphorylase PHA_synth_III_E PF09712.10 GAM34489.1 - 0.019 14.1 0.1 0.057 12.5 0.1 1.7 2 0 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Epimerase PF01370.21 GAM34489.1 - 0.068 12.6 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM34489.1 - 0.12 11.4 0.2 0.22 10.5 0.2 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Rnk_N PF14760.6 GAM34489.1 - 0.23 12.0 0.8 1.4 9.5 0.3 2.4 2 0 0 2 2 2 0 Rnk N-terminus DapB_N PF01113.20 GAM34489.1 - 0.81 9.8 2.8 3.4 7.8 0.1 2.9 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Cu-oxidase_2 PF07731.14 GAM34491.1 - 1.7e-40 137.9 1.8 1.7e-40 137.9 1.8 2.7 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAM34491.1 - 5.2e-38 129.7 4.2 5.2e-38 129.7 4.2 3.3 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 GAM34491.1 - 2.8e-37 128.3 7.1 3.1e-36 124.9 0.9 3.1 3 0 0 3 3 3 2 Multicopper oxidase DUF756 PF05506.12 GAM34491.1 - 0.084 13.8 3.0 2.4 9.1 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF756) APH PF01636.23 GAM34492.1 - 6.5e-13 49.2 0.0 1.2e-12 48.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM34492.1 - 7.4e-09 35.5 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kelch_1 PF01344.25 GAM34493.1 - 4.3e-06 26.2 0.1 4.3e-06 26.2 0.1 5.1 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 GAM34493.1 - 7.7e-05 22.8 10.5 0.0019 18.4 0.1 5.5 6 0 0 6 6 6 1 Kelch motif Kelch_3 PF13415.6 GAM34493.1 - 0.0012 19.1 17.3 0.0024 18.1 1.2 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.6 GAM34493.1 - 0.0022 18.0 1.3 0.0022 18.0 1.3 4.9 5 1 0 5 5 5 1 Galactose oxidase, central domain MscS_TM PF12794.7 GAM34493.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 SKG6 PF08693.10 GAM34493.1 - 0.22 10.9 1.5 0.44 10.0 1.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_5 PF13854.6 GAM34493.1 - 0.28 11.2 0.1 0.28 11.2 0.1 4.8 6 0 0 6 6 6 0 Kelch motif Kelch_2 PF07646.15 GAM34493.1 - 1.9 8.6 8.3 5.7 7.1 0.1 5.0 6 0 0 6 6 6 0 Kelch motif COPI_assoc PF08507.10 GAM34495.1 - 6e-31 107.2 6.4 6.5e-31 107.1 6.4 1.0 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.9 GAM34495.1 - 0.2 12.0 5.3 0.41 11.0 5.3 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P adh_short PF00106.25 GAM34496.1 - 8e-54 182.1 0.1 1.1e-53 181.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM34496.1 - 1.9e-36 125.8 0.1 2.6e-36 125.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM34496.1 - 9.5e-13 48.4 0.0 1.5e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM34496.1 - 0.00022 20.5 0.3 0.00039 19.6 0.3 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 GAM34496.1 - 0.0004 20.6 0.1 0.00082 19.6 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAM34496.1 - 0.023 14.7 0.8 0.085 12.9 0.2 2.1 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Toprim_4 PF13662.6 GAM34496.1 - 0.061 13.8 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Toprim domain Ras PF00071.22 GAM34497.1 - 7.2e-60 201.3 0.2 8.4e-60 201.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM34497.1 - 1.4e-20 73.7 0.0 2.1e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM34497.1 - 9.6e-09 34.9 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM34497.1 - 1.2e-06 28.2 0.2 6.7e-06 25.8 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAM34497.1 - 5.7e-05 23.1 0.7 0.24 11.3 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM34497.1 - 0.0019 18.2 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 GAM34497.1 - 0.007 16.4 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 GAM34497.1 - 0.01 15.3 0.0 0.019 14.5 0.0 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B Ser_hydrolase PF06821.13 GAM34497.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase IstB_IS21 PF01695.17 GAM34497.1 - 0.17 11.6 0.8 2.4 7.9 0.2 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 GAM34497.1 - 0.49 10.1 2.2 4.1 7.1 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MoCF_biosynth PF00994.24 GAM34498.1 - 2.6e-33 114.7 0.0 4.3e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 GAM34498.1 - 0.092 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain Cofilin_ADF PF00241.20 GAM34499.1 - 2.5e-19 69.3 0.0 3.1e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1887 PF09002.11 GAM34499.1 - 0.0089 14.7 0.0 0.12 11.0 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF1887) MFS_1 PF07690.16 GAM34500.1 - 2.7e-15 56.2 40.4 3.7e-15 55.7 38.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAM34500.1 - 1.4e-06 28.1 4.7 1.4e-06 28.1 4.7 2.4 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 GAM34500.1 - 3.3e-06 26.3 11.5 3.3e-06 26.3 11.5 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter PUCC PF03209.15 GAM34500.1 - 0.00095 18.3 3.8 0.0019 17.2 2.9 2.0 1 1 1 2 2 2 1 PUCC protein DAO PF01266.24 GAM34501.1 - 3.6e-45 155.1 0.1 4.3e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAM34501.1 - 1.5e-05 24.4 0.0 2.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 GAM34501.1 - 1.5e-05 24.4 0.0 0.04 13.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM34501.1 - 1.5e-05 25.0 0.2 0.0035 17.3 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAM34501.1 - 0.00099 19.3 0.3 0.0023 18.1 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM34501.1 - 0.0045 16.3 0.0 0.0071 15.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM34501.1 - 0.011 14.9 1.5 0.011 14.8 0.4 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.6 GAM34501.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Hydrolase PF00702.26 GAM34502.1 - 4.2e-06 27.2 0.0 0.00016 22.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAM34502.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Aldedh PF00171.22 GAM34503.1 - 5.7e-153 509.7 0.0 6.4e-153 509.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DAO PF01266.24 GAM34504.1 - 1.2e-35 123.8 0.7 5.6e-35 121.6 0.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM34504.1 - 0.00039 20.6 0.0 0.0012 19.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM34504.1 - 0.0053 16.0 0.0 0.047 12.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM34504.1 - 0.034 13.4 0.0 0.077 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM34504.1 - 0.04 13.2 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NmrA PF05368.13 GAM34505.1 - 6.2e-29 101.2 0.0 8e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM34505.1 - 5.2e-20 72.1 0.0 6.9e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAM34505.1 - 1.1e-06 28.9 0.0 1.7e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 GAM34505.1 - 0.00026 20.5 0.0 0.00062 19.3 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAM34505.1 - 0.001 18.3 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 GAM34505.1 - 0.0013 17.8 0.0 0.0026 16.8 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 GAM34505.1 - 0.022 14.8 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 GAM34505.1 - 0.1 13.1 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans PF04082.18 GAM34506.1 - 6.9e-12 45.0 3.6 1.1e-11 44.3 3.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_ribbon_17 PF17120.5 GAM34507.1 - 0.00073 19.1 5.0 0.00073 19.1 5.0 2.1 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type DZR PF12773.7 GAM34507.1 - 0.015 15.3 19.0 7.4 6.7 19.0 3.3 1 1 0 1 1 1 0 Double zinc ribbon Rpr2 PF04032.16 GAM34507.1 - 0.066 13.5 0.2 0.066 13.5 0.2 4.0 3 1 1 5 5 5 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF35_N PF12172.8 GAM34507.1 - 0.12 12.2 0.3 0.12 12.2 0.3 3.5 3 1 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) ADK_lid PF05191.14 GAM34507.1 - 5.2 7.1 14.4 6.5 6.8 1.9 3.6 2 1 0 2 2 2 0 Adenylate kinase, active site lid FYVE PF01363.21 GAM34507.1 - 7 6.9 18.6 6.8 6.9 14.9 2.7 2 1 0 2 2 2 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 GAM34507.1 - 8.5 7.2 19.9 6.4 7.6 7.5 3.2 2 2 0 2 2 2 0 zinc-ribbon family Sugar_tr PF00083.24 GAM34508.1 - 5.8e-79 266.1 24.4 6.6e-79 265.9 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM34508.1 - 2.2e-24 86.1 32.2 4e-15 55.6 15.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM34508.1 - 0.00039 19.0 2.8 0.00039 19.0 2.8 2.3 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_43 PF04616.14 GAM34509.1 - 8.1e-75 251.8 0.8 1.1e-74 251.4 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 GAM34509.1 - 1.6e-10 41.0 0.0 3.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Abhydrolase_3 PF07859.13 GAM34510.1 - 1.1e-30 107.1 0.0 1.3e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 GAM34510.1 - 3.1e-08 33.5 0.0 3.7e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAM34510.1 - 5.7e-07 29.2 0.0 2.3e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAM34510.1 - 0.0008 20.1 1.1 0.0019 18.9 1.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 GAM34510.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 GAM34510.1 - 0.017 15.1 0.0 0.038 13.9 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.8 GAM34510.1 - 0.021 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase PF00756.20 GAM34510.1 - 0.043 13.5 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Putative esterase FSH1 PF03959.13 GAM34510.1 - 0.05 13.3 0.0 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) AXE1 PF05448.12 GAM34510.1 - 0.081 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) adh_short PF00106.25 GAM34511.1 - 6.6e-33 113.8 2.0 9.2e-33 113.3 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM34511.1 - 3.7e-23 82.3 1.2 1.1e-22 80.8 1.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM34511.1 - 5.1e-12 46.1 0.3 7.1e-12 45.6 0.3 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM34511.1 - 0.027 13.6 0.1 0.039 13.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 GAM34511.1 - 0.034 13.9 0.3 0.099 12.4 0.3 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DNA_processg_A PF02481.15 GAM34511.1 - 0.051 12.8 0.3 0.085 12.1 0.3 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A ApbA PF02558.16 GAM34511.1 - 0.075 12.7 1.5 0.17 11.6 0.3 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 GAM34511.1 - 0.093 12.8 0.2 0.26 11.4 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.23 GAM34511.1 - 0.14 12.2 1.5 0.22 11.6 1.5 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 GAM34511.1 - 0.24 11.3 1.0 0.43 10.4 1.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GAM34512.1 - 5.2e-09 36.6 0.0 8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 GAM34512.1 - 0.04 13.8 0.0 0.24 11.2 0.0 2.0 1 1 0 1 1 1 0 Rossmann-like domain Fungal_trans PF04082.18 GAM34513.1 - 6.3e-18 64.8 0.1 8.3e-18 64.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM34513.1 - 1e-07 32.0 11.5 1.6e-07 31.3 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4094 PF13334.6 GAM34513.1 - 0.0031 17.9 0.3 0.0082 16.5 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) BST2 PF16716.5 GAM34513.1 - 0.0076 16.8 0.4 0.56 10.8 0.5 2.5 2 0 0 2 2 2 1 Bone marrow stromal antigen 2 Dynamitin PF04912.14 GAM34513.1 - 0.025 13.9 2.8 0.24 10.7 0.4 2.6 3 0 0 3 3 3 0 Dynamitin Tropomyosin_1 PF12718.7 GAM34513.1 - 0.069 13.3 0.9 0.15 12.2 0.9 1.5 1 0 0 1 1 1 0 Tropomyosin like WXG100 PF06013.12 GAM34513.1 - 0.21 11.9 2.1 0.45 10.8 2.1 1.5 1 0 0 1 1 1 0 Proteins of 100 residues with WXG FlxA PF14282.6 GAM34513.1 - 2.4 8.2 7.3 0.49 10.4 3.5 1.8 2 0 0 2 2 2 0 FlxA-like protein NmrA PF05368.13 GAM34514.1 - 1.1e-33 116.7 0.0 1.8e-33 116.0 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM34514.1 - 9.4e-10 38.7 0.0 2.1e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 GAM34514.1 - 1.9e-06 27.5 0.0 2.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM34514.1 - 3.7e-05 22.9 0.0 5.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAM34514.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Guanylate_kin PF00625.21 GAM34514.1 - 0.079 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase SNF2_N PF00176.23 GAM34515.1 - 2e-55 187.9 0.2 2.9e-55 187.4 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM34515.1 - 8.1e-16 58.4 0.0 3.6e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM34515.1 - 2.7e-07 30.8 0.0 9.2e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM34515.1 - 4.3e-07 29.9 0.0 7.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 GAM34515.1 - 0.006 15.8 0.1 0.0099 15.1 0.1 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 GAM34515.1 - 0.073 13.0 22.1 0.24 11.3 10.3 2.9 2 1 1 3 3 3 0 PHD-finger DIOX_N PF14226.6 GAM34516.1 - 1.6e-11 45.0 0.0 2.7e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM34516.1 - 1.8e-11 44.4 0.0 3.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UPF0086 PF01868.16 GAM34517.1 - 7.6e-32 109.1 0.5 1.1e-31 108.5 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 tRNA_int_endo PF01974.17 GAM34518.1 - 3.3e-18 65.5 0.1 3e-17 62.5 0.0 2.0 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain DUF4770 PF15994.5 GAM34518.1 - 0.1 12.8 2.2 0.14 12.4 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Malate_DH PF12434.8 GAM34518.1 - 0.17 12.0 4.4 0.5 10.4 4.4 1.8 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Presenilin PF01080.17 GAM34518.1 - 0.44 9.3 1.6 0.58 8.9 1.6 1.1 1 0 0 1 1 1 0 Presenilin DUF3987 PF13148.6 GAM34518.1 - 0.69 8.9 4.4 0.93 8.4 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Rrn6 PF10214.9 GAM34518.1 - 1.9 6.9 6.0 2.3 6.6 6.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PAXNEB PF05625.11 GAM34519.1 - 9.5e-117 390.3 0.0 1.1e-116 390.0 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RNA_pol_Rpb8 PF03870.15 GAM34520.1 - 1.1e-44 152.0 0.0 1.2e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 SSP160 PF06933.11 GAM34521.1 - 0.28 9.4 5.9 0.31 9.2 5.9 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NUDIX PF00293.28 GAM34522.1 - 4e-14 52.8 0.6 1e-13 51.4 0.1 1.9 2 0 0 2 2 2 1 NUDIX domain DUF4743 PF15916.5 GAM34522.1 - 4.3e-11 42.8 0.0 6.3e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) DUF775 PF05603.12 GAM34523.1 - 8.8e-69 231.0 0.0 9.9e-69 230.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) GATase PF00117.28 GAM34524.1 - 2.6e-11 43.7 0.0 3.4e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 GAM34524.1 - 0.0097 15.5 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.16 GAM34525.1 - 7.9e-43 146.7 46.5 3.6e-42 144.6 45.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM34525.1 - 3.3e-10 39.0 15.2 4.7e-10 38.5 15.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Neurensin PF14927.6 GAM34525.1 - 0.18 11.5 0.7 27 4.5 0.0 3.4 4 0 0 4 4 4 0 Neurensin MFS_3 PF05977.13 GAM34525.1 - 0.23 9.8 15.8 0.0056 15.1 3.1 2.6 2 1 1 3 3 3 0 Transmembrane secretion effector Fungal_trans_2 PF11951.8 GAM34526.1 - 6.7e-08 31.7 8.3 6.2e-07 28.6 8.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM34526.1 - 9.2e-07 28.9 10.0 2.8e-06 27.3 10.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.17 GAM34526.1 - 5.2 6.0 6.8 0.92 8.5 0.0 2.1 2 0 0 2 2 2 0 Clusterin SSP160 PF06933.11 GAM34526.1 - 9.3 4.3 12.7 16 3.5 12.7 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Fungal_trans_2 PF11951.8 GAM34527.1 - 0.00065 18.6 0.2 0.00079 18.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.32 GAM34528.1 - 2.6e-13 50.2 6.4 0.00034 21.3 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM34528.1 - 5.7e-05 23.3 0.1 1.3 9.4 0.0 4.3 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cas_GSU0053 PF09617.10 GAM34528.1 - 0.019 14.9 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) DEAD PF00270.29 GAM34529.1 - 1.3e-42 145.5 0.0 1.9e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM34529.1 - 9e-20 71.1 0.1 4.7e-19 68.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAM34529.1 - 6.5e-18 64.7 0.1 1.4e-17 63.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAM34529.1 - 2.4e-05 24.4 0.0 5.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAM34529.1 - 0.015 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase NBD94 PF16830.5 GAM34530.1 - 0.0014 19.0 0.1 0.0029 18.0 0.1 1.5 1 0 0 1 1 1 1 Nucleotide-Binding Domain 94 of RH DivIVA PF05103.13 GAM34530.1 - 1.5 9.0 5.0 1.1 9.3 0.2 2.2 2 0 0 2 2 2 0 DivIVA protein Pyridox_oxase_2 PF12766.7 GAM34531.1 - 7.1e-29 100.4 0.0 1.5e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 GAM34531.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase GDA1_CD39 PF01150.17 GAM34533.1 - 1.1e-103 347.2 0.0 1.5e-103 346.8 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family LRR_9 PF14580.6 GAM34533.1 - 9.4e-41 139.2 0.0 1.7e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 GAM34533.1 - 1.5e-05 24.6 1.0 3.3e-05 23.6 1.0 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 GAM34533.1 - 0.001 19.4 3.0 0.0058 17.0 2.3 2.4 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) HTH_38 PF13936.6 GAM34533.1 - 0.02 14.6 0.5 0.057 13.2 0.5 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4349 PF14257.6 GAM34533.1 - 0.1 12.0 1.7 0.18 11.3 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) HTH_32 PF13565.6 GAM34533.1 - 0.13 12.9 0.2 1.9 9.2 0.2 2.5 2 0 0 2 2 2 0 Homeodomain-like domain p450 PF00067.22 GAM34534.1 - 4.5e-38 131.2 0.0 5.9e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABM PF03992.16 GAM34535.1 - 5.4e-12 45.6 0.1 6.9e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Ammonium_transp PF00909.21 GAM34536.1 - 9.4e-95 317.6 23.1 7.8e-93 311.3 23.1 2.0 1 1 0 1 1 1 1 Ammonium Transporter Family RTX PF02382.15 GAM34536.1 - 0.44 10.2 2.1 11 5.6 2.0 2.2 2 0 0 2 2 2 0 N-terminal domain in RTX protein p450 PF00067.22 GAM34537.1 - 9.2e-42 143.3 0.0 2.4e-17 62.8 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 Acyltransferase PF01553.21 GAM34538.1 - 2.9e-17 62.5 0.0 5.7e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase PRONE PF03759.13 GAM34538.1 - 0.032 13.1 0.0 0.061 12.1 0.0 1.4 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) Pantoate_ligase PF02569.15 GAM34539.1 - 2.6e-94 315.4 0.0 3.1e-94 315.1 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase ATP-sulfurylase PF01747.17 GAM34539.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 ATP-sulfurylase DASH_Dad2 PF08654.10 GAM34540.1 - 0.052 14.0 0.2 0.2 12.1 0.1 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad2 RSN1_7TM PF02714.15 GAM34542.1 - 1.4e-89 300.1 16.9 1.4e-89 300.1 16.9 2.8 3 0 0 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAM34542.1 - 1.5e-45 154.8 2.9 1.5e-45 154.8 2.9 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAM34542.1 - 6.8e-41 140.4 1.6 1e-40 139.8 1.6 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 GAM34542.1 - 1.4e-32 111.7 0.2 1.4e-32 111.7 0.2 2.5 3 0 0 3 3 3 1 Extracellular tail, of 10TM putative phosphate transporter DUF1192 PF06698.11 GAM34542.1 - 0.28 11.3 2.0 0.62 10.2 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Med12-PQL PF12144.8 GAM34543.1 - 0.054 13.4 1.1 0.96 9.3 0.3 2.3 2 0 0 2 2 2 0 Eukaryotic Mediator 12 catenin-binding domain MCM PF00493.23 GAM34544.1 - 9.1e-101 335.6 0.1 1.5e-100 334.9 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAM34544.1 - 1.3e-38 131.7 0.7 3.3e-38 130.4 0.2 2.0 2 0 0 2 2 2 1 MCM OB domain MCM6_C PF18263.1 GAM34544.1 - 5.4e-33 113.5 1.2 5.4e-33 113.5 1.2 2.8 3 0 0 3 3 3 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 GAM34544.1 - 4.9e-24 84.6 1.1 9.6e-24 83.6 0.5 1.9 2 0 0 2 2 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAM34544.1 - 1.4e-22 80.3 1.7 1.4e-22 80.3 1.7 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAM34544.1 - 5e-06 26.0 0.0 3.3e-05 23.4 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAM34544.1 - 0.0025 17.8 0.0 0.0063 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAM34544.1 - 0.0046 16.8 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GIDA_assoc PF13932.6 GAM34544.1 - 0.0051 17.0 0.4 0.015 15.5 0.4 1.8 1 0 0 1 1 1 1 GidA associated domain Sigma54_activat PF00158.26 GAM34544.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Nuf2 PF03800.14 GAM34544.1 - 0.11 12.7 1.8 0.95 9.6 0.0 2.8 3 0 0 3 3 3 0 Nuf2 family SNF2_N PF00176.23 GAM34545.1 - 1.1e-48 165.8 0.0 2.1e-48 164.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM34545.1 - 9.6e-11 42.0 0.0 2.1e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GAM34545.1 - 0.0051 16.0 0.0 0.0093 15.2 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase She9_MDM33 PF05546.11 GAM34546.1 - 7.9e-88 293.5 7.0 1.2e-87 292.8 7.0 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.20 GAM34546.1 - 0.062 13.0 1.0 0.12 12.1 1.0 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein DUF2524 PF10732.9 GAM34546.1 - 1.4 9.3 6.1 1.4 9.3 2.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) Pmp3 PF01679.17 GAM34547.1 - 7e-19 67.8 10.9 8.8e-19 67.5 10.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SH3_9 PF14604.6 GAM34548.1 - 0.00011 21.9 0.1 0.00023 20.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM34548.1 - 0.00024 20.6 0.2 0.00045 19.8 0.2 1.5 1 0 0 1 1 1 1 SH3 domain CYYR1 PF10873.8 GAM34548.1 - 0.00091 19.7 1.4 0.0021 18.5 0.8 1.9 1 1 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Syndecan PF01034.20 GAM34548.1 - 0.0032 17.4 1.2 0.0063 16.4 1.2 1.4 1 0 0 1 1 1 1 Syndecan domain Adeno_E3_CR2 PF02439.15 GAM34548.1 - 0.029 14.1 0.6 0.057 13.2 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.18 GAM34548.1 - 0.042 14.1 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A DUF4690 PF15756.5 GAM34548.1 - 0.056 14.0 0.2 0.17 12.5 0.2 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Mid2 PF04478.12 GAM34548.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor FAM104 PF15434.6 GAM34548.1 - 0.063 13.8 1.3 1.3 9.6 0.0 3.0 3 1 0 3 3 3 0 Family 104 CbiM PF01891.16 GAM34548.1 - 0.21 11.4 3.2 0.33 10.7 3.2 1.2 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region SnoaL_4 PF13577.6 GAM34549.1 - 1e-06 28.9 0.0 1.6e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Lyase_aromatic PF00221.19 GAM34550.1 - 1.1e-155 518.9 7.2 1.3e-155 518.6 7.2 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase PI3_PI4_kinase PF00454.27 GAM34551.1 - 6.9e-52 176.7 1.1 1.5e-51 175.6 0.1 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 GAM34551.1 - 1.2e-41 142.3 2.2 2.2e-40 138.2 0.2 3.2 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 GAM34551.1 - 3.9e-12 45.8 0.1 1.4e-11 44.0 0.1 2.0 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 GAM34551.1 - 8.7e-05 21.9 3.5 8.7e-05 21.9 3.5 2.0 2 0 0 2 2 2 1 FAT domain Nup192 PF11894.8 GAM34552.1 - 0 1326.6 19.4 0 1326.4 19.4 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF4704 PF15787.5 GAM34552.1 - 0.0019 17.5 0.1 0.047 12.9 0.1 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) Cullin PF00888.22 GAM34553.1 - 6.2e-183 609.8 7.5 8.3e-183 609.3 7.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAM34553.1 - 5.6e-23 80.7 2.9 5.6e-23 80.7 2.9 2.8 4 0 0 4 4 4 1 Cullin protein neddylation domain Dak1 PF02733.17 GAM34554.1 - 5.4e-106 354.0 0.2 7e-106 353.6 0.2 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 GAM34554.1 - 6.8e-45 153.1 2.1 6.8e-45 153.1 2.1 1.7 2 0 0 2 2 2 1 DAK2 domain SNF2_N PF00176.23 GAM34555.1 - 3.7e-69 233.1 0.6 5.8e-69 232.5 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM34555.1 - 3.3e-14 53.2 0.2 1e-13 51.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM34555.1 - 6.3e-10 39.1 0.0 2e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAM34555.1 - 3.6e-08 33.6 0.1 1.5e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PNP_UDP_1 PF01048.20 GAM34555.1 - 1.2e-06 27.9 0.0 2.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Phosphorylase superfamily zf-RING_5 PF14634.6 GAM34555.1 - 0.00018 21.4 5.8 0.00018 21.4 5.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain GATA PF00320.27 GAM34555.1 - 0.0022 17.6 7.1 0.1 12.3 3.0 2.9 2 0 0 2 2 2 2 GATA zinc finger Prok-RING_4 PF14447.6 GAM34555.1 - 0.026 14.4 7.0 0.066 13.1 7.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Herpes_DNAp_acc PF04929.12 GAM34555.1 - 0.094 11.7 0.0 0.64 8.9 0.0 2.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Rep_fac-A_3 PF08661.11 GAM34556.1 - 2.5e-27 95.3 0.0 2.8e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 MFAP1 PF06991.11 GAM34557.1 - 1.3e-66 224.6 29.5 1.3e-66 224.6 29.5 4.2 2 2 2 4 4 4 1 Microfibril-associated/Pre-mRNA processing PARM PF17061.5 GAM34557.1 - 4.1 7.5 8.3 6.7 6.8 8.3 1.3 1 0 0 1 1 1 0 PARM TRAPP PF04051.16 GAM34558.1 - 4e-41 140.1 0.0 5.4e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NAD_kinase PF01513.21 GAM34559.1 - 7.1e-71 238.8 0.0 1.2e-70 238.0 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 GAM34559.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Las1 PF04031.13 GAM34561.1 - 1.5e-46 158.3 0.0 1.7e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Las1-like Aldo_ket_red PF00248.21 GAM34562.1 - 4.1e-65 219.9 0.0 4.5e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LID PF17916.1 GAM34562.1 - 0.008 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 LIM interaction domain (LID) HSP70 PF00012.20 GAM34564.1 - 2.5e-09 35.9 0.0 6e-09 34.6 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAM34564.1 - 0.059 12.2 0.2 0.32 9.8 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein FERM_F1 PF18379.1 GAM34564.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 FERM F1 ubiquitin-like domain DcpS_C PF11969.8 GAM34564.1 - 0.12 12.9 0.0 0.36 11.3 0.0 1.7 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding Pericardin_rpt PF07054.11 GAM34564.1 - 1.6 8.9 4.2 0.33 11.1 0.4 1.8 2 0 0 2 2 2 0 Pericardin like repeat FAM76 PF16046.5 GAM34565.1 - 0.0026 17.2 8.0 0.0047 16.3 8.0 1.4 1 0 0 1 1 1 1 FAM76 protein WD40_alt PF14077.6 GAM34565.1 - 0.0054 16.6 0.1 0.02 14.7 0.1 2.0 1 0 0 1 1 1 1 Alternative WD40 repeat motif Lzipper-MIP1 PF14389.6 GAM34565.1 - 0.036 14.3 1.0 0.13 12.6 0.6 2.2 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 LPP PF04728.13 GAM34565.1 - 0.12 12.8 1.8 0.85 10.1 0.4 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF2937 PF11157.8 GAM34565.1 - 0.26 11.0 2.5 1.1 8.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) SlyX PF04102.12 GAM34565.1 - 0.42 11.3 5.1 0.22 12.2 0.7 2.7 3 0 0 3 3 3 0 SlyX Hid1 PF12722.7 GAM34565.1 - 2.3 6.2 8.7 3.3 5.7 8.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ING PF12998.7 GAM34565.1 - 2.5 8.7 7.7 1.4 9.5 0.3 3.4 3 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF1264 PF06884.11 GAM34566.1 - 1.1e-74 249.7 0.0 1.8e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) HAGH_C PF16123.5 GAM34566.1 - 3.4e-19 69.1 0.0 6.3e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 GAM34566.1 - 6.1e-18 65.5 3.1 2.3e-16 60.4 3.1 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM34566.1 - 0.00097 18.7 2.1 0.0091 15.5 2.1 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Peptidase_S26 PF10502.9 GAM34567.1 - 1.1e-05 25.2 0.0 0.001 18.8 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 GAM34567.1 - 5e-05 23.2 0.1 0.00013 21.9 0.1 1.6 1 0 0 1 1 1 1 Peptidase S24-like PBP PF01161.20 GAM34568.1 - 5.7e-10 39.6 0.0 9.7e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ABC_tran_Xtn PF12848.7 GAM34568.1 - 0.085 12.9 1.0 0.19 11.8 1.0 1.5 1 0 0 1 1 1 0 ABC transporter Ribosomal_L4 PF00573.22 GAM34569.1 - 8.8e-48 162.5 0.0 1.2e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family ECH_2 PF16113.5 GAM34570.1 - 5.5e-133 443.6 0.0 7e-133 443.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAM34570.1 - 7.3e-26 91.0 0.0 6.4e-25 87.9 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Death PF00531.22 GAM34570.1 - 0.027 14.6 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Death domain FliD_C PF07195.12 GAM34570.1 - 0.11 11.9 0.5 0.67 9.3 0.0 2.3 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Peptidase_M24 PF00557.24 GAM34571.1 - 2.3e-45 154.8 0.0 4.8e-45 153.8 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.18 GAM34571.1 - 0.00014 22.5 0.0 0.00026 21.7 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Sulfatase PF00884.23 GAM34572.1 - 1.5e-69 234.7 0.0 1.9e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 GAM34572.1 - 0.071 13.0 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF229 PF02995.17 GAM34572.1 - 0.21 10.1 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sugar_tr PF00083.24 GAM34573.1 - 5.2e-103 345.3 21.4 6e-103 345.1 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM34573.1 - 5.1e-18 65.1 29.2 5.1e-18 65.1 29.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily bZIP_1 PF00170.21 GAM34574.1 - 1.8e-10 40.8 10.2 3.2e-10 40.0 10.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAM34574.1 - 6.6e-06 26.1 8.5 1.4e-05 25.1 8.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAM34574.1 - 0.0071 16.8 5.0 0.017 15.6 5.0 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor NADH_Oxid_Nqo15 PF11497.8 GAM34576.1 - 0.028 14.4 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 SOG2 PF10428.9 GAM34576.1 - 0.64 9.2 8.6 0.92 8.6 8.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CBS PF00571.28 GAM34577.1 - 1.8e-22 79.6 6.4 1.3e-09 38.3 0.1 4.3 4 0 0 4 4 4 4 CBS domain CRAL_TRIO PF00650.20 GAM34578.1 - 1.8e-40 138.3 0.0 2.3e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAM34578.1 - 1.9e-18 66.3 0.1 3.5e-18 65.5 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAM34578.1 - 4.6e-05 23.6 0.0 7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.10 GAM34579.1 - 9.6e-80 268.1 0.0 1.5e-79 267.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 GAM34579.1 - 3.3e-36 124.6 0.0 5.3e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Kinesin PF00225.23 GAM34580.1 - 1.8e-112 375.6 0.0 3.8e-112 374.5 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain IF-2B PF01008.17 GAM34580.1 - 4.3e-73 246.0 0.6 4.3e-73 246.0 0.6 1.9 2 0 0 2 2 2 1 Initiation factor 2 subunit family Microtub_bd PF16796.5 GAM34580.1 - 3.1e-25 88.8 0.7 6.6e-25 87.8 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding Spc7 PF08317.11 GAM34580.1 - 0.048 12.5 11.4 0.033 13.1 9.3 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF87 PF01935.17 GAM34580.1 - 0.24 11.5 4.8 1.7 8.7 0.1 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain FapA PF03961.13 GAM34580.1 - 2.3 6.7 7.8 4.1 5.9 7.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A PUL PF08324.11 GAM34581.1 - 2.4e-64 217.3 0.1 3.1e-64 216.9 0.1 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 GAM34581.1 - 2.2e-39 134.7 0.0 3.7e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 GAM34581.1 - 7.1e-15 54.9 0.0 1.4e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 GAM34581.1 - 0.00066 19.6 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 GAM34581.1 - 0.0032 17.5 0.0 0.0071 16.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 GAM34581.1 - 0.0043 17.5 0.2 0.021 15.3 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 GAM34581.1 - 0.052 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Beta-lactamase PF00144.24 GAM34582.1 - 0.057 12.7 0.1 0.079 12.2 0.1 1.2 1 0 0 1 1 1 0 Beta-lactamase UCH PF00443.29 GAM34583.1 - 6.3e-33 114.3 0.0 1.1e-32 113.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM34583.1 - 0.00058 19.5 0.1 0.004 16.8 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Alb1 PF09135.11 GAM34584.1 - 1.4e-24 86.9 7.0 1.4e-24 86.9 7.0 1.7 1 1 1 2 2 2 1 Alb1 F-protein PF00469.20 GAM34584.1 - 0.29 10.7 3.9 0.4 10.2 3.9 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef ABC_tran_Xtn PF12848.7 GAM34584.1 - 2.3 8.3 13.1 1.4 9.0 8.2 2.6 2 1 1 3 3 3 0 ABC transporter Vps16_N PF04841.13 GAM34585.1 - 2.6e-96 322.9 0.0 3.7e-96 322.4 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 GAM34585.1 - 3.8e-81 272.6 0.0 5.5e-81 272.1 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 GAM34585.1 - 0.0028 17.9 0.0 3.8 7.9 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_1 PF00561.20 GAM34586.1 - 4e-24 85.6 0.0 4.6e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM34586.1 - 9e-10 38.2 0.0 1.3e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM34586.1 - 1.2e-07 32.6 0.0 1.5e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 GAM34586.1 - 0.059 12.1 0.0 0.091 11.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family Peptidase_S28 PF05577.12 GAM34586.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Beta_elim_lyase PF01212.21 GAM34587.1 - 2e-58 198.0 0.0 2.7e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GAM34587.1 - 6.5e-05 22.3 0.0 0.00013 21.3 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAM34587.1 - 0.1 11.1 0.0 0.48 8.9 0.0 1.9 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme FHA PF00498.26 GAM34588.1 - 5.3e-14 52.3 0.0 1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 GAM34588.1 - 2.3e-10 40.0 4.2 4.6e-10 39.1 4.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 GAM34588.1 - 1e-06 29.0 8.8 2e-06 28.0 8.8 1.6 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 GAM34588.1 - 0.00014 22.1 0.0 0.00037 20.7 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 GAM34588.1 - 0.00099 19.0 6.5 0.002 18.1 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING-like PF08746.11 GAM34588.1 - 0.013 15.8 5.5 0.032 14.5 5.5 1.7 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 GAM34588.1 - 0.017 15.1 2.5 0.047 13.7 2.5 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 GAM34588.1 - 0.018 14.9 7.8 0.039 13.8 7.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM34588.1 - 0.026 14.3 8.9 0.053 13.4 8.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAM34588.1 - 0.094 13.0 8.4 0.31 11.4 8.4 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain PHD PF00628.29 GAM34588.1 - 0.37 10.7 5.6 0.8 9.6 5.6 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 GAM34588.1 - 1.1 9.0 8.0 2.3 7.9 8.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 GAM34588.1 - 1.5 9.0 6.2 2.8 8.2 5.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Arm PF00514.23 GAM34589.1 - 1.2e-78 256.9 30.7 3.6e-13 49.1 0.1 11.3 11 1 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAM34589.1 - 2.2e-19 69.6 12.8 0.00011 22.5 0.0 7.5 4 2 4 8 8 8 5 HEAT repeats HEAT_EZ PF13513.6 GAM34589.1 - 2.2e-19 69.5 14.2 0.019 15.4 0.1 8.5 7 2 2 9 9 9 5 HEAT-like repeat HEAT PF02985.22 GAM34589.1 - 2.4e-17 61.6 15.2 0.016 15.4 0.0 9.7 10 0 0 10 10 10 4 HEAT repeat Arm_2 PF04826.13 GAM34589.1 - 6.9e-14 51.9 3.8 3.8e-09 36.4 1.7 2.4 1 1 1 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 GAM34589.1 - 2.6e-12 46.1 10.5 8.7e-09 34.5 0.8 3.0 2 1 1 3 3 3 2 Adaptin N terminal region KAP PF05804.12 GAM34589.1 - 8.2e-12 44.1 0.2 1.5e-11 43.2 0.2 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 GAM34589.1 - 2.4e-09 36.9 2.4 0.00064 19.1 1.6 3.5 2 1 1 3 3 3 2 V-ATPase subunit H DUF3361 PF11841.8 GAM34589.1 - 5.1e-06 26.5 7.0 0.042 13.8 0.0 4.5 2 1 2 5 5 5 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 GAM34589.1 - 7.7e-06 26.0 1.9 5.7 7.1 0.0 5.3 2 1 5 7 7 7 1 V-ATPase subunit H Cnd1 PF12717.7 GAM34589.1 - 1.3e-05 25.3 9.4 0.026 14.6 0.1 5.0 1 1 4 6 6 6 2 non-SMC mitotic condensation complex subunit 1 DUF5578 PF17741.1 GAM34589.1 - 5.4e-05 22.8 11.0 0.29 10.5 0.2 5.7 2 1 3 6 6 6 1 Family of unknown function (DUF5578) Atx10homo_assoc PF09759.9 GAM34589.1 - 0.00025 21.0 7.1 4.3 7.4 0.1 5.3 3 2 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain IFRD PF05004.13 GAM34589.1 - 0.00031 20.0 5.5 0.43 9.6 0.2 4.7 1 1 3 5 5 5 2 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 GAM34589.1 - 0.0012 19.3 7.3 6.6 7.7 0.4 6.9 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAM34589.1 - 0.003 18.1 0.1 0.9 10.2 0.1 3.4 1 1 2 3 3 3 1 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 GAM34589.1 - 0.029 14.3 3.8 4.2 7.3 0.1 4.1 3 1 1 4 4 4 0 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 GAM34589.1 - 0.038 14.2 5.4 38 4.5 0.0 5.2 3 1 2 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Sdh5 PF03937.16 GAM34589.1 - 0.075 13.0 0.5 9.5 6.3 0.0 3.6 3 2 0 3 3 3 0 Flavinator of succinate dehydrogenase YqfD PF06898.11 GAM34589.1 - 0.17 10.7 0.0 0.32 9.8 0.0 1.4 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD IBB PF01749.20 GAM34589.1 - 0.18 12.3 2.9 34 5.0 0.0 4.2 4 0 0 4 4 4 0 Importin beta binding domain WAPL PF07814.13 GAM34589.1 - 0.2 10.4 10.4 1.2 7.9 2.8 3.3 2 1 1 3 3 3 0 Wings apart-like protein regulation of heterochromatin Vpu PF00558.19 GAM34589.1 - 0.38 10.6 2.3 0.48 10.2 0.6 2.0 2 0 0 2 2 2 0 Vpu protein EXOSC1 PF10447.9 GAM34590.1 - 2.5e-24 86.0 4.7 1e-23 84.0 4.7 2.0 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 GAM34590.1 - 1.8e-10 40.4 0.4 4.2e-10 39.3 0.4 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region GTP_EFTU PF00009.27 GAM34591.1 - 4.8e-59 199.2 0.0 1.1e-58 197.9 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAM34591.1 - 9.7e-16 57.6 0.0 2.7e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAM34591.1 - 4e-08 33.5 0.0 1.2e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAM34591.1 - 6e-07 29.5 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 GAM34591.1 - 9.6e-06 25.4 0.0 4.2e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV D123 PF07065.14 GAM34591.1 - 0.041 13.0 0.8 0.093 11.9 0.8 1.5 1 0 0 1 1 1 0 D123 MMR_HSR1 PF01926.23 GAM34591.1 - 0.07 13.2 0.0 0.24 11.5 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase SET PF00856.28 GAM34591.1 - 0.48 10.8 1.5 5.3 7.4 0.1 2.8 3 0 0 3 3 3 0 SET domain DUF4604 PF15377.6 GAM34592.1 - 1.1e-22 81.3 19.9 1.3e-22 81.1 19.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) CDC45 PF02724.14 GAM34592.1 - 2.5 6.3 14.3 2.7 6.2 14.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Prp19 PF08606.11 GAM34593.1 - 4.4e-33 113.1 1.1 9.6e-33 112.0 1.1 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 GAM34593.1 - 2.3e-13 50.3 0.0 1e-07 32.1 0.0 4.7 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAM34593.1 - 3.4e-10 40.3 1.9 0.0062 17.4 0.0 5.9 6 0 0 6 6 6 1 WD domain, G-beta repeat eIF2A PF08662.11 GAM34593.1 - 4.1e-05 23.5 0.0 0.049 13.5 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAM34593.1 - 0.0054 15.7 1.3 0.088 11.8 0.1 2.3 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein V_ATPase_I_N PF18670.1 GAM34593.1 - 0.0067 16.8 0.1 0.018 15.4 0.1 1.7 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain HPS3_N PF14761.6 GAM34593.1 - 0.0073 15.9 0.0 0.23 11.0 0.0 2.4 1 1 2 3 3 3 1 Hermansky-Pudlak syndrome 3 WD40_like PF17005.5 GAM34593.1 - 0.016 14.6 0.0 2.1 7.6 0.0 2.2 1 1 2 3 3 3 0 WD40-like domain zf-Nse PF11789.8 GAM34593.1 - 0.018 14.9 0.0 0.061 13.2 0.0 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Cytochrom_D1 PF02239.16 GAM34593.1 - 0.03 12.8 0.1 0.74 8.3 0.0 2.3 2 1 1 3 3 3 0 Cytochrome D1 heme domain U-box PF04564.15 GAM34593.1 - 0.035 14.3 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 U-box domain Frtz PF11768.8 GAM34593.1 - 0.048 12.0 0.0 0.59 8.4 0.0 2.4 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz L51_S25_CI-B8 PF05047.16 GAM34595.1 - 1.1e-13 50.8 0.1 2.3e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.8 GAM34596.1 - 5e-27 94.4 0.2 1.1e-26 93.2 0.1 1.7 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 GAM34596.1 - 7.9e-10 38.4 0.0 3.2e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM34596.1 - 0.033 14.3 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif DUF4769 PF15992.5 GAM34596.1 - 1.2 8.8 3.8 0.52 10.1 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4769) RL10P_insert PF17777.1 GAM34597.1 - 3.4e-23 81.4 0.0 5.6e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 GAM34597.1 - 1.5e-16 60.4 0.1 5.8e-15 55.3 0.1 2.3 1 1 0 1 1 1 1 Ribosomal protein L10 MDM10 PF12519.8 GAM34598.1 - 8.5e-144 479.9 1.9 1.7e-123 412.9 0.4 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 TIM PF00121.18 GAM34599.1 - 2.6e-89 298.8 0.1 3e-89 298.6 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF2951 PF11166.8 GAM34600.1 - 0.039 14.2 4.2 0.11 12.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) PHC2_SAM_assoc PF16616.5 GAM34600.1 - 2.8 8.8 10.6 0.25 12.1 3.5 2.6 1 1 1 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 MFS_1 PF07690.16 GAM34601.1 - 4.2e-34 118.0 25.3 6.7e-34 117.3 25.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1857 PF08982.11 GAM34602.1 - 0.089 12.6 0.6 0.092 12.6 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) Pro_isomerase PF00160.21 GAM34603.1 - 2.8e-42 144.7 0.0 5.3e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 GAM34603.1 - 0.00011 22.3 0.4 0.0018 18.4 0.0 3.0 3 1 1 4 4 4 1 U-box domain Rtf2 PF04641.12 GAM34603.1 - 0.0011 18.4 1.4 0.0011 18.4 1.4 2.7 2 1 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 GAM34603.1 - 0.0015 18.6 0.0 0.0035 17.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein EloA-BP1 PF15870.5 GAM34603.1 - 0.99 9.6 4.7 2.2 8.5 3.7 2.0 2 1 0 2 2 2 0 ElonginA binding-protein 1 YjeF_N PF03853.15 GAM34604.1 - 5.8e-40 137.0 0.2 8.5e-40 136.4 0.2 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 GAM34604.1 - 4.2e-07 30.8 3.9 4.2e-07 30.8 3.9 2.3 3 0 0 3 3 3 1 FDF domain PIF1 PF05970.14 GAM34605.1 - 4.1e-66 223.6 0.3 1.8e-50 172.2 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 GAM34605.1 - 7.2e-24 84.6 0.0 1.2e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM34605.1 - 2.9e-12 47.1 0.0 6.2e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAM34605.1 - 6.1e-08 33.0 0.0 1.8e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 GAM34605.1 - 2.3e-05 24.0 0.0 5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region UvrD_C_2 PF13538.6 GAM34605.1 - 7e-05 22.6 0.2 0.00021 21.0 0.0 1.9 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 GAM34605.1 - 0.00011 22.6 0.0 0.00024 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 GAM34605.1 - 0.00038 19.6 0.0 0.00076 18.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 GAM34605.1 - 0.00064 19.5 0.5 0.32 10.7 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 GAM34605.1 - 0.00066 20.0 0.1 0.0048 17.3 0.0 2.5 3 1 0 3 3 2 1 RNA helicase Herpes_Helicase PF02689.14 GAM34605.1 - 0.0029 15.6 0.0 0.0071 14.3 0.0 1.5 2 0 0 2 2 2 1 Helicase AAA PF00004.29 GAM34605.1 - 0.004 17.6 0.3 0.012 16.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 GAM34605.1 - 0.0045 16.2 0.0 0.0077 15.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ResIII PF04851.15 GAM34605.1 - 0.0053 16.8 0.1 0.024 14.6 0.1 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 GAM34605.1 - 0.0084 15.4 0.1 0.018 14.3 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 GAM34605.1 - 0.012 15.5 0.3 0.043 13.7 0.3 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea SH3_13 PF18335.1 GAM34605.1 - 0.013 15.4 0.1 0.055 13.3 0.1 2.1 2 0 0 2 2 1 0 ATP-dependent RecD-like DNA helicase SH3 domain PhoH PF02562.16 GAM34605.1 - 0.016 14.7 0.0 0.066 12.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein TrwB_AAD_bind PF10412.9 GAM34605.1 - 0.017 14.0 0.0 0.041 12.8 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 GAM34605.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 GAM34605.1 - 0.037 14.1 0.1 0.22 11.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 GAM34605.1 - 0.042 13.4 0.1 0.091 12.3 0.1 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain RsgA_GTPase PF03193.16 GAM34605.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 GAM34605.1 - 0.066 13.2 0.3 0.66 10.0 0.3 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 GAM34605.1 - 0.096 12.8 0.6 0.19 11.8 0.0 1.8 2 0 0 2 2 1 0 50S ribosome-binding GTPase DUF5605 PF18310.1 GAM34605.1 - 0.12 12.2 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) AAA_11 PF13086.6 GAM34605.1 - 0.16 11.8 2.2 0.4 10.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 GAM34605.1 - 0.16 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PTCB-BRCT PF12738.7 GAM34606.1 - 2.4e-49 165.1 3.6 1.1e-22 79.7 0.1 4.9 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.26 GAM34606.1 - 8.2e-29 99.8 0.1 1e-11 45.0 0.0 4.5 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAM34606.1 - 1.8e-11 44.3 0.0 0.00039 20.8 0.0 5.2 5 0 0 5 5 5 2 BRCT domain, a BRCA1 C-terminus domain Fungal_trans PF04082.18 GAM34606.1 - 2.4e-07 30.1 0.6 5.4e-07 28.9 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain LIG3_BRCT PF16759.5 GAM34606.1 - 5.7e-06 26.5 1.3 0.028 14.7 0.0 3.9 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 GAM34606.1 - 0.00032 20.7 0.0 1.9 8.6 0.1 3.7 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain CN_hydrolase PF00795.22 GAM34607.1 - 1.4e-41 142.6 0.0 3.2e-41 141.4 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Nmad3 PF18754.1 GAM34607.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 MFS_1 PF07690.16 GAM34608.1 - 4.6e-34 117.9 35.2 4.6e-34 117.9 35.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Dynamin_N PF00350.23 GAM34609.1 - 1.9e-17 63.8 0.2 8.1e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAM34609.1 - 6e-11 42.4 0.0 4.2e-09 36.5 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM34609.1 - 3.5e-05 23.4 3.7 0.00017 21.2 1.2 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain EcoR124_C PF12008.8 GAM34609.1 - 0.053 13.2 0.6 0.62 9.7 0.1 2.3 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal TsaE PF02367.17 GAM34609.1 - 0.078 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 GAM34609.1 - 0.11 13.0 0.0 0.46 11.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAM34609.1 - 0.15 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Snf7 PF03357.21 GAM34610.1 - 9.7e-36 123.0 19.8 1.3e-35 122.5 17.9 1.8 2 0 0 2 2 2 1 Snf7 YlqD PF11068.8 GAM34610.1 - 1.9 8.9 17.9 20 5.5 5.9 2.1 1 1 1 2 2 2 0 YlqD protein PP2C PF00481.21 GAM34611.1 - 5.3e-61 206.5 0.1 1.1e-49 169.4 0.1 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C Mhr1 PF12829.7 GAM34612.1 - 1e-29 102.4 0.2 2.4e-29 101.2 0.2 1.6 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF5597 PF18120.1 GAM34613.1 - 2.3e-25 89.3 0.0 4.4e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_35 PF01301.19 GAM34613.1 - 6.5e-10 39.1 0.0 3.6e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 GAM34613.1 - 2.1e-09 37.2 0.0 3.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase Sugar_tr PF00083.24 GAM34614.1 - 7e-77 259.2 18.6 7e-77 259.2 18.6 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM34614.1 - 6.4e-19 68.1 35.0 1.8e-18 66.6 35.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Atg14 PF10186.9 GAM34614.1 - 5.5e-13 48.7 20.4 9.4e-12 44.6 0.1 2.2 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 GAM34614.1 - 1.1e-05 24.6 11.2 0.021 13.7 3.8 3.1 3 0 0 3 3 3 3 Vacuolar protein sorting 38 Zn_clus PF00172.18 GAM34615.1 - 0.00036 20.6 4.0 0.00059 19.9 4.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 GAM34616.1 - 1.2e-06 28.3 2.9 6.4e-06 26.0 0.6 2.4 2 0 0 2 2 2 1 F-box-like p450 PF00067.22 GAM34617.1 - 9.1e-47 159.8 0.0 1.1e-46 159.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PalH PF08733.10 GAM34619.1 - 1.6e-99 333.0 0.0 1.2e-69 234.9 0.0 2.1 1 1 1 2 2 2 2 PalH/RIM21 TIP120 PF08623.10 GAM34620.1 - 6.2e-64 214.8 0.0 6.9e-63 211.4 0.0 2.6 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 GAM34620.1 - 1.9e-12 46.3 13.0 0.23 11.8 0.1 11.3 11 0 0 11 11 11 3 HEAT repeat HEAT_2 PF13646.6 GAM34620.1 - 1e-05 25.8 19.3 0.37 11.2 0.1 9.3 8 3 3 11 11 11 1 HEAT repeats DRIM PF07539.12 GAM34620.1 - 0.0013 17.1 4.2 0.48 8.7 0.4 4.7 3 2 0 3 3 3 1 Down-regulated in metastasis RTP1_C1 PF10363.9 GAM34620.1 - 0.0042 17.3 3.4 0.36 11.0 0.0 4.9 6 0 0 6 6 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 GAM34620.1 - 0.0089 16.1 0.0 0.75 9.8 0.0 3.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAM34620.1 - 0.067 13.7 21.7 16 6.1 0.1 10.0 11 1 1 12 12 10 0 HEAT-like repeat TAF6_C PF07571.13 GAM34620.1 - 0.12 12.8 0.0 2 8.8 0.0 3.3 1 1 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain UNC45-central PF11701.8 GAM34620.1 - 0.16 11.9 5.0 29 4.6 0.0 4.7 5 0 0 5 5 5 0 Myosin-binding striated muscle assembly central DUF3295 PF11702.8 GAM34620.1 - 0.22 10.9 0.7 0.41 9.9 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Arm PF00514.23 GAM34620.1 - 5.8 7.1 9.3 65 3.8 0.0 5.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat TRAM_LAG1_CLN8 PF03798.16 GAM34622.1 - 2.8e-39 134.9 21.8 5.4e-39 134.0 21.8 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 GAM34622.1 - 1.8e-22 78.7 0.0 1.8e-22 78.7 0.0 2.6 3 0 0 3 3 3 1 TRAM1-like protein Glyco_hydro_127 PF07944.12 GAM34623.1 - 5e-19 68.2 0.0 3.3e-16 58.9 0.0 2.2 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 DUF5011 PF16403.5 GAM34623.1 - 0.042 14.0 0.3 0.11 12.6 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5011) FAD_binding_3 PF01494.19 GAM34624.1 - 9e-93 311.3 0.0 1.1e-92 311.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM34624.1 - 5.3e-10 39.4 1.0 3.8e-07 30.0 1.1 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM34624.1 - 2.1e-06 27.2 0.1 5.2e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM34624.1 - 9.5e-05 21.6 0.1 0.15 11.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAM34624.1 - 0.00028 21.1 0.1 0.00065 19.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAM34624.1 - 0.027 13.8 0.1 0.84 8.8 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 GAM34624.1 - 0.12 12.9 0.1 0.56 10.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Transport_MerF PF11431.8 GAM34624.1 - 0.39 10.6 1.9 1.1 9.2 1.9 1.8 1 0 0 1 1 1 0 Membrane transport protein MerF Transglut_core PF01841.19 GAM34625.1 - 2.5e-12 47.2 0.1 7.6e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF553 PF04473.12 GAM34625.1 - 0.051 13.1 0.0 0.16 11.5 0.0 1.8 1 1 0 1 1 1 0 Transglutaminase-like domain Gln_amidase PF15644.6 GAM34625.1 - 0.051 14.6 0.1 0.3 12.1 0.0 2.3 2 0 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase Ras PF00071.22 GAM34626.1 - 1.3e-30 106.2 0.1 2.1e-30 105.5 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM34626.1 - 2.5e-23 82.6 0.1 4.8e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM34626.1 - 1.1e-06 28.2 0.1 2.5e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM34626.1 - 0.00014 21.3 0.1 0.00018 20.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 GAM34626.1 - 0.0058 15.5 0.1 0.92 8.3 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) CAF1C_H4-bd PF12265.8 GAM34627.1 - 6.1e-16 58.4 0.0 3.3e-15 56.1 0.0 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 GAM34627.1 - 3.3e-12 46.7 6.6 5.3e-06 27.1 0.1 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM34627.1 - 6e-08 32.9 0.4 0.00049 20.3 0.1 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM34627.1 - 0.029 13.0 1.7 0.59 8.7 0.2 2.1 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Fungal_trans PF04082.18 GAM34628.1 - 1.1e-23 83.7 0.8 1.9e-23 82.8 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAM34628.1 - 2.5e-07 30.8 15.8 0.0012 19.2 3.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM34628.1 - 6.2e-07 29.6 6.3 6.2e-07 29.6 6.3 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAM34628.1 - 0.0054 17.5 17.6 0.1 13.5 1.6 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger GEN1_C PF18380.1 GAM34628.1 - 0.3 12.0 1.2 2.6 9.0 0.4 2.6 1 1 1 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain zf-C2H2_jaz PF12171.8 GAM34628.1 - 0.47 10.8 3.5 3.1 8.2 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 GAM34628.1 - 0.5 10.2 7.3 6.3 6.7 1.0 3.0 2 0 0 2 2 2 0 zinc-finger C2H2-type Utp8 PF10395.9 GAM34629.1 - 3.8e-11 42.3 0.0 3e-07 29.3 0.0 3.1 3 0 0 3 3 3 3 Utp8 family AAA PF00004.29 GAM34630.1 - 5.7e-07 30.0 2.9 1.4e-06 28.8 0.2 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAM34630.1 - 9.9e-07 28.9 0.2 0.0008 19.4 0.0 3.4 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 GAM34630.1 - 3.1e-05 24.4 0.0 0.0001 22.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM34630.1 - 0.00037 20.8 0.2 0.016 15.5 0.1 2.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 GAM34630.1 - 0.0069 16.9 0.3 0.099 13.2 0.0 2.7 2 0 0 2 2 2 1 ABC transporter DUF815 PF05673.13 GAM34630.1 - 0.017 14.3 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DNA_pol3_delta2 PF13177.6 GAM34630.1 - 0.054 13.3 1.1 0.18 11.6 0.1 2.4 2 1 0 2 2 2 0 DNA polymerase III, delta subunit AAA_14 PF13173.6 GAM34630.1 - 0.14 12.2 0.2 1.4 9.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 GAM34630.1 - 0.46 11.0 9.6 0.39 11.2 1.3 3.0 2 1 0 2 2 2 0 AAA domain SAM_2 PF07647.17 GAM34631.1 - 3.3e-14 52.8 0.0 4.9e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 GAM34631.1 - 4.5e-13 49.6 0.0 9.1e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.30 GAM34631.1 - 7.9e-12 45.4 0.0 1.2e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 GAM34631.1 - 0.056 13.4 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Nha1_C PF08619.10 GAM34632.1 - 1.7e-118 396.8 42.3 2.2e-118 396.4 42.3 1.2 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 GAM34632.1 - 3e-77 260.0 18.2 3.7e-77 259.7 18.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CstA PF02554.14 GAM34632.1 - 0.0035 16.3 1.5 0.0089 15.0 1.5 1.6 1 0 0 1 1 1 1 Carbon starvation protein CstA YrhC PF14143.6 GAM34632.1 - 0.3 11.2 4.0 0.2 11.8 1.2 2.2 2 0 0 2 2 2 0 YrhC-like protein DUF21 PF01595.20 GAM34632.1 - 2.5 7.8 9.6 0.053 13.2 1.6 2.3 2 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain ABC2_membrane PF01061.24 GAM34633.1 - 2.5e-82 275.4 47.6 3.3e-43 147.5 12.6 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 GAM34633.1 - 9.8e-36 123.3 0.0 2.1e-17 63.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAM34633.1 - 4.5e-25 87.4 0.0 4.5e-25 87.4 0.0 3.7 4 0 0 4 4 4 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 GAM34633.1 - 1.7e-12 47.1 36.3 2.7e-06 26.7 12.0 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 GAM34633.1 - 0.00015 22.3 0.0 0.00046 20.8 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 GAM34633.1 - 0.00083 19.8 0.1 0.22 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 GAM34633.1 - 0.0015 18.3 0.5 1.1 9.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM34633.1 - 0.0015 18.4 0.3 0.18 11.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 GAM34633.1 - 0.0018 17.9 0.9 0.019 14.5 0.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAM34633.1 - 0.0054 16.6 0.0 0.36 10.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 GAM34633.1 - 0.023 15.2 0.1 2.4 8.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.6 GAM34633.1 - 0.025 14.9 0.0 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 GAM34633.1 - 0.069 12.6 0.0 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GAM34633.1 - 0.18 11.9 0.2 12 6.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 GAM34633.1 - 0.35 11.1 1.7 1.6 8.9 0.6 2.2 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 GAM34633.1 - 0.63 9.3 16.8 0.59 9.4 4.4 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein PX PF00787.24 GAM34634.1 - 1.7e-17 63.4 0.4 3.8e-17 62.3 0.4 1.6 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.6 GAM34634.1 - 0.039 14.0 1.4 0.079 13.0 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit EnY2 PF10163.9 GAM34635.1 - 0.0019 18.5 0.0 0.0082 16.5 0.0 2.0 1 1 1 2 2 2 1 Transcription factor e(y)2 AAA PF00004.29 GAM34636.1 - 2.4e-97 322.5 0.0 2e-47 160.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM34636.1 - 2.6e-23 81.5 4.4 4e-13 48.9 0.5 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 GAM34636.1 - 3.1e-19 68.9 1.1 8.5e-19 67.5 0.4 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 GAM34636.1 - 2e-14 54.1 0.0 1.1e-07 32.2 0.0 3.1 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GAM34636.1 - 3.1e-14 53.0 0.0 6.7e-06 25.9 0.0 3.2 4 1 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAM34636.1 - 2.4e-12 47.6 0.0 0.00013 22.4 0.0 4.6 3 2 1 4 4 3 2 AAA ATPase domain AAA_33 PF13671.6 GAM34636.1 - 4.1e-12 46.5 0.0 2.7e-05 24.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 GAM34636.1 - 3.3e-11 43.3 0.3 3e-05 24.0 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 GAM34636.1 - 1.8e-09 37.3 0.1 0.0013 18.0 0.0 2.8 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 GAM34636.1 - 3.5e-09 37.1 0.4 0.029 14.7 0.0 4.2 2 2 2 4 4 4 2 AAA domain CDC48_2 PF02933.17 GAM34636.1 - 1.9e-08 34.0 0.0 4.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 GAM34636.1 - 6.8e-08 32.1 0.2 0.0062 16.0 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAM34636.1 - 5.5e-07 30.2 0.0 0.021 15.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 GAM34636.1 - 7.3e-07 29.3 0.0 0.018 15.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain ATPase PF06745.13 GAM34636.1 - 8.1e-07 28.6 0.1 0.52 9.6 0.0 3.4 3 0 0 3 3 3 2 KaiC RNA_helicase PF00910.22 GAM34636.1 - 9.2e-07 29.2 0.0 0.041 14.3 0.0 2.8 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 GAM34636.1 - 9.8e-07 28.7 0.0 0.035 13.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 GAM34636.1 - 1.1e-06 28.4 3.9 0.34 10.5 0.1 4.8 3 2 2 5 5 5 2 AAA domain Vps4_C PF09336.10 GAM34636.1 - 1.9e-06 27.8 0.1 2.1e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 GAM34636.1 - 2e-06 27.5 0.0 0.02 14.4 0.0 3.3 3 1 0 3 3 3 2 P-loop containing dynein motor region AAA_24 PF13479.6 GAM34636.1 - 7.1e-06 25.9 0.0 0.13 11.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 GAM34636.1 - 1.1e-05 24.7 0.0 0.006 15.8 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 GAM34636.1 - 1.2e-05 25.6 0.1 0.19 12.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain Parvo_NS1 PF01057.17 GAM34636.1 - 1.3e-05 24.5 0.1 0.043 12.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 GAM34636.1 - 2.5e-05 24.2 0.0 0.11 12.3 0.0 3.0 3 0 0 3 3 3 2 Bacterial dnaA protein Sigma54_activat PF00158.26 GAM34636.1 - 4.2e-05 23.3 0.0 0.51 10.0 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 GAM34636.1 - 5.6e-05 23.7 0.0 0.22 12.0 0.0 3.4 2 1 0 2 2 2 1 ABC transporter AAA_17 PF13207.6 GAM34636.1 - 0.00013 22.4 0.1 0.6 10.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain TsaE PF02367.17 GAM34636.1 - 0.00017 21.6 0.0 0.36 10.9 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 GAM34636.1 - 0.00024 21.1 0.0 0.086 12.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 GAM34636.1 - 0.00028 20.4 0.3 0.78 9.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 GAM34636.1 - 0.00031 20.6 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 GAM34636.1 - 0.00032 20.6 0.0 1.1 9.0 0.0 2.6 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 GAM34636.1 - 0.00052 20.0 0.0 2.3 8.0 0.0 3.6 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 GAM34636.1 - 0.00075 19.4 0.1 0.41 10.6 0.0 2.9 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.9 GAM34636.1 - 0.0014 18.0 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 GAM34636.1 - 0.0015 18.3 0.4 1.4 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 GAM34636.1 - 0.0035 17.1 0.0 0.34 10.6 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 GAM34636.1 - 0.0059 15.8 0.0 1.2 8.3 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.6 GAM34636.1 - 0.0067 16.8 1.2 6.1 7.2 0.0 3.5 3 1 0 4 4 2 0 AAA domain IPT PF01745.16 GAM34636.1 - 0.0089 15.4 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase NTPase_1 PF03266.15 GAM34636.1 - 0.0091 15.9 0.8 2.2 8.2 0.0 3.9 4 0 0 4 4 3 1 NTPase Zeta_toxin PF06414.12 GAM34636.1 - 0.015 14.6 0.0 6.1 6.1 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin KAP_NTPase PF07693.14 GAM34636.1 - 0.017 14.4 0.3 0.94 8.6 0.0 3.0 2 2 1 4 4 4 0 KAP family P-loop domain Sigma54_activ_2 PF14532.6 GAM34636.1 - 0.023 14.8 0.0 3.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Cytidylate_kin PF02224.18 GAM34636.1 - 0.031 14.0 0.0 5.7 6.6 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase UFD1 PF03152.14 GAM34636.1 - 0.031 13.8 0.0 0.26 10.8 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Zot PF05707.12 GAM34636.1 - 0.043 13.4 0.0 2 8.0 0.0 3.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AFG1_ATPase PF03969.16 GAM34636.1 - 0.076 11.9 0.0 11 4.8 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_6 PF12774.7 GAM34636.1 - 0.15 11.0 0.1 9 5.1 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region eIF-1a PF01176.19 GAM34636.1 - 0.27 11.1 1.1 1.7 8.5 0.2 2.5 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 E1-E2_ATPase PF00122.20 GAM34637.1 - 1.1e-48 165.2 0.4 1.3e-47 161.6 0.2 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAM34637.1 - 6.1e-35 121.4 0.0 1.4e-34 120.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAM34637.1 - 4.6e-25 87.8 0.1 3.3e-12 46.6 0.0 3.0 3 0 0 3 3 3 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 GAM34637.1 - 2.9e-08 33.8 0.3 9.8e-05 22.2 0.2 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAM34637.1 - 1.6e-06 28.7 0.0 3.7e-05 24.2 0.0 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase CmcI PF04989.12 GAM34637.1 - 0.0059 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Cephalosporin hydroxylase DAHP_snth_FXD PF18152.1 GAM34637.1 - 0.085 12.7 0.2 18 5.2 0.0 3.6 3 0 0 3 3 3 0 DAHP synthase ferredoxin-like domain DIT1_PvcA PF05141.12 GAM34638.1 - 6.3e-80 268.6 0.0 9.6e-80 268.0 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DJ-1_PfpI PF01965.24 GAM34638.1 - 5.6e-06 26.3 0.0 2.5e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family POTRA PF07244.15 GAM34638.1 - 0.012 16.1 0.0 0.028 15.0 0.0 1.6 1 0 0 1 1 1 0 Surface antigen variable number repeat ThiJ_like PF17124.5 GAM34638.1 - 0.033 13.9 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like DIT1_PvcA PF05141.12 GAM34639.1 - 2.9e-88 295.9 0.0 4.8e-88 295.2 0.0 1.4 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Amidase PF01425.21 GAM34639.1 - 1.7e-33 116.3 0.3 3.8e-33 115.1 0.3 1.5 1 0 0 1 1 1 1 Amidase PEX11 PF05648.14 GAM34640.1 - 7.6e-14 51.7 0.4 1.4e-12 47.6 0.1 2.0 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) GST_N_4 PF17172.4 GAM34640.1 - 0.036 14.8 0.2 0.14 12.9 0.1 2.0 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Mpv17_PMP22 PF04117.12 GAM34641.1 - 1.6e-12 47.4 2.1 8.8e-12 45.1 1.3 2.1 1 1 1 2 2 2 1 Mpv17 / PMP22 family Cullin_binding PF03556.15 GAM34642.1 - 1.8e-30 105.9 2.0 1.8e-30 105.9 2.0 1.6 2 0 0 2 2 2 1 Cullin binding UPF0113_N PF17833.1 GAM34642.1 - 9.8e-26 90.1 0.1 1.8e-25 89.3 0.1 1.5 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 GAM34642.1 - 1.3e-21 76.7 0.0 2.5e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain UBA_4 PF14555.6 GAM34642.1 - 6.2e-13 48.3 0.7 1.6e-12 47.0 0.3 1.9 2 0 0 2 2 2 1 UBA-like domain ChW PF07538.11 GAM34642.1 - 0.0045 16.9 0.8 0.53 10.3 0.0 2.7 2 0 0 2 2 2 1 Clostridial hydrophobic W CRAL_TRIO_N PF03765.15 GAM34642.1 - 0.0052 17.0 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TAP_C PF03943.13 GAM34642.1 - 0.045 13.4 0.2 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 TAP C-terminal domain PUA PF01472.20 GAM34642.1 - 0.049 13.6 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 PUA domain PP1 PF07430.11 GAM34642.1 - 0.2 11.8 0.0 0.43 10.7 0.0 1.5 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain NOC3p PF07540.11 GAM34643.1 - 1.5e-30 105.4 0.2 6.2e-30 103.5 0.2 2.1 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 GAM34643.1 - 8.2e-24 84.5 3.4 1.7e-23 83.5 0.0 2.9 2 1 0 2 2 2 1 CBF/Mak21 family DUF4611 PF15387.6 GAM34643.1 - 0.0045 17.2 2.8 0.0045 17.2 2.8 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4611) Voldacs PF03517.13 GAM34643.1 - 1.2 9.2 5.6 11 6.1 0.1 2.8 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling DUF1349 PF07081.11 GAM34645.1 - 1.5e-21 77.0 0.0 1.8e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) MRP-L46 PF11788.8 GAM34646.1 - 7.2e-39 133.2 0.3 1.2e-38 132.5 0.3 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 GAM34646.1 - 0.00039 20.5 0.0 0.00079 19.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain CAF1 PF04857.20 GAM34647.1 - 9.8e-76 254.9 0.0 1.2e-75 254.7 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease TFIIF_alpha PF05793.12 GAM34648.1 - 0.0092 14.6 9.2 0.012 14.2 9.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pex26 PF07163.12 GAM34648.1 - 0.12 11.7 4.2 0.098 12.0 2.0 1.9 2 0 0 2 2 2 0 Pex26 protein DUF572 PF04502.13 GAM34648.1 - 0.19 11.3 9.8 0.33 10.5 9.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S64 PF08192.11 GAM34648.1 - 0.65 8.4 6.1 1.5 7.2 6.1 1.5 1 1 0 1 1 1 0 Peptidase family S64 SRP-alpha_N PF04086.13 GAM34648.1 - 0.66 9.9 11.0 1.1 9.2 11.0 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal OrfB_IS605 PF01385.19 GAM34648.1 - 0.81 9.9 6.9 22 5.3 0.1 2.6 2 0 0 2 2 2 0 Probable transposase FbpA PF05833.11 GAM34648.1 - 2.7 6.7 11.8 9.7 4.8 11.8 1.7 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) SBF_like PF13593.6 GAM34649.1 - 1.5e-95 320.1 18.0 1.7e-95 319.9 18.0 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.18 GAM34649.1 - 0.002 16.6 0.5 0.002 16.6 0.5 2.9 2 2 1 3 3 3 2 Membrane transport protein Mito_carr PF00153.27 GAM34650.1 - 1e-64 214.4 0.4 3e-21 75.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sacchrp_dh_NADP PF03435.18 GAM34651.1 - 0.0019 18.5 0.0 0.021 15.1 0.0 2.3 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain EP400_N PF15790.5 GAM34651.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal Abhydrolase_1 PF00561.20 GAM34652.1 - 8e-20 71.6 0.2 3.8e-16 59.5 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM34652.1 - 6.7e-16 59.5 0.1 8.9e-16 59.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM34652.1 - 2.2e-13 50.0 0.0 3.7e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 GAM34652.1 - 0.0028 17.5 0.0 0.07 13.0 0.0 2.5 2 1 0 3 3 3 1 Lipase (class 3) DUF3530 PF12048.8 GAM34652.1 - 0.034 13.6 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Pinin_SDK_memA PF04696.13 GAM34653.1 - 4.7e-30 104.3 14.7 4.7e-30 104.3 14.7 3.1 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region Cofilin_ADF PF00241.20 GAM34654.1 - 6.7e-27 93.7 0.0 1.1e-15 57.4 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein NMT1 PF09084.11 GAM34655.1 - 4.9e-79 265.3 0.0 6.6e-79 264.8 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 GAM34655.1 - 0.00077 19.2 0.3 0.085 12.5 0.0 3.2 3 1 1 4 4 4 1 NMT1-like family Phosphonate-bd PF12974.7 GAM34655.1 - 0.049 13.2 0.0 0.12 11.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Ntox50 PF15542.6 GAM34655.1 - 0.18 12.6 0.0 0.46 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin 50 PHD PF00628.29 GAM34656.1 - 5.2e-09 35.9 5.1 5.2e-09 35.9 5.1 2.5 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 GAM34656.1 - 1.3e-08 35.0 1.3 1.3e-08 35.0 1.3 3.3 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 GAM34656.1 - 5.9e-08 32.9 0.5 5.9e-08 32.9 0.5 2.7 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAM34656.1 - 2.5e-06 27.2 2.8 2.5e-06 27.2 2.8 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 GAM34656.1 - 1e-05 24.9 2.1 1e-05 24.9 2.1 1.8 2 0 0 2 2 2 1 PHD-finger zf-C3HC4 PF00097.25 GAM34656.1 - 1.8e-05 24.5 0.3 1.8e-05 24.5 0.3 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM34656.1 - 1.9e-05 24.4 0.7 1.9e-05 24.4 0.7 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAM34656.1 - 0.00013 21.9 0.2 0.00013 21.9 0.2 2.7 4 0 0 4 4 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAM34656.1 - 0.00066 19.5 0.7 0.00066 19.5 0.7 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAM34656.1 - 0.0017 18.3 0.2 0.0017 18.3 0.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 GAM34656.1 - 0.0037 17.0 1.6 0.03 14.1 0.1 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAM34656.1 - 0.0079 16.2 1.1 0.0079 16.2 1.1 2.6 2 1 0 2 2 1 1 RING-type zinc-finger DZR PF12773.7 GAM34656.1 - 0.011 15.7 4.1 0.31 11.1 0.5 3.0 1 1 1 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.12 GAM34656.1 - 0.025 14.9 1.7 9.9 6.6 1.0 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_17 PF17120.5 GAM34656.1 - 0.035 13.7 0.9 0.035 13.7 0.9 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 GAM34656.1 - 0.066 13.4 1.9 0.22 11.7 1.9 1.9 1 0 0 1 1 1 0 RING-variant domain zf-PHD-like PF15446.6 GAM34656.1 - 0.098 12.3 1.9 0.42 10.2 0.3 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zinc_ribbon_2 PF13240.6 GAM34656.1 - 0.16 11.7 1.7 4.5 7.1 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain FYVE_2 PF02318.16 GAM34656.1 - 0.35 11.1 1.1 32 4.8 0.1 2.8 1 1 1 2 2 2 0 FYVE-type zinc finger zf-RING-like PF08746.11 GAM34656.1 - 0.94 9.8 7.6 0.86 10.0 1.6 2.5 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.6 GAM34656.1 - 4.7 7.2 9.2 2 8.4 2.4 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 GPI2 PF06432.11 GAM34657.1 - 0.013 15.0 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase Tim17 PF02466.19 GAM34657.1 - 0.12 12.7 2.6 7.3 7.0 2.6 2.2 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family RRM_1 PF00076.22 GAM34658.1 - 1.4e-12 47.2 1.3 1.6e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hamartin PF04388.12 GAM34658.1 - 2.7 6.5 15.8 3.5 6.2 15.8 1.1 1 0 0 1 1 1 0 Hamartin protein PNP_UDP_1 PF01048.20 GAM34659.1 - 2.3e-09 36.9 0.0 3.9e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily MFS_1 PF07690.16 GAM34660.1 - 2.9e-52 177.8 29.4 2e-47 161.8 17.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 GAM34660.1 - 6e-08 31.5 5.8 6e-08 31.5 5.8 2.7 2 2 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.20 GAM34660.1 - 0.00023 19.6 1.5 0.00099 17.5 1.3 3.5 3 1 1 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 GAM34660.1 - 0.025 13.5 26.8 0.017 14.0 1.6 3.9 3 1 1 4 4 4 0 Sugar (and other) transporter MFS_4 PF06779.14 GAM34660.1 - 0.081 12.2 21.2 1.3 8.3 8.1 3.1 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Sec2p PF06428.11 GAM34661.1 - 3e-10 39.9 8.7 3e-10 39.9 8.7 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF4795 PF16043.5 GAM34661.1 - 0.0096 15.5 5.9 0.37 10.4 0.1 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4795) Exonuc_VII_L PF02601.15 GAM34661.1 - 0.013 15.1 12.7 0.22 11.1 6.9 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit ERM PF00769.19 GAM34661.1 - 0.014 15.2 17.0 0.34 10.7 5.7 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.9 GAM34661.1 - 0.019 15.2 18.9 0.12 12.6 9.1 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 ATG16 PF08614.11 GAM34661.1 - 0.05 13.8 27.0 2 8.6 4.5 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) PAT1 PF09770.9 GAM34661.1 - 0.12 10.6 12.5 0.14 10.4 12.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-ribbon_3 PF13248.6 GAM34661.1 - 0.14 11.7 0.4 0.22 11.0 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DUF1978 PF09321.10 GAM34661.1 - 0.19 11.0 8.1 0.71 9.1 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) TMPIT PF07851.13 GAM34661.1 - 0.3 10.3 9.3 0.78 8.9 0.8 2.1 2 0 0 2 2 2 0 TMPIT-like protein Lar_restr_allev PF14354.6 GAM34661.1 - 0.44 10.9 1.7 1.3 9.5 1.7 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar TACC_C PF05010.14 GAM34661.1 - 0.63 9.8 16.9 0.54 10.0 0.6 2.8 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Nsp1_C PF05064.13 GAM34661.1 - 0.66 9.8 12.7 0.35 10.7 2.7 2.7 2 1 1 3 3 3 0 Nsp1-like C-terminal region FAM76 PF16046.5 GAM34661.1 - 0.66 9.3 9.7 1.2 8.4 9.2 1.6 1 1 1 2 2 2 0 FAM76 protein DUF724 PF05266.14 GAM34661.1 - 0.67 9.8 12.4 0.47 10.2 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Cluap1 PF10234.9 GAM34661.1 - 0.78 9.1 14.7 0.64 9.4 8.5 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF16 PF01519.16 GAM34661.1 - 0.88 10.1 6.9 15 6.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4407 PF14362.6 GAM34661.1 - 1 8.7 15.6 1.3 8.3 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Laminin_II PF06009.12 GAM34661.1 - 2.4 8.2 14.2 4.2 7.4 5.0 2.2 2 0 0 2 2 2 0 Laminin Domain II SlyX PF04102.12 GAM34661.1 - 4 8.1 20.1 4.6 7.9 4.5 3.8 2 2 2 4 4 4 0 SlyX HAUS6_N PF14661.6 GAM34661.1 - 4.2 6.9 15.6 2.1 7.9 5.0 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus V_ATPase_I PF01496.19 GAM34661.1 - 4.8 5.0 5.7 3.9 5.3 0.4 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Lebercilin PF15619.6 GAM34661.1 - 8.3 6.0 24.1 6.8 6.3 2.4 2.4 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease YlqD PF11068.8 GAM34661.1 - 8.9 6.7 19.4 0.56 10.6 6.0 2.4 2 0 0 2 2 2 0 YlqD protein Heme_oxygenase PF01126.20 GAM34662.1 - 1.3e-12 47.9 0.0 6.8e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 Heme oxygenase MFS_1 PF07690.16 GAM34663.1 - 8e-40 136.8 37.5 8e-40 136.8 37.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM34663.1 - 6.5e-12 45.0 0.1 6.5e-12 45.0 0.1 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter Fmp27 PF10344.9 GAM34664.1 - 3.1e-234 780.0 0.0 4.9e-233 776.0 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 GAM34664.1 - 1.6e-196 653.8 1.5 1.6e-196 653.8 1.5 3.7 4 1 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 GAM34664.1 - 5.1e-170 566.5 4.5 5.1e-170 566.5 4.5 2.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 GAM34664.1 - 8.3e-56 188.4 0.2 3.7e-55 186.3 0.0 2.2 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 GAM34664.1 - 9.9e-55 184.7 0.8 2.2e-54 183.6 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 GAM34664.1 - 3.4e-33 114.4 0.0 1.6e-31 109.1 0.0 3.4 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Glyco_tranf_2_3 PF13641.6 GAM34666.1 - 1.8e-20 73.8 0.0 2.7e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAM34666.1 - 6.9e-20 71.8 0.1 6.9e-20 71.8 0.1 3.0 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAM34666.1 - 1.7e-16 60.5 0.0 2.8e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF5336 PF17270.2 GAM34666.1 - 0.018 14.7 0.2 0.018 14.7 0.2 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5336) Cellulose_synt PF03552.14 GAM34666.1 - 0.21 10.1 0.1 2.8 6.3 0.0 2.1 1 1 1 2 2 2 0 Cellulose synthase FA_hydroxylase PF04116.13 GAM34667.1 - 1.2e-23 83.9 14.3 1.2e-23 83.9 14.3 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Acetyltransf_3 PF13302.7 GAM34668.1 - 6.6e-24 85.2 0.0 7.5e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM34668.1 - 3.2e-07 30.6 0.0 1.3e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAM34668.1 - 0.0044 16.9 0.0 0.042 13.8 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 GAM34668.1 - 0.0081 15.9 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cellulase PF00150.18 GAM34669.1 - 5.5e-19 68.7 1.0 8.3e-19 68.1 1.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) T2SSI PF02501.17 GAM34669.1 - 0.099 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I Aminotran_1_2 PF00155.21 GAM34670.1 - 9.1e-19 67.8 0.0 2e-18 66.7 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAM34670.1 - 0.0078 15.6 0.2 0.06 12.6 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GAM34670.1 - 0.0097 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 GAM34670.1 - 0.055 12.0 0.0 0.079 11.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme TPP_enzyme_N PF02776.18 GAM34671.1 - 3.8e-34 117.8 0.0 6e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAM34671.1 - 1.2e-17 64.0 0.0 2.9e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 GAM34671.1 - 2.2e-17 63.3 0.0 1.9e-15 56.9 0.0 2.7 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain FAD_binding_3 PF01494.19 GAM34672.1 - 1.1e-21 77.5 0.0 5.9e-11 42.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAM34672.1 - 5.2e-07 29.2 0.1 0.00095 18.5 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM34672.1 - 1.9e-06 28.0 0.1 1.3e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM34672.1 - 3.5e-06 26.8 0.3 2.2e-05 24.2 0.1 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM34672.1 - 1.5e-05 24.3 0.1 4.3e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAM34672.1 - 2.3e-05 23.3 0.0 0.0023 16.7 0.0 2.0 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 GAM34672.1 - 0.00019 20.6 0.5 0.02 14.0 0.1 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAM34672.1 - 0.0027 17.0 0.0 0.0077 15.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM34672.1 - 0.0031 16.8 0.6 0.087 12.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 GAM34672.1 - 0.0058 17.2 0.0 0.032 14.8 0.0 2.2 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 GAM34672.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 GAM34672.1 - 0.03 13.4 0.1 0.065 12.3 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 GAM34672.1 - 0.053 13.5 0.6 0.86 9.6 0.2 2.9 2 1 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 GAM34672.1 - 0.061 12.6 0.0 0.15 11.3 0.0 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 GAM34672.1 - 0.062 12.6 0.1 0.17 11.2 0.1 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amidoligase_2 PF12224.8 GAM34673.1 - 0.00019 21.2 0.0 0.018 14.7 0.1 2.3 2 1 0 2 2 2 2 Putative amidoligase enzyme adh_short PF00106.25 GAM34674.1 - 3.5e-21 75.5 0.0 1e-18 67.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM34674.1 - 1.8e-10 40.8 0.0 5.7e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAM34674.1 - 4.9e-05 22.9 0.0 6.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAM34674.1 - 0.00012 22.0 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAM34674.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) p450 PF00067.22 GAM34675.1 - 1.3e-63 215.4 0.0 1.5e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 GAM34676.1 - 9.9e-56 189.4 0.0 1.4e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C14 PF00656.22 GAM34679.1 - 1.8e-49 168.9 0.0 2.5e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Glyco_hydro_1 PF00232.18 GAM34681.1 - 1.3e-150 501.8 0.1 1.5e-150 501.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.8 GAM34681.1 - 0.0016 18.1 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Sugar_tr PF00083.24 GAM34682.1 - 1.7e-79 267.8 25.9 2.1e-79 267.5 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM34682.1 - 7.3e-25 87.6 44.8 2.6e-22 79.2 20.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM34682.1 - 1.5e-06 26.9 1.3 1.5e-06 26.9 1.3 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ICAM_N PF03921.14 GAM34682.1 - 0.11 12.2 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain Pam17 PF08566.10 GAM34682.1 - 0.12 12.2 1.0 0.23 11.3 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 MFS_1 PF07690.16 GAM34683.1 - 1.8e-28 99.5 38.0 2.9e-28 98.8 38.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily GpcrRhopsn4 PF10192.9 GAM34684.1 - 0.001 18.6 0.8 0.001 18.6 0.8 1.6 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain DUF1857 PF08982.11 GAM34685.1 - 1.1e-47 161.6 0.0 1.2e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) DUF4058 PF13267.6 GAM34685.1 - 0.022 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) DLH PF01738.18 GAM34686.1 - 0.0026 17.4 0.0 0.0092 15.6 0.0 1.7 1 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_A4 PF01828.17 GAM34687.1 - 8.6e-77 257.3 17.0 1e-76 257.1 17.0 1.0 1 0 0 1 1 1 1 Peptidase A4 family TYW3 PF02676.14 GAM34687.1 - 0.016 14.6 0.7 0.028 13.8 0.7 1.3 1 0 0 1 1 1 0 Methyltransferase TYW3 DUF1869 PF08956.10 GAM34687.1 - 0.089 12.7 0.1 0.29 11.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) Big_8 PF17961.1 GAM34687.1 - 1.3 9.2 6.8 12 6.1 0.5 2.8 2 2 0 2 2 2 0 Bacterial Ig domain Toxin_35 PF10530.9 GAM34688.1 - 0.0042 17.0 1.0 0.0047 16.9 1.0 1.2 1 0 0 1 1 1 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold Toxin_12 PF07740.12 GAM34688.1 - 0.02 15.6 3.6 0.03 15.0 3.6 1.3 1 0 0 1 1 1 0 Ion channel inhibitory toxin Lipase_GDSL PF00657.22 GAM34689.1 - 1.7e-05 24.9 0.0 0.00022 21.3 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase UQ_con PF00179.26 GAM34690.1 - 1.6e-24 86.2 0.1 2.1e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM34690.1 - 3.9e-07 29.8 0.0 5.6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Complex1_49kDa PF00346.19 GAM34691.1 - 7e-124 412.3 0.0 1e-123 411.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 GAM34691.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase DUF2990 PF11693.8 GAM34691.1 - 0.19 11.9 0.1 43 4.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2990) RNA_pol_A_bac PF01000.26 GAM34692.1 - 5.3e-27 94.4 0.0 1.3e-26 93.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GAM34692.1 - 3.5e-19 68.0 0.0 4.8e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.21 GAM34693.1 - 8.3e-67 225.1 0.0 1.2e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 GAM34693.1 - 1.6e-29 101.8 0.2 2.9e-29 101.0 0.2 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 GAM34693.1 - 0.00029 20.9 0.4 0.00082 19.4 0.0 1.9 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase E1_UFD PF09358.10 GAM34693.1 - 0.0082 16.8 0.0 0.02 15.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain Sacchrp_dh_NADP PF03435.18 GAM34693.1 - 0.034 14.4 0.1 0.61 10.4 0.1 2.8 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Ecm33 PF12454.8 GAM34693.1 - 0.062 13.5 0.6 0.13 12.4 0.6 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein UDPG_MGDP_dh_N PF03721.14 GAM34693.1 - 0.072 12.6 1.4 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 GAM34693.1 - 0.083 13.5 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PglD_N PF17836.1 GAM34693.1 - 0.17 12.5 1.6 0.33 11.6 0.5 2.0 1 1 0 2 2 2 0 PglD N-terminal domain UBA_e1_thiolCys PF10585.9 GAM34693.1 - 0.23 11.4 2.9 5.3 6.9 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site TPP_enzyme_N PF02776.18 GAM34694.1 - 4.7e-38 130.5 0.0 2.6e-37 128.1 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Telomere_reg-2 PF10193.9 GAM34694.1 - 2.1e-30 105.3 0.0 5.9e-30 103.9 0.0 1.8 1 0 0 1 1 1 1 Telomere length regulation protein TPP_enzyme_C PF02775.21 GAM34694.1 - 2.8e-20 72.6 0.0 7e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAM34694.1 - 5.3e-10 39.2 0.1 2.3e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Aminotran_1_2 PF00155.21 GAM34695.1 - 1.4e-15 57.4 0.0 1.7e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Pro-kuma_activ PF09286.11 GAM34696.1 - 1.5e-47 161.5 0.5 5.6e-47 159.6 0.1 2.1 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAM34696.1 - 2.1e-05 24.0 1.1 3.4e-05 23.3 1.1 1.2 1 0 0 1 1 1 1 Subtilase family ACC_epsilon PF13822.6 GAM34696.1 - 0.0071 17.0 0.7 0.014 16.0 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA carboxylase epsilon subunit Pkinase PF00069.25 GAM34697.1 - 4.1e-55 187.0 0.0 5.6e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM34697.1 - 2.4e-41 141.8 0.0 3.4e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM34697.1 - 4.8e-06 26.1 0.0 8.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAM34697.1 - 0.00015 20.7 0.0 0.00037 19.4 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAM34697.1 - 0.0046 16.9 0.0 0.0096 15.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAM34697.1 - 0.041 13.2 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GAM34697.1 - 0.091 12.4 0.0 0.2 11.2 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 GAM34697.1 - 0.14 11.7 0.1 0.52 9.9 0.1 1.8 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 GAM34697.1 - 0.18 10.7 1.3 0.53 9.2 0.0 2.2 3 0 0 3 3 3 0 Haspin like kinase domain F-box-like PF12937.7 GAM34698.1 - 1.2 9.1 3.8 0.68 9.9 0.8 2.3 2 0 0 2 2 2 0 F-box-like BCDHK_Adom3 PF10436.9 GAM34699.1 - 8.6e-44 149.2 0.0 1.3e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAM34699.1 - 1.1e-11 45.3 0.1 9.2e-11 42.2 0.1 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 GAM34699.1 - 0.17 11.9 0.2 0.99 9.4 0.2 2.2 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain DUF1989 PF09347.10 GAM34700.1 - 1.5e-26 93.1 0.1 6.5e-15 55.2 0.0 3.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1989) RNA_pol_Rpb2_3 PF04565.16 GAM34700.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 RIBIOP_C PF04950.12 GAM34701.1 - 6.5e-96 321.2 0.0 6.5e-96 321.2 0.0 1.7 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 GAM34701.1 - 1.5e-28 98.7 0.0 5.5e-28 96.9 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 GAM34701.1 - 2.4e-05 24.6 0.2 8.4e-05 22.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain GTP_EFTU PF00009.27 GAM34701.1 - 9.1e-05 22.1 0.0 0.014 15.0 0.0 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 GAM34701.1 - 0.0002 21.8 0.0 0.00062 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 GAM34701.1 - 0.00061 20.0 1.5 0.001 19.2 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 GAM34701.1 - 0.00067 20.1 0.0 0.0017 18.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 GAM34701.1 - 0.0026 17.8 0.1 0.0097 16.0 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase TsaE PF02367.17 GAM34701.1 - 0.0031 17.5 0.0 0.021 14.8 0.0 2.1 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 GAM34701.1 - 0.0047 17.5 0.9 0.02 15.4 0.0 2.5 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 GAM34701.1 - 0.005 16.1 0.0 0.0092 15.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 GAM34701.1 - 0.0069 16.9 3.2 0.051 14.1 0.1 3.4 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.6 GAM34701.1 - 0.0092 16.3 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 GAM34701.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 GAM34701.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 GAM34701.1 - 0.017 14.8 0.0 0.2 11.4 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 GAM34701.1 - 0.02 15.3 0.0 0.051 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 GAM34701.1 - 0.028 14.3 0.0 0.085 12.8 0.0 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 GAM34701.1 - 0.03 13.9 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 GAM34701.1 - 0.04 13.8 0.2 0.078 12.9 0.2 1.4 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 GAM34701.1 - 0.042 13.7 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 GAM34701.1 - 0.057 13.4 0.1 0.23 11.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 GAM34701.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAM34701.1 - 0.063 13.3 0.1 0.22 11.6 0.1 1.9 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 GAM34701.1 - 0.079 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Roc PF08477.13 GAM34701.1 - 0.099 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 GAM34701.1 - 0.099 12.5 0.1 0.44 10.5 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 GAM34701.1 - 0.17 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Rad17 PF03215.15 GAM34701.1 - 0.17 11.8 0.1 0.63 9.9 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_11 PF13086.6 GAM34701.1 - 0.19 11.5 0.0 0.19 11.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain Wzy_C_2 PF11846.8 GAM34701.1 - 0.4 10.6 0.8 0.73 9.7 0.8 1.3 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Whi5 PF08528.11 GAM34702.1 - 0.08 12.6 0.3 0.15 11.7 0.3 1.5 1 0 0 1 1 1 0 Whi5 like Glyoxalase PF00903.25 GAM34704.1 - 9.9e-12 45.2 0.0 3.2e-11 43.5 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAM34704.1 - 0.00046 20.4 0.0 0.00074 19.8 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TxDE PF18711.1 GAM34704.1 - 0.16 12.1 0.0 1.4 9.1 0.0 2.3 1 1 0 1 1 1 0 Toxoflavin-degrading enzyme PWI PF01480.17 GAM34705.1 - 9e-10 38.7 0.2 1.7e-09 37.8 0.2 1.4 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 GAM34705.1 - 1.8e-07 30.9 0.6 1.5e-06 27.9 0.1 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM34705.1 - 9.7e-06 25.5 0.0 0.00067 19.6 0.1 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 GAM34705.1 - 0.00092 19.1 1.6 0.0019 18.0 1.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4523 PF15023.6 GAM34705.1 - 0.033 14.0 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) RRM_5 PF13893.6 GAM34705.1 - 0.049 13.2 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 GAM34705.1 - 0.05 13.4 1.7 0.087 12.7 1.7 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger Limkain-b1 PF11608.8 GAM34705.1 - 0.095 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Limkain b1 PHM7_cyt PF14703.6 GAM34705.1 - 0.14 12.4 3.6 0.97 9.6 0.0 2.5 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF4283 PF14111.6 GAM34705.1 - 0.16 11.5 0.1 0.34 10.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) Torus PF16131.5 GAM34705.1 - 0.4 11.4 2.2 0.49 11.1 0.1 2.1 2 0 0 2 2 2 0 Torus domain MAT1 PF06391.13 GAM34705.1 - 0.54 10.1 15.3 0.47 10.3 13.7 1.6 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Ribosomal_L37 PF08561.10 GAM34705.1 - 1.6 9.2 8.0 3.5 8.2 8.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 Borrelia_P83 PF05262.11 GAM34705.1 - 6.3 5.2 10.6 9.2 4.6 10.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein GTP_EFTU PF00009.27 GAM34706.1 - 1.5e-66 223.7 0.2 2e-66 223.2 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GAM34706.1 - 3.5e-32 110.7 0.0 7e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 GAM34706.1 - 1.2e-21 76.6 0.0 2.9e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 GAM34706.1 - 1.6e-13 50.5 0.0 4.4e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 GAM34706.1 - 2.7e-13 50.1 0.1 1.2e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAM34706.1 - 0.00015 21.8 0.1 0.00031 20.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Solute_trans_a PF03619.16 GAM34708.1 - 1.1e-43 149.6 1.3 1.4e-43 149.4 1.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Dynactin PF12455.8 GAM34710.1 - 1.1e-95 320.2 9.8 1.1e-95 320.2 9.8 3.8 3 1 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 GAM34710.1 - 2e-22 79.0 0.2 3.5e-22 78.2 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain Hydrolase PF00702.26 GAM34710.1 - 0.00044 20.6 0.0 0.00044 20.6 0.0 3.9 4 1 0 4 4 4 1 haloacid dehalogenase-like hydrolase DUF2353 PF09789.9 GAM34710.1 - 0.011 15.1 76.4 0.006 16.0 9.9 3.8 3 1 1 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) TMEM215 PF15746.5 GAM34710.1 - 0.13 11.7 1.6 0.51 9.8 1.6 2.0 1 0 0 1 1 1 0 TMEM215 family TMF_DNA_bd PF12329.8 GAM34710.1 - 0.35 10.9 80.0 0.027 14.5 12.1 9.3 6 2 5 11 11 11 0 TATA element modulatory factor 1 DNA binding HsbA PF12296.8 GAM34710.1 - 0.4 11.1 3.1 5.5 7.4 0.1 4.3 3 1 1 4 4 4 0 Hydrophobic surface binding protein A DUF3452 PF11934.8 GAM34710.1 - 1.3 8.6 3.5 1.2 8.6 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) FPP PF05911.11 GAM34710.1 - 3.3 5.8 86.1 0.95 7.6 14.1 4.2 2 1 2 4 4 4 0 Filament-like plant protein, long coiled-coil KH_1 PF00013.29 GAM34712.1 - 1.1e-31 108.4 0.6 9.4e-07 28.6 0.1 7.2 7 0 0 7 7 7 4 KH domain SUV3_C PF12513.8 GAM34712.1 - 0.19 11.7 0.0 0.54 10.2 0.0 1.9 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal Chitin_synth_2 PF03142.15 GAM34713.1 - 5.8e-246 817.2 2.4 9.2e-246 816.5 2.4 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 GAM34713.1 - 1.4e-68 231.7 0.0 1e-67 228.9 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 GAM34713.1 - 4.1e-21 74.9 0.2 1.4e-16 60.4 0.0 3.5 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 GAM34713.1 - 2.7e-15 56.0 0.0 1.1e-14 54.0 0.1 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 GAM34713.1 - 8.4e-11 42.2 0.0 5.8e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAM34713.1 - 2e-09 37.7 2.4 5.1e-09 36.3 2.4 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAM34713.1 - 0.001 18.9 0.0 0.53 10.1 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_16 PF13191.6 GAM34713.1 - 0.051 14.0 0.8 0.54 10.6 0.1 2.7 3 0 0 3 3 3 0 AAA ATPase domain Chitin_synth_2 PF03142.15 GAM34714.1 - 2.9e-226 752.2 0.0 4.1e-226 751.7 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase GCN5L1 PF06320.13 GAM34714.1 - 4e-21 75.3 5.6 4e-21 75.3 5.6 2.1 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) Cyt-b5 PF00173.28 GAM34714.1 - 1.9e-14 53.6 0.2 2.1e-07 31.0 0.0 3.4 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 GAM34714.1 - 5.9e-13 49.2 2.4 5.9e-13 49.2 2.4 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Myosin_head PF00063.21 GAM34714.1 - 3.9e-12 45.2 0.0 2.2e-11 42.7 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.6 GAM34714.1 - 2.2e-11 44.1 0.0 6.8e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DEK_C PF08766.11 GAM34714.1 - 2.2e-07 30.7 1.1 9.4e-07 28.7 0.4 2.4 3 0 0 3 3 3 1 DEK C terminal domain Glyco_transf_21 PF13506.6 GAM34714.1 - 0.0026 17.3 0.1 0.024 14.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 GAM34714.1 - 0.016 15.0 0.0 0.52 10.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 CENP-H PF05837.12 GAM34714.1 - 0.076 13.4 0.8 0.2 12.1 0.8 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Spc7 PF08317.11 GAM34714.1 - 1.1 8.1 3.2 1.8 7.4 3.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DNA_mis_repair PF01119.19 GAM34715.1 - 4.1e-19 68.4 0.0 3.4e-18 65.4 0.0 2.4 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 GAM34715.1 - 3.9e-18 65.6 0.0 1.1e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 GAM34715.1 - 3.3e-12 46.4 0.0 1.2e-11 44.6 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAM34715.1 - 1.8e-07 31.6 0.5 7.7e-07 29.6 0.0 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TMA7 PF09072.10 GAM34715.1 - 6.4 7.7 8.6 3.6 8.5 3.8 2.8 2 0 0 2 2 2 0 Translation machinery associated TMA7 Serinc PF03348.15 GAM34716.1 - 4.6e-161 536.5 13.0 5.2e-161 536.4 13.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) YtpI PF14007.6 GAM34716.1 - 1.1 9.5 15.4 0.52 10.5 3.0 3.3 3 0 0 3 3 3 0 YtpI-like protein T2SSF PF00482.23 GAM34716.1 - 1.9 8.5 0.0 1.9 8.5 0.0 4.5 5 1 0 5 5 5 0 Type II secretion system (T2SS), protein F Nodulin-like PF06813.13 GAM34717.1 - 5.4e-23 81.8 2.8 1.2e-22 80.6 2.8 1.6 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 GAM34717.1 - 2.8e-12 46.2 33.5 5.3e-12 45.3 27.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily GATA PF00320.27 GAM34718.1 - 2.5e-15 55.8 2.6 4.4e-15 55.0 2.6 1.4 1 0 0 1 1 1 1 GATA zinc finger Pox_A_type_inc PF04508.12 GAM34718.1 - 0.00078 19.2 8.0 0.016 15.1 3.1 3.1 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat TF_Zn_Ribbon PF08271.12 GAM34718.1 - 0.022 14.3 0.6 0.039 13.5 0.6 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DivIVA PF05103.13 GAM34718.1 - 0.14 12.2 2.0 5.9 7.0 2.0 2.1 1 1 0 1 1 1 0 DivIVA protein PI3_PI4_kinase PF00454.27 GAM34719.1 - 3.9e-46 157.9 0.0 5.7e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase HET PF06985.11 GAM34720.1 - 6.9e-19 68.6 0.0 1.3e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SNF2_N PF00176.23 GAM34721.1 - 3.3e-64 216.8 0.2 5e-64 216.2 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM34721.1 - 3.9e-11 43.3 0.0 2.3e-09 37.5 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM34721.1 - 2.3e-05 24.2 0.0 5.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAM34721.1 - 3.6e-05 23.8 0.0 0.0001 22.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 GAM34721.1 - 0.084 12.9 2.6 0.15 12.1 2.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain KI67R PF08065.12 GAM34721.1 - 0.65 10.6 3.4 5.4 7.6 1.7 2.7 2 0 0 2 2 2 0 KI67R (NUC007) repeat Med21 PF11221.8 GAM34722.1 - 5.8e-54 182.3 2.3 1.4e-53 181.1 2.3 1.5 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 GAM34722.1 - 0.017 15.2 0.7 0.046 13.8 0.7 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF2034 PF10356.9 GAM34723.1 - 2.7e-40 137.8 0.0 4.2e-25 88.3 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 GAM34723.1 - 7e-08 32.5 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Spc24 PF08286.11 GAM34724.1 - 4.8e-38 129.6 2.6 6e-37 126.1 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 CLZ PF16526.5 GAM34724.1 - 0.002 18.4 7.9 0.12 12.8 1.8 2.4 2 0 0 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4795 PF16043.5 GAM34724.1 - 0.027 14.1 1.8 0.056 13.0 1.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) ING PF12998.7 GAM34724.1 - 0.027 15.0 1.7 0.14 12.8 0.1 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Prefoldin_2 PF01920.20 GAM34724.1 - 0.055 13.4 2.2 4.1 7.4 0.5 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF724 PF05266.14 GAM34724.1 - 0.09 12.6 3.8 0.19 11.5 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) WXG100 PF06013.12 GAM34724.1 - 0.11 12.8 1.2 1.8 8.8 0.1 2.4 2 1 0 2 2 2 0 Proteins of 100 residues with WXG XhlA PF10779.9 GAM34724.1 - 0.13 12.5 6.2 0.81 9.9 0.9 2.3 2 0 0 2 2 2 0 Haemolysin XhlA TPR_MLP1_2 PF07926.12 GAM34724.1 - 0.16 12.1 9.4 2.1 8.4 9.5 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 GAM34724.1 - 0.24 9.3 0.5 0.25 9.2 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.6 GAM34724.1 - 0.29 10.4 7.1 0.22 10.9 1.7 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4472 PF14739.6 GAM34724.1 - 0.57 10.9 6.8 1.5 9.6 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) SlyX PF04102.12 GAM34724.1 - 0.78 10.4 7.3 1.9 9.2 0.6 2.6 1 1 0 2 2 2 0 SlyX Spc7 PF08317.11 GAM34724.1 - 0.79 8.6 7.5 1.2 7.9 7.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Wbp11 PF09429.10 GAM34724.1 - 0.81 10.1 5.1 0.88 10.0 2.4 2.3 1 1 2 3 3 3 0 WW domain binding protein 11 APG6_N PF17675.1 GAM34724.1 - 1 9.9 11.7 1.5 9.3 11.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1690 PF07956.11 GAM34724.1 - 6.8 7.1 8.0 33 4.9 8.0 1.9 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Fis1_TPR_C PF14853.6 GAM34725.1 - 6.3e-27 93.4 1.1 6.3e-27 93.4 1.1 1.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 GAM34725.1 - 7.1e-18 64.0 0.1 1.4e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 GAM34725.1 - 0.001 19.0 1.4 0.0029 17.6 1.4 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM34725.1 - 0.048 14.2 1.1 0.088 13.3 1.0 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM34725.1 - 0.063 13.9 0.1 0.24 12.1 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM34725.1 - 0.093 12.6 2.0 0.19 11.6 2.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Bacillus_PapR PF05968.11 GAM34725.1 - 3.1 7.7 4.6 23 5.0 0.0 2.4 2 0 0 2 2 2 0 Bacillus PapR protein zinc_ribbon_9 PF14369.6 GAM34726.1 - 0.0014 18.8 3.0 0.0066 16.7 2.9 2.1 1 1 1 2 2 2 2 zinc-ribbon HypA PF01155.19 GAM34726.1 - 0.013 15.5 0.2 0.021 14.9 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 GAM34726.1 - 0.087 12.8 0.1 3.6 7.6 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Tachystatin_B PF11478.8 GAM34726.1 - 3.4 7.7 6.3 2.7 8.0 0.7 2.6 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B adh_short PF00106.25 GAM34727.1 - 1.2e-46 158.6 0.1 1.6e-46 158.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM34727.1 - 1.8e-38 132.4 0.1 2.3e-38 132.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM34727.1 - 6.2e-12 45.8 0.1 8.4e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM34727.1 - 1.2e-07 31.5 0.1 2.2e-07 30.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAM34727.1 - 4.2e-06 26.5 0.2 7.6e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM34727.1 - 8.9e-06 25.7 0.4 1.2e-05 25.3 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 GAM34727.1 - 0.00017 20.8 0.1 0.00023 20.4 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.10 GAM34727.1 - 0.00064 19.2 0.0 0.0008 18.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DFP PF04127.15 GAM34727.1 - 0.0033 17.3 0.3 0.0062 16.4 0.3 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.15 GAM34727.1 - 0.0093 15.1 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF2703 PF10865.8 GAM34727.1 - 0.029 14.6 0.0 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) GDP_Man_Dehyd PF16363.5 GAM34727.1 - 0.036 13.5 0.1 0.05 13.0 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase GYF PF02213.16 GAM34729.1 - 1.6e-17 62.9 0.3 3.9e-17 61.6 0.3 1.7 1 0 0 1 1 1 1 GYF domain PI31_Prot_N PF11566.8 GAM34730.1 - 2.9e-47 160.5 0.0 3.9e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 GAM34730.1 - 4e-16 59.9 17.9 4e-16 59.9 17.9 2.9 2 1 0 2 2 2 1 PI31 proteasome regulator DUF3747 PF12565.8 GAM34730.1 - 0.0037 16.6 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3747) Metallophos PF00149.28 GAM34731.1 - 7.5e-37 127.8 0.4 7.5e-37 127.8 0.4 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Fungal_trans PF04082.18 GAM34731.1 - 1e-15 57.5 0.5 1.9e-15 56.6 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain STPPase_N PF16891.5 GAM34731.1 - 0.096 13.1 0.1 0.24 11.9 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain HgmA PF04209.13 GAM34732.1 - 1.2e-164 548.1 0.1 1.4e-164 547.9 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase COesterase PF00135.28 GAM34733.1 - 1.5e-50 172.5 0.0 2.8e-49 168.4 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM34733.1 - 0.0057 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM34733.1 - 0.087 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AbiEii PF08843.11 GAM34733.1 - 0.15 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system HAD_2 PF13419.6 GAM34734.1 - 5.5e-17 62.4 0.0 8.3e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM34734.1 - 5e-09 36.8 0.0 2.8e-07 31.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM34734.1 - 0.0027 17.7 0.0 0.017 15.2 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like NIR_SIR PF01077.22 GAM34734.1 - 0.028 13.9 0.0 0.028 13.9 0.0 1.2 1 1 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain NT5C PF06941.12 GAM34734.1 - 0.047 13.6 0.0 0.22 11.4 0.0 1.9 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) ArabFuran-catal PF09206.11 GAM34735.1 - 2.1e-150 500.4 12.8 2.4e-150 500.2 12.8 1.0 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic SGL PF08450.12 GAM34736.1 - 0.00066 19.3 0.7 0.0015 18.1 0.6 1.8 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region WD40 PF00400.32 GAM34737.1 - 0.002 18.9 1.6 23 6.0 0.9 4.3 3 1 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_FG PF13634.6 GAM34738.1 - 7e-15 55.6 55.5 2.3e-10 41.2 25.7 2.4 1 1 1 2 2 2 2 Nucleoporin FG repeat region Neur_chan_memb PF02932.16 GAM34738.1 - 0.078 13.0 0.0 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Cpn10 PF00166.21 GAM34740.1 - 4.1e-28 97.3 0.0 6.7e-28 96.6 0.0 1.4 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Fip1 PF05182.13 GAM34740.1 - 2.3e-21 75.0 1.8 4.7e-21 74.0 1.8 1.5 1 0 0 1 1 1 1 Fip1 motif DEC-1_N PF04625.13 GAM34740.1 - 1.1 8.1 9.7 2.2 7.2 9.7 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region XAP5 PF04921.14 GAM34741.1 - 8.7e-86 287.8 0.0 1.3e-85 287.2 0.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 GAM34741.1 - 0.00093 19.7 2.9 0.0021 18.5 2.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Glyco_transf_25 PF01755.17 GAM34742.1 - 0.00024 21.0 0.0 0.00053 19.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) SKG6 PF08693.10 GAM34743.1 - 1.1e-06 27.9 3.3 2.4e-06 26.8 3.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Recep_L_domain PF01030.24 GAM34743.1 - 6.1e-06 26.3 11.8 0.018 15.1 0.7 4.3 1 1 4 5 5 5 5 Receptor L domain Ecm33 PF12454.8 GAM34743.1 - 0.0043 17.2 0.9 0.02 15.0 0.3 2.5 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein Stevor PF17410.2 GAM34743.1 - 0.14 11.7 0.3 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame GRA6 PF05084.13 GAM34743.1 - 0.15 12.0 0.8 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Granule antigen protein (GRA6) Loricrin PF15847.5 GAM34744.1 - 0.0043 16.2 0.8 0.0053 15.9 0.8 1.0 1 0 0 1 1 1 1 Major keratinocyte cell envelope protein LigB PF02900.18 GAM34745.1 - 2.7e-08 33.2 0.0 3.3e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short_C2 PF13561.6 GAM34746.1 - 3.4e-27 95.5 0.2 4.4e-27 95.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM34746.1 - 1.7e-16 60.3 0.0 2.5e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM34746.1 - 0.026 14.4 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.8 GAM34746.1 - 0.12 12.2 0.6 2.6 7.9 0.3 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.6 GAM34746.1 - 0.14 12.6 0.0 0.85 10.1 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding ThiF PF00899.21 GAM34747.1 - 1.4e-11 44.2 0.0 6.8e-11 42.0 0.0 2.3 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 GAM34747.1 - 0.0063 16.7 0.0 7.2 6.9 0.0 3.4 3 0 0 3 3 3 2 Ubiquitin-activating enzyme E1 four-helix bundle AAA PF00004.29 GAM34748.1 - 1.1e-40 139.2 0.0 7.2e-16 58.8 0.0 3.9 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 GAM34748.1 - 7.1e-18 64.6 15.5 1.2e-10 41.4 0.3 5.0 6 0 0 6 6 3 2 AAA lid domain AAA_30 PF13604.6 GAM34748.1 - 8.3e-14 51.7 0.0 0.0026 17.5 0.0 3.6 3 0 0 3 3 3 3 AAA domain AAA_5 PF07728.14 GAM34748.1 - 3.6e-09 36.8 0.5 0.02 14.9 0.0 4.2 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAM34748.1 - 2.6e-08 33.5 0.0 0.021 14.2 0.0 3.5 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 GAM34748.1 - 3.3e-08 34.1 0.4 1.4 9.3 0.0 5.1 4 1 1 5 5 5 3 AAA ATPase domain AAA_22 PF13401.6 GAM34748.1 - 4.8e-08 33.4 5.9 0.31 11.3 0.1 5.8 3 3 1 5 5 5 3 AAA domain RuvB_N PF05496.12 GAM34748.1 - 1.7e-07 31.1 0.0 0.55 10.0 0.0 4.0 3 0 0 3 3 3 3 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 GAM34748.1 - 4.7e-07 30.2 0.6 1.4 9.3 0.1 4.5 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.6 GAM34748.1 - 8.3e-06 26.1 0.9 0.64 10.2 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 GAM34748.1 - 1.1e-05 25.2 2.7 1.7 8.3 0.0 4.4 4 0 0 4 4 4 2 AAA domain IstB_IS21 PF01695.17 GAM34748.1 - 1.3e-05 25.1 0.0 1.1 9.0 0.0 3.8 3 1 0 3 3 3 1 IstB-like ATP binding protein AAA_33 PF13671.6 GAM34748.1 - 3e-05 24.2 9.3 0.39 10.9 0.0 4.9 5 0 0 5 5 4 3 AAA domain AAA_7 PF12775.7 GAM34748.1 - 5.6e-05 22.7 0.1 5.1 6.6 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region RNA_helicase PF00910.22 GAM34748.1 - 8.5e-05 22.9 0.1 4.3 7.8 0.0 3.8 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.6 GAM34748.1 - 0.0011 19.5 8.3 3.4 8.2 0.1 4.9 5 0 0 5 5 4 1 AAA domain SRP54 PF00448.22 GAM34748.1 - 0.012 15.2 2.0 0.48 10.0 0.0 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 GAM34748.1 - 0.028 14.2 0.0 37 4.2 0.0 3.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_17 PF13207.6 GAM34748.1 - 0.038 14.4 10.0 3.2 8.2 0.0 4.7 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 GAM34748.1 - 0.049 13.2 0.2 11 5.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 GAM34748.1 - 0.076 12.9 1.3 62 3.5 0.0 3.8 3 0 0 3 3 3 0 NTPase ADK PF00406.22 GAM34748.1 - 0.095 12.8 1.0 15 5.6 0.1 3.7 3 0 0 3 3 3 0 Adenylate kinase Phage_GP20 PF06810.11 GAM34748.1 - 0.2 11.4 15.2 3.4 7.5 12.9 3.1 2 1 0 2 2 2 0 Phage minor structural protein GP20 ABC_tran PF00005.27 GAM34748.1 - 0.21 12.1 9.3 7.1 7.1 0.0 4.7 5 1 0 5 5 3 0 ABC transporter AAA_11 PF13086.6 GAM34748.1 - 0.31 10.8 0.0 0.31 10.8 0.0 4.9 4 1 0 4 4 3 0 AAA domain CHAT PF12770.7 GAM34749.1 - 3.3e-15 56.3 0.1 3.3e-15 56.3 0.1 1.9 2 0 0 2 2 2 1 CHAT domain AAA_22 PF13401.6 GAM34749.1 - 1.5e-05 25.2 0.6 5.9e-05 23.4 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 GAM34749.1 - 8.1e-05 23.1 2.0 0.00013 22.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 GAM34749.1 - 0.0012 18.1 0.0 0.003 16.8 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 GAM34749.1 - 0.0016 18.4 0.1 0.0054 16.7 0.1 2.0 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 GAM34749.1 - 0.011 15.5 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GAM34749.1 - 0.034 14.1 0.0 0.087 12.7 0.0 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea FliH PF02108.16 GAM34749.1 - 0.12 12.5 0.1 0.12 12.5 0.1 3.4 4 0 0 4 4 4 0 Flagellar assembly protein FliH DUF218 PF02698.17 GAM34749.1 - 0.15 12.1 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 DUF218 domain ATPase PF06745.13 GAM34749.1 - 0.2 11.0 1.4 18 4.6 0.1 3.2 3 0 0 3 3 3 0 KaiC p450 PF00067.22 GAM34751.1 - 4.7e-31 108.0 0.0 2.1e-29 102.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 ABC_tran PF00005.27 GAM34752.1 - 2.9e-09 37.6 0.2 1.7e-08 35.0 0.2 2.0 1 1 0 1 1 1 1 ABC transporter DUF1837 PF08878.11 GAM34752.1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) Rib_5-P_isom_A PF06026.14 GAM34753.1 - 2.4e-47 160.8 0.0 4.7e-47 159.8 0.0 1.4 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 GAM34753.1 - 0.032 14.2 0.0 8.4 6.3 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain WD40 PF00400.32 GAM34754.1 - 1.4e-12 47.9 4.7 0.049 14.5 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM34754.1 - 0.014 15.7 0.0 29 5.0 0.0 4.3 2 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain TMEM131_like PF12371.8 GAM34754.1 - 0.15 12.3 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 Transmembrane protein 131-like DUF4979 PF16351.5 GAM34754.1 - 0.16 12.2 0.0 0.85 9.8 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4979) ATP_bind_1 PF03029.17 GAM34755.1 - 6.6e-76 255.3 0.0 8.3e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 GAM34755.1 - 0.0018 17.3 0.0 0.0057 15.7 0.0 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 GAM34755.1 - 0.004 17.2 0.0 0.06 13.4 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_31 PF13614.6 GAM34755.1 - 0.0094 15.9 0.0 4.6 7.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain CLP1_P PF16575.5 GAM34755.1 - 0.028 14.2 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_10 PF12846.7 GAM34755.1 - 0.033 13.1 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.6 GAM34755.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 GAM34755.1 - 0.14 12.6 1.6 0.25 11.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAM34755.1 - 0.16 12.5 0.3 0.62 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 GAM34755.1 - 0.24 10.8 0.1 0.6 9.5 0.0 1.6 1 1 1 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNase_P_Rpp14 PF01900.19 GAM34756.1 - 1.1e-31 109.2 0.0 2.6e-31 107.9 0.0 1.6 1 1 0 1 1 1 1 Rpp14/Pop5 family Citrate_synt PF00285.21 GAM34757.1 - 1.2e-20 73.9 0.0 2.6e-18 66.3 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 GAM34757.1 - 1.4e-18 67.3 0.1 3.9e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 GAM34757.1 - 5e-15 55.6 0.1 8.9e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 GAM34757.1 - 8.4e-06 25.6 0.0 8.7e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Citrate_bind PF16114.5 GAM34758.1 - 5.6e-88 293.1 0.0 7.7e-88 292.6 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 GAM34758.1 - 5.2e-08 32.7 0.0 8.2e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Fringe PF02434.16 GAM34759.1 - 1.5e-07 31.1 1.9 2.6e-06 27.1 1.4 2.7 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 GAM34759.1 - 0.031 14.1 0.0 1.1 9.1 0.0 2.1 1 1 1 2 2 2 0 Galactosyltransferase DUF604 PF04646.12 GAM34759.1 - 0.067 12.6 0.0 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF604 Glyco_transf_34 PF05637.12 GAM34759.1 - 0.48 10.1 2.3 0.8 9.4 2.3 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family adh_short PF00106.25 GAM34760.1 - 2.9e-37 128.0 0.0 3.5e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM34760.1 - 3e-16 59.7 0.0 3.8e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM34760.1 - 1.6e-06 28.1 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM34760.1 - 0.00061 19.3 0.1 0.00093 18.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAM34760.1 - 0.0011 19.0 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 GAM34760.1 - 0.017 14.5 0.3 0.032 13.6 0.3 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 GAM34760.1 - 0.018 15.6 0.1 0.038 14.6 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 GAM34760.1 - 0.02 15.2 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 GAM34760.1 - 0.026 14.4 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 GAM34760.1 - 0.03 13.5 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CBM_1 PF00734.18 GAM34761.1 - 7.4e-12 45.0 11.5 1.8e-11 43.8 11.5 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_39 PF01229.17 GAM34761.1 - 0.00029 19.6 0.0 0.00041 19.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Esterase_phd PF10503.9 GAM34762.1 - 3.2e-23 82.4 0.9 4e-23 82.1 0.9 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 GAM34762.1 - 8.6e-10 38.4 1.4 1.3e-09 37.9 1.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 GAM34762.1 - 0.00014 21.6 1.7 0.0002 21.1 1.7 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 GAM34762.1 - 0.0053 16.7 0.1 0.0079 16.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 GAM34762.1 - 0.0095 15.9 0.5 0.016 15.2 0.5 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 GAM34762.1 - 0.067 12.7 1.6 0.28 10.7 1.6 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 GAM34762.1 - 0.075 12.8 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase COesterase PF00135.28 GAM34762.1 - 0.18 10.7 4.5 0.047 12.6 1.4 1.5 2 0 0 2 2 2 0 Carboxylesterase family DUF5020 PF16412.5 GAM34762.1 - 0.33 10.8 2.8 0.19 11.6 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5020) Melibiase_2 PF16499.5 GAM34763.1 - 1.5e-65 221.2 3.2 2.6e-65 220.4 3.2 1.4 1 0 0 1 1 1 1 Alpha galactosidase A CBM_1 PF00734.18 GAM34763.1 - 1.1e-10 41.3 11.5 1.1e-10 41.3 11.5 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Melibiase_C PF17801.1 GAM34763.1 - 1.2e-09 38.1 0.1 1.5e-08 34.6 0.1 2.5 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 GAM34763.1 - 4e-05 22.7 0.1 0.00024 20.2 0.0 1.9 2 0 0 2 2 2 1 Melibiase DAG1 PF05454.11 GAM34763.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Glyco_hydro_43 PF04616.14 GAM34764.1 - 4.9e-51 173.8 8.0 6.9e-51 173.3 8.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 GAM34764.1 - 2.9e-39 134.2 5.0 2.9e-39 134.2 5.0 2.2 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 GAM34764.1 - 1.6e-08 34.6 0.5 4.4e-08 33.3 0.5 1.7 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 GAM34764.1 - 0.013 15.1 4.8 0.021 14.4 4.8 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Potex_coat PF06184.11 GAM34764.1 - 0.032 13.8 0.1 0.07 12.7 0.1 1.5 1 0 0 1 1 1 0 Potexvirus coat protein OPT PF03169.15 GAM34765.1 - 3.9e-143 478.3 53.4 4.5e-143 478.1 53.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Myelin_PLP PF01275.19 GAM34765.1 - 0.17 11.7 0.0 0.17 11.7 0.0 2.9 3 0 0 3 3 3 0 Myelin proteolipid protein (PLP or lipophilin) DNA_pol_delta_4 PF04081.13 GAM34767.1 - 6e-36 123.7 0.7 9.7e-36 123.0 0.7 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF1690 PF07956.11 GAM34767.1 - 0.13 12.7 2.5 0.1 13.0 1.0 1.5 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) ORC6 PF05460.13 GAM34768.1 - 9.1e-84 281.8 3.4 1.2e-82 278.1 3.4 1.9 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Ndc1_Nup PF09531.10 GAM34768.1 - 1.1 7.8 2.8 1.6 7.3 1.2 1.8 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Q_salvage PF10343.9 GAM34769.1 - 5.5e-133 442.8 0.1 1.9e-132 441.1 0.1 1.8 1 1 0 1 1 1 1 Potential Queuosine, Q, salvage protein family GAGA_bind PF06217.12 GAM34769.1 - 0.079 13.2 1.7 0.14 12.5 1.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family GATase_7 PF13537.6 GAM34769.1 - 0.085 12.8 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain DUF1563 PF07599.11 GAM34769.1 - 0.18 11.9 0.9 0.34 11.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) Use1 PF09753.9 GAM34769.1 - 0.23 11.2 3.2 0.4 10.4 3.2 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 Presenilin PF01080.17 GAM34769.1 - 0.72 8.6 5.6 1.1 8.0 5.6 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 GAM34769.1 - 6.2 6.6 11.5 1.4 8.7 8.2 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 ThiF PF00899.21 GAM34770.1 - 1.3e-65 221.1 0.0 2e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 GAM34770.1 - 1e-20 74.1 2.3 1.5e-20 73.5 0.5 2.1 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 GAM34770.1 - 6.4e-09 36.1 1.0 6.1e-06 26.3 0.4 2.6 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 GAM34770.1 - 0.00029 21.2 0.0 0.001 19.5 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 GAM34770.1 - 0.021 14.9 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fib_alpha PF08702.10 GAM34770.1 - 0.21 11.8 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family adh_short_C2 PF13561.6 GAM34771.1 - 1.8e-39 135.7 1.0 3.1e-32 112.0 0.4 2.8 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM34771.1 - 3.2e-35 121.3 1.0 3.3e-24 85.4 0.3 2.4 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 GAM34771.1 - 1.3e-10 41.5 1.2 6e-09 36.1 1.2 2.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM34771.1 - 0.0027 17.2 0.3 0.012 15.0 0.2 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM34771.1 - 0.0069 15.5 0.3 0.086 12.0 0.3 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 GAM34771.1 - 0.01 15.8 1.1 0.35 10.7 0.1 2.3 1 1 1 2 2 2 0 NAD(P)H-binding NAD_binding_4 PF07993.12 GAM34771.1 - 0.01 15.0 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.20 GAM34771.1 - 0.015 15.3 0.3 7.8 6.6 0.0 2.5 1 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Uds1 PF15456.6 GAM34771.1 - 0.37 11.0 3.1 0.88 9.7 0.3 2.1 2 0 0 2 2 2 0 Up-regulated During Septation Skp1_POZ PF03931.15 GAM34772.1 - 2.1e-09 37.4 0.0 3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain tRNA_int_end_N2 PF12928.7 GAM34773.1 - 3.3e-27 94.5 0.0 5.8e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 GAM34773.1 - 0.19 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Arrestin_C PF02752.22 GAM34774.1 - 1.6e-12 48.0 0.0 4.7e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.21 GAM34775.1 - 8.2e-36 123.7 0.0 4.4e-35 121.3 0.0 1.8 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-CDGSH PF09360.10 GAM34775.1 - 0.075 13.3 0.2 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 Iron-binding zinc finger CDGSH type zf-ZPR1 PF03367.13 GAM34776.1 - 6.4e-107 354.4 0.1 2.1e-54 183.7 0.0 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-RRPl_C4 PF17026.5 GAM34776.1 - 0.095 12.8 1.9 6.2 7.0 0.1 2.4 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc-ribbons_6 PF07191.12 GAM34776.1 - 0.66 10.0 4.8 0.75 9.8 0.7 2.4 2 1 0 2 2 2 0 zinc-ribbons DZR PF12773.7 GAM34776.1 - 3.2 7.8 7.3 18 5.4 2.2 3.3 3 1 0 3 3 3 0 Double zinc ribbon Lar_restr_allev PF14354.6 GAM34776.1 - 6.5 7.2 6.6 8.1 6.9 1.2 3.0 3 0 0 3 3 3 0 Restriction alleviation protein Lar DBR1 PF05011.13 GAM34777.1 - 3.7e-40 137.5 0.1 3.7e-40 137.5 0.1 2.5 3 0 0 3 3 3 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 GAM34777.1 - 2e-06 28.5 2.2 3.1e-06 27.8 2.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RTP1_C1 PF10363.9 GAM34778.1 - 4e-34 117.1 0.7 5.3e-32 110.3 0.1 3.8 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 GAM34778.1 - 2.7e-10 39.7 0.2 1.4e-09 37.5 0.1 2.3 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 2 DUF3385 PF11865.8 GAM34778.1 - 0.016 15.1 0.0 31 4.4 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 GAM34778.1 - 0.27 11.8 5.5 5.5 7.6 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat Polysacc_deac_1 PF01522.21 GAM34779.1 - 7e-28 97.0 0.0 1.4e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 GAM34779.1 - 5.1e-06 26.8 15.3 9.9e-06 25.9 15.3 1.4 1 0 0 1 1 1 1 Chitin recognition protein RBR PF17208.3 GAM34780.1 - 0.0065 17.1 0.4 0.0065 17.1 0.4 4.2 3 0 0 3 3 3 2 RNA binding Region RAD51_interact PF15696.5 GAM34780.1 - 0.017 15.2 0.6 0.038 14.1 0.6 1.6 1 0 0 1 1 1 0 RAD51 interacting motif Clathrin PF00637.20 GAM34781.1 - 5e-23 81.6 2.2 9.9e-21 74.1 0.5 2.9 2 1 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 GAM34781.1 - 4.1e-19 68.5 0.5 1e-18 67.2 0.5 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3HC4_2 PF13923.6 GAM34781.1 - 3.9e-07 29.8 6.5 9.5e-07 28.6 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 GAM34781.1 - 6e-07 29.4 6.4 1.3e-06 28.3 6.4 1.6 1 0 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 GAM34781.1 - 0.00023 21.0 6.5 0.00051 20.0 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain WD40_like PF17005.5 GAM34781.1 - 0.00042 19.8 0.2 0.0034 16.8 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain TPR_11 PF13414.6 GAM34781.1 - 0.00077 19.1 0.1 0.0022 17.6 0.1 1.8 1 0 0 1 1 1 1 TPR repeat zf-RING_2 PF13639.6 GAM34781.1 - 0.0009 19.5 6.7 0.0021 18.4 6.7 1.7 1 0 0 1 1 1 1 Ring finger domain TPR_14 PF13428.6 GAM34781.1 - 0.0027 18.4 0.2 0.27 12.1 0.0 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat zf-rbx1 PF12678.7 GAM34781.1 - 0.016 15.5 4.5 0.034 14.4 4.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF4810 PF16068.5 GAM34781.1 - 0.019 15.5 0.2 4.5 7.9 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) zf-C3HC4 PF00097.25 GAM34781.1 - 0.039 13.8 6.2 0.082 12.8 6.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 GAM34781.1 - 0.065 13.4 0.7 0.69 10.2 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps39_2 PF10367.9 GAM34781.1 - 0.065 13.7 1.0 0.22 12.0 1.0 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 GAM34781.1 - 0.47 10.5 5.7 0.17 11.9 2.3 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 GAM34781.1 - 0.56 10.3 2.1 1.4 9.0 2.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_12 PF13424.6 GAM34781.1 - 1.1 9.6 3.9 1.2 9.4 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-RING_11 PF17123.5 GAM34781.1 - 4.3 7.2 6.0 1.2 8.9 1.2 2.6 2 0 0 2 2 2 0 RING-like zinc finger TIM21 PF08294.11 GAM34782.1 - 0.041 13.7 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 TIM21 LRR_4 PF12799.7 GAM34784.1 - 2.7e-32 110.2 29.4 2.7e-06 27.6 0.1 8.1 7 1 1 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM34784.1 - 1e-23 82.9 35.2 3.6e-07 29.8 0.1 8.1 4 1 6 10 10 10 8 Leucine rich repeat LRR_9 PF14580.6 GAM34784.1 - 1.4e-10 40.9 8.7 0.00047 19.7 0.3 4.5 2 1 0 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 GAM34784.1 - 1.3e-05 25.1 20.5 21 6.2 0.9 10.3 8 2 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 GAM34784.1 - 0.00079 19.3 25.3 8.7 6.7 0.1 9.7 10 0 0 10 10 10 3 Leucine Rich repeat ApbA_C PF08546.11 GAM34785.1 - 2.6e-24 85.8 0.0 8.1e-24 84.2 0.0 1.8 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 GAM34785.1 - 1e-14 54.4 0.1 7.4e-14 51.7 0.0 2.0 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 GAM34785.1 - 0.014 14.8 0.2 0.06 12.7 0.1 1.8 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.6 GAM34785.1 - 0.17 12.4 0.0 0.41 11.1 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding IPK PF03770.16 GAM34786.1 - 2.9e-59 200.2 0.0 5.4e-59 199.4 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.10 GAM34786.1 - 0.068 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 MFS_1 PF07690.16 GAM34787.1 - 7.2e-15 54.8 20.2 7.2e-15 54.8 20.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 GAM34787.1 - 9.6e-09 35.1 5.1 2.3e-08 33.9 5.1 1.6 1 0 0 1 1 1 1 Nodulin-like Vpu PF00558.19 GAM34787.1 - 0.62 9.9 3.2 3.5 7.4 3.2 2.3 1 0 0 1 1 1 0 Vpu protein ERCC4 PF02732.15 GAM34788.1 - 4.9e-33 114.6 0.1 9.2e-33 113.7 0.1 1.5 1 0 0 1 1 1 1 ERCC4 domain Use1 PF09753.9 GAM34788.1 - 0.17 11.6 16.4 0.017 14.8 9.7 2.4 3 0 0 3 3 3 0 Membrane fusion protein Use1 Trnau1ap PF17654.1 GAM34788.1 - 0.62 11.0 4.5 1.7 9.6 1.2 2.6 2 0 0 2 2 2 0 Selenocysteine tRNA 1 associated proteins RR_TM4-6 PF06459.12 GAM34788.1 - 1.7 8.4 19.8 0.13 12.1 13.4 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF3043 PF11241.8 GAM34788.1 - 2.2 8.3 13.1 0.074 13.1 6.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF1682 PF07946.14 GAM34788.1 - 3.6 6.7 15.6 7 5.7 15.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF5523 PF17661.1 GAM34788.1 - 4.2 7.0 19.6 0.95 9.1 14.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Eapp_C PF10238.9 GAM34788.1 - 6.2 6.9 8.6 2 8.5 2.2 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein CDC45 PF02724.14 GAM34788.1 - 7.8 4.7 16.7 3 6.0 13.1 1.8 2 0 0 2 2 2 0 CDC45-like protein DUF913 PF06025.12 GAM34788.1 - 10 5.0 10.2 1.9 7.4 6.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) PNP_UDP_1 PF01048.20 GAM34789.1 - 3.4e-07 29.7 0.0 1.4e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily Glycos_transf_1 PF00534.20 GAM34791.1 - 8.4e-33 113.3 0.4 1.3e-31 109.4 0.4 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAM34791.1 - 2.8e-16 60.0 0.0 6.6e-16 58.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 GAM34791.1 - 2.2e-13 50.8 0.0 6e-13 49.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAM34791.1 - 0.0001 22.8 0.1 0.00062 20.2 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAM34791.1 - 0.095 13.1 0.4 0.36 11.3 0.0 2.1 3 0 0 3 3 3 0 Glycosyl transferases group 1 Glyco_trans_4_5 PF16994.5 GAM34791.1 - 0.12 11.9 0.0 0.4 10.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyl-transferase family 4 Tropomyosin_1 PF12718.7 GAM34791.1 - 0.16 12.1 0.6 0.32 11.2 0.6 1.4 1 0 0 1 1 1 0 Tropomyosin like LPP PF04728.13 GAM34791.1 - 0.78 10.2 4.4 2.7 8.4 0.3 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper ABC_tran_CTD PF16326.5 GAM34791.1 - 3 8.1 7.3 4.1 7.7 6.0 1.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain ACT_3 PF10000.9 GAM34792.1 - 7.6e-23 80.2 0.1 1.1e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 GAM34792.1 - 1.9e-08 34.0 0.0 2.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 ACT domain Kinesin PF00225.23 GAM34794.1 - 3.8e-89 298.9 3.4 4.7e-89 298.6 0.0 2.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAM34794.1 - 2.8e-19 69.5 0.0 8.8e-16 58.2 0.0 3.6 2 1 0 3 3 3 2 Microtubule binding DUF4108 PF13390.6 GAM34794.1 - 0.1 12.5 3.3 0.48 10.3 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4108) SLATT_5 PF18160.1 GAM34794.1 - 0.21 10.9 0.0 0.21 10.9 0.0 2.9 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 Polo_box_3 PF18544.1 GAM34794.1 - 2.7 8.7 9.9 5.6 7.7 0.1 5.4 5 0 0 5 5 5 0 Polo box domain DUF2235 PF09994.9 GAM34795.1 - 4.2e-22 78.8 0.0 5.5e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.15 GAM34796.1 - 1.9e-12 46.5 2.5 3.8e-08 32.3 0.6 3.9 2 1 1 3 3 3 2 Animal haem peroxidase PknG_rubred PF16919.5 GAM34796.1 - 0.068 13.3 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain DJ-1_PfpI PF01965.24 GAM34797.1 - 1.7e-09 37.7 0.0 1.7e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family Fungal_trans_2 PF11951.8 GAM34798.1 - 1.9e-52 178.4 1.2 3.7e-52 177.4 1.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM34798.1 - 0.0015 18.6 3.7 0.0034 17.5 3.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3385 PF11865.8 GAM34798.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) Amb_V_allergen PF03913.13 GAM34798.1 - 9.2 6.3 7.0 17 5.4 7.0 1.4 1 0 0 1 1 1 0 Amb V Allergen Mannosyl_trans3 PF11051.8 GAM34799.1 - 2.4e-53 181.3 0.0 4.1e-34 118.2 0.0 2.3 1 1 1 2 2 2 2 Mannosyltransferase putative BCIP PF13862.6 GAM34802.1 - 2.1e-73 246.5 0.2 2.8e-73 246.1 0.2 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein CM_2 PF01817.21 GAM34803.1 - 0.00043 20.6 2.5 0.029 14.7 0.2 3.0 3 1 0 3 3 3 2 Chorismate mutase type II WD40 PF00400.32 GAM34804.1 - 1.6e-29 101.5 12.3 3.5e-06 27.7 0.6 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 GAM34804.1 - 5.5e-10 38.5 5.9 0.03 13.0 0.2 5.3 4 1 2 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAM34804.1 - 2.2e-07 31.1 0.0 0.1 12.9 0.0 5.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Phage_GP20 PF06810.11 GAM34804.1 - 0.025 14.4 0.9 0.048 13.5 0.9 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 ORC_WH_C PF18137.1 GAM34804.1 - 0.55 10.3 2.5 0.39 10.8 0.3 1.8 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Sad1_UNC PF07738.13 GAM34805.1 - 1.3e-14 54.3 0.0 5.8e-10 39.3 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Med8 PF10232.9 GAM34805.1 - 0.0062 16.2 1.1 0.016 14.8 1.1 1.6 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 GOLD_2 PF13897.6 GAM34805.1 - 0.28 11.7 3.2 0.55 10.7 3.2 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Sulfotransfer_4 PF17784.1 GAM34806.1 - 3.8e-62 209.9 0.0 5.7e-62 209.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain adh_short PF00106.25 GAM34807.1 - 2.4e-13 50.0 0.0 3.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM34807.1 - 5.7e-08 32.6 0.0 8.1e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM34807.1 - 0.0001 22.3 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NUMOD1 PF07453.13 GAM34807.1 - 0.087 13.1 0.2 0.16 12.3 0.2 1.4 1 0 0 1 1 1 0 NUMOD1 domain Peptidase_A4 PF01828.17 GAM34808.1 - 1.6e-63 213.9 15.7 1.9e-63 213.7 15.7 1.0 1 0 0 1 1 1 1 Peptidase A4 family Ank_2 PF12796.7 GAM34809.1 - 1.8e-177 576.4 59.5 7.4e-20 71.3 0.2 12.1 2 2 14 16 16 16 16 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM34809.1 - 2.8e-103 337.1 2.9 3.1e-09 37.2 0.0 13.7 7 3 9 16 16 16 16 Ankyrin repeats (many copies) Ank PF00023.30 GAM34809.1 - 5.5e-102 330.2 43.2 2.1e-05 24.7 0.0 22.6 22 0 0 22 22 22 20 Ankyrin repeat Ank_3 PF13606.6 GAM34809.1 - 1.4e-101 320.0 21.1 0.00023 21.3 0.0 22.6 22 0 0 22 22 22 21 Ankyrin repeat Ank_5 PF13857.6 GAM34809.1 - 2e-68 225.5 35.1 5.5e-06 26.6 0.3 19.0 5 3 13 19 19 19 17 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 GAM34809.1 - 2e-12 46.9 0.4 1.5e-11 44.0 0.4 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.6 GAM34809.1 - 1.8e-06 28.3 0.0 4.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 GAM34809.1 - 1.9e-06 27.9 0.0 3.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain MmcB-like PF06319.12 GAM34809.1 - 0.95 9.1 4.0 67 3.1 0.0 5.5 7 1 1 8 8 8 0 DNA repair protein MmcB-like TMEM52 PF14979.6 GAM34810.1 - 0.034 14.1 0.8 0.061 13.2 0.8 1.4 1 0 0 1 1 1 0 Transmembrane 52 Ank_2 PF12796.7 GAM34811.1 - 3.1e-83 274.4 10.7 7.2e-12 45.7 0.0 12.1 9 3 3 12 12 12 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM34811.1 - 9.5e-69 227.0 18.3 4.4e-10 39.9 0.0 15.2 11 6 5 16 16 16 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM34811.1 - 6e-65 207.5 20.3 5.4e-05 23.3 0.0 18.5 19 1 1 20 20 20 12 Ankyrin repeat Ank PF00023.30 GAM34811.1 - 2.1e-60 198.7 28.4 1.3e-05 25.5 0.0 19.1 19 1 1 20 20 20 13 Ankyrin repeat Ank_5 PF13857.6 GAM34811.1 - 1.7e-50 168.4 9.7 2.4e-07 30.9 0.0 12.2 12 1 1 13 13 13 9 Ankyrin repeats (many copies) DUF3447 PF11929.8 GAM34811.1 - 0.026 14.5 0.0 13 5.9 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) AAA_9 PF12781.7 GAM34811.1 - 0.12 11.5 0.0 0.29 10.2 0.0 1.6 1 0 0 1 1 1 0 ATP-binding dynein motor region VWA_3_C PF18571.1 GAM34811.1 - 0.13 12.1 0.3 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain Glyco_hydro_cc PF11790.8 GAM34812.1 - 1.5e-58 198.2 7.2 1.7e-58 198.0 7.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Dicty_CAR PF05462.11 GAM34814.1 - 4.9e-14 52.2 12.6 7.6e-14 51.5 12.6 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.8 GAM34814.1 - 7e-10 39.0 18.4 9.6e-10 38.6 18.4 1.1 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 GAM34814.1 - 7.1e-08 32.1 4.7 7.6e-08 32.0 4.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.17 GAM34814.1 - 0.0004 19.5 17.6 0.024 13.7 17.6 2.1 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7TM_GPCR_Srsx PF10320.9 GAM34814.1 - 0.0053 16.2 14.4 0.0081 15.6 14.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx WBP-1 PF11669.8 GAM34814.1 - 0.13 12.9 0.5 0.64 10.7 0.0 2.3 3 0 0 3 3 3 0 WW domain-binding protein 1 adh_short PF00106.25 GAM34815.1 - 6e-25 87.8 0.0 6.3e-21 74.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM34815.1 - 1.9e-13 50.5 0.0 8.1e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_2 PF03446.15 GAM34815.1 - 0.028 14.6 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 GAM34815.1 - 0.051 13.6 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YjeF_N PF03853.15 GAM34815.1 - 0.072 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 GAM34815.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NLE PF08154.12 GAM34815.1 - 0.16 12.5 0.1 1.4 9.5 0.0 2.2 2 0 0 2 2 2 0 NLE (NUC135) domain DIOX_N PF14226.6 GAM34816.1 - 9.5e-21 74.7 0.3 1.8e-20 73.9 0.3 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM34816.1 - 4e-12 46.5 0.1 1e-11 45.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DSBA PF01323.20 GAM34817.1 - 4.2e-30 105.0 0.0 5.2e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 GAM34817.1 - 0.037 14.1 0.0 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain GRAS PF03514.14 GAM34817.1 - 0.18 10.7 0.0 0.3 10.0 0.0 1.3 2 0 0 2 2 2 0 GRAS domain family NAD_binding_10 PF13460.6 GAM34818.1 - 1.6e-18 67.2 0.0 3.1e-18 66.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM34818.1 - 7.9e-09 35.3 0.0 1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAM34818.1 - 6e-07 29.3 0.0 8.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family PAC2 PF09754.9 GAM34818.1 - 0.083 12.9 0.0 0.091 12.8 0.0 1.2 1 0 0 1 1 1 0 PAC2 family NmrA PF05368.13 GAM34819.1 - 9e-20 71.2 0.0 1.2e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM34819.1 - 1.3e-16 61.0 0.0 3.3e-16 59.7 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 GAM34819.1 - 2.3e-08 34.2 0.0 4.6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAM34819.1 - 7.3e-07 29.5 0.2 4.4e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 GAM34819.1 - 0.00054 20.2 0.1 0.00099 19.4 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 GAM34819.1 - 0.0015 19.0 1.3 0.003 18.1 0.2 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 GAM34819.1 - 0.0031 17.0 0.1 0.031 13.7 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 GAM34819.1 - 0.0033 17.3 0.1 0.0063 16.4 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAM34819.1 - 0.0038 17.4 0.0 0.0068 16.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 GAM34819.1 - 0.0094 16.4 0.2 0.069 13.6 0.1 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 GAM34819.1 - 0.095 12.1 0.0 0.26 10.6 0.0 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Bac_luciferase PF00296.20 GAM34820.1 - 4.9e-56 190.4 0.0 7.7e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1275 PF06912.11 GAM34821.1 - 1.5e-44 152.2 10.6 2e-44 151.8 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) LIP PF03583.14 GAM34822.1 - 3e-08 33.4 0.1 0.0059 16.0 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_6 PF12697.7 GAM34822.1 - 1.5e-07 32.3 0.7 2.3e-07 31.7 0.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM34822.1 - 6.2e-06 25.7 0.1 0.0018 17.6 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAM34822.1 - 0.00028 20.4 0.1 0.28 10.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAM34822.1 - 0.004 16.9 0.1 0.023 14.4 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold BLIP PF07467.11 GAM34822.1 - 0.032 14.9 0.7 0.15 12.7 0.1 2.1 2 0 0 2 2 2 0 Beta-lactamase inhibitor (BLIP) Glyco_hydro_3_C PF01915.22 GAM34823.1 - 8.5e-54 182.6 0.0 1.5e-53 181.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Peroxidase_2 PF01328.17 GAM34823.1 - 7.9e-49 166.7 0.0 1.4e-48 165.9 0.0 1.4 1 0 0 1 1 1 1 Peroxidase, family 2 Glyco_hydro_3 PF00933.21 GAM34823.1 - 6.6e-33 114.4 0.0 4.1e-30 105.3 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM34823.1 - 1.2e-16 60.5 0.2 2.3e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PTR2 PF00854.21 GAM34824.1 - 4.6e-55 187.1 8.4 6e-55 186.7 8.4 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 GAM34824.1 - 3.3e-07 29.6 30.4 1.3e-06 27.6 30.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 GAM34824.1 - 0.016 15.2 0.1 0.016 15.2 0.1 3.7 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III adh_short_C2 PF13561.6 GAM34826.1 - 1.6e-54 184.9 0.7 2e-54 184.6 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM34826.1 - 1.8e-42 145.0 0.5 2.2e-42 144.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM34826.1 - 1.9e-12 47.4 0.3 3e-12 46.8 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM34826.1 - 4.6e-05 23.0 0.1 7.9e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM34826.1 - 0.00034 20.1 0.1 0.00046 19.7 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_2 PF03446.15 GAM34826.1 - 0.0094 16.1 0.2 0.029 14.6 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase GCP_N_terminal PF17681.1 GAM34827.1 - 9.4e-34 117.4 0.1 3.1e-33 115.7 0.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 GAM34827.1 - 2.3e-25 89.7 0.1 4.4e-25 88.8 0.1 1.4 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal DUF3613 PF12266.8 GAM34827.1 - 0.59 10.0 3.8 0.28 11.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) ThiF PF00899.21 GAM34828.1 - 2e-114 381.0 0.0 1.1e-75 254.1 0.0 2.4 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 GAM34828.1 - 6.1e-99 331.0 0.1 4.4e-97 324.9 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 GAM34828.1 - 3.4e-31 107.8 0.1 7.2e-31 106.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 GAM34828.1 - 2.2e-30 104.6 0.2 4.5e-30 103.7 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 GAM34828.1 - 9.5e-25 86.6 2.0 2.4e-24 85.3 1.5 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 GAM34828.1 - 0.082 13.4 0.3 1.3 9.5 0.0 3.1 5 0 0 5 5 5 0 Putative NAD(P)-binding Methyltransf_25 PF13649.6 GAM34829.1 - 1e-07 32.5 0.0 3.4e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM34829.1 - 3.9e-07 30.0 0.0 9.2e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAM34829.1 - 1.4e-05 25.0 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 GAM34829.1 - 0.00025 20.9 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM34829.1 - 0.00028 20.3 0.0 0.0013 18.2 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 GAM34829.1 - 0.00064 20.7 0.0 0.0016 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAM34829.1 - 0.0065 15.8 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 GAM34829.1 - 0.0076 17.0 0.0 0.021 15.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM34829.1 - 0.025 15.2 0.0 0.084 13.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Fibrillarin PF01269.17 GAM34829.1 - 0.028 13.5 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Methyltransf_3 PF01596.17 GAM34829.1 - 0.046 12.9 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_16 PF10294.9 GAM34829.1 - 0.061 13.1 0.1 0.96 9.2 0.1 2.5 2 1 0 2 2 2 0 Lysine methyltransferase MetW PF07021.12 GAM34829.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 GAM34829.1 - 0.17 10.9 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 GAM34829.1 - 0.19 11.9 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase GST_N_2 PF13409.6 GAM34830.1 - 7.9e-23 80.5 0.2 2.2e-22 79.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM34830.1 - 5.4e-15 55.2 0.0 1.1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM34830.1 - 7.7e-07 29.2 0.1 1.5e-06 28.3 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM34830.1 - 4.7e-06 26.9 0.1 0.00013 22.3 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM34830.1 - 0.00021 21.4 0.2 0.00047 20.3 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.27 GAM34831.1 - 1.3e-66 220.6 5.7 9.4e-24 83.2 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 GAM34831.1 - 2.9e-18 64.0 10.5 0.00012 21.3 0.0 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 GAM34831.1 - 5.4e-18 63.3 4.9 3.9e-05 23.3 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 GAM34831.1 - 1.7e-17 63.6 2.3 5.4e-10 39.6 0.3 3.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAM34831.1 - 1.9e-12 46.1 12.0 0.00041 19.7 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 GAM34831.1 - 2.2e-10 40.2 0.3 7.2e-05 22.5 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAM34831.1 - 7.6e-05 23.0 0.0 0.00088 19.6 0.1 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 GAM34831.1 - 0.00066 19.5 0.3 0.65 9.9 0.0 2.7 3 0 0 3 3 3 2 EF hand Cyclin_C_2 PF16899.5 GAM34832.1 - 0.049 14.0 1.3 0.059 13.8 0.2 1.7 2 0 0 2 2 2 0 Cyclin C-terminal domain SNARE PF05739.19 GAM34833.1 - 3.9e-09 36.4 1.9 3.9e-09 36.4 1.9 1.6 2 0 0 2 2 2 1 SNARE domain XhlA PF10779.9 GAM34833.1 - 0.0095 16.1 2.5 0.0095 16.1 2.5 3.0 3 1 0 3 3 3 1 Haemolysin XhlA Phage_connect_1 PF05135.13 GAM34833.1 - 0.011 16.3 0.1 0.028 14.9 0.1 1.6 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein Phage_GP20 PF06810.11 GAM34833.1 - 0.013 15.3 1.2 20 5.0 0.0 3.2 2 1 1 3 3 3 0 Phage minor structural protein GP20 HemX PF04375.14 GAM34833.1 - 0.035 13.4 4.1 1.2 8.4 0.9 2.2 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Med9 PF07544.13 GAM34833.1 - 0.054 13.6 4.2 1.3 9.2 0.2 3.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Use1 PF09753.9 GAM34833.1 - 0.058 13.1 0.6 0.1 12.3 0.6 1.8 1 1 0 1 1 1 0 Membrane fusion protein Use1 Synaptobrevin PF00957.21 GAM34833.1 - 0.067 13.0 1.1 0.46 10.3 0.1 2.4 2 0 0 2 2 2 0 Synaptobrevin FliJ PF02050.16 GAM34833.1 - 0.24 11.6 5.0 4.2 7.6 2.3 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein Fusion_gly PF00523.18 GAM34833.1 - 0.26 9.5 1.8 0.37 9.0 0.1 1.8 2 0 0 2 2 2 0 Fusion glycoprotein F0 FUSC-like PF12805.7 GAM34833.1 - 0.57 9.2 2.5 2 7.4 0.3 2.3 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS DFRP_C PF16543.5 GAM34834.1 - 3.1e-25 88.5 4.7 3.1e-25 88.5 4.7 3.5 3 1 0 3 3 2 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 GAM34834.1 - 8.1e-06 25.6 2.7 8.1e-06 25.6 2.7 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GAM34834.1 - 6.3e-05 23.6 11.4 0.001 19.7 5.3 3.5 3 1 0 3 3 3 1 Torus domain zf-TRAF PF02176.18 GAM34834.1 - 0.00013 22.6 11.4 0.0012 19.5 5.3 4.2 3 1 2 5 5 3 2 TRAF-type zinc finger zf_CCCH_4 PF18345.1 GAM34834.1 - 0.001 19.0 9.7 0.001 19.0 9.7 3.6 4 0 0 4 4 4 1 Zinc finger domain zf-TRAF_2 PF15965.5 GAM34834.1 - 0.0013 19.2 10.9 0.44 11.1 5.2 2.9 1 1 1 2 2 2 2 TRAF-like zinc-finger Cwf_Cwc_15 PF04889.12 GAM34834.1 - 0.0014 18.4 3.9 0.0014 18.4 3.9 3.2 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein zf-CCCH_4 PF18044.1 GAM34834.1 - 0.0023 17.7 3.7 0.0023 17.7 3.7 3.9 4 0 0 4 4 4 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 GAM34834.1 - 0.019 15.2 5.3 0.34 11.2 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger containing family zf-ACC PF17848.1 GAM34834.1 - 0.034 14.2 4.7 0.073 13.2 0.9 2.9 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-CCCH_2 PF14608.6 GAM34834.1 - 0.14 12.7 14.9 1.7 9.2 6.2 3.4 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-DNA_Pol PF08996.10 GAM34834.1 - 0.63 9.8 19.0 0.016 15.0 10.2 2.3 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger adh_short PF00106.25 GAM34835.1 - 2.2e-25 89.3 0.0 2.7e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM34835.1 - 3.5e-21 75.8 0.0 4.7e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM34835.1 - 2.7e-06 27.4 0.0 3.7e-06 27.0 0.0 1.3 1 1 0 1 1 1 1 KR domain DUF460 PF04312.13 GAM34835.1 - 0.054 13.2 0.2 0.075 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) NMU PF02070.15 GAM34835.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Neuromedin U NmrA PF05368.13 GAM34835.1 - 0.088 12.4 0.6 0.32 10.5 0.1 1.9 2 0 0 2 2 2 0 NmrA-like family DUF1776 PF08643.10 GAM34835.1 - 0.094 12.1 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) WD40 PF00400.32 GAM34837.1 - 0.12 13.2 0.4 0.82 10.6 0.1 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat 2OG-FeII_Oxy_2 PF13532.6 GAM34838.1 - 1.4e-12 48.2 0.0 2.9e-12 47.2 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 GAM34839.1 - 3.2e-28 98.7 22.2 3.2e-28 98.7 22.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily GILT PF03227.16 GAM34841.1 - 3.3e-13 49.8 0.6 3.3e-13 49.8 0.6 2.0 2 1 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Fungal_trans PF04082.18 GAM34842.1 - 2.2e-20 72.8 0.2 3.6e-20 72.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_1 PF01979.20 GAM34843.1 - 6.5e-47 160.5 0.0 8.4e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM34843.1 - 1.7e-19 70.6 0.3 8.6e-13 48.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.16 GAM34844.1 - 8.4e-34 117.0 33.5 8.4e-34 117.0 33.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM34844.1 - 3.5e-05 23.3 10.7 0.00048 19.5 3.5 2.4 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Hexokinase_1 PF00349.21 GAM34845.1 - 2.1e-62 210.6 0.0 3.1e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 GAM34845.1 - 1.9e-45 155.1 0.0 2.7e-44 151.4 0.0 2.1 1 1 0 1 1 1 1 Hexokinase OAD_gamma PF04277.13 GAM34845.1 - 0.25 12.0 1.1 0.63 10.7 1.1 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Stm1_N PF09598.10 GAM34845.1 - 7.8 7.4 11.5 13 6.7 0.1 2.8 2 0 0 2 2 2 0 Stm1 TFIIA_gamma_N PF02268.16 GAM34846.1 - 1.7e-21 75.9 2.1 2e-21 75.7 0.4 2.0 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 GAM34846.1 - 1.1e-20 73.5 2.4 2.4e-20 72.4 2.4 1.6 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TPR_12 PF13424.6 GAM34847.1 - 2.9e-11 43.5 9.7 1.1e-05 25.6 0.6 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAM34847.1 - 4.6e-07 29.5 7.0 0.03 14.2 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat SKG6 PF08693.10 GAM34847.1 - 0.0047 16.3 0.1 0.0047 16.3 0.1 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Rax2 PF12768.7 GAM34847.1 - 0.0063 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TPR_8 PF13181.6 GAM34847.1 - 0.043 14.0 1.0 13 6.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM34847.1 - 0.061 13.4 1.2 29 5.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Podoplanin PF05808.11 GAM34847.1 - 0.088 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Podoplanin TPR_2 PF07719.17 GAM34847.1 - 0.094 12.9 6.9 6.3 7.2 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM34847.1 - 0.31 10.4 4.4 3.7 6.8 3.8 2.4 1 1 0 1 1 1 0 MalT-like TPR region DUF92 PF01940.16 GAM34848.1 - 9.2e-87 290.4 12.0 1.1e-86 290.1 12.0 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Aldedh PF00171.22 GAM34850.1 - 3.2e-129 431.5 0.0 3.5e-129 431.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAM34850.1 - 6.5e-07 28.7 0.0 1.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 GAM34850.1 - 0.0021 17.6 0.0 0.016 14.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Methyltransf_33 PF10017.9 GAM34851.1 - 2.3e-87 293.0 0.0 3.2e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 GAM34851.1 - 1.4e-22 80.5 3.7 2.6e-22 79.6 3.7 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 GAM34851.1 - 1.4e-06 28.8 4.9 1.7e-05 25.3 0.9 3.3 2 1 1 3 3 3 1 DinB superfamily Radical_SAM PF04055.21 GAM34852.1 - 4.2e-11 43.5 0.0 6.4e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 GAM34852.1 - 0.00022 21.5 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 GAM34852.1 - 0.059 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain Frankia_peptide PF14407.6 GAM34852.1 - 0.12 12.4 0.0 8.9 6.4 0.0 2.6 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. KSHV_K8 PF07188.11 GAM34852.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein Fungal_trans PF04082.18 GAM34853.1 - 1.9e-31 109.1 0.0 4e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNA_pol PF00940.19 GAM34854.1 - 1.4e-182 607.2 0.0 2.7e-182 606.2 0.0 1.5 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 GAM34854.1 - 7e-88 295.2 0.1 1.1e-87 294.6 0.1 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Gemini_AL3 PF01407.17 GAM34854.1 - 0.013 15.3 0.0 0.64 9.9 0.0 2.4 2 0 0 2 2 2 0 Geminivirus AL3 protein HHH PF00633.23 GAM34854.1 - 0.13 12.2 0.0 0.42 10.6 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Sin_N PF04801.13 GAM34855.1 - 4e-23 82.3 0.0 7.9e-23 81.4 0.0 1.4 1 1 0 1 1 1 1 Sin-like protein conserved region NIR_SIR PF01077.22 GAM34856.1 - 2e-52 176.9 0.0 9.4e-46 155.2 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 GAM34856.1 - 5.5e-31 106.2 0.0 7.8e-15 54.5 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 GAM34856.1 - 8.9e-14 51.9 0.0 1.4e-11 44.8 0.0 2.6 1 1 1 2 2 2 2 Flavodoxin POR_N PF01855.19 GAM34856.1 - 6.2e-07 29.4 0.0 1.6e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.11 GAM34857.1 - 5.3e-67 225.4 0.4 6.8e-67 225.0 0.4 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 SPC12 PF06645.13 GAM34857.1 - 0.028 14.5 0.9 0.028 14.5 0.9 2.0 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Ras PF00071.22 GAM34858.1 - 1.8e-59 200.0 0.3 2.3e-59 199.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM34858.1 - 3.6e-37 127.2 0.1 6e-37 126.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM34858.1 - 1.1e-17 64.0 0.2 1.4e-17 63.7 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAM34858.1 - 7.4e-06 25.5 0.0 1e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GAM34858.1 - 7.8e-06 25.6 0.1 4.9e-05 22.9 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM34858.1 - 1.6e-05 24.9 0.0 2.5e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAM34858.1 - 5.1e-05 22.7 0.2 6.3e-05 22.4 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAM34858.1 - 0.00011 22.2 0.1 0.096 12.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase TIR_2 PF13676.6 GAM34858.1 - 0.091 13.4 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 TIR domain AAA_7 PF12775.7 GAM34858.1 - 0.094 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP-synt_C PF00137.21 GAM34859.1 - 2.3e-22 79.1 37.1 2.4e-14 53.4 12.2 2.8 3 0 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 GAM34859.1 - 0.073 12.4 1.2 0.31 10.3 0.0 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Phage_holin_2_1 PF04971.12 GAM34859.1 - 0.23 11.5 0.1 0.23 11.5 0.1 2.4 2 1 0 2 2 2 0 Bacteriophage P21 holin S MIG-14_Wnt-bd PF06664.12 GAM34859.1 - 1.1 8.5 5.2 0.22 10.7 1.0 1.8 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Oxidored_q2 PF00420.24 GAM34859.1 - 3.7 7.2 11.5 0.85 9.3 2.0 3.4 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MoCF_biosynth PF00994.24 GAM34860.1 - 1.9e-49 167.0 0.0 1.6e-24 86.2 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 GAM34860.1 - 2e-40 138.1 1.5 3.7e-40 137.3 1.5 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 GAM34860.1 - 7.4e-18 64.5 0.1 1.7e-17 63.3 0.1 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Hydin_ADK PF17213.3 GAM34860.1 - 0.012 15.9 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain SelP_N PF04592.14 GAM34860.1 - 0.26 10.6 18.0 0.41 10.0 18.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DDHD PF02862.17 GAM34861.1 - 4.7e-26 92.3 0.0 1.1e-23 84.6 0.0 2.6 1 1 0 1 1 1 1 DDHD domain Abhydrolase_6 PF12697.7 GAM34861.1 - 0.0048 17.5 0.3 0.018 15.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family FAD_binding_3 PF01494.19 GAM34863.1 - 6.6e-70 236.1 0.0 8.2e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAM34863.1 - 4.6e-37 127.6 0.0 8.3e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 GAM34863.1 - 0.00031 20.4 0.0 0.029 13.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM34863.1 - 0.0012 18.2 0.0 0.039 13.2 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM34863.1 - 0.036 14.6 0.0 0.14 12.8 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM34863.1 - 0.06 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 GAM34863.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 GAM34863.1 - 0.14 11.7 0.0 0.39 10.3 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF866 PF05907.13 GAM34864.1 - 1.5e-61 206.9 0.1 2.1e-61 206.4 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) LSM PF01423.22 GAM34864.1 - 1.2e-17 63.3 0.2 2e-17 62.6 0.2 1.3 1 0 0 1 1 1 1 LSM domain HalOD2 PF18547.1 GAM34864.1 - 0.063 13.2 1.6 0.19 11.6 1.6 1.9 1 1 0 1 1 1 0 Halobacterial output domain 2 RPA43_OB PF17875.1 GAM34864.1 - 0.14 12.8 0.0 0.23 12.1 0.0 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DUF4379 PF14311.6 GAM34864.1 - 0.21 12.0 2.7 0.21 12.0 0.6 2.1 1 1 1 2 2 2 0 Probable Zinc-ribbon domain Methyltransf_11 PF08241.12 GAM34865.1 - 1.4e-16 60.9 0.0 2.6e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM34865.1 - 7.2e-16 58.3 0.0 9.9e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM34865.1 - 1.1e-15 58.1 0.1 2.3e-15 57.1 0.1 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM34865.1 - 1.5e-13 50.9 0.0 2.2e-13 50.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAM34865.1 - 2e-13 50.3 0.0 2.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 GAM34865.1 - 1.4e-11 44.9 0.0 2.5e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM34865.1 - 1.2e-07 31.3 0.0 1e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 GAM34865.1 - 3.1e-06 27.2 0.0 4.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM34865.1 - 1.6e-05 24.5 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 GAM34865.1 - 9.3e-05 21.5 0.0 0.00013 21.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 GAM34865.1 - 0.00015 21.6 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 GAM34865.1 - 0.00027 20.6 0.0 0.00044 19.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 GAM34865.1 - 0.00032 20.6 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 GAM34865.1 - 0.00051 19.6 0.0 0.0006 19.4 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase ADH_zinc_N PF00107.26 GAM34865.1 - 0.0012 18.8 0.1 0.0051 16.8 0.1 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase PrmA PF06325.13 GAM34865.1 - 0.0026 17.2 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.13 GAM34865.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_2 PF00891.18 GAM34865.1 - 0.027 13.8 0.0 0.051 12.9 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain Met_10 PF02475.16 GAM34865.1 - 0.064 13.0 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein NodS PF05401.11 GAM34865.1 - 0.18 11.4 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DASH_Dad1 PF08649.10 GAM34866.1 - 3.9e-06 27.0 1.0 7.2e-06 26.1 1.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad1 Spore_III_AF PF09581.10 GAM34866.1 - 0.11 12.5 2.0 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) FYDLN_acid PF09538.10 GAM34866.1 - 0.52 11.0 8.3 0.22 12.2 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Spt20 PF12090.8 GAM34866.1 - 2 7.9 8.8 3.5 7.2 8.8 1.4 1 0 0 1 1 1 0 Spt20 family ORC_WH_C PF18137.1 GAM34866.1 - 4.6 7.3 9.2 4.6 7.3 8.0 1.5 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Ras PF00071.22 GAM34867.1 - 7.8e-49 165.4 0.0 9.9e-49 165.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM34867.1 - 2.4e-20 72.9 0.0 3.9e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM34867.1 - 5.4e-05 22.7 0.0 0.00012 21.6 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 GAM34867.1 - 0.023 14.2 0.1 0.039 13.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 GAM34867.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PAP2 PF01569.21 GAM34868.1 - 4.8e-18 65.2 3.3 1.6e-17 63.6 3.3 1.8 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 GAM34868.1 - 0.0004 20.1 2.9 0.0011 18.7 2.9 1.8 1 0 0 1 1 1 1 PAP2 superfamily Peptidase_C48 PF02902.19 GAM34869.1 - 6e-27 94.9 0.0 9.9e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Glyco_hydro_16 PF00722.21 GAM34870.1 - 0.0038 16.7 0.0 0.009 15.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Prefoldin PF02996.17 GAM34871.1 - 3.3e-05 23.8 3.3 0.0031 17.4 0.6 3.6 3 1 3 6 6 5 2 Prefoldin subunit CENP-F_leu_zip PF10473.9 GAM34871.1 - 5.5e-05 23.2 3.0 5.5e-05 23.2 3.0 2.9 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 GAM34871.1 - 6.9e-05 21.9 5.6 0.00023 20.2 5.1 1.8 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.12 GAM34871.1 - 0.00016 21.7 7.4 0.0037 17.3 3.6 3.2 2 1 2 4 4 3 2 Protein of unknown function (DUF1664) WEMBL PF05701.11 GAM34871.1 - 0.0003 19.6 1.0 0.00042 19.1 1.0 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light FlaC_arch PF05377.11 GAM34871.1 - 0.00032 21.0 3.7 0.33 11.4 0.2 3.7 2 1 2 4 4 3 1 Flagella accessory protein C (FlaC) DUF3294 PF07957.11 GAM34871.1 - 0.00056 19.7 0.1 0.0009 19.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) LPP PF04728.13 GAM34871.1 - 0.0013 19.1 9.3 0.57 10.6 0.5 4.4 3 1 2 5 5 3 1 Lipoprotein leucine-zipper ADIP PF11559.8 GAM34871.1 - 0.0014 18.7 8.3 0.016 15.3 3.5 2.0 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding KASH_CCD PF14662.6 GAM34871.1 - 0.0016 18.3 7.5 0.0036 17.2 5.7 2.1 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH AAA_13 PF13166.6 GAM34871.1 - 0.0016 17.2 2.9 0.0022 16.7 2.9 1.1 1 0 0 1 1 1 1 AAA domain GAS PF13851.6 GAM34871.1 - 0.0034 16.7 1.5 0.0069 15.8 1.5 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 GAM34871.1 - 0.0037 17.8 1.3 0.0096 16.4 1.3 1.8 1 0 0 1 1 1 1 Apg6 coiled-coil region ATG16 PF08614.11 GAM34871.1 - 0.0042 17.3 6.2 0.012 15.9 6.2 1.7 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) BRE1 PF08647.11 GAM34871.1 - 0.0042 17.1 2.3 0.0076 16.3 2.3 1.4 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase Leu_zip PF15294.6 GAM34871.1 - 0.0048 16.4 1.6 0.0077 15.8 1.6 1.2 1 0 0 1 1 1 1 Leucine zipper bZIP_1 PF00170.21 GAM34871.1 - 0.0062 16.6 0.9 0.57 10.3 0.1 3.0 2 1 0 3 3 2 1 bZIP transcription factor Fib_alpha PF08702.10 GAM34871.1 - 0.0064 16.7 6.3 0.011 15.9 4.8 2.0 1 1 0 2 2 1 1 Fibrinogen alpha/beta chain family DivIC PF04977.15 GAM34871.1 - 0.0065 16.2 11.9 2.2 8.1 0.3 4.2 3 1 2 5 5 5 0 Septum formation initiator SseC PF04888.12 GAM34871.1 - 0.0077 15.9 0.2 0.014 15.0 0.2 1.4 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family DUF641 PF04859.12 GAM34871.1 - 0.0096 16.3 6.2 1.1 9.6 1.0 2.6 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) DUF2968 PF11180.8 GAM34871.1 - 0.0097 15.6 7.4 0.02 14.5 7.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Spc24 PF08286.11 GAM34871.1 - 0.012 15.9 4.7 1.7 8.9 0.5 2.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Atg14 PF10186.9 GAM34871.1 - 0.012 14.7 4.7 0.016 14.3 3.6 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 GAM34871.1 - 0.013 16.0 5.5 0.015 15.8 4.0 1.7 1 1 0 1 1 1 0 Fez1 YscO PF07321.12 GAM34871.1 - 0.014 15.4 5.2 0.046 13.7 3.3 2.3 1 1 1 2 2 2 0 Type III secretion protein YscO TSC22 PF01166.18 GAM34871.1 - 0.014 15.7 1.3 5 7.5 0.4 3.0 1 1 1 2 2 2 0 TSC-22/dip/bun family TPR_MLP1_2 PF07926.12 GAM34871.1 - 0.016 15.3 2.8 0.052 13.6 2.8 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2730 PF10805.8 GAM34871.1 - 0.016 15.3 3.0 0.33 11.1 1.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) TACC_C PF05010.14 GAM34871.1 - 0.018 14.8 1.1 0.028 14.2 1.1 1.4 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Baculo_PEP_C PF04513.12 GAM34871.1 - 0.018 15.1 12.3 0.032 14.3 10.1 2.5 3 1 0 3 3 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1640 PF07798.11 GAM34871.1 - 0.021 14.9 9.7 0.077 13.0 3.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1640) BLOC1_2 PF10046.9 GAM34871.1 - 0.021 15.1 4.1 0.2 12.0 2.2 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4618 PF15397.6 GAM34871.1 - 0.022 14.2 7.6 1.1 8.6 1.0 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) Prominin PF05478.11 GAM34871.1 - 0.029 12.4 2.4 0.042 11.8 2.4 1.1 1 0 0 1 1 1 0 Prominin Rootletin PF15035.6 GAM34871.1 - 0.031 14.3 6.1 0.13 12.2 6.2 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4200 PF13863.6 GAM34871.1 - 0.031 14.7 2.2 0.17 12.3 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Prefoldin_2 PF01920.20 GAM34871.1 - 0.033 14.1 2.9 6.7 6.7 1.1 3.2 2 1 1 3 3 2 0 Prefoldin subunit DUF3450 PF11932.8 GAM34871.1 - 0.037 13.3 3.3 0.061 12.6 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) THOC7 PF05615.13 GAM34871.1 - 0.037 14.3 2.9 0.067 13.5 2.2 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 MscS_porin PF12795.7 GAM34871.1 - 0.038 13.5 9.4 0.061 12.9 9.4 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain HAP1_N PF04849.13 GAM34871.1 - 0.046 12.9 3.1 0.076 12.2 3.1 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Cep57_CLD_2 PF14197.6 GAM34871.1 - 0.047 13.8 0.8 0.047 13.8 0.8 2.6 2 1 1 3 3 1 0 Centrosome localisation domain of PPC89 COG7 PF10191.9 GAM34871.1 - 0.048 11.9 3.2 0.63 8.2 1.7 2.0 1 1 2 3 3 3 0 Golgi complex component 7 (COG7) AIP3 PF03915.13 GAM34871.1 - 0.051 12.7 4.7 0.57 9.2 4.1 2.1 2 0 0 2 2 2 0 Actin interacting protein 3 DUF4795 PF16043.5 GAM34871.1 - 0.056 13.0 3.3 0.45 10.1 3.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) YabA PF06156.13 GAM34871.1 - 0.058 14.0 4.7 0.19 12.4 2.5 2.7 1 1 2 3 3 2 0 Initiation control protein YabA WXG100 PF06013.12 GAM34871.1 - 0.059 13.6 3.4 5.6 7.3 0.1 3.9 2 1 3 5 5 5 0 Proteins of 100 residues with WXG DUF677 PF05055.12 GAM34871.1 - 0.06 12.2 1.3 0.099 11.5 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF812 PF05667.11 GAM34871.1 - 0.064 12.1 4.7 0.3 9.9 4.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) HIP1_clath_bdg PF16515.5 GAM34871.1 - 0.065 13.8 5.0 2.1 9.0 3.3 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Mod_r PF07200.13 GAM34871.1 - 0.068 13.3 2.1 0.13 12.3 2.1 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF2353 PF09789.9 GAM34871.1 - 0.076 12.4 5.9 0.44 9.8 6.0 2.0 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) HAUS-augmin3 PF14932.6 GAM34871.1 - 0.079 12.5 3.0 0.16 11.6 3.0 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Filament PF00038.21 GAM34871.1 - 0.083 12.5 6.1 0.4 10.2 4.8 2.0 1 1 1 2 2 2 0 Intermediate filament protein DUF4763 PF15960.5 GAM34871.1 - 0.091 12.1 5.7 0.23 10.7 5.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) DegS PF05384.11 GAM34871.1 - 0.097 12.2 4.8 0.17 11.4 3.9 1.9 1 1 0 1 1 1 0 Sensor protein DegS UPF0242 PF06785.11 GAM34871.1 - 0.1 12.7 3.4 0.19 11.9 2.2 1.8 1 1 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus COG5 PF10392.9 GAM34871.1 - 0.1 12.8 4.9 1.5 9.0 0.3 3.2 1 1 2 3 3 3 0 Golgi transport complex subunit 5 NPV_P10 PF05531.12 GAM34871.1 - 0.11 13.0 8.7 1.6 9.2 2.1 3.2 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 GAM34871.1 - 0.11 12.3 3.2 0.71 9.7 3.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF713 PF05218.14 GAM34871.1 - 0.11 12.2 1.0 0.43 10.3 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF713) DUF4201 PF13870.6 GAM34871.1 - 0.12 12.2 3.9 0.15 11.8 2.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TMPIT PF07851.13 GAM34871.1 - 0.13 11.5 0.7 0.2 10.9 0.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein SOGA PF11365.8 GAM34871.1 - 0.13 13.4 1.0 0.76 10.9 0.6 2.4 1 1 1 2 2 2 0 Protein SOGA TMF_TATA_bd PF12325.8 GAM34871.1 - 0.15 12.3 6.8 0.27 11.5 3.8 2.4 2 1 0 2 2 1 0 TATA element modulatory factor 1 TATA binding JIP_LZII PF16471.5 GAM34871.1 - 0.15 12.2 2.6 4 7.7 0.5 3.0 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II Seryl_tRNA_N PF02403.22 GAM34871.1 - 0.15 12.3 5.1 0.069 13.4 1.1 2.1 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain DUF4472 PF14739.6 GAM34871.1 - 0.16 12.7 1.9 0.33 11.7 1.0 2.0 1 1 1 2 2 1 0 Domain of unknown function (DUF4472) Macoilin PF09726.9 GAM34871.1 - 0.17 10.4 3.7 0.29 9.6 3.7 1.4 1 0 0 1 1 1 0 Macoilin family PspA_IM30 PF04012.12 GAM34871.1 - 0.18 11.4 6.4 0.65 9.5 1.9 2.4 1 1 1 2 2 2 0 PspA/IM30 family Fungal_TACC PF12709.7 GAM34871.1 - 0.18 12.3 0.9 9.7 6.7 0.5 2.6 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF5082 PF16888.5 GAM34871.1 - 0.19 12.0 5.9 5.5 7.3 0.6 3.1 1 1 0 2 2 1 0 Domain of unknown function (DUF5082) Tup_N PF08581.10 GAM34871.1 - 0.19 12.0 2.7 9.9 6.5 0.4 2.7 1 1 0 2 2 2 0 Tup N-terminal Laminin_II PF06009.12 GAM34871.1 - 0.22 11.5 5.7 2.8 8.0 5.1 2.6 2 1 0 2 2 1 0 Laminin Domain II DUF2046 PF09755.9 GAM34871.1 - 0.26 10.5 6.1 2.5 7.2 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) TMF_DNA_bd PF12329.8 GAM34871.1 - 0.3 11.1 1.4 19 5.4 0.2 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding COG2 PF06148.11 GAM34871.1 - 0.3 11.2 4.5 0.43 10.7 0.7 2.6 1 1 2 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin_2 PF14523.6 GAM34871.1 - 0.38 11.2 8.3 0.93 9.9 7.2 2.2 2 1 0 2 2 1 0 Syntaxin-like protein Phlebovirus_NSM PF07246.11 GAM34871.1 - 0.39 10.1 3.7 0.77 9.1 3.6 1.5 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Baculo_F PF12259.8 GAM34871.1 - 0.43 9.0 5.2 0.18 10.3 1.3 1.9 1 1 1 2 2 2 0 Baculovirus F protein ZapB PF06005.12 GAM34871.1 - 0.48 10.9 5.9 5.4 7.5 5.1 2.6 1 1 1 2 2 2 0 Cell division protein ZapB Cnn_1N PF07989.11 GAM34871.1 - 0.5 10.6 3.2 5.7 7.2 3.2 2.6 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Lzipper-MIP1 PF14389.6 GAM34871.1 - 0.5 10.7 3.5 2.7 8.4 3.4 2.6 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Nup54 PF13874.6 GAM34871.1 - 0.52 10.4 5.7 1.4 9.0 5.7 1.8 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 HMMR_C PF15908.5 GAM34871.1 - 0.56 10.5 3.6 2.1 8.6 1.5 2.5 1 1 2 3 3 2 0 Hyaluronan mediated motility receptor C-terminal DUF948 PF06103.11 GAM34871.1 - 0.61 10.4 6.6 2.6 8.4 1.9 2.6 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) CLZ PF16526.5 GAM34871.1 - 0.7 10.3 6.2 4.6 7.7 1.6 3.5 1 1 4 5 5 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CALCOCO1 PF07888.11 GAM34871.1 - 0.73 8.6 7.9 2.2 7.0 7.9 1.6 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like FliJ PF02050.16 GAM34871.1 - 0.74 10.1 9.1 25 5.1 6.8 3.1 1 1 1 2 2 2 0 Flagellar FliJ protein DUF16 PF01519.16 GAM34871.1 - 1 9.9 8.3 8.9 6.9 8.3 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 FAM76 PF16046.5 GAM34871.1 - 1.3 8.3 4.9 10 5.4 1.5 2.2 1 1 1 2 2 2 0 FAM76 protein HrpB7 PF09486.10 GAM34871.1 - 1.3 9.3 6.8 0.91 9.9 2.8 2.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) SlyX PF04102.12 GAM34871.1 - 2.1 9.0 8.9 5.1 7.8 5.6 2.9 2 1 0 2 2 2 0 SlyX F_actin_bind PF08919.10 GAM34871.1 - 2.2 8.4 7.3 22 5.2 4.9 3.2 2 1 0 2 2 1 0 F-actin binding TolA_bind_tri PF16331.5 GAM34871.1 - 2.9 8.0 9.9 14 5.8 0.4 3.1 2 1 1 3 3 2 0 TolA binding protein trimerisation Snapin_Pallidin PF14712.6 GAM34871.1 - 3.9 8.0 7.1 73 3.9 6.6 2.9 2 1 1 3 3 2 0 Snapin/Pallidin DUF3573 PF12097.8 GAM34871.1 - 5 5.9 4.9 20 3.9 4.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4094 PF13334.6 GAM34871.1 - 6.6 7.2 7.0 14 6.1 3.1 3.3 2 1 1 3 3 2 0 Domain of unknown function (DUF4094) polyprenyl_synt PF00348.17 GAM34872.1 - 1.2e-52 178.5 0.0 7.5e-52 175.9 0.0 2.0 2 0 0 2 2 2 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 GAM34872.1 - 0.00012 21.5 0.0 0.036 13.4 0.0 2.2 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain p450 PF00067.22 GAM34873.1 - 5.2e-116 388.1 0.0 1.3e-64 218.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Clusterin PF01093.17 GAM34873.1 - 0.045 12.8 0.5 0.089 11.8 0.5 1.4 1 0 0 1 1 1 0 Clusterin COX7B PF05392.11 GAM34873.1 - 0.051 13.2 0.4 38 4.1 0.0 3.6 3 0 0 3 3 3 0 Cytochrome C oxidase chain VIIB Cut12 PF11500.8 GAM34873.1 - 0.22 11.5 2.6 0.11 12.5 0.2 1.6 2 0 0 2 2 2 0 Spindle pole body formation-associated protein Transferase PF02458.15 GAM34874.1 - 2.8e-26 92.2 0.0 5e-26 91.3 0.0 1.4 1 1 0 1 1 1 1 Transferase family zf-HIT PF04438.16 GAM34875.1 - 1.5e-10 40.7 10.4 2.4e-10 40.1 10.4 1.3 1 0 0 1 1 1 1 HIT zinc finger CBFB_NFYA PF02045.15 GAM34875.1 - 0.24 12.0 2.6 0.48 11.1 0.3 2.3 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B zf-MYND PF01753.18 GAM34875.1 - 0.59 10.3 7.2 1.2 9.3 7.2 1.5 1 0 0 1 1 1 0 MYND finger TFIIF_alpha PF05793.12 GAM34875.1 - 1.1 7.8 15.9 2.2 6.8 15.9 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bac_luciferase PF00296.20 GAM34877.1 - 2.8e-48 165.0 2.3 3.6e-48 164.6 2.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Amidohydro_2 PF04909.14 GAM34877.1 - 0.061 13.1 0.3 0.76 9.5 0.0 2.5 2 1 1 3 3 3 0 Amidohydrolase Radical_SAM_N PF08497.10 GAM34877.1 - 0.064 12.5 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal DUF442 PF04273.13 GAM34878.1 - 0.083 13.0 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Putative phosphatase (DUF442) HNH_2 PF13391.6 GAM34880.1 - 2.7e-05 24.2 0.6 7.5e-05 22.8 0.6 1.7 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 GAM34880.1 - 0.11 12.7 0.6 0.86 9.8 0.6 2.3 1 1 0 1 1 1 0 HNH endonuclease EVE PF01878.18 GAM34881.1 - 0.061 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 EVE domain AAA_12 PF13087.6 GAM34882.1 - 1.3e-33 116.3 0.0 2.9e-33 115.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAM34882.1 - 2e-17 63.8 0.0 4e-17 62.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAM34882.1 - 4.5e-05 23.8 0.0 0.00018 21.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM34882.1 - 0.00055 19.7 0.0 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 GAM34882.1 - 0.011 15.6 0.0 0.028 14.2 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Flavoprotein PF02441.19 GAM34883.1 - 4.6e-25 88.2 0.1 5.7e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein UbiD PF01977.16 GAM34884.1 - 4.4e-120 401.3 0.0 5.1e-120 401.0 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Fungal_trans PF04082.18 GAM34885.1 - 1.3e-09 37.4 0.1 2.3e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2637 PF10935.8 GAM34885.1 - 0.05 13.5 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2637) RRM_1 PF00076.22 GAM34886.1 - 9.9e-16 57.3 0.0 2.8e-15 55.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 GAM34886.1 - 2.7e-06 27.8 0.6 2.7e-06 27.8 0.6 2.6 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 GAM34886.1 - 0.00023 20.9 0.0 0.00042 20.1 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif Snf7 PF03357.21 GAM34887.1 - 2.2e-20 73.0 15.6 3.8e-20 72.2 13.3 1.9 1 1 1 2 2 2 1 Snf7 Gon7 PF08738.10 GAM34887.1 - 0.0089 16.1 6.1 0.013 15.6 2.9 2.3 2 0 0 2 2 2 1 Gon7 family BMFP PF04380.13 GAM34887.1 - 0.15 12.5 10.2 1.1 9.8 1.4 4.2 3 1 0 4 4 4 0 Membrane fusogenic activity DUF2408 PF10303.9 GAM34887.1 - 0.93 10.1 7.0 0.74 10.4 5.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) TPR_MLP1_2 PF07926.12 GAM34887.1 - 1.5 8.9 19.4 0.041 14.0 8.4 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 GAM34887.1 - 4.4 7.5 14.3 11 6.3 8.9 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family WHIM1 PF15612.6 GAM34888.1 - 5.3e-07 29.0 0.0 1.3e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Nop14 PF04147.12 GAM34888.1 - 0.64 8.2 11.9 1.2 7.3 11.9 1.5 1 0 0 1 1 1 0 Nop14-like family DUF1770 PF08589.10 GAM34889.1 - 2.4e-30 105.4 1.5 3.6e-30 104.9 1.5 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PfkB PF00294.24 GAM34890.1 - 2.9e-75 253.4 0.1 3.3e-75 253.2 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 GAM34890.1 - 4.5e-05 23.0 0.0 0.00011 21.7 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DUF2700 PF10912.8 GAM34890.1 - 0.062 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) EST1_DNA_bind PF10373.9 GAM34891.1 - 8.1e-66 222.4 2.8 1.5e-65 221.5 0.2 2.3 2 1 1 3 3 3 1 Est1 DNA/RNA binding domain EST1 PF10374.9 GAM34891.1 - 1.6e-22 80.6 0.5 1.1e-21 78.0 0.3 2.4 2 0 0 2 2 2 1 Telomerase activating protein Est1 zf-C2H2 PF00096.26 GAM34892.1 - 0.013 15.9 13.0 0.91 10.1 0.4 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM34892.1 - 0.24 12.3 10.3 1.1 10.2 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger DUF629 PF04780.12 GAM34892.1 - 0.92 8.0 3.7 0.54 8.7 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Fungal_trans PF04082.18 GAM34893.1 - 5.6e-13 48.5 0.4 5.6e-13 48.5 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAM34893.1 - 5.2e-11 42.4 6.4 6.9e-05 23.1 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM34893.1 - 1.2e-07 31.9 7.6 0.0055 17.4 0.4 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAM34893.1 - 1.6e-05 25.1 0.6 0.19 12.0 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 GAM34893.1 - 0.011 16.2 2.9 0.045 14.2 0.9 2.4 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 GAM34893.1 - 0.014 15.3 5.7 1.3 9.1 0.4 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-met PF12874.7 GAM34893.1 - 0.02 15.3 2.4 5.3 7.6 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 GAM34893.1 - 0.053 13.5 5.9 1.7 8.8 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF536 PF04394.14 GAM34893.1 - 0.084 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF536 zf-BED PF02892.15 GAM34893.1 - 0.1 12.6 4.5 4.7 7.3 2.8 2.5 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 GAM34893.1 - 0.52 10.8 16.9 0.14 12.6 0.8 4.4 4 0 0 4 4 4 0 Zinc-finger double domain Pkinase PF00069.25 GAM34894.1 - 1.3e-68 231.3 0.0 2.1e-68 230.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM34894.1 - 4.5e-48 163.8 0.0 1.3e-47 162.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 GAM34894.1 - 3e-27 94.9 0.0 6.1e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 GAM34894.1 - 9.9e-16 57.9 0.0 2.4e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAM34894.1 - 2.6e-13 49.9 0.0 5.8e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 GAM34894.1 - 4.6e-09 36.0 0.0 2.1e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RA PF00788.23 GAM34894.1 - 0.0015 19.2 0.0 0.0025 18.4 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 GAM34894.1 - 0.0021 16.9 0.0 0.0044 15.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAM34894.1 - 0.043 13.2 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L5_C PF00673.21 GAM34895.1 - 1.9e-29 101.7 0.0 3e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 GAM34895.1 - 0.0004 20.7 0.0 0.00074 19.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 OapA_N PF08525.11 GAM34896.1 - 0.52 10.3 3.1 0.92 9.5 3.1 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif MFS_1 PF07690.16 GAM34897.1 - 4e-25 88.5 22.9 4e-25 88.5 22.9 1.6 1 1 0 2 2 2 1 Major Facilitator Superfamily UCH PF00443.29 GAM34897.1 - 3.5e-15 56.2 0.0 9.2e-15 54.8 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM34897.1 - 2.2e-13 50.5 0.0 1.6e-05 24.7 0.0 2.4 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Sugar_tr PF00083.24 GAM34897.1 - 0.034 13.0 31.4 1.4 7.6 31.4 2.6 1 1 0 1 1 1 0 Sugar (and other) transporter OATP PF03137.20 GAM34897.1 - 0.054 11.8 13.0 0.028 12.7 3.4 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF5336 PF17270.2 GAM34897.1 - 0.13 11.9 0.1 0.13 11.9 0.1 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF5336) EnY2 PF10163.9 GAM34897.1 - 0.15 12.4 0.0 0.91 9.9 0.0 2.2 2 0 0 2 2 2 0 Transcription factor e(y)2 Pep3_Vps18 PF05131.14 GAM34898.1 - 1e-43 148.7 0.5 5.9e-43 146.2 0.0 2.4 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 GAM34898.1 - 3.6e-09 36.6 8.2 6.6e-07 29.3 0.2 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS DUF2175 PF09943.9 GAM34898.1 - 0.00015 22.0 0.3 0.034 14.4 0.0 2.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) Zn_ribbon_17 PF17120.5 GAM34898.1 - 0.00031 20.3 0.1 0.00058 19.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 GAM34898.1 - 0.00043 20.2 0.3 0.00085 19.2 0.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_2 PF10367.9 GAM34898.1 - 0.00072 20.0 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 GAM34898.1 - 0.001 18.9 0.7 0.0022 17.8 0.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAM34898.1 - 0.0014 18.3 4.2 0.0029 17.3 4.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 GAM34898.1 - 0.004 17.5 0.9 0.0087 16.4 0.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAM34898.1 - 0.022 14.8 0.4 0.05 13.6 0.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 GAM34898.1 - 0.032 14.5 0.2 0.27 11.5 0.5 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 GAM34898.1 - 0.042 13.9 1.0 0.09 12.8 1.0 1.6 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4 PF00097.25 GAM34898.1 - 0.092 12.6 0.2 0.2 11.5 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_1 PF00515.28 GAM34898.1 - 0.42 10.5 1.8 11 6.0 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 GAM34899.1 - 3.2e-05 24.6 0.2 3.9e-05 24.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family His_Phos_2 PF00328.22 GAM34900.1 - 3.8e-05 23.2 0.0 5.3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) BAR PF03114.18 GAM34901.1 - 3.1e-47 161.3 8.8 4.1e-47 160.8 8.8 1.2 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 GAM34901.1 - 0.00036 19.7 2.9 0.00058 19.1 2.9 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking APG6_N PF17675.1 GAM34901.1 - 0.065 13.8 8.4 0.1 13.1 7.8 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region SNF2_N PF00176.23 GAM34902.1 - 1.4e-71 241.1 0.9 4.2e-71 239.5 0.9 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 GAM34902.1 - 9.2e-25 86.5 0.9 3.3e-24 84.7 0.8 2.1 1 1 1 2 2 2 1 Bromodomain Helicase_C PF00271.31 GAM34902.1 - 1.3e-19 70.6 0.1 1.1e-18 67.5 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.13 GAM34902.1 - 3.3e-16 59.4 14.7 3.3e-16 59.4 14.7 4.1 4 1 1 5 5 5 1 HSA SnAC PF14619.6 GAM34902.1 - 4.9e-14 52.7 3.4 4.9e-14 52.7 3.4 4.3 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 GAM34902.1 - 4.2e-10 39.9 0.0 4.2e-10 39.9 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit QLQ PF08880.11 GAM34902.1 - 6.2e-10 38.7 3.6 6.2e-10 38.7 3.6 2.2 2 0 0 2 2 2 1 QLQ EF-hand_14 PF17959.1 GAM34902.1 - 0.24 11.8 3.0 0.52 10.7 0.8 2.8 2 0 0 2 2 2 0 EF-hand domain Flavodoxin_1 PF00258.25 GAM34903.1 - 5.3e-33 114.2 0.0 1e-32 113.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 GAM34903.1 - 8.3e-30 104.0 0.0 1.4e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GAM34903.1 - 2.6e-14 53.8 0.1 2.7e-13 50.5 0.0 2.6 4 0 0 4 4 4 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 GAM34903.1 - 0.00053 19.7 0.0 0.016 14.9 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_5 PF12724.7 GAM34903.1 - 0.014 15.6 0.0 0.074 13.3 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain RNA_pol_3_Rpc31 PF11705.8 GAM34904.1 - 3.9e-57 194.1 19.4 5.5e-57 193.6 19.4 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Peripla_BP_3 PF13377.6 GAM34905.1 - 0.025 14.9 0.3 0.055 13.8 0.3 1.6 1 0 0 1 1 1 0 Periplasmic binding protein-like domain MitMem_reg PF13012.6 GAM34906.1 - 6.9e-09 36.1 0.3 1.6e-08 34.9 0.3 1.7 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAM34906.1 - 1.9e-07 31.1 0.0 3.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Solute_trans_a PF03619.16 GAM34907.1 - 6.4e-47 160.3 9.6 7.7e-47 160.0 9.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4492 PF14899.6 GAM34907.1 - 0.097 12.6 0.4 8.5 6.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) RTA1 PF04479.13 GAM34908.1 - 3.1e-58 196.8 15.1 3.1e-58 196.8 15.1 1.7 2 0 0 2 2 2 1 RTA1 like protein Orthoreo_P10 PF07204.11 GAM34908.1 - 0.0012 18.7 1.3 0.043 13.8 0.9 2.6 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 Zn_clus PF00172.18 GAM34909.1 - 6.8e-08 32.5 5.7 1.5e-07 31.4 5.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RSB_motif PF16294.5 GAM34910.1 - 1.6e-15 57.2 0.4 1.6e-15 57.2 0.4 3.8 2 1 2 4 4 4 1 RNSP1-SAP18 binding (RSB) motif SAP PF02037.27 GAM34910.1 - 4e-09 36.0 0.1 6.9e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 SAP domain Pinin_SDK_memA PF04696.13 GAM34910.1 - 0.35 10.9 0.0 0.35 10.9 0.0 2.8 2 1 1 3 3 3 0 pinin/SDK/memA/ protein conserved region ADH_zinc_N PF00107.26 GAM34911.1 - 1.8e-09 37.7 0.0 4.4e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM34911.1 - 4.4e-07 29.7 0.1 3.3e-06 26.9 0.1 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM34911.1 - 0.017 16.2 0.0 0.03 15.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1993 PF09351.10 GAM34912.1 - 2e-46 158.1 0.0 2.3e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) EVI2A PF05399.11 GAM34913.1 - 0.011 15.3 2.9 0.02 14.5 2.9 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Abhydrolase_1 PF00561.20 GAM34914.1 - 4.9e-50 170.6 0.0 1.4e-49 169.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM34914.1 - 0.00041 21.0 5.6 0.00096 19.8 5.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family THOC2_N PF16134.5 GAM34915.1 - 3.4e-238 792.4 0.0 5e-238 791.9 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 GAM34915.1 - 1.3e-105 352.9 0.2 2.8e-105 351.8 0.2 1.6 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 GAM34915.1 - 3.3e-29 100.8 0.1 2.8e-28 97.8 0.0 2.4 2 0 0 2 2 2 1 Transcription- and export-related complex subunit PAM2 PF07145.15 GAM34915.1 - 0.11 12.2 0.2 0.36 10.6 0.2 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region GST_C PF00043.25 GAM34916.1 - 5.1e-12 45.9 0.0 8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM34916.1 - 2.6e-06 27.5 0.0 5.3e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM34916.1 - 3.3e-05 23.8 0.0 5.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ctr PF04145.15 GAM34917.1 - 3.6e-40 138.0 0.1 3.6e-40 138.0 0.1 2.4 3 0 0 3 3 3 1 Ctr copper transporter family MFS_1 PF07690.16 GAM34918.1 - 2.8e-29 102.2 32.8 2.8e-29 102.2 32.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4418 PF14387.6 GAM34919.1 - 0.032 14.4 0.7 0.032 14.4 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) DUF4231 PF14015.6 GAM34919.1 - 7 7.2 5.9 1.1 9.7 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Pyr_redox_3 PF13738.6 GAM34920.1 - 2.5e-09 36.8 0.0 6.4e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAM34920.1 - 2.8e-06 26.1 0.0 5e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAM34920.1 - 3.9e-06 26.2 0.0 1.1e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 GAM34920.1 - 4.6e-06 26.1 0.0 0.00034 19.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF4863 PF16155.5 GAM34921.1 - 1.7e-67 226.0 0.0 2e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4863) MFS_1 PF07690.16 GAM34922.1 - 4.6e-35 121.2 25.2 4.6e-35 121.2 25.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM34922.1 - 5.9e-07 28.7 11.2 5.9e-07 28.7 11.2 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter BT1 PF03092.16 GAM34922.1 - 0.00021 19.6 0.6 0.00021 19.6 0.6 2.3 2 1 0 2 2 2 1 BT1 family DUF2530 PF10745.9 GAM34922.1 - 0.35 11.1 7.1 0.35 11.1 0.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) VCBS PF13517.6 GAM34923.1 - 3.8e-27 94.7 54.1 2.3e-12 47.3 5.4 8.1 4 3 5 9 9 9 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 GAM34923.1 - 2.6e-13 50.7 1.4 2.6e-13 50.7 1.4 2.6 4 0 0 4 4 4 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAM34923.1 - 3.1e-11 43.6 1.1 7e-11 42.5 0.3 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 GAM34923.1 - 3.8e-08 32.9 7.9 0.068 12.5 0.0 6.5 3 2 4 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 GAM34923.1 - 5.8e-05 23.1 31.6 0.31 11.2 2.1 6.8 6 0 0 6 6 6 3 FG-GAP repeat Lipase_GDSL_3 PF14606.6 GAM34923.1 - 0.13 12.3 0.0 0.35 11.0 0.0 1.7 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Dockerin_1 PF00404.18 GAM34923.1 - 1.8 8.8 20.1 16 5.8 0.2 6.5 7 0 0 7 7 7 0 Dockerin type I domain EF-hand_1 PF00036.32 GAM34923.1 - 4.9 6.9 17.6 8.9 6.1 0.1 5.4 6 0 0 6 6 6 0 EF hand MFS_1 PF07690.16 GAM34924.1 - 8.5e-26 90.7 32.3 1.3e-23 83.5 12.4 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAM34924.1 - 0.0017 16.8 14.3 0.02 13.2 0.5 3.3 1 1 2 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family DAO PF01266.24 GAM34925.1 - 1.4e-24 87.4 0.0 1.9e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM34925.1 - 9.4e-05 21.8 0.0 0.045 13.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM34925.1 - 0.0002 20.7 0.0 0.00047 19.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 GAM34925.1 - 0.0047 17.1 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAM34925.1 - 0.0098 15.0 0.1 0.15 11.1 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAM34925.1 - 0.019 14.0 0.6 0.097 11.7 0.6 2.1 1 1 0 1 1 1 0 FAD binding domain Vps5 PF09325.10 GAM34927.1 - 1.6e-14 54.1 0.3 2.6e-14 53.4 0.3 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 GAM34927.1 - 7.7e-08 32.3 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 PX domain GTP_EFTU PF00009.27 GAM34928.1 - 1.8e-55 187.5 0.0 3.4e-55 186.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 GAM34928.1 - 3.4e-27 94.3 0.0 9.9e-27 92.9 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 GAM34928.1 - 1.8e-15 56.7 0.1 2.8e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus RF3_C PF16658.5 GAM34928.1 - 5e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 GAM34928.1 - 9.3e-05 22.8 0.0 0.00032 21.0 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 GAM34928.1 - 0.0013 18.5 0.1 0.031 14.0 0.0 2.7 2 0 0 2 2 2 1 Elongation factor G, domain IV ArfGap PF01412.18 GAM34929.1 - 2.1e-20 72.9 0.0 4.3e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.22 GAM34930.1 - 8e-32 108.9 0.2 7.1e-15 54.6 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM34930.1 - 5.5e-06 26.0 0.0 0.06 12.9 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM34930.1 - 0.00017 21.6 0.0 0.045 13.9 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 GAM34930.1 - 0.001 19.4 0.3 3.2 8.0 0.0 3.1 2 2 1 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter DbpA PF03880.15 GAM34930.1 - 0.019 15.0 0.1 9.3 6.3 0.0 2.5 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_Rrp7 PF17799.1 GAM34930.1 - 0.1 12.4 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain FXMRP1_C_core PF12235.8 GAM34930.1 - 0.11 13.1 8.2 0.27 11.9 8.2 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal DUF2985 PF11204.8 GAM34931.1 - 1.2e-22 79.8 4.1 2.1e-22 79.1 4.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Pneumo_att_G PF05539.11 GAM34931.1 - 0.5 9.9 6.5 0.78 9.3 6.5 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DHR10 PF18595.1 GAM34932.1 - 0.0029 17.6 5.1 0.0029 17.6 5.1 2.9 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain DUF4047 PF13256.6 GAM34932.1 - 0.093 12.9 1.6 0.47 10.7 0.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) GAS PF13851.6 GAM34932.1 - 0.26 10.6 10.5 0.58 9.5 1.5 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 GAM34932.1 - 0.27 11.4 2.4 0.55 10.4 2.4 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family YabA PF06156.13 GAM34932.1 - 0.34 11.6 7.9 0.49 11.1 0.9 2.6 2 0 0 2 2 2 0 Initiation control protein YabA FapA PF03961.13 GAM34932.1 - 0.38 9.3 2.7 0.61 8.6 2.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Syntaxin-6_N PF09177.11 GAM34932.1 - 1.2 9.8 6.3 1.1 9.8 0.8 3.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Lebercilin PF15619.6 GAM34932.1 - 1.4 8.5 13.4 1.9 8.1 3.3 2.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CENP-H PF05837.12 GAM34932.1 - 9 6.8 11.4 5.5 7.4 1.5 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) VASt PF16016.5 GAM34933.1 - 1.3e-33 116.5 0.0 3.1e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 GAM34933.1 - 6.3e-22 77.6 0.0 1.1e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Glyco_hydro_3 PF00933.21 GAM34934.1 - 6.8e-59 199.8 0.0 9.7e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 GAM34934.1 - 8.8e-54 182.6 0.0 1.6e-53 181.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 GAM34934.1 - 5.5e-22 77.7 3.3 3.6e-21 75.0 0.5 2.5 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.13 GAM34934.1 - 0.0087 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Putative sugar-binding domain Glyco_hydro_12 PF01670.16 GAM34935.1 - 2.8e-42 145.1 9.5 3.2e-42 144.9 9.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Phage_holin_5_1 PF06946.11 GAM34935.1 - 0.076 13.4 0.5 0.16 12.3 0.5 1.5 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 Mg_trans_NIPA PF05653.14 GAM34936.1 - 1.4e-57 195.0 7.9 1.4e-57 195.0 7.9 1.7 2 0 0 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 GAM34936.1 - 0.00011 22.4 2.1 0.00011 22.4 2.1 2.5 2 0 0 2 2 2 1 EamA-like transporter family DUF3040 PF11239.8 GAM34936.1 - 0.24 11.7 1.0 24 5.3 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) WD40 PF00400.32 GAM34937.1 - 1.2e-16 60.7 12.6 0.0029 18.4 0.4 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM34937.1 - 2.3e-06 27.8 0.0 0.19 12.1 0.1 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain VID27_N PF17748.1 GAM34937.1 - 0.018 14.9 0.7 0.041 13.7 0.7 1.6 1 0 0 1 1 1 0 VID27 N-terminal region eIF2A PF08662.11 GAM34937.1 - 0.077 12.9 0.2 1.1 9.1 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A CENP-B_dimeris PF09026.10 GAM34937.1 - 0.25 11.8 13.2 0.51 10.8 13.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 GAM34937.1 - 2.2 7.9 16.7 0.11 12.3 9.8 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GAM34937.1 - 2.6 7.3 10.5 4.1 6.6 10.5 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GAM34937.1 - 8.7 4.3 10.5 12 3.8 10.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cyclin_C_2 PF16899.5 GAM34938.1 - 1.2e-37 128.4 0.1 5.2e-34 116.8 0.0 2.5 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 GAM34938.1 - 5.8e-06 26.1 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain UQ_con PF00179.26 GAM34939.1 - 3.6e-43 146.6 0.0 4.5e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 GAM34939.1 - 2.8e-05 23.8 0.0 5.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain RWD PF05773.22 GAM34939.1 - 0.037 14.3 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 RWD domain DUF2095 PF09868.9 GAM34939.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) AAA PF00004.29 GAM34940.1 - 7.9e-41 139.6 0.0 1.9e-40 138.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM34940.1 - 2.1e-11 43.4 0.3 4.8e-11 42.3 0.3 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 GAM34940.1 - 1.3e-09 37.8 0.1 2.7e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 GAM34940.1 - 7.8e-06 26.1 0.0 1.9e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAM34940.1 - 8.8e-06 25.8 0.0 2.5e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAM34940.1 - 1.6e-05 25.2 0.2 0.029 14.6 0.1 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 GAM34940.1 - 1.9e-05 24.0 0.0 3.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 GAM34940.1 - 0.0005 20.5 0.2 0.01 16.2 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAM34940.1 - 0.00058 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 GAM34940.1 - 0.0097 15.8 0.0 0.052 13.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAM34940.1 - 0.0098 16.1 0.2 0.038 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAM34940.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 GAM34940.1 - 0.016 14.4 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 GAM34940.1 - 0.017 15.3 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAM34940.1 - 0.024 15.2 0.0 0.092 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 GAM34940.1 - 0.029 13.8 0.3 0.29 10.5 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 GAM34940.1 - 0.03 13.6 0.1 0.37 10.1 0.1 2.2 1 1 0 2 2 2 0 KaiC NACHT PF05729.12 GAM34940.1 - 0.035 14.0 0.1 0.82 9.6 0.1 2.6 2 1 1 3 3 3 0 NACHT domain Zeta_toxin PF06414.12 GAM34940.1 - 0.037 13.3 0.1 0.097 11.9 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 GAM34940.1 - 0.044 13.2 0.1 0.097 12.0 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GAM34940.1 - 0.062 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 GAM34940.1 - 0.086 12.8 0.5 0.7 9.8 0.0 2.5 3 0 0 3 3 3 0 NTPase AAA_14 PF13173.6 GAM34940.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAM34940.1 - 0.13 12.0 1.2 0.26 11.0 0.3 2.1 2 1 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 GAM34940.1 - 0.16 11.7 0.7 0.7 9.6 0.0 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_7 PF12775.7 GAM34940.1 - 0.17 11.4 0.1 0.39 10.2 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 GAM34940.1 - 2.3 7.7 6.3 1.4 8.4 0.3 3.0 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 GAM34941.1 - 3.2e-38 131.3 0.0 5e-21 75.7 0.0 3.9 3 1 1 4 4 4 3 ABC transporter ABC_tran_Xtn PF12848.7 GAM34941.1 - 5.7e-21 74.4 1.7 5.7e-21 74.4 1.7 3.4 5 0 0 5 5 2 1 ABC transporter AAA_21 PF13304.6 GAM34941.1 - 3.6e-16 59.9 1.6 0.0014 18.5 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM34941.1 - 4.1e-10 39.5 0.5 0.46 9.9 0.0 4.4 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM34941.1 - 8.1e-08 31.9 0.1 0.015 15.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAM34941.1 - 1.2e-07 32.4 0.6 0.013 16.1 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 GAM34941.1 - 4.3e-06 26.7 0.0 0.049 13.3 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 GAM34941.1 - 6.9e-05 23.2 0.4 0.3 11.5 0.0 3.2 3 0 0 3 3 3 2 RNA helicase AAA_18 PF13238.6 GAM34941.1 - 0.00015 22.3 0.1 0.63 10.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 GAM34941.1 - 0.00019 21.9 0.0 0.51 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_27 PF13514.6 GAM34941.1 - 0.00021 20.9 0.0 0.011 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAM34941.1 - 0.00023 21.1 0.0 0.67 9.8 0.0 2.7 3 0 0 3 3 3 2 RsgA GTPase AAA_24 PF13479.6 GAM34941.1 - 0.0003 20.6 0.1 0.49 10.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 GAM34941.1 - 0.00092 19.5 0.0 0.057 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 GAM34941.1 - 0.0015 18.6 0.0 1.9 8.6 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA PF00004.29 GAM34941.1 - 0.0017 18.8 0.0 4.2 7.8 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GAM34941.1 - 0.0017 17.9 0.1 0.051 13.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAM34941.1 - 0.0056 17.0 0.0 4 7.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAM34941.1 - 0.0073 16.2 0.1 0.75 9.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 GAM34941.1 - 0.0082 16.3 0.5 2.2 8.4 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.14 GAM34941.1 - 0.0094 16.0 0.0 3.7 7.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 GAM34941.1 - 0.012 14.9 0.0 12 5.0 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain Roc PF08477.13 GAM34941.1 - 0.03 14.5 0.0 15 5.8 0.0 2.9 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GST_C_3 PF14497.6 GAM34941.1 - 0.044 14.0 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_7 PF12775.7 GAM34941.1 - 0.051 13.1 0.1 3.5 7.1 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region PduV-EutP PF10662.9 GAM34941.1 - 0.11 12.3 0.1 6.7 6.5 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation HPP PF04982.13 GAM34942.1 - 1.8e-39 134.7 9.7 1.8e-39 134.7 9.7 1.6 2 0 0 2 2 2 1 HPP family FeoB_C PF07664.12 GAM34942.1 - 0.13 11.9 2.7 3.5 7.4 0.2 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus GFO_IDH_MocA PF01408.22 GAM34943.1 - 2.3e-22 80.1 0.0 4.3e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAM34943.1 - 3.5e-11 43.1 0.0 8.4e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 GAM34943.1 - 0.0006 20.5 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.19 GAM34943.1 - 0.0015 19.2 0.0 0.0034 18.0 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain DapB_N PF01113.20 GAM34943.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CoA_binding_2 PF13380.6 GAM34943.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain OCD_Mu_crystall PF02423.15 GAM34943.1 - 0.094 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Sacchrp_dh_NADP PF03435.18 GAM34943.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF4350 PF14258.6 GAM34943.1 - 0.16 12.4 0.0 2.2 8.8 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4350) MARVEL PF01284.23 GAM34945.1 - 1.8e-10 41.0 6.5 2.7e-10 40.4 6.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain CbtA PF09490.10 GAM34945.1 - 0.0083 15.9 0.9 0.41 10.4 0.5 2.3 1 1 1 2 2 2 1 Probable cobalt transporter subunit (CbtA) DUF898 PF05987.13 GAM34945.1 - 0.016 14.3 1.1 0.021 13.9 0.2 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Peptidase_M56 PF05569.11 GAM34945.1 - 0.096 11.9 0.1 0.21 10.7 0.1 1.6 1 1 0 1 1 1 0 BlaR1 peptidase M56 TMEM223 PF14640.6 GAM34945.1 - 0.13 12.5 0.2 0.2 11.8 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 223 TPR_2 PF07719.17 GAM34946.1 - 6.3e-07 29.0 3.3 0.028 14.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM34946.1 - 3.2e-05 23.5 0.7 2 8.4 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM34946.1 - 6.6e-05 23.5 1.2 0.45 11.2 0.2 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM34946.1 - 0.00012 21.9 0.2 1.1 9.4 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM34946.1 - 0.00046 20.4 0.9 0.15 12.4 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM34946.1 - 0.0023 18.4 0.3 0.22 12.1 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM34946.1 - 0.016 15.4 1.5 2.7 8.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM34946.1 - 0.061 13.0 2.5 15 5.4 0.2 3.1 3 0 0 3 3 3 0 TPR repeat TPR_4 PF07721.14 GAM34946.1 - 0.082 13.6 0.5 0.26 12.0 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM34946.1 - 0.088 12.7 2.7 0.21 11.5 0.0 2.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM34946.1 - 0.18 12.7 1.7 1.5 9.8 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Cu_amine_oxid PF01179.20 GAM34947.1 - 6.6e-161 535.8 0.0 7.9e-161 535.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 GAM34947.1 - 3.7e-22 78.6 0.2 1.5e-21 76.7 0.1 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 GAM34947.1 - 1.4e-09 38.1 0.0 2.5e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Sugar_tr PF00083.24 GAM34948.1 - 6.8e-84 282.3 20.0 7.9e-84 282.1 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM34948.1 - 1.2e-30 106.6 43.5 2.5e-26 92.4 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LptF_LptG PF03739.14 GAM34948.1 - 0.015 14.1 2.2 0.032 13.1 2.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF4149 PF13664.6 GAM34948.1 - 1.8 8.9 6.9 0.27 11.6 0.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Abhydrolase_6 PF12697.7 GAM34949.1 - 1.1e-14 55.6 0.2 1.5e-14 55.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM34949.1 - 0.00015 21.5 0.0 0.067 12.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM34949.1 - 0.0026 17.0 0.0 0.02 14.2 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF900 PF05990.12 GAM34949.1 - 0.017 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Methyltransf_24 PF13578.6 GAM34949.1 - 0.07 14.2 0.6 6.4 7.8 0.1 2.9 1 1 1 3 3 3 0 Methyltransferase domain Melibiase_2 PF16499.5 GAM34950.1 - 6.3e-54 183.1 5.9 5.7e-53 179.9 5.9 2.2 1 1 0 1 1 1 1 Alpha galactosidase A Alginate_lyase PF05426.12 GAM34950.1 - 2e-12 47.2 7.5 7.5e-12 45.4 7.5 1.8 1 1 0 1 1 1 1 Alginate lyase Melibiase_C PF17801.1 GAM34950.1 - 1.1e-08 35.0 2.2 3.9e-08 33.2 0.0 3.1 4 0 0 4 4 4 1 Alpha galactosidase C-terminal beta sandwich domain Fasciclin PF02469.22 GAM34950.1 - 2e-08 34.5 0.4 4.2e-08 33.5 0.4 1.4 1 0 0 1 1 1 1 Fasciclin domain Melibiase PF02065.18 GAM34950.1 - 2.4e-06 26.7 0.0 5.7e-06 25.5 0.0 1.5 2 0 0 2 2 2 1 Melibiase Glyco_hydro_43 PF04616.14 GAM34951.1 - 2.8e-64 217.2 0.3 3.7e-64 216.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 GAM34951.1 - 2.8e-28 99.0 0.0 4.3e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Alginate_lyase PF05426.12 GAM34952.1 - 4.5e-06 26.4 8.8 1.1e-05 25.2 8.5 1.6 1 1 0 1 1 1 1 Alginate lyase adh_short PF00106.25 GAM34953.1 - 3e-31 108.4 0.0 1.2e-30 106.4 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM34953.1 - 1.2e-20 74.1 0.0 4.3e-19 69.0 0.0 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM34953.1 - 0.0011 18.9 0.0 0.0043 17.0 0.0 1.8 2 0 0 2 2 2 1 KR domain Methyltransf_31 PF13847.6 GAM34953.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAM34953.1 - 0.068 13.9 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain A_deaminase PF00962.22 GAM34954.1 - 5.5e-46 157.4 0.0 8.1e-46 156.9 0.0 1.2 1 1 0 1 1 1 1 Adenosine/AMP deaminase Fungal_trans_2 PF11951.8 GAM34955.1 - 2.3e-32 112.3 1.5 3.9e-32 111.5 1.5 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain SNF2_N PF00176.23 GAM34956.1 - 3.7e-20 71.9 0.0 5.4e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 GAM34956.1 - 0.03 14.3 0.0 0.083 12.9 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM34956.1 - 0.094 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase zf-H2C2_2 PF13465.6 GAM34957.1 - 0.00017 21.9 0.5 0.00017 21.9 0.5 4.9 6 0 0 6 6 6 2 Zinc-finger double domain DUF676 PF05057.14 GAM34957.1 - 0.01 15.4 1.5 0.016 14.7 0.0 2.1 3 0 0 3 3 3 1 Putative serine esterase (DUF676) zf-C2H2 PF00096.26 GAM34957.1 - 0.011 16.1 6.9 0.011 16.1 6.9 6.0 5 0 0 5 5 5 0 Zinc finger, C2H2 type Bac_chlorC PF02043.17 GAM34957.1 - 0.014 15.4 0.0 0.037 14.0 0.0 1.8 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein EGF_CA PF07645.15 GAM34957.1 - 0.24 11.6 2.4 0.67 10.2 0.1 2.4 2 0 0 2 2 2 0 Calcium-binding EGF domain zf-C2HE PF16278.5 GAM34957.1 - 0.34 11.4 8.6 0.29 11.6 2.3 3.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_4 PF13894.6 GAM34957.1 - 0.47 11.4 36.7 0.068 14.0 4.7 5.9 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAM34957.1 - 0.69 10.0 18.5 3.4 7.8 5.7 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger C1_2 PF03107.16 GAM34957.1 - 2.1 8.7 7.2 3.5 8.0 1.6 2.8 1 1 1 2 2 2 0 C1 domain zf-met PF12874.7 GAM34957.1 - 2.2 8.8 15.4 1.7 9.1 3.5 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Abhydrolase_6 PF12697.7 GAM34958.1 - 1.1e-14 55.6 0.1 1.4e-14 55.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM34958.1 - 8.9e-09 35.4 0.1 1.9e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM34958.1 - 4.4e-08 32.7 0.0 7.6e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 GAM34958.1 - 0.0094 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 GAM34958.1 - 0.029 14.1 0.2 0.1 12.3 0.0 1.8 2 1 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.20 GAM34958.1 - 0.031 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.13 GAM34958.1 - 0.039 13.8 0.1 0.091 12.6 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_5 PF12695.7 GAM34958.1 - 0.047 13.5 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family CAF1 PF04857.20 GAM34959.1 - 2.8e-22 79.3 0.2 1.1e-10 41.3 0.0 2.6 3 0 0 3 3 3 2 CAF1 family ribonuclease NDUF_B12 PF08122.12 GAM34960.1 - 9.8e-26 89.6 1.3 1.3e-25 89.1 1.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family WD40 PF00400.32 GAM34961.1 - 1.1e-17 64.0 7.5 0.0017 19.1 0.0 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM34961.1 - 0.00028 21.1 0.0 0.27 11.6 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM34961.1 - 0.43 9.5 1.3 3.5 6.5 0.0 3.0 5 0 0 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AMP-binding PF00501.28 GAM34962.1 - 3.1e-52 177.6 0.1 2.4e-36 125.3 0.1 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 GAM34962.1 - 1.4e-14 54.8 0.7 3.1e-14 53.7 0.7 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy_2 PF13532.6 GAM34963.1 - 2.4e-25 89.9 0.0 4.5e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CNH PF00780.22 GAM34964.1 - 4.8e-62 210.1 0.0 7.8e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 GAM34964.1 - 4.5e-33 115.0 0.8 7.5e-33 114.3 0.8 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 GAM34964.1 - 5.4e-13 49.2 0.0 2e-12 47.4 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 GAM34964.1 - 0.0037 17.8 0.0 0.016 15.7 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_16 PF17838.1 GAM34964.1 - 0.058 13.2 0.1 6.7 6.6 0.0 2.5 2 0 0 2 2 2 0 PH domain PH_13 PF16652.5 GAM34964.1 - 0.11 12.3 0.6 0.56 10.0 0.0 2.4 3 0 0 3 3 3 0 Pleckstrin homology domain Ank_2 PF12796.7 GAM34965.1 - 3.2e-10 40.5 0.5 0.00019 22.0 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM34965.1 - 4.6e-10 39.8 0.8 0.027 15.1 0.2 4.8 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM34965.1 - 0.00019 21.6 4.9 0.013 15.8 0.5 4.4 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 GAM34965.1 - 0.00023 21.5 1.8 0.084 13.4 0.2 4.6 5 1 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.6 GAM34965.1 - 0.0029 18.0 1.6 1.5 9.6 0.1 4.9 4 1 1 5 5 5 1 Ankyrin repeat adh_short PF00106.25 GAM34966.1 - 5e-21 75.0 3.3 2.4e-20 72.8 3.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM34966.1 - 2.3e-15 56.8 3.0 8e-14 51.8 3.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM34966.1 - 4.9e-07 29.8 1.0 6e-07 29.5 0.2 1.5 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GAM34966.1 - 0.0075 15.4 0.1 0.0098 15.1 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein His_biosynth PF00977.21 GAM34966.1 - 0.044 13.2 1.0 0.35 10.3 0.7 1.9 1 1 1 2 2 2 0 Histidine biosynthesis protein Sacchrp_dh_NADP PF03435.18 GAM34966.1 - 0.052 13.8 0.3 0.087 13.1 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 GAM34967.1 - 9.5e-10 38.4 0.0 1.2e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RabGAP-TBC PF00566.18 GAM34969.1 - 7.1e-47 159.8 0.0 1.1e-46 159.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 GAM34969.1 - 0.00018 21.3 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 GAM34969.1 - 0.00064 19.5 0.3 0.0044 16.8 0.3 2.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 GAM34969.1 - 0.046 13.3 1.0 0.22 11.2 1.0 2.3 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 GAM34969.1 - 0.076 12.5 0.7 0.34 10.5 0.7 2.2 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 GAM34969.1 - 0.29 11.6 2.3 0.6 10.6 0.1 2.8 3 0 0 3 3 3 0 EF-hand domain pair PNP_UDP_1 PF01048.20 GAM34970.1 - 7.8e-17 61.3 0.0 1.5e-16 60.3 0.0 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily NUP PF06516.11 GAM34970.1 - 0.042 13.1 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Purine nucleoside permease (NUP) XPC-binding PF09280.11 GAM34970.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 XPC-binding domain Exo_endo_phos PF03372.23 GAM34971.1 - 0.00086 18.9 0.1 0.0019 17.8 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3712 PF12505.8 GAM34976.1 - 4.3e-27 94.9 0.1 1.9e-25 89.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Metallophos PF00149.28 GAM34976.1 - 2.9e-14 54.0 0.1 6.5e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 GAM34976.1 - 1.9e-13 50.8 3.0 4.4e-13 49.6 3.0 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 GAM34976.1 - 2.4e-12 47.5 0.0 6.3e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD_N PF16655.5 GAM34976.1 - 0.00069 20.1 0.1 0.0014 19.1 0.1 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain ADD_DNMT3 PF17980.1 GAM34976.1 - 0.082 12.9 1.1 3.9 7.6 0.1 2.4 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 Asp PF00026.23 GAM34977.1 - 2.4e-53 181.6 0.0 3e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM34977.1 - 0.00012 22.4 0.0 0.67 10.2 0.0 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAM34977.1 - 0.0047 17.5 0.4 0.13 12.9 0.3 2.8 2 1 0 2 2 2 1 Aspartyl protease Peptidase_S10 PF00450.22 GAM34978.1 - 8.2e-95 318.7 0.0 1.1e-94 318.2 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Amidohydro_2 PF04909.14 GAM34980.1 - 0.00052 19.9 0.1 0.0022 17.8 0.0 1.8 1 1 0 2 2 2 1 Amidohydrolase K_oxygenase PF13434.6 GAM34982.1 - 1.3e-11 44.3 0.4 1.4e-07 31.0 0.0 3.6 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 GAM34982.1 - 1.5e-07 30.9 0.0 0.00063 19.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM34982.1 - 2.1e-07 31.1 0.0 5.4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 GAM34982.1 - 1.4e-06 27.1 0.0 5.6e-06 25.1 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAM34982.1 - 6.5e-06 25.6 0.0 0.00082 18.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM34982.1 - 0.016 15.2 0.2 0.47 10.4 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 GAM34982.1 - 0.025 14.7 0.0 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FA_hydroxylase PF04116.13 GAM34983.1 - 4e-22 79.0 14.0 4e-22 79.0 14.0 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily RTC PF01137.21 GAM34984.1 - 7.6e-49 165.9 0.0 1.2e-48 165.2 0.0 1.3 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase DUF1772 PF08592.11 GAM34985.1 - 0.00015 22.1 2.6 0.00054 20.3 2.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) BAR PF03114.18 GAM34988.1 - 2.4e-15 56.8 1.9 3.3e-15 56.4 1.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 GAM34988.1 - 3e-12 46.2 0.2 5.3e-12 45.4 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM34988.1 - 5.1e-12 45.2 0.1 8.7e-12 44.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAM34988.1 - 2.9e-09 36.5 0.2 3.5e-08 33.0 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain Apolipoprotein PF01442.18 GAM34988.1 - 0.021 14.7 1.4 0.037 13.9 1.4 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain GAS PF13851.6 GAM34988.1 - 0.56 9.5 7.2 1.2 8.4 7.2 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CCDC-167 PF15188.6 GAM34988.1 - 1.4 9.3 3.5 0.62 10.4 1.1 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Mac PF12464.8 GAM34989.1 - 2.3e-14 53.3 0.0 4.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 GAM34989.1 - 2.9e-12 45.8 15.8 5.2e-11 41.8 4.3 3.4 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAM34989.1 - 1.4e-08 34.4 10.1 1.5e-07 31.1 2.5 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF2439 PF10382.9 GAM34990.1 - 2.4e-29 101.5 0.3 4e-29 100.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Gln-synt_C PF00120.24 GAM34991.1 - 2.5e-51 174.7 0.0 3.4e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 GAM34991.1 - 0.00021 21.1 0.0 0.00063 19.5 0.0 1.7 2 0 0 2 2 2 1 Glutamine synthetase N-terminal domain Amidase PF01425.21 GAM34992.1 - 6.9e-50 170.3 0.3 7.7e-47 160.3 0.2 2.2 2 0 0 2 2 2 2 Amidase Amidase PF01425.21 GAM34993.1 - 1.2e-84 284.9 0.0 3.8e-84 283.3 0.0 1.7 1 1 0 1 1 1 1 Amidase TPR_12 PF13424.6 GAM34994.1 - 5.1e-27 94.0 8.5 2.1e-14 53.6 0.4 3.9 3 1 1 4 4 4 4 Tetratricopeptide repeat NB-ARC PF00931.22 GAM34994.1 - 1.7e-14 53.6 0.0 3.1e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.28 GAM34994.1 - 5.6e-12 44.9 8.6 0.00062 19.5 0.0 5.7 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM34994.1 - 2.6e-10 39.6 8.1 0.16 12.2 0.0 6.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAM34994.1 - 1.5e-09 37.4 6.4 0.00019 21.2 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM34994.1 - 3.1e-09 36.2 1.6 0.13 12.4 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM34994.1 - 1.3e-06 28.1 9.9 0.21 11.9 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM34994.1 - 1.7e-06 27.6 1.6 0.00037 20.0 0.8 2.7 1 1 2 3 3 3 3 MalT-like TPR region SNAP PF14938.6 GAM34994.1 - 2.9e-06 26.9 0.8 5.7e-05 22.7 0.8 2.3 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP PNP_UDP_1 PF01048.20 GAM34994.1 - 3.5e-06 26.4 0.4 1.2e-05 24.7 0.4 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.6 GAM34994.1 - 1.3e-05 25.7 0.0 0.0001 22.7 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain TPR_11 PF13414.6 GAM34994.1 - 1.5e-05 24.6 0.7 0.17 11.6 0.0 4.9 6 0 0 6 6 6 1 TPR repeat TPR_19 PF14559.6 GAM34994.1 - 0.00028 21.3 1.4 3 8.4 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.6 GAM34994.1 - 0.00056 20.2 0.0 0.0021 18.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain SPO22 PF08631.10 GAM34994.1 - 0.0016 18.0 1.8 0.11 11.9 0.4 2.4 1 1 1 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_16 PF13432.6 GAM34994.1 - 0.0023 18.6 1.0 9.5 7.0 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TniB PF05621.11 GAM34994.1 - 0.0029 17.0 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein TPR_21 PF09976.9 GAM34994.1 - 0.011 15.4 0.6 4.7 6.9 0.0 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 GAM34994.1 - 0.013 15.6 1.0 7.4 6.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAM34994.1 - 0.014 14.8 0.0 0.47 9.9 0.0 2.7 2 0 0 2 2 2 0 SHNi-TPR TPR_6 PF13174.6 GAM34994.1 - 0.026 15.2 1.6 18 6.2 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM34994.1 - 0.88 9.8 3.0 32 4.9 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 GAM34994.1 - 0.88 9.7 3.3 11 6.2 0.1 3.0 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Methyltransf_23 PF13489.6 GAM34995.1 - 1.1e-16 61.1 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM34995.1 - 2.5e-07 31.4 0.0 7e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM34995.1 - 7.8e-07 29.7 0.0 2e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM34995.1 - 3.3e-05 23.7 0.0 0.00018 21.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM34995.1 - 9.7e-05 23.0 0.0 0.00073 20.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM34995.1 - 0.0044 16.4 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 GAM34995.1 - 0.07 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Mcp5_PH PF12814.7 GAM34996.1 - 5.1e-45 152.5 0.5 1.2e-44 151.4 0.1 1.9 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 GAM34996.1 - 0.00055 20.4 0.0 0.0014 19.1 0.0 1.8 1 0 0 1 1 1 1 PH domain SHE3 PF17078.5 GAM34996.1 - 3.3 7.4 19.1 0.09 12.5 8.4 2.9 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 Selenoprotein_S PF06936.11 GAM34996.1 - 4.4 7.1 10.7 0.7 9.7 4.4 2.5 2 0 0 2 2 2 0 Selenoprotein S (SelS) zf-CCCH PF00642.24 GAM34997.1 - 1.1e-09 38.0 2.6 2.2e-09 37.0 2.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 GAM34997.1 - 8.8e-09 35.1 8.0 1.8e-08 34.1 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM34997.1 - 2.1e-08 34.0 6.2 4.4e-08 33.0 6.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAM34997.1 - 2.8e-08 33.5 6.7 5.7e-08 32.5 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM34997.1 - 7.3e-07 29.0 10.7 1.4e-06 28.1 10.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM34997.1 - 4.8e-06 26.4 9.0 8.6e-06 25.6 9.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 GAM34997.1 - 1.3e-05 25.1 7.0 2.6e-05 24.1 7.0 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 GAM34997.1 - 1.5e-05 25.1 3.4 1.5e-05 25.1 3.4 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 GAM34997.1 - 2.7e-05 24.4 7.3 2.7e-05 24.4 7.3 1.6 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 GAM34997.1 - 0.00024 20.9 6.7 0.00045 20.0 6.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAM34997.1 - 0.0015 18.7 8.9 0.0033 17.6 8.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH_4 PF18044.1 GAM34997.1 - 0.0043 16.8 3.0 0.0043 16.8 3.0 2.1 2 0 0 2 2 1 1 CCCH-type zinc finger zf-rbx1 PF12678.7 GAM34997.1 - 0.13 12.6 4.3 0.28 11.5 4.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 GAM34997.1 - 0.2 11.5 2.5 0.36 10.7 2.5 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-CCCH_2 PF14608.6 GAM34997.1 - 3.7 8.2 9.9 0.19 12.3 4.4 1.8 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger Ku PF02735.16 GAM34998.1 - 3.3e-42 144.5 0.0 8.2e-42 143.2 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 GAM34998.1 - 2.3e-33 115.8 0.0 4.3e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 GAM34998.1 - 1.4e-27 96.2 5.5 1.4e-27 96.2 5.5 2.3 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 GAM34998.1 - 1.3e-11 44.0 0.2 2.3e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 GAM34998.1 - 0.015 15.0 0.6 0.044 13.5 0.6 1.9 1 0 0 1 1 1 0 HeH/LEM domain VWA_2 PF13519.6 GAM34998.1 - 0.16 12.7 0.0 0.93 10.2 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Ferrochelatase PF00762.19 GAM34999.1 - 5.8e-98 327.9 0.0 7.4e-98 327.5 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase MFS_1 PF07690.16 GAM34999.1 - 2.1e-13 50.0 25.5 9.6e-10 37.9 7.6 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily PPR_2 PF13041.6 GAM35000.1 - 0.00018 21.6 0.0 0.039 14.2 0.0 3.5 4 0 0 4 4 4 1 PPR repeat family TPR_19 PF14559.6 GAM35000.1 - 0.0013 19.2 0.5 45 4.7 0.0 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM35000.1 - 0.0074 16.1 0.9 2 8.4 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.20 GAM35000.1 - 0.1 12.9 0.0 6.1 7.3 0.0 3.9 4 0 0 4 4 4 0 PPR repeat PBECR5 PF18814.1 GAM35000.1 - 0.1 12.5 0.5 0.2 11.6 0.5 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 SE PF08491.10 GAM35001.1 - 3.7e-97 324.7 0.0 4.6e-97 324.4 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 GAM35001.1 - 7e-14 51.8 0.0 2.1e-13 50.3 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM35001.1 - 4.9e-09 36.2 0.3 4.1e-06 26.6 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 GAM35001.1 - 2.6e-06 26.8 0.2 0.00029 20.1 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GAM35001.1 - 8.8e-06 25.0 0.4 0.00049 19.3 0.3 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAM35001.1 - 2.3e-05 23.7 2.5 4.2e-05 22.8 1.2 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GAM35001.1 - 2.5e-05 24.4 0.8 5.2e-05 23.4 0.8 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM35001.1 - 7.9e-05 22.0 0.1 0.00014 21.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM35001.1 - 0.00022 20.5 0.0 0.00075 18.8 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 GAM35001.1 - 0.00058 19.3 0.2 0.00094 18.6 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM35001.1 - 0.00059 20.3 0.1 0.0014 19.2 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM35001.1 - 0.0011 17.8 0.1 0.0015 17.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.16 GAM35001.1 - 0.0026 17.4 0.2 0.0047 16.6 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 GAM35001.1 - 0.0028 17.7 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 GAM35001.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAM35001.1 - 0.044 13.1 0.0 0.092 12.0 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 GAM35001.1 - 0.047 12.5 0.3 0.19 10.5 0.3 1.9 2 0 0 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.23 GAM35001.1 - 0.067 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PAP_assoc PF03828.19 GAM35002.1 - 1.9e-18 66.4 0.1 4.4e-18 65.2 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF908 PF06012.12 GAM35002.1 - 5.6 6.3 15.1 3.1 7.1 7.9 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) SLC35F PF06027.12 GAM35004.1 - 3.8e-89 299.1 21.1 4.5e-89 298.9 21.1 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 GAM35004.1 - 2.4e-08 33.3 4.3 4.5e-08 32.4 4.3 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 GAM35004.1 - 4.3e-06 26.9 34.4 0.0033 17.6 13.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family HCV_env PF01539.17 GAM35004.1 - 0.028 14.1 1.1 0.057 13.1 1.1 1.4 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 SMK-1 PF04802.15 GAM35005.1 - 9.4e-81 270.2 1.3 9.4e-81 270.2 1.3 1.7 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 DCP1 PF06058.13 GAM35006.1 - 4.8e-29 100.7 0.0 4.8e-29 100.7 0.0 1.6 2 0 0 2 2 2 1 Dcp1-like decapping family Exo_endo_phos PF03372.23 GAM35007.1 - 1.9e-05 24.3 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FAM176 PF14851.6 GAM35008.1 - 0.0025 17.5 0.2 0.26 11.0 0.1 2.4 2 0 0 2 2 2 2 FAM176 family HSBP1 PF06825.12 GAM35008.1 - 0.03 14.2 0.2 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Abhydrolase_6 PF12697.7 GAM35009.1 - 1e-09 39.4 0.0 1.3e-09 39.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 GAM35009.1 - 3.7e-09 35.7 0.1 6.1e-05 21.8 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 GAM35009.1 - 1.2e-08 34.5 0.1 1.6e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 GAM35009.1 - 2.6e-08 33.8 0.0 3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 GAM35009.1 - 1.7e-06 27.8 0.0 2.3e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 GAM35009.1 - 9.6e-05 22.4 0.0 0.00033 20.6 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 GAM35009.1 - 0.001 18.6 0.1 0.023 14.2 0.0 2.2 1 1 0 2 2 2 1 Prolyl oligopeptidase family F-box-like PF12937.7 GAM35011.1 - 0.00021 21.1 0.0 0.0006 19.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like Abhydrolase_6 PF12697.7 GAM35012.1 - 4.4e-10 40.6 0.3 1.5e-09 38.8 0.3 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.11 GAM35012.1 - 3.6e-07 29.3 0.0 5.3e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Hydrolase_4 PF12146.8 GAM35012.1 - 2.5e-05 23.7 0.1 0.00044 19.6 0.1 2.3 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM35012.1 - 0.0001 22.1 0.1 0.00049 19.8 0.2 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM35012.1 - 0.00017 21.1 0.5 0.0003 20.3 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 GAM35012.1 - 0.0038 17.1 0.2 1.1 9.1 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAM35012.1 - 0.035 13.9 0.0 0.087 12.6 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase ANAPC8 PF04049.13 GAM35012.1 - 0.077 13.1 0.2 0.13 12.4 0.2 1.2 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 DUF4203 PF13886.6 GAM35014.1 - 3.3e-53 180.3 25.1 4.4e-53 180.0 25.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) SSB PF00436.25 GAM35015.1 - 1.7e-17 63.4 0.0 2.2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.15 GAM35016.1 - 1.8e-89 299.8 11.4 2.1e-89 299.6 11.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor S1 PF00575.23 GAM35017.1 - 1.9e-69 229.9 24.1 2.7e-13 50.0 0.7 12.2 12 1 0 12 12 12 10 S1 RNA binding domain TPR_19 PF14559.6 GAM35017.1 - 4.6e-08 33.4 0.1 0.045 14.3 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat PCB_OB PF17092.5 GAM35017.1 - 8.8e-07 29.7 3.9 2.9 8.7 0.0 7.4 6 1 1 7 7 7 1 Penicillin-binding protein OB-like domain RNase_II_C_S1 PF18614.1 GAM35017.1 - 0.00084 19.2 0.3 0.33 10.9 0.0 4.5 3 0 0 3 3 3 1 RNase II-type exonuclease C-terminal S1 domain S1_2 PF13509.6 GAM35017.1 - 0.0015 18.6 0.1 3.2 7.9 0.0 4.3 4 0 0 4 4 4 1 S1 domain TPR_16 PF13432.6 GAM35017.1 - 0.0027 18.3 1.7 15 6.4 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR PF01535.20 GAM35017.1 - 0.0035 17.5 0.0 1.8 9.0 0.0 3.3 2 0 0 2 2 2 1 PPR repeat TPR_14 PF13428.6 GAM35017.1 - 0.0038 17.9 1.7 17 6.6 0.2 5.5 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM35017.1 - 0.073 13.3 0.0 5.3 7.5 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_2 PF13041.6 GAM35017.1 - 0.14 12.4 0.0 7.2 6.9 0.0 3.0 3 0 0 3 3 3 0 PPR repeat family TPR_2 PF07719.17 GAM35017.1 - 0.28 11.4 2.6 8.5 6.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat UreD PF01774.17 GAM35019.1 - 7.3e-58 196.0 0.0 3.7e-57 193.7 0.0 1.6 1 1 1 2 2 2 2 UreD urease accessory protein STAG PF08514.11 GAM35020.1 - 5.4e-34 116.5 0.4 2.7e-33 114.3 0.1 2.4 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.6 GAM35020.1 - 0.00046 20.5 0.0 0.17 12.3 0.0 3.5 1 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 GAM35020.1 - 0.00085 19.4 0.1 7.3 7.2 0.1 4.4 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.7 GAM35020.1 - 0.0062 16.6 0.2 0.17 12.0 0.0 3.1 2 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF3887 PF13026.6 GAM35020.1 - 0.07 14.0 1.6 0.17 12.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) Nipped-B_C PF12830.7 GAM35020.1 - 0.099 12.6 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus PsaA_PsaB PF00223.19 GAM35020.1 - 0.2 9.8 0.0 0.34 9.0 0.0 1.3 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Fzo_mitofusin PF04799.13 GAM35020.1 - 0.25 10.9 4.5 7.6 6.1 0.3 3.3 3 1 0 3 3 3 0 fzo-like conserved region Arm PF00514.23 GAM35021.1 - 2.3e-97 316.4 13.1 3.7e-14 52.2 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 GAM35021.1 - 6.4e-27 93.8 1.6 1.7e-26 92.5 1.6 1.8 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 GAM35021.1 - 1e-23 82.6 3.6 2.1e-23 81.6 3.6 1.5 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 GAM35021.1 - 2.5e-22 79.1 0.4 4.3e-09 36.6 0.0 5.4 1 1 4 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 GAM35021.1 - 6.8e-22 77.6 5.8 1.5e-09 38.2 0.1 6.1 4 1 2 6 6 6 4 HEAT-like repeat HEAT PF02985.22 GAM35021.1 - 2.2e-19 67.9 0.3 3.5e-06 26.8 0.0 6.9 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.13 GAM35021.1 - 9.6e-10 38.3 0.0 0.00057 19.4 0.0 4.0 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 GAM35021.1 - 1.2e-05 25.4 0.0 0.78 9.9 0.0 4.3 3 2 1 4 4 4 2 V-ATPase subunit H Adaptin_N PF01602.20 GAM35021.1 - 1.7e-05 23.6 0.0 0.0014 17.3 0.0 2.3 1 1 1 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 GAM35021.1 - 0.00029 20.9 0.0 0.52 10.3 0.0 2.9 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 GAM35021.1 - 0.0083 16.3 2.9 1.1 9.6 0.0 4.4 4 2 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 GAM35021.1 - 0.015 15.9 5.2 0.78 10.6 0.1 4.5 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Mo25 PF08569.11 GAM35021.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Mo25-like NUSAP PF16006.5 GAM35021.1 - 3.2 7.4 6.6 4.8 6.9 6.6 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein POT1PC PF16686.5 GAM35022.1 - 1.1e-41 142.3 0.9 1.1e-41 142.3 0.9 2.4 3 0 0 3 3 3 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 GAM35022.1 - 1.5e-23 83.2 0.0 2.8e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 SOBP PF15279.6 GAM35022.1 - 0.44 11.1 7.4 0.096 13.3 3.1 1.8 2 0 0 2 2 2 0 Sine oculis-binding protein Spt20 PF12090.8 GAM35022.1 - 3.4 7.2 13.4 35 3.9 11.6 2.2 2 0 0 2 2 2 0 Spt20 family RR_TM4-6 PF06459.12 GAM35022.1 - 8.3 6.1 9.5 1.7 8.4 5.2 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4391 PF14335.6 GAM35023.1 - 0.079 12.6 1.6 0.15 11.7 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) zf-CCCH_4 PF18044.1 GAM35023.1 - 1.1 9.1 9.9 2.3 8.1 0.3 2.9 2 0 0 2 2 2 0 CCCH-type zinc finger TRAP_alpha PF03896.16 GAM35024.1 - 0.005 16.1 0.0 0.0066 15.7 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Reo_sigma1 PF01664.16 GAM35024.1 - 0.092 12.0 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Reovirus viral attachment protein sigma 1 zf-C2HE PF16278.5 GAM35025.1 - 1.3e-19 70.4 2.2 1.6e-19 70.1 0.5 2.1 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 GAM35025.1 - 8.3e-16 58.5 3.8 7.9e-15 55.3 3.8 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 GAM35025.1 - 1.3e-13 51.5 2.1 4.8e-13 49.7 2.1 1.9 1 1 0 1 1 1 1 HIT domain HA2 PF04408.23 GAM35026.1 - 5.4e-19 68.5 1.3 5.3e-18 65.3 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAM35026.1 - 9.3e-16 58.0 0.0 2.4e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAM35026.1 - 1.7e-13 50.9 0.0 4.2e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 GAM35026.1 - 3.8e-13 49.7 0.0 1.2e-12 48.1 0.0 1.9 2 0 0 2 2 1 1 RWD domain DEAD PF00270.29 GAM35026.1 - 3.1e-10 40.1 0.1 5.9e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAM35026.1 - 0.00025 21.3 1.6 0.0014 18.9 1.6 2.2 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAM35026.1 - 0.0032 16.6 0.0 0.0061 15.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 GAM35026.1 - 0.0051 16.3 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein DND1_DSRM PF14709.7 GAM35026.1 - 0.016 15.5 0.1 0.044 14.0 0.1 1.8 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 ATPase PF06745.13 GAM35026.1 - 0.027 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 KaiC dsRBD2 PF17842.1 GAM35026.1 - 0.039 14.2 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 AAA_29 PF13555.6 GAM35026.1 - 0.097 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM35026.1 - 0.13 12.6 0.1 0.45 10.9 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 GAM35026.1 - 0.14 12.7 2.7 0.6 10.6 0.1 2.6 3 0 0 3 3 2 0 AAA domain UBA PF00627.31 GAM35026.1 - 0.14 12.1 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 UBA/TS-N domain HSM3_N PF18795.1 GAM35026.1 - 0.14 11.6 0.2 0.25 10.8 0.2 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, N terminal domain Phage_Nu1 PF07471.12 GAM35026.1 - 3 7.6 5.8 0.75 9.5 2.2 1.8 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 Cyclin_N PF00134.23 GAM35027.1 - 2.1e-45 153.6 0.4 3.8e-45 152.7 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAM35027.1 - 8.6e-33 113.0 0.1 2e-32 111.8 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.18 GAM35028.1 - 0.0016 18.5 12.0 0.0031 17.6 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpc4 PF05132.14 GAM35029.1 - 2.9e-31 108.9 0.0 2.9e-31 108.9 0.0 3.8 3 2 1 4 4 4 1 RNA polymerase III RPC4 CRCB PF02537.15 GAM35031.1 - 3.1e-39 133.2 10.6 9.7e-23 80.3 5.6 2.6 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Fungal_trans PF04082.18 GAM35032.1 - 1.5e-19 70.1 2.3 2.4e-19 69.4 2.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 GAM35032.1 - 7.6e-07 29.3 14.9 7.7e-05 22.9 5.5 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 GAM35032.1 - 0.00076 19.8 14.3 0.04 14.4 5.3 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 GAM35032.1 - 0.062 14.0 0.5 1.2 9.8 0.2 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 GAM35032.1 - 0.23 12.4 19.6 0.27 12.2 4.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAM35032.1 - 1.3 9.4 6.1 1.4 9.3 3.7 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 GAM35032.1 - 1.7 8.8 3.7 5.9 7.1 3.7 1.9 1 0 0 1 1 1 0 Zinc ribbon domain Amidohydro_3 PF07969.11 GAM35033.1 - 8e-80 269.6 0.7 9.3e-80 269.4 0.7 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 GAM35033.1 - 1.3e-09 37.8 0.0 1.3e-05 24.7 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family RasGEF PF00617.19 GAM35034.1 - 8.5e-59 198.7 0.0 1.7e-58 197.8 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM35034.1 - 1.7e-29 102.1 0.3 3.4e-29 101.1 0.3 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 GAM35034.1 - 1.8e-15 56.3 0.1 4e-15 55.1 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAM35034.1 - 2.3e-12 46.5 0.1 8.7e-12 44.7 0.1 2.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAM35034.1 - 1.4e-11 43.9 0.1 3.3e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 GAM35034.1 - 0.00026 21.0 0.1 0.002 18.2 0.0 2.3 2 0 0 2 2 2 1 WW domain DegS PF05384.11 GAM35034.1 - 0.0064 16.0 0.1 0.034 13.6 0.0 2.2 2 0 0 2 2 2 1 Sensor protein DegS JAB PF01398.21 GAM35035.1 - 1.2e-30 105.9 0.1 2.2e-30 105.1 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 GAM35035.1 - 3.7e-21 75.8 0.0 8.5e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 GAM35035.1 - 0.00019 21.2 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MAP65_ASE1 PF03999.12 GAM35036.1 - 5.3e-79 266.5 4.6 7.5e-79 266.0 4.6 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Fam20C PF06702.12 GAM35036.1 - 0.042 13.7 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 PWWP PF00855.17 GAM35036.1 - 0.14 12.6 0.0 0.42 11.0 0.0 1.8 1 0 0 1 1 1 0 PWWP domain DUF4407 PF14362.6 GAM35036.1 - 4.6 6.5 7.6 0.77 9.1 0.3 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) tRNA-synt_1c PF00749.21 GAM35037.1 - 1.5e-94 316.5 0.0 1.8e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain MFS_1 PF07690.16 GAM35038.1 - 7.5e-39 133.6 47.2 3.3e-38 131.5 41.8 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.12 GAM35038.1 - 0.0027 17.8 1.4 4.5 7.5 0.0 3.1 2 0 0 2 2 2 2 Poxvirus virion envelope protein A14 ILVD_EDD PF00920.21 GAM35039.1 - 1.2e-152 509.2 0.0 1.4e-152 509.0 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Glyco_transf_28 PF03033.20 GAM35041.1 - 2.9e-17 63.0 0.0 2.3e-16 60.1 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 GAM35041.1 - 2.7e-06 26.5 0.0 6.8e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 GAM35041.1 - 0.00062 20.1 0.0 0.0021 18.4 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain UIM PF02809.20 GAM35041.1 - 0.0021 17.9 3.7 0.0021 17.9 3.7 3.9 3 0 0 3 3 3 2 Ubiquitin interaction motif VPS13_C PF16909.5 GAM35041.1 - 0.0083 15.9 0.5 0.018 14.8 0.5 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Glyco_tran_28_C PF04101.16 GAM35041.1 - 0.044 13.8 0.2 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain PseudoU_synth_2 PF00849.22 GAM35042.1 - 1.7e-25 89.9 0.0 2.8e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 GAM35042.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 S4 domain Auto_anti-p27 PF06677.12 GAM35042.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GFA PF04828.14 GAM35042.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme DUF2757 PF10955.8 GAM35042.1 - 0.18 12.1 0.0 0.46 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) Ribosomal_L32e PF01655.18 GAM35043.1 - 5.7e-49 165.0 0.4 7e-49 164.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 HEAT PF02985.22 GAM35044.1 - 1.9e-05 24.5 7.3 1.8 9.0 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 GAM35044.1 - 0.0026 18.1 4.8 0.031 14.7 0.4 4.4 3 1 1 4 4 4 2 HEAT repeats BUD22 PF09073.10 GAM35044.1 - 0.0079 15.6 31.3 0.019 14.3 31.3 1.6 1 0 0 1 1 1 1 BUD22 Cnd1 PF12717.7 GAM35044.1 - 0.01 15.9 0.2 0.38 10.8 0.0 3.6 3 2 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Merozoite_SPAM PF07133.11 GAM35044.1 - 0.38 10.7 28.8 1.9 8.5 28.8 2.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop14 PF04147.12 GAM35044.1 - 0.57 8.3 36.0 0.26 9.5 33.3 1.8 2 0 0 2 2 2 0 Nop14-like family Cohesin_HEAT PF12765.7 GAM35044.1 - 0.98 9.8 3.1 4.2 7.8 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion SNF5 PF04855.12 GAM35045.1 - 1.2e-66 224.9 0.1 1.4e-65 221.4 0.1 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Exo_endo_phos PF03372.23 GAM35046.1 - 3.5e-07 30.0 0.0 5.8e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M24 PF00557.24 GAM35047.1 - 6.8e-09 35.7 0.0 1.3e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 NusA_N PF08529.11 GAM35047.1 - 1.1 9.6 5.5 4.4 7.7 1.2 2.7 2 1 0 2 2 2 0 NusA N-terminal domain PHD PF00628.29 GAM35048.1 - 3.7e-17 61.9 22.9 2.1e-11 43.5 8.7 2.5 2 0 0 2 2 2 2 PHD-finger Vps36-NZF-N PF16988.5 GAM35048.1 - 0.46 9.9 6.0 1.1 8.7 0.0 3.5 4 0 0 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-PHD-like PF15446.6 GAM35048.1 - 3.4 7.3 14.1 0.029 14.0 2.0 2.9 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Lectin_leg-like PF03388.13 GAM35049.1 - 2.3e-25 89.3 0.0 3.6e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family WES_acyltransf PF03007.16 GAM35049.1 - 0.061 13.1 1.3 0.094 12.5 1.3 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain COG5 PF10392.9 GAM35049.1 - 0.11 12.7 10.6 0.36 11.0 10.5 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 ATG16 PF08614.11 GAM35049.1 - 0.19 11.9 10.0 0.29 11.3 10.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 GAM35049.1 - 0.2 12.1 3.7 5.8 7.4 1.0 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.13 GAM35049.1 - 0.23 12.2 2.3 0.89 10.3 0.5 2.2 1 1 1 2 2 2 0 Occludin homology domain TBK1_CCD1 PF18394.1 GAM35049.1 - 0.3 10.6 4.4 0.44 10.1 4.4 1.2 1 0 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 ABC_tran_CTD PF16326.5 GAM35049.1 - 0.52 10.6 2.5 4.3 7.7 0.4 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain Fzo_mitofusin PF04799.13 GAM35049.1 - 4.4 6.8 9.3 11 5.5 6.6 2.1 1 1 1 2 2 2 0 fzo-like conserved region DUF4795 PF16043.5 GAM35049.1 - 6 6.4 9.6 20 4.7 9.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) HlyD_2 PF12700.7 GAM35049.1 - 8.4 5.0 8.6 3.4 6.3 0.2 2.1 1 1 1 2 2 2 0 HlyD family secretion protein Alg6_Alg8 PF03155.15 GAM35050.1 - 4.2e-169 563.6 31.8 4.9e-169 563.4 31.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.9 GAM35052.1 - 5.5e-40 136.0 0.3 1.7e-39 134.4 0.3 1.9 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 GAM35052.1 - 2.9e-24 85.4 0.2 2.9e-24 85.4 0.2 3.5 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif CCDC-167 PF15188.6 GAM35052.1 - 8.9 6.7 0.0 8.9 6.7 0.0 3.9 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 167 Mito_carr PF00153.27 GAM35053.1 - 3.2e-62 206.5 4.6 4.7e-21 74.5 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_2 PF08211.12 GAM35053.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region RRM_1 PF00076.22 GAM35054.1 - 0.0014 18.4 0.0 0.033 14.0 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BUD22 PF09073.10 GAM35054.1 - 5.8 6.1 31.5 0.25 10.7 18.8 2.1 2 0 0 2 2 2 0 BUD22 NMD3 PF04981.13 GAM35055.1 - 5.7e-81 271.6 5.4 7.8e-81 271.1 5.4 1.2 1 0 0 1 1 1 1 NMD3 family TackOD1 PF18551.1 GAM35055.1 - 0.12 12.0 5.8 0.65 9.7 1.8 2.5 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 GAM35055.1 - 1.6 8.8 11.7 6.2e+02 0.5 11.7 2.8 1 1 0 1 1 1 0 Double zinc ribbon FYVE_2 PF02318.16 GAM35055.1 - 3 8.1 6.4 15 5.8 2.6 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 GAM35055.1 - 5.3 7.3 10.8 19 5.5 4.9 2.7 2 1 0 2 2 2 0 FYVE zinc finger C1_1 PF00130.22 GAM35055.1 - 7.6 6.5 10.4 1.5 8.8 1.3 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Chordopox_G2 PF05796.12 GAM35056.1 - 0.064 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus protein G2 Pex2_Pex12 PF04757.14 GAM35057.1 - 8.6e-53 179.2 6.0 1.2e-52 178.7 6.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 GAM35057.1 - 2.6e-06 27.5 2.2 4.7e-06 26.7 2.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 GAM35057.1 - 0.00025 21.0 2.6 0.00025 21.0 2.6 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAM35057.1 - 0.00026 21.3 0.8 0.00054 20.2 0.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM35057.1 - 0.0014 18.5 2.1 0.0026 17.6 1.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM35057.1 - 0.0029 17.5 1.1 0.0053 16.6 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM35057.1 - 0.0031 17.3 0.7 0.0055 16.5 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_125 PF06824.11 GAM35058.1 - 2.8e-173 576.6 0.1 3.3e-173 576.4 0.1 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) CDC27 PF09507.10 GAM35059.1 - 9.8e-99 331.6 26.0 1.3e-98 331.2 26.0 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 SAP PF02037.27 GAM35060.1 - 6.8e-07 28.9 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain Sgf11 PF08209.11 GAM35060.1 - 0.028 14.0 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) MAS20 PF02064.15 GAM35060.1 - 8.3 6.5 6.0 2.7 8.1 1.9 2.0 2 0 0 2 2 2 0 MAS20 protein import receptor Snf7 PF03357.21 GAM35061.1 - 3.6e-19 69.0 19.8 4e-19 68.9 18.6 1.7 1 1 0 1 1 1 1 Snf7 Metalloenzyme PF01676.18 GAM35061.1 - 0.0087 15.4 0.2 0.011 15.2 0.2 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily MICSWaP PF17018.5 GAM35061.1 - 0.037 13.6 3.4 0.072 12.6 3.4 1.4 1 0 0 1 1 1 0 Spore wall protein Flu_M1_C PF08289.11 GAM35061.1 - 0.87 9.8 6.9 0.23 11.7 0.8 2.7 2 1 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain DUF4407 PF14362.6 GAM35061.1 - 6 6.1 15.8 0.86 8.9 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 GAM35061.1 - 7.8 7.1 8.3 1.6e+03 -0.4 8.2 3.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TRAPPC-Trs85 PF12739.7 GAM35062.1 - 2e-111 372.8 0.0 3.4e-111 372.1 0.0 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Tti2 PF10521.9 GAM35063.1 - 1.8e-79 267.2 3.1 2.2e-79 267.0 2.0 1.7 2 0 0 2 2 2 1 Tti2 family PolyA_pol PF01743.20 GAM35063.1 - 8.6e-26 90.8 0.1 2.6e-25 89.3 0.1 1.9 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 GAM35063.1 - 3.1e-07 30.1 0.0 1e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 GAM35063.1 - 0.061 13.3 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Syja_N PF02383.18 GAM35064.1 - 4.4e-78 262.8 0.0 7e-78 262.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Acyl-CoA_dh_1 PF00441.24 GAM35065.1 - 8.1e-31 107.3 0.4 1.2e-30 106.7 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAM35065.1 - 3.3e-26 92.2 0.0 7.8e-26 91.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAM35065.1 - 1.4e-23 82.8 0.1 2.5e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAM35065.1 - 1.8e-07 31.5 0.2 3.7e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.25 GAM35066.1 - 6.7e-35 120.7 0.0 2.6e-20 72.9 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM35066.1 - 1.5e-16 60.5 0.0 5.4e-06 25.9 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM35066.1 - 0.037 12.8 0.2 0.27 9.9 0.2 2.0 1 1 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 GAM35066.1 - 0.061 12.9 0.1 8 6.0 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 GAM35066.1 - 0.067 12.5 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.25 GAM35067.1 - 1.3e-38 132.5 0.4 1.9e-38 131.9 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35067.1 - 1.4e-30 106.6 1.3 3.6e-30 105.2 0.7 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM35067.1 - 1.4e-11 44.6 5.9 7.6e-10 39.0 3.2 3.8 3 1 0 3 3 3 1 KR domain Fungal_trans_2 PF11951.8 GAM35067.1 - 1.6e-07 30.5 0.2 2.5e-07 29.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM35067.1 - 6.5e-05 23.0 3.0 0.00011 22.3 3.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TrkA_N PF02254.18 GAM35067.1 - 0.044 14.0 0.1 0.09 13.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain YjeF_N PF03853.15 GAM35067.1 - 0.13 12.2 0.2 10 5.9 0.1 2.3 2 0 0 2 2 2 0 YjeF-related protein N-terminus adh_short PF00106.25 GAM35068.1 - 5.2e-20 71.7 0.0 5.3e-15 55.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35068.1 - 1.3e-14 54.3 0.0 2.9e-11 43.4 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM35068.1 - 0.00036 20.5 0.0 0.00079 19.4 0.0 1.5 2 0 0 2 2 2 1 KR domain Fungal_trans PF04082.18 GAM35069.1 - 0.0026 16.8 0.0 0.0035 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 GAM35070.1 - 1.2e-13 50.7 0.7 1.9e-13 50.1 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNA_pol_B_exo1 PF03104.19 GAM35071.1 - 2.8e-84 283.2 0.0 3.3e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.6 GAM35071.1 - 0.01 15.9 0.3 0.066 13.2 0.3 2.3 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 GAM35071.1 - 0.051 13.2 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B PF00136.21 GAM35072.1 - 1.8e-149 498.4 3.7 2.2e-149 498.1 3.7 1.1 1 0 0 1 1 1 1 DNA polymerase family B C1_1 PF00130.22 GAM35072.1 - 0.024 14.5 0.6 0.049 13.5 0.6 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SwrA PF17423.2 GAM35072.1 - 0.12 12.3 0.7 0.86 9.6 0.0 2.7 3 0 0 3 3 3 0 Swarming motility protein zf-C4pol PF14260.6 GAM35072.1 - 0.14 12.7 0.1 0.33 11.4 0.1 1.7 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DUF2076 PF09849.9 GAM35075.1 - 0.0026 17.9 0.4 0.0027 17.8 0.4 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Cyanate_lyase PF02560.14 GAM35076.1 - 2.7e-32 110.4 0.0 3.8e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain PLDc_2 PF13091.6 GAM35077.1 - 8.3e-17 61.3 0.0 6e-06 26.2 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 GAM35077.1 - 2e-12 46.7 1.1 4.8e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Kinetochor_Ybp2 PF08568.10 GAM35078.1 - 3.7e-139 465.1 0.4 4.3e-139 464.9 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Rhomboid PF01694.22 GAM35079.1 - 1.4e-34 119.2 10.8 3.1e-34 118.1 10.8 1.6 1 0 0 1 1 1 1 Rhomboid family DUF2177 PF09945.9 GAM35079.1 - 0.1 12.7 4.5 0.18 11.9 0.8 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2177) DHHC PF01529.20 GAM35080.1 - 6.8e-38 129.8 8.5 9.2e-38 129.4 8.5 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase APC_u15 PF16636.5 GAM35080.1 - 6 7.4 5.6 2.1 8.8 0.9 2.3 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 UQ_con PF00179.26 GAM35081.1 - 6.7e-18 64.7 0.0 1.1e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAM35081.1 - 0.026 14.8 0.0 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 RWD domain SOG2 PF10428.9 GAM35081.1 - 0.043 13.0 7.8 0.054 12.7 7.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Podoplanin PF05808.11 GAM35081.1 - 0.084 13.0 4.7 0.14 12.2 4.7 1.4 1 1 0 1 1 1 0 Podoplanin Prok-E2_A PF14457.6 GAM35081.1 - 0.11 12.1 0.1 0.25 10.9 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family A Chlam_PMP PF02415.17 GAM35081.1 - 4.8 7.9 7.6 5.4 7.7 5.7 2.1 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat B-block_TFIIIC PF04182.12 GAM35082.1 - 9.8e-19 67.3 0.2 5e-18 65.0 0.0 2.3 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MarR PF01047.22 GAM35082.1 - 0.0072 16.2 0.4 0.94 9.5 0.0 2.8 2 0 0 2 2 2 2 MarR family SAM_2 PF07647.17 GAM35082.1 - 0.13 12.4 0.2 13 6.0 0.0 2.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Chloroplast_duf PF14476.6 GAM35083.1 - 0.03 13.3 0.0 0.03 13.3 0.0 1.0 1 0 0 1 1 1 0 Petal formation-expressed p450 PF00067.22 GAM35084.1 - 1.3e-66 225.3 0.0 1.9e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 GAM35087.1 - 2e-09 37.2 0.0 2.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35087.1 - 0.019 14.6 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Tannase PF07519.11 GAM35088.1 - 1.2e-102 344.3 2.2 2.6e-102 343.2 2.2 1.5 1 1 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 GAM35088.1 - 0.011 15.0 0.0 0.22 10.8 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAM35088.1 - 0.022 14.3 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Shikimate_dh_N PF08501.11 GAM35089.1 - 9.1e-18 64.3 0.0 1.7e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain DSPc PF00782.20 GAM35089.1 - 0.096 12.5 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain SDH_C PF18317.1 GAM35089.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain AP_endonuc_2 PF01261.24 GAM35090.1 - 3.8e-27 95.1 0.0 5.3e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Zn_clus PF00172.18 GAM35091.1 - 4.5e-10 39.5 11.5 7.5e-10 38.8 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM35091.1 - 0.00047 19.3 2.1 0.0022 17.1 2.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Shikimate_dh_N PF08501.11 GAM35092.1 - 1.9e-17 63.3 0.0 5.7e-17 61.8 0.0 1.8 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 GAM35092.1 - 2.1e-16 60.4 0.0 4.3e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase DHquinase_I PF01487.15 GAM35092.1 - 1.1e-14 55.2 0.0 2.4e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SDH_C PF18317.1 GAM35092.1 - 2e-08 33.9 0.0 3.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 GAM35092.1 - 3e-08 33.8 0.0 9e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 GAM35092.1 - 0.0029 18.2 0.0 0.011 16.3 0.0 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 GAM35092.1 - 0.017 15.3 0.0 0.046 14.0 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain OCD_Mu_crystall PF02423.15 GAM35092.1 - 0.064 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DUF755 PF05501.11 GAM35092.1 - 0.36 11.1 2.5 0.97 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DHquinase_II PF01220.19 GAM35093.1 - 8.7e-64 213.3 0.6 9.8e-64 213.2 0.6 1.0 1 0 0 1 1 1 1 Dehydroquinase class II GFO_IDH_MocA PF01408.22 GAM35094.1 - 4.2e-15 56.6 0.0 6.5e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PhyH PF05721.13 GAM35095.1 - 4.3e-09 36.9 0.0 4.3e-08 33.7 0.0 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_3 PF00933.21 GAM35096.1 - 6.3e-49 167.1 0.0 8.4e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain NDT80_PhoG PF05224.12 GAM35096.1 - 9.1e-16 58.6 0.0 2.3e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Acetyltransf_1 PF00583.25 GAM35096.1 - 1.9e-06 28.1 0.0 6.4e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM35096.1 - 0.00059 20.2 0.0 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM35096.1 - 0.00062 19.7 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM35096.1 - 0.046 13.9 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Melibiase_2 PF16499.5 GAM35097.1 - 9.5e-60 202.2 2.3 1.9e-59 201.2 2.3 1.5 1 1 0 1 1 1 1 Alpha galactosidase A Ricin_B_lectin PF00652.22 GAM35097.1 - 1.3e-13 51.3 2.0 2.1e-13 50.6 2.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Melibiase_C PF17801.1 GAM35097.1 - 2e-11 43.8 0.2 9.7e-11 41.6 0.1 2.3 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 GAM35097.1 - 0.004 16.2 0.0 0.0068 15.4 0.0 1.3 1 0 0 1 1 1 1 Melibiase RicinB_lectin_2 PF14200.6 GAM35097.1 - 0.078 13.7 4.9 0.17 12.6 0.4 2.5 1 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like LprI PF07007.12 GAM35098.1 - 0.023 15.3 0.1 0.03 15.0 0.1 1.2 1 0 0 1 1 1 0 Lysozyme inhibitor LprI Fungal_trans PF04082.18 GAM35099.1 - 2.2e-10 40.0 1.2 4.2e-10 39.1 1.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM35099.1 - 5.8e-08 32.7 8.1 9.8e-08 32.0 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Esterase_phd PF10503.9 GAM35100.1 - 1.2e-16 60.9 0.5 1.2e-16 60.9 0.5 1.6 2 0 0 2 2 2 1 Esterase PHB depolymerase CBM_1 PF00734.18 GAM35100.1 - 2.5e-13 49.7 12.7 1.2e-12 47.6 12.7 2.3 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 GAM35100.1 - 2e-08 34.0 1.3 3.1e-08 33.4 1.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 GAM35100.1 - 0.017 14.8 0.9 0.029 14.0 0.9 1.4 1 1 0 1 1 1 0 Putative esterase Sporozoite_P67 PF05642.11 GAM35100.1 - 0.075 11.1 3.9 0.064 11.3 3.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen 3Beta_HSD PF01073.19 GAM35101.1 - 3.9e-16 58.9 0.0 5.1e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM35101.1 - 6.2e-16 58.6 0.0 8.2e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM35101.1 - 1.9e-09 37.6 0.5 4.1e-09 36.6 0.5 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 GAM35101.1 - 4.4e-09 35.9 0.1 9.7e-09 34.8 0.1 1.6 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 GAM35101.1 - 2.3e-06 27.2 1.1 0.00013 21.5 0.1 2.7 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAM35101.1 - 3.2e-06 26.9 0.0 1.7e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 GAM35101.1 - 0.0072 16.2 0.2 0.061 13.2 0.1 2.0 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 GAM35101.1 - 0.016 14.7 0.1 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase Shikimate_DH PF01488.20 GAM35101.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 GAM35102.1 - 4.5e-12 46.0 0.0 6.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM35102.1 - 1.7e-10 41.1 0.3 3.4e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding DapB_N PF01113.20 GAM35102.1 - 4.2e-05 23.7 0.2 7.3e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 GAM35102.1 - 0.0031 17.0 0.1 0.007 15.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 GAM35102.1 - 0.0058 16.5 0.1 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein F420_oxidored PF03807.17 GAM35102.1 - 0.006 17.1 0.4 0.013 16.1 0.4 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 GAM35102.1 - 0.006 16.5 0.2 0.0098 15.8 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAM35102.1 - 0.0096 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 GAM35102.1 - 0.05 13.7 0.1 0.085 12.9 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KR PF08659.10 GAM35102.1 - 0.056 13.4 0.2 0.088 12.7 0.2 1.3 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.18 GAM35102.1 - 0.066 13.5 0.3 0.2 12.0 0.3 1.8 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 GAM35102.1 - 0.085 13.0 0.6 0.29 11.3 0.6 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 GAM35102.1 - 0.096 12.1 1.2 0.47 9.9 1.3 1.9 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_7 PF13241.6 GAM35102.1 - 0.15 12.5 0.1 0.53 10.8 0.1 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF1365 PF07103.11 GAM35103.1 - 0.00083 19.1 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Fungal_trans PF04082.18 GAM35104.1 - 3e-05 23.2 0.0 4.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_11 PF00457.17 GAM35105.1 - 1.3e-48 165.0 18.0 1.3e-48 165.0 18.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 GAM35105.1 - 5.7e-14 51.8 13.3 5.7e-14 51.8 13.3 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF515 PF04415.12 GAM35105.1 - 2.5 6.4 7.5 3.2 6.0 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SIMPL PF04402.14 GAM35106.1 - 2.1e-17 64.3 0.0 2.5e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Transcrip_reg PF01709.20 GAM35106.1 - 0.04 13.3 0.1 0.061 12.7 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator Sugar_tr PF00083.24 GAM35107.1 - 2.8e-11 43.0 0.2 4.5e-11 42.3 0.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 GAM35108.1 - 1.6e-98 330.5 24.1 1.9e-98 330.3 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM35108.1 - 1.7e-16 60.1 50.4 9.1e-16 57.7 25.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 GAM35109.1 - 1.3e-06 28.4 9.1 2.3e-06 27.6 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAM35109.1 - 0.00051 19.0 0.0 0.00099 18.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 GAM35110.1 - 9.7e-102 341.1 26.9 1.2e-101 340.9 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM35110.1 - 1.5e-27 96.5 17.8 1.5e-27 96.5 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.12 GAM35111.1 - 2e-30 104.9 0.8 3.8e-30 104.0 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM35111.1 - 1.7e-22 79.8 0.0 2.7e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAM35111.1 - 2.9e-06 26.9 0.1 7.4e-05 22.3 0.1 2.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Methyltransf_25 PF13649.6 GAM35111.1 - 0.0006 20.5 0.0 0.0014 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 GAM35111.1 - 0.00077 20.5 0.0 0.0055 17.7 0.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 GAM35111.1 - 0.017 14.9 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 GAM35111.1 - 0.037 13.4 0.4 0.061 12.7 0.4 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AlaDh_PNT_C PF01262.21 GAM35111.1 - 0.053 12.8 0.1 0.082 12.2 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAM35111.1 - 0.053 12.9 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 GAM35111.1 - 0.068 13.8 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAM35111.1 - 0.14 11.7 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase small domain adh_short_C2 PF13561.6 GAM35112.1 - 5.3e-62 209.4 0.8 6.4e-62 209.2 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM35112.1 - 2.5e-42 144.6 0.5 3e-42 144.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM35112.1 - 3.2e-15 56.5 0.4 4.3e-15 56.1 0.4 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 GAM35112.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus adh_short_C2 PF13561.6 GAM35113.1 - 9.6e-58 195.5 3.9 1.2e-57 195.2 3.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM35113.1 - 1.6e-40 138.7 4.2 1.9e-40 138.4 4.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM35113.1 - 2.3e-14 53.7 1.4 3.2e-14 53.2 1.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM35113.1 - 0.0032 17.0 1.8 0.013 15.0 1.8 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 GAM35113.1 - 0.044 14.4 0.6 0.12 13.0 0.6 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_trans_4_4 PF13579.6 GAM35113.1 - 0.072 13.5 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Peripla_BP_4 PF13407.6 GAM35113.1 - 0.14 11.7 5.5 0.33 10.5 5.4 1.7 1 1 0 1 1 1 0 Periplasmic binding protein domain Asparaginase PF00710.20 GAM35114.1 - 6.5e-50 169.4 0.8 1.1e-49 168.6 0.8 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 GAM35114.1 - 6.7e-20 71.4 0.0 1.5e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_3 PF13606.6 GAM35115.1 - 7.7e-10 38.2 0.2 1.8e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 GAM35115.1 - 5.8e-09 36.0 0.3 8.6e-06 26.0 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 GAM35115.1 - 8.6e-09 35.9 0.0 1.4e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM35115.1 - 3.6e-07 30.3 0.6 3.7e-05 23.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM35115.1 - 5.1e-06 26.9 0.1 0.0007 20.1 0.1 2.3 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ketoacyl-synt_C PF02801.22 GAM35117.1 - 7.9e-29 100.1 0.4 1.2e-28 99.5 0.4 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 GAM35117.1 - 8.9e-29 100.8 0.6 1.2e-28 100.3 0.2 1.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 GAM35117.1 - 0.0011 18.8 0.2 0.0033 17.2 0.0 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 GAM35117.1 - 0.013 14.3 0.2 0.048 12.3 0.0 1.9 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Thiolase_N PF00108.23 GAM35117.1 - 0.021 14.2 0.4 0.032 13.6 0.3 1.4 1 1 0 1 1 1 0 Thiolase, N-terminal domain DUF2235 PF09994.9 GAM35118.1 - 4.7e-80 269.0 0.0 6e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_3 PF07859.13 GAM35118.1 - 3.9e-17 62.8 0.0 1.1e-16 61.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAM35118.1 - 1.2e-07 31.0 0.0 2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase An_peroxidase PF03098.15 GAM35119.1 - 9.8e-36 123.4 0.0 6.9e-21 74.4 0.0 3.8 1 1 2 3 3 3 3 Animal haem peroxidase GMC_oxred_N PF00732.19 GAM35120.1 - 4.7e-33 114.8 0.0 1.7e-29 103.1 0.0 3.0 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM35120.1 - 3.7e-30 105.4 0.0 7.3e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 GAM35120.1 - 4.2e-05 23.7 0.0 0.0001 22.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM35120.1 - 7.8e-05 22.0 0.0 0.00043 19.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM35120.1 - 0.00033 19.8 0.1 0.0077 15.3 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 GAM35120.1 - 0.00058 19.2 0.0 0.69 9.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 GAM35120.1 - 0.0032 17.1 0.0 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 GAM35120.1 - 0.013 15.1 0.0 0.28 10.7 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAM35120.1 - 0.027 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.21 GAM35120.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.14 GAM35120.1 - 0.11 11.2 0.1 0.18 10.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 GAM35120.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Solute_trans_a PF03619.16 GAM35121.1 - 5.5e-57 193.3 23.3 3.1e-56 190.9 24.8 1.4 2 0 0 2 2 2 1 Organic solute transporter Ostalpha CitMHS PF03600.16 GAM35121.1 - 4 6.5 6.3 73 2.4 6.3 2.1 1 1 0 1 1 1 0 Citrate transporter DUF1980 PF09323.10 GAM35121.1 - 4.7 7.1 12.3 5.7 6.8 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1980) p450 PF00067.22 GAM35122.1 - 5.8e-32 111.0 0.0 8e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BBE PF08031.12 GAM35122.1 - 0.00055 20.0 0.1 0.0012 18.9 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_2 PF00891.18 GAM35123.1 - 6.8e-22 77.8 0.0 1.2e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 GAM35123.1 - 0.049 14.3 0.0 0.15 12.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain p450 PF00067.22 GAM35125.1 - 5.2e-58 196.9 0.0 6.2e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fumble PF03630.14 GAM35125.1 - 0.029 13.5 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 Fumble MLTR_LBD PF17765.1 GAM35125.1 - 0.032 14.4 0.1 0.076 13.1 0.1 1.7 1 1 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain p450 PF00067.22 GAM35127.1 - 7e-61 206.4 0.0 9.3e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transketolase_N PF00456.21 GAM35128.1 - 8.5e-72 241.9 0.1 7.6e-32 110.6 0.0 3.1 2 1 1 3 3 3 3 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAM35128.1 - 2.3e-30 105.6 0.0 1.2e-28 100.0 0.0 2.4 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAM35128.1 - 0.0076 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain MFS_1 PF07690.16 GAM35129.1 - 2.1e-11 43.4 27.8 2.1e-11 43.4 27.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAM35129.1 - 9.1e-10 38.5 3.0 2.2e-09 37.2 2.3 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 GAM35129.1 - 0.00091 18.2 5.6 0.00091 18.2 5.6 3.2 3 0 0 3 3 3 1 Sugar (and other) transporter DAO PF01266.24 GAM35130.1 - 1.5e-38 133.3 0.0 1.7e-38 133.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM35130.1 - 2.6e-05 23.6 0.0 0.15 11.2 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM35130.1 - 0.016 15.2 0.3 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Epimerase PF01370.21 GAM35130.1 - 0.07 12.6 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 GAM35130.1 - 0.096 13.3 0.1 0.37 11.4 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.23 GAM35130.1 - 0.11 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain GIDA PF01134.22 GAM35130.1 - 0.13 11.3 0.0 3.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A GST_N_3 PF13417.6 GAM35131.1 - 1.4e-07 31.8 0.0 2.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM35131.1 - 1.9e-07 31.3 0.0 3.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM35131.1 - 0.00027 20.9 0.0 0.00052 20.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM35131.1 - 0.0012 19.0 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM35131.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BNR_2 PF13088.6 GAM35132.1 - 5.1e-05 22.7 0.2 0.0045 16.3 0.1 2.6 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 GAM35132.1 - 0.00064 19.4 6.3 0.14 12.2 0.2 3.9 3 0 0 3 3 3 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 GAM35132.1 - 0.0017 17.2 0.1 6.4 5.5 0.0 2.9 2 1 0 2 2 2 1 Sortilin, neurotensin receptor 3, F5_F8_type_C PF00754.25 GAM35132.1 - 0.022 14.9 1.0 4 7.6 0.1 3.2 4 0 0 4 4 4 0 F5/8 type C domain BNR_6 PF15899.5 GAM35132.1 - 0.04 14.0 2.9 4.3 7.7 0.2 3.1 3 0 0 3 3 3 0 BNR-Asp box repeat FAD_binding_3 PF01494.19 GAM35133.1 - 9.9e-22 77.6 0.0 6.1e-21 75.1 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM35133.1 - 0.0027 17.9 0.1 0.0055 16.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM35133.1 - 0.015 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM35133.1 - 0.015 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 GAM35133.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 GAM35134.1 - 5.2e-33 114.4 37.9 9.9e-33 113.5 37.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM35134.1 - 3.7e-22 78.6 1.2 7.9e-22 77.6 1.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 GAM35134.1 - 1.7e-09 37.1 21.4 4e-09 35.9 20.7 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 GAM35134.1 - 0.066 12.1 11.8 0.015 14.1 7.7 2.0 2 0 0 2 2 2 0 MFS_1 like family Big_6 PF17936.1 GAM35134.1 - 0.24 11.7 1.1 0.53 10.6 1.1 1.5 1 0 0 1 1 1 0 Bacterial Ig domain DUF21 PF01595.20 GAM35134.1 - 1.5 8.5 4.9 3.9 7.2 4.9 1.7 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain Abhydrolase_3 PF07859.13 GAM35135.1 - 2.8e-38 131.9 0.2 1.4e-21 77.4 0.0 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 GAM35135.1 - 2.1e-06 26.9 0.0 2.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 GAM35135.1 - 0.081 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Sugar_tr PF00083.24 GAM35136.1 - 9.3e-79 265.4 32.5 2e-62 211.6 15.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM35136.1 - 6.6e-17 61.5 45.0 1.5e-08 33.9 21.2 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TctC PF03401.14 GAM35136.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor SDH_alpha PF03313.15 GAM35136.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine dehydratase alpha chain Fe-ADH PF00465.19 GAM35137.1 - 9.1e-40 136.6 0.0 1.5e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 GAM35137.1 - 2.3e-09 37.4 0.0 2.2e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase FMO-like PF00743.19 GAM35138.1 - 8.8e-17 60.7 2.4 5.5e-16 58.1 1.2 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 GAM35138.1 - 6.4e-09 35.9 0.0 1.6e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAM35138.1 - 7.5e-07 28.6 0.2 7.8e-05 22.0 0.0 3.3 3 1 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 GAM35138.1 - 0.0034 16.7 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM35138.1 - 0.013 15.5 0.2 0.78 9.7 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAM35138.1 - 0.067 12.4 0.1 0.23 10.7 0.0 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Nup84_Nup100 PF04121.13 GAM35138.1 - 0.17 10.0 0.1 0.23 9.5 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 AMP-binding PF00501.28 GAM35139.1 - 3.6e-73 246.6 0.0 4.4e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM35139.1 - 2.1e-17 63.9 0.0 4.3e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ins134_P3_kin_N PF17927.1 GAM35139.1 - 0.035 14.5 0.1 0.12 12.8 0.1 1.9 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Aldedh PF00171.22 GAM35140.1 - 3.6e-118 395.0 2.5 6.9e-116 387.5 2.5 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF1344 PF07076.11 GAM35140.1 - 0.1 12.5 0.0 18 5.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) GTP_cyclohydro2 PF00925.20 GAM35140.1 - 0.17 11.5 0.0 1.7 8.2 0.0 2.4 2 1 0 2 2 2 0 GTP cyclohydrolase II MFS_1 PF07690.16 GAM35141.1 - 9.1e-26 90.6 41.0 4.1e-24 85.2 12.5 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM35141.1 - 2.4e-19 69.4 0.0 5.3e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4718 PF15842.5 GAM35141.1 - 0.072 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) PDZ_assoc PF10600.9 GAM35141.1 - 2 9.3 5.2 44 5.0 0.6 3.4 3 0 0 3 3 3 0 PDZ-associated domain of NMDA receptors Peptidase_M19 PF01244.21 GAM35142.1 - 2e-70 237.5 0.0 2.5e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) p450 PF00067.22 GAM35143.1 - 5.2e-20 71.6 0.0 1.4e-17 63.6 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 Rick_17kDa_Anti PF05433.15 GAM35144.1 - 0.036 13.9 15.3 0.036 13.9 15.3 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain GRDP-like PF07173.12 GAM35145.1 - 4.1e-16 59.9 4.5 1.3e-12 48.6 0.1 3.1 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like DUF1690 PF07956.11 GAM35145.1 - 0.32 11.4 3.0 0.76 10.2 3.0 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Fungal_trans PF04082.18 GAM35146.1 - 1.1e-07 31.2 0.2 2e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM35146.1 - 1.7e-07 31.2 8.3 3.8e-07 30.1 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2236 PF09995.9 GAM35147.1 - 1.2e-53 182.7 0.6 1.5e-53 182.3 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF3712 PF12505.8 GAM35148.1 - 2.4e-32 111.8 1.8 5.4e-32 110.7 0.5 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 GAM35148.1 - 0.03 14.9 0.2 0.23 12.0 0.1 2.4 3 0 0 3 3 3 0 Late embryogenesis abundant protein AMP-binding PF00501.28 GAM35149.1 - 3.1e-50 171.0 0.0 3.7e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM35149.1 - 1.5e-16 61.2 0.3 3.6e-16 59.9 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2236 PF09995.9 GAM35150.1 - 1.2e-32 114.0 0.0 1.6e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Abhydrolase_1 PF00561.20 GAM35152.1 - 5e-23 82.1 0.0 7.3e-22 78.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM35152.1 - 1.2e-13 52.2 0.0 1.6e-13 51.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM35152.1 - 2.7e-06 26.9 0.0 0.00032 20.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Pro_CA PF00484.19 GAM35153.1 - 5.4e-12 46.3 0.2 2e-11 44.4 0.2 1.8 1 1 0 1 1 1 1 Carbonic anhydrase Fungal_trans PF04082.18 GAM35154.1 - 5.6e-10 38.7 0.0 6.3e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain She9_MDM33 PF05546.11 GAM35154.1 - 0.061 13.1 0.0 0.22 11.3 0.0 1.8 1 1 0 1 1 1 0 She9 / Mdm33 family MFS_1 PF07690.16 GAM35155.1 - 5.9e-12 45.2 54.3 8e-10 38.2 52.9 3.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM35155.1 - 1e-05 24.2 23.3 1.5e-05 23.7 23.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5336 PF17270.2 GAM35155.1 - 1.5 8.5 4.8 16 5.1 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5336) DUF3425 PF11905.8 GAM35156.1 - 6.3e-16 58.5 0.0 1.2e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 GAM35156.1 - 0.23 11.6 3.6 0.44 10.7 3.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor NmrA PF05368.13 GAM35157.1 - 1.4e-36 126.2 0.2 1.9e-36 125.8 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM35157.1 - 4.2e-11 43.1 0.1 6.8e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM35157.1 - 2.7e-05 23.7 0.0 5.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM35157.1 - 0.00035 19.7 0.0 0.00047 19.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 GAM35157.1 - 0.01 16.1 0.1 0.02 15.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 GAM35157.1 - 0.088 13.1 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FXMRP1_C_core PF12235.8 GAM35159.1 - 0.5 11.0 5.9 0.48 11.1 0.5 2.3 1 1 0 2 2 2 0 Fragile X-related 1 protein core C terminal Glyco_hydro_18 PF00704.28 GAM35160.1 - 1.2e-66 225.6 0.0 1.4e-66 225.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NmrA PF05368.13 GAM35161.1 - 1.4e-41 142.5 0.0 2.4e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM35161.1 - 2.9e-16 59.9 0.1 4.6e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF1048 PF06304.11 GAM35161.1 - 0.082 13.4 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) Guanylate_kin PF00625.21 GAM35161.1 - 0.16 11.6 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Guanylate kinase FAD_binding_3 PF01494.19 GAM35162.1 - 1.4e-07 31.1 0.0 1.5e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 GAM35162.1 - 0.00064 19.7 0.5 0.027 14.5 0.2 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAM35162.1 - 0.02 15.1 0.1 0.047 13.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Fungal_trans PF04082.18 GAM35163.1 - 8.2e-09 34.9 0.0 2e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Mid2 PF04478.12 GAM35164.1 - 0.00092 19.1 0.0 0.00097 19.0 0.0 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor ISK_Channel PF02060.15 GAM35164.1 - 0.0096 15.6 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Slow voltage-gated potassium channel Amnionless PF14828.6 GAM35164.1 - 0.016 14.1 0.0 0.016 14.0 0.0 1.0 1 0 0 1 1 1 0 Amnionless DUF4448 PF14610.6 GAM35164.1 - 0.016 15.0 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TAS2R PF05296.13 GAM35164.1 - 0.036 13.2 0.0 0.037 13.1 0.0 1.0 1 0 0 1 1 1 0 Taste receptor protein (TAS2R) Orf78 PF06024.12 GAM35164.1 - 0.051 13.9 0.0 0.069 13.5 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) GWT1 PF06423.12 GAM35164.1 - 0.052 13.7 0.0 0.066 13.3 0.0 1.1 1 0 0 1 1 1 0 GWT1 PspB PF06667.12 GAM35164.1 - 0.054 13.5 0.2 0.089 12.9 0.2 1.4 1 1 0 1 1 1 0 Phage shock protein B ABC2_membrane_3 PF12698.7 GAM35164.1 - 0.061 12.4 0.0 0.078 12.1 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF485 PF04341.12 GAM35164.1 - 0.067 13.1 0.4 0.11 12.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Herpes_gE PF02480.16 GAM35164.1 - 0.25 10.1 0.0 0.26 10.0 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NmrA PF05368.13 GAM35165.1 - 2.3e-09 37.2 0.0 6.4e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM35165.1 - 1e-06 28.7 0.0 3.5e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding Homeodomain PF00046.29 GAM35166.1 - 2.4e-14 52.9 1.3 2.4e-14 52.9 1.3 1.9 2 0 0 2 2 2 1 Homeodomain CBM_4_9 PF02018.17 GAM35167.1 - 0.72 10.1 11.4 0.2 11.9 7.1 2.3 2 1 0 2 2 2 0 Carbohydrate binding domain Amino_oxidase PF01593.24 GAM35168.1 - 3.2e-49 168.5 2.5 1.2e-47 163.3 2.5 2.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM35168.1 - 5.4e-17 61.8 0.3 1.4e-16 60.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM35168.1 - 2.2e-06 27.1 0.1 1.7e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM35168.1 - 1.1e-05 25.9 0.9 2.4e-05 24.8 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM35168.1 - 1.8e-05 24.5 3.5 0.00019 21.1 3.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAM35168.1 - 9.5e-05 21.7 0.5 0.00015 21.1 0.5 1.2 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 GAM35168.1 - 0.00012 21.4 0.1 0.00022 20.6 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 GAM35168.1 - 0.00017 21.0 0.3 0.00029 20.3 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM35168.1 - 0.00018 20.3 0.7 0.00018 20.3 0.7 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 GAM35168.1 - 0.0019 17.4 1.5 0.0028 16.8 1.5 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAM35168.1 - 0.0025 17.1 0.3 0.0038 16.5 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 GAM35168.1 - 0.0072 16.3 1.6 1.4 8.9 0.6 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding 3HCDH_N PF02737.18 GAM35168.1 - 0.017 15.0 0.8 0.03 14.2 0.8 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 GAM35168.1 - 0.061 12.6 2.6 0.23 10.7 1.6 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM35168.1 - 0.14 11.3 2.4 0.19 10.8 1.3 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 GAM35168.1 - 0.16 11.3 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 GAM35169.1 - 1.8e-94 317.2 0.0 2e-94 317.0 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAM35169.1 - 2.4e-08 33.6 0.5 4e-08 32.9 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 GAM35169.1 - 1.2e-06 28.1 0.0 1.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM35169.1 - 1.5e-06 28.4 1.9 2.4e-06 27.7 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM35169.1 - 9.5e-06 25.4 1.9 3.4e-05 23.6 1.7 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 GAM35169.1 - 1.7e-05 24.1 0.3 1.7e-05 24.1 0.3 2.2 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 GAM35169.1 - 1.8e-05 24.2 0.7 0.00018 20.9 0.2 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM35169.1 - 0.00045 19.0 1.4 0.0012 17.6 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 GAM35169.1 - 0.00066 19.0 0.3 0.0023 17.2 0.2 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 GAM35169.1 - 0.0031 18.0 1.9 0.016 15.7 0.4 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM35169.1 - 0.0047 16.0 0.3 0.0075 15.4 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAM35169.1 - 0.017 14.4 0.1 0.039 13.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAM35169.1 - 0.046 13.0 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 GAM35169.1 - 0.079 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Cytidylate_kin PF02224.18 GAM35169.1 - 0.08 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase DUF2235 PF09994.9 GAM35171.1 - 2.4e-100 335.6 0.1 3e-100 335.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF896 PF05979.12 GAM35171.1 - 0.0076 16.1 0.4 0.026 14.4 0.4 1.9 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF896) An_peroxidase PF03098.15 GAM35172.1 - 6.3e-39 133.9 0.1 8.6e-26 90.6 0.0 3.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 GAM35172.1 - 5.4e-08 32.0 0.0 1.3e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Mus7 PF09462.10 GAM35173.1 - 5.5e-179 597.0 0.4 8e-179 596.4 0.4 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family FAD_binding_3 PF01494.19 GAM35174.1 - 1.7e-18 67.0 0.9 2.1e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAM35174.1 - 4.3e-07 30.1 0.2 9.4e-07 29.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM35174.1 - 9e-07 28.4 0.2 1.5e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAM35174.1 - 5.9e-05 22.6 0.8 9.4e-05 21.9 0.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 GAM35174.1 - 7.2e-05 22.5 6.7 0.00021 21.0 4.4 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM35174.1 - 0.00019 20.7 0.1 0.00027 20.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GAM35174.1 - 0.021 15.4 0.6 0.021 15.4 0.6 2.2 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM35174.1 - 0.025 13.3 1.1 0.04 12.6 1.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 GAM35174.1 - 0.025 13.7 0.7 0.05 12.7 0.7 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 GAM35174.1 - 0.04 13.2 0.6 0.1 11.9 0.2 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 GAM35174.1 - 0.052 12.4 0.5 3.1 6.5 0.9 2.1 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 GAM35174.1 - 0.13 11.5 0.4 0.42 9.9 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 GAM35174.1 - 4.1 6.6 6.1 0.49 9.6 1.0 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Amidohydro_2 PF04909.14 GAM35175.1 - 1.1e-34 120.6 0.4 1.4e-34 120.3 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase Abhydrolase_6 PF12697.7 GAM35176.1 - 3.1e-15 57.4 0.0 4.1e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAPA-1 PF04795.12 GAM35177.1 - 3.2e-25 88.7 6.9 3.2e-25 88.7 6.9 3.8 2 2 1 3 3 3 1 PAPA-1-like conserved region Pex14_N PF04695.13 GAM35178.1 - 2.2e-40 138.9 0.3 2.2e-40 138.9 0.3 2.4 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SRA1 PF07304.11 GAM35179.1 - 2.8e-11 43.4 0.3 2.8e-11 43.4 0.3 3.7 4 1 0 4 4 4 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 GAM35179.1 - 3.1e-09 37.3 4.4 1.4 9.9 0.0 6.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM35179.1 - 0.00032 20.9 0.1 0.0024 18.1 0.0 2.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Prp18 PF02840.15 GAM35179.1 - 0.02 14.9 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 Prp18 domain Sec16_C PF12931.7 GAM35179.1 - 0.023 14.3 0.0 0.21 11.2 0.0 2.2 1 1 0 1 1 1 0 Sec23-binding domain of Sec16 RRM_1 PF00076.22 GAM35180.1 - 5.4e-17 61.4 0.1 1e-16 60.5 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM35180.1 - 0.003 17.6 0.0 0.0042 17.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 GAM35180.1 - 0.095 12.7 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif B12D PF06522.11 GAM35181.1 - 0.00051 19.8 0.0 0.00078 19.2 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX6B PF02297.17 GAM35182.1 - 6.2e-18 64.8 5.6 7.3e-18 64.6 5.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 GAM35182.1 - 0.01 15.8 1.9 0.016 15.2 1.7 1.4 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 GAM35182.1 - 0.034 14.1 1.0 0.057 13.4 0.9 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain T2SSJ PF11612.8 GAM35182.1 - 0.09 13.0 0.2 1.3 9.2 0.2 2.0 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein J Glyco_hydro_16 PF00722.21 GAM35183.1 - 0.0049 16.4 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PDZ_1 PF12812.7 GAM35184.1 - 1.1e-20 73.4 3.1 8.4e-15 54.6 0.0 4.3 5 0 0 5 5 5 2 PDZ-like domain Trypsin_2 PF13365.6 GAM35184.1 - 6e-20 72.7 0.0 1.1e-18 68.6 0.0 2.3 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 GAM35184.1 - 5.4e-12 45.4 0.0 0.004 17.0 0.0 3.8 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 GAM35184.1 - 4.7e-11 42.9 0.1 0.011 16.1 0.0 3.9 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 GAM35184.1 - 1.2e-06 28.7 0.2 0.16 12.3 0.0 3.8 4 1 1 5 5 5 2 PDZ domain Trypsin PF00089.26 GAM35184.1 - 0.00059 19.7 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 GAM35184.1 - 0.0015 18.4 0.1 2.3 8.2 0.0 4.1 4 0 0 4 4 4 1 Tricorn protease PDZ domain Mito_carr PF00153.27 GAM35185.1 - 3.3e-60 200.0 0.1 3.7e-20 71.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TauE PF01925.19 GAM35185.1 - 0.022 14.4 0.1 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE tRNA-synt_2d PF01409.20 GAM35186.1 - 3.2e-49 167.6 0.2 6.5e-26 91.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 GAM35186.1 - 2.6e-28 98.3 0.0 6.2e-28 97.1 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.19 GAM35187.1 - 1.6e-42 145.0 4.4 2.1e-42 144.6 4.4 1.2 1 0 0 1 1 1 1 GrpE Uds1 PF15456.6 GAM35188.1 - 2.3e-27 95.7 9.6 2.3e-27 95.7 9.6 2.2 2 0 0 2 2 2 1 Up-regulated During Septation HhH-GPD PF00730.25 GAM35188.1 - 0.1 13.0 0.2 0.21 12.0 0.2 1.5 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein Tropomyosin_1 PF12718.7 GAM35188.1 - 0.38 10.9 5.8 1.1 9.4 5.8 1.8 1 0 0 1 1 1 0 Tropomyosin like TMF_TATA_bd PF12325.8 GAM35188.1 - 0.51 10.6 4.5 2 8.7 4.5 2.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 GAM35188.1 - 0.92 9.8 5.9 3.8 7.8 4.4 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 GAM35188.1 - 2.3 8.8 6.9 0.82 10.2 2.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Calcipressin PF04847.12 GAM35189.1 - 2.3e-33 115.5 0.2 4.3e-33 114.6 0.0 1.5 2 0 0 2 2 2 1 Calcipressin ATE_C PF04377.15 GAM35190.1 - 1.6e-47 161.5 1.4 3.1e-47 160.6 1.4 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus Acetyltransf_6 PF13480.7 GAM35190.1 - 0.0012 19.0 0.5 0.0012 19.0 0.5 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain NUDIX PF00293.28 GAM35191.1 - 5.2e-18 65.4 0.2 6.2e-18 65.1 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain DUF745 PF05335.13 GAM35192.1 - 0.0098 15.6 4.2 0.011 15.4 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) AAA_23 PF13476.6 GAM35192.1 - 0.086 13.3 3.2 0.098 13.2 3.2 1.2 1 0 0 1 1 1 0 AAA domain DUF2207 PF09972.9 GAM35192.1 - 0.1 11.4 1.8 0.13 11.0 1.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cortex-I_coil PF09304.10 GAM35192.1 - 0.82 9.9 9.0 0.36 11.1 6.4 1.8 2 1 0 2 2 2 0 Cortexillin I, coiled coil DUF1043 PF06295.12 GAM35192.1 - 1.1 9.3 8.4 2.2 8.3 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Exonuc_VII_L PF02601.15 GAM35192.1 - 1.2 8.7 5.9 1.4 8.4 5.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SlyX PF04102.12 GAM35192.1 - 3.1 8.5 13.3 4.4 8.0 10.3 2.3 1 1 1 2 2 2 0 SlyX SseC PF04888.12 GAM35192.1 - 5.9 6.4 7.9 7.7 6.0 7.9 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family GFO_IDH_MocA PF01408.22 GAM35193.1 - 2e-19 70.6 0.0 3.7e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 GAM35193.1 - 0.014 15.8 0.0 0.03 14.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NADH-G_4Fe-4S_3 PF10588.9 GAM35193.1 - 0.037 13.6 0.1 0.068 12.7 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF4930 PF16284.5 GAM35193.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4930) GST_N PF02798.20 GAM35194.1 - 2.3e-15 56.7 0.0 3.6e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAM35194.1 - 2.5e-12 47.0 0.0 4.1e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM35194.1 - 1.8e-09 37.7 0.0 3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM35194.1 - 8e-08 32.5 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM35194.1 - 9.6e-08 32.0 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM35194.1 - 0.00018 21.7 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RNA_pol_A_bac PF01000.26 GAM35195.1 - 7.9e-19 68.1 0.0 2.8e-16 59.9 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GAM35195.1 - 4.7e-17 61.2 0.0 6.2e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Baculo_PEP_C PF04513.12 GAM35196.1 - 0.0028 17.7 5.9 0.11 12.5 0.1 3.3 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 GAM35196.1 - 0.12 12.4 1.2 0.74 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 GAM35196.1 - 0.12 12.4 0.7 0.4 10.7 0.3 2.0 2 0 0 2 2 2 0 Laminin Domain II Cytochrom_C PF00034.21 GAM35197.1 - 4.3e-12 47.0 0.0 5.7e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 GAM35197.1 - 1.4e-08 35.0 1.7 5.8e-08 32.9 1.7 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 GAM35197.1 - 0.00017 21.3 0.5 0.0006 19.5 0.4 2.0 1 1 0 1 1 1 1 Cytochrome c-550 domain SVIP PF15811.5 GAM35198.1 - 6.8 7.2 7.1 0.25 11.8 0.7 1.9 3 0 0 3 3 3 0 Small VCP/p97-interacting protein RNase_PH PF01138.21 GAM35199.1 - 7.6e-10 39.4 0.0 0.00091 19.7 0.0 2.5 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 Fungal_trans PF04082.18 GAM35200.1 - 6.7e-05 22.0 1.0 0.00012 21.2 0.2 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain CoA_transf_3 PF02515.17 GAM35201.1 - 7.5e-44 150.3 0.0 3.8e-34 118.4 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III P53_C PF11619.8 GAM35201.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain MFS_1 PF07690.16 GAM35202.1 - 9.6e-29 100.4 30.2 2.2e-14 53.2 18.4 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily CoA_transf_3 PF02515.17 GAM35203.1 - 7.4e-44 150.4 0.0 3.8e-39 134.9 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III Pkinase PF00069.25 GAM35204.1 - 6.9e-59 199.4 0.0 1e-58 198.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM35204.1 - 2.1e-33 115.7 0.0 5.8e-32 111.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAM35204.1 - 0.0022 17.0 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 GAM35204.1 - 0.014 14.4 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stc1 PF12898.7 GAM35205.1 - 4.1e-17 62.5 6.9 7.5e-17 61.7 6.9 1.5 1 0 0 1 1 1 1 Stc1 domain Stn1 PF10451.9 GAM35207.1 - 3.3e-14 52.5 0.5 1.6e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 Telomere regulation protein Stn1 DUF5357 PF17310.2 GAM35207.1 - 0.48 8.9 2.6 0.72 8.4 2.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) Inv-AAD PF18785.1 GAM35208.1 - 6e-43 145.8 0.0 9e-43 145.2 0.0 1.2 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 GAM35208.1 - 5.9e-11 42.2 0.0 3.4e-10 39.7 0.0 2.2 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 GAM35208.1 - 1.2e-05 25.3 0.0 1.4e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain DnaJ PF00226.31 GAM35209.1 - 2.7e-23 81.9 5.6 2.7e-23 81.9 5.6 2.5 2 1 0 2 2 2 1 DnaJ domain RPT PF13446.6 GAM35209.1 - 0.018 15.0 0.0 0.058 13.3 0.0 1.8 1 0 0 1 1 1 0 A repeated domain in UCH-protein AA_permease_2 PF13520.6 GAM35210.1 - 8.4e-65 219.3 37.4 1.1e-64 218.9 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM35210.1 - 4.9e-15 55.1 37.2 7.6e-15 54.5 37.2 1.3 1 1 0 1 1 1 1 Amino acid permease Acetyltransf_13 PF13880.6 GAM35210.1 - 0.011 15.6 0.0 0.56 10.2 0.0 2.7 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase GMC_oxred_N PF00732.19 GAM35211.1 - 6.8e-47 160.3 0.0 8.7e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM35211.1 - 3.4e-30 105.5 0.0 5.7e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAM35211.1 - 8e-05 21.9 0.5 0.00014 21.1 0.5 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAM35211.1 - 0.0021 17.2 0.3 0.17 10.9 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 GAM35211.1 - 0.0023 17.2 0.2 0.0052 16.1 0.2 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 GAM35211.1 - 0.017 15.3 0.2 0.042 14.1 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM35211.1 - 0.025 14.2 0.2 0.061 12.9 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM35211.1 - 0.051 12.3 0.1 0.14 10.8 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 GAM35211.1 - 0.11 11.7 0.1 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1996 PF09362.10 GAM35212.1 - 2.5e-55 188.1 0.3 3.4e-55 187.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) p450 PF00067.22 GAM35213.1 - 1.6e-55 188.7 0.3 2.1e-55 188.3 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF829 PF05705.14 GAM35214.1 - 4.7e-41 141.3 0.0 5.7e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Fungal_trans_2 PF11951.8 GAM35215.1 - 0.0037 16.1 0.2 0.13 11.1 0.0 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Capsule_synth PF05159.14 GAM35215.1 - 0.055 12.9 0.0 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Capsule polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 GAM35216.1 - 1.9e-20 73.2 0.6 3.3e-20 72.4 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM35216.1 - 5e-07 30.8 0.1 1.3e-06 29.5 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAM35216.1 - 0.06 12.6 0.6 0.11 11.7 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_syntA PF00290.20 GAM35217.1 - 7.2e-93 310.2 0.0 1.3e-92 309.3 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 GAM35217.1 - 3.8e-49 167.7 2.3 8.7e-49 166.5 1.2 1.9 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Peripla_BP_6 PF13458.6 GAM35217.1 - 0.0072 16.0 0.0 0.031 13.9 0.0 2.1 2 1 0 2 2 2 1 Periplasmic binding protein ATP-synt_ab PF00006.25 GAM35218.1 - 3.2e-68 229.6 0.0 5e-68 228.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GAM35218.1 - 1.5e-13 51.0 0.2 3e-13 50.1 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Usp PF00582.26 GAM35219.1 - 5e-20 72.5 3.8 8.9e-13 49.0 0.2 3.5 3 0 0 3 3 3 3 Universal stress protein family p450 PF00067.22 GAM35220.1 - 2e-53 181.8 0.0 2.6e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GLEYA PF10528.9 GAM35221.1 - 2.7e-14 53.4 1.3 5e-14 52.5 1.3 1.5 1 0 0 1 1 1 1 GLEYA domain FMN_red PF03358.15 GAM35221.1 - 3.6e-06 26.8 0.0 5.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 GAM35221.1 - 0.12 12.6 0.1 0.51 10.5 0.1 2.1 1 1 0 1 1 1 0 Flavodoxin Amidohydro_2 PF04909.14 GAM35222.1 - 6.2e-32 111.5 0.1 7.6e-32 111.2 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase FAD_binding_3 PF01494.19 GAM35223.1 - 1.7e-48 165.7 0.0 2.6e-47 161.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAM35223.1 - 3.8e-11 43.3 0.0 6.9e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain OPT PF03169.15 GAM35224.1 - 4.7e-81 273.3 23.1 5.2e-81 273.1 23.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Fungal_trans PF04082.18 GAM35225.1 - 1e-14 54.2 2.6 1.5e-07 30.8 0.6 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Sulfatase PF00884.23 GAM35226.1 - 2e-63 214.6 0.0 2.5e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 GAM35226.1 - 0.038 13.6 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 GAM35226.1 - 0.13 13.0 0.1 1.4 9.6 0.1 2.6 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Sugar_tr PF00083.24 GAM35227.1 - 4.4e-86 289.5 25.8 5.6e-86 289.2 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM35227.1 - 6.3e-25 87.8 35.8 9.7e-23 80.6 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tmemb_55A PF09788.9 GAM35227.1 - 0.39 9.8 0.8 0.97 8.5 0.8 1.6 1 0 0 1 1 1 0 Transmembrane protein 55A DUF4022 PF13214.6 GAM35227.1 - 0.79 10.0 9.5 1.6 9.0 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4022) UbiA PF01040.18 GAM35228.1 - 8.2e-24 84.3 4.1 8.2e-24 84.3 4.1 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family Kinesin PF00225.23 GAM35229.1 - 4.9e-54 183.5 0.0 2.1e-31 109.1 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 GAM35229.1 - 6.1e-13 48.9 0.0 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding DUF4600 PF15372.6 GAM35229.1 - 0.16 12.4 0.6 2 8.9 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) TPR_12 PF13424.6 GAM35230.1 - 1.6e-27 95.6 13.1 8.1e-08 32.4 0.9 5.7 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 GAM35230.1 - 5.4e-16 57.9 20.3 0.0014 18.4 0.1 8.9 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAM35230.1 - 2.1e-08 33.7 12.2 0.017 15.2 0.1 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM35230.1 - 1.1e-05 25.9 8.7 2 9.5 0.0 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM35230.1 - 8e-05 22.6 10.6 0.065 13.5 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM35230.1 - 0.00041 20.8 4.9 0.008 16.7 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM35230.1 - 0.00088 19.8 1.9 0.26 12.0 0.1 3.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM35230.1 - 0.0011 18.7 10.6 0.18 11.7 0.1 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_3 PF07720.12 GAM35230.1 - 0.0086 16.1 0.2 0.064 13.3 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM35230.1 - 0.01 15.8 19.0 1.5 9.0 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAM35230.1 - 0.16 12.6 3.2 2.7 8.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM35230.1 - 1.6 9.0 6.4 3.3 8.0 0.4 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA PF00004.29 GAM35232.1 - 4.2e-32 111.3 0.0 9.7e-32 110.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM35232.1 - 8.5e-09 35.1 0.0 2.2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAM35232.1 - 9.7e-05 22.4 0.0 0.0005 20.1 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 GAM35232.1 - 0.00011 22.4 0.0 0.00035 20.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM35232.1 - 0.00012 22.5 1.1 0.015 15.7 0.1 3.2 1 1 2 3 3 3 1 AAA ATPase domain Vps4_C PF09336.10 GAM35232.1 - 0.00019 21.4 0.1 0.00078 19.4 0.0 2.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Hydin_ADK PF17213.3 GAM35232.1 - 0.00036 20.9 6.0 0.19 12.0 0.1 3.2 3 0 0 3 3 3 2 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 GAM35232.1 - 0.00069 19.9 0.2 0.3 11.3 0.1 3.2 3 1 0 3 3 1 1 AAA domain RuvB_N PF05496.12 GAM35232.1 - 0.0029 17.4 0.0 0.0061 16.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 GAM35232.1 - 0.0041 17.0 0.0 0.012 15.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 GAM35232.1 - 0.0049 16.6 0.0 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.17 GAM35232.1 - 0.0065 16.5 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 GAM35232.1 - 0.012 14.9 0.2 0.47 9.6 0.1 2.5 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_18 PF13238.6 GAM35232.1 - 0.024 15.2 0.0 0.084 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 GAM35232.1 - 0.037 14.1 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IPT PF01745.16 GAM35232.1 - 0.045 13.1 0.1 0.082 12.3 0.1 1.3 1 0 0 1 1 1 0 Isopentenyl transferase Uds1 PF15456.6 GAM35232.1 - 0.049 13.8 0.8 0.13 12.4 0.8 1.7 1 0 0 1 1 1 0 Up-regulated During Septation Bac_DnaA PF00308.18 GAM35232.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein RNA_helicase PF00910.22 GAM35232.1 - 0.086 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 GAM35232.1 - 0.14 11.9 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAM35232.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Parvo_NS1 PF01057.17 GAM35232.1 - 0.15 11.2 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 GAM35232.1 - 0.18 11.6 7.2 0.29 10.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAM35232.1 - 0.23 10.7 0.9 0.66 9.2 0.1 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_13 PF13166.6 GAM35232.1 - 0.44 9.1 2.2 0.39 9.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain GFO_IDH_MocA PF01408.22 GAM35233.1 - 1e-11 45.7 0.0 3.3e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF1010 PF06231.11 GAM35233.1 - 0.11 13.0 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) Sugar_tr PF00083.24 GAM35234.1 - 1.3e-97 327.5 27.0 1.7e-97 327.2 27.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM35234.1 - 6.6e-19 68.0 65.1 2.3e-18 66.2 36.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_N PF02798.20 GAM35235.1 - 6.7e-09 36.0 0.1 1.5e-08 34.8 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAM35235.1 - 2.2e-08 34.4 0.0 8.5e-07 29.3 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM35235.1 - 1.3e-06 28.6 0.1 3.4e-06 27.3 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain BTB_2 PF02214.22 GAM35235.1 - 2.7e-05 24.4 0.3 0.0006 20.1 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain GST_C PF00043.25 GAM35235.1 - 0.026 14.7 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NDUF_B4 PF07225.12 GAM35236.1 - 2.3e-06 27.5 0.0 2.5e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) EamA PF00892.20 GAM35236.1 - 0.0045 17.1 0.1 0.0052 17.0 0.1 1.1 1 0 0 1 1 1 1 EamA-like transporter family SAP18 PF06487.12 GAM35237.1 - 5.3e-48 162.7 0.0 6.3e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.15 GAM35238.1 - 6.2e-56 188.4 0.0 6.2e-56 188.4 0.0 2.1 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 GAM35238.1 - 3.2e-13 49.0 0.5 3.2e-13 49.0 0.5 2.9 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like V_ATPase_I PF01496.19 GAM35238.1 - 3.1 5.6 4.3 3.9 5.3 4.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_16 PF13191.6 GAM35239.1 - 1e-05 26.0 0.0 1e-05 26.0 0.0 3.6 4 1 0 4 4 4 1 AAA ATPase domain NACHT PF05729.12 GAM35239.1 - 1.1e-05 25.4 0.1 0.00032 20.7 0.0 3.0 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 GAM35239.1 - 3.1e-05 24.3 0.0 0.00024 21.4 0.0 2.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM35239.1 - 0.0024 17.6 0.0 0.01 15.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain Rep_1 PF01446.17 GAM35239.1 - 0.016 14.7 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Replication protein TPR_12 PF13424.6 GAM35239.1 - 0.04 14.2 12.8 3.5 8.0 0.2 6.8 6 1 0 6 6 6 0 Tetratricopeptide repeat ATPase PF06745.13 GAM35239.1 - 0.045 13.1 0.1 0.48 9.7 0.0 2.5 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.22 GAM35239.1 - 0.074 12.2 0.1 0.31 10.2 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain TPR_14 PF13428.6 GAM35239.1 - 2.7 9.1 6.2 54 5.0 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Glyco_hydro_71 PF03659.14 GAM35240.1 - 1.6e-91 306.9 2.3 2.4e-91 306.3 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_31 PF01055.26 GAM35241.1 - 6.3e-103 345.3 4.5 9.1e-103 344.8 4.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Zn_clus PF00172.18 GAM35241.1 - 7.3e-07 29.2 8.9 1.2e-06 28.5 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM35241.1 - 7.1e-05 22.0 1.7 0.00016 20.8 1.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF5110 PF17137.4 GAM35241.1 - 0.00087 19.5 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 GAM35241.1 - 0.026 14.8 0.0 0.068 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) Glyco_hyd_65N_2 PF14498.6 GAM35242.1 - 5.8e-52 176.9 0.1 8.2e-52 176.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Sugar_tr PF00083.24 GAM35243.1 - 6.6e-77 259.3 24.7 8.2e-77 259.0 24.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM35243.1 - 3.8e-18 65.6 38.9 1.4e-17 63.6 22.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MNHE PF01899.16 GAM35243.1 - 9.6 6.0 11.7 0.17 11.6 2.2 2.5 2 1 1 3 3 3 0 Na+/H+ ion antiporter subunit Zn_clus PF00172.18 GAM35244.1 - 6.3e-08 32.6 13.8 1e-07 32.0 13.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM35244.1 - 2.7e-07 29.9 0.2 4.2e-07 29.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lipase_GDSL_2 PF13472.6 GAM35245.1 - 5.4e-23 82.3 0.1 6.7e-23 82.0 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAM35245.1 - 1.9e-16 60.7 0.0 3.2e-16 59.9 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Raffinose_syn PF05691.12 GAM35246.1 - 6.3e-30 103.6 0.3 7.6e-22 76.9 0.0 3.1 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Melibiase_2 PF16499.5 GAM35247.1 - 4.8e-14 52.2 1.7 4.6e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 GAM35247.1 - 4.4e-08 33.1 0.1 1.3e-07 31.6 0.1 1.8 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain TPP_enzyme_N PF02776.18 GAM35247.1 - 0.16 11.6 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain NAD_binding_10 PF13460.6 GAM35248.1 - 4.4e-05 23.4 0.0 5.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM35248.1 - 0.0049 16.3 0.0 0.087 12.3 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM35248.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 GAM35248.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 GAM35248.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Semialdhyde_dh PF01118.24 GAM35248.1 - 0.18 12.2 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 GAM35249.1 - 1.9e-31 109.0 0.0 4e-31 108.0 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35249.1 - 4.1e-19 69.1 0.0 9.1e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAD_binding_4 PF01565.23 GAM35249.1 - 9.8e-13 48.0 0.4 2.5e-12 46.7 0.4 1.7 1 0 0 1 1 1 1 FAD binding domain KR PF08659.10 GAM35249.1 - 1.9e-07 31.2 0.1 5.1e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAM35249.1 - 0.00094 18.7 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.24 GAM35250.1 - 1.8e-82 277.6 22.0 2.1e-82 277.4 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM35250.1 - 1e-17 64.1 27.9 1e-17 64.1 27.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 GAM35250.1 - 2.6e-08 32.9 20.8 1e-05 24.3 2.5 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein ABC_tran PF00005.27 GAM35251.1 - 5.5e-43 146.8 0.0 4.1e-23 82.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAM35251.1 - 1.1e-39 136.7 21.6 5.2e-24 85.3 11.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GAM35251.1 - 2e-08 34.0 0.2 0.08 12.4 0.1 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 GAM35251.1 - 8.7e-05 22.2 0.0 0.03 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM35251.1 - 0.0001 22.8 0.1 0.013 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 GAM35251.1 - 0.00018 22.1 0.7 0.0009 19.8 0.1 2.1 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAM35251.1 - 0.00037 19.6 1.0 0.0094 15.0 0.6 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 GAM35251.1 - 0.00038 20.1 1.1 0.078 12.7 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 GAM35251.1 - 0.0023 18.2 0.6 0.25 11.6 0.1 3.4 3 0 0 3 3 3 1 AAA domain Phage_holin_2_3 PF16080.5 GAM35251.1 - 0.0063 16.2 0.1 0.021 14.5 0.1 2.0 1 0 0 1 1 1 1 Bacteriophage holin family HP1 AAA_30 PF13604.6 GAM35251.1 - 0.022 14.5 0.3 0.95 9.1 0.1 2.7 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 GAM35251.1 - 0.023 15.1 0.9 7.9 6.9 0.1 3.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 GAM35251.1 - 0.025 14.6 0.5 0.056 13.5 0.0 1.8 2 0 0 2 2 2 0 Dynamin family AAA_21 PF13304.6 GAM35251.1 - 0.028 14.2 8.0 0.2 11.5 0.7 3.3 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 GAM35251.1 - 0.043 13.4 0.4 0.043 13.4 0.4 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 GAM35251.1 - 0.078 12.7 0.1 0.39 10.4 0.0 2.1 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 GAM35251.1 - 0.079 12.1 0.1 12 5.0 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain pPIWI_RE_REase PF18154.1 GAM35251.1 - 0.092 12.7 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 1 0 REase associating with pPIWI_RE Pox_A32 PF04665.12 GAM35251.1 - 0.097 12.1 2.1 1.1 8.7 0.3 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein MMR_HSR1 PF01926.23 GAM35251.1 - 0.12 12.5 0.6 8.7 6.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM35251.1 - 0.12 12.3 1.0 0.33 10.8 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 GAM35251.1 - 0.22 11.3 0.1 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAM35251.1 - 0.22 11.4 2.5 2.7 7.9 0.4 2.7 3 0 0 3 3 2 0 NTPase AAA_5 PF07728.14 GAM35251.1 - 0.29 11.1 1.6 29 4.6 0.0 3.7 4 1 0 4 4 4 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 GAM35251.1 - 0.35 10.7 1.5 0.72 9.7 0.0 2.2 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 GAM35251.1 - 0.53 10.2 2.6 1 9.2 0.0 2.6 3 0 0 3 3 2 0 NACHT domain DUF87 PF01935.17 GAM35251.1 - 0.63 10.1 3.8 8.1 6.5 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Amidohydro_3 PF07969.11 GAM35252.1 - 5.3e-17 62.4 0.2 4.4e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 GAM35252.1 - 9.1e-15 54.8 0.4 2.5e-13 50.1 0.1 2.8 2 1 0 2 2 2 1 Amidohydrolase family Peptidase_M20 PF01546.28 GAM35253.1 - 2e-26 93.0 0.0 8e-26 91.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM35253.1 - 1.3e-09 38.0 0.0 2.9e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.8 GAM35254.1 - 0.0024 16.7 4.1 0.01 14.7 0.2 2.4 3 0 0 3 3 3 2 Fungal specific transcription factor domain MFS_1 PF07690.16 GAM35255.1 - 1.8e-11 43.6 7.4 3.4e-08 32.8 3.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CDI PF02234.19 GAM35255.1 - 0.0033 17.6 0.3 0.027 14.6 0.0 2.3 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor Sugar_tr PF00083.24 GAM35255.1 - 0.0043 16.0 0.2 0.007 15.3 0.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4131 PF13567.6 GAM35255.1 - 0.076 12.7 1.5 0.26 10.9 1.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3587 PF12132.8 GAM35255.1 - 0.2 11.1 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3587) ESSS PF10183.9 GAM35255.1 - 0.21 11.8 1.3 0.76 10.0 0.2 2.4 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF308 PF03729.13 GAM35255.1 - 1.2 9.5 6.5 2.4 8.5 5.4 2.0 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Pyr_redox_3 PF13738.6 GAM35256.1 - 0.27 10.4 0.0 0.43 9.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Arf PF00025.21 GAM35257.1 - 4.6e-40 136.9 0.1 7.1e-27 94.0 0.1 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 GAM35257.1 - 1.6e-14 53.9 0.0 1.1e-08 34.7 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 GAM35257.1 - 4.5e-12 46.2 0.0 1.1e-11 44.9 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAM35257.1 - 9.3e-10 38.2 0.0 1.2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 GAM35257.1 - 2.4e-08 33.7 0.0 3.8e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Ras family SRPRB PF09439.10 GAM35257.1 - 1.8e-06 27.5 0.0 9.3e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAM35257.1 - 2.2e-05 24.5 0.0 3.7e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM35257.1 - 0.00081 19.0 1.0 0.0094 15.5 1.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 GAM35257.1 - 0.074 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 GAM35257.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PIGA PF08288.12 GAM35259.1 - 2.4e-45 153.1 2.1 3.6e-45 152.5 1.0 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 GAM35259.1 - 1.5e-28 99.5 0.0 2.3e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAM35259.1 - 1.6e-28 99.9 0.3 2.7e-28 99.1 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 GAM35259.1 - 1.7e-24 86.8 0.1 3.1e-24 85.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAM35259.1 - 1.1e-11 45.5 0.0 1.9e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 GAM35259.1 - 1.4e-05 25.2 0.1 3e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 GAM35259.1 - 0.00038 20.8 0.0 0.00096 19.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 DEAD PF00270.29 GAM35260.1 - 1.1e-36 126.3 0.0 5.6e-19 68.6 0.0 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM35260.1 - 1.3e-19 70.6 0.2 9.5e-19 67.8 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM35260.1 - 8.2e-10 38.9 0.1 5.4e-09 36.3 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAM35260.1 - 0.00013 22.3 0.0 0.0008 19.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAM35260.1 - 0.052 13.8 0.1 14 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AMP-binding PF00501.28 GAM35261.1 - 2.3e-27 95.7 0.0 9.2e-25 87.1 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme RELT PF12606.8 GAM35261.1 - 0.19 10.7 0.2 0.37 9.8 0.2 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 GMC_oxred_N PF00732.19 GAM35263.1 - 2.3e-49 168.4 1.1 3.5e-49 167.8 1.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM35263.1 - 1.3e-29 103.5 0.1 4e-29 102.0 0.1 1.8 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 GAM35263.1 - 9e-06 25.1 1.6 3.7e-05 23.1 0.6 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM35263.1 - 1.4e-05 24.4 6.2 7.5e-05 22.0 6.2 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAM35263.1 - 9.5e-05 21.8 0.1 0.00021 20.7 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM35263.1 - 0.00047 20.3 1.4 0.0012 19.0 0.3 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAM35263.1 - 0.00089 18.6 0.2 0.0018 17.6 0.2 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 GAM35263.1 - 0.0037 16.7 3.3 0.0064 15.9 1.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 GAM35263.1 - 0.027 14.1 5.8 0.17 11.5 5.8 2.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM35263.1 - 0.028 13.1 1.5 0.037 12.7 0.5 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 GAM35263.1 - 0.047 12.9 0.0 7.5 5.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM35263.1 - 0.074 12.1 0.3 0.18 10.8 0.2 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 GAM35263.1 - 0.16 12.6 0.1 0.32 11.6 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_1 PF00583.25 GAM35265.1 - 1e-06 28.9 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 GAM35265.1 - 1.8e-05 25.3 0.0 2.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM35265.1 - 2.6e-05 24.2 0.1 0.12 12.3 0.0 2.8 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM35265.1 - 0.0009 19.6 0.0 0.0024 18.3 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM35265.1 - 0.011 15.8 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FYVE PF01363.21 GAM35266.1 - 9.5e-16 57.7 8.3 1.5e-15 57.1 8.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 GAM35266.1 - 0.02 15.1 9.0 0.02 15.1 9.0 2.0 2 0 0 2 2 2 0 AN1-like Zinc finger Transferase PF02458.15 GAM35267.1 - 7.4e-24 84.2 0.1 3.1e-23 82.1 0.1 2.0 1 1 0 1 1 1 1 Transferase family WES_acyltransf PF03007.16 GAM35267.1 - 0.094 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 GAM35267.1 - 0.1 11.2 0.1 0.36 9.4 0.0 1.8 2 0 0 2 2 2 0 Condensation domain Aldedh PF00171.22 GAM35268.1 - 7.9e-137 456.5 4.1 9.8e-137 456.2 4.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAM35268.1 - 0.00063 18.9 1.0 0.00078 18.6 0.2 1.6 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) TPP_enzyme_N PF02776.18 GAM35269.1 - 6.7e-32 110.5 0.4 7.8e-31 107.0 0.3 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAM35269.1 - 1.2e-22 80.3 0.1 1.2e-22 80.3 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAM35269.1 - 2.2e-12 46.9 0.0 1.2e-11 44.5 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain XFP_N PF09364.10 GAM35269.1 - 0.053 12.3 0.1 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 XFP N-terminal domain FAD_binding_3 PF01494.19 GAM35270.1 - 1.7e-13 50.6 0.0 2.4e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM35270.1 - 0.00021 21.0 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 GAM35270.1 - 0.0016 17.6 0.0 0.0042 16.2 0.0 1.6 1 1 0 1 1 1 1 Squalene epoxidase MFS_1 PF07690.16 GAM35271.1 - 4e-35 121.4 33.2 6.4e-35 120.7 33.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM35271.1 - 5.5e-14 51.9 7.8 5.5e-14 51.9 7.8 2.7 1 1 0 2 2 2 1 Sugar (and other) transporter Peptidase_A8 PF01252.18 GAM35271.1 - 2 8.6 10.0 0.43 10.8 1.5 3.3 3 0 0 3 3 3 0 Signal peptidase (SPase) II adh_short_C2 PF13561.6 GAM35272.1 - 1.9e-46 158.5 0.2 2.2e-46 158.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM35272.1 - 5.2e-37 127.2 0.2 6e-37 127.0 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM35272.1 - 9.1e-12 45.2 0.1 1.4e-11 44.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM35272.1 - 0.00064 19.3 0.1 0.00088 18.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM35272.1 - 0.0019 17.7 0.1 0.0038 16.7 0.1 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Dak1_2 PF13684.6 GAM35272.1 - 0.0072 15.4 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Dihydroxyacetone kinase family Peptidase_S64 PF08192.11 GAM35273.1 - 0.063 11.8 0.2 1.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S64 MARVEL PF01284.23 GAM35274.1 - 0.022 14.8 14.9 0.15 12.0 14.8 2.0 1 1 1 2 2 2 0 Membrane-associating domain RTA1 PF04479.13 GAM35275.1 - 3.4e-53 180.3 5.2 4.8e-53 179.9 5.2 1.2 1 0 0 1 1 1 1 RTA1 like protein Sugar_tr PF00083.24 GAM35276.1 - 8.3e-39 133.7 25.0 1.4e-25 90.0 6.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM35276.1 - 4.6e-24 85.0 26.7 4.6e-24 85.0 26.7 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 GAM35277.1 - 6.7e-44 149.7 0.4 8.4e-44 149.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35277.1 - 5.4e-38 130.8 0.4 9.4e-38 130.1 0.4 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM35277.1 - 4.2e-15 56.1 0.1 5.6e-15 55.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 GAM35277.1 - 0.00048 19.8 1.5 0.0022 17.7 0.7 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.15 GAM35277.1 - 0.0027 16.9 0.3 0.0035 16.5 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAM35277.1 - 0.0085 15.6 0.1 0.035 13.5 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIG_1_N PF04588.13 GAM35278.1 - 0.0096 16.1 0.1 0.023 14.9 0.1 1.6 2 0 0 2 2 2 1 Hypoxia induced protein conserved region FeoB_associated PF12669.7 GAM35278.1 - 0.061 13.7 0.3 0.097 13.1 0.3 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein UPF0697 PF15117.6 GAM35278.1 - 0.18 11.9 0.4 0.36 10.9 0.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0697 Presenilin PF01080.17 GAM35279.1 - 0.001 18.0 7.9 0.0012 17.7 7.9 1.2 1 0 0 1 1 1 1 Presenilin Neur_chan_memb PF02932.16 GAM35279.1 - 0.0029 17.7 5.8 0.0044 17.1 5.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 GAM35279.1 - 0.012 14.0 1.3 0.016 13.6 1.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HemX PF04375.14 GAM35279.1 - 0.013 14.8 7.6 0.019 14.2 7.6 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Zip PF02535.22 GAM35279.1 - 0.017 14.3 1.1 0.017 14.4 1.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4778 PF16008.5 GAM35279.1 - 0.018 15.1 14.3 0.023 14.8 14.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) V_ATPase_I PF01496.19 GAM35279.1 - 0.025 12.5 7.0 0.037 12.0 7.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rrn6 PF10214.9 GAM35279.1 - 0.048 12.2 6.8 0.051 12.1 6.8 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor UPF0242 PF06785.11 GAM35279.1 - 0.16 12.1 16.0 0.26 11.4 16.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DDHD PF02862.17 GAM35279.1 - 0.35 11.0 4.5 0.47 10.6 4.5 1.3 1 0 0 1 1 1 0 DDHD domain PA26 PF04636.13 GAM35279.1 - 0.39 9.6 8.6 0.48 9.3 8.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SLC12 PF03522.15 GAM35279.1 - 1 8.3 10.3 1.3 8.0 10.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Borrelia_P83 PF05262.11 GAM35279.1 - 1.8 6.9 14.5 1.9 6.9 14.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_11 PF13086.6 GAM35279.1 - 8.8 6.0 16.4 14 5.4 16.4 1.4 1 0 0 1 1 1 0 AAA domain ALMT PF11744.8 GAM35279.1 - 9.8 4.9 10.5 14 4.4 10.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DIOX_N PF14226.6 GAM35280.1 - 6.9e-24 84.9 0.0 1.2e-23 84.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM35280.1 - 8.6e-17 61.5 0.0 1.8e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CARD PF00619.21 GAM35280.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Caspase recruitment domain Methyltr_RsmB-F PF01189.17 GAM35281.1 - 5.1e-15 55.6 0.0 4.2e-08 33.1 0.0 2.7 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F DUF520 PF04461.13 GAM35281.1 - 0.1 12.7 0.1 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF520) TPP_enzyme_N PF02776.18 GAM35282.1 - 1e-45 155.4 0.8 2.8e-45 154.0 0.8 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAM35282.1 - 1.1e-38 132.4 0.1 2.2e-37 128.2 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAM35282.1 - 8.3e-24 83.9 0.0 1.7e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain AAL_decarboxy PF03306.13 GAM35283.1 - 1.1e-37 129.5 0.0 1.2e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase Mtc PF03820.17 GAM35284.1 - 4.7e-118 393.8 0.0 5.2e-118 393.6 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.25 GAM35285.1 - 4e-51 173.9 0.1 1.6e-50 172.0 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM35285.1 - 1.2e-20 74.0 0.1 2e-19 69.9 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase TAF4 PF05236.14 GAM35286.1 - 1.1e-31 110.6 0.5 1.7e-30 106.7 0.5 2.2 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 GAM35287.1 - 2.7e-77 259.2 0.3 3.8e-77 258.7 0.3 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 GAM35287.1 - 2e-29 102.1 0.0 4.9e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 GAM35287.1 - 3.2e-21 76.3 0.2 5.8e-21 75.4 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 GAM35287.1 - 3.5e-15 55.9 0.1 5.8e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 GAM35287.1 - 1.1e-12 47.7 0.2 4.1e-12 45.8 0.0 2.1 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 GAM35287.1 - 0.00049 20.0 0.1 0.0015 18.5 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 GAM35287.1 - 0.00051 19.6 0.1 0.001 18.6 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lyase_aromatic PF00221.19 GAM35288.1 - 4.4e-148 493.8 0.7 5.7e-148 493.4 0.7 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Aminotran_1_2 PF00155.21 GAM35289.1 - 3.5e-41 141.6 0.0 5e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3328 PF11807.8 GAM35289.1 - 8.3e-21 74.8 2.5 1.2e-20 74.2 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Aminotran_5 PF00266.19 GAM35289.1 - 0.02 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAM35289.1 - 0.089 12.1 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 GAM35289.1 - 0.098 11.2 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme AMP-binding PF00501.28 GAM35290.1 - 0 1078.6 0.0 3.8e-75 253.1 0.0 6.1 5 1 1 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 GAM35290.1 - 2.1e-172 573.9 0.1 4.6e-40 137.6 0.1 5.6 5 1 0 5 5 5 5 Condensation domain PP-binding PF00550.25 GAM35290.1 - 4.8e-54 180.6 3.9 1.2e-11 44.8 0.0 6.5 6 0 0 6 6 6 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAM35290.1 - 1.6e-11 45.0 0.0 0.0025 18.8 0.0 5.6 5 0 0 5 5 5 2 AMP-binding enzyme C-terminal domain ABC_tran PF00005.27 GAM35291.1 - 1.5e-50 171.3 0.0 5.6e-31 107.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAM35291.1 - 2.7e-44 151.9 19.9 1.4e-27 97.1 9.4 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region RsgA_GTPase PF03193.16 GAM35291.1 - 5e-08 33.0 0.0 0.00072 19.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 GAM35291.1 - 2.2e-07 31.6 0.1 0.0021 18.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 GAM35291.1 - 1e-06 28.8 0.9 0.095 12.5 0.1 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM35291.1 - 1.2e-06 28.1 0.3 0.13 11.7 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM35291.1 - 4.8e-06 26.2 0.0 0.066 13.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAM35291.1 - 3.4e-05 23.9 0.1 0.024 14.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAM35291.1 - 5.8e-05 23.5 0.6 0.24 11.8 0.5 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAM35291.1 - 8.5e-05 22.9 0.3 0.79 10.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 GAM35291.1 - 0.00053 19.8 0.0 0.028 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAM35291.1 - 0.00054 19.6 0.0 0.75 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 GAM35291.1 - 0.0008 18.5 0.0 0.79 8.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Methyltransf_12 PF08242.12 GAM35291.1 - 0.0012 19.5 0.3 0.089 13.5 0.0 2.9 1 1 1 2 2 2 1 Methyltransferase domain Adeno_IVa2 PF02456.15 GAM35291.1 - 0.0046 15.8 0.0 1.5 7.6 0.0 2.5 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_33 PF13671.6 GAM35291.1 - 0.0052 17.0 0.1 0.95 9.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 GAM35291.1 - 0.0081 16.2 0.3 0.35 10.9 0.1 2.4 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.6 GAM35291.1 - 0.0086 16.6 0.0 6.8 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 GAM35291.1 - 0.0089 15.0 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 GAM35291.1 - 0.015 15.1 0.1 0.094 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 GAM35291.1 - 0.018 15.2 0.1 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 GAM35291.1 - 0.02 14.7 0.1 10 5.8 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein cobW PF02492.19 GAM35291.1 - 0.029 13.9 0.5 7.1 6.2 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 GAM35291.1 - 0.03 13.5 0.0 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 GAM35291.1 - 0.036 13.3 0.0 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 GAM35291.1 - 0.073 13.5 0.0 17 5.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 GAM35291.1 - 0.074 12.8 0.1 8.5 6.0 0.1 2.6 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 GAM35291.1 - 0.075 12.9 0.9 4.5 7.2 0.1 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 GAM35291.1 - 0.11 11.9 0.0 14 4.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF4387 PF14330.6 GAM35293.1 - 1.5e-33 115.3 0.0 3.1e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 GAM35293.1 - 4.8e-12 45.3 0.0 7.9e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Aminotran_3 PF00202.21 GAM35294.1 - 1.6e-92 310.3 0.0 1.9e-92 310.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SRP19 PF01922.17 GAM35295.1 - 2.1e-13 51.0 0.1 1.8e-12 48.0 0.0 2.1 1 1 1 2 2 2 1 SRP19 protein Rad60-SLD PF11976.8 GAM35295.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Fungal_trans PF04082.18 GAM35296.1 - 1.5e-13 50.4 0.1 1.5e-13 50.4 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM35296.1 - 2e-10 40.6 11.1 3.4e-10 39.9 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIP-T3_C PF17749.1 GAM35296.1 - 0.065 13.2 0.8 0.17 11.8 0.8 1.6 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region TCTP PF00838.17 GAM35297.1 - 1.7e-58 197.6 0.4 1.9e-58 197.4 0.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Cullin PF00888.22 GAM35297.1 - 0.0093 14.6 0.1 0.012 14.3 0.1 1.0 1 0 0 1 1 1 1 Cullin family DUF3627 PF12299.8 GAM35297.1 - 0.049 13.7 0.4 0.14 12.2 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3627) DUF3533 PF12051.8 GAM35298.1 - 3.8e-87 292.7 19.7 4.6e-87 292.4 19.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) VTC PF09359.10 GAM35298.1 - 0.27 10.6 1.1 0.39 10.1 1.1 1.1 1 0 0 1 1 1 0 VTC domain Zn_clus PF00172.18 GAM35299.1 - 2.6e-10 40.3 8.4 4.7e-10 39.4 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.10 GAM35299.1 - 8.7e-07 28.7 0.3 1.4e-06 28.0 0.3 1.4 1 0 0 1 1 1 1 Aflatoxin regulatory protein FA_hydroxylase PF04116.13 GAM35300.1 - 2.8e-24 86.0 13.9 2.8e-24 86.0 13.9 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2293 PF10056.9 GAM35301.1 - 7.7e-28 96.6 0.3 1.8e-27 95.4 0.3 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) APC_u5 PF16630.5 GAM35302.1 - 2.3 9.3 8.6 5.8 8.0 0.4 2.9 2 0 0 2 2 2 0 Unstructured region on APC between 1st and 2nd catenin-bdg motifs GST_C PF00043.25 GAM35303.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Chorion_2 PF03964.15 GAM35303.1 - 3 8.7 6.4 5.7 7.8 6.4 1.5 1 1 0 1 1 1 0 Chorion family 2 TruD PF01142.18 GAM35304.1 - 1.4e-66 225.1 0.1 7.9e-62 209.4 0.1 3.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Spt20 PF12090.8 GAM35305.1 - 1.2e-59 201.7 7.3 1.2e-59 201.7 7.3 6.2 3 2 1 4 4 4 1 Spt20 family Shadoo PF14999.6 GAM35306.1 - 3.8 7.6 9.6 5.2 7.2 7.6 2.3 2 1 0 2 2 2 0 Shadow of prion protein, neuroprotective Sulfotransfer_4 PF17784.1 GAM35307.1 - 8.4e-42 143.4 0.0 9.9e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain zf-C2H2 PF00096.26 GAM35308.1 - 6.4e-09 35.8 10.4 0.00041 20.6 3.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM35308.1 - 3.9e-05 23.9 2.9 3.9e-05 23.9 2.9 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAM35308.1 - 5e-05 23.8 6.5 0.0098 16.7 2.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 GAM35308.1 - 0.00057 20.5 3.6 0.35 11.5 0.2 2.5 1 1 1 2 2 2 2 FOXP coiled-coil domain Sina PF03145.16 GAM35308.1 - 0.079 12.9 1.5 0.12 12.3 1.5 1.2 1 0 0 1 1 1 0 Seven in absentia protein family zf-C2H2_6 PF13912.6 GAM35308.1 - 0.41 10.7 9.0 2.6 8.2 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger MFS_1 PF07690.16 GAM35309.1 - 3.5e-21 75.5 28.4 3.5e-21 75.5 28.4 2.5 1 1 1 3 3 3 2 Major Facilitator Superfamily Ribonuclease_T2 PF00445.18 GAM35310.1 - 7.6e-39 133.8 0.1 1.1e-38 133.3 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family BCNT PF07572.12 GAM35311.1 - 2.6e-26 91.5 0.5 6.5e-26 90.2 0.5 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development ECH_1 PF00378.20 GAM35312.1 - 1.1e-28 100.2 0.0 1.5e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM35312.1 - 2.6e-16 60.1 0.0 2.8e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Hexapep PF00132.24 GAM35313.1 - 1.3e-08 34.2 6.0 0.00048 19.8 1.1 2.8 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 GAM35313.1 - 4.4e-05 22.6 2.5 0.013 14.5 0.1 2.2 1 1 1 2 2 2 2 L-fucokinase DUF4954 PF16314.5 GAM35313.1 - 0.12 10.4 1.3 0.4 8.8 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 GAM35313.1 - 2.9 7.7 8.3 9.6 6.1 0.7 3.2 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Remorin_N PF03766.13 GAM35314.1 - 0.069 13.2 0.2 0.32 11.1 0.2 2.2 1 0 0 1 1 1 0 Remorin, N-terminal region ELO PF01151.18 GAM35315.1 - 4.1e-83 278.7 4.3 5e-83 278.5 4.3 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1275 PF06912.11 GAM35316.1 - 6.4e-43 146.9 8.8 7.4e-43 146.7 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) GPI2 PF06432.11 GAM35316.1 - 0.025 14.0 3.2 0.018 14.5 1.2 1.7 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4267 PF14087.6 GAM35316.1 - 0.14 12.2 2.7 6.3 6.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) DUF4131 PF13567.6 GAM35316.1 - 3.7 7.2 6.4 4.5 6.9 0.3 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) MFS_1 PF07690.16 GAM35317.1 - 6e-12 45.1 36.5 9.5e-08 31.3 12.3 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Bap31 PF05529.12 GAM35317.1 - 1.6 8.6 10.9 0.19 11.6 3.2 3.0 3 0 0 3 3 3 0 Bap31/Bap29 transmembrane region DIOX_N PF14226.6 GAM35318.1 - 1.3e-19 71.1 0.1 8.7e-10 39.4 0.0 2.3 1 1 1 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM35318.1 - 1.2e-11 45.0 0.0 2.4e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 GAM35319.1 - 9.3e-96 321.0 0.3 4.8e-53 180.3 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 GAM35319.1 - 3.1e-72 243.7 0.0 4.6e-39 134.4 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 GAM35319.1 - 8.3e-28 96.5 1.0 1.3e-12 47.8 0.0 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site Trypsin PF00089.26 GAM35319.1 - 0.098 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Trypsin AMP-binding PF00501.28 GAM35320.1 - 8.7e-143 475.9 0.0 2e-67 227.7 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 GAM35320.1 - 2.9e-83 280.1 0.0 1.9e-41 142.2 0.0 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 GAM35320.1 - 4.7e-17 62.1 0.3 3.3e-07 30.5 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAM35320.1 - 1.3e-06 29.2 0.3 0.012 16.6 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain GH3 PF03321.13 GAM35320.1 - 0.0064 15.4 0.1 0.2 10.4 0.0 2.5 3 0 0 3 3 3 1 GH3 auxin-responsive promoter Condensation PF00668.20 GAM35321.1 - 1.5e-30 106.3 0.0 2e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 GAM35321.1 - 5.9e-23 81.1 0.1 9.4e-23 80.5 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 GAM35321.1 - 3.3e-11 43.4 0.1 1.3e-10 41.5 0.0 2.1 1 1 1 2 2 2 1 Phosphopantetheine attachment site p450 PF00067.22 GAM35322.1 - 2.1e-38 132.3 0.0 2.8e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 GAM35323.1 - 6.1e-37 127.4 55.3 6.1e-37 127.4 55.3 3.0 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM35323.1 - 1.8e-06 26.7 26.2 2e-06 26.5 25.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 GAM35323.1 - 0.45 8.7 14.9 2.6 6.2 14.8 2.2 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 GAM35324.1 - 3.5e-36 124.9 40.4 3.5e-36 124.9 40.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.25 GAM35324.1 - 1.1e-24 87.0 0.0 2e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35324.1 - 2.7e-16 59.9 0.0 4.4e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sugar_tr PF00083.24 GAM35324.1 - 5.4e-11 42.0 3.8 5.4e-11 42.0 3.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAM35324.1 - 7.6e-08 31.2 3.9 1.2e-07 30.6 3.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Wzz PF02706.15 GAM35324.1 - 3.4 8.0 8.3 0.74 10.2 0.6 3.4 3 0 0 3 3 3 0 Chain length determinant protein p450 PF00067.22 GAM35325.1 - 2.4e-34 118.9 0.1 2.9e-34 118.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 GAM35326.1 - 8.4e-45 152.6 0.2 1.1e-44 152.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35326.1 - 1.9e-38 132.3 0.1 2.7e-37 128.6 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM35326.1 - 0.0015 18.5 0.4 0.0053 16.7 0.4 1.8 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 GAM35326.1 - 0.0016 18.2 1.0 0.016 14.9 0.4 2.4 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 GAM35326.1 - 0.076 12.5 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 GAM35327.1 - 5.8e-29 101.1 0.0 9.1e-25 87.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 adh_short PF00106.25 GAM35330.1 - 4.6e-30 104.5 0.0 6.5e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35330.1 - 8e-27 94.3 0.2 5.6e-26 91.5 0.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM35330.1 - 1.1e-06 28.7 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 KR domain p450 PF00067.22 GAM35331.1 - 2.9e-27 95.5 0.0 2.1e-26 92.7 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Sin3_corepress PF08295.12 GAM35331.1 - 0.2 11.7 0.0 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Sin3 family co-repressor p450 PF00067.22 GAM35332.1 - 6.5e-59 199.9 0.0 9.1e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 GAM35332.1 - 5e-24 84.9 0.0 7.8e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35332.1 - 7.5e-17 61.7 0.0 1.2e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 GAM35332.1 - 7.2e-05 22.3 0.0 0.00025 20.5 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) TrbH PF07283.11 GAM35332.1 - 0.035 14.3 0.0 0.22 11.7 0.0 2.2 3 0 0 3 3 3 0 Conjugal transfer protein TrbH KR PF08659.10 GAM35332.1 - 0.036 14.0 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 KR domain Lipase_3 PF01764.25 GAM35333.1 - 7.1e-07 29.2 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 GAM35333.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AIM3 PF17096.5 GAM35334.1 - 0.0058 17.5 0.1 0.0058 17.5 0.1 6.0 5 2 1 6 6 6 1 Altered inheritance of mitochondria protein 3 MFS_1 PF07690.16 GAM35335.1 - 8.5e-25 87.4 54.9 8.7e-25 87.4 48.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM35336.1 - 6.6e-11 41.7 0.1 1.1e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2483 PF10656.9 GAM35337.1 - 0.17 12.1 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2483) Tannase PF07519.11 GAM35338.1 - 2.2e-87 293.9 1.7 3.4e-87 293.3 1.7 1.3 1 1 0 1 1 1 1 Tannase and feruloyl esterase Esterase PF00756.20 GAM35338.1 - 0.0029 17.3 0.0 0.0039 16.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 GAM35338.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MRJP PF03022.16 GAM35339.1 - 3.7e-08 33.1 0.0 5.2e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein NHL PF01436.21 GAM35339.1 - 0.0025 17.8 2.2 1.2 9.4 0.0 3.8 4 0 0 4 4 4 2 NHL repeat SGL PF08450.12 GAM35339.1 - 0.02 14.5 0.4 4.7 6.7 0.0 2.6 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region COesterase PF00135.28 GAM35340.1 - 2.3e-79 267.6 0.1 3e-79 267.2 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM35340.1 - 1.4e-06 28.3 1.1 0.014 15.3 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM35340.1 - 0.031 13.8 0.0 0.085 12.3 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family FAD_binding_3 PF01494.19 GAM35341.1 - 1.1e-16 61.0 0.0 1.6e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM35341.1 - 2.5e-05 24.1 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM35341.1 - 3.7e-05 23.9 0.0 9.4e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM35341.1 - 0.00032 20.0 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM35341.1 - 0.003 18.1 0.0 0.011 16.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM35341.1 - 0.0057 16.7 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 GAM35341.1 - 0.0086 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Mqo PF06039.15 GAM35341.1 - 0.012 14.2 0.1 0.029 12.9 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Mis12 PF05859.12 GAM35344.1 - 1.3e-47 161.2 0.1 2.3e-47 160.4 0.1 1.4 1 0 0 1 1 1 1 Mis12 protein Tho2 PF11262.8 GAM35344.1 - 0.062 12.5 1.7 0.23 10.6 0.1 2.1 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DivIC PF04977.15 GAM35344.1 - 0.55 10.0 4.7 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator CENP-X PF09415.10 GAM35345.1 - 1.7e-28 98.7 0.0 4.1e-28 97.5 0.0 1.7 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 GAM35345.1 - 0.0034 17.6 0.1 0.0077 16.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GET2 PF08690.10 GAM35345.1 - 0.15 11.7 13.6 0.2 11.3 13.6 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Apt1 PF10351.9 GAM35345.1 - 0.51 9.1 15.7 0.62 8.9 15.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 GAM35345.1 - 0.72 9.7 20.3 0.88 9.4 20.3 1.1 1 0 0 1 1 1 0 SPX domain MAP70 PF07058.11 GAM35345.1 - 0.86 8.3 14.3 1.3 7.7 14.3 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 Macoilin PF09726.9 GAM35345.1 - 0.87 8.1 13.0 0.9 8.0 13.0 1.1 1 0 0 1 1 1 0 Macoilin family Dsh_C PF12316.8 GAM35345.1 - 1 9.8 20.1 1.6 9.1 20.1 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal PAP1 PF08601.10 GAM35345.1 - 1.2 8.8 23.4 1.4 8.6 23.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 SOG2 PF10428.9 GAM35345.1 - 2.1 7.5 20.4 2.5 7.2 20.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4551 PF15087.6 GAM35345.1 - 2.1 7.1 14.6 2.5 6.8 14.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 GAM35345.1 - 4.7 5.9 13.6 5.3 5.7 13.6 1.1 1 0 0 1 1 1 0 Presenilin Phosphoesterase PF04185.14 GAM35346.1 - 1.4e-61 208.7 0.3 1.8e-61 208.3 0.3 1.2 1 0 0 1 1 1 1 Phosphoesterase family Cupredoxin_1 PF13473.6 GAM35348.1 - 0.012 15.7 0.1 0.02 15.0 0.1 1.4 1 0 0 1 1 1 0 Cupredoxin-like domain Herpes_capsid PF06112.11 GAM35348.1 - 1.6 8.7 13.4 2.4 8.2 13.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein BTB PF00651.31 GAM35349.1 - 1.4e-17 63.9 0.1 1.2e-08 35.2 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 GAM35350.1 - 7e-07 29.5 0.2 1.9e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain SUN PF03856.13 GAM35351.1 - 2e-77 260.0 7.7 2.8e-77 259.5 7.7 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) NPR3 PF03666.13 GAM35351.1 - 0.73 8.6 4.8 0.92 8.2 4.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Med13_C PF06333.12 GAM35351.1 - 2 7.6 19.3 4 6.6 19.3 1.5 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Presenilin PF01080.17 GAM35351.1 - 6.7 5.4 7.9 9.3 4.9 7.9 1.1 1 0 0 1 1 1 0 Presenilin SPX PF03105.19 GAM35351.1 - 9.6 6.0 26.0 14 5.5 26.0 1.2 1 0 0 1 1 1 0 SPX domain Aldo_ket_red PF00248.21 GAM35353.1 - 1.1e-66 225.0 0.0 1.4e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ist1 PF03398.14 GAM35354.1 - 5.8e-44 149.9 5.2 7.6e-22 78.0 1.6 2.9 3 0 0 3 3 3 2 Regulator of Vps4 activity in the MVB pathway CN_hydrolase PF00795.22 GAM35354.1 - 2e-43 148.6 0.0 2.8e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 GAM35354.1 - 1.2e-24 86.8 0.0 4.3e-24 85.0 0.0 1.9 2 1 0 2 2 2 1 NAD synthase SAPS PF04499.15 GAM35354.1 - 0.022 13.5 0.2 0.04 12.7 0.0 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF5486 PF17588.2 GAM35354.1 - 0.17 11.8 0.1 0.44 10.5 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5486) DUF1601 PF07671.11 GAM35355.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) Clat_adaptor_s PF01217.20 GAM35356.1 - 9.2e-56 187.7 2.0 1.1e-55 187.5 2.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.20 GAM35357.1 - 1.8e-25 90.1 0.2 3.2e-25 89.3 0.2 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIID-18kDa PF02269.16 GAM35358.1 - 9e-33 112.2 0.6 1.1e-31 108.7 0.3 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 GAM35358.1 - 0.038 14.1 0.1 0.097 12.8 0.0 1.8 2 0 0 2 2 2 0 hTAFII28-like protein conserved region Pyrid_ox_like PF16242.5 GAM35359.1 - 2.2e-07 30.6 0.0 3.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like IFR3_antag PF14754.6 GAM35359.1 - 0.18 11.0 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Papain-like auto-proteinase Amidohydro_1 PF01979.20 GAM35360.1 - 3.7e-29 102.1 0.0 7.4e-29 101.1 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM35360.1 - 9.9e-15 55.0 0.3 1.6e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Lar_N PF09861.9 GAM35360.1 - 0.092 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Lactate racemase N-terminal domain zf-C2H2_jaz PF12171.8 GAM35361.1 - 2.2e-08 34.2 0.4 3.9e-08 33.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAM35361.1 - 5.1e-06 26.7 0.5 9.1e-06 25.9 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 GAM35361.1 - 0.00095 19.5 0.4 0.0016 18.8 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 GAM35361.1 - 0.074 13.4 0.7 0.38 11.1 0.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) BIR PF00653.21 GAM35362.1 - 3.6e-46 155.7 5.2 1.9e-22 79.7 0.1 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Tam41_Mmp37 PF09139.11 GAM35363.1 - 7.4e-132 439.7 0.0 9.3e-132 439.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Aminotran_1_2 PF00155.21 GAM35364.1 - 3.1e-62 210.8 0.0 4e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAM35364.1 - 0.019 13.5 0.0 0.057 11.9 0.0 1.7 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 GAM35364.1 - 0.023 13.6 0.0 0.053 12.4 0.0 1.5 2 0 0 2 2 2 0 Allinase bZIP_1 PF00170.21 GAM35365.1 - 3.2e-11 43.2 4.3 6e-11 42.3 4.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAM35365.1 - 0.00012 22.1 5.9 0.00012 22.1 5.9 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAM35365.1 - 0.016 15.7 10.1 0.023 15.2 9.6 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor Prominin PF05478.11 GAM35365.1 - 0.41 8.6 1.0 0.48 8.3 1.0 1.0 1 0 0 1 1 1 0 Prominin CDC45 PF02724.14 GAM35365.1 - 1.2 7.4 7.5 1.4 7.2 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein ketoacyl-synt PF00109.26 GAM35366.1 - 1.7e-69 234.2 0.0 1.3e-67 228.1 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 GAM35366.1 - 2.4e-54 184.6 0.0 3.7e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 GAM35366.1 - 4e-53 180.0 0.0 1.5e-52 178.1 0.0 2.1 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 GAM35366.1 - 2.6e-34 117.8 0.0 7e-34 116.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 GAM35366.1 - 2.6e-33 115.9 0.2 2.1e-32 112.9 0.0 2.4 2 1 0 2 2 2 1 Acyl transferase domain Methyltransf_12 PF08242.12 GAM35366.1 - 2.1e-17 63.7 0.0 6.8e-17 62.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 GAM35366.1 - 6.4e-15 56.4 0.0 9e-14 52.7 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 GAM35366.1 - 3.9e-10 39.8 0.0 1.2e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM35366.1 - 1.8e-08 34.9 0.0 1.2e-07 32.3 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM35366.1 - 5.6e-07 29.5 0.0 1.6e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM35366.1 - 6.8e-07 29.9 0.0 4.5e-06 27.2 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 GAM35366.1 - 1.9e-06 27.5 0.0 6.1e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35366.1 - 1e-05 25.2 0.0 3.5e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 GAM35366.1 - 2.2e-05 23.9 0.0 5.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_zinc_N PF00107.26 GAM35366.1 - 0.00052 20.0 0.0 0.011 15.7 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 GAM35366.1 - 0.0016 18.7 0.0 0.0046 17.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_28 PF02636.17 GAM35366.1 - 0.0031 17.2 0.1 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 GAM35366.1 - 0.043 12.9 0.2 3 6.8 0.0 2.4 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase CMD PF02627.20 GAM35367.1 - 9.3e-08 32.0 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family LrgB PF04172.16 GAM35368.1 - 0.19 11.2 12.0 0.2 11.2 4.9 2.5 2 1 0 2 2 2 0 LrgB-like family Abhydrolase_6 PF12697.7 GAM35369.1 - 1.2e-08 35.9 0.0 1.9e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM35369.1 - 0.00038 20.2 0.2 0.0015 18.3 0.2 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM35369.1 - 0.00085 18.7 0.0 0.002 17.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 GAM35369.1 - 0.018 15.0 0.2 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal AMP-binding PF00501.28 GAM35370.1 - 2.7e-82 276.6 0.0 3.4e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM35370.1 - 3.7e-17 63.1 0.2 7.9e-17 62.0 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltr_RsmB-F PF01189.17 GAM35372.1 - 9e-35 120.1 0.0 6e-27 94.6 0.0 3.0 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 GAM35372.1 - 0.16 12.0 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF2840 PF11000.8 GAM35373.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) RNA_pol_Rpb5_C PF01191.19 GAM35374.1 - 8.8e-34 115.2 0.1 1.5e-33 114.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 GAM35374.1 - 2.6e-26 92.0 0.0 4.1e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 GAM35374.1 - 0.0023 18.0 0.0 0.0055 16.7 0.0 1.6 2 0 0 2 2 2 1 Restriction endonuclease Sld3_N PF18523.1 GAM35374.1 - 0.16 12.1 0.2 0.36 11.0 0.2 1.5 1 0 0 1 1 1 0 Sld3 N-terminal domain ABC_tran_CTD PF16326.5 GAM35375.1 - 0.00035 20.8 3.2 0.00035 20.8 3.2 6.7 3 2 4 7 7 7 3 ABC transporter C-terminal domain Zw10 PF06248.13 GAM35375.1 - 0.0041 15.8 5.5 0.0041 15.8 5.5 2.6 2 1 0 3 3 3 1 Centromere/kinetochore Zw10 CorA PF01544.18 GAM35375.1 - 0.0058 16.0 5.6 0.0058 16.0 5.6 3.7 3 1 1 4 4 4 1 CorA-like Mg2+ transporter protein EzrA PF06160.12 GAM35375.1 - 0.076 11.2 41.6 0.022 12.9 13.3 3.4 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA MtrG PF04210.13 GAM35375.1 - 0.079 12.8 3.0 9 6.2 0.0 3.8 3 1 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Fib_alpha PF08702.10 GAM35375.1 - 0.59 10.3 33.4 2.5 8.3 8.0 4.4 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Osmo_CC PF08946.10 GAM35375.1 - 0.99 9.7 19.2 0.97 9.7 1.9 4.9 4 1 0 4 4 4 0 Osmosensory transporter coiled coil CENP-F_leu_zip PF10473.9 GAM35375.1 - 1 9.4 47.2 0.033 14.2 16.5 4.2 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 GAM35375.1 - 3.6 8.1 71.7 0.12 13.0 18.5 5.0 2 1 3 5 5 5 0 Apg6 coiled-coil region SLATT_fungal PF18142.1 GAM35376.1 - 8.9e-32 109.6 0.2 8.9e-32 109.6 0.2 1.9 2 1 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain DUF948 PF06103.11 GAM35376.1 - 0.00079 19.6 0.1 0.011 16.0 0.0 2.4 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Golgin_A5 PF09787.9 GAM35376.1 - 0.024 14.1 0.3 0.024 14.1 0.3 1.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 Apolipoprotein PF01442.18 GAM35376.1 - 0.07 13.0 8.4 0.29 11.0 8.2 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain V-ATPase_G PF03179.15 GAM35376.1 - 0.077 13.5 0.8 1.8 9.2 0.0 2.4 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF1664 PF07889.12 GAM35376.1 - 0.14 12.2 0.8 0.45 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FUSC PF04632.12 GAM35376.1 - 0.16 10.5 3.2 0.2 10.1 3.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family COG2 PF06148.11 GAM35376.1 - 0.19 11.8 0.8 3.3 7.8 0.1 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Fzo_mitofusin PF04799.13 GAM35376.1 - 0.26 10.8 1.3 0.27 10.8 0.1 1.6 2 0 0 2 2 2 0 fzo-like conserved region Glyco_hydro_35 PF01301.19 GAM35377.1 - 2.9e-96 322.8 0.0 4e-96 322.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 GAM35377.1 - 7.5e-65 218.1 3.1 2.1e-64 216.7 3.1 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 GAM35377.1 - 1.7e-62 209.0 13.4 6.1e-37 126.7 0.4 3.6 3 0 0 3 3 3 3 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 GAM35377.1 - 1.1e-21 76.1 0.3 4.3e-21 74.3 0.4 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 GAM35377.1 - 0.037 13.5 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Sec-ASP3 PF15432.6 GAM35377.1 - 0.17 12.1 0.0 0.57 10.3 0.0 1.9 2 0 0 2 2 2 0 Accessory Sec secretory system ASP3 Yae1_N PF09811.9 GAM35378.1 - 0.065 12.9 4.0 0.065 12.9 4.0 3.1 2 1 0 2 2 2 0 Essential protein Yae1, N terminal DUF3533 PF12051.8 GAM35379.1 - 0.1 11.5 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) PBP1_TM PF14812.6 GAM35379.1 - 0.11 12.9 3.0 0.18 12.2 3.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Adeno_E3_CR2 PF02439.15 GAM35379.1 - 1.2 8.9 4.3 2.4 8.0 4.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Zot PF05707.12 GAM35382.1 - 0.0029 17.3 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF87 PF01935.17 GAM35382.1 - 0.028 14.5 0.0 0.028 14.5 0.0 2.2 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 GAM35382.1 - 0.061 13.6 0.0 21 5.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Abhydrolase_2 PF02230.16 GAM35383.1 - 3.2e-13 50.0 0.0 9.1e-13 48.5 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DEAD PF00270.29 GAM35384.1 - 1.7e-41 141.9 0.0 3.2e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM35384.1 - 1.3e-23 83.5 0.1 1.3e-22 80.3 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM35384.1 - 6.5e-06 26.3 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAM35384.1 - 0.0078 15.4 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase MFS_1 PF07690.16 GAM35385.1 - 1.9e-14 53.4 45.7 1.9e-14 53.4 45.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM35385.1 - 2.2e-07 30.1 14.3 2.2e-07 30.1 14.3 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter Aldedh PF00171.22 GAM35387.1 - 1.2e-129 432.8 0.3 1.5e-129 432.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAM35387.1 - 0.019 14.4 0.0 0.045 13.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Adenylsucc_synt PF00709.21 GAM35389.1 - 4e-167 556.4 0.0 5.5e-167 555.9 0.0 1.2 1 0 0 1 1 1 1 Adenylosuccinate synthetase DnaJ PF00226.31 GAM35389.1 - 3.9e-22 78.1 0.2 3.9e-22 78.1 0.2 2.2 3 0 0 3 3 3 1 DnaJ domain Fungal_trans PF04082.18 GAM35390.1 - 6.7e-26 90.9 0.0 1.2e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM35390.1 - 8.4e-08 32.2 12.2 1.3e-07 31.6 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S10 PF00338.22 GAM35390.1 - 0.008 16.4 0.1 0.017 15.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e MFS_1 PF07690.16 GAM35391.1 - 3.8e-41 141.2 34.4 6.3e-38 130.6 17.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM35391.1 - 1.1e-09 37.7 5.0 1.1e-09 37.7 5.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 GAM35391.1 - 5.4e-05 22.2 0.1 5.4e-05 22.2 0.1 3.2 1 1 3 4 4 4 1 MFS_1 like family TRI12 PF06609.13 GAM35391.1 - 7.3e-05 21.4 1.1 0.00012 20.7 1.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 GAM35391.1 - 0.5 8.7 8.5 0.56 8.5 0.7 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector GTP1_OBG PF01018.22 GAM35392.1 - 7.4e-38 129.6 6.7 3.4e-30 104.7 5.7 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 GAM35392.1 - 8.4e-22 77.4 0.0 1.3e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM35392.1 - 2.7e-07 30.2 0.1 6.6e-07 29.0 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAM35392.1 - 0.024 14.2 0.0 5 6.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 GAM35392.1 - 0.064 12.2 0.0 0.44 9.5 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 GAM35392.1 - 0.21 11.1 0.0 1.4 8.4 0.0 2.2 3 0 0 3 3 3 0 ADP-ribosylation factor family cobW PF02492.19 GAM35392.1 - 0.21 11.1 0.0 1.6 8.3 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 GAM35392.1 - 0.26 11.8 4.2 0.28 11.7 0.0 2.4 2 1 1 3 3 3 0 ABC transporter FAD_binding_3 PF01494.19 GAM35393.1 - 1.4e-23 83.7 0.0 4.4e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAM35393.1 - 6e-05 23.2 1.0 0.00013 22.1 0.3 2.1 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM35393.1 - 0.00028 20.2 0.2 0.00042 19.7 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM35393.1 - 0.0008 18.7 0.2 0.0023 17.2 0.1 1.7 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM35393.1 - 0.00084 18.5 1.4 0.008 15.3 1.1 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein SE PF08491.10 GAM35393.1 - 0.0018 17.4 0.0 0.0057 15.7 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase HI0933_like PF03486.14 GAM35393.1 - 0.021 13.5 0.1 0.16 10.6 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 GAM35393.1 - 0.11 12.0 1.0 0.52 9.8 0.8 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 GAM35393.1 - 0.13 11.4 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Ccdc124 PF06244.12 GAM35394.1 - 1.6e-26 93.4 16.0 1.6e-26 93.4 16.0 2.7 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 124 /Oxs1 Cupin_8 PF13621.6 GAM35394.1 - 2.5e-26 92.9 0.0 1.1e-25 90.8 0.0 2.1 1 1 1 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 GAM35394.1 - 2.7e-05 23.8 0.0 0.055 12.9 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein Kei1 PF08552.11 GAM35394.1 - 1.8 8.4 4.2 4.9 7.0 4.2 1.7 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 WD40 PF00400.32 GAM35395.1 - 4.7e-17 62.0 15.9 0.0012 19.6 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat UQ_con PF00179.26 GAM35397.1 - 9.9e-12 44.7 0.2 1.9e-11 43.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAM35397.1 - 0.039 14.2 0.2 0.086 13.1 0.2 1.5 1 0 0 1 1 1 0 RWD domain Aldedh PF00171.22 GAM35398.1 - 1.8e-185 616.9 0.2 2e-185 616.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Homeobox_KN PF05920.11 GAM35399.1 - 3.8e-16 58.7 1.9 3.8e-16 58.7 1.9 2.4 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 GAM35399.1 - 4.8e-05 23.1 0.4 0.00013 21.7 0.4 1.8 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 GAM35399.1 - 6.7e-05 23.1 17.0 0.18 12.3 0.8 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM35399.1 - 0.0023 18.6 1.0 0.0023 18.6 1.0 5.4 5 0 0 5 5 5 2 C2H2-type zinc finger ImpA_N PF06812.12 GAM35399.1 - 0.057 13.5 0.1 0.23 11.5 0.1 2.1 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system zf-H2C2_2 PF13465.6 GAM35399.1 - 6.6 7.3 8.7 18 6.0 0.2 4.1 4 0 0 4 4 4 0 Zinc-finger double domain KR PF08659.10 GAM35400.1 - 5.1e-29 101.5 0.6 3.1e-28 98.9 0.0 1.9 2 0 0 2 2 2 1 KR domain DprA_WH PF17782.1 GAM35400.1 - 0.0079 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 DprA winged helix domain Peptidase_C13 PF01650.18 GAM35401.1 - 8.7e-41 140.1 0.0 1.2e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family CDC45 PF02724.14 GAM35402.1 - 1.8e-174 581.6 16.7 1.4e-172 575.4 16.7 3.0 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.12 GAM35402.1 - 0.00073 19.3 7.7 0.0013 18.6 7.7 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 GAM35402.1 - 0.013 14.8 14.6 0.026 13.9 14.6 1.4 1 0 0 1 1 1 0 BUD22 FAM60A PF15396.6 GAM35402.1 - 0.04 13.9 2.2 0.088 12.8 2.2 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Spore_coat_CotO PF14153.6 GAM35402.1 - 0.057 13.3 2.3 0.086 12.8 2.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Nop14 PF04147.12 GAM35402.1 - 0.063 11.5 9.7 0.091 11.0 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 GAM35402.1 - 0.11 12.1 3.1 0.22 11.2 3.1 1.5 1 0 0 1 1 1 0 FAM176 family RR_TM4-6 PF06459.12 GAM35402.1 - 0.67 9.7 7.6 1 9.1 7.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 GAM35402.1 - 0.69 8.6 2.8 1 8.1 2.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pox_Ag35 PF03286.14 GAM35402.1 - 0.99 9.2 14.2 2 8.2 14.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PGA2 PF07543.12 GAM35402.1 - 1.7 8.6 17.8 2.4 8.1 16.3 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 RNA_pol_Rpc4 PF05132.14 GAM35402.1 - 2.1 8.8 4.8 4.5 7.7 4.8 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Vfa1 PF08432.10 GAM35402.1 - 3.8 7.8 14.0 7.2 6.9 13.7 1.6 2 0 0 2 2 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_3_Rpc31 PF11705.8 GAM35402.1 - 4 7.6 18.2 1.2 9.4 14.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Afi1 PF07792.12 GAM35402.1 - 5.4 7.5 10.3 11 6.5 10.3 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF1168 PF06658.12 GAM35402.1 - 6.8 6.5 25.2 31 4.4 23.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) NPR3 PF03666.13 GAM35402.1 - 7.1 5.3 10.0 12 4.5 10.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 GAM35403.1 - 2.2e-57 194.8 0.0 2.4e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein NOGCT PF08155.11 GAM35403.1 - 0.038 14.0 0.1 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 NOGCT (NUC087) domain NmrA PF05368.13 GAM35405.1 - 4.3e-28 98.4 0.0 7e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Fungal_trans PF04082.18 GAM35405.1 - 1.3e-14 53.9 0.1 4.5e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 GAM35405.1 - 1e-11 45.1 0.0 2.2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 GAM35405.1 - 0.00016 21.7 0.1 0.0004 20.4 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAM35405.1 - 0.00072 19.1 0.0 0.0019 17.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM35405.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CENP-O PF09496.10 GAM35405.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component DUF1799 PF08809.11 GAM35405.1 - 0.17 12.1 0.3 1.9 8.8 0.0 2.7 3 0 0 3 3 3 0 Phage related hypothetical protein (DUF1799) Glyco_hydro_47 PF01532.20 GAM35406.1 - 1.3e-134 449.5 0.1 1.5e-134 449.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Histidinol_dh PF00815.20 GAM35407.1 - 4.1e-162 539.9 3.8 4.5e-162 539.7 2.6 1.6 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.18 GAM35407.1 - 2.1e-24 85.1 0.3 4.8e-24 84.0 0.3 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 GAM35407.1 - 1.2e-15 57.7 0.1 5.1e-15 55.7 0.1 2.2 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG-like PF12643.7 GAM35407.1 - 0.11 12.7 0.8 0.25 11.6 0.8 1.6 1 0 0 1 1 1 0 MazG-like family Utp11 PF03998.13 GAM35408.1 - 5.7e-59 200.0 34.0 7.7e-59 199.6 34.0 1.2 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 GAM35408.1 - 0.022 14.1 2.1 0.066 12.5 0.2 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 CENP-B_dimeris PF09026.10 GAM35408.1 - 8.8 6.8 19.3 13 6.3 9.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TFIID-31kDa PF02291.15 GAM35410.1 - 7.8e-45 151.9 0.0 1e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit LNS2 PF08235.13 GAM35411.1 - 7.4e-97 323.3 0.0 1e-96 322.8 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 GAM35411.1 - 1.3e-42 143.9 0.0 4.4e-42 142.2 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 GAM35411.1 - 0.0098 15.5 0.1 0.23 11.0 0.0 2.5 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) rhaM PF05336.13 GAM35412.1 - 5.4e-36 122.9 0.1 6.1e-36 122.8 0.1 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase HTH_Bact PF18768.1 GAM35412.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix bacterial domain fn3 PF00041.21 GAM35413.1 - 2.9e-06 27.5 0.0 1.4e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III domain ALIX_LYPXL_bnd PF13949.6 GAM35413.1 - 0.07 12.4 32.4 0.14 11.4 32.4 1.4 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Taxilin PF09728.9 GAM35413.1 - 0.16 11.1 50.3 0.43 9.7 0.3 3.0 2 1 0 2 2 2 0 Myosin-like coiled-coil protein APG6_N PF17675.1 GAM35413.1 - 2.6 8.6 58.3 0.35 11.4 13.4 3.5 1 1 2 3 3 3 0 Apg6 coiled-coil region Thg1C PF14413.6 GAM35414.1 - 1.6e-53 180.0 0.8 2.2e-53 179.6 0.8 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 GAM35414.1 - 5.2e-53 178.4 0.0 9.4e-53 177.5 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase PepSY_TM_like_2 PF16357.5 GAM35414.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like WD40 PF00400.32 GAM35416.1 - 1.3e-13 51.1 0.0 0.042 14.7 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 GAM35416.1 - 0.0037 16.1 0.0 2.5 6.7 0.0 2.6 3 0 0 3 3 3 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 GAM35416.1 - 0.0095 16.2 0.0 9.7 6.6 0.0 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_23 PF13489.6 GAM35417.1 - 2.9e-15 56.5 0.0 5.4e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM35417.1 - 5.9e-08 33.3 0.0 1.6e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM35417.1 - 3.4e-05 24.5 0.0 0.00015 22.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM35417.1 - 4.3e-05 24.1 0.0 0.00011 22.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM35417.1 - 0.0016 18.3 0.0 0.0042 16.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAM35417.1 - 0.0026 17.3 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 GAM35417.1 - 0.022 14.9 0.0 0.053 13.6 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 GAM35417.1 - 0.023 14.1 3.0 0.026 14.0 0.0 2.3 3 0 0 3 3 2 0 Putative methyltransferase Ubie_methyltran PF01209.18 GAM35417.1 - 0.059 12.7 0.0 0.28 10.5 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 GAM35417.1 - 0.064 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 GAM35417.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase WD40 PF00400.32 GAM35418.1 - 1.1e-14 54.6 8.3 1.7e-05 25.5 0.2 5.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM35418.1 - 6.7e-10 39.1 1.0 1.2e-05 25.5 0.0 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM35418.1 - 0.00014 21.9 0.0 0.92 9.4 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Peptidase_C3 PF00548.20 GAM35418.1 - 0.062 13.2 0.0 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 3C cysteine protease (picornain 3C) Cytochrom_D1 PF02239.16 GAM35418.1 - 0.072 11.6 0.0 0.33 9.4 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain RNA_pol_Rpb1_1 PF04997.12 GAM35419.1 - 2.5e-111 372.0 0.1 3.8e-111 371.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 GAM35419.1 - 4e-103 344.5 0.2 6.2e-103 343.9 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAM35419.1 - 6.2e-68 228.2 0.0 2.1e-66 223.2 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 GAM35419.1 - 1.5e-63 214.1 0.9 3.7e-63 212.8 0.9 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 GAM35419.1 - 1.2e-47 161.7 0.0 4.2e-47 160.0 0.0 2.0 2 0 0 2 2 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 GAM35419.1 - 2.7e-45 153.7 8.0 7.3e-45 152.3 8.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 GAM35419.1 - 6e-36 122.7 0.2 1.8e-35 121.1 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Sel1 PF08238.12 GAM35419.1 - 7.3e-33 112.3 29.6 5.3e-07 30.1 0.5 10.8 10 0 0 10 10 10 7 Sel1 repeat RNA_pol_Rpb1_R PF05001.13 GAM35419.1 - 7.2e-08 32.4 187.1 0.031 14.6 0.9 13.9 12 2 2 14 14 13 12 RNA polymerase Rpb1 C-terminal repeat Mei5 PF10376.9 GAM35419.1 - 0.00011 22.1 3.8 0.00026 20.9 3.8 1.6 1 0 0 1 1 1 1 Double-strand recombination repair protein DUF4763 PF15960.5 GAM35419.1 - 0.17 11.2 2.0 0.36 10.1 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Acyl-CoA_dh_2 PF08028.11 GAM35419.1 - 0.75 10.1 3.4 2.1 8.6 3.4 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain SMBP PF16785.5 GAM35419.1 - 1.6 9.0 9.8 1.8 8.8 0.3 3.6 4 0 0 4 4 3 0 Small metal-binding protein Glyco_hydro_1 PF00232.18 GAM35420.1 - 3.7e-156 520.1 0.0 4.4e-156 519.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Kelch_4 PF13418.6 GAM35421.1 - 4.5e-26 90.6 9.5 1.5e-06 28.1 0.0 4.8 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM35421.1 - 4.1e-25 87.3 0.8 1.2e-06 28.3 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 GAM35421.1 - 2.2e-22 78.5 3.6 2.8e-05 24.2 0.1 4.9 3 1 1 4 4 4 4 Kelch motif Kelch_2 PF07646.15 GAM35421.1 - 4.2e-22 77.2 2.9 8.3e-07 28.7 0.1 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 GAM35421.1 - 1.2e-18 66.4 0.2 6.7e-06 25.6 0.1 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 GAM35421.1 - 1.2e-18 66.9 10.5 2e-08 34.3 0.2 5.5 6 0 0 6 6 6 4 Galactose oxidase, central domain BTB PF00651.31 GAM35421.1 - 5.4e-09 36.3 0.1 9.3e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain ANAPC4_WD40 PF12894.7 GAM35422.1 - 3.3e-16 59.4 4.4 6.1e-06 26.4 0.1 4.3 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAM35422.1 - 8.5e-15 54.9 18.2 0.00037 21.2 0.1 6.5 6 1 1 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAM35422.1 - 1e-05 24.7 0.0 0.00087 18.3 0.0 3.0 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAM35422.1 - 0.00033 20.6 0.3 0.03 14.2 0.2 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A MFS_1 PF07690.16 GAM35423.1 - 2.8e-29 102.2 31.4 4e-29 101.7 31.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Pox_A14 PF05767.12 GAM35423.1 - 0.048 13.8 0.4 0.57 10.4 0.0 2.8 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 PMP1_2 PF08114.11 GAM35423.1 - 0.14 11.9 2.0 1.1 9.1 0.1 2.9 3 0 0 3 3 3 0 ATPase proteolipid family TFIIA PF03153.13 GAM35424.1 - 2e-79 268.5 0.1 2.8e-79 268.0 0.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Zn_clus PF00172.18 GAM35425.1 - 9.7e-11 41.6 7.5 1.9e-10 40.7 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM35425.1 - 0.0012 18.0 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain UPF0239 PF06783.11 GAM35425.1 - 0.14 12.4 0.0 0.4 10.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Chlam_OMP3 PF03503.13 GAM35425.1 - 2.4 8.5 7.5 4 7.8 5.0 2.5 3 0 0 3 3 3 0 Chlamydia cysteine-rich outer membrane protein 3 Acetyltransf_7 PF13508.7 GAM35426.1 - 0.032 14.7 0.0 0.062 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM35426.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Arf PF00025.21 GAM35427.1 - 7.9e-66 220.8 0.6 8.8e-66 220.7 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 GAM35427.1 - 3.6e-13 49.4 3.2 2.8e-07 30.0 0.9 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 GAM35427.1 - 4.6e-12 46.2 0.0 6.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAM35427.1 - 5.3e-11 42.4 0.0 6.2e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAM35427.1 - 3.6e-10 39.6 0.0 4.3e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAM35427.1 - 3.6e-08 33.1 0.0 4.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAM35427.1 - 5e-08 33.0 0.0 7.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM35427.1 - 8.5e-05 22.2 0.0 0.0024 17.4 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAM35427.1 - 0.025 14.1 0.3 0.063 12.8 0.3 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.19 GAM35427.1 - 0.07 12.7 0.0 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF4045 PF13254.6 GAM35428.1 - 6.3e-135 451.0 40.9 6.3e-135 451.0 40.9 5.9 4 2 1 5 5 5 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 GAM35428.1 - 8.5e-10 38.4 0.0 0.0012 18.7 0.0 3.7 3 0 0 3 3 3 3 Gelsolin repeat ALO PF04030.14 GAM35430.1 - 5.4e-95 318.1 0.1 7.8e-95 317.6 0.1 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 GAM35430.1 - 1.7e-32 112.1 0.1 2.5e-32 111.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DnaJ PF00226.31 GAM35431.1 - 4.6e-16 58.7 0.9 1.2e-15 57.3 0.9 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 GAM35431.1 - 7.6e-08 31.8 0.0 0.0015 17.7 0.0 2.1 2 0 0 2 2 2 2 Sec63 Brl domain Imm_superinfect PF14373.6 GAM35431.1 - 0.057 13.3 0.4 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 Superinfection immunity protein REV PF00424.18 GAM35432.1 - 0.022 14.8 0.3 0.031 14.3 0.3 1.2 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Peptidase_M24 PF00557.24 GAM35433.1 - 2.4e-58 197.3 0.2 3.2e-58 196.8 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 GAM35433.1 - 4.5e-23 81.3 0.0 8.2e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain GFO_IDH_MocA PF01408.22 GAM35434.1 - 3.9e-20 72.9 0.0 1.1e-19 71.4 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CTP_transf_like PF01467.26 GAM35434.1 - 3.6e-11 43.4 0.0 7.8e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like PAN_1 PF00024.26 GAM35434.1 - 2.1e-07 30.8 20.3 0.00024 21.0 0.1 4.2 4 0 0 4 4 4 3 PAN domain Phage_holin_2_1 PF04971.12 GAM35434.1 - 8.3e-05 22.5 2.7 0.36 10.9 0.7 2.6 2 0 0 2 2 2 2 Bacteriophage P21 holin S FAD_syn PF06574.12 GAM35434.1 - 0.0042 17.0 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 FAD synthetase 2-Hacid_dh_C PF02826.19 GAM35434.1 - 0.11 11.9 0.1 0.37 10.1 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PAN_4 PF14295.6 GAM35434.1 - 0.21 11.5 21.6 0.016 15.1 2.0 3.9 3 0 0 3 3 3 0 PAN domain SPRY PF00622.28 GAM35435.1 - 1.6e-19 70.2 0.0 2.4e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 SPRY domain PDEase_II PF02112.15 GAM35436.1 - 3.3e-54 184.3 0.0 6.5e-25 87.9 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 GAM35436.1 - 0.018 15.0 0.2 0.046 13.7 0.2 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM35436.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Tmemb_cc2 PF10267.9 GAM35436.1 - 0.23 10.6 0.9 0.32 10.1 0.9 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Amidase PF01425.21 GAM35437.1 - 1.2e-79 268.4 0.0 2.4e-79 267.4 0.0 1.4 1 1 0 1 1 1 1 Amidase GWT1 PF06423.12 GAM35438.1 - 6.7e-40 136.6 0.9 6.7e-40 136.6 0.9 2.3 2 1 1 3 3 3 1 GWT1 PDR_CDR PF06422.12 GAM35438.1 - 0.24 11.3 1.5 0.41 10.6 0.1 2.1 2 0 0 2 2 2 0 CDR ABC transporter Dioxygenase_C PF00775.21 GAM35439.1 - 1.4e-07 31.1 0.1 2.4e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase HIP1_clath_bdg PF16515.5 GAM35439.1 - 0.14 12.8 1.1 0.22 12.2 1.1 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Aldedh PF00171.22 GAM35440.1 - 6.7e-72 242.5 0.0 3.8e-33 114.7 0.0 3.1 1 1 2 3 3 3 3 Aldehyde dehydrogenase family Amino_oxidase PF01593.24 GAM35440.1 - 9.3e-47 160.3 0.0 1.3e-46 159.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM35440.1 - 1.2e-12 47.9 0.1 4.5e-12 46.0 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM35440.1 - 3.6e-07 29.6 0.9 6.5e-07 28.8 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM35440.1 - 4.7e-06 26.4 0.4 3.3e-05 23.6 0.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAM35440.1 - 4.7e-06 26.2 0.6 7.3e-06 25.6 0.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAM35440.1 - 1.2e-05 24.7 0.3 0.015 14.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM35440.1 - 2.2e-05 23.4 0.1 0.0002 20.2 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAM35440.1 - 0.0026 17.0 0.1 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM35440.1 - 0.0033 16.6 0.3 0.1 11.6 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 GAM35440.1 - 0.0047 16.2 0.3 0.0084 15.4 0.3 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 GAM35440.1 - 0.019 14.2 0.5 0.03 13.6 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 GAM35440.1 - 0.026 13.6 0.1 0.15 11.1 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 GAM35440.1 - 0.032 14.8 0.3 0.032 14.8 0.3 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase bZIP_1 PF00170.21 GAM35441.1 - 7.4e-05 22.8 7.8 0.00016 21.7 7.8 1.5 1 1 0 1 1 1 1 bZIP transcription factor Mito_fiss_reg PF05308.11 GAM35441.1 - 8.9e-05 22.7 9.6 8.9e-05 22.7 9.6 1.9 1 1 0 2 2 2 1 Mitochondrial fission regulator Fez1 PF06818.15 GAM35441.1 - 0.0012 19.4 0.6 0.0018 18.7 0.6 1.3 1 0 0 1 1 1 1 Fez1 MAD PF05557.13 GAM35441.1 - 0.0018 16.8 4.9 0.0025 16.3 4.9 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein bZIP_2 PF07716.15 GAM35441.1 - 0.0024 17.9 12.2 0.015 15.4 9.2 2.3 1 1 1 2 2 2 2 Basic region leucine zipper YabA PF06156.13 GAM35441.1 - 0.0029 18.2 2.5 0.0062 17.2 2.5 1.5 1 0 0 1 1 1 1 Initiation control protein YabA BMFP PF04380.13 GAM35441.1 - 0.038 14.5 1.1 0.038 14.5 1.1 1.8 2 0 0 2 2 2 0 Membrane fusogenic activity FapA PF03961.13 GAM35441.1 - 0.11 11.1 1.0 0.14 10.7 1.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2937 PF11157.8 GAM35441.1 - 0.39 10.4 2.9 0.59 9.8 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Sugar_tr PF00083.24 GAM35442.1 - 1.9e-106 356.7 24.2 2.3e-106 356.4 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM35442.1 - 4.8e-20 71.8 19.1 4.8e-20 71.8 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM35443.1 - 2.3e-82 277.3 26.9 2.6e-82 277.1 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM35443.1 - 6e-20 71.5 20.1 6e-20 71.5 20.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5373 PF17343.2 GAM35443.1 - 0.15 11.9 7.4 0.34 10.7 7.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5373) Acyl-CoA_dh_1 PF00441.24 GAM35444.1 - 1.1e-38 132.8 7.8 1.7e-38 132.2 7.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAM35444.1 - 2.2e-30 105.6 1.6 3.3e-30 105.0 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAM35444.1 - 1.4e-24 86.1 0.0 3.1e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAM35444.1 - 3e-16 59.9 3.1 4.8e-16 59.3 3.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 GAM35444.1 - 0.035 13.8 0.0 0.083 12.5 0.0 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Cellulase PF00150.18 GAM35445.1 - 5.1e-36 124.6 0.8 4.4e-35 121.5 0.3 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 GAM35445.1 - 1.6e-18 66.6 0.1 3.1e-16 59.3 0.1 2.5 2 0 0 2 2 2 2 Carbohydrate binding domain X2 Senescence PF06911.12 GAM35446.1 - 2.5e-54 184.4 2.8 3.8e-54 183.8 2.8 1.3 1 0 0 1 1 1 1 Senescence-associated protein F-box PF00646.33 GAM35447.1 - 0.00037 20.3 0.0 0.00072 19.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAM35447.1 - 0.082 12.8 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.25 GAM35448.1 - 1.9e-63 214.3 0.0 3.2e-63 213.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM35448.1 - 7.7e-35 120.4 0.0 4.8e-29 101.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAM35448.1 - 5.8e-07 29.1 0.1 0.0015 17.9 0.1 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 GAM35448.1 - 0.00011 22.3 0.0 0.0006 19.8 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAM35448.1 - 0.014 15.0 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 GAM35448.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAM35448.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Bap31 PF05529.12 GAM35450.1 - 4.9e-47 159.2 9.3 6.5e-47 158.8 9.3 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 GAM35450.1 - 2.5e-15 56.2 5.4 4.6e-15 55.3 5.4 1.5 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 GAM35450.1 - 0.011 15.4 2.6 0.087 12.6 0.3 3.1 3 0 0 3 3 3 0 Septum formation initiator Csm1_N PF18504.1 GAM35450.1 - 0.062 13.6 0.2 0.12 12.7 0.2 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain CAMSAP_CC1 PF17095.5 GAM35450.1 - 3.8 7.4 6.8 5.6 6.9 2.1 2.5 1 1 1 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin Dus PF01207.17 GAM35451.1 - 5.5e-41 140.6 0.0 1.4e-29 103.2 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 GAM35451.1 - 2.8e-07 30.4 5.4 0.0035 17.4 0.9 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 GAM35451.1 - 1.2e-06 28.2 3.6 8.6e-05 22.2 0.4 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 GAM35451.1 - 3.8e-06 26.7 4.1 0.0039 17.1 0.6 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMM1 PF10296.9 GAM35451.1 - 8.1e-06 25.1 1.0 1.9e-05 23.9 0.0 2.1 3 0 0 3 3 3 1 Maintenance of mitochondrial morphology protein 1 Torus PF16131.5 GAM35451.1 - 0.00033 21.3 6.6 0.39 11.4 2.2 2.8 1 1 1 2 2 2 2 Torus domain Mis14 PF08641.12 GAM35451.1 - 0.16 12.3 7.2 0.47 10.8 1.2 2.8 2 0 0 2 2 2 0 Kinetochore protein Mis14 like zf-CCCH_2 PF14608.6 GAM35451.1 - 7 7.3 5.9 7 7.3 0.5 2.7 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-C2H2 PF00096.26 GAM35452.1 - 7e-05 23.1 10.8 0.087 13.3 1.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 GAM35452.1 - 0.00012 22.3 1.0 0.056 13.6 0.0 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 GAM35452.1 - 0.00063 20.4 12.4 0.037 14.9 1.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAM35452.1 - 0.024 15.1 0.5 0.024 15.1 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 GAM35452.1 - 0.53 10.6 5.9 1.4 9.3 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF4719 PF15843.5 GAM35452.1 - 0.6 10.2 8.0 2.2 8.3 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4719) DEAD PF00270.29 GAM35453.1 - 1.1e-48 165.3 0.0 2.9e-48 164.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM35453.1 - 3.8e-31 107.7 0.3 3.9e-29 101.2 0.2 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 GAM35453.1 - 0.00052 18.9 1.1 0.0041 15.9 0.0 2.8 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SLT PF01464.20 GAM35454.1 - 0.023 14.3 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Transglycosylase SLT domain Fimbrial_K88 PF02432.15 GAM35454.1 - 0.034 14.1 7.4 0.4 10.6 0.1 2.7 2 1 1 3 3 3 0 Fimbrial, major and minor subunit Lysozyme_like PF13702.6 GAM35454.1 - 0.071 12.8 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Lysozyme-like HMGL-like PF00682.19 GAM35455.1 - 2e-81 273.4 0.0 3.1e-81 272.8 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 GAM35455.1 - 2.1e-21 76.2 0.0 5.5e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF4094 PF13334.6 GAM35455.1 - 0.068 13.6 0.0 0.56 10.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) V-SNARE PF05008.15 GAM35455.1 - 0.31 11.5 3.2 0.7 10.3 3.2 1.6 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Spore_III_AB PF09548.10 GAM35455.1 - 0.76 9.9 3.3 0.93 9.6 2.1 1.7 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) AMP-binding PF00501.28 GAM35457.1 - 1.2e-67 228.3 0.9 1.2e-37 129.5 0.0 3.6 2 2 0 2 2 2 2 AMP-binding enzyme Ribosomal_S7 PF00177.21 GAM35458.1 - 4.7e-35 120.4 3.1 6e-35 120.1 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.12 GAM35459.1 - 1.3e-88 297.8 64.3 6.2e-88 295.5 53.5 3.1 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 GAM35459.1 - 5.6e-17 61.8 0.0 1.7e-16 60.3 0.0 1.9 1 0 0 1 1 1 1 NUC130/3NT domain Fungal_trans_2 PF11951.8 GAM35460.1 - 3.8e-07 29.2 0.5 7.4e-07 28.3 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.25 GAM35461.1 - 2.3e-19 69.6 0.3 3.2e-19 69.2 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM35461.1 - 5.7e-12 45.9 0.1 1e-11 45.1 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 GAM35461.1 - 4e-10 39.6 0.1 5.6e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAM35461.1 - 0.047 13.1 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAM35461.1 - 0.1 12.6 0.1 0.94 9.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase YqgC PF17430.2 GAM35461.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized YqgC-like RNR_inhib PF08591.10 GAM35462.1 - 3.4e-24 86.2 0.2 3.4e-24 86.2 0.2 2.5 3 0 0 3 3 3 1 Ribonucleotide reductase inhibitor HIF-1 PF11413.8 GAM35462.1 - 0.26 10.7 2.4 0.58 9.6 2.4 1.5 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 Ank_5 PF13857.6 GAM35463.1 - 3.9e-07 30.2 0.0 0.0021 18.3 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM35463.1 - 5.5e-07 30.1 0.0 1.2e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) CorA PF01544.18 GAM35463.1 - 2e-05 24.1 0.7 4.7e-05 22.9 0.7 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ank_4 PF13637.6 GAM35463.1 - 0.00022 21.7 0.0 0.0014 19.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM35463.1 - 0.001 19.3 0.0 0.0077 16.7 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAM35463.1 - 0.0017 18.7 0.0 0.072 13.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Peptidase_S49_N PF08496.10 GAM35463.1 - 1.6 8.8 3.8 1.4 9.0 0.2 2.5 2 1 0 2 2 2 0 Peptidase family S49 N-terminal TFR_dimer PF04253.15 GAM35464.1 - 9.4e-26 90.3 0.0 1.7e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 GAM35464.1 - 1.7e-16 60.5 0.1 1.6e-15 57.3 0.1 2.1 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 GAM35464.1 - 2.2e-12 46.8 0.1 7.3e-12 45.2 0.1 1.9 1 1 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 GAM35464.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.7 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Peptidase_M20 PF01546.28 GAM35465.1 - 1.1e-25 90.5 0.0 2e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM35465.1 - 0.00049 20.0 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAM35465.1 - 0.0016 18.1 0.0 0.0047 16.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 SBP_bac_5 PF00496.22 GAM35465.1 - 0.16 10.9 0.0 0.38 9.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 5 Middle MFS_1 PF07690.16 GAM35466.1 - 9.7e-31 107.0 39.0 9.7e-31 107.0 39.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Dot_icm_IcmQ PF09475.10 GAM35466.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) ATP1G1_PLM_MAT8 PF02038.16 GAM35466.1 - 3.6 7.1 5.1 5.4 6.5 0.1 2.7 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Glyoxalase_6 PF18029.1 GAM35467.1 - 1e-05 26.2 0.0 1.4e-05 25.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 GAM35467.1 - 5e-05 23.5 0.0 0.00011 22.4 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HSP70 PF00012.20 GAM35468.1 - 3.3e-62 210.5 11.3 5.5e-60 203.2 0.2 3.0 2 1 1 3 3 3 2 Hsp70 protein DUF4559 PF15112.6 GAM35468.1 - 1.8 8.2 5.9 0.78 9.4 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Mucin PF01456.17 GAM35468.1 - 3.8 7.5 28.7 0.32 11.0 7.7 3.6 3 0 0 3 3 3 0 Mucin-like glycoprotein Tubulin_3 PF14881.6 GAM35469.1 - 3.4e-85 284.3 0.1 1.6e-84 282.1 0.1 1.9 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.9 GAM35469.1 - 8.7e-44 148.6 0.0 2e-43 147.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 GAM35469.1 - 0.00057 20.1 0.0 0.49 10.6 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain DUF2347 PF09804.9 GAM35471.1 - 5.6e-106 354.3 0.0 7.4e-106 353.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 GAM35471.1 - 7.4e-57 192.8 0.1 1.7e-56 191.6 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 GAM35471.1 - 7.1e-05 21.7 0.0 0.0051 15.6 0.0 2.5 2 1 0 2 2 2 2 Transport protein Avl9 SPA PF08616.10 GAM35471.1 - 0.00055 19.9 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis EBP PF05241.12 GAM35472.1 - 1.5e-46 158.1 6.0 1.7e-46 157.9 6.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein SNF2_N PF00176.23 GAM35474.1 - 5.9e-58 196.2 0.0 9.7e-58 195.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM35474.1 - 3.6e-15 56.3 0.0 8.5e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM35474.1 - 2.1e-09 37.6 0.3 1.6e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM35474.1 - 6.7e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 GAM35474.1 - 0.0026 17.5 0.0 0.0058 16.3 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF572 PF04502.13 GAM35474.1 - 0.11 12.1 6.7 0.23 11.0 6.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Aldo_ket_red PF00248.21 GAM35475.1 - 7.6e-69 232.1 0.0 8.7e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AA_permease_2 PF13520.6 GAM35476.1 - 1.1e-46 159.6 49.5 1.4e-46 159.3 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM35476.1 - 1.6e-24 86.4 42.1 2.1e-24 86.0 42.1 1.1 1 0 0 1 1 1 1 Amino acid permease MerE PF05052.12 GAM35476.1 - 0.0038 17.1 0.9 0.023 14.6 0.9 2.4 1 0 0 1 1 1 1 MerE protein SID-1_RNA_chan PF13965.6 GAM35476.1 - 0.23 9.8 8.5 0.014 13.8 1.4 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 EMC3_TMCO1 PF01956.16 GAM35477.1 - 0.037 13.8 4.4 0.54 10.0 0.0 2.5 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like SnoaL_2 PF12680.7 GAM35478.1 - 6.4e-06 26.7 0.0 7.1e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Beta-lactamase PF00144.24 GAM35479.1 - 3.1e-51 174.6 0.4 3.8e-51 174.3 0.4 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 GAM35479.1 - 0.027 13.9 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Peptidase_S13 PF02113.15 GAM35479.1 - 0.31 9.7 0.4 0.64 8.7 0.2 1.6 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family DUF1343 PF07075.11 GAM35481.1 - 1.9e-118 395.9 0.0 2.8e-118 395.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1343) BcrAD_BadFG PF01869.20 GAM35481.1 - 1.9e-17 63.7 0.8 3.2e-17 62.9 0.8 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS PF01380.22 GAM35481.1 - 0.048 13.5 0.5 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 SIS domain SIS_2 PF13580.6 GAM35481.1 - 0.053 13.6 0.0 0.41 10.7 0.0 2.4 1 1 0 1 1 1 0 SIS domain MFS_1 PF07690.16 GAM35482.1 - 4.5e-12 45.6 39.2 7.8e-12 44.8 39.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAM35482.1 - 3.6e-10 39.8 3.8 3.6e-10 39.8 3.8 2.8 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 LapA_dom PF06305.11 GAM35482.1 - 0.085 12.7 0.1 0.085 12.7 0.1 3.9 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain COesterase PF00135.28 GAM35483.1 - 3.4e-120 402.3 0.0 6.8e-120 401.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM35483.1 - 1.8e-06 27.9 0.8 0.0037 17.2 0.1 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM35483.1 - 1.6e-05 24.5 0.0 3.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family MFS_1 PF07690.16 GAM35484.1 - 2.7e-14 52.9 7.5 3.5e-14 52.5 7.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM35484.1 - 1.7e-09 37.0 0.0 1.9e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Neurensin PF14927.6 GAM35484.1 - 1.3 8.8 3.9 3.2 7.5 3.8 1.7 1 1 0 1 1 1 0 Neurensin MFS_1 PF07690.16 GAM35485.1 - 2.4e-16 59.6 9.9 2.4e-16 59.6 9.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TctB PF07331.11 GAM35485.1 - 2.8 8.2 15.4 0.21 11.8 4.7 3.2 2 1 2 4 4 4 0 Tripartite tricarboxylate transporter TctB family Zn_clus PF00172.18 GAM35486.1 - 7.6e-12 45.1 11.5 1.7e-11 44.1 11.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM35486.1 - 6.5e-09 35.2 1.2 1.3e-08 34.2 1.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_75 PF07335.11 GAM35487.1 - 3.6e-62 209.5 0.3 4.4e-62 209.2 0.3 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 PALP PF00291.25 GAM35487.1 - 0.093 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Polysacc_deac_1 PF01522.21 GAM35488.1 - 1.3e-18 67.1 0.0 3.8e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 GAM35488.1 - 1.6e-07 31.2 0.0 3.5e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) adh_short PF00106.25 GAM35488.1 - 2.2e-06 27.3 0.0 8.1e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35488.1 - 0.00023 20.8 0.0 0.0013 18.3 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAM35488.1 - 0.00067 19.2 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AAA_2 PF07724.14 GAM35489.1 - 7.6e-46 156.3 0.0 2.2e-44 151.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAM35489.1 - 2.9e-33 113.9 1.1 2.9e-33 113.9 1.1 4.1 4 0 0 4 4 4 1 AAA lid domain AAA PF00004.29 GAM35489.1 - 3.7e-26 92.1 0.0 4.1e-14 53.1 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GAM35489.1 - 6.2e-24 83.9 3.3 6.3e-24 83.9 0.6 2.6 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GAM35489.1 - 2e-15 57.0 0.1 5.5e-09 36.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAM35489.1 - 5e-14 52.7 0.1 5.5e-05 23.5 0.0 4.6 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 GAM35489.1 - 2.3e-12 47.6 7.8 1.9e-06 28.3 0.0 5.1 5 1 1 6 6 4 2 AAA ATPase domain Sigma54_activat PF00158.26 GAM35489.1 - 3.3e-09 36.7 0.0 2.7e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.6 GAM35489.1 - 1.2e-06 29.1 0.1 0.038 14.5 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_7 PF12775.7 GAM35489.1 - 4e-06 26.5 0.0 0.014 14.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 GAM35489.1 - 4e-06 26.9 0.0 0.11 12.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 GAM35489.1 - 5.9e-06 26.1 0.0 0.073 12.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 GAM35489.1 - 1.9e-05 24.9 0.0 0.27 11.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 GAM35489.1 - 2.2e-05 24.0 0.0 0.18 11.2 0.0 3.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 GAM35489.1 - 2.2e-05 23.9 1.3 0.35 10.3 0.0 4.7 4 2 1 5 5 4 1 Bacterial TniB protein RNA_helicase PF00910.22 GAM35489.1 - 7.6e-05 23.1 0.0 0.56 10.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 GAM35489.1 - 8.6e-05 22.6 3.4 0.13 12.2 0.2 4.1 4 1 0 4 4 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 GAM35489.1 - 0.0001 22.1 0.0 0.64 9.7 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 GAM35489.1 - 0.00011 22.5 2.9 0.56 10.4 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 GAM35489.1 - 0.00021 21.9 7.0 0.37 11.3 0.0 3.9 4 0 0 4 4 3 1 AAA domain RsgA_GTPase PF03193.16 GAM35489.1 - 0.00025 21.0 0.1 0.69 9.8 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase ABC_tran PF00005.27 GAM35489.1 - 0.00028 21.4 0.4 0.56 10.7 0.0 3.3 3 0 0 3 3 2 1 ABC transporter TsaE PF02367.17 GAM35489.1 - 0.00032 20.7 0.0 0.4 10.7 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 GAM35489.1 - 0.00033 20.5 0.0 1.1 9.1 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAM35489.1 - 0.00039 20.2 1.9 4.7 6.9 0.9 4.4 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 GAM35489.1 - 0.00065 18.9 0.6 0.013 14.5 0.0 2.7 2 1 0 2 2 2 1 Type II/IV secretion system protein Clp_N PF02861.20 GAM35489.1 - 0.00071 19.7 0.7 0.42 10.8 0.0 3.9 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component Torsin PF06309.11 GAM35489.1 - 0.00078 19.5 0.0 0.0059 16.7 0.0 2.2 3 0 0 3 3 2 1 Torsin AAA_24 PF13479.6 GAM35489.1 - 0.00087 19.1 0.0 0.79 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAM35489.1 - 0.00092 19.6 0.1 0.38 11.1 0.1 3.3 2 1 1 3 3 2 1 AAA domain AAA_29 PF13555.6 GAM35489.1 - 0.0027 17.4 0.0 3 7.7 0.0 2.7 3 0 0 3 3 2 1 P-loop containing region of AAA domain NACHT PF05729.12 GAM35489.1 - 0.0057 16.6 0.1 0.49 10.3 0.0 2.8 3 0 0 3 3 2 1 NACHT domain ResIII PF04851.15 GAM35489.1 - 0.0082 16.2 0.0 1.2 9.1 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Roc PF08477.13 GAM35489.1 - 0.012 15.9 0.0 3.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 GAM35489.1 - 0.013 15.4 0.0 0.25 11.2 0.0 2.7 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 GAM35489.1 - 0.018 14.3 0.0 1.4 8.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 GAM35489.1 - 0.018 14.6 4.1 0.44 10.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain Rad17 PF03215.15 GAM35489.1 - 0.019 14.9 0.0 6.2 6.7 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 GAM35489.1 - 0.032 13.8 0.0 5.9 6.5 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MPS2 PF17060.5 GAM35489.1 - 0.087 12.1 2.7 0.16 11.2 2.7 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 BPL_N PF09825.9 GAM35489.1 - 0.31 10.1 0.9 0.69 8.9 0.9 1.5 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal V_ATPase_I PF01496.19 GAM35489.1 - 0.35 8.7 2.0 0.52 8.2 2.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 GAM35489.1 - 0.41 9.2 4.5 0.68 8.4 4.5 1.3 1 0 0 1 1 1 0 Macoilin family Spc7 PF08317.11 GAM35489.1 - 0.68 8.8 10.4 1.8 7.4 10.4 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein YlqD PF11068.8 GAM35489.1 - 5.3 7.4 12.0 0.2 12.0 4.4 2.6 3 0 0 3 3 1 0 YlqD protein Sulfotransfer_3 PF13469.6 GAM35490.1 - 0.015 15.7 0.0 10 6.5 0.0 3.2 2 1 0 2 2 2 0 Sulfotransferase family ATG27 PF09451.10 GAM35491.1 - 3.4e-87 292.7 0.0 4.1e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 GAM35491.1 - 0.0075 16.3 0.1 0.72 9.9 0.1 2.6 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat Prefoldin_2 PF01920.20 GAM35492.1 - 3.4e-23 81.6 2.0 4.3e-23 81.3 2.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit PEP-utilisers_N PF05524.13 GAM35492.1 - 0.0083 16.3 3.1 0.01 16.0 0.1 2.3 1 1 1 2 2 2 1 PEP-utilising enzyme, N-terminal FTA4 PF13093.6 GAM35492.1 - 0.037 13.9 3.2 0.046 13.6 3.2 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 eIF-4B PF06273.11 GAM35492.1 - 0.39 9.7 3.8 0.43 9.6 3.8 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DivIC PF04977.15 GAM35492.1 - 1.3 8.8 8.1 2.9 7.7 4.0 2.3 2 0 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 GAM35492.1 - 2.4 8.7 13.1 13 6.3 0.1 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Fungal_trans PF04082.18 GAM35493.1 - 5.2e-24 84.7 0.1 8.5e-24 84.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM35493.1 - 3.3e-05 23.9 15.4 0.0001 22.3 15.4 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 GAM35494.1 - 3.4e-108 362.4 19.1 3.8e-108 362.2 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM35494.1 - 8.9e-15 54.5 32.0 2.5e-12 46.4 11.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_1 PF04531.13 GAM35494.1 - 0.49 11.0 4.3 0.65 10.6 0.0 3.1 3 1 0 3 3 3 0 Bacteriophage holin COesterase PF00135.28 GAM35495.1 - 2.4e-60 204.9 0.0 3.1e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM35495.1 - 1.8e-06 27.9 1.2 0.0024 17.7 0.3 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Fungal_trans PF04082.18 GAM35496.1 - 7.5e-16 57.9 0.1 1.5e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 GAM35497.1 - 9.3e-27 93.7 0.2 1.6e-26 92.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain UNC-93 PF05978.16 GAM35498.1 - 1.7e-14 53.8 8.6 1.7e-14 53.8 8.6 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 GAM35498.1 - 6.7e-12 45.0 37.8 6.7e-12 45.0 37.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.6 GAM35498.1 - 0.037 14.5 1.0 0.099 13.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF5134 PF17197.4 GAM35498.1 - 0.62 10.0 6.4 0.15 12.0 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) GFO_IDH_MocA_C PF02894.17 GAM35499.1 - 2.6e-06 27.4 0.0 5.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 GAM35499.1 - 0.11 13.3 0.0 0.19 12.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold FAD_binding_3 PF01494.19 GAM35500.1 - 1e-19 71.0 0.1 3.6e-19 69.2 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.11 GAM35500.1 - 5.7e-14 52.3 0.0 9.4e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.6 GAM35500.1 - 3.5e-07 30.4 0.1 7.6e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM35500.1 - 1.2e-06 27.9 1.6 3.5e-06 26.4 0.7 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM35500.1 - 7.4e-06 25.4 1.1 3.2e-05 23.3 1.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM35500.1 - 9.5e-06 25.4 0.3 0.0031 17.2 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 GAM35500.1 - 0.00015 20.9 0.1 0.00022 20.4 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAM35500.1 - 0.00044 19.7 0.3 0.0007 19.1 0.3 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM35500.1 - 0.0016 17.3 0.9 0.0069 15.1 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 GAM35500.1 - 0.0028 16.8 0.1 0.0055 15.8 0.1 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 GAM35500.1 - 0.0077 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 GAM35500.1 - 0.01 15.2 0.2 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 GAM35500.1 - 0.014 15.9 0.6 0.033 14.7 0.2 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM35500.1 - 0.023 13.9 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 GAM35500.1 - 0.024 13.9 0.6 0.22 10.7 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM35500.1 - 0.04 12.8 0.1 0.077 11.8 0.1 1.4 1 1 0 1 1 1 0 Tryptophan halogenase Thaumatin PF00314.17 GAM35502.1 - 5.6e-67 225.5 0.9 9e-67 224.8 0.9 1.3 1 1 0 1 1 1 1 Thaumatin family 4HBT_3 PF13622.6 GAM35503.1 - 9e-82 275.0 0.0 1.1e-81 274.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 GAM35503.1 - 8e-25 87.2 0.0 2.6e-11 43.5 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase GFA PF04828.14 GAM35504.1 - 5.5e-22 77.9 0.4 1e-21 77.0 0.4 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Fungal_trans PF04082.18 GAM35504.1 - 2.1e-10 40.1 0.4 7.1e-10 38.4 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Arrestin_C PF02752.22 GAM35505.1 - 1e-06 29.2 0.3 1.8e-06 28.4 0.1 1.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain His_Phos_2 PF00328.22 GAM35506.1 - 0.0013 18.1 0.0 0.032 13.6 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) PI-PLC-X PF00388.19 GAM35507.1 - 6e-06 25.9 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Pro_dh PF01619.18 GAM35508.1 - 5e-59 200.2 1.3 5.7e-59 200.1 1.3 1.0 1 0 0 1 1 1 1 Proline dehydrogenase ARTD15_N PF18084.1 GAM35508.1 - 0.047 14.0 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 ARTD15 N-terminal domain MFS_1 PF07690.16 GAM35509.1 - 4e-29 101.6 39.3 4e-29 101.6 39.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM35509.1 - 3.9e-07 29.3 13.1 3.9e-07 29.3 13.1 2.1 2 1 1 3 3 3 1 Sugar (and other) transporter Abhydrolase_3 PF07859.13 GAM35512.1 - 5.5e-33 114.6 0.0 1.5e-32 113.2 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pirin PF02678.16 GAM35512.1 - 1e-26 93.0 0.7 2.5e-26 91.8 0.7 1.6 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 GAM35512.1 - 2.9e-05 23.7 2.5 0.0012 18.5 0.4 3.0 2 1 0 2 2 2 1 Cupin domain COesterase PF00135.28 GAM35512.1 - 0.0019 17.2 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Thioesterase PF00975.20 GAM35512.1 - 0.026 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Fungal_trans_2 PF11951.8 GAM35513.1 - 1.1e-07 31.0 0.8 1.4e-07 30.7 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 GAM35514.1 - 8e-23 81.1 7.9 1.1e-22 80.7 7.9 1.1 1 0 0 1 1 1 1 RTA1 like protein p450 PF00067.22 GAM35515.1 - 6.6e-72 242.7 0.0 8.6e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.11 GAM35515.1 - 1e-05 25.2 0.0 2.5e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Glyco_hydro_71 PF03659.14 GAM35516.1 - 1.2e-126 422.5 8.5 1.5e-126 422.3 8.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Fungal_trans PF04082.18 GAM35517.1 - 2.6e-21 75.9 0.0 4.8e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM35517.1 - 0.00088 19.4 8.3 0.0016 18.5 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Npa1 PF11707.8 GAM35519.1 - 1.3e-94 317.4 0.8 8.8e-94 314.6 0.1 2.3 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 GAM35519.1 - 4.7e-60 202.6 0.5 6.9e-59 198.8 0.1 2.8 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Creb_binding PF09030.10 GAM35519.1 - 0.13 12.9 0.0 0.54 11.0 0.0 2.0 1 0 0 1 1 1 0 Creb binding HA2 PF04408.23 GAM35520.1 - 8.2e-25 87.2 0.1 8.2e-25 87.2 0.1 2.4 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAM35520.1 - 1.7e-18 66.7 0.0 3.6e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAM35520.1 - 4.4e-14 52.8 0.0 1.1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 GAM35520.1 - 5.7e-10 39.4 1.8 1.2e-09 38.3 0.8 2.0 2 0 0 2 2 2 1 S1 RNA binding domain DEAD PF00270.29 GAM35520.1 - 3.2e-05 23.8 0.0 7.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAM35520.1 - 0.00065 20.0 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAM35520.1 - 0.0019 17.3 0.0 0.0042 16.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 GAM35520.1 - 0.0086 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 GAM35520.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 GAM35520.1 - 0.028 13.8 0.0 0.4 10.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 GAM35520.1 - 0.029 14.8 0.0 0.092 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 GAM35520.1 - 0.14 12.1 0.4 3.2 7.7 0.0 2.7 3 0 0 3 3 3 0 Microtubule binding AAA_19 PF13245.6 GAM35520.1 - 0.14 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAM35520.1 - 0.18 12.3 0.7 0.81 10.2 0.1 2.4 2 1 1 3 3 3 0 ABC transporter CAF20 PF17052.5 GAM35520.1 - 8.5 6.5 11.3 28 4.9 11.3 1.8 1 0 0 1 1 1 0 Cap associated factor G-patch PF01585.23 GAM35521.1 - 0.0016 18.3 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAM35521.1 - 0.056 13.5 0.1 0.16 12.1 0.1 1.8 1 0 0 1 1 1 0 G-patch domain Sec1 PF00995.23 GAM35522.1 - 3.1e-123 413.0 0.0 3.7e-123 412.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SUV3_C PF12513.8 GAM35523.1 - 8.4e-19 67.2 0.5 2.2e-18 65.9 0.5 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 GAM35523.1 - 2.1e-11 44.1 0.1 5.1e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 GAM35523.1 - 0.00021 21.1 0.1 0.0005 19.9 0.1 1.7 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 DUF4771 PF15995.5 GAM35523.1 - 0.038 14.3 0.1 0.079 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) TK PF00265.18 GAM35523.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase adh_short PF00106.25 GAM35524.1 - 1.6e-11 44.1 0.0 3.4e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35524.1 - 3.9e-05 23.3 0.0 0.02 14.4 0.0 2.3 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM35524.1 - 4.9e-05 23.3 0.0 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 KR domain TMP_2 PF06791.13 GAM35524.1 - 0.1 12.3 0.1 0.1 12.3 0.1 1.6 2 0 0 2 2 2 0 Prophage tail length tape measure protein GDP_Man_Dehyd PF16363.5 GAM35525.1 - 1.3e-49 169.4 0.0 3.3e-49 168.1 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAM35525.1 - 6.9e-47 159.9 0.0 9.4e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM35525.1 - 3.5e-15 55.7 0.0 9.4e-15 54.4 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAM35525.1 - 8.7e-12 44.7 0.0 1.3e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAM35525.1 - 1.3e-11 44.2 0.0 1e-10 41.3 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 GAM35525.1 - 1.2e-09 37.9 0.0 2.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM35525.1 - 3e-08 33.8 0.0 5.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAM35525.1 - 6.3e-05 22.9 0.0 9.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 GAM35525.1 - 6.8e-05 22.5 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 GAM35525.1 - 0.00051 19.3 0.2 0.012 14.8 0.2 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 GAM35525.1 - 0.016 14.8 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 GAM35525.1 - 0.084 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PAT1 PF09770.9 GAM35526.1 - 0 1153.7 10.7 0 1152.2 10.7 1.6 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Erf4 PF10256.9 GAM35526.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Glyco_transf_15 PF01793.16 GAM35527.1 - 1.1e-132 442.2 7.0 1.4e-132 441.9 7.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF2788 PF10981.8 GAM35527.1 - 0.05 13.6 0.2 0.079 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2788) Glyco_hydro_72 PF03198.14 GAM35528.1 - 7.5e-82 275.1 0.6 1e-81 274.7 0.6 1.2 1 0 0 1 1 1 1 Glucanosyltransferase SKG6 PF08693.10 GAM35528.1 - 0.00018 20.9 0.6 0.00043 19.6 0.6 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 GAM35528.1 - 0.0058 15.5 0.4 0.012 14.5 0.4 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 GAM35528.1 - 0.012 15.7 0.4 0.024 14.8 0.4 1.4 1 0 0 1 1 1 0 Podoplanin Adaptin_N PF01602.20 GAM35529.1 - 1.4e-71 241.6 0.1 3.6e-71 240.3 0.1 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAM35529.1 - 2.1e-05 24.6 0.6 0.0057 16.7 0.0 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM35529.1 - 0.00016 22.0 2.2 0.38 11.2 0.0 3.0 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 GAM35529.1 - 0.00049 20.1 1.4 21 5.7 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat AbiEi_3 PF11459.8 GAM35529.1 - 0.13 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system TPR_14 PF13428.6 GAM35530.1 - 1.2e-10 41.3 2.0 0.00011 22.7 0.3 4.9 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM35530.1 - 5.3e-09 35.9 0.5 5e-05 23.4 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM35530.1 - 6.5e-08 33.0 2.1 5.8e-06 26.7 0.1 3.2 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM35530.1 - 8.5e-08 31.7 0.0 0.0011 18.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM35530.1 - 1.6e-07 31.0 0.1 0.00021 21.2 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM35530.1 - 1.7e-07 30.8 0.4 0.0018 18.2 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAM35530.1 - 4.2e-07 29.6 0.1 0.02 14.6 0.0 3.9 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.6 GAM35530.1 - 0.0019 18.8 0.2 0.0019 18.8 0.2 2.6 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM35530.1 - 0.0021 18.2 0.2 0.0059 16.7 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat MCD_N PF17408.2 GAM35530.1 - 0.0036 17.4 0.1 1.6 8.9 0.0 3.6 3 1 0 3 3 3 1 Malonyl-CoA decarboxylase N-terminal domain TPR_7 PF13176.6 GAM35530.1 - 0.0057 16.6 0.1 1.8 8.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM35530.1 - 0.01 16.1 6.8 0.6 10.4 0.9 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 GAM35530.1 - 0.032 13.5 0.9 0.059 12.6 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAM35530.1 - 0.035 14.4 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TAF1_subA PF14929.6 GAM35530.1 - 0.038 13.4 0.1 0.069 12.6 0.1 1.5 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A SUKH-4 PF14435.6 GAM35530.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 SUKH-4 immunity protein TPR_6 PF13174.6 GAM35530.1 - 0.48 11.2 2.9 14 6.6 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPH PF13868.6 GAM35531.1 - 3.7 6.0 54.4 6.4 5.2 54.4 1.3 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain GAGA_bind PF06217.12 GAM35531.1 - 6.1 7.0 14.1 16 5.6 14.1 1.7 1 0 0 1 1 1 0 GAGA binding protein-like family CENP-Q PF13094.6 GAM35532.1 - 0.0016 18.7 5.0 0.017 15.3 1.7 2.4 2 0 0 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit GPS2_interact PF15784.5 GAM35532.1 - 0.025 15.0 2.2 0.08 13.4 2.4 1.7 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain HrpB7 PF09486.10 GAM35532.1 - 0.11 12.9 1.6 0.43 11.0 0.1 2.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Aldedh PF00171.22 GAM35533.1 - 5e-11 41.8 11.3 4.8e-10 38.5 6.9 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAM35533.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Ribosomal_L18 PF17135.4 GAM35534.1 - 3e-95 317.0 4.1 3.9e-95 316.6 4.1 1.2 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Mito_carr PF00153.27 GAM35534.1 - 3.9e-62 206.2 0.6 5e-22 77.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L27A PF00828.19 GAM35534.1 - 0.00031 21.4 0.1 0.00098 19.8 0.1 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Serine_protease PF18405.1 GAM35534.1 - 0.00048 19.4 0.2 0.05 12.8 0.0 2.7 1 1 2 3 3 3 2 Gammaproteobacterial serine protease RRM_1 PF00076.22 GAM35535.1 - 3.3e-12 46.0 0.0 4.6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM35535.1 - 0.00086 19.3 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CH PF00307.31 GAM35536.1 - 2.4e-75 249.7 0.0 5.3e-21 74.8 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 GAM35536.1 - 3.1e-06 27.5 2.0 3.8e-05 24.1 0.4 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 GAM35536.1 - 0.00039 19.8 2.6 1.1 8.9 0.2 3.7 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.8 GAM35536.1 - 0.0006 19.6 0.0 0.42 10.5 0.0 3.5 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_6 PF13405.6 GAM35536.1 - 0.017 15.0 3.9 0.4 10.7 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain Ank_2 PF12796.7 GAM35537.1 - 5.4e-91 299.3 8.2 1e-15 58.1 0.0 10.4 3 3 7 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM35537.1 - 1.6e-75 248.6 28.7 8.5e-10 39.0 0.0 14.2 3 2 14 17 17 17 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM35537.1 - 1.8e-56 181.5 20.6 0.002 18.5 0.0 19.7 20 1 1 21 21 21 13 Ankyrin repeat Ank PF00023.30 GAM35537.1 - 1.8e-47 157.8 28.7 0.0048 17.3 0.0 18.2 17 2 1 18 18 18 12 Ankyrin repeat Ank_5 PF13857.6 GAM35537.1 - 1.2e-33 114.7 20.6 2.7e-06 27.5 0.0 15.1 3 3 16 19 19 19 10 Ankyrin repeats (many copies) Clr5 PF14420.6 GAM35537.1 - 1e-12 48.1 2.7 1.8e-12 47.3 2.7 1.4 1 0 0 1 1 1 1 Clr5 domain AAA_lid_3 PF17862.1 GAM35537.1 - 0.038 13.8 0.5 0.16 11.8 0.5 2.0 1 0 0 1 1 1 0 AAA+ lid domain Toprim_3 PF13362.6 GAM35537.1 - 0.05 14.0 1.4 0.75 10.2 0.0 3.3 3 0 0 3 3 3 0 Toprim domain PXA PF02194.15 GAM35538.1 - 5.9e-33 114.4 0.1 1.2e-32 113.4 0.1 1.6 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 GAM35538.1 - 2.9e-21 76.1 0.6 6e-20 71.9 0.1 2.7 2 0 0 2 2 2 1 Sorting nexin C terminal 4HBT PF03061.22 GAM35538.1 - 2.5e-10 40.6 0.0 5.8e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily PX PF00787.24 GAM35538.1 - 3.2e-08 33.5 0.3 1.2e-07 31.7 0.1 2.1 2 0 0 2 2 2 1 PX domain PC4 PF02229.16 GAM35539.1 - 3.2e-24 84.3 0.0 7.7e-24 83.1 0.1 1.6 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) Big_1 PF02369.16 GAM35539.1 - 0.0056 16.7 2.1 0.0088 16.0 2.1 1.3 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) CPSF100_C PF13299.6 GAM35539.1 - 1.8 8.7 6.9 0.68 10.1 1.4 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 GAM35539.1 - 2.4 6.8 5.4 2.7 6.7 5.4 1.1 1 0 0 1 1 1 0 Presenilin Hydantoinase_B PF02538.14 GAM35540.1 - 2.9e-223 742.0 0.0 3.8e-223 741.6 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 GAM35540.1 - 1.7e-104 349.2 0.1 3.8e-104 348.0 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GAM35540.1 - 1.9e-62 210.1 0.5 1.4e-60 204.1 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Creatininase PF02633.14 GAM35540.1 - 0.03 13.8 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Creatinine amidohydrolase ZYG-11_interact PF05884.12 GAM35540.1 - 0.042 13.3 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 MIT PF04212.18 GAM35541.1 - 1.1e-12 47.9 2.3 2.3e-12 46.8 2.3 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain MukE PF04288.13 GAM35541.1 - 0.021 13.8 0.0 0.021 13.8 0.0 1.6 2 0 0 2 2 2 0 MukE-like family ELH PF02323.15 GAM35541.1 - 4 6.7 15.3 0.024 14.0 3.5 2.5 2 0 0 2 2 2 0 Egg-laying hormone precursor DUF3027 PF11228.8 GAM35542.1 - 0.3 11.1 1.8 0.62 10.0 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) Peptidase_M24 PF00557.24 GAM35543.1 - 6.1e-55 186.1 0.1 8.2e-55 185.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 GAM35543.1 - 7.7e-26 90.2 0.0 2.2e-25 88.8 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Peptidase_M1 PF01433.20 GAM35544.1 - 2e-45 155.0 0.4 3e-45 154.5 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 GAM35544.1 - 2.3e-34 117.8 0.0 5.5e-34 116.6 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 GAM35544.1 - 1.8e-29 103.2 0.0 2.8e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain COX5A PF02284.16 GAM35544.1 - 0.0083 16.1 0.1 0.018 15.0 0.1 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Peptidase_MA_2 PF13485.6 GAM35544.1 - 0.057 13.1 0.1 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 GAM35544.1 - 1.7 9.0 5.5 5.1 7.5 2.9 2.6 2 1 0 2 2 2 0 M61 glycyl aminopeptidase TIP41 PF04176.13 GAM35545.1 - 8e-70 233.8 0.0 1.5e-69 232.9 0.0 1.4 1 0 0 1 1 1 1 TIP41-like family Ubiq_cyt_C_chap PF03981.12 GAM35545.1 - 1.1e-35 122.8 0.1 2.1e-35 121.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Pkinase PF00069.25 GAM35546.1 - 5.9e-73 245.5 0.0 7.6e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM35546.1 - 7.4e-44 150.0 0.0 9.8e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM35546.1 - 2.7e-07 30.2 0.0 1.5e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAM35546.1 - 0.00027 20.3 0.2 0.00048 19.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAM35546.1 - 0.0045 16.0 0.1 0.0069 15.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 GAM35546.1 - 0.02 14.5 0.0 0.061 12.9 0.0 1.6 1 1 1 2 2 2 0 RIO1 family FTA2 PF13095.6 GAM35546.1 - 0.039 13.6 0.1 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 GAM35546.1 - 0.041 13.4 0.1 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 GAM35546.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.9 GAM35547.1 - 1.4e-21 77.0 0.0 2e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase M76 family HNH_5 PF14279.6 GAM35547.1 - 0.02 14.7 1.4 0.12 12.2 0.2 2.3 2 0 0 2 2 2 0 HNH endonuclease AA_kinase PF00696.28 GAM35548.1 - 1.2e-41 142.9 0.7 1.6e-41 142.5 0.7 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 GAM35548.1 - 6.4e-14 51.7 0.1 2.8e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 PUA domain GPI-anchored PF10342.9 GAM35549.1 - 2.7e-14 53.7 0.0 5.9e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.11 GAM35549.1 - 4.8e-13 49.7 3.3 4.8e-13 49.7 3.3 1.9 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 SRPRB PF09439.10 GAM35550.1 - 8.5e-24 84.0 0.3 2.7e-22 79.1 0.3 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAM35550.1 - 2.7e-05 24.2 0.0 4.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 GAM35550.1 - 3.7e-05 23.5 0.1 0.00077 19.1 0.1 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 GAM35550.1 - 0.0017 18.8 0.1 0.0042 17.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Arf PF00025.21 GAM35550.1 - 0.027 13.9 0.1 0.35 10.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family BatA PF07584.11 GAM35550.1 - 0.053 13.9 0.6 0.13 12.6 0.6 1.7 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal AAA_5 PF07728.14 GAM35550.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.12 GAM35550.1 - 0.23 10.9 0.1 0.4 10.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 GAM35550.1 - 0.23 11.3 2.0 0.46 10.4 0.8 2.0 2 0 0 2 2 2 0 RsgA GTPase PALP PF00291.25 GAM35551.1 - 5.2e-67 226.3 0.2 7e-67 225.9 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 GAM35551.1 - 1.3e-11 44.8 0.0 5.3e-09 36.4 0.0 2.9 2 0 0 2 2 2 2 CBS domain GHMP_kinases_C PF08544.13 GAM35551.1 - 0.13 12.6 0.1 17 5.9 0.0 2.6 2 0 0 2 2 2 0 GHMP kinases C terminal DUF5496 PF17600.2 GAM35551.1 - 0.19 11.8 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5496) GerPC PF10737.9 GAM35552.1 - 0.21 11.7 9.7 0.16 12.0 0.8 3.2 3 0 0 3 3 3 0 Spore germination protein GerPC DUF1117 PF06547.12 GAM35552.1 - 0.78 10.3 3.5 5.9 7.5 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1117) Cyclin PF08613.11 GAM35554.1 - 1e-39 136.5 0.0 1.3e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAM35554.1 - 0.024 14.4 0.1 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Ank_2 PF12796.7 GAM35555.1 - 2.4e-34 117.8 0.0 2.4e-12 47.3 0.0 3.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) DHHC PF01529.20 GAM35555.1 - 1e-33 116.3 15.2 1e-33 116.3 15.2 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 GAM35555.1 - 1.6e-23 82.5 1.0 5.1e-06 26.7 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM35555.1 - 3.9e-22 76.0 3.2 4.4e-07 29.7 0.0 6.1 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 GAM35555.1 - 1.1e-20 73.1 1.1 3.8e-06 27.1 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 GAM35555.1 - 2.1e-16 60.1 1.3 0.00015 22.3 0.0 4.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) K_oxygenase PF13434.6 GAM35556.1 - 1.6e-93 313.6 0.0 2.6e-91 306.3 0.0 2.0 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 GAM35556.1 - 4e-06 26.3 0.0 4.8e-05 22.7 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM35556.1 - 0.00078 18.8 0.1 0.048 12.9 0.0 2.8 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM35556.1 - 0.0019 18.2 0.0 0.23 11.4 0.0 3.6 4 1 0 5 5 5 1 FAD-NAD(P)-binding DUF3990 PF13151.6 GAM35556.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) DUF2183 PF09949.9 GAM35556.1 - 0.07 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) AMP-binding PF00501.28 GAM35557.1 - 4e-227 753.8 0.0 5.4e-80 269.0 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 GAM35557.1 - 5.3e-197 655.0 2.1 4.4e-42 144.3 1.6 7.2 7 1 0 7 7 7 6 Condensation domain PP-binding PF00550.25 GAM35557.1 - 8.4e-59 195.8 12.3 1.5e-11 44.5 0.1 7.2 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAM35557.1 - 1.7e-15 57.7 0.0 0.00042 21.3 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 GAM35558.1 - 3e-44 151.3 0.0 9.7e-42 143.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM35558.1 - 1.3e-25 90.2 0.0 3e-25 89.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase OB_NTP_bind PF07717.16 GAM35559.1 - 2.2e-22 79.2 0.0 5e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 GAM35559.1 - 1.2e-19 70.6 0.0 1.2e-19 70.6 0.0 4.4 4 1 0 4 4 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAM35559.1 - 1.1e-12 48.2 0.0 2.5e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM35559.1 - 8.7e-09 35.4 0.1 1.9e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAM35559.1 - 8.2e-06 26.1 0.5 2.7e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAM35559.1 - 3.7e-05 23.5 0.0 7.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM35559.1 - 0.00018 21.9 0.1 0.00038 20.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAM35559.1 - 0.00072 18.7 0.0 0.0016 17.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 GAM35559.1 - 0.002 17.8 0.2 0.0061 16.2 0.2 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 GAM35559.1 - 0.0076 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain ABC_tran PF00005.27 GAM35559.1 - 0.06 13.9 0.3 0.39 11.2 0.1 2.5 1 1 1 2 2 2 0 ABC transporter ResIII PF04851.15 GAM35559.1 - 0.063 13.3 0.7 2.7 8.0 0.1 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 GAM35559.1 - 0.12 12.8 0.0 0.12 12.8 0.0 3.8 2 1 1 3 3 1 0 AAA domain Cyt-b5 PF00173.28 GAM35560.1 - 4.3e-22 78.0 0.1 4.8e-22 77.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 GAM35560.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 V-ATPase subunit H Zip PF02535.22 GAM35561.1 - 6.9e-60 203.0 0.1 8.1e-60 202.8 0.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Sdh_cyt PF01127.22 GAM35561.1 - 0.52 10.4 3.5 4.1 7.5 0.1 2.9 2 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Acetyltransf_1 PF00583.25 GAM35562.1 - 2.7e-10 40.5 0.0 6e-10 39.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM35562.1 - 4.2e-08 33.2 0.0 1.2e-07 31.8 0.0 1.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM35562.1 - 4.2e-06 27.1 0.0 8.4e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM35562.1 - 0.00033 20.7 0.0 0.00059 19.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AXE1 PF05448.12 GAM35563.1 - 3.9e-10 38.9 0.0 1.1e-06 27.6 0.0 2.5 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 GAM35563.1 - 1e-08 36.1 0.1 1.3e-08 35.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM35563.1 - 4.2e-07 29.5 0.0 9e-07 28.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM35563.1 - 8.8e-06 25.5 0.0 1.9e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 GAM35563.1 - 0.00049 19.8 0.0 0.00073 19.2 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.11 GAM35563.1 - 0.0024 16.8 0.0 0.0049 15.7 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) PAF-AH_p_II PF03403.13 GAM35563.1 - 0.017 13.6 0.0 0.52 8.8 0.0 2.2 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II BAAT_C PF08840.11 GAM35563.1 - 0.048 13.6 0.0 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 GAM35563.1 - 0.049 13.1 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family adh_short_C2 PF13561.6 GAM35564.1 - 1.6e-56 191.5 1.8 1.8e-56 191.3 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM35564.1 - 3.6e-47 160.4 1.7 4.4e-47 160.1 1.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM35564.1 - 2.2e-13 50.5 1.3 3.2e-13 50.0 1.3 1.1 1 0 0 1 1 1 1 KR domain B12-binding PF02310.19 GAM35564.1 - 0.021 14.9 0.3 7.6 6.6 0.1 2.7 2 1 1 3 3 3 0 B12 binding domain Eno-Rase_NADH_b PF12242.8 GAM35564.1 - 0.077 12.8 0.7 0.44 10.3 0.3 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RNA_pol_Rpb1_4 PF05000.17 GAM35564.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 DUF3425 PF11905.8 GAM35565.1 - 2e-14 53.6 0.7 1.6e-13 50.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Mcp5_PH PF12814.7 GAM35566.1 - 2.9e-46 156.5 0.0 5.5e-46 155.7 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 GAM35566.1 - 1.1e-07 32.6 14.8 2.1e-07 31.6 14.8 1.5 1 0 0 1 1 1 1 Fez1 TPR_MLP1_2 PF07926.12 GAM35566.1 - 6.2e-05 23.1 18.6 0.017 15.2 9.3 2.4 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein DUF4482 PF14818.6 GAM35566.1 - 0.00026 21.8 0.5 0.00026 21.8 0.5 3.7 2 1 1 3 3 2 1 Domain of unknown function (DUF4482) ADIP PF11559.8 GAM35566.1 - 0.003 17.7 2.8 0.003 17.7 2.8 2.4 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 GAM35566.1 - 0.015 15.1 7.1 0.031 14.1 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Cnn_1N PF07989.11 GAM35566.1 - 0.029 14.5 11.5 0.15 12.2 7.0 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 ERM PF00769.19 GAM35566.1 - 0.19 11.5 21.7 15 5.3 21.7 2.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Golgin_A5 PF09787.9 GAM35566.1 - 0.3 10.5 16.6 0.54 9.7 16.6 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 GAS PF13851.6 GAM35566.1 - 0.41 10.0 22.0 1 8.7 22.0 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding MSL1_dimer PF16801.5 GAM35566.1 - 0.54 10.1 4.6 3.1 7.6 0.9 2.4 2 0 0 2 2 2 0 Dimerisation domain of Male-specific-Lethal 1 TACC_C PF05010.14 GAM35566.1 - 0.76 9.5 17.3 2.4 7.9 17.1 1.8 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF641 PF04859.12 GAM35566.1 - 1.4 9.3 7.6 0.26 11.6 0.8 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) CorA PF01544.18 GAM35566.1 - 1.5 8.1 4.1 2.6 7.3 4.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FliJ PF02050.16 GAM35566.1 - 1.7 8.9 11.6 5.2 7.3 11.6 1.9 1 1 0 1 1 1 0 Flagellar FliJ protein HIP1_clath_bdg PF16515.5 GAM35566.1 - 3.3 8.4 14.6 0.17 12.5 4.1 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIC PF04977.15 GAM35566.1 - 5.8 6.8 12.3 0.59 9.9 0.7 3.8 2 1 2 4 4 4 0 Septum formation initiator CENP-F_leu_zip PF10473.9 GAM35566.1 - 6.9 6.7 20.9 7.9 6.5 19.8 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SesA PF17107.5 GAM35567.1 - 1.5e-08 34.8 0.4 1.5e-08 34.8 0.4 2.1 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases ABC_tran PF00005.27 GAM35567.1 - 0.00034 21.1 0.4 0.0092 16.5 0.0 2.8 2 1 0 2 2 2 1 ABC transporter NACHT PF05729.12 GAM35567.1 - 0.003 17.5 1.6 0.0097 15.8 0.0 2.6 2 2 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 GAM35567.1 - 0.012 15.4 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF927 PF06048.11 GAM35567.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) AAA_16 PF13191.6 GAM35567.1 - 0.032 14.6 0.2 0.21 11.9 0.0 2.6 2 2 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 GAM35567.1 - 0.046 14.2 0.5 0.046 14.2 0.5 2.7 2 0 0 2 2 2 0 AAA domain 14-3-3 PF00244.20 GAM35567.1 - 0.05 13.1 2.9 0.087 12.3 2.9 1.3 1 0 0 1 1 1 0 14-3-3 protein AAA_22 PF13401.6 GAM35567.1 - 0.063 13.6 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF3810 PF12725.7 GAM35567.1 - 0.15 11.3 0.1 0.33 10.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF87 PF01935.17 GAM35567.1 - 0.43 10.6 2.2 0.85 9.7 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Flocculin_t3 PF13928.6 GAM35570.1 - 0.064 13.8 5.0 0.064 13.8 5.0 3.6 2 2 1 3 3 3 0 Flocculin type 3 repeat AMP-binding PF00501.28 GAM35571.1 - 3.8e-62 210.3 0.0 9.6e-62 208.9 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM35571.1 - 4.9e-13 49.9 0.0 1.5e-12 48.3 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.18 GAM35572.1 - 1.8e-07 31.3 0.5 2.5e-07 30.9 0.5 1.2 1 0 0 1 1 1 1 BolA-like protein Syntaxin PF00804.25 GAM35573.1 - 7e-12 45.4 13.1 7e-12 45.4 13.1 1.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 GAM35573.1 - 1.5e-11 44.1 3.1 6.8e-11 42.0 3.1 2.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 GAM35573.1 - 0.0038 17.0 13.3 0.022 14.5 13.4 2.0 1 1 0 1 1 1 1 Membrane fusion protein Use1 T7SS_ESX_EspC PF10824.8 GAM35573.1 - 0.034 14.6 9.6 0.5 10.9 0.5 4.0 1 1 2 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm BAR_3 PF16746.5 GAM35573.1 - 0.036 13.8 0.8 0.036 13.8 0.8 2.8 2 1 1 3 3 3 0 BAR domain of APPL family Syntaxin_2 PF14523.6 GAM35573.1 - 0.039 14.3 17.4 0.035 14.5 9.5 2.9 2 2 0 2 2 2 0 Syntaxin-like protein ETRAMP PF09716.10 GAM35573.1 - 0.094 12.8 0.0 0.16 12.1 0.0 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) VitD-bind_III PF09164.10 GAM35573.1 - 0.11 12.5 0.1 0.35 10.9 0.0 1.9 2 0 0 2 2 1 0 Vitamin D binding protein, domain III ApoLp-III PF07464.11 GAM35573.1 - 0.16 12.1 11.3 1.7 8.7 1.8 2.6 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) CD225 PF04505.12 GAM35573.1 - 0.19 11.9 0.7 0.46 10.7 0.7 1.6 1 0 0 1 1 1 0 Interferon-induced transmembrane protein HisKA_3 PF07730.13 GAM35573.1 - 0.33 11.5 0.1 0.33 11.5 0.1 3.9 4 1 1 5 5 4 0 Histidine kinase Prominin PF05478.11 GAM35573.1 - 0.45 8.4 10.9 0.17 9.8 6.7 1.9 1 1 1 2 2 2 0 Prominin DUF3675 PF12428.8 GAM35573.1 - 1.2 9.7 3.5 28 5.3 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3675) TipAS PF07739.13 GAM35573.1 - 1.3 9.5 5.6 7.8 7.1 0.4 2.5 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain Mod_r PF07200.13 GAM35573.1 - 1.7 8.7 13.9 6.2 6.9 5.6 2.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Terminase_2 PF03592.16 GAM35573.1 - 1.7 9.1 8.4 6.5 7.2 8.4 2.0 1 1 0 1 1 1 0 Terminase small subunit Muted PF14942.6 GAM35573.1 - 1.9 8.8 12.6 11 6.3 6.2 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein NPV_P10 PF05531.12 GAM35573.1 - 2.2 8.8 9.6 0.99 9.9 0.3 3.4 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 GAM35573.1 - 6 7.1 14.6 1.3 9.2 2.7 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.11 GAM35573.1 - 6.7 7.3 12.5 0.72 10.5 0.5 3.2 2 1 0 3 3 3 0 Syntaxin 6, N-terminal COG2 PF06148.11 GAM35573.1 - 8.6 6.4 10.4 5.1 7.2 0.2 3.3 3 2 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF148 PF02520.17 GAM35573.1 - 9.1 6.4 15.9 0.39 10.9 2.6 3.0 2 1 0 2 2 2 0 Domain of unknown function DUF148 Fungal_trans PF04082.18 GAM35574.1 - 3.4e-23 82.0 0.5 5.8e-23 81.3 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAPRTase PF04095.16 GAM35575.1 - 1.1e-52 179.1 0.1 3.3e-27 95.7 0.2 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 GAM35575.1 - 4.9e-35 120.6 0.1 8e-35 120.0 0.1 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain ING PF12998.7 GAM35576.1 - 4.4e-24 85.0 4.9 6.9e-24 84.4 4.9 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 GAM35576.1 - 2e-05 24.4 9.2 3.8e-05 23.5 9.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 GAM35576.1 - 0.045 14.0 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain CREPT PF16566.5 GAM35576.1 - 0.097 12.8 2.8 0.24 11.6 2.8 1.6 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour PHD_2 PF13831.6 GAM35576.1 - 0.54 9.9 3.8 1.2 8.8 3.8 1.6 1 0 0 1 1 1 0 PHD-finger RNA_pol_Rpc34 PF05158.12 GAM35577.1 - 8e-100 334.5 0.0 9.1e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit PadR PF03551.14 GAM35577.1 - 0.012 15.5 0.9 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family MarR PF01047.22 GAM35577.1 - 0.07 13.1 0.1 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 MarR family TPR_1 PF00515.28 GAM35578.1 - 3e-43 143.9 22.8 3.7e-06 26.5 0.1 8.9 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 GAM35578.1 - 1.7e-35 118.3 24.1 0.00047 20.1 0.2 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat STI1 PF17830.1 GAM35578.1 - 1.5e-21 76.0 6.2 3.8e-14 52.4 3.9 2.9 2 0 0 2 2 2 2 STI1 domain TPR_8 PF13181.6 GAM35578.1 - 6e-18 63.5 24.7 2.9e-05 23.9 0.3 8.3 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 GAM35578.1 - 6.2e-18 64.9 22.3 2.2e-09 37.5 0.6 6.3 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAM35578.1 - 5.2e-15 54.9 26.0 7.7e-06 25.5 0.8 8.6 5 3 4 9 9 9 4 TPR repeat TPR_16 PF13432.6 GAM35578.1 - 1.1e-13 51.5 15.7 0.0021 18.6 0.0 6.6 5 1 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAM35578.1 - 3.8e-13 49.7 19.4 0.019 15.5 0.2 6.9 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAM35578.1 - 6.8e-12 44.5 11.8 0.00029 20.6 0.1 7.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM35578.1 - 7.5e-11 41.9 20.5 0.022 15.6 0.2 9.3 5 3 5 10 10 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM35578.1 - 4.7e-09 36.3 12.1 0.028 14.6 0.3 6.1 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAM35578.1 - 6.1e-09 35.7 7.8 0.71 10.4 0.1 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAM35578.1 - 1.2e-08 34.6 11.7 0.0015 18.3 0.0 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAM35578.1 - 0.00015 22.1 21.3 0.046 14.4 0.1 7.8 8 0 0 8 8 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM35578.1 - 0.0024 17.9 3.1 54 4.0 0.0 6.2 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 GAM35578.1 - 0.015 15.6 0.5 0.015 15.6 0.5 5.2 4 2 2 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 GAM35578.1 - 0.045 13.8 23.2 5.3 7.2 0.3 6.2 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 GAM35578.1 - 0.086 13.1 13.0 1.7 8.9 0.4 4.6 2 1 3 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Inhibitor_I9 PF05922.16 GAM35578.1 - 0.09 13.5 0.4 0.4 11.4 0.4 2.2 1 0 0 1 1 1 0 Peptidase inhibitor I9 SHNi-TPR PF10516.9 GAM35578.1 - 0.75 9.3 9.5 19 4.8 0.1 5.7 6 0 0 6 6 6 0 SHNi-TPR PspA_IM30 PF04012.12 GAM35578.1 - 0.89 9.1 30.4 0.19 11.3 2.3 3.9 3 1 1 4 4 4 0 PspA/IM30 family DUF627 PF04781.12 GAM35578.1 - 2 8.5 7.9 7.9 6.5 0.7 4.4 3 2 0 4 4 4 0 Protein of unknown function (DUF627) NARP1 PF12569.8 GAM35578.1 - 2 7.2 24.9 0.066 12.1 0.5 4.3 3 2 2 5 5 5 0 NMDA receptor-regulated protein 1 Alkyl_sulf_dimr PF14863.6 GAM35578.1 - 8.6 6.8 8.9 2.2 8.7 0.2 3.7 2 1 0 3 3 3 0 Alkyl sulfatase dimerisation AMP-binding PF00501.28 GAM35579.1 - 1e-76 258.2 0.0 1.2e-76 258.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 GAM35579.1 - 7.9e-16 57.7 0.3 1.9e-15 56.5 0.3 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 GAM35579.1 - 2.8e-14 53.8 0.0 7.6e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 GAM35580.1 - 1.6e-14 53.6 0.0 2.9e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM35580.1 - 1.5e-09 37.8 9.4 2.9e-09 36.9 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 GAM35581.1 - 5.2e-15 55.5 0.0 1.2e-14 54.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GAM35581.1 - 7.3e-07 29.7 0.1 0.0003 21.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM35581.1 - 3.9e-06 26.3 0.1 0.0022 17.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM35581.1 - 0.00034 20.3 0.0 0.0056 16.3 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAM35581.1 - 0.0016 17.9 0.0 0.0032 16.9 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase CoA_transf_3 PF02515.17 GAM35581.1 - 0.0021 17.2 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III NAD_binding_8 PF13450.6 GAM35581.1 - 0.0031 17.7 0.0 0.0079 16.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM35581.1 - 0.0067 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 GAM35581.1 - 0.039 13.2 0.0 0.41 9.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM35581.1 - 0.04 13.0 0.2 0.18 10.9 0.1 1.9 1 1 1 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAM35581.1 - 0.048 12.9 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GAM35581.1 - 0.056 12.7 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 GAM35581.1 - 0.094 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 GAM35581.1 - 0.17 12.3 0.0 0.45 11.0 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding AAA PF00004.29 GAM35582.1 - 1.4e-13 51.4 0.0 2.6e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM35582.1 - 0.00014 22.1 0.2 0.00083 19.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM35582.1 - 0.00061 20.2 0.1 0.0022 18.4 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GAM35582.1 - 0.0048 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 GAM35582.1 - 0.0058 16.4 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM35582.1 - 0.0059 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAM35582.1 - 0.0089 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 GAM35582.1 - 0.029 14.1 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Ubiquitin_4 PF18036.1 GAM35582.1 - 0.047 13.7 0.9 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain Torsin PF06309.11 GAM35582.1 - 0.066 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Torsin CPT PF07931.12 GAM35582.1 - 0.074 12.9 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 GAM35582.1 - 0.075 13.3 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 GAM35582.1 - 0.12 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 GAM35582.1 - 0.17 11.6 0.0 0.51 10.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 GAM35582.1 - 0.23 11.2 1.4 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 GAM35582.1 - 0.26 10.6 0.2 1 8.7 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Isochorismatase PF00857.20 GAM35583.1 - 4.8e-15 56.2 0.1 6.3e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family Zn_clus PF00172.18 GAM35584.1 - 8.8e-09 35.3 12.1 8.8e-09 35.3 12.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM35584.1 - 0.0017 17.4 0.1 0.012 14.7 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ras PF00071.22 GAM35585.1 - 1.8e-51 174.0 0.8 2.7e-50 170.1 0.8 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 GAM35585.1 - 1.4e-18 67.2 0.1 2.1e-17 63.4 0.1 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM35585.1 - 0.00055 19.4 0.1 0.0033 16.9 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_25 PF13481.6 GAM35585.1 - 0.043 13.4 0.1 0.36 10.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 GAM35585.1 - 0.044 13.2 0.0 0.71 9.3 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 GAM35585.1 - 0.076 12.5 0.2 1.9 8.0 0.0 2.5 2 1 1 3 3 3 0 Ferrous iron transport protein B Septin PF00735.18 GAM35585.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Septin RsgA_GTPase PF03193.16 GAM35585.1 - 0.18 11.7 0.0 9.3 6.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Pkinase PF00069.25 GAM35587.1 - 5.8e-18 65.2 0.0 1.8e-14 53.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM35587.1 - 4e-12 46.0 0.0 1.2e-08 34.6 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase TPR_12 PF13424.6 GAM35588.1 - 1e-26 93.0 12.3 1.1e-07 32.0 0.5 7.0 5 2 1 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAM35588.1 - 1.1e-20 72.8 13.8 6.3e-09 35.4 0.0 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat Pkinase PF00069.25 GAM35588.1 - 3.8e-11 42.9 0.0 1e-09 38.1 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain TPR_2 PF07719.17 GAM35588.1 - 7.1e-10 38.2 7.7 0.16 12.1 0.0 8.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM35588.1 - 1.8e-09 38.0 3.6 0.01 16.3 0.0 6.7 6 1 2 8 8 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM35588.1 - 2.5e-09 36.5 5.9 0.13 12.1 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM35588.1 - 1.3e-08 34.3 0.8 0.096 13.0 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM35588.1 - 1.5e-08 34.1 0.6 0.43 10.7 0.1 6.3 6 0 0 6 6 5 2 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 GAM35588.1 - 9.8e-07 28.3 0.0 0.00019 20.8 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase TPR_14 PF13428.6 GAM35588.1 - 1.5e-06 28.5 0.6 29 5.9 0.0 7.2 7 0 0 7 7 6 0 Tetratricopeptide repeat RPN7 PF10602.9 GAM35588.1 - 0.00049 19.8 0.4 4.7 6.9 0.1 3.6 2 1 1 3 3 3 2 26S proteasome subunit RPN7 TPR_6 PF13174.6 GAM35588.1 - 0.0015 19.0 4.0 13 6.6 0.1 6.8 9 0 0 9 9 6 0 Tetratricopeptide repeat EcKinase PF02958.20 GAM35588.1 - 0.0019 17.6 1.1 0.0084 15.5 0.4 2.1 2 0 0 2 2 2 1 Ecdysteroid kinase PPR PF01535.20 GAM35588.1 - 0.0065 16.6 0.3 25 5.4 0.1 4.6 6 0 0 6 6 3 0 PPR repeat ANAPC3 PF12895.7 GAM35588.1 - 0.013 15.8 4.3 4 7.7 0.0 5.8 6 1 1 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GAM35588.1 - 0.016 15.5 2.7 34 5.1 0.1 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat APH PF01636.23 GAM35588.1 - 0.072 13.0 0.4 0.2 11.5 0.4 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_11 PF13414.6 GAM35588.1 - 0.12 12.1 4.3 6.3 6.6 0.1 4.7 5 0 0 5 5 5 0 TPR repeat TPR_16 PF13432.6 GAM35588.1 - 0.14 12.8 2.1 28 5.4 0.0 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat CinA PF02464.17 GAM35589.1 - 2.5e-33 114.8 3.0 6.1e-33 113.6 3.0 1.5 1 1 0 1 1 1 1 Competence-damaged protein SHMT PF00464.19 GAM35590.1 - 2e-197 655.6 0.0 2.4e-197 655.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Tyrosinase PF00264.20 GAM35591.1 - 1.9e-52 178.8 0.2 3.5e-52 177.9 0.0 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase MOSC PF03473.17 GAM35591.1 - 2.3e-29 102.0 0.1 3.9e-29 101.3 0.1 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 GAM35591.1 - 7.6e-10 38.7 0.0 2.3e-09 37.2 0.0 1.9 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain AA_permease_2 PF13520.6 GAM35593.1 - 1.1e-47 162.9 35.8 1.4e-47 162.5 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM35593.1 - 4.4e-17 61.8 35.3 5.9e-17 61.4 35.3 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 GAM35594.1 - 9.5e-15 54.3 0.2 7.6e-14 51.3 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Amino_oxidase PF01593.24 GAM35595.1 - 1.1e-50 173.3 0.2 2.7e-49 168.7 0.2 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM35595.1 - 1.3e-11 44.6 0.2 4.6e-11 42.8 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM35595.1 - 3.2e-08 33.5 0.1 1.4e-07 31.4 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM35595.1 - 7.5e-08 31.9 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM35595.1 - 1.2e-06 27.9 0.3 2e-06 27.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAM35595.1 - 1.2e-06 27.9 0.1 2e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 GAM35595.1 - 6.1e-06 25.5 0.1 1.1e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 GAM35595.1 - 1.1e-05 25.0 0.1 1.6e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM35595.1 - 2.2e-05 23.3 0.0 3.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 GAM35595.1 - 0.00037 20.5 0.3 0.0032 17.5 0.2 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GAM35595.1 - 0.00086 18.6 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GAM35595.1 - 0.0023 18.5 0.1 0.0047 17.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM35595.1 - 0.006 15.7 0.3 0.0088 15.2 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GDI PF00996.18 GAM35595.1 - 0.065 11.7 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Glu_dehyd_C PF16912.5 GAM35595.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus UbiA PF01040.18 GAM35596.1 - 3e-29 102.1 7.3 4e-29 101.7 7.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family NAD_binding_4 PF07993.12 GAM35598.1 - 3.9e-35 121.2 0.0 8.5e-35 120.2 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 GAM35598.1 - 4.6e-25 88.1 0.0 7.9e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAM35598.1 - 2.4e-17 63.2 0.0 6.6e-17 61.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM35598.1 - 4.4e-07 29.6 0.2 1e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 GAM35598.1 - 4.7e-05 23.7 0.0 0.00013 22.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 GAM35598.1 - 0.00013 21.1 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 GAM35598.1 - 0.00019 21.4 0.1 0.00094 19.1 0.0 2.2 3 1 0 3 3 3 1 KR domain Vip3A_N PF12495.8 GAM35598.1 - 0.025 14.5 0.1 0.24 11.3 0.0 2.6 3 0 0 3 3 3 0 Vegetative insecticide protein 3A N terminal RmlD_sub_bind PF04321.17 GAM35598.1 - 0.048 12.7 0.0 3.9 6.5 0.0 2.7 3 0 0 3 3 3 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAM35598.1 - 0.17 11.0 0.0 0.41 9.7 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 GAM35599.1 - 8.5e-28 97.3 46.8 8.5e-28 97.3 46.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM35599.1 - 3.3e-14 52.2 12.7 5.4e-14 51.5 12.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2157 PF09925.9 GAM35599.1 - 5.1 6.9 11.6 0.4 10.5 3.8 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Zn_clus PF00172.18 GAM35600.1 - 1.4e-05 25.1 7.9 3.5e-05 23.8 7.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM35600.1 - 7.9e-05 21.8 1.4 0.00093 18.3 0.2 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Patatin PF01734.22 GAM35601.1 - 9.8e-15 55.3 0.0 2.2e-14 54.1 0.0 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase LPD22 PF18834.1 GAM35601.1 - 0.17 12.1 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 Mg_trans_NIPA PF05653.14 GAM35602.1 - 2.3e-90 302.7 28.4 2.9e-90 302.3 28.4 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 GAM35602.1 - 0.00027 21.1 5.9 0.00027 21.1 5.9 3.2 3 0 0 3 3 3 1 EamA-like transporter family DUF5362 PF17319.2 GAM35602.1 - 0.084 12.7 0.0 0.084 12.7 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5362) DUF4119 PF13494.6 GAM35602.1 - 0.23 11.6 0.2 0.47 10.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) BRCT_2 PF16589.5 GAM35603.1 - 5.7e-10 39.5 0.0 2e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 GAM35603.1 - 0.0021 17.9 0.2 0.0093 15.9 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 GAM35603.1 - 0.049 13.9 0.0 0.43 10.9 0.0 2.4 2 1 0 2 2 2 0 DNA ligase 3 BRCT domain KilA-N PF04383.13 GAM35604.1 - 0.0001 22.1 0.0 0.0037 17.1 0.0 2.6 1 1 0 1 1 1 1 KilA-N domain DUF4587 PF15248.6 GAM35604.1 - 0.88 10.4 5.4 0.49 11.2 1.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) HA2 PF04408.23 GAM35605.1 - 6.7e-16 58.5 0.0 3.4e-15 56.3 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAM35605.1 - 4.4e-13 49.5 0.6 1.4e-12 47.9 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 GAM35605.1 - 1.9e-07 31.3 0.0 4.5e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 GAM35605.1 - 0.00046 20.0 0.0 0.0013 18.5 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Gcn1_N PF12074.8 GAM35606.1 - 3.6e-111 371.9 4.6 2.8e-110 369.0 4.6 2.7 1 0 0 1 1 1 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Ribosomal_L19e PF01280.20 GAM35606.1 - 3.2e-60 202.4 8.0 9.3e-60 200.9 8.0 1.9 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT_EZ PF13513.6 GAM35606.1 - 6.8e-28 96.7 46.9 1.8e-06 28.3 0.0 20.4 17 4 5 22 22 21 7 HEAT-like repeat HEAT PF02985.22 GAM35606.1 - 5.7e-27 91.5 42.1 0.08 13.2 0.3 23.2 29 0 0 29 29 24 7 HEAT repeat HEAT_2 PF13646.6 GAM35606.1 - 4.2e-23 81.5 51.7 9.8e-05 22.7 0.0 15.8 9 4 9 19 19 18 10 HEAT repeats Vac14_Fab1_bd PF12755.7 GAM35606.1 - 2.2e-10 41.0 0.1 2.8 8.6 0.0 7.9 6 3 1 7 7 7 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 GAM35606.1 - 4.7e-10 39.4 0.1 0.37 10.3 0.0 7.2 6 1 1 7 7 7 4 CLASP N terminal Cnd1 PF12717.7 GAM35606.1 - 1.2e-09 38.4 12.7 0.18 11.8 0.0 9.7 8 2 3 11 11 11 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 GAM35606.1 - 2.9e-08 34.1 4.1 0.12 12.5 0.0 6.6 5 1 1 6 6 6 2 Parkin co-regulated protein TIP120 PF08623.10 GAM35606.1 - 0.00016 21.5 7.9 0.013 15.3 0.0 6.4 6 1 1 7 7 7 1 TATA-binding protein interacting (TIP20) DUF3385 PF11865.8 GAM35606.1 - 0.0057 16.6 3.9 3.8 7.4 0.0 5.8 6 2 1 7 7 7 1 Domain of unknown function (DUF3385) RTP1_C1 PF10363.9 GAM35606.1 - 0.03 14.5 7.4 15 5.8 0.0 6.6 6 0 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF937 PF06078.11 GAM35606.1 - 0.88 10.2 12.7 8.8 6.9 0.0 6.0 5 2 0 5 5 5 0 Bacterial protein of unknown function (DUF937) WASH-7_C PF14746.6 GAM35606.1 - 1.7 8.3 6.2 1.4 8.6 2.6 2.4 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal SKG6 PF08693.10 GAM35607.1 - 0.0037 16.6 1.2 0.0086 15.5 1.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 GAM35607.1 - 0.0093 15.4 0.1 0.017 14.6 0.1 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity MFS_2 PF13347.6 GAM35607.1 - 0.0095 14.5 1.2 0.013 14.1 1.2 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Syndecan PF01034.20 GAM35607.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 GAM35607.1 - 0.092 13.6 0.1 0.31 12.0 0.0 2.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 GAM35607.1 - 0.4 10.8 9.2 0.95 9.6 9.2 1.6 1 0 0 1 1 1 0 Podoplanin SDA1 PF05285.12 GAM35608.1 - 0.0075 15.7 0.1 0.0075 15.7 0.1 1.7 2 0 0 2 2 2 1 SDA1 Zn_clus PF00172.18 GAM35609.1 - 1.9e-10 40.7 13.6 1.9e-10 40.7 13.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 GAM35610.1 - 1e-31 109.9 0.1 1.8e-31 109.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35610.1 - 6.4e-21 75.0 0.0 9e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM35610.1 - 2.6e-07 30.7 0.1 2.6e-06 27.5 0.1 2.0 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 GAM35610.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Vac7 PF12751.7 GAM35611.1 - 1.5e-129 432.8 0.7 1.5e-129 432.8 0.7 3.4 2 2 1 3 3 3 2 Vacuolar segregation subunit 7 CorA PF01544.18 GAM35612.1 - 1.3e-26 93.6 0.5 1.4e-18 67.3 0.1 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein REV PF00424.18 GAM35612.1 - 3.9 7.6 10.2 14 5.8 0.4 2.8 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Helo_like_N PF17111.5 GAM35613.1 - 0.094 12.1 7.1 0.0071 15.7 0.9 2.3 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF3824 PF12868.7 GAM35614.1 - 3.3e-33 115.5 37.3 3.3e-33 115.5 37.3 8.6 4 2 4 8 8 8 3 Domain of unknwon function (DUF3824) DUF5134 PF17197.4 GAM35614.1 - 0.67 9.8 3.0 4.5 7.2 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) Ribosomal_L44 PF00935.19 GAM35615.1 - 1.7e-35 121.4 12.2 1.7e-35 121.4 12.2 2.2 2 0 0 2 2 2 1 Ribosomal protein L44 Solute_trans_a PF03619.16 GAM35616.1 - 2.6e-52 178.0 17.9 3.1e-52 177.7 17.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SurA_N_2 PF13623.6 GAM35617.1 - 9.2e-05 22.3 1.2 9.2e-05 22.3 1.2 1.5 2 0 0 2 2 1 1 SurA N-terminal domain TPR_MLP1_2 PF07926.12 GAM35617.1 - 0.00067 19.7 3.4 0.00067 19.7 3.4 2.3 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF4201 PF13870.6 GAM35617.1 - 0.0028 17.4 3.2 0.0028 17.4 3.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) APG6_N PF17675.1 GAM35617.1 - 0.0029 18.1 17.8 0.27 11.7 17.7 2.3 1 1 0 1 1 1 1 Apg6 coiled-coil region DUF3450 PF11932.8 GAM35617.1 - 0.0058 16.0 3.3 0.0058 16.0 3.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) ADIP PF11559.8 GAM35617.1 - 0.0072 16.4 2.8 0.0072 16.4 2.8 2.3 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 GAM35617.1 - 0.0091 16.5 3.5 0.0091 16.5 3.5 2.6 1 1 1 2 2 2 1 Protein of unknown function DUF16 Cep57_CLD_2 PF14197.6 GAM35617.1 - 0.014 15.5 3.7 0.014 15.5 3.7 2.8 2 2 0 2 2 2 0 Centrosome localisation domain of PPC89 ATG16 PF08614.11 GAM35617.1 - 0.019 15.2 5.3 0.019 15.2 5.3 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) GIT_CC PF16559.5 GAM35617.1 - 0.022 14.6 1.3 0.12 12.2 0.3 2.5 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor MCC-bdg_PDZ PF10506.9 GAM35617.1 - 0.024 14.6 0.5 0.067 13.2 0.5 1.7 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TSC22 PF01166.18 GAM35617.1 - 0.03 14.6 0.5 0.12 12.8 0.1 2.2 1 1 0 1 1 1 0 TSC-22/dip/bun family SurA_N_3 PF13624.6 GAM35617.1 - 0.092 12.5 2.5 0.087 12.6 1.1 1.6 2 0 0 2 2 2 0 SurA N-terminal domain Prominin PF05478.11 GAM35617.1 - 0.27 9.1 2.0 0.37 8.7 2.0 1.1 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 GAM35617.1 - 0.49 10.4 7.0 0.084 12.9 1.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 GAM35617.1 - 1.2 9.3 7.5 0.41 10.8 2.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RasGAP_C PF03836.15 GAM35617.1 - 1.3 9.2 8.1 0.13 12.4 2.0 2.2 2 1 0 2 2 2 0 RasGAP C-terminus ZapB PF06005.12 GAM35617.1 - 1.4 9.4 11.8 4.9 7.7 4.4 3.3 2 1 1 3 3 3 0 Cell division protein ZapB DUF724 PF05266.14 GAM35617.1 - 1.6 8.5 15.7 0.033 14.0 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Ax_dynein_light PF10211.9 GAM35617.1 - 1.7 8.5 13.4 0.056 13.4 2.6 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain FlaC_arch PF05377.11 GAM35617.1 - 3.1 8.3 7.8 4.7 7.7 0.1 3.8 2 1 1 4 4 3 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 GAM35617.1 - 3.2 7.0 7.7 5.2 6.3 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lectin_N PF03954.14 GAM35617.1 - 3.5 7.4 5.0 0.91 9.3 0.9 2.1 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF2681 PF10883.8 GAM35617.1 - 3.6 8.0 10.3 0.67 10.4 0.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) DivIC PF04977.15 GAM35617.1 - 4.5 7.1 16.1 0.47 10.3 1.9 3.9 3 1 1 4 4 4 0 Septum formation initiator TMPIT PF07851.13 GAM35617.1 - 4.6 6.4 7.4 0.51 9.5 1.2 1.9 2 0 0 2 2 2 0 TMPIT-like protein Snapin_Pallidin PF14712.6 GAM35617.1 - 4.7 7.7 7.5 7.7 7.0 2.9 3.0 2 1 1 3 3 3 0 Snapin/Pallidin VIT PF08487.10 GAM35617.1 - 5.2 7.3 6.4 8.1 6.7 0.5 2.5 2 1 0 2 2 2 0 Vault protein inter-alpha-trypsin domain DUF4140 PF13600.6 GAM35617.1 - 6.4 7.3 11.3 33 5.0 4.4 3.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fungal_TACC PF12709.7 GAM35617.1 - 7 7.2 11.4 0.67 10.4 0.9 3.3 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins LigT_PEase PF02834.16 GAM35618.1 - 0.00022 21.3 0.0 0.075 13.2 0.0 2.5 2 1 0 2 2 2 2 LigT like Phosphoesterase ubiquitin PF00240.23 GAM35619.1 - 2.3e-25 88.2 0.0 2.5e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAM35619.1 - 3e-14 52.6 0.1 3.3e-14 52.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAM35619.1 - 0.0014 19.1 0.0 0.0045 17.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAM35619.1 - 0.019 14.9 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Elongin_A PF06881.11 GAM35620.1 - 3.3e-28 98.3 0.1 5.1e-28 97.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A p450 PF00067.22 GAM35621.1 - 1.3e-84 284.6 0.0 1.6e-84 284.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DBD_Tnp_Mut PF03108.15 GAM35622.1 - 6.2e-10 38.9 0.3 1.1e-09 38.2 0.3 1.4 1 0 0 1 1 1 1 MuDR family transposase THOC7 PF05615.13 GAM35623.1 - 1.5e-45 154.7 6.9 1.5e-45 154.7 6.9 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 Mod_r PF07200.13 GAM35623.1 - 0.075 13.1 13.7 0.18 11.9 13.7 1.7 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Ead_Ea22 PF13935.6 GAM35623.1 - 1.1 9.9 12.3 9 7.0 12.4 2.5 1 1 0 1 1 1 0 Ead/Ea22-like protein TBCA PF02970.16 GAM35624.1 - 4.7e-24 84.5 3.8 4.7e-24 84.5 3.8 1.7 2 0 0 2 2 2 1 Tubulin binding cofactor A APC_N_CC PF16689.5 GAM35624.1 - 0.064 13.3 0.6 0.28 11.3 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain T3SSipB PF16535.5 GAM35624.1 - 0.075 13.5 6.5 0.22 12.0 6.5 1.8 1 1 0 1 1 1 0 Type III cell invasion protein SipB Band_7 PF01145.25 GAM35625.1 - 2.7e-14 53.6 0.2 2.7e-14 53.6 0.2 2.4 2 1 0 2 2 2 1 SPFH domain / Band 7 family DUF743 PF05332.11 GAM35625.1 - 0.2 11.7 2.4 0.45 10.6 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF743) Glyco_hydro_76 PF03663.14 GAM35626.1 - 4.1e-53 181.2 7.8 5e-53 180.9 7.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 GAM35626.1 - 1.9e-05 24.0 1.6 0.00043 19.5 0.0 2.4 1 1 0 2 2 2 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 GAM35626.1 - 0.0012 17.5 0.2 0.39 9.1 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 C5-epim_C PF06662.13 GAM35626.1 - 0.019 14.5 0.1 4.6 6.7 0.1 2.7 2 1 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_47 PF01532.20 GAM35626.1 - 0.057 12.3 0.1 0.42 9.5 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 47 Glyco_transf_54 PF04666.13 GAM35627.1 - 0.00019 20.4 0.1 0.0075 15.2 0.1 2.7 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_transf_25 PF01755.17 GAM35627.1 - 0.21 11.4 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) MFS_1 PF07690.16 GAM35628.1 - 2.8e-18 66.0 31.9 4.9e-18 65.2 31.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM35628.1 - 4.6e-06 25.8 6.7 4.6e-06 25.8 6.7 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter Methyltransf_31 PF13847.6 GAM35628.1 - 0.081 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NACHT PF05729.12 GAM35629.1 - 1e-06 28.7 0.9 5.5e-06 26.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain SesA PF17107.5 GAM35629.1 - 0.00013 22.2 1.4 0.00026 21.2 0.2 2.2 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 GAM35629.1 - 0.00061 20.2 0.7 0.0082 16.5 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain adh_short_C2 PF13561.6 GAM35630.1 - 7e-21 74.9 0.0 1e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM35630.1 - 1.5e-17 63.7 0.0 2.1e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM35630.1 - 0.00028 20.9 0.0 0.00046 20.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.13 GAM35630.1 - 0.04 13.9 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family NmrA PF05368.13 GAM35630.1 - 0.18 11.3 0.1 0.37 10.3 0.1 1.5 1 1 0 1 1 1 0 NmrA-like family TPR_8 PF13181.6 GAM35631.1 - 0.021 15.0 1.2 0.24 11.7 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM35631.1 - 0.23 11.6 1.5 10 6.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Dynamin_M PF01031.20 GAM35632.1 - 1.3e-18 67.2 0.1 1.5e-13 50.6 0.0 3.2 3 1 0 3 3 3 2 Dynamin central region Dynamin_N PF00350.23 GAM35632.1 - 1.8e-11 44.4 2.6 2.1e-11 44.2 0.8 2.0 2 0 0 2 2 2 1 Dynamin family TauD PF02668.16 GAM35632.1 - 1.3e-06 28.4 1.1 0.00015 21.7 0.0 3.2 4 0 0 4 4 4 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3439 PF11921.8 GAM35632.1 - 0.048 13.6 4.4 0.1 12.6 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF5401 PF17380.2 GAM35632.1 - 5.7 4.9 8.2 0.64 8.0 1.8 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5401) Pkinase_Tyr PF07714.17 GAM35633.1 - 3.1e-08 33.2 0.0 0.00016 21.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GAM35633.1 - 8.8e-08 31.8 0.0 2.8e-07 30.2 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain EspG PF06872.11 GAM35633.1 - 0.1 11.1 0.0 0.24 9.9 0.0 1.5 1 1 1 2 2 2 0 EspG protein Sugar_tr PF00083.24 GAM35634.1 - 2.1e-66 224.6 17.6 2.4e-66 224.5 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM35634.1 - 7.8e-16 57.9 24.5 3.9e-11 42.5 8.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAM35634.1 - 0.16 10.3 14.1 0.27 9.5 10.7 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pyr_redox_2 PF07992.14 GAM35635.1 - 1.1e-10 41.2 0.1 6.2e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAM35635.1 - 4e-07 29.6 0.0 0.0024 17.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAM35635.1 - 5.9e-06 26.4 0.1 2.3e-05 24.5 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM35635.1 - 6.4e-06 25.5 0.0 1.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 GAM35635.1 - 1.2e-05 24.2 0.1 0.0019 17.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 GAM35635.1 - 0.00017 20.8 0.1 0.00046 19.4 0.1 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 GAM35635.1 - 0.00029 21.3 0.1 0.021 15.3 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAM35635.1 - 0.0004 19.9 0.0 0.00059 19.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAM35635.1 - 0.0012 18.2 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 GAM35635.1 - 0.0019 17.5 0.0 0.09 12.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAM35635.1 - 0.003 16.9 0.0 0.49 9.6 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 GAM35635.1 - 0.0034 17.0 1.0 0.023 14.3 0.3 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 GAM35635.1 - 0.004 16.1 0.0 1.9 7.3 0.0 2.4 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.6 GAM35635.1 - 0.01 15.8 0.2 5.2 7.0 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAM35635.1 - 0.061 12.4 0.0 3.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein BNR_2 PF13088.6 GAM35635.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 BNR repeat-like domain Thi4 PF01946.17 GAM35635.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family adh_short PF00106.25 GAM35636.1 - 4.3e-22 78.5 0.9 7.6e-16 58.2 0.2 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35636.1 - 6e-13 48.9 0.2 5.1e-09 36.0 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM35636.1 - 4.3e-06 26.8 0.2 7.6e-06 25.9 0.2 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM35636.1 - 0.00023 20.4 0.0 0.00035 19.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 GAM35636.1 - 0.017 15.3 0.1 0.033 14.4 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_deac_2 PF04748.13 GAM35636.1 - 0.02 14.1 0.1 0.035 13.3 0.1 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase NAD_binding_3 PF03447.16 GAM35636.1 - 0.031 14.9 2.4 0.033 14.8 1.1 1.8 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain ATP-grasp_5 PF13549.6 GAM35636.1 - 0.038 13.4 0.1 0.057 12.9 0.1 1.2 1 0 0 1 1 1 0 ATP-grasp domain Shikimate_DH PF01488.20 GAM35636.1 - 0.051 13.6 0.1 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.16 GAM35637.1 - 1.8e-53 181.7 39.6 2.1e-50 171.6 43.5 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM35637.1 - 1.9e-17 62.9 17.4 2.7e-17 62.4 16.7 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM35637.1 - 9.7e-13 47.8 25.4 1e-12 47.7 6.5 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter UPF0239 PF06783.11 GAM35637.1 - 0.74 10.0 2.8 1.6 8.9 0.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0239) DUF1516 PF07457.11 GAM35637.1 - 5 7.4 8.2 1.2 9.4 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) Fungal_trans PF04082.18 GAM35638.1 - 1.2e-26 93.4 1.0 1.8e-26 92.8 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM35638.1 - 3.7e-08 33.3 11.8 6.7e-08 32.5 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Caps_synth PF05704.12 GAM35639.1 - 3.7e-07 29.8 0.0 6e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 GAM35639.1 - 0.015 15.9 0.0 0.023 15.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif p450 PF00067.22 GAM35640.1 - 2.8e-55 187.9 0.0 4e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HAD_2 PF13419.6 GAM35640.1 - 3.6e-05 23.9 0.0 6.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM35640.1 - 0.08 13.2 0.0 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM35640.1 - 0.092 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Malic_M PF03949.15 GAM35641.1 - 1.1e-91 306.7 0.0 1.4e-91 306.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GAM35641.1 - 1.3e-63 214.2 0.0 2.4e-63 213.2 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF4449 PF14613.6 GAM35642.1 - 0.00026 21.1 0.2 0.00026 21.1 0.2 2.7 4 0 0 4 4 4 1 Protein of unknown function (DUF4449) MRC1 PF09444.10 GAM35642.1 - 7.7 7.0 10.3 0.45 11.0 4.0 2.1 2 0 0 2 2 2 0 MRC1-like domain DnaJ PF00226.31 GAM35643.1 - 8.7e-26 89.8 1.7 1.5e-25 89.1 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 GAM35643.1 - 8.6e-25 87.5 0.0 1.4e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 GAM35643.1 - 1.8e-14 53.8 17.2 3e-14 53.1 17.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 GAM35643.1 - 4.6e-05 23.3 9.1 0.028 14.4 0.7 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Lar_restr_allev PF14354.6 GAM35643.1 - 0.00051 20.4 9.1 0.044 14.2 2.0 2.7 2 1 1 3 3 3 2 Restriction alleviation protein Lar HypA PF01155.19 GAM35643.1 - 0.0039 17.2 6.5 0.58 10.2 0.3 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 GAM35643.1 - 0.5 10.0 7.9 2.7 7.6 1.1 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 GAM35643.1 - 6.7 6.8 10.3 27 4.9 0.9 2.0 1 1 1 2 2 2 0 Double zinc ribbon Macoilin PF09726.9 GAM35644.1 - 7 5.1 20.9 11 4.5 20.9 1.4 1 1 0 1 1 1 0 Macoilin family Ribosomal_S4 PF00163.19 GAM35645.1 - 1.8e-10 41.6 3.9 2.4e-10 41.2 3.9 1.4 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 GAM35645.1 - 4.5e-08 32.7 0.1 7.9e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 S4 domain MFS_1 PF07690.16 GAM35646.1 - 1.4e-19 70.2 22.7 2e-14 53.3 15.5 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily VIT1 PF01988.19 GAM35646.1 - 9.4 6.0 10.8 7.3 6.4 0.3 2.9 3 0 0 3 3 3 0 VIT family OMPdecase PF00215.24 GAM35647.1 - 6e-75 251.7 0.0 6.9e-75 251.5 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MAPEG PF01124.18 GAM35648.1 - 4.5e-23 81.6 2.1 5.6e-23 81.3 2.1 1.1 1 0 0 1 1 1 1 MAPEG family DUF997 PF06196.12 GAM35648.1 - 0.052 13.6 1.0 0.094 12.7 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF997) MBOAT PF03062.19 GAM35649.1 - 2.6e-20 73.1 13.0 4.3e-20 72.4 13.0 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 GAM35649.1 - 0.008 16.4 3.5 0.026 14.8 3.5 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.32 GAM35650.1 - 2.2e-31 107.4 34.2 8.5e-07 29.6 3.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM35650.1 - 1.9e-16 60.1 0.2 0.00078 19.7 0.0 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM35650.1 - 0.013 15.4 0.3 4.5 7.1 0.1 2.7 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 GAM35650.1 - 0.054 11.8 0.0 0.28 9.4 0.0 1.8 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Bacteroid_pep PF14406.6 GAM35650.1 - 0.08 13.3 0.1 0.57 10.6 0.0 2.4 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Bacteroidetes ICMT PF04140.14 GAM35652.1 - 4.7e-06 26.9 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FtsX PF02687.21 GAM35652.1 - 0.098 13.1 0.5 0.098 13.1 0.5 2.0 2 1 0 2 2 2 0 FtsX-like permease family Hexapep PF00132.24 GAM35653.1 - 3.3e-14 51.9 13.4 5.6e-11 41.7 3.1 3.2 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAM35653.1 - 8.3e-11 41.4 13.6 5.9e-10 38.7 2.3 3.0 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 GAM35653.1 - 5e-10 39.5 0.3 8.5e-10 38.7 0.3 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase DUF3517 PF12030.8 GAM35654.1 - 2.6e-105 352.1 0.0 5.4e-105 351.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 GAM35654.1 - 3.5e-38 131.6 0.2 7.5e-38 130.5 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM35654.1 - 7.7e-21 75.0 0.7 4.2e-20 72.6 0.7 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ADD_ATRX PF17981.1 GAM35654.1 - 0.13 12.1 0.1 0.34 10.8 0.1 1.6 1 0 0 1 1 1 0 Cysteine Rich ADD domain TFIIE_alpha PF02002.17 GAM35655.1 - 7.9e-10 38.5 0.1 4.2e-09 36.2 0.1 2.1 1 1 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 GAM35655.1 - 0.024 14.1 0.9 0.12 11.9 1.0 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 GAM35655.1 - 0.041 14.0 0.4 0.15 12.2 0.4 2.0 1 1 1 2 2 2 0 Zinc ribbon domain Cwf_Cwc_15 PF04889.12 GAM35655.1 - 5.3 6.7 17.2 1.7 8.4 10.9 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PseudoU_synth_1 PF01416.20 GAM35656.1 - 4.9e-11 43.1 0.0 5e-09 36.6 0.0 2.7 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF4441 PF14536.6 GAM35656.1 - 0.011 15.9 1.6 0.011 15.9 1.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4441) Alpha-E PF04168.12 GAM35656.1 - 0.2 11.4 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Anillin PF08174.11 GAM35657.1 - 2.1e-08 34.7 0.0 4.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 GAM35657.1 - 4.1e-08 33.7 0.0 1.3e-07 32.1 0.0 1.9 1 0 0 1 1 1 1 PH domain DEAD PF00270.29 GAM35658.1 - 5.2e-33 114.3 0.1 1.1e-32 113.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM35658.1 - 7.1e-17 61.7 0.1 3.7e-15 56.2 0.3 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM35658.1 - 1.3e-06 28.5 0.0 0.051 13.6 0.0 2.6 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit SNF2_N PF00176.23 GAM35658.1 - 0.031 13.0 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain SNF2_N PF00176.23 GAM35660.1 - 1.1e-06 27.6 0.0 1.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 GAM35660.1 - 0.0012 18.8 0.0 0.0025 17.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM35660.1 - 0.0086 15.9 0.0 0.02 14.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 GAM35660.1 - 0.012 14.5 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 DEAD_2 PF06733.15 GAM35660.1 - 0.034 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 DUF2075 PF09848.9 GAM35660.1 - 0.088 12.0 0.0 0.098 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RRM_1 PF00076.22 GAM35661.1 - 2.1e-15 56.3 0.0 5.6e-15 54.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Helicase_C PF00271.31 GAM35661.1 - 0.036 14.4 0.0 0.067 13.5 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain KBP_C PF12309.8 GAM35662.1 - 0.03 13.9 1.9 0.059 12.9 1.9 1.4 1 0 0 1 1 1 0 KIF-1 binding protein C terminal GreA_GreB_N PF03449.15 GAM35662.1 - 0.034 14.3 2.8 0.14 12.3 2.8 2.1 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal DUF948 PF06103.11 GAM35662.1 - 0.076 13.3 0.8 0.55 10.5 0.0 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Rotamase PF00639.21 GAM35663.1 - 1.6e-22 80.3 0.0 2.4e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAM35663.1 - 5.4e-15 55.9 0.0 7.6e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 GAM35663.1 - 3.1e-10 40.0 1.3 3.1e-10 40.0 1.3 1.9 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 GAM35663.1 - 0.00012 22.9 0.0 0.00017 22.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW_1 PF18507.1 GAM35663.1 - 0.018 14.7 0.3 0.018 14.7 0.3 1.7 2 0 0 2 2 2 0 WW domain DUF2188 PF09954.9 GAM35663.1 - 0.093 12.9 0.1 1 9.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) DUF2379 PF09543.10 GAM35663.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) RNA_POL_M_15KD PF02150.16 GAM35664.1 - 2.6e-11 43.2 1.6 2.6e-11 43.2 1.6 3.1 2 1 1 3 3 3 1 RNA polymerases M/15 Kd subunit GFA PF04828.14 GAM35664.1 - 0.00052 20.3 5.2 0.34 11.3 2.1 2.5 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme C1_1 PF00130.22 GAM35664.1 - 0.004 17.0 6.2 0.48 10.4 1.2 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.6 GAM35664.1 - 5 7.0 10.2 30 4.5 4.6 3.3 2 1 0 2 2 2 0 zinc-ribbon domain Ribosomal_L14 PF00238.19 GAM35665.1 - 1.2e-47 161.0 0.9 1.3e-47 160.9 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Phage_antitermQ PF06530.12 GAM35665.1 - 0.17 11.8 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Phage antitermination protein Q SET PF00856.28 GAM35666.1 - 1e-11 45.6 0.0 3.7e-08 33.9 0.0 2.7 2 0 0 2 2 2 2 SET domain SAF PF08666.12 GAM35666.1 - 0.068 13.8 0.0 3.4 8.4 0.0 2.6 2 0 0 2 2 2 0 SAF domain FAM76 PF16046.5 GAM35666.1 - 4.3 6.6 6.8 0.49 9.7 1.9 1.9 2 0 0 2 2 2 0 FAM76 protein SNO PF01174.19 GAM35667.1 - 5.5e-53 179.6 0.0 5e-42 143.9 0.0 2.2 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 GAM35667.1 - 2.2e-09 37.2 0.0 5.4e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 GAM35667.1 - 0.00037 20.3 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 GAM35667.1 - 0.0057 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_hydro_64 PF16483.5 GAM35669.1 - 1.2e-138 462.4 13.0 1.4e-138 462.2 13.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Acyltransferase PF01553.21 GAM35670.1 - 1.6e-32 111.9 0.0 2.5e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Phage_holin_3_6 PF07332.11 GAM35670.1 - 0.077 13.0 2.1 0.15 12.1 2.1 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TPR_1 PF00515.28 GAM35671.1 - 1e-45 151.8 24.3 1.1e-09 37.7 0.6 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 GAM35671.1 - 7.2e-41 135.0 28.7 6.7e-07 29.0 0.2 11.1 11 0 0 11 11 11 7 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM35671.1 - 4e-33 113.5 28.6 8.7e-25 86.8 0.9 5.0 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 GAM35671.1 - 6.6e-30 100.8 15.6 2.8e-05 24.0 0.1 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 GAM35671.1 - 2.2e-26 91.2 17.9 0.00017 21.2 0.0 9.4 8 3 2 10 10 10 6 TPR repeat TPR_19 PF14559.6 GAM35671.1 - 2.1e-24 85.8 24.3 3.5e-08 33.8 0.1 9.0 6 3 1 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 GAM35671.1 - 4.8e-23 81.5 20.1 9.2e-06 26.2 0.0 8.5 6 2 2 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 GAM35671.1 - 5e-22 76.7 16.7 0.0037 18.0 0.0 9.5 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 GAM35671.1 - 6.4e-17 61.6 22.0 0.01 16.1 0.0 8.5 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 GAM35671.1 - 2.8e-16 58.6 19.0 0.057 13.8 0.0 10.1 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAM35671.1 - 2.6e-12 45.8 12.3 0.056 13.5 0.0 7.5 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAM35671.1 - 3.6e-09 36.6 3.5 0.053 13.7 0.0 6.1 3 1 4 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAM35671.1 - 1.1e-07 32.0 24.1 1 10.2 0.0 9.5 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM35671.1 - 3.4e-06 26.8 3.2 0.88 9.5 0.1 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat Sel1 PF08238.12 GAM35671.1 - 9e-05 23.0 2.3 16 6.3 0.0 6.0 6 0 0 6 6 5 0 Sel1 repeat TPR_21 PF09976.9 GAM35671.1 - 0.0012 18.6 8.7 0.2 11.3 0.9 4.4 2 1 2 4 4 4 1 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 GAM35671.1 - 0.0064 15.9 11.6 0.039 13.3 0.0 3.6 4 1 0 4 4 4 2 MalT-like TPR region ChAPs PF09295.10 GAM35671.1 - 0.16 11.0 2.3 2.9 6.8 0.2 3.1 2 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Ribos_L4_asso_C PF14374.6 GAM35671.1 - 0.18 11.9 1.0 3.1 7.9 0.0 3.0 3 0 0 3 3 2 0 60S ribosomal protein L4 C-terminal domain TPR_4 PF07721.14 GAM35671.1 - 1.4 9.7 6.7 1.4e+02 3.5 0.0 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat TMEM208_SND2 PF05620.11 GAM35672.1 - 3.6e-56 189.5 0.0 4.1e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 LTXXQ PF07813.12 GAM35673.1 - 0.13 13.0 6.2 5.1 7.9 0.5 3.8 3 0 0 3 3 3 0 LTXXQ motif family protein RINGv PF12906.7 GAM35674.1 - 2.2e-16 59.7 8.9 3.7e-16 59.0 8.9 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 GAM35674.1 - 0.0012 19.1 7.7 0.0021 18.4 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain S1FA PF04689.13 GAM35674.1 - 0.19 11.9 0.7 1 9.6 0.7 2.2 1 0 0 1 1 1 0 DNA binding protein S1FA zf-RING_4 PF14570.6 GAM35674.1 - 0.44 10.4 6.6 0.73 9.7 6.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 GAM35674.1 - 0.65 10.1 2.2 1.5 9.0 2.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 GAM35674.1 - 4 7.7 5.6 7.9 6.7 5.6 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 GAM35674.1 - 4.7 7.2 4.9 9.5 6.2 4.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HeLo PF14479.6 GAM35675.1 - 8.3e-06 25.8 0.6 0.0042 17.0 0.6 2.5 1 1 0 1 1 1 1 Prion-inhibition and propagation Peptidase_S64 PF08192.11 GAM35675.1 - 0.0034 16.0 0.0 0.038 12.5 0.0 2.1 2 0 0 2 2 2 1 Peptidase family S64 Pkinase_Tyr PF07714.17 GAM35675.1 - 0.16 11.2 0.1 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Ras_bdg_2 PF14847.6 GAM35675.1 - 0.2 12.0 0.9 1 9.7 1.0 2.1 1 1 1 2 2 2 0 Ras-binding domain of Byr2 ACC_central PF08326.12 GAM35676.1 - 3.5e-279 928.1 0.0 4.6e-279 927.7 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 GAM35676.1 - 1.3e-188 627.7 0.0 2.7e-188 626.6 0.0 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 GAM35676.1 - 1.5e-54 184.7 0.0 3.3e-54 183.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAM35676.1 - 3.4e-28 98.4 0.1 6.7e-28 97.4 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAM35676.1 - 1.2e-22 80.1 0.0 7.4e-20 71.1 0.0 3.2 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAM35676.1 - 5.3e-17 61.4 0.4 1.5e-16 60.0 0.1 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 GAM35676.1 - 0.00028 21.0 0.0 0.001 19.1 0.0 2.0 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAM35676.1 - 0.00077 19.1 0.0 0.0021 17.7 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAM35676.1 - 0.0056 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 GAM35676.1 - 0.012 15.4 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like GxGYxYP_N PF16216.5 GAM35676.1 - 0.025 14.8 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal ATPgrasp_Ter PF15632.6 GAM35676.1 - 0.17 11.6 0.0 0.46 10.2 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon His_Phos_1 PF00300.22 GAM35677.1 - 7.3e-10 38.9 0.0 2.1e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Isochorismatase PF00857.20 GAM35680.1 - 3.4e-45 154.4 0.0 8.4e-45 153.1 0.0 1.7 3 0 0 3 3 3 1 Isochorismatase family FAR1 PF03101.15 GAM35680.1 - 0.0049 17.5 0.0 0.0089 16.7 0.0 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 GAM35680.1 - 0.12 12.7 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT Sedlin_N PF04628.13 GAM35681.1 - 1.6e-40 138.3 0.0 1.9e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 GAM35681.1 - 0.0013 18.7 0.0 0.03 14.2 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family Ferrochelatase PF00762.19 GAM35681.1 - 0.04 13.0 0.1 0.092 11.8 0.1 1.6 1 1 1 2 2 2 0 Ferrochelatase DUF2040 PF09745.9 GAM35682.1 - 1.7e-37 128.1 23.5 1.7e-37 128.1 23.5 3.8 3 1 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Zip PF02535.22 GAM35683.1 - 3.7e-25 88.9 4.8 2.8e-16 59.7 0.1 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter NicO PF03824.16 GAM35683.1 - 0.0069 15.8 2.5 0.0069 15.8 2.5 2.1 2 0 0 2 2 2 1 High-affinity nickel-transport protein DUF4834 PF16118.5 GAM35683.1 - 2.2 9.3 3.9 4.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Endonuclease_NS PF01223.23 GAM35684.1 - 5.2e-62 209.6 0.0 6.2e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Pkinase PF00069.25 GAM35685.1 - 3e-17 62.9 0.0 7e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain zf-RING_UBOX PF13445.6 GAM35685.1 - 5.4e-08 32.7 8.1 8.2e-06 25.7 3.2 3.0 2 0 0 2 2 2 2 RING-type zinc-finger zf-NOSIP PF15906.5 GAM35685.1 - 2.1e-05 24.5 0.0 5.9e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 GAM35685.1 - 9.4e-05 22.7 12.0 0.0096 16.2 5.6 3.2 2 1 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 GAM35685.1 - 0.00033 20.5 5.6 0.00033 20.5 5.6 2.8 2 2 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAM35685.1 - 0.00035 20.4 3.4 0.00035 20.4 3.4 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Barttin PF15462.6 GAM35685.1 - 0.00071 19.4 1.4 0.0013 18.6 1.4 1.4 1 0 0 1 1 1 1 Bartter syndrome, infantile, with sensorineural deafness (Barttin) zf-C3HC4 PF00097.25 GAM35685.1 - 0.0036 17.1 2.9 0.0036 17.1 2.9 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM35685.1 - 0.0039 17.0 15.1 0.081 12.8 7.1 3.4 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 GAM35685.1 - 0.005 16.2 1.3 0.005 16.2 1.3 3.5 2 1 1 3 3 2 2 Rtf2 RING-finger FYVE PF01363.21 GAM35685.1 - 0.016 15.3 10.0 0.088 13.0 4.3 3.2 2 1 0 2 2 2 0 FYVE zinc finger zf-C3HC4_5 PF17121.5 GAM35685.1 - 0.044 13.7 1.2 0.15 12.0 1.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Kinase-like PF14531.6 GAM35685.1 - 0.14 11.4 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like MAP7 PF05672.11 GAM35685.1 - 0.72 9.5 28.3 1.5 8.5 28.3 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family zf-RING_4 PF14570.6 GAM35685.1 - 1.1 9.1 6.7 57 3.6 4.7 3.6 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Vfa1 PF08432.10 GAM35685.1 - 1.3 9.3 7.6 0.72 10.2 4.8 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Sec7 PF01369.20 GAM35686.1 - 1.5e-33 116.0 0.1 2.3e-33 115.4 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 GAM35686.1 - 3.9e-06 27.3 0.1 1.5e-05 25.4 0.1 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 GAM35686.1 - 1e-05 25.9 0.1 2.6e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Peptidase_M14 PF00246.24 GAM35687.1 - 2e-74 251.0 0.0 2.7e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 GAM35687.1 - 5e-05 23.6 0.2 0.00012 22.4 0.2 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide bZIP_2 PF07716.15 GAM35687.1 - 0.036 14.1 0.7 0.073 13.2 0.3 1.7 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 GAM35687.1 - 0.13 12.4 0.8 0.3 11.2 0.8 1.5 1 0 0 1 1 1 0 bZIP transcription factor HSP70 PF00012.20 GAM35688.1 - 0.16 10.1 0.0 0.25 9.5 0.0 1.2 1 0 0 1 1 1 0 Hsp70 protein CorA PF01544.18 GAM35690.1 - 1.7e-09 37.4 1.3 2.9e-09 36.7 1.3 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein NicO PF03824.16 GAM35691.1 - 6e-61 206.3 12.8 8.5e-57 192.6 4.6 2.2 2 0 0 2 2 2 2 High-affinity nickel-transport protein DNA_pol_B_thumb PF14791.6 GAM35692.1 - 4.4e-21 74.8 0.1 3.1e-20 72.1 0.5 2.3 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 GAM35692.1 - 9.2e-20 70.2 2.2 1.2e-19 69.9 1.1 1.8 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 GAM35692.1 - 3.9e-16 59.3 0.1 1.2e-15 57.7 0.1 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 GAM35692.1 - 5.3e-09 36.3 0.0 4.8e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 GAM35692.1 - 0.0046 17.3 0.0 0.0098 16.3 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 GAM35692.1 - 0.043 13.9 0.1 0.087 12.9 0.1 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PhoLip_ATPase_C PF16212.5 GAM35693.1 - 8.3e-83 278.0 18.5 8.3e-83 278.0 18.5 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAM35693.1 - 1.6e-26 91.8 8.1 4.7e-26 90.3 8.1 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GAM35693.1 - 2e-11 43.8 0.0 9.9e-11 41.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM35693.1 - 4.4e-11 43.5 1.8 3.9e-06 27.3 0.2 3.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAM35693.1 - 4.3e-06 26.4 0.0 1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAM35693.1 - 0.0029 17.4 0.0 0.02 14.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RNase_PH PF01138.21 GAM35694.1 - 9.6e-17 61.7 0.0 1.7e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAM35694.1 - 8.3e-08 32.2 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.12 GAM35695.1 - 1.9e-75 253.8 15.2 3.2e-75 253.0 15.2 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Med22 PF06179.12 GAM35695.1 - 5.4e-12 45.9 0.0 5.4e-12 45.9 0.0 2.6 2 1 1 3 3 3 1 Surfeit locus protein 5 subunit 22 of Mediator complex Tho2 PF11262.8 GAM35695.1 - 0.37 10.0 2.7 0.61 9.2 2.7 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CDC45 PF02724.14 GAM35695.1 - 0.62 8.3 12.3 0.67 8.2 12.3 1.2 1 0 0 1 1 1 0 CDC45-like protein PA26 PF04636.13 GAM35695.1 - 1.1 8.1 5.0 1.6 7.6 5.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TLP-20 PF06088.11 GAM35695.1 - 3 7.7 7.2 17 5.3 0.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nop53 PF07767.11 GAM35695.1 - 8.1 5.7 25.1 14 4.9 25.1 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DHFR_1 PF00186.19 GAM35696.1 - 1.3e-20 73.7 0.1 4.3e-14 52.5 0.0 3.5 2 1 0 2 2 2 2 Dihydrofolate reductase Voltage_CLC PF00654.20 GAM35697.1 - 3.6e-88 296.2 23.6 3.6e-88 296.2 23.6 1.9 2 1 0 2 2 2 1 Voltage gated chloride channel EthD PF07110.11 GAM35697.1 - 0.16 13.2 0.2 0.32 12.2 0.2 1.6 1 0 0 1 1 1 0 EthD domain Lipase_GDSL_2 PF13472.6 GAM35698.1 - 1.8e-25 90.3 0.0 3.2e-25 89.5 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAM35698.1 - 6.3e-18 65.5 0.0 8e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DASH_Spc34 PF08657.10 GAM35699.1 - 0.0014 18.5 2.5 0.14 11.9 0.1 2.1 2 0 0 2 2 2 2 DASH complex subunit Spc34 CALCOCO1 PF07888.11 GAM35699.1 - 0.019 13.9 0.1 0.029 13.3 0.1 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cortex-I_coil PF09304.10 GAM35699.1 - 0.023 14.9 0.7 0.048 13.9 0.5 1.7 1 1 0 1 1 1 0 Cortexillin I, coiled coil Snapin_Pallidin PF14712.6 GAM35699.1 - 0.025 15.0 0.7 0.025 15.0 0.7 2.3 3 0 0 3 3 3 0 Snapin/Pallidin DUF3456 PF11938.8 GAM35699.1 - 0.031 14.8 0.3 0.064 13.8 0.3 1.6 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP Ribosomal_S15 PF00312.22 GAM35699.1 - 0.1 12.8 1.9 0.84 9.9 0.4 2.9 2 1 1 3 3 3 0 Ribosomal protein S15 FliJ PF02050.16 GAM35699.1 - 0.11 12.7 1.2 0.21 11.8 0.2 1.9 2 0 0 2 2 2 0 Flagellar FliJ protein FlxA PF14282.6 GAM35699.1 - 0.43 10.6 3.2 6.2 6.9 2.4 2.2 1 1 1 2 2 2 0 FlxA-like protein Tropomyosin_1 PF12718.7 GAM35699.1 - 0.55 10.4 5.4 0.29 11.3 0.8 2.5 2 2 1 3 3 3 0 Tropomyosin like XhlA PF10779.9 GAM35699.1 - 4.3 7.6 6.8 0.52 10.6 0.4 2.7 3 1 1 4 4 4 0 Haemolysin XhlA Isochorismatase PF00857.20 GAM35701.1 - 2.1e-30 106.2 0.4 2.5e-30 105.9 0.4 1.1 1 0 0 1 1 1 1 Isochorismatase family HK PF02110.15 GAM35702.1 - 3.1e-71 239.6 0.7 3.1e-71 239.6 0.7 1.7 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 GAM35702.1 - 2.2e-57 193.3 3.2 3.4e-57 192.7 3.2 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 GAM35702.1 - 4.2e-05 23.1 0.3 0.0002 20.8 0.0 2.2 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase eIF-5_eIF-2B PF01873.17 GAM35703.1 - 2.7e-39 133.6 0.0 5e-39 132.8 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 GAM35703.1 - 1.8e-20 72.8 0.0 1.8e-20 72.8 0.0 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DUF1981 PF09324.10 GAM35704.1 - 0.18 11.7 3.3 6.1 6.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) MFS_1 PF07690.16 GAM35705.1 - 5.6e-42 143.9 43.9 5.6e-42 143.9 43.9 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM35705.1 - 1e-14 53.9 25.2 1.4e-14 53.4 25.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM35705.1 - 0.00038 19.4 12.2 0.00038 19.4 12.2 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter Oxidored_q2 PF00420.24 GAM35705.1 - 0.091 12.4 7.6 1.4 8.6 0.0 3.4 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Zn_clus PF00172.18 GAM35706.1 - 2.8e-05 24.1 4.5 2.8e-05 24.1 4.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lbh PF15317.6 GAM35706.1 - 0.48 11.3 2.6 1.2 10.0 0.2 2.6 2 0 0 2 2 2 0 Cardiac transcription factor regulator, Developmental protein mRNA_cap_enzyme PF01331.19 GAM35707.1 - 4.6e-55 186.5 0.5 4.6e-55 186.5 0.5 1.4 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 GAM35707.1 - 7.8e-37 126.2 0.3 1.7e-36 125.1 0.2 1.6 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 GAM35707.1 - 8.5e-10 38.6 0.1 5.1e-07 29.5 0.3 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 GAM35707.1 - 0.0085 16.4 0.4 0.016 15.5 0.1 1.7 2 0 0 2 2 2 1 RNA ligase ketoacyl-synt PF00109.26 GAM35708.1 - 3.6e-60 203.7 4.3 4e-59 200.2 0.6 2.3 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAM35708.1 - 1.9e-32 111.7 1.3 4.8e-32 110.4 1.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SCA7 PF08313.12 GAM35708.1 - 4.3e-31 106.6 0.5 2.8e-30 104.0 0.6 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain Thiolase_N PF00108.23 GAM35708.1 - 1.5e-05 24.5 0.4 0.00033 20.1 0.1 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAM35708.1 - 0.091 12.4 2.4 0.79 9.4 0.4 2.7 2 0 0 2 2 2 0 Thiolase, C-terminal domain Cut8 PF08559.10 GAM35708.1 - 0.12 12.0 0.6 0.27 10.8 0.6 1.6 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein CDC45 PF02724.14 GAM35708.1 - 0.25 9.6 11.1 0.37 9.0 11.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2151 PF10221.9 GAM35708.1 - 0.56 8.7 6.9 0.78 8.3 6.9 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Arginase PF00491.21 GAM35709.1 - 4.4e-91 305.3 0.0 5.3e-91 305.0 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 GAM35709.1 - 0.008 16.4 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 UPF0489 domain Ras PF00071.22 GAM35710.1 - 8.8e-53 178.2 0.0 1e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM35710.1 - 6.8e-19 68.3 0.0 9.4e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM35710.1 - 3.1e-06 26.8 0.0 4.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MFS_1 PF07690.16 GAM35711.1 - 7.8e-21 74.4 32.3 7.3e-20 71.2 32.1 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM35711.1 - 4.3e-07 28.8 17.8 7.8e-07 27.9 17.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1349 PF07081.11 GAM35712.1 - 1.1e-30 106.6 0.0 1.3e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) GRDP-like PF07173.12 GAM35713.1 - 3.8e-18 66.5 0.0 2.9e-15 57.1 0.0 2.7 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Iwr1 PF08574.10 GAM35716.1 - 9.7e-23 81.0 9.6 9.7e-23 81.0 9.6 3.0 3 0 0 3 3 3 1 Transcription factor Iwr1 NAM-associated PF14303.6 GAM35716.1 - 0.0032 18.2 2.8 0.0032 18.2 2.8 2.3 3 1 0 3 3 3 1 No apical meristem-associated C-terminal domain GET2 PF08690.10 GAM35716.1 - 0.34 10.6 2.7 0.58 9.8 2.7 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 RRM_1 PF00076.22 GAM35717.1 - 3.9e-38 129.1 0.0 1.8e-11 43.7 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM35717.1 - 4.8e-15 55.2 0.0 0.0013 18.6 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM PF10378.9 GAM35717.1 - 3.7e-07 29.8 1.3 2.5e-06 27.1 1.3 2.5 1 0 0 1 1 1 1 Putative RRM domain RRM_7 PF16367.5 GAM35717.1 - 2.2e-06 27.7 0.0 0.0033 17.5 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif DUF4523 PF15023.6 GAM35717.1 - 3.7e-05 23.6 0.0 0.12 12.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_3 PF08777.11 GAM35717.1 - 0.0002 21.3 0.1 0.38 10.8 0.1 3.0 3 0 0 3 3 3 2 RNA binding motif Spo7_2_N PF15407.6 GAM35717.1 - 0.013 15.1 0.0 0.49 10.1 0.0 2.7 2 0 0 2 2 2 0 Sporulation protein family 7 RRM_Rrp7 PF17799.1 GAM35717.1 - 0.027 14.3 0.0 1.8 8.3 0.0 3.2 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain RNA_bind PF08675.11 GAM35717.1 - 0.15 12.1 0.2 0.76 9.8 0.0 2.3 3 0 0 3 3 3 0 RNA binding domain tRNA-synt_2 PF00152.20 GAM35718.1 - 1.6e-88 296.8 0.0 2.4e-88 296.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAM35718.1 - 1.8e-08 34.3 0.0 3.2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 GAM35718.1 - 0.068 13.4 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain MC1 PF05854.11 GAM35718.1 - 0.086 13.1 0.6 0.22 11.8 0.6 1.6 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 Ecl1 PF12855.7 GAM35719.1 - 1.7e-38 133.5 57.8 2.9e-37 129.5 39.2 3.1 2 1 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 GAM35719.1 - 0.013 15.6 3.5 0.027 14.6 3.5 1.4 1 0 0 1 1 1 0 MYND finger zf-FLZ PF04570.14 GAM35719.1 - 0.31 10.6 5.7 1.3 8.5 5.7 1.9 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 GAM35719.1 - 0.82 9.8 6.3 7 6.9 6.3 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) YL1 PF05764.13 GAM35720.1 - 7e-64 216.3 30.1 7e-64 216.3 30.1 3.0 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 GAM35720.1 - 5.3e-10 38.9 0.0 9.2e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain PUF PF00806.19 GAM35721.1 - 1.9e-29 99.6 0.0 3.3e-05 23.3 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 GAM35721.1 - 2.2e-10 40.2 0.0 5.1e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ham1p_like PF01725.16 GAM35722.1 - 2.4e-43 148.3 0.0 2.7e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family SNF2_N PF00176.23 GAM35723.1 - 4.5e-16 58.5 0.0 3.5e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.15 GAM35723.1 - 5.4e-06 26.5 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAM35723.1 - 6.7e-06 26.4 0.0 1.7e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DcpS PF05652.12 GAM35724.1 - 9.7e-37 126.0 0.0 1.6e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 GAM35724.1 - 1.9e-30 105.7 0.0 3.8e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding UDG PF03167.19 GAM35724.1 - 0.094 12.7 0.1 0.19 11.7 0.0 1.5 2 0 0 2 2 2 0 Uracil DNA glycosylase superfamily Peptidase_C12 PF01088.21 GAM35725.1 - 1.2e-53 182.0 0.0 1.5e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MT-A70 PF05063.14 GAM35726.1 - 1.1e-21 77.5 0.0 1.7e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 MT-A70 RNase_H2_suC PF08615.11 GAM35726.1 - 1.2e-19 70.8 0.0 2.3e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RNase_T PF00929.24 GAM35727.1 - 1.8e-20 74.1 0.0 4.1e-20 73.0 0.0 1.6 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 GAM35727.1 - 0.094 12.4 0.0 0.6 9.8 0.0 2.1 1 1 0 1 1 1 0 3'-5' exonuclease Nop53 PF07767.11 GAM35728.1 - 1.4e-93 314.5 44.4 3.9e-92 309.7 44.4 2.1 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF4407 PF14362.6 GAM35728.1 - 5.3 6.3 9.1 9.5 5.5 9.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Myb_Cef PF11831.8 GAM35729.1 - 1.6e-51 175.2 2.9 1.6e-51 175.2 2.9 4.0 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 GAM35729.1 - 1.9e-21 76.0 5.5 7.5e-11 42.1 0.7 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM35729.1 - 2.2e-20 72.6 3.3 1.9e-13 50.4 0.7 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 GAM35729.1 - 0.027 14.5 1.3 0.22 11.6 0.0 3.0 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF4457 PF14652.6 GAM35729.1 - 0.1 11.9 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) MOZ_SAS PF01853.18 GAM35730.1 - 3.5e-80 267.9 0.0 4.9e-80 267.4 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GAM35730.1 - 3.1e-22 77.9 0.3 6.9e-22 76.8 0.3 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 GAM35730.1 - 5e-20 71.1 0.1 1.1e-19 70.1 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 GAM35730.1 - 0.0024 18.3 0.0 0.0049 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM35730.1 - 0.053 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Agenet PF05641.12 GAM35730.1 - 0.067 13.7 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 Agenet domain DUF2744 PF10910.8 GAM35730.1 - 0.42 10.6 2.0 0.54 10.2 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2744) Ferlin_C PF16165.5 GAM35730.1 - 0.66 9.9 2.8 0.32 10.9 0.3 1.8 2 0 0 2 2 2 0 Ferlin C-terminus F1F0-ATPsyn_F PF10791.9 GAM35732.1 - 1.7e-39 134.2 0.6 9.2e-33 112.6 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 GAM35732.1 - 0.0034 17.7 0.0 0.029 14.7 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.12 GAM35733.1 - 4.9e-36 122.9 1.5 6.8e-36 122.4 1.5 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region HEAT_2 PF13646.6 GAM35734.1 - 2.6e-28 98.2 2.1 9.9e-13 48.3 0.3 3.5 2 2 1 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 GAM35734.1 - 3.3e-21 73.7 0.0 0.0045 17.5 0.0 6.5 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 GAM35734.1 - 9.2e-11 41.0 1.1 0.79 10.1 0.0 6.1 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 GAM35734.1 - 6.4e-05 23.4 3.5 3.4 8.3 0.0 5.2 4 2 2 6 6 6 1 HEAT-like repeat Cnd1 PF12717.7 GAM35734.1 - 0.001 19.1 0.0 0.91 9.5 0.0 3.2 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GAM35734.1 - 0.0024 17.9 0.1 0.098 12.7 0.0 3.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 GAM35734.1 - 0.011 16.1 0.0 0.46 10.8 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion RuvA_C PF07499.13 GAM35734.1 - 0.08 13.4 2.2 11 6.5 0.1 3.1 3 0 0 3 3 3 0 RuvA, C-terminal domain TFIIS_C PF01096.18 GAM35735.1 - 2.8e-13 49.5 3.3 2.8e-13 49.5 3.3 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 GAM35735.1 - 8.9e-06 25.5 6.4 1.2e-05 25.1 0.2 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit CxC7 PF18866.1 GAM35735.1 - 0.023 14.8 1.6 1.7 8.9 0.1 3.1 2 1 1 3 3 3 0 CxC7 like cysteine cluster associated with KDZ transposases PNP_UDP_1 PF01048.20 GAM35735.1 - 0.099 11.9 0.0 0.15 11.2 0.0 1.3 1 1 0 1 1 1 0 Phosphorylase superfamily Ribosomal_S27e PF01667.17 GAM35735.1 - 0.27 11.0 4.1 5.6 6.8 0.0 3.1 2 1 1 3 3 3 0 Ribosomal protein S27 Zn_ribbon_recom PF13408.6 GAM35735.1 - 0.33 11.5 11.1 7.7 7.1 0.9 3.2 2 1 0 3 3 3 0 Recombinase zinc beta ribbon domain YhfH PF14149.6 GAM35735.1 - 0.45 10.5 5.6 16 5.6 0.1 3.2 3 0 0 3 3 3 0 YhfH-like protein GFA PF04828.14 GAM35735.1 - 0.46 10.9 5.2 1.7 9.0 0.2 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.6 GAM35735.1 - 0.47 10.2 12.9 2.1 8.1 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.7 GAM35735.1 - 0.5 10.4 10.7 38 4.4 10.7 2.6 1 1 0 1 1 1 0 Double zinc ribbon zf-trcl PF13451.6 GAM35735.1 - 0.64 9.9 7.9 1.2 9.1 1.0 3.1 3 0 0 3 3 3 0 Probable zinc-ribbon domain DNA_RNApol_7kD PF03604.13 GAM35735.1 - 8.1 6.2 13.7 5.3 6.8 0.2 3.8 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.6 GAM35735.1 - 8.6 5.9 10.5 12 5.4 0.0 3.6 4 0 0 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 GAM35735.1 - 9.3 6.3 8.6 22 5.1 0.7 2.8 2 2 1 3 3 3 0 Putative transposase DNA-binding domain Nipped-B_C PF12830.7 GAM35736.1 - 2e-46 158.3 3.6 8.6e-45 153.0 0.6 3.2 2 1 1 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 GAM35736.1 - 4.6e-12 46.0 5.5 7.2e-11 42.2 3.2 3.3 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 GAM35736.1 - 3.5e-05 23.1 1.0 0.0047 16.2 0.0 2.9 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 GAM35736.1 - 0.00025 21.1 0.3 0.0026 17.8 0.1 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAM35736.1 - 0.029 13.0 7.5 0.027 13.0 2.6 3.3 4 1 0 4 4 4 0 Adaptin N terminal region HEAT PF02985.22 GAM35736.1 - 0.076 13.3 11.7 1.3 9.5 0.4 5.8 6 0 0 6 6 6 0 HEAT repeat RPN2_C PF18004.1 GAM35736.1 - 0.15 12.0 0.3 0.3 11.0 0.3 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain FAM176 PF14851.6 GAM35736.1 - 0.21 11.3 0.9 0.46 10.1 0.9 1.5 1 0 0 1 1 1 0 FAM176 family Sec7_N PF12783.7 GAM35736.1 - 0.68 9.8 3.7 32 4.4 0.0 4.2 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Tom22 PF04281.13 GAM35736.1 - 0.75 9.6 2.7 1.9 8.3 2.7 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Pyr_redox_2 PF07992.14 GAM35737.1 - 1.6e-44 152.4 0.0 2.1e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM35737.1 - 6.4e-12 45.9 0.0 3.9e-10 40.1 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 GAM35737.1 - 3.2e-07 29.4 0.2 9.1e-07 28.0 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAM35737.1 - 1.1e-05 25.0 0.4 3.2e-05 23.5 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 GAM35737.1 - 1.2e-05 25.6 0.1 3.5e-05 24.2 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 GAM35737.1 - 0.0003 20.2 0.2 0.00069 19.0 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 GAM35737.1 - 0.0071 16.2 0.2 0.036 13.9 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain pair Pyr_redox_3 PF13738.6 GAM35737.1 - 0.013 14.8 2.3 0.29 10.3 1.9 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CLTH PF10607.9 GAM35738.1 - 3.1e-33 114.8 0.1 3.9e-33 114.4 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 GAM35738.1 - 5.8e-09 35.6 0.0 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 LisH PRK PF00485.18 GAM35739.1 - 4.1e-58 196.4 0.0 6.5e-58 195.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 GAM35739.1 - 3.5e-44 150.7 0.1 5.8e-44 150.0 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 GAM35739.1 - 6.9e-06 26.6 0.1 2.2e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain CPT PF07931.12 GAM35739.1 - 0.0016 18.3 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 GAM35739.1 - 0.0066 16.6 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAM35739.1 - 0.012 15.0 0.0 0.034 13.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 GAM35739.1 - 0.014 15.8 1.2 0.81 10.1 0.2 3.1 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAM35739.1 - 0.028 14.9 0.1 2.1 8.8 0.1 2.3 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 GAM35739.1 - 0.04 14.3 0.0 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 GAM35739.1 - 0.046 13.7 0.0 1.4 8.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Pribosyltran PF00156.27 GAM35739.1 - 0.063 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosyl transferase domain APS_kinase PF01583.20 GAM35739.1 - 0.084 12.8 0.1 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA PF00004.29 GAM35739.1 - 0.18 12.3 0.0 0.47 10.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NUC153 PF08159.12 GAM35740.1 - 4.9e-14 51.8 0.1 4.9e-14 51.8 0.1 3.8 4 0 0 4 4 4 1 NUC153 domain FNIP_N PF14636.6 GAM35741.1 - 7.3e-34 118.0 0.1 7.3e-34 118.0 0.1 4.3 4 2 1 5 5 5 1 Folliculin-interacting protein N-terminus IML1 PF12257.8 GAM35742.1 - 1.3e-110 369.0 0.0 1.9e-110 368.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 GAM35742.1 - 4.4e-27 93.9 0.4 9e-27 92.9 0.4 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Na_Ca_ex PF01699.24 GAM35744.1 - 3.3e-43 147.2 45.3 2.3e-24 86.1 17.9 2.8 2 1 1 3 3 3 2 Sodium/calcium exchanger protein BHD_2 PF10404.9 GAM35744.1 - 9.7 7.2 6.4 41 5.2 2.1 2.3 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 DUF4282 PF14110.6 GAM35746.1 - 0.033 14.9 0.1 0.61 10.9 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) PTS_EIIC PF02378.18 GAM35746.1 - 0.085 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC zf-C2HE PF16278.5 GAM35746.1 - 0.12 12.9 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger ATP-synt_B PF00430.18 GAM35747.1 - 0.066 13.3 15.1 0.093 12.8 15.1 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) HSP70 PF00012.20 GAM35747.1 - 0.09 10.9 10.3 0.1 10.8 10.3 1.0 1 0 0 1 1 1 0 Hsp70 protein Spc24 PF08286.11 GAM35747.1 - 0.42 10.9 4.4 0.62 10.3 4.4 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Oxidored_FMN PF00724.20 GAM35748.1 - 5.4e-44 150.8 0.0 7.9e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 GAM35748.1 - 0.0027 16.9 0.0 0.014 14.5 0.0 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) adh_short PF00106.25 GAM35749.1 - 3.9e-21 75.4 0.1 3.1e-11 43.1 0.0 3.1 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35749.1 - 8e-13 48.5 0.0 8.6e-09 35.3 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM35749.1 - 0.001 19.1 0.8 0.15 11.9 0.8 2.3 1 1 0 1 1 1 1 KR domain VirJ PF06057.11 GAM35749.1 - 0.019 14.9 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Wax2_C PF12076.8 GAM35749.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 WAX2 C-terminal domain Ubiq-assoc PF09145.10 GAM35749.1 - 0.19 11.7 0.1 6.6 6.8 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-associated Ubie_methyltran PF01209.18 GAM35750.1 - 1.4e-77 260.2 0.0 2.3e-77 259.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family p450 PF00067.22 GAM35750.1 - 1.8e-56 191.9 0.0 2.2e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.6 GAM35750.1 - 8.8e-16 58.4 0.0 2.8e-15 56.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM35750.1 - 7.5e-14 52.1 0.0 3.3e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM35750.1 - 3.8e-11 43.0 0.0 8.2e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM35750.1 - 1.2e-10 42.0 0.0 3.5e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM35750.1 - 3e-06 27.1 0.0 6.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 GAM35750.1 - 0.12 12.3 0.0 0.4 10.5 0.0 1.8 2 0 0 2 2 2 0 Hypothetical methyltransferase SIS PF01380.22 GAM35751.1 - 2.2e-12 47.0 0.1 8.7e-12 45.0 0.0 2.0 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 GAM35751.1 - 0.00022 21.2 0.6 0.0034 17.4 0.1 2.5 2 1 1 3 3 3 1 SIS domain Granulin PF00396.18 GAM35752.1 - 0.00072 19.8 2.8 0.00072 19.8 2.8 2.5 2 1 0 2 2 2 2 Granulin CTP_transf_like PF01467.26 GAM35753.1 - 3.8e-22 79.0 0.0 5.4e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like HECT PF00632.25 GAM35754.1 - 1.4e-74 251.4 0.0 3.1e-74 250.2 0.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 GAM35754.1 - 3.1e-05 23.8 6.1 0.034 14.2 0.1 5.9 5 1 1 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 GAM35754.1 - 8.7e-05 22.5 0.6 0.053 13.8 0.1 4.4 3 0 0 3 3 3 1 HEAT repeat UNC45-central PF11701.8 GAM35754.1 - 0.0024 17.8 1.4 3.8 7.4 0.1 3.5 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 GAM35754.1 - 0.0032 17.9 0.1 0.04 14.4 0.1 2.9 2 0 0 2 2 2 1 HEAT-like repeat RIX1 PF08167.12 GAM35754.1 - 0.0039 17.0 0.3 0.83 9.4 0.1 3.4 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 GAM35754.1 - 0.019 13.6 1.8 0.046 12.3 0.0 2.5 3 0 0 3 3 3 0 Adaptin N terminal region HEAT_2 PF13646.6 GAM35754.1 - 0.028 14.8 0.9 9.7 6.7 0.0 3.8 3 0 0 3 3 3 0 HEAT repeats FMO-like PF00743.19 GAM35755.1 - 2.9e-26 92.0 0.0 1.3e-16 60.1 0.0 2.8 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAM35755.1 - 1e-07 31.6 2.0 1.2e-05 24.8 0.2 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM35755.1 - 0.00011 21.6 0.0 0.046 12.9 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM35755.1 - 0.00046 20.2 0.0 0.0045 17.0 0.1 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 GAM35755.1 - 0.16 11.1 0.0 0.16 11.1 0.0 2.3 3 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) MSC PF09402.10 GAM35756.1 - 4.6e-100 335.4 0.0 6.4e-100 334.9 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 GAM35756.1 - 1.9e-12 46.7 0.1 3.8e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 HeH/LEM domain FliN_N PF16973.5 GAM35756.1 - 0.058 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal EF-G-binding_N PF07299.11 GAM35757.1 - 0.041 14.4 0.0 0.066 13.7 0.0 1.2 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal Hs1pro-1_N PF07231.12 GAM35757.1 - 0.1 12.4 0.0 0.26 11.0 0.0 1.6 1 1 1 2 2 2 0 Hs1pro-1 N-terminus ADH_zinc_N PF00107.26 GAM35758.1 - 2e-12 47.2 0.0 3.3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM35758.1 - 3.3e-09 36.6 0.0 6.3e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM35758.1 - 0.021 15.9 0.0 0.046 14.8 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase EspB_PE PF18625.1 GAM35758.1 - 0.099 13.1 0.2 0.5 10.9 0.1 2.0 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain ADH_N_2 PF16884.5 GAM35758.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase PP2C PF00481.21 GAM35759.1 - 1.1e-52 179.3 0.0 2e-52 178.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 GAM35759.1 - 6.6e-37 125.1 57.3 4.3e-10 39.2 1.2 10.9 6 4 3 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 GAM35759.1 - 4.4e-32 109.6 59.2 0.0002 21.7 2.7 11.8 8 3 1 11 11 11 9 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 GAM35759.1 - 8.4e-29 100.5 0.0 2.1e-28 99.2 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 GAM35759.1 - 2.5e-13 49.5 0.2 2.5e-13 49.5 0.2 2.3 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.6 GAM35759.1 - 1.6e-09 37.5 12.8 0.0035 16.8 0.4 4.9 2 1 3 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.6 GAM35759.1 - 8.1e-08 32.3 3.3 1.5 8.7 0.2 5.2 5 0 0 5 5 5 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 GAM35759.1 - 2.5e-05 24.2 53.2 2.2 9.2 0.0 15.0 16 0 0 16 16 16 3 Leucine Rich Repeat Glyco_hydro_16 PF00722.21 GAM35760.1 - 3.1e-42 144.0 4.4 4.8e-42 143.4 4.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MIP PF00230.20 GAM35761.1 - 2.2e-46 158.4 5.4 2.5e-46 158.2 5.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.16 GAM35762.1 - 2.6e-73 246.0 0.3 4.2e-73 245.3 0.3 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GAM35762.1 - 1.2e-66 224.8 0.0 1.6e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Methyltransf_23 PF13489.6 GAM35763.1 - 5.3e-23 81.7 0.0 7.8e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM35763.1 - 7.8e-09 36.1 0.0 3.7e-08 34.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM35763.1 - 1e-07 31.9 0.0 3.6e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM35763.1 - 4.1e-07 30.7 0.0 4e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAM35763.1 - 7.5e-06 25.5 0.0 2e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.12 GAM35763.1 - 8.9e-06 26.3 0.0 4.9e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 GAM35763.1 - 0.00011 21.3 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) CMAS PF02353.20 GAM35763.1 - 0.00033 20.1 0.0 0.001 18.4 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 GAM35763.1 - 0.00057 19.5 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 GAM35763.1 - 0.0096 16.0 0.0 0.013 15.6 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 GAM35763.1 - 0.015 14.6 0.0 0.025 13.8 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 GAM35763.1 - 0.081 12.2 0.0 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 GAM35763.1 - 0.22 11.2 0.0 0.42 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DnaJ PF00226.31 GAM35764.1 - 2.4e-19 69.2 2.1 4e-19 68.5 0.9 2.1 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.22 GAM35764.1 - 0.0017 18.1 0.4 0.0049 16.7 0.4 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Helicase_PWI PF18149.1 GAM35764.1 - 5.7 7.2 13.1 6.9 6.9 1.5 3.3 3 0 0 3 3 3 0 N-terminal helicase PWI domain LDB19 PF13002.7 GAM35765.1 - 6e-53 179.4 0.1 1.1e-52 178.5 0.1 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 GAM35765.1 - 9.1e-09 35.5 0.0 8.4e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain WD40 PF00400.32 GAM35767.1 - 1.4e-27 95.3 7.9 2.9e-06 27.9 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM35767.1 - 3.1e-06 27.4 0.1 2.4 8.5 0.0 4.8 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM35767.1 - 0.008 15.2 0.0 0.57 9.1 0.0 2.6 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAM35767.1 - 0.071 13.1 0.0 88 3.2 0.0 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Zn_Tnp_IS1595 PF12760.7 GAM35767.1 - 0.15 12.0 3.0 0.34 10.9 3.0 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain SRP9-21 PF05486.12 GAM35768.1 - 1.7e-31 108.4 7.4 4.9e-31 107.0 7.4 1.7 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ank_2 PF12796.7 GAM35769.1 - 9.5e-16 58.2 0.2 1.7e-15 57.3 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAM35769.1 - 3.3e-13 49.4 0.6 3.4e-07 30.4 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 GAM35769.1 - 3.8e-13 49.7 0.1 1.3e-11 44.7 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM35769.1 - 7.3e-13 48.5 1.1 1.9e-07 31.2 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM35769.1 - 1.1e-11 43.8 0.1 3.7e-05 23.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat bZIP_Maf PF03131.17 GAM35769.1 - 0.35 11.4 9.6 0.59 10.7 9.6 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor CCDC24 PF15669.5 GAM35770.1 - 0.56 10.1 5.8 0.46 10.3 1.6 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 24 family GTP_EFTU PF00009.27 GAM35771.1 - 6.4e-20 71.5 0.2 1.8e-19 70.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GAM35771.1 - 1.1e-07 32.2 1.6 6.7e-07 29.6 1.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 GAM35771.1 - 5.4e-05 23.5 0.0 0.00016 22.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.9 GAM35771.1 - 0.0019 17.9 0.3 2.2 8.0 0.1 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 GAM35771.1 - 0.0098 16.0 0.1 0.027 14.5 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM35771.1 - 0.014 15.3 0.1 4.6 7.1 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 GAM35771.1 - 0.046 13.8 0.5 0.36 10.9 0.1 2.3 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 GAM35771.1 - 0.066 13.4 0.1 2.7 8.2 0.1 2.7 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase LSM PF01423.22 GAM35772.1 - 7.2e-19 67.3 0.3 9.7e-19 66.8 0.3 1.2 1 0 0 1 1 1 1 LSM domain SH3_9 PF14604.6 GAM35772.1 - 1.7 8.6 4.2 5.3 7.0 0.0 2.8 3 0 0 3 3 3 0 Variant SH3 domain ATP13 PF12921.7 GAM35773.1 - 1.7e-23 82.7 0.0 5.2e-23 81.1 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.6 GAM35773.1 - 6.8e-15 54.9 0.0 1.2e-07 31.6 0.0 2.6 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 GAM35773.1 - 1.7e-10 40.9 0.0 8.1e-06 25.9 0.0 2.6 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.20 GAM35773.1 - 0.0012 19.0 1.3 0.016 15.4 0.0 3.3 4 0 0 4 4 4 1 PPR repeat PPR_long PF17177.4 GAM35773.1 - 0.043 13.2 0.0 4.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GAM35773.1 - 0.11 12.2 0.1 10 5.9 0.0 3.2 4 0 0 4 4 4 0 PPR repeat Fungal_trans_2 PF11951.8 GAM35774.1 - 1.1e-15 57.3 4.8 3.6e-13 49.1 0.3 2.5 2 1 0 2 2 2 2 Fungal specific transcription factor domain PIG-L PF02585.17 GAM35774.1 - 2.7e-15 57.1 0.0 5.5e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Zn_clus PF00172.18 GAM35774.1 - 3.7e-06 26.9 10.2 7.7e-06 25.9 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy_3 PF13640.6 GAM35775.1 - 0.039 14.8 0.0 0.071 14.0 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 GAM35776.1 - 2.7e-12 46.3 13.4 4e-12 45.7 13.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAM35776.1 - 5 6.8 11.7 0.028 14.2 2.0 2.2 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 ATG22 PF11700.8 GAM35777.1 - 9.7e-114 380.6 24.0 1.1e-113 380.4 24.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 GAM35777.1 - 1.6e-13 50.3 29.5 3e-05 23.1 7.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily VbhA PF18495.1 GAM35777.1 - 0.0014 18.5 0.1 0.0025 17.6 0.1 1.3 1 0 0 1 1 1 1 Antitoxin VbhA SHOCT PF09851.9 GAM35777.1 - 0.16 11.8 0.1 0.27 11.0 0.1 1.3 1 0 0 1 1 1 0 Short C-terminal domain SAYSvFN PF10260.9 GAM35777.1 - 8.2 6.4 7.1 0.46 10.4 0.5 2.5 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) AP_endonuc_2 PF01261.24 GAM35778.1 - 1.1e-33 116.5 0.0 5.8e-33 114.1 0.0 2.0 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DHquinase_I PF01487.15 GAM35778.1 - 5.7e-19 69.3 0.0 1.2e-18 68.2 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Abhydrolase_6 PF12697.7 GAM35778.1 - 9.7e-14 52.5 0.0 2.4e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Shikimate_dh_N PF08501.11 GAM35778.1 - 1.3e-13 50.9 0.0 4.1e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Abhydrolase_1 PF00561.20 GAM35778.1 - 1.5e-08 34.7 0.0 3.5e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Shikimate_DH PF01488.20 GAM35778.1 - 2.1e-07 31.1 0.0 6.1e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Hydrolase_4 PF12146.8 GAM35778.1 - 0.0011 18.4 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SKI PF01202.22 GAM35778.1 - 0.004 17.3 0.0 0.0092 16.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase PGAP1 PF07819.13 GAM35778.1 - 0.043 13.5 0.0 0.41 10.3 0.1 2.2 2 0 0 2 2 2 0 PGAP1-like protein F420_oxidored PF03807.17 GAM35778.1 - 0.045 14.3 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ser_hydrolase PF06821.13 GAM35778.1 - 0.066 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase DUF900 PF05990.12 GAM35778.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 GAM35778.1 - 0.09 12.3 0.3 0.25 10.8 0.1 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Shikimate_dh_N PF08501.11 GAM35779.1 - 5.1e-05 23.5 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 GAM35779.1 - 0.00056 20.0 0.1 0.001 19.1 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAM35779.1 - 0.021 15.1 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 GAM35779.1 - 0.075 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family SDH_C PF18317.1 GAM35779.1 - 0.096 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain GFO_IDH_MocA_C PF02894.17 GAM35780.1 - 2.4e-09 37.2 0.0 5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 GAM35780.1 - 5.9e-07 30.3 0.2 1.1e-06 29.5 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PglD_N PF17836.1 GAM35780.1 - 0.014 16.1 0.4 0.025 15.2 0.4 1.4 1 0 0 1 1 1 0 PglD N-terminal domain DapB_N PF01113.20 GAM35780.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sugar_tr PF00083.24 GAM35781.1 - 1.9e-96 323.7 22.9 2.2e-96 323.5 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM35781.1 - 2.5e-28 99.0 47.4 1.8e-22 79.7 14.9 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM35781.1 - 3e-05 22.7 1.8 3e-05 22.7 1.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Peptidase_M20 PF01546.28 GAM35782.1 - 4.2e-33 114.8 0.0 7.8e-33 113.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM35782.1 - 6.9e-16 58.1 0.0 1.3e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAM35782.1 - 0.054 13.2 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 DASH_Spc19 PF08287.11 GAM35783.1 - 0.015 15.2 4.9 0.038 13.9 4.9 1.6 1 0 0 1 1 1 0 Spc19 Ax_dynein_light PF10211.9 GAM35783.1 - 0.016 15.2 0.9 0.031 14.2 0.9 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain Amidohydro_2 PF04909.14 GAM35784.1 - 7.2e-25 88.3 0.0 1e-24 87.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 GAM35784.1 - 0.054 12.9 0.0 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 TatD related DNase Ferritin_2 PF13668.6 GAM35785.1 - 2.6e-18 66.5 0.1 5e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain OHCU_decarbox PF09349.10 GAM35786.1 - 1.8e-45 155.2 0.1 2.1e-45 155.0 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase adh_short_C2 PF13561.6 GAM35789.1 - 1.4e-49 168.8 0.0 1.7e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM35789.1 - 6.7e-41 139.9 0.0 7.8e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM35789.1 - 1.9e-08 34.4 0.0 2.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF5403 PF17395.2 GAM35789.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5403) FAD_binding_4 PF01565.23 GAM35790.1 - 1.9e-30 105.4 0.1 2.8e-30 104.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM35790.1 - 0.00016 21.7 0.2 0.00037 20.5 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 GAM35792.1 - 7.6e-35 120.5 24.3 7.6e-35 120.5 24.3 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM35792.1 - 1.4e-15 57.1 6.8 1.4e-15 57.1 6.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4179 PF13786.6 GAM35792.1 - 0.19 12.2 1.4 15 6.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Cofilin_ADF PF00241.20 GAM35793.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein TruB_N PF01509.18 GAM35794.1 - 2e-45 154.8 0.4 1.8e-44 151.7 0.0 2.5 3 0 0 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 GAM35794.1 - 2.7e-06 27.4 0.0 5.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Peptidase_M36 PF02128.15 GAM35794.1 - 0.0016 17.7 0.3 0.0024 17.1 0.3 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) TFB6 PF17110.5 GAM35794.1 - 0.39 10.4 3.9 0.91 9.2 3.7 1.7 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Neur_chan_memb PF02932.16 GAM35794.1 - 1.1 9.3 2.8 1.7 8.7 2.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.17 GAM35794.1 - 1.1 9.4 8.6 2.1 8.5 8.6 1.5 1 1 0 1 1 1 0 DDHD domain SelP_N PF04592.14 GAM35794.1 - 2.2 7.6 5.3 9 5.6 0.0 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Smg8_Smg9 PF10220.9 GAM35794.1 - 2.3 6.4 8.6 3.3 5.9 8.6 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Presenilin PF01080.17 GAM35794.1 - 4.6 5.9 10.8 5.9 5.5 10.8 1.1 1 0 0 1 1 1 0 Presenilin SURF2 PF05477.11 GAM35794.1 - 5.1 6.7 13.9 8.7 6.0 13.9 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SOBP PF15279.6 GAM35794.1 - 5.3 7.6 6.9 8.1 7.0 6.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.10 GAM35794.1 - 5.3 5.6 4.9 6.9 5.2 4.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cytomega_UL84 PF06284.11 GAM35794.1 - 7 5.0 5.9 0.66 8.4 1.0 1.7 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein DNMT1-RFD PF12047.8 GAM35795.1 - 0.0047 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain HCMV_UL124 PF17609.2 GAM35795.1 - 0.0092 16.2 0.3 0.019 15.2 0.3 1.5 1 0 0 1 1 1 1 Family of unknown function HpaP PF09483.10 GAM35795.1 - 0.02 15.1 0.1 0.21 11.9 0.0 2.4 2 0 0 2 2 2 0 Type III secretion protein (HpaP) Ebp2 PF05890.12 GAM35796.1 - 5.9e-97 324.4 14.0 5.9e-97 324.4 14.0 2.0 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Caldesmon PF02029.15 GAM35796.1 - 0.0073 15.1 36.6 0.011 14.5 36.6 1.2 1 0 0 1 1 1 1 Caldesmon SDA1 PF05285.12 GAM35796.1 - 0.34 10.3 45.4 0.023 14.1 40.5 1.6 2 0 0 2 2 2 0 SDA1 HSBP1 PF06825.12 GAM35797.1 - 7.6e-20 70.5 0.0 1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 GAM35797.1 - 0.0022 17.8 0.1 0.0089 15.9 0.1 1.9 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.12 GAM35797.1 - 0.0063 16.9 0.1 0.0097 16.3 0.1 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 GAM35797.1 - 0.049 13.7 0.0 0.057 13.5 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0184 PF03670.13 GAM35797.1 - 0.1 13.0 0.4 0.38 11.2 0.4 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Thioredoxin PF00085.20 GAM35798.1 - 9.9e-62 205.4 0.3 1.5e-30 105.2 0.0 2.5 3 0 0 3 3 3 2 Thioredoxin ERp29 PF07749.12 GAM35798.1 - 4.9e-25 88.3 0.2 9.6e-25 87.3 0.2 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 GAM35798.1 - 4.4e-22 78.6 0.8 1.6e-09 38.2 0.0 3.0 3 1 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 GAM35798.1 - 2.9e-17 62.9 0.0 3.2e-08 33.3 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 GAM35798.1 - 3.1e-12 46.7 0.9 0.00011 22.4 0.0 4.5 3 2 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 GAM35798.1 - 9.9e-12 44.9 0.0 8.9e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 GAM35798.1 - 4.5e-10 39.5 0.0 0.00067 19.6 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 GAM35798.1 - 2e-06 27.8 0.0 0.028 14.3 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein HyaE PF07449.11 GAM35798.1 - 2.5e-05 24.2 0.0 0.035 14.1 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 GAM35798.1 - 2.5e-05 24.0 0.1 0.19 11.4 0.0 2.5 2 0 0 2 2 2 2 Redoxin Thioredoxin_3 PF13192.6 GAM35798.1 - 0.00027 20.9 0.0 0.09 12.8 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_9 PF14595.6 GAM35798.1 - 0.00032 20.5 0.0 0.43 10.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 GAM35798.1 - 0.0009 19.4 0.3 2.9 8.2 0.2 3.0 2 1 0 2 2 2 2 Glutaredoxin Thioredoxin_4 PF13462.6 GAM35798.1 - 0.0014 18.8 1.4 2.6 8.2 0.1 3.5 3 2 2 5 5 5 2 Thioredoxin DUF836 PF05768.14 GAM35798.1 - 0.0092 16.4 0.0 0.18 12.2 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 GAM35798.1 - 0.034 13.9 0.9 13 5.5 0.0 3.6 3 2 2 5 5 5 0 DSBA-like thioredoxin domain MKT1_C PF12246.8 GAM35799.1 - 6.1e-77 258.1 0.0 1.2e-76 257.1 0.0 1.5 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 GAM35799.1 - 2.5e-30 104.7 0.0 5.2e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 GAM35799.1 - 5.6e-06 26.8 0.0 3.2e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 GAM35799.1 - 8.6e-05 22.8 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 XPG I-region DIOX_N PF14226.6 GAM35800.1 - 2.1e-21 76.8 0.0 3.5e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM35800.1 - 4e-15 56.1 0.0 3e-13 50.1 0.0 2.8 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 GAM35801.1 - 3.1e-39 132.2 19.6 1.3e-05 25.9 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM35801.1 - 9.7e-16 57.9 0.0 0.00032 20.9 0.1 5.2 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM35801.1 - 7.4e-05 22.7 0.0 0.15 12.0 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 GAM35801.1 - 0.0027 17.1 0.0 0.077 12.3 0.0 2.8 2 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 GAM35801.1 - 0.05 12.6 0.3 21 4.0 0.0 3.6 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Na_Ca_ex PF01699.24 GAM35802.1 - 4.9e-30 104.5 40.7 3.5e-15 56.3 13.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SelP_N PF04592.14 GAM35802.1 - 0.093 12.1 11.4 0.17 11.3 11.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIA PF03153.13 GAM35802.1 - 0.5 10.3 9.5 1.1 9.2 9.5 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PBP1_TM PF14812.6 GAM35802.1 - 7.7 7.0 7.0 1.7e+02 2.6 0.0 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Phosducin PF02114.16 GAM35803.1 - 3.3e-12 45.9 0.1 2.4e-09 36.5 0.0 2.5 3 0 0 3 3 3 2 Phosducin Clathrin_lg_ch PF01086.17 GAM35803.1 - 0.18 11.9 7.3 0.28 11.2 7.3 1.3 1 0 0 1 1 1 0 Clathrin light chain YEATS PF03366.16 GAM35804.1 - 2.4e-19 69.1 0.0 5.8e-19 67.8 0.0 1.6 2 0 0 2 2 2 1 YEATS family BET PF17035.5 GAM35804.1 - 1.5e-06 28.3 0.1 2.8e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Ran_BP1 PF00638.18 GAM35805.1 - 4.8e-49 165.7 1.7 8.4e-49 164.9 1.7 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 GAM35805.1 - 0.00022 21.1 0.2 0.0012 18.8 0.2 2.0 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 GAM35805.1 - 0.0015 18.8 0.1 0.0022 18.3 0.1 1.2 1 0 0 1 1 1 1 VID27 PH-like domain CK2S PF15011.6 GAM35805.1 - 0.11 12.4 0.6 0.19 11.6 0.6 1.3 1 0 0 1 1 1 0 Casein Kinase 2 substrate FAD_binding_3 PF01494.19 GAM35806.1 - 6.5e-18 65.1 0.0 1.2e-17 64.2 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM35806.1 - 3.4e-07 30.4 1.1 2.3e-06 27.8 0.8 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM35806.1 - 1.3e-06 28.2 5.3 1.9e-05 24.4 5.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM35806.1 - 1.8e-05 24.1 2.1 0.00015 21.1 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM35806.1 - 0.00026 20.2 2.8 0.00046 19.4 2.8 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 GAM35806.1 - 0.0023 17.9 0.5 0.24 11.4 0.7 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAM35806.1 - 0.0029 18.1 1.5 0.0097 16.4 1.5 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM35806.1 - 0.0029 16.4 1.8 0.0045 15.8 1.8 1.2 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 GAM35806.1 - 0.0035 16.7 0.2 1.3 8.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 GAM35806.1 - 0.0042 17.0 0.7 0.0073 16.2 0.2 1.7 2 0 0 2 2 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 GAM35806.1 - 0.0053 15.9 1.9 0.0082 15.3 1.9 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 GAM35806.1 - 0.011 15.0 0.5 0.021 14.1 0.5 1.4 1 0 0 1 1 1 0 Thi4 family SE PF08491.10 GAM35806.1 - 0.024 13.7 0.0 0.7 8.9 0.0 2.5 3 0 0 3 3 3 0 Squalene epoxidase Lycopene_cycl PF05834.12 GAM35806.1 - 0.032 13.3 0.5 0.19 10.7 0.6 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 GAM35806.1 - 0.12 12.4 0.4 0.26 11.3 0.4 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.14 GAM35806.1 - 0.12 11.2 3.5 0.56 9.0 1.9 2.1 1 1 0 2 2 2 0 Tryptophan halogenase NAD_binding_2 PF03446.15 GAM35806.1 - 0.13 12.4 0.1 0.38 10.9 0.1 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_3 PF13738.6 GAM35806.1 - 0.44 9.8 2.4 1.4 8.1 1.8 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 GAM35806.1 - 0.84 9.3 3.8 0.7 9.5 2.3 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PNP_UDP_1 PF01048.20 GAM35807.1 - 0.00036 19.8 0.3 0.00069 18.9 0.3 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily RexA PF15969.5 GAM35807.1 - 0.013 15.0 0.0 0.069 12.7 0.0 1.9 2 0 0 2 2 2 0 Intracellular sensor of Lambda phage, Abi component MMR_HSR1 PF01926.23 GAM35808.1 - 1.1e-11 44.8 0.0 3.9e-11 43.0 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 GAM35808.1 - 1.1e-09 37.9 0.0 2.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 GAM35808.1 - 7.8e-06 25.4 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 GAM35808.1 - 1.6e-05 24.9 0.0 3.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 GAM35808.1 - 5e-05 22.7 0.0 9.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_18 PF13238.6 GAM35808.1 - 0.00056 20.4 0.0 0.0031 18.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 GAM35808.1 - 0.0071 16.4 5.0 0.042 13.9 0.5 2.8 2 1 1 3 3 3 1 Dynamin family DUF724 PF05266.14 GAM35808.1 - 0.01 15.7 0.3 0.018 14.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) AAA_29 PF13555.6 GAM35808.1 - 0.018 14.8 0.1 0.047 13.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 GAM35808.1 - 0.022 14.8 0.8 0.082 13.0 0.2 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 GAM35808.1 - 0.063 13.8 0.1 0.17 12.4 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 GAM35808.1 - 0.09 13.1 0.0 0.48 10.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 GAM35808.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 FeoB_N PF02421.18 GAM35808.1 - 0.15 11.6 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 GAM35808.1 - 0.2 11.4 3.1 5.2 6.8 0.5 3.2 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein APH PF01636.23 GAM35810.1 - 9.9e-12 45.3 0.5 1.4e-11 44.8 0.5 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM35810.1 - 6e-08 32.5 0.0 8.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 GAM35810.1 - 0.095 12.0 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.25 GAM35810.1 - 0.2 11.0 0.0 11 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain Prominin PF05478.11 GAM35811.1 - 0.31 8.9 2.3 0.14 10.1 0.2 1.4 2 0 0 2 2 2 0 Prominin Peptidase_C2 PF00648.21 GAM35812.1 - 5.8e-64 215.9 1.6 2.7e-44 151.4 0.5 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 GAM35812.1 - 0.056 13.7 1.2 0.69 10.2 0.0 2.8 3 0 0 3 3 3 0 Calpain large subunit, domain III Glyco_hydro_43 PF04616.14 GAM35813.1 - 7.3e-51 173.2 2.1 8.4e-51 173.0 2.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF2510 PF10708.9 GAM35813.1 - 6.2 6.7 7.3 0.53 10.1 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) Abhydrolase_3 PF07859.13 GAM35814.1 - 5e-07 29.8 0.2 6e-05 23.0 0.0 2.8 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM35814.1 - 0.0043 16.5 0.0 0.0072 15.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAM35814.1 - 0.0082 15.8 0.0 0.02 14.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold adh_short PF00106.25 GAM35815.1 - 6.2e-21 74.7 0.0 6.3e-20 71.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35815.1 - 1.3e-12 47.7 0.0 4.7e-12 46.0 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans_2 PF11951.8 GAM35815.1 - 7.3e-05 21.7 0.4 0.00011 21.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.10 GAM35815.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Cation_efflux PF01545.21 GAM35816.1 - 1.1e-39 136.2 3.7 1.7e-39 135.7 3.7 1.2 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 GAM35816.1 - 0.0069 15.6 0.2 0.016 14.4 0.2 1.6 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component CDH1_2_SANT_HL1 PF18375.1 GAM35817.1 - 0.064 13.9 0.0 0.09 13.5 0.0 1.2 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 Pkinase PF00069.25 GAM35818.1 - 1.7e-45 155.5 0.0 3.1e-23 82.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM35818.1 - 2.9e-13 49.7 0.0 8.5e-10 38.3 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase 2OG-FeII_Oxy_2 PF13532.6 GAM35819.1 - 4.6e-29 102.0 0.0 6.6e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Acyl-CoA_dh_1 PF00441.24 GAM35820.1 - 1.6e-31 109.6 1.6 3.4e-31 108.5 1.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAM35820.1 - 1.8e-20 73.7 0.1 4.2e-20 72.5 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAM35820.1 - 9.3e-20 70.6 0.0 1.9e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAM35820.1 - 5.8e-14 52.5 3.2 1.1e-13 51.6 1.5 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4600 PF15372.6 GAM35820.1 - 0.28 11.6 4.6 0.66 10.4 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) TolA_bind_tri PF16331.5 GAM35820.1 - 1.1 9.4 8.3 0.21 11.7 2.4 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation DivIC PF04977.15 GAM35820.1 - 2.8 7.8 5.3 0.89 9.4 1.3 2.1 2 0 0 2 2 2 0 Septum formation initiator Gly_transf_sug PF04488.15 GAM35821.1 - 1.1e-13 51.6 0.1 2.3e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 GAM35821.1 - 0.096 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein ABC2_membrane PF01061.24 GAM35822.1 - 1.2e-83 279.7 53.8 8e-47 159.4 21.7 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 GAM35822.1 - 6.1e-38 130.4 0.0 1.6e-17 64.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAM35822.1 - 2.1e-37 126.9 1.8 5.6e-31 106.3 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 GAM35822.1 - 1.1e-12 48.4 0.7 8.3e-12 45.6 0.5 2.6 2 0 0 2 2 2 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 GAM35822.1 - 6.3e-10 38.7 44.2 1.4e-06 27.6 12.4 2.7 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 GAM35822.1 - 1.2e-05 25.3 0.0 0.068 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAM35822.1 - 2.4e-05 24.3 0.1 9.2e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 GAM35822.1 - 0.00017 22.0 0.8 0.0078 16.6 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 GAM35822.1 - 0.00097 18.8 0.2 0.017 14.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAM35822.1 - 0.0032 17.2 0.1 0.58 9.9 0.0 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 GAM35822.1 - 0.01 16.0 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAM35822.1 - 0.011 16.0 0.6 1.6 9.0 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAM35822.1 - 0.017 14.9 0.0 0.27 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAM35822.1 - 0.03 14.9 0.0 0.56 10.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAM35822.1 - 0.03 14.2 0.1 0.57 10.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 GAM35822.1 - 0.032 14.5 0.2 0.091 13.0 0.2 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAM35822.1 - 0.048 13.7 0.3 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 GAM35822.1 - 0.096 12.3 0.6 0.74 9.4 0.4 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 GAM35822.1 - 0.13 12.8 1.2 2.7 8.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 GAM35822.1 - 0.73 10.2 0.0 0.73 10.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain RIFIN PF02009.16 GAM35824.1 - 0.0043 17.0 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 Rifin Orf78 PF06024.12 GAM35824.1 - 0.034 14.4 0.1 0.082 13.2 0.1 1.7 1 0 0 1 1 1 0 Orf78 (ac78) Use1 PF09753.9 GAM35824.1 - 0.08 12.7 1.4 0.19 11.4 1.2 1.7 1 1 0 1 1 1 0 Membrane fusion protein Use1 TMEM154 PF15102.6 GAM35824.1 - 0.16 11.9 2.9 0.65 9.9 1.0 2.5 2 0 0 2 2 2 0 TMEM154 protein family FAM176 PF14851.6 GAM35824.1 - 0.26 10.9 8.7 0.59 9.8 1.0 2.3 2 0 0 2 2 2 0 FAM176 family Voldacs PF03517.13 GAM35824.1 - 1.1 9.4 11.1 1.1 9.4 2.7 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling RRM_1 PF00076.22 GAM35825.1 - 1.5e-18 66.3 0.0 2.8e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trnau1ap PF17654.1 GAM35825.1 - 0.2 12.5 6.8 0.38 11.6 6.8 1.4 1 0 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins 6PGD PF00393.19 GAM35826.1 - 5.8e-128 426.3 0.0 7e-128 426.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 GAM35826.1 - 1.1e-50 171.9 0.0 1.7e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 GAM35826.1 - 0.078 13.6 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 GAM35826.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase AD PF09793.9 GAM35827.1 - 6.6e-28 96.7 0.0 1.1e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain Glyco_hydro_15 PF00723.21 GAM35828.1 - 2e-43 148.8 0.0 4.4e-42 144.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 TPT PF03151.16 GAM35829.1 - 1e-21 77.6 16.3 1.3e-21 77.3 16.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAM35829.1 - 1e-07 32.2 32.6 0.00089 19.4 11.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 GAM35829.1 - 0.00016 21.0 14.5 0.00025 20.4 14.5 1.2 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport Cwf_Cwc_15 PF04889.12 GAM35829.1 - 0.0052 16.6 0.8 0.0052 16.6 0.8 2.0 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein REV PF00424.18 GAM35829.1 - 0.024 14.7 2.2 0.063 13.3 2.2 1.7 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) PBP1_TM PF14812.6 GAM35829.1 - 0.6 10.5 6.0 2.1 8.7 6.0 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AP_endonuc_2 PF01261.24 GAM35830.1 - 1.9e-28 99.3 0.0 2.9e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.12 GAM35831.1 - 5.8e-44 149.0 0.1 1.1e-43 148.1 0.1 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 GAM35831.1 - 3.3e-14 52.8 0.0 6.6e-13 48.6 0.0 2.6 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 GAM35831.1 - 5.8e-08 32.4 0.0 3.6e-07 29.8 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Mad3_BUB1_I_2 PF17014.5 GAM35831.1 - 0.027 14.6 0.0 0.087 12.9 0.0 1.8 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein Peptidase_C15 PF01470.17 GAM35833.1 - 1.9e-10 41.3 0.0 0.011 15.9 0.0 3.1 2 1 0 3 3 3 3 Pyroglutamyl peptidase MOSC PF03473.17 GAM35834.1 - 5.8e-30 104.0 0.0 8.7e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 GAM35834.1 - 7.4e-20 71.0 0.0 1.4e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DNA_pol_phi PF04931.13 GAM35835.1 - 2.5e-252 839.4 19.6 3.5e-252 838.9 19.6 1.2 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 GAM35835.1 - 0.0015 18.1 29.7 0.0015 18.1 29.7 1.8 2 0 0 2 2 2 1 SDA1 Nop14 PF04147.12 GAM35835.1 - 0.007 14.6 24.9 0.014 13.6 24.9 1.5 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 GAM35835.1 - 0.084 11.1 15.1 0.2 9.9 15.1 1.7 1 0 0 1 1 1 0 CDC45-like protein GET2 PF08690.10 GAM35835.1 - 0.75 9.4 10.4 1.2 8.7 9.1 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 BUD22 PF09073.10 GAM35835.1 - 1.8 7.8 35.9 0.059 12.7 28.4 2.2 3 0 0 3 3 3 0 BUD22 PhoPQ_related PF10142.9 GAM35836.1 - 0.002 16.9 0.0 0.0031 16.2 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Hydrolase_4 PF12146.8 GAM35836.1 - 0.012 14.9 0.4 0.11 11.7 0.4 2.2 1 1 1 2 2 2 0 Serine aminopeptidase, S33 adh_short_C2 PF13561.6 GAM35837.1 - 2.9e-24 85.9 0.0 5.8e-24 84.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM35837.1 - 8.8e-24 84.0 0.0 1.2e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 GAM35837.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lipocalin_5 PF13924.6 GAM35837.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipocalin-like domain Cyclase PF04199.13 GAM35838.1 - 0.077 13.2 0.0 0.12 12.6 0.0 1.3 1 1 0 1 1 1 0 Putative cyclase NADH-u_ox-rdase PF10785.9 GAM35840.1 - 0.92 10.2 4.4 2.2 9.0 0.1 3.2 3 1 0 4 4 4 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Methyltransf_2 PF00891.18 GAM35841.1 - 4.1e-20 72.0 0.0 5.9e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain AMP-binding PF00501.28 GAM35842.1 - 2.1e-56 191.3 0.0 3.1e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 GAM35842.1 - 4.6e-28 98.9 0.0 1.7e-27 97.0 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 GAM35842.1 - 7.6e-09 35.8 0.0 1.6e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 GAM35842.1 - 0.0019 18.9 0.2 0.0039 17.8 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM35842.1 - 0.0054 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM35842.1 - 0.12 11.6 0.0 0.35 10.1 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 NAD_binding_2 PF03446.15 GAM35843.1 - 8e-21 74.8 0.0 1.4e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAM35843.1 - 2.9e-05 24.3 0.7 0.00018 21.8 0.7 2.0 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Cu-oxidase_3 PF07732.15 GAM35844.1 - 1e-44 151.4 3.1 2.2e-43 147.0 0.9 2.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 GAM35844.1 - 9.6e-34 116.8 0.6 4.6e-32 111.3 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAM35844.1 - 1.9e-31 108.6 7.0 1.1e-26 93.1 1.1 4.0 3 1 0 3 3 3 3 Multicopper oxidase RasGEF_N_2 PF14663.6 GAM35844.1 - 0.2 12.1 0.0 0.35 11.3 0.0 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Rhodanese PF00581.20 GAM35845.1 - 2.3e-14 53.8 0.0 6.8e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Cullin PF00888.22 GAM35846.1 - 5.4e-205 682.6 10.2 7e-205 682.3 10.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAM35846.1 - 1.3e-25 89.1 0.5 7.5e-25 86.8 0.1 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain zf-DNL PF05180.12 GAM35847.1 - 2.8e-27 94.4 0.3 4.8e-27 93.7 0.3 1.4 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 GAM35847.1 - 0.0013 18.4 0.1 0.0022 17.7 0.1 1.3 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_4 PF13717.6 GAM35847.1 - 0.012 15.5 0.3 0.083 12.8 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.18 GAM35847.1 - 0.026 14.4 0.8 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 GAM35847.1 - 0.037 14.1 0.5 0.065 13.4 0.5 1.4 1 0 0 1 1 1 0 Zinc ribbon domain zf-RING_7 PF02591.15 GAM35847.1 - 0.048 13.8 0.3 2 8.7 0.0 2.3 2 0 0 2 2 2 0 C4-type zinc ribbon domain HypA PF01155.19 GAM35847.1 - 0.13 12.3 0.4 0.21 11.6 0.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1 PF03811.13 GAM35847.1 - 0.15 11.8 0.7 0.15 11.8 0.7 1.9 2 0 0 2 2 2 0 InsA N-terminal domain DRIM PF07539.12 GAM35848.1 - 8.5e-185 615.6 0.5 8.5e-185 615.6 0.5 3.2 3 1 1 4 4 4 1 Down-regulated in metastasis HEAT PF02985.22 GAM35848.1 - 0.065 13.5 1.5 13 6.4 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat CwfJ_C_1 PF04677.15 GAM35849.1 - 8.6e-23 80.5 0.0 1.6e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 GAM35849.1 - 2.1e-14 54.2 0.1 4e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 RCR PF12273.8 GAM35850.1 - 6.9e-18 65.4 26.0 1.9e-17 64.0 26.0 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 GAM35850.1 - 0.0082 15.8 1.5 0.0082 15.8 1.5 1.4 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF2157 PF09925.9 GAM35850.1 - 0.013 15.3 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) LysE PF01810.18 GAM35850.1 - 0.022 14.2 0.3 0.027 13.9 0.3 1.1 1 0 0 1 1 1 0 LysE type translocator Phage_holin_5_2 PF16079.5 GAM35851.1 - 0.053 13.8 1.8 0.31 11.4 0.3 2.5 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V PGPGW PF09656.10 GAM35851.1 - 0.15 11.6 7.8 1.3 8.6 1.6 3.5 3 0 0 3 3 3 0 Putative transmembrane protein (PGPGW) Cation_ATPase_C PF00689.21 GAM35851.1 - 8.1 6.1 10.5 1.2 8.8 0.3 2.4 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Abhydrolase_1 PF00561.20 GAM35852.1 - 8.6e-09 35.4 0.1 3.8e-08 33.3 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM35852.1 - 1.2e-06 29.3 0.5 2.1e-06 28.5 0.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.16 GAM35852.1 - 0.00018 20.5 3.3 0.00028 19.9 3.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Hydrolase_4 PF12146.8 GAM35852.1 - 0.0011 18.4 0.0 0.0044 16.3 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 GAM35852.1 - 0.038 13.0 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase MFS_1_like PF12832.7 GAM35852.1 - 0.045 12.6 3.8 0.083 11.7 3.8 1.3 1 0 0 1 1 1 0 MFS_1 like family Sugar_tr PF00083.24 GAM35852.1 - 0.7 8.7 6.2 0.46 9.3 4.7 1.4 1 1 1 2 2 2 0 Sugar (and other) transporter Raptor_N PF14538.6 GAM35853.1 - 0.054 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Zn_ribbon_SprT PF17283.2 GAM35853.1 - 0.067 13.1 2.1 0.21 11.5 2.1 1.8 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 GAM35853.1 - 0.4 10.8 2.2 0.66 10.1 0.3 2.2 1 1 1 2 2 2 0 Zinc ribbon domain zf-LITAF-like PF10601.9 GAM35853.1 - 0.51 10.6 6.3 5.5 7.3 0.6 2.4 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 GAM35853.1 - 0.57 10.2 5.1 2.2 8.4 3.3 2.6 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 GAM35853.1 - 0.81 9.2 6.4 1.7 8.2 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Arf PF00025.21 GAM35854.1 - 1.2e-42 145.3 0.0 1.5e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GAM35854.1 - 1.5e-18 67.0 0.0 1.7e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM35854.1 - 1e-14 54.8 0.0 1.4e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAM35854.1 - 6.3e-08 32.7 0.0 1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAM35854.1 - 2.6e-06 27.0 0.0 3.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAM35854.1 - 5.4e-06 26.0 0.0 6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAM35854.1 - 0.00015 21.0 0.0 0.00065 19.0 0.0 1.9 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 GAM35854.1 - 0.0043 17.1 0.0 0.065 13.3 0.1 2.1 1 1 1 2 2 2 1 Dynamin family MMR_HSR1_Xtn PF16897.5 GAM35854.1 - 0.0046 17.0 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_22 PF13401.6 GAM35854.1 - 0.027 14.7 0.0 0.14 12.4 0.0 2.1 2 1 0 3 3 3 0 AAA domain FeoB_N PF02421.18 GAM35854.1 - 0.035 13.6 0.2 0.15 11.6 0.0 2.0 2 1 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAM35854.1 - 0.078 12.9 0.1 11 5.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF1979 PF09322.10 GAM35854.1 - 0.23 11.4 0.8 9.8 6.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) Peptidase_A4 PF01828.17 GAM35855.1 - 2.2e-76 256.0 13.9 2.6e-76 255.7 13.9 1.1 1 0 0 1 1 1 1 Peptidase A4 family RNA_pol_Rpb2_6 PF00562.28 GAM35856.1 - 1.2e-113 380.1 0.0 1.6e-113 379.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAM35856.1 - 1.6e-32 112.7 0.0 3.6e-32 111.5 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 GAM35856.1 - 2.1e-27 95.1 0.0 5.1e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 GAM35856.1 - 1.6e-25 88.9 0.0 3.1e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 GAM35856.1 - 5.6e-25 88.1 0.0 1.1e-24 87.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 GAM35856.1 - 5.1e-14 52.4 0.0 3.7e-13 49.7 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 Proteasome PF00227.26 GAM35857.1 - 2.7e-42 144.4 0.3 1.4e-32 112.8 0.1 2.1 2 0 0 2 2 2 2 Proteasome subunit Ank_2 PF12796.7 GAM35858.1 - 8.6e-33 112.8 0.1 2.9e-09 37.4 0.0 7.7 5 1 3 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM35858.1 - 9.1e-24 83.5 0.0 2.6e-06 27.8 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM35858.1 - 1.2e-22 79.6 1.2 2.3e-07 31.0 0.1 7.5 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM35858.1 - 2.3e-18 64.3 6.2 0.003 17.9 0.0 9.7 10 0 0 10 10 10 4 Ankyrin repeat Ank PF00023.30 GAM35858.1 - 8.9e-17 60.7 12.9 4.3e-05 23.8 0.1 8.9 9 1 0 9 9 9 4 Ankyrin repeat Sulfatase PF00884.23 GAM35859.1 - 3.7e-49 167.8 0.0 1e-35 123.6 0.0 2.2 1 1 1 2 2 2 2 Sulfatase Phosphodiest PF01663.22 GAM35859.1 - 0.0037 16.9 0.1 0.01 15.4 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 GAM35859.1 - 0.0038 15.9 0.0 0.005 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4994 PF16385.5 GAM35859.1 - 0.0073 16.2 0.0 0.044 13.7 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function DUF1501 PF07394.12 GAM35859.1 - 0.026 13.6 0.1 0.042 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF4976 PF16347.5 GAM35859.1 - 0.037 14.3 0.0 0.096 13.0 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 GAM35859.1 - 0.087 13.6 0.0 0.32 11.8 0.0 1.9 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase Pil1 PF13805.6 GAM35860.1 - 2.6e-98 328.8 6.6 3.4e-98 328.3 6.6 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 Seryl_tRNA_N PF02403.22 GAM35860.1 - 0.067 13.4 3.8 0.17 12.1 3.8 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PRAP PF15314.6 GAM35860.1 - 0.12 12.8 0.1 2.2 8.8 0.1 2.7 2 0 0 2 2 2 0 Proline-rich acidic protein 1, pregnancy-specific uterine DUF86 PF01934.17 GAM35860.1 - 0.16 11.8 1.2 2.1 8.2 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF86 APG6_N PF17675.1 GAM35860.1 - 0.22 12.0 5.8 0.35 11.4 5.0 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region SF1-HH PF16275.5 GAM35860.1 - 6.8 7.1 10.5 0.55 10.6 4.1 2.3 2 1 1 3 3 3 0 Splicing factor 1 helix-hairpin domain F-box-like PF12937.7 GAM35861.1 - 0.0016 18.3 4.4 0.038 13.9 0.6 2.4 2 0 0 2 2 2 2 F-box-like F-box_4 PF15966.5 GAM35861.1 - 0.13 12.1 2.5 1.3 8.9 0.1 2.8 3 1 0 3 3 3 0 F-box F-box PF00646.33 GAM35861.1 - 0.41 10.6 6.0 3.6 7.6 0.9 2.7 2 0 0 2 2 2 0 F-box domain MFS_1 PF07690.16 GAM35862.1 - 6.7e-32 110.8 25.4 6.7e-32 110.8 25.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 GAM35862.1 - 0.046 12.6 7.4 0.0082 15.0 2.2 2.1 2 1 0 2 2 2 0 MFS_1 like family Acetyltransf_10 PF13673.7 GAM35863.1 - 8.6e-09 35.4 0.0 5.2e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM35863.1 - 2.3e-06 27.8 0.0 3.8e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM35863.1 - 4.6e-06 27.0 0.0 2.3e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM35863.1 - 0.0004 20.5 0.0 0.00088 19.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM35863.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein SWI-SNF_Ssr4 PF08549.10 GAM35864.1 - 3.3e-247 822.7 19.2 3.4e-231 769.8 3.2 2.2 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1750) Noelin-1 PF12308.8 GAM35864.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Neurogenesis glycoprotein TFIIA PF03153.13 GAM35864.1 - 0.33 10.9 3.2 0.11 12.5 0.4 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Methyltransf_23 PF13489.6 GAM35865.1 - 5e-19 68.7 0.0 7.4e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM35865.1 - 4.5e-10 40.1 0.0 1.8e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM35865.1 - 2.7e-08 33.7 0.0 0.0035 17.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAM35865.1 - 2.6e-06 28.1 0.0 3.6e-05 24.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM35865.1 - 9.9e-06 26.1 0.0 1.9e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAM35865.1 - 0.0012 18.3 0.0 0.0055 16.2 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 GAM35865.1 - 0.0094 16.1 0.0 0.021 14.9 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 GAM35865.1 - 0.025 13.9 0.0 0.19 11.0 0.0 2.3 3 1 0 3 3 3 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 GAM35865.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase p450 PF00067.22 GAM35866.1 - 1.6e-45 155.7 0.0 2.2e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 GAM35867.1 - 3.7e-94 315.7 0.0 4.6e-94 315.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM35867.1 - 2.6e-10 41.1 0.0 7.3e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.26 GAM35868.1 - 5e-15 55.6 0.0 9e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM35868.1 - 5.6e-11 43.6 0.0 1.4e-10 42.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM35868.1 - 3.8e-08 33.2 0.2 1.1e-05 25.3 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAM35868.1 - 0.0073 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Glu_dehyd_C PF16912.5 GAM35868.1 - 0.065 12.7 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DIOX_N PF14226.6 GAM35869.1 - 1.6e-28 99.8 0.0 2.2e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM35869.1 - 2.4e-22 79.3 0.0 6.6e-22 77.9 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 GAM35870.1 - 2.6e-29 102.3 60.6 3e-23 82.3 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM35870.1 - 8.1e-06 25.0 38.2 0.0012 17.8 14.7 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter TssN PF17555.2 GAM35870.1 - 0.0051 16.2 1.9 0.0051 16.2 1.9 2.6 2 1 1 3 3 3 1 Type VI secretion system, TssN DUF3577 PF12101.8 GAM35870.1 - 0.23 11.3 0.1 0.46 10.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) Myb_DNA-binding PF00249.31 GAM35871.1 - 7.8e-34 115.6 17.7 2.5e-11 43.6 3.7 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM35871.1 - 8.9e-27 93.1 9.0 4.3e-12 46.1 0.2 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAM35871.1 - 0.00025 20.9 1.2 0.0064 16.4 0.1 2.6 2 1 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 GAM35871.1 - 0.0097 15.9 0.3 6.9 6.7 0.0 3.6 1 1 1 3 3 3 1 SLIDE Atg29_N PF18388.1 GAM35871.1 - 0.042 13.7 9.2 1.2 9.0 0.5 3.3 3 0 0 3 3 3 0 Atg29 N-terminal domain SANT_DAMP1_like PF16282.5 GAM35871.1 - 0.15 12.2 1.5 3.4 7.9 0.1 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 GAM35871.1 - 0.27 11.4 6.0 2.1e+02 2.1 6.0 3.3 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Carn_acyltransf PF00755.20 GAM35872.1 - 3e-101 339.9 0.0 4e-101 339.5 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 GAM35872.1 - 5.9e-70 235.7 0.0 1.1e-69 234.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 GAM35872.1 - 1e-55 189.1 0.0 2.5e-55 187.8 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAM35872.1 - 5.2e-52 177.3 0.3 2.1e-51 175.3 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.10 GAM35872.1 - 1.9e-49 168.0 0.6 1.4e-48 165.2 0.1 2.6 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 GAM35872.1 - 1.2e-38 131.8 0.1 3.8e-38 130.1 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 GAM35872.1 - 2.8e-18 66.5 0.0 8.3e-18 65.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAM35872.1 - 3.6e-17 62.8 0.0 9.8e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 GAM35872.1 - 1.1e-11 45.2 0.0 4.2e-11 43.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM35872.1 - 1.1e-11 44.8 0.0 2.8e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM35872.1 - 4.4e-08 33.7 0.0 1.4e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 GAM35872.1 - 2e-07 30.7 1.0 3.8e-06 26.5 0.1 2.6 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 GAM35872.1 - 3.5e-07 30.5 1.1 1.1e-06 28.9 1.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 GAM35872.1 - 5.7e-07 29.4 0.0 2.2e-06 27.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 GAM35872.1 - 2.7e-06 27.0 0.1 7.3e-06 25.5 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N PF00107.26 GAM35872.1 - 0.00028 20.9 0.0 0.0019 18.2 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.18 GAM35872.1 - 0.00042 19.7 0.0 0.00097 18.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 GAM35872.1 - 0.0014 18.4 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase ADH_N PF08240.12 GAM35872.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.26 GAM35873.1 - 6.2e-73 245.5 0.1 1.3e-72 244.5 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAM35873.1 - 2.8e-35 120.9 0.0 5.6e-35 119.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain AMP-binding PF00501.28 GAM35873.1 - 8.4e-31 107.0 0.0 1.7e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 GAM35873.1 - 1.4e-27 95.9 7.9 2.9e-11 43.6 0.4 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site HTH_51 PF18558.1 GAM35873.1 - 1.4e-25 88.9 0.0 6.6e-25 86.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain NAD_binding_4 PF07993.12 GAM35873.1 - 1.1e-24 87.0 0.0 2e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PS-DH PF14765.6 GAM35873.1 - 7.5e-22 77.9 0.0 1.6e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAM35873.1 - 3.4e-19 69.5 0.0 2.9e-18 66.4 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain Methyltransf_12 PF08242.12 GAM35873.1 - 1.1e-12 48.5 0.0 4.9e-12 46.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.13 GAM35873.1 - 4e-12 46.5 0.0 1.4e-11 44.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Epimerase PF01370.21 GAM35873.1 - 1.8e-08 34.2 0.0 4.5e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 GAM35873.1 - 5.1e-08 32.9 0.0 2e-07 31.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM35873.1 - 2e-07 31.6 0.0 8.2e-07 29.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.7 GAM35873.1 - 2.4e-06 28.3 1.7 7.9e-06 26.6 1.7 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 GAM35873.1 - 4.2e-06 27.2 0.0 2.3e-05 24.8 0.0 2.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Peptidase_S9 PF00326.21 GAM35873.1 - 4.8e-06 26.2 0.0 0.0044 16.5 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thiolase_N PF00108.23 GAM35873.1 - 8.5e-05 22.0 0.1 0.00019 20.9 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.12 GAM35873.1 - 0.0011 19.6 0.0 0.0035 18.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM35873.1 - 0.0062 16.3 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thioesterase PF00975.20 GAM35873.1 - 0.0076 16.4 0.0 0.033 14.3 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain KR PF08659.10 GAM35873.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 GAM35873.1 - 0.054 12.6 0.0 0.29 10.2 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Hydrolase_4 PF12146.8 GAM35873.1 - 0.11 11.8 0.0 1.7 7.8 0.0 2.6 3 0 0 3 3 2 0 Serine aminopeptidase, S33 LIP PF03583.14 GAM35873.1 - 0.14 11.5 0.0 0.33 10.2 0.0 1.6 1 0 0 1 1 1 0 Secretory lipase GDP_Man_Dehyd PF16363.5 GAM35873.1 - 0.14 11.5 0.0 4.4 6.6 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase S100PBPR PF15427.6 GAM35873.1 - 0.15 11.3 0.1 0.31 10.3 0.1 1.4 1 0 0 1 1 1 0 S100P-binding protein Methyltransf_33 PF10017.9 GAM35873.1 - 0.17 11.0 0.0 0.44 9.6 0.0 1.6 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_2 PF00891.18 GAM35874.1 - 8.8e-22 77.4 0.0 1.4e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 GAM35874.1 - 0.001 19.0 0.5 0.0022 17.9 0.5 1.6 1 0 0 1 1 1 1 Dimerisation domain Ppx-GppA PF02541.16 GAM35875.1 - 3.6e-48 164.5 0.0 5.2e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Thi4 PF01946.17 GAM35876.1 - 3.8e-112 373.2 0.0 4.5e-112 373.0 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 GAM35876.1 - 9.3e-07 28.7 1.4 3.3e-06 26.9 1.2 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM35876.1 - 7.4e-05 22.9 0.4 0.00027 21.1 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAM35876.1 - 0.00073 18.7 0.3 0.0019 17.4 0.4 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAM35876.1 - 0.0023 17.2 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM35876.1 - 0.0024 17.9 0.9 0.0056 16.7 0.1 2.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 GAM35876.1 - 0.007 15.5 1.0 0.19 10.8 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 GAM35876.1 - 0.082 12.1 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 GAM35876.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM35876.1 - 0.2 10.5 0.2 0.29 10.0 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Exo_endo_phos PF03372.23 GAM35877.1 - 1.5e-11 44.3 0.0 2.2e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 GAM35878.1 - 2e-54 180.3 15.7 7.7e-11 42.4 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM35878.1 - 1.1e-17 64.1 0.0 0.0014 18.8 0.0 5.8 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM35878.1 - 5.5e-12 45.1 2.5 0.1 11.2 0.1 5.8 1 1 4 6 6 6 5 Nucleoporin Nup120/160 eIF2A PF08662.11 GAM35878.1 - 8.7e-07 29.0 0.0 0.029 14.3 0.0 2.5 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAM35878.1 - 8.9e-06 24.9 0.6 5.3 5.9 0.0 4.7 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAM35878.1 - 1.7e-05 24.3 0.0 0.0044 16.4 0.0 2.4 2 1 0 2 2 2 2 WD40-like domain VID27 PF08553.10 GAM35878.1 - 0.00072 18.7 0.0 0.045 12.8 0.0 3.2 1 1 3 4 4 4 1 VID27 C-terminal WD40-like domain Frtz PF11768.8 GAM35878.1 - 0.0079 14.6 0.0 0.045 12.1 0.0 1.9 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 GAM35878.1 - 0.088 12.1 0.6 19 4.4 0.0 3.3 1 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DLH PF01738.18 GAM35880.1 - 2.4e-11 43.6 0.0 2.5e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.8 GAM35880.1 - 5.3e-09 35.7 0.0 4.7e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAM35880.1 - 2.1e-08 33.9 0.0 0.00078 19.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 GAM35880.1 - 1.9e-07 31.0 0.0 3.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM35880.1 - 1.6e-05 24.7 0.1 6.6e-05 22.7 0.1 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM35880.1 - 5.6e-05 23.9 0.0 0.00026 21.7 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAM35880.1 - 6.6e-05 22.7 0.0 0.00022 21.0 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein BAAT_C PF08840.11 GAM35880.1 - 0.00019 21.4 0.0 0.00043 20.3 0.0 1.5 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ser_hydrolase PF06821.13 GAM35880.1 - 0.00044 20.1 0.0 0.00074 19.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_3 PF07859.13 GAM35880.1 - 0.00049 20.0 0.0 0.0056 16.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 GAM35880.1 - 0.0019 18.1 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) LIDHydrolase PF10230.9 GAM35880.1 - 0.0041 16.7 0.0 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 GAM35880.1 - 0.01 15.7 0.0 0.077 12.8 0.0 2.2 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 GAM35880.1 - 0.012 15.5 0.1 0.03 14.2 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) DUF676 PF05057.14 GAM35880.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.20 GAM35880.1 - 0.026 14.2 0.0 0.057 13.1 0.0 1.6 1 1 0 1 1 1 0 Putative esterase MoCF_biosynth PF00994.24 GAM35880.1 - 0.029 14.0 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Probable molybdopterin binding domain Glyco_hydro_cc PF11790.8 GAM35881.1 - 1e-60 205.3 1.9 1.2e-60 205.0 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RED_N PF07808.13 GAM35882.1 - 1.5e-09 37.8 5.1 1.5e-09 37.8 5.1 2.5 2 0 0 2 2 2 1 RED-like protein N-terminal region Dicty_REP PF05086.12 GAM35882.1 - 0.42 8.5 4.8 0.74 7.7 4.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GvpG PF05120.12 GAM35882.1 - 1.2 9.2 8.3 0.13 12.3 1.8 2.7 3 0 0 3 3 3 0 Gas vesicle protein G zf-UBR PF02207.20 GAM35883.1 - 3.2e-17 62.4 17.6 3.2e-17 62.4 17.6 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 GAM35883.1 - 0.017 14.9 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS SDA1 PF05285.12 GAM35883.1 - 0.2 11.1 5.8 0.38 10.1 5.8 1.3 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 GAM35883.1 - 1.6 7.7 12.7 4.7 6.2 12.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) UCR_UQCRX_QCR9 PF05365.12 GAM35884.1 - 5.8e-27 93.4 1.3 1e-26 92.6 1.3 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4203 PF13886.6 GAM35884.1 - 0.081 12.6 0.0 0.085 12.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Mago-bind PF09282.10 GAM35885.1 - 7.7e-14 51.3 2.4 1.4e-13 50.5 2.4 1.4 1 0 0 1 1 1 1 Mago binding RR_TM4-6 PF06459.12 GAM35885.1 - 7.3 6.3 11.6 8.3 6.1 11.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 GAM35885.1 - 9.2 4.9 7.9 10 4.8 7.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Amino_oxidase PF01593.24 GAM35886.1 - 6.3e-30 104.8 0.0 9.7e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM35886.1 - 7.8e-15 54.9 0.0 2.6e-14 53.2 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM35886.1 - 1.8e-06 27.8 0.0 6.6e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM35886.1 - 0.00024 20.4 0.1 0.025 13.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 GAM35886.1 - 0.0014 17.5 0.0 0.0023 16.8 0.0 1.2 1 0 0 1 1 1 1 MCRA family NAD_binding_9 PF13454.6 GAM35886.1 - 0.0024 17.9 0.1 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAM35886.1 - 0.0033 17.9 0.0 3.2 8.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM35886.1 - 0.0052 15.9 0.0 0.024 13.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.6 GAM35886.1 - 0.0077 15.4 0.0 0.13 11.3 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 GAM35886.1 - 0.0088 14.8 0.0 0.27 9.9 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 GAM35886.1 - 0.027 13.7 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 GAM35886.1 - 0.094 12.0 0.1 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 GAM35886.1 - 0.15 11.1 0.5 0.66 9.0 0.0 2.2 3 0 0 3 3 3 0 Glucose inhibited division protein A zf-CCCH_2 PF14608.6 GAM35887.1 - 1.1e-12 47.9 61.9 8.4e-05 22.9 14.8 5.5 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 GAM35887.1 - 0.026 14.8 0.1 0.06 13.7 0.1 1.6 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) p450 PF00067.22 GAM35888.1 - 8.8e-55 186.3 0.0 1.3e-54 185.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YukC PF10140.9 GAM35888.1 - 0.0012 17.7 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC GCV_T PF01571.21 GAM35889.1 - 5.2e-05 22.7 0.0 0.00031 20.2 0.0 2.0 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain DCP2 PF05026.13 GAM35890.1 - 7.6e-31 106.3 1.2 1.5e-30 105.4 1.2 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 GAM35890.1 - 1.5e-16 60.6 0.1 2.7e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain DUF5538 PF17692.1 GAM35890.1 - 2.9 8.0 11.9 2.2 8.4 0.5 3.6 2 1 1 3 3 3 0 Family of unknown function (DUF5538) DUF4112 PF13430.6 GAM35891.1 - 7.2e-36 122.6 0.3 9.2e-36 122.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) CTU2 PF10288.9 GAM35892.1 - 4.2e-09 36.6 3.2 1.1e-08 35.2 0.0 2.3 1 1 1 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 zf-ribbon_3 PF13248.6 GAM35892.1 - 0.023 14.1 3.7 0.099 12.1 1.8 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 GAM35892.1 - 2.1 8.4 7.0 0.61 10.2 0.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon Lung_7-TM_R PF06814.13 GAM35893.1 - 4.9e-72 242.7 17.8 5.9e-72 242.4 17.8 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GFO_IDH_MocA PF01408.22 GAM35894.1 - 4e-17 63.2 0.1 6.5e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAM35894.1 - 2.4e-05 24.3 0.0 5.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF1308 PF07000.11 GAM35895.1 - 1.9e-11 44.2 0.0 3.2e-10 40.2 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) DUF4407 PF14362.6 GAM35895.1 - 0.15 11.4 5.2 0.25 10.7 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SPT6_acidic PF14632.6 GAM35895.1 - 5.7 7.6 16.6 0.055 14.1 4.4 3.3 3 0 0 3 3 3 0 Acidic N-terminal SPT6 LRR_4 PF12799.7 GAM35896.1 - 0.00035 20.9 14.8 0.37 11.3 0.6 5.8 3 2 3 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAM35896.1 - 0.019 15.0 9.1 0.51 10.5 0.0 5.9 7 0 0 7 7 7 0 Leucine Rich repeat FYVE PF01363.21 GAM35896.1 - 0.034 14.3 0.5 0.13 12.4 0.5 2.0 1 1 0 1 1 1 0 FYVE zinc finger Pex19 PF04614.12 GAM35896.1 - 0.48 10.2 9.7 1.2 8.9 7.3 2.2 2 0 0 2 2 2 0 Pex19 protein family DUF4604 PF15377.6 GAM35896.1 - 0.57 10.6 16.7 0.91 9.9 16.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) CDC45 PF02724.14 GAM35896.1 - 4.5 5.5 10.7 6.3 5.0 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SNF2_N PF00176.23 GAM35897.1 - 2.1e-33 115.5 3.4 1.2e-25 90.0 0.3 2.9 3 1 1 4 4 4 2 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM35897.1 - 7.7e-17 61.6 0.0 4.2e-16 59.3 0.0 2.3 3 0 0 3 3 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 GAM35897.1 - 1.4e-06 28.0 8.6 2.6e-06 27.2 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 GAM35897.1 - 9.5e-05 22.5 0.0 0.00035 20.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 GAM35897.1 - 0.0002 20.4 0.1 0.00054 19.0 0.0 1.7 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 zf-RING_UBOX PF13445.6 GAM35897.1 - 0.0012 18.8 5.4 0.0026 17.8 5.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAM35897.1 - 0.0051 16.6 8.0 0.01 15.7 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM35897.1 - 0.0089 16.0 8.6 0.015 15.2 8.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAM35897.1 - 0.013 15.3 7.9 0.024 14.5 7.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM35897.1 - 0.014 15.7 9.9 0.03 14.7 9.9 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 GAM35897.1 - 0.021 14.9 7.9 0.039 14.1 7.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ERCC3_RAD25_C PF16203.5 GAM35897.1 - 0.04 13.1 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-RING_10 PF16685.5 GAM35897.1 - 0.057 13.6 3.4 0.12 12.5 3.4 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_Tnp_IS91 PF14319.6 GAM35897.1 - 0.1 12.6 2.9 0.25 11.4 2.9 1.6 1 0 0 1 1 1 0 Transposase zinc-binding domain zinc-ribbons_6 PF07191.12 GAM35897.1 - 0.96 9.5 4.6 1.8 8.6 4.6 1.4 1 0 0 1 1 1 0 zinc-ribbons Prok-RING_4 PF14447.6 GAM35897.1 - 2.2 8.2 8.9 4.2 7.3 8.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 C2 PF00168.30 GAM35898.1 - 1.7e-12 47.5 0.0 3.3e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF3530 PF12048.8 GAM35898.1 - 0.13 11.7 0.8 0.28 10.6 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) ArfGap PF01412.18 GAM35899.1 - 3.4e-34 117.4 0.0 1.7e-33 115.1 0.0 2.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 GAM35899.1 - 9e-23 81.2 14.6 1.7e-22 80.3 14.6 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 GAM35899.1 - 1.3e-11 44.9 2.1 1.3e-11 44.9 0.2 2.0 2 0 0 2 2 2 1 PH domain V_ATPase_I PF01496.19 GAM35899.1 - 3.9 5.3 7.9 0.27 9.1 2.3 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family YTH PF04146.15 GAM35900.1 - 2.8e-60 203.0 0.0 7.1e-60 201.7 0.0 1.7 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 GAM35900.1 - 6e-09 35.6 0.0 1.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM35900.1 - 0.0027 17.5 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif FAM176 PF14851.6 GAM35900.1 - 0.88 9.2 3.4 2.4 7.8 3.4 1.7 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 GAM35900.1 - 3.4 5.7 11.4 5 5.2 11.4 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 GAM35900.1 - 6.2 6.5 15.9 1.3 8.7 12.3 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GAM35900.1 - 6.8 6.0 13.5 12 5.2 13.5 1.3 1 0 0 1 1 1 0 SDA1 PI3_PI4_kinase PF00454.27 GAM35901.1 - 2.7e-37 128.9 0.0 3.3e-33 115.5 0.0 3.3 2 1 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAM35901.1 - 1.9e-24 86.1 0.2 4.5e-24 84.9 0.2 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 GAM35901.1 - 0.059 12.7 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Pkinase PF00069.25 GAM35902.1 - 8.7e-79 264.6 0.0 1.2e-78 264.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM35902.1 - 2e-39 135.4 0.0 2.9e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 GAM35902.1 - 2.6e-17 62.9 0.1 5.2e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 GAM35902.1 - 1.8e-12 47.2 0.0 5.7e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 GAM35902.1 - 6.3e-07 28.5 0.0 6.3e-07 28.5 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 GAM35902.1 - 2.5e-06 27.7 0.0 6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 GAM35902.1 - 0.00069 19.6 0.2 0.0022 17.9 0.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 GAM35902.1 - 0.0014 18.3 0.1 0.45 10.1 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 GAM35902.1 - 0.003 17.0 0.1 0.0059 16.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2961 PF11175.8 GAM35902.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) p450 PF00067.22 GAM35903.1 - 9.1e-74 248.9 0.0 1.1e-73 248.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IGR PF09597.10 GAM35904.1 - 2e-24 85.4 0.2 3.4e-24 84.7 0.2 1.4 1 0 0 1 1 1 1 IGR protein motif Pkinase PF00069.25 GAM35905.1 - 2.3e-63 214.1 0.0 2.7e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM35905.1 - 1.4e-33 116.3 0.0 1.9e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM35905.1 - 0.0019 17.6 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAM35905.1 - 0.15 12.0 0.1 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinesin PF00225.23 GAM35906.1 - 1.4e-97 326.6 0.9 2.6e-97 325.7 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAM35906.1 - 3.5e-23 82.2 0.0 1.2e-22 80.5 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding ECSIT_C PF14784.6 GAM35906.1 - 0.16 12.3 0.1 2.8 8.3 0.0 2.4 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein PKcGMP_CC PF16808.5 GAM35906.1 - 0.25 11.3 6.2 0.16 11.9 0.5 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase NodZ PF05830.11 GAM35907.1 - 0.037 12.8 0.0 0.4 9.5 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) DAGAT PF03982.13 GAM35908.1 - 5.4e-95 317.7 0.0 6.9e-95 317.4 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 GAM35908.1 - 0.0038 17.0 0.1 0.0096 15.7 0.1 1.6 2 0 0 2 2 2 1 Rer1 family G-patch PF01585.23 GAM35909.1 - 6.3e-05 22.8 2.0 0.00026 20.8 0.1 2.8 2 1 0 2 2 2 1 G-patch domain DUF4551 PF15087.6 GAM35909.1 - 0.9 8.3 11.8 0.97 8.2 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SRP-alpha_N PF04086.13 GAM35909.1 - 1 9.2 38.2 1.5 8.6 38.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal BSP_II PF05432.11 GAM35909.1 - 1.6 8.3 27.4 2.8 7.6 27.4 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Macoilin PF09726.9 GAM35909.1 - 6.3 5.2 26.8 8.2 4.8 26.8 1.1 1 0 0 1 1 1 0 Macoilin family DUF2151 PF10221.9 GAM35909.1 - 9.9 4.6 21.0 14 4.1 21.0 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator Syja_N PF02383.18 GAM35910.1 - 1.2e-72 245.0 0.0 1.6e-72 244.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 GAM35910.1 - 1e-05 25.2 0.1 1.9e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF346 PF03984.13 GAM35911.1 - 2.1e-16 59.4 44.1 9.3e-07 28.5 1.3 7.7 8 0 0 8 8 8 5 Repeat of unknown function (DUF346) Exo_endo_phos_2 PF14529.6 GAM35911.1 - 4.4 7.2 8.9 1.2 9.0 0.1 2.7 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase TGT PF01702.18 GAM35913.1 - 2.2e-135 451.4 0.0 2.5e-135 451.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase RTA1 PF04479.13 GAM35914.1 - 7e-66 221.8 8.8 7e-66 221.8 8.8 1.8 2 0 0 2 2 2 1 RTA1 like protein RTA1 PF04479.13 GAM35915.1 - 1.4e-56 191.4 11.8 1.6e-56 191.2 11.8 1.0 1 0 0 1 1 1 1 RTA1 like protein Wzy_C_2 PF11846.8 GAM35915.1 - 0.18 11.7 0.4 7.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF3754 PF12576.8 GAM35915.1 - 1.8 8.5 4.7 12 5.8 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) Zn_clus PF00172.18 GAM35916.1 - 0.017 15.3 4.8 0.029 14.5 4.8 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAM35916.1 - 0.036 12.9 0.3 0.07 11.9 0.3 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.21 GAM35917.1 - 1.7e-39 136.1 0.0 3.1e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 GAM35917.1 - 9.5e-37 126.9 0.7 1.1e-29 103.9 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 GAM35917.1 - 1.2e-24 86.2 0.1 2.3e-24 85.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_transf_28 PF03033.20 GAM35918.1 - 6.1e-22 78.2 0.0 1.4e-21 77.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 GAM35918.1 - 0.0028 16.5 0.0 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 GAM35918.1 - 0.0074 16.1 0.4 0.33 10.7 0.5 2.3 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 GAM35918.1 - 0.034 14.5 0.2 1.3 9.4 0.0 2.7 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain Bac_rhamnosid_C PF17390.2 GAM35919.1 - 6.5e-08 32.3 0.2 1.8e-07 30.8 0.1 1.7 1 1 1 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 GAM35920.1 - 2.3e-09 37.0 0.0 8.2e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 GAM35920.1 - 0.00023 20.1 0.1 0.00033 19.6 0.1 1.1 1 0 0 1 1 1 1 Trehalase MFS_1 PF07690.16 GAM35921.1 - 9.5e-42 143.2 50.6 5.9e-41 140.6 50.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM35922.1 - 0.00043 19.4 0.1 0.00067 18.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.21 GAM35923.1 - 6.8e-94 315.4 0.0 2.1e-81 274.2 0.0 2.3 2 1 0 2 2 2 2 Amidase DUF2486 PF10667.9 GAM35923.1 - 0.06 13.6 0.2 0.098 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Fungal_trans_2 PF11951.8 GAM35924.1 - 1.8e-09 36.9 0.8 3.2e-09 36.1 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM35924.1 - 0.00016 21.7 6.8 0.0004 20.5 6.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAC3_GANP PF03399.16 GAM35925.1 - 3.9e-24 85.5 1.6 3.4e-22 79.2 1.6 2.4 1 1 0 1 1 1 1 SAC3/GANP family SH3_1 PF00018.28 GAM35925.1 - 1.9e-22 78.6 0.0 1e-10 41.0 0.0 3.1 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 GAM35925.1 - 1e-14 54.1 0.1 1.9e-06 27.6 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 GAM35925.1 - 3.9e-12 46.2 0.0 1e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 GAM35925.1 - 6.3e-11 41.8 0.0 4.7e-06 26.2 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 GAM35925.1 - 8.9e-09 35.2 1.7 1.8e-08 34.2 1.7 1.6 1 0 0 1 1 1 1 PB1 domain CSN8_PSD8_EIF3K PF10075.9 GAM35925.1 - 0.0037 17.3 0.1 0.0076 16.2 0.1 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family EAP30 PF04157.16 GAM35926.1 - 1.2e-42 145.9 1.0 1.6e-42 145.4 1.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 GAM35926.1 - 1.2e-23 83.1 0.0 2e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 GAM35926.1 - 1.6e-23 81.8 1.7 1.6e-23 81.8 1.7 2.4 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 GAM35926.1 - 3.4e-05 23.8 3.6 0.0026 17.8 0.3 2.4 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 GAM35926.1 - 0.0022 17.3 0.9 0.0022 17.3 0.9 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DUF3646 PF12362.8 GAM35926.1 - 0.021 15.1 0.1 0.051 13.9 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal EutK_C PF16365.5 GAM35926.1 - 0.028 14.5 1.6 0.056 13.5 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilization protein EutK C-terminus DZR PF12773.7 GAM35926.1 - 0.51 10.4 4.2 0.91 9.6 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2_4 PF13894.6 GAM35926.1 - 8.7 7.5 6.8 69 4.7 0.3 3.4 2 1 1 3 3 3 0 C2H2-type zinc finger PHD_like PF12910.7 GAM35927.1 - 0.046 13.7 0.4 0.11 12.5 0.4 1.6 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system DUF948 PF06103.11 GAM35927.1 - 8.6 6.7 9.2 0.29 11.4 0.4 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Ank_3 PF13606.6 GAM35929.1 - 0.032 14.7 0.0 0.057 14.0 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.6 GAM35929.1 - 0.061 13.9 0.0 0.082 13.5 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF5491 PF17595.2 GAM35929.1 - 0.062 13.6 0.0 0.24 11.7 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5491) Ank_2 PF12796.7 GAM35929.1 - 0.13 12.8 0.0 0.15 12.7 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 GAM35930.1 - 2.1e-21 76.3 0.0 6.5e-07 29.9 0.0 5.8 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM35930.1 - 2e-15 55.3 1.0 0.00043 20.5 0.1 7.1 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.6 GAM35930.1 - 2.8e-13 50.1 0.1 0.00067 20.2 0.0 6.8 6 2 0 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 GAM35930.1 - 1.5e-12 47.3 0.0 0.0013 19.1 0.2 6.1 5 1 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 GAM35930.1 - 4.6e-12 45.9 1.7 0.016 15.5 0.1 6.7 5 2 3 8 8 8 3 Ankyrin repeats (many copies) F-box-like PF12937.7 GAM35930.1 - 1.4e-05 24.9 0.1 4.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAM35930.1 - 0.045 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 GAM35930.1 - 0.18 11.7 0.0 0.85 9.5 0.0 2.1 2 0 0 2 2 2 0 F-box IBR PF01485.21 GAM35931.1 - 2e-05 24.7 3.8 2e-05 24.7 3.8 4.8 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain FKBP_C PF00254.28 GAM35933.1 - 5.5e-22 77.9 0.0 6.9e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Inhibitor_I71 PF12628.7 GAM35933.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor PHP PF02811.19 GAM35934.1 - 8e-17 62.0 0.1 1.5e-16 61.1 0.1 1.5 1 1 0 1 1 1 1 PHP domain ATP19 PF11022.8 GAM35935.1 - 7.1e-28 96.8 0.1 8e-28 96.6 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit K DUF3360 PF11840.8 GAM35935.1 - 0.16 10.7 0.2 0.18 10.5 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) RRS1 PF04939.12 GAM35936.1 - 1.8e-58 196.9 2.6 2.3e-58 196.7 2.6 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.9 GAM35937.1 - 7.6e-101 337.4 0.0 9.5e-101 337.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Methyltransf_23 PF13489.6 GAM35938.1 - 8.5e-17 61.5 0.0 1.3e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM35938.1 - 1e-08 35.7 0.0 5.3e-08 33.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM35938.1 - 1.6e-07 31.2 0.0 6.1e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM35938.1 - 5.3e-07 30.3 0.0 1.1e-05 26.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM35938.1 - 0.0027 18.3 0.0 0.015 15.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAM35938.1 - 0.0033 16.9 0.0 0.01 15.3 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 GAM35938.1 - 0.014 14.9 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 GAM35938.1 - 0.033 14.3 0.0 0.069 13.3 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 GAM35938.1 - 0.065 12.6 0.0 0.53 9.6 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Cupin_2 PF07883.11 GAM35939.1 - 2.7e-07 30.2 0.2 4e-07 29.6 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 GAM35939.1 - 0.024 14.3 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 GAM35939.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Cupin SWIRM-assoc_1 PF16495.5 GAM35940.1 - 0.028 14.4 3.3 0.079 12.9 3.3 1.7 1 0 0 1 1 1 0 SWIRM-associated region 1 DivIC PF04977.15 GAM35940.1 - 0.13 12.0 2.5 2.4 8.0 0.6 2.8 2 0 0 2 2 2 0 Septum formation initiator PRIMA1 PF16101.5 GAM35940.1 - 0.18 11.8 4.7 0.52 10.4 4.7 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CtIP_N PF10482.9 GAM35940.1 - 5.3 7.1 8.7 0.42 10.7 2.9 2.2 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain SKG6 PF08693.10 GAM35941.1 - 6e-07 28.8 0.1 1.2e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CFEM PF05730.11 GAM35941.1 - 0.00026 21.0 6.9 0.00056 19.9 6.9 1.6 1 0 0 1 1 1 1 CFEM domain VSP PF03302.13 GAM35941.1 - 0.0078 15.1 0.7 0.0078 15.1 0.7 1.7 2 0 0 2 2 2 1 Giardia variant-specific surface protein Podoplanin PF05808.11 GAM35941.1 - 0.053 13.6 0.6 0.053 13.6 0.6 2.5 3 1 0 3 3 3 0 Podoplanin Stevor PF17410.2 GAM35941.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ADIP PF11559.8 GAM35941.1 - 1.1 9.3 8.4 2 8.5 8.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Gram_pos_anchor PF00746.21 GAM35941.1 - 4.9 7.2 5.6 0.65 10.0 0.4 2.4 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Transp_cyt_pur PF02133.15 GAM35942.1 - 2.5e-86 290.2 35.0 3e-86 289.9 35.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin YrzO PF14142.6 GAM35942.1 - 0.15 12.0 0.2 0.33 10.8 0.2 1.5 1 0 0 1 1 1 0 YrzO-like protein DUF917 PF06032.12 GAM35943.1 - 2.6e-107 358.7 0.0 1e-106 356.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 GAM35943.1 - 3.3e-37 128.3 4.8 5.4e-32 111.2 0.1 3.2 3 0 0 3 3 3 3 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GAM35943.1 - 6.4e-30 104.2 2.5 5.2e-24 84.9 0.0 3.6 3 0 0 3 3 3 3 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 GAM35943.1 - 5.7e-07 28.5 0.1 0.028 13.0 0.1 2.5 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 GAM35943.1 - 0.0072 15.8 0.0 0.0072 15.8 0.0 2.8 2 1 1 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 GAM35943.1 - 0.039 13.2 0.2 1.4 8.1 0.0 2.5 2 0 0 2 2 2 0 StbA protein FtsA PF14450.6 GAM35943.1 - 0.041 14.3 0.5 9.8 6.7 0.1 3.2 2 0 0 2 2 2 0 Cell division protein FtsA Thioredoxin PF00085.20 GAM35944.1 - 1e-16 60.7 0.0 1.2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 GAM35944.1 - 0.0038 17.0 0.0 0.0046 16.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 GAM35944.1 - 0.006 16.3 0.0 1.1 9.0 0.1 2.0 1 1 1 2 2 2 2 Redoxin Thioredoxin_2 PF13098.6 GAM35944.1 - 0.015 15.7 0.1 0.038 14.4 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.24 GAM35944.1 - 0.07 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Cas_APE2256 PF09651.10 GAM35944.1 - 0.18 11.7 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) Pept_tRNA_hydro PF01195.19 GAM35945.1 - 2.6e-16 60.1 0.0 5.7e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 Peptidyl-tRNA hydrolase BAR PF03114.18 GAM35946.1 - 8.4e-46 156.5 0.4 1e-45 156.2 0.4 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 GAM35946.1 - 0.0094 16.7 0.3 0.036 14.8 0.0 2.1 3 1 1 4 4 4 1 CP12 domain DUF3340 PF11818.8 GAM35946.1 - 0.022 14.9 0.8 0.029 14.5 0.8 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Pkinase PF00069.25 GAM35947.1 - 1.9e-48 165.1 0.0 2.8e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM35947.1 - 3e-27 95.5 0.0 4.1e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAM35947.1 - 0.0046 16.3 0.0 0.0092 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAM35947.1 - 0.0075 15.6 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAM35947.1 - 0.066 13.1 1.2 1.8 8.4 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family eIF-6 PF01912.18 GAM35948.1 - 4.1e-79 264.6 0.4 5.2e-79 264.2 0.4 1.1 1 0 0 1 1 1 1 eIF-6 family SRI PF08236.11 GAM35949.1 - 2.8e-20 72.3 15.6 9.4e-20 70.6 15.6 2.0 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 GAM35949.1 - 4.2e-17 63.0 0.7 4.2e-17 63.0 0.7 3.4 3 1 0 3 3 3 1 SET domain AWS PF17907.1 GAM35949.1 - 3.6e-12 46.1 11.2 3.6e-12 46.1 11.2 2.5 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 GAM35949.1 - 0.0003 20.8 0.1 0.00099 19.1 0.1 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.26 GAM35949.1 - 0.01 15.9 0.4 0.025 14.7 0.4 1.7 1 0 0 1 1 1 0 WW domain DUF4554 PF15091.6 GAM35949.1 - 4.8 6.0 5.3 9.2 5.0 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) AT_hook PF02178.19 GAM35950.1 - 0.0048 16.6 1.5 0.026 14.4 1.5 2.4 1 0 0 1 1 1 1 AT hook motif Pkinase PF00069.25 GAM35951.1 - 3e-57 194.0 0.1 5e-51 173.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM35951.1 - 1.8e-35 122.5 0.0 1.7e-33 116.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAM35951.1 - 2.5e-08 33.6 0.0 2.4e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAM35951.1 - 0.0016 18.4 0.0 0.0035 17.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAM35951.1 - 0.0041 15.9 0.3 0.027 13.3 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase Sybindin PF04099.12 GAM35952.1 - 1.1e-25 90.2 0.0 1.4e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 GAM35952.1 - 0.0032 17.6 0.1 0.0047 17.0 0.1 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Acetyltransf_3 PF13302.7 GAM35953.1 - 2.4e-16 60.6 0.0 3.6e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM35953.1 - 2e-15 57.1 0.0 2.6e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM35953.1 - 3.5e-06 27.4 0.0 4.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAM35953.1 - 5.2e-06 26.7 0.0 8.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM35953.1 - 6.9e-06 25.9 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 GAM35953.1 - 5.4e-05 22.9 0.0 0.00012 21.8 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM35953.1 - 0.0023 17.9 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PigN PF04987.14 GAM35954.1 - 8.7e-143 476.5 41.7 7.5e-107 358.0 22.6 2.7 2 1 1 3 3 3 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 GAM35954.1 - 1.4e-08 34.7 2.4 4.7e-07 29.7 2.4 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAM35954.1 - 8.2e-08 32.0 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Csm1 PF12539.8 GAM35955.1 - 3.8e-32 110.7 0.1 1.5e-31 108.9 0.1 2.0 2 0 0 2 2 1 1 Chromosome segregation protein Csm1/Pcs1 EzrA PF06160.12 GAM35955.1 - 0.00066 18.0 4.5 0.00094 17.5 4.5 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF4686 PF15742.5 GAM35955.1 - 0.0011 18.2 6.8 0.0018 17.5 6.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) Flagellin_C PF00700.21 GAM35955.1 - 0.0028 18.0 3.0 1.2 9.5 1.3 2.7 2 0 0 2 2 2 1 Bacterial flagellin C-terminal helical region Spc7 PF08317.11 GAM35955.1 - 0.0046 15.9 8.8 0.0099 14.8 8.8 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein APG6_N PF17675.1 GAM35955.1 - 0.018 15.6 10.3 0.018 15.6 10.3 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF445 PF04286.12 GAM35955.1 - 0.02 14.7 1.6 0.03 14.1 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) TMF_TATA_bd PF12325.8 GAM35955.1 - 0.032 14.5 1.9 0.032 14.5 1.9 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding PKcGMP_CC PF16808.5 GAM35955.1 - 0.035 13.9 4.6 0.055 13.3 0.7 3.1 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 GAM35955.1 - 0.041 14.2 8.7 1.2 9.6 0.2 3.3 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF3138 PF11336.8 GAM35955.1 - 0.049 12.2 3.4 0.076 11.6 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) AAA_13 PF13166.6 GAM35955.1 - 0.058 12.0 7.6 0.099 11.3 7.6 1.4 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.12 GAM35955.1 - 0.07 13.6 1.1 0.77 10.3 0.8 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 GAM35955.1 - 0.09 12.8 4.0 0.22 11.6 4.0 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.9 GAM35955.1 - 0.09 12.6 1.0 2.2 8.2 0.0 2.7 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF3584 PF12128.8 GAM35955.1 - 0.092 10.3 13.7 0.16 9.5 13.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.11 GAM35955.1 - 0.16 11.7 4.4 3.7 7.3 2.6 2.5 3 0 0 3 3 2 0 Bacillus haemolytic enterotoxin (HBL) UPF0242 PF06785.11 GAM35955.1 - 0.17 12.0 10.3 0.038 14.1 5.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 GAM35955.1 - 0.21 11.6 17.9 0.037 14.1 12.6 2.4 2 1 0 2 2 1 0 Designed helical repeat protein 10 domain GAS PF13851.6 GAM35955.1 - 0.23 10.8 11.2 0.32 10.3 8.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 GAM35955.1 - 0.27 10.8 10.5 3.5 7.1 2.4 2.0 1 1 0 1 1 1 0 Intermediate filament protein ADIP PF11559.8 GAM35955.1 - 0.33 11.0 12.8 1.5 8.9 10.1 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Bap31_Bap29_C PF18035.1 GAM35955.1 - 0.35 10.9 9.8 78 3.4 1.2 4.3 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain GCN5L1 PF06320.13 GAM35955.1 - 0.4 10.8 4.2 1.1 9.5 3.9 2.0 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) V_ATPase_I PF01496.19 GAM35955.1 - 0.41 8.5 3.1 0.66 7.8 3.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CREPT PF16566.5 GAM35955.1 - 0.46 10.7 5.2 1.1 9.4 5.2 1.7 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour IFT20 PF14931.6 GAM35955.1 - 0.6 10.3 9.0 1.4 9.1 8.3 2.0 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF3450 PF11932.8 GAM35955.1 - 0.66 9.2 10.1 1.5 8.1 7.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Poxvirus_B22R PF04395.12 GAM35955.1 - 0.73 9.3 10.1 3.7 7.0 10.1 2.2 1 1 0 1 1 1 0 Poxvirus B22R protein AT_hook PF02178.19 GAM35955.1 - 0.87 9.7 18.1 6.2 7.1 2.4 4.0 3 0 0 3 3 3 0 AT hook motif Fib_alpha PF08702.10 GAM35955.1 - 0.94 9.7 5.8 2.8 8.1 5.7 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FliJ PF02050.16 GAM35955.1 - 1.1 9.5 8.2 3 8.1 8.2 1.7 1 0 0 1 1 1 0 Flagellar FliJ protein Lebercilin PF15619.6 GAM35955.1 - 1.2 8.8 12.4 1.6 8.3 7.9 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 GAM35955.1 - 1.5 8.8 4.2 3.5 7.7 3.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 GAM35955.1 - 1.8 7.8 3.8 3.1 6.9 3.8 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF641 PF04859.12 GAM35955.1 - 1.8 8.9 8.8 25 5.2 8.8 2.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) MPS2 PF17060.5 GAM35955.1 - 2 7.6 6.6 9.7 5.3 3.0 2.2 1 1 1 2 2 2 0 Monopolar spindle protein 2 IFT57 PF10498.9 GAM35955.1 - 2 7.3 10.9 0.034 13.1 3.5 1.8 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 COG2 PF06148.11 GAM35955.1 - 2.4 8.3 6.6 5.6 7.1 0.5 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 OmpH PF03938.14 GAM35955.1 - 2.4 8.5 13.2 34 4.8 13.2 2.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) PspA_IM30 PF04012.12 GAM35955.1 - 2.4 7.7 21.6 8.2 5.9 21.6 1.9 1 1 0 1 1 1 0 PspA/IM30 family Rootletin PF15035.6 GAM35955.1 - 2.8 7.9 13.8 0.35 10.9 9.4 1.7 2 0 0 2 2 1 0 Ciliary rootlet component, centrosome cohesion HAUS-augmin3 PF14932.6 GAM35955.1 - 2.8 7.4 12.6 3.6 7.1 11.4 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Prefoldin_2 PF01920.20 GAM35955.1 - 3.6 7.6 12.8 1.1 9.2 2.6 3.3 2 1 1 3 3 3 0 Prefoldin subunit Spc24 PF08286.11 GAM35955.1 - 4.5 7.6 11.8 0.088 13.1 1.3 3.1 2 1 1 3 3 2 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 GAM35955.1 - 4.8 7.3 15.8 0.45 10.6 10.1 2.3 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 GAM35955.1 - 5.9 5.9 10.7 1.4 8.0 7.4 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 GAM35955.1 - 8 6.5 16.1 0.092 12.8 2.7 3.3 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF2968 PF11180.8 GAM35955.1 - 8.1 6.0 13.6 0.67 9.6 8.0 2.1 3 0 0 3 3 2 0 Protein of unknown function (DUF2968) AAA PF00004.29 GAM35956.1 - 1.1e-37 129.5 0.0 3.2e-37 127.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM35956.1 - 1.3e-09 37.7 0.1 2.8e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAM35956.1 - 3.2e-06 27.6 1.5 0.00031 21.2 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 GAM35956.1 - 3.7e-06 27.0 0.0 8.7e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAM35956.1 - 1.7e-05 24.6 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAM35956.1 - 2.2e-05 24.5 0.1 0.0002 21.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAM35956.1 - 3.9e-05 23.8 0.0 9.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAM35956.1 - 0.00013 22.3 0.3 0.0061 16.8 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 GAM35956.1 - 0.00032 21.2 0.5 0.0032 18.0 0.0 2.5 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 GAM35956.1 - 0.00057 20.3 0.0 0.0016 18.8 0.0 1.9 1 1 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 GAM35956.1 - 0.00059 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAM35956.1 - 0.00096 18.6 0.1 0.0019 17.7 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GAM35956.1 - 0.0013 19.0 0.0 0.019 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAM35956.1 - 0.0015 18.7 0.0 0.0035 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 GAM35956.1 - 0.0017 17.8 0.1 3.2 7.1 0.0 3.0 2 1 0 3 3 3 2 Bacterial TniB protein AAA_25 PF13481.6 GAM35956.1 - 0.0024 17.5 0.1 0.033 13.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 GAM35956.1 - 0.0039 17.1 0.0 0.011 15.6 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain NACHT PF05729.12 GAM35956.1 - 0.0047 16.9 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Parvo_NS1 PF01057.17 GAM35956.1 - 0.0055 15.8 0.0 0.0091 15.1 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 GAM35956.1 - 0.013 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 GAM35956.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 GAM35956.1 - 0.014 15.9 0.0 0.04 14.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 GAM35956.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 GAM35956.1 - 0.018 14.2 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 GAM35956.1 - 0.032 13.8 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 GAM35956.1 - 0.042 13.7 0.0 0.2 11.5 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Guanylate_kin PF00625.21 GAM35956.1 - 0.05 13.3 0.0 0.66 9.6 0.0 2.7 2 1 1 3 3 3 0 Guanylate kinase TIP49 PF06068.13 GAM35956.1 - 0.06 12.5 0.1 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain TsaE PF02367.17 GAM35956.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 GAM35956.1 - 0.069 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 GAM35956.1 - 0.092 13.2 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 GAM35956.1 - 0.1 11.9 0.0 0.68 9.2 0.0 2.0 1 1 1 2 2 2 0 KaiC NB-ARC PF00931.22 GAM35956.1 - 0.11 11.7 0.1 0.64 9.2 0.0 2.2 3 0 0 3 3 3 0 NB-ARC domain AAA_21 PF13304.6 GAM35956.1 - 0.13 12.1 0.1 12 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Bac_DnaA PF00308.18 GAM35956.1 - 0.14 12.0 0.0 0.33 10.7 0.0 1.5 2 0 0 2 2 2 0 Bacterial dnaA protein Viral_helicase1 PF01443.18 GAM35956.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Hydin_ADK PF17213.3 GAM35956.1 - 0.27 11.5 1.8 14 5.9 0.0 2.8 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain LysM PF01476.20 GAM35957.1 - 0.019 15.0 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 0 LysM domain Fungal_trans PF04082.18 GAM35958.1 - 7.9e-35 120.2 0.0 1.8e-34 119.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAM176 PF14851.6 GAM35958.1 - 0.13 11.9 0.3 0.29 10.8 0.3 1.6 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 GAM35958.1 - 0.45 10.9 6.7 1.8 9.0 6.7 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cys_Met_Meta_PP PF01053.20 GAM35959.1 - 1.2e-141 471.7 0.0 1.4e-141 471.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAM35959.1 - 1.8e-05 23.9 0.0 3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 GAM35959.1 - 0.0001 21.6 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAM35959.1 - 0.00026 20.4 0.0 0.00082 18.8 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 GAM35959.1 - 0.00027 19.6 0.0 0.00092 17.8 0.0 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 GAM35959.1 - 0.016 14.5 0.0 0.041 13.2 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase GDC-P PF02347.16 GAM35959.1 - 0.039 12.8 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein RTA1 PF04479.13 GAM35960.1 - 9e-44 149.6 10.9 1.1e-43 149.2 10.9 1.2 1 0 0 1 1 1 1 RTA1 like protein MFS_1 PF07690.16 GAM35961.1 - 1.8e-23 83.0 22.1 1.8e-23 83.0 22.1 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM35961.1 - 4.7e-12 45.1 12.9 2.8e-11 42.6 12.9 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM35961.1 - 3e-09 36.2 15.6 3e-09 36.2 15.6 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM35962.1 - 9.9e-06 24.7 8.5 9.9e-06 24.7 8.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily XPC-binding PF09280.11 GAM35965.1 - 5.9e-24 83.6 18.0 9.5e-24 82.9 18.0 1.3 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 GAM35965.1 - 2e-23 81.9 2.1 2.1e-12 46.7 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 GAM35965.1 - 2.8e-23 81.4 0.1 4.7e-23 80.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAM35965.1 - 3.7e-08 33.1 0.2 6e-08 32.4 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAM35965.1 - 0.0013 19.0 0.2 0.0025 18.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAM35965.1 - 0.0049 17.0 0.0 0.0097 16.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 GAM35965.1 - 0.042 13.7 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Ubiquitin_2 PF14560.6 GAM35965.1 - 0.059 13.8 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 GAM35965.1 - 0.1 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CBM_4_9 PF02018.17 GAM35966.1 - 1.7e-07 31.5 4.4 2.3e-06 27.9 4.4 2.3 1 1 0 1 1 1 1 Carbohydrate binding domain Cadherin_tail PF15974.5 GAM35966.1 - 0.015 15.6 0.8 0.015 15.6 0.8 2.0 2 0 0 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region Glyco_transf_22 PF03901.17 GAM35968.1 - 3.7e-58 197.7 20.3 1.2e-33 117.0 9.5 2.1 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family Skp1 PF01466.19 GAM35969.1 - 2.4e-28 98.0 0.5 4.6e-28 97.1 0.5 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 GAM35969.1 - 2.4e-23 82.1 0.3 5.7e-23 80.9 0.2 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 GAM35969.1 - 0.081 13.2 0.0 1.1 9.6 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain ABC_membrane PF00664.23 GAM35970.1 - 6.8e-108 360.5 37.4 1.3e-55 189.0 18.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM35970.1 - 2e-70 235.6 0.0 2.4e-34 118.8 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAM35970.1 - 2.3e-14 53.4 0.0 3.1e-05 23.5 0.6 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAM35970.1 - 6e-09 36.5 5.8 0.00028 21.3 0.1 3.9 3 2 1 4 4 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAM35970.1 - 6.1e-07 29.5 0.0 0.11 12.3 0.0 3.5 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 GAM35970.1 - 6.9e-07 28.9 1.5 0.0024 17.5 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 GAM35970.1 - 9.5e-07 28.0 1.6 0.012 14.4 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA PF00004.29 GAM35970.1 - 1.9e-05 25.1 0.3 3 8.3 0.0 4.6 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM35970.1 - 3.7e-05 24.0 0.0 0.61 10.4 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.6 GAM35970.1 - 5.9e-05 22.7 0.6 0.083 12.4 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 GAM35970.1 - 0.00013 21.8 0.0 0.21 11.2 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 GAM35970.1 - 0.0008 19.2 5.6 0.58 9.9 0.0 4.3 5 0 0 5 5 5 2 AAA domain AAA_7 PF12775.7 GAM35970.1 - 0.00092 18.8 0.1 1.7 8.1 0.0 2.8 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_21 PF13304.6 GAM35970.1 - 0.0014 18.5 3.1 0.49 10.1 0.1 3.6 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 GAM35970.1 - 0.0022 17.2 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit Zeta_toxin PF06414.12 GAM35970.1 - 0.0028 17.0 1.2 2.2 7.5 0.0 3.3 3 1 0 3 3 3 2 Zeta toxin AAA_5 PF07728.14 GAM35970.1 - 0.005 16.8 0.1 4.4 7.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAM35970.1 - 0.0066 17.0 0.2 7.6 7.1 0.1 2.9 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 GAM35970.1 - 0.0077 16.2 0.0 0.62 10.0 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 GAM35970.1 - 0.011 15.9 0.0 6.7 6.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 GAM35970.1 - 0.013 15.8 0.3 0.59 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 GAM35970.1 - 0.03 13.9 0.1 4.7 6.8 0.0 2.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 GAM35970.1 - 0.032 14.1 0.0 2.2 8.2 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase Mg_chelatase PF01078.21 GAM35970.1 - 0.034 13.5 0.0 3.7 6.9 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 GAM35970.1 - 0.063 13.0 0.1 16 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 GAM35970.1 - 0.066 13.5 8.0 1.9 8.7 0.5 4.1 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 GAM35970.1 - 0.084 13.3 0.0 13 6.3 0.0 3.0 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 GAM35970.1 - 0.27 11.4 1.7 20 5.3 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF87 PF01935.17 GAM35970.1 - 0.32 11.0 2.0 9.7 6.2 0.0 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_23 PF13476.6 GAM35970.1 - 2 8.9 10.1 0.87 10.0 0.5 3.5 4 0 0 4 4 4 0 AAA domain Ytp1 PF10355.9 GAM35971.1 - 1.9e-72 243.8 24.6 2.8e-72 243.3 17.2 2.7 2 1 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.9 GAM35971.1 - 4.4e-32 110.0 6.3 4.4e-32 110.0 6.3 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) AWPM-19 PF05512.11 GAM35971.1 - 0.074 13.2 3.4 0.39 10.9 0.8 2.7 2 0 0 2 2 2 0 AWPM-19-like family DUF3180 PF11377.8 GAM35971.1 - 0.09 12.9 8.9 0.52 10.5 5.6 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF3180) ThiF PF00899.21 GAM35972.1 - 1.7e-30 106.2 0.0 2.6e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family MRC1 PF09444.10 GAM35973.1 - 8.9 6.8 8.5 0.31 11.5 0.7 2.6 3 1 0 3 3 3 0 MRC1-like domain Rrn6 PF10214.9 GAM35975.1 - 2.1 6.7 7.7 2.8 6.3 7.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CoA_binding PF02629.19 GAM35976.1 - 2.6e-26 92.2 3.7 2.8e-26 92.0 0.9 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 GAM35976.1 - 8e-23 81.0 0.3 1.2e-22 80.3 0.3 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 GAM35976.1 - 3e-08 33.6 0.0 5.5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 GAM35976.1 - 0.00075 20.0 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Radical_SAM_C PF16199.5 GAM35977.1 - 6.2e-32 109.5 0.0 1.3e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 GAM35977.1 - 2.2e-20 73.7 0.1 7e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 GAM35977.1 - 1.5e-10 41.3 0.1 2.8e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM35977.1 - 3.3e-06 27.0 0.1 1.2e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain AP_endonuc_2 PF01261.24 GAM35977.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Acetyltransf_7 PF13508.7 GAM35977.1 - 0.13 12.7 0.2 0.29 11.6 0.2 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4602 PF15375.6 GAM35978.1 - 1.4e-11 44.9 14.8 2.6e-11 44.0 14.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) YL1 PF05764.13 GAM35978.1 - 0.0071 16.5 12.0 0.01 16.0 12.0 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Ribosomal_L29e PF01779.17 GAM35978.1 - 0.65 10.4 3.8 15 6.0 2.6 3.1 2 1 0 2 2 2 0 Ribosomal L29e protein family STE PF02200.16 GAM35979.1 - 1.4e-56 189.6 0.1 2.8e-56 188.6 0.1 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 GAM35979.1 - 2e-11 43.7 10.7 5.1e-07 29.8 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM35979.1 - 6.3e-09 35.9 4.1 6.3e-09 35.9 4.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAM35979.1 - 2.9e-08 33.9 8.5 0.0002 21.9 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAM35979.1 - 8.3e-05 22.5 0.2 8.3e-05 22.5 0.2 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAM35979.1 - 0.0027 17.9 0.2 0.043 14.1 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding NOA36 PF06524.12 GAM35979.1 - 0.037 13.4 1.1 0.064 12.6 1.1 1.3 1 0 0 1 1 1 0 NOA36 protein zinc_ribbon_9 PF14369.6 GAM35979.1 - 0.092 13.0 0.2 0.23 11.7 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon zf-TRAF PF02176.18 GAM35979.1 - 0.17 12.6 2.6 0.3 11.8 2.6 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_2 PF12756.7 GAM35979.1 - 0.2 12.0 1.1 0.6 10.5 1.1 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 GAM35979.1 - 0.52 10.7 4.4 0.21 11.9 0.4 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 GAM35979.1 - 0.8 10.4 3.4 20 5.9 0.2 2.8 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 GAM35979.1 - 2.2 8.3 5.3 2.3 8.2 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type MFS_1 PF07690.16 GAM35980.1 - 4.6e-12 45.5 21.0 4.9e-11 42.2 11.0 3.0 3 0 0 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM35980.1 - 2.9e-09 36.0 8.5 6.2e-09 34.9 3.4 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.15 GAM35980.1 - 1.6e-05 24.1 1.2 3.8e-05 22.9 1.2 1.5 1 0 0 1 1 1 1 PUCC protein DAGK_prokar PF01219.19 GAM35980.1 - 0.062 13.1 1.5 4 7.3 0.0 3.2 3 0 0 3 3 3 0 Prokaryotic diacylglycerol kinase FAM176 PF14851.6 GAM35980.1 - 0.13 11.9 0.4 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 FAM176 family DUF2244 PF10003.9 GAM35980.1 - 2.8 7.6 5.0 0.51 10.0 0.6 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Na_H_Exchanger PF00999.21 GAM35981.1 - 2.4e-69 234.0 35.0 3.1e-69 233.6 35.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM PF03929.16 GAM35981.1 - 0.1 12.3 0.2 0.39 10.4 0.2 2.1 1 0 0 1 1 1 0 PepSY-associated TM region SNF2_N PF00176.23 GAM35982.1 - 1.6e-64 217.9 1.2 1.6e-64 217.9 1.2 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 GAM35982.1 - 1.4e-48 164.7 22.7 1.4e-48 164.7 22.7 4.8 4 1 1 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 GAM35982.1 - 2.1e-19 69.9 0.0 5.2e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM35982.1 - 1.5e-07 31.6 1.7 1.5e-06 28.3 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM35982.1 - 0.0023 17.7 0.0 0.0071 16.1 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 GAM35982.1 - 0.0066 15.6 0.0 0.065 12.4 0.0 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PD40 PF07676.12 GAM35983.1 - 1.7e-38 129.7 26.0 8e-06 25.7 0.3 9.5 9 0 0 9 9 9 8 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 GAM35983.1 - 1.8e-10 40.1 2.4 0.72 8.5 0.0 7.0 5 2 3 8 8 8 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF5050 PF16472.5 GAM35983.1 - 4.1e-05 23.0 0.2 0.065 12.5 0.0 4.6 4 3 0 4 4 4 1 Domain of unknown function (DUF5050) DUF3748 PF12566.8 GAM35983.1 - 0.045 13.7 2.6 61 3.6 0.0 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3748) WD40 PF00400.32 GAM35983.1 - 2.4 9.2 7.8 20 6.2 0.1 5.5 6 0 0 6 6 6 0 WD domain, G-beta repeat Aminotran_1_2 PF00155.21 GAM35984.1 - 3.7e-86 289.6 0.0 5.1e-86 289.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAM35984.1 - 3.3e-06 25.9 0.0 5.5e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 GAM35984.1 - 1.4e-05 24.6 0.2 2.5e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 GAM35984.1 - 5.7e-05 22.2 0.0 9.6e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF3405 PF11885.8 GAM35984.1 - 0.25 9.9 1.1 0.43 9.1 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3405) TB2_DP1_HVA22 PF03134.19 GAM35985.1 - 1e-19 70.2 7.0 1.2e-19 70.0 7.0 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family ATG101 PF07855.12 GAM35986.1 - 6.4e-55 185.4 0.0 7.4e-55 185.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Peroxin-3 PF04882.12 GAM35987.1 - 4.2e-165 550.3 1.9 5.7e-165 549.8 1.9 1.2 1 0 0 1 1 1 1 Peroxin-3 RNA_pol_I_A49 PF06870.12 GAM35988.1 - 1.1e-74 251.6 0.0 1.4e-74 251.3 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Ribosomal_L27e PF01777.18 GAM35988.1 - 0.14 12.5 0.4 1 9.7 0.0 2.4 2 1 0 2 2 2 0 Ribosomal L27e protein family Pro_CA PF00484.19 GAM35989.1 - 0.0095 16.2 0.2 0.049 13.9 0.2 1.9 1 1 0 1 1 1 1 Carbonic anhydrase MFS_1 PF07690.16 GAM35990.1 - 3.4e-32 111.8 45.8 5.8e-30 104.4 31.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF308 PF03729.13 GAM35990.1 - 9.1 6.7 26.7 4.9 7.5 0.2 4.8 3 1 0 4 4 4 0 Short repeat of unknown function (DUF308) p450 PF00067.22 GAM35991.1 - 2.4e-61 207.9 0.0 3.4e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 GAM35991.1 - 3.9e-07 30.5 0.4 2e-05 25.0 0.0 2.4 1 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 GAM35992.1 - 5.9e-20 71.6 0.0 8.8e-18 64.5 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM35992.1 - 1.4e-11 44.4 0.0 2.3e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM35992.1 - 0.00058 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM35992.1 - 0.07 12.6 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Csm1_B PF18211.1 GAM35992.1 - 0.074 12.9 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Csm1 subunit domain B Shikimate_DH PF01488.20 GAM35992.1 - 0.18 11.9 0.1 1 9.4 0.1 2.3 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Peptidase_S10 PF00450.22 GAM35993.1 - 3.6e-89 300.1 3.4 5.1e-89 299.6 3.4 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase PARP PF00644.20 GAM35994.1 - 1.9e-58 197.3 0.0 1e-57 194.9 0.0 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 GAM35994.1 - 9.2e-42 142.4 0.5 1.8e-41 141.4 0.5 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 GAM35994.1 - 8.1e-21 73.9 0.6 2.6e-20 72.3 0.6 1.9 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 GAM35994.1 - 3.5e-08 33.7 0.0 8.5e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GAM35994.1 - 9.1e-06 25.5 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 GAM35994.1 - 0.0032 17.8 0.0 0.0069 16.8 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Ysc84 PF04366.12 GAM35995.1 - 7.3e-47 158.3 0.3 1.3e-46 157.5 0.0 1.6 2 0 0 2 2 2 1 Las17-binding protein actin regulator Rpp20 PF12328.8 GAM35995.1 - 0.26 11.2 4.4 0.42 10.6 0.0 2.4 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P ETF PF01012.21 GAM35996.1 - 8.3e-44 149.6 0.9 1e-43 149.4 0.9 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DnaJ_C PF01556.18 GAM35997.1 - 4.5e-36 124.2 2.1 5.9e-36 123.8 2.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAM35997.1 - 2.3e-27 94.9 6.4 3.5e-27 94.3 6.4 1.3 1 0 0 1 1 1 1 DnaJ domain GATase PF00117.28 GAM35998.1 - 1.7e-46 158.4 0.0 2.2e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 GAM35998.1 - 1.9e-45 153.8 0.0 3.4e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 GAM35998.1 - 0.00039 20.2 0.5 0.0044 16.8 0.1 2.3 1 1 1 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 GAM35998.1 - 0.0086 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family PIG-X PF08320.12 GAM35999.1 - 4.7e-70 235.8 0.0 8.9e-70 234.9 0.0 1.5 1 0 0 1 1 1 1 PIG-X / PBN1 SNF2_N PF00176.23 GAM36000.1 - 1.3e-44 152.4 0.5 3e-44 151.2 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM36000.1 - 1.8e-20 73.3 0.1 6.4e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM36000.1 - 5.8e-05 23.1 0.0 0.00016 21.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAM36000.1 - 0.00051 19.3 0.1 0.0011 18.2 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 GAM36000.1 - 0.00071 19.3 0.0 0.12 12.0 0.0 2.5 2 0 0 2 2 2 2 SWI2/SNF2 ATPase BTB PF00651.31 GAM36000.1 - 0.043 14.0 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain GSH_synth_ATP PF03917.17 GAM36001.1 - 1.7e-137 458.2 0.0 1.9e-137 458.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 GAM36001.1 - 5.2e-29 100.7 0.0 1.3e-28 99.4 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic glutathione synthase Sugar_tr PF00083.24 GAM36002.1 - 1.3e-89 301.2 19.1 1.6e-89 300.8 19.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM36002.1 - 1.8e-12 46.8 43.3 1.9e-08 33.7 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GP24_25 PF17388.2 GAM36002.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 Bestrophin PF01062.21 GAM36004.1 - 2.2e-37 129.1 0.0 3.4e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel T6SS_VasE PF05936.12 GAM36004.1 - 0.0073 15.0 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE Transgly_assoc PF04226.13 GAM36005.1 - 0.012 15.8 2.2 0.042 14.1 0.2 2.7 2 0 0 2 2 2 0 Transglycosylase associated protein Cation_ATPase_C PF00689.21 GAM36005.1 - 1.7 8.3 21.6 1.5 8.5 1.4 3.1 1 1 2 3 3 3 0 Cation transporting ATPase, C-terminus OppC_N PF12911.7 GAM36005.1 - 6.8 6.8 7.2 18 5.4 0.0 3.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Aminotran_3 PF00202.21 GAM36006.1 - 1.5e-123 412.5 0.0 1.7e-123 412.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAM36006.1 - 0.093 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Spt4 PF06093.13 GAM36007.1 - 1e-32 112.0 0.2 1.2e-32 111.8 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TackOD1 PF18551.1 GAM36007.1 - 0.044 13.5 1.0 0.06 13.0 1.0 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Zn_ribbon_17 PF17120.5 GAM36007.1 - 0.22 11.2 2.8 0.44 10.2 2.8 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF89 PF01937.19 GAM36008.1 - 1.8e-133 444.9 0.0 2.5e-133 444.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 Metallophos PF00149.28 GAM36008.1 - 1.1e-32 114.3 0.1 8.2e-32 111.4 0.1 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 GAM36008.1 - 2.2e-32 111.2 1.8 3.8e-32 110.4 0.5 2.1 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 GAM36008.1 - 9.3e-13 47.4 1.2 0.00013 21.7 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM36008.1 - 1.6e-08 34.1 2.2 0.0051 16.8 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM36008.1 - 2.6e-05 23.8 2.1 0.051 13.3 0.6 3.0 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.6 GAM36008.1 - 9.8e-05 22.8 0.4 0.23 12.0 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM36008.1 - 0.001 19.7 2.0 2.8 8.7 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM36008.1 - 0.0023 18.0 0.0 0.015 15.5 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAM36008.1 - 0.005 17.4 0.1 1.4 9.8 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM36008.1 - 0.083 13.1 0.8 1.6 9.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Cytochrom_C550 PF14495.6 GAM36008.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c-550 domain Vps4_C PF09336.10 GAM36008.1 - 0.13 12.3 0.0 11 6.1 0.0 2.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain TPR_17 PF13431.6 GAM36008.1 - 0.16 12.4 0.2 2.8 8.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM36008.1 - 1 10.4 4.3 5.8 8.0 0.0 4.2 3 1 2 5 5 4 0 Tetratricopeptide repeat DUF5633 PF18656.1 GAM36008.1 - 1.3 9.0 4.8 2.1 8.3 1.1 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5633) Cut12 PF11500.8 GAM36009.1 - 7.2e-43 146.0 14.8 7.2e-43 146.0 14.8 3.1 2 1 0 2 2 2 1 Spindle pole body formation-associated protein DUF5471 PF17565.2 GAM36009.1 - 0.028 14.7 1.9 0.028 14.7 1.9 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5471) Spc7 PF08317.11 GAM36009.1 - 7 5.4 42.4 0.014 14.3 6.2 3.7 1 1 2 3 3 3 0 Spc7 kinetochore protein SpecificRecomb PF10136.9 GAM36009.1 - 9 4.5 9.5 11 4.2 9.1 1.4 1 1 0 1 1 1 0 Site-specific recombinase HGTP_anticodon2 PF12745.7 GAM36010.1 - 6.5e-86 288.1 0.0 6.5e-86 288.1 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 GAM36010.1 - 5.8e-78 261.9 0.0 3.5e-37 128.2 0.0 3.9 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAM36010.1 - 1.3e-40 139.3 0.0 1.6e-17 63.7 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 GAM36010.1 - 6.2e-18 65.2 0.6 1.9e-17 63.6 0.2 2.1 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 GAM36010.1 - 6.7e-13 48.6 0.2 9.7e-12 44.8 0.0 2.2 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 GAM36010.1 - 1.2e-07 31.9 2.7 5.5e-05 23.2 0.0 3.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family HGTP_anticodon PF03129.20 GAM36010.1 - 0.0019 18.3 0.0 0.0064 16.6 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain Kinase-like PF14531.6 GAM36010.1 - 0.011 15.1 0.0 0.99 8.7 0.0 2.8 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 GAM36010.1 - 0.023 14.3 0.1 0.53 9.9 0.0 3.2 4 0 0 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 HIF-1a_CTAD PF08778.10 GAM36010.1 - 0.079 12.6 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain Vps54_N PF10475.9 GAM36010.1 - 0.1 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex DUF1682 PF07946.14 GAM36010.1 - 3.3 6.8 10.7 5.7 6.1 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Torus PF16131.5 GAM36011.1 - 1.2e-46 157.9 2.0 7.8e-46 155.3 0.1 2.6 3 0 0 3 3 3 1 Torus domain RRM_1 PF00076.22 GAM36011.1 - 1.3e-08 34.5 0.0 2.6e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 GAM36011.1 - 0.00014 21.8 0.4 0.00014 21.8 0.4 1.7 2 0 0 2 2 2 1 Zinc finger domain Nup35_RRM_2 PF14605.6 GAM36011.1 - 0.0098 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 GAM36011.1 - 0.011 15.6 0.8 0.02 14.8 0.8 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Alpha_Helical PF18489.1 GAM36011.1 - 0.18 12.0 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 Alpha helical domain zf-CCCH_4 PF18044.1 GAM36011.1 - 0.59 10.0 2.0 1.2 9.1 2.0 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger MMR_HSR1_Xtn PF16897.5 GAM36012.1 - 7.4e-35 119.2 2.4 1.8e-34 117.9 0.8 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 GAM36012.1 - 4.4e-21 75.1 0.0 1.1e-20 73.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 GAM36012.1 - 2.1e-19 69.3 0.1 3.8e-19 68.5 0.1 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 GAM36012.1 - 5.8e-13 48.7 0.0 9.9e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAM36012.1 - 2.7e-05 24.3 0.2 0.045 13.8 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 GAM36012.1 - 0.042 12.8 0.3 0.15 11.0 0.1 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 GAM36012.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MCM PF00493.23 GAM36012.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain SNF2_N PF00176.23 GAM36013.1 - 2.6e-66 223.8 0.0 3.9e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 GAM36013.1 - 1.1e-17 63.8 0.0 2.2e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 GAM36013.1 - 1e-16 61.3 0.0 2.1e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 GAM36013.1 - 5.5e-10 38.9 6.9 1.2e-09 37.8 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM36013.1 - 1.9e-08 34.5 6.3 1.9e-08 34.5 6.3 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAM36013.1 - 1.3e-07 31.4 10.1 1.6e-07 31.0 5.3 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM36013.1 - 1.7e-07 31.0 7.2 4.3e-07 29.7 7.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAM36013.1 - 2.1e-07 31.1 4.3 5e-07 29.9 4.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAM36013.1 - 1.1e-05 25.4 2.9 1.1e-05 25.4 2.9 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.8 GAM36013.1 - 2e-05 24.3 4.2 7.8e-05 22.4 3.8 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 GAM36013.1 - 2.9e-05 23.9 5.5 6.4e-05 22.8 5.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAM36013.1 - 3e-05 24.1 5.8 6.3e-05 23.0 5.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAM36013.1 - 8.3e-05 22.4 4.9 0.00021 21.1 4.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 GAM36013.1 - 0.00085 19.0 0.6 0.011 15.4 1.4 2.6 2 0 0 2 2 2 1 RING-like zinc finger U-box PF04564.15 GAM36013.1 - 0.012 15.8 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 U-box domain zf-ANAPC11 PF12861.7 GAM36013.1 - 0.019 15.0 1.1 0.042 13.9 1.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HDA2-3 PF11496.8 GAM36013.1 - 0.077 12.1 0.0 0.39 9.8 0.0 2.1 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 GAM36013.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Vps39_2 PF10367.9 GAM36013.1 - 0.56 10.7 3.2 7.2 7.1 0.3 3.0 2 1 0 3 3 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_6 PF14835.6 GAM36013.1 - 0.99 9.3 6.0 0.1 12.5 1.3 1.8 2 0 0 2 2 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 GAM36013.1 - 1.7 8.5 3.4 3.6 7.4 3.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 GAM36013.1 - 8.5 6.6 7.8 1.2 9.4 3.5 1.8 2 0 0 2 2 1 0 zinc RING finger of MSL2 MBOAT_2 PF13813.6 GAM36014.1 - 1.3e-22 79.8 3.5 3.7e-22 78.4 3.5 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family TMEM208_SND2 PF05620.11 GAM36014.1 - 0.37 10.6 1.9 15 5.3 0.1 2.5 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 RIX1 PF08167.12 GAM36015.1 - 1.7e-62 210.5 1.5 3.5e-62 209.5 1.5 1.6 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis B12-binding PF02310.19 GAM36015.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain HEAT_EZ PF13513.6 GAM36015.1 - 0.27 11.8 1.3 40 4.9 0.0 4.1 5 0 0 5 5 5 0 HEAT-like repeat TPR_14 PF13428.6 GAM36016.1 - 4.6e-11 42.6 13.9 0.18 12.7 0.0 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM36016.1 - 2.6e-05 24.0 5.9 4 7.8 0.1 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM36016.1 - 0.00063 19.5 2.3 0.75 9.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM36016.1 - 0.0007 19.6 7.1 9.6 6.7 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM36016.1 - 0.0065 17.0 11.7 2.5 8.7 0.0 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM36016.1 - 0.0066 16.8 2.0 9.8 6.8 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM36016.1 - 0.0068 16.7 9.1 13 6.2 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2076 PF09849.9 GAM36016.1 - 0.35 10.9 4.5 0.16 12.0 1.5 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) TPR_7 PF13176.6 GAM36016.1 - 0.4 10.8 7.3 24 5.3 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAM36016.1 - 2.1 9.0 11.6 12 6.6 0.2 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM36016.1 - 6.3 7.7 5.4 99 3.9 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat NDUFA12 PF05071.16 GAM36017.1 - 4.3e-32 110.8 1.0 5.3e-32 110.5 1.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.6 GAM36018.1 - 4.7e-16 58.9 0.0 1.5e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 GAM36018.1 - 2.4e-09 37.0 0.4 0.00029 20.9 0.1 2.9 2 1 0 2 2 2 2 Phospholipase D Active site motif LTV PF04180.14 GAM36019.1 - 1.6e-126 423.2 14.0 1.8e-126 423.0 14.0 1.0 1 0 0 1 1 1 1 Low temperature viability protein MCLC PF05934.11 GAM36019.1 - 0.1 11.3 1.7 0.16 10.6 1.7 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) MMR_HSR1 PF01926.23 GAM36020.1 - 4.5e-16 58.9 0.1 1e-13 51.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM36020.1 - 2.4e-06 27.2 0.2 0.00012 21.6 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAM36020.1 - 4e-05 23.6 0.0 0.014 15.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 GAM36020.1 - 0.017 14.5 0.0 0.037 13.3 0.0 1.6 1 0 0 1 1 1 0 AIG1 family CvfB_WH PF17783.1 GAM36020.1 - 0.034 14.0 0.5 0.1 12.4 0.5 1.8 1 0 0 1 1 1 0 CvfB-like winged helix domain Dynamin_N PF00350.23 GAM36020.1 - 0.36 10.9 12.7 0.28 11.2 0.3 3.4 4 1 0 4 4 4 0 Dynamin family Glycos_transf_1 PF00534.20 GAM36021.1 - 3.4e-32 111.3 0.0 5.9e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAM36021.1 - 1.9e-29 102.8 0.0 3.5e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAM36021.1 - 8.3e-17 62.1 0.1 1.7e-16 61.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 GAM36021.1 - 9.1e-14 51.8 0.0 4.7e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 GAM36021.1 - 2.2e-05 24.7 0.0 6.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 UDPG_MGDP_dh_N PF03721.14 GAM36022.1 - 1.9e-45 154.8 0.0 3.7e-43 147.3 0.0 2.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 GAM36022.1 - 2.4e-31 107.8 0.0 4.3e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 GAM36022.1 - 5.3e-21 75.0 0.0 4.4e-17 62.4 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Pyr_redox_2 PF07992.14 GAM36022.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 GAM36022.1 - 0.028 14.7 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 GAM36022.1 - 0.048 13.5 0.0 0.13 12.1 0.0 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAM36022.1 - 0.066 13.4 0.0 1 9.5 0.0 2.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 GAM36022.1 - 0.096 12.2 0.1 0.22 11.1 0.1 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Stevor PF17410.2 GAM36022.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2278 PF10042.9 GAM36022.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) ApbA PF02558.16 GAM36022.1 - 0.18 11.5 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Acyl-CoA_dh_1 PF00441.24 GAM36023.1 - 1.5e-31 109.6 1.7 2.6e-31 108.9 1.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAM36023.1 - 6.3e-17 61.6 0.0 1.2e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAM36023.1 - 4.4e-16 59.5 0.1 9.2e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAM36023.1 - 1.3e-12 48.1 3.6 2.8e-12 47.0 3.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Spo12 PF05032.12 GAM36024.1 - 2.9e-16 59.1 1.2 2.9e-16 59.1 1.2 1.8 2 0 0 2 2 2 1 Spo12 family Sad1_UNC PF07738.13 GAM36025.1 - 1.3e-31 109.3 0.0 2.2e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal KRAP_IP3R_bind PF14722.6 GAM36025.1 - 0.02 14.6 0.0 0.089 12.5 0.0 2.1 2 0 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Muskelin_N PF06588.11 GAM36025.1 - 0.096 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Muskelin N-terminus Pkinase PF00069.25 GAM36026.1 - 2.8e-53 181.0 0.0 4e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM36026.1 - 1.2e-34 119.7 0.0 1.7e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM36026.1 - 2.1e-11 43.7 0.0 1.5e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 GAM36026.1 - 0.0082 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Zn_clus PF00172.18 GAM36027.1 - 6.3e-10 39.0 10.4 6.3e-10 39.0 10.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM36027.1 - 0.061 12.3 0.5 0.14 11.2 0.5 1.7 1 1 0 1 1 1 0 Fungal specific transcription factor domain RNase_PH PF01138.21 GAM36029.1 - 2.9e-31 108.7 0.0 4.7e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Hydantoinase_B PF02538.14 GAM36029.1 - 0.076 11.4 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase PEMT PF04191.13 GAM36030.1 - 9e-60 199.7 7.4 3.9e-36 123.6 0.6 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 GAM36030.1 - 0.033 14.7 0.0 1.5 9.4 0.0 2.4 2 0 0 2 2 2 0 SKICH domain HECW_N PF16562.5 GAM36030.1 - 0.056 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 ParA PF10609.9 GAM36031.1 - 3.4e-93 311.6 0.0 4e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAM36031.1 - 1.2e-09 38.3 0.0 6.3e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 GAM36031.1 - 1.3e-06 27.9 0.5 4.9e-05 22.7 0.1 2.6 1 1 2 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.6 GAM36031.1 - 1.4e-06 28.4 0.0 1.6e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 GAM36031.1 - 0.0013 18.3 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 GAM36031.1 - 0.0022 17.9 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GAM36031.1 - 0.0064 16.2 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 GAM36031.1 - 0.0077 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 GAM36031.1 - 0.015 15.2 0.1 0.038 13.9 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 GAM36031.1 - 0.035 14.1 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 GAM36031.1 - 0.044 13.4 0.1 0.083 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain MipZ PF09140.11 GAM36031.1 - 0.045 13.0 0.0 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 ATPase MipZ RNA_helicase PF00910.22 GAM36031.1 - 0.049 14.0 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 GAM36031.1 - 0.11 12.9 0.0 0.17 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 GAM36031.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 GAM36031.1 - 0.15 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 GAM36031.1 - 0.17 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Asp PF00026.23 GAM36032.1 - 2e-65 221.3 12.1 2.8e-65 220.8 12.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 GAM36032.1 - 1.4e-07 32.1 5.4 0.042 14.5 2.8 4.1 2 2 1 3 3 3 2 Aspartyl protease TAXi_N PF14543.6 GAM36032.1 - 1.7e-07 31.6 4.9 0.0044 17.3 1.3 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 GAM36032.1 - 0.0025 18.4 4.3 3.4 8.3 0.1 3.6 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 GAM36032.1 - 0.011 15.5 0.8 0.036 13.8 0.0 2.2 3 1 1 4 4 4 0 Xylanase inhibitor C-terminal tRNA_bind PF01588.20 GAM36033.1 - 6.9e-23 80.6 0.1 3.1e-21 75.3 0.1 3.1 3 1 0 3 3 3 1 Putative tRNA binding domain GST_C_2 PF13410.6 GAM36033.1 - 3.7e-06 26.9 0.0 7.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM36033.1 - 0.0048 17.1 0.0 0.0048 17.1 0.0 3.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAM36033.1 - 0.025 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM36033.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.3 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Presenilin PF01080.17 GAM36033.1 - 3.2 6.4 5.3 4.8 5.8 5.3 1.2 1 0 0 1 1 1 0 Presenilin HAGH_C PF16123.5 GAM36033.1 - 7.9 7.1 7.3 0.78 10.3 0.5 2.5 3 0 0 3 3 3 0 Hydroxyacylglutathione hydrolase C-terminus Anp1 PF03452.14 GAM36034.1 - 1.1e-112 375.7 0.1 2.2e-112 374.8 0.0 1.5 2 0 0 2 2 2 1 Anp1 Dcc1 PF09724.9 GAM36035.1 - 3.6e-21 75.8 0.0 5.3e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Acetyltransf_9 PF13527.7 GAM36036.1 - 0.00091 19.3 0.1 0.0021 18.2 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM36036.1 - 0.0012 19.2 0.0 0.0028 18.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM36036.1 - 0.018 15.0 0.0 0.063 13.3 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_10 PF13673.7 GAM36036.1 - 0.032 14.2 0.0 0.085 12.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM36036.1 - 0.032 14.5 0.0 0.09 13.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family IBR PF01485.21 GAM36037.1 - 7.4e-05 22.9 4.4 7.4e-05 22.9 4.4 3.9 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain HORMA PF02301.18 GAM36038.1 - 4.5e-08 33.0 0.0 6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Cas_Csm6 PF09659.10 GAM36038.1 - 0.2 10.4 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) IBN_N PF03810.19 GAM36039.1 - 6.1e-10 38.9 0.8 7.3e-08 32.2 0.1 4.2 3 2 1 4 4 4 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.15 GAM36039.1 - 0.00012 20.7 0.2 0.0004 19.0 0.1 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus RICTOR_N PF14664.6 GAM36039.1 - 0.00032 19.8 0.6 0.0025 16.9 0.0 2.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RIX1 PF08167.12 GAM36039.1 - 0.0012 18.6 0.1 0.0012 18.6 0.1 2.8 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis Xpo1 PF08389.12 GAM36039.1 - 0.0019 18.2 0.1 0.082 13.0 0.0 3.7 4 0 0 4 4 4 1 Exportin 1-like protein Arm PF00514.23 GAM36039.1 - 0.058 13.5 0.5 1.2 9.3 0.3 3.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Mo25 PF08569.11 GAM36039.1 - 0.1 11.9 0.1 11 5.2 0.0 2.6 2 0 0 2 2 2 0 Mo25-like PhyH PF05721.13 GAM36040.1 - 2.5e-08 34.4 0.0 5.6e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Het-C PF07217.11 GAM36041.1 - 7.7e-277 919.4 0.0 1.2e-276 918.7 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C CS PF04969.16 GAM36042.1 - 1.4e-06 29.3 0.1 2.4e-06 28.4 0.1 1.5 1 1 0 1 1 1 1 CS domain Ribosomal_L2_C PF03947.18 GAM36043.1 - 4.4e-41 140.0 5.5 4.4e-41 140.0 5.5 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 GAM36043.1 - 2.2e-14 53.2 0.1 5.7e-14 51.8 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF3093 PF11292.8 GAM36043.1 - 0.21 11.9 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Sugar_tr PF00083.24 GAM36044.1 - 5.9e-46 157.3 7.6 5.4e-38 131.0 2.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter FAA_hydrolase PF01557.18 GAM36044.1 - 6.2e-19 68.5 0.0 1.2e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.16 GAM36044.1 - 3.8e-12 45.8 4.6 5.2e-12 45.4 4.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM36044.1 - 2e-06 26.5 2.0 3e-06 25.9 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sulfatase PF00884.23 GAM36045.1 - 2.1e-30 106.2 0.0 2.5e-23 83.0 0.0 2.2 1 1 1 2 2 2 2 Sulfatase DUF229 PF02995.17 GAM36045.1 - 0.00032 19.4 0.0 0.00045 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 GAM36045.1 - 0.0013 19.0 0.2 0.003 17.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Sulfatase PF00884.23 GAM36046.1 - 1.2e-75 254.8 0.0 1.5e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 GAM36046.1 - 0.00016 21.5 0.0 0.0023 17.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF4976 PF16347.5 GAM36046.1 - 0.00088 19.5 0.0 0.0071 16.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 GAM36046.1 - 0.0014 19.4 0.1 0.097 13.4 0.1 2.4 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 GAM36046.1 - 0.025 13.2 0.0 0.044 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Fungal_trans PF04082.18 GAM36047.1 - 7.6e-17 61.2 0.0 1.1e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM36047.1 - 3.3e-07 30.3 6.9 6.4e-07 29.4 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPA_N PF01286.18 GAM36047.1 - 9.9 6.3 6.9 3.9 7.6 0.7 2.4 2 0 0 2 2 2 0 XPA protein N-terminal Glyco_hydro_3 PF00933.21 GAM36048.1 - 7.5e-48 163.5 0.0 9.9e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 GAM36048.1 - 3.3e-13 50.1 0.0 2.8e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Sulfatase PF00884.23 GAM36049.1 - 7.2e-63 212.8 0.0 9.6e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 GAM36049.1 - 1.2e-21 76.9 5.3 5.8e-21 74.7 5.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 GAM36049.1 - 6.5e-09 35.8 0.2 1.2e-07 31.7 0.2 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase ProRS-C_1 PF09180.11 GAM36050.1 - 1.1e-22 80.0 0.3 2.7e-22 78.7 0.3 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 GAM36050.1 - 8.4e-19 68.2 0.0 1.6e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAM36050.1 - 3.8e-12 46.2 0.0 1.7e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain Cpn60_TCP1 PF00118.24 GAM36051.1 - 1.5e-152 508.7 18.2 1.6e-152 508.6 18.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.32 GAM36052.1 - 7.3e-17 61.4 9.2 1.3e-05 25.8 0.2 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM36052.1 - 7.8e-08 32.5 0.0 0.00039 20.7 0.0 4.7 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM36052.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Dynamin_N PF00350.23 GAM36053.1 - 1.9e-14 54.1 0.0 1.9e-14 54.1 0.0 3.7 4 1 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.23 GAM36053.1 - 2e-05 24.7 0.0 0.00065 19.8 0.0 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 GAM36053.1 - 9.9e-05 22.9 0.6 0.00057 20.4 0.0 2.6 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 GAM36053.1 - 0.0006 19.8 0.0 0.0038 17.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 GAM36053.1 - 0.0031 16.8 0.1 0.02 14.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin TMF_TATA_bd PF12325.8 GAM36053.1 - 0.006 16.8 2.1 0.006 16.8 2.1 5.6 5 1 1 6 6 6 1 TATA element modulatory factor 1 TATA binding AAA_16 PF13191.6 GAM36053.1 - 0.0077 16.6 0.5 0.18 12.2 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain Chal_sti_synt_N PF00195.19 GAM36053.1 - 0.015 14.8 0.1 0.035 13.5 0.1 1.5 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain IIGP PF05049.13 GAM36053.1 - 0.02 14.0 0.0 0.065 12.3 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 GAM36053.1 - 0.052 12.9 0.0 0.22 10.8 0.0 2.1 1 0 0 1 1 1 0 AIG1 family AAA_14 PF13173.6 GAM36053.1 - 0.075 13.1 0.1 0.84 9.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAM36053.1 - 0.16 11.2 2.5 2.7 7.1 0.0 3.1 2 1 0 2 2 2 0 NB-ARC domain DNA_ligase_A_N PF04675.14 GAM36053.1 - 0.45 10.8 2.5 3.5 7.9 0.7 2.8 2 0 0 2 2 2 0 DNA ligase N terminus IATP PF04568.12 GAM36053.1 - 2.3 8.7 7.0 6 7.4 0.7 3.2 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP FOXP-CC PF16159.5 GAM36053.1 - 8.8 7.0 8.9 0.91 10.2 0.8 3.5 4 0 0 4 4 3 0 FOXP coiled-coil domain Fungal_trans PF04082.18 GAM36054.1 - 4.2e-12 45.7 6.1 2.8e-10 39.7 4.6 3.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain DAO PF01266.24 GAM36055.1 - 4.8e-47 161.2 0.1 5.5e-47 161.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM36055.1 - 8.2e-05 22.0 0.3 0.019 14.2 0.1 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM36055.1 - 0.00018 20.4 0.0 0.0066 15.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 GAM36055.1 - 0.00018 21.5 0.0 0.0052 16.8 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAM36055.1 - 0.00027 20.3 0.0 0.027 13.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM36055.1 - 0.00081 18.7 0.0 0.002 17.4 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 GAM36055.1 - 0.007 15.5 0.4 0.17 10.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GAM36055.1 - 0.01 16.0 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF5454 PF17535.2 GAM36055.1 - 0.044 13.2 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5454) Lycopene_cycl PF05834.12 GAM36055.1 - 0.046 12.8 0.1 0.079 12.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein MCRA PF06100.11 GAM36055.1 - 0.2 10.4 0.0 0.8 8.4 0.0 1.8 2 0 0 2 2 2 0 MCRA family AA_permease PF00324.21 GAM36056.1 - 3.8e-105 352.2 43.0 4.8e-105 351.9 43.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM36056.1 - 3.7e-26 91.9 48.1 4.8e-26 91.5 48.1 1.1 1 0 0 1 1 1 1 Amino acid permease HAD_2 PF13419.6 GAM36056.1 - 6.2e-06 26.4 0.0 9.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM36056.1 - 3.4e-05 24.2 0.0 0.00011 22.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NCE101 PF11654.8 GAM36056.1 - 0.064 13.0 0.2 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 p450 PF00067.22 GAM36057.1 - 8.6e-47 159.9 0.0 1.3e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 GAM36057.1 - 1.3e-08 34.8 11.0 1.3e-08 34.8 11.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.21 GAM36058.1 - 1.8e-37 129.4 0.0 2.1e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GAM36058.1 - 1.3e-05 24.4 0.0 1.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GAM36058.1 - 2e-05 23.3 0.0 2.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 GAM36058.1 - 0.014 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GAM36058.1 - 0.017 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Oxidored_FMN PF00724.20 GAM36059.1 - 7e-59 199.8 0.0 9.9e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Erf4 PF10256.9 GAM36059.1 - 9.7e-39 132.1 0.0 1.6e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Dus PF01207.17 GAM36059.1 - 0.019 14.1 0.0 0.065 12.3 0.0 1.8 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Adap_comp_sub PF00928.21 GAM36060.1 - 2.4e-83 279.5 0.0 3e-83 279.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAM36060.1 - 0.021 14.7 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain muHD PF10291.9 GAM36060.1 - 0.033 13.6 0.1 0.056 12.9 0.1 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Myb_DNA-bind_6 PF13921.6 GAM36061.1 - 0.00034 20.8 0.2 0.00061 20.0 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAM36061.1 - 0.0014 18.7 1.2 0.0023 18.1 1.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4589 PF15252.6 GAM36061.1 - 0.86 9.6 10.4 0.75 9.8 9.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4589) MFS_1 PF07690.16 GAM36062.1 - 6.9e-31 107.5 23.5 6.9e-31 107.5 23.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM36062.1 - 1.4e-05 24.2 24.9 3.6e-05 22.8 24.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter ThuA PF06283.11 GAM36063.1 - 8e-26 91.6 0.1 1e-25 91.2 0.1 1.0 1 0 0 1 1 1 1 Trehalose utilisation Amidohydro_2 PF04909.14 GAM36064.1 - 2.8e-34 119.2 0.3 3.2e-34 119.0 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 GAM36064.1 - 0.078 12.3 0.0 0.19 11.1 0.0 1.5 1 1 0 2 2 2 0 TatD related DNase Amidohydro_2 PF04909.14 GAM36065.1 - 0.00099 19.0 0.0 0.0011 18.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase p450 PF00067.22 GAM36066.1 - 5.6e-33 114.4 0.0 8e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 GAM36066.1 - 2.1e-08 34.2 7.3 4e-08 33.2 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM36066.1 - 0.004 16.2 0.2 0.0076 15.3 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_2 PF07992.14 GAM36067.1 - 0.04 13.1 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Say1_Mug180 PF10340.9 GAM36068.1 - 3e-07 29.7 0.0 6e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 GAM36068.1 - 7.4e-07 29.2 0.0 1.2e-06 28.6 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pkinase PF00069.25 GAM36069.1 - 4.3e-61 206.6 0.0 6e-61 206.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM36069.1 - 5e-27 94.8 0.1 2.1e-26 92.7 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase FHA PF00498.26 GAM36069.1 - 4.3e-11 43.0 0.1 9.7e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 GAM36069.1 - 8.4e-06 25.3 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM36069.1 - 8.5e-06 24.8 0.4 1.8e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 GAM36069.1 - 4.5e-05 22.6 0.2 9.2e-05 21.5 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAM36069.1 - 5.6e-05 22.6 0.0 7.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 GAM36069.1 - 0.0028 17.2 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Yop-YscD_cpl PF16697.5 GAM36069.1 - 0.024 15.0 0.0 0.17 12.2 0.0 2.3 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 GAM36069.1 - 0.12 12.3 0.1 0.12 12.3 0.1 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family bVLRF1 PF18826.1 GAM36070.1 - 2.3e-64 215.7 1.0 5.8e-64 214.5 1.0 1.7 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 GAM36070.1 - 8.6e-07 29.1 0.1 2.4e-06 27.7 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) zf-C2H2_2 PF12756.7 GAM36070.1 - 0.026 14.9 0.7 0.057 13.8 0.7 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ank_3 PF13606.6 GAM36070.1 - 0.21 12.2 0.2 0.97 10.2 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat DHDPS PF00701.22 GAM36071.1 - 5.8e-33 113.8 0.0 2.3e-32 111.9 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.8 GAM36072.1 - 3.5e-24 85.4 1.7 6.8e-24 84.4 1.7 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2841 PF11001.8 GAM36073.1 - 9.5e-43 145.2 0.0 1.4e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) ABC_tran PF00005.27 GAM36074.1 - 7.8e-52 175.4 0.1 4.9e-30 104.8 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAM36074.1 - 3.2e-44 151.6 10.1 4.1e-44 151.3 10.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 GAM36074.1 - 1.2e-11 44.5 4.4 0.00094 18.7 0.1 4.2 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GAM36074.1 - 6.2e-07 29.5 0.3 0.056 13.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 GAM36074.1 - 9.3e-07 29.4 0.9 0.029 14.7 0.4 3.0 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAM36074.1 - 1.6e-05 24.9 0.1 0.03 14.2 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 GAM36074.1 - 3.7e-05 23.4 0.1 0.095 12.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 GAM36074.1 - 6.3e-05 22.9 0.5 0.053 13.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 GAM36074.1 - 9.2e-05 22.2 2.4 0.038 13.7 0.0 3.6 4 1 0 4 4 2 1 AAA domain AAA_23 PF13476.6 GAM36074.1 - 0.00019 22.0 0.0 0.037 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 GAM36074.1 - 0.00035 20.7 0.6 0.061 13.4 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_15 PF13175.6 GAM36074.1 - 0.0011 18.7 0.1 0.21 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 GAM36074.1 - 0.0013 17.8 0.3 0.25 10.4 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein DUF87 PF01935.17 GAM36074.1 - 0.0046 17.1 0.3 0.84 9.7 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 GAM36074.1 - 0.0066 16.7 1.6 1.9 8.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAM36074.1 - 0.01 16.2 0.0 1.3 9.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.12 GAM36074.1 - 0.023 14.0 0.0 1.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 GAM36074.1 - 0.046 13.9 0.2 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 GAM36074.1 - 0.052 13.3 1.7 2.9 7.6 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein NACHT PF05729.12 GAM36074.1 - 0.09 12.7 3.9 0.28 11.1 0.1 3.0 3 0 0 3 3 3 0 NACHT domain AAA_27 PF13514.6 GAM36074.1 - 0.1 12.2 0.4 0.77 9.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 GAM36074.1 - 0.11 12.0 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 GAM36074.1 - 0.14 11.7 0.3 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 GAM36074.1 - 0.16 11.1 0.1 8.1 5.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_membrane PF00664.23 GAM36075.1 - 1.9e-38 132.7 6.6 1.9e-38 132.7 6.6 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region DUF4290 PF14123.6 GAM36075.1 - 0.11 12.0 0.9 0.54 9.8 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4290) Abhydrolase_9_N PF15420.6 GAM36075.1 - 4.4 7.3 10.2 13 5.7 6.8 2.7 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus SAC3_GANP PF03399.16 GAM36076.1 - 5e-106 354.4 2.1 8e-106 353.7 2.1 1.3 1 0 0 1 1 1 1 SAC3/GANP family PfkB PF00294.24 GAM36076.1 - 6e-07 29.1 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CN_hydrolase PF00795.22 GAM36076.1 - 1.6e-05 24.4 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CSN8_PSD8_EIF3K PF10075.9 GAM36076.1 - 5.9e-05 23.1 0.6 0.0002 21.4 0.1 2.0 3 0 0 3 3 3 1 CSN8/PSMD8/EIF3K family ssDNA-exonuc_C PF10141.9 GAM36076.1 - 0.053 13.2 0.2 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain HLH PF00010.26 GAM36077.1 - 2.5e-13 49.8 1.8 4.6e-13 48.9 1.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Propeptide_C1 PF08127.13 GAM36077.1 - 0.087 12.7 0.4 0.24 11.3 0.4 1.7 1 0 0 1 1 1 0 Peptidase family C1 propeptide DUF1281 PF06924.11 GAM36077.1 - 0.12 11.9 1.0 0.23 11.0 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DASH_Dad4 PF08650.10 GAM36077.1 - 0.12 12.4 1.5 0.67 10.0 0.3 2.5 1 1 1 2 2 2 0 DASH complex subunit Dad4 ABC_membrane PF00664.23 GAM36078.1 - 1.2e-63 215.3 37.5 6.6e-41 140.8 15.0 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 GAM36078.1 - 2.3e-43 148.0 0.5 3.6e-23 82.6 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAM36078.1 - 2.3e-05 24.0 7.6 0.0015 18.0 0.8 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GAM36078.1 - 2.5e-05 24.4 1.5 0.011 15.8 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 GAM36078.1 - 0.00017 21.2 0.1 0.056 13.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM36078.1 - 0.00029 20.8 0.6 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 GAM36078.1 - 0.003 17.6 1.0 0.49 10.4 0.0 3.0 2 1 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 GAM36078.1 - 0.0048 17.3 0.0 1.9 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 GAM36078.1 - 0.0049 16.4 0.1 0.26 10.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 GAM36078.1 - 0.0076 15.2 0.5 1.8 7.4 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Orthoreo_P10 PF07204.11 GAM36078.1 - 0.008 16.1 1.1 1.2 9.2 0.1 2.6 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 AAA_30 PF13604.6 GAM36078.1 - 0.016 14.9 0.5 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 GAM36078.1 - 0.021 14.5 0.1 6.2 6.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 GAM36078.1 - 0.021 14.2 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.6 GAM36078.1 - 0.032 13.8 0.0 6.5 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAM36078.1 - 0.037 14.3 0.6 8 6.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 GAM36078.1 - 0.048 13.1 0.3 3.4 7.1 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Roc PF08477.13 GAM36078.1 - 0.058 13.6 0.1 6.1 7.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 GAM36078.1 - 0.067 13.7 7.5 0.076 13.5 0.9 2.9 2 2 0 2 2 2 0 AAA domain DUF87 PF01935.17 GAM36078.1 - 0.069 13.2 4.9 0.31 11.1 0.0 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_18 PF13238.6 GAM36078.1 - 0.082 13.5 0.2 1.5 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 GAM36078.1 - 0.094 11.7 0.5 0.5 9.3 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 GAM36078.1 - 0.097 12.3 4.0 1.6 8.3 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 GAM36078.1 - 0.13 12.2 0.5 3.5 7.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.6 GAM36078.1 - 0.14 11.9 6.5 1.1 8.9 0.1 3.6 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAM36078.1 - 0.17 11.5 3.5 0.89 9.2 0.1 2.7 3 0 0 3 3 2 0 AAA ATPase domain TsaE PF02367.17 GAM36078.1 - 0.2 11.6 0.3 10 6.1 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 GAM36078.1 - 0.39 9.9 1.7 5 6.2 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 GAM36078.1 - 0.52 10.0 4.5 9 6.0 0.1 3.3 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein Cutinase PF01083.22 GAM36079.1 - 1.7e-44 151.9 0.4 2.1e-44 151.6 0.4 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 GAM36079.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.11 GAM36079.1 - 0.064 13.1 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF3405 PF11885.8 GAM36080.1 - 4.7e-174 579.8 1.0 6.2e-174 579.4 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Sec8_exocyst PF04048.14 GAM36081.1 - 1.4e-47 161.2 4.6 2e-46 157.4 2.1 2.8 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 GAM36081.1 - 1e-09 38.1 2.0 1.9e-09 37.3 2.0 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 GAM36081.1 - 0.00018 20.3 1.3 0.00035 19.3 1.3 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Dor1 PF04124.12 GAM36081.1 - 0.018 13.7 5.1 0.039 12.6 5.1 1.5 1 0 0 1 1 1 0 Dor1-like family Creatinase_N_2 PF16189.5 GAM36082.1 - 2.7e-53 180.4 0.1 4.1e-51 173.3 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 GAM36082.1 - 7.9e-43 146.6 0.0 1.8e-42 145.4 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 GAM36082.1 - 6.3e-22 77.4 0.6 1.6e-21 76.1 0.6 1.7 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 GAM36082.1 - 7e-20 72.0 0.0 4.1e-18 66.3 0.0 2.5 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain IBN_N PF03810.19 GAM36083.1 - 2e-05 24.4 0.0 7.7e-05 22.5 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep PF18773.1 GAM36083.1 - 0.00056 19.6 0.5 0.0014 18.3 0.5 1.8 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep_3 PF18806.1 GAM36083.1 - 0.00067 19.6 0.0 0.0027 17.7 0.0 2.0 1 0 0 1 1 1 1 Importin 13 repeat SOR_SNZ PF01680.17 GAM36084.1 - 1.6e-108 361.2 4.6 2.4e-108 360.6 4.6 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 GAM36084.1 - 7.6e-09 35.2 7.0 1.1e-06 28.2 0.2 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 GAM36084.1 - 0.003 17.0 0.6 0.027 13.9 0.0 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein Dus PF01207.17 GAM36084.1 - 0.0031 16.7 0.8 0.44 9.6 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.21 GAM36084.1 - 0.0031 16.7 0.0 0.18 10.9 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 GAM36084.1 - 0.0094 15.2 0.7 0.15 11.3 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 GAM36084.1 - 0.058 13.5 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 GAM36084.1 - 1.2 8.4 8.2 0.24 10.8 0.5 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase FUN14 PF04930.15 GAM36086.1 - 2.6e-10 40.6 0.8 5e-10 39.7 0.8 1.5 1 0 0 1 1 1 1 FUN14 family DsbD PF02683.15 GAM36086.1 - 0.0045 16.9 0.8 0.0067 16.3 0.5 1.4 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region ORC2 PF04084.14 GAM36087.1 - 2.3e-119 398.2 0.0 2.9e-119 397.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ORC6 PF05460.13 GAM36087.1 - 0.4 9.9 6.1 0.67 9.2 6.1 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pox_Ag35 PF03286.14 GAM36087.1 - 3.1 7.5 8.6 6.4 6.5 8.6 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ArgJ PF01960.18 GAM36088.1 - 5.9e-148 492.6 0.2 6.8e-148 492.4 0.2 1.0 1 0 0 1 1 1 1 ArgJ family SecY PF00344.20 GAM36089.1 - 1.3e-73 247.9 6.4 1.6e-73 247.6 6.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 GAM36089.1 - 2.3e-17 62.5 0.3 6e-17 61.2 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p MUG113 PF13455.6 GAM36090.1 - 2.4e-28 98.6 0.4 4.8e-28 97.6 0.4 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 GAM36090.1 - 4.1e-27 94.7 0.1 1.7e-26 92.7 0.1 2.1 1 0 0 1 1 1 1 T5orf172 domain TFIIB PF00382.19 GAM36091.1 - 0.011 15.7 0.0 0.46 10.6 0.0 2.5 2 1 0 2 2 2 0 Transcription factor TFIIB repeat Autophagy_N PF03986.13 GAM36092.1 - 8.3e-46 155.3 0.3 1.6e-45 154.4 0.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 GAM36092.1 - 1.2e-15 56.7 0.7 2.3e-15 55.8 0.7 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 GAM36092.1 - 1.2e-13 51.5 0.8 2.1e-13 50.6 0.8 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Fez1 PF06818.15 GAM36094.1 - 0.0094 16.4 0.4 0.016 15.7 0.4 1.3 1 0 0 1 1 1 1 Fez1 Striatin PF08232.12 GAM36094.1 - 0.05 14.2 0.8 0.05 14.2 0.8 2.0 2 0 0 2 2 2 0 Striatin family Cu_amine_oxid PF01179.20 GAM36095.1 - 2.2e-156 520.9 0.0 2.6e-156 520.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 GAM36095.1 - 1e-11 44.9 0.2 1.9e-11 44.0 0.2 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 GAM36095.1 - 1.6e-06 28.4 0.0 3.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain adh_short PF00106.25 GAM36096.1 - 5.6e-15 55.3 1.4 6.2e-15 55.2 1.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM36096.1 - 1.5e-10 41.1 1.1 1.7e-10 40.9 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM36096.1 - 9.2e-08 32.2 1.2 1.1e-07 32.0 1.2 1.0 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAM36096.1 - 0.00095 18.5 0.1 0.001 18.4 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 GAM36096.1 - 0.031 13.7 0.1 0.036 13.5 0.1 1.0 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Gtr1_RagA PF04670.12 GAM36096.1 - 0.078 12.3 0.1 0.17 11.2 0.0 1.5 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region Hexapep PF00132.24 GAM36097.1 - 6.7e-15 54.1 10.4 1.3e-10 40.5 6.5 3.4 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 GAM36097.1 - 4.9e-14 52.3 0.0 7.3e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 GAM36097.1 - 2.8e-13 49.4 12.8 4.8e-10 39.0 7.6 3.1 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase ACT_6 PF13740.6 GAM36097.1 - 0.034 14.1 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 ACT domain 4HBT PF03061.22 GAM36097.1 - 0.047 14.0 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily HNOBA PF07701.14 GAM36098.1 - 0.22 10.9 0.5 0.37 10.2 0.5 1.3 1 0 0 1 1 1 0 Heme NO binding associated OTT_1508_deam PF14441.6 GAM36099.1 - 8.9e-19 67.3 2.6 1.9e-18 66.2 2.6 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase adh_short PF00106.25 GAM36099.1 - 1.7e-11 44.0 0.2 1.7e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM36099.1 - 8.2e-07 28.8 0.1 0.016 14.7 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Fungal_trans_2 PF11951.8 GAM36100.1 - 4.1e-49 167.4 0.1 5.1e-49 167.1 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM36100.1 - 4.3e-07 29.9 14.5 8.5e-07 29.0 14.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 GAM36101.1 - 8.9e-55 186.2 52.4 1.1e-54 185.9 52.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM36101.1 - 5.5e-25 87.9 43.0 8.2e-25 87.3 43.0 1.1 1 0 0 1 1 1 1 Amino acid permease TEX29 PF15839.5 GAM36101.1 - 1.9 9.2 5.1 1.1 9.9 0.3 3.2 2 1 0 2 2 2 0 Testis-expressed sequence 29 protein Abhydrolase_3 PF07859.13 GAM36102.1 - 3.1e-43 148.1 0.0 3.8e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAM36102.1 - 2.9e-08 33.1 0.3 6.8e-08 31.8 0.3 1.5 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 GAM36102.1 - 0.06 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Ribonuc_L-PSP PF01042.21 GAM36103.1 - 6.2e-08 32.7 0.0 9.4e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP Amino_oxidase PF01593.24 GAM36104.1 - 1.2e-48 166.6 0.0 2.9e-48 165.3 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 GAM36104.1 - 5.7e-14 52.5 0.4 3e-13 50.1 0.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM36104.1 - 3.5e-13 49.6 0.4 2.1e-12 47.1 0.4 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GAM36104.1 - 7.5e-07 28.8 0.5 3e-06 26.8 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM36104.1 - 1.7e-06 27.4 0.6 6.1e-06 25.6 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 GAM36104.1 - 3.4e-05 23.3 0.0 0.0039 16.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 GAM36104.1 - 4.7e-05 22.7 0.1 8e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAM36104.1 - 5.5e-05 22.5 0.1 0.00026 20.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM36104.1 - 0.00012 20.9 0.2 0.00061 18.6 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 GAM36104.1 - 0.0007 18.8 0.1 0.0007 18.8 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 GAM36104.1 - 0.0011 19.5 0.1 0.0035 17.9 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM36104.1 - 0.0071 15.4 0.1 0.029 13.4 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAM36104.1 - 0.011 15.0 0.1 0.24 10.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_trans PF02705.16 GAM36105.1 - 4.1e-192 639.4 20.2 4.9e-192 639.2 20.2 1.1 1 0 0 1 1 1 1 K+ potassium transporter EST1_DNA_bind PF10373.9 GAM36106.1 - 8.5e-13 48.4 1.1 1.2e-11 44.7 0.3 2.4 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain NUDIX PF00293.28 GAM36108.1 - 8.7e-07 29.0 0.0 1.8e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 GAM36109.1 - 1.7e-19 70.2 0.0 3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain HAD_2 PF13419.6 GAM36110.1 - 1.8e-21 77.0 0.0 2.6e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM36110.1 - 1.7e-10 41.6 0.2 5.6e-10 39.9 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM36110.1 - 2.6e-06 27.4 0.1 4.9e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 GAM36110.1 - 7.2e-06 25.8 0.0 0.00059 19.6 0.0 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase HAD PF12710.7 GAM36110.1 - 0.0066 16.9 0.0 0.0091 16.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rit1_C PF17184.4 GAM36111.1 - 2.9e-99 331.9 0.0 3.7e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 GAM36111.1 - 7.3e-37 126.0 0.0 2.6e-36 124.3 0.0 1.9 2 0 0 2 2 2 1 Rit1 DUSP-like domain Aldo_ket_red PF00248.21 GAM36112.1 - 1.3e-43 149.3 0.0 1e-31 110.3 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family CH PF00307.31 GAM36113.1 - 2.2e-46 156.6 0.4 2.7e-22 79.0 0.0 2.7 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 GAM36113.1 - 2.4e-26 91.6 0.1 7.1e-26 90.1 0.1 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand RRM_1 PF00076.22 GAM36113.1 - 1.8e-15 56.5 0.0 4.5e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAMSAP_CH PF11971.8 GAM36113.1 - 3.7e-10 39.5 0.4 1.1e-06 28.4 0.1 2.6 2 0 0 2 2 2 2 CAMSAP CH domain FoP_duplication PF13865.6 GAM36113.1 - 5.8e-08 33.2 12.0 5.8e-08 33.2 12.0 3.1 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 EF-hand_6 PF13405.6 GAM36113.1 - 0.00011 21.9 0.1 0.00092 19.0 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 GAM36113.1 - 0.0005 19.4 1.1 0.011 15.3 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 GAM36113.1 - 0.00096 18.9 1.0 0.0022 17.8 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 GAM36113.1 - 0.012 16.0 3.0 0.017 15.5 0.5 2.7 2 0 0 2 2 2 0 EF-hand domain pair Spectrin PF00435.21 GAM36113.1 - 0.041 14.4 3.9 0.094 13.2 0.0 2.9 1 1 2 3 3 3 0 Spectrin repeat CH_2 PF06294.11 GAM36113.1 - 0.045 13.9 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 0 CH-like domain in sperm protein Glycos_transf_2 PF00535.26 GAM36114.1 - 2e-22 79.8 0.0 2.4e-21 76.3 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 WD40 PF00400.32 GAM36114.1 - 3.6e-11 43.4 3.9 0.076 13.9 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Glyco_tranf_2_3 PF13641.6 GAM36114.1 - 5.4e-06 26.5 0.0 0.01 15.8 0.0 3.1 3 0 0 3 3 3 2 Glycosyltransferase like family 2 ANAPC4_WD40 PF12894.7 GAM36114.1 - 0.00051 20.3 0.2 0.25 11.7 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Me-amine-dh_H PF06433.11 GAM36114.1 - 0.00078 18.4 0.0 0.26 10.1 0.0 2.2 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) Nup160 PF11715.8 GAM36114.1 - 0.017 13.8 0.2 4.3 5.9 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 STE3 PF02076.15 GAM36114.1 - 5 6.3 5.3 0.63 9.2 0.8 1.6 2 0 0 2 2 2 0 Pheromone A receptor Metallophos PF00149.28 GAM36115.1 - 3.6e-36 125.6 0.1 5.8e-36 124.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1647 PF07801.11 GAM36115.1 - 0.097 12.4 0.7 2.1 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) Abhydrolase_2 PF02230.16 GAM36117.1 - 4.1e-14 52.9 0.0 3.2e-12 46.7 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 GAM36117.1 - 0.034 13.4 0.1 1.6 7.9 0.0 2.8 2 1 0 3 3 3 0 Serine aminopeptidase, S33 DUF3759 PF12585.8 GAM36118.1 - 2.2e-41 139.8 3.7 2.6e-41 139.6 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) NmrA PF05368.13 GAM36119.1 - 1.8e-25 89.9 0.6 2.3e-23 83.0 0.6 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM36119.1 - 1.8e-20 73.6 0.6 6.3e-19 68.6 0.3 2.1 1 1 1 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAM36119.1 - 2.3e-07 31.1 0.2 4.6e-07 30.2 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 GAM36119.1 - 4.6e-05 23.9 0.1 8e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 GAM36119.1 - 0.00023 20.7 0.1 0.0015 18.1 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAM36119.1 - 0.00025 21.1 0.0 0.0011 19.0 0.1 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase CbiJ PF02571.14 GAM36119.1 - 0.0014 18.1 0.1 0.0024 17.4 0.1 1.3 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK KR PF08659.10 GAM36119.1 - 0.0027 17.7 0.1 0.005 16.8 0.1 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 GAM36119.1 - 0.011 16.3 0.3 0.023 15.2 0.3 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 GAM36119.1 - 0.03 14.4 0.1 0.067 13.3 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 GAM36119.1 - 0.035 13.6 0.2 0.057 12.9 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Ldh_1_N PF00056.23 GAM36119.1 - 0.053 13.6 0.1 0.097 12.8 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_72 PF03198.14 GAM36120.1 - 3.9e-120 400.9 11.5 5e-120 400.5 11.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 GAM36120.1 - 3.2e-21 75.8 2.5 3.2e-21 75.8 2.5 2.2 2 0 0 2 2 2 1 X8 domain Cellulase PF00150.18 GAM36120.1 - 0.00034 20.1 1.4 0.001 18.5 1.4 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NmrA PF05368.13 GAM36121.1 - 1.6e-32 113.0 0.1 2e-32 112.6 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM36121.1 - 9e-17 61.6 0.1 1.1e-16 61.2 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM36121.1 - 1.9e-08 34.1 0.0 3.9e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM36121.1 - 9.3e-05 21.6 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM36121.1 - 0.0011 18.4 0.1 0.0024 17.3 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 GAM36121.1 - 0.0017 18.3 0.1 0.0056 16.6 0.0 1.8 1 1 1 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 GAM36121.1 - 0.0076 16.5 0.1 0.016 15.4 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 GAM36121.1 - 0.011 14.9 0.1 0.57 9.3 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 GAM36121.1 - 0.036 14.7 0.1 0.43 11.2 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.12 GAM36121.1 - 0.039 13.1 0.0 0.15 11.2 0.0 2.0 1 1 0 1 1 1 0 Male sterility protein ORF_12_N PF18042.1 GAM36121.1 - 0.094 13.1 0.0 2.8 8.4 0.0 2.6 2 0 0 2 2 2 0 ORF 12 gene product N-terminal Slp PF03843.13 GAM36121.1 - 0.16 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family Meth_synt_2 PF01717.18 GAM36122.1 - 2.1e-147 490.6 0.0 1.8e-143 477.7 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 GAM36122.1 - 5.4e-117 390.8 0.0 9.6e-111 370.2 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 GAM36122.1 - 4.5e-05 22.8 0.0 0.01 15.0 0.0 2.4 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) DUF4947 PF16305.5 GAM36122.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4947) GFO_IDH_MocA PF01408.22 GAM36123.1 - 0.00023 22.0 0.0 0.00031 21.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAM36123.1 - 0.0045 17.0 0.1 0.019 15.0 0.0 1.9 1 1 1 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain ABC2_membrane PF01061.24 GAM36124.1 - 6e-78 261.1 59.9 1.1e-40 139.3 24.9 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 GAM36124.1 - 3.9e-35 121.3 0.0 7e-17 62.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 GAM36124.1 - 1.5e-26 92.1 1.1 5e-20 71.2 0.0 3.4 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 GAM36124.1 - 2.7e-14 53.5 0.2 1.7e-13 51.0 0.2 2.4 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_16 PF13191.6 GAM36124.1 - 4.8e-06 27.1 0.0 0.029 14.7 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 GAM36124.1 - 5e-06 26.5 0.8 0.081 12.7 0.0 3.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM36124.1 - 9.7e-05 22.0 0.1 0.011 15.4 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 GAM36124.1 - 0.00022 20.9 0.0 0.0066 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM36124.1 - 0.00023 21.7 0.1 0.011 16.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 GAM36124.1 - 0.00026 21.2 0.1 0.0083 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAM36124.1 - 0.00032 20.6 0.1 0.0013 18.7 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 GAM36124.1 - 0.00043 19.5 17.9 0.00043 19.5 17.9 3.6 3 1 0 3 3 3 1 ABC-2 family transporter protein AAA_17 PF13207.6 GAM36124.1 - 0.001 19.5 0.3 0.16 12.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 GAM36124.1 - 0.015 14.9 1.4 0.24 11.0 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 GAM36124.1 - 0.02 14.6 0.8 2.4 7.8 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAM36124.1 - 0.022 15.0 0.9 0.77 10.0 0.1 3.0 3 1 0 3 3 2 0 AAA domain SMC_N PF02463.19 GAM36124.1 - 0.023 14.1 1.3 0.3 10.5 0.0 3.1 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 GAM36124.1 - 0.084 13.1 1.3 0.19 12.0 0.2 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAM36124.1 - 0.084 13.0 0.2 12 6.0 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 GAM36124.1 - 0.13 12.2 1.0 7.7 6.4 0.3 2.4 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 GAM36124.1 - 0.23 11.2 0.5 8.5 6.1 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 GAM36124.1 - 0.32 10.3 1.6 12 5.1 0.0 2.9 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain AAA_23 PF13476.6 GAM36124.1 - 0.33 11.4 0.1 0.33 11.4 0.1 4.6 5 1 0 5 5 4 0 AAA domain AAA_19 PF13245.6 GAM36124.1 - 1.4 9.3 2.9 29 5.0 0.1 3.0 4 0 0 4 4 2 0 AAA domain MFS_1 PF07690.16 GAM36125.1 - 8.4e-24 84.1 22.5 1.4e-23 83.5 22.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Pannexin_like PF12534.8 GAM36125.1 - 0.17 10.9 0.0 3.8 6.5 0.0 2.1 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 TIG PF01833.24 GAM36127.1 - 3.3e-67 222.6 107.5 1.7e-12 47.2 7.3 7.0 7 0 0 7 7 7 7 IPT/TIG domain RHD_dimer PF16179.5 GAM36127.1 - 0.0076 16.3 0.0 39 4.3 0.0 4.9 5 0 0 5 5 5 1 Rel homology dimerisation domain Glyco_hydro_71 PF03659.14 GAM36128.1 - 4.9e-138 460.0 7.1 4.9e-138 460.0 7.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Peptidase_M18 PF02127.15 GAM36129.1 - 6.5e-132 440.4 0.0 7.4e-132 440.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) PHO4 PF01384.20 GAM36130.1 - 0.023 13.8 0.5 0.027 13.5 0.5 1.3 1 0 0 1 1 1 0 Phosphate transporter family BCS1_N PF08740.11 GAM36130.1 - 0.19 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 BCS1 N terminal NOB1_Zn_bind PF08772.11 GAM36131.1 - 5.7e-32 109.7 4.1 9.9e-32 108.9 4.1 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 GAM36131.1 - 1.1e-29 102.8 1.8 1.4e-29 102.4 0.1 2.2 3 0 0 3 3 3 1 PIN domain of ribonuclease zinc_ribbon_15 PF17032.5 GAM36131.1 - 0.031 15.0 0.6 0.06 14.1 0.6 1.5 1 0 0 1 1 1 0 zinc-ribbon family DZR PF12773.7 GAM36131.1 - 0.045 13.8 0.8 0.088 12.9 0.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF2321 PF10083.9 GAM36131.1 - 0.077 12.6 0.5 0.19 11.3 0.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-NADH-PPase PF09297.11 GAM36131.1 - 0.079 12.6 2.2 0.35 10.6 0.3 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain HypA PF01155.19 GAM36131.1 - 0.15 12.1 1.3 1.3 9.1 1.4 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA COMP PF11598.8 GAM36131.1 - 0.2 12.1 4.9 6.6 7.3 0.3 3.1 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein RecR PF02132.15 GAM36131.1 - 0.42 10.2 2.5 1.3 8.6 2.5 1.8 1 1 0 1 1 1 0 RecR protein Zn-ribbon_8 PF09723.10 GAM36131.1 - 1.9 8.7 5.1 0.61 10.2 1.9 1.9 2 0 0 2 2 2 0 Zinc ribbon domain Nop10p PF04135.12 GAM36132.1 - 3.9e-22 78.0 0.8 4.6e-22 77.8 0.8 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family tRNA_int_endo PF01974.17 GAM36133.1 - 1.1e-20 73.5 0.1 3.2e-20 72.0 0.1 1.8 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 GAM36133.1 - 0.0037 16.9 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Rad9_Rad53_bind PF08605.10 GAM36134.1 - 3.1e-24 85.6 0.0 5e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding Tudor_3 PF18115.1 GAM36134.1 - 1.9e-16 59.6 0.3 6.6e-16 57.9 0.2 2.0 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain BRCT_2 PF16589.5 GAM36134.1 - 1.6e-09 38.0 0.0 4.4e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAM36134.1 - 1.3e-07 31.8 0.0 4.1e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 GAM36134.1 - 8.9e-06 25.5 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Ribosomal_L27 PF01016.19 GAM36135.1 - 2e-28 98.2 0.0 2e-28 98.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal L27 protein UQ_con PF00179.26 GAM36136.1 - 1.3e-49 167.5 0.0 1.7e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TP6A_N PF04406.14 GAM36137.1 - 1.5e-21 76.1 0.0 2.9e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Receptor_IA-2 PF11548.8 GAM36137.1 - 0.034 14.1 0.2 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein-tyrosine phosphatase receptor IA-2 SQHop_cyclase_C PF13243.6 GAM36138.1 - 7.4e-50 169.9 0.1 2.2e-47 161.8 0.2 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 GAM36138.1 - 1.6e-46 158.7 1.4 1.4e-39 136.0 0.3 3.6 2 1 1 3 3 3 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 GAM36138.1 - 1.3e-31 108.0 5.3 9.3e-10 38.1 0.1 5.5 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 GAM36138.1 - 7.3e-07 28.8 0.8 0.12 11.7 0.1 4.5 3 2 2 5 5 5 2 Pectic acid lyase TED_complement PF07678.14 GAM36138.1 - 0.0005 19.2 0.2 0.15 11.1 0.1 3.4 2 1 1 4 4 4 1 A-macroglobulin TED domain TAL_FSA PF00923.19 GAM36139.1 - 2.4e-36 125.6 0.0 1.6e-33 116.3 0.0 2.1 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Peptidase_S39 PF02122.15 GAM36139.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase S39 SGS PF05002.15 GAM36140.1 - 5.9e-28 96.8 8.8 2.5e-27 94.8 8.8 2.1 1 1 0 1 1 1 1 SGS domain CS PF04969.16 GAM36140.1 - 3e-16 60.2 0.6 8e-16 58.8 0.2 2.0 2 0 0 2 2 2 1 CS domain RNA_pol_3_Rpc31 PF11705.8 GAM36140.1 - 0.0017 18.7 2.9 0.0077 16.5 2.1 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 TPR_16 PF13432.6 GAM36140.1 - 0.0042 17.7 1.4 0.22 12.2 0.1 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF4887 PF16228.5 GAM36140.1 - 0.023 14.9 8.0 0.023 14.9 8.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4887) FAM176 PF14851.6 GAM36140.1 - 0.39 10.4 2.9 0.77 9.4 2.9 1.5 1 0 0 1 1 1 0 FAM176 family Tom22 PF04281.13 GAM36140.1 - 0.61 9.9 3.6 1.4 8.7 3.6 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 GCD14 PF08704.10 GAM36141.1 - 8.6e-62 209.0 2.3 1.8e-58 198.2 2.3 2.9 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Borrelia_P83 PF05262.11 GAM36141.1 - 0.095 11.2 2.4 0.13 10.7 2.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Methyltransf_24 PF13578.6 GAM36141.1 - 0.13 13.3 0.0 0.64 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain TPR_2 PF07719.17 GAM36142.1 - 1.2e-07 31.2 0.2 0.0019 18.2 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.31 GAM36142.1 - 4.4e-06 26.5 0.0 1.3e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain TPR_1 PF00515.28 GAM36142.1 - 4.9e-05 23.0 0.2 0.069 13.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM36142.1 - 0.0042 17.3 0.1 0.13 12.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM36142.1 - 0.73 10.5 6.1 1.1 9.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1688 PF07958.11 GAM36143.1 - 9.4e-185 614.3 0.0 1.1e-184 614.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) RCDG1 PF15725.5 GAM36143.1 - 9.1 6.8 7.1 4.3 7.8 0.0 3.4 4 0 0 4 4 4 0 Renal cancer differentiation gene 1 protein Gtr1_RagA PF04670.12 GAM36144.1 - 1.2e-91 306.2 0.1 1.5e-91 305.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 GAM36144.1 - 6.3e-09 36.1 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM36144.1 - 9.1e-09 35.0 0.0 1.3e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GAM36144.1 - 4.7e-08 32.8 0.0 7.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GAM36144.1 - 3.8e-07 30.2 0.0 6.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAM36144.1 - 0.0017 17.5 2.3 0.49 9.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit AAA_29 PF13555.6 GAM36144.1 - 0.0097 15.6 0.5 0.05 13.4 0.2 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 GAM36144.1 - 0.013 14.7 0.1 0.023 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 GAM36144.1 - 0.017 15.6 0.0 0.038 14.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MMR_HSR1_Xtn PF16897.5 GAM36144.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 GAM36144.1 - 0.024 14.5 0.4 0.44 10.4 0.0 2.6 3 1 0 3 3 3 0 RsgA GTPase AIG1 PF04548.16 GAM36144.1 - 0.072 12.4 0.5 0.5 9.7 0.0 2.3 3 0 0 3 3 3 0 AIG1 family AAA_7 PF12775.7 GAM36144.1 - 0.084 12.4 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Molybdopterin PF00384.22 GAM36145.1 - 3.2e-67 227.4 0.0 5.3e-67 226.6 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 GAM36145.1 - 6.6e-27 93.7 0.0 1.7e-26 92.4 0.0 1.8 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 GAM36145.1 - 7.8e-07 29.0 0.4 2.7e-06 27.2 0.2 2.0 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain CRIC_ras_sig PF10534.9 GAM36145.1 - 0.19 11.9 0.1 0.46 10.7 0.1 1.6 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras Amidase PF01425.21 GAM36146.1 - 1.3e-35 123.2 0.3 7.7e-21 74.6 0.7 3.1 2 1 0 2 2 2 2 Amidase Methyltransf_23 PF13489.6 GAM36147.1 - 4.2e-24 85.2 0.0 7.2e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Fungal_lectin PF07938.12 GAM36147.1 - 4.9e-11 42.6 0.1 1e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 Fungal fucose-specific lectin WD40 PF00400.32 GAM36147.1 - 3.3e-10 40.4 0.2 2.3e-09 37.7 0.0 2.6 3 0 0 3 3 1 1 WD domain, G-beta repeat Methyltransf_25 PF13649.6 GAM36147.1 - 1.6e-09 38.3 0.0 4.2e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM36147.1 - 9.8e-07 29.3 0.0 2.7e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM36147.1 - 7.6e-06 26.6 0.0 3.3e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM36147.1 - 8.4e-06 25.7 0.0 7.6e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain ANAPC4_WD40 PF12894.7 GAM36147.1 - 0.00016 21.9 0.0 0.055 13.8 0.0 3.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain XhlA PF10779.9 GAM36147.1 - 0.0011 19.1 3.3 0.0024 18.1 3.3 1.5 1 0 0 1 1 1 1 Haemolysin XhlA Lebercilin PF15619.6 GAM36147.1 - 0.0045 16.7 0.5 0.0082 15.8 0.5 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Jnk-SapK_ap_N PF09744.9 GAM36147.1 - 0.0053 17.0 1.6 0.011 16.0 1.6 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Sec2p PF06428.11 GAM36147.1 - 0.0057 16.6 0.8 0.015 15.2 0.8 1.7 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p PCMT PF01135.19 GAM36147.1 - 0.011 15.5 0.0 0.16 11.7 0.0 2.1 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) YscO PF07321.12 GAM36147.1 - 0.016 15.2 0.3 0.03 14.3 0.3 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO HMMR_N PF15905.5 GAM36147.1 - 0.024 14.1 1.1 0.037 13.5 1.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 GAM36147.1 - 0.032 14.5 2.0 0.055 13.7 2.0 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) GidB PF02527.15 GAM36147.1 - 0.035 13.4 0.0 0.12 11.7 0.0 1.8 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Tropomyosin_1 PF12718.7 GAM36147.1 - 0.049 13.8 3.4 0.09 12.9 3.4 1.3 1 0 0 1 1 1 0 Tropomyosin like CENP-Q PF13094.6 GAM36147.1 - 0.066 13.4 0.3 0.12 12.5 0.3 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF16 PF01519.16 GAM36147.1 - 0.066 13.7 0.1 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 FtsJ PF01728.19 GAM36147.1 - 0.071 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Prefoldin_2 PF01920.20 GAM36147.1 - 0.083 12.8 2.3 0.16 11.9 2.3 1.4 1 0 0 1 1 1 0 Prefoldin subunit Sugarporin_N PF11471.8 GAM36147.1 - 0.13 12.3 0.6 0.26 11.3 0.6 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF4140 PF13600.6 GAM36147.1 - 0.13 12.7 2.0 0.24 11.9 1.0 1.9 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) Prefoldin PF02996.17 GAM36147.1 - 0.13 12.1 0.5 0.22 11.4 0.5 1.3 1 0 0 1 1 1 0 Prefoldin subunit TMF_DNA_bd PF12329.8 GAM36147.1 - 0.18 11.8 5.2 0.34 10.9 5.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 GAM36147.1 - 0.28 11.7 4.7 0.56 10.7 4.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_13 PF13166.6 GAM36147.1 - 0.46 9.1 1.6 0.65 8.6 1.6 1.1 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 GAM36147.1 - 0.69 8.7 3.0 1.2 8.0 3.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein GrpE PF01025.19 GAM36147.1 - 0.76 9.4 3.2 1.6 8.3 3.2 1.5 1 0 0 1 1 1 0 GrpE Polyketide_cyc2 PF10604.9 GAM36148.1 - 5.3e-08 33.2 0.0 6.1e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 GAM36148.1 - 0.063 13.5 0.0 0.073 13.3 0.0 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport K_trans PF02705.16 GAM36149.1 - 1.1e-179 598.4 19.6 1.3e-179 598.1 19.6 1.1 1 0 0 1 1 1 1 K+ potassium transporter Glyco_hydro_39 PF01229.17 GAM36150.1 - 2.2e-12 46.4 0.0 6.3e-11 41.6 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 NTP_transf_3 PF12804.7 GAM36152.1 - 3.1e-24 86.2 0.0 3.9e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain MoeA_N PF03453.17 GAM36153.1 - 8.6e-33 113.3 0.2 2.3e-32 111.9 0.1 1.7 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 GAM36153.1 - 5.5e-26 90.9 0.0 9.7e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 GAM36153.1 - 1.6e-05 25.0 0.0 4.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Adap_comp_sub PF00928.21 GAM36154.1 - 4.2e-92 308.3 0.0 9.2e-92 307.1 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAM36154.1 - 2.5e-09 37.2 0.3 4.1e-09 36.5 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 GAM36154.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.5 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Ribonucleas_3_3 PF14622.6 GAM36155.1 - 3.8e-25 88.5 0.0 8.2e-25 87.4 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 GAM36155.1 - 0.00091 19.8 0.0 0.0073 16.9 0.0 2.4 2 1 0 2 2 2 1 Ribonuclease III domain Sdh_cyt PF01127.22 GAM36156.1 - 4.8e-24 84.7 4.4 4.8e-24 84.7 4.4 1.7 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Mg_trans_NIPA PF05653.14 GAM36156.1 - 0.038 13.1 0.3 0.046 12.8 0.3 1.2 1 0 0 1 1 1 0 Magnesium transporter NIPA Hap4_Hap_bind PF10297.9 GAM36157.1 - 3.4e-09 36.5 6.9 1e-08 35.0 6.9 1.9 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 GAM36157.1 - 3.3e-07 30.3 6.8 6.3e-07 29.4 6.5 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAM36157.1 - 7.3e-05 22.8 4.0 0.00018 21.5 4.0 1.7 1 0 0 1 1 1 1 Basic region leucine zipper DUF4757 PF15949.5 GAM36157.1 - 0.0023 18.4 9.6 0.0045 17.5 8.4 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4757) Striatin PF08232.12 GAM36157.1 - 0.009 16.6 3.2 0.0092 16.6 1.5 1.8 1 1 0 1 1 1 1 Striatin family dsrm PF00035.26 GAM36157.1 - 0.018 15.7 0.0 0.054 14.2 0.0 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding motif KxDL PF10241.9 GAM36157.1 - 0.037 14.3 2.2 0.075 13.3 2.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein Phlebovirus_NSM PF07246.11 GAM36157.1 - 0.061 12.7 2.9 0.093 12.1 2.9 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M SlyX PF04102.12 GAM36157.1 - 0.11 13.2 4.2 0.35 11.5 4.2 2.0 1 0 0 1 1 1 0 SlyX Exonuc_VII_L PF02601.15 GAM36157.1 - 0.11 12.0 2.2 0.16 11.5 2.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Rab5-bind PF09311.11 GAM36157.1 - 0.2 11.0 8.8 0.37 10.1 3.3 2.1 1 1 1 2 2 2 0 Rabaptin-like protein Plk4_PB2 PF18409.1 GAM36157.1 - 0.22 12.2 2.1 0.22 12.2 0.3 1.9 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 LCD1 PF09798.9 GAM36157.1 - 0.48 8.9 3.3 0.62 8.5 3.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4775 PF16001.5 GAM36157.1 - 0.57 9.5 11.2 1.1 8.6 11.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4775) FapA PF03961.13 GAM36157.1 - 1.2 7.6 4.1 1.7 7.2 4.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prefoldin PF02996.17 GAM36157.1 - 1.3 9.0 3.9 2.9 7.8 3.3 1.8 1 1 1 2 2 2 0 Prefoldin subunit bZIP_Maf PF03131.17 GAM36157.1 - 2.2 8.8 10.9 0.41 11.2 6.8 1.8 1 1 0 2 2 2 0 bZIP Maf transcription factor DUF1542 PF07564.11 GAM36157.1 - 3.1 8.0 7.5 0.27 11.4 2.5 1.8 2 0 0 2 2 1 0 Domain of Unknown Function (DUF1542) DUF4407 PF14362.6 GAM36157.1 - 3.3 7.0 9.9 5 6.4 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 GAM36157.1 - 4.5 5.1 5.4 5.7 4.7 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Jnk-SapK_ap_N PF09744.9 GAM36157.1 - 5.4 7.2 10.0 8.5 6.6 10.0 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1640 PF07798.11 GAM36157.1 - 6 6.9 9.3 15 5.5 9.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) ADH_N PF08240.12 GAM36158.1 - 3.9e-27 94.3 1.7 6.2e-27 93.6 0.5 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 GAM36158.1 - 2.3e-07 30.6 0.2 2.3e-07 30.6 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 GAM36158.1 - 4.1e-06 26.8 0.0 0.0013 18.7 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAM36158.1 - 0.17 11.4 0.1 2.2 7.7 0.0 2.3 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus Ribosomal_L19 PF01245.20 GAM36159.1 - 5.5e-16 58.5 0.2 1e-15 57.6 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein L19 SRP9-21 PF05486.12 GAM36159.1 - 0.075 13.4 0.1 0.54 10.7 0.0 2.3 1 1 1 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) Ceramidse_alk_C PF17048.5 GAM36159.1 - 0.092 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, C-terminal AMP-binding PF00501.28 GAM36161.1 - 8.6e-08 31.2 0.0 0.00047 18.9 0.1 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Hid1 PF12722.7 GAM36162.1 - 0 1053.7 0.0 0 1053.3 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 GAM36162.1 - 4.4e-91 306.2 0.2 5.9e-91 305.8 0.2 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.11 GAM36162.1 - 7.6e-24 84.2 0.2 2.2e-23 82.8 0.0 2.0 2 0 0 2 2 2 1 Nuclear pore complex component Abhydrolase_6 PF12697.7 GAM36163.1 - 1.9e-20 74.4 0.1 2.2e-20 74.2 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM36163.1 - 0.0056 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 GAM36163.1 - 0.01 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 GAM36163.1 - 0.031 13.8 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peptidase_S9 PF00326.21 GAM36163.1 - 0.044 13.3 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_8 PF06259.12 GAM36163.1 - 0.048 13.3 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Hydrolase_4 PF12146.8 GAM36163.1 - 0.051 12.8 0.0 0.077 12.2 0.0 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 GAM36163.1 - 0.075 12.9 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase HAT_KAT11 PF08214.11 GAM36164.1 - 2.8e-100 336.0 0.0 3.8e-100 335.6 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein MAS20 PF02064.15 GAM36164.1 - 0.12 12.5 1.7 6.3 6.9 0.0 2.8 3 0 0 3 3 3 0 MAS20 protein import receptor Glyco_transf_21 PF13506.6 GAM36165.1 - 8.9e-13 48.1 0.1 6.3e-06 25.8 0.0 3.9 2 2 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 GAM36165.1 - 2.4e-07 30.9 0.0 6e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAM36165.1 - 4.1e-05 23.4 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 SRC-1 PF08832.10 GAM36165.1 - 0.35 12.0 1.6 0.79 10.8 1.6 1.6 1 0 0 1 1 1 0 Steroid receptor coactivator Ank_2 PF12796.7 GAM36166.1 - 4.1e-10 40.1 0.1 2.1e-09 37.8 0.1 2.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM36166.1 - 4.6e-09 36.4 0.5 3.3e-08 33.6 0.5 2.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 GAM36166.1 - 6.4e-08 32.7 0.6 1.3e-06 28.6 0.2 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 GAM36166.1 - 1.2e-07 31.4 0.2 2.4e-06 27.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 GAM36166.1 - 4.1e-06 27.2 0.1 1.3e-05 25.6 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) WW PF00397.26 GAM36167.1 - 4.4e-10 39.5 1.1 1e-09 38.3 1.1 1.6 1 0 0 1 1 1 1 WW domain WRW PF10206.9 GAM36167.1 - 0.025 15.0 0.8 0.12 12.8 0.8 2.0 1 1 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f FAD_binding_2 PF00890.24 GAM36168.1 - 1e-121 406.9 1.5 1.3e-121 406.6 1.5 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 GAM36168.1 - 1.8e-41 141.1 1.5 2.9e-41 140.4 1.5 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 GAM36168.1 - 7.3e-07 28.7 0.3 0.00091 18.5 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM36168.1 - 5.9e-05 22.3 0.9 0.015 14.4 1.9 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 GAM36168.1 - 0.0017 17.7 0.1 0.3 10.3 0.1 2.5 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 GAM36168.1 - 0.0028 16.9 0.3 0.0052 16.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM36168.1 - 0.018 14.6 0.4 0.031 13.9 0.4 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM36168.1 - 0.23 10.1 1.7 0.81 8.3 0.4 2.4 3 0 0 3 3 3 0 HI0933-like protein Git3 PF11710.8 GAM36169.1 - 1.3e-26 93.7 10.5 3.5e-26 92.2 10.5 1.8 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 GAM36169.1 - 2.7e-10 40.2 3.5 1e-09 38.4 0.1 2.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF2207 PF09972.9 GAM36169.1 - 0.11 11.2 0.1 0.11 11.2 0.1 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) 7tm_1 PF00001.21 GAM36169.1 - 0.24 10.7 8.7 0.37 10.1 8.7 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Hydrophobin PF01185.18 GAM36170.1 - 4.2e-09 36.9 7.5 7.2e-09 36.2 7.5 1.3 1 1 0 1 1 1 1 Fungal hydrophobin KOW PF00467.29 GAM36170.1 - 0.061 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 KOW motif NMO PF03060.15 GAM36171.1 - 1.3e-57 195.7 1.7 1.1e-56 192.6 1.7 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAM36171.1 - 1.4e-12 47.3 0.0 5.4e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAM36171.1 - 0.0018 17.4 0.1 0.0034 16.5 0.1 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 GAM36171.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.14 GAM36171.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 GAM36171.1 - 0.018 14.4 0.1 0.039 13.3 0.1 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase Glu_synthase PF01645.17 GAM36171.1 - 0.042 13.0 0.2 0.091 11.9 0.2 1.6 1 1 0 1 1 1 0 Conserved region in glutamate synthase DUF1902 PF08972.11 GAM36171.1 - 0.14 12.2 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) DUF1729 PF08354.10 GAM36171.1 - 0.18 10.6 0.1 0.4 9.5 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1729) Mito_carr PF00153.27 GAM36172.1 - 1.7e-09 37.5 6.8 0.0022 17.9 0.0 5.0 3 2 0 3 3 3 3 Mitochondrial carrier protein Fer2 PF00111.27 GAM36173.1 - 1.2e-13 50.8 0.5 1.7e-13 50.3 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain YcgR_2 PF12945.7 GAM36173.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Flagellar protein YcgR Rrp15p PF07890.12 GAM36174.1 - 6.9e-38 130.0 13.1 6.9e-38 130.0 13.1 2.5 2 1 0 2 2 2 1 Rrp15p Dioxygenase_N PF04444.14 GAM36174.1 - 0.11 12.3 0.2 4.6 7.2 0.1 2.4 2 0 0 2 2 2 0 Catechol dioxygenase N terminus Opi1 PF08618.10 GAM36174.1 - 1.3 8.2 10.7 0.32 10.2 7.2 1.7 1 1 1 2 2 2 0 Transcription factor Opi1 FAM75 PF14650.6 GAM36174.1 - 8 5.9 11.0 0.79 9.2 5.9 1.8 2 0 0 2 2 2 0 FAM75 family SRP54 PF00448.22 GAM36175.1 - 1.9e-74 249.6 2.8 1.9e-74 249.6 2.8 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 GAM36175.1 - 1.9e-28 99.0 0.2 1.9e-28 99.0 0.2 4.5 5 1 0 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.19 GAM36175.1 - 7e-21 74.2 2.2 7.8e-21 74.1 0.6 2.0 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 GAM36175.1 - 7.3e-07 28.9 0.4 2e-06 27.5 0.4 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 GAM36175.1 - 1.9e-05 25.1 2.0 1.9e-05 25.1 0.1 2.1 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 GAM36175.1 - 5.5e-05 23.4 0.1 0.00015 22.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 GAM36175.1 - 6.9e-05 23.3 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 GAM36175.1 - 0.0003 19.9 1.9 0.0022 17.0 0.2 2.9 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 GAM36175.1 - 0.0016 18.7 0.1 0.014 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 GAM36175.1 - 0.0021 18.1 0.0 0.0035 17.4 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 GAM36175.1 - 0.0022 18.1 0.2 0.02 15.0 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 GAM36175.1 - 0.0022 17.3 0.1 0.0022 17.3 0.1 1.8 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.20 GAM36175.1 - 0.0036 17.2 0.0 0.0092 15.9 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase SRPRB PF09439.10 GAM36175.1 - 0.0061 16.0 0.8 1.7 8.0 0.9 2.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 GAM36175.1 - 0.0064 17.0 0.1 0.016 15.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM36175.1 - 0.0079 15.9 0.2 0.0079 15.9 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAM36175.1 - 0.0094 16.2 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 GAM36175.1 - 0.013 15.2 0.5 0.037 13.8 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein 6PF2K PF01591.18 GAM36175.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MobB PF03205.14 GAM36175.1 - 0.017 15.0 0.1 0.054 13.4 0.0 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.17 GAM36175.1 - 0.021 14.5 0.2 0.062 13.0 0.1 1.9 2 0 0 2 2 1 0 Thymidylate kinase ResIII PF04851.15 GAM36175.1 - 0.041 13.9 1.0 0.31 11.0 1.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_31 PF13614.6 GAM36175.1 - 0.044 13.7 0.3 0.31 10.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain HAUS2 PF15003.6 GAM36175.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Methyltransf_25 PF13649.6 GAM36175.1 - 0.081 13.6 0.4 6.5 7.5 0.0 3.0 3 0 0 3 3 2 0 Methyltransferase domain AAA_24 PF13479.6 GAM36175.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Methyltransf_24 PF13578.6 GAM36175.1 - 0.15 13.1 0.0 0.37 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PHA_synth_III_E PF09712.10 GAM36175.1 - 0.21 10.7 3.6 0.43 9.6 3.6 1.5 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) T3SS_needle_F PF09392.10 GAM36175.1 - 3.8 7.8 6.0 11 6.3 1.6 3.2 3 0 0 3 3 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF PhoD PF09423.10 GAM36176.1 - 1.9e-36 125.8 0.0 4.2e-36 124.7 0.0 1.6 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 GAM36176.1 - 0.00092 19.7 0.6 0.0025 18.4 0.6 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 GAM36176.1 - 0.014 15.9 0.2 0.047 14.2 0.1 1.8 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain Glyco_hydro_18 PF00704.28 GAM36177.1 - 1.1e-12 48.3 0.0 1.9e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Zn_clus PF00172.18 GAM36177.1 - 1.8e-06 28.0 9.7 3.2e-06 27.2 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAM36177.1 - 0.00028 19.8 2.5 0.00044 19.2 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 GAM36178.1 - 1.2e-20 74.1 0.0 1.4e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAM36178.1 - 9e-06 25.8 0.3 3.2e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAM36178.1 - 5.3e-05 22.7 0.1 0.024 13.9 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 GAM36178.1 - 0.00042 20.0 1.1 0.0028 17.3 0.3 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM36178.1 - 0.0012 19.4 0.0 0.0094 16.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM36178.1 - 0.002 17.4 0.6 0.098 11.9 0.1 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM36178.1 - 0.0029 16.9 0.3 0.024 13.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM36178.1 - 0.012 14.4 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 GAM36178.1 - 0.022 13.8 0.1 0.04 13.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 GAM36178.1 - 0.039 13.2 0.5 0.078 12.2 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 GAM36178.1 - 0.055 12.5 0.2 4.9 6.1 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 GAM36178.1 - 0.17 12.1 0.1 0.52 10.6 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain KGG PF10685.9 GAM36179.1 - 4.5e-15 55.4 16.9 2e-08 34.2 0.7 3.5 3 1 1 4 4 4 3 Stress-induced bacterial acidophilic repeat motif DUF5551 PF17705.1 GAM36179.1 - 0.36 10.5 2.2 0.89 9.2 0.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5551) Fez1 PF06818.15 GAM36180.1 - 0.0014 19.1 80.8 0.1 13.1 9.5 5.5 1 1 5 6 6 6 4 Fez1 Spc7 PF08317.11 GAM36180.1 - 0.003 16.5 24.0 0.003 16.5 24.0 4.3 1 1 2 4 4 4 3 Spc7 kinetochore protein DUF4200 PF13863.6 GAM36180.1 - 0.004 17.5 19.6 0.004 17.5 19.6 6.2 3 3 2 5 5 5 1 Domain of unknown function (DUF4200) ATG16 PF08614.11 GAM36180.1 - 0.013 15.7 95.2 0.064 13.5 29.2 6.0 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) Filament PF00038.21 GAM36180.1 - 0.032 13.8 77.6 1.3 8.5 19.8 3.7 1 1 3 4 4 4 0 Intermediate filament protein HALZ PF02183.18 GAM36180.1 - 0.045 14.0 0.4 0.045 14.0 0.4 7.1 8 1 0 8 8 7 0 Homeobox associated leucine zipper BRX_N PF13713.6 GAM36180.1 - 0.074 12.8 0.1 0.074 12.8 0.1 2.6 3 0 0 3 3 3 0 Transcription factor BRX N-terminal domain SlyX PF04102.12 GAM36180.1 - 0.29 11.8 0.2 0.29 11.8 0.2 8.6 4 3 5 9 9 9 0 SlyX DUF1759 PF03564.15 GAM36180.1 - 3.7 7.5 22.2 0.35 10.8 3.3 3.9 3 3 2 5 5 5 0 Protein of unknown function (DUF1759) GAS PF13851.6 GAM36180.1 - 4 6.7 84.1 0.12 11.7 23.4 5.3 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 GAM36180.1 - 5.9 6.3 81.3 0.039 13.4 17.3 4.3 1 1 3 4 4 4 0 Hyaluronan mediated motility receptor N-terminal PalH PF08733.10 GAM36181.1 - 0.34 9.9 7.3 0.52 9.3 7.3 1.2 1 0 0 1 1 1 0 PalH/RIM21 DUF2721 PF11026.8 GAM36181.1 - 4.5 7.2 7.4 2.7 7.9 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Glyco_hydro_18 PF00704.28 GAM36182.1 - 7.7e-19 68.6 0.3 2.8e-18 66.7 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 COesterase PF00135.28 GAM36183.1 - 2.3e-81 274.2 0.0 1.9e-72 244.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM36183.1 - 2.8e-08 33.9 0.0 1.2e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM36183.1 - 0.084 12.3 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Aldo_ket_red PF00248.21 GAM36185.1 - 7.7e-41 140.2 0.0 8.7e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Spot_14 PF07084.12 GAM36186.1 - 0.13 12.4 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 adh_short PF00106.25 GAM36187.1 - 8.1e-25 87.4 0.0 3.1e-18 66.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM36187.1 - 1.8e-12 47.4 0.0 1.2e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM36187.1 - 1.2e-06 28.6 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM36187.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM36187.1 - 0.12 11.5 0.0 0.25 10.4 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Ank_2 PF12796.7 GAM36188.1 - 6.3e-45 151.7 0.0 2.7e-08 34.3 0.0 5.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM36188.1 - 9.2e-41 137.7 0.2 1.6e-07 31.7 0.0 8.5 3 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM36188.1 - 1.8e-33 114.1 2.4 2.1e-08 34.3 0.0 9.0 3 2 7 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM36188.1 - 1.4e-32 108.0 0.4 0.00076 19.7 0.0 11.2 12 0 0 12 12 12 8 Ankyrin repeat Ank PF00023.30 GAM36188.1 - 2.8e-29 100.2 0.1 4.2e-05 23.8 0.0 8.5 9 0 0 9 9 9 6 Ankyrin repeat Sugar_tr PF00083.24 GAM36189.1 - 2.5e-127 425.5 26.4 2.9e-127 425.3 26.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM36189.1 - 6.8e-23 81.2 46.7 7e-17 61.4 18.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily APH PF01636.23 GAM36190.1 - 2.3e-14 53.9 0.0 6.4e-14 52.5 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 GAM36190.1 - 0.0087 15.0 0.1 0.27 10.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 GAM36190.1 - 0.009 15.6 0.5 0.072 12.7 0.0 2.3 2 1 1 3 3 3 1 Choline/ethanolamine kinase MurB_C PF02873.16 GAM36190.1 - 0.085 12.9 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain WW PF00397.26 GAM36191.1 - 5.3e-09 36.0 1.3 1.3e-08 34.8 1.3 1.7 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 GAM36191.1 - 7.9e-05 22.8 0.3 9.2e-05 22.6 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CoA_transf_3 PF02515.17 GAM36192.1 - 1.2e-63 215.5 0.0 1.6e-63 215.1 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III DUF3364 PF11844.8 GAM36192.1 - 0.05 13.9 0.3 0.093 13.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3364) Deltaretro_Tax PF05599.11 GAM36193.1 - 0.0087 16.6 2.0 0.027 15.0 2.0 1.9 1 0 0 1 1 1 1 Deltaretrovirus Tax protein Spt20 PF12090.8 GAM36193.1 - 0.19 11.3 7.8 0.38 10.3 7.8 1.4 1 0 0 1 1 1 0 Spt20 family UCH PF00443.29 GAM36194.1 - 5.2e-23 81.9 0.0 5.7e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM36194.1 - 0.068 12.8 0.0 0.081 12.5 0.0 1.2 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase CAF1A PF12253.8 GAM36195.1 - 1.6e-21 76.2 5.4 1.6e-21 76.2 5.4 3.4 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 GAM36195.1 - 0.02 14.6 57.5 0.043 13.5 57.5 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Secretin_N_2 PF07655.13 GAM36195.1 - 0.028 15.0 0.8 0.14 12.7 0.8 2.3 1 0 0 1 1 1 0 Secretin N-terminal domain DDHD PF02862.17 GAM36195.1 - 0.55 10.4 9.3 1 9.4 5.8 3.2 2 0 0 2 2 2 0 DDHD domain Asp-B-Hydro_N PF05279.11 GAM36195.1 - 2.4 8.2 28.9 6.5 6.7 28.9 1.7 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Nucleo_P87 PF07267.11 GAM36195.1 - 3.6 6.3 23.4 10 4.8 23.4 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 GMC_oxred_N PF00732.19 GAM36196.1 - 5e-62 209.9 0.0 6.3e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM36196.1 - 1e-32 113.6 0.0 1.7e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAM36196.1 - 1.4e-07 30.9 0.1 2.5e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAM36196.1 - 5.9e-05 23.2 0.1 0.00023 21.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAM36196.1 - 0.00016 21.0 0.2 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 GAM36196.1 - 0.00094 18.4 0.5 0.035 13.2 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 GAM36196.1 - 0.001 18.7 4.5 0.0034 17.0 4.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM36196.1 - 0.0071 15.6 0.0 0.022 14.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM36196.1 - 0.028 14.4 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 GAM36196.1 - 0.06 12.0 0.3 0.099 11.3 0.1 1.4 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 GAM36196.1 - 0.11 11.6 0.1 0.2 10.7 0.0 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 GAM36196.1 - 0.25 10.2 0.4 0.35 9.7 0.4 1.1 1 0 0 1 1 1 0 Tryptophan halogenase IPP-2 PF04979.14 GAM36197.1 - 8.1e-20 71.9 24.2 5.6e-19 69.2 20.4 2.6 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) PI-PLC-C1 PF16670.5 GAM36198.1 - 1.5e-123 412.1 0.0 1.8e-123 411.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoinositide phospholipase C, Ca2+-dependent REC104 PF17378.2 GAM36198.1 - 0.13 12.1 1.6 11 5.8 0.0 2.8 2 1 0 2 2 2 0 Meiotic recombination protein REC104 Alpha_adaptinC2 PF02883.20 GAM36198.1 - 0.15 12.3 3.2 0.32 11.3 3.2 1.4 1 0 0 1 1 1 0 Adaptin C-terminal domain DUF2985 PF11204.8 GAM36199.1 - 4.9e-36 122.7 0.1 4.9e-36 122.7 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Phage_holin_3_6 PF07332.11 GAM36199.1 - 0.65 10.1 2.0 0.94 9.5 0.5 1.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III CRAL_TRIO PF00650.20 GAM36200.1 - 9.3e-16 57.9 0.0 1.3e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAM36200.1 - 3.6e-10 39.9 0.0 7.1e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain stn_TNFRSF12A PF12191.8 GAM36200.1 - 0.23 11.7 0.3 38 4.5 0.8 2.5 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SAM_decarbox PF01536.16 GAM36201.1 - 1.3e-133 445.4 0.0 1.5e-133 445.2 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TAF6_C PF07571.13 GAM36202.1 - 9.8e-31 105.9 0.0 2.4e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 GAM36202.1 - 1e-25 89.7 0.1 1.9e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 GAM36202.1 - 0.0024 18.2 0.2 0.0058 17.0 0.1 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAM36202.1 - 0.004 17.4 0.1 0.012 15.9 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAM36202.1 - 0.0093 16.0 0.1 0.028 14.5 0.1 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAM36202.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated TAFII28 PF04719.14 GAM36203.1 - 1.4e-25 89.2 1.1 8.4e-24 83.5 0.3 2.3 2 0 0 2 2 2 2 hTAFII28-like protein conserved region Endonuc_Holl PF10107.9 GAM36203.1 - 0.24 11.2 2.7 0.55 10.1 2.7 1.6 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase SRP-alpha_N PF04086.13 GAM36203.1 - 3.2 7.6 8.2 0.24 11.3 2.0 1.9 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal APH PF01636.23 GAM36207.1 - 0.0082 16.1 0.2 0.023 14.6 0.2 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fungal_trans PF04082.18 GAM36208.1 - 7.7e-15 54.6 0.3 1.3e-14 53.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM36208.1 - 3.9e-07 30.1 11.1 7.3e-07 29.2 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 60KD_IMP PF02096.20 GAM36209.1 - 1.1e-19 71.0 0.3 2e-19 70.1 0.3 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein Herpes_BLLF1 PF05109.13 GAM36209.1 - 0.09 10.7 0.1 0.15 10.0 0.1 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) AAA_8 PF12780.7 GAM36209.1 - 0.27 10.5 1.5 1.5 8.1 0.4 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 SRP-alpha_N PF04086.13 GAM36209.1 - 2.2 8.1 17.1 3 7.7 17.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TOM13 PF08219.11 GAM36210.1 - 6.8e-33 112.5 0.0 9.5e-33 112.0 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.13 GAM36211.1 - 9.7e-25 87.0 0.0 2.1e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.6 GAM36211.1 - 9.5e-16 57.3 0.4 1.7e-15 56.6 0.4 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 GAM36211.1 - 6e-14 52.0 0.0 1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.13 GAM36211.1 - 0.0001 21.8 0.1 0.00017 21.2 0.1 1.3 1 0 0 1 1 1 1 TAP C-terminal domain DUF3572 PF12096.8 GAM36211.1 - 0.13 12.4 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3572) ParA PF10609.9 GAM36212.1 - 1.1e-84 283.8 0.0 2.6e-84 282.5 0.0 1.5 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAM36212.1 - 2.6e-09 37.2 0.0 9.9e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 GAM36212.1 - 4.6e-06 26.1 0.0 7.5e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.6 GAM36212.1 - 0.00016 21.6 0.5 0.0003 20.7 0.5 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 GAM36212.1 - 0.00055 19.6 0.1 0.00087 18.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 GAM36212.1 - 0.00068 18.9 0.2 0.001 18.3 0.2 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 GAM36212.1 - 0.0054 16.2 0.0 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 GAM36212.1 - 0.01 14.8 0.5 0.015 14.3 0.5 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_26 PF13500.6 GAM36212.1 - 0.03 14.1 1.4 4.5 7.1 0.7 2.7 2 1 2 4 4 4 0 AAA domain APS_kinase PF01583.20 GAM36212.1 - 0.061 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Fer4_NifH PF00142.18 GAM36212.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family COG2 PF06148.11 GAM36214.1 - 6.1e-35 120.2 0.3 1.1e-34 119.4 0.3 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 GAM36214.1 - 4.6e-05 23.4 1.2 0.00061 19.8 0.0 2.6 2 1 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.9 GAM36214.1 - 0.02 15.0 0.9 0.058 13.6 0.1 2.2 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 GAM36214.1 - 0.029 14.3 0.2 0.054 13.4 0.2 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Nop25 PF09805.9 GAM36214.1 - 0.094 13.2 1.1 0.16 12.4 1.1 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Bcr-Abl_Oligo PF09036.10 GAM36214.1 - 0.1 12.6 0.6 0.56 10.3 0.0 2.5 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain SKA2 PF16740.5 GAM36214.1 - 0.15 11.9 1.8 0.84 9.5 0.2 2.6 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 THOC7 PF05615.13 GAM36214.1 - 0.44 10.8 4.4 1.8 8.8 1.9 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 Ribosomal_L1 PF00687.21 GAM36215.1 - 2.6e-28 99.2 0.0 3.3e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.21 GAM36216.1 - 1.1e-92 310.3 0.0 1.6e-92 309.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAM36216.1 - 7e-36 123.7 0.3 1.4e-35 122.8 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 GAM36216.1 - 0.018 15.2 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tetraspanin PF00335.20 GAM36217.1 - 5.7e-06 26.2 0.6 9.6e-06 25.5 0.1 1.6 2 0 0 2 2 2 1 Tetraspanin family Arylesterase PF01731.20 GAM36218.1 - 0.00044 20.4 0.0 0.0012 19.0 0.0 1.8 2 0 0 2 2 2 1 Arylesterase SGL PF08450.12 GAM36218.1 - 0.0084 15.7 0.0 0.014 15.0 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 GAM36218.1 - 0.083 13.0 0.0 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Strictosidine synthase Lactonase PF10282.9 GAM36218.1 - 0.12 11.6 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller TUDOR PF00567.24 GAM36218.1 - 0.12 12.4 0.1 4.4 7.4 0.4 2.6 2 1 1 3 3 3 0 Tudor domain E1-E2_ATPase PF00122.20 GAM36219.1 - 1.9e-36 125.3 3.7 1.7e-22 79.8 0.1 3.6 3 0 0 3 3 3 3 E1-E2 ATPase Hydrolase PF00702.26 GAM36219.1 - 2.9e-17 63.7 0.2 3.6e-16 60.1 0.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM36219.1 - 2.5e-10 39.9 0.0 5.2e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM36219.1 - 0.0068 16.2 0.2 0.023 14.5 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CDC45 PF02724.14 GAM36219.1 - 0.083 11.2 1.8 0.12 10.7 1.8 1.2 1 0 0 1 1 1 0 CDC45-like protein FixP_N PF14715.6 GAM36219.1 - 1.5 8.6 5.9 11 5.8 0.5 2.8 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Glyco_hydro_18 PF00704.28 GAM36220.1 - 3e-22 79.7 6.2 2.3e-21 76.8 6.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 MPM1 PF17234.2 GAM36221.1 - 0.0028 17.9 1.2 0.0078 16.5 1.2 1.8 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 Sugar_tr PF00083.24 GAM36222.1 - 8.8e-31 107.2 19.0 3.1e-16 59.3 6.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM36222.1 - 7.2e-11 41.6 33.6 3.8e-07 29.4 9.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Borrelia_P13 PF05628.12 GAM36222.1 - 0.98 9.4 6.9 0.59 10.1 1.2 3.0 4 0 0 4 4 4 0 Borrelia membrane protein P13 Fungal_trans PF04082.18 GAM36223.1 - 0.00014 21.0 0.2 0.00039 19.5 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Phosphodiest PF01663.22 GAM36224.1 - 6e-32 111.6 0.0 1.1e-31 110.7 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HD PF01966.22 GAM36224.1 - 4.9e-06 26.8 0.2 1.2e-05 25.5 0.2 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 GAM36224.1 - 0.007 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 HDOD domain MIOX PF05153.15 GAM36224.1 - 0.029 13.9 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol oxygenase HD_4 PF13328.6 GAM36224.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 HD domain PhyH PF05721.13 GAM36225.1 - 4e-27 95.8 0.0 5.8e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) KR PF08659.10 GAM36225.1 - 3.8e-06 27.0 0.1 6.1e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 KR domain 2OG-FeII_Oxy_5 PF13759.6 GAM36225.1 - 0.00034 21.0 0.0 0.00063 20.1 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 GAM36225.1 - 0.079 13.9 0.0 0.17 12.8 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.7 GAM36226.1 - 5.3e-17 63.2 1.4 6.1e-17 63.0 1.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM36226.1 - 0.0075 15.9 0.0 0.1 12.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM36226.1 - 0.0077 15.5 0.1 0.26 10.5 0.1 2.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Questin_oxidase PF14027.6 GAM36227.1 - 7.2e-90 302.0 0.1 9.5e-90 301.6 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like Aldo_ket_red PF00248.21 GAM36228.1 - 1.9e-37 129.1 0.0 2.6e-36 125.4 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family PSK_trans_fac PF07704.11 GAM36228.1 - 0.16 12.7 0.0 1.2 10.0 0.0 2.2 2 0 0 2 2 2 0 Rv0623-like transcription factor ERCC3_RAD25_C PF16203.5 GAM36229.1 - 6.2e-70 235.2 0.2 6.2e-70 235.2 0.2 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C PF00271.31 GAM36229.1 - 3.3e-05 24.2 0.0 9.3e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_3 PF13625.6 GAM36230.1 - 3.1e-35 121.1 0.0 1.1e-34 119.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GAM36230.1 - 4.2e-22 78.6 0.2 9e-22 77.5 0.2 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 GAM36230.1 - 6.1e-16 58.9 0.0 9.8e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 GAM36230.1 - 1.5e-08 33.8 0.0 1.5e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 GAM36230.1 - 0.00044 20.1 0.0 0.00071 19.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 GAM36230.1 - 0.00095 18.1 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF4677 PF15726.5 GAM36230.1 - 0.037 14.2 0.8 0.066 13.4 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) AChE_tetra PF08674.10 GAM36230.1 - 4.4 7.1 5.5 1.2 8.9 0.9 2.3 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain DUF4748 PF15932.5 GAM36231.1 - 3.7e-12 45.8 1.8 3.7e-12 45.8 1.8 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4748) CTD_bind PF04818.13 GAM36232.1 - 9.8e-10 39.1 0.0 2.8e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Sugar_tr PF00083.24 GAM36233.1 - 3.8e-101 339.2 14.7 4.4e-101 339.0 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM36233.1 - 4.1e-23 81.9 17.7 4.1e-23 81.9 17.7 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Epimerase PF01370.21 GAM36234.1 - 1.3e-13 51.0 0.0 3.6e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM36234.1 - 4.1e-13 49.0 0.0 6.9e-13 48.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAM36234.1 - 5.7e-11 42.1 0.0 3.3e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 GAM36234.1 - 2.3e-10 40.7 0.0 3.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM36234.1 - 7e-08 32.3 0.2 2.9e-07 30.3 0.2 1.9 2 1 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 GAM36234.1 - 6.6e-07 29.0 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 GAM36234.1 - 3.5e-05 23.4 0.3 6e-05 22.6 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM36234.1 - 0.00021 21.2 0.1 0.0007 19.5 0.1 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM36234.1 - 0.0022 17.2 0.1 0.0052 16.0 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAM36234.1 - 0.041 13.0 0.0 0.094 11.8 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain MR_MLE_C PF13378.6 GAM36235.1 - 1.6e-50 171.7 0.2 2.4e-50 171.1 0.2 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 GAM36235.1 - 3.5e-07 30.4 0.0 6.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 GAM36235.1 - 0.055 12.6 0.0 0.11 11.7 0.0 1.4 1 1 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Fungal_trans PF04082.18 GAM36236.1 - 5.3e-05 22.4 0.3 0.00012 21.2 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tyrosinase PF00264.20 GAM36236.1 - 0.15 12.3 0.6 7.9 6.7 0.3 2.2 2 0 0 2 2 2 0 Common central domain of tyrosinase Glyco_hydro_3_C PF01915.22 GAM36237.1 - 9.5e-56 189.0 0.0 2.1e-55 187.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAM36237.1 - 3.2e-45 154.9 0.0 5.2e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM36237.1 - 1.4e-21 76.4 0.6 7.8e-21 74.0 0.1 2.4 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 GAM36237.1 - 1.8e-18 66.8 0.0 4.2e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 PA14 domain DUF11 PF01345.18 GAM36237.1 - 0.018 15.3 0.3 0.11 12.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF11 Phage_tail_X PF05489.12 GAM36237.1 - 0.026 14.2 0.1 0.063 13.0 0.1 1.6 1 0 0 1 1 1 0 Phage Tail Protein X NPCBM_assoc PF10633.9 GAM36237.1 - 0.082 13.2 1.6 0.34 11.2 1.6 2.1 1 1 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase CARDB PF07705.11 GAM36237.1 - 0.099 12.9 0.8 0.38 11.0 0.3 2.2 2 1 0 2 2 2 0 CARDB Fungal_trans PF04082.18 GAM36238.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain MFS_1 PF07690.16 GAM36239.1 - 8.1e-17 61.2 19.7 8.1e-17 61.2 19.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_tail_X PF05489.12 GAM36239.1 - 0.11 12.1 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 Phage Tail Protein X EMP24_GP25L PF01105.24 GAM36240.1 - 2.5e-46 157.9 3.3 3.1e-46 157.6 3.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Spc7 PF08317.11 GAM36240.1 - 0.08 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MFS_1 PF07690.16 GAM36241.1 - 1.5e-27 96.5 56.4 1.5e-27 96.5 56.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM36241.1 - 1.1e-10 41.0 6.6 1.1e-10 41.0 6.6 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter DUF5027 PF16430.5 GAM36241.1 - 0.19 11.5 0.2 0.47 10.2 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5027) FAD_binding_3 PF01494.19 GAM36242.1 - 2.8e-08 33.4 0.0 3.4e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM36242.1 - 1.2e-07 31.7 4.5 0.0044 16.6 0.1 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM36242.1 - 1.6e-06 27.5 1.1 2.3e-06 27.0 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GAM36242.1 - 2.7e-06 27.8 0.2 0.0007 20.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM36242.1 - 3.8e-06 26.4 0.2 3.3e-05 23.3 0.1 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM36242.1 - 1.9e-05 24.8 1.2 0.00013 22.1 1.0 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAM36242.1 - 0.00011 21.0 0.1 0.00015 20.6 0.1 1.3 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAM36242.1 - 0.00084 18.7 0.4 0.0015 17.8 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAM36242.1 - 0.0029 17.0 0.1 0.0029 17.0 0.1 1.3 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAM36242.1 - 0.0039 16.3 0.1 0.0039 16.3 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAM36242.1 - 0.051 12.9 1.7 0.059 12.7 1.2 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase BCDHK_Adom3 PF10436.9 GAM36243.1 - 1.3e-47 161.6 0.1 2.7e-47 160.6 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAM36243.1 - 3.4e-05 24.3 0.0 0.0002 21.9 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAM36243.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPC22 PF04573.12 GAM36244.1 - 1.3e-39 135.4 0.0 8.1e-27 93.8 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit HDA2-3 PF11496.8 GAM36245.1 - 9.4e-36 123.5 4.0 7.1e-35 120.6 0.0 3.1 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Pmp3 PF01679.17 GAM36245.1 - 1.1e-19 70.3 9.5 2.1e-19 69.4 9.5 1.5 1 0 0 1 1 1 1 Proteolipid membrane potential modulator HAD PF12710.7 GAM36245.1 - 1e-18 68.4 0.0 2.2e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.6 GAM36245.1 - 3.3e-10 40.5 0.2 3.3e-10 40.5 0.2 3.4 2 1 0 2 2 2 1 AAA domain UPRTase PF14681.6 GAM36245.1 - 3.3e-09 36.5 0.2 8.6e-08 31.9 0.3 2.5 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase Hydrolase PF00702.26 GAM36245.1 - 1.3e-06 28.9 0.1 4.6e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_18 PF13238.6 GAM36245.1 - 0.0051 17.4 0.0 0.023 15.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain HAD_2 PF13419.6 GAM36245.1 - 0.007 16.5 0.7 0.029 14.4 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase AAA PF00004.29 GAM36245.1 - 0.016 15.6 0.1 0.078 13.4 0.0 2.3 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Pribosyltran PF00156.27 GAM36245.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl transferase domain AAA_16 PF13191.6 GAM36245.1 - 0.023 15.1 0.0 0.023 15.1 0.0 2.4 2 1 0 2 2 1 0 AAA ATPase domain KAP_NTPase PF07693.14 GAM36245.1 - 0.029 13.6 1.6 0.15 11.3 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_24 PF13479.6 GAM36245.1 - 0.053 13.3 0.1 0.17 11.6 0.1 1.9 1 0 0 1 1 1 0 AAA domain Hydrolase_3 PF08282.12 GAM36245.1 - 0.076 12.7 3.3 0.11 12.2 0.0 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Rootletin PF15035.6 GAM36245.1 - 0.19 11.7 22.3 0.45 10.5 22.3 1.7 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion AAA_22 PF13401.6 GAM36245.1 - 0.24 11.7 2.2 0.7 10.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAM36245.1 - 0.41 10.5 1.8 0.43 10.5 0.1 1.9 2 0 0 2 2 2 0 NACHT domain GAS PF13851.6 GAM36245.1 - 0.77 9.1 31.9 0.61 9.4 9.4 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 GAM36245.1 - 2.8 8.1 26.2 0.41 10.8 3.2 3.4 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase IF4E PF01652.18 GAM36247.1 - 2.4e-53 180.2 0.0 4e-53 179.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.19 GAM36247.1 - 2e-34 119.3 0.0 5e-34 118.0 0.0 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain REPA_OB_2 PF16900.5 GAM36247.1 - 0.14 12.1 0.0 0.52 10.3 0.0 2.0 1 0 0 1 1 1 0 Replication protein A OB domain GGACT PF06094.12 GAM36248.1 - 7.3e-15 55.6 0.0 1.2e-14 54.9 0.0 1.3 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like GTP_cyclohydroI PF01227.22 GAM36249.1 - 1.4e-66 223.3 0.1 2.4e-66 222.6 0.1 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 GAM36249.1 - 0.0098 16.0 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein CAF1C_H4-bd PF12265.8 GAM36250.1 - 2.5e-28 98.1 1.1 9.9e-28 96.2 1.0 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 GAM36250.1 - 8.7e-26 89.7 7.8 2.8e-05 24.8 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM36250.1 - 3.5e-07 30.4 1.4 0.023 15.0 0.1 4.6 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 GAM36250.1 - 0.0011 17.4 0.1 0.36 9.1 0.0 2.1 1 1 1 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz SGL PF08450.12 GAM36250.1 - 0.015 14.9 0.1 0.04 13.5 0.0 1.6 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region DUF3751 PF12571.8 GAM36250.1 - 0.018 15.1 0.1 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Phage tail-collar fibre protein XRN_M PF17846.1 GAM36251.1 - 6.4e-100 335.2 3.3 1e-99 334.5 3.3 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 GAM36251.1 - 5.5e-96 320.7 1.4 7.5e-96 320.2 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 GAM36251.1 - 3.3e-76 255.3 0.6 7.6e-76 254.2 0.0 1.8 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 GAM36251.1 - 3.8e-31 107.1 0.0 1.3e-30 105.4 0.0 2.0 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 GAM36251.1 - 7.4e-24 83.6 0.3 1.8e-23 82.4 0.3 1.7 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 GAM36251.1 - 1.8e-07 31.1 1.3 5.1e-07 29.7 1.3 1.8 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 P68HR PF08061.11 GAM36252.1 - 0.067 13.3 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 P68HR (NUC004) repeat Pkinase PF00069.25 GAM36253.1 - 5.9e-62 209.4 0.0 8.5e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM36253.1 - 4e-30 105.0 0.0 1.7e-29 102.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM36253.1 - 0.00036 20.0 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM36253.1 - 0.0063 15.9 0.2 0.012 15.0 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM36253.1 - 0.016 14.0 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF2961 PF11175.8 GAM36254.1 - 0.017 14.8 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) adh_short PF00106.25 GAM36255.1 - 5.6e-32 110.8 0.0 3.6e-31 108.2 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM36255.1 - 1.8e-28 99.7 0.1 1.6e-26 93.3 0.1 2.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM36255.1 - 5.6e-10 39.4 0.0 1.3e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAM36255.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 GAM36255.1 - 0.032 13.4 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glu_dehyd_C PF16912.5 GAM36255.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NUDIX PF00293.28 GAM36256.1 - 2.1e-18 66.6 0.1 4.3e-18 65.6 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 GAM36256.1 - 3.3e-12 46.9 0.0 7.1e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 GAM36256.1 - 8.6e-07 28.5 1.3 1.4e-06 27.8 1.3 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain GDE_N PF12439.8 GAM36256.1 - 0.053 12.9 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal DUF4139 PF13598.6 GAM36257.1 - 1.6e-33 116.2 0.0 1.6e-33 116.2 0.0 3.2 2 2 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 GAM36257.1 - 2.5e-24 85.6 0.2 2.5e-24 85.6 0.2 4.2 3 1 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) TFIIA PF03153.13 GAM36257.1 - 0.0024 17.9 7.5 0.0024 17.9 7.5 3.1 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit E_Pc_C PF06752.12 GAM36257.1 - 0.018 15.2 7.6 0.056 13.6 7.6 1.9 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Gemini_BL1 PF00845.19 GAM36257.1 - 0.023 14.3 2.6 1.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Geminivirus BL1 movement protein CIA30 PF08547.12 GAM36257.1 - 0.063 13.3 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) AAA_23 PF13476.6 GAM36257.1 - 0.2 12.1 6.9 15 6.0 6.3 2.7 2 0 0 2 2 2 0 AAA domain Pex14_N PF04695.13 GAM36257.1 - 4.2 8.0 13.4 0.4 11.3 6.1 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hydin_ADK PF17213.3 GAM36257.1 - 6.6 7.0 7.0 3 8.1 0.5 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF3987 PF13148.6 GAM36257.1 - 8.3 5.3 11.4 0.53 9.2 5.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Fungal_trans PF04082.18 GAM36258.1 - 1.1e-05 24.6 0.0 2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM36258.1 - 0.00013 22.0 9.2 0.00024 21.2 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NCD3G PF07562.14 GAM36258.1 - 0.13 12.2 3.3 0.25 11.3 3.3 1.4 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR MFS_1 PF07690.16 GAM36259.1 - 2.1e-39 135.5 52.6 8e-39 133.5 49.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM36259.1 - 8.6e-15 54.2 23.9 1.2e-14 53.7 23.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 GAM36259.1 - 1.2 9.4 5.9 0.17 12.1 0.9 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 NMT1_3 PF16868.5 GAM36260.1 - 0.027 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family NMT1_2 PF13379.6 GAM36260.1 - 0.08 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family PQ-loop PF04193.14 GAM36261.1 - 3.6e-18 65.1 6.9 2e-11 43.5 0.0 2.6 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 GAM36261.1 - 6.9e-05 23.7 1.8 0.00012 22.9 1.8 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor Glyco_hydro_31 PF01055.26 GAM36262.1 - 2.4e-137 458.7 12.5 3.4e-137 458.2 12.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GAM36262.1 - 1.5e-26 92.5 0.7 4.3e-26 91.0 0.2 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 GAM36262.1 - 1.8e-06 28.1 0.4 5.6e-06 26.5 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NDK PF00334.19 GAM36263.1 - 9.4e-54 181.1 0.0 1.1e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MTHFR PF02219.17 GAM36264.1 - 2.8e-102 341.9 0.0 3.4e-101 338.3 0.0 2.0 2 0 0 2 2 2 2 Methylenetetrahydrofolate reductase TGT PF01702.18 GAM36265.1 - 5.3e-63 213.3 0.0 6.9e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylate_kin PF02223.17 GAM36266.1 - 3.6e-48 163.7 0.0 4.2e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 GAM36266.1 - 0.2 11.1 0.0 0.78 9.1 0.0 1.9 2 1 0 2 2 2 0 Chromatin associated protein KTI12 GIY-YIG PF01541.24 GAM36267.1 - 1.1e-14 54.4 0.0 3.6e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 GIY-YIG catalytic domain FANCL_C PF11793.8 GAM36267.1 - 3.1e-05 24.1 3.4 5.5e-05 23.3 3.4 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 GAM36267.1 - 0.00031 20.9 0.9 0.00069 19.8 0.9 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 GAM36267.1 - 0.0022 17.9 3.5 0.0022 17.9 3.5 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 GAM36267.1 - 0.0024 18.2 5.9 0.0045 17.3 5.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H_2 PF13832.6 GAM36267.1 - 0.011 15.9 2.3 0.011 15.9 2.3 1.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain PHD PF00628.29 GAM36267.1 - 0.047 13.6 5.5 0.11 12.4 5.5 1.7 1 0 0 1 1 1 0 PHD-finger FYDLN_acid PF09538.10 GAM36267.1 - 0.077 13.7 2.8 0.16 12.7 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-RING-like PF08746.11 GAM36267.1 - 0.36 11.2 6.8 1 9.7 6.8 1.9 1 1 0 1 1 1 0 RING-like domain NinG PF05766.12 GAM36267.1 - 0.36 10.7 6.5 1.4 8.8 1.5 2.2 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein C1_1 PF00130.22 GAM36267.1 - 0.7 9.8 5.9 0.12 12.3 1.9 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PLU-1 PF08429.11 GAM36268.1 - 8.2e-109 363.9 21.9 2.6e-104 349.0 20.3 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 GAM36268.1 - 6.6e-44 149.0 0.4 2e-43 147.4 0.3 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 GAM36268.1 - 2.8e-22 79.2 0.1 9.7e-22 77.5 0.1 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 GAM36268.1 - 2.4e-17 62.6 1.9 6.4e-17 61.2 1.9 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 GAM36268.1 - 2.8e-13 50.0 6.5 5.7e-13 49.0 6.5 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.29 GAM36268.1 - 2.9e-07 30.3 15.5 6.1e-07 29.2 7.9 2.6 2 0 0 2 2 2 2 PHD-finger Tma16 PF11176.8 GAM36268.1 - 0.23 11.3 5.4 0.45 10.4 0.6 2.6 2 0 0 2 2 2 0 Translation machinery-associated protein 16 DHHA2 PF02833.14 GAM36269.1 - 3.5e-33 114.8 0.0 5.7e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 GAM36269.1 - 3.1e-05 24.1 0.0 6.5e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 DHH family Transglut_core PF01841.19 GAM36270.1 - 1.8e-08 34.8 0.0 5.4e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily ketoacyl-synt PF00109.26 GAM36271.1 - 1e-80 271.0 0.0 1.7e-80 270.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 GAM36271.1 - 5.2e-42 144.2 1.4 3.3e-31 108.9 0.0 3.5 2 1 1 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 GAM36271.1 - 3.3e-41 141.8 0.0 5.4e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM36271.1 - 6.8e-36 122.9 0.5 1.8e-35 121.5 0.5 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 GAM36271.1 - 4.8e-23 81.3 4.8 4.7e-11 42.9 0.7 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 GAM36271.1 - 6.8e-23 82.0 0.0 3.4e-22 79.7 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 GAM36271.1 - 9.6e-14 51.3 0.0 1.5e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 GAM36271.1 - 5.6e-05 22.6 0.0 0.00021 20.7 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 GAM36271.1 - 0.00014 22.5 0.1 0.0057 17.3 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 GAM36271.1 - 0.0038 17.7 0.0 0.009 16.5 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension DUF2974 PF11187.8 GAM36271.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cu-oxidase_3 PF07732.15 GAM36272.1 - 1.4e-39 134.7 2.4 3.6e-39 133.5 2.4 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAM36272.1 - 2.3e-28 98.6 5.0 6.1e-22 77.8 0.0 4.0 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 GAM36272.1 - 2.2e-14 53.9 0.0 1.9e-13 50.8 0.0 2.3 2 1 0 2 2 2 1 Multicopper oxidase SGL PF08450.12 GAM36273.1 - 0.00037 20.2 0.4 0.00056 19.6 0.4 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 GAM36273.1 - 0.035 13.4 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) AIM24 PF01987.17 GAM36273.1 - 0.071 12.9 0.0 0.2 11.4 0.0 1.8 1 1 0 1 1 1 0 Mitochondrial biogenesis AIM24 Scytalone_dh PF02982.14 GAM36274.1 - 2.3e-85 284.3 3.0 2.7e-85 284.1 3.0 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 GAM36274.1 - 3.5e-08 33.6 1.8 4.4e-08 33.3 1.8 1.1 1 0 0 1 1 1 1 SnoaL-like domain adh_short_C2 PF13561.6 GAM36275.1 - 9.2e-58 195.6 0.3 1.7e-57 194.7 0.3 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM36275.1 - 8.7e-48 162.4 0.8 1.1e-47 162.1 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM36275.1 - 8.8e-19 68.1 0.3 1.2e-18 67.7 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM36275.1 - 0.00046 19.7 0.1 0.0006 19.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 GAM36275.1 - 0.21 11.6 1.6 3.9 7.5 0.8 2.4 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF1100 PF06500.11 GAM36276.1 - 3.9e-09 35.8 0.0 5.8e-09 35.2 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 GAM36276.1 - 7e-07 28.9 0.0 4.9e-06 26.2 0.0 2.4 1 1 1 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 GAM36276.1 - 0.0006 19.8 0.0 0.0012 18.8 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 GAM36276.1 - 0.0011 18.3 0.0 0.0082 15.4 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 GAM36276.1 - 0.0039 16.9 0.1 0.014 15.1 0.1 1.8 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 GAM36276.1 - 0.0062 17.2 0.9 0.0096 16.5 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 GAM36276.1 - 0.058 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 GAM36276.1 - 0.082 12.5 0.0 0.98 9.0 0.0 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 GAM36276.1 - 0.11 12.0 0.0 0.8 9.2 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Cu-oxidase PF00394.22 GAM36277.1 - 5.5e-39 133.8 2.4 7.3e-38 130.2 0.2 2.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAM36277.1 - 1.1e-36 125.6 2.9 2.8e-36 124.3 2.9 1.7 1 0 0 1 1 1 1 Multicopper oxidase Fungal_trans PF04082.18 GAM36278.1 - 7.1e-07 28.5 0.0 1.3e-05 24.4 0.0 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM36278.1 - 0.0018 18.4 2.9 0.0038 17.3 2.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.10 GAM36278.1 - 0.18 12.2 1.2 0.59 10.5 1.2 1.9 1 0 0 1 1 1 0 HalX domain Cyclase PF04199.13 GAM36279.1 - 2e-11 44.3 0.0 4.1e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 Putative cyclase WD40 PF00400.32 GAM36280.1 - 1.8e-38 129.8 15.8 8.7e-08 32.7 0.0 11.4 12 0 0 12 12 12 6 WD domain, G-beta repeat Utp12 PF04003.12 GAM36280.1 - 1e-27 96.5 0.0 1.7e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 GAM36280.1 - 2.1e-19 69.6 0.0 0.59 10.5 0.0 10.0 4 2 6 11 11 11 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM36280.1 - 4.6e-10 39.0 1.2 0.067 12.1 0.0 5.5 3 2 3 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Utp21 PF04192.12 GAM36280.1 - 0.00093 18.8 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain Gmad1 PF10647.9 GAM36280.1 - 0.0014 18.4 4.1 0.046 13.5 0.0 3.5 2 1 2 4 4 4 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 GAM36280.1 - 0.0028 16.4 6.7 3.3 6.2 0.0 5.2 3 3 3 6 6 6 2 Nucleoporin Nup120/160 eIF2A PF08662.11 GAM36280.1 - 0.004 17.1 6.4 0.31 10.9 1.0 5.4 5 3 3 8 8 8 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 GAM36280.1 - 0.0076 14.8 0.0 0.093 11.2 0.0 2.5 3 1 0 3 3 3 1 Cytochrome D1 heme domain WD40_like PF17005.5 GAM36280.1 - 0.018 14.4 0.0 2.4 7.4 0.0 3.4 4 0 0 4 4 4 0 WD40-like domain PQQ_3 PF13570.6 GAM36280.1 - 0.039 14.4 8.8 3.6 8.2 0.0 6.2 7 0 0 7 7 7 0 PQQ-like domain Inositol_P PF00459.25 GAM36280.1 - 0.1 12.1 0.0 0.34 10.4 0.0 1.8 1 0 0 1 1 1 0 Inositol monophosphatase family Septin PF00735.18 GAM36281.1 - 1.1e-114 382.5 0.2 1.8e-114 381.8 0.2 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAM36281.1 - 1.6e-07 31.4 0.0 3.6e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM36281.1 - 5.5e-06 26.4 1.2 5.5e-05 23.1 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 GAM36281.1 - 9.7e-05 22.0 8.0 9.8e-05 22.0 0.5 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 GAM36281.1 - 0.00072 19.8 0.6 0.0021 18.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 GAM36281.1 - 0.0026 17.3 0.1 0.0051 16.3 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 GAM36281.1 - 0.0037 17.5 0.2 0.0084 16.3 0.2 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 GAM36281.1 - 0.0057 16.0 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 GAM36281.1 - 0.0082 15.2 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FOXP-CC PF16159.5 GAM36281.1 - 0.013 16.1 2.2 0.024 15.3 0.9 2.2 1 1 1 2 2 1 0 FOXP coiled-coil domain AAA_24 PF13479.6 GAM36281.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAM36281.1 - 0.028 14.8 0.6 0.084 13.2 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.14 GAM36281.1 - 0.035 13.4 0.1 0.05 12.8 0.1 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Ras PF00071.22 GAM36281.1 - 0.036 13.6 1.1 0.13 11.8 0.5 2.2 2 1 0 2 2 2 0 Ras family T2SSE PF00437.20 GAM36281.1 - 0.041 12.9 0.6 0.079 12.0 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 GAM36281.1 - 0.056 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 GAM36281.1 - 0.064 12.8 0.3 0.59 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GAM36281.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 GAM36281.1 - 0.089 12.5 0.4 4.1 7.1 0.4 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 GAM36281.1 - 0.091 13.3 1.4 0.18 12.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.18 GAM36281.1 - 0.091 12.1 0.4 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 GAM36281.1 - 0.12 12.7 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Casc1_N PF15927.5 GAM36281.1 - 0.13 12.0 10.9 0.3 10.7 10.9 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus ATP_bind_1 PF03029.17 GAM36281.1 - 0.2 11.4 0.9 12 5.6 0.1 2.8 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 GAM36281.1 - 0.76 9.8 7.4 3.6 7.6 0.1 3.1 2 1 1 3 3 3 0 Dynamin family AAA_11 PF13086.6 GAM36281.1 - 4.8 6.9 7.6 25 4.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain DegS PF05384.11 GAM36281.1 - 7.5 6.0 16.0 2.7 7.5 9.5 2.8 2 1 1 3 3 3 0 Sensor protein DegS APG6_N PF17675.1 GAM36281.1 - 8.4 6.9 15.3 2 8.9 10.6 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region ABC_tran PF00005.27 GAM36282.1 - 2.6e-46 157.5 0.1 5.7e-24 85.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAM36282.1 - 7.3e-39 134.1 27.7 1.3e-29 103.7 16.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region WD40 PF00400.32 GAM36282.1 - 2.7e-16 59.6 14.4 0.0025 18.6 0.3 6.3 6 0 0 6 6 5 5 WD domain, G-beta repeat SMC_N PF02463.19 GAM36282.1 - 1.8e-09 37.4 5.3 4.1e-05 23.1 0.1 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAM36282.1 - 1.6e-08 34.8 4.8 0.0099 15.7 0.1 4.2 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM36282.1 - 6.8e-07 28.9 0.8 0.0029 17.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ANAPC4_WD40 PF12894.7 GAM36282.1 - 7.8e-07 29.3 0.3 0.72 10.2 0.0 4.9 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_23 PF13476.6 GAM36282.1 - 8.7e-06 26.4 2.0 0.025 15.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 GAM36282.1 - 2.1e-05 24.6 0.2 0.38 10.8 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_22 PF13401.6 GAM36282.1 - 0.0002 21.7 0.1 0.28 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 GAM36282.1 - 0.0003 20.9 0.4 0.44 10.6 0.0 2.6 2 0 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 GAM36282.1 - 0.00084 19.3 1.8 0.61 10.0 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 GAM36282.1 - 0.0021 18.5 0.2 0.21 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 GAM36282.1 - 0.0049 16.1 0.9 17 4.5 0.2 3.3 3 0 0 3 3 3 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 GAM36282.1 - 0.0054 16.1 0.5 2 7.7 0.2 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family NACHT PF05729.12 GAM36282.1 - 0.013 15.4 0.7 1.6 8.7 0.0 2.9 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 GAM36282.1 - 0.02 14.5 1.7 1.1 8.8 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PQQ PF01011.21 GAM36282.1 - 0.02 14.8 0.1 0.99 9.5 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat DUF87 PF01935.17 GAM36282.1 - 0.028 14.5 3.9 0.73 9.9 0.6 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain DUF5046 PF16465.5 GAM36282.1 - 0.073 12.5 0.1 0.31 10.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) GTP_EFTU PF00009.27 GAM36282.1 - 0.093 12.3 0.2 8 6.0 0.1 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.12 GAM36282.1 - 0.098 11.9 0.1 3.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 GAM36282.1 - 0.11 11.5 0.7 4.8 6.2 0.2 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein UL41A PF17591.2 GAM36282.1 - 0.12 12.4 0.9 2.7 8.2 0.1 2.9 2 0 0 2 2 2 0 Herpesvirus UL41A AAA_30 PF13604.6 GAM36282.1 - 0.15 11.7 0.1 11 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 GAM36282.1 - 0.17 11.5 0.7 20 4.8 0.3 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain LCCL PF03815.19 GAM36284.1 - 1.2e-22 79.9 0.4 1.9e-22 79.2 0.4 1.2 1 0 0 1 1 1 1 LCCL domain GLEYA PF10528.9 GAM36285.1 - 1.3e-15 57.5 0.9 1.3e-15 57.5 0.9 2.6 3 1 0 3 3 3 1 GLEYA domain Trp_syntA PF00290.20 GAM36286.1 - 6.3e-92 307.1 0.4 1.9e-58 197.3 0.0 2.7 2 1 1 3 3 3 2 Tryptophan synthase alpha chain PALP PF00291.25 GAM36286.1 - 2.4e-39 135.5 0.6 4.7e-39 134.6 0.6 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.16 GAM36287.1 - 4.5e-23 81.7 53.3 7.4e-17 61.3 22.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM36287.1 - 0.00043 19.0 12.6 0.00043 19.0 12.6 2.8 1 1 2 3 3 3 2 MFS/sugar transport protein Aminotran_1_2 PF00155.21 GAM36288.1 - 3.1e-09 36.5 0.0 5.6e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Antimicrobial_1 PF08018.11 GAM36289.1 - 0.15 12.3 0.4 0.3 11.3 0.4 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide Sdh5 PF03937.16 GAM36290.1 - 1.2e-24 86.1 0.5 3.2e-24 84.7 0.5 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase WD40 PF00400.32 GAM36291.1 - 3e-46 154.4 20.4 8.8e-10 39.0 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM36291.1 - 2.7e-10 40.4 0.3 0.058 13.7 0.0 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM36291.1 - 3e-06 26.2 6.7 0.059 12.0 0.1 4.7 2 1 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAM36291.1 - 0.0011 18.0 0.0 12 4.7 0.0 4.1 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAM36291.1 - 0.0017 18.3 0.0 0.76 9.6 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 GAM36291.1 - 0.003 16.2 0.0 0.61 8.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 GAM36291.1 - 0.0064 15.9 0.0 0.83 8.9 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain PD40 PF07676.12 GAM36291.1 - 0.017 15.1 0.4 22 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat TPR_10 PF13374.6 GAM36292.1 - 0.0064 16.3 0.2 3 7.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM36292.1 - 0.024 14.6 3.3 16 5.8 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM36292.1 - 0.12 12.7 4.6 2.6 8.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM36292.1 - 0.13 12.8 6.7 0.36 11.4 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAM36292.1 - 0.27 11.9 1.6 2.9 8.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM36292.1 - 0.39 11.0 8.3 41 4.6 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM36292.1 - 1.3 10.0 6.1 46 5.2 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SRAP PF02586.14 GAM36293.1 - 2.8e-81 272.3 0.2 4e-81 271.7 0.2 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) ACT_7 PF13840.6 GAM36294.1 - 7.5e-27 92.9 0.1 9.4e-19 67.0 0.0 3.4 3 0 0 3 3 3 3 ACT domain SKIP_SNW PF02731.15 GAM36296.1 - 2.2e-71 238.7 7.1 2.2e-71 238.7 7.1 3.5 4 0 0 4 4 4 1 SKIP/SNW domain DUF3395 PF11875.8 GAM36296.1 - 1.8e-42 144.9 0.4 1.8e-42 144.9 0.4 4.7 4 1 0 4 4 4 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 GAM36296.1 - 2.7e-16 59.5 0.4 6.7e-16 58.2 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L4 PF00573.22 GAM36297.1 - 2.7e-35 121.8 0.7 7.6e-35 120.3 0.7 1.7 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 GAM36297.1 - 1.5e-30 105.0 1.6 4e-30 103.7 1.6 1.7 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain DUF1485 PF07364.12 GAM36299.1 - 1.2e-106 356.2 0.2 1.9e-106 355.6 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M81 MlrC_C PF07171.12 GAM36299.1 - 4.5e-59 199.6 0.2 8.9e-59 198.6 0.2 1.5 1 0 0 1 1 1 1 MlrC C-terminus UPF0029 PF01205.19 GAM36299.1 - 1.8e-34 118.2 0.0 1.4e-33 115.4 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 GAM36299.1 - 8.2e-08 32.5 0.0 1.4e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 RWD domain Sugar_tr PF00083.24 GAM36300.1 - 1.8e-72 244.7 19.2 2.1e-72 244.4 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM36300.1 - 1.2e-23 83.6 32.5 1.2e-23 83.6 32.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM36301.1 - 1.2e-71 241.9 12.8 1.4e-71 241.7 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM36301.1 - 3.1e-18 65.8 16.2 3.1e-18 65.8 16.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Pox_EPC_I2-L1 PF12575.8 GAM36302.1 - 0.011 16.0 0.1 0.019 15.2 0.1 1.4 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 MFS_1 PF07690.16 GAM36303.1 - 7.4e-32 110.6 26.7 1.1e-31 110.0 26.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM36303.1 - 0.00018 20.9 6.2 0.00018 20.9 6.2 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB EMP24_GP25L PF01105.24 GAM36304.1 - 4.3e-39 134.3 0.0 4.9e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 GAM36304.1 - 0.043 12.0 0.8 0.056 11.6 0.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA NDUFA12 PF05071.16 GAM36308.1 - 2.7e-12 47.3 7.9 9e-12 45.7 7.9 2.0 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.31 GAM36309.1 - 1e-14 54.6 0.0 2e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF4677 PF15726.5 GAM36309.1 - 0.076 13.2 1.7 0.12 12.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4677) CAMSAP_CH PF11971.8 GAM36309.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain Zein PF01559.16 GAM36310.1 - 0.0097 15.5 0.9 0.016 14.8 0.9 1.3 1 0 0 1 1 1 1 Zein seed storage protein MFS_1 PF07690.16 GAM36312.1 - 2.2e-19 69.6 22.7 2.9e-09 36.3 0.0 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM36312.1 - 0.00092 18.2 13.6 0.083 11.7 0.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter ORMDL PF04061.14 GAM36313.1 - 3.9e-58 195.1 5.0 4.7e-58 194.8 5.0 1.1 1 0 0 1 1 1 1 ORMDL family SAGA-Tad1 PF12767.7 GAM36314.1 - 0.0057 16.4 3.9 0.0081 15.9 3.9 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit zf-CCHC_3 PF13917.6 GAM36314.1 - 0.021 14.8 0.1 0.043 13.8 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Hydrolase PF00702.26 GAM36315.1 - 2.5e-15 57.3 0.0 3.1e-12 47.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAM36315.1 - 1.6e-14 54.4 0.0 5.8e-14 52.6 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM36315.1 - 9.3e-07 28.8 0.0 2.6e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 GAM36315.1 - 0.0012 19.3 0.0 0.005 17.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 GAM36315.1 - 0.0092 15.6 0.1 0.3 10.7 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Hydrolase_6 PF13344.6 GAM36315.1 - 0.048 13.8 0.0 2.9 8.0 0.0 2.8 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TRP PF06011.12 GAM36318.1 - 2.1e-164 547.3 27.3 2.7e-164 547.0 27.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 GAM36318.1 - 1.8e-43 148.2 1.6 2.9e-43 147.6 1.6 1.3 1 0 0 1 1 1 1 ML-like domain Ac76 PF05814.11 GAM36318.1 - 0.21 11.6 6.9 2.5 8.2 0.7 3.1 2 1 1 3 3 3 0 Orf76 (Ac76) SLATT_fungal PF18142.1 GAM36318.1 - 0.89 9.6 4.8 2.8 8.0 2.3 2.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain zf-U1 PF06220.12 GAM36319.1 - 1.4e-06 28.0 1.0 1.8e-06 27.6 1.0 1.2 1 0 0 1 1 1 1 U1 zinc finger Glyco_hydro_88 PF07470.13 GAM36320.1 - 1.4e-42 146.0 1.1 2e-42 145.5 1.1 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF3602 PF12223.8 GAM36320.1 - 1.3e-24 86.5 0.2 6.2e-22 78.0 0.2 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) COesterase PF00135.28 GAM36321.1 - 2.5e-52 178.4 0.0 3.5e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM36321.1 - 0.0018 18.2 0.1 0.77 9.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold tRNA-synt_1c PF00749.21 GAM36322.1 - 4.1e-92 308.4 0.0 5.8e-92 307.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Sugar_tr PF00083.24 GAM36322.1 - 5.2e-83 279.4 21.2 6.7e-83 279.0 21.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter tRNA-synt_1c_C PF03950.18 GAM36322.1 - 1.1e-34 119.8 0.0 2.2e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain MFS_1 PF07690.16 GAM36322.1 - 4.4e-18 65.3 35.0 8.2e-18 64.4 28.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_C_3 PF14497.6 GAM36322.1 - 0.011 16.0 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TRI12 PF06609.13 GAM36322.1 - 0.061 11.7 9.6 0.72 8.2 0.3 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_32N PF00251.20 GAM36323.1 - 8.9e-70 235.7 7.8 1.1e-69 235.3 7.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 GAM36323.1 - 6.2e-20 71.8 0.2 1.3e-19 70.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Hydrolase_4 PF12146.8 GAM36324.1 - 4.2e-10 39.3 0.5 5.5e-10 38.9 0.5 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM36324.1 - 8.5e-10 39.6 6.5 1.3e-09 39.0 5.9 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAM36324.1 - 1.5e-09 37.7 0.0 4.5e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GAM36324.1 - 6.8e-09 35.7 0.0 9.1e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 GAM36324.1 - 3.2e-07 30.2 0.3 4.7e-07 29.7 0.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 GAM36324.1 - 0.00023 21.1 0.0 0.00042 20.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAM36324.1 - 0.014 15.2 0.3 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S28 PF05577.12 GAM36324.1 - 0.044 12.6 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 COesterase PF00135.28 GAM36324.1 - 0.25 10.2 0.0 0.25 10.2 0.0 1.4 2 0 0 2 2 2 0 Carboxylesterase family adh_short PF00106.25 GAM36325.1 - 1.6e-37 128.9 0.0 3.3e-37 127.8 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM36325.1 - 7e-25 87.9 0.0 1.1e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAM36325.1 - 1.7e-07 31.0 0.0 3.9e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAM36325.1 - 1.1e-06 28.7 0.8 4.9e-05 23.3 0.8 2.2 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 GAM36325.1 - 0.034 13.3 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF3216 PF11505.8 GAM36325.1 - 0.043 14.0 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) CENP-F_leu_zip PF10473.9 GAM36326.1 - 0.025 14.6 12.0 0.065 13.3 12.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sigma70_r2 PF04542.14 GAM36326.1 - 0.044 13.5 0.0 0.19 11.5 0.0 2.1 1 0 0 1 1 1 0 Sigma-70 region 2 HALZ PF02183.18 GAM36326.1 - 0.98 9.7 6.7 0.63 10.3 4.1 2.1 1 1 1 2 2 2 0 Homeobox associated leucine zipper GAS PF13851.6 GAM36326.1 - 1.1 8.6 19.3 4.7 6.5 16.4 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Dioxygenase_C PF00775.21 GAM36327.1 - 2e-42 144.7 0.0 2.6e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 GAM36327.1 - 3e-24 84.7 0.0 4.7e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus SpaA PF17802.1 GAM36327.1 - 0.022 15.1 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 Prealbumin-like fold domain CarboxypepD_reg PF13620.6 GAM36327.1 - 0.026 14.8 0.0 0.074 13.3 0.0 1.7 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain CSS-motif PF12792.7 GAM36327.1 - 0.18 11.3 0.1 0.26 10.7 0.1 1.2 1 0 0 1 1 1 0 CSS motif domain associated with EAL DUF846 PF05832.12 GAM36328.1 - 1.4e-49 167.7 9.8 1.7e-49 167.5 9.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4133 PF13571.6 GAM36328.1 - 3.5 8.0 6.1 1.2 9.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) HpcH_HpaI PF03328.14 GAM36329.1 - 9.5e-46 155.7 0.2 3.7e-45 153.8 0.0 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 GAM36329.1 - 1.8e-15 57.0 0.3 4.4e-07 29.4 0.0 2.0 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold SnoaL_3 PF13474.6 GAM36329.1 - 0.011 16.0 0.0 3.8 7.8 0.0 2.3 2 0 0 2 2 2 0 SnoaL-like domain PK PF00224.21 GAM36329.1 - 0.022 13.6 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain DUF1771 PF08590.10 GAM36330.1 - 2.2e-14 53.5 10.3 5.1e-14 52.4 10.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 GAM36330.1 - 2.3e-08 33.8 9.6 1.7e-05 24.7 1.8 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 GAM36330.1 - 3.4e-08 33.2 2.1 0.0024 17.7 0.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.21 GAM36330.1 - 1.1e-06 28.9 0.1 4.7e-06 26.9 0.1 2.1 2 0 0 2 2 2 1 Smr domain zf-CCCH_2 PF14608.6 GAM36330.1 - 4.6e-05 23.7 6.4 0.021 15.3 0.9 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 GAM36330.1 - 0.00033 20.4 12.4 0.0019 17.9 1.7 3.1 2 1 0 2 2 2 2 CCCH-type zinc finger SapB_1 PF05184.15 GAM36330.1 - 0.00063 19.7 2.8 0.46 10.5 0.0 2.8 3 0 0 3 3 3 2 Saposin-like type B, region 1 zf-CCCH_3 PF15663.5 GAM36330.1 - 0.00091 19.4 2.4 0.52 10.5 0.1 2.4 1 1 1 2 2 2 2 Zinc-finger containing family CUE PF02845.16 GAM36330.1 - 0.0095 15.6 0.1 0.029 14.1 0.1 1.9 1 0 0 1 1 1 1 CUE domain Torus PF16131.5 GAM36330.1 - 0.27 11.9 3.5 3.1 8.6 0.5 2.7 1 1 1 2 2 2 0 Torus domain SNARE_assoc PF09335.11 GAM36331.1 - 8.1e-12 45.7 5.8 8.1e-12 45.7 5.8 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF4199 PF13858.6 GAM36331.1 - 1.1 9.6 10.7 1.7 9.0 6.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) MPP6 PF10175.9 GAM36332.1 - 9.7e-06 26.1 10.3 0.0001 22.8 10.3 2.1 1 1 0 1 1 1 1 M-phase phosphoprotein 6 zf-CHCC PF10276.9 GAM36333.1 - 3.1e-17 62.3 0.6 5e-17 61.7 0.6 1.3 1 0 0 1 1 1 1 Zinc-finger domain UPF0047 PF01894.17 GAM36334.1 - 2.3e-37 127.6 0.0 2.7e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Ank_2 PF12796.7 GAM36335.1 - 5.6e-54 180.7 0.5 3e-16 59.8 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM36335.1 - 2e-45 152.6 1.8 3.6e-11 43.4 0.0 7.1 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM36335.1 - 1.4e-44 144.9 0.1 4e-06 26.7 0.0 8.8 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 GAM36335.1 - 1.9e-42 141.9 0.0 3.2e-08 33.7 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 GAM36335.1 - 5.5e-36 122.2 2.9 2.7e-07 30.7 0.1 6.7 2 2 5 7 7 7 6 Ankyrin repeats (many copies) TetR_C_24 PF17932.1 GAM36336.1 - 0.06 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PH PF00169.29 GAM36337.1 - 1.9e-05 25.1 0.7 4.5e-05 23.9 0.7 1.6 1 0 0 1 1 1 1 PH domain FAD-oxidase_C PF02913.19 GAM36338.1 - 1e-53 182.6 0.0 1.8e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain RmlD_sub_bind PF04321.17 GAM36338.1 - 1.7e-43 148.8 0.1 2.9e-43 148.0 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain FAD_binding_4 PF01565.23 GAM36338.1 - 2.1e-37 127.9 0.5 4.8e-37 126.8 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain Epimerase PF01370.21 GAM36338.1 - 1.8e-10 40.7 0.0 3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM36338.1 - 0.0026 16.8 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAM36338.1 - 0.0067 15.6 0.0 0.071 12.2 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Pkinase PF00069.25 GAM36339.1 - 1.3e-69 234.5 0.0 1.8e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM36339.1 - 4.6e-46 157.2 0.0 6.7e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM36339.1 - 3.2e-06 26.2 0.0 7.7e-06 24.9 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAM36339.1 - 0.0008 18.8 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Glycos_transf_2 PF00535.26 GAM36339.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF4048 PF13257.6 GAM36340.1 - 1.9e-89 299.9 30.8 1.9e-89 299.9 30.8 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4048) GrpE PF01025.19 GAM36340.1 - 0.0024 17.5 0.6 0.0024 17.5 0.6 1.6 2 0 0 2 2 2 1 GrpE Bap31_Bap29_C PF18035.1 GAM36340.1 - 0.079 13.0 4.2 0.05 13.6 1.9 1.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Tim17 PF02466.19 GAM36341.1 - 4.1e-35 120.5 6.0 5.7e-35 120.0 6.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Oxidored_molyb PF00174.19 GAM36342.1 - 2.2e-61 206.4 0.2 3.1e-61 206.0 0.2 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 GAM36342.1 - 1.9e-23 83.0 0.1 3.9e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Big_7 PF17957.1 GAM36342.1 - 0.022 15.5 0.2 0.2 12.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig domain PALP PF00291.25 GAM36343.1 - 2e-67 227.7 0.2 2.3e-67 227.5 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cnd3 PF12719.7 GAM36344.1 - 1.1e-92 310.3 1.1 1.5e-91 306.6 0.2 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 GAM36344.1 - 2.6e-05 24.5 12.0 0.0093 16.3 2.4 4.7 2 2 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 GAM36344.1 - 9.9e-05 22.8 2.7 0.15 12.6 0.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat UNC45-central PF11701.8 GAM36344.1 - 0.0028 17.6 1.4 0.86 9.5 0.0 3.5 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central HEAT PF02985.22 GAM36344.1 - 0.0087 16.2 11.1 3.4 8.2 0.0 6.6 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.7 GAM36344.1 - 0.012 15.7 2.9 0.14 12.2 0.1 3.8 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 GAM36344.1 - 0.12 12.5 0.3 4.2 7.6 0.0 3.1 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3558 PF12079.8 GAM36344.1 - 0.14 12.1 2.4 0.34 10.9 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) zf-RanBP PF00641.18 GAM36345.1 - 4e-11 42.0 1.6 7.2e-11 41.2 1.6 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 GAM36345.1 - 6.3e-08 32.3 0.0 1.4e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 GAM36345.1 - 6.3e-07 30.1 0.0 9.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Proteasome PF00227.26 GAM36346.1 - 1.4e-55 187.7 0.1 1.9e-55 187.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAM36346.1 - 6e-13 48.2 0.3 2.1e-12 46.5 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 GAM36346.1 - 0.16 11.9 0.1 0.35 10.8 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) WD40 PF00400.32 GAM36347.1 - 3.1e-18 65.8 22.7 0.00011 22.9 0.1 8.7 7 1 1 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM36347.1 - 2.9e-09 37.1 6.1 0.92 9.8 0.2 5.9 4 2 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM36347.1 - 0.00085 18.4 0.7 2.6 6.9 0.1 3.3 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAM36347.1 - 0.0022 17.9 1.3 0.31 10.9 0.5 3.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CLTH PF10607.9 GAM36347.1 - 0.022 14.6 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Nup160 PF11715.8 GAM36347.1 - 0.026 13.2 4.0 0.041 12.5 0.1 3.0 4 0 0 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 GAM36347.1 - 0.082 12.2 0.2 14 4.9 0.0 3.2 3 0 0 3 3 3 0 WD40-like domain PQQ_2 PF13360.6 GAM36347.1 - 0.12 12.0 4.6 2.2 7.8 0.8 3.6 2 2 0 2 2 2 0 PQQ-like domain Kelch_3 PF13415.6 GAM36347.1 - 0.24 11.7 2.6 13 6.2 0.0 4.7 4 0 0 4 4 4 0 Galactose oxidase, central domain PQQ_3 PF13570.6 GAM36347.1 - 3.1 8.4 9.3 3.7 8.2 0.8 4.2 4 0 0 4 4 4 0 PQQ-like domain Na_Ala_symp PF01235.17 GAM36348.1 - 0.046 13.0 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Sodium:alanine symporter family ATP-synt_ab PF00006.25 GAM36349.1 - 3.3e-110 366.8 0.0 4.7e-110 366.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 GAM36349.1 - 5.7e-47 158.5 0.0 1.1e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 GAM36349.1 - 5e-15 55.8 1.0 9.8e-15 54.8 1.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Dynamin_M PF01031.20 GAM36350.1 - 2e-102 342.3 0.1 3.7e-102 341.4 0.1 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 GAM36350.1 - 2.5e-57 193.6 0.1 5.1e-57 192.6 0.1 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 GAM36350.1 - 2e-30 104.8 6.6 2e-30 104.8 6.6 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GAM36350.1 - 3.6e-05 23.8 0.5 0.00022 21.3 0.5 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2226 PF09987.9 GAM36350.1 - 0.0012 18.2 0.4 0.18 11.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2226) FeoB_N PF02421.18 GAM36350.1 - 0.064 12.8 0.6 16 5.0 0.1 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B Y_phosphatase2 PF03162.13 GAM36350.1 - 0.092 12.3 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family AAA_15 PF13175.6 GAM36350.1 - 0.99 9.0 5.6 6.1 6.5 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain CN_hydrolase PF00795.22 GAM36351.1 - 3.4e-35 121.6 0.0 4.7e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Reticulon PF02453.17 GAM36352.1 - 0.84 9.6 6.7 5.7 6.9 1.4 2.3 2 0 0 2 2 2 0 Reticulon Glyco_hydro_16 PF00722.21 GAM36353.1 - 1.1e-08 34.8 0.3 1.8e-08 34.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Arf PF00025.21 GAM36356.1 - 3e-07 30.1 0.0 1e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 GAM36356.1 - 0.11 11.7 0.0 0.26 10.4 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit bMG6 PF17962.1 GAM36356.1 - 0.18 12.0 0.6 0.38 10.9 0.3 1.7 2 0 0 2 2 2 0 Bacterial macroglobulin domain 6 BTRD1 PF17660.1 GAM36357.1 - 9e-11 41.4 2.8 0.0049 16.6 0.2 3.2 3 0 0 3 3 3 3 Bacterial tandem repeat domain 1 Serpin PF00079.20 GAM36358.1 - 7.3e-63 213.1 0.3 8.4e-63 212.9 0.3 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) NDC10_II PF16787.5 GAM36358.1 - 0.0047 16.0 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Egh16-like PF11327.8 GAM36359.1 - 6.1e-43 147.4 3.5 7.1e-43 147.1 3.5 1.0 1 0 0 1 1 1 1 Egh16-like virulence factor HemeBinding_Shp PF11545.8 GAM36359.1 - 0.0032 17.5 0.1 0.0073 16.3 0.1 1.7 1 1 1 2 2 2 1 Cell surface heme-binding protein Shp Gpr1_Fun34_YaaH PF01184.19 GAM36360.1 - 7.6e-70 234.7 19.8 9.2e-70 234.4 19.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family FAA_hydrolase PF01557.18 GAM36361.1 - 1.6e-64 217.5 0.0 3.1e-64 216.6 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_1 PF00561.20 GAM36361.1 - 4.4e-22 79.0 0.3 2e-19 70.2 0.1 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM36361.1 - 5.6e-17 63.1 0.0 8.8e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM36361.1 - 2.8e-16 59.5 0.0 5.8e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAM36361.1 - 4.1e-07 30.4 0.1 5.5e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 GAM36361.1 - 0.00027 20.8 0.0 0.00066 19.6 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase Ndr PF03096.14 GAM36361.1 - 0.0021 16.8 0.0 0.0031 16.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.13 GAM36361.1 - 0.012 15.4 0.1 0.51 10.0 0.0 2.3 1 1 0 2 2 2 0 PGAP1-like protein Chlorophyllase2 PF12740.7 GAM36361.1 - 0.088 11.7 0.2 0.19 10.6 0.2 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 GAM36361.1 - 0.16 10.5 0.0 0.27 9.7 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II TrkH PF02386.16 GAM36362.1 - 1e-151 505.8 14.8 1.4e-151 505.4 3.8 2.3 2 1 0 2 2 2 2 Cation transport protein NPP1 PF05630.11 GAM36363.1 - 0.00016 21.9 3.7 0.0073 16.4 3.7 2.2 1 1 0 1 1 1 1 Necrosis inducing protein (NPP1) GFA PF04828.14 GAM36364.1 - 2.2e-05 24.7 5.3 0.006 16.9 0.0 2.8 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.6 GAM36364.1 - 0.044 13.2 0.5 0.044 13.2 0.5 2.4 3 0 0 3 3 3 0 zinc-ribbon domain Abhydrolase_2 PF02230.16 GAM36365.1 - 2.8e-26 92.7 0.0 9.4e-17 61.5 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 GAM36365.1 - 0.00012 21.7 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 GAM36365.1 - 0.004 17.0 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold ADH_zinc_N PF00107.26 GAM36366.1 - 7.9e-23 80.9 0.0 1.3e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM36366.1 - 4.9e-22 77.9 1.1 8.1e-22 77.2 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM36366.1 - 3.9e-11 44.1 0.0 6.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YAcAr PF10686.9 GAM36366.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family adh_short PF00106.25 GAM36366.1 - 0.16 11.4 0.2 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase DUF726 PF05277.12 GAM36366.1 - 0.32 9.9 0.6 0.49 9.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) MFS_1 PF07690.16 GAM36367.1 - 5e-31 107.9 32.1 5e-31 107.9 32.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_5 PF05631.14 GAM36367.1 - 4.7e-07 29.1 3.9 4.7e-07 29.1 3.9 1.5 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Glug PF07581.12 GAM36367.1 - 0.029 14.8 0.2 0.12 12.8 0.2 2.1 1 0 0 1 1 1 0 The GLUG motif CPP1-like PF11833.8 GAM36367.1 - 0.74 9.4 8.1 0.75 9.4 3.1 2.6 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like FAD_binding_3 PF01494.19 GAM36368.1 - 2.6e-18 66.4 1.4 2.1e-16 60.1 1.4 2.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM36368.1 - 1.3e-08 34.9 2.3 9.4e-07 28.7 1.9 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM36368.1 - 1.4e-08 34.4 1.4 2.9e-06 26.7 0.5 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM36368.1 - 3e-07 30.5 0.9 6.9e-07 29.4 0.9 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM36368.1 - 4.3e-07 29.4 3.2 6.9e-07 28.7 3.2 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 GAM36368.1 - 5.4e-07 28.8 1.9 0.0014 17.5 0.4 2.7 2 1 1 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.12 GAM36368.1 - 6.1e-06 25.5 0.3 1.5e-05 24.2 0.3 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 GAM36368.1 - 4.2e-05 22.4 0.9 0.0001 21.1 1.1 1.5 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 GAM36368.1 - 9.9e-05 21.6 0.1 0.00014 21.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAM36368.1 - 0.00013 21.3 0.9 0.00051 19.4 1.4 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM36368.1 - 0.00013 21.3 0.3 0.00025 20.3 0.3 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 GAM36368.1 - 0.00016 21.2 1.1 0.00022 20.7 1.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAM36368.1 - 0.00033 20.0 0.1 0.00059 19.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 GAM36368.1 - 0.0044 16.4 0.2 0.041 13.2 0.1 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 GAM36368.1 - 0.0049 17.4 0.3 0.03 14.9 1.0 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 GAM36368.1 - 0.061 12.9 0.3 0.11 12.1 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 GAM36368.1 - 0.073 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 GAM36368.1 - 0.093 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_9 PF13454.6 GAM36368.1 - 0.11 12.4 0.7 1 9.3 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 GAM36368.1 - 0.16 11.9 0.9 0.26 11.2 0.9 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Melibiase_2 PF16499.5 GAM36369.1 - 1.3e-55 188.6 7.2 7e-36 123.9 0.7 2.6 3 0 0 3 3 3 2 Alpha galactosidase A MFS_1 PF07690.16 GAM36369.1 - 1.6e-30 106.2 27.8 2.1e-30 105.8 27.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Melibiase_C PF17801.1 GAM36369.1 - 3.7e-12 46.2 4.6 1e-11 44.8 0.2 3.4 4 0 0 4 4 4 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 GAM36369.1 - 9.2e-06 24.8 0.0 2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Melibiase DUF5392 PF17370.2 GAM36369.1 - 1.1 9.3 3.4 1.5 8.9 0.2 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5392) RseC_MucC PF04246.12 GAM36369.1 - 2.5 8.1 4.0 2.4 8.1 1.1 2.3 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DEAD PF00270.29 GAM36370.1 - 1.5e-41 142.1 0.2 2.7e-41 141.3 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM36370.1 - 1.5e-33 115.5 0.1 6.5e-33 113.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 GAM36370.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM36370.1 - 0.0017 18.7 0.1 0.017 15.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 GAM36370.1 - 0.0045 17.0 0.0 0.0087 16.1 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 GAM36370.1 - 0.029 14.4 0.6 0.1 12.6 0.2 2.3 1 1 1 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 GAM36370.1 - 0.059 12.8 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 GAM36370.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 GAM36370.1 - 0.21 11.9 1.0 1.1 9.6 1.0 2.0 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.8 GAM36371.1 - 5.9e-73 244.6 0.7 2.2e-72 242.7 0.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 GAM36371.1 - 3.1e-24 85.3 0.1 9.4e-24 83.7 0.1 1.9 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DNA_ligase_A_M PF01068.21 GAM36371.1 - 6.3e-24 84.7 0.0 1.6e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAM36371.1 - 2.4e-20 73.6 0.0 1.2e-19 71.3 0.0 2.2 3 0 0 3 3 3 1 DNA ligase N terminus SF3a60_bindingd PF12108.8 GAM36371.1 - 2.4e-15 56.1 1.3 5.5e-15 54.9 1.3 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 GAM36371.1 - 1.9e-07 31.2 3.6 3.7e-07 30.3 1.8 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAM36371.1 - 3.3e-07 30.5 2.6 3.8e-06 27.1 1.1 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP9_N PF16958.5 GAM36371.1 - 0.00079 19.5 5.9 0.11 12.5 1.5 3.1 1 1 1 2 2 2 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_2 PF12756.7 GAM36371.1 - 0.0066 16.8 0.3 0.037 14.4 0.1 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) ANAPC8 PF04049.13 GAM36372.1 - 1.3e-54 184.0 0.6 3.6e-54 182.6 0.0 2.1 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 GAM36372.1 - 2.8e-19 67.7 11.8 1.8e-05 24.6 0.0 8.2 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAM36372.1 - 6e-19 67.0 7.0 0.00018 21.2 0.0 8.2 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM36372.1 - 5.6e-16 57.3 17.7 0.18 12.0 0.0 9.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAM36372.1 - 1.5e-09 38.2 13.8 0.13 12.8 0.0 8.1 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM36372.1 - 6.4e-09 35.4 2.4 1.1e-06 28.2 0.3 3.8 3 1 1 4 4 4 2 TPR repeat TPR_9 PF13371.6 GAM36372.1 - 1.5e-07 31.5 12.2 0.014 15.5 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM36372.1 - 1.7e-07 31.5 17.7 0.007 17.1 0.0 8.1 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM36372.1 - 2e-06 28.3 13.9 1.7e-05 25.4 0.0 6.7 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM36372.1 - 6.5e-05 23.0 5.0 7.6 7.2 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM36372.1 - 7.9e-05 22.8 14.4 0.15 12.3 0.1 6.1 6 1 2 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAM36372.1 - 0.00014 22.1 12.6 1.9 8.8 0.0 6.3 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAM36372.1 - 0.00037 19.8 1.9 0.00037 19.8 1.9 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM36372.1 - 0.00056 20.4 25.1 1.4 9.7 0.4 9.5 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM36372.1 - 0.0079 16.1 9.4 2.9 8.1 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat DUF4178 PF13785.6 GAM36372.1 - 0.029 14.5 1.0 0.25 11.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4178) ChAPs PF09295.10 GAM36372.1 - 0.099 11.6 0.1 6.3 5.7 0.0 2.7 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) CDC45 PF02724.14 GAM36372.1 - 0.74 8.0 4.8 1.1 7.4 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein TPR_10 PF13374.6 GAM36372.1 - 1.1 9.3 12.8 13 5.8 1.0 6.1 5 1 0 5 5 5 0 Tetratricopeptide repeat F-box-like PF12937.7 GAM36373.1 - 7.5e-07 28.9 1.7 6.1e-06 26.0 0.7 2.9 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 GAM36373.1 - 0.026 14.9 4.8 0.24 11.9 0.4 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box PF00646.33 GAM36373.1 - 0.13 12.2 0.5 21 5.1 0.2 2.8 2 0 0 2 2 2 0 F-box domain SR-25 PF10500.9 GAM36373.1 - 1.4 8.4 9.0 2.7 7.5 9.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AA_permease_2 PF13520.6 GAM36374.1 - 3.1e-42 144.9 14.5 3.8e-42 144.6 14.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM36374.1 - 4e-13 48.8 13.5 5.4e-13 48.4 13.5 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 GAM36374.1 - 0.01 14.6 0.2 0.01 14.6 0.2 2.8 2 1 1 3 3 3 1 Transmembrane amino acid transporter protein TMEM52 PF14979.6 GAM36374.1 - 0.74 9.7 2.1 1.5 8.7 2.1 1.6 1 1 0 1 1 1 0 Transmembrane 52 MPS-4 PF17523.2 GAM36374.1 - 3.9 7.7 7.0 1 9.5 1.0 2.8 3 0 0 3 3 3 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 polyprenyl_synt PF00348.17 GAM36376.1 - 1e-90 303.3 0.0 1.3e-90 303.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Mistic PF11458.8 GAM36376.1 - 0.16 11.9 2.0 0.41 10.6 0.1 2.6 3 1 1 4 4 4 0 Membrane-integrating protein Mistic ADH_zinc_N_2 PF13602.6 GAM36377.1 - 2.3e-15 57.8 0.1 6.1e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAM36377.1 - 5.8e-13 49.0 0.2 1.8e-12 47.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM36377.1 - 7.9e-10 38.6 1.1 1.9e-06 27.7 0.0 3.4 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 GAM36377.1 - 1.3e-05 24.7 0.1 2.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_2 PF16884.5 GAM36377.1 - 0.0028 17.5 0.1 0.043 13.7 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase Glycogen_syn PF05693.13 GAM36378.1 - 0 1154.4 0.0 0 1154.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 GAM36378.1 - 6.4e-05 23.0 0.2 0.00013 22.0 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 GAM36378.1 - 9.9e-05 22.8 0.0 0.066 13.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAM36378.1 - 0.0001 21.9 0.0 0.0049 16.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAM36378.1 - 0.00029 21.3 0.0 0.00064 20.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain MCM PF00493.23 GAM36380.1 - 4.7e-103 343.1 0.0 1e-102 342.0 0.0 1.6 1 0 0 1 1 1 1 MCM P-loop domain Vps54 PF07928.12 GAM36380.1 - 7.5e-51 172.1 0.7 6.1e-50 169.1 0.1 2.6 2 0 0 2 2 2 1 Vps54-like protein MCM_OB PF17207.3 GAM36380.1 - 5.3e-36 123.2 0.6 1.3e-35 122.0 0.6 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAM36380.1 - 2.3e-27 95.2 1.9 2.3e-27 95.2 1.9 2.8 3 0 0 3 3 3 1 MCM AAA-lid domain MCM_N PF14551.6 GAM36380.1 - 3e-15 56.7 0.2 1.3e-14 54.6 0.2 2.2 1 0 0 1 1 1 1 MCM N-terminal domain Vps54_N PF10475.9 GAM36380.1 - 2e-07 30.6 0.9 2e-07 30.6 0.9 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Mg_chelatase PF01078.21 GAM36380.1 - 1e-05 25.0 0.0 0.0027 17.1 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI DUF2451 PF10474.9 GAM36380.1 - 4.7e-05 23.3 0.2 0.00024 21.0 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) AAA_5 PF07728.14 GAM36380.1 - 0.00022 21.2 0.0 0.00058 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAM36380.1 - 0.0023 17.8 0.0 0.0061 16.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FliJ PF02050.16 GAM36380.1 - 0.017 15.3 1.5 0.075 13.3 1.5 2.2 1 0 0 1 1 1 0 Flagellar FliJ protein Nnf1 PF03980.14 GAM36380.1 - 0.023 15.1 0.3 0.11 12.9 0.3 2.2 1 0 0 1 1 1 0 Nnf1 PfkB PF00294.24 GAM36381.1 - 5.5e-32 111.3 0.3 8.4e-31 107.4 0.3 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Tau95 PF09734.9 GAM36383.1 - 4.8e-40 137.6 0.4 1.4e-39 136.1 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 GAM36383.1 - 2.5e-38 131.1 0.1 4.6e-38 130.3 0.1 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain DUF1350 PF07082.11 GAM36383.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) B56 PF01603.20 GAM36384.1 - 1.4e-191 637.0 2.1 1.7e-191 636.7 2.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) SOG2 PF10428.9 GAM36384.1 - 8.8 5.4 17.2 7.6 5.6 0.0 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein FAT PF02259.23 GAM36385.1 - 1e-76 258.4 8.4 2.7e-76 257.0 8.4 1.8 1 0 0 1 1 1 1 FAT domain AAA PF00004.29 GAM36385.1 - 1.5e-53 180.7 0.0 5.2e-38 130.5 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PI3_PI4_kinase PF00454.27 GAM36385.1 - 6.8e-36 124.3 0.0 2e-35 122.8 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase AAA_lid_3 PF17862.1 GAM36385.1 - 1.7e-08 34.2 0.0 4.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain CDC48_2 PF02933.17 GAM36385.1 - 8.9e-08 31.8 0.1 5.4e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 GAM36385.1 - 3.8e-07 30.4 0.1 0.0024 18.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 GAM36385.1 - 9.4e-07 29.4 0.3 0.036 14.5 0.0 4.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 GAM36385.1 - 1.2e-06 28.9 0.0 0.0017 18.7 0.0 4.1 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 GAM36385.1 - 2e-05 24.8 0.0 0.00059 20.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GAM36385.1 - 3e-05 23.8 0.0 0.24 11.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 GAM36385.1 - 5.6e-05 22.5 0.0 0.086 12.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 GAM36385.1 - 7.4e-05 22.2 0.1 0.036 13.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAM36385.1 - 0.00014 22.4 0.0 0.088 13.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain FATC PF02260.20 GAM36385.1 - 0.00014 21.6 0.1 0.00042 20.1 0.1 1.9 1 0 0 1 1 1 1 FATC domain RNA_helicase PF00910.22 GAM36385.1 - 0.00052 20.4 0.0 0.23 11.9 0.0 3.2 3 0 0 3 3 2 1 RNA helicase AAA_5 PF07728.14 GAM36385.1 - 0.00069 19.6 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 GAM36385.1 - 0.0023 18.0 0.0 3.4 7.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 GAM36385.1 - 0.0041 16.9 0.0 0.071 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain CDC48_N PF02359.18 GAM36385.1 - 0.0065 16.6 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_28 PF13521.6 GAM36385.1 - 0.0074 16.6 0.0 3.3 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 GAM36385.1 - 0.016 14.5 0.1 0.16 11.3 0.2 2.6 3 0 0 3 3 3 0 KaiC AAA_7 PF12775.7 GAM36385.1 - 0.017 14.7 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAM36385.1 - 0.031 14.0 0.0 0.74 9.5 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein TsaE PF02367.17 GAM36385.1 - 0.057 13.4 0.0 2 8.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 GAM36385.1 - 0.091 12.7 0.1 39 4.1 0.0 3.6 3 0 0 3 3 3 0 NACHT domain ABC_tran PF00005.27 GAM36385.1 - 0.095 13.2 0.1 0.38 11.3 0.1 2.1 1 0 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.17 GAM36385.1 - 0.13 11.3 0.0 2.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 GAM36385.1 - 0.14 12.6 0.1 34 4.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain TPR_2 PF07719.17 GAM36385.1 - 0.24 11.6 3.2 8.4 6.8 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF572 PF04502.13 GAM36386.1 - 4.3e-71 240.2 13.9 5.1e-71 240.0 13.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) TF_Zn_Ribbon PF08271.12 GAM36386.1 - 0.65 9.6 5.4 2.4 7.7 1.3 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Zn_ribbon_SprT PF17283.2 GAM36386.1 - 0.71 9.8 3.8 0.72 9.8 2.2 1.8 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf-ACC PF17848.1 GAM36386.1 - 1.2 9.2 4.9 2.5 8.2 0.5 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain TPR_1 PF00515.28 GAM36387.1 - 1.2e-28 97.7 8.0 7.2e-05 22.4 0.8 9.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAM36387.1 - 1.1e-27 93.9 17.9 0.00018 21.4 0.0 10.3 10 0 0 10 10 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM36387.1 - 2.4e-25 88.5 17.9 2.1e-19 69.5 1.2 6.1 6 1 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAM36387.1 - 5.9e-18 65.1 11.4 0.00048 20.6 0.1 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 GAM36387.1 - 1.4e-16 60.5 22.9 1.4e-08 34.9 0.1 8.8 7 3 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAM36387.1 - 1.5e-16 59.1 7.1 0.027 14.7 0.1 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAM36387.1 - 2.7e-13 49.5 17.3 0.39 11.6 0.1 9.2 8 2 2 10 10 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAM36387.1 - 3e-12 46.0 13.4 0.00015 21.5 0.1 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM36387.1 - 2.3e-10 40.0 11.0 0.37 10.5 0.1 8.7 9 0 0 9 9 9 3 TPR repeat TPR_16 PF13432.6 GAM36387.1 - 8.1e-10 39.2 27.7 0.074 13.7 0.0 8.8 8 1 2 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAM36387.1 - 1.2e-08 34.4 16.4 0.21 11.7 0.0 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAM36387.1 - 7e-08 32.6 11.2 0.31 11.8 0.3 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAM36387.1 - 0.0004 20.7 8.4 9.2 7.2 0.4 7.5 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAM36387.1 - 0.00078 19.7 12.2 5 7.7 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat RPN7 PF10602.9 GAM36387.1 - 0.0066 16.2 0.7 35 4.0 0.0 5.0 3 1 1 5 5 5 0 26S proteasome subunit RPN7 TPR_MalT PF17874.1 GAM36387.1 - 0.0097 15.3 9.9 0.46 9.8 0.2 4.3 5 1 0 5 5 5 2 MalT-like TPR region TPR_21 PF09976.9 GAM36387.1 - 0.019 14.7 2.9 2.9 7.6 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain SRP_TPR_like PF17004.5 GAM36387.1 - 0.035 14.1 0.1 0.26 11.3 0.0 2.5 2 0 0 2 2 2 0 Putative TPR-like repeat TPR_9 PF13371.6 GAM36387.1 - 0.055 13.6 18.6 4.9 7.4 0.0 6.5 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 GAM36387.1 - 0.68 10.0 8.7 0.8 9.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 GAM36388.1 - 6.2e-44 150.4 28.1 6.2e-44 150.4 28.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM36388.1 - 3.4e-09 36.1 17.8 4.6e-08 32.4 17.8 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 GAM36388.1 - 5.3e-09 35.1 1.7 8.1e-09 34.4 1.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2178 PF09946.9 GAM36388.1 - 0.61 10.3 5.0 17 5.6 1.2 3.3 3 1 0 3 3 3 0 Predicted membrane protein (DUF2178) GATase_5 PF13507.6 GAM36389.1 - 4.8e-101 337.2 0.0 7e-101 336.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 GAM36389.1 - 3.7e-39 134.3 0.5 1.4e-24 87.0 0.3 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 GAM36389.1 - 5e-34 116.7 0.0 1.6e-33 115.1 0.0 1.9 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 GAM36389.1 - 1e-21 77.2 0.0 2.2e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain SpdB PF05122.13 GAM36389.1 - 0.025 14.7 0.1 0.065 13.4 0.1 1.6 1 0 0 1 1 1 0 Mobile element transfer protein TruB_C PF09142.11 GAM36389.1 - 0.15 11.8 0.6 5.9 6.7 0.0 3.1 3 0 0 3 3 3 0 tRNA Pseudouridine synthase II, C terminal GCP_N_terminal PF17681.1 GAM36390.1 - 1.4e-33 116.9 1.4 3.2e-33 115.7 1.4 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 GAM36390.1 - 9.3e-26 91.0 0.1 1.6e-25 90.2 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 GAM36390.1 - 9.5e-08 30.9 0.0 1.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 MBA1 PF07961.11 GAM36390.1 - 0.0081 15.2 0.0 0.018 14.1 0.0 1.6 1 0 0 1 1 1 1 MBA1-like protein Glyco_transf_15 PF01793.16 GAM36391.1 - 6e-115 383.9 8.1 7.2e-115 383.7 8.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase COX5A PF02284.16 GAM36392.1 - 5.4e-38 129.1 0.2 7.2e-38 128.7 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ELO PF01151.18 GAM36393.1 - 9.9e-63 212.0 23.3 1.2e-62 211.8 23.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PNTB PF02233.16 GAM36395.1 - 1.1e-172 575.1 25.7 1.1e-172 575.1 25.7 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 GAM36395.1 - 8.9e-71 237.6 0.1 4.3e-70 235.3 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 GAM36395.1 - 3.3e-46 157.0 0.0 6.9e-46 155.9 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 GAM36395.1 - 9.4e-30 102.9 3.9 9.4e-30 102.9 3.9 4.8 4 1 1 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch Peptidase_M19 PF01244.21 GAM36395.1 - 8.9e-17 61.2 0.2 2.4e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 Membrane dipeptidase (Peptidase family M19) Pyr_redox_2 PF07992.14 GAM36395.1 - 0.011 15.0 0.4 0.029 13.6 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 GAM36395.1 - 0.019 14.3 0.1 2.1 7.7 0.0 2.9 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 GAM36395.1 - 0.02 14.6 0.3 0.087 12.6 0.3 2.1 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain CoA_binding PF02629.19 GAM36395.1 - 0.027 15.1 4.7 0.8 10.4 1.0 3.3 2 1 0 2 2 2 0 CoA binding domain NAD_binding_8 PF13450.6 GAM36395.1 - 0.33 11.2 3.9 0.15 12.3 0.4 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ADH_zinc_N PF00107.26 GAM36395.1 - 0.44 10.5 3.2 1.3 9.0 0.1 2.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PRIMA1 PF16101.5 GAM36395.1 - 0.98 9.5 4.5 0.82 9.7 2.4 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 MIOX PF05153.15 GAM36396.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol oxygenase Fungal_trans PF04082.18 GAM36397.1 - 3.1e-06 26.4 0.1 4.7e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alpha-L-AF_C PF06964.12 GAM36398.1 - 3.7e-16 59.7 0.2 6.5e-16 58.9 0.2 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_79C PF16862.5 GAM36398.1 - 0.22 12.4 4.0 0.19 12.6 1.4 2.2 2 1 0 2 2 2 0 Glycosyl hydrolase family 79 C-terminal beta domain Bac_rhamnosid6H PF17389.2 GAM36399.1 - 1.5e-128 428.8 0.0 2e-128 428.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 GAM36399.1 - 1.6e-53 181.0 0.0 2.6e-53 180.3 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 GAM36399.1 - 2.1e-22 79.0 0.0 3.6e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 GAM36399.1 - 1.5e-13 50.3 0.0 3.1e-12 46.1 0.0 2.4 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Sugar_tr PF00083.24 GAM36400.1 - 6.3e-90 302.2 24.3 7.3e-90 302.0 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM36400.1 - 3.5e-23 82.1 35.8 8.9e-17 61.0 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_127 PF07944.12 GAM36401.1 - 2e-21 76.1 0.0 2.9e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 adh_short PF00106.25 GAM36402.1 - 2.4e-23 82.6 0.0 5.9e-21 74.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM36402.1 - 5.1e-17 62.2 0.0 6.6e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM36402.1 - 2.6e-09 37.3 0.2 4.7e-09 36.4 0.2 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 GAM36402.1 - 0.001 19.0 0.2 0.0015 18.4 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 GAM36402.1 - 0.0011 18.3 0.1 0.0017 17.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 GAM36402.1 - 0.088 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Gly_rich_SFCGS PF14272.6 GAM36402.1 - 0.11 12.6 0.3 0.17 11.9 0.3 1.4 1 0 0 1 1 1 0 Glycine-rich SFCGS 2-Hacid_dh_C PF02826.19 GAM36402.1 - 0.17 11.2 0.1 0.3 10.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AA_permease_2 PF13520.6 GAM36403.1 - 5.2e-44 150.7 49.9 6.7e-44 150.4 49.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM36403.1 - 1.4e-18 66.8 37.2 2e-18 66.3 37.2 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_oxidored PF12831.7 GAM36404.1 - 3.7e-64 217.7 0.0 4.4e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Sugar_tr PF00083.24 GAM36405.1 - 2.7e-79 267.1 11.3 4.1e-77 260.0 11.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM36405.1 - 4.4e-14 52.2 19.8 4.5e-08 32.4 2.2 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily EBP PF05241.12 GAM36405.1 - 0.063 12.7 1.0 0.15 11.5 1.0 1.6 1 0 0 1 1 1 0 Emopamil binding protein UPF0444 PF15475.6 GAM36405.1 - 8.7 6.7 7.1 1.5 9.1 0.5 2.3 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 Pyr_redox_2 PF07992.14 GAM36406.1 - 2.5e-41 141.8 1.0 3.2e-41 141.5 1.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM36406.1 - 1.9e-13 50.8 1.6 1.1e-10 42.0 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM36406.1 - 5.3e-12 45.6 2.0 1.1e-09 38.0 1.2 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM36406.1 - 1.2e-07 31.1 4.6 0.013 14.6 0.1 3.6 3 1 1 4 4 4 3 Lycopene cyclase protein NAD_binding_9 PF13454.6 GAM36406.1 - 9.9e-07 28.9 0.5 0.93 9.5 0.1 3.6 3 0 0 3 3 3 3 FAD-NAD(P)-binding Thi4 PF01946.17 GAM36406.1 - 0.00058 19.2 1.5 0.04 13.2 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 GAM36406.1 - 0.00094 18.6 1.2 0.041 13.2 0.1 2.1 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 GAM36406.1 - 0.0018 17.9 8.6 0.84 9.1 0.0 3.8 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAM36406.1 - 0.012 14.8 2.7 3.5 6.7 0.3 3.5 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF5130 PF17174.4 GAM36406.1 - 0.044 14.0 0.2 0.094 12.9 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5130) HI0933_like PF03486.14 GAM36406.1 - 0.083 11.6 12.3 0.16 10.6 0.5 3.4 3 1 1 4 4 4 0 HI0933-like protein ApbA PF02558.16 GAM36406.1 - 0.089 12.4 0.1 0.44 10.2 0.1 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 GAM36406.1 - 0.096 11.5 3.0 12 4.6 0.0 3.3 4 0 0 4 4 4 0 Tryptophan halogenase DEAD PF00270.29 GAM36406.1 - 0.16 11.7 2.3 0.85 9.4 2.8 2.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase Aldo_ket_red PF00248.21 GAM36407.1 - 6.1e-49 166.8 0.0 6.2e-32 111.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Phage_ABA_S PF18066.1 GAM36407.1 - 0.031 15.0 0.4 0.16 12.7 0.0 2.3 2 1 0 2 2 2 0 Phage ABA sandwich domain DUF1996 PF09362.10 GAM36408.1 - 4e-77 259.4 0.2 5.2e-77 259.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NmrA PF05368.13 GAM36409.1 - 1.3e-73 247.4 0.0 1.6e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family DUF1876 PF08962.11 GAM36409.1 - 0.06 13.3 0.4 0.15 12.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) F-box-like PF12937.7 GAM36410.1 - 0.0068 16.3 0.0 0.024 14.5 0.0 2.0 1 0 0 1 1 1 1 F-box-like Endonuc-BsobI PF09194.10 GAM36410.1 - 0.13 11.4 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease BsobI Asparaginase PF00710.20 GAM36411.1 - 2.3e-58 196.9 0.0 3.3e-58 196.4 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 GAM36411.1 - 2.2e-26 92.3 0.1 4.9e-26 91.2 0.1 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 GAM36411.1 - 1.4e-10 41.6 0.1 5.4e-10 39.7 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM36411.1 - 2.9e-09 37.3 0.1 7.7e-06 26.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM36411.1 - 6.5e-09 35.3 0.3 0.0092 16.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 GAM36411.1 - 1.2e-08 35.0 1.2 0.00047 20.5 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAM36411.1 - 2.5e-08 34.0 0.0 2.9e-07 30.6 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) NAP PF00956.18 GAM36412.1 - 1.3e-26 93.4 11.8 2.5e-24 85.9 8.2 2.4 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) AIM3 PF17096.5 GAM36412.1 - 0.058 14.3 0.7 0.24 12.4 0.0 2.1 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 BT1 PF03092.16 GAM36412.1 - 0.28 9.4 0.6 0.38 8.9 0.6 1.2 1 0 0 1 1 1 0 BT1 family Syntaxin-6_N PF09177.11 GAM36413.1 - 7.5e-26 90.6 0.3 3.3e-25 88.5 0.1 2.0 2 0 0 2 2 2 1 Syntaxin 6, N-terminal Cnn_1N PF07989.11 GAM36413.1 - 0.023 14.8 1.5 0.76 10.0 0.0 2.6 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF4164 PF13747.6 GAM36413.1 - 0.05 13.9 6.0 2.2 8.6 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) DUF5132 PF17195.4 GAM36413.1 - 0.11 12.5 0.8 5.4 7.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) DUF883 PF05957.13 GAM36413.1 - 0.12 13.0 1.2 4.2 8.1 0.0 3.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) APG6_N PF17675.1 GAM36413.1 - 0.16 12.5 4.4 7.8 7.0 0.8 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF2730 PF10805.8 GAM36413.1 - 0.17 12.0 1.0 22 5.2 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Phage_int_SAM_2 PF12834.7 GAM36413.1 - 0.21 12.3 0.4 1.2 9.8 0.1 2.3 3 0 0 3 3 3 0 Phage integrase, N-terminal MbeB_N PF04837.12 GAM36413.1 - 0.55 10.6 2.5 0.62 10.4 0.1 2.3 3 0 0 3 3 3 0 MbeB-like, N-term conserved region SlyX PF04102.12 GAM36413.1 - 1.4 9.6 8.0 29 5.4 1.6 3.4 3 0 0 3 3 3 0 SlyX NPV_P10 PF05531.12 GAM36413.1 - 2.6 8.5 5.6 51 4.4 0.1 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Methyltransf_32 PF13679.6 GAM36415.1 - 3.8e-22 79.0 0.7 1.4e-21 77.1 0.7 1.8 1 1 0 1 1 1 1 Methyltransferase domain Med1 PF10744.9 GAM36417.1 - 1.5e-124 416.3 0.0 2.7e-124 415.4 0.0 1.4 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 Gln-synt_C PF00120.24 GAM36418.1 - 3.7e-16 59.0 0.0 2e-13 50.1 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GAM36418.1 - 5e-13 48.6 0.0 8.8e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Sugar_tr PF00083.24 GAM36419.1 - 8.9e-111 370.9 24.3 1.1e-110 370.6 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM36419.1 - 1.4e-15 57.1 39.0 1.9e-14 53.4 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAM36419.1 - 1.6e-06 26.7 2.3 1.6e-06 26.7 2.3 1.9 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family zf-CCHC PF00098.23 GAM36420.1 - 1.5e-58 192.4 98.9 1.3e-07 31.3 2.7 11.2 11 0 0 11 11 11 11 Zinc knuckle 3HCDH_N PF02737.18 GAM36420.1 - 1.4e-19 70.7 0.0 2.7e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-CCHC_4 PF14392.6 GAM36420.1 - 2.4e-11 43.2 63.3 0.0048 16.6 0.1 11.0 11 0 0 11 11 11 7 Zinc knuckle zf-CCHC_2 PF13696.6 GAM36420.1 - 1e-09 38.0 79.8 4.9e-05 23.1 1.4 10.9 11 0 0 11 11 11 7 Zinc knuckle 3HCDH PF00725.22 GAM36420.1 - 1.4e-09 38.5 0.0 2.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain zf-CCHC_3 PF13917.6 GAM36420.1 - 5.8e-09 35.8 72.1 0.043 13.8 0.9 11.1 2 2 9 11 11 11 9 Zinc knuckle zf-CCHC_6 PF15288.6 GAM36420.1 - 0.0018 18.1 0.5 0.0018 18.1 0.5 11.0 11 0 0 11 11 11 4 Zinc knuckle Acetyltransf_10 PF13673.7 GAM36421.1 - 2.3e-10 40.5 0.0 3.3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM36421.1 - 5e-09 36.4 0.0 7.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM36421.1 - 3.5e-06 27.4 0.0 6.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAM36421.1 - 0.0003 20.9 0.0 0.00048 20.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM36421.1 - 0.0026 17.8 0.2 0.015 15.4 0.2 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Actin PF00022.19 GAM36422.1 - 1.1e-128 429.4 0.0 5.4e-128 427.1 0.0 1.8 1 1 0 1 1 1 1 Actin Peptidase_M24_C PF16188.5 GAM36422.1 - 0.12 12.4 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 DUF4332 PF14229.6 GAM36422.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Glyco_tran_28_C PF04101.16 GAM36423.1 - 7e-19 68.4 0.0 3.8e-18 66.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 GAM36423.1 - 0.0037 16.1 0.0 0.0049 15.7 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ECH_1 PF00378.20 GAM36423.1 - 0.13 11.5 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase MRP-S28 PF10213.9 GAM36424.1 - 1.6e-45 154.6 0.2 5.4e-45 152.9 0.2 1.9 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Phage_TAC_10 PF10963.8 GAM36424.1 - 0.11 12.7 0.0 0.38 11.0 0.0 1.9 1 0 0 1 1 1 0 Phage tail assembly chaperone Pol_alpha_B_N PF08418.10 GAM36425.1 - 0.0077 16.2 0.6 0.016 15.2 0.0 1.6 1 1 1 2 2 2 1 DNA polymerase alpha subunit B N-terminal Chlam_PMP PF02415.17 GAM36425.1 - 0.74 10.4 4.2 13 6.5 0.4 3.5 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat zf-PHD-like PF15446.6 GAM36426.1 - 1.8e-68 229.4 13.9 3.8e-68 228.4 13.9 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 GAM36426.1 - 9.8e-53 179.1 0.1 1.6e-52 178.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 GAM36426.1 - 1.1e-24 86.0 0.4 3.1e-24 84.6 0.4 1.9 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 GAM36426.1 - 3.2e-19 69.3 0.0 8.1e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 GAM36426.1 - 3.1e-11 43.0 3.7 6.4e-11 42.0 3.7 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 GAM36426.1 - 2.9e-07 30.3 13.7 9.4e-06 25.4 5.2 3.4 2 1 0 2 2 2 2 PHD-finger Chromo PF00385.24 GAM36426.1 - 2.3e-05 24.2 5.5 0.052 13.5 2.0 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF1087 PF06465.13 GAM36426.1 - 0.00023 21.1 0.5 0.00099 19.1 0.0 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1087) ResIII PF04851.15 GAM36426.1 - 0.011 15.7 0.0 0.042 13.8 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Pep1_7 PF17232.2 GAM36426.1 - 1.2 9.6 8.5 0.51 10.8 2.2 3.3 2 0 0 2 2 2 0 Elicitor peptide 1-7 C1_1 PF00130.22 GAM36426.1 - 2.2 8.2 15.5 1.3 9.0 2.7 3.6 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SpoU_methylase PF00588.19 GAM36427.1 - 1.8e-24 86.5 0.2 1.5e-23 83.5 0.2 2.2 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 GAM36427.1 - 1.1e-07 32.1 0.0 2.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Asp PF00026.23 GAM36428.1 - 1.5e-67 228.3 6.3 1.9e-67 228.0 6.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM36428.1 - 2.5e-13 50.7 0.8 1.2e-11 45.2 0.8 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAM36428.1 - 6.6e-06 26.7 3.4 0.056 14.1 0.3 3.0 3 1 1 4 4 4 2 Aspartyl protease NAD_binding_4 PF07993.12 GAM36429.1 - 2.3e-18 66.3 0.0 3.7e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 GAM36429.1 - 4.2e-06 26.4 0.0 6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 GAM36430.1 - 5.8e-44 150.4 46.2 3e-43 148.1 46.2 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM36430.1 - 3e-15 55.7 16.1 5.6e-15 54.8 16.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM36430.1 - 5.5e-10 38.7 15.9 5.5e-10 38.7 15.9 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter Ank_2 PF12796.7 GAM36431.1 - 2.9e-59 197.6 9.6 4.3e-12 46.5 0.1 8.8 3 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM36431.1 - 1.1e-47 159.8 21.6 1.1e-07 32.2 0.1 12.8 5 4 10 15 15 15 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM36431.1 - 2.4e-45 152.0 25.7 1.3e-09 38.2 0.1 11.4 8 2 3 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM36431.1 - 1e-43 142.2 15.2 0.00057 20.1 0.0 16.0 16 0 0 16 16 16 7 Ankyrin repeat Ank PF00023.30 GAM36431.1 - 7.1e-42 140.1 14.1 0.00037 20.8 0.0 14.5 15 1 0 15 15 15 9 Ankyrin repeat AAA_22 PF13401.6 GAM36431.1 - 3.9e-07 30.4 0.1 2.7e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAM36431.1 - 5.4e-07 29.7 1.6 5.1e-05 23.3 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 GAM36431.1 - 0.00035 21.0 0.3 0.0014 19.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Helo_like_N PF17111.5 GAM36431.1 - 0.00055 19.4 0.2 0.0012 18.2 0.2 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 GAM36431.1 - 0.00093 19.4 0.6 0.0027 17.9 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA PF00004.29 GAM36431.1 - 0.049 14.1 0.0 0.68 10.4 0.0 2.5 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sec34 PF04136.15 GAM36431.1 - 0.082 12.8 0.2 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 Sec34-like family RuvB_N PF05496.12 GAM36431.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain cobW PF02492.19 GAM36431.1 - 0.12 12.0 0.0 19 4.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF668 PF05003.12 GAM36431.1 - 0.14 12.6 0.5 6.2 7.4 0.2 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF668) SNF2_N PF00176.23 GAM36432.1 - 2e-75 253.7 0.2 3.5e-75 252.9 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 GAM36432.1 - 1.7e-40 137.6 2.5 8.2e-40 135.4 2.5 2.3 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 GAM36432.1 - 4e-38 130.6 0.7 4e-38 130.6 0.7 4.0 5 0 0 5 5 3 1 HAND Helicase_C PF00271.31 GAM36432.1 - 2.6e-18 66.4 0.4 3.2e-17 62.9 0.0 2.8 3 0 0 3 3 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM36432.1 - 5.1e-11 42.9 1.7 1.4e-10 41.5 0.0 2.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 GAM36432.1 - 2e-07 30.5 0.0 7e-07 28.7 0.0 1.9 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 GAM36432.1 - 0.00028 20.7 0.0 0.00083 19.2 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 GAM36432.1 - 0.00029 20.6 0.0 0.0011 18.7 0.0 2.0 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 GAM36432.1 - 0.018 14.3 0.3 0.043 13.0 0.3 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_14 PF13173.6 GAM36432.1 - 0.019 15.0 0.0 0.099 12.7 0.0 2.3 1 0 0 1 1 1 0 AAA domain Myb_DNA-binding PF00249.31 GAM36432.1 - 0.026 14.7 0.2 3 8.1 0.0 2.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain DEAD_2 PF06733.15 GAM36432.1 - 0.034 13.8 0.1 0.082 12.5 0.1 1.6 1 0 0 1 1 1 0 DEAD_2 Sporozoite_P67 PF05642.11 GAM36432.1 - 0.3 9.1 8.4 0.49 8.4 8.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4588 PF15251.6 GAM36433.1 - 4.3e-08 33.2 0.0 9.7e-08 32.1 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Adap_comp_sub PF00928.21 GAM36434.1 - 1.5e-59 201.6 0.0 2.5e-59 200.8 0.0 1.4 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAM36434.1 - 0.00019 21.4 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Med3 PF11593.8 GAM36434.1 - 0.2 10.8 5.5 0.34 10.0 5.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Rrn6 PF10214.9 GAM36434.1 - 0.51 8.8 10.8 0.73 8.2 10.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor NST1 PF13945.6 GAM36434.1 - 8.7 6.4 9.3 13 5.8 9.3 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Aldedh PF00171.22 GAM36435.1 - 8.5e-74 248.7 0.0 1.1e-73 248.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PIG-H PF10181.9 GAM36435.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component p450 PF00067.22 GAM36436.1 - 9.8e-68 229.0 0.0 1.1e-67 228.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HgmA PF04209.13 GAM36437.1 - 2e-195 649.4 0.1 2.3e-195 649.2 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.18 GAM36438.1 - 1.7e-56 191.3 0.0 2.3e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 GAM36438.1 - 2.8e-30 104.7 0.0 4.9e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Fungal_trans PF04082.18 GAM36439.1 - 5.2e-13 48.6 0.0 1e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain PDU_like PF15953.5 GAM36439.1 - 0.0021 18.2 0.3 0.13 12.3 0.1 2.6 2 0 0 2 2 2 1 Putative propanediol utilisation DUF16 PF01519.16 GAM36439.1 - 0.23 12.0 1.2 0.8 10.2 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 ICL PF00463.21 GAM36440.1 - 2e-293 973.7 2.2 2.3e-293 973.5 2.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 GAM36440.1 - 6.2e-12 45.5 0.0 2.7e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Trehalase PF01204.18 GAM36441.1 - 1.1e-185 618.4 0.0 1.4e-185 618.0 0.0 1.1 1 0 0 1 1 1 1 Trehalase adh_short_C2 PF13561.6 GAM36441.1 - 2.8e-48 164.5 0.0 4e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM36441.1 - 2.1e-44 151.3 0.0 3.4e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Trehalase_Ca-bi PF07492.11 GAM36441.1 - 6.1e-11 41.8 0.1 1.1e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain KR PF08659.10 GAM36441.1 - 6.9e-07 29.4 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 KR domain OTU PF02338.19 GAM36442.1 - 2.1e-22 80.0 0.3 1.2e-17 64.6 0.0 2.5 3 0 0 3 3 3 2 OTU-like cysteine protease Peptidase_C65 PF10275.9 GAM36442.1 - 1.1e-05 25.0 0.6 0.0021 17.5 0.0 2.9 3 1 0 3 3 3 2 Peptidase C65 Otubain mCpol PF18182.1 GAM36442.1 - 0.078 13.3 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 minimal CRISPR polymerase domain HU-CCDC81_bac_2 PF18175.1 GAM36442.1 - 2.9 7.8 4.2 1.4 8.9 0.6 2.2 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 TPMT PF05724.11 GAM36443.1 - 3.3e-24 85.8 0.0 5.6e-24 85.0 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 GAM36443.1 - 3.6e-07 30.7 0.0 8.1e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM36443.1 - 7e-07 29.2 0.0 9.9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM36443.1 - 2.6e-06 27.3 0.0 5.8e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM36443.1 - 6.5e-06 26.8 0.0 1.6e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM36443.1 - 0.0066 17.2 0.0 0.018 15.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 GAM36443.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB AdoMet_MTase PF07757.13 GAM36443.1 - 0.19 12.1 0.3 0.52 10.7 0.3 1.7 1 1 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MFS_1 PF07690.16 GAM36444.1 - 5.3e-44 150.6 38.9 2.2e-43 148.5 32.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zip PF02535.22 GAM36444.1 - 0.12 11.6 3.7 0.67 9.1 0.0 2.7 3 0 0 3 3 3 0 ZIP Zinc transporter G_glu_transpept PF01019.21 GAM36446.1 - 5.8e-140 467.5 0.0 6.6e-140 467.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Pollen_allerg_2 PF01620.16 GAM36446.1 - 1.3 9.2 5.6 2.6 8.2 5.6 1.5 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) Fungal_trans PF04082.18 GAM36447.1 - 7.8e-12 44.8 0.6 1.6e-11 43.8 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Form_Nir_trans PF01226.17 GAM36449.1 - 1.6e-71 240.4 19.9 1.8e-71 240.2 19.9 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF2107 PF09880.9 GAM36449.1 - 0.013 15.6 0.1 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2107) UPF0016 PF01169.19 GAM36449.1 - 0.26 11.6 0.1 0.26 11.6 0.1 3.3 2 1 2 4 4 4 0 Uncharacterized protein family UPF0016 tRNA-synt_2b PF00587.25 GAM36452.1 - 1.2e-31 110.1 0.0 3.3e-29 102.1 0.0 2.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAM36452.1 - 3.5e-16 59.1 0.1 8.8e-16 57.8 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 GAM36452.1 - 2.3e-13 50.0 0.0 4.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 GAM36452.1 - 0.004 17.2 0.0 0.0095 16.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.14 GAM36453.1 - 3e-37 127.8 0.1 4.5e-37 127.2 0.1 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.21 GAM36453.1 - 1.5e-12 48.1 0.0 4e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase FRQ PF09421.10 GAM36454.1 - 3.2e-32 111.6 23.5 4.4e-26 91.3 2.1 3.0 1 1 1 2 2 2 2 Frequency clock protein WSC PF01822.19 GAM36454.1 - 4.7e-11 42.7 10.6 1.4e-10 41.2 10.6 1.9 1 0 0 1 1 1 1 WSC domain Metallothio PF00131.20 GAM36454.1 - 0.064 13.4 3.2 0.14 12.3 3.2 1.5 1 0 0 1 1 1 0 Metallothionein CoA_trans PF01144.23 GAM36455.1 - 3.3e-105 350.3 1.8 2.2e-65 220.1 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF2370 PF10176.9 GAM36457.1 - 1e-92 309.9 0.0 1.5e-92 309.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Nha1_C PF08619.10 GAM36457.1 - 0.0011 18.3 2.4 0.0012 18.1 2.4 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus DUF4719 PF15843.5 GAM36457.1 - 0.046 13.8 0.9 0.088 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) ASFV_J13L PF05568.11 GAM36458.1 - 0.0069 16.2 4.1 0.015 15.0 4.1 1.7 1 0 0 1 1 1 1 African swine fever virus J13L protein MGC-24 PF05283.11 GAM36458.1 - 0.2 12.1 3.7 0.36 11.3 3.7 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin APG9 PF04109.16 GAM36459.1 - 1.7e-189 630.8 10.0 5.7e-167 556.6 3.7 2.0 1 1 1 2 2 2 2 Autophagy protein Apg9 RasGAP PF00616.19 GAM36460.1 - 3.9e-30 105.1 0.0 3.7e-21 75.8 0.0 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 GAM36460.1 - 5.5e-08 33.0 0.3 6.7e-07 29.5 0.3 2.4 1 1 0 1 1 1 1 C2 domain WD40 PF00400.32 GAM36461.1 - 1.5e-07 31.9 0.2 1.5 9.8 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat COQ9 PF08511.11 GAM36462.1 - 5.2e-27 93.4 0.0 8.7e-27 92.7 0.0 1.4 1 0 0 1 1 1 1 COQ9 2-oxogl_dehyd_N PF16078.5 GAM36462.1 - 0.14 11.8 0.3 0.27 10.9 0.3 1.4 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus RRM_1 PF00076.22 GAM36463.1 - 5.4e-51 170.3 0.0 5.2e-17 61.4 0.0 4.3 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM36463.1 - 0.00027 20.5 0.0 0.15 11.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 GAM36463.1 - 0.0013 18.8 0.0 6.1 7.0 0.0 4.2 4 1 0 4 4 4 1 Limkain b1 RRM_3 PF08777.11 GAM36463.1 - 0.0015 18.5 0.0 2.6 8.2 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif PH PF00169.29 GAM36466.1 - 0.00021 21.7 0.1 0.00081 19.9 0.0 2.1 2 0 0 2 2 2 1 PH domain DUF3921 PF13060.6 GAM36466.1 - 0.055 13.5 0.1 0.17 12.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) DUF5344 PF17279.2 GAM36466.1 - 0.12 13.0 0.7 1.7 9.3 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Tim17 PF02466.19 GAM36467.1 - 0.011 16.0 6.9 0.054 13.9 6.8 2.2 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family RPT PF13446.6 GAM36468.1 - 9.6e-57 188.8 0.3 3e-20 71.9 0.0 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 GAM36468.1 - 9.7e-41 140.0 0.1 3.9e-40 138.0 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM36468.1 - 0.0011 18.7 3.7 0.013 15.2 3.7 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WRKY PF03106.15 GAM36468.1 - 0.016 15.4 0.0 0.3 11.4 0.0 2.5 2 0 0 2 2 2 0 WRKY DNA -binding domain Pkinase PF00069.25 GAM36469.1 - 7.1e-68 228.8 0.0 9.1e-68 228.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM36469.1 - 1.7e-31 109.5 0.0 2.8e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAM36469.1 - 0.0085 15.1 0.0 0.016 14.1 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAM36469.1 - 0.039 13.3 0.1 0.082 12.2 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM36469.1 - 0.052 13.5 0.4 0.17 11.8 0.0 1.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family DIT1_PvcA PF05141.12 GAM36472.1 - 2.1e-85 286.6 0.0 2.8e-85 286.1 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 GAM36472.1 - 6.6e-16 58.9 0.0 1.4e-15 57.9 0.0 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAHP_snth_FXD PF18152.1 GAM36472.1 - 0.19 11.6 0.0 0.45 10.4 0.0 1.6 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain FAD_binding_3 PF01494.19 GAM36473.1 - 1.7e-58 198.5 0.0 2.4e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 GAM36473.1 - 0.00025 20.4 0.6 0.00057 19.2 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM36473.1 - 0.00034 20.8 0.3 0.0014 18.8 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM36473.1 - 0.00058 19.1 0.3 0.001 18.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM36473.1 - 0.00062 19.5 0.7 0.0038 16.8 0.4 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM36473.1 - 0.00064 18.5 0.2 0.0014 17.4 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 GAM36473.1 - 0.00099 18.6 0.4 0.0016 17.9 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM36473.1 - 0.0014 19.1 0.0 0.0065 17.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM36473.1 - 0.0015 17.8 0.1 0.0039 16.5 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM36473.1 - 0.0018 17.5 0.1 0.0097 15.2 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 GAM36473.1 - 0.0029 16.7 0.8 0.0056 15.8 0.1 1.8 3 0 0 3 3 3 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 GAM36473.1 - 0.004 16.5 0.0 0.0077 15.6 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 GAM36473.1 - 0.041 12.7 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 GAM36473.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A XdhC_C PF13478.6 GAM36473.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.18 GAM36473.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SAT PF16073.5 GAM36474.1 - 2e-40 139.0 0.3 2.4e-40 138.8 0.3 1.0 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis adh_short_C2 PF13561.6 GAM36475.1 - 3.2e-33 115.2 0.0 7.9e-33 114.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM36475.1 - 5.3e-33 114.1 0.1 5.2e-32 110.9 0.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAM36475.1 - 1.4e-07 31.6 0.0 2.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM36475.1 - 0.00024 20.6 0.1 0.001 18.6 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM36475.1 - 0.0024 16.9 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAM36475.1 - 0.068 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YCII PF03795.14 GAM36476.1 - 2e-06 28.1 0.0 2.3e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain AAA_18 PF13238.6 GAM36476.1 - 0.096 13.2 0.0 0.099 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain Dabb PF07876.12 GAM36477.1 - 3.7e-11 43.5 0.0 4.2e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Whirly PF08536.11 GAM36477.1 - 0.054 13.3 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Whirly transcription factor ADH_zinc_N PF00107.26 GAM36478.1 - 1.4e-25 89.7 0.1 2.5e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM36478.1 - 4.5e-17 63.4 0.1 7.2e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM36478.1 - 5.9e-07 29.3 0.1 2.3e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain FAD_binding_3 PF01494.19 GAM36479.1 - 1.5e-51 175.7 0.0 2e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAM36479.1 - 2.3e-05 24.5 0.0 7.9e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.10 GAM36479.1 - 0.11 11.5 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase Aminotran_4 PF01063.19 GAM36480.1 - 1.9e-20 73.7 0.0 2.3e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV CoA_transf_3 PF02515.17 GAM36481.1 - 2.7e-37 128.7 0.0 1.3e-36 126.5 0.0 1.9 2 0 0 2 2 2 1 CoA-transferase family III Glyco_hydro_47 PF01532.20 GAM36482.1 - 8.7e-185 615.0 0.1 8.7e-185 615.0 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 DUF2013 PF09431.10 GAM36482.1 - 4.1e-47 159.8 0.3 4.1e-47 159.8 0.3 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2013) Glyco_hydro_17 PF00332.18 GAM36483.1 - 3.2e-09 36.8 0.2 6.1e-09 35.9 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Aminotran_1_2 PF00155.21 GAM36484.1 - 9.7e-38 130.3 0.0 1.1e-37 130.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAM36484.1 - 0.0023 16.5 0.0 0.0041 15.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF2721 PF11026.8 GAM36485.1 - 0.024 14.5 0.2 0.043 13.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) AgrB PF04647.15 GAM36485.1 - 0.095 12.0 1.7 0.13 11.6 1.7 1.1 1 0 0 1 1 1 0 Accessory gene regulator B DUF1129 PF06570.11 GAM36485.1 - 0.19 11.2 0.6 0.27 10.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2116 PF09889.9 GAM36485.1 - 0.22 11.5 2.0 0.41 10.7 2.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Glucan_synthase PF02364.15 GAM36486.1 - 0 1388.5 0.0 0 1388.0 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 GAM36486.1 - 4e-43 146.8 0.4 1.1e-42 145.4 0.4 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Syndecan PF01034.20 GAM36486.1 - 1.8 8.5 3.6 8.4 6.4 3.6 2.1 1 0 0 1 1 1 0 Syndecan domain SprT-like PF10263.9 GAM36487.1 - 2.3e-34 117.6 0.3 4.1e-34 116.8 0.3 1.4 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 GAM36487.1 - 5.5e-08 32.6 2.9 1e-07 31.7 2.9 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 GAM36487.1 - 0.059 13.5 0.3 0.14 12.3 0.3 1.6 1 0 0 1 1 1 0 Zinc ribbon domain DUF4379 PF14311.6 GAM36487.1 - 0.13 12.6 0.7 0.48 10.8 0.7 2.0 1 0 0 1 1 1 0 Probable Zinc-ribbon domain AIM24 PF01987.17 GAM36488.1 - 4.7e-48 163.7 0.0 6.2e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 ABC_membrane PF00664.23 GAM36489.1 - 6.1e-40 137.6 12.1 7.8e-40 137.3 12.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAM36489.1 - 7.6e-34 117.2 0.0 1.7e-33 116.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GAM36489.1 - 7.9e-07 28.7 0.1 0.0005 19.6 0.0 2.6 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAM36489.1 - 0.00045 20.5 0.0 0.0014 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM36489.1 - 0.00065 20.1 0.0 0.0016 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 GAM36489.1 - 0.0016 18.3 0.0 0.035 13.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 GAM36489.1 - 0.02 14.9 0.0 0.62 10.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAM36489.1 - 0.032 14.0 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 GAM36489.1 - 0.041 14.3 0.0 0.29 11.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 GAM36489.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 GAM36489.1 - 0.07 13.1 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ApbA PF02558.16 GAM36491.1 - 1.1e-30 106.3 0.0 1.4e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 GAM36491.1 - 3.8e-15 56.2 0.0 6.9e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Orthopox_A5L PF06193.11 GAM36491.1 - 0.069 12.6 0.2 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like zf-C3H1 PF10650.9 GAM36492.1 - 3.8e-12 45.7 0.5 5.8e-12 45.1 0.5 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain APG6_N PF17675.1 GAM36492.1 - 0.011 16.3 7.1 0.011 16.3 7.1 4.4 4 1 1 5 5 5 0 Apg6 coiled-coil region HAP1_N PF04849.13 GAM36492.1 - 0.17 11.0 9.4 0.41 9.8 3.5 2.4 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Myosin_head PF00063.21 GAM36493.1 - 4.5e-225 748.9 0.2 2.5e-218 726.7 0.0 2.9 1 1 1 2 2 2 2 Myosin head (motor domain) Myosin_tail_1 PF01576.19 GAM36493.1 - 3.8e-15 54.9 283.5 2e-07 29.3 36.8 8.0 1 1 3 5 5 5 4 Myosin tail Myosin_N PF02736.19 GAM36493.1 - 2.3e-11 43.3 0.0 5.8e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Rootletin PF15035.6 GAM36493.1 - 0.0054 16.8 23.5 0.0054 16.8 23.5 11.2 1 1 6 9 9 9 1 Ciliary rootlet component, centrosome cohesion Isy1 PF06246.12 GAM36494.1 - 6.4e-90 301.2 2.8 7.3e-90 301.0 2.8 1.0 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 GAM36494.1 - 0.056 13.5 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 YolD-like protein RlmM_FDX PF18125.1 GAM36494.1 - 0.17 12.4 0.3 0.37 11.3 0.3 1.5 1 0 0 1 1 1 0 RlmM ferredoxin-like domain MMR_HSR1 PF01926.23 GAM36495.1 - 1.2e-13 51.2 0.0 2.6e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM36495.1 - 2.7e-07 30.7 0.6 7.3e-07 29.2 0.6 1.6 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 GAM36495.1 - 6.2e-06 25.8 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 GAM36495.1 - 0.00022 20.6 0.0 0.00041 19.7 0.0 1.4 1 0 0 1 1 1 1 Septin AIG1 PF04548.16 GAM36495.1 - 0.0016 17.8 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family PduV-EutP PF10662.9 GAM36495.1 - 0.024 14.4 0.0 5.3 6.8 0.0 2.8 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 GAM36495.1 - 0.091 12.2 0.1 1.9 7.9 0.0 2.3 1 1 1 2 2 2 0 ADP-ribosylation factor family HCO3_cotransp PF00955.21 GAM36496.1 - 2.2e-70 237.9 11.7 8e-38 130.5 0.4 2.1 1 1 1 2 2 2 2 HCO3- transporter family PI3Ka PF00613.20 GAM36497.1 - 1.3e-58 197.5 0.1 2.2e-58 196.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 GAM36497.1 - 4.6e-45 154.4 0.0 5e-31 108.4 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 GAM36497.1 - 5.8e-32 110.5 0.0 9.7e-32 109.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 FAA_hydrolase PF01557.18 GAM36497.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family Nse4_C PF08743.10 GAM36498.1 - 1.1e-29 102.5 0.0 3.6e-29 100.9 0.0 1.9 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 GAM36498.1 - 4.4e-14 52.3 0.7 1.1e-13 51.1 0.7 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Acetyltransf_3 PF13302.7 GAM36499.1 - 3.5e-17 63.3 0.0 4.5e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM36499.1 - 0.00035 20.8 0.0 0.00046 20.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4774 PF15999.5 GAM36499.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) DUF4336 PF14234.6 GAM36500.1 - 1.9e-09 37.2 0.0 2.5e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) Sld3_N PF18523.1 GAM36500.1 - 0.021 14.9 0.1 5.6 7.1 0.0 2.1 1 1 1 2 2 2 0 Sld3 N-terminal domain DUF4336 PF14234.6 GAM36502.1 - 0.00034 19.9 0.0 0.00044 19.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) CDC48_N PF02359.18 GAM36502.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain MARVEL PF01284.23 GAM36503.1 - 1.3e-17 64.1 9.2 1.6e-17 63.9 9.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain Papilloma_E5A PF05776.12 GAM36503.1 - 0.13 12.7 0.4 0.13 12.7 0.4 1.6 2 0 0 2 2 2 0 Papillomavirus E5A protein DUF1772 PF08592.11 GAM36504.1 - 0.00027 21.3 0.2 0.00043 20.6 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Sulfatase PF00884.23 GAM36505.1 - 2.7e-69 234.0 0.0 3.3e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 GAM36505.1 - 0.00029 20.7 0.0 0.00067 19.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function Sulfatase_C PF14707.6 GAM36505.1 - 0.0015 19.2 0.0 0.0033 18.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 GAM36505.1 - 0.002 17.8 0.0 0.033 13.8 0.0 2.2 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 GAM36505.1 - 0.017 15.4 1.3 0.091 13.0 0.1 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4976) Sugar_tr PF00083.24 GAM36506.1 - 2.9e-101 339.6 23.5 3.3e-101 339.4 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM36506.1 - 4.5e-23 81.7 29.4 2.9e-13 49.5 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LCCL PF03815.19 GAM36507.1 - 2.4e-21 75.6 0.1 4e-21 74.9 0.1 1.3 1 0 0 1 1 1 1 LCCL domain DUF4191 PF13829.6 GAM36507.1 - 0.091 12.1 3.1 0.19 11.1 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Metallophos PF00149.28 GAM36508.1 - 8.3e-12 46.0 0.0 1.3e-11 45.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM36508.1 - 5.3e-06 26.7 0.1 9.3e-06 25.9 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 GAM36508.1 - 0.0045 16.3 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Tugs PF17840.1 GAM36508.1 - 0.044 14.0 0.0 0.24 11.6 0.0 2.1 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain DUF2509 PF10713.9 GAM36508.1 - 0.19 11.8 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) ThiF PF00899.21 GAM36509.1 - 1.5e-40 139.1 0.0 2.3e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 GAM36509.1 - 0.002 18.3 0.1 0.027 14.7 0.0 2.7 3 0 0 3 3 3 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 GAM36509.1 - 0.0039 17.4 1.7 0.08 13.2 1.7 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 GAM36509.1 - 0.04 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 GAM36509.1 - 0.057 13.9 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 GAM36509.1 - 0.084 12.5 0.2 0.17 11.5 0.2 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF2093 PF09866.9 GAM36509.1 - 0.11 11.9 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) SurA_N_3 PF13624.6 GAM36509.1 - 0.13 12.0 0.1 3.3 7.5 0.0 2.7 2 1 1 3 3 3 0 SurA N-terminal domain Fusion_gly PF00523.18 GAM36509.1 - 0.17 10.1 0.5 0.27 9.5 0.5 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Abhydrolase_1 PF00561.20 GAM36510.1 - 3.4e-46 158.0 0.0 1.6e-45 155.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 GAM36510.1 - 4.2e-05 23.3 0.0 8.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 GAM36510.1 - 0.025 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 GAM36510.1 - 0.082 13.5 1.1 0.26 11.8 1.1 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Gly_transf_sug PF04488.15 GAM36511.1 - 5.9e-14 52.5 0.0 1.1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Pkinase PF00069.25 GAM36512.1 - 5.1e-64 216.2 0.0 6.2e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM36512.1 - 3.9e-33 114.8 0.0 5e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAM36512.1 - 0.0059 15.6 0.0 0.0082 15.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 GAM36512.1 - 0.011 15.4 0.0 0.05 13.2 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 GAM36512.1 - 0.017 14.4 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like ATP-synt_C PF00137.21 GAM36513.1 - 2.7e-28 98.1 33.7 7.8e-17 61.4 12.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.22 GAM36514.1 - 1.1e-80 271.2 0.0 2e-78 263.8 0.0 2.2 2 0 0 2 2 2 2 CNH domain PH_5 PF15405.6 GAM36514.1 - 3e-42 143.9 0.0 7.3e-42 142.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 GAM36514.1 - 3.4e-39 135.0 0.0 6.7e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 GAM36514.1 - 7.6e-15 54.7 0.1 2e-14 53.4 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SRP-alpha_N PF04086.13 GAM36515.1 - 0.15 11.9 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Septin PF00735.18 GAM36516.1 - 1.9e-108 362.0 0.0 3.4e-108 361.2 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAM36516.1 - 3.2e-05 24.0 0.0 7.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM36516.1 - 0.00053 19.6 0.2 0.037 13.5 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 GAM36516.1 - 0.00063 19.8 2.6 0.77 9.8 0.0 3.0 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 GAM36516.1 - 0.0035 17.3 2.7 0.0077 16.2 0.2 2.6 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 GAM36516.1 - 0.043 13.1 0.0 0.088 12.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_33 PF13671.6 GAM36516.1 - 0.051 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAM36516.1 - 0.076 13.3 1.2 0.19 12.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 GAM36516.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase EB1 PF03271.17 GAM36516.1 - 0.12 12.7 2.0 2.8 8.3 1.1 2.6 2 0 0 2 2 2 0 EB1-like C-terminal motif IIGP PF05049.13 GAM36516.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Ribosomal_S17e PF00833.18 GAM36516.1 - 0.5 10.3 3.5 1.1 9.2 3.5 1.5 1 0 0 1 1 1 0 Ribosomal S17 WD40 PF00400.32 GAM36517.1 - 7.2e-05 23.5 2.3 0.61 11.1 0.0 3.3 4 0 0 4 4 4 2 WD domain, G-beta repeat IKI3 PF04762.12 GAM36517.1 - 0.0042 15.2 0.0 0.0055 14.8 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 GAM36517.1 - 0.0078 16.5 0.0 0.6 10.4 0.0 3.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM36517.1 - 0.029 13.3 0.0 0.099 11.6 0.0 1.8 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 GAM36517.1 - 0.16 11.3 0.0 0.45 9.8 0.0 1.5 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal RRM_1 PF00076.22 GAM36518.1 - 2.6e-20 72.0 0.0 7.7e-20 70.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM36518.1 - 1.3e-05 25.2 0.1 4e-05 23.6 0.0 1.9 2 1 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 GAM36518.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 GAM36518.1 - 0.1 12.3 0.2 0.53 10.0 0.2 2.4 1 1 0 1 1 1 0 Ribonuclease B OB domain Hid1 PF12722.7 GAM36518.1 - 4 5.5 7.3 5 5.1 7.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC27 PF09507.10 GAM36518.1 - 6.7 6.0 21.3 8.5 5.7 21.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DLIC PF05783.11 GAM36519.1 - 3.5e-37 128.3 0.7 5e-34 118.0 0.0 3.4 2 1 1 3 3 3 3 Dynein light intermediate chain (DLIC) Urb2 PF10441.9 GAM36519.1 - 0.12 12.3 0.0 0.58 10.1 0.0 1.9 2 0 0 2 2 2 0 Urb2/Npa2 family Y_phosphatase3 PF13350.6 GAM36520.1 - 8.7e-62 209.1 0.0 9.9e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 GAM36520.1 - 0.0039 16.8 0.0 0.012 15.2 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAM36520.1 - 0.0053 16.4 0.0 0.0077 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 GAM36520.1 - 0.037 13.0 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 GAM36520.1 - 0.054 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Spermine_synth PF01564.17 GAM36521.1 - 1e-06 28.3 0.0 2.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 GAM36521.1 - 0.0041 17.0 0.0 0.0085 15.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM36521.1 - 0.063 14.0 0.0 0.2 12.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_30 PF05430.11 GAM36521.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF2052 PF09747.9 GAM36522.1 - 2.8e-22 79.8 22.3 7.6e-12 45.8 1.0 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) ABM PF03992.16 GAM36523.1 - 0.014 15.5 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Pkinase PF00069.25 GAM36524.1 - 3.1e-47 161.2 0.0 4.5e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM36524.1 - 2.1e-25 89.5 0.0 1.2e-24 87.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM36524.1 - 0.00018 20.9 0.1 0.0012 18.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 GAM36524.1 - 0.12 12.0 0.1 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 AMP-binding PF00501.28 GAM36525.1 - 9.3e-93 311.1 0.0 1.1e-92 310.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM36525.1 - 3.3e-21 76.0 0.1 9.1e-21 74.6 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UBA_4 PF14555.6 GAM36526.1 - 5.5e-11 42.1 0.0 1.7e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 UBA-like domain Dynactin_p22 PF07426.11 GAM36527.1 - 1.6e-10 41.1 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Dynactin subunit p22 Ada3 PF10198.9 GAM36527.1 - 0.1 12.7 0.6 0.72 10.0 0.0 2.5 2 1 0 2 2 2 0 Histone acetyltransferases subunit 3 Zn_dep_PLPC PF00882.18 GAM36527.1 - 0.2 11.7 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Zinc dependent phospholipase C SH3_1 PF00018.28 GAM36528.1 - 4.9e-11 42.1 0.1 9.9e-11 41.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAM36528.1 - 3e-07 30.2 0.0 5.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAM36528.1 - 5.1e-06 26.1 0.0 9.4e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 GAM36528.1 - 0.0036 17.3 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain TMEM220 PF15071.6 GAM36528.1 - 0.074 13.8 4.2 0.17 12.7 4.2 1.7 1 1 0 1 1 1 0 Transmembrane family 220, helix DUF4203 PF13886.6 GAM36528.1 - 0.15 11.7 11.7 0.22 11.2 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) DUF2208 PF09973.9 GAM36528.1 - 0.35 10.4 2.6 0.54 9.8 2.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) EMC3_TMCO1 PF01956.16 GAM36528.1 - 0.54 10.0 2.9 2 8.1 0.9 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF2142 PF09913.9 GAM36528.1 - 0.63 8.8 10.1 0.18 10.7 0.7 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2142) DUF1129 PF06570.11 GAM36528.1 - 1.7 8.1 9.9 0.36 10.3 6.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF1290 PF06947.12 GAM36528.1 - 2.5 8.3 7.5 0.13 12.3 2.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1290) PQ-loop PF04193.14 GAM36529.1 - 6e-22 77.2 9.0 6e-20 70.8 0.5 3.3 2 1 1 3 3 3 2 PQ loop repeat ABC2_membrane_5 PF13346.6 GAM36529.1 - 4 6.9 11.7 0.71 9.4 4.7 2.1 1 1 2 3 3 3 0 ABC-2 family transporter protein Response_reg PF00072.24 GAM36530.1 - 9.7e-21 74.0 0.0 1.2e-13 51.2 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain HLH PF00010.26 GAM36531.1 - 1.7e-12 47.1 0.0 3.5e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SR-25 PF10500.9 GAM36531.1 - 0.2 11.2 16.9 0.05 13.2 13.7 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Mito_fiss_reg PF05308.11 GAM36531.1 - 0.24 11.4 12.5 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Hamartin PF04388.12 GAM36531.1 - 1.1 7.8 13.3 1.5 7.4 13.3 1.1 1 0 0 1 1 1 0 Hamartin protein Miga PF10265.9 GAM36531.1 - 1.5 7.7 4.8 2.2 7.2 4.8 1.2 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 GAM36531.1 - 1.6 7.2 10.4 2.4 6.6 10.4 1.2 1 0 0 1 1 1 0 Macoilin family SPATA3 PF15662.5 GAM36531.1 - 2.7 8.6 22.3 0.28 11.8 17.1 1.9 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family Ndc1_Nup PF09531.10 GAM36531.1 - 2.7 6.6 9.0 3.2 6.3 9.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 GAM36531.1 - 5.2 7.0 12.5 4.8 7.1 6.6 2.1 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) Bot1p PF12298.8 GAM36532.1 - 3.4e-56 190.1 2.2 3.4e-56 190.1 2.2 1.8 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Mto2_bdg PF12808.7 GAM36532.1 - 3.7 7.9 12.5 0.73 10.2 0.3 2.7 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region RRM_1 PF00076.22 GAM36533.1 - 2.1e-18 65.9 0.3 3.4e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM36533.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Ribosomal_S16 PF00886.19 GAM36534.1 - 5.8e-25 87.1 0.0 9.8e-25 86.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S16 Isochorismatase PF00857.20 GAM36534.1 - 2.6e-11 44.0 0.0 4.9e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family YjeF_N PF03853.15 GAM36535.1 - 2.7e-34 118.5 0.0 3.5e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PUL PF08324.11 GAM36536.1 - 2.8e-73 246.6 1.1 3.9e-73 246.1 1.1 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 GAM36536.1 - 1.9e-44 150.5 0.1 5.5e-44 149.0 0.2 1.7 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 GAM36536.1 - 5.3e-31 106.2 14.7 6.4e-07 30.0 0.0 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Voldacs PF03517.13 GAM36537.1 - 2.4e-33 115.2 1.2 7.5e-33 113.6 0.0 2.0 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling adh_short_C2 PF13561.6 GAM36539.1 - 5.8e-53 179.8 0.5 1.2e-52 178.8 0.5 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM36539.1 - 6.6e-34 117.1 1.3 3.6e-33 114.7 1.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM36539.1 - 9.3e-09 35.4 1.4 1.2e-07 31.8 0.3 2.2 1 1 1 2 2 2 1 KR domain F420_oxidored PF03807.17 GAM36539.1 - 0.0027 18.2 1.0 0.0048 17.5 1.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 GAM36539.1 - 0.025 14.0 0.1 0.65 9.3 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 GAM36539.1 - 0.078 12.3 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 GAM36539.1 - 0.095 12.1 0.1 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 GAM36539.1 - 0.12 12.2 0.7 0.19 11.6 0.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Opi1 PF08618.10 GAM36541.1 - 1.4e-43 149.8 18.1 8.2e-33 114.3 3.5 3.6 1 1 3 4 4 4 3 Transcription factor Opi1 RdRP PF05183.12 GAM36544.1 - 5.6e-134 448.0 0.0 7.4e-134 447.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Ank_2 PF12796.7 GAM36545.1 - 3.9e-44 149.1 15.4 2.3e-14 53.7 0.2 4.9 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM36545.1 - 2.4e-36 123.6 8.4 1.4e-05 25.5 0.2 8.0 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM36545.1 - 3.5e-27 94.1 11.3 1.2e-05 25.4 0.1 7.3 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 GAM36545.1 - 5.8e-25 86.6 16.9 2.3e-05 24.6 0.1 9.4 10 0 0 10 10 10 6 Ankyrin repeat Ank_3 PF13606.6 GAM36545.1 - 7.6e-25 84.3 9.5 0.043 14.4 0.0 9.2 10 0 0 10 10 10 7 Ankyrin repeat SchA_CurD PF04486.12 GAM36545.1 - 0.13 12.4 0.0 3.4 7.8 0.0 2.7 2 0 0 2 2 2 0 SchA/CurD like domain PEGA PF08308.11 GAM36545.1 - 0.19 11.6 0.0 21 5.1 0.0 2.7 3 0 0 3 3 3 0 PEGA domain SinI PF08671.10 GAM36545.1 - 0.99 9.3 3.4 11 6.0 0.1 2.8 3 0 0 3 3 3 0 Anti-repressor SinI DUF3445 PF11927.8 GAM36546.1 - 3e-76 256.0 0.0 3.9e-76 255.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PRP38 PF03371.15 GAM36547.1 - 2.9e-62 209.6 0.0 3.7e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 PRP38 family Tnp_22_trimer PF17489.2 GAM36547.1 - 0.0022 17.9 0.5 0.0041 17.0 0.5 1.4 1 0 0 1 1 1 1 L1 transposable element trimerization domain HetR_C PF18460.1 GAM36547.1 - 0.053 13.4 0.6 0.11 12.4 0.6 1.5 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain WD40 PF00400.32 GAM36549.1 - 7.5e-17 61.4 0.1 0.16 12.9 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM36549.1 - 7.2e-05 23.0 0.0 28 5.1 0.0 4.7 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nop14 PF04147.12 GAM36549.1 - 6.3 4.9 17.5 9.3 4.3 17.5 1.1 1 0 0 1 1 1 0 Nop14-like family Pyr_redox_2 PF07992.14 GAM36550.1 - 5.9e-37 127.5 0.0 7.7e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM36550.1 - 6.6e-16 58.6 0.1 4.6e-12 46.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM36550.1 - 3.4e-11 43.0 0.0 4.4e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM36550.1 - 5.6e-08 32.7 0.1 0.15 11.6 0.0 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM36550.1 - 5.6e-07 29.7 0.1 0.028 14.4 0.0 4.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 GAM36550.1 - 2.3e-06 27.0 0.2 2.2e-05 23.8 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 GAM36550.1 - 5.5e-06 25.5 0.2 0.39 9.5 0.0 3.1 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_7 PF13241.6 GAM36550.1 - 2.7e-05 24.6 0.0 0.0055 17.1 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 GAM36550.1 - 0.00043 20.5 0.0 0.94 9.8 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 GAM36550.1 - 0.0011 19.2 0.1 0.88 9.8 0.0 2.8 3 0 0 3 3 3 1 TrkA-N domain DUF1188 PF06690.11 GAM36550.1 - 0.0052 16.4 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1188) HI0933_like PF03486.14 GAM36550.1 - 0.0053 15.5 0.0 0.77 8.4 0.0 2.8 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 GAM36550.1 - 0.081 12.0 0.1 1.1 8.3 0.0 2.4 3 0 0 3 3 3 0 FAD binding domain FAD_binding_3 PF01494.19 GAM36550.1 - 0.086 12.1 0.1 7.9 5.6 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 GAM36550.1 - 0.11 11.5 0.0 1.2 8.1 0.0 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 GAM36550.1 - 0.14 12.4 0.0 17 5.7 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain GIDA PF01134.22 GAM36550.1 - 1.1 8.3 4.2 55 2.7 0.1 3.5 2 1 2 4 4 4 0 Glucose inhibited division protein A AAA_12 PF13087.6 GAM36551.1 - 1.1e-35 123.1 0.1 1.9e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAM36551.1 - 3e-22 79.6 0.0 4.8e-21 75.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM36551.1 - 8.7e-10 38.6 0.0 6.1e-07 29.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 GAM36551.1 - 2.5e-09 37.6 0.1 1.2e-07 32.1 0.0 3.3 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 GAM36551.1 - 1.9e-05 24.7 0.0 6.3e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 GAM36551.1 - 0.00083 19.2 0.0 0.23 11.2 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 GAM36551.1 - 0.0011 18.8 0.0 0.0028 17.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 GAM36551.1 - 0.0032 17.0 0.0 0.036 13.6 0.0 2.5 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 GAM36551.1 - 0.011 15.2 0.0 0.029 13.8 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 GAM36551.1 - 0.018 14.3 0.0 0.39 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 GAM36551.1 - 0.068 13.6 0.1 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 GAM36552.1 - 2.1e-55 187.0 0.0 3.5e-32 111.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAM36552.1 - 1.3e-49 169.3 26.1 1.1e-31 110.6 9.8 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 GAM36552.1 - 2e-08 33.9 1.7 0.01 15.3 0.0 4.5 4 1 1 5 5 5 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GAM36552.1 - 5.8e-06 26.4 0.1 0.058 13.5 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM36552.1 - 0.00014 21.8 0.3 0.082 12.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 GAM36552.1 - 0.00015 21.7 7.3 0.026 14.3 0.1 3.8 4 0 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM36552.1 - 0.0005 19.8 0.8 0.5 10.2 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GAM36552.1 - 0.0008 19.7 2.5 8.5 6.6 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_23 PF13476.6 GAM36552.1 - 0.00083 19.9 10.7 0.002 18.7 0.0 3.3 4 0 0 4 4 3 2 AAA domain IstB_IS21 PF01695.17 GAM36552.1 - 0.0013 18.5 0.2 0.25 11.1 0.0 2.9 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 GAM36552.1 - 0.0019 18.6 2.6 0.76 10.1 0.1 3.3 2 2 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 GAM36552.1 - 0.0024 17.0 0.1 0.026 13.6 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.17 GAM36552.1 - 0.0048 17.0 3.5 0.072 13.2 0.4 2.9 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_15 PF13175.6 GAM36552.1 - 0.013 15.2 0.8 1.6 8.4 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 GAM36552.1 - 0.024 15.2 0.1 6.7 7.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 GAM36552.1 - 0.039 13.5 3.0 1.2 8.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.7 GAM36552.1 - 0.049 12.6 0.0 0.53 9.1 0.0 2.5 3 0 0 3 3 3 0 AAA-like domain AAA PF00004.29 GAM36552.1 - 0.078 13.4 0.8 6.1 7.3 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 GAM36552.1 - 0.084 12.1 1.0 5.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 GAM36552.1 - 0.089 12.3 0.2 13 5.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 GAM36552.1 - 0.092 12.3 0.8 0.4 10.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 GAM36552.1 - 0.13 12.0 0.1 17 5.1 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_30 PF13604.6 GAM36552.1 - 0.17 11.6 0.2 5.2 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 GAM36552.1 - 0.17 10.7 1.0 7.8 5.3 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 GAM36552.1 - 0.18 11.9 0.6 20 5.2 0.0 3.0 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.12 GAM36552.1 - 0.33 10.9 1.7 3.1 7.7 0.1 2.6 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 GAM36552.1 - 0.33 10.3 0.9 3.1 7.1 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family UQ_con PF00179.26 GAM36553.1 - 7.9e-38 129.3 0.0 1e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAM36553.1 - 0.031 14.6 0.4 0.057 13.7 0.4 1.6 1 1 0 1 1 1 0 RWD domain SDA1 PF05285.12 GAM36553.1 - 2.5 7.4 13.3 2.9 7.2 13.3 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 GAM36553.1 - 7.1 5.8 16.8 9.1 5.5 16.8 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 GAM36553.1 - 7.8 6.2 13.6 11 5.7 13.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CRAL_TRIO PF00650.20 GAM36554.1 - 9.2e-26 90.5 0.0 1.2e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAM36554.1 - 4.2e-11 42.9 0.0 9.5e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SNase PF00565.17 GAM36555.1 - 1.2e-75 250.9 0.2 3.2e-25 88.7 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 GAM36555.1 - 2e-24 85.9 0.0 4.1e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 GAM36555.1 - 5.1e-06 25.9 0.0 9.5e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 GAM36555.1 - 0.0025 18.3 0.5 0.021 15.3 0.1 2.7 2 0 0 2 2 2 1 Agenet domain Sod_Cu PF00080.20 GAM36556.1 - 1.1e-46 158.5 5.2 1.3e-46 158.3 5.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TAL_FSA PF00923.19 GAM36557.1 - 8.9e-95 317.3 0.0 1e-94 317.1 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Beach PF02138.18 GAM36558.1 - 7.7e-119 396.1 0.0 1.4e-118 395.3 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 GAM36558.1 - 8.7e-12 45.0 1.7 8.9e-12 45.0 0.0 1.9 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 GAM36558.1 - 2.6e-08 34.2 0.0 5.6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4704 PF15787.5 GAM36558.1 - 0.00012 21.4 0.0 0.082 12.1 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4704) WD40 PF00400.32 GAM36558.1 - 0.00019 22.2 7.0 0.16 12.9 0.6 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat AAT PF03417.16 GAM36558.1 - 0.12 12.1 1.7 0.29 10.8 1.7 1.6 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Peptidase_S8 PF00082.22 GAM36559.1 - 1.9e-36 125.9 9.9 3.4e-36 125.0 9.9 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAM36559.1 - 1.8e-21 76.6 0.5 5e-21 75.2 0.2 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 EMC1_C PF07774.13 GAM36560.1 - 1.7e-73 246.8 0.0 3.7e-73 245.7 0.0 1.6 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 GAM36560.1 - 6.6e-36 124.1 11.7 1.7e-31 109.7 4.5 2.9 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.21 GAM36560.1 - 5.1e-06 26.2 6.2 0.15 12.1 0.0 6.1 8 0 0 8 8 8 2 PQQ enzyme repeat PH_8 PF15409.6 GAM36560.1 - 0.099 12.9 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain adh_short PF00106.25 GAM36561.1 - 8.3e-38 129.8 0.0 1.1e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM36561.1 - 6.2e-29 101.2 0.0 8.9e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM36561.1 - 4e-05 23.6 0.0 0.00059 19.8 0.0 2.1 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 GAM36561.1 - 0.11 11.9 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Aa_trans PF01490.18 GAM36562.1 - 6.7e-77 258.9 14.4 6.7e-77 258.9 14.4 2.1 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein DUF1211 PF06736.11 GAM36562.1 - 0.22 12.0 4.8 6.9 7.2 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) Bax1-I PF01027.20 GAM36563.1 - 1.1e-53 182.2 28.5 1.2e-53 182.0 28.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF5504 PF17608.2 GAM36563.1 - 0.0016 18.5 5.4 0.0016 18.5 5.4 2.1 1 1 1 2 2 2 1 Family of unknown function (DUF5504) Spore_YhaL PF14147.6 GAM36563.1 - 2.2 8.0 4.5 1.1 9.0 0.1 2.8 3 0 0 3 3 3 0 Sporulation protein YhaL 7TMR-DISM_7TM PF07695.11 GAM36563.1 - 5.8 6.8 29.5 12 5.7 15.1 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling SPX PF03105.19 GAM36564.1 - 4.6e-83 280.3 6.6 4.6e-83 280.3 6.6 2.1 2 0 0 2 2 2 1 SPX domain EXS PF03124.14 GAM36564.1 - 2e-73 247.6 14.7 2.7e-73 247.2 14.7 1.1 1 0 0 1 1 1 1 EXS family Abhydrolase_1 PF00561.20 GAM36566.1 - 4.4e-25 88.8 0.1 2.1e-19 70.2 0.0 2.4 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 GAM36566.1 - 7.6e-23 79.9 0.1 1.7e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 GAM36566.1 - 0.00012 21.4 0.0 0.018 14.3 0.0 2.5 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 GAM36566.1 - 0.00094 18.9 0.1 0.056 13.1 0.0 2.7 3 0 0 3 3 3 1 Serine hydrolase (FSH1) TauD PF02668.16 GAM36568.1 - 6.5e-38 131.1 0.0 9.7e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 GAM36569.1 - 1.8e-13 50.2 25.2 1.8e-13 50.2 25.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAM36569.1 - 2.3e-08 33.9 4.8 5.1e-08 32.8 4.8 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 PTPlike_phytase PF14566.6 GAM36570.1 - 0.0083 16.3 0.2 0.017 15.3 0.2 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate p450 PF00067.22 GAM36571.1 - 5.8e-68 229.7 0.0 7.7e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pro-kuma_activ PF09286.11 GAM36571.1 - 1.5e-32 112.9 0.1 2.5e-32 112.1 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Histone PF00125.24 GAM36571.1 - 1.5e-19 70.7 0.1 2.8e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Peptidase_S8 PF00082.22 GAM36571.1 - 6.5e-08 32.2 1.5 1.1e-07 31.4 1.5 1.3 1 0 0 1 1 1 1 Subtilase family Flp_C PF05202.12 GAM36571.1 - 0.029 13.9 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Recombinase Flp protein Pet191_N PF10203.9 GAM36572.1 - 1.4e-15 57.3 0.3 1.8e-15 57.0 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 DDOST_48kD PF03345.14 GAM36573.1 - 1.4e-156 521.6 0.0 1.6e-156 521.4 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta NADHdh_A3 PF14987.6 GAM36574.1 - 0.099 13.0 0.1 0.13 12.6 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Mg_chelatase_C PF13335.6 GAM36575.1 - 0.043 14.4 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal IMS PF00817.20 GAM36577.1 - 1.1e-35 122.8 0.0 3.1e-34 118.1 0.0 2.2 1 1 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 GAM36577.1 - 8.3e-15 54.1 2.1 1.7e-14 53.1 2.1 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 GAM36577.1 - 3.1e-13 50.5 0.0 6.8e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 GAM36577.1 - 0.084 13.2 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 IMS family HHH motif GLYCAM-1 PF05242.11 GAM36578.1 - 0.25 11.5 7.9 0.038 14.1 1.1 3.2 3 0 0 3 3 3 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) BTB PF00651.31 GAM36579.1 - 2.4e-11 43.9 0.0 1.2e-10 41.6 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain KxDL PF10241.9 GAM36579.1 - 0.084 13.2 0.3 0.2 12.0 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein WSC PF01822.19 GAM36580.1 - 8.7e-10 38.7 11.9 8.7e-10 38.7 11.9 2.3 2 1 0 2 2 2 1 WSC domain DUF4690 PF15756.5 GAM36580.1 - 0.0064 17.1 9.7 0.0064 17.1 9.7 2.9 2 2 2 4 4 4 1 Small Novel Rich in Cartilage VSP PF03302.13 GAM36580.1 - 0.009 14.9 30.6 0.015 14.2 30.6 1.3 1 1 0 1 1 1 1 Giardia variant-specific surface protein CYYR1 PF10873.8 GAM36580.1 - 0.12 12.9 0.1 0.12 12.9 0.1 3.0 2 1 1 3 3 3 0 Cysteine and tyrosine-rich protein 1 Macoilin PF09726.9 GAM36580.1 - 0.38 9.3 0.7 0.59 8.6 0.7 1.3 1 0 0 1 1 1 0 Macoilin family Podoplanin PF05808.11 GAM36580.1 - 0.56 10.3 24.7 0.18 11.9 21.1 1.8 2 0 0 2 2 2 0 Podoplanin GREB1 PF15782.5 GAM36580.1 - 2.5 5.1 6.5 3 4.9 6.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ank_2 PF12796.7 GAM36581.1 - 5.1e-28 97.5 12.1 3.6e-11 43.5 0.1 5.8 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM36581.1 - 8e-27 93.3 9.0 0.00016 22.2 0.0 8.8 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM36581.1 - 5e-16 58.6 10.0 0.00013 22.2 0.1 8.9 7 3 1 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM36581.1 - 3.8e-15 54.5 12.0 0.4 11.4 0.0 10.8 10 2 0 10 10 10 4 Ankyrin repeat Ank PF00023.30 GAM36581.1 - 2.9e-14 52.8 14.7 0.0095 16.3 0.0 8.9 9 0 0 9 9 9 5 Ankyrin repeat PhyH PF05721.13 GAM36582.1 - 1.8e-28 100.3 0.0 2.5e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AATase PF07247.12 GAM36582.1 - 3.9e-09 35.6 0.0 5.9e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase SMI1_KNR4 PF09346.10 GAM36583.1 - 6.2e-08 33.1 0.0 1.2e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_5 PF14567.6 GAM36583.1 - 0.0029 17.3 0.0 0.0067 16.2 0.0 1.7 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_6 PF14568.6 GAM36583.1 - 0.016 15.6 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall 5_3_exonuc_N PF02739.16 GAM36583.1 - 0.11 12.4 0.1 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain MFS_1 PF07690.16 GAM36585.1 - 4e-09 35.9 6.9 4e-09 35.9 6.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.13 GAM36586.1 - 2.2e-23 83.6 0.0 3.7e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 GAM36587.1 - 1.5e-10 41.7 0.1 1.5e-09 38.5 0.1 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) EspA PF03433.13 GAM36587.1 - 0.17 11.7 0.0 1.4 8.8 0.0 2.0 2 0 0 2 2 2 0 EspA-like secreted protein Zn_clus PF00172.18 GAM36588.1 - 2.2e-11 43.7 8.6 4e-11 42.9 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAM36588.1 - 7.4e-07 28.3 0.0 1e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease_2 PF13520.6 GAM36589.1 - 8.4e-36 123.7 42.4 9.7e-36 123.5 42.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM36589.1 - 7.6e-16 57.8 34.4 1.3e-15 56.9 34.4 1.3 1 1 0 1 1 1 1 Amino acid permease CrgA PF06781.12 GAM36589.1 - 0.12 12.5 0.1 0.12 12.5 0.1 3.3 3 0 0 3 3 3 0 Cell division protein CrgA MFS_1 PF07690.16 GAM36590.1 - 2.4e-33 115.5 68.9 4.9e-29 101.4 50.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_N_4 PF17172.4 GAM36591.1 - 2.4e-20 73.1 0.0 3.9e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 GAM36591.1 - 2.5e-06 27.2 0.0 0.00029 20.6 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 GAM36591.1 - 0.007 16.7 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 GAM36591.1 - 0.12 12.4 0.0 0.56 10.3 0.0 2.1 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain SnoaL_2 PF12680.7 GAM36592.1 - 2.8e-11 43.9 0.2 3.4e-11 43.7 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 GAM36592.1 - 3.8e-05 23.8 0.1 4.2e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 GAM36592.1 - 0.038 14.3 0.0 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Abhydrolase_6 PF12697.7 GAM36593.1 - 1.2e-17 65.3 0.0 1.5e-17 65.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM36593.1 - 3.3e-10 39.6 0.0 5.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM36593.1 - 1e-08 35.2 0.1 5.4e-08 32.8 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 GAM36593.1 - 4.3e-07 30.0 0.1 8.6e-07 29.0 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAM36593.1 - 0.00013 21.8 0.0 0.0014 18.5 0.0 2.3 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 GAM36593.1 - 0.0003 20.7 0.1 0.0005 20.0 0.1 1.3 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.13 GAM36593.1 - 0.0054 16.5 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 GAM36593.1 - 0.012 15.1 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF900 PF05990.12 GAM36593.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 GAM36593.1 - 0.16 11.1 0.0 0.38 9.9 0.0 1.6 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 GAM36593.1 - 0.2 11.8 0.0 0.41 10.7 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain HSF_DNA-bind PF00447.17 GAM36594.1 - 4.6e-31 107.3 1.9 4.6e-31 107.3 1.9 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 GAM36594.1 - 1.8e-23 82.8 0.1 4.1e-23 81.7 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Ets PF00178.22 GAM36594.1 - 0.048 14.1 0.4 0.21 12.1 0.1 2.2 2 0 0 2 2 2 0 Ets-domain W2 PF02020.18 GAM36595.1 - 6.2e-20 71.1 9.1 6.7e-20 71.0 7.0 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 GAM36595.1 - 3.1e-11 42.5 23.9 2.1e-06 27.2 0.4 4.3 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 GAM36595.1 - 3.9e-05 23.3 0.0 8.6e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 GAM36595.1 - 0.00013 21.6 13.0 0.37 10.6 1.0 3.9 1 1 3 4 4 4 4 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 GAM36595.1 - 0.0044 15.2 0.9 0.56 8.3 0.2 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 GAM36595.1 - 0.0091 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 GAM36595.1 - 0.053 12.5 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 L-fucokinase Glyco_hydro_115 PF15979.5 GAM36596.1 - 1.8e-128 428.8 0.0 2.5e-128 428.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 GAM36596.1 - 1.2e-40 139.2 0.0 2e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Glyco_hydro_67N PF03648.14 GAM36596.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus IBR PF01485.21 GAM36597.1 - 2.9e-22 78.6 31.2 4.2e-12 46.1 5.6 3.5 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain UN_NPL4 PF11543.8 GAM36597.1 - 0.011 16.2 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Methyltransf_2 PF00891.18 GAM36597.1 - 0.054 12.8 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Trp_syntA PF00290.20 GAM36597.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Mito_carr PF00153.27 GAM36598.1 - 1.5e-65 217.1 4.9 7.2e-23 80.3 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAM36598.1 - 0.02 14.0 2.4 0.26 10.4 0.1 3.1 2 1 2 4 4 4 0 Gammaproteobacterial serine protease AAA PF00004.29 GAM36599.1 - 1.3e-37 129.2 0.0 2.6e-37 128.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 GAM36599.1 - 9.7e-08 31.9 0.0 1.4e-06 28.2 0.0 2.9 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 GAM36599.1 - 3.6e-07 29.9 0.0 7.7e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 GAM36599.1 - 5e-05 23.6 0.8 0.00068 19.9 0.2 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 GAM36599.1 - 6.8e-05 22.7 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAM36599.1 - 0.00021 21.4 0.0 0.00039 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAM36599.1 - 0.00041 20.8 1.0 0.0036 17.7 0.1 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 GAM36599.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 GAM36599.1 - 0.0031 16.8 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 GAM36599.1 - 0.0041 16.9 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAM36599.1 - 0.0045 16.4 0.1 0.0098 15.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAM36599.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 GAM36599.1 - 0.017 14.3 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 GAM36599.1 - 0.061 12.9 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAM36599.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAM36599.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAM36599.1 - 0.099 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Ntox28 PF15605.6 GAM36599.1 - 0.11 12.8 1.3 0.46 10.8 0.1 2.3 2 0 0 2 2 2 0 Bacterial toxin 28 AAA_7 PF12775.7 GAM36599.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 GAM36599.1 - 0.13 11.9 0.0 0.4 10.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 GAM36599.1 - 0.14 12.3 0.6 0.71 10.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAM36599.1 - 0.15 12.6 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ribosomal_S17 PF00366.20 GAM36600.1 - 6.3e-16 58.2 0.2 1.5e-15 57.1 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S17 Roughex PF06020.11 GAM36600.1 - 0.0082 15.3 6.4 0.017 14.2 6.4 1.5 1 0 0 1 1 1 1 Drosophila roughex protein AvrM-A PF18241.1 GAM36600.1 - 0.17 12.3 0.3 0.17 12.3 0.3 2.2 2 1 0 2 2 2 0 Flax-rust effector AvrM-A Glyco_transf_20 PF00982.21 GAM36601.1 - 4.6e-180 599.3 0.0 5.4e-180 599.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 GAM36601.1 - 0.03 14.0 0.4 0.062 13.0 0.1 1.6 2 0 0 2 2 2 0 Starch synthase catalytic domain LNP1 PF15419.6 GAM36601.1 - 0.086 13.1 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 Aconitase PF00330.20 GAM36602.1 - 3e-151 504.5 0.0 4.1e-151 504.1 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAM36602.1 - 1e-44 152.0 0.0 2.1e-44 151.0 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain BLACT_WH PF17778.1 GAM36602.1 - 7.5e-19 67.5 0.0 2e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 GAM36602.1 - 5.6e-08 33.0 8.9 2.8e-06 27.5 8.9 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM36602.1 - 0.00074 19.1 0.6 0.0018 17.9 0.6 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sdh5 PF03937.16 GAM36602.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase zf-C2H2_jaz PF12171.8 GAM36603.1 - 1.7e-10 40.9 4.2 1.7e-10 40.9 4.2 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-SCNM1 PF15803.5 GAM36603.1 - 0.069 12.8 0.2 0.069 12.8 0.2 1.6 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 TEX13 PF15186.6 GAM36603.1 - 0.075 12.7 0.1 0.075 12.7 0.1 1.6 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Tna_leader PF08053.11 GAM36603.1 - 0.15 12.1 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Tryptophanase operon leader peptide zf-C2H2_4 PF13894.6 GAM36603.1 - 0.22 12.5 1.3 0.22 12.5 1.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAM36603.1 - 0.22 11.9 3.9 0.75 10.2 3.9 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Peptidase_C10 PF01640.17 GAM36604.1 - 0.05 13.9 0.3 0.063 13.6 0.3 1.1 1 0 0 1 1 1 0 Peptidase C10 family Pes-10 PF07149.11 GAM36604.1 - 0.18 10.8 2.4 0.25 10.3 2.4 1.2 1 0 0 1 1 1 0 Pes-10 Terminase_4 PF05119.12 GAM36604.1 - 0.29 11.6 2.1 0.68 10.4 0.6 2.1 1 1 1 2 2 2 0 Phage terminase, small subunit Rad54_N PF08658.10 GAM36605.1 - 2.9e-47 161.2 0.7 7.9e-46 156.5 0.3 2.3 2 0 0 2 2 2 1 Rad54 N terminal SNF2_N PF00176.23 GAM36605.1 - 4.9e-45 153.8 0.0 6.5e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM36605.1 - 3.5e-16 59.5 0.0 9.4e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 GAM36605.1 - 0.0011 18.2 0.0 0.0065 15.7 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 GAM36605.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Vac14_Fig4_bd PF11916.8 GAM36606.1 - 1.9e-81 272.0 8.3 4.6e-81 270.8 8.3 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 GAM36606.1 - 3e-43 146.4 0.0 1.1e-41 141.3 0.0 3.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region DHHC PF01529.20 GAM36606.1 - 4.3e-23 81.9 1.2 4.3e-23 81.9 1.2 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase HEAT_EZ PF13513.6 GAM36606.1 - 3.7e-09 36.9 1.7 0.0037 17.7 0.0 5.1 4 1 1 5 5 4 2 HEAT-like repeat HEAT PF02985.22 GAM36606.1 - 4e-07 29.7 0.6 0.0016 18.5 0.0 5.3 6 0 0 6 6 4 1 HEAT repeat Cnd1 PF12717.7 GAM36606.1 - 0.0002 21.5 0.5 0.23 11.5 0.2 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM36606.1 - 0.00054 20.3 0.1 1.1 9.6 0.0 4.7 4 1 0 4 4 4 1 HEAT repeats DUF3385 PF11865.8 GAM36606.1 - 0.0066 16.4 0.0 1.8 8.4 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Mucin PF01456.17 GAM36606.1 - 0.022 14.7 3.9 0.072 13.1 3.9 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein Arm PF00514.23 GAM36606.1 - 0.065 13.3 0.1 17 5.6 0.0 4.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat COX4_pro_2 PF07835.12 GAM36606.1 - 0.55 10.4 3.4 1.7 8.8 3.4 1.9 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV Glyco_hydro_17 PF00332.18 GAM36609.1 - 5.3e-07 29.5 3.0 5.3e-05 23.0 0.4 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Glyco_hydro_72 PF03198.14 GAM36609.1 - 0.02 14.1 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 Glucanosyltransferase SP_C-Propep PF08999.10 GAM36609.1 - 0.058 13.2 0.0 0.058 13.2 0.0 2.4 2 1 0 2 2 2 0 Surfactant protein C, N terminal propeptide Methyltransf_25 PF13649.6 GAM36610.1 - 4.7e-05 24.0 0.0 7.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM36610.1 - 0.0023 18.5 0.0 0.0039 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM36610.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_4 PF01565.23 GAM36611.1 - 3.3e-18 65.8 0.3 6.3e-18 64.9 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain VHL_C PF17211.3 GAM36611.1 - 0.12 12.3 0.2 1 9.4 0.0 2.2 2 0 0 2 2 2 0 VHL box domain Phage_Arf PF17585.2 GAM36611.1 - 0.29 11.1 1.1 1.4 8.9 0.2 2.4 2 0 0 2 2 2 0 Accessory recombination function protein RTA1 PF04479.13 GAM36612.1 - 1.4e-60 204.4 10.0 1.4e-60 204.4 10.0 1.7 2 0 0 2 2 2 1 RTA1 like protein Glyco_hydro_2_C PF02836.17 GAM36613.1 - 8.4e-51 172.9 0.0 1.1e-50 172.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 GAM36613.1 - 1.7e-46 158.2 1.4 3.4e-45 154.0 0.2 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 GAM36613.1 - 1e-12 48.7 0.1 1.7e-12 47.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Bgal_small_N PF02929.17 GAM36614.1 - 1.5e-65 221.2 0.0 2e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_C PF02836.17 GAM36614.1 - 1.4e-35 122.9 0.0 2.1e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4981 PF16353.5 GAM36614.1 - 3e-14 53.2 0.0 8.4e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Sugar_tr PF00083.24 GAM36615.1 - 5.7e-61 206.8 23.7 1.6e-31 109.6 15.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM36615.1 - 5.3e-23 81.5 24.4 1.4e-18 67.0 16.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM36615.1 - 0.0026 16.2 4.6 0.0031 16.0 0.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Na_Pi_cotrans PF02690.15 GAM36615.1 - 2 8.5 5.8 0.92 9.6 1.9 2.3 2 0 0 2 2 2 0 Na+/Pi-cotransporter DUF3792 PF12670.7 GAM36615.1 - 4 7.6 19.3 0.85 9.8 1.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) Glyco_hydro_1 PF00232.18 GAM36616.1 - 1.9e-142 474.8 0.1 2.3e-142 474.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Fungal_trans PF04082.18 GAM36617.1 - 0.00018 20.6 0.8 0.00052 19.1 0.8 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Tannase PF07519.11 GAM36619.1 - 1.4e-105 354.0 2.4 1.7e-105 353.7 2.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 GAM36619.1 - 0.0034 16.9 0.1 0.0067 15.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family RTA1 PF04479.13 GAM36620.1 - 2.7e-55 187.2 9.6 3.1e-55 187.0 9.6 1.0 1 0 0 1 1 1 1 RTA1 like protein GMC_oxred_N PF00732.19 GAM36621.1 - 4.5e-65 220.0 1.2 5.8e-65 219.6 1.2 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM36621.1 - 6e-32 111.1 0.0 1.9e-31 109.6 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 GAM36621.1 - 0.00014 22.0 0.0 0.0005 20.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM36621.1 - 0.00052 19.3 0.5 0.0031 16.8 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM36621.1 - 0.00062 19.5 0.6 0.0073 15.9 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAM36621.1 - 0.00087 18.4 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 GAM36621.1 - 0.0033 16.7 0.1 0.0064 15.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 GAM36621.1 - 0.0036 16.5 0.3 0.018 14.1 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAM36621.1 - 0.0057 15.4 0.1 0.04 12.6 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 GAM36621.1 - 0.006 17.1 0.4 0.017 15.6 0.2 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GAM36621.1 - 0.012 15.9 0.1 0.028 14.7 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 GAM36621.1 - 0.041 13.1 0.2 1 8.6 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM36621.1 - 0.046 12.6 0.1 0.072 11.9 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 GAM36621.1 - 0.054 13.5 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Aldedh PF00171.22 GAM36622.1 - 2.7e-101 339.4 0.5 3.1e-101 339.2 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_zinc_N PF00107.26 GAM36623.1 - 8.6e-23 80.8 0.2 8.6e-23 80.8 0.2 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM36623.1 - 4.7e-12 45.8 0.6 1.3e-11 44.3 0.6 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 GAM36623.1 - 5.5e-08 32.6 0.1 8.1e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 GAM36623.1 - 9.8e-05 21.7 1.0 0.00017 21.0 1.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 GAM36623.1 - 0.0032 18.5 0.0 0.0079 17.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GCD14 PF08704.10 GAM36623.1 - 0.036 13.7 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit UDPG_MGDP_dh_N PF03721.14 GAM36623.1 - 0.065 12.8 0.3 0.11 12.1 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_31 PF13847.6 GAM36623.1 - 0.079 12.8 0.2 4.9 6.9 0.1 2.3 1 1 1 2 2 2 0 Methyltransferase domain MTS PF05175.14 GAM36623.1 - 0.086 12.4 2.0 0.12 11.9 0.2 1.9 2 0 0 2 2 2 0 Methyltransferase small domain ADH_zinc_N_2 PF13602.6 GAM36624.1 - 2.4e-16 61.0 0.0 3.9e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM36624.1 - 6.4e-10 38.9 0.0 5.2e-07 29.5 0.0 2.9 2 2 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAM36624.1 - 1.1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 GAM36624.1 - 3.2e-06 27.1 0.0 6.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyridoxal_deC PF00282.19 GAM36625.1 - 8.9e-20 70.7 0.0 1.3e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GAM36625.1 - 5.9e-06 25.5 0.0 1e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAM36625.1 - 0.015 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Zn_clus PF00172.18 GAM36626.1 - 8.4e-05 22.6 6.9 0.00018 21.5 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 GAM36627.1 - 3.4e-68 230.4 0.0 3.8e-67 227.0 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAM36627.1 - 3.6e-28 98.7 0.0 6.9e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Trp_halogenase PF04820.14 GAM36627.1 - 0.044 12.6 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 GAM36627.1 - 0.046 12.9 0.1 0.58 9.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM36627.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAM36627.1 - 0.13 10.9 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein SE PF08491.10 GAM36627.1 - 0.16 11.0 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Fungal_trans PF04082.18 GAM36628.1 - 4.6e-15 55.4 0.2 6.7e-15 54.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dioxygenase_C PF00775.21 GAM36629.1 - 4.8e-42 143.4 0.0 7.8e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 GAM36629.1 - 4.2e-32 109.8 0.1 3e-31 107.1 0.0 2.1 2 0 0 2 2 2 1 Catechol dioxygenase N terminus DAGK_cat PF00781.24 GAM36629.1 - 2.4e-26 91.8 0.0 4.2e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Big_1 PF02369.16 GAM36629.1 - 0.083 12.9 0.1 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) ENTH PF01417.20 GAM36629.1 - 0.18 11.8 0.0 0.75 9.9 0.0 1.9 2 0 0 2 2 2 0 ENTH domain adh_short PF00106.25 GAM36630.1 - 3.7e-08 33.1 0.0 8.1e-08 31.9 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM36630.1 - 0.00081 19.0 0.0 0.0023 17.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 GAM36630.1 - 0.0086 16.1 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Amino_oxidase PF01593.24 GAM36631.1 - 5.6e-60 203.9 0.0 6.3e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM36631.1 - 6.2e-12 45.6 0.1 1.2e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM36631.1 - 3e-09 36.9 1.4 5.7e-08 32.7 1.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAM36631.1 - 1.1e-06 28.2 0.9 0.017 14.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM36631.1 - 1e-05 24.9 0.3 0.00088 18.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM36631.1 - 2.6e-05 23.5 0.4 5.1e-05 22.5 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAM36631.1 - 3.6e-05 23.2 0.4 7.2e-05 22.2 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAM36631.1 - 4.7e-05 22.9 0.5 8.2e-05 22.1 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM36631.1 - 8.1e-05 21.5 1.9 0.012 14.4 1.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 GAM36631.1 - 8.9e-05 21.8 0.2 0.00015 21.1 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 GAM36631.1 - 9.1e-05 21.7 1.0 0.096 11.7 0.4 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 GAM36631.1 - 0.00013 22.4 0.6 0.0098 16.4 0.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM36631.1 - 0.00087 19.3 0.3 0.36 10.8 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Rossmann-like PF10727.9 GAM36631.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Rossmann-like domain GIDA PF01134.22 GAM36631.1 - 0.2 10.7 3.0 0.5 9.4 0.6 2.3 2 1 0 2 2 2 0 Glucose inhibited division protein A ADH_zinc_N PF00107.26 GAM36633.1 - 2.2e-10 40.6 0.2 3.9e-10 39.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM36633.1 - 0.00031 20.6 0.1 0.00057 19.7 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.22 GAM36634.1 - 2.3e-54 184.9 0.0 2.7e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PE_PPE_C PF12484.8 GAM36634.1 - 0.11 13.4 0.0 0.22 12.4 0.0 1.4 1 0 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal MFS_1 PF07690.16 GAM36635.1 - 1.9e-23 83.0 41.5 5.6e-21 74.9 28.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily BLACT_WH PF17778.1 GAM36635.1 - 0.11 12.6 0.3 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain SnoaL PF07366.12 GAM36636.1 - 1.9e-28 98.8 0.0 2.2e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 GAM36636.1 - 3.5e-15 56.5 0.1 4.1e-15 56.3 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.16 GAM36637.1 - 1.1e-21 77.2 26.7 1.4e-21 76.9 26.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM36637.1 - 2.4e-07 30.0 7.8 2.4e-07 30.0 7.8 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter Fungal_trans PF04082.18 GAM36639.1 - 2.1e-11 43.3 6.1 5.9e-10 38.6 2.2 2.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM36639.1 - 7.2e-08 32.4 9.6 1.3e-07 31.6 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran_CTD PF16326.5 GAM36639.1 - 1.6 9.1 6.0 2.9 8.2 0.0 3.2 4 0 0 4 4 4 0 ABC transporter C-terminal domain Amidohydro_2 PF04909.14 GAM36640.1 - 1.2e-36 127.0 0.0 1.5e-36 126.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase COesterase PF00135.28 GAM36641.1 - 4.1e-99 332.8 0.0 5e-99 332.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM36641.1 - 0.029 14.2 0.4 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipoprotein_15 PF03640.15 GAM36642.1 - 0.013 15.1 0.1 0.027 14.0 0.1 1.5 1 0 0 1 1 1 0 Secreted repeat of unknown function FAD_binding_3 PF01494.19 GAM36643.1 - 4.2e-08 32.8 1.0 5.3e-06 25.9 0.6 2.7 2 1 0 2 2 2 2 FAD binding domain DNase_NucA_NucB PF14040.6 GAM36644.1 - 0.025 15.0 0.1 0.042 14.2 0.1 1.4 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB SRR1 PF07985.12 GAM36646.1 - 6.1e-18 64.6 0.0 1.1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 SRR1 AKAP28 PF14469.6 GAM36646.1 - 0.14 12.0 0.8 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 28 kDa A-kinase anchor Abhydrolase_6 PF12697.7 GAM36648.1 - 2.3e-16 61.1 3.8 7.1e-15 56.2 3.8 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM36648.1 - 2.6e-15 56.8 0.0 4.2e-15 56.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM36648.1 - 1.8e-06 27.4 0.0 6.6e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 MFS_1 PF07690.16 GAM36650.1 - 0.00033 19.7 0.0 0.00036 19.6 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.25 GAM36651.1 - 7.6e-38 129.9 0.4 2.2e-37 128.4 0.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM36651.1 - 1.5e-27 96.7 0.2 2.5e-27 96.0 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM36651.1 - 2.4e-10 40.6 0.1 3.1e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM36651.1 - 0.0017 17.8 0.1 0.0024 17.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM36651.1 - 0.0022 17.9 0.1 0.0038 17.1 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding eIF-5a PF01287.20 GAM36652.1 - 1.7e-06 28.0 0.0 3.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold PHD PF00628.29 GAM36653.1 - 1.4e-09 37.7 1.8 3.3e-09 36.5 1.8 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAM36653.1 - 0.0089 15.6 2.3 0.015 14.9 2.3 1.4 1 0 0 1 1 1 1 PHD-finger NDUFB11 PF17250.2 GAM36654.1 - 0.12 13.0 5.1 0.62 10.7 0.1 3.5 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase 11 kDa subunit PBP_N PF17093.5 GAM36655.1 - 1.1 9.5 5.2 4.4 7.6 1.9 2.5 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus MARVEL PF01284.23 GAM36655.1 - 1.6 8.8 9.7 5.5 7.0 9.6 2.0 1 1 1 2 2 2 0 Membrane-associating domain DUF1752 PF08550.10 GAM36656.1 - 2.2e-07 30.6 0.4 2.2e-07 30.6 0.4 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) Glyco_hydro_35 PF01301.19 GAM36657.1 - 4.1e-83 279.6 0.0 1e-82 278.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 GAM36657.1 - 2.5e-59 200.1 3.5 4.1e-59 199.4 3.5 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 GAM36657.1 - 2e-54 183.1 5.2 2.3e-31 108.7 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 GAM36657.1 - 1.1e-20 72.9 0.1 3.5e-20 71.3 0.0 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_3_C PF01915.22 GAM36658.1 - 4.4e-41 141.1 0.0 7.1e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAM36658.1 - 2.3e-38 132.3 0.0 3.6e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM36658.1 - 9e-06 25.7 0.0 2.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Gly_transf_sug PF04488.15 GAM36659.1 - 1.9e-11 44.5 0.1 3.9e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 GAM36659.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain PBP1_TM PF14812.6 GAM36660.1 - 0.055 13.8 0.6 0.055 13.8 0.6 4.7 5 1 0 5 5 5 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CPSase_L_D2 PF02786.17 GAM36661.1 - 2.1e-72 243.1 0.0 3.1e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 GAM36661.1 - 2.7e-36 124.0 0.0 5.1e-36 123.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 GAM36661.1 - 3.6e-36 124.1 0.0 7.3e-36 123.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Dala_Dala_lig_C PF07478.13 GAM36661.1 - 2e-10 40.6 0.0 1.7e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAM36661.1 - 4.4e-09 36.1 0.0 8.2e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 GAM36661.1 - 6.6e-05 23.0 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 GAM36661.1 - 0.007 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 GAM36661.1 - 0.016 14.5 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 GAM36661.1 - 0.032 13.8 0.0 0.087 12.4 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.11 GAM36661.1 - 0.035 13.7 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Capsid_VP7 PF17071.5 GAM36661.1 - 0.094 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Outer capsid protein VP7 adh_short_C2 PF13561.6 GAM36662.1 - 9.1e-57 192.3 0.0 1.4e-56 191.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM36662.1 - 1.4e-39 135.6 0.1 2.1e-39 135.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM36662.1 - 5.6e-13 49.2 0.1 8.7e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 GAM36662.1 - 0.0035 16.8 0.1 0.51 9.7 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAM36662.1 - 0.0098 15.4 0.1 0.036 13.5 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TraC PF07820.12 GAM36662.1 - 0.23 11.8 1.8 2.4 8.5 1.0 2.2 2 0 0 2 2 2 0 TraC-like protein DUF3883 PF13020.6 GAM36663.1 - 0.0015 18.5 0.0 0.0062 16.5 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3883) DUF3806 PF12713.7 GAM36663.1 - 0.0044 16.7 0.0 0.0088 15.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3806) MPDZ_u10 PF16667.5 GAM36663.1 - 0.018 15.9 1.0 0.044 14.7 1.0 1.6 1 0 0 1 1 1 0 Unstructured region 10 on multiple PDZ protein THOC7 PF05615.13 GAM36664.1 - 0.038 14.3 12.0 0.088 13.1 12.0 1.6 1 0 0 1 1 1 0 Tho complex subunit 7 Arena_ncap_C PF17290.2 GAM36664.1 - 0.061 12.7 0.2 0.18 11.1 0.2 1.7 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain APG6_N PF17675.1 GAM36664.1 - 0.16 12.5 15.7 0.4 11.2 15.7 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region ALMT PF11744.8 GAM36664.1 - 0.28 10.0 7.3 0.17 10.7 5.6 1.4 1 1 0 1 1 1 0 Aluminium activated malate transporter DUF2205 PF10224.9 GAM36664.1 - 0.32 11.0 9.8 1 9.4 9.1 2.3 1 1 0 1 1 1 0 Short coiled-coil protein Jnk-SapK_ap_N PF09744.9 GAM36664.1 - 0.35 11.1 16.2 0.72 10.1 16.2 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 GAM36664.1 - 0.5 10.4 24.1 0.15 12.2 9.8 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 GAM36664.1 - 0.67 8.5 7.1 0.97 8.0 7.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 GAM36664.1 - 0.95 9.0 8.9 1.7 8.1 8.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.9 GAM36664.1 - 1 9.4 19.5 77 3.3 19.5 2.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LMBR1 PF04791.16 GAM36664.1 - 1.2 8.0 8.5 1.6 7.5 8.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RasGAP_C PF03836.15 GAM36664.1 - 2 8.5 13.6 5.3 7.2 6.8 2.4 1 1 1 2 2 2 0 RasGAP C-terminus Sec16 PF12932.7 GAM36664.1 - 2.3 8.8 4.9 4.5 7.9 4.6 1.6 1 1 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region IFT57 PF10498.9 GAM36664.1 - 3 6.7 16.3 3.5 6.5 15.7 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Atg14 PF10186.9 GAM36664.1 - 4.3 6.3 12.1 6.8 5.7 12.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 GAM36664.1 - 8.2 7.1 14.2 2.2 9.0 5.9 2.5 1 1 1 2 2 2 0 Initiation control protein YabA HSP70 PF00012.20 GAM36665.1 - 8.9e-12 44.0 0.0 1.7e-11 43.1 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAM36665.1 - 3.9e-06 25.9 1.0 0.015 14.1 0.1 2.4 2 0 0 2 2 2 2 MreB/Mbl protein Acyl-CoA_dh_1 PF00441.24 GAM36666.1 - 8.1e-40 136.5 0.5 1.3e-39 135.8 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAM36666.1 - 1.3e-31 109.6 0.1 2.4e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAM36666.1 - 3.8e-27 94.3 0.1 7.6e-27 93.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAM36666.1 - 2.2e-14 53.8 0.0 3.7e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 GAM36666.1 - 0.0008 19.1 0.0 0.0029 17.3 0.0 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.22 GAM36667.1 - 9.5e-138 459.9 0.1 1.1e-137 459.6 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Ras PF00071.22 GAM36668.1 - 2.8e-52 176.6 0.0 3.4e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM36668.1 - 6.2e-19 68.4 0.0 9.4e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM36668.1 - 5.7e-10 38.9 0.0 6.7e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM36668.1 - 2.5e-05 23.9 0.1 0.00025 20.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM36668.1 - 0.00011 22.3 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM36668.1 - 0.0016 18.4 0.2 2.1 8.2 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 GAM36668.1 - 0.042 14.1 0.5 0.53 10.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain Septin PF00735.18 GAM36668.1 - 0.088 12.1 0.0 1.8 7.8 0.0 2.2 1 1 0 2 2 2 0 Septin Redoxin PF08534.10 GAM36669.1 - 4e-28 98.0 0.1 4.8e-28 97.7 0.1 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAM36669.1 - 5.3e-07 29.6 0.0 6.9e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family BolA PF01722.18 GAM36670.1 - 1.5e-18 66.8 0.0 3.4e-18 65.7 0.0 1.5 1 1 0 1 1 1 1 BolA-like protein NIF3 PF01784.18 GAM36671.1 - 5.4e-56 190.0 0.0 6.7e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) COG6 PF06419.11 GAM36672.1 - 9.4e-208 691.4 0.1 1.1e-207 691.2 0.1 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.11 GAM36672.1 - 0.00049 20.2 2.0 0.0034 17.5 0.3 3.0 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF4054 PF13262.6 GAM36672.1 - 0.017 15.1 0.2 0.1 12.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) DUF948 PF06103.11 GAM36672.1 - 0.038 14.2 0.8 0.15 12.3 0.3 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Forkhead PF00250.18 GAM36672.1 - 0.12 12.7 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 Forkhead domain GAS PF13851.6 GAM36673.1 - 0.0051 16.2 0.4 0.0051 16.2 0.4 2.4 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding SEO_N PF14576.6 GAM36673.1 - 0.018 14.2 0.2 0.029 13.6 0.2 1.3 1 0 0 1 1 1 0 Sieve element occlusion N-terminus CENP-F_leu_zip PF10473.9 GAM36673.1 - 0.023 14.7 14.3 0.12 12.4 0.6 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Takusan PF04822.13 GAM36673.1 - 0.026 14.4 0.5 0.026 14.4 0.5 2.9 4 0 0 4 4 4 0 Takusan GIT_CC PF16559.5 GAM36673.1 - 0.16 11.8 4.4 2.1 8.3 0.5 3.1 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor APG6_N PF17675.1 GAM36673.1 - 0.31 11.6 21.0 0.29 11.7 0.8 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region FliD_N PF02465.18 GAM36673.1 - 0.46 11.2 2.9 1.9 9.2 0.0 2.9 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Fib_alpha PF08702.10 GAM36673.1 - 0.57 10.4 6.1 9.5 6.4 0.8 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 GAM36673.1 - 0.88 10.1 6.6 10 6.7 0.1 3.7 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Nsp1_C PF05064.13 GAM36673.1 - 4.8 7.0 9.0 17 5.3 3.3 3.1 1 1 2 3 3 3 0 Nsp1-like C-terminal region FapA PF03961.13 GAM36673.1 - 5.7 5.4 9.1 3.5 6.1 0.4 2.4 1 1 2 3 3 3 0 Flagellar Assembly Protein A MCU PF04678.13 GAM36673.1 - 6.7 6.8 6.9 34 4.5 6.8 2.2 1 1 0 1 1 1 0 Mitochondrial calcium uniporter HSP9_HSP12 PF04119.12 GAM36674.1 - 5.4e-29 100.4 8.2 1.8e-28 98.7 7.8 1.8 2 0 0 2 2 2 1 Heat shock protein 9/12 YtxH PF12732.7 GAM36674.1 - 0.063 13.8 1.8 0.21 12.1 0.9 2.1 1 1 1 2 2 2 0 YtxH-like protein Tombus_movement PF05318.12 GAM36674.1 - 0.16 12.8 3.8 0.37 11.7 3.5 1.8 1 1 0 1 1 1 0 Tombusvirus movement protein Flavodoxin_2 PF02525.17 GAM36675.1 - 1.1e-57 194.9 0.0 1.3e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 GAM36675.1 - 1.1e-13 51.2 0.0 2.2e-13 50.2 0.0 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Glyco_hydro_12 PF01670.16 GAM36676.1 - 1.4e-33 116.7 9.2 2.7e-33 115.8 9.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_hydro_79C PF16862.5 GAM36676.1 - 1.8e-23 83.4 0.1 5.4e-23 81.8 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain NYN PF01936.18 GAM36677.1 - 0.00014 22.4 0.0 0.00073 20.0 0.0 2.4 1 1 0 1 1 1 1 NYN domain DSBA PF01323.20 GAM36679.1 - 3.3e-30 105.3 0.0 3.9e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain MFS_1 PF07690.16 GAM36680.1 - 6.5e-46 156.9 44.2 9.7e-46 156.3 41.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM36680.1 - 7.8e-14 51.0 25.7 1e-13 50.6 25.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM36680.1 - 1.5e-09 37.3 35.4 1.2e-07 31.0 13.9 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 GAM36680.1 - 0.18 10.1 15.7 0.71 8.1 15.7 2.0 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DPM3 PF08285.11 GAM36680.1 - 0.99 9.6 7.7 0.13 12.5 0.8 3.1 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3533 PF12051.8 GAM36682.1 - 7.3e-81 272.0 19.0 9.4e-81 271.6 19.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) TPR_10 PF13374.6 GAM36683.1 - 3.6e-158 509.9 12.1 7.8e-13 47.8 0.0 14.7 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_12 PF13424.6 GAM36683.1 - 1.3e-132 432.3 29.8 7.2e-16 58.2 0.0 13.2 2 2 12 14 14 14 14 Tetratricopeptide repeat TPR_7 PF13176.6 GAM36683.1 - 4.3e-35 117.2 14.8 0.013 15.5 0.0 12.2 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_4 PF07721.14 GAM36683.1 - 1.1e-31 106.2 0.0 0.088 13.5 0.0 13.3 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAM36683.1 - 2.7e-24 83.9 15.2 0.0015 18.3 0.0 12.3 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAM36683.1 - 1.3e-22 78.0 16.7 0.035 14.2 0.0 12.5 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAM36683.1 - 7.4e-20 69.8 10.8 1.2 9.7 0.0 11.4 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM36683.1 - 1.9e-19 70.3 14.3 0.00057 19.4 0.0 6.0 1 1 5 6 6 6 6 MalT-like TPR region TPR_8 PF13181.6 GAM36683.1 - 1.1e-18 65.8 20.1 0.1 12.8 0.0 11.8 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAM36683.1 - 1.5e-15 57.5 12.3 0.23 12.0 0.2 10.6 4 4 8 12 12 12 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM36683.1 - 4.2e-14 52.9 9.5 1.6 9.4 0.0 11.1 10 2 0 11 11 10 2 Tetratricopeptide repeat TPR_3 PF07720.12 GAM36683.1 - 1.3e-06 28.2 0.0 3.3 7.8 0.0 7.7 9 0 0 9 9 9 1 Tetratricopeptide repeat PPR PF01535.20 GAM36683.1 - 3.1e-05 23.9 15.2 8.8 6.8 0.0 10.6 13 0 0 13 13 12 0 PPR repeat TPR_14 PF13428.6 GAM36683.1 - 0.00046 20.8 22.4 11 7.1 0.0 11.0 12 1 1 13 13 11 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM36683.1 - 0.0018 18.4 0.2 27 5.1 0.0 6.0 4 2 3 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 Oberon_cc PF16312.5 GAM36683.1 - 0.005 16.8 3.3 2.3 8.1 0.1 4.5 4 0 0 4 4 4 1 Coiled-coil region of Oberon DUF1924 PF09086.11 GAM36683.1 - 0.014 15.8 0.1 5.3 7.5 0.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1924) RST PF12174.8 GAM36683.1 - 0.016 15.1 0.0 0.99 9.4 0.0 2.7 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain YqaH PF17448.2 GAM36683.1 - 0.021 15.1 0.4 60 4.0 0.0 4.7 5 0 0 5 5 5 0 Uncharacterized YqaH-like TPR_11 PF13414.6 GAM36683.1 - 0.027 14.2 2.9 6 6.6 0.0 5.6 6 0 0 6 6 5 0 TPR repeat DUF4747 PF15931.5 GAM36683.1 - 0.06 13.0 0.7 16 5.0 0.0 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4747) DUF2518 PF10726.9 GAM36683.1 - 0.062 13.0 0.2 6.2 6.5 0.0 3.8 1 1 2 3 3 3 0 Protein of function (DUF2518) PPR_1 PF12854.7 GAM36683.1 - 0.092 12.5 11.9 9.9 6.0 0.0 7.7 9 0 0 9 9 8 0 PPR repeat ArdA PF07275.11 GAM36683.1 - 0.11 13.1 4.8 13 6.3 1.0 4.0 2 2 0 3 3 3 0 Antirestriction protein (ArdA) Gln_amidase PF15644.6 GAM36683.1 - 0.21 12.7 0.7 26 5.9 0.0 4.2 4 1 1 5 5 4 0 Papain fold toxin 1, glutamine deamidase DUF1897 PF09005.10 GAM36683.1 - 0.22 11.0 4.7 13 5.3 0.0 4.9 5 0 0 5 5 5 0 Domain of unknown function (DUF1897) TPR_6 PF13174.6 GAM36683.1 - 0.79 10.5 16.9 74 4.3 0.0 8.5 8 0 0 8 8 7 0 Tetratricopeptide repeat Osmo_CC PF08946.10 GAM36683.1 - 0.81 10.0 5.8 1.4e+02 2.9 0.0 5.6 7 0 0 7 7 5 0 Osmosensory transporter coiled coil RPN6_C_helix PF18503.1 GAM36683.1 - 1.2 8.9 4.9 63 3.4 0.0 4.7 5 0 0 5 5 4 0 26S proteasome subunit RPN6 C-terminal helix domain RPN6_N PF18055.1 GAM36683.1 - 1.8 9.0 7.8 20 5.6 0.0 5.1 3 3 4 8 8 8 0 26S proteasome regulatory subunit RPN6 N-terminal domain PPR_2 PF13041.6 GAM36683.1 - 1.8 8.8 4.2 85 3.5 0.0 4.4 7 0 0 7 7 3 0 PPR repeat family Peptidase_S8 PF00082.22 GAM36684.1 - 4e-17 62.4 0.1 1.8e-16 60.3 0.1 1.9 1 1 0 1 1 1 1 Subtilase family DUF5607 PF18355.1 GAM36684.1 - 0.034 14.6 0.7 0.073 13.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5607) DUF2884 PF11101.8 GAM36684.1 - 0.1 12.1 1.3 0.2 11.1 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) HEM4 PF02602.15 GAM36686.1 - 1.5e-37 129.2 0.0 2.6e-37 128.4 0.0 1.4 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pro_CA PF00484.19 GAM36687.1 - 8.7e-11 42.4 0.1 1e-09 38.9 0.1 2.2 1 1 0 1 1 1 1 Carbonic anhydrase DUF1907 PF08925.11 GAM36688.1 - 2.2e-104 348.9 0.0 2.9e-104 348.5 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) Pkinase PF00069.25 GAM36688.1 - 1.1e-66 224.9 0.0 1.6e-66 224.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM36688.1 - 1.9e-31 109.3 0.0 3.6e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAM36688.1 - 0.00071 19.0 0.2 0.0016 17.8 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAM36688.1 - 0.015 14.3 0.1 0.026 13.5 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 GAM36688.1 - 0.031 13.6 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 GAM36688.1 - 0.089 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sec23_trunk PF04811.15 GAM36689.1 - 8.8e-70 235.0 0.0 1.6e-69 234.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAM36689.1 - 8.3e-23 80.2 0.0 2.8e-22 78.5 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAM36689.1 - 3.4e-17 63.0 0.0 8.1e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAM36689.1 - 8.6e-17 60.9 5.0 1.5e-16 60.1 5.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAM36689.1 - 2.1e-09 37.1 0.0 5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 GAM36689.1 - 0.028 13.8 0.1 0.06 12.8 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Kinesin PF00225.23 GAM36690.1 - 5.9e-83 278.5 0.1 5.9e-83 278.5 0.1 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAM36690.1 - 5.8e-22 78.2 0.0 1.2e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 GAM36690.1 - 2.7e-05 23.8 0.1 0.13 12.2 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.6 GAM36690.1 - 0.0001 22.9 0.1 0.73 10.5 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH_3 PF12836.7 GAM36690.1 - 0.089 13.1 0.1 6.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif Mog1 PF04603.12 GAM36691.1 - 1.1e-28 100.3 0.0 1.5e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein NmrA PF05368.13 GAM36692.1 - 9.6e-15 54.8 0.0 1.6e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAM36692.1 - 7.8e-14 51.7 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM36692.1 - 6.4e-13 49.0 0.0 1.2e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Methyltransf_23 PF13489.6 GAM36692.1 - 1.2e-12 48.0 0.0 2.5e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 GAM36692.1 - 3.4e-11 42.7 0.0 6e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.6 GAM36692.1 - 7.5e-11 42.6 0.0 2.9e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM36692.1 - 7.5e-11 42.1 0.0 1.3e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM36692.1 - 6.2e-10 39.6 0.0 1.6e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM36692.1 - 1.3e-08 35.5 0.0 4e-08 33.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM36692.1 - 2.7e-08 33.4 0.0 2.3e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family GDP_Man_Dehyd PF16363.5 GAM36692.1 - 2.6e-07 30.3 0.2 8.3e-07 28.7 0.1 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAM36692.1 - 1.7e-06 27.4 0.0 1.9e-05 23.9 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 GAM36692.1 - 0.00077 19.0 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 GAM36692.1 - 0.0012 18.1 0.1 0.057 12.6 0.1 2.8 2 1 1 3 3 3 1 Male sterility protein Methyltransf_32 PF13679.6 GAM36692.1 - 0.019 15.0 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF4838 PF16126.5 GAM36692.1 - 0.047 13.1 0.1 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4838) KR PF08659.10 GAM36692.1 - 0.063 13.2 0.0 2 8.3 0.0 2.8 2 1 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 GAM36692.1 - 0.18 10.9 0.0 0.39 9.8 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 GAM36692.1 - 0.19 11.2 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PCI PF01399.27 GAM36693.1 - 6.4e-09 36.3 0.0 1.5e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 GAM36693.1 - 6e-05 22.5 0.9 0.00012 21.5 0.9 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix IstB_IS21_ATP PF08483.11 GAM36693.1 - 0.049 13.5 0.0 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal Gaa1 PF04114.14 GAM36694.1 - 3.2e-185 616.9 5.5 3.8e-185 616.6 5.5 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.22 GAM36695.1 - 1.3e-17 64.2 10.4 1.3e-17 64.2 10.4 1.5 2 0 0 2 2 2 1 Rhomboid family Ytp1 PF10355.9 GAM36696.1 - 1.1e-114 382.4 8.9 1.9e-114 381.6 8.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 GAM36696.1 - 1.5e-28 98.6 5.9 1.5e-28 98.6 5.9 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Trp_oprn_chp PF09534.10 GAM36696.1 - 0.42 10.4 2.8 1.5 8.6 0.0 2.9 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) UCH PF00443.29 GAM36697.1 - 8e-39 133.7 0.0 1.3e-38 133.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM36697.1 - 6.7e-11 42.3 9.9 1.3e-06 28.3 0.0 3.5 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF4589 PF15252.6 GAM36697.1 - 0.12 12.4 2.5 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) LPP PF04728.13 GAM36697.1 - 0.15 12.5 0.6 0.5 10.8 0.1 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper zf-C2H2_12 PF18658.1 GAM36697.1 - 0.16 11.5 0.2 0.82 9.3 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger C2H2-type DASH_Dam1 PF08653.10 GAM36698.1 - 1.7e-29 101.4 2.5 2.4e-29 100.9 2.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.20 GAM36699.1 - 1.2e-44 151.9 0.0 3.2e-44 150.5 0.1 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAM36699.1 - 1.2e-14 54.2 0.4 1.2e-14 54.2 0.4 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAM36699.1 - 1.9e-07 31.3 0.0 3.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Glyco_hydro_36 PF17167.4 GAM36699.1 - 0.082 11.6 1.2 1.2 7.7 0.4 2.2 2 1 0 2 2 2 0 Glycosyl hydrolase 36 superfamily, catalytic domain Retrotrans_gag PF03732.17 GAM36699.1 - 0.092 13.0 0.5 0.33 11.3 0.5 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein SAE2 PF08573.10 GAM36699.1 - 0.33 12.1 3.0 0.43 11.7 1.1 2.1 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus HIT PF01230.23 GAM36700.1 - 7.3e-24 84.4 0.1 9.9e-24 83.9 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GAM36700.1 - 2.3e-13 50.6 0.0 3.3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 GAM36700.1 - 0.00022 21.1 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 S10_plectin PF03501.15 GAM36704.1 - 1.8e-41 140.1 0.1 2.3e-41 139.8 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Sde2_N_Ubi PF13019.6 GAM36705.1 - 4.1e-71 238.1 0.6 6.5e-71 237.5 0.6 1.3 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain MMR_HSR1 PF01926.23 GAM36706.1 - 5.6e-05 23.2 0.1 0.048 13.7 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase ATPase-cat_bd PF12156.8 GAM36706.1 - 0.036 14.8 0.0 0.082 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase PLU-1 PF08429.11 GAM36706.1 - 0.041 13.1 0.5 0.082 12.1 0.5 1.5 1 1 0 1 1 1 0 PLU-1-like protein RsgA_GTPase PF03193.16 GAM36706.1 - 0.044 13.7 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 RsgA GTPase Septin PF00735.18 GAM36706.1 - 0.11 11.7 1.2 0.89 8.8 0.0 2.6 3 0 0 3 3 3 0 Septin Dynamin_N PF00350.23 GAM36706.1 - 0.14 12.2 1.0 6.7 6.7 0.2 2.9 1 1 0 2 2 2 0 Dynamin family ENTH PF01417.20 GAM36707.1 - 1e-46 158.0 0.0 1.6e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 GAM36707.1 - 0.00017 20.7 0.0 0.00025 20.1 0.0 1.2 1 0 0 1 1 1 1 ANTH domain UIM PF02809.20 GAM36707.1 - 0.00019 21.1 5.1 0.0013 18.5 1.0 2.7 2 0 0 2 2 2 1 Ubiquitin interaction motif DUF1720 PF08226.11 GAM36707.1 - 0.0046 17.3 26.8 0.0046 17.3 26.8 4.4 2 2 0 3 3 3 1 Domain of unknown function (DUF1720) DUF4264 PF14084.6 GAM36707.1 - 0.0056 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) TMEM219 PF14940.6 GAM36707.1 - 0.23 11.0 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane 219 tRNA-synt_1 PF00133.22 GAM36708.1 - 2.9e-37 128.2 0.0 6.9e-27 93.9 0.0 3.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAM36708.1 - 5.6e-16 58.9 0.1 1.2e-15 57.8 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAM36708.1 - 1.1e-14 54.1 0.0 1.4e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 GAM36708.1 - 2.1e-07 30.6 0.0 5.9e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 GAM36708.1 - 0.094 11.6 0.0 0.26 10.1 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (K) L51_S25_CI-B8 PF05047.16 GAM36709.1 - 4e-08 33.1 0.0 6.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain BRCT_3 PF18428.1 GAM36709.1 - 0.015 15.3 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF1751 PF08551.10 GAM36710.1 - 9.2e-26 90.3 2.7 9.9e-22 77.4 1.9 2.6 2 0 0 2 2 2 2 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 GAM36710.1 - 0.00021 21.3 6.1 0.0013 18.8 6.1 2.0 1 1 0 1 1 1 1 Rhomboid family eIF2A PF08662.11 GAM36711.1 - 6e-12 45.8 0.4 2.7e-08 34.0 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 GAM36711.1 - 2.3e-08 34.2 2.2 0.0012 19.0 0.0 5.2 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAM36711.1 - 4.4e-05 24.1 11.6 0.45 11.5 0.0 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat IKI3 PF04762.12 GAM36711.1 - 0.064 11.2 1.1 0.68 7.8 0.1 2.1 1 1 1 2 2 2 0 IKI3 family PD40 PF07676.12 GAM36711.1 - 0.067 13.1 0.8 1.9 8.5 0.1 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 GAM36711.1 - 0.12 11.4 0.9 11 4.8 0.1 2.6 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MobC PF05713.11 GAM36712.1 - 0.042 14.3 0.7 15 6.1 0.0 3.1 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) ATG16 PF08614.11 GAM36712.1 - 0.049 13.9 8.4 0.038 14.2 3.0 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) HAUS2 PF15003.6 GAM36712.1 - 0.13 12.0 2.1 0.18 11.5 0.1 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 CCDC-167 PF15188.6 GAM36712.1 - 0.17 12.3 1.6 0.42 11.0 1.6 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF1664 PF07889.12 GAM36712.1 - 0.19 11.8 0.6 3 7.9 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Chorismate_bind PF00425.18 GAM36713.1 - 2.9e-90 302.3 0.0 4.3e-90 301.8 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 GAM36713.1 - 3.6e-28 98.6 0.0 5.5e-24 85.0 0.0 3.1 3 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region Phage_holin_3_1 PF05106.12 GAM36713.1 - 0.14 12.6 0.0 4.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) DAO PF01266.24 GAM36714.1 - 2.2e-28 99.8 0.0 2.7e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAM36714.1 - 1.4e-06 27.8 0.0 2.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 GAM36714.1 - 2e-05 24.7 0.0 4.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAM36714.1 - 0.0011 19.0 0.1 0.002 18.1 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAM36714.1 - 0.0029 16.9 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM36714.1 - 0.013 14.6 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAM36714.1 - 0.019 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM36714.1 - 0.03 13.4 0.1 0.047 12.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 GAM36714.1 - 0.053 12.8 0.0 0.085 12.1 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase MCRA PF06100.11 GAM36714.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 MCRA family Semialdhyde_dh PF01118.24 GAM36714.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CLASP_N PF12348.8 GAM36715.1 - 5.8e-08 32.6 0.1 6.7e-06 25.8 0.1 2.9 2 1 0 2 2 2 1 CLASP N terminal HEAT_2 PF13646.6 GAM36715.1 - 7.6e-06 26.2 1.8 0.016 15.6 0.0 4.5 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 GAM36715.1 - 0.00025 21.0 2.2 3.5 8.1 0.5 4.4 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.20 GAM36715.1 - 0.0011 17.7 0.5 0.0065 15.1 0.5 2.2 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAM36715.1 - 0.0014 18.7 0.4 1.9 8.5 0.0 2.7 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 TAN PF11640.8 GAM36715.1 - 0.0016 18.6 0.1 0.0016 18.6 0.1 2.5 2 1 0 2 2 2 1 Telomere-length maintenance and DNA damage repair MMS19_N PF14500.6 GAM36715.1 - 0.052 13.1 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF3584 PF12128.8 GAM36715.1 - 0.16 9.4 9.6 0.31 8.5 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Proteasom_PSMB PF10508.9 GAM36715.1 - 0.6 8.5 3.0 0.32 9.5 0.0 2.0 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Spc7 PF08317.11 GAM36715.1 - 1.8 7.3 10.9 4.5 6.1 10.9 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein G-gamma PF00631.22 GAM36715.1 - 2.2 8.4 6.1 0.29 11.2 0.4 2.5 2 0 0 2 2 2 0 GGL domain adh_short PF00106.25 GAM36716.1 - 1.9e-20 73.1 0.2 9.9e-20 70.8 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM36716.1 - 6.9e-16 58.5 0.2 4.2e-15 56.0 0.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM36716.1 - 3e-12 46.8 0.0 4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM36716.1 - 0.00099 18.6 0.1 0.0093 15.4 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAM36716.1 - 0.011 16.0 0.0 0.029 14.6 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 GAM36716.1 - 0.011 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ets PF00178.22 GAM36716.1 - 0.066 13.7 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 Ets-domain Ribosomal_L7Ae PF01248.26 GAM36717.1 - 1.6e-22 79.0 0.5 2.5e-22 78.4 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 GAM36717.1 - 0.11 11.5 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Clat_adaptor_s PF01217.20 GAM36718.1 - 3.8e-43 146.8 0.0 1.1e-42 145.3 0.0 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MMR_HSR1 PF01926.23 GAM36719.1 - 5.3e-18 65.2 0.2 1.3e-17 63.9 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAM36719.1 - 7.3e-06 26.1 0.0 0.0025 17.9 0.0 2.5 2 0 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 GAM36719.1 - 2.2e-05 24.4 1.0 0.0011 18.9 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 GAM36719.1 - 3.8e-05 23.3 0.0 6.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAM36719.1 - 5e-05 22.9 0.1 0.003 17.1 0.1 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 GAM36719.1 - 0.0043 16.4 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 GAM36719.1 - 0.035 14.3 0.3 0.12 12.6 0.1 2.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 GAM36719.1 - 0.041 14.4 0.1 0.1 13.1 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 GAM36719.1 - 0.045 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mesothelin PF06060.12 GAM36719.1 - 0.055 11.6 0.2 0.085 11.0 0.2 1.2 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) SRPRB PF09439.10 GAM36719.1 - 0.083 12.3 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit IIGP PF05049.13 GAM36719.1 - 0.15 11.0 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Sec63 PF02889.16 GAM36720.1 - 5.8e-32 110.9 0.1 9.6e-32 110.1 0.1 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 GAM36720.1 - 6.4e-25 87.9 0.0 1.9e-24 86.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 GAM36720.1 - 1.3e-10 41.6 0.0 2.9e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAM36720.1 - 8.5e-08 32.5 0.0 2.9e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAM36720.1 - 0.00024 21.4 0.0 0.00079 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM36720.1 - 0.0034 17.7 0.0 0.024 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 GAM36720.1 - 0.0096 15.8 0.2 4.4 7.1 0.0 2.6 2 0 0 2 2 2 2 Helicase AAA_30 PF13604.6 GAM36720.1 - 0.044 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain HHH_5 PF14520.6 GAM36720.1 - 0.075 13.6 0.1 0.21 12.2 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain AAA PF00004.29 GAM36720.1 - 0.13 12.7 0.0 0.39 11.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 GAM36720.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Nuc_sug_transp PF04142.15 GAM36721.1 - 5.2e-80 269.0 7.6 6.6e-80 268.6 7.6 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 GAM36721.1 - 6 6.1 13.5 0.72 9.1 0.7 2.8 2 1 0 2 2 2 0 Triose-phosphate Transporter family Abhydrolase_3 PF07859.13 GAM36723.1 - 3.9e-28 98.8 0.0 5.3e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAM36723.1 - 1.8e-12 46.8 0.0 2.1e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 GAM36723.1 - 0.014 14.9 0.0 0.095 12.2 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family MFS_1 PF07690.16 GAM36724.1 - 6.5e-37 127.3 54.9 5.3e-36 124.3 54.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM36724.1 - 8.6e-09 34.8 12.1 8.6e-09 34.8 12.1 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter adh_short PF00106.25 GAM36725.1 - 1.4e-23 83.4 0.0 1.8e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM36725.1 - 2e-13 50.4 0.0 2.5e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAM36725.1 - 9.4e-05 22.0 0.0 0.00018 21.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAM36725.1 - 0.00014 21.9 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 GAM36725.1 - 0.058 12.6 0.0 0.62 9.2 0.0 2.5 2 1 0 2 2 2 0 Male sterility protein BES1_N PF05687.13 GAM36725.1 - 0.075 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal LRR_6 PF13516.6 GAM36726.1 - 1.4e-05 24.7 2.5 1.5 9.1 0.1 3.7 3 0 0 3 3 3 3 Leucine Rich repeat LRR_4 PF12799.7 GAM36726.1 - 0.00063 20.1 1.2 0.014 15.8 1.0 2.8 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM36726.1 - 0.0015 18.2 0.6 2.6 7.9 0.2 3.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 GAM36726.1 - 0.0022 18.3 0.4 3.8 8.4 0.1 4.1 2 1 1 3 3 3 2 Leucine Rich Repeat WD40 PF00400.32 GAM36727.1 - 1.3e-41 139.8 14.9 5.4e-06 27.0 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 GAM36727.1 - 1.4e-08 34.5 0.1 3e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM36727.1 - 8.2e-08 31.9 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 GAM36727.1 - 2.6e-07 30.9 1.0 0.49 10.7 0.0 4.9 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 GAM36727.1 - 0.00018 21.5 0.0 2.9 7.9 0.0 4.3 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 GAM36727.1 - 0.0019 16.9 6.9 5.6 5.5 0.1 5.3 5 1 1 6 6 6 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 GAM36727.1 - 0.0072 15.9 0.8 2.1 7.9 0.2 2.8 2 1 0 2 2 2 1 PQQ-like domain WD40_like PF17005.5 GAM36727.1 - 0.024 14.0 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain F-box_4 PF15966.5 GAM36727.1 - 0.071 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 F-box Acid_PPase PF12689.7 GAM36728.1 - 2.2e-71 239.1 0.0 2.5e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 GAM36728.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase HAD_2 PF13419.6 GAM36728.1 - 0.11 12.6 0.0 0.8 9.8 0.0 2.1 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase TPR_MLP1_2 PF07926.12 GAM36729.1 - 6.6e-34 116.7 32.7 6.6e-34 116.7 32.7 18.7 7 7 10 18 18 18 6 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 GAM36729.1 - 0.00015 21.7 28.1 0.00015 21.7 28.1 13.5 6 4 5 13 13 13 2 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 GAM36729.1 - 0.0055 16.7 16.6 0.0055 16.7 16.6 17.3 5 4 14 19 19 19 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Zn_clus PF00172.18 GAM36729.1 - 0.0094 16.0 3.0 0.019 15.1 3.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFA2_Winged_2 PF18121.1 GAM36730.1 - 2.6e-23 81.5 3.8 8.7e-23 79.8 0.5 2.6 3 0 0 3 3 3 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 GAM36730.1 - 1.8e-20 73.0 0.3 1.4e-19 70.1 0.0 2.5 3 0 0 3 3 3 1 TFIIE beta subunit core domain DHBP_synthase PF00926.19 GAM36731.1 - 1.1e-76 256.6 0.0 1.3e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase F-box-like PF12937.7 GAM36732.1 - 1.7e-08 34.2 0.3 3.4e-08 33.3 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM36732.1 - 3.6e-06 26.7 0.2 7.8e-06 25.6 0.2 1.6 1 0 0 1 1 1 1 F-box domain Abhydrolase_6 PF12697.7 GAM36733.1 - 6.3e-17 62.9 0.0 7.5e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM36733.1 - 6.3e-07 28.9 0.0 0.0011 18.3 0.0 2.9 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM36733.1 - 0.0004 20.1 0.0 0.00092 18.9 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 GAM36733.1 - 0.0036 17.1 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 GAM36733.1 - 0.0071 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 GAM36733.1 - 0.0092 15.8 0.0 0.022 14.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.8 GAM36733.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 GAM36733.1 - 0.052 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.12 GAM36733.1 - 0.057 13.4 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Pkinase PF00069.25 GAM36734.1 - 1.4e-60 204.9 0.0 1.8e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM36734.1 - 1.5e-27 96.5 0.0 2.3e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ferritin_2 PF13668.6 GAM36734.1 - 1.3e-22 80.4 0.2 2.9e-22 79.3 0.2 1.6 1 0 0 1 1 1 1 Ferritin-like domain Kinase-like PF14531.6 GAM36734.1 - 2.9e-08 33.4 0.0 5.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM36734.1 - 0.015 14.7 0.0 0.086 12.2 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.26 GAM36735.1 - 1.8e-49 167.0 0.0 2.1e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM36735.1 - 4.4e-05 23.2 0.0 6.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAM36735.1 - 0.00052 20.3 0.0 0.001 19.4 0.0 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 GAM36735.1 - 0.0039 17.0 0.0 0.0058 16.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain Methyltransf_11 PF08241.12 GAM36736.1 - 6.1e-09 36.4 0.0 9.5e-08 32.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM36736.1 - 6.2e-08 33.3 0.3 1e-06 29.3 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM36736.1 - 3e-06 27.1 0.0 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM36736.1 - 0.0005 19.9 0.0 0.00078 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM36736.1 - 0.00085 20.0 0.0 0.013 16.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 GAM36737.1 - 9e-39 133.4 58.4 4.5e-38 131.1 58.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 GAM36738.1 - 4.2e-55 187.4 0.0 5.4e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM36738.1 - 6.4e-08 32.6 1.0 0.00053 19.7 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM36738.1 - 2.7e-07 29.6 0.0 9.9e-05 21.2 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 GAM36738.1 - 6.6e-05 23.4 0.7 0.043 14.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM36738.1 - 0.00012 21.3 0.2 0.021 13.9 0.1 2.7 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 GAM36738.1 - 0.00051 19.4 0.0 0.0008 18.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 GAM36738.1 - 0.0012 17.9 0.0 0.0039 16.3 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 GAM36738.1 - 0.0013 18.1 0.0 0.04 13.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM36738.1 - 0.0018 18.5 0.2 0.0057 16.9 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 GAM36738.1 - 0.0042 16.7 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 GAM36738.1 - 0.0085 15.4 0.3 0.033 13.4 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 GAM36738.1 - 0.02 14.0 0.1 0.042 12.9 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein adh_short PF00106.25 GAM36739.1 - 3.9e-33 114.6 0.0 4.8e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM36739.1 - 1.6e-23 83.5 0.0 2e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM36739.1 - 0.00029 20.8 0.0 0.00063 19.7 0.0 1.5 1 1 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 GAM36740.1 - 1.5e-58 198.3 0.0 2e-36 125.9 0.1 3.2 2 1 1 3 3 3 3 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAM36740.1 - 4.3e-31 107.4 0.0 7.7e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAM36740.1 - 2.3e-14 53.8 0.0 5.1e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 GAM36740.1 - 2.2e-06 27.2 0.2 5.8e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 GAM36740.1 - 0.0038 17.0 0.4 0.12 12.3 0.2 2.7 1 1 1 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EthD PF07110.11 GAM36741.1 - 1e-19 71.5 0.2 1.3e-19 71.1 0.2 1.2 1 0 0 1 1 1 1 EthD domain Mannitol_dh_C PF08125.13 GAM36741.1 - 0.054 13.0 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain MFS_1 PF07690.16 GAM36742.1 - 1.8e-39 135.7 55.9 5.3e-39 134.1 55.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM36742.1 - 1.5e-15 56.7 13.2 2.2e-15 56.1 13.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM36742.1 - 1.8e-07 30.4 17.2 1.8e-07 30.4 17.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1772 PF08592.11 GAM36744.1 - 3.9e-05 24.0 2.9 3.9e-05 24.0 2.9 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) A_deaminase PF00962.22 GAM36745.1 - 4.5e-24 85.4 0.0 6.5e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase ATG2_CAD PF13329.6 GAM36746.1 - 1.7e-45 154.5 0.7 6.7e-45 152.6 0.1 2.4 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 GAM36746.1 - 2.8e-31 107.7 0.0 8.4e-31 106.2 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 GAM36746.1 - 0.0058 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal DGF-1_C PF11040.8 GAM36746.1 - 0.014 15.4 0.3 49 4.0 0.0 4.2 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus TAXi_N PF14543.6 GAM36746.1 - 0.065 13.5 1.3 0.34 11.1 0.5 2.5 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal HET PF06985.11 GAM36747.1 - 8.3e-09 36.0 6.9 1.6e-07 31.8 0.8 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) UvrD_C PF13361.6 GAM36747.1 - 0.23 10.8 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Glyco_hydro_18 PF00704.28 GAM36748.1 - 5.9e-63 213.5 3.8 9.3e-63 212.8 3.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 GAM36748.1 - 5.7e-11 42.3 0.0 1.7e-05 24.8 0.0 2.8 2 0 0 2 2 2 2 LysM domain Tis11B_N PF04553.12 GAM36749.1 - 0.17 12.5 4.3 12 6.5 0.1 3.0 2 1 1 3 3 3 0 Tis11B like protein, N terminus CN_hydrolase PF00795.22 GAM36750.1 - 6e-59 199.5 0.0 7.3e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L31e PF01198.19 GAM36750.1 - 2.8e-39 133.2 0.4 4.4e-39 132.6 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e Nucleoporin_FG PF13634.6 GAM36751.1 - 6.5e-11 42.9 229.2 0.0028 18.5 19.8 12.3 4 2 6 10 10 10 5 Nucleoporin FG repeat region Ran_BP1 PF00638.18 GAM36751.1 - 4e-10 40.0 0.0 7.6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Peptidase_M24 PF00557.24 GAM36752.1 - 1.2e-39 136.2 0.0 1.8e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 GAM36752.1 - 0.023 14.8 3.0 0.031 14.4 3.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein PGA2 PF07543.12 GAM36752.1 - 0.86 9.6 6.9 0.18 11.8 3.6 1.6 2 0 0 2 2 2 0 Protein trafficking PGA2 ABC2_membrane PF01061.24 GAM36753.1 - 3.5e-86 288.0 43.3 9.9e-48 162.3 18.1 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 GAM36753.1 - 8.5e-38 130.0 0.0 4.1e-18 66.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAM36753.1 - 2e-26 91.7 10.7 4.9e-25 87.2 0.1 3.6 3 0 0 3 3 3 2 CDR ABC transporter AAA_16 PF13191.6 GAM36753.1 - 2.3e-06 28.1 0.0 0.0061 17.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 GAM36753.1 - 8.4e-06 25.1 38.9 0.0031 16.7 6.9 2.7 3 0 0 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GAM36753.1 - 2.1e-05 24.5 0.0 0.011 15.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_trans_N PF14510.6 GAM36753.1 - 5.5e-05 23.7 0.0 0.00018 22.0 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 GAM36753.1 - 0.00014 21.5 0.1 0.0057 16.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAM36753.1 - 0.00051 20.3 0.1 0.74 10.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 GAM36753.1 - 0.00054 20.1 0.3 1.4 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GAM36753.1 - 0.0006 19.5 0.4 0.089 12.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 GAM36753.1 - 0.0037 17.8 0.0 2.1 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 GAM36753.1 - 0.0051 16.4 1.2 2 8.0 0.4 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 GAM36753.1 - 0.012 15.9 1.0 0.83 9.9 0.5 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAM36753.1 - 0.018 15.0 0.1 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 GAM36753.1 - 0.051 12.8 0.3 4.3 6.6 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 GAM36753.1 - 0.069 12.9 0.3 5.2 6.7 0.3 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 GAM36753.1 - 0.072 12.1 0.1 0.58 9.2 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 GAM36753.1 - 0.1 12.7 0.2 24 5.1 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 GAM36753.1 - 0.17 12.3 0.1 11 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Med7 PF05983.11 GAM36754.1 - 4.9e-64 215.9 0.5 6.1e-64 215.6 0.5 1.1 1 0 0 1 1 1 1 MED7 protein SMC_ScpB PF04079.16 GAM36754.1 - 0.049 13.3 0.2 0.097 12.3 0.2 1.4 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB Ferric_reduct PF01794.19 GAM36755.1 - 1.3e-20 73.8 14.6 1.3e-20 73.8 14.6 2.9 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAM36755.1 - 2.5e-15 56.9 0.0 3.9e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAM36755.1 - 6.8e-12 45.4 0.0 1.5e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 GAM36755.1 - 4.7e-05 23.8 11.3 0.0031 18.0 2.0 3.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4405) PAP2 PF01569.21 GAM36757.1 - 3.2e-28 98.2 0.4 3.2e-28 98.2 0.4 1.7 2 0 0 2 2 2 1 PAP2 superfamily Frag1 PF10277.9 GAM36757.1 - 0.0004 20.0 2.3 0.0007 19.2 0.2 2.1 1 1 1 2 2 2 1 Frag1/DRAM/Sfk1 family SCP2 PF02036.17 GAM36758.1 - 4.4e-25 88.1 0.5 5.1e-25 87.9 0.5 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 GAM36758.1 - 0.0002 21.6 0.1 0.00027 21.2 0.0 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 GAM36758.1 - 0.0061 16.9 0.1 0.0074 16.7 0.1 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain Pectate_lyase_3 PF12708.7 GAM36760.1 - 1.3e-92 309.5 31.9 1.5e-81 273.4 10.5 3.8 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 GAM36760.1 - 4.5e-06 26.3 4.7 0.035 13.8 0.6 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase D-ser_dehydrat PF14031.6 GAM36761.1 - 1e-22 80.6 0.1 3.2e-22 79.0 0.0 1.9 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 GAM36761.1 - 3.4e-10 40.0 0.0 4.7e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Gti1_Pac2 PF09729.9 GAM36761.1 - 9.3e-05 22.6 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 Gti1/Pac2 family SLT PF01464.20 GAM36762.1 - 1.9e-10 40.4 0.5 5.1e-10 39.0 0.5 1.7 1 1 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 GAM36762.1 - 0.076 13.5 0.2 0.15 12.6 0.3 1.6 1 1 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Glyco_hydr_30_2 PF14587.6 GAM36763.1 - 1.4e-11 44.7 0.3 2.2e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 GAM36763.1 - 4.8e-10 39.5 2.4 1.3e-09 38.2 2.4 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 GAM36763.1 - 3.5e-08 32.8 0.0 8e-08 31.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 GAM36763.1 - 7.5e-08 32.0 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Aldedh PF00171.22 GAM36764.1 - 1.8e-138 462.0 0.0 2.1e-138 461.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3632 PF12311.8 GAM36765.1 - 5.1e-09 36.8 0.0 5.5e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Phage_tail_3 PF08813.11 GAM36765.1 - 0.051 13.2 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein, TTP TauD PF02668.16 GAM36766.1 - 3.3e-47 161.5 0.5 4.1e-47 161.2 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family VIR_N PF15912.5 GAM36767.1 - 0.36 10.4 5.8 0.72 9.4 5.8 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal Acyl_transf_3 PF01757.22 GAM36769.1 - 5.9e-23 81.5 28.6 2e-22 79.7 28.6 1.7 1 1 0 1 1 1 1 Acyltransferase family FPN1 PF06963.12 GAM36770.1 - 1.1e-104 350.4 16.7 1.5e-77 261.1 9.2 2.0 1 1 1 2 2 2 2 Ferroportin1 (FPN1) MFS_1_like PF12832.7 GAM36770.1 - 0.0022 16.9 2.1 0.0033 16.4 2.1 1.4 1 0 0 1 1 1 1 MFS_1 like family Kelch_3 PF13415.6 GAM36771.1 - 2e-28 98.1 6.7 1.3e-07 31.7 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 GAM36771.1 - 9.5e-27 92.8 10.4 9e-15 54.4 0.0 6.6 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM36771.1 - 1.9e-15 56.2 6.7 0.0043 16.6 0.0 7.2 7 0 0 7 7 7 3 Kelch motif Kelch_6 PF13964.6 GAM36771.1 - 2.3e-13 49.9 6.1 0.0078 16.5 0.1 6.0 5 1 1 6 6 6 3 Kelch motif Kelch_2 PF07646.15 GAM36771.1 - 3.5e-11 42.6 6.1 0.021 14.8 0.1 6.1 5 2 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 GAM36771.1 - 6.3e-10 38.8 0.3 0.082 12.9 0.0 5.3 5 0 0 5 5 5 3 Kelch motif PQQ_3 PF13570.6 GAM36771.1 - 1.3 9.6 11.7 24 5.6 0.0 5.8 6 2 0 6 6 6 0 PQQ-like domain p450 PF00067.22 GAM36772.1 - 3.9e-49 167.6 0.0 4.8e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kelch_5 PF13854.6 GAM36775.1 - 6.3e-13 48.4 0.3 8.4e-12 44.8 0.3 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 GAM36775.1 - 2.4e-06 27.0 0.2 0.21 11.2 0.0 4.4 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM36775.1 - 0.00069 19.6 7.4 1 9.4 0.0 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM36775.1 - 0.0098 16.1 5.1 0.11 12.8 0.5 3.7 3 1 1 4 4 4 1 Kelch motif SKG6 PF08693.10 GAM36775.1 - 0.77 9.2 9.5 2.3 7.7 9.5 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain AbiGi PF10899.8 GAM36777.1 - 0.094 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative abortive phage resistance protein AbiGi, antitoxin MFS_1 PF07690.16 GAM36778.1 - 2.9e-16 59.3 14.1 2.9e-16 59.3 14.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Casein_kappa PF00997.18 GAM36778.1 - 0.11 12.6 4.3 0.5 10.5 0.1 2.3 2 0 0 2 2 2 0 Kappa casein Mucin PF01456.17 GAM36778.1 - 2.5 8.1 14.1 7.5 6.5 14.1 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4131 PF13567.6 GAM36778.1 - 2.7 7.6 6.2 1.2 8.8 2.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) TctB PF07331.11 GAM36778.1 - 5.3 7.3 13.7 5.4 7.3 7.0 3.0 3 1 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family Aminotran_5 PF00266.19 GAM36779.1 - 1.7e-22 79.9 0.0 2.4e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GAM36779.1 - 0.00076 18.1 0.0 0.0013 17.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAM36779.1 - 0.0067 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAM36779.1 - 0.0075 15.6 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GAD PF02938.14 GAM36779.1 - 0.1 12.9 0.1 31 4.9 0.0 2.9 3 0 0 3 3 3 0 GAD domain Iso_dh PF00180.20 GAM36780.1 - 7.9e-87 291.6 0.0 9.5e-87 291.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4875 PF16175.5 GAM36780.1 - 0.025 14.7 0.0 0.058 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) Asp PF00026.23 GAM36781.1 - 4.7e-62 210.2 4.5 6.1e-62 209.9 4.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM36781.1 - 5.1e-06 26.8 12.5 2.5e-05 24.6 1.1 3.6 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 GAM36781.1 - 0.00098 19.6 2.0 0.59 10.7 0.0 3.3 4 0 0 4 4 4 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GAM36781.1 - 0.0016 19.1 9.2 0.022 15.4 0.1 3.8 4 1 0 4 4 4 2 Aspartyl protease TAXi_C PF14541.6 GAM36781.1 - 0.026 14.3 0.0 1.3 8.7 0.0 2.4 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal AA_permease PF00324.21 GAM36782.1 - 8.2e-124 413.8 33.9 9.2e-124 413.6 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM36782.1 - 2.6e-36 125.4 38.0 3.1e-36 125.1 38.0 1.0 1 0 0 1 1 1 1 Amino acid permease RTA1 PF04479.13 GAM36783.1 - 6e-39 133.8 4.1 8.3e-39 133.3 4.1 1.2 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.18 GAM36784.1 - 2e-09 37.4 11.3 3.7e-09 36.6 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAM36785.1 - 5.2e-10 38.7 0.3 1.3e-09 37.4 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_10 PF13673.7 GAM36786.1 - 9.3e-08 32.1 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM36786.1 - 2.4e-07 31.1 0.0 4.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM36786.1 - 2.3e-05 24.5 0.2 0.002 18.2 0.2 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM36786.1 - 0.00015 22.0 0.0 0.00022 21.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_15 PF17013.5 GAM36786.1 - 0.045 13.2 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase PLDc_2 PF13091.6 GAM36787.1 - 1.6e-18 66.8 0.3 4.2e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.8 GAM36787.1 - 0.0095 15.1 0.1 0.067 12.4 0.0 2.3 2 0 0 2 2 2 1 Archaeal transcriptional regulator TrmB PLDc PF00614.22 GAM36787.1 - 0.013 15.6 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Phospholipase D Active site motif Peptidase_A4 PF01828.17 GAM36788.1 - 4.5e-81 271.3 15.1 4.5e-81 271.3 15.1 1.8 2 0 0 2 2 2 1 Peptidase A4 family FMO-like PF00743.19 GAM36788.1 - 2.4e-38 131.9 0.0 4.8e-21 74.8 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAM36788.1 - 1.2e-13 50.9 0.0 3e-13 49.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM36788.1 - 1.4e-13 50.8 1.0 4.3e-09 36.1 0.4 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM36788.1 - 9.5e-10 38.1 1.2 4.3e-08 32.7 0.5 2.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAM36788.1 - 1.9e-08 34.4 3.1 1.4e-07 31.6 1.2 3.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 GAM36788.1 - 4.5e-08 33.1 0.2 0.0056 16.3 0.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM36788.1 - 9.9e-08 32.1 0.0 4e-07 30.2 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAM36788.1 - 4e-05 23.0 0.0 0.0023 17.2 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 GAM36788.1 - 0.021 14.1 0.0 0.63 9.3 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 GAM36788.1 - 0.057 12.5 0.2 0.68 8.9 0.1 2.3 3 0 0 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 GAM36788.1 - 0.057 12.8 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAM36788.1 - 0.077 12.2 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 GAM36788.1 - 0.1 11.3 0.2 0.23 10.2 0.0 1.6 2 0 0 2 2 2 0 MCRA family Pyr_redox PF00070.27 GAM36788.1 - 0.1 13.1 2.7 0.43 11.2 0.1 2.9 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM36788.1 - 0.14 10.9 1.2 0.24 10.0 0.4 1.8 2 0 0 2 2 2 0 HI0933-like protein DUF4965 PF16335.5 GAM36789.1 - 1.4e-41 142.0 0.0 2.6e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 GAM36789.1 - 1.3e-37 129.8 5.8 2e-37 129.2 5.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 GAM36789.1 - 2.4e-13 50.8 5.4 8.3e-11 42.6 2.9 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF1793) Glyco_hydr_116N PF12215.8 GAM36789.1 - 0.0065 16.0 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term FMN_bind_2 PF04299.12 GAM36790.1 - 1.9e-59 200.1 0.1 2.3e-59 199.9 0.1 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Ammonium_transp PF00909.21 GAM36791.1 - 1.1e-65 221.9 16.2 9.9e-65 218.8 16.2 1.9 1 1 0 1 1 1 1 Ammonium Transporter Family Methyltransf_23 PF13489.6 GAM36792.1 - 1.8e-12 47.4 0.0 2.9e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM36792.1 - 0.00056 20.6 0.1 0.011 16.4 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM36792.1 - 0.0039 17.9 0.1 0.061 14.1 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM36792.1 - 0.0058 17.3 0.0 0.019 15.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM36792.1 - 0.028 14.2 0.0 8.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 GAM36792.1 - 0.035 13.4 0.0 0.18 11.1 0.0 2.1 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family FAD_binding_3 PF01494.19 GAM36793.1 - 2.7e-15 56.5 0.2 1.5e-09 37.5 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAM36793.1 - 2.2e-07 30.4 0.0 0.01 15.1 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM36793.1 - 1.1e-05 25.6 0.1 3.9e-05 23.8 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAM36793.1 - 5.4e-05 23.7 0.1 0.021 15.4 0.0 3.1 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM36793.1 - 0.0014 17.4 0.1 0.0039 15.9 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 GAM36793.1 - 0.0019 17.8 0.1 0.018 14.6 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM36793.1 - 0.0041 16.3 0.1 0.0099 15.0 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 GAM36793.1 - 0.0084 15.2 0.0 0.097 11.7 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 GAM36793.1 - 0.01 15.8 0.0 0.4 10.7 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 GAM36793.1 - 0.013 14.8 0.1 0.022 14.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 GAM36793.1 - 0.043 13.1 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 GAM36793.1 - 0.056 12.7 0.0 0.56 9.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 GAM36793.1 - 0.12 11.4 0.0 0.27 10.2 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Fungal_trans PF04082.18 GAM36794.1 - 2.4e-07 30.1 0.8 1.1e-06 27.9 0.8 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM36794.1 - 0.00016 21.8 10.2 0.00025 21.1 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 GAM36795.1 - 3.7e-42 144.5 0.0 4.6e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Gyro_capsid PF04162.12 GAM36795.1 - 0.054 12.0 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) CTV_P13 PF06922.11 GAM36795.1 - 0.079 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein Epimerase PF01370.21 GAM36796.1 - 3.5e-06 26.7 0.0 2e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM36796.1 - 0.00079 19.4 0.1 0.0039 17.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 GAM36796.1 - 0.0043 16.6 0.0 0.37 10.3 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 GAM36796.1 - 0.0046 17.2 0.0 0.0087 16.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 GAM36796.1 - 0.075 12.9 0.1 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 KR domain Semialdhyde_dh PF01118.24 GAM36796.1 - 0.12 12.8 0.5 0.25 11.8 0.5 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CbiJ PF02571.14 GAM36796.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.5 2 0 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK RmlD_sub_bind PF04321.17 GAM36796.1 - 0.22 10.6 0.0 6.1 5.9 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Fungal_trans_2 PF11951.8 GAM36797.1 - 7.3e-06 25.0 0.7 3.8e-05 22.7 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.25 GAM36798.1 - 1e-21 77.3 0.1 2.1e-18 66.5 0.5 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM36798.1 - 2.1e-14 53.7 0.7 2.6e-11 43.5 1.3 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM36798.1 - 3.8e-12 46.5 0.6 5e-12 46.1 0.6 1.2 1 0 0 1 1 1 1 KR domain DUF5429 PF17494.2 GAM36798.1 - 0.012 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5429) TPR_12 PF13424.6 GAM36800.1 - 1.6e-07 31.5 10.8 0.089 13.1 0.0 7.6 6 1 0 6 6 6 2 Tetratricopeptide repeat AAA_16 PF13191.6 GAM36800.1 - 2.2e-07 31.4 6.7 3.6e-07 30.7 0.0 4.0 4 0 0 4 4 4 1 AAA ATPase domain TPR_10 PF13374.6 GAM36800.1 - 4.2e-07 29.6 7.5 0.0076 16.1 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat NACHT PF05729.12 GAM36800.1 - 5.5e-05 23.1 0.0 0.0016 18.4 0.0 3.1 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 GAM36800.1 - 7.3e-05 23.1 0.0 0.0013 19.0 0.0 3.3 2 1 0 2 2 2 1 AAA domain TPR_3 PF07720.12 GAM36800.1 - 0.0047 16.9 0.1 1 9.4 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA PF00004.29 GAM36800.1 - 0.0084 16.5 0.7 0.1 13.1 0.0 3.4 2 2 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) ComGF PF15980.5 GAM36800.1 - 0.062 13.7 0.2 0.49 10.8 0.2 2.6 1 0 0 1 1 1 0 Putative Competence protein ComGF AAA_18 PF13238.6 GAM36800.1 - 0.073 13.6 0.0 1.9 9.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain TPR_16 PF13432.6 GAM36800.1 - 0.35 11.5 1.6 1.4 9.6 0.0 3.0 3 0 0 3 3 1 0 Tetratricopeptide repeat ABC_tran PF00005.27 GAM36800.1 - 0.57 10.7 2.4 1.5 9.4 0.0 3.0 3 0 0 3 3 3 0 ABC transporter DUF1866 PF08952.11 GAM36800.1 - 1.6 8.6 5.4 0.19 11.6 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) adh_short PF00106.25 GAM36801.1 - 5.3e-16 58.7 1.9 6.4e-16 58.4 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM36801.1 - 3.9e-13 49.5 1.4 5e-13 49.2 1.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM36801.1 - 1.2e-08 35.1 0.8 1.4e-08 34.8 0.8 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAM36801.1 - 0.045 13.1 1.0 0.09 12.1 1.0 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Flagellin_IN PF07196.13 GAM36801.1 - 0.19 12.0 2.9 0.34 11.2 2.9 1.5 1 0 0 1 1 1 0 Flagellin hook IN motif Zn_clus PF00172.18 GAM36802.1 - 1.1e-07 31.9 4.5 1.9e-07 31.0 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PP-binding_2 PF14573.6 GAM36802.1 - 0.017 15.3 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Acyl-carrier GST_C PF00043.25 GAM36803.1 - 1.6e-08 34.6 0.0 2.1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM36803.1 - 4e-08 33.6 0.0 8.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM36803.1 - 6.3e-07 29.3 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM36803.1 - 2e-06 28.0 0.0 5e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAM36803.1 - 8.1e-06 26.1 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM36803.1 - 9.1e-05 22.6 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SLT PF01464.20 GAM36804.1 - 0.087 12.5 0.2 1.2 8.8 0.2 2.3 1 1 0 1 1 1 0 Transglycosylase SLT domain Glyco_hydro_2_C PF02836.17 GAM36805.1 - 2.3e-102 342.2 1.1 3.3e-102 341.7 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 GAM36805.1 - 1.5e-56 191.8 0.0 2.7e-56 190.9 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 GAM36805.1 - 1.4e-43 148.8 0.1 3e-43 147.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 GAM36805.1 - 2.2e-22 79.3 0.0 6.4e-22 77.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 GAM36805.1 - 1.6e-05 25.5 0.1 0.00015 22.4 0.0 2.6 2 1 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_72 PF03198.14 GAM36805.1 - 0.066 12.5 0.7 1.4 8.1 0.1 2.8 2 1 1 3 3 3 0 Glucanosyltransferase Sugar_tr PF00083.24 GAM36806.1 - 3.3e-73 247.1 19.6 3.9e-73 246.9 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM36806.1 - 5.6e-27 94.6 21.9 7.4e-27 94.2 21.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM36806.1 - 0.0015 17.1 0.8 0.0015 17.1 0.8 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) 7tm_1 PF00001.21 GAM36806.1 - 0.004 16.5 0.1 0.0072 15.7 0.1 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FAD_binding_4 PF01565.23 GAM36808.1 - 1.6e-21 76.5 0.1 2.5e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM36808.1 - 0.0002 21.4 0.0 0.00068 19.7 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like DUF4874 PF16173.5 GAM36809.1 - 1.1e-12 47.9 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4874) DUF4832 PF16116.5 GAM36809.1 - 0.00057 19.8 0.1 0.00085 19.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4832) 3Beta_HSD PF01073.19 GAM36810.1 - 6.8e-47 159.8 0.0 9e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM36810.1 - 1.5e-23 83.5 0.1 1.8e-23 83.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM36810.1 - 9.1e-13 48.3 0.0 1.4e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GAM36810.1 - 1.1e-11 44.4 0.0 8.1e-07 28.5 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 GAM36810.1 - 4e-05 22.8 0.0 5.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 GAM36810.1 - 0.004 17.1 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF4242 PF14026.6 GAM36810.1 - 0.012 15.7 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) Ldh_2 PF02615.14 GAM36811.1 - 1.6e-42 145.9 0.0 5.8e-23 81.6 0.1 2.2 2 0 0 2 2 2 2 Malate/L-lactate dehydrogenase Abhydrolase_3 PF07859.13 GAM36812.1 - 7.4e-32 110.9 0.0 1.1e-31 110.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAM36812.1 - 0.0028 16.6 0.0 0.0039 16.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 GAM36812.1 - 0.0077 15.1 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Carboxylesterase family DUF1115 PF06544.12 GAM36814.1 - 8.8e-12 45.3 0.0 1.3e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Peptidase_M28 PF04389.17 GAM36815.1 - 2e-37 128.8 0.0 2.8e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 GAM36815.1 - 2.9e-11 43.2 0.0 6.2e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 GAM36815.1 - 0.0071 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MAPEG PF01124.18 GAM36816.1 - 2.5e-15 56.5 3.1 3.1e-15 56.2 3.1 1.1 1 0 0 1 1 1 1 MAPEG family DUF3425 PF11905.8 GAM36817.1 - 5.1e-10 39.4 9.0 1.6e-08 34.6 9.0 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Abhydrolase_1 PF00561.20 GAM36818.1 - 1.9e-19 70.3 0.0 3.8e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM36818.1 - 1.1e-12 49.1 0.1 2.4e-12 48.0 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM36818.1 - 2.8e-11 43.1 0.0 4.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 GAM36818.1 - 0.038 14.1 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Rop PF01815.16 GAM36818.1 - 0.18 11.7 0.1 0.55 10.2 0.1 1.7 2 0 0 2 2 2 0 Rop protein Sugar_tr PF00083.24 GAM36819.1 - 3.8e-96 322.7 17.4 4.3e-96 322.5 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM36819.1 - 2.1e-16 59.8 23.6 2.1e-16 59.8 23.6 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM36819.1 - 5.4e-06 25.2 16.1 0.0019 16.9 2.6 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 GAM36819.1 - 5.1 5.9 14.1 0.5 9.2 4.3 2.2 2 0 0 2 2 2 0 MFS_1 like family Alpha-amylase PF00128.24 GAM36820.1 - 1.1e-111 373.7 0.0 1.7e-111 373.1 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 GAM36820.1 - 0.0017 17.5 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_42C PF08533.10 GAM36820.1 - 0.16 11.7 0.1 0.41 10.4 0.1 1.7 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain Zn_clus PF00172.18 GAM36821.1 - 2.6e-07 30.6 10.9 2.6e-07 30.6 10.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM36821.1 - 1.5e-05 24.2 0.1 2.1e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 GAM36822.1 - 2.2e-32 111.7 2.0 3.3e-32 111.1 2.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM36822.1 - 5e-07 29.7 0.1 1e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Pyr_redox_2 PF07992.14 GAM36823.1 - 3.7e-46 157.7 0.4 5e-46 157.3 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM36823.1 - 1e-14 54.8 1.9 1.3e-12 48.1 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 GAM36823.1 - 7.3e-11 42.5 0.1 2.4e-10 40.9 0.1 2.0 1 0 0 1 1 1 1 Rhodanese-like domain Pyr_redox_3 PF13738.6 GAM36823.1 - 6e-09 35.6 2.6 8.5e-05 22.0 0.4 3.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAM36823.1 - 1.2e-07 31.9 0.0 5.7e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain NAD_binding_8 PF13450.6 GAM36823.1 - 4.3e-07 30.1 1.3 0.021 15.1 0.1 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAM36823.1 - 5.5e-06 25.3 1.6 0.19 10.4 0.1 3.8 3 1 1 4 4 4 3 HI0933-like protein AlaDh_PNT_C PF01262.21 GAM36823.1 - 3.5e-05 23.2 0.0 0.0046 16.3 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 GAM36823.1 - 9.7e-05 22.1 6.0 0.08 12.5 0.6 3.2 3 1 0 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM36823.1 - 0.00016 20.9 3.4 0.037 13.1 0.4 3.1 4 0 0 4 4 4 2 FAD binding domain Trp_halogenase PF04820.14 GAM36823.1 - 0.0003 19.8 2.0 0.22 10.3 0.1 3.1 2 1 1 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.12 GAM36823.1 - 0.0026 16.9 1.0 8.5 5.3 0.0 3.1 2 1 1 3 3 3 1 Lycopene cyclase protein FAD_oxidored PF12831.7 GAM36823.1 - 0.0027 17.1 2.0 0.0066 15.8 0.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.18 GAM36823.1 - 0.0034 17.6 0.7 0.22 11.8 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 GAM36823.1 - 0.0052 17.2 0.2 0.87 10.1 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.22 GAM36823.1 - 0.044 12.9 1.6 7.5 5.5 0.3 2.8 2 1 1 3 3 3 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAM36823.1 - 0.66 9.2 4.0 0.91 8.7 0.2 2.8 2 2 1 3 3 3 0 FAD binding domain PPDK_N PF01326.19 GAM36825.1 - 1.8e-111 372.6 0.0 2.8e-111 371.9 0.0 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 GAM36825.1 - 1.1e-50 172.5 0.0 1.7e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain Ldh_1_N PF00056.23 GAM36825.1 - 8.1e-26 90.8 0.3 1.3e-25 90.1 0.3 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain PEP-utilizers PF00391.23 GAM36825.1 - 1.2e-24 85.8 0.8 3.5e-24 84.3 0.4 2.1 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain Ldh_1_C PF02866.18 GAM36825.1 - 2.6e-16 60.0 0.0 6e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 GAM36825.1 - 0.0082 15.7 0.2 0.2 11.2 0.0 2.5 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase ApbA PF02558.16 GAM36825.1 - 0.037 13.7 0.2 0.092 12.4 0.2 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 GAM36825.1 - 0.076 13.6 0.1 0.33 11.6 0.1 2.2 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SidC_N PF18219.1 GAM36825.1 - 0.1 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 SidC N-terminal domain ThiF PF00899.21 GAM36825.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 ThiF family Acyl_transf_3 PF01757.22 GAM36826.1 - 4.5e-32 111.5 40.4 5.6e-32 111.1 40.4 1.1 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.15 GAM36827.1 - 1e-11 45.3 0.1 2.6e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif ketoacyl-synt PF00109.26 GAM36828.1 - 1.1e-73 248.0 0.0 2.1e-73 247.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAM36828.1 - 8e-52 175.7 0.1 1.6e-51 174.7 0.1 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 GAM36828.1 - 1.4e-47 162.4 0.8 2.5e-47 161.6 0.8 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAM36828.1 - 4.6e-42 144.6 0.5 8.9e-42 143.7 0.5 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM36828.1 - 6.7e-31 106.7 0.0 2.2e-30 105.1 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 GAM36828.1 - 1e-18 67.9 0.0 3.3e-18 66.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM36828.1 - 8e-15 55.3 0.0 2.8e-14 53.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAM36828.1 - 2.2e-14 53.9 0.0 5.5e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 GAM36828.1 - 1.9e-12 47.3 0.0 1.7e-11 44.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM36828.1 - 3.6e-12 46.8 0.0 1.1e-11 45.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 GAM36828.1 - 2.2e-11 43.6 0.0 6.1e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_31 PF13847.6 GAM36828.1 - 4.2e-10 39.6 0.0 9.4e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM36828.1 - 7e-06 25.5 0.0 1.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 GAM36828.1 - 0.00021 21.6 0.0 0.00058 20.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 GAM36828.1 - 0.00053 19.4 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 GAM36828.1 - 0.0017 18.1 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_33 PF10017.9 GAM36828.1 - 0.0036 16.5 0.0 0.012 14.8 0.0 1.8 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_24 PF13578.6 GAM36828.1 - 0.059 14.4 0.0 0.24 12.5 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 GAM36829.1 - 2.6e-07 30.7 0.0 4.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM36829.1 - 3.7e-06 26.8 0.2 1.6e-05 24.8 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cep57_MT_bd PF06657.13 GAM36830.1 - 0.03 14.7 0.8 0.12 12.8 0.3 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Coat_F PF07875.12 GAM36830.1 - 0.083 13.1 2.1 7.6 6.8 0.1 2.7 3 0 0 3 3 3 0 Coat F domain Fungal_trans_2 PF11951.8 GAM36830.1 - 0.12 11.2 1.0 0.25 10.1 0.9 1.5 1 1 1 2 2 2 0 Fungal specific transcription factor domain Methyltransf_12 PF08242.12 GAM36831.1 - 1.5e-08 35.2 0.0 2.9e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM36831.1 - 2e-06 27.7 0.0 2.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM36831.1 - 6.1e-06 26.8 0.0 1.6e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM36831.1 - 0.00051 19.9 0.0 0.0013 18.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM36831.1 - 0.015 15.9 0.0 0.045 14.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 GAM36831.1 - 0.13 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain MFS_1 PF07690.16 GAM36832.1 - 2.3e-41 141.9 47.4 2.3e-41 141.9 47.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM36832.1 - 2.4e-13 49.4 14.4 2.4e-13 49.4 14.4 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 GAM36832.1 - 2.2 8.5 6.0 0.33 11.1 0.8 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 p450 PF00067.22 GAM36833.1 - 1.4e-52 179.0 0.0 1.7e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.7 GAM36834.1 - 2.4e-09 38.1 0.2 3.3e-09 37.7 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 GAM36834.1 - 2.1e-08 34.4 0.0 2.7e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 GAM36834.1 - 3.2e-08 33.1 0.0 3.3e-08 33.1 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 GAM36834.1 - 1.1e-07 31.8 0.0 1.2e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 GAM36834.1 - 1.3e-07 31.5 0.0 1.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM36834.1 - 2.1e-07 30.6 0.0 4.1e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 GAM36834.1 - 1.2e-05 25.0 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF1100 PF06500.11 GAM36834.1 - 1.4e-05 24.1 0.0 1.9e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.12 GAM36834.1 - 3.4e-05 22.7 0.0 0.00017 20.4 0.0 2.1 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 GAM36834.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 GAM36835.1 - 1.4e-44 152.5 46.6 1.6e-29 103.0 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM36835.1 - 3.4e-10 39.4 25.6 3e-09 36.3 5.0 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 GAM36835.1 - 2.2e-09 36.7 21.8 0.00018 20.5 8.8 3.0 1 1 2 3 3 3 3 MFS_1 like family MFS_4 PF06779.14 GAM36835.1 - 0.00024 20.5 37.5 0.00065 19.1 37.2 2.2 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PROL5-SMR PF15621.6 GAM36835.1 - 0.00027 21.4 0.0 0.00064 20.2 0.0 1.6 1 0 0 1 1 1 1 Proline-rich submaxillary gland androgen-regulated family TRI12 PF06609.13 GAM36835.1 - 0.0024 16.3 2.7 0.0024 16.3 2.7 2.9 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Rop PF01815.16 GAM36836.1 - 7.7e-35 118.6 2.0 8.9e-35 118.3 2.0 1.0 1 0 0 1 1 1 1 Rop protein N-SET PF11764.8 GAM36837.1 - 7e-53 179.3 0.1 2.4e-52 177.5 0.0 2.1 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 GAM36837.1 - 2.9e-27 94.1 0.4 6.5e-27 93.0 0.4 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated RRM_1 PF00076.22 GAM36837.1 - 0.00031 20.5 0.0 0.00062 19.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.28 GAM36837.1 - 0.047 14.1 0.4 0.25 11.7 0.0 2.4 3 0 0 3 3 3 0 SET domain VEGF_C PF14554.6 GAM36837.1 - 0.082 13.0 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 VEGF heparin-binding domain Rad60-SLD PF11976.8 GAM36838.1 - 2.9e-20 71.9 0.0 3.3e-19 68.5 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAM36838.1 - 0.00019 21.1 0.0 0.00041 20.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Merozoite_SPAM PF07133.11 GAM36838.1 - 2.2 8.3 9.2 6.6 6.7 9.2 1.9 1 1 0 1 1 1 0 Merozoite surface protein (SPAM) LSM PF01423.22 GAM36839.1 - 3.5e-16 58.7 0.0 5.6e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAM36839.1 - 0.0026 17.8 0.1 0.01 16.0 0.0 1.8 2 0 0 2 2 2 1 Ataxin 2 SM domain LSM14 PF12701.7 GAM36839.1 - 0.013 15.6 0.0 0.075 13.1 0.0 2.0 2 0 0 2 2 2 0 Scd6-like Sm domain Hfq PF17209.3 GAM36839.1 - 0.2 11.3 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Hfq protein IF-2B PF01008.17 GAM36840.1 - 2.9e-73 246.5 1.2 3.4e-73 246.3 1.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family SIS PF01380.22 GAM36841.1 - 3.9e-60 201.4 0.1 3e-32 111.2 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 GAM36841.1 - 8.6e-17 61.6 0.0 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAM36841.1 - 1.9e-10 40.7 0.0 4.4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 GAM36841.1 - 0.0035 16.3 0.0 0.0055 15.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Holin_BhlA PF10960.8 GAM36841.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 BhlA holin family DMRL_synthase PF00885.19 GAM36842.1 - 1.8e-55 186.6 2.2 3.4e-55 185.7 2.2 1.4 1 1 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase TolB_N PF04052.13 GAM36842.1 - 0.0019 18.4 0.5 0.4 10.9 0.1 2.2 2 0 0 2 2 2 2 TolB amino-terminal domain GalBD_like PF17974.1 GAM36842.1 - 0.098 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Galactose-binding domain-like Proteasome PF00227.26 GAM36843.1 - 2.8e-45 154.1 0.1 2.5e-32 111.9 0.0 2.3 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 GAM36843.1 - 5.3e-12 45.2 1.0 6.2e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Zn_Tnp_IS91 PF14319.6 GAM36844.1 - 9.1e-06 25.6 1.2 1.8e-05 24.7 1.2 1.5 1 0 0 1 1 1 1 Transposase zinc-binding domain Lar_restr_allev PF14354.6 GAM36844.1 - 0.012 16.0 1.2 0.025 14.9 1.2 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.6 GAM36844.1 - 0.33 10.7 3.2 4.6 7.1 1.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Iso_dh PF00180.20 GAM36845.1 - 7.3e-84 281.9 0.0 9.2e-84 281.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.8 GAM36846.1 - 5.2e-15 56.0 3.3 8.6e-15 55.3 3.3 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 GAM36846.1 - 1.4e-10 41.7 0.0 2.6e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM36846.1 - 7.6e-10 39.4 0.0 2.3e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM36846.1 - 0.00049 20.8 0.0 0.0013 19.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM36846.1 - 0.00051 19.9 0.0 0.00076 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAM36846.1 - 0.0032 17.2 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 GAM36846.1 - 0.08 12.2 0.0 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Erv26 PF04148.13 GAM36847.1 - 2.4e-93 311.6 0.1 2.8e-93 311.5 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF1970 PF09301.10 GAM36847.1 - 0.012 15.9 1.3 0.13 12.6 1.3 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1970) COX1 PF00115.20 GAM36847.1 - 0.019 13.9 1.9 0.024 13.5 1.9 1.0 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I RhoGAP PF00620.27 GAM36848.1 - 9.9e-41 139.1 0.1 2e-40 138.1 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 GAM36848.1 - 1.3e-13 51.4 0.0 3.1e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 GAM36848.1 - 0.12 12.7 0.0 0.7 10.2 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain MDM31_MDM32 PF08118.11 GAM36849.1 - 2.6e-228 759.0 0.1 3.2e-228 758.7 0.1 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins TraH_2 PF06871.11 GAM36849.1 - 0.011 15.4 0.3 0.019 14.6 0.3 1.3 1 0 0 1 1 1 0 TraH_2 Peptidase_M61 PF05299.12 GAM36849.1 - 0.1 13.0 0.0 3.2 8.2 0.0 2.5 2 0 0 2 2 2 0 M61 glycyl aminopeptidase KH_8 PF17903.1 GAM36850.1 - 4.2e-05 23.6 0.0 9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 GAM36850.1 - 0.0076 16.1 0.3 0.017 14.9 0.3 1.6 1 0 0 1 1 1 1 KH domain Proteasome PF00227.26 GAM36851.1 - 1e-31 109.9 0.0 7.5e-31 107.1 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit HCNGP PF07818.13 GAM36852.1 - 1.3e-27 96.3 0.1 1.9e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.26 GAM36853.1 - 3.9e-28 98.2 0.0 4.6e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit FAA_hydrolase PF01557.18 GAM36854.1 - 1.5e-63 214.4 0.0 1.9e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.15 GAM36855.1 - 5.5e-17 61.6 2.2 3.4e-16 59.0 2.7 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) HSP20 PF00011.21 GAM36855.1 - 1.2e-13 51.0 0.2 8.7e-10 38.7 0.1 2.5 1 1 0 2 2 2 2 Hsp20/alpha crystallin family Complex1_LYR_2 PF13233.6 GAM36855.1 - 1.3e-06 29.0 0.2 2.5e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 Complex1_LYR-like ArsA_HSP20 PF17886.1 GAM36855.1 - 0.0029 17.1 0.0 3.2 7.4 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Hid1 PF12722.7 GAM36856.1 - 1.5 6.8 3.4 0.39 8.8 0.3 1.6 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Autophagy_act_C PF03987.15 GAM36857.1 - 6.1e-13 49.1 0.1 9.7e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain S-layer PF07752.11 GAM36857.1 - 0.087 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 S-layer protein RRM_1 PF00076.22 GAM36858.1 - 7.7e-10 38.5 0.0 1.9e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM36858.1 - 5.1e-05 22.9 0.0 6.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM36858.1 - 0.0078 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif WD40 PF00400.32 GAM36859.1 - 1.4e-17 63.7 11.8 0.00018 22.2 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM36859.1 - 4.6e-09 36.4 0.0 0.0069 16.7 0.0 4.8 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3642 PF12182.8 GAM36859.1 - 0.011 16.0 0.1 0.63 10.4 0.1 2.5 2 0 0 2 2 2 0 Bacterial lipoprotein Ge1_WD40 PF16529.5 GAM36859.1 - 0.029 13.3 0.1 4.5 6.1 0.0 2.9 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 GAM36859.1 - 0.034 12.9 1.3 7.5 5.2 0.0 3.5 2 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Lipase_3 PF01764.25 GAM36860.1 - 2.6e-29 101.9 0.0 3.9e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 GAM36860.1 - 0.00012 21.4 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM36860.1 - 0.00017 22.2 0.0 0.00024 21.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAM36860.1 - 0.0091 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 GAM36860.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 GAM36860.1 - 0.036 14.2 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.8 GAM36860.1 - 0.041 13.5 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Esterase PF00756.20 GAM36860.1 - 0.044 13.4 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Putative esterase DUF676 PF05057.14 GAM36860.1 - 0.052 13.1 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Fungal_trans_2 PF11951.8 GAM36861.1 - 2.2e-15 56.4 6.1 3.9e-15 55.6 6.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain WW PF00397.26 GAM36861.1 - 5.8e-11 42.3 0.4 1.3e-10 41.2 0.4 1.6 1 0 0 1 1 1 1 WW domain Zn_clus PF00172.18 GAM36861.1 - 1.8e-09 37.5 8.5 3.2e-09 36.8 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhoD PF09423.10 GAM36861.1 - 0.054 12.5 0.2 0.1 11.6 0.2 1.3 1 0 0 1 1 1 0 PhoD-like phosphatase Ecm29 PF13001.7 GAM36862.1 - 5.3e-159 530.1 3.4 3.8e-157 524.0 0.0 3.4 4 0 0 4 4 4 2 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 GAM36862.1 - 0.00036 21.1 0.6 2.2 8.9 0.2 5.0 5 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 GAM36862.1 - 0.005 17.0 3.4 3.8 8.0 0.1 7.3 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.6 GAM36862.1 - 0.0093 16.5 7.0 16 6.2 0.0 7.3 6 1 1 7 7 7 1 HEAT-like repeat Arm_2 PF04826.13 GAM36862.1 - 0.057 12.9 0.1 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 Armadillo-like DUF3385 PF11865.8 GAM36862.1 - 0.82 9.6 3.0 4.7 7.1 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) SNCAIP_SNCA_bd PF16700.5 GAM36862.1 - 5.1 6.9 6.0 18 5.2 0.1 3.8 4 0 0 4 4 4 0 Synphilin-1 alpha-Synuclein-binding domain PNGaseA PF12222.8 GAM36863.1 - 2.7e-185 616.4 1.1 3.8e-185 615.9 1.1 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A SNF2_N PF00176.23 GAM36863.1 - 2.1e-59 201.0 0.0 3.6e-59 200.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 GAM36863.1 - 6.6e-09 35.5 9.4 1.5e-08 34.3 9.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM36863.1 - 8e-09 35.2 7.7 1.9e-08 34.0 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM36863.1 - 1.2e-08 34.7 9.5 2.6e-08 33.6 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM36863.1 - 1.1e-06 28.9 10.8 2.4e-06 27.8 10.8 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 GAM36863.1 - 2.4e-06 27.3 7.7 5.8e-06 26.1 7.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Helicase_C PF00271.31 GAM36863.1 - 5.4e-06 26.7 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 GAM36863.1 - 7.4e-06 25.9 6.0 1.7e-05 24.7 6.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAM36863.1 - 0.00023 21.4 8.4 0.00063 20.0 8.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAM36863.1 - 0.002 18.1 9.1 0.0046 16.9 9.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 GAM36863.1 - 0.0034 17.4 0.0 0.0094 16.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 GAM36863.1 - 0.0054 16.9 7.9 0.011 15.9 7.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 GAM36863.1 - 0.018 15.0 0.4 0.042 13.8 0.4 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Phage_HK97_TLTM PF06120.11 GAM36863.1 - 0.027 13.7 0.1 0.027 13.7 0.1 2.4 2 1 1 3 3 3 0 Tail length tape measure protein Zn_ribbon_17 PF17120.5 GAM36863.1 - 0.7 9.6 7.5 1.5 8.5 7.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 GAM36863.1 - 1.4 8.8 8.0 3.4 7.5 8.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Aldo_ket_red PF00248.21 GAM36864.1 - 3e-65 220.3 0.0 3.9e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3425 PF11905.8 GAM36864.1 - 7.2e-18 64.8 0.0 1.7e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) PMM PF03332.13 GAM36865.1 - 9.6e-103 342.7 0.1 1.3e-102 342.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase DnaJ PF00226.31 GAM36865.1 - 1.4e-20 73.2 0.7 2.9e-20 72.1 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain TMPIT PF07851.13 GAM36865.1 - 0.065 12.5 0.1 0.095 11.9 0.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF456 PF04306.13 GAM36865.1 - 0.1 12.9 1.2 0.17 12.1 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.6 GAM36865.1 - 0.36 10.9 10.1 0.79 9.8 10.1 1.6 1 0 0 1 1 1 0 Glycine zipper Bacteriocin_IIc PF10439.9 GAM36865.1 - 0.39 10.9 6.6 0.82 9.8 6.6 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide RRM_1 PF00076.22 GAM36866.1 - 4.6e-53 176.9 0.1 9.3e-18 63.8 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM36866.1 - 1.2e-37 127.6 0.0 2.4e-28 97.8 0.0 4.4 4 0 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 GAM36866.1 - 3.5e-08 33.3 0.0 0.0034 17.4 0.0 3.7 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 GAM36866.1 - 0.0031 17.5 5.1 0.27 11.3 0.0 4.3 4 1 1 5 5 5 1 RNA binding motif RRM_7 PF16367.5 GAM36866.1 - 0.051 13.7 0.0 15 5.8 0.0 3.3 3 0 0 3 3 3 0 RNA recognition motif MnmE_helical PF12631.7 GAM36866.1 - 0.39 10.8 2.4 1 9.5 2.4 1.8 1 1 0 1 1 1 0 MnmE helical domain ABC2_membrane PF01061.24 GAM36869.1 - 0.0062 16.0 2.7 0.0062 16.0 2.7 2.1 2 0 0 2 2 2 1 ABC-2 type transporter Claudin_3 PF06653.11 GAM36869.1 - 0.12 12.3 10.5 0.35 10.8 10.4 1.7 1 1 0 1 1 1 0 Tight junction protein, Claudin-like TMEM223 PF14640.6 GAM36869.1 - 0.23 11.6 0.7 0.77 9.9 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 223 STE2 PF02116.15 GAM36869.1 - 0.46 9.7 7.7 0.18 11.1 2.7 2.0 1 1 1 2 2 2 0 Fungal pheromone mating factor STE2 GPCR C2 PF00168.30 GAM36871.1 - 1.2e-14 54.4 0.0 2.3e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain Ank_2 PF12796.7 GAM36872.1 - 3.1e-05 24.5 0.0 0.012 16.2 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM36872.1 - 4e-05 24.1 0.0 0.031 14.9 0.0 4.2 3 1 0 3 3 3 1 Ankyrin repeats (many copies) NACHT PF05729.12 GAM36872.1 - 5.1e-05 23.3 0.2 0.00015 21.7 0.1 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 GAM36872.1 - 0.00054 20.4 0.1 0.0016 18.9 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM36872.1 - 0.0012 19.1 0.0 0.0097 16.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain Ank_3 PF13606.6 GAM36872.1 - 0.0015 18.9 0.0 1.2 9.9 0.0 5.1 6 0 0 6 6 5 1 Ankyrin repeat ATPase PF06745.13 GAM36872.1 - 0.0081 15.5 0.4 0.1 12.0 0.1 2.3 1 1 1 2 2 2 1 KaiC Ank PF00023.30 GAM36872.1 - 0.0082 16.6 0.0 0.045 14.2 0.0 2.4 1 0 0 1 1 1 1 Ankyrin repeat AAA PF00004.29 GAM36872.1 - 0.0084 16.5 0.1 0.021 15.2 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CASP_C PF08172.12 GAM36872.1 - 0.02 14.3 0.2 0.042 13.2 0.2 1.4 1 0 0 1 1 1 0 CASP C terminal Goodbye PF17109.5 GAM36872.1 - 0.027 14.9 0.8 0.23 11.9 0.0 2.6 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Ank_5 PF13857.6 GAM36872.1 - 0.047 14.0 0.1 2.6 8.5 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) AAA_30 PF13604.6 GAM36872.1 - 0.22 11.2 0.0 0.45 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Spore_YunB PF09560.10 GAM36873.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein YunB (Spo_YunB) UTP15_C PF09384.10 GAM36874.1 - 1.6e-53 180.3 0.1 4.1e-53 179.0 0.4 1.5 2 0 0 2 2 2 1 UTP15 C terminal WD40 PF00400.32 GAM36874.1 - 2.6e-19 69.2 1.5 0.00072 20.3 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM36874.1 - 3.9e-09 36.7 0.0 0.0033 17.7 0.0 4.4 5 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 GAM36874.1 - 8.7e-05 21.9 0.2 0.2 10.9 0.1 2.3 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_2 PF13360.6 GAM36874.1 - 0.006 16.2 0.4 0.078 12.5 0.2 2.3 1 1 1 2 2 2 1 PQQ-like domain CPSF_A PF03178.15 GAM36874.1 - 0.016 14.6 0.0 0.062 12.6 0.0 1.7 1 1 1 2 2 2 0 CPSF A subunit region Nbas_N PF15492.6 GAM36874.1 - 0.13 11.6 0.0 0.3 10.4 0.0 1.6 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal ATP-synt_E PF05680.12 GAM36874.1 - 0.24 11.7 1.4 0.52 10.7 1.4 1.6 1 0 0 1 1 1 0 ATP synthase E chain Fungal_trans PF04082.18 GAM36875.1 - 1.6e-26 92.9 0.1 3.2e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM36875.1 - 4.7e-06 26.6 10.1 1.1e-05 25.5 10.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAPG_hydrolase PF18089.1 GAM36875.1 - 0.053 13.1 0.1 0.17 11.4 0.0 1.8 2 1 1 3 3 3 0 DAPG hydrolase PhiG domain PhyH PF05721.13 GAM36877.1 - 8.1e-44 150.4 0.0 1.1e-43 150.0 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 GAM36877.1 - 0.019 15.4 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase NAM-associated PF14303.6 GAM36878.1 - 0.11 13.3 4.0 0.14 12.9 4.0 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain MFS_MOT1 PF16983.5 GAM36879.1 - 2.3e-63 211.5 35.0 6.5e-34 116.7 10.8 3.2 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 GAM36879.1 - 0.00018 20.4 27.5 0.048 12.4 27.0 3.3 1 1 1 2 2 2 1 Sulfate permease family Sulf_transp PF04143.14 GAM36880.1 - 4e-05 23.3 13.6 0.0043 16.7 2.7 3.1 3 0 0 3 3 3 2 Sulphur transport Peptidase_M28 PF04389.17 GAM36881.1 - 4.3e-30 104.9 0.0 1.3e-29 103.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 BcrAD_BadFG PF01869.20 GAM36882.1 - 0.093 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family PA-IL PF07828.12 GAM36882.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 PA-IL-like protein tRNA-synt_1b PF00579.25 GAM36883.1 - 1.3e-74 251.2 0.0 2.5e-74 250.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MutS_V PF00488.21 GAM36883.1 - 8e-69 231.5 0.1 1.4e-68 230.6 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAM36883.1 - 2.4e-41 142.1 0.1 5.2e-41 141.0 0.1 1.6 1 0 0 1 1 1 1 MutS domain III TyrRSs_C PF16714.5 GAM36883.1 - 4.5e-41 139.4 0.0 9.5e-41 138.4 0.0 1.6 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain MutS_I PF01624.20 GAM36883.1 - 2.4e-33 114.7 0.1 7.2e-33 113.2 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 GAM36883.1 - 1.6e-13 51.1 0.0 4.1e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 GAM36883.1 - 9.6e-13 48.3 0.2 2e-12 47.3 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 GAM36883.1 - 0.015 15.8 1.7 0.039 14.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAM36883.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 GAM36883.1 - 0.07 12.9 0.2 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system tRNA-synt_2 PF00152.20 GAM36884.1 - 5.4e-90 301.6 0.0 1.1e-89 300.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) NACHT_N PF17100.5 GAM36884.1 - 4.1e-10 39.9 1.0 2.1e-09 37.6 1.0 2.2 1 1 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase tRNA_anti-codon PF01336.25 GAM36884.1 - 0.00017 21.5 0.0 0.00064 19.7 0.0 2.0 1 1 1 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.25 GAM36884.1 - 0.0041 17.1 0.0 0.0093 15.9 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Glyco_hydro_71 PF03659.14 GAM36885.1 - 1.1e-131 439.1 8.9 1.6e-131 438.6 8.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 CS PF04969.16 GAM36886.1 - 7.2e-16 59.0 0.0 1.4e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 CS domain Ribosomal_L14 PF00238.19 GAM36887.1 - 2.1e-34 118.2 0.0 2.5e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Endonuc-FokI_C PF09254.11 GAM36887.1 - 0.077 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Hist_deacetyl PF00850.19 GAM36888.1 - 1.1e-81 274.7 0.0 1.9e-81 273.9 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.21 GAM36889.1 - 9.5e-33 112.7 0.0 1.8e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 GAM36889.1 - 3.2e-12 46.9 0.7 5.1e-12 46.2 0.7 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 GAM36889.1 - 4.9e-07 29.5 0.0 9.5e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain NIF PF03031.18 GAM36890.1 - 1.3e-41 141.9 0.0 1.9e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Beta_elim_lyase PF01212.21 GAM36892.1 - 1.7e-68 231.0 0.0 2.5e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Fungal_trans PF04082.18 GAM36893.1 - 5.6e-15 55.1 0.0 1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM36893.1 - 1.4e-06 28.3 6.3 3.1e-06 27.2 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box PF00646.33 GAM36894.1 - 0.0021 17.9 0.0 0.0044 16.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAM36894.1 - 0.043 13.7 0.1 0.099 12.6 0.1 1.7 1 0 0 1 1 1 0 F-box-like GRDP-like PF07173.12 GAM36895.1 - 4.5e-17 63.0 7.3 4.7e-13 50.0 0.1 3.1 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like FAD_binding_7 PF03441.14 GAM36896.1 - 1.1e-76 256.8 0.7 1.1e-76 256.8 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GAM36896.1 - 2.2e-41 141.6 0.1 5.1e-41 140.4 0.1 1.6 1 0 0 1 1 1 1 DNA photolyase Fungal_trans PF04082.18 GAM36896.1 - 4.1e-08 32.6 0.4 7.4e-08 31.7 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM36896.1 - 9.5e-07 28.8 9.6 2.5e-06 27.5 9.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DivIC PF04977.15 GAM36896.1 - 0.1 12.4 0.8 0.24 11.2 0.3 1.9 2 0 0 2 2 2 0 Septum formation initiator MFS_1 PF07690.16 GAM36897.1 - 8.5e-30 103.9 30.8 2.2e-20 72.9 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM36897.1 - 8.6e-21 74.3 18.5 7.1e-20 71.3 18.5 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter NPV_P10 PF05531.12 GAM36898.1 - 2.6e-07 31.0 44.5 1.3 9.5 4.3 10.6 5 3 4 9 9 9 3 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 GAM36898.1 - 5.3e-05 23.4 42.5 0.00014 22.1 1.4 8.4 3 2 5 8 8 8 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 GAM36898.1 - 0.00039 20.4 44.0 2.5 8.2 0.2 8.9 5 2 3 9 9 9 3 Protein of unknown function (DUF1664) GAS PF13851.6 GAM36898.1 - 0.0011 18.4 4.3 0.0011 18.4 4.3 6.3 3 1 3 6 6 6 3 Growth-arrest specific micro-tubule binding HAP1_N PF04849.13 GAM36898.1 - 0.0011 18.3 14.2 0.0011 18.3 14.2 3.6 1 1 1 3 3 3 1 HAP1 N-terminal conserved region Spc7 PF08317.11 GAM36898.1 - 0.002 17.0 56.0 0.021 13.7 4.8 5.6 2 2 3 6 6 6 3 Spc7 kinetochore protein APG6_N PF17675.1 GAM36898.1 - 0.014 15.9 3.2 0.014 15.9 3.2 6.3 3 2 3 6 6 5 0 Apg6 coiled-coil region AAA_13 PF13166.6 GAM36898.1 - 0.027 13.1 49.5 0.056 12.1 13.3 4.1 2 2 1 3 3 3 0 AAA domain Nup54_C PF18437.1 GAM36898.1 - 0.036 14.0 4.6 1 9.3 1.0 3.4 2 1 0 2 2 2 0 Nup54 C-terminal interacting domain DUF948 PF06103.11 GAM36898.1 - 0.14 12.4 36.5 2.9 8.2 0.6 8.7 4 2 3 7 7 7 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 GAM36898.1 - 0.79 9.9 43.6 0.14 12.3 3.7 6.7 1 1 4 7 7 7 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 GAM36898.1 - 1.1 8.8 34.3 1.8e+04 -16.9 34.3 4.6 1 1 0 1 1 0 0 Exonuclease VII, large subunit BRE1 PF08647.11 GAM36898.1 - 1.6 8.9 0.0 1.6 8.9 0.0 8.3 5 3 3 9 9 9 0 BRE1 E3 ubiquitin ligase Fungal_TACC PF12709.7 GAM36898.1 - 1.8 9.1 0.0 1.8 9.1 0.0 6.4 7 3 1 8 8 7 0 Fungal Transforming acidic coiled-coil (TACC) proteins TRAF_BIRC3_bd PF16673.5 GAM36898.1 - 4.2 7.2 26.6 12 5.8 0.2 8.1 5 3 3 8 8 8 0 TNF receptor-associated factor BIRC3 binding domain DUF4407 PF14362.6 GAM36898.1 - 5.1 6.4 42.4 1.7e+03 -1.9 18.1 4.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) BORCS8 PF10167.9 GAM36898.1 - 7.8 6.5 15.0 0.62 10.0 0.1 5.2 5 1 1 6 6 6 0 BLOC-1-related complex sub-unit 8 AA_permease PF00324.21 GAM36899.1 - 1.5e-99 333.7 41.2 1.9e-99 333.4 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM36899.1 - 1.1e-18 67.3 41.8 1.6e-18 66.8 41.8 1.2 1 0 0 1 1 1 1 Amino acid permease TSR PF18487.1 GAM36899.1 - 0.24 11.6 0.3 0.49 10.6 0.3 1.4 1 0 0 1 1 1 0 Thrombospondin type 1 repeat Aldolase_II PF00596.21 GAM36900.1 - 1.8e-47 161.7 0.3 2.4e-47 161.3 0.3 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain p450 PF00067.22 GAM36901.1 - 7.1e-57 193.2 0.0 5.2e-56 190.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 GAM36902.1 - 8.5e-10 38.6 7.5 1.6e-09 37.7 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM36902.1 - 4.7e-07 29.1 0.2 1.4e-06 27.6 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Phosphodiest PF01663.22 GAM36903.1 - 1.3e-32 113.8 0.0 5.1e-32 111.8 0.0 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Pkinase PF00069.25 GAM36905.1 - 1.4e-72 244.2 0.0 2.4e-72 243.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM36905.1 - 6.5e-36 123.9 0.0 2e-35 122.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM36905.1 - 0.0026 17.1 1.3 3.8 6.7 0.0 3.1 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 GAM36905.1 - 0.053 13.4 1.3 2.4 8.0 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family HupH_C PF04809.13 GAM36905.1 - 0.089 12.5 0.1 0.59 9.8 0.0 2.3 3 0 0 3 3 3 0 HupH hydrogenase expression protein, C-terminal conserved region MFS_1 PF07690.16 GAM36907.1 - 3.7e-37 128.1 62.1 5e-35 121.1 44.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM36907.1 - 3.5e-08 32.8 39.2 1.9e-06 27.0 13.7 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter Phage_holin_3_6 PF07332.11 GAM36907.1 - 0.5 10.4 0.0 0.5 10.4 0.0 4.8 6 0 0 6 6 6 0 Putative Actinobacterial Holin-X, holin superfamily III F-box-like PF12937.7 GAM36908.1 - 0.00097 19.0 0.3 0.0087 15.9 0.0 2.5 2 1 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 GAM36908.1 - 0.0019 18.2 0.0 0.0049 16.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.33 GAM36908.1 - 0.61 10.0 4.3 4 7.4 0.5 2.5 2 0 0 2 2 2 0 F-box domain MFS_1 PF07690.16 GAM36909.1 - 2.4e-33 115.6 37.0 1.5e-22 80.0 25.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM36909.1 - 2e-11 43.0 23.6 1.9e-10 39.8 18.0 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM36909.1 - 5.8e-05 22.1 30.3 0.0077 15.1 5.3 4.0 2 1 2 4 4 4 3 Sugar (and other) transporter HAMP PF00672.25 GAM36910.1 - 5.9e-43 145.0 15.4 7.2e-09 35.9 0.0 7.5 6 2 1 7 7 7 5 HAMP domain HATPase_c PF02518.26 GAM36910.1 - 2.9e-33 114.7 0.4 2.2e-32 111.9 0.1 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM36910.1 - 2.1e-25 89.1 1.1 7.9e-25 87.2 0.6 2.3 2 0 0 2 2 1 1 Response regulator receiver domain HisKA PF00512.25 GAM36910.1 - 4.2e-16 58.7 5.0 4.8e-16 58.5 0.1 3.9 5 0 0 5 5 3 1 His Kinase A (phospho-acceptor) domain APG17 PF04108.12 GAM36910.1 - 1.5e-11 44.0 7.2 0.0017 17.5 0.0 5.5 1 1 2 3 3 3 3 Autophagy protein Apg17 Syntaxin_2 PF14523.6 GAM36910.1 - 5.3e-07 29.9 14.5 0.73 10.2 0.0 6.6 3 2 1 6 6 5 2 Syntaxin-like protein DUF4279 PF14106.6 GAM36910.1 - 4.5e-05 23.6 0.0 13 6.0 0.0 5.5 5 1 0 5 5 5 0 Domain of unknown function (DUF4279) DUF948 PF06103.11 GAM36910.1 - 0.00084 19.6 53.6 1.5 9.1 0.2 9.9 4 2 3 7 7 7 2 Bacterial protein of unknown function (DUF948) WXG100 PF06013.12 GAM36910.1 - 0.0026 17.9 25.0 3.1 8.1 0.7 8.1 7 1 0 7 7 7 1 Proteins of 100 residues with WXG Baculo_PEP_C PF04513.12 GAM36910.1 - 0.0035 17.4 5.3 0.0035 17.4 5.3 6.8 1 1 3 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1843 PF08898.10 GAM36910.1 - 0.012 16.1 5.0 27 5.4 0.0 5.9 5 1 0 5 5 5 0 Domain of unknown function (DUF1843) Gp-FAR-1 PF05823.12 GAM36910.1 - 0.026 14.9 5.1 43 4.4 0.1 4.9 1 1 3 5 5 5 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Fib_alpha PF08702.10 GAM36910.1 - 0.027 14.7 31.4 0.86 9.8 0.7 7.2 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family DUF3829 PF12889.7 GAM36910.1 - 0.035 13.6 16.0 0.17 11.3 0.6 5.1 4 2 3 7 7 6 0 Protein of unknown function (DUF3829) NOD PF06816.13 GAM36910.1 - 0.042 13.5 0.0 6.2 6.5 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein DUF4795 PF16043.5 GAM36910.1 - 0.044 13.4 23.9 2.7e+02 1.0 2.5 4.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) CENP-B_dimeris PF09026.10 GAM36910.1 - 0.051 14.0 13.5 0.17 12.3 13.5 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain IcmF_C PF06744.12 GAM36910.1 - 0.078 12.6 0.1 0.28 10.8 0.1 1.9 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal PA-IL PF07828.12 GAM36910.1 - 0.087 12.8 2.5 2.1 8.4 0.1 2.9 2 0 0 2 2 2 0 PA-IL-like protein CMD PF02627.20 GAM36910.1 - 0.097 12.7 0.3 13 6.0 0.0 3.6 4 0 0 4 4 3 0 Carboxymuconolactone decarboxylase family GLE1 PF07817.13 GAM36910.1 - 0.92 8.7 11.1 18 4.4 0.0 4.5 2 1 3 5 5 5 0 GLE1-like protein DUF2457 PF10446.9 GAM36910.1 - 0.98 8.5 18.5 1.7 7.7 18.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1759 PF03564.15 GAM36910.1 - 1.1 9.2 6.7 26 4.7 0.0 4.8 4 1 0 5 5 4 0 Protein of unknown function (DUF1759) DNA_pol_phi PF04931.13 GAM36910.1 - 1.3 7.0 19.0 0.2 9.7 15.0 1.6 2 0 0 2 2 2 0 DNA polymerase phi PPP4R2 PF09184.11 GAM36910.1 - 1.3 8.5 10.1 3.9 7.0 10.1 1.8 1 0 0 1 1 1 0 PPP4R2 CENP-F_leu_zip PF10473.9 GAM36910.1 - 1.4 8.9 32.2 0.67 10.0 0.1 7.9 7 2 1 8 8 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BORCS6 PF10157.9 GAM36910.1 - 1.8 8.8 14.1 6.3 7.0 0.1 5.3 3 2 2 5 5 5 0 BLOC-1-related complex sub-unit 6 Mer2 PF09074.10 GAM36910.1 - 2.5 7.9 35.7 2.2 8.0 0.5 6.2 4 1 1 5 5 5 0 Mer2 DUF5593 PF18007.1 GAM36910.1 - 2.9 8.6 9.1 57 4.5 0.1 5.0 4 1 0 4 4 4 0 Domain of unknown function (DUF5593) SpoIIID PF12116.8 GAM36910.1 - 5.1 7.3 12.6 39 4.4 0.2 5.9 6 1 1 7 7 5 0 Stage III sporulation protein D Phage_Mu_Gam PF07352.12 GAM36910.1 - 7.9 6.4 14.6 17 5.3 0.2 5.5 4 1 1 6 6 6 0 Bacteriophage Mu Gam like protein RXT2_N PF08595.11 GAM36910.1 - 8.6 6.4 11.6 29 4.7 11.6 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal tRNA-synt_2d PF01409.20 GAM36911.1 - 1.7e-87 293.0 0.0 2.2e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 GAM36911.1 - 5.7e-16 58.5 0.2 1.7e-15 57.1 0.2 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 GAM36911.1 - 2e-07 30.7 0.0 0.0014 18.1 0.0 2.6 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 GAM36911.1 - 5.2e-05 22.5 0.1 0.0031 16.6 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 GAM36911.1 - 0.00012 21.9 0.5 0.00038 20.4 0.5 1.9 1 0 0 1 1 1 1 PheRS DNA binding domain 2 Ribosomal_S21e PF01249.18 GAM36912.1 - 2.7e-40 136.4 0.0 3e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.28 GAM36913.1 - 1.5e-06 28.2 0.0 3.6e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain IMPDH PF00478.25 GAM36914.1 - 3e-129 431.0 3.1 3.4e-129 430.8 3.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 GAM36914.1 - 8.4e-19 67.8 0.1 4.9e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 GAM36914.1 - 8.9e-08 31.5 0.6 6.7e-07 28.6 0.5 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 GAM36914.1 - 1.8e-05 24.3 6.9 0.019 14.4 6.0 2.7 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 GAM36914.1 - 0.00042 19.9 1.7 0.0019 17.7 1.7 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.19 GAM36914.1 - 0.0068 15.9 0.8 0.026 13.9 0.1 2.1 2 0 0 2 2 2 1 KDPG and KHG aldolase PK PF00224.21 GAM36914.1 - 0.035 13.0 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain ThiG PF05690.14 GAM36914.1 - 0.083 12.2 0.9 0.18 11.1 0.6 1.6 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG YpsA PF06908.11 GAM36914.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family Ank_2 PF12796.7 GAM36915.1 - 3.1e-31 107.8 3.7 3.7e-10 40.3 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM36915.1 - 1.4e-24 86.1 2.5 8.9e-09 35.7 0.0 6.6 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM36915.1 - 2.4e-22 78.7 3.6 4.2e-06 26.9 0.0 7.2 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM36915.1 - 3e-19 67.1 6.2 0.0019 18.6 0.0 9.5 10 0 0 10 10 10 4 Ankyrin repeat Ank PF00023.30 GAM36915.1 - 9e-12 44.9 7.4 0.0018 18.7 0.0 6.2 7 0 0 7 7 7 3 Ankyrin repeat Glyco_transf_20 PF00982.21 GAM36915.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 20 adh_short_C2 PF13561.6 GAM36916.1 - 5.2e-54 183.3 0.0 7e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM36916.1 - 1e-45 155.6 0.2 1.2e-45 155.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM36916.1 - 4e-10 39.9 0.1 5.2e-10 39.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM36916.1 - 0.0014 18.1 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 GAM36916.1 - 0.0063 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 GAM36916.1 - 0.025 14.0 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 GAM36916.1 - 0.066 12.6 0.0 0.094 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.8 GAM36916.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF952 PF06108.12 GAM36917.1 - 9.5e-21 73.6 0.0 1.2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) RasGAP_C PF03836.15 GAM36918.1 - 5.8e-48 162.5 5.5 5.8e-48 162.5 5.5 2.8 3 0 0 3 3 3 1 RasGAP C-terminus RasGAP PF00616.19 GAM36918.1 - 2.9e-44 151.3 0.6 6.6e-44 150.1 0.1 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 GAM36918.1 - 1.3e-12 47.8 0.0 4.4e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 GAM36918.1 - 6.3e-10 38.0 42.3 0.81 9.6 0.1 14.1 16 0 0 16 16 16 5 IQ calmodulin-binding motif CAMSAP_CH PF11971.8 GAM36918.1 - 0.0077 16.1 0.1 0.03 14.1 0.0 2.0 2 0 0 2 2 2 1 CAMSAP CH domain Prefoldin_2 PF01920.20 GAM36918.1 - 3 7.8 16.5 21 5.1 0.0 5.7 5 0 0 5 5 5 0 Prefoldin subunit ENTH PF01417.20 GAM36919.1 - 9.4e-46 154.9 0.2 1.3e-45 154.5 0.2 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 GAM36919.1 - 2.9e-05 23.2 0.0 4e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 ANTH domain DUF5102 PF17104.5 GAM36919.1 - 1.4 8.9 6.0 3.3 7.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) GIT_SHD PF08518.11 GAM36920.1 - 1e-24 85.8 5.8 2e-13 49.7 0.6 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 GAM36920.1 - 0.0007 19.7 0.1 0.0007 19.7 0.1 3.7 3 1 0 4 4 4 1 G protein-coupled receptor kinase-interacting protein 1 C term APG6_N PF17675.1 GAM36920.1 - 0.0033 17.9 16.4 0.0033 17.9 16.4 3.2 2 1 1 3 3 3 1 Apg6 coiled-coil region Taxilin PF09728.9 GAM36920.1 - 0.03 13.5 36.7 0.32 10.1 15.6 2.4 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF641 PF04859.12 GAM36920.1 - 0.034 14.5 0.9 0.034 14.5 0.9 3.6 3 1 0 4 4 4 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 GAM36920.1 - 0.18 11.1 26.5 0.13 11.5 22.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Lebercilin PF15619.6 GAM36920.1 - 0.24 11.1 29.3 0.83 9.3 8.3 2.8 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ERM PF00769.19 GAM36920.1 - 0.31 10.8 40.7 0.019 14.8 25.1 3.2 2 1 0 3 3 3 0 Ezrin/radixin/moesin family Fmp27_WPPW PF10359.9 GAM36920.1 - 0.33 9.8 26.5 12 4.6 26.5 2.2 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF948 PF06103.11 GAM36920.1 - 1.9 8.8 10.8 0.22 11.8 0.3 4.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) XLF PF09302.11 GAM36920.1 - 8.6 6.5 13.3 0.19 11.9 1.9 3.0 1 1 1 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component SNF2_N PF00176.23 GAM36921.1 - 7e-52 176.3 0.1 1.1e-51 175.7 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 GAM36921.1 - 1.1e-24 86.3 0.3 3.2e-24 84.8 0.3 1.9 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 GAM36921.1 - 6e-21 74.9 0.0 2.9e-18 66.2 0.0 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM36921.1 - 7.3e-07 29.3 0.1 3.3e-06 27.2 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAM36921.1 - 1.3e-06 27.9 0.0 2.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 GAM36921.1 - 0.00077 19.3 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 GAM36921.1 - 0.016 14.4 0.3 0.48 9.5 0.0 2.5 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 RNase_PH PF01138.21 GAM36922.1 - 5.3e-35 120.8 0.5 1.1e-34 119.8 0.5 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Pro_isomerase PF00160.21 GAM36923.1 - 1.6e-46 158.5 0.3 1.9e-46 158.3 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SH3_1 PF00018.28 GAM36924.1 - 2.5e-11 43.0 0.0 4e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAM36924.1 - 4e-09 36.2 0.0 8.7e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAM36924.1 - 2.4e-07 30.3 0.0 5.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PolyA_pol PF01743.20 GAM36925.1 - 1e-21 77.7 0.3 8.1e-12 45.7 0.3 2.6 1 1 0 2 2 2 2 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 GAM36925.1 - 0.00019 21.1 0.1 0.0018 18.0 0.0 2.3 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A HMG-CoA_red PF00368.18 GAM36927.1 - 2.4e-139 464.4 9.0 3.2e-139 464.0 9.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 GAM36927.1 - 1.1e-45 155.3 0.0 2.2e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 GAM36927.1 - 2.3e-14 53.5 4.5 6.4e-14 52.1 4.5 1.8 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 GAM36927.1 - 4.9e-10 38.2 0.3 4.9e-10 38.2 0.3 1.4 2 0 0 2 2 2 1 Patched family YMF19 PF02326.15 GAM36927.1 - 0.34 11.7 1.2 1.3 9.8 0.0 2.5 3 0 0 3 3 3 0 Plant ATP synthase F0 Acyl-CoA_dh_1 PF00441.24 GAM36928.1 - 1.7e-17 64.0 0.1 5.8e-17 62.3 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 GAM36928.1 - 1.4e-13 51.1 0.0 2.6e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 GAM36928.1 - 1.4e-10 41.2 0.0 2.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAM36928.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Ssu72 PF04722.13 GAM36929.1 - 1.4e-81 272.6 0.0 1.7e-81 272.4 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein Isochorismatase PF00857.20 GAM36930.1 - 2.2e-18 67.1 0.0 3.2e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family rve PF00665.26 GAM36930.1 - 0.14 12.3 0.1 0.23 11.7 0.1 1.3 1 0 0 1 1 1 0 Integrase core domain DUF3605 PF12239.8 GAM36931.1 - 2.5e-56 190.3 0.4 3.1e-56 189.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Clathrin_lg_ch PF01086.17 GAM36931.1 - 0.19 11.8 0.0 0.3 11.1 0.0 1.2 1 0 0 1 1 1 0 Clathrin light chain Oxysterol_BP PF01237.18 GAM36932.1 - 6.9e-91 304.9 0.1 5e-81 272.4 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein Hist_deacetyl PF00850.19 GAM36933.1 - 4.3e-77 259.6 0.0 6.5e-77 259.0 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Sugar_tr PF00083.24 GAM36936.1 - 5.9e-73 246.3 21.8 1.4e-54 185.7 13.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM36936.1 - 5.6e-15 55.1 20.9 4.1e-14 52.3 21.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM36936.1 - 0.0022 16.5 3.8 0.0022 16.5 3.8 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1304 PF06993.12 GAM36936.1 - 0.011 15.7 2.7 0.055 13.5 2.7 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) Glyco_hydro_43 PF04616.14 GAM36937.1 - 2e-11 43.7 3.0 2e-11 43.7 3.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.18 GAM36938.1 - 4e-13 49.0 0.4 4e-13 49.0 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sulfatase PF00884.23 GAM36939.1 - 2.3e-50 171.7 0.0 5.7e-48 163.9 0.0 2.5 2 1 0 2 2 2 1 Sulfatase DUF4976 PF16347.5 GAM36939.1 - 8.7e-06 25.9 0.3 3.7e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 GAM36939.1 - 0.0042 16.7 0.2 0.064 12.8 0.0 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 GAM36939.1 - 0.083 13.6 0.0 0.63 10.8 0.0 2.2 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Peptidase_M20 PF01546.28 GAM36941.1 - 7.3e-22 78.1 0.0 1.1e-21 77.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM36941.1 - 2.2e-13 50.1 0.0 6.4e-13 48.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain TPR_10 PF13374.6 GAM36942.1 - 5.9e-23 80.0 0.0 1.4e-10 40.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM36942.1 - 7.9e-23 80.5 0.3 8.2e-12 45.3 0.2 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM36942.1 - 1.8e-05 24.4 0.3 0.0024 17.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat NACHT PF05729.12 GAM36942.1 - 5.5e-05 23.1 0.0 0.00014 21.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 GAM36942.1 - 0.00037 19.8 0.0 0.61 9.2 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_2 PF07719.17 GAM36942.1 - 0.0025 17.8 0.2 0.45 10.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAM36942.1 - 0.033 14.8 0.1 6.1 7.8 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_22 PF13401.6 GAM36942.1 - 0.047 14.0 0.0 0.24 11.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAM36942.1 - 0.092 12.3 0.1 0.44 10.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain TPR_14 PF13428.6 GAM36942.1 - 0.14 13.0 0.5 96 4.2 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 GAM36942.1 - 0.2 12.0 5.5 0.22 11.9 0.5 3.5 3 1 0 3 3 2 0 AAA ATPase domain TRAF6_Z2 PF18048.1 GAM36942.1 - 0.29 11.2 3.8 0.98 9.6 3.8 1.9 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 zf-Di19 PF05605.12 GAM36942.1 - 0.95 9.8 15.1 0.15 12.4 0.4 3.5 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Peptidase_S8 PF00082.22 GAM36943.1 - 2.3e-20 73.0 0.1 4.8e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 Subtilase family Zn_clus PF00172.18 GAM36943.1 - 0.0058 16.7 8.9 0.018 15.1 8.9 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 GAM36945.1 - 5.5e-63 213.3 0.0 6.9e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.6 GAM36946.1 - 3.4e-19 69.4 0.0 4.8e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM36946.1 - 0.0013 18.2 0.0 0.0024 17.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAM36946.1 - 0.14 11.2 0.1 0.38 9.8 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain MIOX PF05153.15 GAM36949.1 - 1e-123 411.8 1.1 1.3e-123 411.5 1.1 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase UBD PF16455.5 GAM36949.1 - 0.026 14.7 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-binding domain HD PF01966.22 GAM36949.1 - 0.043 14.0 0.2 0.99 9.6 0.1 2.5 1 1 0 1 1 1 0 HD domain DUF1796 PF08795.10 GAM36949.1 - 0.11 12.5 0.4 0.2 11.6 0.4 1.4 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) PA28_alpha PF02251.18 GAM36949.1 - 0.25 11.4 0.6 0.55 10.3 0.1 1.8 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit Aldo_ket_red PF00248.21 GAM36950.1 - 1.4e-35 123.0 0.0 2.9e-33 115.3 0.0 2.4 1 1 0 1 1 1 1 Aldo/keto reductase family SET PF00856.28 GAM36951.1 - 1.1e-15 58.4 0.1 9.1e-15 55.5 0.1 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.12 GAM36951.1 - 0.096 13.3 0.0 7.2 7.3 0.1 2.5 2 0 0 2 2 2 0 SAF domain GFO_IDH_MocA PF01408.22 GAM36952.1 - 2e-22 80.3 0.1 4.4e-22 79.1 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAM36952.1 - 0.0029 17.6 0.0 0.0079 16.2 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 GAM36952.1 - 0.012 16.1 0.1 0.11 13.1 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Toxin_R_bind_C PF07951.12 GAM36952.1 - 0.028 14.1 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding NAD_binding_2 PF03446.15 GAM36952.1 - 0.081 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 GAM36953.1 - 2.4e-15 56.7 0.0 3.6e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM36953.1 - 1.1e-12 47.5 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAM36953.1 - 3.6e-10 39.4 0.1 8.3e-09 35.0 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 GAM36953.1 - 7.6e-08 32.1 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAM36953.1 - 8.4e-07 29.0 0.0 1.7e-06 28.0 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 GAM36953.1 - 0.00092 19.2 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 GAM36953.1 - 0.0054 16.3 0.1 0.12 11.9 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 GAM36953.1 - 0.028 13.9 0.0 0.051 13.0 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.24 GAM36953.1 - 0.099 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAM36953.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Mit_ribos_Mrp51 PF11709.8 GAM36954.1 - 5.7e-111 371.6 1.0 6.6e-111 371.4 1.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.18 GAM36955.1 - 6.3e-60 200.5 0.8 7.7e-60 200.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal S17 RPAP2_Rtr1 PF04181.13 GAM36956.1 - 2.5e-22 79.0 0.0 5.2e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_1 PF00018.28 GAM36957.1 - 2e-11 43.3 0.1 6.7e-11 41.6 0.1 2.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAM36957.1 - 7.6e-09 35.3 0.1 1.7e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAM36957.1 - 1.2e-08 34.4 0.0 2.6e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.16 GAM36958.1 - 1.6e-50 172.1 23.0 1.6e-50 172.1 23.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM36958.1 - 5.7e-07 28.8 11.7 5.7e-07 28.8 11.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAM36958.1 - 0.00032 19.3 6.0 0.00066 18.2 6.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CPP1-like PF11833.8 GAM36958.1 - 0.15 11.7 4.8 0.46 10.1 4.8 1.8 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF1077 PF06417.12 GAM36959.1 - 1.4e-48 163.8 3.7 1.7e-48 163.5 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.20 GAM36960.1 - 2.9e-114 382.5 6.7 3.7e-114 382.2 6.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAM36960.1 - 4.6e-56 189.3 4.9 8.6e-55 185.2 0.6 3.3 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM36960.1 - 2.4e-12 47.1 4.6 0.0035 17.7 0.0 4.9 4 2 2 6 6 6 4 HEAT repeats HEAT PF02985.22 GAM36960.1 - 7.7e-08 32.0 4.4 0.14 12.4 0.1 5.5 7 0 0 7 7 7 3 HEAT repeat Atx10homo_assoc PF09759.9 GAM36960.1 - 0.00016 21.6 0.0 2.9 8.0 0.0 4.4 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 GAM36960.1 - 0.0043 17.1 1.3 1.3 9.1 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 GAM36960.1 - 0.021 14.6 2.0 3.4 7.4 0.1 3.0 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.6 GAM36960.1 - 0.028 14.9 4.6 38 4.9 0.0 5.5 6 1 0 6 6 6 0 HEAT-like repeat T_hemolysin PF12261.8 GAM36960.1 - 0.05 13.4 0.0 0.92 9.2 0.0 2.2 2 0 0 2 2 2 0 Thermostable hemolysin Aminotran_5 PF00266.19 GAM36961.1 - 7.5e-08 31.7 0.1 8.7e-07 28.2 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAM36961.1 - 0.049 12.9 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 GAM36961.1 - 0.061 11.8 0.0 0.09 11.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Isochorismatase PF00857.20 GAM36962.1 - 6e-31 108.0 0.0 7.1e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family GrpB PF04229.14 GAM36963.1 - 6.7e-51 172.7 0.0 7.8e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Ank_2 PF12796.7 GAM36964.1 - 4.7e-46 155.3 0.1 4.2e-10 40.1 0.0 7.0 3 1 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM36964.1 - 1.8e-39 133.6 3.1 2.2e-06 28.1 0.0 10.4 5 3 4 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM36964.1 - 2.6e-35 120.0 2.8 6.5e-07 29.5 0.0 9.0 4 3 6 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM36964.1 - 2.2e-31 104.3 0.9 0.00073 19.8 0.0 12.3 12 0 0 12 12 12 7 Ankyrin repeat Ank PF00023.30 GAM36964.1 - 2e-27 94.4 0.5 0.00082 19.7 0.0 9.7 10 0 0 10 10 10 6 Ankyrin repeat SPRY PF00622.28 GAM36964.1 - 1.1e-21 77.1 0.1 3.8e-21 75.4 0.0 2.0 2 0 0 2 2 2 1 SPRY domain NACHT PF05729.12 GAM36964.1 - 4.9e-11 42.8 0.0 1.4e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAM36964.1 - 0.00018 22.0 0.3 0.00099 19.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAM36964.1 - 0.00028 21.2 0.0 0.00097 19.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain MRJP PF03022.16 GAM36965.1 - 1.6e-08 34.3 0.0 2.4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 GAM36965.1 - 0.00039 20.1 0.7 0.077 12.6 0.0 2.9 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Glyco_hydro_115 PF15979.5 GAM36966.1 - 9.8e-129 429.6 0.1 1.4e-128 429.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 TRI12 PF06609.13 GAM36966.1 - 1.6e-22 79.7 5.7 2.4e-22 79.1 5.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) YrhK PF14145.6 GAM36966.1 - 0.2 11.6 3.3 2.7 7.9 0.1 2.7 2 0 0 2 2 2 0 YrhK-like protein Fungal_trans PF04082.18 GAM36967.1 - 1.6e-06 27.3 1.8 2.2e-06 26.9 0.6 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain A_thal_3526 PF09713.10 GAM36967.1 - 0.088 13.1 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) MFS_1 PF07690.16 GAM36968.1 - 0.00019 20.5 47.9 0.00025 20.1 45.7 2.2 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF1360 PF07098.11 GAM36968.1 - 0.016 15.2 1.0 0.016 15.2 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) Paf67 PF10255.9 GAM36969.1 - 4.9e-161 536.3 0.0 5.6e-161 536.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 GAM36969.1 - 0.027 14.5 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Paf1 PF03985.13 GAM36970.1 - 2e-50 172.1 0.0 3e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 Paf1 LON_substr_bdg PF02190.16 GAM36971.1 - 2.9e-20 73.0 0.0 5e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_3 PF13920.6 GAM36971.1 - 1.6e-10 40.6 9.5 2.9e-10 39.8 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM36971.1 - 1.5e-09 37.6 12.0 3.7e-09 36.3 10.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM36971.1 - 2.6e-07 30.4 11.2 6.3e-07 29.2 11.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM36971.1 - 5.5e-07 29.8 10.8 1.3e-06 28.6 10.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GAM36971.1 - 1.4e-05 24.9 10.1 2.8e-05 24.0 10.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAM36971.1 - 1.4e-05 24.8 10.1 3.3e-05 23.6 10.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAM36971.1 - 1.9e-05 24.5 6.3 1.9e-05 24.5 6.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 GAM36971.1 - 0.0046 16.7 12.7 0.0067 16.2 11.5 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 GAM36971.1 - 0.0073 16.6 4.8 0.021 15.1 4.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 GAM36971.1 - 0.02 15.1 8.1 0.035 14.3 8.1 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 GAM36971.1 - 0.025 14.8 16.4 0.036 14.2 13.7 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zinc_ribbon_2 PF13240.6 GAM36971.1 - 0.13 12.0 1.5 0.39 10.5 1.5 1.9 1 0 0 1 1 1 0 zinc-ribbon domain zf-P11 PF03854.14 GAM36971.1 - 0.29 10.8 7.9 0.57 9.9 7.9 1.5 1 0 0 1 1 1 0 P-11 zinc finger RICTOR_N PF14664.6 GAM36972.1 - 4.1e-128 427.5 0.4 4.1e-128 427.5 0.4 2.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 GAM36972.1 - 1.1e-38 131.9 0.1 2e-35 121.4 0.0 3.8 3 1 1 4 4 4 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 GAM36972.1 - 4.8e-37 125.9 2.1 4.1e-34 116.5 0.3 4.7 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 GAM36972.1 - 1.5e-27 95.6 3.6 2.2e-26 91.9 0.0 4.1 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 GAM36972.1 - 3e-16 59.3 8.9 7.1e-16 58.1 8.9 1.7 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.6 GAM36972.1 - 0.28 11.4 5.2 0.77 9.9 5.2 1.7 1 0 0 1 1 1 0 Up-regulated During Septation Uricase PF01014.18 GAM36973.1 - 1.9e-80 267.6 2.3 8.5e-43 145.8 0.9 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.19 GAM36973.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme DUF4993 PF16384.5 GAM36973.1 - 0.047 12.7 0.8 0.61 9.0 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function Ribosomal_L13 PF00572.18 GAM36974.1 - 3.6e-42 143.6 0.1 4.9e-42 143.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.19 GAM36975.1 - 1.7e-33 115.7 0.4 2e-33 115.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AAR2 PF05282.11 GAM36976.1 - 1.2e-100 337.4 0.0 1.3e-100 337.2 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein adh_short PF00106.25 GAM36977.1 - 4.3e-29 101.4 0.5 5.2e-29 101.1 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM36977.1 - 1.4e-22 80.4 0.5 2.6e-22 79.5 0.5 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM36977.1 - 3.6e-08 33.5 0.1 4.9e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM36977.1 - 0.0029 17.1 0.1 1.2 8.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAM36977.1 - 0.0051 16.9 0.4 0.0096 16.0 0.4 1.4 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 GAM36977.1 - 0.048 12.8 0.1 0.064 12.4 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GST_N PF02798.20 GAM36978.1 - 6e-14 52.2 0.0 1.6e-13 50.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAM36978.1 - 1.3e-13 51.2 0.0 2.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM36978.1 - 1.3e-11 44.6 0.0 2.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM36978.1 - 8.8e-09 35.5 0.0 1.7e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM36978.1 - 2.4e-07 30.9 0.0 3.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM36978.1 - 0.01 15.8 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosomal_S11 PF00411.19 GAM36980.1 - 3.7e-46 156.0 1.0 4.6e-46 155.7 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 GAM36980.1 - 0.068 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) PDH PF02153.17 GAM36981.1 - 1.1e-13 50.8 0.0 1.5e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase DUF3419 PF11899.8 GAM36983.1 - 1.5e-148 495.1 0.0 2.2e-148 494.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 GAM36983.1 - 1.4e-11 44.5 0.0 5.5e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM36983.1 - 2.3e-09 37.8 0.0 3e-08 34.3 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM36983.1 - 1.2e-08 35.5 0.0 8.2e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM36983.1 - 1.2e-07 31.7 0.0 4.7e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM36983.1 - 2.2e-07 30.4 0.0 7.5e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 GAM36983.1 - 5.3e-07 30.2 0.0 5.3e-06 27.0 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain PCMT PF01135.19 GAM36983.1 - 0.0033 17.2 0.0 0.0088 15.8 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 GAM36983.1 - 0.021 14.1 0.0 0.099 11.9 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_32 PF13679.6 GAM36983.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Arf PF00025.21 GAM36984.1 - 3.5e-73 244.8 0.1 4.3e-73 244.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAM36984.1 - 1.5e-13 51.0 0.0 2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAM36984.1 - 2.6e-11 43.3 0.0 3.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 GAM36984.1 - 3.2e-10 39.9 0.0 3.8e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GAM36984.1 - 2.9e-09 36.6 0.2 4.3e-05 22.8 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 GAM36984.1 - 6e-08 32.3 0.0 7.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM36984.1 - 5.4e-06 26.5 0.0 9.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM36984.1 - 0.00058 19.5 0.0 0.046 13.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAM36984.1 - 0.0089 15.6 0.6 0.039 13.5 0.6 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Actin PF00022.19 GAM36985.1 - 6.9e-29 100.7 0.0 3.3e-18 65.5 0.0 2.6 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 GAM36985.1 - 6.1e-07 28.6 0.0 0.001 17.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin_micro PF17003.5 GAM36985.1 - 0.00034 19.9 0.5 0.036 13.3 0.1 2.2 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 GAM36985.1 - 0.0078 16.6 0.0 0.04 14.3 0.0 2.3 1 1 0 1 1 1 1 Cell division protein FtsA DUF2114 PF09887.9 GAM36985.1 - 0.16 10.4 0.1 0.23 9.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Pex14_N PF04695.13 GAM36985.1 - 0.44 11.2 6.6 0.051 14.2 1.5 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4106 PF13388.6 GAM36985.1 - 1.8 7.7 8.5 3.3 6.9 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Rer1 PF03248.13 GAM36986.1 - 1.4e-80 269.1 6.3 1.6e-80 268.8 6.3 1.0 1 0 0 1 1 1 1 Rer1 family DUF4400 PF14348.6 GAM36986.1 - 1.9 8.0 8.0 0.2 11.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) ECH_1 PF00378.20 GAM36987.1 - 2.3e-77 259.7 0.0 2.6e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM36987.1 - 1.9e-37 129.5 0.2 1.2e-36 126.9 0.2 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 GAM36987.1 - 0.1 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 Chlorosome_CsmC PF11098.8 GAM36988.1 - 0.0024 17.8 9.6 0.003 17.6 9.6 1.0 1 0 0 1 1 1 1 Chlorosome envelope protein C SBP_bac_10 PF07596.11 GAM36988.1 - 0.12 12.3 3.5 0.15 12.0 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1559) Senescence PF06911.12 GAM36988.1 - 0.59 10.4 9.5 0.88 9.9 1.1 2.2 1 1 1 2 2 2 0 Senescence-associated protein Catalase PF00199.19 GAM36989.1 - 5.1e-195 648.0 0.2 6.6e-195 647.6 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 GAM36989.1 - 1.3e-08 35.0 0.0 3.4e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF3974 PF13120.6 GAM36989.1 - 0.11 12.6 0.6 0.6 10.2 0.1 2.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3974) Podoplanin PF05808.11 GAM36991.1 - 0.0015 18.7 4.1 0.0026 17.9 4.1 1.3 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 GAM36991.1 - 0.016 14.6 0.7 0.016 14.6 0.7 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Yip1 PF04893.17 GAM36991.1 - 0.037 13.7 2.6 0.077 12.7 0.1 2.2 2 0 0 2 2 2 0 Yip1 domain DUF5305 PF17231.2 GAM36991.1 - 0.086 12.2 1.0 0.12 11.7 1.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) NAM-associated PF14303.6 GAM36991.1 - 0.1 13.3 1.8 0.14 12.9 1.8 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain ORC6 PF05460.13 GAM36991.1 - 0.21 10.8 4.5 0.26 10.5 4.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MGC-24 PF05283.11 GAM36991.1 - 7.9 6.9 25.2 0.24 11.8 15.8 2.1 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Gly_transf_sug PF04488.15 GAM36992.1 - 1.9e-09 38.0 0.0 3.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 GAM36992.1 - 0.05 13.0 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein DUF4816 PF16086.5 GAM36992.1 - 2.6 8.0 6.8 0.4 10.6 2.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4816) MFS_1 PF07690.16 GAM36993.1 - 0.0017 17.4 10.7 0.002 17.1 10.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Pox_A14 PF05767.12 GAM36993.1 - 0.13 12.5 0.7 0.23 11.7 0.5 1.6 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF1240 PF06836.12 GAM36993.1 - 0.13 12.8 0.7 0.21 12.1 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) DUF389 PF04087.14 GAM36993.1 - 0.23 11.5 3.9 0.55 10.3 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF389) NmrA PF05368.13 GAM36994.1 - 2.6e-33 115.5 0.0 3.4e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM36994.1 - 2.4e-06 27.6 0.0 3.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM36994.1 - 0.00021 20.8 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM36994.1 - 0.049 12.6 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 GAM36994.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF3152 PF11350.8 GAM36994.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Sugar_tr PF00083.24 GAM36995.1 - 2e-87 293.9 21.6 2.4e-87 293.7 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM36995.1 - 3.1e-16 59.3 15.9 3.1e-16 59.3 15.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM36995.1 - 0.0033 15.9 2.6 0.0033 15.9 2.6 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sulfatase PF00884.23 GAM36996.1 - 5.6e-42 144.2 0.0 7.6e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 GAM36996.1 - 1.2e-05 25.5 0.1 2.8e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 GAM36996.1 - 1.8e-05 23.6 0.0 2.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 GAM36996.1 - 0.0067 16.1 0.2 0.16 11.6 0.2 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Fungal_trans PF04082.18 GAM36997.1 - 3.5e-09 36.1 0.1 5.7e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.7 GAM36997.1 - 0.0015 19.2 0.0 0.0036 17.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 GAM36997.1 - 0.005 16.5 0.0 3 7.5 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase DUF676 PF05057.14 GAM36997.1 - 0.0073 15.8 0.2 0.018 14.6 0.2 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 GAM36997.1 - 0.069 12.7 0.0 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 GAM36997.1 - 0.093 12.4 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Hydrolase_4 PF12146.8 GAM36997.1 - 0.17 11.1 0.0 0.34 10.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TPR_12 PF13424.6 GAM36998.1 - 2.3e-44 149.5 7.1 4.1e-13 49.4 0.2 6.9 2 2 3 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 GAM36998.1 - 2.1e-32 110.1 15.6 4.1e-07 29.6 0.1 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAM36998.1 - 3.1e-09 36.2 13.7 0.045 13.8 0.1 8.6 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM36998.1 - 2.6e-08 33.3 3.0 1.2 9.4 0.0 6.2 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM36998.1 - 3.4e-07 29.9 11.5 7.6e-06 25.5 4.6 3.8 2 1 0 2 2 2 1 MalT-like TPR region TPR_4 PF07721.14 GAM36998.1 - 1e-06 28.8 1.5 0.26 12.0 0.4 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 GAM36998.1 - 4.7e-06 26.0 0.0 4e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.6 GAM36998.1 - 1.7e-05 25.2 16.4 0.028 14.9 0.5 6.4 4 3 3 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM36998.1 - 2.1e-05 24.4 2.4 2.2 8.7 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 GAM36998.1 - 0.00014 22.2 17.7 0.19 12.1 0.7 6.3 4 1 2 6 6 6 2 Tetratricopeptide repeat DUF676 PF05057.14 GAM36998.1 - 0.00085 18.9 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_16 PF13432.6 GAM36998.1 - 0.0023 18.5 10.1 0.26 11.9 0.1 6.2 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM36998.1 - 0.0042 17.4 1.7 0.81 10.2 0.1 4.8 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM36998.1 - 0.016 15.8 4.9 26 5.7 0.1 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM36998.1 - 0.016 16.0 21.7 3.7 8.6 0.2 8.4 8 1 1 9 9 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM36998.1 - 0.023 14.5 2.6 13 5.8 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_16 PF13191.6 GAM36998.1 - 0.65 10.4 4.2 0.94 9.8 0.0 3.2 3 1 1 4 4 3 0 AAA ATPase domain zf-H2C2_2 PF13465.6 GAM36999.1 - 1.1e-06 28.7 8.3 1.6e-05 25.1 1.4 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-Di19 PF05605.12 GAM36999.1 - 0.00037 20.7 4.8 0.00067 19.9 4.8 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 GAM36999.1 - 0.0004 21.0 15.2 0.031 15.1 5.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM36999.1 - 0.058 13.9 14.7 0.19 12.3 7.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 GAM36999.1 - 1.3 9.4 9.4 4.5 7.7 0.8 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding NACHT PF05729.12 GAM37000.1 - 5.3e-05 23.2 0.0 0.43 10.5 0.1 2.4 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 GAM37000.1 - 0.0052 17.2 0.1 0.012 16.0 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM37000.1 - 0.012 15.9 0.1 0.038 14.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 GAM37000.1 - 0.039 13.2 0.5 0.4 9.9 0.1 2.4 2 1 0 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.6 GAM37000.1 - 0.06 13.9 0.4 0.49 11.0 0.3 2.4 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAM37000.1 - 0.066 13.3 0.3 0.19 11.8 0.3 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 GAM37000.1 - 0.12 12.9 0.3 0.36 11.3 0.3 1.7 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 GAM37000.1 - 0.29 11.2 2.2 0.55 10.3 0.0 2.5 4 0 0 4 4 4 0 AAA domain kleA_kleC PF17383.2 GAM37002.1 - 0.11 12.9 1.0 0.22 11.9 1.0 1.5 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A AA_permease_2 PF13520.6 GAM37003.1 - 3.3e-68 230.5 50.1 4.5e-68 230.0 50.1 1.2 1 0 0 1 1 1 1 Amino acid permease QCR10 PF09796.9 GAM37003.1 - 2.3e-23 82.0 0.4 2.3e-23 82.0 0.4 3.5 3 0 0 3 3 3 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) AA_permease PF00324.21 GAM37003.1 - 1.9e-18 66.4 37.0 2.7e-18 65.8 37.0 1.2 1 0 0 1 1 1 1 Amino acid permease Thioredoxin PF00085.20 GAM37004.1 - 1.5e-42 143.7 0.0 8.7e-22 77.1 0.0 4.3 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 GAM37004.1 - 3e-14 53.3 0.0 2.4e-05 24.3 0.0 4.3 3 1 1 4 4 4 4 Thioredoxin-like domain Thioredoxin_2 PF13098.6 GAM37004.1 - 2.2e-05 24.9 1.9 0.4 11.1 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAM37004.1 - 0.00015 22.0 0.6 4.5 7.7 0.1 4.4 3 2 1 4 4 4 1 Thioredoxin-like HyaE PF07449.11 GAM37004.1 - 0.0014 18.6 0.0 0.38 10.7 0.0 3.2 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Calsequestrin PF01216.17 GAM37004.1 - 0.0068 15.5 0.6 0.042 12.9 0.3 2.1 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_3 PF13192.6 GAM37004.1 - 0.052 13.6 0.1 2.6 8.1 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin domain Fungus-induced PF10917.8 GAM37004.1 - 0.059 13.7 4.0 0.055 13.8 2.5 1.7 1 1 0 1 1 1 0 Fungus-induced protein Thioredoxin_7 PF13899.6 GAM37004.1 - 0.065 13.4 1.5 0.23 11.7 0.1 2.6 3 0 0 3 3 3 0 Thioredoxin-like ETC_C1_NDUFA5 PF04716.14 GAM37005.1 - 3.4e-29 100.5 1.4 3.4e-26 90.8 0.0 2.4 2 0 0 2 2 2 2 ETC complex I subunit conserved region Ku_PK_bind PF08785.11 GAM37005.1 - 0.0021 18.2 0.0 0.0049 17.0 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Coatomer_WDAD PF04053.14 GAM37006.1 - 6.1e-172 572.7 0.0 2.4e-171 570.7 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 GAM37006.1 - 8.7e-38 127.7 7.5 1e-05 26.2 0.0 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM37006.1 - 8.4e-09 35.6 0.1 3.6 8.0 0.1 6.3 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM37006.1 - 1.5e-05 23.9 3.2 0.25 10.0 0.1 4.3 1 1 4 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 GAM37006.1 - 0.025 14.6 0.0 15 5.6 0.0 3.5 1 1 3 4 4 4 0 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 GAM37006.1 - 0.062 13.5 0.1 0.24 11.7 0.0 2.0 1 1 1 2 2 2 0 C terminal of Calcineurin-like phosphoesterase SUR7 PF06687.12 GAM37007.1 - 1.9e-27 96.3 7.4 2.3e-27 96.0 7.4 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 GAM37007.1 - 6 6.7 12.8 0.93 9.4 8.1 1.8 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Mannitol_dh_C PF08125.13 GAM37008.1 - 3.7e-46 157.6 0.1 6.1e-46 156.9 0.1 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 GAM37008.1 - 2.8e-18 66.5 1.9 4.8e-18 65.8 0.3 2.0 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 GAM37008.1 - 0.0022 17.6 0.5 0.0022 17.6 0.5 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 GAM37008.1 - 0.0044 16.9 2.2 0.018 14.9 0.2 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UPF0052 PF01933.18 GAM37008.1 - 0.12 11.6 2.0 0.17 11.1 0.5 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0052 Ribosomal_S30AE PF02482.19 GAM37008.1 - 0.13 13.0 3.6 4.1 8.3 0.0 3.8 2 1 1 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein RRM_3 PF08777.11 GAM37008.1 - 0.15 12.2 8.5 0.55 10.3 0.0 3.2 3 2 1 4 4 4 0 RNA binding motif DIOX_N PF14226.6 GAM37009.1 - 1.3e-27 96.9 0.0 2.4e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM37009.1 - 1.9e-23 82.8 0.0 3.4e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ZZ PF00569.17 GAM37010.1 - 4.3e-10 39.3 4.1 8.5e-10 38.3 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 GAM37010.1 - 4.3e-10 39.6 0.1 1.5e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.17 GAM37010.1 - 1.3e-08 35.1 0.3 5.1e-08 33.2 0.0 2.2 3 0 0 3 3 3 1 SWIRM domain Pkinase PF00069.25 GAM37011.1 - 2.4e-70 236.9 0.0 3.1e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM37011.1 - 6.3e-34 117.4 0.0 9.1e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAM37011.1 - 6.7e-08 33.1 0.1 2e-07 31.6 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 GAM37011.1 - 4.7e-07 29.1 0.1 7.3e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAM37011.1 - 0.0058 16.0 0.0 0.013 14.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 GAM37011.1 - 0.038 13.6 0.1 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 C2 PF00168.30 GAM37011.1 - 0.041 14.2 0.0 0.085 13.2 0.0 1.4 1 0 0 1 1 1 0 C2 domain Dcc1 PF09724.9 GAM37011.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 Sugar_tr PF00083.24 GAM37012.1 - 1.2e-23 83.8 21.7 1.6e-13 50.4 6.3 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM37012.1 - 1.2e-07 31.0 33.1 3.6e-06 26.2 8.1 3.1 1 1 0 2 2 2 2 Major Facilitator Superfamily RCC1 PF00415.18 GAM37013.1 - 2.6e-32 111.2 13.9 6.5e-08 33.1 0.0 7.8 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM37013.1 - 1.6e-19 69.2 19.4 9.6e-07 28.4 0.1 6.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Crystall_2 PF09076.10 GAM37013.1 - 0.068 13.1 0.1 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 Beta/Gamma crystallin Rad9 PF04139.13 GAM37014.1 - 5.1e-43 147.3 0.9 9.2e-43 146.5 0.9 1.4 1 1 0 1 1 1 1 Rad9 Rad1 PF02144.16 GAM37014.1 - 2.1e-08 33.5 0.8 3.1e-06 26.5 0.4 2.9 1 1 1 2 2 2 1 Repair protein Rad1/Rec1/Rad17 HHH_5 PF14520.6 GAM37015.1 - 0.0095 16.5 0.6 0.03 14.9 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain Aldo_ket_red PF00248.21 GAM37016.1 - 1.3e-68 231.4 0.0 2.3e-68 230.5 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family DNA_pol_B PF00136.21 GAM37017.1 - 5e-117 391.4 3.2 7.2e-117 390.9 3.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 GAM37017.1 - 1.7e-70 236.5 0.6 4.1e-70 235.3 0.6 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.8 GAM37017.1 - 1.7e-25 88.8 7.0 1.7e-25 88.8 7.0 3.3 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_exo1 PF03104.19 GAM37017.1 - 3.9e-24 85.4 0.0 5.9e-21 75.0 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 GAM37017.1 - 0.0019 17.2 0.1 0.0046 15.9 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Phos_pyr_kin PF08543.12 GAM37018.1 - 3.4e-79 265.7 3.5 4.7e-79 265.2 3.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 GAM37018.1 - 3.3e-49 167.6 0.1 5.9e-26 91.6 0.0 2.2 1 1 1 2 2 2 2 TENA/THI-4/PQQC family PfkB PF00294.24 GAM37018.1 - 2.9e-07 30.1 0.1 0.0011 18.4 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase HK PF02110.15 GAM37018.1 - 0.005 16.3 2.9 0.045 13.1 0.4 2.4 2 1 0 2 2 2 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 GAM37018.1 - 0.026 14.0 2.7 0.023 14.2 1.3 1.6 2 0 0 2 2 2 0 Carbohydrate kinase Ran_BP1 PF00638.18 GAM37019.1 - 3.8e-19 69.1 0.0 8e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain PPR_2 PF13041.6 GAM37020.1 - 9e-16 57.8 0.0 2.2e-14 53.4 0.0 3.0 2 0 0 2 2 2 1 PPR repeat family Yip1 PF04893.17 GAM37020.1 - 1.1e-13 51.2 13.7 2e-13 50.4 13.7 1.4 1 0 0 1 1 1 1 Yip1 domain PPR_long PF17177.4 GAM37020.1 - 7.6e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAM37020.1 - 0.0012 18.9 0.2 2.6 8.5 0.0 3.5 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.6 GAM37020.1 - 0.021 14.9 0.0 3.1 7.9 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAM37020.1 - 0.047 13.4 0.0 0.17 11.6 0.0 2.0 1 0 0 1 1 1 0 PPR repeat DUF1282 PF06930.12 GAM37020.1 - 0.11 12.2 4.7 0.21 11.3 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DEAD PF00270.29 GAM37021.1 - 9.8e-50 168.7 0.0 7e-48 162.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM37021.1 - 4.4e-26 91.4 0.4 1.7e-14 54.1 0.0 2.9 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 GAM37021.1 - 0.00042 20.4 0.0 0.0017 18.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAM37021.1 - 0.0031 17.9 0.0 0.8 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF5335 PF17269.2 GAM37021.1 - 0.039 13.8 0.1 0.077 12.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) Helicase_C_2 PF13307.6 GAM37021.1 - 0.098 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain HDV_ag PF01517.18 GAM37022.1 - 0.0084 15.9 1.4 0.018 14.8 1.4 1.5 1 0 0 1 1 1 1 Hepatitis delta virus delta antigen FOXP-CC PF16159.5 GAM37022.1 - 0.12 13.0 0.9 0.24 12.0 0.7 1.7 1 1 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 GAM37022.1 - 0.13 12.8 0.2 0.3 11.6 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type YabA PF06156.13 GAM37022.1 - 7 7.3 8.0 2.8 8.6 0.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DEAD PF00270.29 GAM37023.1 - 1.6e-27 96.4 0.0 2.9e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 GAM37023.1 - 1.8e-16 60.6 0.2 2.4e-14 53.8 0.2 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 GAM37023.1 - 3.8e-13 49.8 0.1 1.8e-12 47.6 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM37023.1 - 7.2e-07 29.4 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 GAM37023.1 - 2.1e-05 24.9 0.0 5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like Formyl_trans_N PF00551.19 GAM37024.1 - 3.9e-35 121.2 0.1 4.4e-35 121.1 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase zf-RING_2 PF13639.6 GAM37026.1 - 1.9e-10 40.9 2.7 2.9e-10 40.3 2.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAM37026.1 - 1.9e-07 31.2 1.2 3.7e-07 30.3 1.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAM37026.1 - 5.1e-07 29.3 2.0 9.2e-07 28.5 2.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAM37026.1 - 6.1e-07 29.2 2.1 1e-06 28.5 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM37026.1 - 2.7e-06 27.1 2.7 4.1e-06 26.6 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM37026.1 - 0.00019 21.4 1.8 0.00035 20.5 1.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 GAM37026.1 - 0.00041 19.9 1.8 0.00064 19.3 1.8 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 GAM37026.1 - 0.00054 19.9 2.3 0.00081 19.3 2.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAM37026.1 - 0.03 14.4 0.3 0.055 13.5 0.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 GAM37026.1 - 0.032 14.3 3.6 0.051 13.7 3.6 1.3 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 GAM37026.1 - 0.054 13.4 1.7 0.084 12.7 1.7 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 GAM37026.1 - 0.12 12.4 0.6 0.24 11.5 0.6 1.3 1 0 0 1 1 1 0 Zinc-finger zf-Nse PF11789.8 GAM37026.1 - 0.13 12.1 0.8 0.3 10.9 0.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 GAM37026.1 - 0.15 12.0 0.9 0.24 11.3 0.9 1.3 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 GAM37026.1 - 0.19 12.0 3.4 0.31 11.3 3.4 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 GAM37026.1 - 0.32 10.9 2.0 0.47 10.4 2.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) VPS9 PF02204.18 GAM37027.1 - 1.7e-27 95.7 0.0 2.8e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain ECM11 PF15463.6 GAM37028.1 - 2.4e-47 160.8 0.0 2.4e-47 160.8 0.0 3.3 3 1 0 3 3 3 1 Extracellular mutant protein 11 PRIMA1 PF16101.5 GAM37028.1 - 8.4 6.5 8.8 26 4.9 8.8 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RNA_pol_I_TF PF04090.12 GAM37029.1 - 1.5e-10 40.9 0.0 3.4e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor Lipase_3 PF01764.25 GAM37030.1 - 2.8e-06 27.3 0.0 7.8e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 GAM37030.1 - 0.081 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein WIYLD PF10440.9 GAM37030.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain Hydrolase_4 PF12146.8 GAM37030.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PHD_like PF12910.7 GAM37031.1 - 0.0032 17.5 0.1 0.0046 17.0 0.1 1.2 1 0 0 1 1 1 1 Antitoxin of toxin-antitoxin, RelE / RelB, TA system MFS_1 PF07690.16 GAM37032.1 - 5.1e-35 121.0 45.4 5.1e-35 121.0 45.4 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM37032.1 - 2.6e-11 43.1 16.5 2.6e-11 43.1 16.5 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter NDUF_B8 PF05821.11 GAM37032.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DHO_dh PF01180.21 GAM37035.1 - 1.2e-63 215.1 0.0 1.5e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.17 GAM37035.1 - 0.017 14.6 0.1 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 PcrB family FMN_dh PF01070.18 GAM37035.1 - 0.025 13.6 0.1 0.3 10.1 0.2 2.5 2 1 0 2 2 2 0 FMN-dependent dehydrogenase NMO PF03060.15 GAM37035.1 - 0.044 13.2 0.3 0.11 11.9 0.1 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase TIM PF00121.18 GAM37036.1 - 1.7e-40 138.9 0.0 2.3e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase DUF1921 PF09081.10 GAM37036.1 - 0.019 15.2 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1921) LacAB_rpiB PF02502.18 GAM37037.1 - 4.5e-41 140.1 0.0 5.1e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 GAM37037.1 - 0.028 14.5 0.0 0.05 13.6 0.0 1.5 1 1 0 1 1 1 0 Glycine-rich SFCGS U-box PF04564.15 GAM37038.1 - 9.2e-22 77.0 0.0 1.7e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 GAM37038.1 - 2.3e-08 33.5 0.2 5.9e-05 22.7 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM37038.1 - 4.8e-08 32.5 0.9 0.0011 18.9 0.0 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM37038.1 - 2.6e-07 31.2 4.6 1.1e-05 25.9 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM37038.1 - 2e-05 24.2 0.0 0.00014 21.5 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 GAM37038.1 - 9.2e-05 22.9 2.3 0.0041 17.6 0.0 2.8 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM37038.1 - 0.0001 22.8 4.8 0.13 13.2 0.0 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM37038.1 - 0.00018 21.7 3.2 0.45 10.8 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 GAM37038.1 - 0.00023 21.8 4.5 0.00048 20.8 4.5 1.5 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_17 PF13431.6 GAM37038.1 - 0.0049 17.1 0.2 0.12 12.8 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM37038.1 - 0.011 15.8 1.7 0.028 14.6 0.0 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM37038.1 - 0.017 15.3 0.6 0.26 11.6 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM37038.1 - 0.019 15.0 0.7 3.4 7.9 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat GvpG PF05120.12 GAM37038.1 - 0.025 14.6 0.7 0.057 13.4 0.7 1.6 1 0 0 1 1 1 0 Gas vesicle protein G CdvA PF18822.1 GAM37038.1 - 0.03 14.1 6.1 0.17 11.7 1.4 2.5 2 1 1 3 3 2 0 CdvA-like coiled-coil domain Phasin_2 PF09361.10 GAM37038.1 - 0.046 14.0 4.6 0.12 12.7 4.6 1.7 1 0 0 1 1 1 0 Phasin protein ANAPC3 PF12895.7 GAM37038.1 - 0.053 13.7 0.1 58 4.0 0.0 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-Nse PF11789.8 GAM37038.1 - 0.074 12.9 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 GAM37038.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.6 1 1 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein ADH_zinc_N PF00107.26 GAM37039.1 - 1.6e-16 60.5 0.1 3.5e-16 59.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM37039.1 - 5.8e-13 48.7 0.2 8.8e-13 48.1 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM37039.1 - 2.8e-07 31.6 0.0 3.3e-05 24.9 0.0 2.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAM37039.1 - 4.1e-05 23.2 0.1 9.8e-05 21.9 0.1 1.6 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ACBP PF00887.19 GAM37040.1 - 7.1e-19 67.8 1.1 8e-19 67.6 1.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein MqsR_toxin PF15723.5 GAM37040.1 - 0.062 13.7 0.1 0.067 13.6 0.1 1.2 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA FERM_M PF00373.18 GAM37040.1 - 0.074 13.5 0.1 0.086 13.2 0.1 1.4 1 1 0 1 1 1 0 FERM central domain Tyr-DNA_phospho PF06087.12 GAM37041.1 - 4.4e-168 559.6 0.0 5.2e-168 559.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 GAM37041.1 - 0.0038 17.1 0.1 0.49 10.3 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain NACHT PF05729.12 GAM37042.1 - 6.1e-07 29.5 0.0 1.8e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAM37042.1 - 0.00011 22.7 0.1 0.0013 19.2 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain Goodbye PF17109.5 GAM37042.1 - 0.00025 21.5 0.0 0.00064 20.2 0.0 1.7 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain Ank PF00023.30 GAM37042.1 - 0.0017 18.7 0.0 2.6 8.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 GAM37042.1 - 0.0029 18.2 0.0 0.065 13.8 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM37042.1 - 0.019 15.5 0.0 0.068 13.8 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) KAP_NTPase PF07693.14 GAM37042.1 - 0.051 12.8 0.8 0.093 12.0 0.1 1.8 2 0 0 2 2 2 0 KAP family P-loop domain Ank_3 PF13606.6 GAM37042.1 - 0.054 14.1 0.0 4.6 8.1 0.0 3.2 2 0 0 2 2 2 0 Ankyrin repeat AAA_22 PF13401.6 GAM37042.1 - 0.075 13.3 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAM37042.1 - 0.13 12.6 0.0 0.42 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Ank PF00023.30 GAM37043.1 - 1.4e-06 28.5 0.1 0.00024 21.4 0.1 3.5 2 1 1 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 GAM37043.1 - 2.5e-05 24.8 0.0 0.67 10.6 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM37043.1 - 0.0039 17.7 0.1 0.18 12.4 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM37043.1 - 0.0047 17.2 0.5 40 4.7 0.1 4.5 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM37043.1 - 0.0068 16.8 1.1 4.6 8.1 0.2 4.9 5 1 0 5 5 5 1 Ankyrin repeat DIE2_ALG10 PF04922.12 GAM37044.1 - 1.7e-105 353.5 7.0 2.4e-105 353.1 7.0 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Sld5 PF05916.11 GAM37045.1 - 2.4e-32 111.7 0.0 5.2e-32 110.6 0.0 1.5 1 1 0 1 1 1 1 GINS complex protein TFIIE_alpha PF02002.17 GAM37045.1 - 0.18 11.6 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit CUE PF02845.16 GAM37046.1 - 1.1e-10 40.9 0.0 1.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 GAM37046.1 - 0.012 15.2 9.1 0.031 13.9 9.1 1.7 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) DUF1151 PF06625.11 GAM37046.1 - 0.026 14.4 2.4 0.04 13.9 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) SMC_N PF02463.19 GAM37047.1 - 1.3e-63 214.3 3.1 1.4e-62 211.0 3.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAM37047.1 - 1.3e-20 73.8 0.5 7.2e-20 71.5 0.1 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GAM37047.1 - 3.2e-10 40.3 6.2 0.0002 21.3 0.2 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAM37047.1 - 6e-09 36.7 15.5 6e-09 36.7 15.5 6.9 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.6 GAM37047.1 - 0.00012 21.8 0.2 0.00029 20.5 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.7 GAM37047.1 - 0.0014 18.2 23.6 0.0014 18.2 23.6 6.4 2 2 4 6 6 6 2 Mechanosensitive ion channel porin domain HIP1_clath_bdg PF16515.5 GAM37047.1 - 0.0058 17.2 8.3 0.0058 17.2 8.3 9.1 3 2 8 11 11 11 1 Clathrin-binding domain of Huntingtin-interacting protein 1 NOT2_3_5 PF04153.18 GAM37048.1 - 5.6e-28 97.6 1.6 1.1e-27 96.7 0.0 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Presenilin PF01080.17 GAM37048.1 - 8.8 5.0 5.5 11 4.6 5.5 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 GAM37048.1 - 9.5 6.1 22.3 13 5.7 22.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MRP-L47 PF06984.13 GAM37049.1 - 3.5e-18 65.5 1.5 5.9e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.12 GAM37049.1 - 1.2 8.6 2.3 1.8 8.0 2.3 1.2 1 0 0 1 1 1 0 Clc-like GDI PF00996.18 GAM37050.1 - 9.8e-195 647.1 0.0 1.1e-194 646.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 GAM37050.1 - 0.008 16.4 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAM37050.1 - 0.011 16.3 0.3 0.36 11.4 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 4HBT PF03061.22 GAM37051.1 - 4.1e-13 49.5 0.1 5.8e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 GAM37051.1 - 0.0016 18.7 0.6 0.0046 17.3 0.1 1.8 1 1 1 2 2 2 1 Thioesterase-like superfamily DUF1192 PF06698.11 GAM37051.1 - 0.13 12.3 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) ORC4_C PF14629.6 GAM37052.1 - 1.2e-45 155.6 0.0 2.3e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 GAM37052.1 - 1.4e-15 58.1 0.1 9.7e-15 55.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAM37052.1 - 3.3e-07 30.7 0.0 9.7e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAM37052.1 - 3.7e-07 30.6 0.1 1.9e-06 28.3 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GAM37052.1 - 4.1e-07 30.1 0.3 1.1e-06 28.7 0.1 1.8 2 1 0 2 2 1 1 NACHT domain DUF815 PF05673.13 GAM37052.1 - 4.7e-06 26.0 0.0 7.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 GAM37052.1 - 5e-05 22.7 0.0 9.2e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain ATPase_2 PF01637.18 GAM37052.1 - 5.7e-05 23.1 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 GAM37052.1 - 0.00011 22.6 0.0 0.00031 21.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAM37052.1 - 0.00078 18.7 0.1 0.0014 17.9 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_29 PF13555.6 GAM37052.1 - 0.001 18.8 0.7 0.0022 17.7 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 GAM37052.1 - 0.0017 17.8 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.6 GAM37052.1 - 0.0023 18.0 0.1 0.012 15.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 GAM37052.1 - 0.0025 17.0 0.0 0.03 13.5 0.0 2.2 2 1 0 2 2 2 1 G-protein alpha subunit AAA_30 PF13604.6 GAM37052.1 - 0.003 17.3 0.6 0.008 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain PIF1 PF05970.14 GAM37052.1 - 0.0041 16.3 0.1 0.01 15.0 0.1 1.7 1 0 0 1 1 1 1 PIF1-like helicase AAA_7 PF12775.7 GAM37052.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 GAM37052.1 - 0.035 14.6 0.0 0.11 13.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 GAM37052.1 - 0.045 13.1 0.4 0.093 12.1 0.4 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Mg_chelatase PF01078.21 GAM37052.1 - 0.051 13.0 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 GAM37052.1 - 0.054 13.3 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.12 GAM37052.1 - 0.054 12.9 0.2 0.14 11.6 0.1 1.6 2 0 0 2 2 2 0 Poxvirus A32 protein RNA_helicase PF00910.22 GAM37052.1 - 0.055 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 GAM37052.1 - 0.062 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 GAM37052.1 - 0.072 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 GAM37052.1 - 0.1 12.7 0.5 0.39 10.8 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain TsaE PF02367.17 GAM37052.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RGS PF00615.19 GAM37053.1 - 2.1e-33 115.1 0.0 5e-33 113.9 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 GAM37053.1 - 5.9e-26 90.3 0.0 7.3e-19 67.6 0.0 3.4 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Replic_Relax PF13814.6 GAM37053.1 - 0.0073 16.4 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 2 Replication-relaxation CDC73_C PF05179.14 GAM37054.1 - 4.5e-47 159.7 0.0 2.1e-46 157.5 0.0 2.1 1 1 1 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal RIG-I_C PF18119.1 GAM37054.1 - 0.35 10.9 6.5 0.78 9.8 1.0 2.4 1 1 1 2 2 2 0 RIG-I receptor C-terminal domain Prominin PF05478.11 GAM37054.1 - 0.61 8.0 4.1 1 7.2 4.1 1.2 1 0 0 1 1 1 0 Prominin DUF3510 PF12022.8 GAM37054.1 - 0.77 10.2 10.4 0.89 9.9 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) PIN_12 PF16289.5 GAM37055.1 - 0.0029 18.1 3.5 0.0051 17.3 2.3 2.0 1 1 1 2 2 2 1 PIN domain DUF445 PF04286.12 GAM37055.1 - 0.029 14.2 9.2 0.04 13.7 6.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF445) RicinB_lectin_2 PF14200.6 GAM37055.1 - 0.037 14.8 0.0 0.087 13.6 0.0 1.7 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like DUF3194 PF11419.8 GAM37055.1 - 0.15 12.5 5.7 0.78 10.1 0.2 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3194) RhoGEF PF00621.20 GAM37055.1 - 0.17 12.1 2.1 0.35 11.1 1.4 1.9 2 0 0 2 2 1 0 RhoGEF domain Prominin PF05478.11 GAM37055.1 - 0.26 9.2 2.8 0.38 8.7 2.8 1.2 1 0 0 1 1 1 0 Prominin MMACHC PF16690.5 GAM37055.1 - 0.28 10.8 2.5 12 5.5 0.1 2.6 1 1 0 2 2 2 0 Methylmalonic aciduria and homocystinuria type C family ING PF12998.7 GAM37055.1 - 0.4 11.3 5.1 2.7 8.6 0.8 3.0 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Exonuc_VII_L PF02601.15 GAM37055.1 - 0.53 9.8 5.0 0.87 9.1 5.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3417 PF11897.8 GAM37055.1 - 1 9.8 5.7 15 6.1 0.2 3.7 3 1 1 4 4 3 0 Protein of unknown function (DUF3417) HrpE PF06188.12 GAM37055.1 - 1.5 8.7 6.7 23 4.8 0.7 3.3 2 1 1 3 3 3 0 HrpE/YscL/FliH and V-type ATPase subunit E Syntaxin_2 PF14523.6 GAM37055.1 - 2.6 8.5 6.9 12 6.3 6.9 2.1 1 1 0 1 1 1 0 Syntaxin-like protein ApoLp-III PF07464.11 GAM37055.1 - 2.9 8.0 9.6 1.6 8.8 3.3 2.7 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) NBD94 PF16830.5 GAM37055.1 - 3.1 8.3 6.2 1.6 9.1 0.4 3.0 2 1 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH YpjP PF14005.6 GAM37055.1 - 9 6.3 8.4 1.9 8.6 1.8 2.8 2 1 1 3 3 3 0 YpjP-like protein LAMTOR PF15454.6 GAM37056.1 - 0.036 14.7 0.3 0.07 13.7 0.3 1.5 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF445 PF04286.12 GAM37057.1 - 0.0084 16.0 10.4 0.012 15.5 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF5314 PF17241.2 GAM37057.1 - 0.015 15.0 6.5 0.24 11.1 2.1 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5314) DUF637 PF04830.13 GAM37057.1 - 0.017 15.0 8.6 0.55 10.0 8.5 2.3 1 1 0 1 1 1 0 Possible hemagglutinin (DUF637) DNTTIP1_dimer PF18192.1 GAM37057.1 - 0.032 14.6 9.0 0.34 11.3 3.8 3.3 1 1 2 3 3 3 0 DNTTIP1 dimerisation domain YpjP PF14005.6 GAM37057.1 - 0.058 13.5 10.2 1.2 9.2 1.7 2.9 1 1 2 3 3 3 0 YpjP-like protein EcsC PF12787.7 GAM37057.1 - 0.062 13.0 4.9 5.6 6.6 4.9 2.7 1 1 0 1 1 1 0 EcsC protein family Spo0A_C PF08769.11 GAM37057.1 - 0.65 10.1 7.0 1.5e+02 2.5 7.0 3.0 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal DUF3819 PF12842.7 GAM37057.1 - 1.3 9.0 10.7 5 7.0 8.5 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3819) Ribosomal_S5 PF00333.20 GAM37057.1 - 1.3 9.0 11.7 1.8 8.6 0.6 4.1 1 1 1 2 2 2 0 Ribosomal protein S5, N-terminal domain COMPASS-Shg1 PF05205.12 GAM37057.1 - 1.4 9.7 8.2 6.2 7.6 6.1 2.6 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Trns_repr_metal PF02583.17 GAM37057.1 - 5.2 7.5 9.7 38 4.7 5.2 2.8 1 1 1 2 2 2 0 Metal-sensitive transcriptional repressor ARGLU PF15346.6 GAM37057.1 - 7 6.5 15.5 4.2e+02 0.8 14.8 2.7 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 HK97-gp10_like PF04883.12 GAM37057.1 - 7.7 7.6 7.0 8.6 7.4 3.2 2.6 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component SET PF00856.28 GAM37058.1 - 3.7e-07 30.7 1.0 1.3e-05 25.7 0.1 3.1 2 1 0 2 2 2 1 SET domain PHD PF00628.29 GAM37058.1 - 1.9e-05 24.4 11.1 3.7e-05 23.5 11.1 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 GAM37058.1 - 4.1 7.4 9.2 1.1 9.2 5.9 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 WD40 PF00400.32 GAM37059.1 - 1e-11 45.2 14.8 0.0019 19.0 0.2 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM37059.1 - 0.00096 19.4 0.1 0.08 13.2 0.0 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Rav1p_C PF12234.8 GAM37059.1 - 0.055 11.9 0.0 0.083 11.3 0.0 1.2 1 0 0 1 1 1 0 RAVE protein 1 C terminal Glycos_transf_4 PF00953.21 GAM37060.1 - 8.7e-33 113.6 10.7 8.7e-33 113.6 10.7 2.5 3 1 0 3 3 3 1 Glycosyl transferase family 4 p450 PF00067.22 GAM37061.1 - 9.2e-53 179.6 0.1 1.3e-52 179.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 GAM37062.1 - 1.7e-19 70.2 0.0 2.6e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain P5CR_dimer PF14748.6 GAM37062.1 - 4.1e-18 65.5 3.4 4.1e-18 65.5 3.4 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation Methyltransf_25 PF13649.6 GAM37062.1 - 5.5e-09 36.6 0.0 1.8e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM37062.1 - 1.4e-06 28.2 0.0 0.0081 16.0 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAM37062.1 - 1.9e-06 28.5 0.0 1.8e-05 25.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM37062.1 - 1.7e-05 25.4 0.0 3.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain F420_oxidored PF03807.17 GAM37062.1 - 0.00057 20.4 0.0 0.0016 19.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent MTS PF05175.14 GAM37062.1 - 0.0042 16.6 0.0 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 GAM37062.1 - 0.0073 16.4 0.0 0.019 15.1 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 GAM37062.1 - 0.024 14.0 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain Amidohydro_2 PF04909.14 GAM37064.1 - 4.9e-07 29.8 0.0 1.1e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 GAM37064.1 - 2.7e-05 23.7 0.5 0.00038 19.9 0.5 2.5 1 1 0 1 1 1 1 Amidohydrolase family Aconitase PF00330.20 GAM37065.1 - 5.6e-163 543.2 0.0 6.8e-163 542.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAM37065.1 - 1.7e-41 141.6 0.0 4.1e-41 140.4 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain Alpha-amylase PF00128.24 GAM37066.1 - 2.7e-16 60.1 1.8 1.8e-15 57.4 1.1 2.5 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 GAM37066.1 - 2.4e-15 56.9 0.1 4.5e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GAM37066.1 - 3.7e-05 23.3 0.0 7.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAM37066.1 - 0.014 15.4 0.0 0.046 13.7 0.0 1.9 1 0 0 1 1 1 0 Glycosyltransferase Family 4 DUF373 PF04123.13 GAM37066.1 - 0.23 10.9 6.7 0.55 9.6 6.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Insulin_TMD PF17870.1 GAM37066.1 - 2.1 8.5 7.9 8.2 6.6 0.1 3.6 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment Pribosyltran PF00156.27 GAM37067.1 - 3.9e-13 49.2 0.2 6.8e-13 48.4 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MMACHC PF16690.5 GAM37067.1 - 0.18 11.4 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type C family MTHFR PF02219.17 GAM37068.1 - 3.7e-114 380.9 0.0 4.9e-114 380.5 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ASFV_J13L PF05568.11 GAM37069.1 - 0.038 13.8 3.7 0.12 12.1 3.7 1.9 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF2418 PF10332.9 GAM37070.1 - 7.4e-38 129.0 3.2 3.8e-37 126.7 0.6 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF2418) FIN1 PF17300.2 GAM37070.1 - 0.021 14.3 0.9 0.04 13.4 0.9 1.4 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 ATP-synt_F PF01990.17 GAM37071.1 - 1e-32 112.3 0.0 1.2e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.13 GAM37071.1 - 0.043 13.6 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 E1_DerP2_DerF2 PF02221.15 GAM37072.1 - 8.7e-18 65.0 0.0 1.1e-17 64.7 0.0 1.0 1 0 0 1 1 1 1 ML domain Methyltransf_23 PF13489.6 GAM37073.1 - 2.6e-13 50.1 0.0 3.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM37073.1 - 1.9e-10 41.3 0.0 1.8e-09 38.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM37073.1 - 2.3e-09 37.8 0.0 6.5e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM37073.1 - 8.1e-06 25.7 0.0 0.00053 19.8 0.0 3.0 3 1 1 4 4 4 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM37073.1 - 1.2e-05 25.9 0.0 3.9e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAM37073.1 - 0.00058 19.4 0.0 0.0015 18.0 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 GAM37073.1 - 0.0025 18.0 0.0 0.0051 16.9 0.0 1.5 1 1 1 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 GAM37073.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain KH_8 PF17903.1 GAM37074.1 - 2.3e-31 107.7 0.0 4.9e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 GAM37074.1 - 0.016 15.1 0.0 0.044 13.6 0.0 1.8 1 0 0 1 1 1 0 KH domain DUF4746 PF15928.5 GAM37074.1 - 1.1 8.7 15.2 1.5 8.2 15.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RPN2_C PF18004.1 GAM37074.1 - 4.3 7.2 24.6 7.7 6.4 24.6 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4573 PF15140.6 GAM37075.1 - 0.00094 19.0 0.0 4.3 7.1 0.0 3.8 1 1 2 4 4 4 3 Domain of unknown function (DUF4573) ADH_N PF08240.12 GAM37076.1 - 5.7e-22 77.7 0.1 8.6e-22 77.1 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM37076.1 - 1.2e-20 73.8 0.0 2.4e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM37076.1 - 9.7e-10 39.6 0.0 1.7e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAM37076.1 - 0.00081 18.8 0.1 0.005 16.2 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAM37076.1 - 0.0029 17.0 0.4 0.005 16.2 0.1 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Helo_like_N PF17111.5 GAM37077.1 - 2.8e-75 252.3 6.2 3.2e-74 248.8 0.7 2.1 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins SesA PF17107.5 GAM37077.1 - 0.011 15.9 0.8 0.027 14.7 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Rab5-bind PF09311.11 GAM37077.1 - 0.018 14.5 0.2 0.018 14.5 0.2 2.7 3 0 0 3 3 3 0 Rabaptin-like protein Nas2_N PF18265.1 GAM37077.1 - 0.02 14.8 0.4 0.02 14.8 0.4 2.5 3 0 0 3 3 3 0 Nas2 N_terminal domain DUF2096 PF09869.9 GAM37077.1 - 0.038 14.1 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) Syntaxin-6_N PF09177.11 GAM37077.1 - 0.11 13.0 3.3 0.61 10.7 0.8 2.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal KxDL PF10241.9 GAM37077.1 - 0.21 11.9 8.7 1.6 9.1 0.4 3.6 3 1 0 3 3 3 0 Uncharacterized conserved protein TBCA PF02970.16 GAM37077.1 - 0.47 10.8 6.0 31 5.0 0.1 3.9 2 1 2 4 4 4 0 Tubulin binding cofactor A KASH_CCD PF14662.6 GAM37077.1 - 0.93 9.3 6.5 7.3 6.4 0.2 3.2 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 GAM37077.1 - 1 8.6 6.7 0.37 10.0 0.1 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3450) HWE_HK PF07536.14 GAM37077.1 - 1.3 9.8 3.7 5.1 7.9 1.9 2.6 2 0 0 2 2 2 0 HWE histidine kinase Toxin_2 PF00451.19 GAM37077.1 - 2.2 8.7 8.0 6.1 7.2 0.2 3.0 3 0 0 3 3 3 0 Scorpion short toxin, BmKK2 Vps51 PF08700.11 GAM37077.1 - 2.6 8.2 8.0 0.87 9.7 0.2 3.4 4 0 0 4 4 4 0 Vps51/Vps67 Helo_like_N PF17111.5 GAM37078.1 - 6.2e-92 306.7 6.3 1.6e-80 269.4 0.1 2.2 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins DUF1664 PF07889.12 GAM37078.1 - 0.005 16.9 8.0 3.1 7.9 0.6 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 GAM37078.1 - 0.038 12.9 13.3 0.53 9.1 1.2 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Prefoldin_2 PF01920.20 GAM37078.1 - 0.07 13.1 7.2 1.2 9.2 2.0 3.5 3 0 0 3 3 3 0 Prefoldin subunit RasGAP_C PF03836.15 GAM37078.1 - 0.1 12.8 7.1 0.25 11.5 0.0 3.7 2 1 1 4 4 4 0 RasGAP C-terminus PilJ PF13675.6 GAM37078.1 - 0.13 12.3 0.3 0.13 12.3 0.3 3.0 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4795 PF16043.5 GAM37078.1 - 0.3 10.7 9.9 1.3 8.6 2.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) FUSC PF04632.12 GAM37078.1 - 0.35 9.4 3.8 0.21 10.1 2.0 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family Seryl_tRNA_N PF02403.22 GAM37078.1 - 0.41 10.9 8.5 3.2 8.0 0.0 3.8 2 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF2730 PF10805.8 GAM37078.1 - 0.55 10.3 3.7 9.1 6.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) TCP PF03634.13 GAM37078.1 - 1.2 9.7 0.0 1.2 9.7 0.0 2.8 3 1 0 3 3 3 0 TCP family transcription factor Spc24 PF08286.11 GAM37078.1 - 1.7 9.0 13.3 1.3 9.3 1.2 3.5 4 0 0 4 4 4 0 Spc24 subunit of Ndc80 Syntaxin-6_N PF09177.11 GAM37078.1 - 3.8 8.1 11.9 4.9e+02 1.4 8.8 4.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal ING PF12998.7 GAM37078.1 - 5.7 7.6 8.5 0.71 10.5 0.7 2.8 3 0 0 3 3 2 0 Inhibitor of growth proteins N-terminal histone-binding SlyX PF04102.12 GAM37078.1 - 6.2 7.5 10.6 7.9 7.2 1.2 3.6 3 1 0 3 3 3 0 SlyX BAR_2 PF10455.9 GAM37080.1 - 5.9e-61 206.1 0.5 9e-61 205.5 0.5 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 GAM37080.1 - 2.6e-22 79.7 4.2 4.1e-21 75.7 4.2 2.1 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 GAM37080.1 - 0.011 15.5 0.1 0.46 10.1 0.0 2.3 2 0 0 2 2 2 0 BAR domain of APPL family ADH_zinc_N PF00107.26 GAM37081.1 - 4.3e-25 88.2 0.1 6.2e-25 87.7 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM37081.1 - 0.00026 22.0 0.0 0.00047 21.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MinC_N PF05209.13 GAM37081.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain Arv1 PF04161.13 GAM37082.1 - 1.1e-60 205.4 0.0 5.1e-52 177.1 0.0 2.3 2 0 0 2 2 2 2 Arv1-like family Fungal_trans_2 PF11951.8 GAM37083.1 - 2.5e-17 62.7 0.2 6e-13 48.4 0.1 3.2 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM37083.1 - 3.3e-07 30.3 12.2 5.8e-07 29.5 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAF1A PF12253.8 GAM37083.1 - 1.5 9.0 5.5 46 4.3 2.7 2.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A TFIIA PF03153.13 GAM37083.1 - 5.3 6.9 15.6 10 6.0 15.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_8 PF05148.15 GAM37084.1 - 1.6e-53 181.8 0.4 2.5e-50 171.4 0.1 3.3 3 1 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 GAM37084.1 - 2.1e-06 28.3 0.0 7.1e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM37084.1 - 6.2e-05 23.6 0.0 0.0023 18.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain DUF4471 PF14740.6 GAM37084.1 - 0.39 9.9 12.3 0.27 10.4 6.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Methyltransf_32 PF13679.6 GAM37084.1 - 1.4 8.9 0.0 1.4 8.9 0.0 3.2 3 1 0 3 3 3 0 Methyltransferase domain BSP_II PF05432.11 GAM37084.1 - 2.1 7.9 34.7 2.1 8.0 5.0 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Proteasome PF00227.26 GAM37085.1 - 8.1e-56 188.5 0.2 1e-55 188.2 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAM37085.1 - 1.5e-12 46.9 0.2 3.6e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 GAM37086.1 - 1e-68 232.2 0.0 1.7e-68 231.5 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 GAM37086.1 - 1.8e-62 211.6 3.5 1.8e-62 211.6 3.5 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal AMP-binding PF00501.28 GAM37087.1 - 1.3e-56 192.1 0.0 1.8e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM37087.1 - 0.0067 17.4 0.1 0.016 16.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 GAM37088.1 - 4.5e-65 219.6 1.3 2e-64 217.4 0.2 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAM37088.1 - 4.5e-43 145.8 0.3 1e-42 144.7 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 GAM37088.1 - 0.0013 18.8 0.0 0.0036 17.4 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 GAM37088.1 - 0.0046 16.6 0.7 0.018 14.6 0.9 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 GAM37088.1 - 0.0063 16.3 0.2 0.36 10.7 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SasG_E PF17041.5 GAM37088.1 - 0.11 12.5 0.4 0.33 11.0 0.4 1.8 1 0 0 1 1 1 0 E domain DUF1996 PF09362.10 GAM37089.1 - 1.1e-85 287.3 0.1 1.7e-85 286.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 GAM37089.1 - 3.2e-20 72.1 10.3 1.1e-19 70.4 10.3 2.0 1 0 0 1 1 1 1 WSC domain PhyH PF05721.13 GAM37090.1 - 7.2e-12 46.0 0.0 9.6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) GST_N PF02798.20 GAM37091.1 - 3.3e-09 37.0 0.0 2.1e-07 31.2 0.0 2.4 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM37091.1 - 7.9e-08 32.4 0.0 1.5e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM37091.1 - 1.1e-06 28.7 0.0 1.9e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM37091.1 - 3.3e-06 27.4 0.1 8.4e-05 22.9 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM37091.1 - 8.8e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM37091.1 - 0.003 17.8 0.0 0.018 15.4 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.16 GAM37092.1 - 2.5e-38 131.9 80.7 1.9e-30 106.0 57.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 GAM37093.1 - 5.9e-128 427.5 19.2 7.3e-128 427.2 19.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like VbhA PF18495.1 GAM37093.1 - 0.11 12.3 0.2 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 Antitoxin VbhA NAD_binding_2 PF03446.15 GAM37095.1 - 2.9e-21 76.3 0.0 4.8e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CIA30 PF08547.12 GAM37095.1 - 3.3e-21 75.9 0.1 6e-21 75.1 0.1 1.4 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NAD_binding_11 PF14833.6 GAM37095.1 - 7.7e-09 35.8 0.0 2.3e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 GAM37095.1 - 1.6e-05 25.0 0.0 3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 GAM37095.1 - 0.13 12.8 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAT PF04768.13 GAM37096.1 - 2.3e-48 164.1 0.0 5.7e-48 162.8 0.0 1.6 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase F-box-like PF12937.7 GAM37096.1 - 6e-07 29.3 3.0 7.1e-07 29.0 1.1 2.1 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 GAM37096.1 - 0.0026 17.7 0.4 0.011 15.6 0.1 2.2 2 0 0 2 2 2 1 F-box F-box PF00646.33 GAM37096.1 - 0.017 15.0 0.2 0.045 13.6 0.2 1.8 1 0 0 1 1 1 0 F-box domain FCD PF07729.12 GAM37096.1 - 0.12 12.8 0.2 0.43 11.0 0.1 2.0 2 0 0 2 2 2 0 FCD domain Gelsolin PF00626.22 GAM37097.1 - 2.1e-30 104.4 3.1 1.9e-11 43.7 0.0 3.4 3 1 0 3 3 3 3 Gelsolin repeat Invas_SpaK PF03519.14 GAM37097.1 - 0.3 11.2 1.4 7.1 6.8 0.1 2.5 2 0 0 2 2 2 0 Invasion protein B family p450 PF00067.22 GAM37098.1 - 7e-64 216.3 0.0 8.7e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 GAM37099.1 - 2.7e-17 62.8 0.0 4.6e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GalP_UDP_transf PF01087.22 GAM37100.1 - 1.2e-71 240.9 0.4 2.3e-70 236.8 0.1 2.5 3 0 0 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 GAM37100.1 - 2.7e-60 202.9 0.0 8.4e-60 201.3 0.0 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 GAM37100.1 - 0.0029 16.5 0.1 0.11 11.3 0.0 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4921) HIT PF01230.23 GAM37100.1 - 0.0046 17.7 0.0 0.062 14.0 0.0 2.3 2 1 0 2 2 2 1 HIT domain DcpS_C PF11969.8 GAM37100.1 - 0.17 12.4 0.0 0.43 11.1 0.0 1.6 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Erg28 PF03694.13 GAM37101.1 - 2.6e-40 137.2 2.6 3.1e-40 137.0 2.6 1.1 1 0 0 1 1 1 1 Erg28 like protein adh_short PF00106.25 GAM37102.1 - 1.3e-36 125.9 0.0 2.1e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Glycos_transf_1 PF00534.20 GAM37102.1 - 3e-22 79.0 0.0 5.8e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 adh_short_C2 PF13561.6 GAM37102.1 - 1.8e-20 73.5 0.0 3.6e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_trans_1_4 PF13692.6 GAM37102.1 - 5.3e-15 56.0 0.0 1e-14 55.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GAM37102.1 - 0.00021 21.6 0.0 0.00047 20.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 KR PF08659.10 GAM37102.1 - 0.00075 19.5 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM37102.1 - 0.0045 16.2 0.0 0.0078 15.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein T3SS_needle_reg PF09025.10 GAM37102.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator Cyclase PF04199.13 GAM37103.1 - 2.5e-12 47.2 0.0 3.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Aldedh PF00171.22 GAM37104.1 - 2.7e-152 507.5 0.0 3.1e-152 507.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAM37104.1 - 0.02 14.4 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Sugar_tr PF00083.24 GAM37105.1 - 4.2e-82 276.4 20.0 4.9e-82 276.2 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37105.1 - 2.5e-20 72.7 54.1 1.2e-16 60.6 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GET2 PF08690.10 GAM37105.1 - 0.25 11.0 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF2070 PF09843.9 GAM37105.1 - 0.35 9.1 6.0 0.66 8.2 6.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) adh_short_C2 PF13561.6 GAM37106.1 - 9.1e-59 198.8 0.0 1.4e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM37106.1 - 1.4e-45 155.2 0.2 2.5e-45 154.3 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.18 GAM37106.1 - 7.8e-10 38.2 1.1 1.3e-06 27.6 0.0 2.5 1 1 0 2 2 2 2 Fungal specific transcription factor domain KR PF08659.10 GAM37106.1 - 3e-07 30.5 0.1 8.7e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM37106.1 - 0.00048 19.7 0.6 0.0034 16.9 0.1 2.6 3 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GAM37106.1 - 0.046 14.0 0.4 0.5 10.6 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain Iso_dh PF00180.20 GAM37107.1 - 5.5e-105 351.3 0.0 6.3e-105 351.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3445 PF11927.8 GAM37108.1 - 4e-62 209.8 0.1 4.7e-62 209.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) HTH_Tnp_Tc5 PF03221.16 GAM37109.1 - 3.1e-09 36.7 0.8 7.6e-09 35.5 0.8 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_AraC PF00165.23 GAM37109.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family CDC27 PF09507.10 GAM37109.1 - 0.19 11.1 20.2 0.24 10.8 20.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HPIP PF15226.6 GAM37109.1 - 0.47 10.9 3.0 0.56 10.6 1.4 1.9 2 0 0 2 2 2 0 HCF-1 beta-propeller-interacting protein family Barttin PF15462.6 GAM37109.1 - 3.3 7.4 7.6 4.9 6.9 7.6 1.2 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) PPL5 PF18168.1 GAM37109.1 - 6.2 6.0 9.9 8.9 5.5 9.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 TPR_2 PF07719.17 GAM37110.1 - 9.3e-06 25.4 9.6 0.0061 16.6 0.4 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM37110.1 - 6.7e-05 22.8 2.3 0.0092 16.1 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM37110.1 - 0.00015 22.3 4.7 0.18 12.7 0.1 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM37110.1 - 0.0006 19.5 7.5 0.0085 15.9 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM37110.1 - 0.0023 18.1 3.0 0.027 14.7 0.4 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAM37110.1 - 0.0024 18.1 6.0 1 9.7 1.2 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM37110.1 - 0.0045 16.9 1.8 2.8 8.2 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAM37110.1 - 0.022 15.4 2.8 0.52 11.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM37110.1 - 0.024 14.3 1.8 0.97 9.2 0.1 3.1 2 1 0 2 2 2 0 TPR repeat TPR_19 PF14559.6 GAM37110.1 - 0.11 13.1 4.1 1.7 9.2 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAM37110.1 - 0.11 13.1 11.0 0.99 10.1 5.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.7 GAM37110.1 - 1.2 9.4 4.6 5.9 7.2 0.1 2.8 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_4 PF07721.14 GAM37110.1 - 1.5 9.7 3.9 6.7 7.7 1.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Alpha-amyl_C PF09071.10 GAM37111.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Alpha-amylase, C terminal PsbH PF00737.20 GAM37111.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Sugar_tr PF00083.24 GAM37112.1 - 8.4e-135 450.1 34.5 9.8e-135 449.9 34.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37112.1 - 4.1e-27 95.0 52.3 1.4e-22 80.1 32.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 GAM37112.1 - 0.02 15.1 2.2 0.02 15.1 2.2 4.3 5 1 0 5 5 5 0 Protein of unknown function (DUF2530) KR PF08659.10 GAM37113.1 - 2e-62 210.3 0.3 4.1e-62 209.3 0.3 1.5 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 GAM37113.1 - 2.5e-16 61.0 0.0 6.2e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 GAM37113.1 - 5.8e-11 42.2 0.1 1.2e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37113.1 - 2.5e-06 27.3 0.1 5.3e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 GAM37113.1 - 9.6e-05 22.4 0.0 0.00021 21.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 GAM37113.1 - 0.00016 21.9 0.0 0.00038 20.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 GAM37113.1 - 0.0015 18.5 0.1 0.0015 18.5 0.1 1.7 2 0 0 2 2 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAM37113.1 - 0.0083 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAM37113.1 - 0.049 13.1 0.0 0.1 12.0 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CoA_trans PF01144.23 GAM37113.1 - 0.054 12.9 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase Polysacc_synt_2 PF02719.15 GAM37113.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TraW_N PF12477.8 GAM37113.1 - 0.14 12.1 0.4 0.34 10.9 0.4 1.7 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal Sacchrp_dh_NADP PF03435.18 GAM37113.1 - 0.5 10.6 0.1 0.5 10.6 0.1 1.8 2 0 0 2 2 1 0 Saccharopine dehydrogenase NADP binding domain Retrotrans_gag PF03732.17 GAM37115.1 - 4.9e-06 26.7 0.3 3.5e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 GAM37115.1 - 0.011 15.4 0.1 0.016 14.9 0.1 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Acyl-CoA_dh_M PF02770.19 GAM37116.1 - 1.3e-05 25.3 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Ank_2 PF12796.7 GAM37117.1 - 2.2e-51 172.4 0.0 1.7e-09 38.2 0.0 7.7 2 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM37117.1 - 3.7e-39 128.2 7.8 0.0021 18.4 0.0 14.2 14 0 0 14 14 14 9 Ankyrin repeat Ank_4 PF13637.6 GAM37117.1 - 1.1e-38 131.1 1.0 4.4e-08 33.5 0.0 9.4 4 3 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM37117.1 - 4.4e-34 116.1 0.6 3.5e-06 27.2 0.0 10.1 5 2 5 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 GAM37117.1 - 4.9e-29 99.5 7.5 0.004 17.5 0.0 11.3 11 1 1 12 12 12 7 Ankyrin repeat PNP_UDP_1 PF01048.20 GAM37117.1 - 4e-07 29.5 3.1 1.2e-06 28.0 3.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 GAM37117.1 - 8.1e-05 22.6 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GAM37117.1 - 0.00047 20.4 0.0 0.0014 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAM37117.1 - 0.017 15.7 0.0 0.1 13.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GAM37117.1 - 0.18 12.2 0.0 0.99 9.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sugar_tr PF00083.24 GAM37121.1 - 7e-78 262.5 26.0 8.1e-78 262.3 26.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37121.1 - 2.7e-22 79.2 51.9 2.4e-20 72.8 29.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CENP-B_dimeris PF09026.10 GAM37122.1 - 0.012 16.0 10.7 0.021 15.2 10.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SDA1 PF05285.12 GAM37122.1 - 0.018 14.5 4.4 0.019 14.4 4.4 1.1 1 0 0 1 1 1 0 SDA1 PI3K_p85B PF02192.16 GAM37122.1 - 0.13 12.1 0.4 0.13 12.1 0.4 1.7 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain NOA36 PF06524.12 GAM37122.1 - 0.16 11.3 11.5 0.2 11.0 11.5 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4024 PF13216.6 GAM37122.1 - 0.23 11.4 0.3 0.42 10.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) Nop14 PF04147.12 GAM37122.1 - 0.33 9.1 9.1 0.36 9.0 9.1 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GAM37122.1 - 1.7 6.7 12.7 2.2 6.3 12.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 GAM37122.1 - 2.6 6.5 6.0 3 6.3 6.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2722 PF10846.8 GAM37122.1 - 4.8 6.0 5.9 6.1 5.7 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) AAA PF00004.29 GAM37123.1 - 1.2e-35 122.8 0.0 2.3e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 GAM37123.1 - 2.6e-17 62.6 0.9 5e-17 61.6 0.1 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 GAM37123.1 - 5.9e-06 26.3 0.0 4.9e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 GAM37123.1 - 3.7e-05 23.4 0.0 0.00023 20.9 0.0 2.2 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 GAM37123.1 - 4.4e-05 23.3 0.0 7.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAM37123.1 - 0.00027 21.3 0.1 0.046 14.1 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 GAM37123.1 - 0.00042 19.6 0.0 0.0007 18.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 GAM37123.1 - 0.0012 18.7 0.0 0.0029 17.4 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 GAM37123.1 - 0.0012 19.2 0.2 0.07 13.4 0.0 2.7 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 GAM37123.1 - 0.0018 17.5 0.1 0.0042 16.3 0.0 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 GAM37123.1 - 0.0022 18.2 0.0 0.014 15.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Bac_DnaA PF00308.18 GAM37123.1 - 0.0039 17.1 0.0 0.013 15.3 0.0 1.8 1 1 0 1 1 1 1 Bacterial dnaA protein RNA_helicase PF00910.22 GAM37123.1 - 0.0049 17.2 0.0 0.018 15.4 0.0 2.1 1 1 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 GAM37123.1 - 0.0087 16.6 0.3 0.035 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 GAM37123.1 - 0.014 14.5 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 GAM37123.1 - 0.017 15.1 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAM37123.1 - 0.019 14.6 0.1 0.11 12.0 0.0 2.0 1 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GAM37123.1 - 0.034 13.8 0.0 1.3 8.7 0.0 2.4 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 GAM37123.1 - 0.071 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM37123.1 - 0.099 12.1 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 GAM37123.1 - 0.14 12.2 0.0 0.53 10.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 GAM37123.1 - 0.29 10.9 0.0 0.29 10.9 0.0 2.7 2 1 0 2 2 1 0 AAA domain SOBP PF15279.6 GAM37123.1 - 5 7.6 6.7 7.9 7.0 6.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Asp_protease PF09668.10 GAM37124.1 - 1.7e-61 205.5 0.1 2.6e-61 204.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GAM37124.1 - 1.5e-22 80.0 0.0 2.9e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GAM37124.1 - 2.8e-11 43.9 0.0 8.1e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 GAM37124.1 - 5.1e-11 42.2 0.0 8.9e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 GAM37124.1 - 1e-07 31.7 0.0 2.8e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain RVP PF00077.20 GAM37124.1 - 0.00051 20.3 0.1 0.0017 18.6 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 GAM37124.1 - 0.00062 19.5 0.8 0.0011 18.7 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like RVP_2 PF08284.11 GAM37124.1 - 0.001 18.8 0.0 0.0023 17.7 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease CUE PF02845.16 GAM37124.1 - 0.1 12.4 0.1 5.3 6.8 0.0 2.5 2 0 0 2 2 2 0 CUE domain Acetyltransf_1 PF00583.25 GAM37125.1 - 1.4e-11 44.6 0.0 3e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM37125.1 - 5.9e-11 42.4 0.0 9e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM37125.1 - 3.6e-07 30.5 0.0 6.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM37125.1 - 0.0046 16.9 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAM37125.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM37125.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NOG1_N PF17835.1 GAM37126.1 - 1.5e-48 164.7 1.9 1.8e-48 164.6 0.1 2.1 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 GAM37126.1 - 3.1e-30 103.9 4.2 7.7e-30 102.7 4.2 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 GAM37126.1 - 3.2e-26 90.9 0.4 6.9e-26 89.8 0.4 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 GAM37126.1 - 7.4e-16 58.3 0.0 1.6e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM37126.1 - 1.6e-07 31.0 0.1 5.1e-07 29.3 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAM37126.1 - 0.0011 19.1 0.0 2 8.4 0.0 2.8 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 GAM37126.1 - 0.015 15.7 0.0 0.46 10.9 0.0 3.0 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 GAM37126.1 - 0.066 13.1 4.5 3.3 7.6 0.1 3.5 4 1 0 4 4 4 0 RsgA GTPase DUF3209 PF11483.8 GAM37126.1 - 0.11 12.9 1.0 0.58 10.6 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) Roc PF08477.13 GAM37126.1 - 0.15 12.3 0.0 0.99 9.6 0.0 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 GAM37126.1 - 2.3 8.7 0.0 2.3 8.7 0.0 2.9 2 1 1 3 3 2 0 AAA domain Leu_leader PF08054.11 GAM37128.1 - 0.26 10.9 2.2 0.47 10.1 2.2 1.4 1 0 0 1 1 1 0 Leucine operon leader peptide p450 PF00067.22 GAM37130.1 - 1.4e-67 228.4 0.0 1.7e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nucleoporin_N PF08801.11 GAM37131.1 - 2.5e-92 309.9 1.2 4.4e-92 309.1 1.2 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 GAM37131.1 - 8.4e-51 173.4 4.6 3.6e-50 171.3 1.6 2.0 2 0 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal SGL PF08450.12 GAM37131.1 - 0.02 14.5 0.0 0.24 10.9 0.0 2.5 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region ITAM PF02189.15 GAM37131.1 - 0.17 12.4 0.0 0.48 11.0 0.0 1.8 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif YqeY PF09424.10 GAM37132.1 - 9.4e-20 71.1 0.8 1.1e-19 70.9 0.8 1.0 1 0 0 1 1 1 1 Yqey-like protein tRNA_synt_1c_R1 PF04558.15 GAM37132.1 - 0.015 15.3 0.6 0.023 14.7 0.6 1.4 1 1 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Rot1 PF10681.9 GAM37133.1 - 1.9e-80 269.3 0.0 2.6e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal LSM PF01423.22 GAM37133.1 - 1.9e-10 40.2 0.1 3.1e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 GAM37133.1 - 0.0084 15.7 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 Hfq protein Xpo1 PF08389.12 GAM37134.1 - 9.8e-29 100.3 0.0 4.9e-27 94.8 0.1 3.2 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 GAM37134.1 - 4.9e-06 26.4 0.0 1.8e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 GAM37134.1 - 0.027 15.0 0.3 0.7 10.5 0.0 3.6 4 0 0 4 4 4 0 HEAT-like repeat HEAT_2 PF13646.6 GAM37134.1 - 0.06 13.8 0.0 0.84 10.1 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats TerB PF05099.13 GAM37134.1 - 0.064 13.2 1.9 0.36 10.8 0.1 2.8 3 0 0 3 3 3 0 Tellurite resistance protein TerB Fungal_trans PF04082.18 GAM37135.1 - 2.8e-51 174.1 0.0 4.5e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAM37135.1 - 7.3e-05 23.0 15.0 0.0066 16.8 4.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type EF-hand_9 PF14658.6 GAM37135.1 - 0.0001 22.5 0.0 0.0022 18.3 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_6 PF13405.6 GAM37135.1 - 0.0004 20.1 0.4 0.063 13.2 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 GAM37135.1 - 0.00049 19.5 0.1 0.22 11.1 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAM37135.1 - 0.0068 16.8 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair zf-H2C2_2 PF13465.6 GAM37135.1 - 4.7 7.8 11.2 0.96 10.0 3.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain DUF688 PF05097.12 GAM37136.1 - 0.041 13.1 0.1 0.065 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Radial_spoke PF04712.12 GAM37136.1 - 0.062 12.2 1.9 0.095 11.6 1.9 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein zinc_ribbon_12 PF11331.8 GAM37136.1 - 0.33 10.8 1.2 3.1 7.7 0.0 2.6 3 0 0 3 3 3 0 Probable zinc-ribbon domain Peptidase_M3 PF01432.20 GAM37137.1 - 5.3e-158 527.0 0.0 6.9e-158 526.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 FA_desaturase PF00487.24 GAM37138.1 - 6.6e-18 65.5 16.4 1e-17 64.9 16.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAM37138.1 - 2.6e-17 62.7 0.0 6.5e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1189 PF06691.11 GAM37138.1 - 0.13 11.8 0.3 0.33 10.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) DUF2225 PF09986.9 GAM37138.1 - 0.19 11.4 0.0 0.44 10.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Pkinase PF00069.25 GAM37139.1 - 3.6e-22 79.0 0.0 3e-21 76.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM37139.1 - 1.1e-15 57.7 0.0 3.1e-10 39.8 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase CorA PF01544.18 GAM37140.1 - 4.1e-18 65.7 3.3 4.1e-18 65.7 3.3 1.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein HhH-GPD PF00730.25 GAM37140.1 - 0.011 16.2 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein adh_short PF00106.25 GAM37141.1 - 4.2e-17 62.2 0.0 4.2e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 GAM37141.1 - 0.00016 21.7 0.0 0.00035 20.5 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAM37141.1 - 0.063 12.7 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.23 GAM37142.1 - 2.1e-18 66.4 0.2 1.6e-17 63.5 0.2 2.4 1 1 0 1 1 1 1 FAD binding domain CoA_binding_2 PF13380.6 GAM37142.1 - 0.034 14.6 0.1 0.075 13.5 0.1 1.5 1 0 0 1 1 1 0 CoA binding domain AA_permease PF00324.21 GAM37143.1 - 6.5e-40 137.1 33.3 8e-28 97.3 21.3 2.7 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 GAM37143.1 - 4.2e-20 72.0 28.6 7.8e-20 71.1 28.6 1.4 1 1 0 1 1 1 1 Amino acid permease PEX-2N PF09263.10 GAM37143.1 - 0.21 11.9 0.7 1.1 9.6 0.0 2.4 3 0 0 3 3 3 0 Peroxisome biogenesis factor 1, N-terminal RseC_MucC PF04246.12 GAM37143.1 - 3.4 7.6 11.6 6.6 6.7 4.3 3.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC PAP2 PF01569.21 GAM37144.1 - 5.2e-26 91.0 4.2 7.3e-26 90.6 1.5 2.4 2 1 0 2 2 2 1 PAP2 superfamily Xan_ur_permease PF00860.20 GAM37145.1 - 9.4e-70 235.3 30.6 3.6e-68 230.1 30.6 2.1 1 1 0 1 1 1 1 Permease family CFEM PF05730.11 GAM37146.1 - 6.5e-09 35.8 3.6 1.1e-08 35.1 3.6 1.3 1 0 0 1 1 1 1 CFEM domain AMP-binding PF00501.28 GAM37147.1 - 7.6e-82 275.1 0.0 9.6e-82 274.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM37147.1 - 3.3e-12 47.2 0.1 1.1e-11 45.5 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Rad51 PF08423.11 GAM37148.1 - 5.7e-14 52.0 0.0 1e-10 41.3 0.0 2.3 2 0 0 2 2 2 2 Rad51 ATPase PF06745.13 GAM37148.1 - 2.8e-07 30.1 0.1 6.4e-07 29.0 0.1 1.8 1 1 0 1 1 1 1 KaiC RecA PF00154.21 GAM37148.1 - 1.1e-05 25.0 0.1 3.7e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 GAM37148.1 - 3.9e-05 23.3 0.1 0.00041 20.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 GAM37148.1 - 0.0027 16.9 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DnaB_C PF03796.15 GAM37148.1 - 0.0057 16.0 0.0 0.029 13.7 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 GAM37148.1 - 0.017 14.9 0.1 0.049 13.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 GAM37148.1 - 0.061 13.8 0.2 0.22 11.9 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAM37148.1 - 0.097 13.1 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 GAM37148.1 - 0.12 12.7 0.1 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 GAM37148.1 - 0.19 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein SAP30_Sin3_bdg PF13867.6 GAM37149.1 - 2.1e-09 37.6 1.5 3.9e-09 36.7 0.2 1.9 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-H2C2_2 PF13465.6 GAM37150.1 - 1e-07 32.0 20.4 5.8e-05 23.3 3.3 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 GAM37150.1 - 1.9e-05 24.8 14.0 0.00078 19.8 4.5 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM37150.1 - 0.036 14.9 20.3 0.054 14.3 3.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAM37150.1 - 0.048 14.0 0.2 0.12 12.6 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 GAM37150.1 - 0.055 14.1 1.4 0.16 12.6 0.2 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 GAM37150.1 - 0.14 12.2 0.8 9.2 6.4 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger BRO1 PF03097.18 GAM37151.1 - 4e-135 450.6 4.3 4e-135 450.6 4.3 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 GAM37151.1 - 3e-82 276.3 15.6 3e-82 276.3 15.6 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF3012 PF11216.8 GAM37151.1 - 0.32 11.1 1.0 17 5.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) GAS PF13851.6 GAM37151.1 - 0.89 8.9 14.2 2.4 7.5 0.1 3.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Ribosomal_S20p PF01649.18 GAM37151.1 - 1.8 9.2 4.6 23 5.7 1.7 3.5 3 0 0 3 3 3 0 Ribosomal protein S20 DnaJ_C PF01556.18 GAM37152.1 - 5.3e-35 120.7 0.0 7.8e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAM37152.1 - 2.1e-21 75.8 1.7 4.3e-21 74.8 1.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAM37152.1 - 5e-10 39.6 19.5 1.2e-09 38.4 19.5 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 GAM37152.1 - 0.0026 17.7 3.0 0.0026 17.7 3.0 3.0 1 1 1 2 2 2 1 Tryptophan RNA-binding attenuator protein inhibitory protein Lon_C PF05362.13 GAM37153.1 - 8.6e-62 208.3 0.0 1.5e-61 207.5 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 GAM37153.1 - 4.7e-36 124.6 0.0 1.1e-35 123.5 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 GAM37153.1 - 1.1e-21 77.7 0.0 2.3e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAM37153.1 - 1.8e-07 31.2 0.0 3.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 GAM37153.1 - 4.7e-06 25.8 0.3 9.6e-06 24.7 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_2 PF07724.14 GAM37153.1 - 5.1e-06 26.7 0.0 1.5e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAM37153.1 - 1.1e-05 25.7 0.1 0.00013 22.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain ChlI PF13541.6 GAM37153.1 - 3.6e-05 23.6 0.0 0.00011 22.1 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 GAM37153.1 - 0.00014 22.2 1.2 0.00074 19.9 0.1 2.5 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 GAM37153.1 - 0.00018 21.3 0.0 0.00053 19.8 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAM37153.1 - 0.0025 18.4 0.4 0.027 15.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 GAM37153.1 - 0.0054 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 GAM37153.1 - 0.018 15.0 0.1 0.56 10.1 0.0 3.0 2 1 1 3 3 3 0 NTPase IstB_IS21 PF01695.17 GAM37153.1 - 0.019 14.7 0.1 0.075 12.8 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 GAM37153.1 - 0.026 14.3 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAM37153.1 - 0.052 13.9 0.0 0.22 11.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Apt1 PF10351.9 GAM37153.1 - 0.058 12.3 4.1 0.14 11.0 4.1 1.6 1 0 0 1 1 1 0 Golgi-body localisation protein domain RsgA_GTPase PF03193.16 GAM37153.1 - 0.085 12.8 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 GAM37153.1 - 0.11 13.0 0.9 0.44 11.1 0.1 2.4 2 1 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 GAM37153.1 - 0.13 11.7 0.1 0.35 10.4 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region DNTTIP1_dimer PF18192.1 GAM37153.1 - 0.63 10.4 2.1 35 4.8 0.3 3.2 3 0 0 3 3 2 0 DNTTIP1 dimerisation domain Presenilin PF01080.17 GAM37153.1 - 8.8 5.0 8.3 15 4.2 8.3 1.3 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 GAM37154.1 - 4.1e-10 39.5 0.0 1.1e-08 34.7 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM37154.1 - 1.8e-09 37.3 0.0 2.7e-08 33.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase NmrA PF05368.13 GAM37155.1 - 1e-13 51.4 0.0 1.5e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM37155.1 - 2.6e-13 50.3 0.0 4.4e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Biotin_carb_N PF00289.22 GAM37155.1 - 0.039 14.5 0.0 0.066 13.8 0.0 1.4 1 0 0 1 1 1 0 Biotin carboxylase, N-terminal domain Semialdhyde_dh PF01118.24 GAM37155.1 - 0.053 13.9 0.3 0.099 13.1 0.3 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 GAM37155.1 - 0.074 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 GAM37155.1 - 0.11 12.6 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pigment_DH PF06324.11 GAM37155.1 - 0.17 12.0 1.1 1.3 9.3 0.2 2.6 2 0 0 2 2 2 0 Pigment-dispersing hormone (PDH) Amidohydro_1 PF01979.20 GAM37156.1 - 1e-54 186.2 0.0 1.2e-54 185.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM37156.1 - 1.6e-13 51.0 2.8 9.7e-10 38.5 0.0 2.9 2 1 0 3 3 3 2 Amidohydrolase family A_deaminase PF00962.22 GAM37156.1 - 0.094 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase Cep3 PF16846.5 GAM37157.1 - 2.3e-06 26.4 0.0 1.1e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit B Fungal_trans PF04082.18 GAM37157.1 - 8.2e-06 25.0 0.1 1.3e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM37157.1 - 3.2e-05 24.0 12.6 5.8e-05 23.1 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dor1 PF04124.12 GAM37157.1 - 0.0039 15.9 0.2 0.91 8.1 0.0 2.2 2 0 0 2 2 2 2 Dor1-like family HALZ PF02183.18 GAM37157.1 - 0.035 14.3 0.2 0.068 13.4 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper IFP_35_N PF07334.13 GAM37157.1 - 0.058 13.5 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF1479 PF07350.12 GAM37158.1 - 2.4e-96 323.1 0.0 3.2e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Sugar_tr PF00083.24 GAM37159.1 - 5.9e-85 285.8 19.2 6.8e-85 285.6 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37159.1 - 7.9e-30 104.0 29.6 9.6e-25 87.2 7.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM37159.1 - 3.5e-09 35.7 1.8 6.2e-09 34.8 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 GAM37159.1 - 1.7e-07 30.9 3.1 1.7e-07 30.9 3.1 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB CorA PF01544.18 GAM37160.1 - 2.5e-11 43.4 0.5 4.5e-11 42.6 0.5 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 GAM37160.1 - 0.026 13.3 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AMP-binding PF00501.28 GAM37161.1 - 4.6e-53 180.3 0.0 6.1e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 GAM37161.1 - 9.8e-08 32.3 0.3 2.4e-07 31.0 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF963 PF06131.11 GAM37161.1 - 0.16 11.4 0.8 0.46 9.9 0.8 1.8 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) adh_short PF00106.25 GAM37162.1 - 1.2e-25 90.1 0.1 1.4e-24 86.6 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37162.1 - 1.2e-18 67.6 0.1 7.8e-18 64.9 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM37162.1 - 9.3e-06 25.7 0.2 1.4e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM37162.1 - 0.00049 19.6 0.1 0.00069 19.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM37162.1 - 0.024 13.8 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAM37162.1 - 0.21 11.0 0.1 0.28 10.5 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Mob1_phocein PF03637.17 GAM37163.1 - 1.2e-25 90.5 0.1 2e-25 89.8 0.1 1.3 1 0 0 1 1 1 1 Mob1/phocein family Coilin_N PF15862.5 GAM37163.1 - 0.0044 16.8 4.4 0.26 11.1 0.0 2.5 1 1 1 2 2 2 1 Coilin N-terminus ALMT PF11744.8 GAM37163.1 - 7.6 5.2 11.2 10 4.8 11.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter cobW PF02492.19 GAM37164.1 - 6.5e-44 149.6 0.1 9.9e-44 149.0 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain HIT PF01230.23 GAM37164.1 - 6.8e-24 84.5 0.0 1.5e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 HIT domain RsgA_GTPase PF03193.16 GAM37164.1 - 0.00011 22.1 0.1 0.34 10.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase DcpS_C PF11969.8 GAM37164.1 - 0.00014 22.4 0.0 0.00026 21.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Septin PF00735.18 GAM37164.1 - 0.0093 15.3 0.2 2.5 7.3 0.0 2.3 2 0 0 2 2 2 2 Septin MeaB PF03308.16 GAM37164.1 - 0.011 14.8 0.2 3 6.7 0.0 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAM37164.1 - 0.015 15.7 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 GAM37164.1 - 0.027 15.0 0.0 0.074 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Holin_BhlA PF10960.8 GAM37164.1 - 0.028 14.4 0.1 5 7.2 0.0 2.5 2 0 0 2 2 2 0 BhlA holin family TsaE PF02367.17 GAM37164.1 - 0.028 14.4 0.1 0.077 13.0 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 GAM37164.1 - 0.038 13.1 0.1 0.071 12.2 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 GAM37164.1 - 0.064 13.3 0.5 0.13 12.4 0.1 1.9 2 1 0 2 2 1 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 GAM37164.1 - 0.073 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 GAM37164.1 - 0.1 13.1 0.4 0.4 11.2 0.1 2.1 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 GAM37164.1 - 0.12 12.6 0.1 0.33 11.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.6 GAM37164.1 - 0.13 12.0 1.0 0.29 10.9 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain HD_3 PF13023.6 GAM37165.1 - 1.7e-48 164.7 0.2 2.1e-48 164.4 0.2 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 GAM37165.1 - 3.2e-14 53.1 0.1 4e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HAUS6_N PF14661.6 GAM37166.1 - 1.3e-36 126.3 0.8 1.3e-36 126.3 0.8 1.6 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Sec2p PF06428.11 GAM37166.1 - 5.2 7.1 6.8 2.1 8.4 0.1 2.9 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p Rad4 PF03835.15 GAM37167.1 - 7.9e-36 122.9 0.5 2.5e-35 121.3 0.5 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 GAM37167.1 - 2.2e-29 101.7 0.5 4.4e-29 100.7 0.5 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 GAM37167.1 - 2.8e-15 55.9 0.1 5.8e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 GAM37167.1 - 3.7e-13 50.2 0.2 3.7e-13 50.2 0.2 3.6 5 1 0 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 GAM37167.1 - 0.00028 21.3 0.0 0.0016 18.9 0.0 2.3 2 0 0 2 2 2 1 Transglutaminase-like superfamily Seryl_tRNA_N PF02403.22 GAM37167.1 - 0.94 9.7 5.2 0.72 10.1 0.3 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain p450 PF00067.22 GAM37168.1 - 1.5e-19 70.1 0.0 1.7e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 GAM37168.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.3 1 1 0 1 1 1 0 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37168.1 - 0.034 13.7 0.0 0.053 13.1 0.0 1.4 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.16 GAM37169.1 - 5.7e-34 117.6 62.7 1.3e-33 116.4 55.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily PALP PF00291.25 GAM37170.1 - 2.1e-57 194.8 1.0 2.4e-57 194.6 1.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ank_2 PF12796.7 GAM37172.1 - 1.8e-41 140.6 0.2 1.8e-15 57.3 0.0 5.4 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM37172.1 - 3.5e-41 139.1 5.1 9.7e-14 51.6 0.0 8.7 5 3 4 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM37172.1 - 1.2e-40 132.9 5.5 1.1e-06 28.4 0.0 9.7 10 0 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 GAM37172.1 - 1.2e-36 123.5 7.8 7.9e-07 29.3 0.0 9.5 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 GAM37172.1 - 1.8e-33 114.2 7.9 9.1e-06 25.9 0.0 8.4 6 2 2 8 8 8 7 Ankyrin repeats (many copies) Peptidase_M16 PF00675.20 GAM37172.1 - 0.013 15.5 0.0 0.043 13.8 0.0 1.8 1 1 1 2 2 2 0 Insulinase (Peptidase family M16) Asp PF00026.23 GAM37173.1 - 1.4e-44 152.8 0.1 1.7e-44 152.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM37173.1 - 1.8e-05 25.0 0.3 0.00022 21.5 0.3 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAM37173.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Peptidase_S15 PF02129.18 GAM37174.1 - 7.6e-48 163.4 1.0 9.8e-48 163.1 1.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 GAM37174.1 - 1.9e-32 113.0 0.1 8.8e-32 110.9 0.1 1.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain PT-TG PF14449.6 GAM37175.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Pre-toxin TG CoA_binding_2 PF13380.6 GAM37176.1 - 1.2e-28 100.0 0.1 1.4e-26 93.2 0.0 2.4 2 0 0 2 2 2 1 CoA binding domain NAD_binding_8 PF13450.6 GAM37176.1 - 1.2e-14 54.3 0.0 4e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAM37176.1 - 9.6e-06 25.1 0.0 0.00097 18.5 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 GAM37176.1 - 0.00025 20.4 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM37176.1 - 0.00032 20.4 0.0 0.0054 16.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DUF624 PF04854.14 GAM37176.1 - 0.073 13.2 0.8 3.1 8.0 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function, DUF624 Trp_halogenase PF04820.14 GAM37176.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 GAM37176.1 - 0.14 12.2 0.1 7.3 6.6 0.0 2.7 2 1 1 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GAM37176.1 - 0.17 11.1 0.1 0.38 10.0 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 GAM37176.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain RrnaAD PF00398.20 GAM37179.1 - 1.2e-57 195.0 0.0 1.6e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 GAM37179.1 - 0.00019 22.1 0.0 0.00049 20.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM37179.1 - 0.0002 21.9 0.0 0.00061 20.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM37179.1 - 0.064 14.0 0.0 0.15 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FA_hydroxylase PF04116.13 GAM37181.1 - 1.8e-21 76.8 13.3 1.8e-21 76.8 13.3 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.16 GAM37182.1 - 5.2e-21 75.0 35.8 1.7e-13 50.3 18.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM37182.1 - 8.4e-17 61.2 18.3 2.4e-16 59.6 18.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter HRI1 PF16815.5 GAM37183.1 - 6.4e-24 84.9 0.2 1e-23 84.3 0.2 1.4 1 1 0 1 1 1 1 Protein HRI1 Zn_clus PF00172.18 GAM37184.1 - 3e-05 24.1 8.6 3e-05 24.1 8.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM37184.1 - 0.0027 16.8 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 GAM37185.1 - 9.3e-19 67.6 30.3 6.2e-12 45.1 15.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N_2 PF13602.6 GAM37187.1 - 5.9e-11 43.5 0.0 1.2e-10 42.6 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAM37187.1 - 8.8e-10 38.7 0.0 1.8e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM37187.1 - 3.8e-05 23.5 0.2 0.00013 21.8 0.2 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 GAM37187.1 - 0.065 12.5 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ABM PF03992.16 GAM37190.1 - 0.019 15.1 0.2 1.1 9.5 0.0 2.7 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase PEP_mutase PF13714.6 GAM37191.1 - 9.5e-46 156.2 0.0 1.1e-45 156.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 GAM37191.1 - 1.3e-17 63.5 0.0 1.6e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 GAM37191.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.5 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase Aconitase PF00330.20 GAM37192.1 - 1.4e-73 248.5 0.0 4.5e-72 243.5 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAM37192.1 - 5e-16 59.2 0.0 9.6e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Fungal_trans PF04082.18 GAM37192.1 - 0.0056 15.7 1.9 0.011 14.8 1.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2397 PF09660.10 GAM37192.1 - 0.18 10.7 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Cys_Met_Meta_PP PF01053.20 GAM37193.1 - 2.3e-98 329.2 0.0 2.9e-98 328.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MFS_1 PF07690.16 GAM37193.1 - 7.6e-29 100.7 35.9 1.1e-28 100.2 35.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DegT_DnrJ_EryC1 PF01041.17 GAM37193.1 - 8.5e-06 25.3 1.2 1.6e-05 24.4 1.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 GAM37193.1 - 5.7e-05 22.2 0.1 9.3e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAM37193.1 - 0.00024 20.5 0.2 0.00088 18.6 0.2 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase GDC-P PF02347.16 GAM37193.1 - 0.0022 16.9 0.2 0.0047 15.8 0.1 1.5 2 0 0 2 2 2 1 Glycine cleavage system P-protein DAO PF01266.24 GAM37194.1 - 1.5e-28 100.4 0.0 5.6e-15 55.8 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Abhydrolase_3 PF07859.13 GAM37195.1 - 1.3e-44 152.6 0.0 1.6e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAM37195.1 - 1.4e-06 27.5 0.1 4.1e-06 26.0 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 GAM37195.1 - 0.0012 18.4 0.0 0.0037 16.8 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Glyco_trans_2_3 PF13632.6 GAM37196.1 - 5.4e-53 179.9 2.6 5.4e-53 179.9 2.6 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAM37196.1 - 0.009 15.8 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_hydro_cc PF11790.8 GAM37197.1 - 9.8e-77 257.7 0.7 1.6e-76 257.0 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_16 PF00722.21 GAM37197.1 - 1.4e-16 60.5 0.5 2.7e-16 59.5 0.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sugar_tr PF00083.24 GAM37198.1 - 9e-66 222.6 22.5 1.1e-65 222.3 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37198.1 - 7e-17 61.4 25.9 7e-17 61.4 25.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.6 GAM37199.1 - 1.4e-35 122.6 0.0 5.3e-32 111.0 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM37199.1 - 8.4e-13 48.7 0.0 2.1e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.7 GAM37199.1 - 1.8e-10 41.8 0.0 3.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM37199.1 - 4.3e-05 23.3 0.0 8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAM37199.1 - 0.00018 21.4 0.1 0.073 12.9 0.0 3.0 4 0 0 4 4 4 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 GAM37199.1 - 0.00023 20.5 0.0 0.0067 15.7 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 GAM37199.1 - 0.051 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 GAM37199.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 GAM37199.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 GAM37199.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase NTP_transf_9 PF04248.12 GAM37200.1 - 1.7e-15 56.7 0.8 3.9e-05 23.4 0.1 3.6 2 1 1 3 3 3 3 Domain of unknown function (DUF427) Gly_transf_sug PF04488.15 GAM37200.1 - 4.5e-12 46.4 0.0 1.6e-11 44.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif NHL PF01436.21 GAM37201.1 - 0.23 11.6 4.4 0.58 10.3 0.1 3.6 3 1 1 4 4 4 0 NHL repeat UbiA PF01040.18 GAM37202.1 - 7.1e-20 71.4 14.3 1.5e-19 70.3 14.3 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family Tenui_PVC2 PF06656.11 GAM37202.1 - 0.053 11.4 0.0 0.08 10.8 0.0 1.2 1 0 0 1 1 1 0 Tenuivirus PVC2 protein Zn_clus PF00172.18 GAM37203.1 - 6.5e-08 32.6 11.2 1.1e-07 31.8 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fasciclin PF02469.22 GAM37204.1 - 5.5e-46 155.9 4.8 2.7e-26 92.3 0.2 2.1 2 0 0 2 2 2 2 Fasciclin domain MFS_1 PF07690.16 GAM37206.1 - 3.1e-11 42.8 50.0 4.6e-07 29.1 35.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_4 PF08386.10 GAM37207.1 - 8.2e-25 86.9 0.0 2.1e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 GAM37207.1 - 3.6e-13 49.8 0.0 1.9e-07 31.0 0.0 3.4 2 1 1 3 3 3 2 alpha/beta hydrolase fold DUF2551 PF10826.8 GAM37208.1 - 0.029 14.6 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) FAD_binding_3 PF01494.19 GAM37209.1 - 5.2e-23 81.8 1.5 1.5e-16 60.6 0.4 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAM37209.1 - 0.00025 21.2 0.0 0.00057 20.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAM37209.1 - 0.00045 19.4 0.2 0.00092 18.4 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAM37209.1 - 0.0043 16.4 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM37209.1 - 0.0071 15.6 0.2 0.021 14.0 0.0 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM37209.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 GAM37209.1 - 0.017 15.7 0.1 0.06 13.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM37209.1 - 0.042 13.1 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 GAM37209.1 - 0.058 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Rop-like PF05082.13 GAM37210.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Rop-like PEP_mutase PF13714.6 GAM37211.1 - 5.8e-56 189.6 0.3 7e-56 189.3 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 GAM37211.1 - 2.8e-13 49.2 0.3 3.7e-13 48.8 0.3 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 GAM37211.1 - 2.3e-05 23.9 0.0 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase AA_permease PF00324.21 GAM37212.1 - 4.8e-105 351.9 39.1 5.5e-105 351.7 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM37212.1 - 2e-22 79.6 44.5 2.4e-22 79.4 44.5 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_11 PF00457.17 GAM37213.1 - 4.3e-77 257.8 19.3 5.1e-77 257.5 19.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 p450 PF00067.22 GAM37214.1 - 1.5e-73 248.1 0.0 1.9e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CpxA_peri PF16527.5 GAM37214.1 - 0.0087 16.4 0.1 0.017 15.5 0.1 1.4 1 0 0 1 1 1 1 Two-component sensor protein CpxA, periplasmic domain NmrA PF05368.13 GAM37215.1 - 6.9e-22 78.1 0.0 8.4e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM37215.1 - 1e-07 32.0 0.0 6e-07 29.5 0.0 2.1 3 0 0 3 3 3 1 NAD(P)H-binding SKI PF01202.22 GAM37217.1 - 8.4e-13 48.7 0.0 1.3e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.11 GAM37218.1 - 7.9e-17 61.3 0.0 1.4e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 GAM37218.1 - 0.051 13.6 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Shikimate_dh_N PF08501.11 GAM37219.1 - 4.2e-18 65.4 0.0 8.4e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 GAM37219.1 - 3.6e-05 23.8 0.0 5.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAM37219.1 - 0.04 14.2 0.0 0.19 12.0 0.0 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain OCD_Mu_crystall PF02423.15 GAM37219.1 - 0.046 12.6 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Sugar_tr PF00083.24 GAM37220.1 - 3.9e-97 326.0 18.8 4.4e-97 325.8 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37220.1 - 8.3e-21 74.3 27.8 1.4e-20 73.6 27.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily SnoaL_4 PF13577.6 GAM37221.1 - 6.1e-08 32.8 0.3 8.8e-08 32.3 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 GAM37221.1 - 0.003 17.9 0.2 0.0045 17.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 GAM37221.1 - 0.058 13.7 0.6 0.08 13.2 0.6 1.2 1 0 0 1 1 1 0 SnoaL-like domain DHquinase_I PF01487.15 GAM37222.1 - 1.4e-44 153.1 0.0 2e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 GAM37222.1 - 2.3e-24 85.5 0.0 4.8e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 GAM37222.1 - 4.1e-09 36.6 0.0 1.1e-08 35.2 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 GAM37222.1 - 4e-08 32.9 0.1 3.2e-07 30.0 0.1 2.7 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 GAM37222.1 - 0.023 15.0 0.1 0.37 11.0 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 GAM37222.1 - 0.14 11.6 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_2 PF03446.15 GAM37222.1 - 0.18 11.9 0.1 0.35 11.0 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DHquinase_II PF01220.19 GAM37223.1 - 1.4e-59 199.7 0.8 1.6e-59 199.5 0.8 1.0 1 0 0 1 1 1 1 Dehydroquinase class II AP_endonuc_2 PF01261.24 GAM37224.1 - 2.3e-29 102.4 0.0 3e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Phytase-like PF13449.6 GAM37225.1 - 2.9e-39 135.7 0.0 4.1e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Esterase-like activity of phytase Pkinase PF00069.25 GAM37226.1 - 1.3e-16 60.8 0.0 1.5e-15 57.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM37226.1 - 0.022 14.1 0.1 0.89 8.8 0.1 2.1 1 1 0 1 1 1 0 Protein tyrosine kinase NAD_binding_8 PF13450.6 GAM37227.1 - 8.7e-13 48.3 0.2 1.7e-12 47.4 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAM37227.1 - 3e-09 36.7 0.0 1.9e-07 30.7 0.0 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 GAM37227.1 - 2.9e-05 23.6 0.2 5.5e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM37227.1 - 0.00082 19.9 0.3 0.0024 18.4 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM37227.1 - 0.0015 17.7 0.6 0.0024 17.0 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM37227.1 - 0.0017 18.0 1.0 0.0069 16.0 0.7 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAM37227.1 - 0.0028 16.9 0.5 0.008 15.4 0.3 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 GAM37227.1 - 0.0029 16.4 0.5 0.0044 15.8 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAM37227.1 - 0.018 14.2 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_C48 PF02902.19 GAM37228.1 - 0.00035 20.5 0.0 0.00054 19.9 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MIP PF00230.20 GAM37229.1 - 1.8e-34 119.4 5.7 2.8e-34 118.8 5.7 1.2 1 0 0 1 1 1 1 Major intrinsic protein Abhydrolase_3 PF07859.13 GAM37230.1 - 1.9e-16 60.5 0.0 4.7e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM37230.1 - 2.8e-08 33.5 0.0 0.0043 16.5 0.0 2.3 2 1 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 GAM37230.1 - 7e-07 28.4 0.0 9.2e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S15 PF02129.18 GAM37230.1 - 2.6e-05 23.9 0.0 7.1e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase PF07224.11 GAM37230.1 - 6.9e-05 22.0 0.0 9.6e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase AXE1 PF05448.12 GAM37230.1 - 9.4e-05 21.2 0.0 0.016 13.9 0.0 2.1 1 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Esterase PF00756.20 GAM37230.1 - 0.00011 22.0 0.1 0.0027 17.4 0.1 2.1 1 1 0 1 1 1 1 Putative esterase COesterase PF00135.28 GAM37230.1 - 0.00013 21.0 0.0 0.00026 20.0 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family Esterase_phd PF10503.9 GAM37230.1 - 0.0016 17.9 0.1 0.57 9.6 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Glyco_hydro_10 PF00331.20 GAM37231.1 - 1.2e-102 343.3 0.1 1.4e-102 343.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 GAM37231.1 - 3.3e-14 52.5 7.9 3.3e-14 52.5 7.9 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 GAM37231.1 - 0.19 12.0 2.3 0.38 11.0 2.3 1.5 1 0 0 1 1 1 0 Toxin 7 Sporozoite_P67 PF05642.11 GAM37231.1 - 0.42 8.7 6.4 0.56 8.2 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MFS_1 PF07690.16 GAM37232.1 - 2.7e-19 69.3 37.4 7.6e-18 64.5 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rhodanese PF00581.20 GAM37233.1 - 1.1e-12 48.3 0.0 2.2e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Pyr_redox_dim PF02852.22 GAM37233.1 - 7.1e-10 39.1 0.0 1.3e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.14 GAM37233.1 - 1.1e-09 37.9 0.0 2.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 GAM37235.1 - 0.00032 19.8 13.7 0.00032 19.8 13.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM37236.1 - 4.2e-89 299.5 21.5 5.1e-89 299.2 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37236.1 - 6.5e-30 104.2 22.4 9.3e-30 103.7 22.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 GAM37236.1 - 0.0099 14.2 12.7 0.087 11.1 1.1 3.1 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 GAM37236.1 - 0.059 12.2 13.4 0.28 10.0 3.0 3.2 2 2 1 3 3 3 0 MFS_1 like family YtpI PF14007.6 GAM37236.1 - 9.4 6.5 14.4 0.048 13.8 1.9 3.2 4 0 0 4 4 4 0 YtpI-like protein ArAE_2_N PF10337.9 GAM37237.1 - 4.3e-25 88.7 19.3 4.5e-24 85.3 6.7 4.2 3 1 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 GAM37237.1 - 1.5e-18 67.1 10.9 1.5e-18 67.1 10.9 2.6 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 GAM37237.1 - 6.8e-08 32.6 2.3 1.4e-05 25.1 0.2 3.3 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 DUF2798 PF11391.8 GAM37237.1 - 0.0052 16.8 1.9 0.0052 16.8 1.9 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2798) ECH_1 PF00378.20 GAM37238.1 - 9e-31 107.1 0.4 4.4e-23 81.9 0.3 2.3 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase NmrA PF05368.13 GAM37238.1 - 1.8e-15 57.1 0.0 2.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family ECH_2 PF16113.5 GAM37238.1 - 1.1e-10 41.5 0.7 1.1e-09 38.3 0.6 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Epimerase PF01370.21 GAM37238.1 - 0.015 14.7 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM37238.1 - 0.1 12.5 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 GAM37239.1 - 2.5e-31 109.0 0.0 2.9e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM37239.1 - 2.8e-09 37.1 0.0 4.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM37239.1 - 0.00093 18.7 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAM37239.1 - 0.0066 16.7 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 GAM37239.1 - 0.049 13.5 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 GAM37240.1 - 2.2e-35 121.9 0.0 3.6e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37240.1 - 7.8e-24 84.5 0.0 1.2e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Zn_clus PF00172.18 GAM37240.1 - 3.5e-09 36.6 12.1 5.8e-09 35.9 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1776 PF08643.10 GAM37240.1 - 1e-05 25.1 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Fungal_trans PF04082.18 GAM37240.1 - 5.7e-05 22.3 0.0 8.5e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.21 GAM37241.1 - 2.9e-09 36.8 0.0 1.3e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM37241.1 - 5.8e-06 26.3 0.0 2.2e-05 24.4 0.0 1.9 2 1 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAM37241.1 - 8.8e-06 24.9 0.0 1.6e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 GAM37241.1 - 2.2e-05 24.1 0.0 0.004 16.7 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family RmlD_sub_bind PF04321.17 GAM37241.1 - 0.0004 19.6 0.0 0.0012 18.0 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Semialdhyde_dh PF01118.24 GAM37241.1 - 0.001 19.5 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 GAM37241.1 - 0.003 17.0 0.0 0.42 9.9 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase KR PF08659.10 GAM37241.1 - 0.0043 17.0 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 GAM37241.1 - 0.0094 15.1 0.0 0.23 10.6 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Shikimate_DH PF01488.20 GAM37241.1 - 0.033 14.3 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 GAM37241.1 - 0.041 13.3 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.20 GAM37241.1 - 0.097 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDPD_2 PF13653.6 GAM37242.1 - 0.0025 18.2 1.0 0.0047 17.3 1.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 GAM37246.1 - 1.5e-91 301.1 0.0 3.2e-16 59.7 0.0 6.9 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM37246.1 - 3.3e-63 209.3 0.1 3.6e-09 37.0 0.0 7.8 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 GAM37246.1 - 3.7e-61 201.0 0.0 9.9e-06 25.8 0.0 13.5 14 0 0 14 14 14 10 Ankyrin repeat Ank_3 PF13606.6 GAM37246.1 - 1.5e-51 166.4 0.0 0.0014 18.9 0.0 13.1 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 GAM37246.1 - 6.5e-46 153.8 0.0 5e-06 26.7 0.0 8.9 3 3 5 9 9 9 9 Ankyrin repeats (many copies) Cthe_2159 PF14262.6 GAM37246.1 - 0.0013 18.1 0.4 10 5.4 0.0 4.0 2 1 1 4 4 4 1 Carbohydrate-binding domain-containing protein Cthe_2159 F-box-like PF12937.7 GAM37246.1 - 0.0034 17.2 0.1 0.006 16.5 0.1 1.4 1 0 0 1 1 1 1 F-box-like BLACT_WH PF17778.1 GAM37246.1 - 2.5 8.2 6.5 15 5.7 0.7 4.6 5 1 1 6 6 6 0 Beta-lactamase associated winged helix domain VWA_3_C PF18571.1 GAM37246.1 - 3.3 7.7 14.5 5.6 6.9 0.1 6.9 8 0 0 8 8 8 0 von Willebrand factor type A C-terminal domain COesterase PF00135.28 GAM37247.1 - 1.3e-87 294.9 0.0 1.6e-87 294.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM37247.1 - 7.5e-09 35.7 0.2 3.5e-08 33.6 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM37247.1 - 0.0051 16.3 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Myb_DNA-binding PF00249.31 GAM37248.1 - 0.025 14.8 0.1 0.53 10.5 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain PEX-2N PF09263.10 GAM37249.1 - 0.00075 19.8 0.8 49 4.3 0.0 4.4 4 0 0 4 4 4 2 Peroxisome biogenesis factor 1, N-terminal DUF4096 PF13340.6 GAM37249.1 - 0.0067 16.6 3.8 80 3.6 0.1 4.5 4 0 0 4 4 4 0 Putative transposase of IS4/5 family (DUF4096) GIY-YIG PF01541.24 GAM37249.1 - 0.23 11.8 1.8 0.91 9.8 0.1 3.0 2 1 0 2 2 2 0 GIY-YIG catalytic domain DUF3328 PF11807.8 GAM37250.1 - 1.1e-26 93.9 0.0 1.6e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 GAM37251.1 - 6.7e-15 55.5 0.1 9.9e-15 54.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) 2OG-FeII_Oxy_3 PF13640.6 GAM37252.1 - 8.8e-08 32.9 0.0 1.9e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aldolase_II PF00596.21 GAM37254.1 - 2.8e-48 164.3 0.1 3.4e-48 164.0 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TetR_N PF00440.23 GAM37254.1 - 0.049 13.4 0.4 0.51 10.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Cyclase PF04199.13 GAM37255.1 - 4e-13 49.8 0.0 5.5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Anillin_N PF16018.5 GAM37256.1 - 0.055 14.1 0.0 0.14 12.8 0.0 1.6 2 0 0 2 2 2 0 Anillin N-terminus F_bP_aldolase PF01116.20 GAM37257.1 - 9.3e-91 304.2 0.0 1e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II EAL PF00563.20 GAM37257.1 - 0.04 13.4 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 EAL domain adh_short_C2 PF13561.6 GAM37258.1 - 2.8e-60 203.8 0.6 3.4e-60 203.5 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM37258.1 - 4e-45 153.7 0.5 4.7e-45 153.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM37258.1 - 0.0012 18.8 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 KR domain SWIRM-assoc_3 PF16498.5 GAM37258.1 - 0.12 12.6 0.2 0.3 11.4 0.2 1.6 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal adh_short PF00106.25 GAM37259.1 - 2.5e-37 128.3 0.0 3.5e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37259.1 - 6.9e-24 84.7 0.0 8.9e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 GAM37259.1 - 0.12 12.4 0.3 0.22 11.5 0.3 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase CBM_19 PF03427.13 GAM37260.1 - 1.3e-11 44.3 19.1 1.3e-11 44.3 19.1 2.8 1 1 1 2 2 2 1 Carbohydrate binding domain (family 19) Dicty_REP PF05086.12 GAM37260.1 - 0.26 9.2 6.2 0.35 8.8 6.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RPE65 PF03055.15 GAM37261.1 - 3.6e-96 323.2 0.0 4.4e-96 322.9 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein AAA_29 PF13555.6 GAM37261.1 - 0.083 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PHP_C PF13263.6 GAM37263.1 - 0.0013 18.5 0.1 0.0027 17.4 0.1 1.5 1 0 0 1 1 1 1 PHP-associated p450 PF00067.22 GAM37264.1 - 7.2e-48 163.5 0.0 9e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 GAM37265.1 - 7.4e-42 143.5 0.1 1.5e-41 142.5 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM37265.1 - 1.4e-36 125.8 0.0 2.9e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM37265.1 - 2.2e-12 47.3 0.9 4.7e-11 42.9 0.2 2.1 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GAM37265.1 - 5.4e-05 22.5 0.2 7.5e-05 22.0 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 GAM37265.1 - 0.0018 18.2 0.6 0.0027 17.6 0.2 1.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 GAM37265.1 - 0.0027 17.2 0.6 0.015 14.8 0.6 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 GAM37265.1 - 0.0031 16.8 0.1 0.0045 16.3 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 GAM37265.1 - 0.008 15.6 0.5 0.011 15.1 0.1 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase AlaDh_PNT_C PF01262.21 GAM37265.1 - 0.024 13.9 0.1 0.04 13.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 GAM37265.1 - 0.031 14.7 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 GAM37265.1 - 0.1 12.9 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1776 PF08643.10 GAM37265.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Amidohydro_1 PF01979.20 GAM37266.1 - 1.1e-21 77.6 0.0 5.1e-21 75.4 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM37266.1 - 6e-11 42.5 0.0 1.1e-07 31.7 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.16 GAM37267.1 - 6.8e-33 114.0 32.2 1.2e-32 113.2 32.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily AAT PF03417.16 GAM37267.1 - 3.5e-27 95.6 0.0 5.8e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF2198 PF09964.9 GAM37267.1 - 0.048 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2198) Transp_cyt_pur PF02133.15 GAM37268.1 - 9.2e-85 285.0 49.0 1.2e-84 284.7 49.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Lipase_GDSL PF00657.22 GAM37268.1 - 6e-05 23.1 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAM37268.1 - 0.077 13.4 0.6 0.54 10.6 0.6 2.1 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Cys_Met_Meta_PP PF01053.20 GAM37269.1 - 2.6e-30 105.2 0.0 3.4e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAM37269.1 - 0.0021 17.3 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.16 GAM37270.1 - 4.9e-39 134.3 57.0 2.9e-38 131.7 57.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM37270.1 - 5.1e-15 54.9 34.0 1.3e-14 53.6 34.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CBM_1 PF00734.18 GAM37271.1 - 1.1e-14 54.0 10.6 1.1e-14 54.0 10.6 2.8 3 1 0 3 3 3 1 Fungal cellulose binding domain DPBB_1 PF03330.18 GAM37271.1 - 8e-07 29.3 0.5 8e-07 29.3 0.5 2.3 2 0 0 2 2 2 1 Lytic transglycolase MFS_1 PF07690.16 GAM37272.1 - 5e-46 157.3 45.9 1.4e-45 155.7 45.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM37272.1 - 1.4e-13 50.2 20.5 2.2e-13 49.5 20.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SelK_SelG PF10961.8 GAM37272.1 - 0.54 10.9 3.0 3.9 8.2 0.1 3.5 4 0 0 4 4 4 0 Selenoprotein SelK_SelG MFS_1 PF07690.16 GAM37273.1 - 2.8e-30 105.4 30.2 2.8e-30 105.4 30.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM251 PF15190.6 GAM37273.1 - 0.05 13.5 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Transmembrane protein 251 Hydantoinase_B PF02538.14 GAM37274.1 - 7.2e-195 648.3 0.2 9.3e-195 647.9 0.2 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 GAM37274.1 - 1.6e-89 300.1 0.2 3.4e-89 299.0 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GAM37274.1 - 1.2e-57 194.5 0.1 1.2e-54 184.7 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MFS_2 PF13347.6 GAM37275.1 - 1.9e-10 39.9 9.2 1.9e-10 39.9 9.2 2.9 2 1 1 3 3 3 1 MFS/sugar transport protein PUCC PF03209.15 GAM37275.1 - 0.00012 21.2 1.1 0.00025 20.2 1.1 1.5 1 0 0 1 1 1 1 PUCC protein Glyco_transf_8 PF01501.20 GAM37276.1 - 6.8e-12 45.5 0.0 3.2e-11 43.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 DUF5415 PF17436.2 GAM37276.1 - 0.076 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5415) PhyH PF05721.13 GAM37277.1 - 5.9e-05 23.4 0.0 0.0012 19.2 0.0 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 4HBT_3 PF13622.6 GAM37278.1 - 4.6e-40 138.4 0.0 5.4e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 GAM37278.1 - 0.11 12.9 0.0 0.33 11.3 0.0 1.9 1 1 0 1 1 1 0 Thioesterase superfamily Peptidase_S64 PF08192.11 GAM37279.1 - 1.4e-07 30.5 0.0 8.5e-07 27.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase family S64 DUF3431 PF11913.8 GAM37280.1 - 4.6e-77 258.6 0.3 6.1e-77 258.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF4217 PF13959.6 GAM37280.1 - 6.1e-17 61.6 0.1 1.1e-16 60.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) tRNA-synt_1e PF01406.19 GAM37281.1 - 7.7e-108 360.4 0.0 1.2e-107 359.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 GAM37281.1 - 4.9e-05 22.2 0.2 0.049 12.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAM37281.1 - 0.14 10.3 0.0 0.72 8.0 0.0 2.1 3 0 0 3 3 3 0 tRNA synthetases class I (I, L, M and V) IFT20 PF14931.6 GAM37281.1 - 0.35 11.0 0.0 0.35 11.0 0.0 2.7 4 0 0 4 4 4 0 Intraflagellar transport complex B, subunit 20 Fungal_trans PF04082.18 GAM37283.1 - 1.4e-22 80.0 0.4 2e-22 79.5 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cep3 PF16846.5 GAM37283.1 - 0.005 15.4 0.1 0.01 14.3 0.0 1.5 2 0 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit B RTX_C PF08339.10 GAM37283.1 - 0.099 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 RTX C-terminal domain Bac_rhamnosid6H PF17389.2 GAM37284.1 - 1.8e-09 37.4 0.4 3.1e-09 36.5 0.4 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 GAM37284.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain adh_short_C2 PF13561.6 GAM37285.1 - 2.2e-55 187.8 4.3 7.7e-55 186.0 4.3 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM37285.1 - 1.1e-30 106.6 3.6 2.6e-30 105.3 3.6 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM37285.1 - 4.2e-05 23.5 0.5 7e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 KR domain MTS PF05175.14 GAM37285.1 - 0.093 12.3 0.5 0.26 10.8 0.4 1.7 1 1 1 2 2 2 0 Methyltransferase small domain 3HCDH_N PF02737.18 GAM37285.1 - 0.12 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_3 PF00933.21 GAM37286.1 - 2e-57 195.0 0.0 2.4e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DUF1707 PF08044.11 GAM37286.1 - 0.015 15.4 0.1 0.067 13.3 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) CRAL_TRIO PF00650.20 GAM37287.1 - 4.6e-24 84.9 0.0 7.5e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAM37287.1 - 3e-06 27.3 0.0 7.5e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Peptidase_A4 PF01828.17 GAM37288.1 - 2.2e-69 233.1 19.2 3.1e-69 232.6 19.2 1.2 1 0 0 1 1 1 1 Peptidase A4 family DUF1869 PF08956.10 GAM37288.1 - 0.00052 19.9 1.3 0.032 14.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1869) DHFR_2 PF06442.11 GAM37288.1 - 0.059 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 R67 dihydrofolate reductase MFS_1 PF07690.16 GAM37289.1 - 7.7e-21 74.4 9.9 2.4e-20 72.8 9.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 GAM37289.1 - 3.3e-09 35.6 3.2 1.5e-08 33.4 3.2 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 GAM37289.1 - 0.00038 19.1 4.3 0.0056 15.3 0.0 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein Flavi_NS4A PF01350.17 GAM37289.1 - 0.002 18.1 0.6 0.0047 16.9 0.0 2.0 2 0 0 2 2 2 1 Flavivirus non-structural protein NS4A DUF4525 PF15027.6 GAM37289.1 - 0.1 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Aldolase_II PF00596.21 GAM37290.1 - 6.3e-47 159.9 0.1 8.3e-47 159.5 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ADH_zinc_N PF00107.26 GAM37291.1 - 8.5e-10 38.7 1.0 5.8e-08 32.8 1.0 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM37291.1 - 1.4e-07 31.4 0.1 1.1e-06 28.5 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM37291.1 - 2.4e-07 31.8 0.0 6.3e-07 30.5 0.0 1.6 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 GAM37292.1 - 9.8e-10 38.4 14.3 1.8e-09 37.6 14.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM37292.1 - 8.4e-07 28.3 0.0 1.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.25 GAM37293.1 - 0.00014 22.1 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM37293.1 - 0.0002 21.7 0.0 0.00034 21.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM37293.1 - 0.00064 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FAD_binding_2 PF00890.24 GAM37294.1 - 6.5e-38 130.9 2.5 7.3e-37 127.4 2.5 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAM37294.1 - 1.5e-06 27.8 3.3 1.5e-06 27.8 3.3 2.6 3 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM37294.1 - 4.1e-06 25.8 2.1 0.0023 16.7 0.1 3.2 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 GAM37294.1 - 6.8e-06 25.9 4.5 6.8e-06 25.9 4.5 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM37294.1 - 0.00025 20.4 3.0 0.0031 16.8 1.5 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM37294.1 - 0.0016 17.8 0.1 0.024 13.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM37294.1 - 0.0017 17.5 7.6 0.006 15.7 1.6 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAM37294.1 - 0.005 16.1 0.7 0.026 13.8 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 GAM37294.1 - 0.013 14.9 0.2 0.028 13.7 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 GAM37294.1 - 0.03 14.9 0.4 3.4 8.3 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 GAM37294.1 - 0.03 13.7 0.1 0.26 10.6 0.0 2.4 2 1 1 3 3 3 0 GMC oxidoreductase NAD_binding_8 PF13450.6 GAM37294.1 - 0.1 12.8 0.5 0.37 11.1 0.5 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAM37294.1 - 0.13 11.5 0.4 0.47 9.7 0.2 2.0 2 0 0 2 2 2 0 Thi4 family PALP PF00291.25 GAM37294.1 - 0.14 11.5 1.2 0.23 10.8 0.5 1.6 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme DUF3150 PF11348.8 GAM37294.1 - 0.14 11.3 0.2 0.3 10.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) adh_short PF00106.25 GAM37295.1 - 9.3e-23 80.7 0.1 6.4e-17 61.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37295.1 - 4.9e-15 55.7 0.1 3.2e-10 40.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM37295.1 - 6.7e-07 29.4 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM37295.1 - 0.0034 16.6 0.0 0.0057 15.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAM37295.1 - 0.0049 16.4 0.0 0.007 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM37295.1 - 0.095 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HET PF06985.11 GAM37296.1 - 1.4e-12 48.2 1.8 4.9e-11 43.2 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Alanine_zipper PF11839.8 GAM37297.1 - 0.065 13.6 7.4 1.6 9.1 0.4 2.2 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein MFS_1 PF07690.16 GAM37298.1 - 6.5e-36 124.0 66.5 1.6e-35 122.7 61.0 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM37298.1 - 2.3e-21 75.9 25.0 3.2e-21 75.4 25.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM37298.1 - 1.6e-13 50.3 5.7 1.6e-13 50.3 5.7 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 GAM37298.1 - 5.8 5.1 23.6 0.1 10.8 6.9 4.1 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 GAM37299.1 - 4.3e-10 39.1 0.2 7.4e-10 38.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_18 PF00704.28 GAM37300.1 - 4.8e-22 79.1 1.6 1.2e-21 77.8 1.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Fungal_trans PF04082.18 GAM37301.1 - 0.017 14.1 0.3 0.033 13.2 0.3 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short PF00106.25 GAM37302.1 - 4.6e-38 130.6 0.0 6.4e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37302.1 - 5.5e-29 101.4 0.1 2.4e-28 99.3 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM37302.1 - 1.1e-14 54.8 0.0 1.6e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM37302.1 - 6.9e-07 28.7 0.0 8.4e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAM37302.1 - 0.016 14.7 0.1 0.085 12.3 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2964 PF11177.8 GAM37302.1 - 0.055 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) Pyr_redox_2 PF07992.14 GAM37302.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 GAM37302.1 - 0.12 11.7 0.4 2.7 7.3 0.1 2.1 2 0 0 2 2 2 0 ThiF family GDP_Man_Dehyd PF16363.5 GAM37302.1 - 0.16 11.3 0.1 0.62 9.4 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Pro-kuma_activ PF09286.11 GAM37303.1 - 1.2e-38 132.6 0.1 1.6e-37 128.9 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAM37303.1 - 2.9e-05 23.5 0.7 7.8e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Subtilase family ABC_tran PF00005.27 GAM37304.1 - 2.8e-44 151.0 0.1 1.5e-26 93.5 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 GAM37304.1 - 1.3e-16 61.1 24.3 3.4e-08 33.5 15.6 3.1 2 1 1 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.6 GAM37304.1 - 1.2e-10 41.7 3.0 0.07 12.9 0.0 4.2 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM37304.1 - 1.1e-08 34.8 1.4 0.22 10.9 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM37304.1 - 1.3e-05 24.8 0.8 0.069 12.9 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM37304.1 - 2.6e-05 24.2 0.7 0.18 11.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM37304.1 - 5.1e-05 23.3 0.1 0.2 11.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAM37304.1 - 6.2e-05 23.1 1.5 0.055 13.5 0.3 2.4 2 0 0 2 2 2 2 Dynamin family AAA_18 PF13238.6 GAM37304.1 - 0.00019 22.0 0.0 0.055 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 GAM37304.1 - 0.0002 21.9 0.6 0.42 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 GAM37304.1 - 0.0003 20.6 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 GAM37304.1 - 0.00034 20.2 0.4 0.28 10.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_16 PF13191.6 GAM37304.1 - 0.00042 20.8 0.2 1.2 9.5 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAM37304.1 - 0.00079 19.7 3.8 0.8 10.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 GAM37304.1 - 0.0011 19.1 1.3 0.15 12.2 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAM37304.1 - 0.0014 18.4 0.2 0.2 11.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 GAM37304.1 - 0.0027 17.3 0.3 1.8 8.1 0.1 2.7 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 GAM37304.1 - 0.0092 15.1 2.7 0.12 11.4 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 GAM37304.1 - 0.011 15.1 2.0 0.36 10.2 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 GAM37304.1 - 0.013 14.8 0.1 3.1 7.0 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 GAM37304.1 - 0.014 15.6 0.2 9.4 6.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 GAM37304.1 - 0.018 15.0 1.5 1.9 8.4 0.0 3.0 3 0 0 3 3 3 0 NACHT domain Septin PF00735.18 GAM37304.1 - 0.018 14.3 0.1 0.37 10.0 0.0 2.2 2 0 0 2 2 2 0 Septin cobW PF02492.19 GAM37304.1 - 0.042 13.4 2.4 5.9 6.4 0.6 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 GAM37304.1 - 0.045 14.1 0.2 7.3 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Sigma54_activat PF00158.26 GAM37304.1 - 0.061 13.0 0.0 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 GAM37304.1 - 0.075 12.8 0.3 8.5 6.0 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 GAM37304.1 - 0.084 13.3 0.4 5 7.5 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAM37304.1 - 0.1 12.3 0.7 11 5.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 GAM37304.1 - 0.11 12.3 0.1 0.4 10.4 0.1 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_5 PF07728.14 GAM37304.1 - 0.16 12.0 0.7 49 3.9 0.0 3.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.15 GAM37304.1 - 0.28 9.9 1.3 11 4.6 0.1 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATP_bind_1 PF03029.17 GAM37304.1 - 0.3 10.8 2.4 8.3 6.1 0.5 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.9 GAM37304.1 - 0.32 9.8 4.4 0.68 8.8 0.3 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 GAM37304.1 - 0.48 10.5 6.6 0.13 12.3 0.4 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain IstB_IS21 PF01695.17 GAM37304.1 - 1 9.0 3.0 4.3 7.0 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Pox_A32 PF04665.12 GAM37304.1 - 1.7 8.1 3.7 3.2 7.1 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein FAD_binding_3 PF01494.19 GAM37305.1 - 1.7e-28 99.9 0.0 2.6e-27 96.0 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM37305.1 - 4.8e-07 29.3 0.1 0.00092 18.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM37305.1 - 2.6e-06 26.9 0.0 0.021 14.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 GAM37305.1 - 5e-05 22.5 0.0 0.0011 18.1 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.14 GAM37305.1 - 0.0032 16.4 0.1 2.6 6.8 0.2 3.0 2 1 1 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 GAM37305.1 - 0.0035 16.1 0.0 0.027 13.2 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 GAM37305.1 - 0.0099 16.1 0.1 0.02 15.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAM37305.1 - 0.019 14.9 0.2 0.94 9.4 0.1 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 GAM37305.1 - 0.041 13.5 0.6 0.58 9.7 0.6 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAM37305.1 - 0.095 11.7 0.0 1 8.3 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 GAM37305.1 - 0.18 12.4 0.0 33 5.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PepX_C PF08530.10 GAM37306.1 - 1.1e-27 97.5 0.0 2e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 GAM37306.1 - 3.6e-24 85.8 0.0 6.6e-24 84.9 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 GAM37306.1 - 0.079 12.2 0.0 0.18 11.1 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAM37306.1 - 0.098 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Methyltransf_3 PF01596.17 GAM37307.1 - 4.8e-28 97.8 0.0 7.6e-28 97.1 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.6 GAM37307.1 - 8.3e-11 41.9 0.0 1.1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 GAM37307.1 - 1.9e-10 41.7 0.0 3.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAM37307.1 - 7.9e-09 35.6 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 GAM37307.1 - 1e-06 29.4 0.0 3.4e-06 27.7 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM37307.1 - 0.0016 19.0 0.0 0.017 15.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAM37307.1 - 0.0067 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 GAM37307.1 - 0.0074 17.0 0.0 0.018 15.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM37307.1 - 0.056 12.8 0.0 0.086 12.2 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Say1_Mug180 PF10340.9 GAM37308.1 - 0.00024 20.1 0.0 0.00027 19.9 0.0 1.0 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 GAM37308.1 - 0.003 17.5 0.0 0.0035 17.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pyr_redox_2 PF07992.14 GAM37309.1 - 1.3e-39 136.2 0.5 1.7e-39 135.9 0.5 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM37309.1 - 3.8e-13 49.8 0.7 3.4e-10 40.3 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM37309.1 - 2.3e-08 33.5 1.4 0.013 14.6 0.0 3.1 2 1 1 3 3 3 3 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAM37309.1 - 2.9e-08 33.3 1.5 1.4e-06 27.8 0.4 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM37309.1 - 0.00019 21.1 3.3 0.2 11.2 0.1 3.4 2 1 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM37309.1 - 0.00038 20.5 1.2 2.4 8.1 0.1 3.7 3 1 1 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 GAM37309.1 - 0.00046 19.4 1.2 11 5.0 0.0 3.9 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 GAM37309.1 - 0.0011 18.3 0.7 0.092 12.0 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 GAM37309.1 - 0.0061 15.9 0.4 0.016 14.5 0.1 1.7 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 GAM37309.1 - 0.016 13.9 6.6 0.33 9.6 0.2 3.3 3 1 1 4 4 4 0 HI0933-like protein DUF5130 PF17174.4 GAM37309.1 - 0.026 14.7 0.4 0.13 12.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5130) KR PF08659.10 GAM37309.1 - 0.031 14.2 0.1 0.054 13.4 0.1 1.4 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.18 GAM37309.1 - 0.071 13.4 0.1 12 6.1 0.0 2.8 2 0 0 2 2 2 0 TrkA-N domain SH3_10 PF17902.1 GAM37309.1 - 0.082 13.0 0.2 0.35 11.0 0.1 2.1 2 0 0 2 2 2 0 SH3 domain Trp_halogenase PF04820.14 GAM37309.1 - 0.35 9.7 2.2 3.7 6.3 0.0 2.9 4 0 0 4 4 4 0 Tryptophan halogenase Ferric_reduct PF01794.19 GAM37310.1 - 4.5e-22 78.5 9.0 4.5e-22 78.5 9.0 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAM37310.1 - 1.6e-13 50.7 0.0 4.2e-07 30.0 0.0 2.3 1 1 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 GAM37310.1 - 1.3e-05 25.3 0.1 0.003 17.7 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 GAM37310.1 - 0.027 15.1 0.0 0.054 14.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF4153 PF13687.6 GAM37310.1 - 0.11 12.2 12.1 0.15 11.7 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4153) DUF3309 PF11752.8 GAM37310.1 - 1.3 9.1 6.1 0.74 9.9 1.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) Sulfotransfer_4 PF17784.1 GAM37311.1 - 6.5e-58 196.1 0.0 7.8e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAM37311.1 - 2.9e-06 27.8 0.0 1.8e-05 25.2 0.0 2.2 1 1 1 2 2 2 1 Sulfotransferase family Sugar_tr PF00083.24 GAM37312.1 - 2.1e-68 231.3 30.7 2.6e-67 227.6 30.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37312.1 - 5.7e-21 74.8 32.2 5.7e-21 74.8 32.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM37312.1 - 6.6e-07 28.2 9.6 6.6e-07 28.2 9.6 2.6 2 1 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.13 GAM37312.1 - 3.4e-05 22.5 1.8 5.6e-05 21.8 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short_C2 PF13561.6 GAM37313.1 - 8.1e-53 179.4 0.0 1.1e-52 179.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM37313.1 - 2.2e-45 154.6 0.1 2.7e-45 154.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM37313.1 - 4e-11 43.2 0.1 6.1e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAM37313.1 - 0.002 17.6 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 GAM37313.1 - 0.024 13.8 0.1 0.032 13.3 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Phage_ABA_S PF18066.1 GAM37313.1 - 0.052 14.2 0.0 0.12 13.1 0.0 1.6 1 0 0 1 1 1 0 Phage ABA sandwich domain DUF4185 PF13810.6 GAM37314.1 - 0.00021 20.6 3.5 0.00052 19.3 3.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4185) ZZ PF00569.17 GAM37315.1 - 0.051 13.4 0.8 0.051 13.4 0.8 3.3 3 0 0 3 3 3 0 Zinc finger, ZZ type HET PF06985.11 GAM37317.1 - 1.5e-07 31.9 5.1 1.1e-06 29.0 0.0 3.3 2 1 1 3 3 3 1 Heterokaryon incompatibility protein (HET) DUF365 PF04033.12 GAM37317.1 - 0.12 12.6 0.6 0.27 11.5 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Fungal_trans PF04082.18 GAM37318.1 - 1.9e-29 102.6 0.7 3.2e-29 101.8 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 GAM37318.1 - 2.2e-28 99.2 22.3 2.2e-28 99.2 22.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_2 PF04909.14 GAM37319.1 - 8.6e-29 101.2 0.6 1.3e-28 100.7 0.6 1.2 1 0 0 1 1 1 1 Amidohydrolase EAL PF00563.20 GAM37319.1 - 0.13 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 EAL domain MFS_1 PF07690.16 GAM37320.1 - 2.9e-26 92.3 18.0 4.1e-26 91.7 18.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ion_trans_2 PF07885.16 GAM37321.1 - 9.1e-30 102.5 22.3 1e-15 57.5 6.9 2.3 2 0 0 2 2 2 2 Ion channel ArAE_2 PF10334.9 GAM37322.1 - 3.5e-57 193.9 0.1 4.9e-57 193.4 0.1 1.2 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 GAM37322.1 - 6e-30 104.7 8.5 1.5e-29 103.4 5.6 2.4 3 0 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 GAM37322.1 - 6.8e-10 39.2 13.9 6.8e-10 39.2 13.9 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like SIR2_2 PF13289.6 GAM37322.1 - 0.062 13.4 0.1 0.79 9.8 0.0 2.3 2 0 0 2 2 2 0 SIR2-like domain ALMT PF11744.8 GAM37322.1 - 0.098 11.5 7.5 0.22 10.3 7.5 1.5 1 1 0 1 1 1 0 Aluminium activated malate transporter Pro_3_hydrox_C PF05373.11 GAM37322.1 - 0.18 11.9 0.0 0.49 10.5 0.0 1.6 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Ldh_2 PF02615.14 GAM37323.1 - 5.4e-116 387.4 0.2 6.1e-116 387.2 0.2 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Gly_rich_SFCGS PF14272.6 GAM37323.1 - 0.075 13.0 0.3 0.15 12.0 0.3 1.4 1 0 0 1 1 1 0 Glycine-rich SFCGS 2-Hacid_dh_C PF02826.19 GAM37324.1 - 1.8e-48 164.3 0.0 2.8e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAM37324.1 - 6e-22 77.7 0.1 7.5e-22 77.4 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 GAM37324.1 - 0.028 14.5 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain RraA-like PF03737.15 GAM37325.1 - 4.9e-34 117.7 0.0 6.1e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA GFO_IDH_MocA PF01408.22 GAM37326.1 - 2.1e-18 67.3 0.0 4.1e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 GAM37326.1 - 0.0031 17.8 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 GAM37326.1 - 0.015 15.9 0.4 0.11 13.1 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 GAM37326.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FB_lectin PF07367.11 GAM37327.1 - 1.2e-42 145.2 0.1 1.9e-42 144.5 0.1 1.3 1 0 0 1 1 1 1 Fungal fruit body lectin adh_short PF00106.25 GAM37327.1 - 1.7e-26 92.9 0.7 3e-26 92.1 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37327.1 - 2.4e-22 79.7 3.1 1e-21 77.6 1.2 2.4 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM37327.1 - 1.6e-06 28.1 0.1 2.8e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Fusion_gly PF00523.18 GAM37327.1 - 0.08 11.2 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Aldo_ket_red PF00248.21 GAM37328.1 - 2.9e-49 167.9 0.0 3.5e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Chlorosome_CsmC PF11098.8 GAM37329.1 - 0.14 12.2 5.4 0.32 11.0 5.4 1.7 1 1 0 1 1 1 0 Chlorosome envelope protein C LEP503 PF15221.6 GAM37329.1 - 0.34 11.3 1.8 0.37 11.1 0.4 1.8 1 1 1 2 2 2 0 Lens epithelial cell protein LEP503 VPS13_C PF16909.5 GAM37329.1 - 0.35 10.6 3.4 0.24 11.2 1.5 1.7 1 1 1 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal Hydantoinase_B PF02538.14 GAM37330.1 - 7.6e-198 658.1 0.4 1e-197 657.7 0.4 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 GAM37330.1 - 2.2e-105 352.1 0.0 3.9e-105 351.3 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GAM37330.1 - 2.7e-44 151.0 2.5 6.6e-43 146.5 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.9 GAM37330.1 - 0.023 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature MFS_1 PF07690.16 GAM37331.1 - 2e-35 122.4 27.4 2.5e-35 122.0 27.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM37331.1 - 0.00058 19.3 5.6 0.00058 19.3 5.6 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DAO PF01266.24 GAM37332.1 - 7e-45 154.1 0.0 8.3e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM37332.1 - 5e-07 29.8 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM37332.1 - 7.9e-06 25.3 0.0 0.11 11.7 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM37332.1 - 0.0003 20.0 0.1 0.1 11.6 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Shikimate_DH PF01488.20 GAM37332.1 - 0.00035 20.6 0.0 0.00091 19.3 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 GAM37332.1 - 0.00067 19.0 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 GAM37332.1 - 0.0014 18.7 0.1 1 9.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAM37332.1 - 0.01 15.1 0.0 0.047 12.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 GAM37332.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 GAM37332.1 - 0.024 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.18 GAM37332.1 - 0.041 14.1 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Glu_dehyd_C PF16912.5 GAM37332.1 - 0.055 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 GAM37332.1 - 0.078 13.4 0.0 0.14 12.6 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding PglD_N PF17836.1 GAM37332.1 - 0.085 13.5 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 PglD N-terminal domain Thi4 PF01946.17 GAM37332.1 - 0.1 11.8 0.1 0.23 10.6 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 GAM37332.1 - 0.12 13.0 0.0 0.56 10.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM37332.1 - 0.13 11.1 0.1 6.1 5.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.23 GAM37332.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.24 GAM37332.1 - 0.14 11.2 0.2 0.55 9.2 0.2 1.9 1 1 0 1 1 1 0 FAD binding domain GFO_IDH_MocA PF01408.22 GAM37332.1 - 0.17 12.7 0.0 0.37 11.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Fungal_trans_2 PF11951.8 GAM37333.1 - 2.1e-60 204.6 2.4 2.6e-60 204.3 2.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PNP_UDP_1 PF01048.20 GAM37334.1 - 6e-11 42.0 0.0 1.7e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 GAM37334.1 - 1.6e-05 25.4 0.2 0.00021 21.8 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM37334.1 - 0.00092 19.5 1.0 1.3 9.8 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 GAM37334.1 - 0.0093 16.4 2.1 0.099 13.1 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat Tropomyosin PF00261.20 GAM37334.1 - 0.12 11.7 5.0 0.15 11.4 1.2 2.2 2 0 0 2 2 2 0 Tropomyosin Methyltransf_2 PF00891.18 GAM37336.1 - 1.4e-07 31.1 0.0 2.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 GAM37336.1 - 0.00035 20.4 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 GAM37337.1 - 4.6e-20 71.9 22.7 4.6e-20 71.9 22.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAM37337.1 - 4.4e-05 22.0 15.2 0.0025 16.2 0.3 3.2 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Collectrin PF16959.5 GAM37337.1 - 7.6 6.3 9.9 2 8.2 0.3 2.5 2 0 0 2 2 2 0 Renal amino acid transporter Fungal_trans PF04082.18 GAM37338.1 - 8.8e-21 74.1 0.2 3.6e-20 72.1 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM37338.1 - 1.9e-07 31.1 12.7 3.5e-07 30.2 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.15 GAM37339.1 - 1.7e-30 107.0 0.0 2.8e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 GAM37339.1 - 2.9e-17 63.3 0.0 5.8e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.11 GAM37339.1 - 1e-12 48.1 0.0 2.8e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 GAM37339.1 - 1.5e-08 34.8 0.0 3.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 GAM37339.1 - 1.8e-05 24.4 1.4 1.8e-05 24.4 1.4 1.8 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 GAM37339.1 - 0.035 14.7 0.0 0.089 13.4 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FYVE PF01363.21 GAM37339.1 - 9.1 6.5 10.9 28 4.9 10.9 1.8 1 0 0 1 1 1 0 FYVE zinc finger Prenyltransf PF01255.19 GAM37340.1 - 0.19 11.2 0.0 0.58 9.6 0.0 1.9 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase Sec10 PF07393.11 GAM37341.1 - 1.8e-199 664.7 0.0 6.8e-185 616.5 0.0 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec10 LpxC PF03331.13 GAM37341.1 - 0.0075 15.8 0.0 0.028 13.9 0.0 1.9 2 0 0 2 2 2 1 UDP-3-O-acyl N-acetylglycosamine deacetylase GCD14 PF08704.10 GAM37341.1 - 0.09 12.4 0.9 0.12 12.0 0.1 1.6 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Baculo_PEP_C PF04513.12 GAM37341.1 - 0.15 12.1 6.2 2.9 7.9 0.2 3.7 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Erythro-docking PF09277.11 GAM37341.1 - 0.25 11.3 1.1 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 Erythronolide synthase, docking BP28CT PF08146.12 GAM37341.1 - 0.3 10.9 2.2 2.5 7.9 0.0 2.8 2 1 0 2 2 2 0 BP28CT (NUC211) domain ABC2_membrane PF01061.24 GAM37342.1 - 1.5e-56 191.1 41.9 9.1e-36 123.2 22.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 GAM37342.1 - 1.8e-30 106.3 0.0 6.1e-22 78.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAM37342.1 - 8.3e-17 60.9 0.1 8.3e-17 60.9 0.1 2.4 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 GAM37342.1 - 1.6e-10 40.6 11.1 1.6e-10 40.6 11.1 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 GAM37342.1 - 0.00051 20.0 0.2 0.53 10.0 0.0 2.9 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAM37342.1 - 0.00097 19.6 0.1 0.002 18.5 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 GAM37342.1 - 0.0012 18.4 0.0 0.95 8.8 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAM37342.1 - 0.0037 17.2 0.2 0.0068 16.3 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 GAM37342.1 - 0.0074 16.0 0.2 0.019 14.7 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 GAM37342.1 - 0.011 16.3 0.0 0.031 14.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAM37342.1 - 0.018 15.3 0.1 0.055 13.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain PDR_assoc PF08370.11 GAM37342.1 - 0.021 14.5 0.7 0.068 12.9 0.7 1.9 1 0 0 1 1 1 0 Plant PDR ABC transporter associated AAA_23 PF13476.6 GAM37342.1 - 0.024 15.1 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAM37342.1 - 0.031 14.5 0.0 0.082 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAM37342.1 - 0.036 14.4 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAM37342.1 - 0.077 12.6 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAM37342.1 - 0.096 12.4 0.3 0.21 11.3 0.3 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAM37342.1 - 0.12 12.3 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 GAM37342.1 - 0.12 12.0 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 GAM37343.1 - 3.8e-15 55.6 0.4 7e-15 54.8 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain IU_nuc_hydro PF01156.19 GAM37344.1 - 1.8e-59 201.8 0.0 2.1e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PfkB PF00294.24 GAM37345.1 - 6.2e-26 91.4 0.0 8e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Fungal_trans_2 PF11951.8 GAM37346.1 - 2.4e-12 46.4 4.0 5.2e-12 45.3 4.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Transp_cyt_pur PF02133.15 GAM37347.1 - 1e-21 77.3 43.3 4.5e-21 75.1 43.3 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CMD PF02627.20 GAM37348.1 - 8.5e-07 28.9 0.1 7.6e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family MFS_1 PF07690.16 GAM37349.1 - 1.1e-17 64.0 49.5 1.8e-17 63.3 46.4 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM37349.1 - 1.2e-17 63.6 17.9 2.5e-17 62.6 17.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM37349.1 - 4.5e-06 25.8 5.5 4.5e-06 25.8 5.5 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter DUF1772 PF08592.11 GAM37349.1 - 0.0058 16.9 0.1 0.0058 16.9 0.1 5.1 3 2 3 6 6 5 1 Domain of unknown function (DUF1772) COesterase PF00135.28 GAM37350.1 - 9.5e-58 196.3 0.0 1.3e-57 195.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM37350.1 - 9.9e-08 32.1 0.2 7.3e-07 29.3 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM37350.1 - 0.0053 17.4 0.1 0.0089 16.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 GAM37350.1 - 0.016 14.1 0.0 0.1 11.5 0.0 1.8 2 0 0 2 2 2 0 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 GAM37350.1 - 0.064 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family SnoaL_4 PF13577.6 GAM37351.1 - 1.8e-10 41.0 2.7 2.5e-10 40.6 2.7 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 GAM37351.1 - 0.009 16.6 0.7 0.015 15.9 0.6 1.4 1 1 0 1 1 1 1 SnoaL-like domain FAD_binding_3 PF01494.19 GAM37352.1 - 1.8e-49 168.8 0.0 2.3e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM37352.1 - 0.00014 21.2 0.0 0.00023 20.5 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM37352.1 - 0.00023 20.3 0.0 0.0015 17.7 0.0 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 GAM37352.1 - 0.00059 20.3 0.1 0.0033 17.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM37352.1 - 0.00097 19.3 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAM37352.1 - 0.001 17.8 0.0 0.0043 15.8 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 GAM37352.1 - 0.0031 17.2 0.1 0.025 14.2 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 GAM37352.1 - 0.0067 15.6 0.0 0.0094 15.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAM37352.1 - 0.013 14.7 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 GAM37352.1 - 0.031 14.5 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 GAM37352.1 - 0.079 12.2 0.0 0.3 10.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 GAM37352.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 ThiF family FAD_oxidored PF12831.7 GAM37352.1 - 0.15 11.4 0.0 0.33 10.2 0.0 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM37352.1 - 0.18 11.8 0.3 0.36 10.8 0.1 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding TRAP-gamma PF07074.12 GAM37353.1 - 2.3 7.8 5.9 1.3 8.5 0.6 2.4 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Fungal_trans PF04082.18 GAM37354.1 - 4.6e-11 42.3 0.0 8.2e-11 41.4 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Trehalase PF01204.18 GAM37355.1 - 5.3e-160 533.6 0.0 6.2e-160 533.4 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 GAM37355.1 - 8e-12 44.7 0.0 2.3e-11 43.2 0.2 1.7 2 0 0 2 2 2 1 Neutral trehalase Ca2+ binding domain MR_MLE_C PF13378.6 GAM37356.1 - 7.6e-56 189.1 0.0 2.9e-55 187.2 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 GAM37356.1 - 3.9e-05 23.9 0.0 7.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF2517 PF10725.9 GAM37356.1 - 0.06 13.1 0.8 0.13 12.1 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) Glyco_hyd_65N_2 PF14498.6 GAM37357.1 - 1.1e-57 195.6 0.0 1.6e-57 195.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65N PF03636.15 GAM37357.1 - 0.23 11.1 0.0 0.45 10.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Sugar_tr PF00083.24 GAM37358.1 - 2.1e-76 257.6 24.6 2.5e-76 257.4 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37358.1 - 2.4e-15 56.3 42.2 1.7e-11 43.6 35.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM37358.1 - 5.5e-07 28.5 24.7 0.00011 20.9 7.7 2.9 2 1 0 3 3 3 2 MFS/sugar transport protein Pex14_N PF04695.13 GAM37358.1 - 0.00045 20.9 0.8 0.00093 19.9 0.8 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Aldo_ket_red PF00248.21 GAM37359.1 - 1.7e-53 181.7 0.0 2.1e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.13 GAM37360.1 - 6.5e-32 111.0 0.0 8.3e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM37360.1 - 4e-12 46.4 0.0 8.4e-12 45.3 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAM37360.1 - 1e-07 31.3 0.2 1.8e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM37360.1 - 1.2e-06 28.2 0.0 3e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 GAM37360.1 - 2.9e-06 27.7 0.1 5.4e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAM37360.1 - 2.4e-05 24.6 0.1 4.7e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 GAM37360.1 - 5.2e-05 23.2 0.1 8.8e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 GAM37360.1 - 7.4e-05 23.0 0.1 0.00024 21.3 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain adh_short PF00106.25 GAM37360.1 - 0.0012 18.4 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 GAM37360.1 - 0.0034 16.8 0.0 0.005 16.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAM37360.1 - 0.0081 15.3 0.2 0.011 14.8 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 GAM37360.1 - 0.0096 16.0 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 GAM37360.1 - 0.033 13.3 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Glu_dehyd_C PF16912.5 GAM37360.1 - 0.053 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus F420_oxidored PF03807.17 GAM37360.1 - 0.07 13.7 0.0 0.28 11.8 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DXP_reductoisom PF02670.16 GAM37360.1 - 0.16 12.7 0.2 0.27 11.9 0.2 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Aldolase_II PF00596.21 GAM37361.1 - 1.7e-49 168.3 0.1 2.1e-49 168.0 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 2-Hacid_dh_C PF02826.19 GAM37362.1 - 3.6e-39 134.0 0.1 1.2e-35 122.5 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAM37362.1 - 1.3e-23 83.1 0.1 1.9e-23 82.6 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 GAM37362.1 - 0.041 14.4 0.2 0.24 11.9 0.0 2.2 2 1 0 2 2 2 0 XdhC Rossmann domain Peptidase_M20 PF01546.28 GAM37364.1 - 1.3e-20 74.0 0.0 2.2e-20 73.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM37364.1 - 0.0022 17.9 0.1 0.0075 16.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAM37364.1 - 0.019 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Nnf1 PF03980.14 GAM37364.1 - 0.29 11.5 0.6 0.66 10.4 0.2 1.7 2 0 0 2 2 2 0 Nnf1 DJ-1_PfpI PF01965.24 GAM37365.1 - 9.6e-09 35.3 0.0 2.7e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family FAD_binding_3 PF01494.19 GAM37366.1 - 1.3e-13 50.9 0.0 3.2e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 GAM37366.1 - 0.0005 19.2 0.0 0.095 11.7 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_2 PF07992.14 GAM37366.1 - 0.0032 16.7 0.0 0.016 14.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM37366.1 - 0.03 14.5 0.1 0.078 13.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM37366.1 - 0.068 12.7 0.4 7.1 6.1 0.0 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.18 GAM37367.1 - 1e-14 54.3 0.3 1.5e-14 53.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM37367.1 - 2e-07 31.0 9.7 3.9e-07 30.1 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HNH PF01844.23 GAM37367.1 - 0.056 13.6 0.2 0.23 11.6 0.2 2.1 2 0 0 2 2 2 0 HNH endonuclease LigB PF02900.18 GAM37368.1 - 1.9e-31 109.2 0.0 2.4e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Sugar_tr PF00083.24 GAM37369.1 - 9.7e-84 281.8 25.2 1.1e-83 281.6 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37369.1 - 2.4e-25 89.2 41.4 1e-23 83.9 15.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM37369.1 - 6.6e-07 28.1 2.3 1.3e-06 27.1 2.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 GAM37369.1 - 8.8e-06 25.3 3.2 2.1e-05 24.0 3.2 1.6 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF2069 PF09842.9 GAM37369.1 - 1.1 9.5 7.4 0.35 11.1 0.2 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2069) DUF1479 PF07350.12 GAM37370.1 - 1.2e-116 390.0 0.0 1.4e-116 389.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Amidase PF01425.21 GAM37371.1 - 5.8e-100 335.4 0.0 6.5e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 Amidase TLP1_add_C PF18313.1 GAM37371.1 - 0.026 14.5 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain MerR-DNA-bind PF09278.11 GAM37371.1 - 0.097 13.2 0.0 0.61 10.7 0.0 2.1 2 0 0 2 2 2 0 MerR, DNA binding Sortilin-Vps10 PF15902.5 GAM37373.1 - 1.6e-283 940.1 7.6 7.2e-146 486.5 4.3 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 GAM37373.1 - 2.2e-95 317.8 13.3 3.7e-49 167.4 3.0 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 GAM37373.1 - 2.7e-12 44.7 31.5 0.39 10.9 0.2 10.4 10 0 0 10 10 10 6 BNR/Asp-box repeat PSII_BNR PF14870.6 GAM37373.1 - 2.3e-06 27.1 4.3 0.28 10.4 0.0 4.6 4 0 0 4 4 4 3 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.6 GAM37373.1 - 4.5e-06 26.2 0.1 5.3 6.3 0.0 5.8 5 2 0 5 5 5 2 BNR repeat-like domain CHB_HEX_C PF03174.13 GAM37373.1 - 0.0051 16.8 0.4 1.9 8.6 0.0 3.9 4 0 0 4 4 4 1 Chitobiase/beta-hexosaminidase C-terminal domain Mo-co_dimer PF03404.16 GAM37373.1 - 0.033 14.2 0.4 10 6.1 0.0 4.5 4 1 1 5 5 5 0 Mo-co oxidoreductase dimerisation domain DUF4185 PF13810.6 GAM37373.1 - 0.038 13.2 0.9 6.5 5.9 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4185) preSET_CXC PF18264.1 GAM37373.1 - 8.1 7.0 7.2 38 4.9 0.3 2.8 2 0 0 2 2 2 0 CXC domain HET PF06985.11 GAM37375.1 - 5.2e-06 26.9 6.6 0.0012 19.2 1.7 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Sulfotransfer_3 PF13469.6 GAM37375.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family Mito_carr PF00153.27 GAM37376.1 - 4e-63 209.4 1.1 6.1e-21 74.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cgr1 PF03879.14 GAM37377.1 - 1.4e-34 118.7 32.2 1.6e-34 118.5 32.2 1.0 1 0 0 1 1 1 1 Cgr1 family VIR_N PF15912.5 GAM37377.1 - 1.3 8.5 7.1 1.5 8.4 7.1 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal RR_TM4-6 PF06459.12 GAM37377.1 - 6.3 6.5 14.2 6.5 6.5 14.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Snapin_Pallidin PF14712.6 GAM37378.1 - 0.00022 21.6 0.7 0.00042 20.7 0.7 1.5 1 0 0 1 1 1 1 Snapin/Pallidin GAS PF13851.6 GAM37378.1 - 0.00084 18.7 1.3 0.00084 18.7 1.3 1.9 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 GAM37378.1 - 0.035 12.7 18.4 0.05 12.2 18.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF724 PF05266.14 GAM37378.1 - 0.97 9.2 4.5 0.18 11.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) XhlA PF10779.9 GAM37378.1 - 5.9 7.2 5.7 0.62 10.3 0.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA SUI1 PF01253.22 GAM37379.1 - 2.5e-24 85.6 0.5 2.5e-24 85.6 0.5 1.7 2 0 0 2 2 2 1 Translation initiation factor SUI1 DUF1752 PF08550.10 GAM37380.1 - 9.9e-11 41.3 4.6 1.9e-10 40.4 4.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ELMO_CED12 PF04727.13 GAM37381.1 - 7.4e-54 182.5 0.0 1.5e-53 181.6 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 GAM37381.1 - 2.6e-35 121.9 0.2 4.5e-33 114.6 0.0 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain DUF3361 PF11841.8 GAM37381.1 - 1e-14 54.7 0.1 2.5e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Fungal_trans PF04082.18 GAM37383.1 - 3.4e-18 65.6 0.9 5.3e-18 65.0 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Iso_dh PF00180.20 GAM37384.1 - 3.7e-87 292.7 0.0 4.6e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Rad17 PF03215.15 GAM37385.1 - 1.6e-31 109.7 0.0 3e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 GAM37385.1 - 2.7e-06 27.9 0.0 6.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 GAM37385.1 - 3.4e-05 24.3 0.0 0.00017 22.1 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM37385.1 - 0.00085 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GAM37385.1 - 0.01 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 GAM37385.1 - 0.012 14.8 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 GAM37385.1 - 0.014 15.9 0.1 0.11 13.0 0.0 2.4 2 0 0 2 2 2 0 ABC transporter TsaE PF02367.17 GAM37385.1 - 0.028 14.4 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 GAM37385.1 - 0.032 13.4 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 GAM37385.1 - 0.044 13.5 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAM37385.1 - 0.045 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 GAM37385.1 - 0.062 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAM37385.1 - 0.066 13.8 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAM37385.1 - 0.091 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ndc1_Nup PF09531.10 GAM37385.1 - 1.7 7.3 9.8 2.5 6.7 9.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dicty_REP PF05086.12 GAM37385.1 - 2 6.3 11.0 2.8 5.8 11.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.8 GAM37385.1 - 3.1 6.9 12.4 5.2 6.2 12.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pneumo_att_G PF05539.11 GAM37385.1 - 5.1 6.6 17.5 12 5.3 17.5 1.5 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G UAA PF08449.11 GAM37386.1 - 1.2e-84 284.1 13.7 7.6e-60 202.6 1.6 2.1 1 1 0 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.15 GAM37386.1 - 1.9e-05 24.0 0.4 1.9e-05 24.0 0.4 1.8 2 0 0 2 2 2 1 Nucleotide-sugar transporter Oxidored_q2 PF00420.24 GAM37386.1 - 0.8 9.4 7.1 0.39 10.4 0.2 2.7 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Dynamin_M PF01031.20 GAM37387.1 - 1.7e-109 365.5 0.0 3.5e-109 364.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 GAM37387.1 - 1.7e-56 190.9 1.4 3.2e-56 190.0 0.0 2.2 3 0 0 3 3 3 1 Dynamin family GED PF02212.18 GAM37387.1 - 1.7e-31 108.2 0.7 1.7e-31 108.2 0.7 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GAM37387.1 - 0.00014 21.9 0.3 0.00095 19.2 0.3 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 GAM37387.1 - 0.19 12.0 0.0 1 9.6 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SH3_9 PF14604.6 GAM37389.1 - 1.3e-28 98.6 6.8 3.3e-14 52.4 0.6 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 GAM37389.1 - 1.4e-26 91.8 6.2 4.8e-14 51.7 0.6 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 GAM37389.1 - 8.7e-18 63.8 0.1 3.6e-09 36.2 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 GAM37389.1 - 4.8e-16 58.6 0.0 1.1e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AAT PF03417.16 GAM37390.1 - 1.1e-34 120.1 0.0 1.3e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase F-box-like PF12937.7 GAM37391.1 - 0.0046 16.8 0.2 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAM37391.1 - 0.0063 16.4 0.0 0.022 14.7 0.0 1.9 1 0 0 1 1 1 1 F-box domain A_deaminase PF00962.22 GAM37392.1 - 2.5e-123 411.6 0.0 3.7e-123 411.0 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase DJ-1_PfpI PF01965.24 GAM37394.1 - 1.7e-11 44.2 0.0 2.3e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family YbbR PF07949.12 GAM37395.1 - 0.16 12.4 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 YbbR-like protein MFS_1 PF07690.16 GAM37396.1 - 5.9e-30 104.4 38.3 5.9e-30 104.4 38.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily EHN PF06441.12 GAM37397.1 - 1.3e-26 93.1 0.1 2.1e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 GAM37397.1 - 1.3e-10 41.4 0.4 2.6e-10 40.4 0.4 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM37397.1 - 0.36 11.4 8.6 0.32 11.5 5.6 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.16 GAM37398.1 - 5.9e-35 120.8 79.9 1.1e-25 90.4 43.2 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM37399.1 - 5.9e-85 285.8 22.7 6.7e-85 285.6 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37399.1 - 2.3e-43 148.5 45.6 6e-33 114.2 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EMP70 PF02990.16 GAM37399.1 - 0.005 15.6 2.2 0.005 15.6 2.2 3.6 3 1 1 4 4 4 1 Endomembrane protein 70 MFS_1_like PF12832.7 GAM37399.1 - 0.0054 15.6 13.9 0.066 12.1 1.1 2.9 2 1 0 2 2 2 2 MFS_1 like family DUF2463 PF09591.10 GAM37399.1 - 0.025 14.5 3.1 2.5 7.9 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) Glyco_hydro_88 PF07470.13 GAM37400.1 - 3.5e-08 32.9 0.3 8.7e-08 31.6 0.2 1.7 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Bombinin PF05298.11 GAM37401.1 - 0.06 13.0 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Bombinin DUF2264 PF10022.9 GAM37402.1 - 1e-75 255.1 0.4 1.3e-75 254.7 0.4 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Fungal_trans PF04082.18 GAM37403.1 - 5.6e-14 51.8 0.3 1.7e-13 50.2 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM37403.1 - 5.3e-08 32.9 13.5 8.9e-08 32.1 13.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 GAM37407.1 - 1.4e-42 146.1 0.0 1.9e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM37407.1 - 1.4e-36 126.2 0.0 2.4e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAM37407.1 - 4.4e-06 26.0 1.0 0.007 15.5 2.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 GAM37407.1 - 0.00072 18.9 0.1 0.056 12.7 0.1 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM37407.1 - 0.0008 19.1 0.9 0.0018 17.9 0.9 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM37407.1 - 0.00091 18.5 0.6 0.0016 17.7 0.6 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM37407.1 - 0.0047 17.1 0.1 0.014 15.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAM37407.1 - 0.014 14.4 0.3 0.022 13.8 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 GAM37407.1 - 0.052 12.2 1.5 0.087 11.5 1.5 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 GAM37407.1 - 0.062 12.5 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 GAM37407.1 - 0.12 11.2 0.3 0.17 10.7 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 GAM37407.1 - 0.22 10.8 3.0 0.4 10.0 3.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF5355 PF17306.2 GAM37407.1 - 0.23 10.5 0.1 0.34 9.9 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5355) Pyr_redox PF00070.27 GAM37407.1 - 0.28 11.8 1.4 0.66 10.6 1.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2_5_RNA_ligase2 PF13563.6 GAM37408.1 - 3e-33 114.9 0.1 1.4e-32 112.7 0.4 2.0 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily PAP_central PF04928.17 GAM37408.1 - 3.4e-27 95.0 0.0 6.8e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain MJ1316 PF04457.12 GAM37408.1 - 1.2e-20 74.0 0.8 3.5e-20 72.5 0.8 1.9 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Exo_endo_phos PF03372.23 GAM37408.1 - 8.4e-06 25.5 0.0 3.5e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LigT_PEase PF02834.16 GAM37408.1 - 1.9e-05 24.8 0.2 0.051 13.8 0.1 2.9 2 0 0 2 2 2 2 LigT like Phosphoesterase Nrap_D2 PF17403.2 GAM37408.1 - 9.2e-05 22.3 0.0 0.00038 20.2 0.0 2.1 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain NTP_transf_2 PF01909.23 GAM37408.1 - 0.00066 19.9 0.9 0.0019 18.4 0.0 2.2 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 GAM37408.1 - 0.0014 18.8 0.2 0.0042 17.3 0.2 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase Exo_endo_phos_2 PF14529.6 GAM37408.1 - 0.12 12.2 0.7 3.2 7.6 0.0 2.9 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Pyr_redox_2 PF07992.14 GAM37409.1 - 3.4e-07 29.8 0.0 4.4e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAM37409.1 - 7.9e-05 22.1 0.0 0.0029 16.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 GAM37409.1 - 0.00028 21.4 0.0 0.00057 20.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM37409.1 - 0.00032 20.4 0.1 0.00047 19.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM37409.1 - 0.0005 20.2 0.1 0.0018 18.5 0.0 2.1 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 GAM37409.1 - 0.03 14.6 0.0 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 GAM37409.1 - 0.046 13.4 0.1 0.078 12.6 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 GAM37409.1 - 0.16 12.5 0.0 0.21 12.1 0.0 1.4 1 1 0 1 1 1 0 XdhC Rossmann domain Fungal_trans PF04082.18 GAM37410.1 - 3.7e-13 49.1 0.8 5.4e-13 48.6 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HK97-gp10_like PF04883.12 GAM37410.1 - 0.11 13.4 0.0 2.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component PLA2_B PF01735.18 GAM37411.1 - 7e-23 80.8 0.0 1.8e-22 79.5 0.0 1.6 1 1 0 1 1 1 1 Lysophospholipase catalytic domain VWA_2 PF13519.6 GAM37413.1 - 0.0004 21.0 0.0 0.00093 19.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4404 PF14357.6 GAM37414.1 - 0.019 15.6 0.0 0.033 14.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Promethin PF16015.5 GAM37414.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Promethin TPR_1 PF00515.28 GAM37415.1 - 3.6e-06 26.6 1.1 2.5e-05 23.9 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAM37415.1 - 0.00071 19.2 1.4 0.0012 18.5 0.2 2.1 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 GAM37415.1 - 0.014 15.4 1.7 0.08 13.1 0.1 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 GAM37415.1 - 0.042 13.8 1.6 1.3 9.0 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM37415.1 - 0.046 13.9 0.1 0.15 12.4 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat NmrA PF05368.13 GAM37417.1 - 6.2e-21 75.0 0.1 9.7e-21 74.4 0.1 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM37417.1 - 1.8e-05 24.7 0.0 2.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAM37417.1 - 0.0041 16.2 0.0 0.0068 15.5 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM37417.1 - 0.062 12.8 0.0 0.22 10.9 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family bZIP_1 PF00170.21 GAM37419.1 - 7.1e-06 26.0 5.5 1.1e-05 25.5 5.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor ATG16 PF08614.11 GAM37419.1 - 0.004 17.4 2.0 0.0048 17.1 2.0 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Cep57_CLD PF14073.6 GAM37419.1 - 0.011 15.8 2.5 0.015 15.4 2.5 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 TMCO5 PF14992.6 GAM37419.1 - 0.013 15.1 1.0 0.014 15.0 1.0 1.1 1 0 0 1 1 1 0 TMCO5 family DUF5082 PF16888.5 GAM37419.1 - 0.018 15.3 0.2 0.12 12.6 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) bZIP_2 PF07716.15 GAM37419.1 - 0.033 14.3 8.6 0.057 13.5 8.6 1.4 1 0 0 1 1 1 0 Basic region leucine zipper GvpL_GvpF PF06386.11 GAM37419.1 - 0.068 13.1 1.1 0.086 12.8 1.1 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Fib_alpha PF08702.10 GAM37419.1 - 0.26 11.5 1.9 0.5 10.5 1.8 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 GAM37419.1 - 0.29 9.0 0.8 0.33 8.8 0.8 1.0 1 0 0 1 1 1 0 Prominin ABC_tran_Xtn PF12848.7 GAM37419.1 - 0.32 11.0 6.0 0.59 10.2 6.0 1.5 1 1 0 1 1 1 0 ABC transporter DUF1815 PF08844.10 GAM37420.1 - 0.21 11.6 0.1 0.65 10.0 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1815) adh_short PF00106.25 GAM37421.1 - 2.1e-21 76.3 0.0 4.3e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37421.1 - 1.5e-11 44.3 0.0 2.2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM37421.1 - 8.7e-08 32.3 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM37421.1 - 0.00072 19.1 0.0 0.00087 18.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM37421.1 - 0.0035 16.5 0.0 0.0054 15.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein CVNH PF08881.10 GAM37423.1 - 0.00062 20.4 0.2 0.0008 20.1 0.2 1.5 1 1 0 1 1 1 1 CVNH domain TPR_2 PF07719.17 GAM37424.1 - 6.7e-12 44.6 7.7 0.01 15.9 0.0 6.1 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAM37424.1 - 8.4e-12 44.6 7.2 0.00016 21.3 0.1 5.0 5 0 0 5 5 5 3 TPR repeat TPR_1 PF00515.28 GAM37424.1 - 3.3e-11 42.5 3.8 0.1 12.5 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM37424.1 - 4.2e-08 33.4 4.2 0.003 17.8 0.3 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM37424.1 - 4.1e-07 29.7 1.4 5.1 7.6 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM37424.1 - 2.8e-06 27.0 0.1 0.83 9.8 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM37424.1 - 5.2e-06 26.9 8.4 0.0045 17.5 0.0 4.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM37424.1 - 1.4e-05 25.6 12.9 0.0072 17.0 0.0 5.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAM37424.1 - 0.001 19.5 3.0 0.16 12.6 0.1 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM37424.1 - 0.0071 15.8 0.5 0.016 14.6 0.5 1.6 1 0 0 1 1 1 1 MalT-like TPR region HrpB1_HrpK PF09613.10 GAM37424.1 - 0.057 13.1 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_14 PF13428.6 GAM37424.1 - 0.08 13.8 15.5 0.77 10.7 0.0 6.1 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAM37424.1 - 0.11 12.9 4.8 22 5.7 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF4112 PF13430.6 GAM37424.1 - 0.23 11.8 1.5 3.6 7.9 0.2 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4112) TPR_10 PF13374.6 GAM37424.1 - 1.9 8.5 5.6 31 4.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1746 PF08508.10 GAM37425.1 - 0.013 15.8 0.2 2.9 8.3 0.1 2.7 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1746) Acyl-CoA_dh_1 PF00441.24 GAM37427.1 - 9.1e-40 136.3 1.5 1e-39 136.1 1.5 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 GAM37427.1 - 8.6e-15 55.2 0.2 1.2e-14 54.8 0.2 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glyoxalase PF00903.25 GAM37428.1 - 1.2e-06 28.7 0.0 1.5e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TauD PF02668.16 GAM37429.1 - 1.6e-60 205.2 0.5 1.9e-60 205.0 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FMO-like PF00743.19 GAM37430.1 - 1.1e-27 96.7 0.0 1e-17 63.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAM37430.1 - 4.3e-13 49.2 0.0 5.9e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM37430.1 - 1.1e-06 28.0 0.0 0.00014 21.1 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 GAM37430.1 - 1.6e-06 27.6 0.0 3.3e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 GAM37431.1 - 8.2e-37 126.9 18.1 6.8e-34 117.3 9.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 GAM37431.1 - 6.9e-07 28.9 2.6 7.5e-07 28.8 0.7 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 GAM37431.1 - 0.00088 17.9 1.3 0.00088 17.9 1.3 2.2 3 0 0 3 3 3 1 MFS/sugar transport protein CHD5 PF04420.14 GAM37431.1 - 0.9 9.4 3.4 1.7 8.5 0.3 2.9 2 1 1 3 3 3 0 CHD5-like protein Glyco_hydro_7 PF00840.20 GAM37432.1 - 1e-141 472.6 10.9 1e-141 472.6 10.9 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 GAM37432.1 - 3.8e-12 45.9 11.2 3.8e-12 45.9 11.2 4.8 4 0 0 4 4 4 1 Fungal cellulose binding domain DUF3140 PF11338.8 GAM37433.1 - 1.1e-34 118.8 1.1 1.2e-34 118.6 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) DUF1843 PF08898.10 GAM37433.1 - 0.061 13.8 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Gln-synt_C PF00120.24 GAM37434.1 - 1.8e-66 224.5 0.0 2.2e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF3431 PF11913.8 GAM37435.1 - 2.4e-71 239.9 0.1 2.9e-71 239.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) LigB PF02900.18 GAM37436.1 - 1.8e-32 112.5 0.0 2.1e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short PF00106.25 GAM37437.1 - 2.2e-22 79.5 1.3 2.9e-22 79.1 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37437.1 - 1.2e-16 60.9 0.8 1.7e-16 60.5 0.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM37437.1 - 6.5e-08 32.7 2.0 1.2e-07 31.9 1.9 1.4 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 GAM37437.1 - 0.00011 22.7 1.3 0.00048 20.6 0.7 2.2 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 GAM37437.1 - 0.00015 22.0 0.5 0.00028 21.1 0.5 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAM37437.1 - 0.0081 16.2 0.3 0.022 14.8 0.3 1.8 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 GAM37437.1 - 0.15 11.5 0.3 0.24 10.8 0.3 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2OG-FeII_Oxy PF03171.20 GAM37438.1 - 2.1e-17 63.4 0.0 1.2e-16 61.0 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 GAM37438.1 - 7.8e-17 62.1 0.0 1.6e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DNA_pol3_theta PF06440.11 GAM37438.1 - 0.1 12.3 0.2 0.23 11.1 0.2 1.5 1 0 0 1 1 1 0 DNA polymerase III, theta subunit FRD2 PF03197.13 GAM37438.1 - 0.19 12.1 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage FRD2 protein MFS_1 PF07690.16 GAM37439.1 - 2.5e-23 82.6 20.5 2.5e-23 82.6 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily VIT1 PF01988.19 GAM37439.1 - 0.37 10.6 2.0 0.43 10.4 0.3 1.9 2 0 0 2 2 2 0 VIT family DUF5435 PF17503.2 GAM37440.1 - 0.034 13.9 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5435) Aminotran_5 PF00266.19 GAM37441.1 - 2.9e-16 59.4 0.0 1.9e-08 33.7 0.0 2.7 2 1 0 2 2 2 2 Aminotransferase class-V Glyco_hydro_16 PF00722.21 GAM37442.1 - 0.0011 18.5 0.0 0.0045 16.5 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Sensor PF13796.6 GAM37443.1 - 0.028 14.5 0.1 0.028 14.5 0.1 1.4 2 0 0 2 2 2 0 Putative sensor SKG6 PF08693.10 GAM37443.1 - 0.13 11.7 10.2 0.36 10.3 10.2 1.8 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Rax2 PF12768.7 GAM37443.1 - 0.16 11.4 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF5417 PF17438.2 GAM37443.1 - 0.2 12.0 0.6 0.66 10.3 0.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5417) GPI-anchored PF10342.9 GAM37444.1 - 0.0013 19.5 0.8 0.0013 19.5 0.8 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FAD_binding_3 PF01494.19 GAM37445.1 - 1.8e-14 53.8 0.0 8e-14 51.6 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Ribosomal_L3 PF00297.22 GAM37447.1 - 8.1e-181 600.9 12.1 9.2e-181 600.7 12.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 NmrA PF05368.13 GAM37448.1 - 7.6e-59 199.1 0.3 9.5e-59 198.8 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM37448.1 - 1.6e-18 67.2 0.0 2.4e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAM37448.1 - 1.1e-06 27.9 0.0 1.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM37448.1 - 6.7e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAM37448.1 - 0.0041 17.4 0.0 0.0089 16.3 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Acetyltransf_10 PF13673.7 GAM37449.1 - 3.7e-11 43.1 0.0 1.4e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM37449.1 - 6.2e-11 42.6 0.0 2e-09 37.7 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM37449.1 - 3.9e-09 36.8 0.1 8.9e-08 32.4 0.0 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM37449.1 - 0.0026 17.8 0.3 0.013 15.6 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM37449.1 - 0.0033 17.5 0.0 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 GAM37449.1 - 0.0095 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein NuiA PF07924.11 GAM37449.1 - 0.021 15.2 0.3 0.17 12.3 0.3 2.3 1 1 0 1 1 1 0 Nuclease A inhibitor-like protein Arginosuc_synth PF00764.19 GAM37450.1 - 2.1e-149 498.1 0.0 2.4e-149 497.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase tRNA_Me_trans PF03054.16 GAM37450.1 - 0.0036 16.2 0.0 0.0053 15.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 GAM37450.1 - 0.0083 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Methyltransf_25 PF13649.6 GAM37451.1 - 1.1e-14 54.9 0.0 3.3e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM37451.1 - 1.6e-12 47.5 0.0 2.2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM37451.1 - 8.3e-11 42.5 0.0 2.2e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM37451.1 - 2.8e-10 40.3 0.0 3.4e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM37451.1 - 8.5e-10 39.2 0.0 1.9e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM37451.1 - 0.00014 21.5 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 GAM37451.1 - 0.0014 18.8 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 GAM37451.1 - 0.0023 17.3 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain TehB PF03848.14 GAM37451.1 - 0.0029 17.0 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 GAM37451.1 - 0.013 15.5 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 GAM37451.1 - 0.034 13.6 0.0 0.27 10.7 0.0 2.0 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 GAM37451.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Sugar_tr PF00083.24 GAM37452.1 - 3.9e-104 349.0 23.6 4.6e-104 348.8 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37452.1 - 1.4e-26 93.3 33.2 5.1e-19 68.4 8.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 GAM37452.1 - 0.009 14.5 0.3 0.02 13.3 0.3 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector NmrA PF05368.13 GAM37453.1 - 2.8e-35 122.0 0.0 3.8e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM37453.1 - 3.6e-19 69.4 0.0 6e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM37453.1 - 3.9e-05 23.2 0.0 0.00019 21.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM37453.1 - 0.033 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 GAM37453.1 - 0.084 13.1 0.0 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain SBP_bac_6 PF13343.6 GAM37456.1 - 3.4e-19 69.2 0.6 5.1e-19 68.7 0.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 GAM37456.1 - 8e-13 48.8 1.5 1.3e-12 48.2 1.5 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 GAM37456.1 - 9.6e-09 35.6 4.0 4.3e-08 33.5 4.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 GAM37456.1 - 7.5e-06 25.8 0.2 1.2e-05 25.2 0.2 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein ANF_receptor PF01094.28 GAM37456.1 - 0.13 11.4 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Alfin PF12165.8 GAM37457.1 - 0.016 14.9 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Alfin DUF1989 PF09347.10 GAM37458.1 - 3e-51 173.4 0.0 1.2e-50 171.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.21 GAM37458.1 - 8.4e-17 61.2 0.0 1.5e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 GAM37458.1 - 2.8e-07 30.4 0.0 4.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 GAM37458.1 - 0.12 10.7 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Peptidase_C12 PF01088.21 GAM37459.1 - 3.4e-39 134.8 0.0 4.5e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 FAD_binding_3 PF01494.19 GAM37460.1 - 3.3e-61 207.5 0.0 4e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM37460.1 - 1.1e-08 35.1 0.1 1e-07 31.9 0.0 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase Phe_hydrox_dim PF07976.12 GAM37460.1 - 5.5e-07 29.8 0.0 1.4e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 GAM37460.1 - 6e-06 25.6 0.0 1.8e-05 24.0 0.0 1.8 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 GAM37460.1 - 4.2e-05 22.9 0.0 7.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 GAM37460.1 - 0.00013 20.8 0.0 0.00021 20.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 GAM37460.1 - 0.00021 21.5 0.1 0.00073 19.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GAM37460.1 - 0.00021 20.8 0.1 0.00031 20.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM37460.1 - 0.00022 20.5 0.0 0.0021 17.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM37460.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM37460.1 - 0.0013 17.8 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 GAM37460.1 - 0.0024 16.8 0.0 0.0046 15.9 0.0 1.4 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 GAM37460.1 - 0.0088 16.6 0.0 0.02 15.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM37460.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 GAM37460.1 - 0.084 12.3 0.0 3.2 7.2 0.0 2.6 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 GAM37460.1 - 0.087 13.3 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 GAM37460.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Aldedh PF00171.22 GAM37461.1 - 4.9e-41 140.7 0.2 9e-34 116.8 0.0 2.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Oxidored_q6 PF01058.22 GAM37461.1 - 1.1e-22 80.2 0.1 2.2e-22 79.3 0.1 1.5 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Zn_clus PF00172.18 GAM37461.1 - 0.0019 18.3 9.9 0.0034 17.5 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 GAM37462.1 - 7e-59 199.8 0.0 1.4e-58 198.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 SLAC1 PF03595.17 GAM37462.1 - 0.11 11.7 1.2 0.17 11.1 1.2 1.2 1 0 0 1 1 1 0 Voltage-dependent anion channel DUF3176 PF11374.8 GAM37463.1 - 3.1e-33 114.2 4.1 6.8e-33 113.1 4.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) HKR_ArcB_TM PF18415.1 GAM37463.1 - 0.96 10.3 4.3 3.4 8.5 0.2 2.7 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain CshA_NR2 PF18651.1 GAM37464.1 - 0.14 11.4 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Surface adhesin CshA non-repetitive domain 2 HEAT_PBS PF03130.16 GAM37464.1 - 0.14 12.9 1.0 2.8 8.9 0.4 2.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat ETF PF01012.21 GAM37465.1 - 7e-44 149.9 2.6 1.3e-43 149.0 2.6 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 GAM37465.1 - 1.3e-33 114.9 1.4 1.7e-33 114.5 0.3 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Ribosomal_L1 PF00687.21 GAM37466.1 - 2.6e-63 213.5 5.0 4.5e-63 212.7 5.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SUN PF03856.13 GAM37467.1 - 7.2e-85 284.4 11.3 1.1e-84 283.7 11.3 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) MGC-24 PF05283.11 GAM37467.1 - 2.8 8.4 17.2 10 6.6 17.2 2.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Hamartin PF04388.12 GAM37467.1 - 5.4 5.6 11.8 7.2 5.1 11.8 1.1 1 0 0 1 1 1 0 Hamartin protein MIF4G PF02854.19 GAM37468.1 - 3.4e-59 200.0 0.2 6.8e-35 120.6 0.1 3.4 3 0 0 3 3 3 2 MIF4G domain Upf2 PF04050.14 GAM37468.1 - 2.9e-39 134.9 11.8 2.9e-39 134.9 11.8 3.8 5 0 0 5 5 5 1 Up-frameshift suppressor 2 CHCH PF06747.13 GAM37469.1 - 2e-06 27.8 4.9 3.5e-06 27.0 4.9 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 GAM37469.1 - 0.041 14.3 2.3 0.09 13.2 2.3 1.6 1 0 0 1 1 1 0 GCK domain Cytotoxic PF09000.10 GAM37469.1 - 0.05 13.9 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 Cytotoxic UNC45-central PF11701.8 GAM37469.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central DUF4718 PF15842.5 GAM37469.1 - 0.17 11.6 0.6 0.25 11.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) SMBP PF16785.5 GAM37469.1 - 1 9.6 6.0 2.7 8.2 6.0 1.6 1 0 0 1 1 1 0 Small metal-binding protein Septin PF00735.18 GAM37470.1 - 2.6e-121 404.2 0.1 2.6e-121 404.2 0.1 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 GAM37470.1 - 6.1e-09 36.0 0.0 1.8e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM37470.1 - 5.4e-05 23.2 3.4 0.0021 18.0 1.0 3.4 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 GAM37470.1 - 0.0001 21.9 1.2 0.0087 15.6 0.0 3.0 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 GAM37470.1 - 0.00096 19.4 0.0 0.0048 17.1 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 GAM37470.1 - 0.0012 19.4 3.3 0.017 15.7 0.0 2.8 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 GAM37470.1 - 0.004 17.5 0.2 0.013 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 GAM37470.1 - 0.0049 16.2 2.5 0.0074 15.6 0.0 2.2 2 0 0 2 2 2 1 AIG1 family AAA_22 PF13401.6 GAM37470.1 - 0.0058 16.9 0.6 0.024 14.9 0.0 2.4 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAM37470.1 - 0.0099 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Ras PF00071.22 GAM37470.1 - 0.034 13.7 0.0 0.12 12.0 0.0 1.9 1 0 0 1 1 1 0 Ras family Exonuc_VII_L PF02601.15 GAM37470.1 - 0.038 13.6 4.7 0.068 12.7 4.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_24 PF13479.6 GAM37470.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM37470.1 - 0.076 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IIGP PF05049.13 GAM37470.1 - 0.093 11.8 0.2 0.093 11.8 0.2 2.1 2 1 1 3 3 3 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 GAM37470.1 - 0.1 12.7 7.3 0.54 10.3 0.0 3.4 3 1 0 3 3 2 0 Dynamin family RNA_helicase PF00910.22 GAM37470.1 - 0.18 12.2 0.5 1 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 GAM37470.1 - 0.56 10.0 4.1 3.9 7.2 0.0 3.1 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Strep_SA_rep PF06696.11 GAM37470.1 - 8.8 6.5 6.7 0.51 10.4 0.9 1.9 2 0 0 2 2 2 0 Streptococcal surface antigen repeat UPF0121 PF03661.13 GAM37471.1 - 5.8e-33 114.3 3.9 7.8e-33 113.9 3.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Mito_carr PF00153.27 GAM37472.1 - 1.6e-60 201.0 4.2 9.3e-19 67.1 2.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein ANAPC1 PF12859.7 GAM37472.1 - 1.7 9.2 14.6 0.081 13.5 5.8 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Mito_carr PF00153.27 GAM37474.1 - 6e-44 147.9 0.8 5.9e-14 51.8 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein TPK_catalytic PF04263.16 GAM37474.1 - 6e-26 90.9 0.0 1.7e-25 89.4 0.0 1.8 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 GAM37474.1 - 1.6e-15 56.6 0.0 3.1e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Phageshock_PspD PF09584.10 GAM37474.1 - 0.088 12.8 0.4 0.21 11.7 0.4 1.5 1 0 0 1 1 1 0 Phage shock protein PspD (Phageshock_PspD) MRC1 PF09444.10 GAM37474.1 - 0.23 12.0 5.0 0.19 12.2 0.4 2.3 2 0 0 2 2 2 0 MRC1-like domain DUF5114 PF17141.4 GAM37475.1 - 6.5 7.4 8.2 2.2 8.9 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5114) CBM_21 PF03370.13 GAM37476.1 - 1e-36 125.5 0.8 1.8e-36 124.7 0.8 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 GAM37476.1 - 1.6e-09 38.2 1.3 3.1e-09 37.3 1.3 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DNA_circ_N PF07157.12 GAM37476.1 - 0.16 12.3 0.1 4.2 7.8 0.0 2.4 2 0 0 2 2 2 0 DNA circularisation protein N-terminus RNA_polI_A34 PF08208.11 GAM37476.1 - 0.91 9.6 7.6 4.5 7.3 4.3 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 CP12 PF02672.15 GAM37476.1 - 2.4 9.0 4.7 18 6.2 0.0 3.5 4 0 0 4 4 4 0 CP12 domain CENP-T_C PF15511.6 GAM37477.1 - 4.4e-09 36.4 0.1 5.3e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 GAM37477.1 - 1.9e-05 25.1 0.2 2.2e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 GAM37477.1 - 5e-05 23.4 0.2 7.3e-05 22.9 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 GAM37477.1 - 0.00012 22.3 0.1 0.00021 21.5 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 GAM37477.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 GAM37477.1 - 0.0038 17.3 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAM37477.1 - 0.0045 17.0 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 GAM37477.1 - 0.05 13.4 0.2 0.061 13.1 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 GAM37477.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 GAM37477.1 - 0.073 13.1 0.0 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region RAP1 PF07218.11 GAM37478.1 - 1.4 7.1 5.6 1.4 7.1 5.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CorA PF01544.18 GAM37479.1 - 0.00048 19.6 6.9 0.0034 16.7 6.9 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PGAP1 PF07819.13 GAM37480.1 - 6.4e-87 291.1 0.0 1e-86 290.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein adh_short PF00106.25 GAM37480.1 - 2.8e-20 72.6 0.0 4.3e-16 58.9 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37480.1 - 3.3e-08 33.4 0.0 8.6e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Abhydrolase_6 PF12697.7 GAM37480.1 - 2.6e-06 28.2 1.9 5.1e-06 27.3 0.3 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family KR PF08659.10 GAM37480.1 - 0.00022 21.2 0.1 0.00046 20.1 0.1 1.5 1 0 0 1 1 1 1 KR domain Palm_thioest PF02089.15 GAM37480.1 - 0.00023 21.1 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase LCAT PF02450.15 GAM37480.1 - 0.0021 17.3 0.0 0.0038 16.4 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 GAM37480.1 - 0.0022 17.7 0.1 0.0094 15.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM37480.1 - 0.0089 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 GAM37480.1 - 0.023 14.2 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.20 GAM37480.1 - 0.056 13.1 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 GAM37480.1 - 0.062 13.2 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 GAM37480.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family ABC_tran PF00005.27 GAM37481.1 - 8.2e-48 162.4 0.4 3.9e-24 85.7 0.0 4.0 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 GAM37481.1 - 6.8e-30 103.0 0.7 2.6e-29 101.1 0.7 2.1 1 0 0 1 1 1 1 Four helical bundle domain SMC_N PF02463.19 GAM37481.1 - 1.2e-16 60.9 0.0 4.3e-06 26.3 0.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAM37481.1 - 2.4e-15 57.2 0.2 0.0022 17.9 0.0 4.6 5 0 0 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAM37481.1 - 5e-10 40.2 1.5 0.0002 22.0 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 GAM37481.1 - 5.8e-09 35.6 0.1 0.0041 16.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM37481.1 - 1.5e-07 31.4 0.0 0.0012 18.7 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM37481.1 - 1.1e-06 28.7 0.0 0.006 16.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 GAM37481.1 - 1.1e-06 28.9 0.0 0.015 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAM37481.1 - 4.2e-06 27.1 0.0 0.077 13.3 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_16 PF13191.6 GAM37481.1 - 4.2e-06 27.2 0.1 0.14 12.5 0.0 3.6 4 0 0 4 4 3 2 AAA ATPase domain AAA_18 PF13238.6 GAM37481.1 - 1.2e-05 25.9 0.1 0.22 12.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 GAM37481.1 - 2.3e-05 24.8 0.0 0.63 10.5 0.0 4.3 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 GAM37481.1 - 4.5e-05 23.2 0.0 0.06 13.1 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 GAM37481.1 - 4.8e-05 23.6 0.0 0.17 12.0 0.0 3.0 2 0 0 2 2 2 2 Helicase HerA, central domain Dynamin_N PF00350.23 GAM37481.1 - 5.3e-05 23.3 0.3 0.005 16.9 0.0 3.2 3 0 0 3 3 2 1 Dynamin family AAA_15 PF13175.6 GAM37481.1 - 8.5e-05 22.4 0.9 0.39 10.4 0.0 3.0 2 2 1 3 3 2 2 AAA ATPase domain AAA_27 PF13514.6 GAM37481.1 - 0.00014 21.6 0.0 0.11 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAM37481.1 - 0.00022 21.4 0.2 0.52 10.5 0.0 3.3 4 0 0 4 4 2 1 AAA domain RNA_helicase PF00910.22 GAM37481.1 - 0.00024 21.5 0.0 0.84 10.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 GAM37481.1 - 0.00027 20.9 0.0 0.17 11.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain MeaB PF03308.16 GAM37481.1 - 0.0003 19.9 0.1 0.71 8.8 0.0 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 GAM37481.1 - 0.00054 19.2 0.0 1.4 8.0 0.0 3.0 3 0 0 3 3 3 2 G-protein alpha subunit AAA_30 PF13604.6 GAM37481.1 - 0.0013 18.5 0.0 2.3 7.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 GAM37481.1 - 0.0015 18.6 0.1 3.6 7.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 GAM37481.1 - 0.0015 18.3 0.0 1.7 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 GAM37481.1 - 0.004 17.4 0.0 1.1 9.5 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.17 GAM37481.1 - 0.009 15.8 0.1 4.5 7.0 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein HEAT_2 PF13646.6 GAM37481.1 - 0.0094 16.3 0.6 7 7.1 0.6 3.2 2 1 1 3 3 2 0 HEAT repeats cobW PF02492.19 GAM37481.1 - 0.0096 15.5 0.1 8.6 5.9 0.0 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 GAM37481.1 - 0.01 16.1 0.0 7.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 GAM37481.1 - 0.012 14.8 0.1 0.44 9.7 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 GAM37481.1 - 0.012 15.6 0.0 1.3 8.9 0.0 2.8 3 0 0 3 3 2 0 Rad17 P-loop domain CLP1_P PF16575.5 GAM37481.1 - 0.015 15.1 0.0 1.1 9.0 0.0 2.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MukB PF04310.12 GAM37481.1 - 0.015 15.1 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal HEAT PF02985.22 GAM37481.1 - 0.016 15.4 0.0 17 6.0 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat AAA_7 PF12775.7 GAM37481.1 - 0.02 14.4 0.1 4.2 6.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAM37481.1 - 0.022 14.5 0.0 12 5.6 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 GAM37481.1 - 0.024 14.6 0.2 3.1 7.7 0.0 2.9 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_13 PF13166.6 GAM37481.1 - 0.028 13.1 2.2 1.7 7.2 0.0 2.8 4 0 0 4 4 2 0 AAA domain AAA_5 PF07728.14 GAM37481.1 - 0.034 14.2 0.1 19 5.3 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 GAM37481.1 - 0.043 13.6 0.0 7.8 6.2 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_25 PF13481.6 GAM37481.1 - 0.047 13.3 0.1 3.5 7.2 0.0 3.1 4 0 0 4 4 2 0 AAA domain Mg_chelatase PF01078.21 GAM37481.1 - 0.051 12.9 0.3 3.4 7.0 0.0 3.1 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI Adaptin_N PF01602.20 GAM37481.1 - 0.053 12.1 0.2 2.1 6.8 0.0 2.6 1 1 2 3 3 3 0 Adaptin N terminal region Ploopntkinase3 PF18751.1 GAM37481.1 - 0.073 13.0 0.0 12 5.8 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF815 PF05673.13 GAM37481.1 - 0.084 12.0 0.0 11 5.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.25 GAM37481.1 - 0.089 12.4 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 GAM37481.1 - 0.1 11.9 0.3 5.8 6.2 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family Sugar_tr PF00083.24 GAM37482.1 - 1.1e-41 143.2 21.5 1.3e-40 139.6 21.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37482.1 - 2.9e-30 105.4 50.9 2.5e-27 95.7 31.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM37482.1 - 0.14 10.6 4.7 0.086 11.2 0.2 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) GntR PF00392.21 GAM37483.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family DUF2721 PF11026.8 GAM37483.1 - 8.1 6.4 10.6 9 6.2 5.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) MFS_1 PF07690.16 GAM37485.1 - 2.3e-43 148.5 32.9 2.3e-43 148.5 32.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM37485.1 - 2.8e-14 52.9 8.0 2.8e-14 52.9 8.0 2.4 1 1 0 2 2 2 1 Sugar (and other) transporter UL42 PF17638.2 GAM37485.1 - 0.13 12.2 0.2 0.42 10.6 0.2 1.8 1 0 0 1 1 1 0 HCMV UL42 OATP PF03137.20 GAM37485.1 - 0.9 7.7 18.2 3.7 5.7 0.5 3.2 2 2 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fas_alpha_ACP PF18325.1 GAM37486.1 - 4.3e-64 215.8 0.0 9.1e-64 214.7 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 GAM37486.1 - 2.5e-33 115.5 0.0 6.5e-33 114.1 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 GAM37486.1 - 3.1e-22 79.4 0.2 6.5e-22 78.3 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAM37486.1 - 7.9e-16 58.1 0.0 2.3e-15 56.6 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 GAM37486.1 - 1.1e-06 28.3 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37486.1 - 0.0034 17.0 0.0 0.0084 15.7 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM37486.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 KR domain Citrate_synt PF00285.21 GAM37487.1 - 1.9e-97 326.6 0.0 2.3e-97 326.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF1729 PF08354.10 GAM37488.1 - 5.2e-147 489.4 0.0 7.5e-147 488.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 GAM37488.1 - 1.9e-53 182.1 0.0 2.1e-51 175.3 0.0 2.4 2 0 0 2 2 2 1 Acyl transferase domain FAS_meander PF17951.1 GAM37488.1 - 1.2e-30 106.3 0.0 2.4e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 GAM37488.1 - 1.7e-30 106.5 0.0 3e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 GAM37488.1 - 5.7e-23 80.8 0.0 1.5e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 GAM37488.1 - 6e-06 26.3 0.1 1.5e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 GAM37488.1 - 4.3e-05 23.6 0.0 0.00014 22.0 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 GAM37488.1 - 0.0024 17.3 0.1 0.058 12.8 0.1 2.4 1 1 0 1 1 1 1 Nitronate monooxygenase Fungal_trans PF04082.18 GAM37489.1 - 2.9e-05 23.2 0.8 6.7e-05 22.1 0.8 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF72 PF01904.18 GAM37489.1 - 0.15 12.2 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF72 RTA1 PF04479.13 GAM37490.1 - 3.5e-67 226.0 14.1 5e-67 225.5 14.1 1.2 1 0 0 1 1 1 1 RTA1 like protein PAP2 PF01569.21 GAM37491.1 - 6.1e-21 74.6 6.3 2.2e-10 40.4 0.0 3.2 2 2 1 3 3 3 2 PAP2 superfamily Sulf_transp PF04143.14 GAM37491.1 - 4.5e-05 23.1 0.6 0.0064 16.1 0.2 2.1 2 0 0 2 2 2 2 Sulphur transport EMP70 PF02990.16 GAM37491.1 - 2.4 6.7 5.6 5.1 5.6 0.2 2.1 2 0 0 2 2 2 0 Endomembrane protein 70 DUF4231 PF14015.6 GAM37491.1 - 3.4 8.2 7.0 1.2 9.7 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF4282 PF14110.6 GAM37491.1 - 9.2 7.1 10.4 15 6.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) Fungal_trans_2 PF11951.8 GAM37492.1 - 0.00032 19.6 0.1 0.00043 19.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDH-cyt PF16010.5 GAM37493.1 - 2.8e-10 40.2 0.1 2.4e-09 37.2 0.1 2.1 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 GAM37493.1 - 5e-08 33.2 8.5 5e-08 33.2 8.5 2.5 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 GAM37493.1 - 2.7e-05 23.9 3.3 2.7e-05 23.9 3.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Zip PF02535.22 GAM37493.1 - 0.005 16.1 1.3 0.017 14.3 0.3 2.1 2 0 0 2 2 2 1 ZIP Zinc transporter Phage_holin_3_6 PF07332.11 GAM37493.1 - 0.7 10.0 3.6 24 5.0 1.8 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III RseC_MucC PF04246.12 GAM37493.1 - 1.2 9.0 6.3 0.24 11.4 1.5 2.2 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC NAD_binding_10 PF13460.6 GAM37494.1 - 8.5e-07 29.0 0.1 2.3e-06 27.6 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding DUF2999 PF11212.8 GAM37494.1 - 0.053 13.8 0.1 0.17 12.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) HTH_24 PF13412.6 GAM37494.1 - 0.12 12.0 0.1 0.46 10.1 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding AAA PF00004.29 GAM37495.1 - 1.6e-11 44.8 0.0 3.8e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM37495.1 - 3.2e-07 30.7 0.0 8.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAM37495.1 - 0.00016 21.4 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAM37495.1 - 0.00031 20.9 0.2 0.0016 18.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 GAM37495.1 - 0.00079 19.4 0.0 0.0025 17.8 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 GAM37495.1 - 0.00083 19.4 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 GAM37495.1 - 0.0058 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM37495.1 - 0.0063 16.9 0.0 0.025 15.0 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 GAM37495.1 - 0.038 13.9 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 GAM37495.1 - 0.05 13.8 0.4 0.34 11.1 0.0 2.6 4 0 0 4 4 3 0 AAA domain RsgA_GTPase PF03193.16 GAM37495.1 - 0.054 13.4 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 GAM37495.1 - 0.12 12.0 0.0 2 8.0 0.0 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 GAM37495.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 GAM37495.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SWIRM PF04433.17 GAM37496.1 - 9.2e-32 109.3 0.1 2.3e-31 108.0 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 GAM37496.1 - 4.4e-30 103.5 9.0 8.5e-30 102.6 9.0 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 GAM37496.1 - 3.3e-09 36.8 0.0 8e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM37496.1 - 2.7e-06 27.5 0.1 7.3e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAM37496.1 - 0.027 14.4 3.1 0.062 13.2 0.0 2.7 3 0 0 3 3 3 0 Myb DNA-binding like Phage_lysozyme2 PF18013.1 GAM37497.1 - 0.011 15.7 0.0 0.033 14.2 0.0 1.8 1 0 0 1 1 1 0 Phage tail lysozyme Myb_DNA-binding PF00249.31 GAM37497.1 - 0.15 12.3 0.9 1.9 8.8 0.0 2.9 3 0 0 3 3 3 0 Myb-like DNA-binding domain ResIII PF04851.15 GAM37498.1 - 8.3e-28 97.5 0.5 5.3e-27 94.9 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAM37498.1 - 5.7e-16 58.9 0.0 7.7e-15 55.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM37498.1 - 4.8e-10 39.5 0.0 1.5e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 GAM37498.1 - 3.3e-05 23.7 3.5 9.2e-05 22.2 0.0 2.9 3 1 0 3 3 3 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 GAM37498.1 - 0.0018 17.6 0.2 0.0042 16.4 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 GAM37498.1 - 0.067 13.6 0.2 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 GAM37498.1 - 0.12 12.6 0.0 1.1 9.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain Complex1_LYR PF05347.15 GAM37499.1 - 0.04 14.0 0.2 0.13 12.3 0.2 1.9 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DUF3271 PF11675.8 GAM37499.1 - 0.46 9.7 1.6 0.69 9.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3271) Ank_4 PF13637.6 GAM37500.1 - 2.1e-12 47.3 1.9 1.9e-09 37.9 0.1 4.1 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM37500.1 - 5.6e-06 26.9 0.1 0.03 14.9 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM37500.1 - 5.2e-05 23.3 0.5 0.012 16.0 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat KilA-N PF04383.13 GAM37500.1 - 0.001 18.9 0.2 0.0061 16.4 0.2 2.2 1 1 0 1 1 1 1 KilA-N domain Ank_5 PF13857.6 GAM37500.1 - 0.0014 18.9 0.4 0.16 12.3 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF4404 PF14357.6 GAM37500.1 - 0.12 13.1 0.7 0.43 11.3 0.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Baculo_PEP_C PF04513.12 GAM37500.1 - 0.16 12.0 0.5 0.61 10.1 0.1 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ank PF00023.30 GAM37500.1 - 1.4 9.5 3.0 8.3 7.1 0.1 3.3 4 0 0 4 4 4 0 Ankyrin repeat SVIP PF15811.5 GAM37500.1 - 5.7 7.5 7.3 0.39 11.2 1.2 2.2 2 0 0 2 2 2 0 Small VCP/p97-interacting protein DUF2141 PF09912.9 GAM37501.1 - 0.019 14.9 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) Mersacidin PF16934.5 GAM37501.1 - 0.057 13.2 0.7 0.057 13.2 0.7 2.1 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) Tyr_Deacylase PF02580.16 GAM37501.1 - 0.094 13.2 0.0 0.47 11.0 0.0 2.0 2 0 0 2 2 2 0 D-Tyr-tRNA(Tyr) deacylase TPR_1 PF00515.28 GAM37502.1 - 5.8e-09 35.4 3.2 0.019 14.8 0.6 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM37502.1 - 1.7e-08 34.0 0.1 0.0014 18.3 0.0 3.0 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.6 GAM37502.1 - 5.3e-08 32.7 3.3 0.00013 22.1 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM37502.1 - 8.2e-06 25.5 13.1 0.017 15.2 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM37502.1 - 1.9e-05 25.1 8.1 0.00088 19.7 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM37502.1 - 3.2e-05 24.5 0.7 0.0097 16.5 0.1 4.0 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM37502.1 - 0.00024 21.0 2.3 2 8.9 0.6 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM37502.1 - 0.00044 20.3 2.1 0.012 15.7 0.4 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM37502.1 - 0.0094 15.9 2.4 0.76 9.9 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM37502.1 - 0.013 16.2 0.4 0.013 16.2 0.4 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM37502.1 - 2 9.2 5.3 1.2e+02 3.7 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM37502.1 - 8.8 6.7 13.7 3.1 8.1 0.2 5.6 6 1 0 6 6 6 0 Tetratricopeptide repeat Fungal_trans PF04082.18 GAM37503.1 - 2.3e-07 30.1 0.2 3.8e-07 29.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM37503.1 - 1.1e-06 28.7 9.1 2.3e-06 27.6 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_deac_1 PF01522.21 GAM37503.1 - 0.17 11.8 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide deacetylase Pribosyltran_N PF13793.6 GAM37504.1 - 4.7e-40 136.1 0.1 4e-38 129.9 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAM37504.1 - 1.1e-33 116.8 0.1 1.7e-28 99.9 0.1 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAM37504.1 - 3.5e-07 29.9 0.1 0.00028 20.5 0.1 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain NAD_binding_7 PF13241.6 GAM37505.1 - 2e-33 114.9 0.0 3.4e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 GAM37505.1 - 1.9e-31 107.5 0.0 3e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 GAM37505.1 - 1.4e-14 53.2 0.1 1.4e-14 53.2 0.1 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.20 GAM37505.1 - 0.0019 18.3 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 GAM37505.1 - 0.0027 17.0 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GAM37505.1 - 0.0031 17.8 0.1 0.0067 16.7 0.1 1.6 1 1 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 GAM37505.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 GAM37505.1 - 0.029 13.7 2.2 0.11 11.9 0.1 2.3 2 1 1 3 3 3 0 ThiF family LSDAT_prok PF18171.1 GAM37505.1 - 0.054 12.7 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote DUF5444 PF17519.2 GAM37505.1 - 0.055 13.5 0.0 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5444) Sec7 PF01369.20 GAM37506.1 - 1.1e-71 240.3 0.4 4.5e-71 238.3 0.4 2.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GAM37506.1 - 2.1e-43 148.0 12.4 2.5e-43 147.7 6.6 3.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GAM37506.1 - 1.1e-33 114.9 12.4 1.5e-33 114.5 0.1 5.7 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 GAM37506.1 - 2.6e-17 63.0 4.3 1.4e-16 60.6 0.3 3.4 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 2-oxoacid_dh PF00198.23 GAM37507.1 - 2.2e-78 262.9 0.1 2.9e-78 262.5 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAM37507.1 - 4.3e-17 61.7 2.8 7.1e-17 61.0 0.5 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 GAM37507.1 - 1.9e-12 47.3 0.3 1.9e-12 47.3 0.3 2.8 3 0 0 3 3 3 1 e3 binding domain CENP-O PF09496.10 GAM37508.1 - 0.0045 17.0 0.3 0.0067 16.4 0.3 1.2 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component MIIP PF15734.5 GAM37508.1 - 0.03 13.8 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Migration and invasion-inhibitory ox_reductase_C PF08635.10 GAM37508.1 - 0.09 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain PLDc_2 PF13091.6 GAM37509.1 - 2.6e-15 56.5 0.0 3.1e-06 27.1 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 GAM37509.1 - 7.9e-15 54.3 3.2 4.1e-08 33.1 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Methyltransf_10 PF05971.12 GAM37510.1 - 8.7e-64 215.7 0.0 1.2e-63 215.3 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 GAM37510.1 - 3.4e-06 26.7 0.0 6.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAM37510.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF5353 PF17304.2 GAM37511.1 - 4.6e-25 87.1 4.0 4.6e-25 87.1 4.0 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5353) V-SNARE_C PF12352.8 GAM37511.1 - 1.4e-12 47.7 1.2 3.2e-12 46.5 1.2 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAM37511.1 - 0.0032 17.4 0.0 0.01 15.7 0.0 1.9 1 0 0 1 1 1 1 Sec20 TrbC PF04956.13 GAM37511.1 - 0.18 12.1 0.4 0.39 10.9 0.4 1.6 1 0 0 1 1 1 0 TrbC/VIRB2 family CbtA PF09490.10 GAM37511.1 - 0.39 10.4 3.1 0.7 9.6 3.1 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Ldh_1_C PF02866.18 GAM37512.1 - 7.4e-48 162.6 0.0 2.3e-47 161.0 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GAM37512.1 - 1.3e-44 151.7 0.1 4.3e-44 150.0 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAM37512.1 - 0.0018 17.4 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 GAM37512.1 - 0.075 12.3 0.0 0.97 8.7 0.0 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AAA PF00004.29 GAM37513.1 - 1.5e-16 61.0 0.0 4.4e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAM37513.1 - 0.00031 20.8 0.0 0.001 19.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAM37513.1 - 0.00093 19.5 0.6 0.012 15.9 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM37513.1 - 0.012 16.0 0.2 0.012 16.0 0.2 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 GAM37513.1 - 0.026 14.3 0.0 0.026 14.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 GAM37513.1 - 0.032 14.6 0.0 0.097 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 GAM37513.1 - 0.04 13.7 0.0 0.04 13.7 0.0 3.9 2 1 0 2 2 2 0 AAA domain Mem_trans PF03547.18 GAM37513.1 - 0.18 10.1 0.1 0.37 9.2 0.0 1.6 1 1 1 2 2 2 0 Membrane transport protein Macoilin PF09726.9 GAM37513.1 - 8.2 4.8 43.8 14 4.1 43.8 1.3 1 0 0 1 1 1 0 Macoilin family Fungal_trans_2 PF11951.8 GAM37514.1 - 2.1e-07 30.1 0.0 2.3e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Catalase PF00199.19 GAM37515.1 - 2.4e-134 448.3 2.2 1.3e-103 347.1 0.6 2.2 1 1 1 2 2 2 2 Catalase Catalase-rel PF06628.12 GAM37515.1 - 8.3e-10 38.7 0.0 2.3e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive Dyp_perox PF04261.12 GAM37516.1 - 7.2e-90 301.3 0.0 8.3e-90 301.1 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family Mob_synth_C PF06463.13 GAM37517.1 - 5e-37 126.7 0.1 2.7e-36 124.3 0.0 2.0 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 GAM37517.1 - 1.5e-25 90.5 0.0 2.4e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 GAM37517.1 - 9.1e-07 29.2 0.0 6.5e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 GAM37517.1 - 0.0067 16.6 0.0 0.021 15.0 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Oxidored_molyb PF00174.19 GAM37518.1 - 8e-43 146.0 0.0 1.4e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 GAM37518.1 - 4.8e-20 72.0 2.7 9e-20 71.1 2.7 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain His_Phos_2 PF00328.22 GAM37519.1 - 5e-05 22.8 0.1 0.017 14.5 0.0 2.8 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) HCMV_UL124 PF17609.2 GAM37519.1 - 8.3 6.6 10.3 1.2 9.3 4.9 2.3 2 0 0 2 2 2 0 Family of unknown function Peptidase_M3 PF01432.20 GAM37520.1 - 8.6e-134 447.2 0.0 1.1e-133 446.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Fungal_trans PF04082.18 GAM37520.1 - 3.5e-06 26.3 0.0 7.1e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M2 PF01401.18 GAM37520.1 - 0.03 13.0 0.0 0.058 12.0 0.0 1.4 1 0 0 1 1 1 0 Angiotensin-converting enzyme DIOX_N PF14226.6 GAM37521.1 - 1.9e-31 109.3 0.0 3e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM37521.1 - 9.8e-17 61.3 0.0 5.2e-16 59.0 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily GP40 PF11025.8 GAM37521.1 - 0.077 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Transp_cyt_pur PF02133.15 GAM37522.1 - 1.5e-87 294.2 40.7 1.7e-87 294.0 40.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HbrB PF08539.11 GAM37523.1 - 6e-50 169.5 2.0 6.4e-50 169.4 0.0 2.2 2 0 0 2 2 2 1 HbrB-like Gon7 PF08738.10 GAM37524.1 - 8.2e-13 48.4 1.0 8.2e-13 48.4 1.0 1.7 1 1 1 2 2 2 1 Gon7 family PRP9_N PF16958.5 GAM37524.1 - 0.026 14.6 0.1 0.031 14.3 0.1 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus Vps39_1 PF10366.9 GAM37525.1 - 6.1e-32 110.1 3.6 8.9e-31 106.4 0.0 3.7 3 1 1 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 GAM37525.1 - 4.3e-24 85.1 0.3 3e-23 82.4 0.0 2.5 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 GAM37525.1 - 1.9e-17 63.8 0.0 6.8e-17 62.0 0.0 1.8 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 GAM37525.1 - 5.5e-06 26.3 7.4 8.6e-06 25.7 3.8 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS PPR PF01535.20 GAM37525.1 - 0.025 14.8 0.3 0.86 10.0 0.0 3.4 3 0 0 3 3 3 0 PPR repeat TPR_1 PF00515.28 GAM37525.1 - 0.066 13.1 3.2 16 5.5 0.4 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC8 PF04049.13 GAM37525.1 - 0.12 12.4 0.9 0.37 10.8 0.0 2.2 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 PXA PF02194.15 GAM37525.1 - 0.3 11.0 3.1 0.19 11.7 0.3 2.0 3 0 0 3 3 3 0 PXA domain GlutR_dimer PF00745.20 GAM37525.1 - 0.42 11.1 3.2 1.7 9.1 0.3 2.8 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain 6PF2K PF01591.18 GAM37526.1 - 2.2e-76 256.1 0.0 3.5e-76 255.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAM37526.1 - 2e-39 135.3 0.0 3.2e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.22 GAM37526.1 - 1.9e-20 72.4 0.0 4.2e-15 55.3 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_33 PF13671.6 GAM37526.1 - 0.00013 22.1 0.0 0.00041 20.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain RRM_occluded PF16842.5 GAM37526.1 - 0.035 14.0 0.0 0.87 9.5 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif KTI12 PF08433.10 GAM37526.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Sugar_tr PF00083.24 GAM37527.1 - 3.7e-83 279.9 26.0 5.1e-83 279.4 26.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37527.1 - 1.5e-15 57.0 40.5 5e-14 52.0 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ketoacyl-synt PF00109.26 GAM37528.1 - 4.8e-68 229.5 0.2 1.1e-67 228.3 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAM37528.1 - 1.3e-59 201.1 0.9 1.3e-59 201.1 0.9 2.4 2 0 0 2 2 1 1 KR domain Acyl_transf_1 PF00698.21 GAM37528.1 - 6.7e-56 190.1 1.2 1.8e-55 188.7 1.2 1.8 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 GAM37528.1 - 5.4e-46 157.2 0.0 1.5e-45 155.7 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 GAM37528.1 - 9.8e-38 128.8 0.1 9.8e-38 128.8 0.1 2.3 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAM37528.1 - 1.5e-17 64.1 0.0 7.2e-17 61.9 0.0 2.3 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 GAM37528.1 - 7.8e-14 51.6 3.2 3.5e-13 49.4 0.1 2.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37528.1 - 1e-10 41.6 0.3 1e-10 41.6 0.3 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 GAM37528.1 - 6.3e-08 32.7 0.1 3.8e-07 30.1 0.1 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 GAM37528.1 - 1.1e-06 28.8 0.0 5e-06 26.8 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 GAM37528.1 - 0.0002 20.8 0.2 0.0029 17.0 0.0 2.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_zinc_N_2 PF13602.6 GAM37528.1 - 0.00077 20.5 0.0 0.0069 17.4 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM37528.1 - 0.0022 17.8 0.1 0.0068 16.3 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF915 PF06028.11 GAM37528.1 - 0.015 14.7 0.1 0.28 10.5 0.0 2.7 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) ThiF PF00899.21 GAM37528.1 - 0.055 12.8 0.5 2 7.7 0.1 2.4 2 0 0 2 2 2 0 ThiF family ACP_syn_III PF08545.10 GAM37528.1 - 0.059 13.2 0.4 0.22 11.4 0.4 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NAD_binding_4 PF07993.12 GAM37529.1 - 1.1e-28 100.1 0.0 3.1e-28 98.6 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 GAM37529.1 - 3e-21 75.5 0.0 4.8e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAM37529.1 - 8.8e-10 38.4 0.0 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAM37529.1 - 2.2e-08 34.3 0.1 8.7e-08 32.4 0.1 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 GAM37529.1 - 0.0007 18.8 0.0 0.3 10.2 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAM37529.1 - 0.0048 16.3 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAM37529.1 - 0.2 10.6 0.0 0.68 8.9 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hyd_65N_2 PF14498.6 GAM37530.1 - 0.012 15.5 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain TPR_1 PF00515.28 GAM37531.1 - 3.7e-50 165.8 29.2 5.4e-08 32.3 0.1 11.3 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAM37531.1 - 1.6e-45 149.6 20.9 1.9e-05 24.4 0.0 10.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.6 GAM37531.1 - 1.8e-36 121.3 19.1 6.8e-05 22.8 0.0 10.9 10 1 0 10 10 10 10 Tetratricopeptide repeat TPR_17 PF13431.6 GAM37531.1 - 2.4e-26 90.2 15.1 0.00039 20.6 0.1 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAM37531.1 - 1.1e-25 89.0 28.3 3.4e-06 26.6 0.2 10.0 6 3 4 10 10 10 6 TPR repeat TPR_16 PF13432.6 GAM37531.1 - 3e-25 88.6 6.7 5.2e-05 23.8 0.1 6.7 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 GAM37531.1 - 1.1e-24 86.7 16.1 0.00011 22.7 0.1 7.4 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.6 GAM37531.1 - 1.7e-24 84.4 17.5 5.9e-05 23.5 0.1 9.0 5 3 5 10 10 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 GAM37531.1 - 1.9e-22 79.4 20.0 4.2e-05 23.7 0.9 7.8 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 GAM37531.1 - 7.3e-21 73.4 18.4 0.0017 18.9 0.0 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAM37531.1 - 1.9e-18 65.1 15.8 0.0094 15.9 0.1 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAM37531.1 - 3.7e-16 59.0 12.4 0.00063 19.8 0.5 7.0 2 2 6 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM37531.1 - 2.3e-13 50.2 12.6 2.1e-08 34.3 2.8 4.0 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 GAM37531.1 - 2.2e-08 33.7 10.5 0.013 14.7 1.5 5.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 GAM37531.1 - 1.8e-06 27.8 5.8 0.019 14.7 0.0 4.1 3 2 0 4 4 3 3 Tetratricopeptide repeat-like domain BTAD PF03704.17 GAM37531.1 - 3.1e-06 27.7 6.7 0.01 16.2 0.1 3.5 3 0 0 3 3 3 2 Bacterial transcriptional activator domain TPR_MalT PF17874.1 GAM37531.1 - 0.0019 17.6 5.8 0.04 13.3 0.1 3.7 1 1 2 4 4 4 2 MalT-like TPR region DUF2225 PF09986.9 GAM37531.1 - 0.015 15.1 4.8 1.2 8.8 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_20 PF14561.6 GAM37531.1 - 0.074 13.4 4.0 0.67 10.3 0.0 3.9 3 1 2 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 GAM37531.1 - 1.3 9.2 19.4 14 5.8 1.8 5.8 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Aminotran_4 PF01063.19 GAM37533.1 - 4.7e-42 144.4 0.0 5.5e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Nucleo_P87 PF07267.11 GAM37534.1 - 0.057 12.3 5.8 0.072 11.9 5.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PD-C2-AF1 PF09310.10 GAM37534.1 - 0.77 9.1 16.3 1 8.7 16.3 1.1 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 PPP4R2 PF09184.11 GAM37534.1 - 1.8 8.1 12.1 2.4 7.7 12.1 1.1 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 GAM37534.1 - 6.2 6.5 13.4 9.5 5.9 13.4 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1720 PF08226.11 GAM37535.1 - 0.089 13.2 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1720) NUC173 PF08161.12 GAM37536.1 - 1.2e-79 266.7 0.1 1.8e-77 259.6 0.1 3.5 3 0 0 3 3 3 1 NUC173 domain HEAT PF02985.22 GAM37536.1 - 0.00049 20.1 1.4 3.7 8.0 0.1 4.2 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 GAM37536.1 - 0.0095 16.3 1.4 0.5 10.8 0.1 4.0 4 0 0 4 4 4 1 HEAT repeats LSM PF01423.22 GAM37537.1 - 1.4e-16 59.9 0.2 2.8e-16 58.9 0.2 1.5 1 0 0 1 1 1 1 LSM domain GMC_oxred_N PF00732.19 GAM37539.1 - 5.9e-35 121.1 0.0 8.4e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAM37539.1 - 0.00023 20.3 0.1 0.00035 19.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAM37539.1 - 0.00027 21.1 0.1 0.00087 19.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM37539.1 - 0.0012 18.0 0.1 0.0025 16.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM37539.1 - 0.0015 18.2 0.1 0.0037 16.9 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM37539.1 - 0.0048 16.2 0.1 0.0079 15.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM37539.1 - 0.0072 15.6 0.2 0.012 14.9 0.2 1.2 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.18 GAM37539.1 - 0.01 16.1 0.1 0.019 15.3 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 GAM37539.1 - 0.093 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM37539.1 - 0.11 12.5 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 GAM37539.1 - 0.15 10.7 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 GAM37539.1 - 0.22 10.3 0.1 0.42 9.4 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase CVNH PF08881.10 GAM37540.1 - 6.9e-05 23.5 0.0 8.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 CVNH domain Polysacc_deac_1 PF01522.21 GAM37541.1 - 4e-28 97.8 0.3 4e-27 94.6 0.1 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase PNP_UDP_1 PF01048.20 GAM37542.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphorylase superfamily Ribonuclease_3 PF00636.26 GAM37543.1 - 2.3e-41 140.7 0.0 1.7e-22 80.0 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GAM37543.1 - 2.1e-22 79.7 0.2 3.6e-11 43.3 0.0 3.8 3 0 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.29 GAM37543.1 - 4.2e-22 78.7 0.0 9.4e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.14 GAM37543.1 - 4.2e-20 71.7 0.1 9.7e-20 70.5 0.1 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 GAM37543.1 - 1.2e-18 67.5 0.1 2.8e-18 66.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM37543.1 - 9.3e-14 51.8 0.0 2.5e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.26 GAM37543.1 - 0.012 16.3 0.9 0.13 13.0 0.2 2.5 2 0 0 2 2 2 0 Double-stranded RNA binding motif PhoH PF02562.16 GAM37543.1 - 0.014 14.9 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 GAM37543.1 - 0.041 14.2 0.4 13 6.1 0.0 3.5 3 1 0 3 3 3 0 AAA domain Proteasome PF00227.26 GAM37544.1 - 6.6e-57 192.1 0.1 1.4e-32 112.8 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 GAM37544.1 - 8.9e-11 41.3 0.1 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RINGv PF12906.7 GAM37545.1 - 1.2e-08 35.0 4.1 3.2e-08 33.6 1.3 2.2 2 0 0 2 2 2 1 RING-variant domain PHD_4 PF16866.5 GAM37545.1 - 0.13 12.4 4.8 0.77 9.9 1.3 2.3 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 GAM37545.1 - 0.29 11.5 5.3 2.3 8.6 1.8 2.3 2 0 0 2 2 2 0 Ring finger domain zf-BED PF02892.15 GAM37545.1 - 1.5 8.9 4.7 0.36 10.9 0.9 1.9 2 0 0 2 2 2 0 BED zinc finger DUF1987 PF09345.10 GAM37546.1 - 0.18 11.5 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) Lyase_1 PF00206.20 GAM37547.1 - 1.7e-23 83.6 0.0 2.7e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 GAM37547.1 - 5.5e-17 62.1 0.0 3.1e-16 59.7 0.0 2.3 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Exo70 PF03081.15 GAM37548.1 - 5.2e-82 275.9 0.0 1.4e-81 274.5 0.0 1.6 2 0 0 2 2 2 1 Exo70 exocyst complex subunit DUF448 PF04296.13 GAM37548.1 - 0.0071 16.2 0.0 1.7 8.6 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF448) Bap31_Bap29_C PF18035.1 GAM37548.1 - 0.017 15.1 0.1 0.057 13.4 0.1 1.9 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Prominin PF05478.11 GAM37548.1 - 0.026 12.5 1.1 0.049 11.6 1.1 1.3 1 0 0 1 1 1 0 Prominin DUF4355 PF14265.6 GAM37548.1 - 0.06 13.6 0.7 0.49 10.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) FliS PF02561.14 GAM37548.1 - 0.36 11.1 1.7 2.2 8.6 0.8 2.8 3 1 0 3 3 3 0 Flagellar protein FliS FadA PF09403.10 GAM37548.1 - 3.5 8.2 5.3 11 6.6 0.1 3.4 3 0 0 3 3 3 0 Adhesion protein FadA PLA2_B PF01735.18 GAM37549.1 - 1.1e-24 86.8 0.0 2.5e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DSPc PF00782.20 GAM37550.1 - 3.4e-10 39.8 0.0 7.9e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM37550.1 - 7.7e-06 25.6 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAM37550.1 - 0.084 12.8 0.4 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 GAM37550.1 - 0.1 12.7 0.0 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate Sugar_tr PF00083.24 GAM37551.1 - 2.3e-80 270.7 27.4 4e-80 269.9 27.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37551.1 - 4.8e-28 98.1 30.1 1.5e-27 96.5 30.1 1.8 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM37551.1 - 3e-14 52.7 0.1 1.9e-13 50.1 0.0 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Mannosidase_ig PF17786.1 GAM37552.1 - 3.2e-17 62.9 0.2 8.6e-17 61.5 0.2 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 GAM37552.1 - 1.2e-11 45.3 0.0 2.7e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 GAM37552.1 - 0.0025 17.5 0.0 0.0074 16.0 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 GAM37552.1 - 0.033 13.3 0.2 0.085 11.9 0.2 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 GAM37552.1 - 0.037 13.9 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain PPR_2 PF13041.6 GAM37553.1 - 4.7e-11 42.7 0.0 0.0063 16.7 0.0 4.9 6 1 1 7 7 7 3 PPR repeat family PPR PF01535.20 GAM37553.1 - 2.4e-05 24.3 0.1 0.15 12.4 0.0 4.9 6 0 0 6 6 6 1 PPR repeat PET122 PF05476.11 GAM37553.1 - 0.00014 21.2 0.2 0.016 14.5 0.1 2.3 2 0 0 2 2 2 2 PET122 PPR_long PF17177.4 GAM37553.1 - 0.00021 20.8 0.0 1.7 8.0 0.0 3.4 3 1 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 GAM37553.1 - 0.00022 21.2 0.3 21 5.3 0.0 5.5 3 3 3 6 6 6 1 Pentatricopeptide repeat domain Guanylin PF02058.15 GAM37553.1 - 0.13 12.8 0.1 6.1 7.4 0.0 2.6 2 0 0 2 2 2 0 Guanylin precursor HTH_11 PF08279.12 GAM37553.1 - 0.14 12.1 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 HTH domain LSM PF01423.22 GAM37554.1 - 2.3e-17 62.4 0.0 3.5e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAM37554.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain BatD PF13584.6 GAM37555.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance AvrRpt-cleavage PF05627.11 GAM37555.1 - 0.059 12.7 2.2 1.5 8.2 0.7 2.6 2 0 0 2 2 2 0 Cleavage site for pathogenic type III effector avirulence factor Avr HemY_N PF07219.13 GAM37555.1 - 0.24 11.6 2.7 0.5 10.6 2.7 1.5 1 0 0 1 1 1 0 HemY protein N-terminus MHC_I_C PF06623.11 GAM37555.1 - 1.5 8.8 4.9 1.7 8.6 0.1 2.7 2 0 0 2 2 2 0 MHC_I C-terminus Hat1_N PF10394.9 GAM37556.1 - 2.9e-53 180.4 0.0 5.2e-53 179.6 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 GAM37556.1 - 0.08 13.2 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM37556.1 - 0.091 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM37556.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain p450 PF00067.22 GAM37558.1 - 1.7e-41 142.5 0.0 2.1e-31 109.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Amidohydro_3 PF07969.11 GAM37559.1 - 6.1e-76 256.8 0.4 6.9e-76 256.6 0.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 GAM37559.1 - 1.7e-08 34.2 0.0 3.6e-07 29.8 0.0 2.2 2 1 0 2 2 2 2 Amidohydrolase family Mito_carr PF00153.27 GAM37560.1 - 3.7e-11 42.8 0.9 4.7e-11 42.5 0.2 1.4 2 0 0 2 2 2 1 Mitochondrial carrier protein F-box-like PF12937.7 GAM37561.1 - 1.4e-11 44.1 0.3 1.4e-11 44.1 0.3 2.1 2 0 0 2 2 2 1 F-box-like WD40 PF00400.32 GAM37561.1 - 1.6e-07 31.9 3.8 0.0065 17.3 0.1 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box PF00646.33 GAM37561.1 - 9.8e-06 25.3 0.9 3.1e-05 23.7 0.9 2.0 1 0 0 1 1 1 1 F-box domain Fungal_trans_2 PF11951.8 GAM37561.1 - 5.8e-05 22.1 0.5 9.7e-05 21.3 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box_5 PF18511.1 GAM37561.1 - 0.00084 18.9 0.1 0.0016 18.0 0.1 1.5 1 0 0 1 1 1 1 F-box Zn_clus PF00172.18 GAM37561.1 - 0.025 14.7 1.7 0.065 13.4 1.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.22 GAM37562.1 - 2.8e-36 125.4 14.7 3.4e-28 98.8 6.5 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter DUF1856 PF08983.10 GAM37562.1 - 0.2 11.9 1.1 1 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) Ank_2 PF12796.7 GAM37563.1 - 2.2e-41 140.3 0.0 9.8e-13 48.5 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 GAM37563.1 - 6.8e-36 121.2 0.0 1.7e-07 31.4 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 GAM37563.1 - 3e-35 120.2 0.9 4.5e-07 30.3 0.0 8.4 5 1 4 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM37563.1 - 1.8e-34 117.4 0.7 2.4e-09 37.3 0.0 5.1 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM37563.1 - 8.9e-29 96.4 0.0 0.00012 22.2 0.0 7.9 8 1 0 8 8 8 5 Ankyrin repeat Fungal_lectin PF07938.12 GAM37563.1 - 2.3e-10 40.4 0.0 4.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Fungal fucose-specific lectin Mito_fiss_reg PF05308.11 GAM37565.1 - 0.17 11.9 2.9 0.44 10.6 0.7 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF155 PF02582.14 GAM37566.1 - 2.6e-51 174.2 0.0 4.4e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 GAM37566.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 NmrA PF05368.13 GAM37567.1 - 3.9e-35 121.5 0.3 4.7e-34 118.0 0.3 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM37567.1 - 1.9e-13 50.7 0.0 3.1e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAM37567.1 - 0.04 12.9 0.0 0.082 11.9 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family U3_snoRNA_assoc PF08297.11 GAM37568.1 - 1.4e-12 48.2 1.2 1.4e-12 48.2 1.2 4.5 3 1 1 4 4 4 1 U3 snoRNA associated CTK3 PF12243.8 GAM37569.1 - 6.1e-49 165.1 0.4 8.5e-49 164.7 0.4 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 GAM37569.1 - 3.2e-20 72.1 6.5 3.2e-20 72.1 6.5 1.9 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus DUF3873 PF12989.7 GAM37569.1 - 0.046 14.1 0.0 0.098 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) P5CR_dimer PF14748.6 GAM37570.1 - 8.4e-34 115.9 0.9 8.4e-34 115.9 0.9 1.6 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 GAM37570.1 - 8.1e-11 42.4 0.2 3.7e-10 40.2 0.0 2.3 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Voltage_CLC PF00654.20 GAM37571.1 - 2.9e-89 299.8 29.2 2.9e-89 299.8 29.2 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 GAM37571.1 - 0.00017 22.0 0.0 0.14 12.7 0.0 2.4 2 0 0 2 2 2 2 CBS domain AAA_5 PF07728.14 GAM37572.1 - 4.2e-128 422.0 0.1 4.1e-22 78.7 0.0 9.7 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 GAM37572.1 - 3.2e-48 162.3 4.9 2e-17 63.3 0.0 5.3 4 0 0 4 4 4 3 Midasin AAA lid domain AAA_7 PF12775.7 GAM37572.1 - 9.3e-31 106.7 1.8 4e-06 26.5 0.0 7.2 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA_lid_5 PF17865.1 GAM37572.1 - 1.9e-29 101.8 0.3 2.7e-28 98.1 0.1 3.2 3 0 0 3 3 1 1 Midasin AAA lid domain AAA PF00004.29 GAM37572.1 - 1.7e-28 99.7 0.0 0.00024 21.5 0.0 6.9 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 GAM37572.1 - 6.4e-28 97.2 0.0 6.3e-11 42.3 0.0 7.1 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM37572.1 - 8.1e-28 97.9 13.9 3.6e-05 24.2 0.1 8.5 7 1 0 7 7 6 5 AAA ATPase domain Dynein_heavy PF03028.15 GAM37572.1 - 4e-22 78.5 0.1 4e-06 26.9 0.0 7.8 9 0 0 9 9 7 4 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 GAM37572.1 - 9.2e-19 67.6 0.0 0.082 11.9 0.0 8.1 9 0 0 9 9 8 4 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 GAM37572.1 - 1.3e-18 67.6 1.1 0.04 14.2 0.0 8.7 9 0 0 9 9 6 4 AAA domain AAA_33 PF13671.6 GAM37572.1 - 4.5e-17 62.5 0.1 0.011 15.9 0.0 6.9 6 0 0 6 6 6 2 AAA domain Sigma54_activat PF00158.26 GAM37572.1 - 7.9e-17 61.5 0.0 0.028 14.1 0.1 5.9 6 0 0 6 6 5 4 Sigma-54 interaction domain AAA_14 PF13173.6 GAM37572.1 - 2.2e-16 60.1 0.0 0.0081 16.2 0.0 7.6 8 0 0 8 8 7 2 AAA domain FAD_binding_4 PF01565.23 GAM37572.1 - 1.2e-15 57.5 0.2 3.4e-15 56.0 0.2 1.9 1 0 0 1 1 1 1 FAD binding domain AAA_30 PF13604.6 GAM37572.1 - 6.9e-15 55.3 0.0 0.011 15.5 0.0 7.2 7 1 0 7 7 6 3 AAA domain TsaE PF02367.17 GAM37572.1 - 4.2e-14 52.6 1.3 0.11 12.5 0.0 6.7 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 GAM37572.1 - 6.8e-14 52.6 0.4 0.14 12.7 0.0 6.9 6 0 0 6 6 6 3 ABC transporter AAA_18 PF13238.6 GAM37572.1 - 1.7e-13 51.2 3.7 0.15 12.6 0.0 7.6 7 0 0 7 7 6 2 AAA domain RNA_helicase PF00910.22 GAM37572.1 - 1.4e-11 44.7 0.3 0.93 9.9 0.0 6.7 6 0 0 6 6 6 1 RNA helicase Sigma54_activ_2 PF14532.6 GAM37572.1 - 5.2e-11 42.8 0.4 0.00085 19.4 0.1 5.2 5 0 0 5 5 5 2 Sigma-54 interaction domain Rad17 PF03215.15 GAM37572.1 - 1.4e-10 41.4 0.8 0.0065 16.4 0.0 5.8 6 0 0 6 6 5 1 Rad17 P-loop domain Mg_chelatase PF01078.21 GAM37572.1 - 1.9e-10 40.5 0.4 12 5.3 0.0 8.2 8 0 0 8 8 8 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 GAM37572.1 - 3.5e-10 39.5 1.0 3.7 6.8 0.0 8.0 8 0 0 8 8 8 0 Zeta toxin RsgA_GTPase PF03193.16 GAM37572.1 - 7.6e-10 38.9 2.6 0.082 12.8 0.3 6.1 6 0 0 6 6 5 1 RsgA GTPase SRP54 PF00448.22 GAM37572.1 - 1.2e-09 38.1 3.4 0.21 11.2 0.0 5.7 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain AAA_19 PF13245.6 GAM37572.1 - 1.6e-09 38.3 2.1 3.6 7.9 0.1 6.7 6 0 0 6 6 6 0 AAA domain NACHT PF05729.12 GAM37572.1 - 2e-09 37.6 4.0 0.045 13.7 0.0 6.0 6 0 0 6 6 5 2 NACHT domain T2SSE PF00437.20 GAM37572.1 - 4.5e-09 35.8 3.2 0.0046 16.1 0.0 6.1 6 0 0 6 6 6 1 Type II/IV secretion system protein AAA_25 PF13481.6 GAM37572.1 - 1.2e-08 34.8 0.5 0.44 10.1 0.0 6.0 6 0 0 6 6 5 1 AAA domain RuvB_N PF05496.12 GAM37572.1 - 2.3e-08 34.0 2.6 0.6 9.8 0.0 6.7 7 0 0 7 7 6 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 GAM37572.1 - 4.7e-08 33.2 0.0 9.1 6.1 0.0 6.2 6 0 0 6 6 6 0 ATPase domain predominantly from Archaea TniB PF05621.11 GAM37572.1 - 7.3e-08 32.0 0.4 1.4 8.3 0.0 6.0 6 0 0 6 6 5 1 Bacterial TniB protein IstB_IS21 PF01695.17 GAM37572.1 - 4.1e-07 29.9 0.0 7 6.3 0.0 5.5 5 0 0 5 5 5 0 IstB-like ATP binding protein DUF815 PF05673.13 GAM37572.1 - 4.6e-07 29.2 1.3 0.69 9.0 0.1 5.5 6 0 0 6 6 6 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 GAM37572.1 - 1e-06 29.1 5.4 0.78 10.0 0.2 6.1 6 0 0 6 6 5 2 AAA domain AAA_29 PF13555.6 GAM37572.1 - 1.6e-06 27.7 0.5 26 4.7 0.1 6.4 6 0 0 6 6 6 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 GAM37572.1 - 2.6e-06 27.3 4.2 0.61 9.8 0.0 6.0 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 GAM37572.1 - 4.8e-06 26.4 0.0 5.1 6.8 0.0 5.7 6 0 0 6 6 6 0 AAA domain Roc PF08477.13 GAM37572.1 - 6.9e-06 26.3 2.5 6.5 7.0 0.0 6.4 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase BBE PF08031.12 GAM37572.1 - 9e-06 25.7 0.1 2.1e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like MMR_HSR1 PF01926.23 GAM37572.1 - 1.6e-05 24.9 3.1 0.38 10.9 0.0 5.8 6 0 0 6 6 6 1 50S ribosome-binding GTPase MCM PF00493.23 GAM37572.1 - 6.9e-05 22.0 0.2 0.99 8.4 0.0 4.7 5 0 0 5 5 5 1 MCM P-loop domain Bac_DnaA PF00308.18 GAM37572.1 - 0.00022 21.1 0.0 1.6 8.5 0.0 3.7 3 0 0 3 3 3 1 Bacterial dnaA protein SRPRB PF09439.10 GAM37572.1 - 0.00052 19.5 2.4 8.2 5.8 0.0 5.4 6 0 0 6 6 5 0 Signal recognition particle receptor beta subunit TIP49 PF06068.13 GAM37572.1 - 0.00067 19.0 1.0 4.5 6.4 0.0 4.5 5 0 0 5 5 5 0 TIP49 P-loop domain CPT PF07931.12 GAM37572.1 - 0.0015 18.4 0.9 0.93 9.3 0.0 5.4 6 1 0 6 6 3 1 Chloramphenicol phosphotransferase-like protein CbiA PF01656.23 GAM37572.1 - 0.0016 18.5 0.0 0.15 12.1 0.0 3.3 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_8 PF12780.7 GAM37572.1 - 0.0017 17.7 0.5 31 3.8 0.0 5.8 6 0 0 6 6 6 0 P-loop containing dynein motor region D4 Viral_helicase1 PF01443.18 GAM37572.1 - 0.0038 17.0 0.1 12 5.6 0.0 4.3 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.14 GAM37572.1 - 0.019 14.2 0.0 5.1 6.2 0.0 3.7 5 0 0 5 5 4 0 KAP family P-loop domain DnaB_C PF03796.15 GAM37572.1 - 0.02 14.2 3.2 2 7.7 0.1 4.1 4 0 0 4 4 4 0 DnaB-like helicase C terminal domain KTI12 PF08433.10 GAM37572.1 - 0.022 14.2 0.4 8.3 5.8 0.0 3.9 4 0 0 4 4 4 0 Chromatin associated protein KTI12 ATPase PF06745.13 GAM37572.1 - 0.026 13.9 0.6 17 4.7 0.0 4.0 4 0 0 4 4 3 0 KaiC NTPase_1 PF03266.15 GAM37572.1 - 0.038 13.9 8.0 1.3 8.9 0.0 5.2 5 0 0 5 5 5 0 NTPase PhoH PF02562.16 GAM37572.1 - 0.046 13.2 1.0 4.7 6.6 0.0 3.5 4 0 0 4 4 3 0 PhoH-like protein dNK PF01712.19 GAM37572.1 - 0.063 13.1 0.5 24 4.7 0.0 3.7 3 0 0 3 3 3 0 Deoxynucleoside kinase Septin PF00735.18 GAM37572.1 - 0.077 12.3 0.6 29 3.8 0.1 3.7 3 0 0 3 3 3 0 Septin ATP_bind_1 PF03029.17 GAM37572.1 - 0.077 12.8 7.6 28 4.4 0.1 5.7 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein PRK PF00485.18 GAM37572.1 - 0.086 12.6 0.3 2.2 7.9 0.0 3.2 5 0 0 5 5 2 0 Phosphoribulokinase / Uridine kinase family DUF3510 PF12022.8 GAM37572.1 - 0.14 12.5 1.7 8.4 6.8 0.1 4.6 5 0 0 5 5 2 0 Domain of unknown function (DUF3510) FeoB_N PF02421.18 GAM37572.1 - 0.18 11.4 5.0 2.6 7.6 0.0 4.4 5 0 0 5 5 5 0 Ferrous iron transport protein B tRNA_lig_kinase PF08303.11 GAM37572.1 - 0.19 11.8 1.9 8.7 6.4 0.1 3.2 3 0 0 3 3 2 0 tRNA ligase kinase domain cobW PF02492.19 GAM37572.1 - 0.76 9.3 7.8 28 4.2 0.1 5.0 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain Aldo_ket_red PF00248.21 GAM37573.1 - 4.7e-53 180.3 0.0 1.4e-45 155.8 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family MFS_1 PF07690.16 GAM37574.1 - 2.5e-29 102.3 26.7 3.5e-29 101.8 26.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM37574.1 - 0.0041 16.5 3.7 0.0065 15.8 3.7 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB LIP PF03583.14 GAM37575.1 - 7e-58 196.2 0.2 1e-57 195.7 0.2 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 GAM37575.1 - 7.2e-05 22.3 0.1 0.037 13.5 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 GAM37575.1 - 0.074 12.6 0.1 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family PRCC PF10253.9 GAM37576.1 - 2.1e-38 133.3 13.0 2.1e-38 133.3 13.0 2.4 1 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Lectin_leg-like PF03388.13 GAM37578.1 - 5.7e-67 225.4 0.0 7.5e-67 225.0 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 GAM37578.1 - 1.6e-08 34.8 0.2 2.2e-08 34.4 0.2 1.1 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 GAM37578.1 - 1.5e-05 24.7 0.1 0.0059 16.2 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain zf-Tim10_DDP PF02953.15 GAM37579.1 - 2e-19 69.0 0.1 3.2e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pkinase PF00069.25 GAM37580.1 - 6.9e-73 245.3 0.0 1e-72 244.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM37580.1 - 3.3e-37 128.2 0.0 4.8e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM37580.1 - 7.3e-06 25.5 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like LAP1C PF05609.12 GAM37580.1 - 2.6 7.0 23.7 3.6 6.6 23.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TFIIA PF03153.13 GAM37580.1 - 8.9 6.2 27.9 12 5.7 27.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RFC1 PF08519.12 GAM37581.1 - 1.7e-56 190.8 0.0 7.6e-56 188.6 0.0 2.1 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain CRIM PF16978.5 GAM37581.1 - 1.2e-36 125.9 0.0 2.9e-36 124.7 0.0 1.7 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 GAM37581.1 - 5.7e-26 90.9 0.1 2.6e-25 88.8 0.0 2.2 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology BRCT PF00533.26 GAM37581.1 - 1.7e-14 54.0 0.0 4.8e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 GAM37581.1 - 4.5e-09 36.8 1.7 7.2e-09 36.2 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAM37581.1 - 3.8e-05 23.7 0.0 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 GAM37581.1 - 0.00013 22.2 0.0 0.00034 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAM37581.1 - 0.00024 20.9 0.1 0.019 14.7 0.1 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAM37581.1 - 0.002 18.3 0.1 0.0054 16.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM37581.1 - 0.0023 18.4 0.1 0.016 15.6 0.1 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 GAM37581.1 - 0.023 14.4 0.0 0.072 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAM37581.1 - 0.052 14.1 0.1 0.17 12.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain TUG-UBL1 PF11470.8 GAM37581.1 - 0.1 12.8 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 TUG ubiquitin-like domain AAA_5 PF07728.14 GAM37581.1 - 0.14 12.2 0.1 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 GAM37581.1 - 0.16 11.7 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 GAM37581.1 - 0.24 11.6 1.3 0.28 11.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 GAM37581.1 - 5 6.8 10.0 2.6 7.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain Ribosomal_L16 PF00252.18 GAM37582.1 - 5.6e-30 104.0 0.2 1e-29 103.2 0.2 1.4 2 0 0 2 2 2 1 Ribosomal protein L16p/L10e CtaG_Cox11 PF04442.14 GAM37583.1 - 5.9e-61 204.9 0.0 1.5e-60 203.6 0.0 1.7 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DNA_pol3_delta2 PF13177.6 GAM37583.1 - 3.2e-10 40.0 0.0 6.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 GAM37583.1 - 3.1e-06 27.6 0.0 6.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM37583.1 - 2.2e-05 24.8 0.1 7.7e-05 23.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM37583.1 - 0.0031 17.9 0.5 0.019 15.4 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 GAM37583.1 - 0.0044 16.8 0.2 0.011 15.5 0.2 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 GAM37583.1 - 0.02 14.8 0.0 0.079 12.9 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain Rep_fac_C PF08542.11 GAM37583.1 - 0.026 14.9 0.0 0.064 13.7 0.0 1.7 1 0 0 1 1 1 0 Replication factor C C-terminal domain ABC_tran PF00005.27 GAM37583.1 - 0.03 14.8 0.0 0.072 13.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 GAM37583.1 - 0.045 12.6 0.0 0.045 12.6 0.0 1.6 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer CENP-Q PF13094.6 GAM37584.1 - 4.2e-45 154.0 8.2 8.2e-45 153.0 8.2 1.5 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit CYLD_phos_site PF16607.5 GAM37584.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphorylation region of CYLD, unstructured HLH PF00010.26 GAM37585.1 - 5.1e-08 32.7 0.0 1.3e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ORC6 PF05460.13 GAM37585.1 - 1.4 8.1 13.1 2.4 7.4 13.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RAP1 PF07218.11 GAM37585.1 - 7.4 4.7 9.2 10 4.3 9.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TMEM135_C_rich PF15982.5 GAM37586.1 - 0.003 18.1 1.2 0.011 16.4 0.3 2.4 3 1 0 3 3 3 1 N-terminal cysteine-rich region of Transmembrane protein 135 HEPN_SAV_6107 PF18726.1 GAM37586.1 - 0.15 12.6 7.2 1.2 9.7 1.8 2.6 3 0 0 3 3 3 0 SAV_6107-like HEPN Zn_clus PF00172.18 GAM37587.1 - 7.1e-06 26.0 9.2 1.3e-05 25.2 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ofd1_CTDD PF10637.9 GAM37587.1 - 0.037 13.4 0.2 0.053 12.9 0.2 1.3 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Cation_ATPase PF13246.6 GAM37587.1 - 0.058 13.5 0.2 9.1 6.4 0.4 2.5 2 0 0 2 2 2 0 Cation transport ATPase (P-type) SUIM_assoc PF16619.5 GAM37587.1 - 0.15 12.1 4.6 0.55 10.3 4.6 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 SPO22 PF08631.10 GAM37588.1 - 2e-05 24.3 10.3 0.0013 18.3 2.1 3.8 3 2 1 4 4 4 2 Meiosis protein SPO22/ZIP4 like TPR_5 PF12688.7 GAM37588.1 - 0.071 13.4 1.2 0.31 11.3 0.2 2.5 2 0 0 2 2 2 0 Tetratrico peptide repeat WD40 PF00400.32 GAM37589.1 - 2.6e-15 56.5 8.0 0.031 15.1 0.0 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM37589.1 - 0.0013 19.0 0.3 14 6.1 0.0 5.2 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_71 PF03659.14 GAM37590.1 - 4.2e-97 325.3 3.9 5.2e-97 325.0 3.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4387 PF14330.6 GAM37591.1 - 4.2e-33 114.0 0.0 9.9e-33 112.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 GAM37591.1 - 1.9e-17 63.1 0.0 6.8e-17 61.2 0.0 1.7 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA PFK PF00365.20 GAM37591.1 - 0.04 13.2 0.1 0.068 12.5 0.1 1.3 1 0 0 1 1 1 0 Phosphofructokinase MFS_1 PF07690.16 GAM37592.1 - 1.1e-23 83.8 19.9 4.5e-23 81.8 21.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Cyclase PF04199.13 GAM37592.1 - 2.7e-17 63.3 0.0 5.3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase MFS_1 PF07690.16 GAM37593.1 - 1.2e-17 63.9 35.8 1.6e-17 63.5 35.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Rgp1 PF08737.10 GAM37594.1 - 9.5e-143 476.3 0.0 1.9e-141 472.0 0.0 2.4 3 0 0 3 3 3 1 Rgp1 Neugrin PF06413.11 GAM37594.1 - 1.3e-12 48.2 1.5 1.3e-12 48.2 1.5 2.1 2 0 0 2 2 2 1 Neugrin Arrestin_N PF00339.29 GAM37594.1 - 4.8e-05 23.5 0.1 0.00018 21.6 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain MRP-L20 PF12824.7 GAM37594.1 - 1.6 8.9 26.3 0.017 15.3 15.8 2.6 2 1 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 Mob1_phocein PF03637.17 GAM37595.1 - 1.7e-72 242.9 0.1 2.3e-72 242.5 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.18 GAM37596.1 - 2e-46 158.2 4.3 2.5e-46 157.9 4.3 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF148 PF02520.17 GAM37596.1 - 0.059 13.5 0.6 0.31 11.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF1542 PF07564.11 GAM37596.1 - 1.8 8.7 6.6 1.8 8.7 0.4 2.9 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1542) Glyco_hydro_63 PF03200.16 GAM37597.1 - 1.8e-07 30.3 2.7 1.8e-07 30.3 2.7 4.2 4 1 0 4 4 4 1 Glycosyl hydrolase family 63 C-terminal domain DUF2730 PF10805.8 GAM37598.1 - 0.084 13.0 1.0 0.36 11.0 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Uds1 PF15456.6 GAM37598.1 - 0.16 12.2 9.5 0.36 11.0 9.4 1.6 1 1 0 1 1 1 0 Up-regulated During Septation DUF1635 PF07795.11 GAM37598.1 - 0.77 9.6 7.6 0.96 9.3 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Bromodomain PF00439.25 GAM37599.1 - 1.3e-06 28.4 0.0 1.7e-05 24.8 0.0 2.3 1 1 0 1 1 1 1 Bromodomain CASP_C PF08172.12 GAM37599.1 - 7.1 5.9 6.2 0.69 9.2 0.6 1.9 2 0 0 2 2 2 0 CASP C terminal Diphthamide_syn PF01866.17 GAM37600.1 - 2.4e-115 385.1 0.0 3.1e-115 384.8 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HMGL-like PF00682.19 GAM37601.1 - 5.1e-46 157.4 0.0 8.7e-46 156.6 0.0 1.4 1 1 0 1 1 1 1 HMGL-like PE PF00934.20 GAM37601.1 - 0.39 11.1 3.5 0.24 11.8 0.5 2.3 2 1 0 2 2 2 0 PE family DUF1674 PF07896.12 GAM37602.1 - 7.7e-19 67.9 2.2 7.7e-19 67.9 2.2 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1674) TFIIF_alpha PF05793.12 GAM37602.1 - 0.051 12.2 3.5 0.061 11.9 3.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Aminotran_3 PF00202.21 GAM37603.1 - 1.9e-108 362.8 0.0 2.4e-108 362.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAM37603.1 - 0.0014 17.8 0.0 0.0023 17.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Ank_2 PF12796.7 GAM37605.1 - 2.1e-54 182.0 11.5 1.6e-12 47.9 0.2 6.4 2 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM37605.1 - 1.6e-33 114.6 1.3 0.00017 22.1 0.0 8.5 6 1 3 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM37605.1 - 1e-30 105.4 1.7 3.9e-05 23.9 0.0 8.5 7 2 2 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 GAM37605.1 - 1.9e-28 97.6 4.5 0.00068 20.0 0.0 8.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.6 GAM37605.1 - 1.8e-23 80.0 2.6 0.01 16.3 0.0 9.7 11 0 0 11 11 11 4 Ankyrin repeat HET PF06985.11 GAM37605.1 - 1.6e-07 31.8 0.1 1.6e-07 31.8 0.1 3.0 2 1 1 3 3 3 1 Heterokaryon incompatibility protein (HET) Abhydrolase_3 PF07859.13 GAM37608.1 - 7.5e-34 117.4 0.0 8e-24 84.7 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold CLN3 PF02487.17 GAM37610.1 - 5.2e-122 407.7 0.1 5.9e-122 407.5 0.1 1.0 1 0 0 1 1 1 1 CLN3 protein DUF1772 PF08592.11 GAM37610.1 - 0.015 15.6 0.4 0.015 15.6 0.4 2.3 1 1 1 3 3 3 0 Domain of unknown function (DUF1772) Rxt3 PF08642.10 GAM37611.1 - 4e-43 147.2 0.6 2e-42 145.0 0.0 2.6 3 1 0 3 3 3 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 GAM37611.1 - 0.00062 19.8 0.0 0.0021 18.1 0.0 1.9 2 0 0 2 2 2 1 LCCL domain adh_short PF00106.25 GAM37612.1 - 1.5e-32 112.7 0.1 1.9e-32 112.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37612.1 - 8.8e-26 90.9 0.1 1.1e-25 90.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM37612.1 - 1e-08 35.3 0.1 1.4e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 KR domain FAD_binding_3 PF01494.19 GAM37613.1 - 7.3e-12 45.2 0.0 2e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM37613.1 - 0.00059 19.2 0.0 0.029 13.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_30C PF17189.4 GAM37613.1 - 0.12 12.6 0.0 0.59 10.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain Aldo_ket_red PF00248.21 GAM37614.1 - 4.4e-66 223.1 0.0 5.2e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Evf PF18270.1 GAM37614.1 - 0.048 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Virulence factor Evf Pro_racemase PF05544.11 GAM37615.1 - 4.2e-59 200.2 0.0 5.3e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Proline racemase Carn_acyltransf PF00755.20 GAM37616.1 - 1.4e-204 681.1 0.0 1.6e-204 680.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PriC PF07445.12 GAM37617.1 - 0.00071 19.5 2.1 0.00071 19.5 2.1 2.0 2 0 0 2 2 2 1 Primosomal replication protein priC DUF3138 PF11336.8 GAM37617.1 - 0.0021 16.8 6.1 0.0021 16.8 6.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3138) DUF2046 PF09755.9 GAM37617.1 - 0.0038 16.5 5.7 0.026 13.8 2.9 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Atg14 PF10186.9 GAM37617.1 - 0.028 13.5 2.9 0.057 12.5 0.6 2.2 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 GAM37617.1 - 0.28 11.0 0.1 0.28 11.0 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 GAM37617.1 - 0.36 11.5 13.6 4.7 7.9 0.1 2.5 2 0 0 2 2 2 0 SlyX DUF2968 PF11180.8 GAM37617.1 - 8 6.1 16.7 1.1 8.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Lectin_C PF00059.21 GAM37618.1 - 0.00089 20.0 1.7 0.015 16.0 0.1 2.9 3 0 0 3 3 3 1 Lectin C-type domain Sec62 PF03839.16 GAM37619.1 - 5.2e-72 241.9 0.3 5.2e-72 241.9 0.3 1.7 2 0 0 2 2 2 1 Translocation protein Sec62 Herpes_LMP1 PF05297.11 GAM37619.1 - 0.012 14.8 0.4 0.012 14.8 0.4 1.5 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DSBA PF01323.20 GAM37619.1 - 0.31 10.8 4.4 0.63 9.8 4.4 1.5 1 0 0 1 1 1 0 DSBA-like thioredoxin domain TFIIA PF03153.13 GAM37619.1 - 2.2 8.2 16.9 2.6 7.9 16.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit His_Phos_2 PF00328.22 GAM37620.1 - 1.1e-65 222.4 0.0 1.3e-65 222.2 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PH PF00169.29 GAM37621.1 - 0.027 15.0 0.0 0.072 13.6 0.0 1.8 1 0 0 1 1 1 0 PH domain Pyr_redox_2 PF07992.14 GAM37622.1 - 9.3e-10 38.2 0.0 5.8e-09 35.6 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM37622.1 - 0.0034 17.6 0.0 0.0081 16.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAM37622.1 - 0.02 13.6 0.0 0.033 12.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 GAM37622.1 - 0.056 12.5 0.0 0.72 8.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 GAM37622.1 - 0.1 13.0 0.0 8.5 6.9 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 GAM37622.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF726 PF05277.12 GAM37624.1 - 2.6e-116 388.3 2.7 3.5e-116 387.9 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 GAM37624.1 - 0.013 15.6 0.7 0.028 14.6 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain DUF900 PF05990.12 GAM37624.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.22 GAM37624.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.7 GAM37624.1 - 0.4 11.2 3.9 0.96 10.0 0.2 2.3 1 1 0 2 2 2 0 Alpha/beta hydrolase family Glu-tRNAGln PF02686.15 GAM37625.1 - 1.4e-09 38.1 0.2 1.2e-08 35.1 0.2 2.1 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Macoilin PF09726.9 GAM37625.1 - 0.019 13.6 0.1 0.026 13.1 0.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF4574 PF15141.6 GAM37625.1 - 0.038 13.9 0.2 0.066 13.1 0.2 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Aldedh PF00171.22 GAM37626.1 - 2.1e-183 610.1 0.1 2.4e-183 609.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SbsC_C PF18058.1 GAM37626.1 - 0.12 12.5 0.2 40 4.4 0.0 3.1 3 0 0 3 3 3 0 SbsC C-terminal domain ADH_N PF08240.12 GAM37627.1 - 2.9e-30 104.3 0.5 5.5e-30 103.5 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM37627.1 - 2.4e-23 82.5 0.1 4.1e-23 81.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM37627.1 - 0.0014 19.7 0.0 0.0023 19.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAM37627.1 - 0.0038 16.6 0.2 0.0068 15.8 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 GAM37627.1 - 0.022 14.2 0.4 0.041 13.3 0.4 1.4 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 GAM37627.1 - 0.066 12.5 1.3 0.098 11.9 1.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Gpr1_Fun34_YaaH PF01184.19 GAM37628.1 - 3.9e-31 108.3 19.8 4.8e-31 108.0 19.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family YlaC PF10777.9 GAM37628.1 - 1.4 8.8 5.3 2.9 7.7 5.3 1.5 1 0 0 1 1 1 0 Inner membrane protein YlaC Zn_clus PF00172.18 GAM37629.1 - 1.7e-10 40.8 12.3 4.1e-10 39.6 12.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DYW_deaminase PF14432.6 GAM37629.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases adh_short PF00106.25 GAM37631.1 - 8.8e-27 93.8 0.1 1.4e-25 89.9 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37631.1 - 9.4e-20 71.2 0.1 1.9e-18 66.9 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM37631.1 - 8.9e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 KR domain SNAP PF14938.6 GAM37632.1 - 1.8e-116 388.5 12.5 2e-116 388.3 12.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 GAM37632.1 - 3.7e-08 33.6 8.5 0.0002 21.6 0.5 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAM37632.1 - 0.0019 18.7 8.7 2 9.2 0.1 5.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM37632.1 - 0.0041 17.1 9.4 3.7 7.8 0.7 5.2 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM37632.1 - 0.14 12.5 0.7 0.14 12.5 0.7 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM37632.1 - 0.44 10.8 19.3 1.5 9.1 0.1 6.7 4 1 2 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM37632.1 - 1 9.3 17.6 2.1 8.3 0.1 5.9 5 1 2 7 7 7 0 Tetratricopeptide repeat BING4CT PF08149.11 GAM37633.1 - 2.8e-39 132.8 0.0 1.6e-35 120.7 0.0 3.4 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 GAM37633.1 - 1.4e-08 34.9 0.1 2.4 8.5 0.0 5.9 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAM37633.1 - 0.0013 19.5 0.0 2.3 9.2 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 GAM37633.1 - 0.028 13.5 0.0 0.077 12.0 0.0 1.7 1 1 1 2 2 2 0 Coatomer WD associated region RIBIOP_C PF04950.12 GAM37634.1 - 3.3e-111 371.4 0.1 1.6e-110 369.1 0.0 2.0 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 GAM37634.1 - 2.4e-21 75.6 0.0 5.7e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain cobW PF02492.19 GAM37635.1 - 2.6e-34 118.3 0.0 3.1e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 GAM37635.1 - 2.6e-05 23.3 0.0 0.011 14.7 0.0 2.0 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 GAM37635.1 - 0.013 15.1 0.0 6.3 6.3 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain CbiA PF01656.23 GAM37635.1 - 0.047 13.7 0.0 0.086 12.9 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 GAM37635.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase ResIII PF04851.15 GAM37635.1 - 0.079 13.0 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 GAM37635.1 - 0.081 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 GAM37635.1 - 0.17 12.3 0.0 0.24 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GAM37635.1 - 0.22 11.4 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea zf-AN1 PF01428.16 GAM37636.1 - 0.00012 22.2 9.3 0.0002 21.5 9.3 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger F-box PF00646.33 GAM37637.1 - 2.1e-05 24.3 0.1 8.9e-05 22.3 0.1 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAM37637.1 - 0.00039 20.3 0.2 0.0013 18.6 0.2 1.9 1 0 0 1 1 1 1 F-box-like Bcr-Abl_Oligo PF09036.10 GAM37637.1 - 0.076 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain LIM_bind PF01803.16 GAM37638.1 - 1e-56 192.2 0.0 1e-56 192.2 0.0 4.4 2 1 0 2 2 2 1 LIM-domain binding protein AAA PF00004.29 GAM37639.1 - 5.2e-42 143.4 0.0 7.2e-39 133.2 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM37639.1 - 2.5e-11 43.2 0.1 7e-11 41.8 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 GAM37639.1 - 2.2e-05 24.9 0.1 0.0018 18.7 0.0 3.3 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 GAM37639.1 - 0.0001 22.1 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAM37639.1 - 0.00011 22.5 0.3 0.053 13.8 0.1 3.5 2 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 GAM37639.1 - 0.00046 20.4 0.0 0.0018 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 GAM37639.1 - 0.0013 18.0 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 GAM37639.1 - 0.0033 17.4 0.0 0.0079 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 GAM37639.1 - 0.0079 16.2 0.0 0.05 13.6 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 GAM37639.1 - 0.0093 16.2 0.1 0.078 13.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAM37639.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAM37639.1 - 0.024 14.0 0.1 0.054 12.9 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GAM37639.1 - 0.039 14.3 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 GAM37639.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAM37639.1 - 0.071 13.7 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 GAM37639.1 - 0.11 12.9 0.0 0.34 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 GAM37639.1 - 0.13 12.4 0.0 0.65 10.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TniB PF05621.11 GAM37639.1 - 0.14 11.6 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 GAM37639.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4050 PF13259.6 GAM37640.1 - 3e-55 187.4 1.1 3e-55 187.4 1.1 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF4050) DUF3237 PF11578.8 GAM37641.1 - 2.5e-33 115.0 0.0 3.4e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.15 GAM37641.1 - 0.0014 18.6 6.3 0.31 11.1 1.3 2.4 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.7 GAM37641.1 - 0.083 13.2 4.8 5.5 7.4 0.6 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS91 PF14319.6 GAM37641.1 - 0.19 11.8 9.5 1.4 9.0 2.3 2.3 2 0 0 2 2 2 0 Transposase zinc-binding domain NAT PF04768.13 GAM37642.1 - 1.2e-54 184.5 0.1 2.4e-54 183.5 0.1 1.5 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 GAM37642.1 - 5.7e-30 104.2 0.0 1.9e-29 102.6 0.0 2.0 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 GAM37642.1 - 7.2e-28 97.8 0.0 1.3e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family Rad21_Rec8_N PF04825.13 GAM37642.1 - 3.2e-24 85.2 0.0 6.5e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 GAM37642.1 - 0.0005 19.3 0.2 0.0012 18.1 0.2 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DapB_N PF01113.20 GAM37642.1 - 0.049 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus AphA_like PF14557.6 GAM37642.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator NmrA PF05368.13 GAM37643.1 - 3.4e-10 39.9 0.0 4.2e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM37643.1 - 1.8e-07 31.2 0.1 2.9e-07 30.6 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM37643.1 - 6.7e-05 22.5 0.0 0.00015 21.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 GAM37643.1 - 0.0018 17.8 0.0 0.0033 16.9 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37643.1 - 0.0066 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HEM4 PF02602.15 GAM37643.1 - 0.062 12.6 0.2 0.26 10.6 0.2 1.8 1 1 1 2 2 2 0 Uroporphyrinogen-III synthase HemD Hydrolase PF00702.26 GAM37643.1 - 0.084 13.1 0.1 0.46 10.7 0.1 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ELFV_dehydrog PF00208.21 GAM37643.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Synaptobrevin PF00957.21 GAM37644.1 - 3.2e-34 116.6 1.7 3.6e-34 116.4 1.7 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 GAM37644.1 - 0.057 14.1 0.0 0.098 13.3 0.0 1.4 1 1 0 1 1 1 0 AT-hook-containing transcription factor adh_short PF00106.25 GAM37645.1 - 2.2e-43 148.0 0.0 2.6e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37645.1 - 5.8e-30 104.6 0.0 7e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM37645.1 - 2.1e-10 40.8 0.0 2.8e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAM37645.1 - 0.00011 22.2 0.1 0.00026 21.0 0.1 1.7 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 GAM37645.1 - 0.0045 16.5 0.0 0.0093 15.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GAM37645.1 - 0.016 15.4 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 GAM37645.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_28 PF00295.17 GAM37646.1 - 3.3e-43 148.0 9.8 6.2e-43 147.1 9.8 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 GAM37646.1 - 0.00071 19.5 9.6 0.00071 19.5 9.6 2.3 2 1 0 2 2 2 1 Right handed beta helix region adh_short PF00106.25 GAM37647.1 - 1.3e-37 129.2 0.2 1.7e-37 128.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37647.1 - 6.7e-30 104.4 0.1 8e-30 104.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM37647.1 - 1.6e-06 28.2 0.6 3.6e-06 27.0 0.6 1.5 1 1 0 1 1 1 1 KR domain ACT_7 PF13840.6 GAM37647.1 - 0.026 14.3 0.1 0.099 12.5 0.0 2.0 2 0 0 2 2 2 0 ACT domain Epimerase PF01370.21 GAM37647.1 - 0.085 12.3 1.2 0.44 10.0 1.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 GAM37648.1 - 3.2e-08 33.6 17.6 7.6e-08 32.4 10.3 3.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 GAM37648.1 - 0.00013 22.2 13.2 0.0028 18.0 5.3 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM37648.1 - 0.00052 20.3 2.7 0.00052 20.3 2.7 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAM37648.1 - 0.02 15.7 3.4 0.02 15.7 3.4 4.2 5 0 0 5 5 5 0 C2H2-type zinc finger FMO-like PF00743.19 GAM37649.1 - 1.7e-13 49.9 1.5 2.5e-12 46.0 0.3 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 GAM37649.1 - 2.1e-11 43.9 0.0 5.5e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM37649.1 - 7.8e-08 32.3 0.0 0.011 15.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM37649.1 - 4.9e-06 26.0 0.0 0.0008 18.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM37649.1 - 3.4e-05 23.9 0.9 0.004 17.2 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAM37649.1 - 0.00015 21.2 0.0 0.0049 16.2 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM37649.1 - 0.00089 18.5 0.2 0.06 12.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Glu_dehyd_C PF16912.5 GAM37649.1 - 0.0078 15.7 0.1 6.7 6.1 0.0 3.1 3 0 0 3 3 3 1 Glucose dehydrogenase C-terminus Thi4 PF01946.17 GAM37649.1 - 0.0082 15.4 0.0 0.33 10.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 GAM37649.1 - 0.068 12.2 0.0 2.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 GAM37649.1 - 0.15 11.3 0.0 10 5.3 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase p450 PF00067.22 GAM37650.1 - 3.4e-49 167.9 0.0 4.4e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.13 GAM37651.1 - 2.4e-20 73.3 0.0 9.5e-14 51.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM37651.1 - 1.1e-09 38.1 0.0 1.3e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 GAM37651.1 - 5.6e-05 22.2 0.0 0.00037 19.5 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 GAM37651.1 - 0.00064 18.7 0.0 0.00082 18.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 GAM37651.1 - 0.0014 18.2 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.8 GAM37651.1 - 0.0065 15.8 0.0 0.02 14.2 0.0 1.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 GAM37651.1 - 0.0086 15.9 0.0 0.18 11.6 0.0 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 GAM37651.1 - 0.018 14.6 0.2 0.56 9.8 0.2 2.8 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Propep_M14 PF02244.16 GAM37651.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase activation peptide AXE1 PF05448.12 GAM37651.1 - 0.12 11.0 0.0 0.23 10.1 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Cellulase PF00150.18 GAM37652.1 - 2.6e-57 194.4 0.3 3.6e-57 194.0 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 GAM37652.1 - 6.9e-12 45.1 12.6 2.6e-11 43.3 12.6 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Ribosomal_S2 PF00318.20 GAM37652.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S2 DUF3439 PF11921.8 GAM37652.1 - 0.76 9.8 11.5 1.8 8.6 11.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ADH_N PF08240.12 GAM37653.1 - 2.1e-19 69.4 3.1 2.1e-19 69.4 3.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM37653.1 - 2.5e-11 43.7 0.0 4.9e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAM37653.1 - 0.00011 21.6 0.0 0.00032 20.1 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAM37653.1 - 0.00018 20.9 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAM37653.1 - 0.015 15.4 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 GAM37653.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 GAM37653.1 - 0.12 13.2 0.0 0.37 11.6 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold p450 PF00067.22 GAM37655.1 - 4.1e-59 200.5 0.0 4.8e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Smac_DIABLO PF09057.10 GAM37655.1 - 0.059 12.7 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases SRP_TPR_like PF17004.5 GAM37655.1 - 0.13 12.2 0.3 0.26 11.3 0.3 1.5 1 0 0 1 1 1 0 Putative TPR-like repeat p450 PF00067.22 GAM37656.1 - 1.8e-33 116.0 0.0 2.5e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 SQHop_cyclase_C PF13243.6 GAM37657.1 - 9e-114 379.9 3.2 1.7e-109 365.8 0.9 3.4 3 1 0 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 GAM37657.1 - 1.1e-98 330.0 0.1 6.5e-92 307.7 0.0 3.2 3 0 0 3 3 3 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 GAM37657.1 - 2.1e-24 84.9 12.9 5.4e-07 29.2 0.1 6.4 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 GAM37657.1 - 1.5e-06 27.5 0.4 0.29 10.1 0.0 4.2 3 1 0 4 4 4 2 A-macroglobulin TED domain Pec_lyase PF09492.10 GAM37657.1 - 0.0038 16.6 0.0 0.18 11.1 0.0 2.8 2 1 1 3 3 3 1 Pectic acid lyase MFS_1 PF07690.16 GAM37659.1 - 1.2e-41 142.8 39.8 1.7e-40 139.0 39.8 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM37659.1 - 8.1e-14 50.9 22.2 1.2e-13 50.4 22.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM37659.1 - 5.9e-05 22.1 15.2 5.9e-05 22.1 15.2 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 GAM37659.1 - 0.0013 17.7 11.6 0.0013 17.7 10.0 1.8 1 1 0 1 1 1 1 MFS_1 like family FAD_binding_3 PF01494.19 GAM37660.1 - 6.4e-20 71.7 0.1 1.8e-14 53.8 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAM37660.1 - 5.1e-06 26.6 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM37660.1 - 0.00072 18.9 0.0 0.0028 17.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM37660.1 - 0.057 13.4 0.1 0.17 11.9 0.1 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAM37660.1 - 0.11 11.6 0.0 0.92 8.5 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 GAM37660.1 - 0.15 11.6 0.1 1.1 8.8 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM37660.1 - 0.19 10.4 0.0 0.44 9.2 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein FSH1 PF03959.13 GAM37661.1 - 3.5e-19 69.3 0.0 6.4e-19 68.5 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) UDPGT PF00201.18 GAM37662.1 - 1.9e-19 69.9 0.0 3.3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_hydro_3 PF00933.21 GAM37663.1 - 1.9e-34 119.5 0.0 3.7e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM37663.1 - 7.1e-24 83.7 0.0 1.4e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 GAM37663.1 - 1.6e-17 64.2 0.0 5.9e-15 55.8 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Zn_clus PF00172.18 GAM37664.1 - 0.0052 16.9 1.7 0.013 15.7 1.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.6 GAM37665.1 - 2.9e-11 43.2 0.0 8.1e-11 41.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAM37665.1 - 3.4e-10 39.0 0.0 1.8e-09 36.6 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 GAM37665.1 - 6e-10 39.2 0.0 6.3e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM37665.1 - 2.2e-09 37.0 0.1 1.2e-07 31.3 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM37665.1 - 8.5e-08 31.7 0.1 0.0001 21.7 0.0 2.6 3 0 0 3 3 3 2 Thi4 family DAO PF01266.24 GAM37665.1 - 3.9e-05 23.4 0.7 0.0079 15.8 0.3 3.4 3 1 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAM37665.1 - 0.00045 19.5 0.1 0.0068 15.6 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 GAM37665.1 - 0.00051 19.2 0.0 0.018 14.1 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 GAM37665.1 - 0.001 19.6 0.1 0.072 13.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM37665.1 - 0.0016 17.6 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 GAM37665.1 - 0.022 15.2 0.0 0.063 13.7 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 GAM37665.1 - 0.047 13.7 0.1 0.23 11.5 0.0 2.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase ketoacyl-synt PF00109.26 GAM37666.1 - 3.3e-72 243.1 0.0 7.1e-72 242.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAM37666.1 - 4.1e-60 202.8 0.1 2.1e-59 200.4 0.0 2.2 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 GAM37666.1 - 3.8e-58 197.1 0.0 1.1e-57 195.6 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 GAM37666.1 - 1.1e-34 119.0 0.0 2.6e-34 117.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 GAM37666.1 - 5.1e-34 118.2 2.0 8.4e-29 101.1 0.8 2.3 1 1 1 2 2 2 2 Acyl transferase domain Methyltransf_12 PF08242.12 GAM37666.1 - 2.1e-20 73.3 0.0 6.1e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAM37666.1 - 2.5e-16 60.1 0.0 1.2e-15 57.9 0.0 2.2 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 GAM37666.1 - 3.8e-16 60.3 0.0 2.5e-14 54.5 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAM37666.1 - 7.8e-14 51.8 0.1 5.4e-13 49.1 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 GAM37666.1 - 1.8e-10 41.4 0.0 1.7e-09 38.3 0.0 2.8 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM37666.1 - 1.2e-09 38.2 0.0 2.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM37666.1 - 5.3e-09 36.6 0.0 2e-08 34.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 GAM37666.1 - 2.7e-06 27.0 1.7 5.9e-06 25.9 0.0 2.4 3 0 0 3 3 3 1 short chain dehydrogenase ADH_N PF08240.12 GAM37666.1 - 2.8e-06 27.2 0.1 6.1e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 GAM37666.1 - 7.1e-06 25.5 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAM37666.1 - 7.7e-06 25.8 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 GAM37666.1 - 0.00011 22.5 0.0 0.0024 18.2 0.1 2.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 GAM37666.1 - 0.012 14.9 0.1 0.03 13.7 0.1 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain MFS_1 PF07690.16 GAM37667.1 - 2.3e-30 105.7 65.5 6.8e-23 81.2 43.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 GAM37668.1 - 0.00036 20.3 0.4 0.00089 19.1 0.1 1.9 2 0 0 2 2 2 1 F-box-like p450 PF00067.22 GAM37669.1 - 1.4e-66 225.1 0.0 1.8e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_4 PF07993.12 GAM37670.1 - 1.4e-32 112.9 0.0 2e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAM37670.1 - 6.1e-23 81.1 0.0 9.7e-23 80.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAM37670.1 - 3e-10 40.0 0.0 6.3e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 GAM37670.1 - 3.1e-10 39.6 0.0 6.8e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM37670.1 - 1.5e-06 28.2 12.2 3e-06 27.3 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PP-binding PF00550.25 GAM37670.1 - 6.6e-05 23.2 0.0 0.00025 21.3 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 GAM37670.1 - 0.0001 21.8 0.0 0.00027 20.5 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase BTB PF00651.31 GAM37671.1 - 1.3e-24 86.6 0.0 9.6e-14 51.6 0.8 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 GAM37671.1 - 2.4e-08 34.3 0.0 6.3e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM37671.1 - 7.1e-07 29.7 0.0 1.5e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM37671.1 - 1.2e-06 28.7 0.0 3.3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 GAM37671.1 - 2.9e-05 24.3 0.0 0.003 17.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 GAM37671.1 - 0.0043 17.5 0.2 0.085 13.5 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat DUF3342 PF11822.8 GAM37671.1 - 0.051 13.8 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Pkinase PF00069.25 GAM37672.1 - 1.1e-54 185.6 0.1 2.7e-34 118.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM37672.1 - 4.1e-35 121.3 0.0 3.6e-24 85.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM37672.1 - 0.0051 15.6 2.0 0.2 10.4 0.0 2.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAM37672.1 - 0.042 13.2 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 GAM37672.1 - 0.11 12.4 0.0 1.9 8.3 0.0 2.4 1 1 0 2 2 2 0 Phosphotransferase enzyme family DUF3896 PF13035.6 GAM37672.1 - 4.4 7.5 6.4 0.5 10.6 0.7 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3896) Wbp11 PF09429.10 GAM37673.1 - 1.6e-21 76.5 15.9 1.6e-21 76.5 15.9 2.5 2 1 0 2 2 2 1 WW domain binding protein 11 DUF2167 PF09935.9 GAM37673.1 - 0.22 10.7 2.0 1.3 8.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) NpwBP PF12622.7 GAM37673.1 - 0.28 12.0 2.4 3.4 8.5 0.1 3.0 2 0 0 2 2 2 0 mRNA biogenesis factor Cobalamin_bind PF01122.19 GAM37674.1 - 0.0023 16.9 0.3 0.0032 16.4 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein DUF1664 PF07889.12 GAM37674.1 - 0.0098 15.9 1.2 0.055 13.5 1.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Nbl1_Borealin_N PF10444.9 GAM37674.1 - 0.022 14.4 1.5 0.26 10.9 0.4 2.6 2 1 0 2 2 2 0 Nbl1 / Borealin N terminal Baculo_PEP_C PF04513.12 GAM37674.1 - 0.022 14.8 0.3 1.3 9.0 0.3 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 GAM37674.1 - 0.028 14.3 2.7 0.099 12.5 1.5 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4407 PF14362.6 GAM37674.1 - 0.048 13.0 1.9 0.051 12.9 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSBP1 PF06825.12 GAM37674.1 - 0.056 13.3 0.9 2.6 8.0 0.2 2.4 2 0 0 2 2 2 0 Heat shock factor binding protein 1 CdvA PF18822.1 GAM37674.1 - 0.06 13.2 1.2 1.1 9.1 1.2 2.3 1 1 0 1 1 1 0 CdvA-like coiled-coil domain Fib_alpha PF08702.10 GAM37674.1 - 0.23 11.6 1.0 0.45 10.7 1.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CorA PF01544.18 GAM37674.1 - 0.98 8.7 4.1 1.3 8.2 4.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Rpr2 PF04032.16 GAM37675.1 - 9.3e-25 86.7 0.3 1.9e-24 85.8 0.3 1.5 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain NECFESHC PF16621.5 GAM37675.1 - 0.084 12.9 2.8 0.23 11.4 2.8 1.8 1 0 0 1 1 1 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 GNT-I PF03071.15 GAM37675.1 - 0.14 10.9 0.8 0.18 10.6 0.8 1.1 1 0 0 1 1 1 0 GNT-I family DEAD PF00270.29 GAM37676.1 - 2.5e-36 125.1 0.1 4.6e-36 124.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM37676.1 - 2e-26 92.5 0.0 6.8e-24 84.4 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 GAM37676.1 - 3.5e-08 33.6 0.0 7.1e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAM37676.1 - 0.0014 18.1 0.1 0.0058 16.0 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Lipase_GDSL PF00657.22 GAM37677.1 - 2.7e-11 43.8 0.1 3.5e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAM37677.1 - 9.6e-07 29.4 2.6 4.6e-06 27.1 2.6 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family T5orf172 PF10544.9 GAM37678.1 - 2e-15 57.2 0.6 2e-15 57.2 0.6 2.0 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 GAM37678.1 - 7.3e-06 26.6 0.7 1.8e-05 25.3 0.7 1.7 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 Red1 PF07964.11 GAM37678.1 - 0.39 8.9 6.8 0.51 8.5 6.8 1.1 1 0 0 1 1 1 0 Rec10 / Red1 SOG2 PF10428.9 GAM37678.1 - 2.7 7.1 17.1 3.8 6.6 17.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ApbA PF02558.16 GAM37679.1 - 2.1e-23 82.6 0.0 3.1e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 GAM37679.1 - 2.1e-20 73.2 0.0 3.2e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal AGH PF17558.2 GAM37679.1 - 0.13 12.5 0.2 0.31 11.2 0.2 1.6 1 0 0 1 1 1 0 Androgenic gland hormone DASH_Hsk3 PF08227.11 GAM37680.1 - 6.8e-22 77.6 0.7 1.2e-21 76.8 0.7 1.4 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like DUF5421 PF17458.2 GAM37680.1 - 0.014 14.8 0.6 0.014 14.8 0.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5421) BBS2_C PF14782.6 GAM37680.1 - 0.026 13.3 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal His_Phos_1 PF00300.22 GAM37681.1 - 5.3e-37 127.4 0.2 7.1e-19 68.3 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Amidohydro_3 PF07969.11 GAM37682.1 - 1.6e-46 159.8 1.7 2.1e-46 159.4 1.7 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 GAM37682.1 - 2e-16 60.2 0.3 7.8e-14 51.7 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Hydrolase_6 PF13344.6 GAM37682.1 - 0.033 14.3 0.2 3.1 8.0 0.0 3.1 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase SpoVS PF04232.12 GAM37682.1 - 0.17 11.6 0.1 6.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Stage V sporulation protein S (SpoVS) PHD PF00628.29 GAM37683.1 - 3.1e-06 27.0 9.0 5e-06 26.3 9.0 1.4 1 0 0 1 1 1 1 PHD-finger DivIC PF04977.15 GAM37683.1 - 0.0084 15.9 8.5 0.96 9.3 0.1 2.4 2 0 0 2 2 2 2 Septum formation initiator Fzo_mitofusin PF04799.13 GAM37683.1 - 0.019 14.5 4.3 0.11 12.0 0.6 2.1 2 0 0 2 2 2 0 fzo-like conserved region DUF1192 PF06698.11 GAM37683.1 - 0.038 14.0 0.9 0.038 14.0 0.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) ZapB PF06005.12 GAM37683.1 - 0.039 14.4 7.7 0.19 12.2 2.9 2.4 2 0 0 2 2 2 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 GAM37683.1 - 0.044 13.8 8.5 1.8 8.6 2.4 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SPX PF03105.19 GAM37683.1 - 0.05 13.5 14.0 0.058 13.3 7.7 2.1 2 0 0 2 2 2 0 SPX domain Zf_RING PF16744.5 GAM37683.1 - 0.052 13.7 10.3 0.24 11.5 9.6 2.1 1 1 0 1 1 1 0 KIAA1045 RING finger Rootletin PF15035.6 GAM37683.1 - 0.063 13.3 3.9 0.11 12.5 3.9 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion PHD_2 PF13831.6 GAM37683.1 - 0.083 12.5 4.2 0.16 11.6 4.2 1.5 1 0 0 1 1 1 0 PHD-finger C6_DPF PF10170.9 GAM37683.1 - 0.092 13.1 1.7 0.19 12.1 1.7 1.5 1 0 0 1 1 1 0 Cysteine-rich domain PI3K_P85_iSH2 PF16454.5 GAM37683.1 - 0.11 12.1 7.5 0.2 11.3 1.3 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4140 PF13600.6 GAM37683.1 - 0.14 12.6 3.1 6.9 7.2 0.9 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HAUS-augmin3 PF14932.6 GAM37683.1 - 0.21 11.1 2.5 1.7 8.1 0.7 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 zf-HC5HC2H PF13771.6 GAM37683.1 - 0.26 11.5 4.9 0.59 10.4 4.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Fez1 PF06818.15 GAM37683.1 - 0.3 11.5 6.8 0.95 9.9 6.9 1.7 1 1 0 1 1 1 0 Fez1 Shugoshin_N PF07558.11 GAM37683.1 - 0.35 10.8 3.2 0.19 11.7 0.9 1.7 2 0 0 2 2 1 0 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.21 GAM37683.1 - 0.43 10.7 6.5 9.2 6.5 2.7 2.4 2 0 0 2 2 2 0 bZIP transcription factor YabA PF06156.13 GAM37683.1 - 0.51 11.0 1.6 8.9 7.0 0.3 2.5 2 0 0 2 2 2 0 Initiation control protein YabA APC_N_CC PF16689.5 GAM37683.1 - 0.58 10.3 2.9 0.67 10.1 0.3 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain XRN_M PF17846.1 GAM37683.1 - 0.67 8.8 2.4 1 8.2 2.4 1.2 1 0 0 1 1 1 0 Xrn1 helical domain GAS PF13851.6 GAM37683.1 - 0.67 9.3 7.7 1.1 8.6 5.7 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TSC22 PF01166.18 GAM37683.1 - 0.91 9.9 3.1 1.2 9.5 0.2 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 GAM37683.1 - 1.1 9.3 8.5 6.4 6.8 3.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.12 GAM37683.1 - 1.3 9.0 9.1 0.099 12.5 1.5 2.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Uds1 PF15456.6 GAM37683.1 - 1.6 8.9 12.0 0.06 13.5 6.1 1.7 2 0 0 2 2 1 0 Up-regulated During Septation TPR_MLP1_2 PF07926.12 GAM37683.1 - 1.9 8.6 11.7 8.7 6.4 4.7 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein THOC7 PF05615.13 GAM37683.1 - 2.4 8.4 7.5 1.6 9.0 3.9 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 ADIP PF11559.8 GAM37683.1 - 2.6 8.1 7.4 2.9 8.0 0.3 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Swi5 PF07061.11 GAM37683.1 - 2.8 8.1 4.4 25 5.1 1.1 2.4 2 0 0 2 2 2 0 Swi5 Spc24 PF08286.11 GAM37683.1 - 8.1 6.7 6.4 9.9 6.5 1.9 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 C1_1 PF00130.22 GAM37683.1 - 8.8 6.3 11.9 0.49 10.3 5.7 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Macoilin PF09726.9 GAM37683.1 - 9.3 4.7 14.5 0.043 12.4 0.3 2.5 2 1 1 3 3 3 0 Macoilin family AdoMet_MTase PF07757.13 GAM37684.1 - 4.8e-35 120.3 0.1 2e-33 115.1 0.5 2.6 2 1 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase SMC_N PF02463.19 GAM37685.1 - 2.4e-19 69.7 10.0 8.2e-19 67.9 10.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAM37685.1 - 3.3e-14 53.9 23.5 3.3e-14 53.9 23.5 5.0 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAM37685.1 - 3.2e-07 30.5 8.7 0.0012 18.7 0.6 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAM37685.1 - 1.4e-05 25.0 7.3 1.4e-05 25.0 7.3 3.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 GAM37685.1 - 0.00029 20.5 0.0 0.00061 19.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NPV_P10 PF05531.12 GAM37685.1 - 0.0086 16.5 13.9 2.1 8.9 0.5 5.9 3 1 1 4 4 4 2 Nucleopolyhedrovirus P10 protein AAA_27 PF13514.6 GAM37685.1 - 0.011 15.4 0.0 0.011 15.4 0.0 4.0 6 0 0 6 6 6 0 AAA domain AAA_25 PF13481.6 GAM37685.1 - 0.05 13.2 0.9 0.6 9.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GAM37685.1 - 0.11 12.4 0.0 0.76 9.7 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AHSP PF09236.10 GAM37685.1 - 0.74 10.3 3.9 3.1 8.3 1.1 3.2 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein Ax_dynein_light PF10211.9 GAM37686.1 - 0.0098 15.9 1.4 0.011 15.7 1.4 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain DUF5305 PF17231.2 GAM37686.1 - 0.028 13.8 0.0 0.04 13.3 0.0 1.2 1 1 0 1 1 1 0 Family of unknown function (DUF5305) COX7a PF02238.15 GAM37686.1 - 0.039 14.3 0.5 0.083 13.3 0.5 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII CytB6-F_Fe-S PF08802.10 GAM37686.1 - 0.22 11.6 0.1 0.3 11.2 0.1 1.2 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit Lipase_3 PF01764.25 GAM37687.1 - 3.2e-18 66.0 0.0 3.9e-16 59.2 0.0 2.5 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 GAM37687.1 - 0.0016 19.1 0.5 0.038 14.6 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM37687.1 - 0.056 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FMN_dh PF01070.18 GAM37688.1 - 5.8e-120 400.5 0.0 6.6e-120 400.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 GAM37688.1 - 7.7e-06 25.4 0.1 0.056 12.8 0.2 3.2 4 0 0 4 4 4 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 GAM37688.1 - 3.1e-05 23.5 0.2 4.6e-05 23.0 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAM37688.1 - 0.00013 21.1 0.6 0.00022 20.4 0.6 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 GAM37688.1 - 0.00019 20.7 0.1 0.0003 20.0 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 GAM37688.1 - 0.0062 16.0 0.4 0.61 9.5 0.1 2.7 2 1 1 3 3 3 2 Histidine biosynthesis protein IGPS PF00218.21 GAM37688.1 - 0.034 13.3 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase PcrB PF01884.17 GAM37688.1 - 0.13 11.7 0.0 11 5.4 0.0 2.7 2 1 0 3 3 3 0 PcrB family His_Phos_2 PF00328.22 GAM37689.1 - 2e-31 109.7 0.0 7.5e-31 107.8 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Med13_C PF06333.12 GAM37690.1 - 0.33 10.2 2.9 0.23 10.7 1.2 1.5 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain NAC PF01849.18 GAM37691.1 - 4.5e-25 87.4 0.7 6.4e-25 86.9 0.7 1.2 1 0 0 1 1 1 1 NAC domain adh_short PF00106.25 GAM37692.1 - 1.5e-20 73.5 0.7 1.1e-15 57.6 0.1 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37692.1 - 2.5e-09 37.1 0.2 1.4e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM37692.1 - 9.2e-09 35.5 0.9 1.8e-08 34.5 0.1 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GAM37692.1 - 0.00097 18.4 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 GAM37692.1 - 0.0041 17.7 0.1 0.0097 16.5 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 GAM37692.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 GAM37692.1 - 0.078 12.4 0.1 2.8 7.3 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAM37692.1 - 0.13 12.3 0.1 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_2 PF02230.16 GAM37693.1 - 1.2e-61 208.3 0.0 1.4e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 GAM37693.1 - 1.6e-05 24.3 0.5 0.0051 16.1 0.0 3.0 2 1 1 3 3 3 1 Serine aminopeptidase, S33 FSH1 PF03959.13 GAM37693.1 - 9.7e-05 22.1 0.0 0.00023 20.9 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 GAM37693.1 - 0.00022 20.8 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAM37693.1 - 0.00048 19.7 0.0 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 GAM37693.1 - 0.00077 19.4 0.0 0.17 11.7 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2920 PF11144.8 GAM37693.1 - 0.0035 16.6 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2920) Abhydrolase_6 PF12697.7 GAM37693.1 - 0.0066 17.1 0.0 0.0087 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1581 PF07619.11 GAM37693.1 - 0.017 15.3 0.1 0.027 14.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) Abhydrolase_1 PF00561.20 GAM37693.1 - 0.025 14.2 0.2 18 4.9 0.0 3.0 2 1 1 3 3 3 0 alpha/beta hydrolase fold Ctr PF04145.15 GAM37695.1 - 8e-33 114.1 1.3 1e-32 113.8 1.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Papilloma_E5A PF05776.12 GAM37695.1 - 0.049 14.0 0.2 0.15 12.5 0.2 1.7 1 0 0 1 1 1 0 Papillomavirus E5A protein PAP2 PF01569.21 GAM37695.1 - 0.12 12.1 0.2 0.12 12.1 0.2 2.1 2 1 0 2 2 2 0 PAP2 superfamily DUF3446 PF11928.8 GAM37695.1 - 6.3 7.2 13.4 11 6.3 13.4 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain FAD_binding_8 PF08022.12 GAM37696.1 - 1e-20 73.9 0.0 2.5e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 GAM37696.1 - 1.6e-20 73.8 0.1 3.3e-20 72.8 0.1 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 GAM37696.1 - 3.2e-18 66.0 13.0 3.2e-18 66.0 13.0 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 GAM37696.1 - 0.056 14.1 0.1 8.4 7.1 0.0 2.6 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAM37696.1 - 0.065 13.6 0.0 0.2 12.0 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain HET PF06985.11 GAM37697.1 - 1.3e-07 32.1 0.2 0.0005 20.5 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Aminotran_5 PF00266.19 GAM37698.1 - 3.6e-51 174.2 0.2 2.3e-44 151.9 0.1 1.9 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 GAM37698.1 - 3.9e-07 29.6 0.1 7.1e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAM37698.1 - 0.0003 19.4 0.1 0.00065 18.3 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Robl_LC7 PF03259.17 GAM37699.1 - 0.0078 16.0 0.1 1.4 8.7 0.0 3.0 3 0 0 3 3 3 2 Roadblock/LC7 domain Myc_N PF01056.18 GAM37699.1 - 0.019 14.9 0.2 0.019 14.9 0.2 2.2 1 1 0 2 2 2 0 Myc amino-terminal region DLH PF01738.18 GAM37700.1 - 2.7e-10 40.2 0.3 4.3e-10 39.5 0.3 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family zf-C2H2_4 PF13894.6 GAM37701.1 - 4.4e-09 36.4 9.6 0.00041 20.9 0.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM37701.1 - 2.7e-08 33.8 11.2 3.9e-05 23.9 0.8 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM37701.1 - 6e-07 29.6 14.6 3e-05 24.2 3.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 GAM37701.1 - 0.0014 18.4 7.6 0.22 11.3 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 GAM37701.1 - 0.0042 17.3 4.1 0.084 13.2 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 GAM37701.1 - 0.0089 16.0 6.4 0.96 9.5 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 GAM37701.1 - 0.023 15.1 10.0 0.65 10.5 1.8 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 GAM37701.1 - 0.078 12.8 2.6 2.6 7.9 0.3 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 GAM37701.1 - 0.87 9.7 7.0 0.1 12.6 1.9 2.1 2 1 0 2 2 2 0 BED zinc finger zf-AN1 PF01428.16 GAM37701.1 - 5.6 7.2 9.1 25 5.1 2.1 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger Pyridoxal_deC PF00282.19 GAM37702.1 - 8.9e-62 209.0 0.0 1.4e-61 208.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Fungal_trans_2 PF11951.8 GAM37702.1 - 1.3e-58 198.7 0.7 2.7e-58 197.6 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM37702.1 - 1.7e-06 28.1 12.6 2.8e-06 27.4 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.19 GAM37702.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V EutQ PF06249.12 GAM37704.1 - 2.9e-12 46.6 0.0 3.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 GAM37704.1 - 6.3e-10 38.6 0.0 8.3e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 GAM37704.1 - 1.9e-06 27.5 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Pirin PF02678.16 GAM37704.1 - 0.0096 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Pirin KduI PF04962.12 GAM37704.1 - 0.027 13.8 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family Cupin_1 PF00190.22 GAM37704.1 - 0.052 13.1 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Cupin cNMP_binding PF00027.29 GAM37704.1 - 0.073 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Cupin_6 PF12852.7 GAM37704.1 - 0.21 11.3 0.0 0.32 10.7 0.0 1.3 1 1 0 1 1 1 0 Cupin Pkinase PF00069.25 GAM37705.1 - 7.8e-60 202.5 0.0 5e-59 199.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM37705.1 - 3.6e-28 98.6 0.2 1.5e-19 70.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GAM37705.1 - 1.2e-05 25.3 3.8 0.16 11.9 0.1 3.7 3 1 1 4 4 4 3 Phosphotransferase enzyme family Pkinase_C PF00433.24 GAM37705.1 - 0.0006 20.5 0.6 0.0018 19.0 0.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 GAM37705.1 - 0.0029 17.0 0.1 0.013 14.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAM37705.1 - 0.013 14.5 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF1687 PF07955.11 GAM37706.1 - 7.1e-26 91.2 0.0 2.1e-25 89.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.15 GAM37706.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 ArsC family Ipi1_N PF12333.8 GAM37707.1 - 4.7e-28 97.8 1.2 3e-27 95.2 0.0 2.6 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.22 GAM37707.1 - 0.0081 16.3 1.4 11 6.6 0.1 3.7 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 GAM37707.1 - 0.01 16.2 0.1 0.032 14.6 0.1 1.8 1 0 0 1 1 1 0 HEAT repeats HEAT_EZ PF13513.6 GAM37707.1 - 0.038 14.5 4.0 0.4 11.3 0.3 3.6 2 1 2 4 4 4 0 HEAT-like repeat DAO PF01266.24 GAM37709.1 - 2.4e-31 109.6 0.9 3.6e-30 105.7 0.9 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 GAM37709.1 - 0.00078 19.7 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_8 PF13450.6 GAM37709.1 - 0.0035 17.5 0.1 0.0077 16.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAM37709.1 - 0.01 14.7 1.2 0.29 9.9 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DUF2283 PF10049.9 GAM37709.1 - 0.019 15.2 0.3 0.039 14.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) Pyr_redox_2 PF07992.14 GAM37709.1 - 0.022 14.0 2.1 0.82 8.8 2.1 2.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.23 GAM37709.1 - 0.057 13.5 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAM37709.1 - 0.062 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 GAM37709.1 - 0.068 12.8 0.2 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 GAM37709.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 ThiF family GATA PF00320.27 GAM37710.1 - 1.7e-16 59.5 2.3 3.1e-16 58.7 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 GAM37710.1 - 1.6e-12 47.0 2.6 3.1e-12 46.1 2.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AreA_N PF07573.11 GAM37710.1 - 0.0045 17.6 0.2 0.0045 17.6 0.2 3.4 2 0 0 2 2 2 1 Nitrogen regulatory protein AreA N terminus Serglycin PF04360.12 GAM37711.1 - 0.087 12.8 0.0 0.098 12.6 0.0 1.1 1 0 0 1 1 1 0 Serglycin Gly-zipper_YMGG PF13441.6 GAM37711.1 - 0.12 12.1 11.2 0.15 11.8 11.2 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Pyrid_oxidase_2 PF13883.6 GAM37712.1 - 4.7e-36 124.3 0.0 7.2e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cyclin PF08613.11 GAM37713.1 - 3.9e-07 30.6 1.2 1.5e-06 28.6 0.0 2.4 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 GAM37713.1 - 0.00026 20.7 0.0 0.00058 19.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain RdRP PF05183.12 GAM37714.1 - 7.1e-181 602.8 0.0 9.1e-181 602.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase ADH_N PF08240.12 GAM37715.1 - 5e-29 100.4 4.3 6.2e-29 100.1 2.8 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM37715.1 - 3.7e-21 75.5 0.0 6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAM37715.1 - 1.7e-11 44.1 0.0 2.9e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAM37715.1 - 1.5e-05 26.1 0.0 2.7e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAM37715.1 - 0.0003 20.1 0.1 0.00049 19.5 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 GAM37715.1 - 0.0018 17.6 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 GAM37715.1 - 0.027 13.8 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 GAM37715.1 - 0.03 14.6 0.0 0.071 13.4 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 GAM37715.1 - 0.047 13.3 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 GAM37715.1 - 0.06 12.0 0.1 0.09 11.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 GAM37715.1 - 0.096 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 GAM37715.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 GAM37715.1 - 0.15 11.1 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain AdoHcyase_NAD PF00670.21 GAM37715.1 - 0.15 12.1 0.3 0.4 10.7 0.1 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fungal_trans PF04082.18 GAM37716.1 - 8e-21 74.2 0.1 2.2e-20 72.8 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain RVT_1 PF00078.27 GAM37718.1 - 6.6e-39 133.7 0.0 1.1e-38 133.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 GAM37718.1 - 1.7e-12 47.2 0.1 4e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 GAM37718.1 - 0.0045 16.5 0.1 0.009 15.5 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UvrD_C_2 PF13538.6 GAM37718.1 - 0.14 12.0 0.5 14 5.6 0.1 2.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain ADH_N PF08240.12 GAM37719.1 - 7.4e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM37719.1 - 0.051 13.5 0.2 0.18 11.8 0.1 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase adh_short PF00106.25 GAM37720.1 - 2e-28 99.2 1.0 1.2e-26 93.4 1.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37720.1 - 1.6e-15 57.3 0.2 1.1e-14 54.6 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM37720.1 - 4.6e-06 26.7 0.1 1.2e-05 25.3 0.1 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GAM37720.1 - 0.028 13.5 0.2 0.053 12.6 0.1 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Lectin_legB PF00139.19 GAM37720.1 - 0.078 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Legume lectin domain BTB_2 PF02214.22 GAM37724.1 - 6.6e-05 23.2 0.0 0.00017 21.9 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain RecC_C PF17946.1 GAM37724.1 - 0.21 11.4 0.1 0.29 10.9 0.1 1.2 1 0 0 1 1 1 0 RecC C-terminal domain p450 PF00067.22 GAM37725.1 - 1.3e-22 80.2 0.0 1.7e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.25 GAM37727.1 - 4.2e-08 33.4 0.1 2.1e-07 31.2 0.1 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM37727.1 - 1.5e-05 24.9 0.0 0.015 15.2 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM37727.1 - 7e-05 23.2 0.0 0.00026 21.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF676 PF05057.14 GAM37727.1 - 0.00025 20.6 0.1 0.0012 18.4 0.1 1.9 1 1 1 2 2 2 1 Putative serine esterase (DUF676) NB-ARC PF00931.22 GAM37727.1 - 0.032 13.4 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 GAM37727.1 - 0.044 13.7 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Hydrolase_4 PF12146.8 GAM37727.1 - 0.078 12.2 0.0 0.2 10.9 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM37727.1 - 0.094 13.3 0.2 0.41 11.2 0.0 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family AAA_16 PF13191.6 GAM37727.1 - 0.1 12.9 1.1 0.59 10.5 1.1 2.5 1 1 0 1 1 1 0 AAA ATPase domain HTH_Tnp_Tc5 PF03221.16 GAM37728.1 - 1.3e-06 28.3 0.0 5.6e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 GAM37728.1 - 0.044 13.5 0.2 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 helix-turn-helix, Psq domain adh_short PF00106.25 GAM37731.1 - 6.1e-36 123.7 0.0 9.9e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37731.1 - 3.7e-20 72.5 0.0 6.1e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM37731.1 - 3.6e-05 23.7 0.0 7.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.8 GAM37731.1 - 7.9e-05 21.6 0.9 0.00058 18.8 0.4 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Epimerase PF01370.21 GAM37731.1 - 0.0014 18.1 1.0 0.0086 15.6 1.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM37731.1 - 0.0059 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 GAM37731.1 - 0.026 14.6 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAM37731.1 - 0.04 14.2 0.1 0.086 13.1 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Zn_clus PF00172.18 GAM37731.1 - 0.11 12.6 1.1 0.22 11.6 1.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1776 PF08643.10 GAM37731.1 - 0.15 11.4 0.0 0.52 9.6 0.0 1.9 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) adh_short PF00106.25 GAM37732.1 - 1.6e-25 89.7 0.0 1.5e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37732.1 - 6e-12 45.6 0.0 0.00011 21.8 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM37732.1 - 1.7e-07 31.3 0.4 0.0002 21.3 0.1 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 GAM37732.1 - 0.0063 16.0 0.0 0.025 14.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM37732.1 - 0.0087 16.0 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAM37732.1 - 0.013 15.7 0.0 0.026 14.8 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 GAM37733.1 - 0.0002 21.3 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM37733.1 - 0.00039 21.5 0.0 0.00048 21.2 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase rve_3 PF13683.6 GAM37734.1 - 0.0013 18.5 2.9 0.0048 16.7 0.5 2.4 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 GAM37734.1 - 0.01 15.5 2.6 0.013 15.2 0.9 2.1 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type BK_channel_a PF03493.18 GAM37734.1 - 0.022 14.9 0.1 0.045 13.9 0.1 1.6 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit RA PF00788.23 GAM37734.1 - 0.046 14.4 0.0 0.098 13.3 0.0 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Sporozoite_P67 PF05642.11 GAM37734.1 - 0.14 10.2 0.3 0.17 9.9 0.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Methyltransf_11 PF08241.12 GAM37735.1 - 3.3e-06 27.6 0.0 4.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM37735.1 - 0.00024 21.8 0.0 0.00039 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM37735.1 - 0.00032 20.6 0.0 0.00045 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM37735.1 - 0.0084 15.5 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 GAM37735.1 - 0.023 15.4 0.0 0.043 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Spo7_2_N PF15407.6 GAM37735.1 - 0.031 13.9 0.1 0.48 10.1 0.0 2.5 1 1 1 2 2 2 0 Sporulation protein family 7 DRE2_N PF16803.5 GAM37735.1 - 0.095 12.9 0.0 0.18 12.0 0.0 1.5 1 1 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Amidohydro_2 PF04909.14 GAM37736.1 - 6.6e-34 118.0 0.0 9.3e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase p450 PF00067.22 GAM37737.1 - 1.9e-73 247.8 0.0 2.5e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2841 PF11001.8 GAM37737.1 - 3.1e-26 91.9 0.1 6.5e-26 90.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) ADH_N PF08240.12 GAM37737.1 - 2.9e-21 75.4 0.1 5.3e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM37737.1 - 2.1e-12 47.2 0.0 4.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.25 GAM37738.1 - 0.0003 20.2 0.2 0.00035 20.0 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Fungal_trans PF04082.18 GAM37739.1 - 1.3e-12 47.3 0.0 3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Folate_carrier PF01770.18 GAM37739.1 - 0.066 11.9 0.5 0.11 11.3 0.5 1.2 1 0 0 1 1 1 0 Reduced folate carrier Methyltransf_31 PF13847.6 GAM37740.1 - 9.3e-28 96.9 0.0 1.3e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM37740.1 - 1.3e-22 80.3 0.0 2e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM37740.1 - 1.3e-22 80.3 0.0 2.1e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM37740.1 - 9.6e-18 64.4 0.0 1.5e-17 63.7 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAM37740.1 - 2e-14 53.8 0.0 2.9e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM37740.1 - 7.6e-13 49.0 0.0 1.4e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 GAM37740.1 - 3.6e-09 36.5 0.0 5.2e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 GAM37740.1 - 1.6e-06 28.1 0.0 2.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 GAM37740.1 - 7.5e-06 25.6 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 GAM37740.1 - 8.2e-06 25.4 0.1 1.5e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.7 GAM37740.1 - 1.1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 GAM37740.1 - 9.7e-05 21.4 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 GAM37740.1 - 0.00011 21.9 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 GAM37740.1 - 0.0032 16.8 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 GAM37740.1 - 0.0039 15.8 0.0 0.0048 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 GAM37740.1 - 0.008 15.3 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.6 GAM37740.1 - 0.04 15.0 0.0 0.081 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 GAM37740.1 - 0.064 12.8 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TehB PF03848.14 GAM37740.1 - 0.066 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.19 GAM37740.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase GCD14 PF08704.10 GAM37740.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_32 PF13679.6 GAM37740.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Sua5_yciO_yrdC PF01300.18 GAM37741.1 - 8.5e-08 31.9 0.0 1.1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination MFS_1 PF07690.16 GAM37742.1 - 1.3e-35 123.0 28.3 1.3e-35 123.0 28.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAM37742.1 - 9e-05 20.9 2.3 9e-05 20.9 2.3 2.3 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 GAM37743.1 - 1.4e-07 31.5 14.0 2.7e-07 30.6 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 GAM37744.1 - 2.1e-21 76.6 0.0 2.2e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM37744.1 - 1.3e-07 31.3 0.1 1.7e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase GMC_oxred_N PF00732.19 GAM37745.1 - 5.7e-54 183.5 0.0 8.3e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM37745.1 - 9e-34 117.1 0.0 1.5e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GIDA PF01134.22 GAM37745.1 - 2.8e-06 26.7 0.0 0.038 13.1 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GAM37745.1 - 3.5e-06 26.3 0.0 5.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAM37745.1 - 2e-05 23.9 0.0 0.00046 19.4 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM37745.1 - 2.7e-05 23.6 0.0 0.00073 18.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM37745.1 - 5.5e-05 22.0 0.0 0.0065 15.2 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 GAM37745.1 - 0.00016 21.9 0.1 0.00047 20.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM37745.1 - 0.00025 20.7 0.0 0.0015 18.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAM37745.1 - 0.001 18.4 0.0 0.45 9.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM37745.1 - 0.047 12.9 0.1 0.092 12.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HPP PF04982.13 GAM37746.1 - 4.9e-41 139.7 7.8 7.8e-41 139.1 6.0 1.9 2 0 0 2 2 2 1 HPP family DUF4131 PF13567.6 GAM37746.1 - 3.6 7.2 11.3 5.5 6.6 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) CN_hydrolase PF00795.22 GAM37747.1 - 9.1e-37 126.8 0.0 1.1e-36 126.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PhyH PF05721.13 GAM37748.1 - 6.5e-14 52.7 0.1 8.3e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) APH PF01636.23 GAM37749.1 - 1.2e-14 54.8 0.0 1.7e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM37749.1 - 6.7e-05 22.6 0.0 9.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 GAM37749.1 - 0.0031 16.9 0.0 0.48 9.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 GAM37749.1 - 0.037 13.6 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.20 GAM37749.1 - 0.042 13.1 0.0 0.068 12.5 0.0 1.4 1 1 0 1 1 1 0 Ecdysteroid kinase ABC1 PF03109.16 GAM37749.1 - 0.047 13.9 0.1 0.15 12.2 0.0 1.8 1 1 1 2 2 2 0 ABC1 family Glyco_hydro_28 PF00295.17 GAM37750.1 - 2.2e-93 312.9 25.6 9.6e-52 176.0 4.9 2.8 3 0 0 3 3 3 2 Glycosyl hydrolases family 28 Pectinesterase PF01095.19 GAM37750.1 - 2.1e-42 144.9 1.4 5.7e-42 143.5 0.5 2.1 3 0 0 3 3 3 1 Pectinesterase TauD PF02668.16 GAM37751.1 - 6e-60 203.3 1.3 6e-60 203.3 0.3 1.4 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family Peptidase_S8 PF00082.22 GAM37752.1 - 1.3e-33 116.5 8.5 9.6e-33 113.7 7.9 2.2 2 0 0 2 2 2 1 Subtilase family Bac_luciferase PF00296.20 GAM37752.1 - 5.4e-24 85.2 0.3 1.4e-21 77.3 0.1 2.3 2 0 0 2 2 2 2 Luciferase-like monooxygenase fn3_5 PF06280.12 GAM37752.1 - 2.2e-17 63.8 0.0 5e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain RPT PF13446.6 GAM37752.1 - 0.04 13.8 0.1 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 A repeated domain in UCH-protein Pyr_redox_3 PF13738.6 GAM37753.1 - 2.6e-11 43.3 0.2 1.3e-09 37.8 0.4 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM37753.1 - 9.4e-11 41.8 0.0 4.3e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM37753.1 - 3.3e-10 39.7 0.0 3.4e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAM37753.1 - 8.8e-09 34.3 1.1 1.6e-06 26.8 0.3 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAM37753.1 - 1.2e-08 34.5 0.3 1.2e-06 27.9 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAM37753.1 - 2.1e-06 27.8 0.0 0.007 16.4 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 GAM37753.1 - 0.0016 17.7 0.1 0.0033 16.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 GAM37753.1 - 0.0085 15.7 0.1 4.2 6.9 0.0 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase Mqo PF06039.15 GAM37753.1 - 0.077 11.5 0.0 9.5 4.6 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_oxidored PF12831.7 GAM37753.1 - 0.18 11.1 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 GAM37753.1 - 0.22 10.6 0.3 6.2 5.8 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Ribonuc_L-PSP PF01042.21 GAM37754.1 - 1.6e-12 47.5 0.0 2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP AA_permease PF00324.21 GAM37755.1 - 2.6e-98 329.7 31.2 3.2e-98 329.4 31.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM37755.1 - 1.8e-30 106.2 33.7 2.1e-30 105.9 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_28 PF00295.17 GAM37756.1 - 6.9e-22 77.9 0.9 9.4e-22 77.5 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 GAM37756.1 - 0.00029 20.8 9.7 0.0014 18.5 9.7 2.3 1 1 0 1 1 1 1 Pectate lyase superfamily protein 2-Hacid_dh_C PF02826.19 GAM37757.1 - 1e-35 122.7 0.0 4e-34 117.5 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GAM37757.1 - 0.045 14.3 0.0 0.072 13.7 0.0 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 GAM37757.1 - 0.18 11.7 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fringe PF02434.16 GAM37758.1 - 1.2e-06 28.2 1.1 1.8e-05 24.4 1.1 2.3 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 GAM37758.1 - 0.002 18.0 2.4 0.0043 16.9 2.4 1.4 1 0 0 1 1 1 1 PAN domain DUF604 PF04646.12 GAM37758.1 - 0.0025 17.2 0.1 0.0045 16.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Atrophin-1 PF03154.15 GAM37758.1 - 0.026 12.9 1.3 0.039 12.3 1.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family TFIIE_beta PF02186.15 GAM37758.1 - 0.099 12.9 1.1 0.19 12.0 0.2 1.9 2 0 0 2 2 2 0 TFIIE beta subunit core domain Glyco_trans_2_3 PF13632.6 GAM37759.1 - 5.8e-10 39.4 2.3 1.1e-09 38.5 2.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.15 GAM37759.1 - 3.4e-07 29.3 4.2 1.9e-05 23.5 1.1 3.0 2 1 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 GAM37759.1 - 6.3e-07 29.5 0.2 1.3e-06 28.5 0.1 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GAM37759.1 - 8.7e-06 25.3 0.2 6.8e-05 22.4 0.2 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 MRP-S33 PF08293.11 GAM37760.1 - 0.035 14.3 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 Amidase PF01425.21 GAM37762.1 - 9.1e-99 331.4 0.0 1.4e-98 330.8 0.0 1.3 1 0 0 1 1 1 1 Amidase Pribosyltran_N PF13793.6 GAM37762.1 - 1.7e-40 137.5 0.0 4.3e-40 136.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAM37762.1 - 1.9e-15 57.4 0.6 4.3e-10 39.9 0.3 2.6 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAM37762.1 - 1.3e-12 47.6 0.1 3.3e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Glyco_hydro_76 PF03663.14 GAM37763.1 - 1.7e-45 156.1 13.2 1.7e-45 156.1 13.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 GAM37763.1 - 0.00063 18.9 2.7 0.19 10.8 0.0 3.3 2 1 1 4 4 4 3 Glycosyl Hydrolase Family 88 COesterase PF00135.28 GAM37764.1 - 2.9e-40 138.6 0.0 4.1e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM37764.1 - 8.1e-05 22.6 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.10 GAM37764.1 - 0.17 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Spherulin4 PF12138.8 GAM37765.1 - 2.5e-53 181.2 6.9 2.9e-53 181.0 6.9 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 AA_permease PF00324.21 GAM37766.1 - 3e-137 458.1 37.0 3.7e-137 457.8 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM37766.1 - 8.3e-38 130.3 40.6 1.1e-37 130.0 40.6 1.0 1 0 0 1 1 1 1 Amino acid permease tRNA-synt_2c PF01411.19 GAM37767.1 - 4.2e-08 32.2 0.2 1.2e-07 30.7 0.2 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 GAM37767.1 - 4.2e-06 26.7 0.4 8.3e-06 25.8 0.4 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Acetyltransf_1 PF00583.25 GAM37768.1 - 2.2e-14 53.7 0.0 2.8e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM37768.1 - 6.8e-09 36.0 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM37768.1 - 1.8e-08 34.4 0.0 2.4e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM37768.1 - 0.001 19.0 0.0 0.0019 18.1 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 GAM37768.1 - 0.0022 18.1 0.0 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 GAM37768.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.23 GAM37769.1 - 8.1e-32 109.9 7.3 1.3e-31 109.2 7.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM37769.1 - 3.2e-08 33.6 1.0 8.9e-08 32.1 1.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like NAD_Gly3P_dh_N PF01210.23 GAM37769.1 - 0.055 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Cu-oxidase_2 PF07731.14 GAM37770.1 - 7.6e-39 132.6 6.3 6.9e-36 123.0 0.1 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAM37770.1 - 4.4e-38 129.9 2.2 4.4e-38 129.9 2.2 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 GAM37770.1 - 4.9e-36 124.2 0.7 4.6e-34 117.8 0.5 2.4 2 0 0 2 2 2 2 Multicopper oxidase Glyco_hydro_76 PF03663.14 GAM37771.1 - 6.8e-103 345.0 22.2 8.3e-103 344.7 22.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MFS_1 PF07690.16 GAM37771.1 - 1.2e-18 67.1 13.3 2.1e-18 66.4 13.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM37771.1 - 0.00058 18.8 9.5 0.00098 18.1 9.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Mpv17_PMP22 PF04117.12 GAM37771.1 - 0.0035 17.5 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family OATP PF03137.20 GAM37771.1 - 0.017 13.4 0.5 0.017 13.4 0.5 1.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.19 GAM37772.1 - 2.8e-16 59.7 0.0 4.2e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_76 PF03663.14 GAM37772.1 - 9.5e-16 58.3 0.1 1.3e-15 57.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 LRR_5 PF13306.6 GAM37773.1 - 0.0024 17.8 0.2 0.091 12.7 0.0 2.6 1 1 2 3 3 3 1 BspA type Leucine rich repeat region (6 copies) DsbC_N PF10411.9 GAM37773.1 - 0.12 11.8 0.0 0.37 10.3 0.0 1.9 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus GMC_oxred_C PF05199.13 GAM37774.1 - 1.4e-33 116.4 0.0 2.4e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 GAM37774.1 - 7.8e-21 74.7 0.1 1.2e-20 74.1 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.16 GAM37774.1 - 2e-09 36.8 26.5 2e-09 36.8 26.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAM37774.1 - 1.3e-06 28.2 2.1 1.3e-06 28.2 2.1 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 GAM37774.1 - 0.67 8.7 14.6 0.074 11.9 7.4 2.2 2 0 0 2 2 2 0 Sugar (and other) transporter Sugar_tr PF00083.24 GAM37775.1 - 6e-95 318.8 33.1 7.4e-95 318.4 33.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37775.1 - 3.1e-22 79.0 30.4 3.1e-22 79.0 30.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily YlaC PF10777.9 GAM37775.1 - 8.7 6.2 9.8 0.9 9.4 4.5 2.1 2 0 0 2 2 2 0 Inner membrane protein YlaC GST_N_3 PF13417.6 GAM37776.1 - 7.6e-11 42.3 0.0 2.2e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM37776.1 - 7.5e-09 35.8 0.0 1.4e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM37776.1 - 0.0053 16.8 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM37776.1 - 0.0057 16.8 0.0 0.0091 16.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM37776.1 - 0.099 13.0 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ADH_N PF08240.12 GAM37777.1 - 1.6e-26 92.3 0.4 3e-26 91.4 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM37777.1 - 6.5e-24 84.4 0.1 1.1e-23 83.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAM37777.1 - 0.0034 16.9 0.5 0.011 15.2 0.5 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 GAM37777.1 - 0.0097 15.3 0.1 0.025 13.9 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 GAM37777.1 - 0.031 14.8 0.1 0.063 13.8 0.1 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 GAM37777.1 - 0.036 13.4 0.4 0.066 12.5 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.12 GAM37778.1 - 7.4e-33 112.7 0.1 1.4e-32 111.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM37778.1 - 1.1e-10 41.6 0.3 2.4e-10 40.5 0.3 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAM37778.1 - 1.9e-08 34.1 0.2 0.0012 18.3 0.1 2.4 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 GAM37778.1 - 8.3e-05 22.0 0.0 0.00022 20.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM37778.1 - 0.0027 18.2 0.1 0.026 15.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 GAM37778.1 - 0.014 14.8 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 GAM37778.1 - 0.021 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAM37778.1 - 0.03 13.6 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 GAM37778.1 - 0.034 14.2 0.2 0.062 13.4 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAM37778.1 - 0.044 14.0 0.1 0.07 13.4 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAM37778.1 - 0.045 13.8 0.1 0.13 12.3 0.1 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 GAM37778.1 - 0.065 13.1 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 GAM37778.1 - 0.085 12.1 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 GAM37778.1 - 0.1 11.9 0.3 0.22 10.8 0.3 1.5 1 0 0 1 1 1 0 ThiF family NAD_binding_8 PF13450.6 GAM37778.1 - 0.15 12.3 0.6 0.4 10.9 0.6 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 GAM37778.1 - 0.16 11.6 0.1 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Transketolase_N PF00456.21 GAM37779.1 - 5e-100 334.7 0.0 7.3e-100 334.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAM37779.1 - 8.8e-28 97.2 0.2 3.6e-16 59.3 0.0 2.5 1 1 1 2 2 2 2 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAM37779.1 - 4.5e-09 36.2 0.0 1.7e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAM37779.1 - 1.5e-06 27.6 0.0 0.00065 19.0 0.1 2.4 2 0 0 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 GAM37779.1 - 1.8e-05 24.5 0.2 0.00012 21.9 0.2 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 GAM37779.1 - 0.039 12.9 0.4 0.12 11.3 0.1 2.0 2 1 0 2 2 2 0 Dehydrogenase E1 component adh_short_C2 PF13561.6 GAM37780.1 - 1.1e-47 162.6 0.1 3.5e-47 160.9 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM37780.1 - 9e-39 133.0 0.1 5.3e-38 130.4 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM37780.1 - 1.3e-13 51.2 0.3 2.9e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 KR domain Pyr_redox_3 PF13738.6 GAM37780.1 - 8.6e-11 41.6 0.1 1.8e-08 34.0 0.0 3.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM37780.1 - 9.5e-11 41.5 0.0 3.5e-07 29.7 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAM37780.1 - 2.8e-09 36.0 0.0 6.4e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAM37780.1 - 6.2e-08 32.2 0.1 4.8e-06 26.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAM37780.1 - 2.2e-07 31.0 0.0 1.3e-06 28.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM37780.1 - 0.0061 16.2 2.8 1.3 8.5 0.0 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM37780.1 - 0.012 15.7 0.4 2.5 8.1 0.0 3.9 4 0 0 4 4 4 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 GAM37780.1 - 0.013 14.8 0.1 10 5.4 0.0 3.1 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 GAM37780.1 - 0.024 13.7 1.4 0.21 10.6 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 GAM37780.1 - 0.14 12.2 0.0 2 8.4 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 GAM37781.1 - 2.6e-44 151.5 0.5 2.3e-42 145.2 0.0 2.6 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM37781.1 - 4.4e-30 104.6 0.4 6e-27 94.4 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 GAM37781.1 - 1.7e-15 57.1 0.2 4e-15 55.9 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM37781.1 - 7.3e-10 38.3 0.0 1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAM37781.1 - 3.3e-08 33.7 0.0 5.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAM37781.1 - 3.3e-06 26.7 0.0 5.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAM37781.1 - 4.2e-05 22.8 0.4 0.00026 20.2 0.3 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAM37781.1 - 0.00069 18.8 0.6 0.0031 16.7 0.6 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAM37781.1 - 0.00071 19.5 1.0 0.18 11.7 0.5 3.1 2 1 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.24 GAM37781.1 - 0.0014 19.0 0.0 0.0029 18.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAM37781.1 - 0.0058 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 GAM37781.1 - 0.0086 15.6 0.1 0.023 14.2 0.1 1.8 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 GAM37781.1 - 0.13 12.5 0.1 0.78 10.0 0.0 2.2 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain DFP PF04127.15 GAM37781.1 - 0.13 12.0 0.6 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein PGM_PMM_II PF02879.16 GAM37781.1 - 0.14 12.7 0.1 0.52 11.0 0.0 1.9 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Glyco_hydro_88 PF07470.13 GAM37783.1 - 2.3e-70 237.4 5.4 2.9e-70 237.0 5.4 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Myb_DNA-binding PF00249.31 GAM37784.1 - 1.6e-25 89.0 1.8 2.1e-14 53.4 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM37784.1 - 2.5e-18 66.1 3.9 1.1e-14 54.4 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.8 GAM37784.1 - 0.011 15.9 0.0 0.042 14.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) SLIDE PF09111.10 GAM37784.1 - 0.03 14.3 0.0 0.095 12.7 0.0 1.8 1 1 1 2 2 2 0 SLIDE NCBP3 PF10309.9 GAM37785.1 - 3.4e-22 78.1 0.1 6.3e-22 77.2 0.1 1.5 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 ATP-synt_DE_N PF02823.16 GAM37787.1 - 4.6e-17 61.7 0.1 7.3e-17 61.1 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Phos_pyr_kin PF08543.12 GAM37788.1 - 2.7e-11 43.3 0.0 4.7e-11 42.5 0.0 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 GAM37788.1 - 4.2e-06 26.3 0.3 1.8e-05 24.2 0.3 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Mago-bind PF09282.10 GAM37788.1 - 0.17 11.8 0.2 0.36 10.7 0.2 1.5 1 0 0 1 1 1 0 Mago binding dUTPase PF00692.19 GAM37789.1 - 7.4e-44 148.5 0.0 9.5e-44 148.2 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 GAM37789.1 - 0.024 13.4 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) APH PF01636.23 GAM37790.1 - 4.1e-46 157.8 0.0 6.7e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM37790.1 - 2.7e-08 33.6 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 GAM37790.1 - 0.0001 22.0 0.0 0.0008 19.0 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 GAM37790.1 - 0.0004 19.8 0.0 0.0014 18.0 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 GAM37790.1 - 0.0013 18.1 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain EcKinase PF02958.20 GAM37790.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 GAM37790.1 - 0.0017 17.3 0.0 0.013 14.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) zf-C2H2 PF00096.26 GAM37791.1 - 1.1e-06 28.7 12.7 0.0094 16.4 2.6 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM37791.1 - 0.00079 19.7 10.6 0.83 10.2 0.2 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.12 GAM37791.1 - 0.0012 19.0 6.3 0.22 11.8 1.1 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 GAM37791.1 - 0.013 16.3 11.3 0.18 12.8 2.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM37792.1 - 1.5e-07 31.5 8.1 0.0022 18.4 0.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM37792.1 - 0.00043 20.9 12.7 0.16 12.9 0.1 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 GAM37792.1 - 0.001 19.7 4.0 0.24 12.0 0.0 2.9 1 1 2 3 3 3 2 FOXP coiled-coil domain CxC6 PF18721.1 GAM37792.1 - 2.3 8.5 6.4 1.8 8.9 3.7 2.1 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases zf-H2C2_5 PF13909.6 GAM37792.1 - 2.7 7.8 7.5 3.4 7.5 0.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain PQ-loop PF04193.14 GAM37793.1 - 9.4e-34 115.0 5.5 2.5e-17 62.4 0.0 2.7 2 0 0 2 2 2 2 PQ loop repeat Cytochrom_B561 PF03188.16 GAM37794.1 - 1.1e-07 32.1 8.1 1.1e-07 32.1 8.1 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF3824 PF12868.7 GAM37794.1 - 0.26 11.9 67.8 0.093 13.4 0.7 6.3 4 2 2 6 6 6 0 Domain of unknwon function (DUF3824) DUF202 PF02656.15 GAM37794.1 - 1.8 9.1 0.0 1.8 9.1 0.0 4.5 6 1 0 6 6 6 0 Domain of unknown function (DUF202) Gram_pos_anchor PF00746.21 GAM37794.1 - 2.3 8.2 9.6 25 4.9 0.2 4.5 4 0 0 4 4 4 0 LPXTG cell wall anchor motif Fungal_trans PF04082.18 GAM37795.1 - 3.9e-17 62.2 0.3 9e-17 61.0 0.3 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.18 GAM37796.1 - 2e-60 204.2 0.0 2.2e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Sulfatase PF00884.23 GAM37797.1 - 2.2e-70 237.5 0.0 2.7e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 GAM37797.1 - 0.0029 17.3 0.0 0.26 10.9 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 GAM37797.1 - 0.017 13.8 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 GAM37797.1 - 0.15 11.4 0.0 2.3 7.5 0.0 2.4 3 0 0 3 3 3 0 Metalloenzyme superfamily DUF2614 PF11023.8 GAM37798.1 - 0.0075 16.3 0.4 0.015 15.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon containing domain MFS_1 PF07690.16 GAM37799.1 - 5.7e-23 81.4 39.9 5.4e-21 74.9 34.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0542 PF15086.6 GAM37799.1 - 0.094 12.7 0.4 0.68 9.9 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 Glyco_hydro_3_C PF01915.22 GAM37800.1 - 3.2e-56 190.5 0.0 4.6e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAM37800.1 - 1.7e-39 136.0 0.0 3.5e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM37800.1 - 1.1e-15 57.5 0.0 3.3e-15 56.0 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 GAM37800.1 - 8.2e-05 22.4 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 PA14 domain COesterase PF00135.28 GAM37801.1 - 1e-72 245.7 0.0 1.7e-72 244.9 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM37801.1 - 6e-08 32.8 0.0 1.1e-06 28.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyoxalase PF00903.25 GAM37802.1 - 2.3e-06 27.8 0.0 7e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAM124 PF15067.6 GAM37802.1 - 0.16 11.6 0.1 0.49 10.0 0.1 1.8 1 1 0 1 1 1 0 FAM124 family Pyr_redox_2 PF07992.14 GAM37803.1 - 5.3e-33 114.5 0.0 6.9e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM37803.1 - 4.6e-11 43.1 0.2 2.6e-08 34.3 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM37803.1 - 3.1e-05 23.3 0.1 6.9e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAM37803.1 - 5.1e-05 22.7 0.0 8.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM37803.1 - 0.00021 21.0 0.4 2 7.9 0.7 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAM37803.1 - 0.0031 16.6 0.7 2.8 6.9 0.0 3.1 2 1 1 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.14 GAM37803.1 - 0.0076 15.1 0.4 0.78 8.5 0.0 2.6 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_9 PF13454.6 GAM37803.1 - 0.031 14.3 1.3 27 4.7 0.0 3.9 4 0 0 4 4 4 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 GAM37803.1 - 0.15 12.3 0.0 8.1 6.7 0.4 2.6 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Afi1 PF07792.12 GAM37804.1 - 6.3e-48 162.6 1.5 1.2e-47 161.8 1.5 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 GAM37804.1 - 6.5e-38 129.2 0.0 1e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 GAM37804.1 - 7.4e-09 34.8 0.0 0.0033 16.2 0.0 3.5 3 1 1 4 4 4 3 Transport protein Avl9 DUF1168 PF06658.12 GAM37804.1 - 0.07 12.9 7.3 0.15 11.8 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) CSRNP_N PF16019.5 GAM37804.1 - 0.12 12.2 1.1 0.22 11.4 1.1 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF2347 PF09804.9 GAM37804.1 - 0.16 11.5 0.0 0.53 9.8 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Nucleo_P87 PF07267.11 GAM37804.1 - 0.66 8.8 3.3 0.99 8.2 3.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 EF-hand_6 PF13405.6 GAM37805.1 - 1.4e-12 46.5 2.1 4.6e-05 23.0 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 GAM37805.1 - 1.9e-10 39.5 2.2 0.00018 20.8 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAM37805.1 - 6.7e-09 36.1 0.3 0.0021 18.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAM37805.1 - 2.9e-06 26.5 5.0 0.0083 15.6 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 GAM37805.1 - 5.4e-05 23.4 0.0 0.16 12.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GAM37805.1 - 7.9e-05 22.4 0.7 0.4 10.6 0.0 2.6 2 1 1 3 3 3 3 EF-hand domain pair PHO4 PF01384.20 GAM37806.1 - 3.1e-101 338.8 20.5 3.5e-101 338.6 20.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 GAM37806.1 - 5.3 7.4 10.5 1.3 9.4 0.6 2.9 2 1 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 RabGAP-TBC PF00566.18 GAM37807.1 - 3.3e-28 98.8 0.0 1.7e-23 83.5 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain WD40 PF00400.32 GAM37808.1 - 1.2e-18 67.1 9.1 5.6e-05 23.8 0.1 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat SET PF00856.28 GAM37808.1 - 2.4e-07 31.3 0.0 6.1e-06 26.7 0.0 3.4 3 1 0 3 3 3 1 SET domain ANAPC4_WD40 PF12894.7 GAM37808.1 - 0.00038 20.7 0.0 0.05 13.9 0.0 3.5 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain zf-MYND PF01753.18 GAM37808.1 - 0.0073 16.4 4.9 0.0073 16.4 4.9 2.1 2 0 0 2 2 2 1 MYND finger Glucosamine_iso PF01182.20 GAM37809.1 - 7.4e-70 235.3 0.0 1.3e-69 234.6 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ank_2 PF12796.7 GAM37810.1 - 1e-33 115.7 0.0 7.3e-07 29.7 0.0 5.1 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM37810.1 - 6.3e-29 96.8 0.0 0.043 14.4 0.0 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 GAM37810.1 - 2e-25 88.1 0.0 0.044 14.3 0.0 8.4 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 GAM37810.1 - 8.2e-24 83.7 0.0 1.8e-05 25.2 0.1 5.2 5 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM37810.1 - 3.7e-20 71.7 0.4 0.0007 19.8 0.0 6.7 4 3 3 7 7 7 3 Ankyrin repeats (many copies) TRAP_beta PF05753.14 GAM37810.1 - 0.016 14.6 0.0 0.81 9.1 0.0 2.2 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) DUF1965 PF09248.10 GAM37810.1 - 0.077 12.8 3.2 11 5.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1965) AAA_16 PF13191.6 GAM37811.1 - 2.2e-08 34.6 0.2 5.5e-07 30.1 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain PNP_UDP_1 PF01048.20 GAM37811.1 - 5.8e-07 29.0 0.1 1.4e-06 27.8 0.1 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 GAM37811.1 - 1.8e-05 24.7 0.0 3.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GAM37811.1 - 5.8e-05 23.4 0.1 0.00074 19.8 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 GAM37811.1 - 0.0047 17.4 0.0 0.021 15.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 GAM37811.1 - 0.045 13.8 0.2 0.27 11.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAM37811.1 - 0.087 12.1 1.0 14 4.8 0.0 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 GAM37811.1 - 0.13 12.8 0.0 0.77 10.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Nab1 PF04902.12 GAM37811.1 - 0.19 12.1 3.9 0.071 13.5 0.5 2.0 3 0 0 3 3 3 0 Conserved region in Nab1 adh_short_C2 PF13561.6 GAM37812.1 - 8.3e-47 159.7 0.8 1e-46 159.4 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM37812.1 - 2.4e-38 131.6 1.2 2.9e-38 131.3 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 GAM37812.1 - 0.0064 16.4 0.6 0.0088 15.9 0.6 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 GAM37812.1 - 0.0068 16.3 0.1 0.0091 15.9 0.1 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 GAM37812.1 - 0.022 14.9 0.5 0.036 14.2 0.5 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.19 GAM37812.1 - 0.056 12.8 1.1 0.12 11.7 1.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fungal_trans_2 PF11951.8 GAM37813.1 - 4.3e-13 48.8 0.1 8.3e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNase_H PF00075.24 GAM37814.1 - 3.8e-18 66.0 0.1 7.3e-18 65.1 0.1 1.4 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 GAM37814.1 - 0.019 14.8 0.3 14 5.5 0.1 3.2 2 1 0 2 2 2 0 Reverse transcriptase-like Hemerythrin PF01814.23 GAM37815.1 - 9e-12 45.7 0.4 1.2e-11 45.3 0.4 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain MFS_1 PF07690.16 GAM37816.1 - 6.3e-31 107.6 30.9 8.2e-31 107.2 30.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM37816.1 - 5.7e-06 25.9 1.4 5.7e-06 25.9 1.4 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MNHE PF01899.16 GAM37816.1 - 2.4 7.9 5.5 0.87 9.3 1.2 2.3 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit GATase PF00117.28 GAM37818.1 - 0.02 14.7 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I ICL PF00463.21 GAM37819.1 - 1.5e-111 373.5 0.2 2.4e-111 372.8 0.2 1.3 1 1 0 1 1 1 1 Isocitrate lyase family Aminotran_1_2 PF00155.21 GAM37820.1 - 3.2e-11 43.0 0.0 5.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II RRM_1 PF00076.22 GAM37820.1 - 5.5e-05 22.9 0.0 0.014 15.2 0.0 3.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6A PF02046.15 GAM37820.1 - 0.084 13.4 0.9 0.54 10.8 0.1 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa Aminotran_MocR PF12897.7 GAM37820.1 - 0.19 10.5 0.1 0.45 9.3 0.0 1.5 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase MA3 PF02847.17 GAM37821.1 - 2.9e-29 101.3 0.0 8.8e-29 99.8 0.0 1.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 GAM37821.1 - 4.1e-12 46.2 0.1 7.5e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 MIF4G domain MRP-S26 PF14943.6 GAM37821.1 - 0.84 9.5 7.0 0.33 10.8 0.2 2.5 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 DPM2 PF07297.12 GAM37822.1 - 2e-30 104.9 0.8 2.3e-30 104.7 0.8 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 GAM37822.1 - 0.00094 19.1 0.7 0.0011 18.9 0.7 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 GAM37822.1 - 0.0078 16.3 0.2 0.0078 16.3 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) COX14 PF14880.6 GAM37822.1 - 0.0078 16.0 1.6 0.026 14.4 0.1 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly PilX_N PF14341.6 GAM37822.1 - 0.22 11.5 1.9 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 PilX N-terminal LapA_dom PF06305.11 GAM37822.1 - 0.27 11.1 0.1 0.27 11.1 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain NFACT-R_2 PF18297.1 GAM37823.1 - 0.066 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 NFACT protein RNA binding domain HD PF01966.22 GAM37824.1 - 6e-05 23.2 0.6 0.00021 21.5 0.1 2.0 2 1 0 2 2 2 1 HD domain Holin_BhlA PF10960.8 GAM37824.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 BhlA holin family Dynamin_M PF01031.20 GAM37825.1 - 3.9e-34 118.2 3.6 3.9e-34 118.2 3.6 2.0 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 GAM37825.1 - 3.5e-15 56.5 0.0 1.1e-14 54.8 0.0 1.9 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 GAM37825.1 - 0.00019 21.5 1.0 0.0024 18.0 0.2 3.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain PriX PF18689.1 GAM37825.1 - 0.022 15.1 0.6 0.2 12.0 0.0 2.8 3 1 1 4 4 4 0 Primase X Abhydrolase_2 PF02230.16 GAM37826.1 - 3.9e-26 92.2 0.0 5.6e-17 62.3 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 GAM37826.1 - 7.9e-05 22.2 0.0 0.00018 21.1 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Nop14 PF04147.12 GAM37826.1 - 0.00016 20.1 9.3 0.00017 20.0 9.3 1.1 1 0 0 1 1 1 1 Nop14-like family SpoIIIAH PF12685.7 GAM37826.1 - 0.021 14.7 5.3 0.03 14.2 5.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein SAPS PF04499.15 GAM37826.1 - 0.023 13.5 0.4 0.033 13.0 0.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hydrolase_4 PF12146.8 GAM37826.1 - 0.031 13.5 0.0 0.078 12.2 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Sigma70_ner PF04546.13 GAM37826.1 - 0.05 13.5 8.7 0.076 12.9 8.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CPSF100_C PF13299.6 GAM37826.1 - 0.26 11.5 2.0 0.44 10.7 2.0 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DNA_pol_phi PF04931.13 GAM37826.1 - 0.31 9.1 31.3 0.47 8.5 31.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4637 PF15470.6 GAM37826.1 - 0.79 9.4 15.2 1.3 8.7 15.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) SDA1 PF05285.12 GAM37826.1 - 0.91 8.9 19.4 1.3 8.4 19.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GAM37826.1 - 1.2 7.3 15.4 1.6 6.9 15.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2151 PF10221.9 GAM37826.1 - 1.7 7.2 4.0 2.2 6.8 4.0 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator BUD22 PF09073.10 GAM37826.1 - 1.9 7.8 21.9 2.5 7.3 21.9 1.1 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 GAM37826.1 - 2.1 7.4 31.0 0.46 9.6 26.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TraH_2 PF06871.11 GAM37826.1 - 4.5 6.9 5.4 10 5.7 5.4 1.5 1 0 0 1 1 1 0 TraH_2 CobT PF06213.12 GAM37826.1 - 5.8 6.2 20.9 8.4 5.7 20.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sporozoite_P67 PF05642.11 GAM37826.1 - 7.9 4.4 10.1 10 4.0 10.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Helicase_C PF00271.31 GAM37828.1 - 6.2e-20 71.6 0.3 2.6e-19 69.6 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM37828.1 - 5.4e-19 68.8 0.0 1.1e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM37828.1 - 7.5e-15 55.1 0.0 2.1e-14 53.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 GAM37828.1 - 0.016 14.4 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 GAM37828.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase UIM PF02809.20 GAM37828.1 - 0.041 13.8 0.4 0.15 12.0 0.4 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif AAA_22 PF13401.6 GAM37828.1 - 0.1 12.9 0.0 0.3 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain F_actin_cap_B PF01115.17 GAM37829.1 - 8.5e-106 352.9 0.0 9.9e-106 352.7 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 GAM37829.1 - 0.068 12.6 0.0 0.19 11.1 0.0 1.8 1 1 1 2 2 2 0 F-actin capping protein alpha subunit Med11 PF10280.9 GAM37830.1 - 8e-44 149.4 0.2 9.8e-44 149.1 0.2 1.1 1 0 0 1 1 1 1 Mediator complex protein Paramyxo_ncap PF00973.19 GAM37830.1 - 0.016 14.1 0.1 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein WD40 PF00400.32 GAM37831.1 - 2.3e-43 145.3 22.6 5.7e-09 36.5 0.1 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 GAM37831.1 - 1.9e-40 138.1 0.1 2.8e-40 137.6 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 GAM37831.1 - 4.3e-10 39.8 0.6 0.011 16.0 0.0 4.8 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 GAM37831.1 - 6.5e-07 29.1 0.0 1.6e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 GAM37831.1 - 0.00034 19.4 1.8 0.17 10.5 0.0 3.5 3 1 1 4 4 4 2 Nucleoporin Nup120/160 DUF4550 PF15084.6 GAM37831.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4550) Abhydrolase_6 PF12697.7 GAM37832.1 - 2.1e-21 77.6 0.4 3.4e-21 76.9 0.1 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM37832.1 - 1.1e-05 25.2 0.0 3.4e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM37832.1 - 0.011 15.0 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 GAM37832.1 - 0.027 14.2 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 GAM37832.1 - 0.052 12.5 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2417 PF10329.9 GAM37833.1 - 5.2e-84 281.4 0.6 7.6e-84 280.8 0.6 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Peptidase_U4 PF03419.13 GAM37833.1 - 0.034 13.5 2.2 0.077 12.3 2.2 1.5 1 0 0 1 1 1 0 Sporulation factor SpoIIGA FA_desaturase PF00487.24 GAM37833.1 - 0.32 10.8 2.5 1.4 8.7 0.2 2.5 2 1 0 3 3 3 0 Fatty acid desaturase NPL4 PF05021.15 GAM37834.1 - 1e-138 461.9 0.0 1.2e-138 461.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 GAM37834.1 - 1.2e-69 233.0 0.1 1.9e-69 232.4 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 GAM37834.1 - 0.00016 22.1 0.0 0.00056 20.3 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Flavodoxin_2 PF02525.17 GAM37835.1 - 1.3e-07 31.5 0.0 1.7e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 GAM37835.1 - 3.4e-06 26.9 0.0 4.4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 GAM37835.1 - 9e-05 22.7 0.1 0.0038 17.4 0.1 2.3 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 GAM37835.1 - 0.038 14.2 0.0 0.23 11.7 0.0 1.9 1 1 1 2 2 2 0 Flavodoxin domain zf-CCCH PF00642.24 GAM37836.1 - 2.3e-16 59.2 35.6 2e-06 27.6 1.8 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GAM37836.1 - 2.2e-11 44.4 27.3 0.00011 22.8 1.6 5.3 1 1 4 5 5 5 5 Torus domain zf_CCCH_4 PF18345.1 GAM37836.1 - 3.3e-10 39.7 36.2 0.003 17.5 2.5 5.3 5 0 0 5 5 5 4 Zinc finger domain zf-CCCH_4 PF18044.1 GAM37836.1 - 6.3e-05 22.7 25.3 7.8e-05 22.4 2.3 4.5 4 0 0 4 4 4 3 CCCH-type zinc finger CitT PF12431.8 GAM37836.1 - 0.17 12.3 0.0 0.6 10.5 0.0 1.9 1 0 0 1 1 1 0 Transcriptional regulator Glyco_hydro_18 PF00704.28 GAM37837.1 - 2.3e-71 241.1 0.0 2.6e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PNP_UDP_1 PF01048.20 GAM37838.1 - 5.8e-09 35.6 0.9 3.3e-08 33.1 0.9 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily DUF3712 PF12505.8 GAM37840.1 - 5.2e-33 114.0 6.1 6.2e-33 113.7 1.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 GAM37840.1 - 0.17 12.5 2.0 1.9 9.0 0.2 2.8 2 1 0 2 2 2 0 Late embryogenesis abundant protein SecD-TM1 PF13721.6 GAM37840.1 - 0.19 12.2 0.9 18 5.9 0.0 2.5 2 0 0 2 2 2 0 SecD export protein N-terminal TM region Sel1 PF08238.12 GAM37841.1 - 1.9e-10 41.0 12.1 0.0077 16.9 0.0 4.4 4 1 0 4 4 4 3 Sel1 repeat Far-17a_AIG1 PF04750.14 GAM37842.1 - 3.1e-05 23.4 22.4 0.00023 20.6 21.0 2.4 1 1 1 2 2 2 1 FAR-17a/AIG1-like protein DUF5134 PF17197.4 GAM37842.1 - 0.7 9.8 3.3 2.4 8.0 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) S-antigen PF05756.11 GAM37842.1 - 1.1 9.7 0.0 1.1 9.7 0.0 2.8 3 0 0 3 3 3 0 S-antigen protein p450 PF00067.22 GAM37843.1 - 2.7e-16 59.4 0.0 3e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 GAM37844.1 - 1.5e-27 96.4 0.2 2.6e-14 52.8 0.0 2.2 1 1 1 2 2 2 2 Cytochrome P450 Aldo_ket_red PF00248.21 GAM37844.1 - 7e-20 71.4 0.0 1.5e-19 70.3 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family His_Phos_2 PF00328.22 GAM37846.1 - 2.5e-24 86.4 0.0 3.6e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1776 PF08643.10 GAM37847.1 - 4.9e-98 328.2 0.0 6e-98 327.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 GAM37847.1 - 0.0002 20.9 0.0 0.01 15.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37847.1 - 0.0024 17.5 0.0 0.28 10.7 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase CoA_binding_3 PF13727.6 GAM37847.1 - 0.14 12.1 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 CoA-binding domain DUF2569 PF10754.9 GAM37848.1 - 0.16 12.4 3.6 0.28 11.6 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) EF-hand_1 PF00036.32 GAM37849.1 - 9.2e-36 118.7 12.6 2e-10 39.5 0.2 4.6 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 GAM37849.1 - 1.3e-30 105.7 2.8 1.8e-16 60.3 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAM37849.1 - 2e-29 99.0 6.5 2.4e-09 36.4 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 GAM37849.1 - 2.8e-26 91.1 8.5 2.8e-14 52.7 0.4 3.5 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 GAM37849.1 - 1.9e-20 71.4 9.9 1.3e-06 27.7 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 GAM37849.1 - 4.7e-15 55.7 0.6 1.9e-07 31.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GAM37849.1 - 3.1e-07 30.3 0.2 0.0045 16.9 0.1 2.1 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 GAM37849.1 - 6.4e-06 26.1 0.0 0.005 16.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 GAM37849.1 - 7.4e-06 26.8 0.1 0.00017 22.4 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 GAM37849.1 - 0.00022 21.5 0.2 0.065 13.6 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1456 PF07308.13 GAM37849.1 - 0.0038 17.5 0.9 0.23 11.8 0.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1456) FGAR-AT_linker PF18072.1 GAM37849.1 - 0.0041 17.6 0.3 3.1 8.4 0.1 2.7 2 1 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain EF-hand_14 PF17959.1 GAM37849.1 - 0.0057 17.0 0.0 1.2 9.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain DUF3349 PF11829.8 GAM37849.1 - 0.0062 17.3 0.6 0.63 10.9 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3349) EF-hand_10 PF14788.6 GAM37849.1 - 0.0067 16.3 0.4 0.051 13.4 0.1 2.3 2 0 0 2 2 2 1 EF hand Toprim_2 PF13155.6 GAM37849.1 - 0.01 16.3 0.7 0.7 10.4 0.0 2.4 1 1 0 2 2 2 0 Toprim-like MgtE_N PF03448.17 GAM37849.1 - 0.013 16.1 1.8 0.5 11.0 0.1 2.2 2 0 0 2 2 2 0 MgtE intracellular N domain VbhA PF18495.1 GAM37849.1 - 0.015 15.2 1.0 5.6 6.9 0.0 3.5 4 0 0 4 4 3 0 Antitoxin VbhA Caleosin PF05042.13 GAM37849.1 - 0.015 15.2 0.1 2.5 8.0 0.0 2.8 2 1 1 3 3 3 0 Caleosin related protein DUF5580 PF17743.1 GAM37849.1 - 0.021 13.4 0.0 0.021 13.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) TerB PF05099.13 GAM37849.1 - 0.024 14.6 1.8 0.3 11.0 0.2 2.3 2 1 0 2 2 2 0 Tellurite resistance protein TerB Dockerin_1 PF00404.18 GAM37849.1 - 0.033 14.4 1.6 2.5 8.4 0.1 2.7 2 1 0 2 2 2 0 Dockerin type I domain DUF1811 PF08838.10 GAM37849.1 - 0.042 14.1 0.4 0.52 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) RNA_pol_Rpb4 PF03874.16 GAM37849.1 - 0.047 14.0 2.2 4.7 7.6 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb4 Peptidase_M24 PF00557.24 GAM37849.1 - 0.06 13.0 0.0 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Metallopeptidase family M24 Toprim_4 PF13662.6 GAM37849.1 - 0.083 13.4 0.7 0.96 10.0 0.1 2.4 1 1 0 2 2 2 0 Toprim domain DUF1296 PF06972.11 GAM37849.1 - 0.12 12.5 1.7 0.27 11.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) Phage_tail_S PF05069.13 GAM37849.1 - 0.14 12.0 0.2 0.87 9.4 0.0 2.2 2 1 1 3 3 3 0 Phage virion morphogenesis family Glycos_trans_3N PF02885.17 GAM37849.1 - 0.15 11.9 10.1 6.2 6.7 0.3 5.0 4 2 1 5 5 5 0 Glycosyl transferase family, helical bundle domain Amidase PF01425.21 GAM37850.1 - 2.1e-96 323.7 0.0 2.5e-96 323.4 0.0 1.1 1 0 0 1 1 1 1 Amidase adh_short PF00106.25 GAM37851.1 - 2.5e-05 23.8 0.0 0.0055 16.2 0.0 2.6 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 GAM37851.1 - 0.0014 18.6 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 GAM37851.1 - 0.0096 15.1 0.0 0.024 13.8 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Asparaginase_II PF06089.12 GAM37852.1 - 3.3e-101 338.5 0.2 1.2e-54 185.6 0.0 2.0 1 1 1 2 2 2 2 L-asparaginase II WLM PF08325.10 GAM37853.1 - 7.5e-66 221.9 0.0 1.2e-65 221.1 0.0 1.4 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 GAM37853.1 - 0.00026 20.3 19.1 0.00064 19.0 4.6 3.1 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DUF45 PF01863.17 GAM37853.1 - 0.0018 18.4 1.6 0.0048 17.0 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 Stc1 PF12898.7 GAM37853.1 - 0.0091 16.5 5.0 0.16 12.6 0.8 2.5 2 0 0 2 2 2 1 Stc1 domain DZR PF12773.7 GAM37853.1 - 0.054 13.5 9.9 0.63 10.1 10.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon Peptidase_M54 PF07998.11 GAM37853.1 - 0.071 13.1 0.0 0.16 12.0 0.0 1.5 2 0 0 2 2 2 0 Peptidase family M54 HypA PF01155.19 GAM37853.1 - 0.11 12.6 4.2 5.7 7.0 0.2 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SprT-like PF10263.9 GAM37853.1 - 0.12 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 SprT-like family C1_2 PF03107.16 GAM37853.1 - 0.41 11.0 6.2 3.1 8.2 0.9 2.8 2 0 0 2 2 2 0 C1 domain GLEYA PF10528.9 GAM37854.1 - 6.2e-17 61.8 4.2 1.7e-16 60.4 2.6 2.3 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.12 GAM37854.1 - 1.9e-06 27.8 0.0 3.6e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 PA14 domain YL1_C PF08265.11 GAM37854.1 - 0.011 15.5 3.0 0.034 13.9 3.0 1.8 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Alpha_L_fucos PF01120.17 GAM37855.1 - 1.5e-14 54.3 0.4 2.4e-14 53.5 0.4 1.3 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.6 GAM37855.1 - 0.0015 18.7 0.1 0.007 16.5 0.1 2.0 1 1 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 FAD_binding_3 PF01494.19 GAM37856.1 - 1.1e-24 87.4 0.1 2.2e-20 73.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_11 PF14833.6 GAM37856.1 - 4.5e-08 33.4 0.0 8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Phe_hydrox_dim PF07976.12 GAM37856.1 - 1.1e-07 32.1 0.0 2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_2 PF03446.15 GAM37856.1 - 0.00055 20.1 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF4041 PF13250.6 GAM37856.1 - 0.12 12.3 0.0 13 5.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Collagen_bind_2 PF12904.7 GAM37857.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase F-box-like PF12937.7 GAM37858.1 - 3.7e-06 26.7 0.1 1e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like AIP3 PF03915.13 GAM37858.1 - 0.21 10.7 0.1 2.9 6.9 0.0 2.0 2 0 0 2 2 2 0 Actin interacting protein 3 GFA PF04828.14 GAM37860.1 - 0.0011 19.3 1.5 0.0011 19.3 1.5 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Pkinase PF00069.25 GAM37861.1 - 8.6e-24 84.3 0.0 1.2e-22 80.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM37861.1 - 3.5e-08 33.1 0.0 0.0015 17.8 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GAM37861.1 - 0.092 12.6 0.0 0.27 11.1 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAM37861.1 - 0.17 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DJ-1_PfpI PF01965.24 GAM37862.1 - 1.5e-11 44.4 0.0 1.7e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family SpoIIE PF07228.12 GAM37864.1 - 0.00023 21.2 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 GAM37864.1 - 0.0052 16.5 0.1 0.21 11.2 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 GAM37864.1 - 0.0095 15.6 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Lipase_3 PF01764.25 GAM37865.1 - 1.1e-17 64.3 0.0 1.5e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Fungal_trans_2 PF11951.8 GAM37866.1 - 3.7e-14 52.3 1.7 4.4e-13 48.8 1.4 2.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain F-box PF00646.33 GAM37868.1 - 0.00019 21.2 0.1 0.00071 19.4 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GAM37868.1 - 0.00058 19.7 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like P34-Arc PF04045.14 GAM37869.1 - 1.5e-108 362.1 0.2 1.8e-108 361.8 0.2 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 GAM37869.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) WD40 PF00400.32 GAM37870.1 - 6.4e-52 172.4 24.5 2.6e-07 31.2 0.1 12.0 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.12 GAM37870.1 - 2.3e-21 76.1 0.3 4.8e-21 75.1 0.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Glyco_hydro_43 PF04616.14 GAM37870.1 - 1.6e-19 70.4 4.0 4e-19 69.0 4.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ANAPC4_WD40 PF12894.7 GAM37870.1 - 1.6e-18 66.7 2.1 0.012 15.9 0.0 8.3 6 3 3 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM37870.1 - 7.3e-07 28.4 0.3 0.94 8.4 0.0 5.7 4 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 GAM37870.1 - 0.00036 19.4 1.8 0.057 12.1 0.0 4.4 4 2 1 5 5 5 1 Nup133 N terminal like Nup160 PF11715.8 GAM37870.1 - 0.0029 16.3 11.6 0.037 12.7 0.0 5.6 6 2 1 7 7 7 1 Nucleoporin Nup120/160 WD40_like PF17005.5 GAM37870.1 - 0.0054 16.1 0.0 3 7.1 0.0 3.5 4 0 0 4 4 4 1 WD40-like domain RRP36 PF06102.12 GAM37870.1 - 9.6 6.1 7.5 15 5.5 1.0 2.3 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 MFS_1 PF07690.16 GAM37871.1 - 6.9e-18 64.7 50.6 8.5e-17 61.1 33.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM37871.1 - 2e-07 30.3 13.7 2e-07 30.3 13.7 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter Fcf1 PF04900.12 GAM37872.1 - 3.7e-16 59.3 0.1 9.1e-15 54.9 0.1 2.4 1 1 0 1 1 1 1 Fcf1 DUF4551 PF15087.6 GAM37872.1 - 0.97 8.2 9.7 1.3 7.8 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Cmc1 PF08583.10 GAM37873.1 - 1e-17 63.9 4.1 1.3e-17 63.5 4.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like WD40 PF00400.32 GAM37874.1 - 2.7e-16 59.7 3.9 0.00065 20.5 0.2 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM37874.1 - 2.4e-06 27.8 0.1 0.012 15.9 0.1 4.7 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM37874.1 - 3.1e-06 26.1 1.2 0.00069 18.4 0.1 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF4241 PF14025.6 GAM37874.1 - 0.056 13.7 3.0 0.15 12.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4241) Astro_capsid_p PF12226.8 GAM37874.1 - 3.9 6.5 14.3 7.8 5.5 14.3 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Abhydrolase_1 PF00561.20 GAM37875.1 - 1.3e-21 77.5 0.0 1.2e-19 71.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM37875.1 - 2.5e-20 72.8 0.0 1e-19 70.8 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM37875.1 - 7.8e-16 59.3 0.0 1.1e-15 58.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAM37875.1 - 4.8e-09 36.0 0.0 0.00076 19.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ndr PF03096.14 GAM37875.1 - 0.00016 20.5 0.0 0.00027 19.8 0.0 1.5 1 1 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.13 GAM37875.1 - 0.00027 20.9 0.0 0.0012 18.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 GAM37875.1 - 0.0016 18.2 0.0 0.0058 16.3 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 GAM37875.1 - 0.0024 18.0 0.0 0.006 16.7 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein DUF2920 PF11144.8 GAM37875.1 - 0.043 13.0 0.0 0.058 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Peptidase_S28 PF05577.12 GAM37875.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Ecl1 PF12855.7 GAM37877.1 - 0.31 12.2 9.1 0.37 12.0 9.1 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins RRN3 PF05327.11 GAM37881.1 - 3e-175 584.0 0.0 3e-175 584.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Abhydrolase_3 PF07859.13 GAM37882.1 - 2.5e-44 151.7 0.1 1e-43 149.6 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAM37882.1 - 1.6e-08 33.9 0.0 4.9e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.16 GAM37882.1 - 0.0033 17.2 0.0 0.022 14.6 0.0 2.2 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 GAM37882.1 - 0.0095 15.4 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF2974 PF11187.8 GAM37882.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AXE1 PF05448.12 GAM37882.1 - 0.025 13.3 0.1 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Sugar_tr PF00083.24 GAM37883.1 - 4.3e-68 230.2 28.7 4.9e-68 230.0 28.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37883.1 - 8.4e-20 71.0 33.6 7e-12 44.9 15.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LEA_1 PF03760.15 GAM37883.1 - 0.091 13.4 0.8 0.17 12.5 0.8 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 Glyco_hydro_38N PF01074.22 GAM37884.1 - 1.5e-85 287.0 1.8 2.4e-85 286.4 1.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAM37884.1 - 1.7e-53 181.8 0.1 7e-53 179.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GAM37884.1 - 2e-25 88.8 0.0 4.3e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 GAM37884.1 - 9.6e-11 41.7 0.0 3.1e-10 40.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_79C PF16862.5 GAM37885.1 - 8.2e-23 81.2 2.5 8.2e-23 81.2 2.5 2.4 3 0 0 3 3 3 1 Glycosyl hydrolase family 79 C-terminal beta domain Bac_rhamnosid6H PF17389.2 GAM37886.1 - 9.8e-17 61.2 0.0 1.8e-16 60.4 0.0 1.4 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_36 PF17167.4 GAM37886.1 - 6.9e-05 21.7 0.0 0.0001 21.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Bac_rhamnosid_N PF08531.10 GAM37886.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_2_N PF02837.18 GAM37886.1 - 0.0032 17.4 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain tRNA-synt_2 PF00152.20 GAM37887.1 - 2e-72 244.0 0.0 3.2e-72 243.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 GAM37887.1 - 8.9e-20 70.9 0.0 1.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 GAM37887.1 - 0.0017 18.3 0.0 0.0045 17.0 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAM37887.1 - 0.067 12.7 0.1 7.5 6.0 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) LXG PF04740.12 GAM37888.1 - 0.033 13.9 0.2 0.059 13.1 0.2 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily NAD_binding_10 PF13460.6 GAM37889.1 - 3.2e-19 69.5 0.0 5.5e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM37889.1 - 7.5e-06 25.7 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Peptidase_S9 PF00326.21 GAM37889.1 - 0.0031 17.0 0.0 0.0068 15.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Semialdhyde_dh PF01118.24 GAM37889.1 - 0.0038 17.6 0.0 0.0088 16.5 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAM37889.1 - 0.0085 15.1 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM37889.1 - 0.025 14.0 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Hydrolase_4 PF12146.8 GAM37889.1 - 0.032 13.5 0.0 0.12 11.6 0.0 1.9 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM37889.1 - 0.071 12.7 0.0 1.5 8.4 0.0 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM37889.1 - 0.079 13.6 0.2 0.16 12.6 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family KR PF08659.10 GAM37889.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 KR domain FAD_binding_3 PF01494.19 GAM37890.1 - 8.5e-11 41.7 0.0 7.3e-10 38.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM37890.1 - 2.2e-05 24.6 0.2 6.1e-05 23.2 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAM37890.1 - 3.3e-05 23.3 0.2 6.4e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAM37890.1 - 0.0056 16.0 0.5 0.014 14.6 0.4 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM37890.1 - 0.01 15.9 1.0 3.7 7.5 0.2 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 GAM37890.1 - 0.016 14.3 0.4 0.029 13.5 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 GAM37890.1 - 0.024 13.9 0.1 0.04 13.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAM37890.1 - 0.056 12.7 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase MDMPI_N PF11716.8 GAM37890.1 - 0.15 12.7 0.0 15 6.2 0.0 2.2 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain DAO PF01266.24 GAM37890.1 - 0.38 10.3 2.6 0.77 9.3 0.7 2.0 1 1 0 2 2 2 0 FAD dependent oxidoreductase MFS_1 PF07690.16 GAM37891.1 - 2e-34 119.1 33.6 5.6e-31 107.7 18.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 GAM37891.1 - 2.9e-25 89.0 0.0 4.1e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GST_N_3 PF13417.6 GAM37893.1 - 1.6e-14 54.0 0.1 3.2e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAM37893.1 - 3.5e-13 49.7 0.1 1.1e-12 48.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM37893.1 - 1.3e-12 47.7 0.0 2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM37893.1 - 1.1e-10 41.7 0.0 3e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM37893.1 - 1.9e-10 40.8 0.0 3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM37893.1 - 3.1e-07 30.3 0.0 5.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GAM37893.1 - 0.01 16.6 0.0 0.036 14.8 0.0 2.0 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain GST_C_5 PF16865.5 GAM37893.1 - 0.071 13.7 0.0 0.88 10.2 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Cu-oxidase_2 PF07731.14 GAM37894.1 - 3.3e-34 117.6 3.9 1.6e-31 108.9 1.6 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 GAM37894.1 - 1.1e-31 110.0 3.9 6.1e-30 104.4 0.1 2.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAM37894.1 - 9.7e-21 74.0 14.6 6.9e-19 68.0 0.4 3.8 3 1 0 3 3 3 2 Multicopper oxidase Methyltransf_11 PF08241.12 GAM37895.1 - 8.2e-11 42.4 0.0 1.5e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM37895.1 - 2.6e-08 34.4 0.0 4.9e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM37895.1 - 1.8e-07 31.1 0.0 4.7e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM37895.1 - 2e-06 28.4 0.1 3.9e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 GAM37895.1 - 0.0074 15.4 0.0 0.0099 15.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 GAM37895.1 - 0.015 15.1 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 GAM37895.1 - 0.054 13.1 0.0 0.068 12.8 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Rab15_effector PF15208.6 GAM37895.1 - 0.076 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Rab15 effector LIP PF03583.14 GAM37895.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Lactamase_B PF00753.27 GAM37896.1 - 4e-15 56.3 5.0 1.5e-13 51.2 5.0 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM37896.1 - 9.5e-06 25.3 1.1 2.5e-05 23.9 1.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAM37896.1 - 0.013 15.4 0.1 0.019 14.8 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain BLACT_WH PF17778.1 GAM37896.1 - 0.053 13.5 1.5 0.21 11.6 0.1 2.7 3 1 0 3 3 3 0 Beta-lactamase associated winged helix domain DUF2291 PF10054.9 GAM37896.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) ketoacyl-synt PF00109.26 GAM37897.1 - 4.3e-75 252.6 0.0 8.1e-75 251.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 GAM37897.1 - 2.3e-48 165.0 0.0 1.9e-45 155.5 0.0 3.5 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 GAM37897.1 - 2e-44 152.4 0.0 3.8e-44 151.5 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM37897.1 - 1.3e-33 115.5 0.9 3.3e-33 114.2 0.9 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 GAM37897.1 - 2.2e-11 43.9 0.3 5.7e-11 42.6 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 GAM37897.1 - 3.8e-10 39.5 0.0 7.6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 GAM37897.1 - 7.6e-08 32.8 0.0 2.5e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 GAM37897.1 - 6.9e-05 22.3 0.0 0.00018 21.0 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.6 GAM37898.1 - 2.1e-09 38.0 0.0 3.8e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM37898.1 - 2.7e-08 34.3 0.0 5.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM37898.1 - 4.6e-08 33.7 0.0 1e-07 32.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM37898.1 - 4e-06 26.7 0.0 8.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM37898.1 - 1.1e-05 25.3 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM37898.1 - 0.034 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAM37898.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Questin_oxidase PF14027.6 GAM37899.1 - 4.1e-86 289.6 0.0 4.8e-86 289.4 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like Cu-oxidase_2 PF07731.14 GAM37900.1 - 6.3e-44 149.0 6.1 1.3e-35 122.1 0.2 3.9 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAM37900.1 - 2.9e-39 133.7 0.8 2.9e-39 133.7 0.8 3.3 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 GAM37900.1 - 4.4e-30 104.9 0.2 4.4e-30 104.9 0.2 2.4 3 0 0 3 3 3 1 Multicopper oxidase SRR1 PF07985.12 GAM37901.1 - 0.015 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 SRR1 DUF4470 PF14737.6 GAM37902.1 - 4.4e-09 36.4 0.1 9.4e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.17 GAM37902.1 - 8e-07 28.7 7.5 0.00048 20.0 0.6 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM37902.1 - 1.1e-05 25.0 1.3 3.3e-05 23.5 1.3 1.9 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 GAM37902.1 - 6.1e-05 22.7 2.4 0.0048 16.7 0.5 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM37902.1 - 0.00011 22.7 2.1 1.5 9.4 0.2 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM37902.1 - 0.00027 21.5 7.6 0.18 12.7 0.7 4.4 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM37902.1 - 0.00073 20.1 0.8 0.00073 20.1 0.8 2.2 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM37902.1 - 0.03 14.5 0.2 4.7 7.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM37902.1 - 0.037 14.3 9.9 2.9 8.2 0.8 3.9 2 2 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM37902.1 - 0.048 13.5 8.7 1.5 8.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 GAM37902.1 - 0.084 12.6 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 GAM37902.1 - 0.41 10.8 2.4 3.5 7.9 0.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat HLH PF00010.26 GAM37903.1 - 2.3e-13 49.9 0.3 5e-13 48.8 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain BID PF06393.11 GAM37903.1 - 0.15 11.6 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 BH3 interacting domain (BID) Septin PF00735.18 GAM37904.1 - 1.5e-17 63.8 0.3 1.2e-16 60.9 0.3 2.0 1 1 0 1 1 1 1 Septin AAA_16 PF13191.6 GAM37904.1 - 0.004 17.6 0.3 0.012 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 GAM37904.1 - 0.0063 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.13 GAM37904.1 - 0.017 14.3 0.1 0.03 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Gtr1_RagA PF04670.12 GAM37904.1 - 0.03 13.7 0.4 6.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region PRK PF00485.18 GAM37904.1 - 0.032 14.0 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ATPase_2 PF01637.18 GAM37904.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 GAM37904.1 - 0.061 13.5 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAM37904.1 - 0.073 13.6 0.8 0.32 11.5 0.8 2.2 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 GAM37904.1 - 0.098 12.6 0.3 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 GAM37904.1 - 0.13 12.0 0.3 0.29 10.9 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain HSP90 PF00183.18 GAM37905.1 - 6.2e-223 741.4 33.8 7.9e-223 741.0 33.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 GAM37905.1 - 2e-15 57.3 0.1 3.7e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAM37905.1 - 5.3e-12 45.7 0.1 1.6e-11 44.2 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 GAM37905.1 - 0.07 13.2 0.2 0.25 11.3 0.2 1.9 1 0 0 1 1 1 0 Tumour suppressor protein NTF2 PF02136.20 GAM37907.1 - 3.4e-26 92.2 0.3 5.4e-26 91.5 0.3 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 GAM37907.1 - 3.7e-08 33.1 0.0 6.3e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GFA PF04828.14 GAM37909.1 - 3e-08 33.9 0.1 7.7e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Ferritin_2 PF13668.6 GAM37910.1 - 5.1e-07 30.0 2.2 6.1e-06 26.5 0.4 2.2 2 0 0 2 2 2 2 Ferritin-like domain Ank_2 PF12796.7 GAM37911.1 - 3.3e-51 171.8 14.1 1.6e-15 57.5 0.1 5.9 2 1 3 6 6 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM37911.1 - 3.1e-49 164.7 9.4 2.4e-10 40.7 0.1 7.8 4 3 4 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM37911.1 - 8.6e-44 147.0 13.9 8.9e-10 38.6 0.1 8.6 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM37911.1 - 2.6e-39 128.7 11.2 0.00016 21.8 0.0 10.4 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 GAM37911.1 - 2.1e-35 119.6 11.8 5.8e-05 23.4 0.0 9.9 9 0 0 9 9 9 8 Ankyrin repeat AAA_22 PF13401.6 GAM37911.1 - 7.9e-08 32.7 0.0 1.8e-06 28.3 0.0 2.9 2 1 1 3 3 3 1 AAA domain NACHT_N PF17100.5 GAM37911.1 - 2.8e-07 30.6 0.0 5.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 GAM37911.1 - 3.9e-05 23.6 0.0 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAM37911.1 - 5.4e-05 23.6 0.2 0.0003 21.2 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 GAM37911.1 - 0.0029 18.0 0.0 0.0081 16.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 GAM37911.1 - 0.036 14.0 0.0 0.093 12.6 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 GAM37911.1 - 0.12 12.4 0.1 6.2 6.9 0.1 3.1 1 1 0 1 1 1 0 AAA domain DUF3447 PF11929.8 GAM37911.1 - 2.5 8.1 6.7 9.9 6.2 0.0 4.4 3 1 1 5 5 5 0 Domain of unknown function (DUF3447) adh_short_C2 PF13561.6 GAM37912.1 - 1.5e-59 201.4 0.0 2.2e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM37912.1 - 1.5e-49 168.1 0.0 2.1e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM37912.1 - 4.8e-06 26.6 0.0 2e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 KR domain Aconitase PF00330.20 GAM37913.1 - 1.5e-75 255.0 0.0 1.1e-73 248.8 0.0 2.2 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAM37913.1 - 2.7e-14 53.6 0.1 5.3e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain PEP_mutase PF13714.6 GAM37914.1 - 5.7e-48 163.5 5.6 6.6e-48 163.2 5.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 GAM37914.1 - 7.8e-23 80.8 0.4 1.1e-22 80.3 0.4 1.1 1 0 0 1 1 1 1 Isocitrate lyase family S-methyl_trans PF02574.16 GAM37914.1 - 0.037 13.8 0.5 0.077 12.8 0.5 1.4 1 1 0 1 1 1 0 Homocysteine S-methyltransferase MFS_1 PF07690.16 GAM37915.1 - 3.4e-31 108.5 27.8 5e-31 107.9 27.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 GAM37915.1 - 4e-05 22.4 1.3 4e-05 22.4 1.3 3.1 3 1 0 4 4 4 1 MFS/sugar transport protein VHL_C PF17211.3 GAM37915.1 - 0.012 15.6 0.2 0.029 14.4 0.2 1.6 1 0 0 1 1 1 0 VHL box domain DUF4149 PF13664.6 GAM37915.1 - 2 8.8 11.0 1.2 9.5 2.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) UNC-93 PF05978.16 GAM37915.1 - 2.2 8.0 14.7 0.14 11.9 7.3 2.5 2 1 1 3 3 3 0 Ion channel regulatory protein UNC-93 Zn_clus PF00172.18 GAM37916.1 - 4.2e-06 26.8 8.6 7.7e-06 25.9 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3176 PF11374.8 GAM37917.1 - 7.7e-32 109.7 2.0 7.7e-32 109.7 2.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Acetyltransf_1 PF00583.25 GAM37917.1 - 1.2e-19 70.6 0.0 2.2e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM37917.1 - 1.9e-08 34.6 0.0 3.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM37917.1 - 1e-07 31.9 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAM37917.1 - 0.0015 19.2 0.0 0.003 18.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM37917.1 - 0.022 14.7 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein SpoIIM PF01944.17 GAM37917.1 - 0.024 14.7 0.4 0.024 14.7 0.4 2.5 2 1 0 2 2 2 0 Stage II sporulation protein M Acetyltransf_CG PF14542.6 GAM37917.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TPR_17 PF13431.6 GAM37918.1 - 4.8e-05 23.5 2.0 0.63 10.5 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM37918.1 - 0.036 14.2 5.2 3.8 7.9 0.2 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM37918.1 - 0.067 13.0 2.0 3.1 7.8 0.2 3.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM37918.1 - 0.071 12.8 6.5 0.62 9.8 0.0 4.5 5 0 0 5 5 5 0 TPR repeat TPR_10 PF13374.6 GAM37918.1 - 0.096 12.6 0.6 14 5.7 0.1 3.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM37918.1 - 0.71 10.2 5.1 7.8 7.0 0.2 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat DALR_2 PF09190.11 GAM37918.1 - 1 9.9 3.7 18 5.9 0.1 3.6 3 0 0 3 3 3 0 DALR domain TPR_14 PF13428.6 GAM37918.1 - 1.7 9.6 10.5 29 5.8 0.2 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat Nnf1 PF03980.14 GAM37919.1 - 2.9e-31 108.1 3.8 2.9e-31 108.1 3.8 2.0 2 1 1 3 3 3 1 Nnf1 Dicty_CAR PF05462.11 GAM37919.1 - 1.1e-12 47.7 6.7 1.1e-12 47.7 6.7 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 GAM37919.1 - 6.4e-07 28.9 6.8 1e-06 28.3 6.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.8 GAM37919.1 - 0.00039 20.2 11.0 0.00067 19.5 11.0 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Lir1 PF07207.11 GAM37919.1 - 0.14 12.4 0.8 0.43 10.8 0.8 1.8 1 0 0 1 1 1 0 Light regulated protein Lir1 Pkinase PF00069.25 GAM37920.1 - 3.6e-75 252.7 0.0 4.4e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM37920.1 - 3.7e-37 128.0 0.0 5.1e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAM37920.1 - 3.1e-05 23.1 0.0 0.00027 20.0 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAM37920.1 - 0.0016 17.8 0.4 0.016 14.6 0.1 2.4 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.14 GAM37920.1 - 0.017 14.5 0.4 0.017 14.5 0.4 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gln_amidase PF15644.6 GAM37920.1 - 0.021 15.9 0.0 0.05 14.6 0.0 1.6 1 0 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase APH PF01636.23 GAM37920.1 - 0.063 13.2 0.0 0.063 13.2 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAM37920.1 - 0.084 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SIR2 PF02146.17 GAM37921.1 - 1.2e-30 106.8 0.0 1.8e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Rimk_N PF18030.1 GAM37921.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 RimK PreATP-grasp domain Cation_efflux PF01545.21 GAM37922.1 - 3.9e-57 193.2 5.9 5e-57 192.9 5.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAM37922.1 - 6.1e-06 26.3 0.1 1.3e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Pyr_redox PF00070.27 GAM37923.1 - 0.00018 22.0 0.0 0.00027 21.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 GAM37923.1 - 0.00025 20.6 0.1 0.00029 20.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 GAM37923.1 - 0.018 14.3 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 GAM37923.1 - 0.069 13.6 0.0 0.076 13.5 0.0 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 GAM37923.1 - 0.077 12.2 0.0 0.08 12.2 0.0 1.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAM37923.1 - 0.12 11.5 0.1 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 GAM37923.1 - 0.22 10.6 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 GAM37923.1 - 0.22 10.2 0.1 0.26 10.0 0.1 1.0 1 0 0 1 1 1 0 HI0933-like protein Polysacc_synt_2 PF02719.15 GAM37923.1 - 0.24 10.5 0.0 0.29 10.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FGGY_C PF02782.16 GAM37924.1 - 2.2e-32 112.4 0.0 1e-31 110.3 0.0 2.0 2 1 1 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GAM37924.1 - 1.2e-17 64.3 0.0 2.6e-12 46.8 0.0 2.3 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.12 GAM37925.1 - 3.1e-40 137.7 1.9 2.5e-39 134.7 0.0 3.3 4 1 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 GAM37925.1 - 0.052 13.8 0.0 9.2 6.8 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat INTS5_N PF14837.6 GAM37925.1 - 0.066 12.8 0.0 0.22 11.1 0.0 1.9 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus Amidase_3 PF01520.18 GAM37925.1 - 0.16 12.1 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase DUF4844 PF16133.5 GAM37925.1 - 0.2 12.2 0.8 12 6.4 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) Esterase PF00756.20 GAM37926.1 - 7e-51 173.3 0.0 8.6e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 GAM37926.1 - 5.2e-07 29.3 0.1 8.5e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 GAM37926.1 - 1.6e-05 24.6 0.0 0.00023 20.7 0.0 2.0 2 0 0 2 2 2 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 GAM37926.1 - 0.00016 21.0 0.0 0.00044 19.6 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 GAM37926.1 - 0.005 16.7 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 GAM37926.1 - 0.024 15.2 0.1 0.033 14.8 0.1 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 GAM37926.1 - 0.025 14.4 0.0 0.11 12.3 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 GAM37926.1 - 0.079 11.9 0.0 0.12 11.3 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 GAM37926.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 GAM37926.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.20 GAM37926.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_C50 PF03568.17 GAM37927.1 - 4.3e-152 506.8 0.3 2.3e-151 504.4 0.0 2.4 2 0 0 2 2 2 1 Peptidase family C50 CHAT PF12770.7 GAM37927.1 - 3.8e-05 23.2 0.1 0.0021 17.5 0.0 3.2 2 1 0 3 3 3 1 CHAT domain RPN7 PF10602.9 GAM37927.1 - 0.004 16.9 5.2 0.2 11.3 0.1 3.5 3 0 0 3 3 3 2 26S proteasome subunit RPN7 TPR_7 PF13176.6 GAM37927.1 - 0.059 13.4 3.0 38 4.6 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM37927.1 - 0.99 9.7 18.5 0.2 12.0 0.2 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM37927.1 - 1.5 9.8 13.7 1e+02 4.1 0.1 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF5321 PF17254.2 GAM37928.1 - 1.3e-59 200.2 5.0 1.5e-59 200.0 5.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) Glt_symporter PF03616.14 GAM37928.1 - 0.17 10.5 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Tmemb_9 PF05434.11 GAM37928.1 - 0.2 11.5 1.1 0.31 10.9 1.1 1.4 1 0 0 1 1 1 0 TMEM9 MSC PF09402.10 GAM37928.1 - 3.6 7.0 6.9 1.5 8.2 2.3 1.9 1 1 1 2 2 2 0 Man1-Src1p-C-terminal domain Zn_clus PF00172.18 GAM37929.1 - 7.9e-06 25.9 10.9 1.4e-05 25.2 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 GAM37930.1 - 5.2e-52 176.9 0.0 6.3e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PriA_3primeBD PF17764.1 GAM37930.1 - 0.047 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 3′ DNA-binding domain (3′BD) RHH_5 PF07878.11 GAM37930.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 AAA_12 PF13087.6 GAM37931.1 - 3.7e-40 137.7 0.0 7.1e-40 136.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAM37931.1 - 1.1e-24 87.7 0.0 3.7e-24 85.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM37931.1 - 2.3e-10 41.0 0.0 1.7e-09 38.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAM37931.1 - 1.7e-06 27.9 0.5 0.00056 19.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 GAM37931.1 - 0.00011 21.6 0.5 0.43 9.8 0.1 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) zf-CCCH PF00642.24 GAM37931.1 - 0.0018 18.1 2.8 0.0047 16.8 2.8 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Adeno_IVa2 PF02456.15 GAM37931.1 - 0.019 13.8 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_22 PF13401.6 GAM37931.1 - 0.025 14.8 0.6 1.6 9.0 0.0 3.1 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 GAM37931.1 - 0.033 14.2 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 GAM37931.1 - 0.046 12.8 0.0 0.093 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 GAM37931.1 - 0.049 13.4 0.4 2.4 7.8 0.0 3.3 3 1 1 4 4 4 0 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 GAM37931.1 - 0.11 12.3 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain CHS5_N PF16892.5 GAM37931.1 - 0.22 11.5 1.3 0.7 9.9 0.0 2.4 3 0 0 3 3 3 0 Chitin biosynthesis protein CHS5 N-terminus p450 PF00067.22 GAM37933.1 - 1.3e-48 165.9 0.0 1.4e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.19 GAM37934.1 - 8.5e-36 123.5 0.0 3.3e-20 72.0 0.1 3.0 2 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAM37934.1 - 5.1e-16 58.8 0.1 6e-10 38.9 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM37934.1 - 1.5e-12 47.4 0.0 3.2e-12 46.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM37934.1 - 1.8e-11 44.2 0.0 0.00036 20.2 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM37934.1 - 1.3e-09 38.2 0.0 4.9e-09 36.3 0.0 2.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 GAM37934.1 - 2.6e-09 36.7 0.1 1.8e-07 30.7 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAM37934.1 - 2e-08 34.4 0.0 5.1e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAM37934.1 - 6.8e-07 28.8 0.1 0.00034 19.9 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 GAM37934.1 - 0.00072 18.7 0.0 0.014 14.5 0.1 2.2 1 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAM37934.1 - 0.0012 17.7 0.0 0.0062 15.3 0.0 2.1 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 GAM37934.1 - 0.0023 18.5 0.1 2 9.1 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 GAM37934.1 - 0.0032 16.3 0.0 0.011 14.6 0.0 1.7 2 0 0 2 2 2 1 MCRA family Semialdhyde_dh PF01118.24 GAM37934.1 - 0.042 14.3 0.0 0.34 11.4 0.0 2.4 3 0 0 3 3 2 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.16 GAM37935.1 - 2.2e-31 109.1 22.8 2.2e-31 109.1 22.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Mito_carr PF00153.27 GAM37936.1 - 2.6e-69 229.2 0.1 2.9e-24 84.8 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein OGG_N PF07934.12 GAM37936.1 - 3.8e-36 123.8 0.0 7.9e-36 122.8 0.0 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 GAM37936.1 - 1.3e-15 57.8 0.0 3.4e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein EF-hand_7 PF13499.6 GAM37936.1 - 2e-14 53.8 2.1 8.3e-08 32.6 0.3 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 GAM37936.1 - 9.3e-12 43.9 1.2 6.7e-06 25.6 0.1 5.6 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 GAM37936.1 - 2.6e-11 42.2 4.0 1.9e-05 23.8 0.1 5.5 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.6 GAM37936.1 - 6.2e-08 32.4 0.2 4.4 7.2 0.0 5.2 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GAM37936.1 - 1.5e-05 24.2 0.2 0.0055 16.2 0.1 3.0 2 0 0 2 2 2 1 EF hand HHH PF00633.23 GAM37936.1 - 0.015 15.1 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif YL1 PF05764.13 GAM37936.1 - 0.45 10.6 5.3 0.83 9.7 4.2 1.8 2 0 0 2 2 2 0 YL1 nuclear protein RRM_1 PF00076.22 GAM37937.1 - 7.2e-27 93.0 0.0 1.8e-10 40.4 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM37937.1 - 2.4e-05 24.1 0.1 0.46 10.4 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif 7tm_2 PF00002.24 GAM37938.1 - 0.0027 17.0 15.8 0.0052 16.1 14.7 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Sugar_tr PF00083.24 GAM37939.1 - 2.1e-79 267.5 22.8 2.7e-79 267.2 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM37939.1 - 4.2e-13 49.0 31.4 4.2e-13 49.0 31.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DDDD PF10161.9 GAM37939.1 - 0.12 12.1 1.6 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Putative mitochondrial precursor protein DUF3531 PF12049.8 GAM37939.1 - 0.15 12.0 0.0 0.53 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3531) DUF2456 PF10445.9 GAM37939.1 - 4.5 7.4 11.1 6.1 7.0 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2456) FAD_binding_3 PF01494.19 GAM37940.1 - 2.2e-16 60.1 0.0 3.9e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM37940.1 - 5.1e-09 35.8 0.0 0.0011 18.3 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM37940.1 - 3.2e-07 29.8 0.3 5.6e-07 29.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 GAM37940.1 - 4.3e-06 25.7 0.1 0.0006 18.6 0.3 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 GAM37940.1 - 1.1e-05 25.5 0.3 3e-05 24.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAM37940.1 - 0.00036 21.0 0.3 0.13 12.8 0.6 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM37940.1 - 0.0011 18.7 0.1 0.068 12.7 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 GAM37940.1 - 0.0072 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAM37940.1 - 0.01 15.1 0.4 0.018 14.3 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM37940.1 - 0.023 14.0 0.1 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DUF1344 PF07076.11 GAM37940.1 - 0.087 12.7 0.0 0.48 10.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1344) Amino_oxidase PF01593.24 GAM37940.1 - 0.15 11.3 0.0 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 GAM37940.1 - 0.21 10.9 0.2 0.38 10.1 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAM37940.1 - 0.22 10.8 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.18 GAM37941.1 - 6e-33 114.0 0.1 6e-33 114.0 0.1 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM37941.1 - 0.00016 21.8 10.3 0.00037 20.5 10.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S13_N PF08069.12 GAM37942.1 - 1.2e-29 102.1 0.1 2e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 GAM37942.1 - 2.5e-14 53.2 0.1 3.4e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 GAM37942.1 - 0.017 15.0 0.1 0.042 13.8 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain VRR_NUC PF08774.11 GAM37943.1 - 3.1e-26 91.6 0.1 2.2e-25 88.8 0.0 2.3 2 0 0 2 2 2 1 VRR-NUC domain Rho_N PF07498.12 GAM37943.1 - 0.068 13.1 1.1 0.17 11.8 1.1 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Dpy-30 PF05186.13 GAM37944.1 - 1e-15 57.1 0.2 1.4e-15 56.7 0.2 1.2 1 0 0 1 1 1 1 Dpy-30 motif RRM_1 PF00076.22 GAM37945.1 - 1.7e-19 69.4 0.0 2.4e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM37945.1 - 0.0065 16.1 0.0 0.0095 15.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EPL1 PF10513.9 GAM37946.1 - 3.6e-33 115.2 0.0 9.4e-33 113.8 0.0 1.8 1 0 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.6 GAM37946.1 - 3.3e-32 110.9 8.1 3.3e-32 110.9 8.1 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GAM37946.1 - 8.1e-27 93.3 5.5 8.1e-27 93.3 5.5 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 GAM37946.1 - 1.6e-14 53.1 9.4 7.7e-14 51.0 3.4 2.6 2 0 0 2 2 2 2 PHD-finger PHD PF00628.29 GAM37946.1 - 7.7e-10 38.5 21.3 8.8e-09 35.1 10.0 2.6 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.11 GAM37946.1 - 0.011 16.0 3.2 0.011 16.0 3.2 2.6 2 0 0 2 2 2 0 RING-like domain Bromodomain PF00439.25 GAM37946.1 - 0.035 14.2 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 Bromodomain zf-PHD-like PF15446.6 GAM37946.1 - 0.11 12.1 8.4 0.016 14.8 2.2 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Myb_DNA-bind_6 PF13921.6 GAM37947.1 - 5.1e-07 29.8 4.7 7.9e-07 29.2 0.9 2.3 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAM37947.1 - 0.00058 20.0 1.9 0.0008 19.6 0.2 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GAM37947.1 - 0.92 9.9 6.3 5.1 7.5 1.6 2.7 1 1 2 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Peptidase_M22 PF00814.25 GAM37948.1 - 3.3e-48 164.7 0.0 1.5e-42 146.1 0.0 2.9 2 1 0 2 2 2 2 Glycoprotease family FGGY_C PF02782.16 GAM37948.1 - 0.035 13.8 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain YycC PF14174.6 GAM37948.1 - 0.09 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 YycC-like protein ADH_N PF08240.12 GAM37949.1 - 9.1e-19 67.4 1.1 5e-18 65.0 0.1 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM37949.1 - 9.7e-09 35.3 0.0 1.7e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HET PF06985.11 GAM37950.1 - 6.3e-08 33.1 0.3 4.6e-05 23.8 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 GAM37951.1 - 1.7e-08 34.2 1.4 5.7e-08 32.5 1.4 2.0 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 GAM37951.1 - 4e-07 29.5 0.3 6.5e-06 25.6 0.1 2.6 2 0 0 2 2 2 1 F-box F-box PF00646.33 GAM37951.1 - 0.00047 20.0 1.7 0.00069 19.4 0.2 2.2 2 0 0 2 2 2 1 F-box domain Clp_N PF02861.20 GAM37951.1 - 0.064 13.4 0.2 0.15 12.2 0.2 1.5 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component Flavin_Reduct PF01613.18 GAM37953.1 - 6.3e-24 84.8 0.0 8.1e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain SH3_13 PF18335.1 GAM37953.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain YdfA_immunity PF12127.8 GAM37953.1 - 0.16 11.0 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial DNA_pol3_gamma3 PF12169.8 GAM37954.1 - 0.026 14.4 0.4 0.039 13.8 0.1 1.4 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III Geminin PF07412.12 GAM37954.1 - 0.03 14.1 0.2 0.035 13.9 0.2 1.1 1 0 0 1 1 1 0 Geminin S36_mt PF10937.8 GAM37955.1 - 0.14 13.8 1.5 0.16 13.5 1.5 1.2 1 0 0 1 1 1 0 Ribosomal protein S36, mitochondrial SF3b1 PF08920.10 GAM37956.1 - 1.3e-28 99.9 12.6 1.3e-26 93.4 7.6 3.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 GAM37956.1 - 4.5e-12 46.2 9.1 0.21 12.0 0.1 8.6 5 2 4 10 10 10 4 HEAT repeats HEAT_EZ PF13513.6 GAM37956.1 - 6.7e-11 42.5 0.5 0.041 14.4 0.0 6.8 6 0 0 6 6 6 2 HEAT-like repeat HEAT PF02985.22 GAM37956.1 - 5.3e-10 38.7 10.0 0.088 13.1 0.3 9.0 9 0 0 9 9 9 2 HEAT repeat Cnd1 PF12717.7 GAM37956.1 - 3e-08 33.9 1.2 0.13 12.3 0.0 6.3 5 2 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAM37956.1 - 1.5e-05 23.8 1.1 0.022 13.3 0.1 3.4 3 1 0 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 GAM37956.1 - 5.6e-05 23.7 0.9 6.4 7.4 0.0 5.4 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 GAM37956.1 - 0.00034 20.4 0.3 1.2 8.8 0.0 4.2 5 0 0 5 5 5 2 NUC173 domain UNC45-central PF11701.8 GAM37956.1 - 0.00081 19.4 0.0 0.0036 17.3 0.0 2.0 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central UME PF08064.13 GAM37956.1 - 0.0025 17.7 1.1 8.1 6.4 0.0 5.0 7 0 0 7 7 7 1 UME (NUC010) domain CLASP_N PF12348.8 GAM37956.1 - 0.003 17.2 0.2 0.93 9.0 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal DUF3385 PF11865.8 GAM37956.1 - 0.0045 16.9 4.8 0.22 11.4 0.1 5.0 4 1 1 6 6 6 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 GAM37956.1 - 0.05 12.7 0.0 2 7.4 0.0 3.2 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal DRIM PF07539.12 GAM37956.1 - 0.1 10.9 1.8 7.2 4.8 0.2 3.7 2 1 2 4 4 4 0 Down-regulated in metastasis DUF2052 PF09747.9 GAM37956.1 - 8 6.5 9.2 15 5.6 9.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) zf-met PF12874.7 GAM37957.1 - 5.8e-06 26.5 1.3 1.5e-05 25.2 1.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 GAM37957.1 - 6.1e-06 26.4 4.5 1.9e-05 24.9 4.5 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM37957.1 - 5.2e-05 23.5 4.3 0.16 12.5 1.0 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 GAM37957.1 - 0.0001 22.2 2.4 0.0001 22.2 2.4 1.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAM37957.1 - 0.00026 21.2 1.8 0.00064 19.9 1.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 GAM37957.1 - 0.00042 20.9 3.2 0.0011 19.6 3.2 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAM37957.1 - 0.028 14.8 0.7 0.05 13.9 0.7 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 GAM37957.1 - 0.27 10.3 0.1 0.4 9.8 0.1 1.1 1 0 0 1 1 1 0 Putative actin-like family CT_A_B PF02626.15 GAM37958.1 - 4.6e-78 262.5 0.0 7.1e-78 261.9 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 GAM37958.1 - 1.2e-54 185.1 0.0 2.3e-54 184.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAM37958.1 - 4.5e-37 127.0 0.1 1.9e-36 124.9 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAM37958.1 - 2.9e-29 101.3 0.0 5.5e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CT_C_D PF02682.16 GAM37958.1 - 4e-20 72.4 0.0 9.3e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Dala_Dala_lig_C PF07478.13 GAM37958.1 - 2.3e-08 33.8 0.0 4.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.22 GAM37958.1 - 2.9e-07 30.2 1.2 9.7e-07 28.5 1.2 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_5 PF13549.6 GAM37958.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.22 GAM37958.1 - 0.075 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain SSF PF00474.17 GAM37959.1 - 5.1e-14 51.9 30.1 8.3e-14 51.3 30.1 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family LamB_YcsF PF03746.16 GAM37960.1 - 3.6e-85 285.5 0.1 4.5e-85 285.2 0.1 1.0 1 0 0 1 1 1 1 LamB/YcsF family Amino_oxidase PF01593.24 GAM37961.1 - 2.5e-61 208.4 0.0 3e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM37961.1 - 2.7e-13 49.9 0.1 6.5e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Ribonuc_L-PSP PF01042.21 GAM37961.1 - 1.1e-11 44.8 0.0 1.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP FAD_binding_2 PF00890.24 GAM37961.1 - 4.8e-08 32.5 0.1 8e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAM37961.1 - 6.8e-08 32.3 0.1 1.1e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 GAM37961.1 - 1e-06 28.6 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAM37961.1 - 2.5e-05 23.6 0.1 5.7e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 GAM37961.1 - 3.7e-05 23.1 0.4 6.6e-05 22.3 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 GAM37961.1 - 5.1e-05 22.5 0.0 0.0021 17.2 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAM37961.1 - 7.8e-05 22.1 1.8 0.0011 18.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM37961.1 - 8.7e-05 21.4 0.1 0.00024 19.9 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAM37961.1 - 0.00018 20.8 0.7 0.00032 20.0 0.0 1.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM37961.1 - 0.0013 19.2 0.1 0.003 18.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM37961.1 - 0.0054 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAM37961.1 - 0.058 12.7 0.3 0.23 10.7 0.1 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 GAM37961.1 - 0.082 12.9 1.4 1.1 9.2 0.1 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Aldedh PF00171.22 GAM37962.1 - 2e-74 250.8 1.6 2.2e-54 184.7 1.8 3.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Fungal_trans PF04082.18 GAM37962.1 - 2e-17 63.1 0.1 9.9e-17 60.8 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain SAP PF02037.27 GAM37964.1 - 2.8e-13 49.3 0.5 2.8e-13 49.3 0.5 1.7 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 GAM37964.1 - 7.7e-06 25.6 0.6 7.7e-06 25.6 0.6 2.0 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain Methyltransf_11 PF08241.12 GAM37965.1 - 0.00011 22.8 0.0 0.00031 21.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM37965.1 - 0.0076 16.9 0.0 0.025 15.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain TMEM171 PF15471.6 GAM37965.1 - 0.91 8.5 3.6 2.1 7.2 3.6 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 SSrecog PF03531.14 GAM37966.1 - 2.6e-31 107.3 0.1 2.8e-30 104.0 0.0 2.8 4 0 0 4 4 4 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 GAM37966.1 - 6.9e-31 106.5 0.2 1.8e-29 102.0 0.0 2.9 3 0 0 3 3 3 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 GAM37966.1 - 2.8e-27 95.0 0.1 6.7e-26 90.5 0.0 2.9 3 0 0 3 3 3 1 Histone chaperone Rttp106-like PH_TFIIH PF08567.11 GAM37966.1 - 0.021 15.1 0.0 2.3 8.6 0.0 3.5 4 0 0 4 4 4 0 TFIIH p62 subunit, N-terminal domain FMO-like PF00743.19 GAM37967.1 - 9e-10 37.6 0.1 2.3e-09 36.2 0.1 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAM37967.1 - 1.2e-09 37.9 0.0 1.1e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM37967.1 - 7.5e-09 35.3 0.0 3.6e-07 29.8 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM37967.1 - 1.1e-08 35.1 0.0 2.8e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM37967.1 - 1.2e-07 31.7 0.0 0.00061 19.5 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAM37967.1 - 5.4e-07 29.1 0.1 0.0001 21.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAM37967.1 - 0.0014 18.6 0.4 1.5 8.8 0.0 3.4 4 0 0 4 4 4 2 FAD-NAD(P)-binding Thi4 PF01946.17 GAM37967.1 - 0.0021 17.3 0.0 0.0059 15.9 0.0 1.7 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 GAM37967.1 - 0.02 13.9 0.2 0.12 11.4 0.1 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAM37967.1 - 0.15 11.3 0.1 6.6 5.9 0.0 2.8 3 0 0 3 3 3 0 FAD binding domain MMS1_N PF10433.9 GAM37968.1 - 4.3e-134 447.8 0.1 8.2e-134 446.9 0.0 1.5 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GAM37968.1 - 1.9e-68 231.1 0.0 4e-66 223.6 0.0 3.2 3 0 0 3 3 3 1 CPSF A subunit region PQQ_2 PF13360.6 GAM37968.1 - 0.0059 16.2 0.4 0.0059 16.2 0.4 2.2 2 1 0 2 2 2 1 PQQ-like domain NAD_binding_2 PF03446.15 GAM37969.1 - 1.1e-32 113.4 0.0 1.6e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAM37969.1 - 3e-30 105.0 0.0 5e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 GAM37969.1 - 0.0054 17.3 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent MOR2-PAG1_N PF14222.6 GAM37970.1 - 1.9e-215 717.0 0.0 4.1e-215 715.9 0.0 1.6 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 GAM37970.1 - 1e-92 310.6 0.1 1e-92 310.6 0.1 3.0 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 GAM37970.1 - 5.1e-32 110.6 16.0 8.2e-12 43.6 0.4 3.8 2 1 1 3 3 3 3 Cell morphogenesis central region DPBB_1 PF03330.18 GAM37971.1 - 6.5e-07 29.5 0.5 6.5e-07 29.5 0.5 1.8 2 0 0 2 2 2 1 Lytic transglycolase Aconitase PF00330.20 GAM37971.1 - 0.32 10.0 1.6 0.39 9.7 1.6 1.1 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) Abhydrolase_6 PF12697.7 GAM37972.1 - 3.3e-12 47.5 0.6 4.7e-12 47.0 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM37972.1 - 4.4e-11 42.9 0.0 1e-09 38.4 0.2 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 GAM37972.1 - 1.1e-05 25.2 0.4 1.7e-05 24.6 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase Hydrolase_4 PF12146.8 GAM37972.1 - 2.7e-05 23.5 0.1 0.0003 20.1 0.1 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 GAM37972.1 - 0.0021 17.7 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 GAM37972.1 - 0.009 15.8 0.2 0.013 15.2 0.2 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.16 GAM37972.1 - 0.017 15.0 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 GAM37972.1 - 0.024 14.3 0.4 0.074 12.6 0.4 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF676 PF05057.14 GAM37972.1 - 0.032 13.7 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF900 PF05990.12 GAM37972.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) FAD_binding_1 PF00667.20 GAM37973.1 - 2.3e-65 220.3 0.0 3.4e-65 219.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAM37973.1 - 1.4e-34 119.3 1.3 2.7e-34 118.4 1.3 1.5 1 0 0 1 1 1 1 Flavodoxin RRM_1 PF00076.22 GAM37973.1 - 6.8e-23 80.3 0.0 8.8e-12 44.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_1 PF00175.21 GAM37973.1 - 8.2e-21 74.7 0.0 1.1e-19 71.1 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DnaJ PF00226.31 GAM37974.1 - 3e-13 49.7 2.6 4.6e-13 49.1 0.3 2.5 3 0 0 3 3 3 1 DnaJ domain FKBP26_C PF18046.1 GAM37974.1 - 0.041 14.0 0.1 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 FKBP26_C-terminal DEAD PF00270.29 GAM37975.1 - 4.3e-48 163.4 0.2 1.1e-47 162.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM37975.1 - 3.3e-24 85.4 0.0 1.5e-23 83.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAM37975.1 - 2.8e-10 40.3 0.1 1e-09 38.4 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAM37975.1 - 8.8e-07 29.1 0.0 8.8e-07 29.1 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AA_permease PF00324.21 GAM37976.1 - 7.3e-130 433.8 41.9 8.3e-130 433.6 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM37976.1 - 1.7e-42 145.8 48.6 2.1e-42 145.5 48.6 1.0 1 0 0 1 1 1 1 Amino acid permease zf-HC2 PF13490.6 GAM37976.1 - 0.21 11.9 0.1 0.39 11.0 0.1 1.4 1 0 0 1 1 1 0 Putative zinc-finger MatE PF01554.18 GAM37978.1 - 3.7e-59 199.0 36.3 6e-36 123.5 12.5 2.7 2 1 1 3 3 3 2 MatE RPA_C PF08784.11 GAM37979.1 - 1.3e-20 74.0 0.0 3.3e-20 72.7 0.0 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 GAM37979.1 - 9.1e-06 25.6 0.2 1.5e-05 24.9 0.2 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DEAD PF00270.29 GAM37980.1 - 1.6e-47 161.6 0.1 1.7e-46 158.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM37980.1 - 7.2e-23 81.1 0.1 2.1e-22 79.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 GAM37980.1 - 3.4e-21 75.2 1.3 3.4e-21 75.2 1.3 4.3 5 0 0 5 5 5 1 DBP10CT (NUC160) domain NUDIX PF00293.28 GAM37981.1 - 8.9e-27 93.7 0.0 1.4e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 GAM37983.1 - 2.4e-24 86.1 0.0 3.9e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 GAM37983.1 - 4.5e-12 45.1 4.9 0.0077 16.4 0.1 7.0 6 0 0 6 6 6 3 HEAT repeat WD40 PF00400.32 GAM37983.1 - 2e-07 31.6 7.4 7.2e-05 23.5 0.1 4.8 4 0 0 4 4 3 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 GAM37983.1 - 5.2e-06 25.9 0.0 9.3e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 GAM37983.1 - 0.00014 22.1 0.0 8.4 6.9 0.0 3.9 2 2 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 GAM37983.1 - 0.00039 20.9 1.0 0.2 12.2 0.2 3.9 4 0 0 4 4 3 1 HEAT-like repeat Cnd1 PF12717.7 GAM37983.1 - 0.00061 19.9 0.4 0.03 14.4 0.0 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 GAM37983.1 - 0.021 14.4 0.0 0.061 12.9 0.0 1.8 1 0 0 1 1 1 0 Tti2 family DRIM PF07539.12 GAM37983.1 - 0.025 12.9 0.0 0.044 12.1 0.0 1.3 1 0 0 1 1 1 0 Down-regulated in metastasis RTP1_C1 PF10363.9 GAM37983.1 - 0.041 14.1 0.3 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Ge1_WD40 PF16529.5 GAM37983.1 - 0.042 12.8 0.0 0.21 10.5 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DENN PF02141.21 GAM37984.1 - 3.5e-40 137.9 0.0 7.2e-40 136.9 0.0 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 GAM37984.1 - 3.2e-06 27.8 0.0 1.1e-05 26.1 0.0 2.0 1 0 0 1 1 1 1 uDENN domain BRE1 PF08647.11 GAM37984.1 - 0.28 11.3 14.8 0.43 10.7 4.2 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF3450 PF11932.8 GAM37984.1 - 0.61 9.3 13.7 0.38 10.0 1.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 GAM37984.1 - 1.8 8.6 17.6 0.12 12.4 4.5 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 GAM37984.1 - 8.4 6.7 16.0 2.8 8.2 5.4 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 GAM37984.1 - 9 5.6 17.0 13 5.1 3.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding adh_short_C2 PF13561.6 GAM37985.1 - 6.9e-53 179.6 0.9 8.1e-53 179.4 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM37985.1 - 1.8e-44 151.6 0.4 2.2e-44 151.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM37985.1 - 6.8e-09 35.9 0.0 1.8e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 KR domain RabGAP-TBC PF00566.18 GAM37986.1 - 1.7e-43 148.8 0.0 2.5e-42 145.0 0.0 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Porphobil_deamC PF03900.15 GAM37986.1 - 0.18 12.2 0.0 0.43 11.0 0.0 1.6 1 0 0 1 1 1 0 Porphobilinogen deaminase, C-terminal domain Synaptobrevin PF00957.21 GAM37987.1 - 5.7e-32 109.4 0.0 7.4e-32 109.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAM37987.1 - 1.4e-28 98.7 0.0 2.2e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain T6SS_TssF PF05947.12 GAM37987.1 - 0.18 10.3 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssF CCSMST1 PF15013.6 GAM37987.1 - 0.21 11.8 0.3 0.42 10.8 0.3 1.4 1 0 0 1 1 1 0 CCSMST1 family Ribosomal_L26 PF16906.5 GAM37988.1 - 6.7e-39 132.2 3.1 1e-38 131.6 3.1 1.3 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 GAM37988.1 - 2.2e-07 30.6 1.2 5.2e-07 29.4 1.2 1.7 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.11 GAM37988.1 - 0.059 13.4 0.1 0.073 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) Ost4 PF10215.9 GAM37990.1 - 4e-19 68.1 0.4 5.3e-19 67.7 0.4 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase Acyl_transf_3 PF01757.22 GAM37990.1 - 0.1 11.7 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Acyltransferase family Fungal_trans PF04082.18 GAM37991.1 - 2.8e-17 62.6 0.0 4.3e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM37991.1 - 7.7e-10 38.7 5.1 1.2e-09 38.1 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_MalT PF17874.1 GAM37991.1 - 0.17 11.3 0.2 0.32 10.3 0.2 1.4 1 0 0 1 1 1 0 MalT-like TPR region adh_short PF00106.25 GAM37993.1 - 6.2e-08 32.3 0.0 8.9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM37993.1 - 2.3e-07 30.6 0.0 3.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAM37993.1 - 0.0051 16.3 0.0 0.0074 15.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAM37993.1 - 0.0057 15.8 0.0 0.0072 15.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain ApbA PF02558.16 GAM37993.1 - 0.16 11.6 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ApbA PF02558.16 GAM37994.1 - 5.6e-08 32.6 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 GAM37994.1 - 0.0013 18.0 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM37994.1 - 0.015 15.5 0.4 0.037 14.3 0.4 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM37994.1 - 0.017 14.4 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAA-ATPase_like PF09820.9 GAM37994.1 - 0.03 13.7 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase Baculo_19 PF04798.12 GAM37994.1 - 0.19 11.5 0.1 0.51 10.1 0.1 1.8 1 1 0 1 1 1 0 Baculovirus 19 kDa protein conserved region Ion_trans PF00520.31 GAM37995.1 - 8.9e-07 28.4 27.1 1.4e-06 27.8 27.1 1.2 1 0 0 1 1 1 1 Ion transport protein Sporozoite_P67 PF05642.11 GAM37995.1 - 0.38 8.8 3.7 0.56 8.2 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CPSase_L_D2 PF02786.17 GAM37996.1 - 3.5e-114 379.6 0.1 6.3e-84 280.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 GAM37996.1 - 4e-49 165.7 0.0 8.2e-49 164.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 GAM37996.1 - 3.6e-47 160.6 0.0 8.9e-47 159.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 GAM37996.1 - 3e-46 157.1 0.0 6.7e-46 156.0 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 GAM37996.1 - 4.2e-39 133.7 0.0 9.8e-39 132.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 GAM37996.1 - 2.8e-30 105.5 0.0 7.1e-30 104.2 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 GAM37996.1 - 2.6e-22 78.8 0.0 1e-21 76.9 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 GAM37996.1 - 1e-16 61.1 0.3 1.1e-07 31.6 0.1 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAM37996.1 - 8.3e-16 58.0 0.2 3.5e-07 30.0 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 GAM37996.1 - 7.9e-10 38.6 0.0 0.00017 21.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon DJ-1_PfpI PF01965.24 GAM37996.1 - 5.2e-06 26.3 0.0 0.0028 17.5 0.0 4.3 4 0 0 4 4 4 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 GAM37996.1 - 5.9e-06 26.2 0.6 0.0005 19.9 0.6 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 GAM37996.1 - 1.8e-05 24.8 0.2 0.092 12.8 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 GAM37996.1 - 0.002 17.7 0.0 0.77 9.3 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.19 GAM37996.1 - 0.0032 17.3 0.2 2.4 7.9 0.0 2.9 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AMP-binding PF00501.28 GAM37997.1 - 2.2e-81 273.7 0.0 2.7e-81 273.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM37997.1 - 7.8e-13 49.2 0.1 1.8e-12 48.0 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.27 GAM37998.1 - 2e-24 86.6 0.2 3.4e-11 43.8 0.0 3.8 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 GAM37998.1 - 1.2e-08 35.1 5.7 0.00026 20.9 0.1 3.5 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 GAM37998.1 - 9.7e-07 28.9 0.0 0.063 13.5 0.0 2.7 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 GAM37998.1 - 0.057 13.2 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ploopntkinase1 PF18748.1 GAM37998.1 - 0.068 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 NACHT PF05729.12 GAM37998.1 - 0.13 12.2 0.1 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 GAM37998.1 - 0.19 12.2 11.1 0.69 10.4 0.3 2.5 2 0 0 2 2 2 0 AAA domain NOA36 PF06524.12 GAM37998.1 - 0.97 8.7 8.5 1.8 7.8 8.5 1.3 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 GAM37998.1 - 7 6.4 10.8 22 4.8 10.8 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Ank_2 PF12796.7 GAM37999.1 - 2.1e-64 214.1 1.8 3.6e-13 49.9 0.0 5.6 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM37999.1 - 1.3e-62 207.0 9.8 4.8e-10 39.5 0.0 8.6 2 1 8 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM37999.1 - 3.8e-49 158.9 1.3 0.0021 18.4 0.0 11.1 11 0 0 11 11 11 10 Ankyrin repeat Ank PF00023.30 GAM37999.1 - 3.9e-46 153.5 3.3 0.0026 18.1 0.0 10.4 10 0 0 10 10 10 10 Ankyrin repeat Ank_4 PF13637.6 GAM37999.1 - 5.6e-38 128.8 2.9 2.1e-06 28.1 0.0 7.1 4 2 4 8 8 8 8 Ankyrin repeats (many copies) F-box-like PF12937.7 GAM37999.1 - 0.00034 20.5 0.0 0.00057 19.7 0.0 1.4 1 0 0 1 1 1 1 F-box-like VWA_3_C PF18571.1 GAM37999.1 - 0.002 17.9 12.9 0.46 10.4 0.2 6.4 7 0 0 7 7 7 1 von Willebrand factor type A C-terminal domain 3HCDH_RFF PF18321.1 GAM37999.1 - 0.063 13.7 4.0 1.2 9.6 0.1 4.0 3 3 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain DUF1979 PF09322.10 GAM37999.1 - 0.1 12.5 0.0 3.7 7.5 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1979) IRK_N PF08466.10 GAM37999.1 - 0.21 11.8 4.7 65 3.8 0.0 4.9 6 0 0 6 6 6 0 Inward rectifier potassium channel N-terminal Exo84_C PF16528.5 GAM38000.1 - 2e-69 233.5 0.3 2e-69 233.5 0.3 2.1 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 GAM38000.1 - 3.5e-18 65.5 1.4 3.5e-18 65.5 1.4 2.2 2 0 0 2 2 2 1 Vps51/Vps67 DUF4599 PF15371.6 GAM38000.1 - 0.035 14.6 0.1 0.52 10.9 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4599) HIP1_clath_bdg PF16515.5 GAM38000.1 - 0.23 12.1 6.6 0.46 11.1 4.0 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Med30 PF11315.8 GAM38000.1 - 0.28 11.4 4.1 0.11 12.8 1.1 1.8 2 0 0 2 2 2 0 Mediator complex subunit 30 BST2 PF16716.5 GAM38000.1 - 0.36 11.4 3.6 6.2 7.5 2.3 2.8 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 MAS20 PF02064.15 GAM38001.1 - 1.8e-46 157.4 0.7 2.1e-46 157.2 0.7 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor DUF4199 PF13858.6 GAM38001.1 - 0.068 13.6 0.0 0.092 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) PMC2NT PF08066.12 GAM38001.1 - 0.071 13.8 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 PMC2NT (NUC016) domain MgtE PF01769.16 GAM38002.1 - 0.071 13.5 6.3 0.12 12.8 5.9 1.6 1 1 0 1 1 1 0 Divalent cation transporter SUR7 PF06687.12 GAM38002.1 - 0.19 11.3 4.9 0.37 10.4 4.9 1.5 1 1 0 1 1 1 0 SUR7/PalI family DUF3290 PF11694.8 GAM38002.1 - 0.21 11.6 1.7 2.8 7.9 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) DUF2393 PF09624.10 GAM38002.1 - 1 9.3 5.3 0.17 11.9 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) Claudin_3 PF06653.11 GAM38002.1 - 1.5 8.8 6.7 0.17 11.9 2.0 1.7 2 0 0 2 2 2 0 Tight junction protein, Claudin-like DUF2516 PF10724.9 GAM38002.1 - 3.4 8.0 8.2 10 6.5 4.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2516) HATPase_c PF02518.26 GAM38003.1 - 1.9e-26 92.8 0.1 6.7e-26 91.0 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM38003.1 - 6.5e-24 84.3 0.6 1.6e-23 83.0 0.5 1.8 2 0 0 2 2 2 1 Response regulator receiver domain PAS_9 PF13426.7 GAM38003.1 - 1.9e-21 76.2 0.0 1.4e-10 41.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain HisKA PF00512.25 GAM38003.1 - 1.6e-18 66.5 0.1 3.7e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 GAM38003.1 - 2.6e-18 66.3 0.0 9.9e-10 38.7 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 GAM38003.1 - 2.8e-17 62.7 0.0 2.1e-09 37.3 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 GAM38003.1 - 4.1e-06 27.0 0.2 0.00085 19.6 0.1 2.5 2 0 0 2 2 2 1 PAS fold NUDIX PF00293.28 GAM38004.1 - 5.4e-15 55.6 1.2 8.3e-15 55.0 1.2 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 GAM38004.1 - 0.0089 16.0 0.2 0.085 12.8 0.2 2.4 1 1 0 1 1 1 1 NUDIX domain Peptidase_M19 PF01244.21 GAM38005.1 - 3.9e-102 341.7 0.0 4.6e-102 341.5 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Radical_SAM PF04055.21 GAM38006.1 - 5.9e-22 78.8 0.2 2e-21 77.1 0.1 2.0 2 1 0 2 2 2 1 Radical SAM superfamily Wyosine_form PF08608.12 GAM38006.1 - 1.2e-14 54.4 0.0 2.7e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 GAM38006.1 - 2.5e-08 34.2 0.1 1.7e-06 28.3 0.1 2.4 1 1 0 1 1 1 1 Flavodoxin DsrH PF04077.12 GAM38006.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 DsrH like protein PhyH PF05721.13 GAM38007.1 - 5e-12 46.5 0.0 9.9e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 GAM38007.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.6 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase adh_short PF00106.25 GAM38008.1 - 2.1e-28 99.2 2.3 5.6e-17 61.8 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM38008.1 - 4.9e-28 98.3 0.1 2.2e-23 83.1 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 GAM38008.1 - 0.016 15.1 0.5 0.023 14.6 0.5 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 GAM38008.1 - 0.038 13.9 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 KR domain MFS_1 PF07690.16 GAM38009.1 - 2.3e-36 125.4 29.5 2.3e-36 125.4 29.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily P-mevalo_kinase PF04275.14 GAM38010.1 - 8.3e-22 77.3 0.0 1.6e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Phosphomevalonate kinase FAD_binding_4 PF01565.23 GAM38010.1 - 1.6e-14 53.9 2.4 1.6e-14 53.9 2.4 1.7 2 0 0 2 2 2 1 FAD binding domain Methyltransf_23 PF13489.6 GAM38010.1 - 0.00011 22.1 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Pribosyltran PF00156.27 GAM38010.1 - 0.0069 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain BBE PF08031.12 GAM38010.1 - 0.0071 16.4 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DPBB_1 PF03330.18 GAM38011.1 - 1.1e-05 25.6 0.0 3.7e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GAM38011.1 - 0.00045 20.2 0.9 0.0011 18.9 0.9 1.7 1 0 0 1 1 1 1 Pollen allergen Barwin PF00967.17 GAM38011.1 - 0.002 18.0 0.5 0.0046 16.8 0.5 1.7 1 0 0 1 1 1 1 Barwin family BNR PF02012.20 GAM38011.1 - 0.14 12.2 1.4 0.77 10.0 0.1 2.6 2 0 0 2 2 2 0 BNR/Asp-box repeat CHB_HEX_C PF03174.13 GAM38011.1 - 0.21 11.6 0.9 0.33 11.0 0.1 1.8 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain SPX PF03105.19 GAM38011.1 - 2 8.2 5.8 2.5 7.9 5.8 1.1 1 0 0 1 1 1 0 SPX domain Smg4_UPF3 PF03467.15 GAM38012.1 - 2.6e-43 148.0 0.0 2.6e-43 148.0 0.0 3.3 3 1 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 GAM38012.1 - 3.8e-09 36.2 0.3 1.3e-07 31.4 0.1 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4440 PF14534.6 GAM38012.1 - 0.013 15.9 0.4 0.046 14.1 0.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) Metallophos PF00149.28 GAM38013.1 - 5.4e-35 121.8 0.0 4.4e-34 118.8 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 GAM38013.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Aldedh PF00171.22 GAM38015.1 - 1.3e-183 610.8 0.1 1.5e-183 610.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UPA_2 PF17809.1 GAM38016.1 - 0.17 11.7 0.2 32 4.4 0.0 3.0 3 0 0 3 3 3 0 UPA domain Glyco_hydro_72 PF03198.14 GAM38017.1 - 6.7e-119 396.8 0.8 9.1e-119 396.4 0.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Mre11_DNA_bind PF04152.14 GAM38018.1 - 7.9e-56 189.0 0.7 7.9e-56 189.0 0.7 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 GAM38018.1 - 3.1e-14 53.9 1.6 5.9e-14 53.1 1.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM38018.1 - 0.0023 18.1 0.1 0.026 14.7 0.1 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Baculo_gp64 PF03273.13 GAM38018.1 - 0.095 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family CHIP_TPR_N PF18391.1 GAM38018.1 - 0.77 10.6 6.4 20 6.0 0.1 2.7 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain F-box-like PF12937.7 GAM38019.1 - 1.5e-10 40.8 0.1 3e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM38019.1 - 7.1e-09 35.3 0.0 2.3e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 GAM38019.1 - 0.021 14.7 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 F-box zf-C2H2_11 PF16622.5 GAM38019.1 - 0.024 14.4 0.4 0.086 12.6 0.1 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 GAM38019.1 - 0.026 15.3 0.1 0.14 13.0 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM38019.1 - 0.059 13.9 0.1 0.19 12.3 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type UIM PF02809.20 GAM38019.1 - 0.26 11.3 2.9 3.3 7.8 0.3 3.1 3 0 0 3 3 3 0 Ubiquitin interaction motif Sugar_tr PF00083.24 GAM38020.1 - 9.8e-84 281.8 28.3 1.2e-83 281.5 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM38020.1 - 5.8e-19 68.2 22.3 5.8e-19 68.2 22.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM38020.1 - 0.00031 19.3 4.7 0.00031 19.3 4.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) LapA_dom PF06305.11 GAM38020.1 - 0.52 10.2 2.4 15 5.5 0.2 3.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF1304 PF06993.12 GAM38020.1 - 5.3 7.1 12.7 0.11 12.5 0.7 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1304) Glyco_hydro_3 PF00933.21 GAM38021.1 - 1e-41 143.4 0.0 1.5e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 GAM38021.1 - 9.4e-15 55.1 0.0 5.5e-11 42.8 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain AA_permease_2 PF13520.6 GAM38022.1 - 5.2e-61 206.7 47.4 6.2e-61 206.5 47.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM38022.1 - 2.5e-13 49.5 41.2 4.5e-13 48.6 41.1 1.4 1 1 0 1 1 1 1 Amino acid permease SieB PF14163.6 GAM38022.1 - 0.43 10.1 3.0 0.85 9.1 0.6 2.7 2 0 0 2 2 2 0 Super-infection exclusion protein B PBP PF01161.20 GAM38023.1 - 8.1e-16 58.5 0.1 1.6e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein LRR_4 PF12799.7 GAM38023.1 - 0.042 14.3 9.0 0.058 13.8 1.1 3.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Tweety PF04906.13 GAM38023.1 - 0.2 10.3 0.0 0.38 9.4 0.0 1.4 2 0 0 2 2 2 0 Tweety LRR_8 PF13855.6 GAM38023.1 - 2.7 7.8 8.0 0.12 12.2 0.3 2.7 4 0 0 4 4 4 0 Leucine rich repeat Glyco_hydro_18 PF00704.28 GAM38024.1 - 1.5e-46 159.6 2.4 3.2e-46 158.5 2.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 GAM38024.1 - 3.1e-10 39.9 0.0 3.5e-06 27.0 0.0 2.8 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 GAM38024.1 - 0.00076 19.9 7.4 0.00076 19.9 7.4 3.8 4 0 0 4 4 4 1 Chitin recognition protein DUF5072 PF16807.5 GAM38024.1 - 0.15 12.1 0.0 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5072) Aa_trans PF01490.18 GAM38025.1 - 2.2e-34 118.9 25.0 3.6e-34 118.2 25.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cdc6_C PF09079.11 GAM38026.1 - 0.085 12.9 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Fur_reg_FbpA PF13076.6 GAM38026.1 - 0.12 12.0 0.9 0.42 10.4 0.0 2.4 2 0 0 2 2 2 0 Fur-regulated basic protein A Glyco_hydro_28 PF00295.17 GAM38027.1 - 1.2e-36 126.4 9.8 2e-36 125.7 9.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 adh_short_C2 PF13561.6 GAM38027.1 - 6.6e-36 124.0 0.4 1.4e-29 103.3 0.1 2.4 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM38027.1 - 2.5e-33 115.2 0.1 4.5e-33 114.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM38027.1 - 1.7e-08 34.6 0.0 4.9e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 KR domain Beta_helix PF13229.6 GAM38027.1 - 0.56 10.0 21.8 0.054 13.3 14.3 2.8 1 1 1 2 2 2 0 Right handed beta helix region Arylsulfotran_2 PF14269.6 GAM38028.1 - 4.2e-38 131.4 0.0 7e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) MAPEG PF01124.18 GAM38028.1 - 2.5e-12 46.8 0.8 4.1e-12 46.1 0.8 1.3 1 0 0 1 1 1 1 MAPEG family Arylsulfotrans PF05935.11 GAM38028.1 - 1.1e-08 34.4 0.1 3.6e-08 32.7 0.0 1.8 3 0 0 3 3 3 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.6 GAM38028.1 - 0.016 14.8 0.5 0.86 9.1 0.0 3.3 4 1 0 5 5 5 0 PQQ-like domain fn3 PF00041.21 GAM38028.1 - 0.082 13.3 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 Fibronectin type III domain Fungal_trans PF04082.18 GAM38029.1 - 2e-06 27.0 0.0 5.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECM1 PF05782.11 GAM38029.1 - 0.31 9.9 4.5 0.42 9.5 4.5 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Hydin_ADK PF17213.3 GAM38029.1 - 0.89 9.8 5.9 6.4 7.0 5.9 2.1 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain Glyco_transf_41 PF13844.6 GAM38030.1 - 1.5e-105 353.4 0.4 5.4e-53 180.1 0.0 3.6 1 1 0 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 GAM38030.1 - 8.4e-17 60.2 12.4 1.2e-05 24.9 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAM38030.1 - 8.7e-14 50.5 13.7 0.0052 16.8 0.1 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM38030.1 - 1.5e-13 50.1 14.6 1.9e-05 24.2 0.2 6.2 3 2 3 6 6 6 4 TPR repeat TPR_8 PF13181.6 GAM38030.1 - 4.6e-11 42.0 5.4 0.087 13.1 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM38030.1 - 1.9e-08 34.1 5.5 0.02 15.2 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM38030.1 - 6.5e-06 26.5 11.3 0.058 14.2 0.0 5.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAM38030.1 - 7.8e-06 25.6 14.6 0.64 10.0 0.2 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAM38030.1 - 6.4e-05 23.5 14.8 0.23 12.2 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM38030.1 - 8e-05 23.1 13.3 0.0034 17.8 0.6 4.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAM38030.1 - 9.1e-05 22.7 12.0 0.76 10.1 1.6 4.9 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAM38030.1 - 0.0017 18.2 9.5 0.54 10.4 0.1 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAM38030.1 - 0.067 12.4 0.2 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 GAM38030.1 - 0.19 12.2 1.7 14 6.1 0.0 3.0 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 GAM38030.1 - 0.37 11.0 7.4 0.36 11.0 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Catalase PF00199.19 GAM38031.1 - 1.5e-172 574.0 0.0 2e-172 573.6 0.0 1.1 1 0 0 1 1 1 1 Catalase Glyco_hydro_47 PF01532.20 GAM38031.1 - 1e-158 529.0 0.0 6.5e-114 381.3 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Catalase-rel PF06628.12 GAM38031.1 - 9.6e-06 25.7 0.1 2.9e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive GMC_oxred_N PF00732.19 GAM38032.1 - 1e-51 176.1 0.0 1.3e-51 175.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM38032.1 - 1.3e-33 116.6 0.0 2e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAM38032.1 - 0.00051 19.2 0.4 0.012 14.7 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 GAM38032.1 - 0.0043 16.3 0.2 0.0096 15.2 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 GAM38032.1 - 0.0048 16.0 0.2 0.0087 15.1 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAM38032.1 - 0.0053 16.0 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM38032.1 - 0.0088 15.7 0.2 0.021 14.4 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM38032.1 - 0.025 13.8 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM38032.1 - 0.029 14.6 0.5 0.081 13.2 0.5 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 GAM38032.1 - 0.19 12.0 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Ribosomal_L11_N PF03946.14 GAM38033.1 - 6.3e-24 83.6 0.2 9.7e-24 83.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 GAM38033.1 - 1.4e-13 51.1 0.1 2.5e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.15 GAM38034.1 - 4.6e-80 268.7 0.0 6.8e-80 268.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 GAM38034.1 - 4.3e-29 101.1 0.0 9.8e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 GAM38034.1 - 3.7e-24 84.5 0.0 8.2e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 GAM38034.1 - 2.5e-14 53.0 4.1 4.5e-14 52.2 4.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAM38034.1 - 7.5e-12 45.0 0.0 3.8e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 GAM38034.1 - 0.019 14.3 1.3 0.029 13.8 0.3 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DNA_primase_lrg PF04104.14 GAM38035.1 - 6.4e-88 294.6 0.0 1e-87 293.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Mito_carr PF00153.27 GAM38036.1 - 2.9e-56 187.4 1.0 2.6e-20 72.2 0.1 4.0 4 0 0 4 4 4 3 Mitochondrial carrier protein SNase PF00565.17 GAM38036.1 - 8.9e-22 77.6 0.0 1.9e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Cutinase PF01083.22 GAM38037.1 - 3.3e-49 167.2 7.8 5.2e-49 166.6 7.8 1.3 1 0 0 1 1 1 1 Cutinase Peptidase_C2 PF00648.21 GAM38037.1 - 2.9e-29 102.0 0.0 4.5e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 GAM38037.1 - 2.9e-06 27.6 0.1 4.4e-05 23.8 0.0 2.8 2 2 0 2 2 2 1 Calpain large subunit, domain III CBM_1 PF00734.18 GAM38037.1 - 2.9e-05 23.9 9.3 2.9e-05 23.9 9.3 2.9 2 1 0 2 2 2 1 Fungal cellulose binding domain PE-PPE PF08237.11 GAM38037.1 - 0.00053 19.6 1.2 0.00086 18.9 0.3 1.7 2 0 0 2 2 2 1 PE-PPE domain MIT PF04212.18 GAM38037.1 - 0.013 15.6 0.2 0.024 14.7 0.2 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF868 PF05910.12 GAM38037.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF868) Vta1 PF04652.16 GAM38038.1 - 5.7e-58 195.0 0.6 5.7e-58 195.0 0.6 1.8 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 GAM38038.1 - 3.7e-17 61.7 0.1 9.5e-17 60.4 0.1 1.8 1 0 0 1 1 1 1 Vta1 C-terminal domain Epimerase PF01370.21 GAM38039.1 - 9.3e-19 67.8 0.0 1.5e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAM38039.1 - 1.2e-10 40.9 0.0 1.7e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 GAM38039.1 - 9.6e-07 28.1 0.0 8.2e-06 25.0 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM38039.1 - 0.0014 18.1 0.0 0.0035 16.8 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 GAM38039.1 - 0.0084 15.6 0.0 0.061 12.8 0.0 2.1 1 1 1 2 2 2 1 short chain dehydrogenase Ldh_1_N PF00056.23 GAM38039.1 - 0.019 15.1 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 GAM38039.1 - 0.026 14.4 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 KR domain Topoisom_I_N PF02919.15 GAM38040.1 - 3.2e-99 330.7 4.6 3.2e-99 330.7 4.6 3.2 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 GAM38040.1 - 6.8e-97 323.3 3.6 6.8e-97 323.3 3.6 2.2 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 GAM38040.1 - 4.5e-34 116.2 1.3 1.7e-33 114.3 1.3 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain Roughex PF06020.11 GAM38040.1 - 0.23 10.5 8.2 0.43 9.6 8.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein ATP-synt PF00231.19 GAM38041.1 - 3.3e-76 256.7 5.4 4e-76 256.4 5.4 1.0 1 0 0 1 1 1 1 ATP synthase Chalcone_2 PF16035.5 GAM38041.1 - 0.083 12.7 0.1 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Chalcone isomerase like F-box-like PF12937.7 GAM38042.1 - 1.7e-07 31.0 0.1 3.8e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM38042.1 - 3.2e-07 30.1 0.1 1.7e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 F-box domain SQHop_cyclase_N PF13249.6 GAM38042.1 - 0.0026 16.9 0.3 0.017 14.3 0.0 1.9 2 0 0 2 2 2 1 Squalene-hopene cyclase N-terminal domain Thioredoxin PF00085.20 GAM38043.1 - 5.5e-34 116.3 0.0 7.6e-27 93.3 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 GAM38043.1 - 6.7e-09 36.2 0.2 0.0039 17.6 0.1 2.5 1 1 1 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 GAM38043.1 - 7.7e-08 32.0 0.0 9.3e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 GAM38043.1 - 0.0028 17.9 0.0 3.3 8.1 0.0 3.5 3 1 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 GAM38043.1 - 0.004 17.1 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_6 PF13848.6 GAM38043.1 - 0.0056 16.6 0.0 0.035 14.0 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAM38043.1 - 0.0094 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 GAM38043.1 - 0.025 14.6 0.0 1.3 9.2 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin domain TraF PF13728.6 GAM38043.1 - 0.11 12.3 0.0 0.11 12.3 0.0 3.8 3 1 1 4 4 3 0 F plasmid transfer operon protein DUF4872 PF16169.5 GAM38043.1 - 0.2 11.4 0.0 0.7 9.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4872) Pap_E4 PF02711.14 GAM38043.1 - 2.5 9.1 6.3 0.99 10.4 2.7 2.1 2 0 0 2 2 2 0 E4 protein GNAT_acetyltr_2 PF13718.6 GAM38044.1 - 1.8e-98 328.5 0.0 3.1e-98 327.7 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 GAM38044.1 - 2.9e-93 311.9 0.0 5.7e-93 310.9 0.0 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 GAM38044.1 - 3.4e-65 219.2 0.0 9.9e-65 217.7 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 GAM38044.1 - 2e-31 107.7 0.5 4.7e-31 106.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 GAM38044.1 - 0.00037 20.3 0.1 0.035 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAM38044.1 - 0.037 14.4 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.25 GAM38044.1 - 0.044 14.0 0.0 0.4 10.9 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family AAA_22 PF13401.6 GAM38044.1 - 0.049 13.9 0.0 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain GHMP_kinases_N PF00288.26 GAM38044.1 - 0.11 12.7 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 GHMP kinases N terminal domain Glyco_hydro_16 PF00722.21 GAM38045.1 - 1e-07 31.6 0.1 6.1e-07 29.1 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Vps8 PF12816.7 GAM38046.1 - 1.3e-57 194.5 0.7 5.3e-57 192.5 0.2 2.1 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 GAM38046.1 - 9.1e-05 22.4 2.1 0.075 12.9 0.1 3.4 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 GAM38046.1 - 0.0032 17.5 0.1 0.0032 17.5 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger Pox_D3 PF04580.13 GAM38046.1 - 0.0067 16.1 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Chordopoxvirinae D3 protein zf-C3HC4_2 PF13923.6 GAM38046.1 - 0.14 12.0 0.6 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM38046.1 - 0.47 10.4 2.3 0.61 10.1 0.4 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Hepatitis_core PF00906.20 GAM38047.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Hepatitis core antigen DEAD PF00270.29 GAM38048.1 - 1.5e-17 63.9 0.0 3.3e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAM38048.1 - 1e-08 35.3 0.0 1.9e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAM38048.1 - 8e-08 32.6 0.1 5.6e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAM38048.1 - 0.0097 16.2 0.0 0.033 14.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM38048.1 - 0.15 12.4 0.4 1.3 9.4 0.2 2.4 2 1 0 2 2 2 0 AAA domain zf-HC5HC2H_2 PF13832.6 GAM38049.1 - 3.7e-21 75.4 0.2 3.7e-21 75.4 0.2 4.5 4 1 0 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GAM38049.1 - 7.1e-19 67.9 0.6 7.1e-19 67.9 0.6 5.0 5 1 0 5 5 5 1 PHD-like zinc-binding domain BAH PF01426.18 GAM38049.1 - 1.2e-16 60.6 0.0 2.4e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 GAM38049.1 - 2.8e-08 33.5 23.7 4e-06 26.6 5.6 5.7 6 0 0 6 6 6 2 PHD-finger PHD_2 PF13831.6 GAM38049.1 - 3.1e-06 26.6 9.1 3.1e-06 26.6 9.1 4.5 6 0 0 6 6 6 1 PHD-finger GATA PF00320.27 GAM38049.1 - 0.0054 16.3 5.0 0.15 11.7 0.9 3.6 2 0 0 2 2 2 1 GATA zinc finger Myb_DNA-binding PF00249.31 GAM38049.1 - 0.059 13.6 0.2 0.14 12.4 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain PDEase_I PF00233.19 GAM38050.1 - 2.3e-70 237.0 0.0 3.4e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase TFIIF_alpha PF05793.12 GAM38050.1 - 0.11 11.0 6.4 0.16 10.5 6.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HD PF01966.22 GAM38050.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 HD domain Rdx PF10262.9 GAM38051.1 - 2.7e-32 110.8 0.0 4.3e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 Rdx family GCD14 PF08704.10 GAM38051.1 - 0.093 12.4 0.3 0.13 12.0 0.3 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Zn_clus PF00172.18 GAM38052.1 - 3.4e-09 36.7 10.7 6.9e-09 35.7 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM38052.1 - 5.7e-09 35.4 2.9 2.2e-08 33.4 0.7 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain DUF3292 PF11696.8 GAM38052.1 - 0.014 13.8 0.3 0.019 13.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) G-gamma PF00631.22 GAM38053.1 - 6.9e-24 83.6 0.0 8e-24 83.4 0.0 1.1 1 0 0 1 1 1 1 GGL domain DUF3220 PF11516.8 GAM38053.1 - 0.18 12.1 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) PCI PF01399.27 GAM38054.1 - 9.6e-12 45.4 0.4 2.4e-10 40.9 0.0 3.0 2 0 0 2 2 2 1 PCI domain DUF4776 PF16003.5 GAM38054.1 - 8.3 5.3 43.6 0.099 11.6 27.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) ATG16 PF08614.11 GAM38055.1 - 0.78 9.9 9.1 0.074 13.3 1.6 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Acetyltransf_1 PF00583.25 GAM38056.1 - 9.7e-09 35.5 0.0 1.4e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM38056.1 - 1.2e-08 34.9 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM38056.1 - 1.3e-06 28.8 0.0 1.9e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM38056.1 - 9.6e-06 25.5 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAM38056.1 - 0.036 14.1 0.1 0.064 13.3 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HlyIII PF03006.20 GAM38057.1 - 1.5e-50 172.0 12.1 2.3e-50 171.4 12.1 1.3 1 0 0 1 1 1 1 Haemolysin-III related Epimerase PF01370.21 GAM38058.1 - 1.4e-14 54.1 0.1 3.1e-14 53.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM38058.1 - 1.3e-12 47.3 0.0 6.3e-12 45.1 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAM38058.1 - 4.4e-10 39.2 0.1 1.1e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 GAM38058.1 - 2.8e-08 33.9 0.4 3.9e-08 33.4 0.4 1.5 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAM38058.1 - 2e-07 30.7 0.3 9.9e-07 28.5 0.3 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAM38058.1 - 6.3e-06 25.9 0.5 2.6e-05 23.9 0.3 1.9 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 GAM38058.1 - 0.00022 20.8 0.0 0.078 12.4 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase Polysacc_synt_2 PF02719.15 GAM38058.1 - 0.054 12.6 0.1 0.11 11.6 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 GAM38059.1 - 1.3e-13 50.6 59.5 1.2e-12 47.4 47.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_3 PF00202.21 GAM38060.1 - 2.6e-13 49.4 0.0 2.4e-11 42.9 0.0 2.7 2 1 0 2 2 2 2 Aminotransferase class-III zf-CCHC PF00098.23 GAM38061.1 - 9.1e-06 25.5 0.6 1.5e-05 24.9 0.6 1.3 1 0 0 1 1 1 1 Zinc knuckle Med19 PF10278.9 GAM38061.1 - 0.00061 19.8 4.9 0.0011 19.0 4.9 1.4 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 TFIIA PF03153.13 GAM38061.1 - 0.0035 17.4 20.3 0.0035 17.4 20.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4820 PF16091.5 GAM38061.1 - 0.0041 16.5 6.6 0.0043 16.4 6.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) Rib PF08428.10 GAM38061.1 - 0.0093 15.9 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 Rib/alpha-like repeat Androgen_recep PF02166.16 GAM38061.1 - 0.01 14.7 21.6 0.012 14.4 21.6 1.1 1 0 0 1 1 1 0 Androgen receptor DDHD PF02862.17 GAM38061.1 - 0.014 15.5 6.2 0.014 15.6 6.2 1.1 1 0 0 1 1 1 0 DDHD domain DUF4407 PF14362.6 GAM38061.1 - 0.015 14.6 14.8 0.019 14.3 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-CCHC_2 PF13696.6 GAM38061.1 - 0.029 14.2 3.3 0.046 13.5 3.3 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4192 PF13830.6 GAM38061.1 - 0.034 14.2 6.1 0.041 14.0 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF913 PF06025.12 GAM38061.1 - 0.035 13.1 5.5 0.04 12.9 5.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 GAM38061.1 - 0.048 12.5 10.4 0.048 12.5 10.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pex14_N PF04695.13 GAM38061.1 - 0.078 13.6 14.5 0.11 13.1 14.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1682 PF07946.14 GAM38061.1 - 0.087 12.0 8.2 0.083 12.1 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Suf PF05843.14 GAM38061.1 - 0.1 12.6 8.4 0.1 12.6 8.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2828 PF11443.8 GAM38061.1 - 0.12 10.4 7.6 0.11 10.5 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3408 PF11888.8 GAM38061.1 - 0.14 12.3 11.6 0.24 11.5 11.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) SpoIIP PF07454.11 GAM38061.1 - 0.16 11.4 13.9 0.19 11.1 13.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pox_Ag35 PF03286.14 GAM38061.1 - 0.18 11.6 12.0 0.3 10.8 12.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Borrelia_P83 PF05262.11 GAM38061.1 - 0.2 10.1 12.7 0.19 10.1 12.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.12 GAM38061.1 - 0.21 11.4 14.2 0.27 11.0 14.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EOS1 PF12326.8 GAM38061.1 - 0.22 11.4 1.5 0.21 11.5 1.5 1.2 1 0 0 1 1 1 0 N-glycosylation protein CPSF100_C PF13299.6 GAM38061.1 - 0.31 11.2 11.3 0.41 10.8 11.3 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SID-1_RNA_chan PF13965.6 GAM38061.1 - 0.55 8.6 3.9 0.54 8.6 3.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 GAM38061.1 - 0.77 9.8 7.5 0.82 9.7 7.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 GAM38061.1 - 1.1 8.1 6.3 1.4 7.8 6.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) MAJIN PF15077.6 GAM38061.1 - 1.5 8.6 8.9 1.9 8.2 8.9 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Presenilin PF01080.17 GAM38061.1 - 1.6 7.4 18.4 2 7.1 18.4 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 GAM38061.1 - 1.7 7.4 10.6 1.9 7.3 10.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 GAM38061.1 - 1.9 7.4 12.9 2.2 7.2 12.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 eIF-3_zeta PF05091.12 GAM38061.1 - 2 7.3 17.1 2.5 7.0 17.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PTPRCAP PF15713.5 GAM38061.1 - 2.9 8.2 23.8 3.8 7.8 23.8 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Band_3_cyto PF07565.13 GAM38061.1 - 4.1 7.1 10.9 5.1 6.8 10.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF1980 PF09323.10 GAM38061.1 - 4.5 7.2 8.1 5.5 6.9 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) LMBR1 PF04791.16 GAM38061.1 - 5.5 5.8 4.3 5.4 5.8 4.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein PBP_sp32 PF07222.12 GAM38061.1 - 5.8 6.3 15.7 7.5 5.9 15.7 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3292 PF11696.8 GAM38061.1 - 6 5.1 12.2 7.6 4.8 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF3306 PF11748.8 GAM38061.1 - 6.8 7.6 20.5 11 6.9 20.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Spt20 PF12090.8 GAM38061.1 - 6.9 6.2 34.8 10 5.7 34.8 1.2 1 0 0 1 1 1 0 Spt20 family Hid1 PF12722.7 GAM38061.1 - 7.5 4.5 14.9 9 4.3 14.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ctr PF04145.15 GAM38061.1 - 8.1 7.1 5.8 11 6.6 5.8 1.4 1 0 0 1 1 1 0 Ctr copper transporter family SprA-related PF12118.8 GAM38061.1 - 8.3 5.4 31.9 10 5.1 31.9 1.1 1 0 0 1 1 1 0 SprA-related family TERB2 PF15101.6 GAM38061.1 - 9.4 6.2 21.0 13 5.8 21.0 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Paf1 PF03985.13 GAM38061.1 - 9.7 5.1 27.3 12 4.7 27.3 1.1 1 0 0 1 1 1 0 Paf1 DUF3578 PF12102.8 GAM38063.1 - 0.044 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3578) RNA_pol_Rpb6 PF01192.22 GAM38064.1 - 1.7e-17 63.0 0.0 3.9e-16 58.7 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb6 DUF1509 PF07420.11 GAM38064.1 - 0.18 10.7 0.8 0.28 10.1 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) zf-C2H2 PF00096.26 GAM38065.1 - 5.5e-29 99.0 55.3 0.00034 20.9 0.1 11.3 10 1 1 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM38065.1 - 1.3e-23 81.6 52.3 0.028 15.2 0.2 10.7 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAM38065.1 - 4.7e-11 42.6 59.5 8.2e-05 22.9 0.3 11.6 13 0 0 13 13 13 6 Zinc-finger double domain FOXP-CC PF16159.5 GAM38065.1 - 2.1e-06 28.3 32.0 0.47 11.1 0.0 9.2 4 2 6 10 10 10 3 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 GAM38065.1 - 0.00025 21.2 26.8 1.1 9.7 0.0 9.1 10 1 0 10 10 10 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 GAM38065.1 - 0.00031 21.0 24.2 0.038 14.3 1.5 4.8 2 1 3 5 5 5 3 C2H2-type zinc ribbon GAGA PF09237.11 GAM38065.1 - 0.00032 20.4 4.2 0.00054 19.7 1.0 2.9 3 0 0 3 3 3 1 GAGA factor zf_Hakai PF18408.1 GAM38065.1 - 0.00083 19.0 12.6 0.16 11.7 2.7 5.9 5 0 0 5 5 5 1 C2H2 Hakai zinc finger domain zf-C2H2_11 PF16622.5 GAM38065.1 - 0.0049 16.6 16.9 0.16 11.7 0.0 5.8 6 0 0 6 6 6 1 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 GAM38065.1 - 0.0074 16.3 0.4 0.068 13.2 0.1 7.8 9 0 0 9 9 9 2 C2H2-type zinc finger Ogr_Delta PF04606.12 GAM38065.1 - 0.026 14.5 8.8 2.7 8.0 0.7 4.1 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-H2C2_5 PF13909.6 GAM38065.1 - 0.041 13.7 36.1 0.16 11.8 1.1 9.5 10 0 0 10 10 10 0 C2H2-type zinc-finger domain zf-met PF12874.7 GAM38065.1 - 0.17 12.3 22.7 4.6 7.8 0.1 8.0 9 0 0 9 9 9 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 GAM38065.1 - 0.67 9.9 12.0 5.2 7.0 0.2 5.2 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) PH PF00169.29 GAM38066.1 - 2.3e-07 31.3 0.0 2.2e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 GAM38066.1 - 0.012 15.9 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain zf-CCHC PF00098.23 GAM38067.1 - 3.7e-05 23.6 0.7 5.4e-05 23.1 0.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 GAM38067.1 - 0.021 14.6 2.8 0.03 14.1 2.8 1.2 1 0 0 1 1 1 0 Zinc knuckle COPIIcoated_ERV PF07970.12 GAM38068.1 - 6.4e-86 287.8 0.1 9.1e-86 287.3 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAM38068.1 - 4e-31 107.2 0.0 3.1e-30 104.4 0.0 2.2 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TAP_C PF03943.13 GAM38069.1 - 6.7e-15 54.5 0.4 1.3e-14 53.5 0.4 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.7 GAM38069.1 - 8.4e-07 29.2 12.0 0.00095 19.5 8.6 2.7 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM38069.1 - 1.6e-06 27.8 4.3 4e-06 26.5 4.3 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 GAM38069.1 - 2.4e-06 27.2 0.1 4.6e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.20 GAM38069.1 - 2.8e-05 24.6 0.0 0.00016 22.2 0.0 2.3 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_9 PF18444.1 GAM38069.1 - 0.00038 20.3 0.0 0.00094 19.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif LRR_6 PF13516.6 GAM38069.1 - 0.024 14.6 4.9 0.031 14.3 0.1 3.0 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 GAM38069.1 - 0.12 13.0 6.6 7 7.6 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat EF-hand_6 PF13405.6 GAM38069.1 - 0.28 11.2 0.9 1.3 9.2 0.9 2.2 1 0 0 1 1 1 0 EF-hand domain Vps53_N PF04100.12 GAM38070.1 - 3.7e-107 358.6 7.4 6.7e-107 357.8 7.4 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 GAM38070.1 - 9.7e-09 34.9 8.0 9.7e-09 34.9 8.0 1.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 GAM38070.1 - 1.9e-06 28.0 2.6 1.9e-06 28.0 2.6 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.13 GAM38070.1 - 0.0069 15.0 7.9 0.013 14.1 7.9 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 ApoLp-III PF07464.11 GAM38070.1 - 0.011 15.9 2.7 0.26 11.4 1.5 2.7 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Sigma70_ner PF04546.13 GAM38070.1 - 0.014 15.3 5.0 0.033 14.1 5.0 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region XhlA PF10779.9 GAM38070.1 - 0.016 15.4 1.8 0.082 13.1 1.8 2.3 1 0 0 1 1 1 0 Haemolysin XhlA Spc7 PF08317.11 GAM38070.1 - 0.03 13.2 8.9 0.063 12.2 8.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 GAM38070.1 - 0.082 11.5 3.1 0.16 10.5 3.1 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A LtuB PF17455.2 GAM38070.1 - 0.11 13.1 0.1 0.31 11.7 0.1 1.7 1 0 0 1 1 1 0 Late transcription unit B Baculo_PEP_C PF04513.12 GAM38070.1 - 0.11 12.5 9.1 0.12 12.4 6.6 2.4 2 1 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec8_exocyst PF04048.14 GAM38070.1 - 0.17 11.8 4.9 0.51 10.2 4.9 1.8 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 GAM38070.1 - 0.2 11.7 4.5 1.5 8.9 3.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 GAM38070.1 - 0.34 11.2 5.4 3.3 8.0 0.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Seryl_tRNA_N PF02403.22 GAM38070.1 - 0.41 10.9 4.7 1.8 8.8 4.6 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 GAM38070.1 - 0.42 11.2 8.5 1.5 9.4 8.3 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF1515 PF07439.11 GAM38070.1 - 0.42 10.7 5.0 0.8 9.8 4.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) BLOC1_2 PF10046.9 GAM38070.1 - 0.59 10.5 6.1 1.4 9.3 4.3 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 GAM38070.1 - 0.62 9.1 11.1 0.39 9.8 8.4 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5339 PF17274.2 GAM38070.1 - 0.91 10.4 9.0 4.4 8.2 0.4 3.2 2 1 1 3 3 2 0 Family of unknown function (DUF5339) BRE1 PF08647.11 GAM38070.1 - 1 9.5 9.4 0.4 10.8 4.6 2.7 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Allexi_40kDa PF05549.11 GAM38070.1 - 1.1 8.8 5.0 1.4 8.4 3.7 1.8 1 1 0 1 1 1 0 Allexivirus 40kDa protein Syntaxin_2 PF14523.6 GAM38070.1 - 1.5 9.2 7.8 4.7 7.6 5.0 3.3 2 1 0 2 2 2 0 Syntaxin-like protein Fib_alpha PF08702.10 GAM38070.1 - 1.5 9.0 7.4 20 5.4 0.8 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 GAM38070.1 - 1.9 9.2 10.2 1.7 9.3 7.3 2.5 2 0 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_MLP1_2 PF07926.12 GAM38070.1 - 2.5 8.2 12.4 0.56 10.3 7.3 2.6 2 1 0 2 2 1 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 GAM38070.1 - 4.7 7.9 5.6 3.9 8.1 1.9 2.7 1 1 1 2 2 2 0 Initiation control protein YabA Epimerase PF01370.21 GAM38071.1 - 7.8e-14 51.7 0.1 1.6e-12 47.4 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAM38071.1 - 3e-07 30.2 0.1 7.1e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 GAM38071.1 - 1.9e-06 27.1 0.0 4e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM38071.1 - 5.1e-06 26.1 0.1 0.036 13.5 0.1 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAM38071.1 - 1.7e-05 24.8 0.2 2.6e-05 24.2 0.2 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 GAM38071.1 - 0.00099 19.5 0.1 0.32 11.5 0.1 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 GAM38071.1 - 0.005 16.0 0.1 0.051 12.7 0.0 2.4 2 1 1 3 3 3 1 Male sterility protein FBPase_glpX PF03320.13 GAM38071.1 - 0.02 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Ldh_1_N PF00056.23 GAM38071.1 - 0.046 13.8 0.2 0.089 12.9 0.2 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 GAM38071.1 - 0.072 12.2 0.3 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 GAM38071.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L10 PF00466.20 GAM38073.1 - 3.4e-22 78.5 0.1 7.9e-22 77.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 GAM38073.1 - 8.4e-22 77.0 0.0 1.9e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 GAM38073.1 - 1.1e-18 67.6 4.8 1.1e-18 67.6 4.8 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein Holin_SPP1 PF04688.13 GAM38073.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 SPP1 phage holin WD40 PF00400.32 GAM38074.1 - 0.00062 20.5 1.3 0.11 13.4 0.1 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat URO-D PF01208.17 GAM38075.1 - 2.6e-128 428.0 0.0 2.9e-128 427.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) dCMP_cyt_deam_1 PF00383.23 GAM38076.1 - 3.6e-22 78.2 0.0 5e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAM38076.1 - 4.7e-19 68.5 0.0 5.6e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 GAM38076.1 - 0.00038 20.5 0.5 0.085 12.9 0.9 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase SNAD4 PF18750.1 GAM38076.1 - 0.0038 17.3 0.0 0.028 14.5 0.0 2.0 2 1 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 GAM38076.1 - 0.0099 15.9 0.1 0.19 11.8 0.1 2.0 1 1 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 GAM38076.1 - 0.019 15.0 0.2 0.2 11.7 0.2 2.0 1 1 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 GAM38076.1 - 0.029 14.3 0.1 0.26 11.2 0.1 1.9 1 1 0 1 1 1 0 APOBEC-like N-terminal domain NAD2 PF18782.1 GAM38076.1 - 0.043 13.9 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 Novel AID APOBEC clade 2 DnaJ_C PF01556.18 GAM38077.1 - 2.7e-39 134.6 0.1 3.5e-39 134.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAM38077.1 - 1.3e-25 89.3 1.7 2.1e-25 88.6 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAM38077.1 - 1.2e-15 57.6 18.9 2.2e-15 56.8 18.9 1.4 1 0 0 1 1 1 1 DnaJ central domain DUF2614 PF11023.8 GAM38077.1 - 0.13 12.4 5.9 1.1 9.4 1.0 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF1356 PF07092.12 GAM38077.1 - 0.14 11.4 2.9 1.4 8.1 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1356) HypA PF01155.19 GAM38077.1 - 1.1 9.3 10.0 0.75 9.8 2.5 2.4 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 GAM38077.1 - 1.4 8.9 17.7 0.15 12.1 2.7 2.9 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 GAM38077.1 - 1.8 8.6 8.1 2.3 8.3 2.1 2.2 1 1 1 2 2 2 0 zinc-ribbons Sulfate_transp PF00916.20 GAM38078.1 - 1.3e-108 363.2 17.4 1.7e-108 362.8 17.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAM38078.1 - 3.7e-08 33.0 0.0 8.2e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAM38078.1 - 0.0011 19.3 2.2 0.0011 19.3 2.2 3.2 3 1 0 3 3 3 2 Molybdate transporter of MFS superfamily Wzy_C PF04932.15 GAM38078.1 - 7.1 6.2 9.3 1.6 8.3 1.1 2.9 3 0 0 3 3 3 0 O-Antigen ligase RTA1 PF04479.13 GAM38079.1 - 3.4e-57 193.4 12.9 3.4e-57 193.4 12.9 2.0 2 0 0 2 2 2 1 RTA1 like protein DUF3430 PF11912.8 GAM38079.1 - 0.029 14.4 0.4 0.071 13.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Rab5ip PF07019.12 GAM38081.1 - 1.3e-22 80.2 2.7 1.8e-22 79.7 2.7 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) BPL_C PF02237.17 GAM38081.1 - 0.08 12.9 0.6 0.16 11.9 0.6 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain SAM_2 PF07647.17 GAM38082.1 - 2e-07 31.0 0.1 5.2e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAM38082.1 - 0.00053 20.4 0.4 0.0033 17.8 0.2 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 GAM38082.1 - 0.095 13.0 0.2 0.24 11.7 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) DHC_N1 PF08385.12 GAM38082.1 - 0.3 9.7 3.5 0.58 8.7 3.5 1.5 1 1 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 TPR_19 PF14559.6 GAM38083.1 - 1.6e-19 70.2 13.7 7.4e-07 29.6 0.0 8.5 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAM38083.1 - 1.3e-16 59.8 25.4 0.0017 19.0 0.5 11.3 11 1 1 12 12 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAM38083.1 - 2.6e-13 49.0 34.7 0.0023 17.9 0.1 10.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAM38083.1 - 2e-12 47.2 17.8 0.00046 20.4 0.1 7.5 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAM38083.1 - 5.9e-12 44.7 17.1 0.003 17.5 0.1 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM38083.1 - 1.4e-11 44.8 18.5 9.5e-07 29.4 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM38083.1 - 2.5e-11 42.9 19.8 0.00044 20.2 0.0 8.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAM38083.1 - 5.1e-11 41.9 27.6 0.00014 21.5 0.1 8.7 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAM38083.1 - 8.2e-10 38.2 10.0 0.021 14.5 0.0 6.8 6 2 2 8 8 8 3 TPR repeat ANAPC3 PF12895.7 GAM38083.1 - 3.4e-07 30.4 16.9 0.011 16.0 0.9 6.5 7 1 0 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GAM38083.1 - 1.8e-06 27.9 18.4 0.041 14.3 0.1 8.3 11 0 0 11 11 7 2 Tetratricopeptide repeat RPN7 PF10602.9 GAM38083.1 - 0.0004 20.1 9.3 0.073 12.8 1.5 4.6 3 1 2 5 5 5 1 26S proteasome subunit RPN7 TPR_9 PF13371.6 GAM38083.1 - 0.00046 20.3 7.7 0.31 11.2 0.0 5.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM38083.1 - 0.00047 20.6 15.9 5.6 7.8 0.2 7.9 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 GAM38083.1 - 0.0014 18.9 1.4 31 5.0 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 GAM38083.1 - 0.0024 18.3 2.1 0.043 14.3 0.2 3.5 3 0 0 3 3 3 1 Bacterial transcriptional activator domain ChAPs PF09295.10 GAM38083.1 - 0.0099 14.9 0.0 0.15 11.0 0.0 2.3 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 GAM38083.1 - 0.016 15.8 13.7 52 4.9 0.0 8.5 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM38083.1 - 0.019 14.8 20.9 1.5 8.8 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 GAM38083.1 - 0.024 15.1 1.0 1.2 9.5 0.0 3.3 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation ANAPC5 PF12862.7 GAM38083.1 - 0.15 12.2 0.6 8.2 6.6 0.0 3.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 DUF5113 PF17140.4 GAM38083.1 - 0.2 11.4 6.5 1.5 8.6 1.2 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5113) TPR_MalT PF17874.1 GAM38083.1 - 2.2 7.6 9.5 33 3.7 0.2 4.9 6 1 1 7 7 7 0 MalT-like TPR region MFS_1 PF07690.16 GAM38084.1 - 1.6e-26 93.1 49.5 3.8e-19 68.8 27.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily E7R PF17467.2 GAM38084.1 - 0.15 12.2 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 Viral Protein E7 CH PF00307.31 GAM38085.1 - 4.1e-08 33.4 0.1 4.8e-05 23.5 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain MMADHC PF10229.9 GAM38085.1 - 2.4 7.8 5.5 0.24 11.1 0.7 1.7 2 0 0 2 2 2 0 Methylmalonic aciduria and homocystinuria type D protein Vezatin PF12632.7 GAM38086.1 - 3.4e-66 223.5 0.2 6e-66 222.7 0.0 1.5 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes PLDc_N PF13396.6 GAM38086.1 - 0.0027 17.6 1.0 0.0049 16.8 1.0 1.4 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal FAA_hydrolase PF01557.18 GAM38087.1 - 6.4e-63 212.3 0.0 1.1e-62 211.6 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.18 GAM38089.1 - 2e-28 99.2 0.1 3.5e-28 98.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_28 PF00295.17 GAM38089.1 - 2.5e-28 99.1 1.9 3.7e-28 98.5 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 GAM38089.1 - 2.6e-06 27.5 10.5 0.00065 19.6 10.4 3.5 1 1 0 1 1 1 1 Pectate lyase superfamily protein Luciferase_cat PF10285.9 GAM38089.1 - 0.035 13.5 0.1 0.061 12.7 0.1 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain Fn3-like PF14310.6 GAM38090.1 - 2.5e-18 65.9 0.0 4.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 GAM38090.1 - 2.1e-14 54.0 0.1 1.7e-12 47.8 0.0 2.5 2 1 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3_C PF01915.22 GAM38091.1 - 4.1e-13 49.7 0.0 6.1e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAM38091.1 - 3.2e-06 26.8 0.0 5.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Lar_N PF09861.9 GAM38091.1 - 0.17 11.1 0.0 0.57 9.3 0.0 1.7 2 0 0 2 2 2 0 Lactate racemase N-terminal domain Cupin_2 PF07883.11 GAM38092.1 - 1.3e-21 76.1 0.1 3.2e-18 65.2 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 GAM38092.1 - 0.0023 17.5 0.0 0.097 12.3 0.0 2.3 2 0 0 2 2 2 1 Cupin Cupin_3 PF05899.12 GAM38092.1 - 0.0032 17.1 0.5 0.042 13.6 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 GAM38092.1 - 0.01 15.7 0.1 0.026 14.4 0.1 1.6 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF2457 PF10446.9 GAM38093.1 - 1.3e-152 509.2 26.5 1.3e-152 509.2 26.5 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) Arf PF00025.21 GAM38094.1 - 1.6e-64 216.6 0.0 1.8e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 GAM38094.1 - 4.6e-10 39.2 0.0 1.9e-06 27.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 GAM38094.1 - 5.2e-08 32.5 0.0 6.4e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 GAM38094.1 - 3.8e-07 30.3 0.0 1.2e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAM38094.1 - 4.8e-07 29.8 0.0 6.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 GAM38094.1 - 7.3e-06 25.7 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAM38094.1 - 0.00013 21.5 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAM38094.1 - 0.081 12.4 0.0 2.3 7.7 0.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain cobW PF02492.19 GAM38094.1 - 0.17 11.4 0.0 9.7 5.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Metallophos PF00149.28 GAM38095.1 - 3.9e-40 138.5 0.1 5.2e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAM38095.1 - 1.1e-22 80.1 2.6 1.5e-22 79.8 1.7 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain LRR_8 PF13855.6 GAM38096.1 - 3.5e-13 49.1 17.7 3.4e-07 29.9 1.3 4.7 3 1 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 GAM38096.1 - 4.4e-13 49.2 9.8 0.0011 19.4 0.0 4.6 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM38096.1 - 7.5e-06 25.8 9.6 4.1 8.3 0.1 7.0 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 GAM38096.1 - 7.5e-05 22.3 0.5 0.0042 16.6 0.7 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 GAM38096.1 - 0.066 13.3 17.3 0.94 9.7 0.5 6.0 6 0 0 6 6 6 0 Leucine Rich repeat DUF3336 PF11815.8 GAM38097.1 - 5.5e-50 168.7 3.6 8.5e-50 168.1 3.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAM38097.1 - 9.1e-19 68.4 0.0 5.7e-18 65.8 0.0 2.3 2 1 1 3 3 3 1 Patatin-like phospholipase DUF1690 PF07956.11 GAM38097.1 - 0.085 13.3 0.7 0.17 12.3 0.7 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) GHMP_kinases_C PF08544.13 GAM38097.1 - 0.21 12.0 0.0 1 9.8 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal Aldo_ket_red PF00248.21 GAM38098.1 - 2.6e-70 237.0 0.0 2.9e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_ABA_S PF18066.1 GAM38098.1 - 0.077 13.7 0.2 0.3 11.8 0.0 2.1 2 1 0 2 2 2 0 Phage ABA sandwich domain Ank_2 PF12796.7 GAM38099.1 - 1.8e-74 246.4 12.1 1.9e-12 47.6 0.0 7.1 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM38099.1 - 3.6e-67 221.9 10.3 4.2e-12 46.3 0.1 8.7 7 1 1 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 GAM38099.1 - 6.8e-54 178.1 17.4 6.9e-05 23.1 0.0 13.6 13 0 0 13 13 13 10 Ankyrin repeat Ank_3 PF13606.6 GAM38099.1 - 4.1e-53 171.1 10.2 0.00036 20.7 0.0 13.6 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 GAM38099.1 - 2.7e-50 167.8 23.2 1e-08 35.3 0.5 11.8 2 2 9 12 12 12 12 Ankyrin repeats (many copies) DUF1612 PF07756.12 GAM38099.1 - 0.015 15.5 0.1 0.075 13.3 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) PCNA_N PF00705.18 GAM38100.1 - 3.5e-52 175.4 2.9 7.1e-52 174.4 2.9 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 GAM38100.1 - 2.2e-47 160.4 0.1 5.8e-47 159.1 0.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Dioxygenase_C PF00775.21 GAM38100.1 - 3.5e-11 42.9 0.4 1.1e-10 41.2 0.2 1.9 2 0 0 2 2 2 1 Dioxygenase Rad9 PF04139.13 GAM38100.1 - 4.2e-06 26.4 0.2 6.6e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 GAM38100.1 - 0.00012 21.2 0.4 0.0057 15.7 0.4 2.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 GAM38100.1 - 0.018 14.2 0.2 0.062 12.4 0.1 1.8 1 1 1 2 2 2 0 Hus1-like protein Fungal_trans PF04082.18 GAM38101.1 - 2e-31 109.0 1.7 3.1e-31 108.4 1.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyclase PF04199.13 GAM38102.1 - 3.2e-17 63.0 0.0 4.4e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Fil_haemagg PF05594.14 GAM38102.1 - 0.036 14.6 0.2 0.064 13.8 0.2 1.4 1 0 0 1 1 1 0 Haemagluttinin repeat Aldo_ket_red PF00248.21 GAM38103.1 - 1.1e-45 156.1 0.0 7.5e-45 153.4 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Cytochrome_P460 PF16694.5 GAM38103.1 - 0.031 14.6 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Cytochrome P460 NAD_binding_4 PF07993.12 GAM38104.1 - 4.9e-44 150.4 0.1 9e-44 149.6 0.1 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAM38104.1 - 1.2e-29 103.2 0.0 2.3e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAM38104.1 - 7.2e-12 45.3 0.1 3.7e-11 42.9 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family SKI PF01202.22 GAM38104.1 - 1.3e-08 35.1 0.0 3.2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 GAM38104.1 - 2.2e-08 34.4 0.1 1.3e-07 31.9 0.0 2.4 3 0 0 3 3 2 1 AAA domain PP-binding PF00550.25 GAM38104.1 - 5.9e-08 32.9 0.3 1.9e-07 31.3 0.3 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site APS_kinase PF01583.20 GAM38104.1 - 1.3e-05 25.1 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase KR PF08659.10 GAM38104.1 - 1.7e-05 24.8 0.3 0.00013 21.9 0.0 2.5 3 0 0 3 3 3 1 KR domain AAA_18 PF13238.6 GAM38104.1 - 1.9e-05 25.2 0.0 0.00012 22.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAM38104.1 - 2e-05 25.0 0.0 7.1e-05 23.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_PrkA PF08298.11 GAM38104.1 - 0.00079 18.4 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain GDP_Man_Dehyd PF16363.5 GAM38104.1 - 0.001 18.5 0.1 0.0017 17.8 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Cytidylate_kin PF02224.18 GAM38104.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 GAM38104.1 - 0.0014 18.8 0.0 0.0036 17.4 0.0 1.7 1 0 0 1 1 1 1 Cytidylate kinase-like family CoaE PF01121.20 GAM38104.1 - 0.0054 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_29 PF13555.6 GAM38104.1 - 0.0084 15.8 0.2 0.085 12.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 GAM38104.1 - 0.0091 15.8 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Polysacc_synt_2 PF02719.15 GAM38104.1 - 0.02 14.0 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 GAM38104.1 - 0.041 12.9 0.0 0.11 11.4 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CP_ATPgrasp_2 PF14403.6 GAM38104.1 - 0.044 12.7 0.0 0.087 11.7 0.0 1.4 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 Rad17 PF03215.15 GAM38104.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 GAM38104.1 - 0.092 13.0 0.0 0.38 11.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain Semialdhyde_dh PF01118.24 GAM38104.1 - 0.092 13.2 0.0 0.37 11.2 0.0 2.1 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAM38104.1 - 0.14 12.2 0.0 0.44 10.7 0.0 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus T2SS-T3SS_pil_N PF13629.6 GAM38104.1 - 0.15 11.8 0.5 0.84 9.4 0.0 2.3 2 0 0 2 2 2 0 Pilus formation protein N terminal region MFS_1 PF07690.16 GAM38105.1 - 3.7e-35 121.5 30.9 5.8e-35 120.9 30.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM38105.1 - 0.00091 18.6 16.6 0.0064 15.8 4.5 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF1360 PF07098.11 GAM38105.1 - 0.21 11.6 2.3 0.58 10.1 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1360) MFS_1 PF07690.16 GAM38106.1 - 1.2e-32 113.2 21.8 1.2e-32 113.2 21.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily H_kinase_N PF12282.8 GAM38107.1 - 0.071 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Signal transduction histidine kinase Sec61_beta PF03911.16 GAM38108.1 - 1.6e-17 63.2 0.8 2.2e-17 62.8 0.8 1.2 1 0 0 1 1 1 1 Sec61beta family SSF PF00474.17 GAM38109.1 - 1.7e-15 56.8 34.2 2.8e-15 56.1 34.2 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF5310 PF17237.2 GAM38109.1 - 0.038 13.9 0.2 0.13 12.1 0.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5310) RRM_1 PF00076.22 GAM38110.1 - 4.6e-72 237.8 2.7 2.2e-18 65.8 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM38110.1 - 5.5e-06 26.1 0.0 0.069 13.0 0.0 4.3 5 0 0 5 5 5 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 GAM38110.1 - 1.3e-05 25.2 0.3 3.5 7.8 0.0 5.3 5 0 0 5 5 5 1 Limkain b1 Nup35_RRM_2 PF14605.6 GAM38110.1 - 2.1e-05 24.4 0.1 1.1 9.4 0.0 4.5 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 GAM38110.1 - 0.00039 20.0 0.0 0.012 15.2 0.0 3.1 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM38110.1 - 0.0015 18.7 0.0 27 5.0 0.0 4.1 3 0 0 3 3 3 0 RNA recognition motif RRM_2 PF04059.12 GAM38110.1 - 0.05 13.8 0.0 4.6 7.5 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif 2 MRP-S24 PF14955.6 GAM38110.1 - 0.06 13.3 0.6 4.1 7.4 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S24 TEA PF01285.18 GAM38111.1 - 6.6e-27 93.4 0.0 1.5e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain Aldo_ket_red PF00248.21 GAM38112.1 - 2e-43 148.7 0.0 2.5e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Parvo_coat_N PF08398.10 GAM38113.1 - 0.025 14.7 0.6 0.092 12.9 0.2 2.0 1 1 1 2 2 2 0 Parvovirus coat protein VP1 LRR_4 PF12799.7 GAM38114.1 - 3.6e-35 119.4 38.5 5.3e-09 36.2 6.0 7.1 3 2 7 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM38114.1 - 4e-21 74.5 38.0 5.9e-06 25.9 6.7 6.3 2 2 2 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 GAM38114.1 - 2.1e-14 53.4 17.5 1.2e-05 24.9 3.4 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 GAM38114.1 - 4.9e-05 23.3 26.7 5.8 7.9 0.2 8.7 8 2 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 GAM38114.1 - 0.0013 18.6 26.2 2.6 8.3 0.7 7.9 7 0 0 7 7 7 3 Leucine Rich repeat NIF PF03031.18 GAM38115.1 - 4.3e-54 182.5 0.1 6.4e-54 182.0 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABC_membrane_2 PF06472.15 GAM38116.1 - 4.1e-88 295.3 0.5 8e-88 294.3 0.1 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GAM38116.1 - 4.2e-15 56.5 0.0 8e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 GAM38116.1 - 0.0012 19.3 0.1 0.14 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAM38116.1 - 0.0093 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 GAM38116.1 - 0.047 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 GAM38116.1 - 0.098 12.4 0.0 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 GAM38116.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAM38116.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 GAM38116.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAM38116.1 - 0.15 12.3 0.1 0.58 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Acyl_transf_3 PF01757.22 GAM38117.1 - 1.6e-20 73.5 38.6 1.2e-19 70.6 38.6 2.2 1 1 0 1 1 1 1 Acyltransferase family Clr2 PF10383.9 GAM38118.1 - 1.1e-31 110.6 0.2 2.9e-31 109.2 0.0 1.9 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 CNDH2_M PF16869.5 GAM38118.1 - 0.64 10.7 5.3 4.1 8.1 6.1 1.9 2 0 0 2 2 2 0 PF16858 2OG-FeII_Oxy PF03171.20 GAM38119.1 - 0.00024 21.5 0.0 0.0012 19.3 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 GAM38119.1 - 0.0013 19.5 0.0 0.0025 18.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal tRNA-synt_2 PF00152.20 GAM38120.1 - 3.4e-74 249.8 0.0 4e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 GAM38120.1 - 5.2e-06 26.1 0.4 0.0037 16.8 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 GAM38120.1 - 0.0017 18.3 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain zf-Tim10_DDP PF02953.15 GAM38121.1 - 4.2e-22 77.6 0.5 5.1e-22 77.3 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DHC_N1 PF08385.12 GAM38122.1 - 0.0061 15.3 0.3 0.0089 14.7 0.3 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 NPV_P10 PF05531.12 GAM38122.1 - 0.054 14.0 0.5 4.6 7.8 0.0 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 GAM38122.1 - 0.061 13.7 0.5 0.21 12.0 0.5 1.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PG_binding_1 PF01471.18 GAM38122.1 - 0.095 12.9 0.4 17 5.7 0.0 3.7 4 1 0 4 4 4 0 Putative peptidoglycan binding domain Seryl_tRNA_N PF02403.22 GAM38122.1 - 0.1 12.8 0.2 0.42 10.9 0.1 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CLTH PF10607.9 GAM38123.1 - 1.4e-32 112.7 0.0 2.5e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 GAM38123.1 - 1.1e-08 35.0 0.4 2.3e-08 33.9 0.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 GAM38123.1 - 0.0003 20.3 0.2 0.0003 20.3 0.2 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_5 PF14634.6 GAM38123.1 - 0.00067 19.6 0.4 0.0011 18.8 0.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAM38123.1 - 0.001 19.3 0.7 0.0018 18.5 0.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM38123.1 - 0.0021 17.8 1.5 0.0045 16.8 1.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM38123.1 - 0.0068 16.2 1.3 0.013 15.4 1.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 GAM38123.1 - 0.0095 15.8 1.2 0.018 14.9 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM38123.1 - 0.014 15.2 0.6 0.025 14.4 0.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAM38123.1 - 0.094 12.9 1.2 0.2 11.9 1.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING BTB PF00651.31 GAM38124.1 - 3.7e-07 30.4 0.0 1.6e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain PCI PF01399.27 GAM38125.1 - 1.1e-08 35.6 0.0 2.3e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain Cohesin_load PF10345.9 GAM38125.1 - 0.059 11.8 0.0 0.095 11.1 0.0 1.3 1 0 0 1 1 1 0 Cohesin loading factor TPR_2 PF07719.17 GAM38125.1 - 0.13 12.5 0.1 0.42 10.8 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_L18A PF01775.17 GAM38126.1 - 3.1e-55 185.4 0.2 3.9e-55 185.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A NAD_binding_1 PF00175.21 GAM38127.1 - 3e-35 121.2 0.0 5e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAM38127.1 - 3.3e-23 81.9 0.0 8.7e-23 80.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAM38127.1 - 5.2e-10 39.6 0.0 4.3e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain HMG_box PF00505.19 GAM38128.1 - 5.5e-11 42.7 0.9 1.2e-10 41.7 0.9 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAM38128.1 - 5.1e-06 27.0 0.4 1.3e-05 25.7 0.4 1.8 1 0 0 1 1 1 1 HMG-box domain TLP-20 PF06088.11 GAM38128.1 - 0.025 14.5 1.4 0.054 13.4 1.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) GEN1_C PF18380.1 GAM38128.1 - 0.56 11.1 13.7 2 9.4 0.0 2.7 2 1 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain NOA36 PF06524.12 GAM38128.1 - 0.88 8.8 5.0 1.7 7.9 5.0 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 GAM38128.1 - 1.1 7.5 8.6 1.6 6.9 8.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Amidohydro_1 PF01979.20 GAM38129.1 - 6.6e-76 255.8 0.7 1e-75 255.2 0.7 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 GAM38129.1 - 2.5e-57 192.4 1.0 5.5e-57 191.3 1.0 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 GAM38129.1 - 1.1e-41 140.8 0.3 6.7e-41 138.3 0.0 2.1 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 GAM38129.1 - 7.4e-30 103.2 0.3 8.7e-29 99.8 0.1 2.6 2 1 0 2 2 2 1 Urease, gamma subunit Amidohydro_3 PF07969.11 GAM38129.1 - 3e-10 40.2 0.1 6.1e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family zf-RING_2 PF13639.6 GAM38130.1 - 6.5e-11 42.4 6.1 1.2e-10 41.5 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAM38130.1 - 8e-10 38.3 3.6 8e-10 38.3 3.6 1.9 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAM38130.1 - 8.6e-07 28.7 5.2 1.6e-06 27.8 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM38130.1 - 2.6e-06 27.2 3.3 4.9e-06 26.3 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM38130.1 - 3.6e-05 23.6 3.9 6.6e-05 22.8 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAM38130.1 - 3.9e-05 23.6 1.9 3.9e-05 23.6 1.9 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAM38130.1 - 0.00018 21.7 5.6 0.00089 19.5 5.6 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAM38130.1 - 0.0013 18.5 3.4 0.0024 17.7 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM38130.1 - 0.0095 15.8 5.7 0.023 14.6 5.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF4381 PF14316.6 GAM38130.1 - 0.017 15.4 0.1 0.017 15.4 0.1 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4381) zf-ANAPC11 PF12861.7 GAM38130.1 - 0.02 14.9 1.4 0.044 13.8 1.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RCR PF12273.8 GAM38130.1 - 0.038 14.6 0.3 4 8.1 0.0 2.5 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Zn_ribbon_17 PF17120.5 GAM38130.1 - 0.055 13.1 3.6 0.11 12.2 3.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 GAM38130.1 - 0.096 13.0 2.3 0.25 11.7 2.3 1.8 1 0 0 1 1 1 0 RING-like domain zf-Nse PF11789.8 GAM38130.1 - 0.23 11.3 2.9 0.56 10.1 2.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 GAM38130.1 - 0.31 11.2 1.0 0.74 10.0 1.0 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_6 PF14835.6 GAM38130.1 - 0.61 10.0 2.2 1.3 9.0 2.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Smim3 PF17307.2 GAM38130.1 - 1.8 8.1 3.6 4.7 6.8 3.6 1.6 1 0 0 1 1 1 0 Small integral membrane protein 3 Ada3 PF10198.9 GAM38131.1 - 1.6e-51 173.9 0.1 1.6e-51 173.9 0.1 2.0 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 NPR2 PF06218.11 GAM38132.1 - 8.7e-117 390.6 1.6 3.9e-68 230.2 0.0 3.4 2 1 1 3 3 3 3 Nitrogen permease regulator 2 MULE PF10551.9 GAM38132.1 - 0.017 15.5 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 MULE transposase domain SinI PF08671.10 GAM38133.1 - 0.025 14.3 3.6 0.47 10.3 2.5 2.7 2 0 0 2 2 2 0 Anti-repressor SinI DUF1656 PF07869.12 GAM38133.1 - 0.21 11.6 0.6 0.45 10.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) MFS_1 PF07690.16 GAM38135.1 - 1.9e-43 148.7 42.3 8e-43 146.7 43.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Bac_export_2 PF01312.19 GAM38135.1 - 1.2 8.3 0.0 1.2 8.3 0.0 2.9 3 0 0 3 3 3 0 FlhB HrpN YscU SpaS Family DRMBL PF07522.14 GAM38136.1 - 4.3e-08 33.3 0.2 1.7e-07 31.4 0.2 2.0 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 GAM38136.1 - 0.01 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain FRG1 PF06229.12 GAM38137.1 - 5.5e-54 182.8 5.5 4.6e-53 179.8 5.5 2.1 1 1 0 1 1 1 1 FRG1-like domain AP2 PF00847.20 GAM38137.1 - 0.026 14.8 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 AP2 domain Fascin PF06268.13 GAM38137.1 - 0.034 14.4 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Fascin domain ADH_N PF08240.12 GAM38138.1 - 1.3e-35 121.6 3.5 3.2e-35 120.3 2.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM38138.1 - 1e-15 57.9 0.0 1.7e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAM38138.1 - 4.1e-13 49.3 0.0 6.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAM38138.1 - 5.4e-07 30.7 0.0 9.8e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 GAM38138.1 - 0.012 14.8 0.5 0.021 14.1 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain NADH_4Fe-4S PF10589.9 GAM38138.1 - 0.1 12.7 0.3 0.33 11.0 0.3 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Sacchrp_dh_NADP PF03435.18 GAM38138.1 - 0.14 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 GAM38139.1 - 0.0005 19.6 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HECT PF00632.25 GAM38141.1 - 7.8e-77 258.8 0.0 1e-76 258.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ITAM_Cys-rich PF10538.9 GAM38141.1 - 0.14 11.9 0.3 0.35 10.7 0.3 1.6 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif Ribosomal_L15e PF00827.17 GAM38142.1 - 6.4e-88 293.5 10.2 7.8e-88 293.2 10.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 PSP1 PF04468.12 GAM38143.1 - 1.2e-27 95.9 2.7 2.5e-27 95.0 2.7 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF4677 PF15726.5 GAM38143.1 - 0.015 15.5 0.2 0.041 14.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) Nfu_N PF08712.11 GAM38144.1 - 4e-30 103.7 0.0 2.1e-29 101.4 0.0 2.1 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 GAM38144.1 - 1.1e-27 95.9 0.1 1.9e-27 95.2 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain RasGEF PF00617.19 GAM38145.1 - 1.2e-42 146.1 0.0 2.3e-42 145.2 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM38145.1 - 1.7e-14 53.9 0.0 4.5e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Complex1_LYR_2 PF13233.6 GAM38146.1 - 3.3e-22 79.0 0.8 4.5e-22 78.6 0.8 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 GAM38146.1 - 4.2e-05 23.5 0.9 7.4e-05 22.7 0.9 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DSBA PF01323.20 GAM38146.1 - 0.0048 16.7 0.1 0.0061 16.3 0.1 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain CHD5 PF04420.14 GAM38146.1 - 0.12 12.2 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 CHD5-like protein ATP_bind_3 PF01171.20 GAM38147.1 - 5.5e-20 71.9 0.0 1e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 GAM38147.1 - 3.4e-19 68.0 15.2 6.5e-19 67.1 3.8 3.7 4 0 0 4 4 4 2 Zinc-ribbon tRNA_Me_trans PF03054.16 GAM38147.1 - 0.018 13.8 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase RecR PF02132.15 GAM38147.1 - 0.024 14.2 0.7 0.024 14.2 0.7 2.6 3 0 0 3 3 3 0 RecR protein zf-UBR PF02207.20 GAM38147.1 - 0.52 10.5 4.8 7 6.9 0.5 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) ERG2_Sigma1R PF04622.12 GAM38149.1 - 5.4e-99 329.7 0.4 6.5e-99 329.5 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Cyclin_N PF00134.23 GAM38150.1 - 2.7e-11 43.3 0.0 7.7e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAM38150.1 - 7.2e-07 29.7 0.0 1.4e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Cyclin DASH_Spc34 PF08657.10 GAM38150.1 - 0.092 12.5 0.6 0.16 11.7 0.6 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 Acetyltransf_8 PF13523.6 GAM38151.1 - 7.7e-43 145.6 0.0 1.1e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain OCD_Mu_crystall PF02423.15 GAM38152.1 - 1.8e-15 56.7 0.0 3.4e-14 52.5 0.0 2.6 2 1 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 GAM38152.1 - 3e-07 30.6 0.0 2.3e-05 24.5 0.0 2.8 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 GAM38152.1 - 0.089 13.4 0.0 0.37 11.4 0.0 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF1992 PF09350.10 GAM38154.1 - 7.9e-24 83.6 0.2 1.9e-23 82.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) ArlS_N PF18719.1 GAM38154.1 - 0.042 14.1 0.1 0.27 11.5 0.0 2.4 3 0 0 3 3 3 0 ArlS sensor domain CmlA_N PF18456.1 GAM38154.1 - 0.092 12.0 0.2 7.9 5.7 0.0 2.5 3 0 0 3 3 3 0 Diiron non-heme beta-hydroxylase N-terminal domain Cmc1 PF08583.10 GAM38155.1 - 0.098 12.7 0.2 0.12 12.4 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like His_Phos_1 PF00300.22 GAM38156.1 - 1.4e-35 122.7 0.0 1.9e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) p450 PF00067.22 GAM38157.1 - 7.3e-47 160.2 0.0 9.5e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 GAM38158.1 - 3.8e-06 26.7 0.1 3.8e-06 26.7 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAM38158.1 - 0.00022 21.0 0.0 0.0005 19.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAM38158.1 - 0.031 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 F-box SRP40_C PF05022.12 GAM38159.1 - 4e-16 59.6 0.4 4e-16 59.6 0.4 2.2 2 0 0 2 2 2 1 SRP40, C-terminal domain Sec3_C PF09763.9 GAM38160.1 - 4.1e-222 739.4 4.3 5.3e-222 739.1 4.3 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 GAM38160.1 - 5.6e-28 96.9 0.2 1.5e-27 95.5 0.2 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 GAM38160.1 - 0.014 15.7 2.9 0.027 14.8 0.1 2.7 3 0 0 3 3 3 0 Sec3 exocyst complex subunit Vps52 PF04129.12 GAM38160.1 - 0.077 11.7 0.5 0.13 11.0 0.5 1.3 1 0 0 1 1 1 0 Vps52 / Sac2 family DOCK_N PF16172.5 GAM38161.1 - 6.2e-97 324.9 0.0 2.5e-94 316.3 0.0 2.3 1 1 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 GAM38161.1 - 3.4e-43 148.1 6.0 6.8e-43 147.1 6.0 1.4 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 GAM38161.1 - 2.1e-38 132.1 0.0 3.9e-38 131.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 GAM38161.1 - 4.4e-05 23.3 0.0 0.00043 20.1 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 GAM38161.1 - 0.00011 21.7 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Phage_AlpA PF05930.12 GAM38161.1 - 0.074 12.9 0.1 6.9 6.6 0.0 2.7 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) Metallophos PF00149.28 GAM38162.1 - 2.6e-12 47.7 1.3 3.8e-12 47.1 1.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM38162.1 - 6.5e-08 32.9 1.2 3.7e-06 27.2 1.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_S8e PF01201.22 GAM38163.1 - 1.1e-41 142.2 1.4 3.4e-41 140.6 1.4 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.6 GAM38163.1 - 0.068 14.1 0.3 0.27 12.2 0.0 1.9 2 0 0 2 2 2 0 Small acidic protein family DUF2470 PF10615.9 GAM38164.1 - 2.7e-20 72.8 0.1 4.2e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) YwhD PF08741.10 GAM38164.1 - 0.21 11.3 0.4 5 6.8 0.2 2.1 2 0 0 2 2 2 0 YwhD family Bim_N PF06773.11 GAM38165.1 - 0.089 12.5 0.3 0.18 11.5 0.3 1.5 1 0 0 1 1 1 0 Bim protein N-terminus PBP1_TM PF14812.6 GAM38165.1 - 2.1 8.8 33.8 0.38 11.1 19.7 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 GAM38165.1 - 5.5 7.4 28.0 0.044 14.2 11.5 2.4 2 1 0 2 2 2 0 Centromere protein B dimerisation domain CCSAP PF15748.5 GAM38166.1 - 0.086 13.0 23.1 0.1 12.7 23.1 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Senescence PF06911.12 GAM38166.1 - 0.81 10.0 0.0 0.81 10.0 0.0 2.4 2 1 0 2 2 2 0 Senescence-associated protein SPX PF03105.19 GAM38167.1 - 8.7e-33 114.8 6.8 8.8e-21 75.3 0.0 3.4 3 1 1 4 4 4 2 SPX domain Ribosomal_S7 PF00177.21 GAM38167.1 - 1e-28 99.9 0.0 2.4e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Na_sulph_symp PF00939.19 GAM38167.1 - 3.9e-27 95.4 44.6 5.8e-27 94.9 44.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 GAM38167.1 - 9.5e-24 84.1 40.8 1.8e-23 83.2 40.8 1.5 1 0 0 1 1 1 1 Citrate transporter Cytochrome-c551 PF10643.9 GAM38167.1 - 0.01 15.4 0.3 0.034 13.7 0.3 1.8 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Na_Ca_ex PF01699.24 GAM38168.1 - 1.2e-41 142.2 40.6 5e-21 75.2 14.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Glyco_hydro81C PF17652.1 GAM38169.1 - 2.6e-165 549.9 7.3 3.2e-165 549.5 7.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 GAM38169.1 - 4.9e-114 380.8 0.3 6.8e-114 380.4 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Utp14 PF04615.13 GAM38170.1 - 1.4e-212 708.4 61.8 1.5e-212 708.3 61.8 1.0 1 0 0 1 1 1 1 Utp14 protein MRP-L27 PF09809.9 GAM38171.1 - 9e-14 51.3 0.1 1.7e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 IQ PF00612.27 GAM38172.1 - 0.0023 17.6 1.1 0.01 15.6 1.1 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF1465 PF07323.12 GAM38172.1 - 0.038 13.8 1.1 0.084 12.7 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) HECT PF00632.25 GAM38173.1 - 2.4e-83 280.1 0.0 2.9e-83 279.9 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RRM_1 PF00076.22 GAM38174.1 - 8e-81 265.9 7.0 2.2e-21 75.4 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GAM38174.1 - 1.8e-29 101.7 0.7 1.2e-28 99.0 0.9 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 GAM38174.1 - 2.5e-15 56.2 0.1 0.0023 17.5 0.0 5.2 2 1 3 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM38174.1 - 9.9e-05 22.4 0.8 7.2 6.8 0.0 5.3 4 2 0 4 4 4 1 RNA recognition motif CbiG_mid PF11761.8 GAM38174.1 - 0.00051 20.1 0.0 3.4 7.9 0.0 3.5 3 0 0 3 3 3 1 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.6 GAM38174.1 - 0.00065 19.7 0.9 16 5.6 0.0 4.5 4 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 GAM38174.1 - 0.025 14.4 0.0 20 5.1 0.0 3.2 3 0 0 3 3 3 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 GAM38174.1 - 0.03 14.4 1.6 25 5.0 0.0 3.6 3 0 0 3 3 3 0 Limkain b1 YflT PF11181.8 GAM38174.1 - 0.086 13.4 8.1 0.14 12.7 1.0 3.0 3 0 0 3 3 2 0 Heat induced stress protein YflT OB_RNB PF08206.11 GAM38174.1 - 0.22 11.2 3.2 15 5.3 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain DUF4834 PF16118.5 GAM38174.1 - 0.62 11.1 5.7 0.21 12.6 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DAO PF01266.24 GAM38175.1 - 1.6e-64 218.7 0.1 1.8e-64 218.6 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM38175.1 - 8e-06 26.0 0.2 1.9e-05 24.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM38175.1 - 0.00061 19.0 0.0 0.00091 18.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM38175.1 - 0.002 17.4 0.1 0.039 13.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAM38175.1 - 0.0083 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAM38175.1 - 0.011 15.0 0.2 0.069 12.4 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 GAM38175.1 - 0.052 12.8 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 GAM38175.1 - 0.067 12.4 0.5 0.29 10.4 0.2 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM38175.1 - 0.079 13.5 0.1 0.64 10.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM38175.1 - 0.11 11.1 0.1 0.24 10.1 0.2 1.4 2 0 0 2 2 2 0 HI0933-like protein Fungal_trans PF04082.18 GAM38176.1 - 9.5e-13 47.8 1.8 4.4e-12 45.6 1.8 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAM38176.1 - 1.8e-06 28.0 14.4 0.008 16.6 2.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM38176.1 - 3.4e-06 27.2 8.8 3.4e-06 27.2 8.8 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAM38176.1 - 3.5e-05 24.3 11.9 0.022 15.6 1.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAM38176.1 - 9.7e-05 22.6 12.1 0.023 15.0 4.2 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAM38176.1 - 0.00024 21.4 12.1 0.033 14.6 1.5 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 GAM38176.1 - 0.05 13.5 7.1 0.24 11.3 1.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PHD_4 PF16866.5 GAM38176.1 - 0.19 11.9 1.2 0.6 10.2 1.2 1.8 1 0 0 1 1 1 0 PHD-finger zf-C2H2_6 PF13912.6 GAM38176.1 - 0.47 10.5 7.2 0.12 12.4 1.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger C1_4 PF07975.12 GAM38176.1 - 1.4 9.2 7.3 7.6 6.9 3.7 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain HNH PF01844.23 GAM38176.1 - 6.3 7.1 6.2 35 4.7 0.3 2.6 2 0 0 2 2 2 0 HNH endonuclease HgmA PF04209.13 GAM38177.1 - 2.1e-138 461.6 0.1 2.4e-138 461.4 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Thiolase_N PF00108.23 GAM38178.1 - 7.5e-74 248.4 0.1 1.2e-73 247.7 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lyase_1 PF00206.20 GAM38178.1 - 4.2e-47 161.1 0.0 1.6e-46 159.2 0.0 1.9 2 0 0 2 2 2 1 Lyase Thiolase_C PF02803.18 GAM38178.1 - 1.3e-38 131.4 0.0 2.9e-38 130.3 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ADSL_C PF10397.9 GAM38178.1 - 7e-22 77.8 0.0 3.2e-20 72.4 0.0 2.8 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus ketoacyl-synt PF00109.26 GAM38178.1 - 0.016 14.8 0.2 0.045 13.3 0.2 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain CoA_trans PF01144.23 GAM38179.1 - 2.5e-91 304.9 0.5 8.3e-55 185.5 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF4113 PF13438.6 GAM38180.1 - 0.0018 18.3 0.0 0.0037 17.3 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4113) Agarase_CBM PF17992.1 GAM38180.1 - 0.063 12.8 0.0 0.072 12.6 0.0 1.1 1 0 0 1 1 1 0 Agarase CBM like domain CoA_transf_3 PF02515.17 GAM38181.1 - 1.1e-109 367.0 0.0 1.4e-109 366.6 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III FAD-oxidase_C PF02913.19 GAM38181.1 - 2e-15 57.1 0.0 3.3e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAM38181.1 - 8.9e-15 54.6 0.1 1.7e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain eIF-5a PF01287.20 GAM38182.1 - 1.7e-28 98.5 1.5 2.4e-28 98.0 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 GAM38182.1 - 0.0052 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain ubiquitin PF00240.23 GAM38183.1 - 7.8e-33 112.1 0.6 1.9e-32 110.8 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 GAM38183.1 - 8.5e-30 102.4 11.4 1.6e-29 101.5 11.4 1.5 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 GAM38183.1 - 2.1e-14 53.1 0.6 6.6e-14 51.5 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like zf-RRN7 PF11781.8 GAM38183.1 - 3e-08 33.2 5.2 3e-08 33.2 5.2 2.0 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ubiquitin_2 PF14560.6 GAM38183.1 - 0.00045 20.6 0.1 0.0014 19.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAM38183.1 - 0.033 14.1 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GAM38183.1 - 0.033 14.5 0.0 0.075 13.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAM38183.1 - 0.077 13.1 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Yip1 PF04893.17 GAM38184.1 - 3.4e-14 52.9 14.9 5.4e-14 52.3 14.9 1.4 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 GAM38184.1 - 0.045 13.3 2.1 0.07 12.6 1.6 1.6 1 1 0 1 1 1 0 YIF1 RabGAP-TBC PF00566.18 GAM38185.1 - 1.2e-11 44.7 0.3 2.3e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 GAM38187.1 - 3.1e-10 40.5 0.0 4.7e-05 23.9 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM38187.1 - 1.3e-07 31.7 0.8 4.4e-05 23.7 0.0 4.2 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 GAM38187.1 - 4.7e-06 26.8 1.4 1.6 9.3 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 GAM38187.1 - 4.7e-05 23.5 0.2 8.1 7.4 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 GAM38187.1 - 0.00044 20.7 5.9 0.39 11.4 0.0 5.1 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Aldedh PF00171.22 GAM38188.1 - 1.1e-142 475.9 0.0 1.2e-141 472.4 0.0 2.0 2 0 0 2 2 2 1 Aldehyde dehydrogenase family Peptidase_M20 PF01546.28 GAM38188.1 - 1.1e-19 71.0 0.1 2.4e-19 69.8 0.1 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM38188.1 - 6.8e-06 26.0 0.1 2.2e-05 24.3 0.1 2.0 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAM38188.1 - 0.00037 20.3 0.0 0.00073 19.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 FAD_binding_3 PF01494.19 GAM38189.1 - 1.5e-63 215.2 0.0 1.8e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAM38189.1 - 8e-07 29.2 0.0 1.8e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 GAM38189.1 - 4.1e-05 23.3 0.0 0.00011 21.9 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM38189.1 - 0.00058 19.2 0.0 0.0034 16.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM38189.1 - 0.0012 18.2 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 GAM38189.1 - 0.0043 16.3 0.0 0.012 14.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM38189.1 - 0.0049 15.8 0.0 0.011 14.7 0.0 1.6 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 GAM38189.1 - 0.014 15.9 0.1 0.16 12.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM38189.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 GAM38189.1 - 0.039 12.6 0.0 0.067 11.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 GAM38189.1 - 0.043 14.1 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM38189.1 - 0.078 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N PF00107.26 GAM38190.1 - 0.00063 19.7 0.2 0.00094 19.2 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Putative_G5P PF17426.2 GAM38190.1 - 0.13 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative Gamma DNA binding protein G5P Transp_cyt_pur PF02133.15 GAM38191.1 - 5.7e-37 127.5 35.7 7.3e-37 127.2 35.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MMS1_N PF10433.9 GAM38192.1 - 2e-68 231.2 0.0 2.4e-49 168.3 0.0 2.7 1 1 2 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GAM38192.1 - 1.2e-07 31.4 0.0 2.8e-06 26.9 0.0 2.8 3 1 0 3 3 3 1 CPSF A subunit region PQQ_3 PF13570.6 GAM38192.1 - 0.44 11.1 7.9 8.7 7.0 0.0 5.0 5 0 0 5 5 5 0 PQQ-like domain MCM PF00493.23 GAM38193.1 - 2.3e-94 314.7 0.0 4.6e-94 313.7 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAM38193.1 - 1.5e-30 105.6 0.0 2.7e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAM38193.1 - 7.8e-25 87.1 0.8 1.5e-24 86.2 0.8 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAM38193.1 - 3.8e-12 46.7 0.0 1.4e-11 44.9 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAM38193.1 - 1.4e-06 27.9 0.0 1.6e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAM38193.1 - 0.003 17.4 0.0 0.0074 16.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAM38193.1 - 0.028 14.4 0.0 0.25 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 GAM38193.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain PBP1_TM PF14812.6 GAM38193.1 - 1.5 9.3 7.0 4.5 7.7 7.0 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIF_alpha PF05793.12 GAM38193.1 - 2.6 6.5 11.0 4 5.9 11.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PPR_2 PF13041.6 GAM38194.1 - 1.7e-19 69.7 3.2 2.5e-10 40.4 0.0 7.0 7 2 3 10 10 10 4 PPR repeat family PPR_3 PF13812.6 GAM38194.1 - 3e-16 59.3 0.0 8.7e-06 25.7 0.0 4.8 4 0 0 4 4 4 4 Pentatricopeptide repeat domain PPR PF01535.20 GAM38194.1 - 3e-13 49.1 10.7 0.0089 16.2 0.0 9.3 10 0 0 10 10 10 4 PPR repeat PPR_long PF17177.4 GAM38194.1 - 7.1e-06 25.5 0.0 0.075 12.4 0.0 4.1 3 1 2 5 5 5 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GAM38194.1 - 4.1e-05 23.2 1.0 3.2 7.5 0.1 4.8 5 0 0 5 5 5 1 PPR repeat TPR_12 PF13424.6 GAM38194.1 - 0.00063 20.0 0.8 0.24 11.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM38194.1 - 0.002 18.0 0.7 3.2 8.0 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM38194.1 - 0.014 15.3 0.6 0.07 13.0 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM38194.1 - 0.022 15.6 12.3 3.1 8.9 0.1 7.5 7 1 2 9 9 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM38194.1 - 0.049 14.3 0.4 1.1 10.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM38194.1 - 0.072 13.2 3.2 11 6.5 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM38194.1 - 0.081 13.2 0.8 3.2 8.2 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SRP68 PF16969.5 GAM38195.1 - 1.1e-187 625.5 0.6 1.2e-187 625.3 0.6 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 BRO1 PF03097.18 GAM38195.1 - 0.044 12.6 0.0 0.087 11.6 0.0 1.4 1 0 0 1 1 1 0 BRO1-like domain DUF3563 PF12086.8 GAM38195.1 - 0.9 9.3 4.8 6.9 6.5 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3563) p450 PF00067.22 GAM38196.1 - 3.2e-54 184.4 0.0 6.5e-54 183.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Rhodanese PF00581.20 GAM38197.1 - 7e-14 52.2 0.0 1.7e-13 51.0 0.0 1.6 1 1 1 2 2 2 1 Rhodanese-like domain Spo7 PF03907.13 GAM38198.1 - 2.5e-93 311.6 0.3 2.5e-93 311.6 0.3 2.2 2 0 0 2 2 2 1 Spo7-like protein GTP_EFTU PF00009.27 GAM38198.1 - 4.4e-33 114.5 0.0 2.3e-32 112.1 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAM38198.1 - 1.4e-19 70.1 0.0 5.1e-19 68.4 0.0 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 GAM38198.1 - 7.2e-12 45.5 6.3 2.2e-09 37.6 0.0 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 GAM38198.1 - 1.9e-09 37.3 0.3 5.7e-09 35.8 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 GAM38198.1 - 1.8e-06 28.0 0.1 1.5e-05 25.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 GAM38198.1 - 0.0037 17.5 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 GAM38198.1 - 0.046 13.5 0.0 0.16 11.7 0.0 2.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF1772 PF08592.11 GAM38198.1 - 3 8.2 4.3 31 4.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Abhydrolase_1 PF00561.20 GAM38199.1 - 1.6e-22 80.4 0.0 8.5e-21 74.7 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM38199.1 - 4e-17 62.3 0.0 3.2e-16 59.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM38199.1 - 1.2e-16 62.0 8.7 1.2e-16 62.0 5.6 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 GAM38199.1 - 3.6e-06 26.5 0.0 7.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 GAM38199.1 - 5.8e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 GAM38199.1 - 0.00059 18.8 0.0 0.00085 18.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Ser_hydrolase PF06821.13 GAM38199.1 - 0.00072 19.5 0.0 0.16 11.9 0.0 2.8 4 0 0 4 4 4 1 Serine hydrolase Abhydrolase_3 PF07859.13 GAM38199.1 - 0.0015 18.4 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 GAM38199.1 - 0.0018 18.1 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 GAM38199.1 - 0.0024 17.5 0.0 0.0054 16.3 0.0 1.6 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ndr PF03096.14 GAM38199.1 - 0.0076 15.0 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Chlorophyllase PF07224.11 GAM38199.1 - 0.0099 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Thioesterase PF00975.20 GAM38199.1 - 0.011 15.8 0.9 0.11 12.6 0.9 2.4 1 1 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 GAM38199.1 - 0.023 14.4 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_2 PF02230.16 GAM38199.1 - 0.05 13.4 0.0 5.3 6.8 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase PAT1 PF09770.9 GAM38200.1 - 0.061 11.6 6.7 0.081 11.2 6.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.9 GAM38200.1 - 9.5 4.6 9.6 14 4.1 9.6 1.3 1 0 0 1 1 1 0 Macoilin family WLM PF08325.10 GAM38201.1 - 8.9e-20 71.6 0.1 1.7e-19 70.7 0.1 1.4 1 0 0 1 1 1 1 WLM domain TPR_12 PF13424.6 GAM38201.1 - 7.6e-14 51.8 4.3 4.7e-06 26.8 0.1 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAM38201.1 - 1.1e-09 37.8 1.8 0.0091 15.8 0.1 4.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAM38201.1 - 3.2e-05 23.6 1.0 0.005 16.8 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM38201.1 - 9.4e-05 22.1 2.5 0.022 14.6 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM38201.1 - 0.00034 20.5 1.6 0.08 13.1 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM38201.1 - 0.004 17.8 0.3 0.51 11.0 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM38201.1 - 0.035 13.5 1.5 1.6 8.1 0.2 2.1 1 1 0 2 2 2 0 MalT-like TPR region TPR_19 PF14559.6 GAM38201.1 - 0.071 13.6 1.7 3 8.4 0.3 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM38201.1 - 0.082 13.2 0.7 0.47 10.8 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat COR PF16095.5 GAM38201.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 C-terminal of Roc, COR, domain TPR_6 PF13174.6 GAM38201.1 - 0.2 12.4 3.3 0.99 10.2 0.2 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat RPE65 PF03055.15 GAM38202.1 - 3.6e-72 244.1 0.0 4.4e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein MFS_1 PF07690.16 GAM38203.1 - 3.8e-25 88.6 24.4 7.7e-23 81.0 22.5 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM38203.1 - 5.2e-08 32.2 9.0 5.2e-08 32.2 9.0 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter Asp PF00026.23 GAM38204.1 - 1.6e-40 139.5 2.7 2e-40 139.2 2.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM38204.1 - 0.00047 20.5 0.6 0.0022 18.2 0.6 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 GAM38204.1 - 0.012 16.1 0.0 26 5.4 0.0 3.9 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease TatD_DNase PF01026.21 GAM38205.1 - 5.6e-34 117.7 0.0 3.3e-33 115.1 0.0 1.9 1 1 0 1 1 1 1 TatD related DNase CENP-B_dimeris PF09026.10 GAM38205.1 - 0.015 15.7 0.3 0.029 14.7 0.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 GAM38205.1 - 0.084 12.5 0.4 0.14 11.8 0.4 1.3 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 GAM38205.1 - 0.36 11.2 8.0 0.73 10.2 8.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.18 GAM38206.1 - 7.7e-19 67.8 0.0 1.6e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM38206.1 - 2.2e-08 34.1 7.8 3.9e-08 33.3 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sporozoite_P67 PF05642.11 GAM38206.1 - 0.29 9.2 3.0 0.44 8.6 3.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 GAM38206.1 - 1.7 6.9 8.1 2.5 6.3 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Fungal_trans PF04082.18 GAM38208.1 - 4.2e-19 68.6 0.1 9.8e-19 67.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM38208.1 - 4.2e-10 39.6 11.8 6.9e-10 38.9 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBFD_NFYB_HMF PF00808.23 GAM38209.1 - 2.3e-29 101.5 1.2 3.2e-29 101.0 1.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAM38209.1 - 3.9e-06 27.3 0.0 6.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 GAM38209.1 - 0.0011 18.9 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 GAM38209.1 - 0.0015 18.5 0.1 0.0025 17.8 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 GAM38209.1 - 0.0028 17.8 0.0 0.0038 17.3 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 GAM38209.1 - 0.047 14.2 0.0 0.086 13.3 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.20 GAM38210.1 - 2.9e-24 85.1 7.4 3.5e-24 84.8 7.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 GAM38210.1 - 0.016 15.1 4.3 1.1 9.2 4.3 2.2 1 1 0 1 1 1 0 Prefoldin subunit ATPase PF06745.13 GAM38210.1 - 0.057 12.7 1.2 3.6 6.9 0.2 2.0 1 1 1 2 2 2 0 KaiC CC2-LZ PF16516.5 GAM38210.1 - 0.075 13.4 7.6 1.1 9.7 2.8 2.1 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator MCR_beta PF02241.18 GAM38210.1 - 0.099 12.2 0.3 0.11 12.1 0.3 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain DUF4376 PF14301.6 GAM38210.1 - 0.11 12.9 3.6 7.2 7.0 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) DUF3450 PF11932.8 GAM38210.1 - 0.6 9.4 9.7 1.4 8.2 4.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) APH PF01636.23 GAM38211.1 - 9.7e-30 104.3 0.1 1.5e-29 103.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 GAM38211.1 - 0.00027 19.9 0.0 0.29 9.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 GAM38211.1 - 0.0048 16.1 0.1 0.092 11.9 0.0 2.0 2 0 0 2 2 2 1 Fructosamine kinase HA2 PF04408.23 GAM38212.1 - 3e-21 75.7 1.7 1.3e-20 73.6 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAM38212.1 - 1.4e-17 63.8 0.0 9.5e-17 61.1 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAM38212.1 - 4.5e-15 55.9 0.0 1e-14 54.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM38212.1 - 2.4e-06 27.4 0.1 6.9e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAM38212.1 - 8.1e-05 22.9 0.1 0.00024 21.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAM38212.1 - 0.0015 17.7 0.0 0.0042 16.2 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 GAM38212.1 - 0.0019 18.0 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 GAM38212.1 - 0.0024 17.5 0.4 0.0074 15.9 0.4 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ATPase PF06745.13 GAM38212.1 - 0.0027 17.1 0.0 0.0052 16.2 0.0 1.4 1 0 0 1 1 1 1 KaiC DUF2075 PF09848.9 GAM38212.1 - 0.0037 16.6 0.0 0.0069 15.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 GAM38212.1 - 0.008 16.5 0.3 0.036 14.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 GAM38212.1 - 0.019 14.9 0.0 8.8 6.3 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 GAM38212.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain NACHT PF05729.12 GAM38212.1 - 0.034 14.1 1.3 0.22 11.4 0.5 2.5 2 1 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 GAM38212.1 - 0.046 13.8 0.2 0.25 11.4 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAM38212.1 - 0.084 13.0 0.4 0.67 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAM38212.1 - 0.14 12.5 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 GAM38212.1 - 0.23 11.9 1.5 0.36 11.4 0.0 2.1 3 0 0 3 3 1 0 ABC transporter DAD PF02109.16 GAM38213.1 - 2.5e-32 111.4 2.9 5.9e-32 110.2 2.9 1.6 1 1 0 1 1 1 1 DAD family Mucin PF01456.17 GAM38213.1 - 0.4 10.7 22.0 0.68 9.9 0.2 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Alpha_GJ PF03229.13 GAM38213.1 - 1.3 9.6 16.0 2.6 8.6 0.1 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J GFO_IDH_MocA PF01408.22 GAM38214.1 - 3.8e-19 69.7 0.0 1.4e-18 67.8 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold BCA_ABC_TP_C PF12399.8 GAM38214.1 - 0.012 15.5 0.1 0.037 14.0 0.1 1.9 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter NAD_binding_3 PF03447.16 GAM38214.1 - 0.15 12.8 0.1 0.31 11.7 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Fungal_trans PF04082.18 GAM38217.1 - 0.0003 19.9 0.0 0.00052 19.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM38217.1 - 0.0023 18.0 11.7 0.0045 17.1 11.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LicD PF04991.13 GAM38218.1 - 1.1e-22 81.3 8.0 5.9e-16 59.3 0.9 2.8 2 1 1 3 3 3 2 LicD family Fungal_trans PF04082.18 GAM38219.1 - 1.2e-17 63.8 0.0 2.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM38219.1 - 1.8e-10 40.8 10.4 3.7e-10 39.7 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sin_N PF04801.13 GAM38219.1 - 0.13 11.5 4.5 1.9 7.6 0.1 2.2 2 0 0 2 2 2 0 Sin-like protein conserved region DUF726 PF05277.12 GAM38220.1 - 3.6e-126 420.7 3.1 4.9e-126 420.3 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) RTC4 PF14474.6 GAM38221.1 - 5.2e-30 104.1 0.0 1.4e-29 102.7 0.0 1.7 2 0 0 2 2 2 1 RTC4-like domain TFR_dimer PF04253.15 GAM38222.1 - 2.1e-30 105.3 0.0 3.9e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 GAM38222.1 - 1.2e-21 77.3 0.0 1.9e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 GAM38222.1 - 7.7e-12 45.1 0.4 3.4e-11 43.0 0.4 2.1 1 1 0 1 1 1 1 PA domain Nicastrin PF05450.15 GAM38222.1 - 0.0054 16.2 0.0 0.0095 15.4 0.0 1.3 1 0 0 1 1 1 1 Nicastrin MFS_1 PF07690.16 GAM38223.1 - 1.2e-33 116.6 14.7 2e-33 115.8 14.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Tmemb_14 PF03647.13 GAM38224.1 - 1.5e-21 76.9 5.9 1.8e-21 76.6 5.9 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C zf-C2H2_4 PF13894.6 GAM38225.1 - 7e-07 29.6 2.0 0.0077 17.0 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM38225.1 - 0.00029 21.1 2.8 0.012 16.0 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type Ima1_N PF09779.9 GAM38225.1 - 0.68 10.8 2.4 0.7 10.7 0.2 2.1 2 1 0 2 2 2 0 Ima1 N-terminal domain DUF5427 PF10310.9 GAM38228.1 - 9.5e-165 549.1 3.8 4.2e-164 546.9 3.8 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 GAM38228.1 - 0.0061 16.7 2.6 0.0099 16.1 0.9 2.0 2 0 0 2 2 2 1 Influenza Matrix protein (M1) C-terminal domain SARAF PF06682.12 GAM38228.1 - 0.29 10.7 4.3 0.44 10.2 4.3 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Ndc1_Nup PF09531.10 GAM38228.1 - 0.7 8.5 4.1 1.1 7.8 4.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC27 PF09507.10 GAM38228.1 - 2.7 7.3 13.9 4.5 6.5 13.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SurE PF01975.17 GAM38229.1 - 7.5e-51 172.7 0.0 1.6e-50 171.6 0.0 1.5 1 1 0 1 1 1 1 Survival protein SurE Glyco_trans_4_4 PF13579.6 GAM38229.1 - 0.077 13.4 0.0 0.2 12.1 0.0 1.8 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain Zn_clus PF00172.18 GAM38230.1 - 0.0029 17.7 10.4 0.0054 16.8 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WW_FCH_linker PF16623.5 GAM38230.1 - 0.043 14.6 0.6 0.13 13.0 0.6 1.8 1 0 0 1 1 1 0 Unstructured linker region between on GAS7 protein DUF2462 PF09495.10 GAM38231.1 - 3.8e-18 66.0 10.3 3.8e-18 66.0 10.3 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Golgin_A5 PF09787.9 GAM38232.1 - 0.0034 16.9 3.9 0.0034 16.9 3.9 1.9 2 0 0 2 2 2 1 Golgin subfamily A member 5 CEP209_CC5 PF16574.5 GAM38232.1 - 0.071 13.3 3.0 0.16 12.1 3.0 1.6 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 Tropomyosin_1 PF12718.7 GAM38232.1 - 0.24 11.5 12.5 0.031 14.4 5.0 2.9 2 1 0 2 2 2 0 Tropomyosin like TMF_DNA_bd PF12329.8 GAM38232.1 - 0.75 9.8 7.9 11 6.0 0.6 3.7 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding GPI-anchored PF10342.9 GAM38233.1 - 4.5e-22 78.6 1.0 4.5e-22 78.6 1.0 2.8 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 GAM38233.1 - 0.044 13.6 0.2 0.12 12.2 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4538 PF15061.6 GAM38233.1 - 3.7 7.4 4.2 0.85 9.4 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) RTA1 PF04479.13 GAM38234.1 - 1.1e-61 208.1 5.6 1.2e-61 207.9 5.6 1.0 1 0 0 1 1 1 1 RTA1 like protein DAD PF02109.16 GAM38234.1 - 0.086 13.2 0.7 0.2 12.0 0.7 1.6 1 0 0 1 1 1 0 DAD family NDUF_B12 PF08122.12 GAM38234.1 - 0.48 10.5 3.4 0.85 9.7 0.4 2.5 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF202 PF02656.15 GAM38234.1 - 1.4 9.4 6.4 18 5.8 0.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF202) MFS_1 PF07690.16 GAM38235.1 - 3.8e-46 157.6 61.7 6.9e-42 143.6 35.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM38235.1 - 4.7e-12 45.5 4.8 4.7e-12 45.5 4.8 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter PTR2 PF00854.21 GAM38235.1 - 0.2 10.5 9.4 0.83 8.4 1.2 2.7 3 0 0 3 3 3 0 POT family NADHdh_A3 PF14987.6 GAM38235.1 - 0.21 11.9 0.3 0.21 11.9 0.3 2.6 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Fungal_trans PF04082.18 GAM38236.1 - 2.6e-20 72.6 0.1 3.8e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM38236.1 - 0.00062 19.8 15.3 0.0013 18.8 15.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 GAM38237.1 - 7.4e-10 38.9 0.2 1.5e-09 37.9 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM38237.1 - 5.8e-08 33.6 4.5 8.4e-08 33.1 4.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM38237.1 - 1.9e-05 24.1 0.0 3.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 GAM38237.1 - 0.0022 17.6 0.1 0.0038 16.9 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.14 GAM38237.1 - 0.055 12.2 0.1 0.086 11.5 0.1 1.2 1 0 0 1 1 1 0 Ndr family Cu-oxidase_3 PF07732.15 GAM38238.1 - 4e-43 146.2 6.2 1.3e-42 144.6 1.8 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 GAM38238.1 - 5.8e-32 111.0 0.6 3.4e-30 105.3 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAM38238.1 - 1.2e-31 109.2 8.7 3e-29 101.5 0.7 3.6 3 1 0 3 3 3 2 Multicopper oxidase LOR PF04525.12 GAM38239.1 - 4.3e-08 33.0 0.1 6.2e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 LURP-one-related Protoglobin PF11563.8 GAM38242.1 - 1.4e-59 200.5 0.1 1.7e-59 200.2 0.1 1.1 1 0 0 1 1 1 1 Protoglobin Casein_kappa PF00997.18 GAM38243.1 - 0.19 11.8 0.1 0.3 11.2 0.1 1.2 1 0 0 1 1 1 0 Kappa casein Cellulase PF00150.18 GAM38244.1 - 1.5e-17 64.0 4.1 2.9e-17 63.0 4.1 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) nec1 PF10379.9 GAM38244.1 - 0.1 12.1 0.1 0.1 12.1 0.1 1.7 2 0 0 2 2 2 0 Virulence protein nec1 IBN_N PF03810.19 GAM38245.1 - 1.9e-15 56.5 0.7 1.5e-13 50.4 0.2 3.3 3 0 0 3 3 3 2 Importin-beta N-terminal domain Phosphoesterase PF04185.14 GAM38247.1 - 1.7e-34 119.6 4.7 6.2e-34 117.7 4.7 1.9 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 GAM38247.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain Pex2_Pex12 PF04757.14 GAM38248.1 - 1.7e-39 135.8 2.2 2.4e-39 135.2 2.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 GAM38248.1 - 0.00014 22.0 5.3 0.00029 20.9 5.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 GAM38248.1 - 0.039 13.8 1.5 0.085 12.8 1.5 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM38248.1 - 0.077 13.0 3.7 0.28 11.2 3.7 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAM38248.1 - 0.27 11.1 3.1 0.3 10.9 0.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ER_lumen_recept PF00810.18 GAM38249.1 - 6.4e-26 91.9 8.7 2.2e-23 83.7 8.7 2.5 1 1 0 1 1 1 1 ER lumen protein retaining receptor DUF5368 PF17336.2 GAM38249.1 - 8.3e-05 22.7 0.1 0.00021 21.4 0.1 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5368) DUF2499 PF10693.9 GAM38249.1 - 0.073 13.3 1.3 1.2 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2499) Ribosomal_L27A PF00828.19 GAM38250.1 - 4.7e-23 82.2 0.0 7e-23 81.7 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RAP PF08373.10 GAM38250.1 - 0.13 12.4 0.9 0.19 11.9 0.9 1.3 1 0 0 1 1 1 0 RAP domain eRF1_1 PF03463.15 GAM38251.1 - 2.3e-45 153.7 0.0 3.4e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 GAM38251.1 - 2.1e-19 70.1 0.0 3.9e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 GAM38251.1 - 6.4e-18 65.4 0.0 9.5e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Ribosomal_S19e PF01090.19 GAM38253.1 - 2.7e-53 179.3 0.1 4.7e-53 178.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_6 PF12697.7 GAM38253.1 - 3.9e-16 60.3 0.5 1.2e-15 58.7 0.3 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM38253.1 - 1.2e-14 54.5 0.0 1.5e-13 51.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.20 GAM38253.1 - 9.8e-11 41.6 0.0 2.5e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Hydrolase_4 PF12146.8 GAM38253.1 - 4.3e-09 36.0 0.0 1.7e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 GAM38253.1 - 0.0014 18.5 0.2 0.0036 17.2 0.2 1.7 1 0 0 1 1 1 1 Serine hydrolase Y_phosphatase PF00102.27 GAM38253.1 - 0.0023 17.5 0.0 0.019 14.6 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Thioesterase PF00975.20 GAM38253.1 - 0.0099 16.0 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 GAM38253.1 - 0.022 14.5 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 PGAP1-like protein PTPlike_phytase PF14566.6 GAM38253.1 - 0.11 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate FSH1 PF03959.13 GAM38253.1 - 0.11 12.1 0.0 1.8 8.2 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 GAM38253.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase ILVD_EDD PF00920.21 GAM38254.1 - 1.1e-212 707.3 0.5 1.3e-212 707.1 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1772 PF08592.11 GAM38255.1 - 4.9e-13 49.6 0.1 5.5e-13 49.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) 2OG-FeII_Oxy_3 PF13640.6 GAM38256.1 - 4.4e-08 33.9 0.0 9.7e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF916 PF06030.12 GAM38257.1 - 0.017 15.2 0.5 0.071 13.2 0.5 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) VCBS PF13517.6 GAM38258.1 - 2e-08 34.7 22.5 0.00085 19.9 2.6 4.3 2 2 3 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_1 PF00036.32 GAM38258.1 - 7.2e-06 25.2 1.3 2.7 7.8 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 GAM38258.1 - 0.00043 20.0 1.7 2.5 8.2 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 GAM38258.1 - 0.00054 19.9 2.1 1.4 8.9 0.0 3.3 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 GAM38258.1 - 0.0098 16.3 0.6 4.5 7.8 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair Lipase_C PF18067.1 GAM38258.1 - 0.046 14.3 0.3 1.8 9.2 0.1 2.5 2 1 0 2 2 2 0 Lipase C-terminal domain EF-hand_5 PF13202.6 GAM38258.1 - 0.087 12.4 7.4 1.5 8.5 0.4 3.3 3 0 0 3 3 3 0 EF hand CotH PF08757.11 GAM38258.1 - 0.09 12.3 8.8 3.6 7.0 1.7 3.2 1 1 2 3 3 3 0 CotH kinase protein FG-GAP PF01839.23 GAM38258.1 - 0.11 12.7 9.1 3.3 7.9 0.0 3.7 3 0 0 3 3 3 0 FG-GAP repeat Phage_head_chap PF11113.8 GAM38258.1 - 0.15 12.2 0.4 66 3.7 0.0 3.7 3 0 0 3 3 3 0 Head assembly gene product S_locus_glycop PF00954.20 GAM38258.1 - 0.92 10.1 2.7 6 7.4 0.5 2.5 1 1 1 2 2 2 0 S-locus glycoprotein domain SHIRT PF18655.1 GAM38258.1 - 3.5 8.3 10.1 13 6.4 0.4 4.2 2 1 3 5 5 5 0 SHIRT domain Aminotran_3 PF00202.21 GAM38259.1 - 3e-44 151.3 0.5 3.7e-43 147.7 0.5 2.2 1 1 0 1 1 1 1 Aminotransferase class-III Myb_DNA-bind_6 PF13921.6 GAM38261.1 - 3e-06 27.4 0.0 0.074 13.3 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAM38261.1 - 0.00022 21.3 1.1 0.0014 18.8 0.2 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAM38262.1 - 9.1e-14 51.4 3.2 2.8e-09 37.0 0.8 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM38262.1 - 4.1e-09 36.5 3.6 8.9e-06 25.9 0.8 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAM38262.1 - 0.057 13.3 0.4 0.057 13.3 0.4 2.1 2 1 0 3 3 3 0 Myb DNA-binding like GET2 PF08690.10 GAM38262.1 - 1.3 8.7 5.0 1.7 8.2 5.0 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 SUIM_assoc PF16619.5 GAM38262.1 - 3.6 7.7 15.2 0.79 9.8 2.2 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Transp_cyt_pur PF02133.15 GAM38263.1 - 7.1e-13 48.1 41.6 1.4e-12 47.2 41.5 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COX5B PF01215.19 GAM38264.1 - 8.2e-54 180.8 0.0 1.1e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb SchA_CurD PF04486.12 GAM38266.1 - 0.069 13.3 0.0 0.6 10.2 0.0 2.3 3 0 0 3 3 3 0 SchA/CurD like domain HSCB_C PF07743.13 GAM38266.1 - 0.61 10.6 4.9 0.48 10.9 1.3 2.7 1 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF883 PF05957.13 GAM38266.1 - 1.3 9.7 4.5 1.7 9.3 0.2 2.9 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Myb_DNA-bind_6 PF13921.6 GAM38267.1 - 1.4e-12 47.7 0.0 3.2e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAM38267.1 - 4.4e-10 39.6 2.4 0.00012 22.2 0.0 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain DUF1937 PF09152.10 GAM38267.1 - 0.026 15.3 0.0 0.056 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1937) tRNA-synt_1b PF00579.25 GAM38268.1 - 2.4e-21 76.4 0.0 1.4e-20 73.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) PROCN PF08083.11 GAM38269.1 - 2.3e-235 780.8 7.4 2.3e-235 780.8 7.4 1.9 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 GAM38269.1 - 5.9e-126 418.7 0.8 1e-125 417.9 0.8 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 GAM38269.1 - 6e-89 296.0 2.0 1.9e-88 294.4 2.0 2.0 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 GAM38269.1 - 1.5e-81 271.8 2.0 4.3e-81 270.2 2.0 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 GAM38269.1 - 2.3e-71 238.1 0.1 6.4e-71 236.7 0.1 1.8 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 GAM38269.1 - 2.2e-48 163.2 0.1 6.5e-48 161.7 0.1 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 GAM38269.1 - 2.8e-48 162.2 0.3 7.7e-48 160.8 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Ribosomal_L34e PF01199.18 GAM38270.1 - 9e-43 144.5 2.7 1.3e-42 143.9 2.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 GAM38270.1 - 0.031 13.7 0.9 0.062 12.7 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FhuF_C PF11575.8 GAM38270.1 - 0.81 9.7 4.9 3.5 7.7 0.3 2.7 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Cactin_mid PF10312.9 GAM38271.1 - 1.6e-63 214.1 5.9 3e-63 213.1 5.9 1.5 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 GAM38271.1 - 2.4e-56 189.0 3.7 4.9e-56 188.1 3.7 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Forkhead PF00250.18 GAM38271.1 - 4e-20 71.9 1.1 4e-20 71.9 1.1 2.7 3 0 0 3 3 3 1 Forkhead domain SF3A2 PF16835.5 GAM38271.1 - 0.032 14.6 0.0 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF1087 PF06465.13 GAM38271.1 - 0.075 13.1 1.0 0.18 11.9 0.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) XLF PF09302.11 GAM38272.1 - 1.4e-44 152.4 1.2 1.4e-44 152.4 1.2 1.8 2 0 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component WD40 PF00400.32 GAM38273.1 - 1.7e-15 57.1 10.0 2.1e-06 28.3 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM38273.1 - 3.7e-06 27.2 0.1 1.1 9.6 0.0 4.6 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM38273.1 - 6.9e-06 26.1 0.1 0.0045 16.9 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Zn_ribbon_17 PF17120.5 GAM38273.1 - 0.036 13.7 9.1 0.091 12.4 9.1 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type HSP20 PF00011.21 GAM38273.1 - 0.11 12.6 0.2 0.26 11.5 0.2 1.5 1 0 0 1 1 1 0 Hsp20/alpha crystallin family zf-rbx1 PF12678.7 GAM38273.1 - 3.7 7.9 10.0 0.14 12.5 0.8 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAM38273.1 - 6.8 6.8 7.6 2.6 8.2 0.9 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger ABC_membrane PF00664.23 GAM38274.1 - 3e-35 122.2 7.2 3e-35 122.2 7.2 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAM38274.1 - 5.9e-33 114.3 0.0 2.1e-32 112.5 0.0 2.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GAM38274.1 - 1.1e-07 31.6 0.2 1.5e-06 27.8 0.2 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAM38274.1 - 0.0081 16.4 0.2 0.067 13.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GAM38274.1 - 0.022 14.5 1.3 0.098 12.4 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 GAM38274.1 - 0.025 14.8 3.2 0.18 12.0 0.9 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 GAM38274.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 GAM38274.1 - 0.37 11.2 3.7 8.3 6.8 3.7 2.7 1 1 0 1 1 1 0 AAA ATPase domain VanZ PF04892.12 GAM38274.1 - 5.1 7.8 10.1 5.7 7.6 0.0 3.5 5 0 0 5 5 5 0 VanZ like family Ank_2 PF12796.7 GAM38275.1 - 6.9e-22 77.8 0.0 9.4e-11 42.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM38275.1 - 8.3e-20 70.9 7.4 1.1e-09 38.6 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM38275.1 - 6.6e-18 63.0 0.5 0.0023 18.3 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 GAM38275.1 - 2.3e-16 59.4 0.9 1.1e-05 25.6 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 GAM38275.1 - 2.4e-13 50.0 0.1 1.1e-05 25.6 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) adh_short PF00106.25 GAM38276.1 - 2.7e-22 79.2 0.0 4.8e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM38276.1 - 3.7e-15 56.1 0.0 8.7e-15 54.9 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM38276.1 - 3.4e-09 36.9 0.0 1.4e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAM38276.1 - 0.00085 18.9 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM38276.1 - 0.00087 19.2 0.0 0.0016 18.4 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Abhydrolase_3 PF07859.13 GAM38277.1 - 5.4e-46 157.1 0.0 9.4e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DAO PF01266.24 GAM38277.1 - 3.5e-21 76.2 0.0 5.8e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase COesterase PF00135.28 GAM38277.1 - 5.3e-07 28.9 0.0 9.6e-07 28.0 0.0 1.4 1 0 0 1 1 1 1 Carboxylesterase family AA_permease PF00324.21 GAM38278.1 - 1.3e-114 383.5 42.8 1.5e-114 383.3 42.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM38278.1 - 1e-23 83.9 46.2 1.6e-23 83.3 46.2 1.3 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.18 GAM38279.1 - 0.00082 19.4 10.3 0.0012 18.9 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF498 PF04430.14 GAM38280.1 - 3.1e-29 101.2 0.0 4.7e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Alk_phosphatase PF00245.20 GAM38281.1 - 1.6e-108 363.3 0.0 1.9e-108 363.1 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 GAM38281.1 - 4.6e-06 26.2 0.0 9.9e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF3425 PF11905.8 GAM38282.1 - 8.4e-20 71.0 0.1 1.8e-19 69.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Aldo_ket_red PF00248.21 GAM38283.1 - 5.4e-64 216.2 0.0 6.5e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_16 PF00722.21 GAM38285.1 - 1.8e-19 69.9 0.6 4.5e-19 68.6 0.6 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 GAM38285.1 - 0.96 10.0 21.4 0.1 13.1 16.7 1.8 2 0 0 2 2 2 0 Chitin recognition protein DUF1180 PF06679.12 GAM38285.1 - 6.1 7.2 8.5 9.2 6.6 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2890 PF11081.8 GAM38286.1 - 1.2 9.2 5.9 1.8 8.7 5.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Pro_dh PF01619.18 GAM38287.1 - 2.5e-63 214.4 0.0 3e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase PMSR PF01625.21 GAM38288.1 - 4.6e-63 212.0 1.2 5.5e-63 211.7 1.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase KaiA PF07688.12 GAM38288.1 - 0.2 11.8 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 KaiA C-terminal domain Kinesin PF00225.23 GAM38289.1 - 3.2e-118 394.5 0.7 4.6e-118 394.0 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAM38289.1 - 6.6e-28 97.5 0.3 2e-27 95.9 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding AAA_33 PF13671.6 GAM38289.1 - 0.0075 16.4 0.1 0.04 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Herpes_UL14 PF03580.14 GAM38289.1 - 0.0077 16.5 4.6 0.022 15.0 4.6 1.7 1 0 0 1 1 1 1 Herpesvirus UL14-like protein Tim17 PF02466.19 GAM38291.1 - 8.3e-05 22.9 0.9 0.00012 22.4 0.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family cNMP_binding PF00027.29 GAM38292.1 - 6.5e-36 122.3 0.0 2e-21 75.9 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 GAM38292.1 - 2.2e-35 122.5 7.0 2.2e-35 122.5 7.0 3.3 4 0 0 4 4 4 1 Unstructured region on cNMP-binding protein F-box-like PF12937.7 GAM38292.1 - 6.6e-08 32.3 1.0 1.8e-07 30.9 1.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM38292.1 - 5.1e-06 26.2 4.7 5.7e-06 26.1 1.6 2.5 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 GAM38292.1 - 0.00018 21.8 0.1 1.8 9.1 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) SAM_Ste50p PF09235.10 GAM38292.1 - 0.58 10.4 2.4 30 4.9 0.1 4.0 4 0 0 4 4 4 0 Ste50p, sterile alpha motif DUF5102 PF17104.5 GAM38293.1 - 1.8e-110 369.6 0.3 1.8e-110 369.6 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5102) Nsp1_C PF05064.13 GAM38294.1 - 6.2e-39 132.4 0.9 6.2e-39 132.4 0.9 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 GAM38294.1 - 3.2e-13 50.3 134.3 1.5e-06 28.9 24.5 6.4 2 1 5 7 7 6 4 Nucleoporin FG repeat region Tic110 PF16940.5 GAM38294.1 - 0.03 12.8 2.0 0.077 11.5 2.0 1.7 1 0 0 1 1 1 0 Chloroplast envelope transporter ParB PF08775.10 GAM38294.1 - 0.052 14.0 0.7 0.052 14.0 0.7 1.7 2 0 0 2 2 1 0 ParB family Laminin_II PF06009.12 GAM38294.1 - 0.19 11.7 10.5 0.52 10.3 2.9 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 GAM38294.1 - 0.22 11.6 5.5 0.5 10.4 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 GAM38294.1 - 0.25 11.6 3.9 0.97 9.7 0.3 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SGT1 PF07093.11 GAM38294.1 - 0.35 9.3 3.0 0.48 8.8 3.0 1.1 1 0 0 1 1 1 0 SGT1 protein GAT PF03127.14 GAM38294.1 - 0.41 11.0 1.2 1.9 8.9 0.1 2.4 1 1 1 2 2 2 0 GAT domain OmpH PF03938.14 GAM38294.1 - 0.72 10.2 12.9 0.37 11.1 3.0 2.8 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.6 GAM38294.1 - 1 7.9 7.7 0.36 9.4 2.8 1.9 1 1 1 2 2 2 0 AAA domain Snapin_Pallidin PF14712.6 GAM38294.1 - 1.3 9.4 6.0 1.7 9.1 0.2 2.6 3 0 0 3 3 2 0 Snapin/Pallidin TACC_C PF05010.14 GAM38294.1 - 1.6 8.5 9.5 12 5.6 9.3 2.1 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FapA PF03961.13 GAM38294.1 - 2 6.9 6.2 4.9 5.6 0.4 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A CENP-Q PF13094.6 GAM38294.1 - 2.6 8.2 7.8 4.6 7.4 7.8 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4200 PF13863.6 GAM38294.1 - 2.9 8.3 12.5 1.6 9.2 4.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CK2S PF15011.6 GAM38294.1 - 3.1 7.7 6.4 17 5.2 0.2 2.4 2 0 0 2 2 2 0 Casein Kinase 2 substrate Uso1_p115_C PF04871.13 GAM38294.1 - 3.7 7.9 8.6 22 5.4 5.7 2.9 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region IFT57 PF10498.9 GAM38294.1 - 4.1 6.3 10.0 1.5 7.7 2.8 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF16 PF01519.16 GAM38294.1 - 4.5 7.8 6.9 74 3.9 6.7 2.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 GAM38294.1 - 4.8 7.6 7.3 10 6.6 0.2 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 GAM38294.1 - 6 7.2 6.6 6 7.2 0.8 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HIP1_clath_bdg PF16515.5 GAM38294.1 - 7.4 7.2 10.9 1e+02 3.6 7.0 2.8 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2205 PF10224.9 GAM38295.1 - 2.3e-34 117.2 2.0 3.4e-34 116.7 2.0 1.2 1 0 0 1 1 1 1 Short coiled-coil protein DUF3450 PF11932.8 GAM38295.1 - 0.0014 18.0 4.1 0.0018 17.7 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) YabA PF06156.13 GAM38295.1 - 0.0077 16.9 2.7 0.011 16.4 2.7 1.2 1 0 0 1 1 1 1 Initiation control protein YabA CASP_C PF08172.12 GAM38295.1 - 0.0095 15.3 3.6 0.013 14.8 3.6 1.2 1 0 0 1 1 1 1 CASP C terminal RBD-FIP PF09457.10 GAM38295.1 - 0.018 15.0 0.1 0.038 13.9 0.1 1.6 1 0 0 1 1 1 0 FIP domain bZIP_1 PF00170.21 GAM38295.1 - 0.085 13.0 4.8 0.23 11.6 4.6 1.8 1 1 1 2 2 2 0 bZIP transcription factor JIP_LZII PF16471.5 GAM38295.1 - 0.088 13.0 3.5 0.2 11.9 3.5 1.6 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II DivIC PF04977.15 GAM38295.1 - 0.099 12.4 4.1 0.16 11.8 4.1 1.4 1 0 0 1 1 1 0 Septum formation initiator XhlA PF10779.9 GAM38295.1 - 0.22 11.8 1.0 0.38 11.0 0.6 1.6 1 1 1 2 2 2 0 Haemolysin XhlA DUF5320 PF17253.2 GAM38295.1 - 0.57 11.3 3.7 1.4 10.0 2.2 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5320) 14-3-3 PF00244.20 GAM38296.1 - 1.2e-105 351.9 5.6 1.5e-105 351.7 5.6 1.0 1 0 0 1 1 1 1 14-3-3 protein IATP PF04568.12 GAM38297.1 - 1.1e-29 102.7 0.7 1.2e-29 102.6 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP BLOC1_2 PF10046.9 GAM38297.1 - 0.011 16.0 2.4 0.014 15.7 2.4 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TssO PF17561.2 GAM38297.1 - 0.03 14.4 1.7 0.037 14.1 1.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO AdoHcyase PF05221.17 GAM38297.1 - 0.041 13.0 0.3 0.053 12.7 0.3 1.1 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase NPV_P10 PF05531.12 GAM38297.1 - 0.051 14.1 0.6 0.071 13.6 0.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 GAM38297.1 - 0.065 13.0 3.3 0.097 12.5 3.3 1.3 1 0 0 1 1 1 0 Septum formation initiator PKHD_C PF18331.1 GAM38297.1 - 0.12 12.4 0.1 0.3 11.2 0.1 1.6 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain DUF4140 PF13600.6 GAM38297.1 - 0.31 11.5 2.6 0.37 11.2 2.6 1.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Glyco_hydro_76 PF03663.14 GAM38298.1 - 3.1e-22 79.6 0.0 9.8e-22 78.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 DUF3320 PF11784.8 GAM38298.1 - 0.1 12.6 0.2 0.21 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) Bax1-I PF01027.20 GAM38299.1 - 1.6e-32 113.0 8.3 2.4e-32 112.5 8.3 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 RRM_1 PF00076.22 GAM38299.1 - 1.6e-14 53.4 0.0 2.7e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM38299.1 - 0.038 13.6 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF963 PF06131.11 GAM38299.1 - 0.078 12.4 2.6 0.15 11.5 2.6 1.4 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) CGI-121 PF08617.10 GAM38300.1 - 1.6e-53 181.1 0.4 1.9e-53 180.9 0.4 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Slx4 PF09494.10 GAM38301.1 - 1.1e-23 83.0 0.1 2.6e-23 81.7 0.1 1.7 1 0 0 1 1 1 1 Slx4 endonuclease PhyH PF05721.13 GAM38302.1 - 3.2e-15 57.0 0.0 4.3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) zf-MIZ PF02891.20 GAM38303.1 - 2.5e-09 36.7 0.1 5.1e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 GAM38303.1 - 5.4e-05 22.9 0.1 0.00011 21.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PhnI PF05861.12 GAM38304.1 - 0.12 11.2 0.1 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) PH PF00169.29 GAM38305.1 - 6.6e-12 45.9 0.0 1.9e-11 44.4 0.0 1.8 1 1 0 1 1 1 1 PH domain SH3_9 PF14604.6 GAM38305.1 - 9e-11 41.5 0.4 2.3e-10 40.2 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SAM_2 PF07647.17 GAM38305.1 - 4.5e-10 39.5 0.1 7.6e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 GAM38305.1 - 1.3e-09 37.5 0.2 3.2e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 GAM38305.1 - 0.00023 20.8 0.1 0.00046 19.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 GAM38305.1 - 0.012 16.0 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain SAM_1 PF00536.30 GAM38305.1 - 0.037 14.5 0.1 0.082 13.4 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_8 PF15409.6 GAM38305.1 - 0.047 14.0 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain adh_short_C2 PF13561.6 GAM38306.1 - 1.3e-54 185.3 7.4 2.6e-53 181.0 7.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM38306.1 - 1.4e-41 142.1 9.0 1.2e-40 139.1 9.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM38306.1 - 7e-10 39.1 1.4 1.5e-09 38.1 1.4 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM38306.1 - 5.2e-05 22.5 1.7 8.9e-05 21.8 1.7 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 GAM38306.1 - 7.1e-05 21.9 1.8 0.00011 21.3 1.8 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM38306.1 - 9.3e-05 22.0 1.1 0.00014 21.4 1.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAM38306.1 - 0.1 12.8 1.4 0.2 11.9 1.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ketoacyl-synt PF00109.26 GAM38307.1 - 6.7e-66 222.4 0.0 8.6e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAM38307.1 - 5.2e-21 74.8 0.1 1.3e-20 73.5 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAM38307.1 - 9.7e-10 38.9 0.0 1.8e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 GAM38307.1 - 6.1e-05 22.5 0.1 0.0001 21.8 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 GAM38307.1 - 0.011 15.5 0.7 0.027 14.3 0.7 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PS-DH PF14765.6 GAM38308.1 - 2.3e-36 125.6 0.0 3e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Diphthamide_syn PF01866.17 GAM38311.1 - 4.6e-88 295.6 0.0 6.7e-88 295.0 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Fe-ADH PF00465.19 GAM38312.1 - 1.9e-79 267.1 0.2 2.2e-79 266.9 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 GAM38312.1 - 1.9e-15 57.3 0.1 2.6e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase IMS_C PF11799.8 GAM38312.1 - 0.11 13.2 0.0 0.31 11.8 0.0 1.9 1 1 0 1 1 1 0 impB/mucB/samB family C-terminal domain ANAPC4_WD40 PF12894.7 GAM38313.1 - 1.8e-09 37.7 0.1 0.0024 18.1 0.0 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAM38313.1 - 0.0005 20.8 4.7 1.9 9.5 0.0 4.8 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF547 PF04784.14 GAM38313.1 - 0.21 11.6 0.0 0.46 10.5 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF547 Glyco_hydro_3_C PF01915.22 GAM38314.1 - 4.7e-63 212.8 0.0 1.1e-62 211.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 GAM38314.1 - 4e-21 74.9 0.0 1.1e-20 73.5 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 GAM38314.1 - 5.9e-19 68.3 0.0 1.1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Glyco_hydro_3 PF00933.21 GAM38314.1 - 1.2e-18 67.6 0.0 1.8e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain GLEYA PF10528.9 GAM38314.1 - 0.015 15.7 0.0 0.047 14.1 0.0 1.9 1 1 0 1 1 1 0 GLEYA domain Sugar_tr PF00083.24 GAM38315.1 - 4.7e-76 256.5 24.2 5.6e-76 256.2 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM38315.1 - 4.8e-23 81.7 69.4 2.2e-20 72.9 32.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM38315.1 - 2.1e-07 29.9 26.3 5.8e-05 21.8 2.7 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Iron_permease PF04120.12 GAM38316.1 - 8.8e-44 148.4 7.1 1.1e-19 70.5 0.1 4.2 4 0 0 4 4 4 4 Low affinity iron permease DUF2839 PF10999.8 GAM38316.1 - 1.5 9.2 6.6 0.72 10.3 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) adh_short PF00106.25 GAM38317.1 - 4.9e-38 130.5 0.0 7.1e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM38317.1 - 2.2e-22 79.8 0.0 3.1e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM38317.1 - 5e-07 29.8 0.2 8.2e-07 29.1 0.2 1.3 1 0 0 1 1 1 1 KR domain Par3_HAL_N_term PF12053.8 GAM38317.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins Coat_F PF07875.12 GAM38317.1 - 0.18 12.1 0.1 0.36 11.1 0.1 1.5 1 0 0 1 1 1 0 Coat F domain Hydrolase_4 PF12146.8 GAM38318.1 - 3.1e-10 39.7 0.1 1e-09 38.1 0.1 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM38318.1 - 1.7e-08 35.3 0.7 2.9e-08 34.6 0.1 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM38318.1 - 8.5e-07 28.9 4.2 1.2e-05 25.1 2.2 2.9 2 2 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 GAM38318.1 - 0.033 13.7 0.1 3.7 7.0 0.0 2.7 2 1 1 3 3 3 0 Dienelactone hydrolase family FSH1 PF03959.13 GAM38318.1 - 0.054 13.1 0.9 0.62 9.7 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) SAM_2 PF07647.17 GAM38320.1 - 4.6e-12 45.9 0.0 9e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAM38320.1 - 1.2e-08 35.2 0.1 3.2e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 GAM38320.1 - 5.8e-08 33.2 0.2 5.8e-08 33.2 0.2 2.2 2 1 0 2 2 2 1 PH domain SAM_3 PF18016.1 GAM38320.1 - 2.1e-05 24.3 0.0 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 GAM38320.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PUMA PF15826.5 GAM38321.1 - 0.1 12.8 0.4 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis DDE_3 PF13358.6 GAM38322.1 - 1.7e-30 105.7 0.0 3.2e-30 104.8 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_33 PF13592.6 GAM38322.1 - 2.7e-07 30.1 0.4 8.7e-07 28.5 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix rve PF00665.26 GAM38322.1 - 0.00016 21.8 0.0 0.0012 19.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_ISAZ013 PF07592.11 GAM38322.1 - 0.086 11.8 0.0 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain CSF-1 PF05337.11 GAM38322.1 - 0.15 12.2 0.0 0.38 10.8 0.0 1.6 2 0 0 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) PNP_UDP_1 PF01048.20 GAM38323.1 - 1.2e-17 64.0 0.2 5.6e-17 61.8 0.1 2.2 2 1 0 2 2 2 1 Phosphorylase superfamily NB-ARC PF00931.22 GAM38323.1 - 2.5e-06 26.8 0.0 4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 GAM38323.1 - 0.0041 17.5 0.5 0.043 14.2 0.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain TPR_12 PF13424.6 GAM38324.1 - 2.1e-101 332.3 44.1 8.3e-21 74.1 1.3 5.3 1 1 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 GAM38324.1 - 1.8e-86 281.9 24.3 8.2e-14 50.9 0.7 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 GAM38324.1 - 1.1e-37 125.2 16.4 1.8e-05 24.4 0.1 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 GAM38324.1 - 9.2e-35 117.1 20.5 4.4e-05 23.1 0.0 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 GAM38324.1 - 6e-22 75.9 16.4 0.0028 17.6 0.1 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 GAM38324.1 - 4.7e-21 73.2 14.7 0.0031 17.6 0.0 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 GAM38324.1 - 2e-17 62.4 10.1 0.15 12.9 0.0 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_4 PF07721.14 GAM38324.1 - 2.7e-17 61.6 0.3 0.037 14.7 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_3 PF07720.12 GAM38324.1 - 1.7e-14 53.4 4.7 1.7 8.7 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAM38324.1 - 1.3e-13 51.3 21.0 0.0064 17.1 0.2 6.8 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 GAM38324.1 - 1.9e-11 43.5 6.5 0.38 11.2 0.0 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM38324.1 - 1.5e-10 41.0 16.9 3.3e-09 36.6 13.3 3.4 2 1 1 3 3 3 2 MalT-like TPR region NRBF2_MIT PF17169.4 GAM38324.1 - 4.7e-08 33.1 13.1 2.7 8.3 0.0 7.4 7 2 1 8 8 8 2 MIT domain of nuclear receptor-binding factor 2 ANAPC3 PF12895.7 GAM38324.1 - 5.6e-08 32.9 7.2 1 9.6 0.4 6.6 1 1 5 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAM38324.1 - 2.1e-06 28.1 20.1 0.029 14.9 1.3 5.5 2 1 4 7 7 6 4 Tetratricopeptide repeat DUF1925 PF09094.11 GAM38324.1 - 4e-05 23.8 7.3 2.8 8.3 0.1 5.8 3 2 3 6 6 6 1 Domain of unknown function (DUF1925) TPR_9 PF13371.6 GAM38324.1 - 0.00046 20.3 0.5 9.6 6.4 0.0 5.0 2 2 4 6 6 6 0 Tetratricopeptide repeat Atu4866 PF11512.8 GAM38324.1 - 0.00069 19.9 7.7 48 4.4 0.1 6.5 6 1 1 7 7 7 0 Agrobacterium tumefaciens protein Atu4866 TPR_11 PF13414.6 GAM38324.1 - 0.0032 17.1 23.5 1.4 8.6 0.4 7.9 8 0 0 8 8 8 1 TPR repeat DUF5112 PF17139.4 GAM38324.1 - 0.11 12.0 1.3 2 7.8 0.2 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF5112) Tcf25 PF04910.14 GAM38324.1 - 0.2 10.7 0.5 18 4.2 0.1 2.8 2 1 1 3 3 3 0 Transcriptional repressor TCF25 SoxG PF04268.12 GAM38324.1 - 0.44 10.7 1.7 9 6.4 0.1 2.8 2 1 2 4 4 3 0 Sarcosine oxidase, gamma subunit family Fungal_trans_2 PF11951.8 GAM38325.1 - 1.4e-96 323.7 0.0 1.8e-96 323.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain SHR3_chaperone PF08229.11 GAM38326.1 - 6.5e-78 260.0 0.0 7.6e-78 259.8 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 GAM38326.1 - 0.022 14.7 0.3 0.036 14.0 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5453) MFS_1 PF07690.16 GAM38326.1 - 0.048 12.6 3.8 0.078 11.9 3.9 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily Arrestin_N PF00339.29 GAM38327.1 - 7.9e-18 64.9 0.0 1.6e-16 60.6 0.0 3.1 4 1 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAM38327.1 - 2.4e-09 37.8 0.0 2.4e-05 24.8 0.0 3.3 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain WD40 PF00400.32 GAM38329.1 - 6.7e-19 67.9 12.9 0.0016 19.2 0.4 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM38329.1 - 4.2e-07 30.2 0.3 0.39 11.1 0.0 4.9 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PGA2 PF07543.12 GAM38330.1 - 0.85 9.6 12.3 4.3 7.3 0.3 3.1 2 1 1 3 3 3 0 Protein trafficking PGA2 Mnd1 PF03962.15 GAM38331.1 - 2.2e-21 75.9 0.2 7e-21 74.3 0.0 1.9 2 0 0 2 2 2 1 Mnd1 HTH domain DUF3584 PF12128.8 GAM38331.1 - 0.001 16.7 11.3 0.0014 16.2 11.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4407 PF14362.6 GAM38331.1 - 0.15 11.4 6.2 0.19 11.1 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 GAM38331.1 - 0.21 10.4 1.7 0.24 10.2 1.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DASH_Dad4 PF08650.10 GAM38331.1 - 0.63 10.1 3.4 5.1 7.1 0.6 2.7 3 0 0 3 3 3 0 DASH complex subunit Dad4 DUF1664 PF07889.12 GAM38331.1 - 2.4 8.2 7.4 3 7.9 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 GAM38331.1 - 2.6 8.8 8.3 3.1 8.5 4.1 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) CENP-H PF05837.12 GAM38331.1 - 3 8.3 12.9 8.6 6.8 0.1 2.8 1 1 2 3 3 3 0 Centromere protein H (CENP-H) OmpH PF03938.14 GAM38331.1 - 3.9 7.8 15.3 12 6.2 15.5 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ABC_membrane PF00664.23 GAM38336.1 - 4.7e-54 183.9 42.4 1.7e-35 123.0 20.3 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 GAM38336.1 - 1.1e-49 168.5 0.1 1.2e-29 103.5 0.2 2.9 2 0 0 2 2 2 2 ABC transporter Zeta_toxin PF06414.12 GAM38336.1 - 5.9e-06 25.7 0.0 0.0033 16.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.23 GAM38336.1 - 1.2e-05 25.3 0.5 0.022 14.8 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 GAM38336.1 - 0.00011 21.7 4.8 0.76 9.2 1.9 3.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAM38336.1 - 0.00019 21.4 4.6 0.74 9.6 0.4 3.6 2 2 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM38336.1 - 0.00025 20.7 1.7 0.55 10.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM38336.1 - 0.00041 20.8 1.3 1.5 9.2 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAM38336.1 - 0.00093 19.1 1.6 0.47 10.3 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 GAM38336.1 - 0.0038 17.8 7.2 0.34 11.4 0.6 3.5 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 GAM38336.1 - 0.014 15.7 3.2 2 8.7 0.0 3.5 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 GAM38336.1 - 0.021 14.9 2.6 0.31 11.1 0.3 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 GAM38336.1 - 0.037 14.6 1.6 3.9 8.0 0.0 3.2 3 1 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 GAM38336.1 - 0.074 13.0 0.2 13 5.6 0.1 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Roc PF08477.13 GAM38336.1 - 0.11 12.7 0.3 23 5.3 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 GAM38336.1 - 0.11 12.1 3.8 4.6 6.9 0.2 2.8 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 GAM38336.1 - 0.16 10.8 1.2 3.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 GAM38336.1 - 0.27 11.3 10.3 0.23 11.5 0.2 3.1 3 1 0 3 3 3 0 Dynamin family AAA_28 PF13521.6 GAM38336.1 - 0.46 10.7 5.6 0.52 10.5 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 GAM38336.1 - 0.49 10.1 5.8 5.4 6.6 0.2 2.7 3 0 0 3 3 3 0 AAA ATPase domain ATP_bind_1 PF03029.17 GAM38336.1 - 1.4 8.7 6.0 14 5.3 0.1 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Myb_DNA-bind_6 PF13921.6 GAM38337.1 - 0.63 10.3 3.3 1.4 9.2 2.2 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain Ank_2 PF12796.7 GAM38338.1 - 5.6e-83 273.6 20.8 3.2e-14 53.3 0.1 8.0 2 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM38338.1 - 1.7e-50 168.7 12.6 2.1e-06 28.2 0.0 9.9 6 4 4 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM38338.1 - 8.4e-44 147.1 13.3 1.8e-06 28.1 0.0 11.3 5 4 6 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.30 GAM38338.1 - 1.1e-37 126.9 22.2 1.3e-06 28.5 0.7 13.2 13 1 1 14 14 13 8 Ankyrin repeat Ank_3 PF13606.6 GAM38338.1 - 2.3e-37 122.7 12.7 7.5e-05 22.8 0.1 14.4 15 0 0 15 15 14 6 Ankyrin repeat NACHT PF05729.12 GAM38338.1 - 3.4e-12 46.6 0.0 9.2e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NACHT_N PF17100.5 GAM38338.1 - 5.8e-12 45.9 1.0 5.8e-12 45.9 1.0 2.0 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase AAA_16 PF13191.6 GAM38338.1 - 0.0012 19.2 0.0 0.006 17.0 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 GAM38338.1 - 0.0087 15.3 0.0 0.054 12.7 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.9 GAM38338.1 - 0.0097 15.2 0.3 0.2 10.8 0.0 2.6 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 GAM38338.1 - 0.02 15.3 0.1 0.11 12.9 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 GAM38338.1 - 0.03 14.6 0.0 0.14 12.5 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 GAM38338.1 - 0.037 14.1 0.1 3.9 7.5 0.0 3.4 2 1 1 3 3 3 0 AAA domain PPV_E1_C PF00519.17 GAM38338.1 - 0.055 12.3 0.0 0.71 8.6 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase DNA_pol_phi PF04931.13 GAM38338.1 - 0.31 9.1 14.6 0.67 8.0 14.6 1.4 1 0 0 1 1 1 0 DNA polymerase phi SnoaL PF07366.12 GAM38339.1 - 1.3e-20 73.5 0.0 1.6e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 GAM38339.1 - 1.5e-13 51.3 0.0 2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Aminotran_3 PF00202.21 GAM38340.1 - 2.4e-113 378.8 0.0 2.8e-113 378.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 GAM38340.1 - 0.022 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Glyco_transf_22 PF03901.17 GAM38341.1 - 3.1e-79 267.2 13.9 3.8e-79 266.9 13.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ArfGap PF01412.18 GAM38342.1 - 3.3e-37 127.1 0.1 1.1e-36 125.5 0.1 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3543 PF12063.8 GAM38344.1 - 4.8e-98 327.5 0.0 7.4e-98 326.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) ERAP1_C PF11838.8 GAM38344.1 - 7.5e-88 295.1 0.9 7.5e-88 295.1 0.9 2.8 3 0 0 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 GAM38344.1 - 1.3e-85 286.4 0.7 2.1e-85 285.7 0.7 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Pkinase PF00069.25 GAM38344.1 - 1.1e-60 205.2 0.0 1.9e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Peptidase_M1_N PF17900.1 GAM38344.1 - 9.6e-53 179.1 0.6 2.2e-52 178.0 0.6 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Pkinase_Tyr PF07714.17 GAM38344.1 - 1.5e-40 139.1 0.0 2.6e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2808 PF10989.8 GAM38344.1 - 0.14 12.1 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) COesterase PF00135.28 GAM38346.1 - 4.3e-09 35.8 0.2 2e-07 30.3 0.2 2.0 1 1 1 2 2 2 2 Carboxylesterase family zf-C2H2 PF00096.26 GAM38347.1 - 3.8e-12 45.9 14.2 1.5e-06 28.3 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM38347.1 - 2.1e-07 31.2 12.1 0.0024 18.6 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAM38347.1 - 2.7e-06 27.6 6.1 2.7e-06 27.6 6.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 GAM38347.1 - 1.5e-05 25.1 4.1 0.011 16.0 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAM38347.1 - 0.00026 21.3 5.5 0.0073 16.7 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 GAM38347.1 - 0.00088 19.2 11.5 0.018 15.1 2.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 GAM38347.1 - 0.035 13.7 5.5 1.3 8.8 0.4 2.5 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 GAM38347.1 - 0.27 11.2 2.7 15 5.6 0.3 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger RR_TM4-6 PF06459.12 GAM38347.1 - 0.48 10.2 2.7 0.87 9.4 2.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-C2H2_3rep PF18868.1 GAM38347.1 - 0.59 10.8 3.7 4.1 8.1 0.3 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 GAM38347.1 - 0.69 10.4 7.2 70 4.0 7.3 2.5 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 GAM38347.1 - 1.5 9.2 4.8 12 6.3 0.4 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 GAM38347.1 - 1.6 8.5 9.3 8.5 6.2 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 GAM38347.1 - 2.1 8.4 6.4 0.75 9.9 2.4 2.1 1 1 1 2 2 2 0 BED zinc finger Diphthami_syn_2 PF01902.17 GAM38348.1 - 3.9e-18 65.8 0.0 8.1e-12 45.1 0.0 3.7 2 2 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 GAM38348.1 - 4.7e-18 65.4 0.0 3.6e-10 39.9 0.0 3.6 4 0 0 4 4 4 2 Endoribonuclease L-PSP YqcI_YcgG PF08892.11 GAM38348.1 - 0.17 11.7 0.1 1 9.1 0.0 2.1 2 0 0 2 2 2 0 YqcI/YcgG family Glyoxalase PF00903.25 GAM38350.1 - 0.0019 18.4 0.3 0.0022 18.2 0.3 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyco_hydro_115 PF15979.5 GAM38350.1 - 0.18 11.2 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 115 Cupin_2 PF07883.11 GAM38351.1 - 9.4e-06 25.3 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 GAM38351.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 GAM38351.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ FAD_binding_3 PF01494.19 GAM38352.1 - 1.2e-43 149.7 0.0 1.5e-43 149.4 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM38352.1 - 1.9e-06 27.3 1.0 0.0014 17.9 0.3 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM38352.1 - 1.8e-05 25.2 0.2 0.0067 17.0 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM38352.1 - 4e-05 22.5 0.3 0.00049 18.9 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 GAM38352.1 - 0.00015 21.9 0.3 0.00035 20.7 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAM38352.1 - 0.00069 18.8 0.5 0.0068 15.5 0.3 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 GAM38352.1 - 0.00073 18.5 1.2 0.16 10.8 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 GAM38352.1 - 0.0018 17.6 0.1 0.0033 16.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 GAM38352.1 - 0.0028 17.6 0.9 0.62 10.1 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 GAM38352.1 - 0.0052 15.9 0.8 0.012 14.7 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 GAM38352.1 - 0.027 13.7 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM38352.1 - 0.056 13.0 3.2 0.054 13.1 1.1 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAM38352.1 - 0.062 12.6 0.5 20 4.3 0.1 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Fungal_trans PF04082.18 GAM38353.1 - 7.1e-17 61.3 0.8 1.2e-16 60.5 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.18 GAM38354.1 - 3.7e-62 209.8 0.0 4.9e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TRI12 PF06609.13 GAM38355.1 - 1.5e-52 178.8 20.7 2e-52 178.5 20.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 GAM38355.1 - 3.5e-22 78.8 40.0 3.5e-22 78.8 40.0 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM38355.1 - 1.8e-05 23.8 13.3 1.8e-05 23.8 13.3 3.0 3 1 1 4 4 4 1 Sugar (and other) transporter Pox_A14 PF05767.12 GAM38355.1 - 0.054 13.7 7.5 1.9 8.7 0.1 3.2 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 ESSS PF10183.9 GAM38355.1 - 0.39 11.0 1.4 7.6 6.8 0.0 2.7 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) adh_short PF00106.25 GAM38356.1 - 2e-33 115.5 0.0 3e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM38356.1 - 6.4e-27 94.6 0.0 9.5e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM38356.1 - 0.013 15.4 1.2 1.1 9.2 0.7 2.8 2 1 0 2 2 2 0 KR domain Epimerase PF01370.21 GAM38356.1 - 0.059 12.8 0.0 0.92 8.9 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Amidohydro_2 PF04909.14 GAM38357.1 - 4.1e-41 141.7 0.1 4.9e-41 141.4 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase AMP-binding PF00501.28 GAM38358.1 - 4e-41 141.0 0.0 5.5e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 GAM38358.1 - 0.00013 21.8 0.0 0.00029 20.7 0.0 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 GAM38358.1 - 0.034 15.1 0.0 0.087 13.8 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain PITH PF06201.13 GAM38359.1 - 2.6e-35 121.9 0.1 4.1e-35 121.2 0.1 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 GAM38359.1 - 3.4e-28 97.7 0.0 6.8e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 GAM38359.1 - 8.8e-06 25.3 0.0 2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 GAM38359.1 - 1.5e-05 25.2 0.1 7e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 GAM38359.1 - 1.7e-05 25.2 0.2 6.2e-05 23.4 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 GAM38359.1 - 0.00013 21.7 0.2 0.33 10.7 0.0 2.4 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.21 GAM38359.1 - 0.0009 19.2 0.3 0.013 15.4 0.2 2.2 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.6 GAM38359.1 - 0.0032 17.2 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 GAM38359.1 - 0.036 13.9 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.11 GAM38359.1 - 0.039 13.9 0.0 0.15 12.0 0.0 2.0 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE NIF PF03031.18 GAM38359.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Podoplanin PF05808.11 GAM38359.1 - 0.14 12.3 6.3 3 7.9 6.3 2.6 1 1 0 1 1 1 0 Podoplanin Thioredoxin_7 PF13899.6 GAM38359.1 - 0.14 12.4 0.1 0.38 11.0 0.1 1.7 1 0 0 1 1 1 0 Thioredoxin-like zf-CSL PF05207.13 GAM38360.1 - 5.8e-20 70.8 0.6 9.6e-20 70.1 0.6 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 GAM38360.1 - 4.2e-13 49.2 0.1 9.2e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4690 PF15756.5 GAM38360.1 - 1 10.0 5.8 0.17 12.5 1.2 2.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage peroxidase PF00141.23 GAM38361.1 - 4.9e-48 163.8 0.0 7.5e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DEAD PF00270.29 GAM38362.1 - 2.8e-47 160.8 0.0 1.7e-46 158.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM38362.1 - 1.8e-29 102.3 0.0 1.3e-28 99.5 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2986 PF11661.8 GAM38362.1 - 0.0029 18.1 2.4 0.013 16.0 2.4 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) ResIII PF04851.15 GAM38362.1 - 0.0036 17.3 0.0 0.0085 16.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3334 PF11813.8 GAM38362.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) SnoaL_4 PF13577.6 GAM38363.1 - 6.6e-08 32.7 0.0 8.2e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Ank_2 PF12796.7 GAM38364.1 - 1.6e-18 67.1 4.4 2.5e-12 47.2 0.6 3.3 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM38364.1 - 9.8e-17 61.1 0.7 1.1e-06 29.1 0.1 4.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM38364.1 - 1.2e-15 56.0 7.8 0.021 15.3 0.1 6.5 5 1 1 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 GAM38364.1 - 5.1e-12 45.8 7.5 0.0043 17.3 0.2 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 GAM38364.1 - 1.4e-07 31.6 7.6 0.03 14.8 0.1 5.3 6 0 0 6 6 6 3 Ankyrin repeat Stomoxyn PF11585.8 GAM38364.1 - 0.073 13.1 1.3 0.13 12.3 1.3 1.4 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn TPR_14 PF13428.6 GAM38365.1 - 2.2e-08 34.2 9.8 0.053 14.4 0.1 8.2 6 3 2 8 8 8 2 Tetratricopeptide repeat Suf PF05843.14 GAM38365.1 - 9.3e-05 22.6 0.1 9.3e-05 22.6 0.1 3.0 2 2 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_17 PF13431.6 GAM38365.1 - 0.1 13.0 0.1 44 4.8 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Gla PF00594.20 GAM38365.1 - 1.5 9.1 0.0 1.5 9.1 0.0 4.5 5 0 0 5 5 5 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Mitoc_mL59 PF18126.1 GAM38366.1 - 9.7e-47 158.5 10.4 3.1e-46 156.9 10.4 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 HetR_C PF18460.1 GAM38366.1 - 0.15 12.0 0.8 0.35 10.8 0.2 1.8 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain MOSC PF03473.17 GAM38367.1 - 6.5e-31 107.1 0.0 1.1e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 GAM38367.1 - 4.1e-22 78.3 0.0 8.9e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 GAM38367.1 - 2e-17 63.2 0.0 1e-07 31.2 0.0 2.9 2 1 0 2 2 2 2 Aminotransferase class-V MARVEL PF01284.23 GAM38368.1 - 0.0031 17.6 19.5 0.0041 17.1 19.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain SelK_SelG PF10961.8 GAM38368.1 - 0.079 13.6 0.1 0.079 13.6 0.1 2.6 2 1 1 3 3 3 0 Selenoprotein SelK_SelG RseC_MucC PF04246.12 GAM38368.1 - 3.3 7.7 5.4 3.1 7.8 2.1 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC PAP2 PF01569.21 GAM38369.1 - 2.9e-11 43.3 0.5 4.1e-11 42.8 0.5 1.2 1 0 0 1 1 1 1 PAP2 superfamily SLATT_1 PF18181.1 GAM38369.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 PAP2_3 PF14378.6 GAM38369.1 - 0.12 12.1 1.3 0.18 11.5 1.3 1.2 1 0 0 1 1 1 0 PAP2 superfamily NGP1NT PF08153.12 GAM38371.1 - 3.2e-50 169.6 0.0 5.2e-50 169.0 0.0 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 GAM38371.1 - 1.2e-17 64.1 0.0 7.8e-14 51.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM38371.1 - 5.6e-06 26.0 0.0 8.5e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAM38371.1 - 0.00019 21.4 0.0 0.00044 20.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 GAM38371.1 - 0.00074 19.0 0.0 0.16 11.4 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 GAM38371.1 - 0.0013 18.8 0.1 1.2 9.2 0.0 3.5 2 1 1 3 3 3 1 Dynamin family Roc PF08477.13 GAM38371.1 - 0.1 12.8 0.0 25 5.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SDA1 PF05285.12 GAM38371.1 - 1.2 8.5 20.7 0.038 13.4 14.7 1.5 2 0 0 2 2 2 0 SDA1 Pkinase PF00069.25 GAM38372.1 - 3.7e-37 128.1 0.0 7.2e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM38372.1 - 5.7e-27 94.6 0.0 1.1e-26 93.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.18 GAM38372.1 - 1.8e-06 27.5 1.2 7.5e-06 25.5 1.2 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Kinase-like PF14531.6 GAM38372.1 - 0.004 16.5 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM38372.1 - 0.028 13.8 0.0 0.073 12.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 GAM38372.1 - 0.054 12.5 0.0 0.095 11.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase EnY2 PF10163.9 GAM38372.1 - 0.13 12.6 0.7 0.38 11.2 0.7 1.8 1 0 0 1 1 1 0 Transcription factor e(y)2 Prefoldin_3 PF13758.6 GAM38373.1 - 1.7e-34 117.8 3.0 5e-34 116.3 3.0 1.9 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 GAM38373.1 - 3.7e-21 75.7 1.4 3.7e-21 75.7 1.4 4.9 4 2 0 4 4 4 2 Domain of unknown function (DUF3835) MAT1 PF06391.13 GAM38374.1 - 2.2e-42 145.2 9.1 2.8e-42 144.9 9.1 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 GAM38374.1 - 2e-30 104.4 8.1 2.9e-30 103.9 8.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM38374.1 - 0.00016 21.5 5.0 0.00028 20.7 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM38374.1 - 0.00037 20.3 3.1 0.00074 19.3 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM38374.1 - 0.00053 19.8 2.1 0.0013 18.6 2.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM38374.1 - 0.00081 19.3 7.2 0.013 15.5 7.8 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAM38374.1 - 0.0042 17.4 5.9 0.007 16.7 5.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 GAM38374.1 - 0.01 15.6 5.0 0.11 12.4 1.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 GAM38374.1 - 0.029 14.4 6.2 0.055 13.5 6.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 GAM38374.1 - 0.05 13.2 1.1 0.095 12.3 1.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 GAM38374.1 - 0.28 11.1 8.7 10 6.0 9.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF3797 PF12677.7 GAM38374.1 - 0.44 10.5 2.7 1 9.3 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) Cep57_MT_bd PF06657.13 GAM38375.1 - 1.8e-27 95.6 2.3 1.8e-27 95.6 2.3 3.7 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 GAM38375.1 - 7.3e-24 83.6 30.1 8.9e-23 80.2 9.8 4.4 3 0 0 3 3 3 2 Centrosome localisation domain of PPC89 HALZ PF02183.18 GAM38375.1 - 0.0064 16.7 1.4 0.0064 16.7 1.4 3.8 5 0 0 5 5 5 1 Homeobox associated leucine zipper Trp_halogenase PF04820.14 GAM38376.1 - 4.9e-26 91.6 0.8 5.7e-12 45.2 0.2 2.4 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 GAM38376.1 - 4.8e-13 49.1 0.0 8.1e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM38376.1 - 0.00019 20.8 0.0 0.00037 19.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM38376.1 - 0.00023 21.3 0.2 0.00058 20.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GAM38376.1 - 0.00085 18.8 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 GAM38376.1 - 0.0016 18.1 1.0 0.016 14.8 0.3 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 GAM38376.1 - 0.0033 16.6 0.1 0.0061 15.7 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAM38376.1 - 0.017 14.2 0.1 0.045 12.8 0.1 1.7 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 GAM38376.1 - 0.027 13.2 0.1 0.071 11.8 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.6 GAM38376.1 - 0.14 12.7 0.1 1.1 9.8 0.0 2.3 3 0 0 3 3 3 0 Putative NAD(P)-binding DUF5628 PF18621.1 GAM38376.1 - 0.18 12.3 0.5 2.3 8.7 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5628) NmrA PF05368.13 GAM38377.1 - 1.6e-19 70.4 0.0 1.9e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM38377.1 - 1.6e-10 41.2 0.0 4e-10 39.9 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding DUF4974 PF16344.5 GAM38377.1 - 0.19 11.8 0.4 0.71 9.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) FAD_binding_3 PF01494.19 GAM38378.1 - 7.1e-14 51.8 2.1 2.9e-12 46.5 2.1 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM38378.1 - 0.0036 17.5 0.0 0.0078 16.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM38378.1 - 0.038 13.1 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 GAM38378.1 - 0.044 12.8 0.1 0.92 8.5 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein Methyltransf_2 PF00891.18 GAM38379.1 - 4.8e-24 84.8 0.0 6.3e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase domain Phage_cap_E PF03864.15 GAM38379.1 - 0.0054 15.9 0.1 0.0087 15.3 0.1 1.2 1 0 0 1 1 1 1 Phage major capsid protein E MFS_1 PF07690.16 GAM38381.1 - 1.8e-13 50.2 57.7 3.9e-08 32.6 43.6 3.7 2 1 1 3 3 3 2 Major Facilitator Superfamily ketoacyl-synt PF00109.26 GAM38382.1 - 1e-78 264.5 0.0 1.9e-78 263.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 GAM38382.1 - 9.2e-48 163.1 4.3 1.9e-47 162.1 1.5 2.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 GAM38382.1 - 4.6e-42 144.6 0.0 8.6e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM38382.1 - 1.4e-32 112.1 0.6 3e-32 111.1 0.6 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 GAM38382.1 - 9.6e-28 97.9 0.0 9.6e-27 94.6 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 GAM38382.1 - 4e-16 59.1 6.5 2e-07 31.3 0.3 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 GAM38382.1 - 5.4e-11 42.3 0.0 9e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 GAM38382.1 - 1.9e-08 34.7 0.1 6.6e-08 33.0 0.1 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 GAM38382.1 - 0.00016 22.4 0.0 0.042 14.5 0.0 3.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 GAM38382.1 - 0.013 14.9 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain MFS_1 PF07690.16 GAM38383.1 - 2.6e-36 125.3 32.2 2.6e-36 125.3 32.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM38383.1 - 3.9e-12 45.8 7.1 3.9e-12 45.8 7.1 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAM38383.1 - 9.6e-06 24.3 1.5 2e-05 23.2 1.5 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Nitroreductase PF00881.24 GAM38383.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Nitroreductase family DUF639 PF04842.12 GAM38383.1 - 0.28 10.6 1.9 0.59 9.5 1.9 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) TPR_10 PF13374.6 GAM38384.1 - 1.1e-07 31.5 0.3 3.9e-07 29.7 0.1 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM38384.1 - 1.2e-07 31.9 0.1 3.8e-07 30.3 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM38384.1 - 0.0041 16.9 0.0 0.013 15.2 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM38384.1 - 0.018 15.1 0.2 0.095 12.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM38384.1 - 0.032 14.3 0.0 0.09 12.8 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAM38384.1 - 0.053 13.9 1.2 1.9 9.0 0.2 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF5103 PF17116.5 GAM38384.1 - 0.11 11.8 0.1 1.3 8.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5103) TPR_14 PF13428.6 GAM38384.1 - 0.11 13.3 0.3 0.49 11.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SKG6 PF08693.10 GAM38385.1 - 0.034 13.6 0.6 0.057 12.8 0.6 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ABC_membrane PF00664.23 GAM38386.1 - 4.2e-70 236.5 36.3 6.4e-38 131.0 10.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM38386.1 - 7.7e-59 198.1 0.0 7.6e-30 104.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAM38386.1 - 3.4e-16 59.4 4.8 2.1e-07 30.6 0.4 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAM38386.1 - 2.2e-11 44.1 0.1 0.36 10.6 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAM38386.1 - 1.1e-08 35.2 0.1 0.00037 20.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 GAM38386.1 - 4.2e-08 32.8 3.3 0.0024 17.6 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM38386.1 - 1.2e-07 32.3 0.1 0.0099 16.3 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAM38386.1 - 2e-07 31.4 0.7 0.19 12.0 0.1 5.0 4 1 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.23 GAM38386.1 - 2.5e-07 30.8 0.1 0.00074 19.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 GAM38386.1 - 9.9e-06 26.2 0.4 0.084 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GAM38386.1 - 1.2e-05 25.2 0.5 0.091 12.5 0.0 4.0 2 2 1 3 3 3 2 AAA domain AAA_25 PF13481.6 GAM38386.1 - 0.0001 21.9 0.2 1.5 8.3 0.0 3.9 4 0 0 4 4 4 2 AAA domain cobW PF02492.19 GAM38386.1 - 0.00024 20.7 0.1 0.031 13.9 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 GAM38386.1 - 0.00026 19.9 6.2 0.26 10.0 0.1 3.9 4 1 0 4 4 4 2 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.18 GAM38386.1 - 0.00087 18.7 0.0 0.69 9.2 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family Dynamin_N PF00350.23 GAM38386.1 - 0.0019 18.3 0.0 0.82 9.7 0.0 2.5 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 GAM38386.1 - 0.0021 18.2 3.9 0.37 10.9 0.3 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_15 PF13175.6 GAM38386.1 - 0.0033 17.2 1.7 1.2 8.7 0.0 2.5 3 0 0 3 3 2 1 AAA ATPase domain IstB_IS21 PF01695.17 GAM38386.1 - 0.0038 17.0 0.1 1.2 8.8 0.0 3.7 4 0 0 4 4 4 1 IstB-like ATP binding protein SbcCD_C PF13558.6 GAM38386.1 - 0.0041 17.3 0.9 1 9.6 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 GAM38386.1 - 0.0061 16.4 0.2 4.9 6.9 0.1 3.0 3 1 0 3 3 3 1 DEAD/DEAH box helicase Septin PF00735.18 GAM38386.1 - 0.013 14.8 0.0 0.31 10.3 0.0 2.2 2 0 0 2 2 2 0 Septin Zeta_toxin PF06414.12 GAM38386.1 - 0.014 14.7 0.0 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 GAM38386.1 - 0.015 15.4 0.2 5.3 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 GAM38386.1 - 0.03 13.2 0.7 2.8 6.8 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain AAA_18 PF13238.6 GAM38386.1 - 0.048 14.2 0.0 14 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 GAM38386.1 - 0.054 12.8 2.0 2.6 7.3 0.0 3.0 3 0 0 3 3 3 0 KaiC NACHT PF05729.12 GAM38386.1 - 0.057 13.3 0.0 9.6 6.1 0.0 3.1 3 0 0 3 3 3 0 NACHT domain AAA_7 PF12775.7 GAM38386.1 - 0.07 12.6 0.1 8.6 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 GAM38386.1 - 0.098 12.4 0.1 19 4.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 GAM38386.1 - 0.11 12.5 0.2 31 4.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 GAM38386.1 - 0.12 12.7 0.1 11 6.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 GAM38386.1 - 0.13 12.2 0.2 4.8 7.1 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF3987 PF13148.6 GAM38386.1 - 0.17 10.9 0.1 6 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Guanylate_kin PF00625.21 GAM38386.1 - 0.19 11.4 0.1 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase NTPase_1 PF03266.15 GAM38386.1 - 2.1 8.2 3.5 20 5.0 0.1 3.2 3 0 0 3 3 3 0 NTPase Polysacc_synt_4 PF04669.13 GAM38387.1 - 5.2e-24 84.8 1.6 1.5e-22 80.1 1.6 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Ric8 PF10165.9 GAM38388.1 - 1.5e-106 357.2 0.1 2.6e-106 356.4 0.0 1.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor synembryn MFS_1 PF07690.16 GAM38389.1 - 4e-09 35.9 28.5 1.1e-08 34.4 28.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 GAM38391.1 - 1.6e-31 109.6 67.9 5.3e-27 94.7 44.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Rif1_N PF12231.8 GAM38392.1 - 5e-137 456.9 1.6 5e-137 456.9 1.6 2.1 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Glyoxalase_6 PF18029.1 GAM38393.1 - 7.1e-07 30.0 0.0 9.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 GAM38393.1 - 0.12 12.5 0.0 2 8.6 0.0 2.1 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Abhydrolase_1 PF00561.20 GAM38394.1 - 5e-13 49.3 0.0 1.4e-10 41.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM38394.1 - 2.6e-10 41.3 0.0 3.3e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM38394.1 - 1.7e-08 34.0 0.0 1.5e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 GAM38394.1 - 1.1e-07 30.9 0.0 1.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.11 GAM38394.1 - 0.0078 16.2 0.0 16 5.3 0.0 3.0 3 0 0 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal DAHP_synth_2 PF01474.16 GAM38395.1 - 8.9e-203 673.7 0.0 1e-202 673.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family UBA_4 PF14555.6 GAM38396.1 - 0.011 15.5 0.2 0.029 14.2 0.0 1.8 2 0 0 2 2 2 0 UBA-like domain Aldose_epim PF01263.20 GAM38397.1 - 2.1e-39 135.7 0.3 1.3e-38 133.1 0.1 2.0 1 1 1 2 2 2 2 Aldose 1-epimerase MFS_1 PF07690.16 GAM38397.1 - 4.2e-22 78.5 20.2 4.2e-22 78.5 20.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM38397.1 - 0.00077 18.4 1.0 0.0015 17.5 1.0 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter WND PF07861.11 GAM38397.1 - 0.039 13.4 0.2 0.062 12.7 0.2 1.2 1 0 0 1 1 1 0 WisP family N-Terminal Region Epimerase PF01370.21 GAM38398.1 - 6.3e-17 61.8 0.0 9e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM38398.1 - 2.4e-06 27.2 0.0 8.5e-06 25.4 0.0 1.9 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GAM38398.1 - 6.4e-05 22.2 0.0 9.1e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 GAM38398.1 - 0.0011 18.0 0.0 0.0025 16.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2935 PF11155.8 GAM38399.1 - 0.018 15.4 0.0 0.025 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) FlaC_arch PF05377.11 GAM38399.1 - 0.055 13.9 0.3 0.82 10.1 0.2 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DnaG_DnaB_bind PF08278.11 GAM38399.1 - 0.1 13.2 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding TMPIT PF07851.13 GAM38399.1 - 0.18 11.0 0.0 0.18 11.0 0.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein ABC_tran_CTD PF16326.5 GAM38399.1 - 0.19 12.0 5.9 6.7 7.0 2.3 2.4 2 1 0 2 2 2 0 ABC transporter C-terminal domain FliT PF05400.13 GAM38399.1 - 0.28 12.0 2.1 1.8 9.4 2.1 2.0 1 1 0 1 1 1 0 Flagellar protein FliT Mating_C PF12737.7 GAM38400.1 - 0.03 13.6 0.6 0.037 13.3 0.6 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Dak2 PF02734.17 GAM38401.1 - 0.034 14.0 1.7 0.04 13.8 1.7 1.1 1 0 0 1 1 1 0 DAK2 domain ExsD PF16806.5 GAM38401.1 - 0.055 13.4 0.3 0.065 13.1 0.3 1.1 1 0 0 1 1 1 0 Antiactivator protein ExsD Ribosomal_S5 PF00333.20 GAM38401.1 - 0.16 11.9 2.2 0.98 9.5 2.2 2.1 1 1 0 1 1 1 0 Ribosomal protein S5, N-terminal domain PSK_trans_fac PF07704.11 GAM38401.1 - 0.7 10.7 4.7 2.5 8.9 4.7 1.8 1 1 0 1 1 1 0 Rv0623-like transcription factor But2 PF09792.9 GAM38403.1 - 5.2e-52 176.0 3.8 8.2e-52 175.4 3.8 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain SGL PF08450.12 GAM38404.1 - 2e-68 230.6 0.1 3e-68 230.1 0.1 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Phosphodiest PF01663.22 GAM38404.1 - 0.007 16.0 0.1 0.0097 15.5 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Arylesterase PF01731.20 GAM38404.1 - 0.031 14.5 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 Arylesterase PQQ_3 PF13570.6 GAM38404.1 - 0.067 13.7 0.1 23 5.7 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain Reg_prop PF07494.11 GAM38404.1 - 0.073 13.3 0.8 27 5.4 0.2 2.8 2 0 0 2 2 2 0 Two component regulator propeller Phytase-like PF13449.6 GAM38404.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 Esterase-like activity of phytase Involucrin2 PF06994.11 GAM38405.1 - 0.061 13.4 7.2 0.14 12.2 7.2 1.6 1 0 0 1 1 1 0 Involucrin Nup54 PF13874.6 GAM38405.1 - 7.2 6.7 11.2 20 5.3 0.5 2.8 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 His_Phos_2 PF00328.22 GAM38406.1 - 1.7e-60 205.4 0.0 2.2e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ribophorin_II PF05817.14 GAM38408.1 - 1.6e-26 93.1 0.0 2.2e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Sulfatase PF00884.23 GAM38409.1 - 1.3e-21 77.3 0.0 2.5e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 GAM38409.1 - 6.7e-06 25.0 0.0 9.9e-06 24.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 GAM38409.1 - 0.00027 20.6 0.0 0.00043 20.0 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Isochorismatase PF00857.20 GAM38410.1 - 1.3e-38 132.9 0.1 1.5e-38 132.7 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family adh_short_C2 PF13561.6 GAM38411.1 - 4.7e-57 193.2 0.5 5.5e-57 193.0 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM38411.1 - 1.5e-45 155.0 3.3 2e-45 154.6 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM38411.1 - 3.9e-14 53.0 0.5 5.6e-14 52.4 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM38411.1 - 0.0098 15.4 0.1 0.013 14.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PLA2_B PF01735.18 GAM38412.1 - 1.8e-186 620.3 4.0 2.2e-186 620.1 4.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PSD3 PF07626.11 GAM38412.1 - 0.023 15.2 0.1 13 6.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1587) ABC_tran PF00005.27 GAM38413.1 - 1.4e-37 129.2 4.4 1.9e-19 70.5 0.0 3.5 4 0 0 4 4 3 2 ABC transporter ABC_membrane PF00664.23 GAM38413.1 - 6e-17 62.2 15.6 6e-17 62.2 15.6 3.0 2 1 1 3 3 3 1 ABC transporter transmembrane region AAA_21 PF13304.6 GAM38413.1 - 8.6e-12 45.5 1.5 0.011 15.5 0.0 4.5 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM38413.1 - 9.6e-07 28.5 1.5 0.48 9.8 0.1 4.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM38413.1 - 6.3e-06 25.8 0.1 0.18 11.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GAM38413.1 - 7.5e-05 23.0 0.0 0.85 9.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 GAM38413.1 - 0.00083 19.4 0.1 0.48 10.5 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 GAM38413.1 - 0.0019 17.3 0.0 1.6 7.7 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_7 PF12775.7 GAM38413.1 - 0.0024 17.4 0.0 0.71 9.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 GAM38413.1 - 0.0064 16.7 0.0 0.38 10.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 GAM38413.1 - 0.01 15.7 0.2 3.7 7.4 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 GAM38413.1 - 0.013 15.9 0.0 7 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 GAM38413.1 - 0.014 15.9 4.3 2.8 8.5 0.0 3.8 3 1 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 GAM38413.1 - 0.019 14.3 0.1 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.6 GAM38413.1 - 0.036 13.8 7.1 1.9 8.1 0.1 3.3 3 0 0 3 3 2 0 AAA ATPase domain Dynamin_N PF00350.23 GAM38413.1 - 0.098 12.7 6.3 1.8 8.6 0.0 3.6 3 0 0 3 3 3 0 Dynamin family AAA_23 PF13476.6 GAM38413.1 - 0.39 11.2 8.3 3.1 8.2 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 GAM38413.1 - 0.61 10.5 2.5 47 4.4 0.0 3.4 5 0 0 5 5 3 0 ATPase family associated with various cellular activities (AAA) Scytalone_dh PF02982.14 GAM38414.1 - 4.9e-51 172.7 0.4 5.4e-51 172.5 0.4 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 GAM38414.1 - 2.7e-05 24.3 0.2 3.6e-05 23.9 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain PhageMin_Tail PF10145.9 GAM38415.1 - 0.79 9.5 10.7 0.84 9.5 1.1 2.1 2 0 0 2 2 2 0 Phage-related minor tail protein SepZ PF06066.11 GAM38415.1 - 1.1 9.5 7.9 0.32 11.2 2.3 2.2 2 0 0 2 2 2 0 SepZ Transp_cyt_pur PF02133.15 GAM38416.1 - 1.6e-101 340.3 47.4 1.8e-101 340.1 47.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.12 GAM38417.1 - 1.8e-116 388.8 0.2 3.7e-116 387.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 GAM38417.1 - 2e-28 99.5 5.6 8.8e-23 81.0 0.8 3.6 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GAM38417.1 - 6.8e-26 91.0 9.9 9.2e-26 90.6 0.1 3.1 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 GAM38417.1 - 0.00046 18.9 2.7 0.39 9.3 0.9 2.4 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 GAM38417.1 - 0.011 15.3 0.3 0.011 15.3 0.3 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 GAM38417.1 - 0.017 14.6 0.1 0.046 13.2 0.1 1.7 1 0 0 1 1 1 0 ROK family DUF4283 PF14111.6 GAM38417.1 - 0.2 11.2 0.0 0.51 9.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) FtsA PF14450.6 GAM38417.1 - 2.5 8.6 4.9 12 6.4 0.4 3.5 3 2 0 3 3 3 0 Cell division protein FtsA Response_reg PF00072.24 GAM38418.1 - 1.2e-23 83.4 0.1 2.7e-23 82.3 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 GAM38418.1 - 1.5e-16 60.9 0.0 3.4e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GAM38418.1 - 3.7e-12 46.1 0.0 1.3e-11 44.4 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF4964 PF16334.5 GAM38418.1 - 0.046 13.3 0.1 0.15 11.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) Epimerase PF01370.21 GAM38419.1 - 1.4e-15 57.5 0.0 3.4e-15 56.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM38419.1 - 1.1e-14 54.1 0.0 2.2e-14 53.1 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAM38419.1 - 2.4e-11 43.9 0.0 3.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 GAM38419.1 - 5.7e-10 38.8 0.0 3.7e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 GAM38419.1 - 1.5e-08 34.5 0.0 5e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAM38419.1 - 1.9e-08 34.2 0.1 4.6e-08 32.9 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 GAM38419.1 - 1.4e-06 27.7 0.0 1.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 GAM38419.1 - 0.0023 18.2 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 GAM38419.1 - 0.0041 16.6 0.1 0.0085 15.6 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 GAM38419.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 GAM38419.1 - 0.057 13.3 0.3 0.55 10.1 0.3 2.1 1 1 0 1 1 1 0 KR domain DUF4797 PF16051.5 GAM38419.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4797) Mac PF12464.8 GAM38420.1 - 3.3e-15 56.1 0.0 6.9e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 GAM38420.1 - 1.5e-13 49.8 7.1 3.1e-11 42.5 3.6 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAM38420.1 - 5.9e-12 45.1 6.1 3.7e-09 36.2 3.6 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Filament PF00038.21 GAM38420.1 - 0.018 14.7 1.1 0.028 14.0 1.1 1.3 1 0 0 1 1 1 0 Intermediate filament protein DUF2353 PF09789.9 GAM38420.1 - 0.018 14.4 0.5 0.021 14.2 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Taxilin PF09728.9 GAM38420.1 - 0.035 13.3 0.5 0.061 12.5 0.5 1.4 1 1 0 1 1 1 0 Myosin-like coiled-coil protein CCDC106 PF15794.5 GAM38420.1 - 0.064 13.0 0.4 0.1 12.3 0.3 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 ACT_6 PF13740.6 GAM38420.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 ACT domain DUF1664 PF07889.12 GAM38420.1 - 0.17 11.9 0.3 0.27 11.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CART PF06373.11 GAM38420.1 - 0.31 11.3 0.6 7.2 6.9 0.1 2.9 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) Beta-lactamase PF00144.24 GAM38421.1 - 5.1e-28 98.3 0.0 9e-20 71.2 0.0 3.0 1 1 1 2 2 2 2 Beta-lactamase Kelch_4 PF13418.6 GAM38422.1 - 1.5e-21 76.1 0.6 2.1e-07 30.8 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM38422.1 - 3.6e-16 58.5 0.7 0.0002 20.9 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 GAM38422.1 - 6.4e-14 51.7 8.1 3.5e-05 23.9 0.3 4.9 3 1 1 4 4 4 4 Kelch motif Kelch_2 PF07646.15 GAM38422.1 - 2.9e-13 49.2 2.6 0.00012 21.9 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 GAM38422.1 - 8.4e-12 45.1 15.9 1e-08 35.3 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM38422.1 - 7.7e-11 41.7 6.4 3.7e-05 23.6 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Epimerase PF01370.21 GAM38423.1 - 2.5e-05 23.8 0.1 0.00016 21.2 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAM38423.1 - 0.00014 21.1 0.0 0.0037 16.5 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 GAM38423.1 - 0.012 15.2 0.2 0.17 11.4 0.1 2.4 2 2 0 2 2 2 0 NmrA-like family GDP_Man_Dehyd PF16363.5 GAM38423.1 - 0.081 12.3 0.7 1.2 8.5 0.0 2.4 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase AhpC-TSA PF00578.21 GAM38424.1 - 5e-31 107.2 0.0 8.2e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAM38424.1 - 9.3e-15 54.6 0.0 1.3e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 GAM38424.1 - 1.1e-12 47.6 0.6 1.7e-12 46.9 0.6 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MFS_1 PF07690.16 GAM38425.1 - 3.6e-40 138.0 27.6 3.6e-40 138.0 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM38425.1 - 6.5e-08 31.9 4.2 6.5e-08 31.9 4.2 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAM38425.1 - 0.00017 20.2 2.4 0.00028 19.5 2.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EVE PF01878.18 GAM38426.1 - 4e-50 169.6 0.2 8.3e-50 168.6 0.2 1.6 1 0 0 1 1 1 1 EVE domain HK97-gp10_like PF04883.12 GAM38426.1 - 3.4 8.7 7.8 8 7.5 3.1 2.8 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component RPA43_OB PF17875.1 GAM38426.1 - 5 7.8 12.1 6.7 7.4 3.0 3.1 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I Methyltransf_PK PF05891.12 GAM38427.1 - 1e-63 214.8 0.0 5.9e-40 137.1 0.0 3.2 2 1 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 GAM38427.1 - 7.7e-09 35.6 0.0 2.1e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM38427.1 - 0.012 16.3 0.0 1 10.1 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAM38427.1 - 0.021 15.4 0.0 0.68 10.6 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain CDC45 PF02724.14 GAM38427.1 - 0.22 9.7 4.0 0.098 10.9 0.4 2.0 2 0 0 2 2 2 0 CDC45-like protein F-box-like PF12937.7 GAM38427.1 - 0.25 11.3 1.5 1.2 9.1 1.5 2.2 1 1 0 1 1 1 0 F-box-like U1snRNP70_N PF12220.8 GAM38427.1 - 1.4 9.6 6.8 5.8 7.6 0.2 3.1 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CTP_transf_like PF01467.26 GAM38428.1 - 7.3e-08 32.7 0.0 4.7e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 GAM38428.1 - 0.037 13.9 0.2 0.07 13.0 0.2 1.4 1 0 0 1 1 1 0 FAD synthetase WD40 PF00400.32 GAM38429.1 - 1.2e-13 51.3 10.3 4.6e-06 27.3 0.3 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Acyl_transf_3 PF01757.22 GAM38430.1 - 2.3e-37 128.8 34.0 2.9e-37 128.5 34.0 1.1 1 0 0 1 1 1 1 Acyltransferase family mRNA_triPase PF02940.15 GAM38431.1 - 5.8e-62 209.3 0.0 1.1e-61 208.4 0.0 1.4 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain Spt5-NGN PF03439.13 GAM38432.1 - 3.4e-24 84.5 0.0 6.4e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 GAM38432.1 - 1.3e-17 64.6 8.9 1.3e-17 64.6 8.9 3.9 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 GAM38432.1 - 1.8e-17 63.7 53.4 9.8e-14 51.7 9.2 4.1 2 2 1 3 3 3 3 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 GAM38432.1 - 2.5e-11 43.1 11.5 0.00015 21.6 0.0 5.0 4 0 0 4 4 4 3 KOW motif DUF3912 PF13051.6 GAM38432.1 - 0.088 13.1 2.7 1.7 9.0 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) SDA1 PF05285.12 GAM38432.1 - 1.3 8.4 29.2 2.5 7.5 29.2 1.4 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 GAM38432.1 - 1.4 8.0 31.1 2.9 6.9 31.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Fungal_trans PF04082.18 GAM38433.1 - 3.1e-12 46.1 0.1 4.7e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 GAM38434.1 - 1.2e-13 50.7 34.6 1.2e-13 50.7 34.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM38434.1 - 3.2e-05 23.0 7.3 3.2e-05 23.0 7.3 2.8 1 1 0 2 2 2 1 Sugar (and other) transporter TRIQK PF15168.6 GAM38434.1 - 0.16 11.9 0.1 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family RPN2_C PF18004.1 GAM38436.1 - 6.6e-56 188.7 9.1 1.2e-55 187.8 9.1 1.5 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain Aldo_ket_red PF00248.21 GAM38436.1 - 8.7e-51 172.8 0.0 6.3e-50 170.0 0.0 2.1 2 0 0 2 2 2 1 Aldo/keto reductase family Acyl-CoA_dh_1 PF00441.24 GAM38436.1 - 4.8e-42 143.7 0.4 4.8e-42 143.7 0.4 2.7 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain PC_rep PF01851.22 GAM38436.1 - 9.8e-36 120.4 18.3 1.4e-09 37.8 0.0 8.5 8 0 0 8 8 8 6 Proteasome/cyclosome repeat Acyl-CoA_dh_M PF02770.19 GAM38436.1 - 1.4e-21 76.4 0.1 3.2e-21 75.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HEAT_2 PF13646.6 GAM38436.1 - 6.8e-21 74.5 0.2 2.4e-14 53.5 0.0 4.5 3 1 2 5 5 5 3 HEAT repeats Acyl-CoA_dh_N PF02771.16 GAM38436.1 - 7e-20 71.8 0.2 4.1e-18 66.1 0.0 2.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 GAM38436.1 - 9.1e-19 67.4 0.1 2.1e-18 66.2 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 GAM38436.1 - 6.8e-11 42.6 0.0 6.8e-11 42.6 0.0 2.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HEAT_EZ PF13513.6 GAM38436.1 - 3.2e-06 27.5 0.1 0.0023 18.4 0.0 4.6 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.22 GAM38436.1 - 5.1e-05 23.2 0.0 7.8 7.1 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 GAM38436.1 - 8.6e-05 22.6 0.5 0.031 14.3 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 GAM38436.1 - 0.23 12.2 3.1 2 9.3 0.0 4.2 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat BST2 PF16716.5 GAM38437.1 - 0.0063 17.1 5.8 0.0063 17.1 5.8 3.0 4 0 0 4 4 4 1 Bone marrow stromal antigen 2 Syntaxin-6_N PF09177.11 GAM38437.1 - 0.11 13.0 3.5 2.6 8.7 0.0 3.6 2 2 1 3 3 3 0 Syntaxin 6, N-terminal CHDCT2 PF08074.11 GAM38437.1 - 0.16 12.1 2.8 0.39 10.9 2.8 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Phage_GP20 PF06810.11 GAM38437.1 - 0.17 11.7 9.9 2.4 7.9 1.0 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 RPW8 PF05659.11 GAM38437.1 - 0.54 9.9 5.3 0.18 11.5 1.5 2.0 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF5595 PF18077.1 GAM38437.1 - 1.3 9.2 9.3 0.42 10.7 1.2 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF5595) Allexi_40kDa PF05549.11 GAM38437.1 - 1.7 8.1 5.1 17 4.8 0.2 2.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein FlaC_arch PF05377.11 GAM38437.1 - 2.8 8.4 7.1 0.52 10.8 0.9 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 GAM38437.1 - 6.2 6.9 7.0 1.5 8.9 1.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) EphA2_TM PF14575.6 GAM38438.1 - 0.11 13.4 0.0 0.2 12.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 GAM38438.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family RCR PF12273.8 GAM38438.1 - 0.15 12.7 8.4 0.35 11.5 8.4 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.10 GAM38439.1 - 3.9e-08 32.6 3.6 7.1e-08 31.7 3.6 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Trp_oprn_chp PF09534.10 GAM38439.1 - 0.03 14.1 9.8 0.39 10.5 10.2 2.4 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Gram_pos_anchor PF00746.21 GAM38439.1 - 0.041 13.8 2.5 0.1 12.6 2.5 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF4366 PF14283.6 GAM38439.1 - 0.045 13.8 0.8 0.13 12.3 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) Mid2 PF04478.12 GAM38439.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF5305 PF17231.2 GAM38439.1 - 0.053 12.9 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Peptidase_S49_N PF08496.10 GAM38439.1 - 0.067 13.3 0.3 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3188 PF11384.8 GAM38439.1 - 0.27 11.0 3.2 0.68 9.7 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) TMEM51 PF15345.6 GAM38439.1 - 0.82 9.5 7.5 3.5 7.4 7.5 2.1 1 1 0 1 1 1 0 Transmembrane protein 51 DUF4355 PF14265.6 GAM38439.1 - 1 9.6 6.6 1.7 8.9 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Ctr PF04145.15 GAM38439.1 - 1.2 9.8 4.1 2.8 8.6 4.1 1.7 1 1 0 1 1 1 0 Ctr copper transporter family EphA2_TM PF14575.6 GAM38439.1 - 2.2 9.2 5.6 1.5 9.8 2.8 2.4 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain PMI_typeI PF01238.21 GAM38440.1 - 7.1e-65 219.6 0.0 6.4e-63 213.2 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 GAM38440.1 - 0.023 14.4 0.0 5.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Cupin domain Abhydrolase_1 PF00561.20 GAM38442.1 - 9.1e-05 22.2 0.0 0.00069 19.3 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM38442.1 - 0.049 14.2 0.0 0.13 12.8 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_35 PF01301.19 GAM38443.1 - 1.4e-87 294.3 1.0 2.4e-87 293.5 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 GAM38443.1 - 7.1e-58 194.1 9.0 4.3e-33 114.3 0.0 3.9 4 1 1 5 5 5 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 GAM38443.1 - 7.4e-55 185.6 1.5 1.2e-54 184.9 1.5 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 GAM38443.1 - 3.2e-25 87.5 0.0 1.1e-24 85.8 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 GAM38443.1 - 7.7e-06 25.5 0.5 1.5e-05 24.6 0.5 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GFO_IDH_MocA PF01408.22 GAM38444.1 - 1.4e-16 61.4 0.0 2.9e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 GAM38444.1 - 0.0012 19.5 0.2 0.002 18.8 0.2 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GAM38444.1 - 0.15 12.7 0.4 0.55 10.9 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.25 GAM38445.1 - 4.8e-61 206.7 0.4 7.4e-61 206.1 0.4 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 GAM38445.1 - 5.2e-32 111.2 0.1 9.9e-32 110.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM38445.1 - 1.8e-16 60.0 0.0 2.1e-15 56.6 0.0 2.4 2 0 0 2 2 2 1 Peptidase dimerisation domain Sugar_tr PF00083.24 GAM38447.1 - 2.4e-57 194.8 28.9 3.4e-56 191.0 28.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM38447.1 - 1.5e-23 83.3 32.1 2.3e-23 82.7 32.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_1 PF00232.18 GAM38448.1 - 5.4e-140 466.8 3.1 7.6e-140 466.3 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hyd_65N_2 PF14498.6 GAM38448.1 - 1.9e-43 149.1 0.0 3.9e-43 148.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain SMP PF04927.12 GAM38449.1 - 0.00034 21.0 2.8 0.00048 20.5 2.8 1.3 1 0 0 1 1 1 1 Seed maturation protein K1377 PF15352.6 GAM38449.1 - 0.41 8.9 1.7 0.45 8.7 1.7 1.0 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy AA_permease_2 PF13520.6 GAM38450.1 - 1.7e-56 191.9 45.9 2.5e-56 191.4 45.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM38450.1 - 3.6e-33 114.9 30.6 3.6e-33 114.9 30.6 2.0 2 0 0 2 2 2 1 Amino acid permease Sec62 PF03839.16 GAM38450.1 - 3.5 7.1 4.3 13 5.2 4.3 2.0 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4418 PF14387.6 GAM38451.1 - 0.011 15.9 2.7 0.021 15.0 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) DUF3810 PF12725.7 GAM38451.1 - 0.75 9.1 3.1 1.3 8.4 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Acetyltransf_1 PF00583.25 GAM38452.1 - 0.00015 21.9 0.0 0.00024 21.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM38452.1 - 0.0019 18.1 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM38452.1 - 0.0064 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SGL PF08450.12 GAM38453.1 - 8.1e-68 228.7 1.0 9.4e-68 228.4 1.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 GAM38453.1 - 0.032 14.4 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 Arylesterase Beta-lactamase PF00144.24 GAM38454.1 - 2.9e-73 247.0 0.1 3.3e-73 246.8 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase Acetyltransf_1 PF00583.25 GAM38455.1 - 2.2e-15 56.9 0.0 2.6e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM38455.1 - 1.7e-11 44.4 0.0 2.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM38455.1 - 1.7e-08 34.4 0.0 2.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM38455.1 - 1.7e-05 24.7 0.0 3.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 GAM38455.1 - 2.7e-05 24.2 0.0 4.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 GAM38455.1 - 0.0002 22.0 0.0 0.00023 21.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 GAM38455.1 - 0.0096 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 GAM38455.1 - 0.13 12.3 0.1 0.31 11.1 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 GAM38455.1 - 0.22 11.2 0.0 0.38 10.4 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ATP-synt_C PF00137.21 GAM38456.1 - 7.7e-09 35.8 12.5 1.4e-08 34.9 12.5 1.5 1 0 0 1 1 1 1 ATP synthase subunit C Glyco_transf_15 PF01793.16 GAM38457.1 - 5.3e-114 380.8 11.9 6.1e-114 380.6 11.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase RabGAP-TBC PF00566.18 GAM38458.1 - 1.7e-29 103.0 0.0 2.5e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PNP_UDP_1 PF01048.20 GAM38459.1 - 2.2e-09 36.9 0.0 2.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily HhH-GPD PF00730.25 GAM38460.1 - 3.2e-07 30.7 0.0 5.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Fungal_trans PF04082.18 GAM38461.1 - 4.4e-21 75.1 0.0 1.2e-20 73.6 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM38461.1 - 5.1e-09 36.1 10.8 1.2e-08 35.0 10.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L37ae PF01780.19 GAM38462.1 - 3.5e-36 123.2 4.6 4.7e-36 122.7 4.6 1.2 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 GAM38462.1 - 0.026 14.7 1.4 0.042 14.0 1.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-FCS PF06467.14 GAM38462.1 - 0.039 13.9 2.3 4.6 7.3 0.2 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif C1_2 PF03107.16 GAM38462.1 - 0.047 14.0 2.3 2.3 8.6 0.2 2.2 1 1 1 2 2 2 0 C1 domain DUF1451 PF07295.11 GAM38462.1 - 0.049 13.7 0.4 0.078 13.0 0.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zn_Tnp_IS1595 PF12760.7 GAM38462.1 - 0.066 13.2 3.5 0.13 12.2 3.5 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Amidohydro_3 PF07969.11 GAM38463.1 - 1.5e-12 47.8 0.1 1.2e-07 31.6 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 GAM38463.1 - 6.2e-10 38.9 0.0 1.9e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family Pkinase PF00069.25 GAM38464.1 - 2e-40 138.9 0.0 3.6e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain E1-E2_ATPase PF00122.20 GAM38464.1 - 7.1e-37 126.7 3.4 7.1e-37 126.7 3.4 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAM38464.1 - 7e-31 107.3 1.2 7e-31 107.3 1.2 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Pkinase_Tyr PF07714.17 GAM38464.1 - 8.7e-22 77.6 0.0 1.7e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Cation_ATPase PF13246.6 GAM38464.1 - 2.4e-18 66.0 0.0 5.1e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM38464.1 - 1.6e-17 64.5 0.0 1.2e-08 35.6 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM38464.1 - 2.8e-12 46.1 0.0 6.4e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus PNP_UDP_1 PF01048.20 GAM38464.1 - 9.1e-06 25.1 0.1 2.5e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Phosphorylase superfamily Kinase-like PF14531.6 GAM38464.1 - 3.3e-05 23.4 0.1 0.0001 21.8 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Hydrolase_3 PF08282.12 GAM38464.1 - 0.0061 16.3 0.3 0.017 14.9 0.3 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Kdo PF06293.14 GAM38464.1 - 0.026 13.9 0.1 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.25 GAM38465.1 - 1.2e-31 109.7 0.1 1.7e-31 109.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM38465.1 - 8.8e-21 74.5 0.2 1.2e-20 74.0 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM38465.1 - 7.5e-07 29.2 0.3 4.8e-05 23.3 0.1 2.1 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 GAM38465.1 - 0.096 12.1 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Asp PF00026.23 GAM38466.1 - 9.3e-62 209.2 5.3 1.2e-61 208.8 5.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM38466.1 - 7.9e-09 36.0 2.6 2.6e-05 24.6 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAM38466.1 - 7.7e-07 29.0 0.0 2.7e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 GAM38466.1 - 0.033 14.8 2.3 42 4.9 0.0 4.3 3 1 1 4 4 4 0 Aspartyl protease DUF508 PF04370.12 GAM38467.1 - 0.065 13.0 0.0 0.79 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF508) FtsK_alpha PF17854.1 GAM38467.1 - 0.12 12.6 2.4 0.86 9.8 0.1 2.3 2 0 0 2 2 2 0 FtsK alpha domain DUF2877 PF11392.8 GAM38467.1 - 0.2 12.4 0.8 0.55 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) HALZ PF02183.18 GAM38467.1 - 0.21 11.8 0.3 0.21 11.8 0.3 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Rootletin PF15035.6 GAM38467.1 - 4.1 7.4 15.4 82 3.1 15.3 2.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SUR7 PF06687.12 GAM38468.1 - 1.5e-51 175.1 11.5 1.8e-51 174.8 11.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 GAM38468.1 - 0.0033 16.9 3.6 0.0065 16.0 3.6 1.5 1 0 0 1 1 1 1 Clc-like DUF373 PF04123.13 GAM38468.1 - 0.06 12.8 3.7 0.084 12.3 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) WD40 PF00400.32 GAM38469.1 - 4.4e-17 62.1 20.1 2.1e-05 25.2 0.3 10.0 10 0 0 10 10 10 4 WD domain, G-beta repeat Nup160 PF11715.8 GAM38469.1 - 0.00073 18.3 0.5 0.0016 17.2 0.1 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 FTR1 PF03239.14 GAM38470.1 - 7.3e-84 281.5 8.5 8.8e-84 281.3 8.5 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3180 PF11377.8 GAM38470.1 - 0.068 13.3 0.4 0.068 13.3 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) Phage_holin_3_6 PF07332.11 GAM38470.1 - 0.47 10.5 8.2 0.15 12.1 0.6 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III ESSS PF10183.9 GAM38470.1 - 1.7 8.9 3.8 13 6.1 0.1 3.3 2 1 1 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Cu-oxidase_2 PF07731.14 GAM38471.1 - 4.3e-46 156.0 7.8 3.2e-40 137.1 0.3 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAM38471.1 - 1.2e-40 138.2 7.4 1.2e-38 131.8 1.3 3.5 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 GAM38471.1 - 4.2e-39 134.2 2.5 1.2e-34 119.8 0.7 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 GAM38471.1 - 0.064 13.4 0.0 17 5.6 0.0 3.4 3 0 0 3 3 3 0 Cupredoxin-like domain Self-incomp_S1 PF05938.11 GAM38471.1 - 0.069 13.7 0.0 9 6.9 0.1 2.4 2 0 0 2 2 2 0 Plant self-incompatibility protein S1 DUF559 PF04480.12 GAM38471.1 - 0.2 11.5 0.0 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF559) XPG_N PF00752.17 GAM38472.1 - 1.4e-34 118.5 0.0 4e-34 117.1 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 GAM38472.1 - 6.1e-26 90.6 0.1 3.2e-24 85.1 0.0 2.7 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 GAM38472.1 - 0.00013 22.5 0.0 0.00042 20.9 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.20 GAM38472.1 - 0.00027 20.7 0.2 0.00027 20.7 0.2 3.6 3 0 0 3 3 3 1 Ubiquitin interaction motif Transposase_20 PF02371.16 GAM38472.1 - 0.015 15.6 0.6 0.035 14.4 0.0 2.0 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family Pil1 PF13805.6 GAM38473.1 - 4.8e-127 423.0 0.1 6.2e-127 422.6 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 bZIP_2 PF07716.15 GAM38474.1 - 7.3e-10 38.8 12.5 7.3e-10 38.8 12.5 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 GAM38474.1 - 5.8 7.1 17.4 6.1 7.0 12.3 2.5 1 1 1 2 2 2 0 bZIP transcription factor DUF1932 PF09130.11 GAM38475.1 - 3.1e-13 49.5 0.7 4.9e-12 45.7 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1932) MC1 PF05854.11 GAM38475.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 Fungal_trans PF04082.18 GAM38476.1 - 1.3e-17 63.7 1.1 2.1e-17 63.0 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM38476.1 - 2.8e-06 27.3 11.2 5.8e-06 26.3 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 GAM38476.1 - 0.012 15.4 0.1 0.034 14.0 0.1 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Fungal_trans PF04082.18 GAM38477.1 - 9.9e-20 70.7 0.1 2.9e-19 69.1 0.1 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM38477.1 - 0.00038 20.5 7.1 0.00083 19.4 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YgbA_NO PF11756.8 GAM38477.1 - 0.068 13.5 1.4 0.16 12.3 1.4 1.6 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter Spc7_N PF15402.6 GAM38478.1 - 0 1153.6 61.3 0 1152.8 61.3 1.4 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 GAM38478.1 - 3.8e-126 420.1 6.2 3.8e-126 420.1 6.2 2.5 3 0 0 3 3 3 1 Spc7 kinetochore protein PI3K_P85_iSH2 PF16454.5 GAM38478.1 - 2.8 7.5 13.3 0.51 9.9 5.0 3.5 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Ribosomal_S17_N PF16205.5 GAM38479.1 - 4.9e-33 113.3 0.4 7.9e-33 112.7 0.4 1.3 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 GAM38479.1 - 1.2e-26 92.6 0.4 2.3e-26 91.7 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 ANTH PF07651.16 GAM38482.1 - 9.1e-48 162.6 3.8 1.5e-38 132.4 0.3 2.5 3 0 0 3 3 3 2 ANTH domain Isochorismatase PF00857.20 GAM38483.1 - 4e-14 53.2 0.6 1.2e-12 48.3 0.1 2.0 1 1 1 2 2 2 2 Isochorismatase family adh_short PF00106.25 GAM38484.1 - 1.4e-28 99.7 0.1 2.2e-28 99.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM38484.1 - 6.1e-24 84.9 0.1 9.7e-24 84.2 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM38484.1 - 1.9e-09 37.7 0.1 4.7e-09 36.4 0.1 1.6 2 0 0 2 2 2 1 KR domain Fungal_trans_2 PF11951.8 GAM38484.1 - 5.4e-07 28.8 0.1 5.4e-07 28.8 0.1 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 GAM38484.1 - 2e-05 24.6 0.0 4.8e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM38484.1 - 0.0064 16.0 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAM38484.1 - 0.0075 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Gpr1_Fun34_YaaH PF01184.19 GAM38485.1 - 1.7e-89 298.9 19.7 2e-89 298.7 19.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Cmc1 PF08583.10 GAM38487.1 - 0.16 12.0 2.5 0.4 10.8 2.5 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Mitoc_L55 PF09776.9 GAM38487.1 - 0.17 11.6 1.5 0.5 10.1 0.5 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 WD40 PF00400.32 GAM38488.1 - 3.8e-18 65.5 14.1 0.00044 21.0 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM38488.1 - 7.2e-15 55.1 0.0 4.2e-05 23.8 0.0 5.1 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM38488.1 - 0.00019 21.3 0.3 0.023 14.6 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.10 GAM38488.1 - 0.0037 17.1 0.2 0.015 15.2 0.2 2.1 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 GAM38488.1 - 0.007 15.4 0.1 7.2 5.5 0.0 3.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAM38488.1 - 0.084 12.8 7.2 10 6.2 0.6 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Oxidored_FMN PF00724.20 GAM38489.1 - 2.8e-97 326.1 0.0 3.5e-97 325.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.21 GAM38489.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme DUF1848 PF08902.11 GAM38489.1 - 0.044 13.5 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Glyco_transf_20 PF00982.21 GAM38490.1 - 2.8e-154 514.3 0.0 4e-154 513.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAM38490.1 - 1.2e-31 109.7 0.0 2.1e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_20 PF00982.21 GAM38491.1 - 1.4e-194 647.2 0.0 1.6e-194 647.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 GAM38491.1 - 0.016 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain Rad4 PF03835.15 GAM38492.1 - 3.4e-14 52.8 3.0 7.6e-14 51.6 3.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 GAM38492.1 - 5.6e-10 39.7 1.8 5.6e-10 39.7 1.8 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily Cellulase PF00150.18 GAM38493.1 - 2.2e-52 178.3 1.9 2.7e-52 177.9 1.9 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-C2H2_4 PF13894.6 GAM38494.1 - 0.11 13.4 0.3 0.11 13.4 0.3 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM38494.1 - 0.16 12.5 8.3 0.88 10.2 0.2 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type PIP5K PF01504.18 GAM38497.1 - 1.1e-34 120.0 0.3 6.7e-26 91.1 0.4 2.6 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 GAM38497.1 - 3.8e-29 101.7 0.0 6.6e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 GAM38497.1 - 2.4e-15 56.4 3.4 2.4e-15 56.4 3.4 1.9 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.22 GAM38497.1 - 0.0063 16.4 2.4 0.02 14.8 2.4 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) ADH_zinc_N PF00107.26 GAM38498.1 - 1.1e-21 77.1 0.0 2.6e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM38498.1 - 3.5e-12 46.2 1.3 3.5e-10 39.7 1.1 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM38498.1 - 0.00012 23.1 0.0 0.00026 22.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aldedh PF00171.22 GAM38499.1 - 2.1e-119 399.1 0.4 6.2e-116 387.6 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 GAM38499.1 - 0.0023 17.1 0.0 0.0037 16.4 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) PK PF00224.21 GAM38500.1 - 4.9e-176 584.7 4.1 6.5e-176 584.3 4.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAM38500.1 - 8.3e-38 129.2 0.0 2.7e-37 127.6 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GAM38500.1 - 5.3e-05 22.5 0.2 0.00015 20.9 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 GAM38500.1 - 0.011 14.7 0.0 0.11 11.5 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain NTP_transf_2 PF01909.23 GAM38500.1 - 0.072 13.4 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF3506 PF12014.8 GAM38501.1 - 2.2e-51 173.5 0.0 5.3e-51 172.3 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 GAM38501.1 - 2.5e-10 40.1 1.1 2.5e-10 40.1 1.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAM38501.1 - 3.4e-08 33.2 0.3 3.4e-08 33.2 0.3 1.8 2 0 0 2 2 2 1 F-box domain Elongin_A PF06881.11 GAM38501.1 - 0.0014 19.1 0.0 0.0039 17.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box_4 PF15966.5 GAM38501.1 - 0.087 12.7 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 F-box Lebercilin PF15619.6 GAM38502.1 - 0.0014 18.3 12.3 0.0014 18.3 12.3 3.8 4 0 0 4 4 4 2 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 GAM38502.1 - 0.0058 17.2 13.4 0.0058 17.2 13.4 4.9 3 1 2 5 5 5 1 Apg6 coiled-coil region DUF948 PF06103.11 GAM38502.1 - 0.031 14.5 13.2 0.53 10.6 1.7 3.7 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Val_tRNA-synt_C PF10458.9 GAM38502.1 - 0.21 11.9 11.8 0.4 11.0 0.6 4.8 4 1 1 5 5 5 0 Valyl tRNA synthetase tRNA binding arm Atg14 PF10186.9 GAM38502.1 - 1.7 7.7 25.0 3.3 6.7 17.4 3.0 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 GAM38502.1 - 6.7 6.7 24.4 0.057 13.4 2.9 3.8 2 1 2 4 4 4 0 Laminin Domain II AAA_27 PF13514.6 GAM38502.1 - 8.6 5.9 11.6 3.4 7.2 8.2 2.2 2 1 0 2 2 2 0 AAA domain DUF1769 PF08588.10 GAM38503.1 - 9.6e-27 93.0 0.8 1.8e-26 92.1 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Tannase PF07519.11 GAM38504.1 - 0.21 10.5 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase MFS_1 PF07690.16 GAM38505.1 - 2.7e-16 59.4 17.4 1.2e-14 54.0 13.5 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 GAM38505.1 - 1.2e-06 27.6 6.7 6.3e-06 25.2 6.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Dscam_C PF12355.8 GAM38505.1 - 0.0097 16.9 0.0 0.0097 16.9 0.0 2.5 3 1 0 3 3 3 1 Down syndrome cell adhesion molecule C terminal Zn_clus PF00172.18 GAM38505.1 - 0.051 13.7 10.1 0.1 12.8 10.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_4 PF06779.14 GAM38505.1 - 0.18 11.0 13.5 0.011 15.1 4.9 2.4 1 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB NAD_binding_10 PF13460.6 GAM38506.1 - 3.2e-16 59.8 0.0 4e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM38506.1 - 0.00014 21.5 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 GAM38506.1 - 0.00028 21.3 0.0 0.00058 20.3 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAM38506.1 - 0.00037 20.7 0.0 0.00056 20.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 GAM38506.1 - 0.015 16.0 0.2 0.3 11.8 0.1 2.4 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Glyco_hydro_15 PF00723.21 GAM38507.1 - 2.1e-50 171.8 0.0 5.3e-46 157.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 15 Iso_dh PF00180.20 GAM38508.1 - 6.5e-99 331.4 0.0 1e-98 330.8 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Peptidase_S58 PF03576.14 GAM38509.1 - 7.1e-97 324.5 1.3 8.1e-97 324.3 1.3 1.0 1 0 0 1 1 1 1 Peptidase family S58 Vac_Fusion PF02346.16 GAM38512.1 - 0.21 11.2 2.8 0.88 9.2 0.2 3.0 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 YlbD_coat PF14071.6 GAM38513.1 - 0.012 15.9 0.5 0.012 15.9 0.5 2.4 3 1 0 3 3 3 0 Putative coat protein HMG_box_5 PF14887.6 GAM38513.1 - 0.26 11.3 2.5 0.96 9.5 0.3 2.6 3 0 0 3 3 3 0 HMG (high mobility group) box 5 PIN_8 PF18476.1 GAM38515.1 - 0.021 14.7 0.3 0.033 14.1 0.3 1.2 1 0 0 1 1 1 0 PIN like domain Fungal_trans PF04082.18 GAM38516.1 - 0.01 14.9 0.2 0.016 14.3 0.2 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 GAM38517.1 - 1.2e-08 35.1 0.2 1.6e-08 34.7 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM38517.1 - 9.9e-08 31.7 0.0 3.2e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.10 GAM38517.1 - 3.8e-06 26.5 0.0 7e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 HIM1 NmrA PF05368.13 GAM38517.1 - 5.7e-06 26.1 0.8 1.2e-05 25.1 0.4 1.7 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 GAM38517.1 - 0.094 13.2 0.2 0.3 11.5 0.2 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain UVR PF02151.19 GAM38517.1 - 0.13 12.0 0.5 0.34 10.7 0.1 1.9 2 0 0 2 2 2 0 UvrB/uvrC motif YqaH PF17448.2 GAM38517.1 - 0.17 12.2 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized YqaH-like DUF3425 PF11905.8 GAM38518.1 - 1e-31 109.5 0.0 1.6e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) MFS_1 PF07690.16 GAM38519.1 - 6.6e-28 97.6 67.1 2.6e-20 72.7 39.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S8 PF00410.19 GAM38520.1 - 3.3e-11 43.2 0.0 4e-10 39.7 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein S8 FAD_binding_3 PF01494.19 GAM38522.1 - 9e-19 67.9 0.0 6.4e-18 65.1 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM38522.1 - 4.3e-05 22.9 0.0 7.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM38522.1 - 0.00067 19.3 0.1 0.0052 16.4 0.1 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM38522.1 - 0.0018 18.8 0.0 0.019 15.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM38522.1 - 0.0021 18.2 0.1 0.0055 16.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAM38522.1 - 0.0033 16.2 0.1 0.0049 15.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 GAM38522.1 - 0.0049 16.0 0.1 0.01 14.9 0.1 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAM38522.1 - 0.0053 16.1 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 GAM38522.1 - 0.02 14.3 0.6 0.11 11.9 0.3 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 GAM38522.1 - 0.087 11.7 0.0 0.82 8.4 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase SE PF08491.10 GAM38522.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Peptidase_M24 PF00557.24 GAM38523.1 - 7.9e-48 162.9 0.0 9.7e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 GAM38523.1 - 8.3e-20 70.8 6.6 2e-19 69.6 6.6 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 GAM38523.1 - 0.00026 21.0 3.7 0.00026 21.0 3.7 2.2 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 GAM38523.1 - 0.21 11.5 2.7 0.52 10.2 2.7 1.7 1 0 0 1 1 1 0 HIT zinc finger MFS_1 PF07690.16 GAM38524.1 - 1.9e-43 148.7 58.9 6.9e-43 146.9 53.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM38524.1 - 4.3e-13 48.9 10.8 4.3e-13 48.9 10.8 3.2 3 1 1 4 4 4 2 Sugar (and other) transporter EF-hand_1 PF00036.32 GAM38525.1 - 1.9e-12 45.8 9.3 1.7e-05 24.0 0.8 3.7 3 0 0 3 3 3 2 EF hand ZZ PF00569.17 GAM38525.1 - 3.5e-11 42.7 6.4 5.8e-11 42.0 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.6 GAM38525.1 - 1.4e-10 41.5 0.2 1.7e-05 25.2 0.2 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 GAM38525.1 - 2.6e-10 39.4 6.6 9.4e-06 25.2 0.4 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 GAM38525.1 - 0.0003 20.1 8.3 0.15 11.6 0.6 3.3 3 0 0 3 3 3 2 EF hand C1_2 PF03107.16 GAM38525.1 - 0.0014 18.9 4.5 0.0027 18.0 4.5 1.4 1 0 0 1 1 1 1 C1 domain EF-hand_8 PF13833.6 GAM38525.1 - 0.0018 18.1 5.6 0.49 10.3 0.4 3.4 3 0 0 3 3 3 2 EF-hand domain pair DUF966 PF06136.13 GAM38525.1 - 2.5 7.8 7.4 5 6.8 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) B277 PF17623.2 GAM38526.1 - 0.23 10.5 2.8 0.62 9.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF1688 PF07958.11 GAM38527.1 - 2.9e-160 533.6 0.0 3.3e-160 533.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Epimerase PF01370.21 GAM38528.1 - 5.1e-08 32.7 0.0 5.4e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM38528.1 - 0.00034 20.6 0.0 0.0007 19.5 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 GAM38528.1 - 0.0027 16.9 0.0 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 GAM38528.1 - 0.0037 16.9 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 GAM38528.1 - 0.044 14.2 0.0 0.091 13.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAM38528.1 - 0.17 10.9 0.0 0.25 10.3 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family WD40 PF00400.32 GAM38529.1 - 2.1e-26 91.6 8.5 6.4e-07 30.0 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM38529.1 - 1e-14 54.6 0.0 0.00012 22.3 0.0 4.7 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Patatin PF01734.22 GAM38529.1 - 3.7e-05 24.0 0.5 0.0066 16.7 0.0 2.8 3 0 0 3 3 3 2 Patatin-like phospholipase Cornichon PF03311.14 GAM38530.1 - 1.9e-48 163.8 12.4 2.2e-48 163.6 12.4 1.0 1 0 0 1 1 1 1 Cornichon protein ABC2_membrane PF01061.24 GAM38531.1 - 1.1e-38 132.8 19.6 2e-38 132.0 19.6 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAM38531.1 - 2.4e-26 92.9 1.2 2.9e-26 92.6 0.1 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 GAM38531.1 - 2.9e-05 24.1 0.4 0.16 11.8 0.1 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 GAM38531.1 - 0.00034 19.8 23.1 0.00034 19.8 23.1 2.0 1 1 1 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GAM38531.1 - 0.0013 18.7 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 GAM38531.1 - 0.0021 17.7 0.1 0.0048 16.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM38531.1 - 0.0085 16.5 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 GAM38531.1 - 0.03 14.9 0.0 0.099 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAM38531.1 - 0.047 13.3 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 GAM38531.1 - 0.061 12.7 0.0 0.46 9.9 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain SKI PF01202.22 GAM38531.1 - 1.1 9.3 3.1 10 6.2 0.1 2.3 2 0 0 2 2 2 0 Shikimate kinase Laminin_EGF PF00053.24 GAM38531.1 - 1.3 9.2 29.5 0.31 11.2 8.7 3.4 2 1 1 3 3 3 0 Laminin EGF domain DUF87 PF01935.17 GAM38531.1 - 2.2 8.3 3.6 4.8 7.2 0.2 2.4 2 1 0 2 2 2 0 Helicase HerA, central domain Cupin_2 PF07883.11 GAM38532.1 - 3e-13 49.3 0.1 3.8e-09 36.1 0.2 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 GAM38532.1 - 0.00039 20.3 0.2 0.031 14.2 0.2 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.12 GAM38532.1 - 0.031 13.9 0.0 5.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_4 PF08007.12 GAM38532.1 - 0.065 12.7 0.7 0.21 11.0 0.1 1.9 2 0 0 2 2 2 0 Cupin superfamily protein Aminotran_1_2 PF00155.21 GAM38533.1 - 1.5e-26 93.4 0.0 2.5e-26 92.7 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GAM38533.1 - 0.0023 17.0 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V zf-C3HC PF07967.13 GAM38533.1 - 0.011 15.7 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 C3HC zinc finger-like Cys_Met_Meta_PP PF01053.20 GAM38533.1 - 0.012 14.2 0.0 0.018 13.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 GAM38533.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Alliinase_C PF04864.13 GAM38533.1 - 0.032 13.1 0.1 0.058 12.3 0.1 1.4 1 1 0 1 1 1 0 Allinase AMP-binding PF00501.28 GAM38534.1 - 1.5e-64 218.2 0.0 2.2e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM38534.1 - 3.2e-10 40.8 0.0 3.2e-10 40.8 0.0 2.7 3 1 1 4 4 4 1 AMP-binding enzyme C-terminal domain FAD_binding_4 PF01565.23 GAM38535.1 - 5.1e-22 78.1 1.5 1.6e-21 76.5 1.5 1.9 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM38535.1 - 2.5e-10 40.3 2.7 5.9e-10 39.1 2.7 1.7 1 0 0 1 1 1 1 Berberine and berberine like Albumin_I PF08027.11 GAM38535.1 - 3.6 7.3 6.5 1.6 8.4 2.1 2.5 2 0 0 2 2 2 0 Albumin I chain b Ank PF00023.30 GAM38537.1 - 1.8e-33 113.5 4.3 3.9e-06 27.0 0.1 7.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_2 PF12796.7 GAM38537.1 - 2.5e-33 114.5 0.0 4.6e-11 43.1 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM38537.1 - 2.9e-29 101.1 0.1 3.3e-08 33.9 0.0 6.6 5 3 2 7 7 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM38537.1 - 2.1e-26 91.7 0.8 4.7e-06 26.8 0.0 5.8 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM38537.1 - 4.1e-26 88.2 0.4 0.0023 18.3 0.0 7.8 8 0 0 8 8 7 5 Ankyrin repeat Ses_B PF17046.5 GAM38537.1 - 3e-08 33.5 0.1 6.3e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein NACHT PF05729.12 GAM38537.1 - 1.7e-05 24.8 0.1 0.064 13.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 GAM38537.1 - 0.00078 19.9 0.0 0.0023 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 GAM38537.1 - 0.051 12.8 0.0 0.82 8.8 0.0 2.2 1 1 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.22 GAM38537.1 - 0.052 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 GAM38537.1 - 0.057 13.7 0.0 0.2 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAM38537.1 - 0.059 13.5 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAM38537.1 - 0.091 13.3 0.2 0.44 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAM38537.1 - 0.14 12.7 0.0 0.95 10.0 0.0 2.4 3 0 0 3 3 2 0 ABC transporter HeLo PF14479.6 GAM38538.1 - 3.6e-26 92.3 1.5 3.6e-26 92.3 1.5 2.0 1 1 1 2 2 2 1 Prion-inhibition and propagation Goodbye PF17109.5 GAM38538.1 - 3.8e-15 56.4 0.2 3.8e-15 56.4 0.2 3.9 4 1 0 4 4 4 1 fungal STAND N-terminal Goodbye domain Ses_B PF17046.5 GAM38538.1 - 1.4e-07 31.3 21.8 1.7e-07 31.1 4.1 3.4 3 0 0 3 3 3 2 SesB domain on fungal death-pathway protein PGAP1 PF07819.13 GAM38538.1 - 0.0032 17.2 0.0 0.015 15.0 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein PhoU_div PF01865.16 GAM38538.1 - 0.079 12.3 7.8 0.3 10.4 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function DUF47 Abhydrolase_6 PF12697.7 GAM38538.1 - 0.11 13.1 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family SKA2 PF16740.5 GAM38538.1 - 0.16 11.7 10.8 10 5.9 1.3 4.4 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 2 GIT1_C PF12205.8 GAM38538.1 - 1.4 9.0 8.0 0.95 9.6 0.2 3.9 3 1 1 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term MutS_III PF05192.18 GAM38538.1 - 5.9 7.1 10.0 0.94 9.7 2.1 2.8 2 1 0 2 2 2 0 MutS domain III ERM PF00769.19 GAM38539.1 - 0.6 9.9 54.1 0.85 9.4 54.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CAS_C PF12026.8 GAM38540.1 - 0.66 10.0 9.5 0.55 10.3 5.3 2.2 2 0 0 2 2 2 0 Crk-Associated Substrate C-terminal domain Spc7 PF08317.11 GAM38540.1 - 1.4 7.8 21.8 2.1 7.2 21.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 GAM38540.1 - 1.7 9.3 15.8 3.6 8.3 0.3 2.7 1 1 1 2 2 2 0 Initiation control protein YabA FtsJ PF01728.19 GAM38541.1 - 5.3e-13 49.4 0.0 1.1e-12 48.5 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Abhydrolase_3 PF07859.13 GAM38542.1 - 7.8e-10 39.0 0.1 2.3e-09 37.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAM38542.1 - 0.0002 20.4 0.0 0.0016 17.4 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 GAM38542.1 - 0.00021 20.9 0.0 0.0049 16.4 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 GAM38542.1 - 0.00051 19.0 1.0 0.00086 18.3 1.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 GAM38542.1 - 0.059 12.6 0.0 0.093 12.0 0.0 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Glyco_hydro_79C PF16862.5 GAM38543.1 - 7.4e-23 81.4 1.4 9.2e-23 81.1 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain He_PIG PF05345.12 GAM38543.1 - 0.0045 17.1 1.6 0.0045 17.1 1.6 1.9 2 0 0 2 2 2 1 Putative Ig domain Ketoacyl-synt_2 PF13723.6 GAM38543.1 - 0.21 11.2 0.7 0.32 10.6 0.4 1.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Glyco_trans_2_3 PF13632.6 GAM38544.1 - 5.7e-24 85.1 2.3 7.4e-24 84.8 2.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAM38544.1 - 8.9e-11 42.1 0.4 1e-10 41.9 0.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAM38544.1 - 0.13 12.1 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAM38544.1 - 0.16 11.4 0.3 6.9 6.1 0.3 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 21 MFS_1 PF07690.16 GAM38545.1 - 2.2e-26 92.6 25.5 3.5e-26 92.0 25.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM38545.1 - 1.7e-09 36.7 9.0 2e-09 36.4 9.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM38545.1 - 0.86 8.4 19.6 0.022 13.6 11.5 2.2 2 1 0 2 2 2 0 Sugar (and other) transporter Carn_acyltransf PF00755.20 GAM38546.1 - 4.9e-96 322.6 0.0 6.8e-61 206.6 0.1 2.2 1 1 1 2 2 2 2 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 GAM38546.1 - 9.9e-77 257.9 0.0 1.9e-76 257.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 GAM38546.1 - 9.2e-54 182.7 0.0 1.5e-53 182.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 GAM38546.1 - 7.8e-51 172.5 0.7 2e-50 171.2 0.3 2.0 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 GAM38546.1 - 1.4e-41 143.0 0.1 2.9e-41 142.0 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM38546.1 - 7.1e-37 126.0 0.1 7e-36 122.8 0.1 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 GAM38546.1 - 3.3e-14 52.8 0.2 1.7e-13 50.5 0.0 2.4 3 0 0 3 3 3 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 GAM38546.1 - 2.2e-13 50.7 0.0 6.1e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 GAM38546.1 - 2.3e-11 43.8 1.0 3e-09 37.0 0.1 4.0 4 0 0 4 4 4 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM38546.1 - 5.6e-10 40.4 0.0 6.1e-09 37.0 0.0 2.8 3 0 0 3 3 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 GAM38546.1 - 4.2e-07 29.8 0.1 9.5e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_12 PF08242.12 GAM38546.1 - 6.6e-07 30.0 0.0 2.6e-06 28.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 GAM38546.1 - 8.3e-07 29.3 0.3 1.9e-06 28.1 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 GAM38546.1 - 0.00012 21.6 0.0 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 GAM38546.1 - 0.00013 21.8 0.0 0.00037 20.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 GAM38546.1 - 0.00042 19.6 0.0 0.00088 18.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 GAM38546.1 - 0.00077 20.1 0.0 0.012 16.3 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 GAM38546.1 - 0.00081 18.8 0.1 0.0019 17.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.12 GAM38546.1 - 0.0028 18.3 0.0 0.016 15.9 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain PALP PF00291.25 GAM38546.1 - 0.0041 16.6 0.9 0.13 11.7 0.0 2.8 3 0 0 3 3 3 1 Pyridoxal-phosphate dependent enzyme GDP_Man_Dehyd PF16363.5 GAM38546.1 - 0.0047 16.4 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Methyltransf_24 PF13578.6 GAM38546.1 - 0.009 17.0 0.0 0.54 11.3 0.0 3.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM38546.1 - 0.01 15.7 0.0 0.058 13.2 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain 3Beta_HSD PF01073.19 GAM38546.1 - 0.05 12.6 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 GAM38546.1 - 0.06 13.9 0.0 0.3 11.7 0.0 2.2 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3435 PF11917.8 GAM38547.1 - 5.6e-26 91.4 4.2 3.1e-22 79.1 2.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) Ank_2 PF12796.7 GAM38548.1 - 2.4e-21 76.1 0.0 1.9e-09 38.0 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM38548.1 - 2.1e-15 55.2 0.1 0.0017 18.7 0.0 6.8 6 1 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 GAM38548.1 - 3.9e-14 52.8 0.1 0.0048 17.5 0.0 5.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM38548.1 - 4.2e-13 49.1 0.0 0.00038 20.8 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 GAM38548.1 - 1.6e-08 34.6 0.1 0.0015 18.8 0.0 4.3 3 2 1 4 4 4 2 Ankyrin repeats (many copies) HeLo PF14479.6 GAM38548.1 - 0.02 14.8 0.2 0.03 14.2 0.2 1.2 1 0 0 1 1 1 0 Prion-inhibition and propagation TAP42 PF04177.12 GAM38548.1 - 0.1 11.7 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 TAP42-like family Fungal_trans PF04082.18 GAM38549.1 - 3.7e-10 39.3 0.1 6.5e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM38549.1 - 1.8e-07 31.2 8.5 3.1e-07 30.4 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HlyIII PF03006.20 GAM38550.1 - 3e-60 203.7 19.1 3.8e-60 203.4 19.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related FmiP_Thoc5 PF09766.9 GAM38551.1 - 1.3e-32 113.5 12.7 1.6e-32 113.2 12.7 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 GAM38551.1 - 0.0058 16.7 3.3 0.0058 16.7 3.3 2.2 2 0 0 2 2 2 1 Spermatogenesis-associated C-terminus DUF4200 PF13863.6 GAM38551.1 - 0.015 15.7 11.4 0.14 12.5 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Mod_r PF07200.13 GAM38551.1 - 0.032 14.3 10.9 0.72 9.9 4.6 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Casc1_N PF15927.5 GAM38551.1 - 0.054 13.2 13.2 0.026 14.2 8.8 2.0 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus YabA PF06156.13 GAM38551.1 - 0.88 10.2 6.2 8.7 7.0 1.5 2.3 2 0 0 2 2 2 0 Initiation control protein YabA DUF87 PF01935.17 GAM38551.1 - 0.89 9.6 4.4 1.6 8.8 4.4 1.3 1 1 0 1 1 1 0 Helicase HerA, central domain Flagellin_N PF00669.20 GAM38551.1 - 1.3 9.1 6.6 0.31 11.2 0.4 2.4 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region DUF349 PF03993.12 GAM38551.1 - 1.8 8.9 10.7 0.5 10.7 6.6 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) PIG-S PF10510.9 GAM38552.1 - 2.5e-179 597.4 7.2 2.8e-179 597.2 7.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Granulin PF00396.18 GAM38553.1 - 0.62 10.4 7.6 1.3 9.4 7.6 1.5 1 0 0 1 1 1 0 Granulin SprA-related PF12118.8 GAM38553.1 - 5.8 5.9 13.7 9.3 5.3 13.7 1.4 1 0 0 1 1 1 0 SprA-related family DUF3295 PF11702.8 GAM38553.1 - 6.8 5.9 13.6 5.1 6.3 12.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3295) Sod_Fe_C PF02777.18 GAM38554.1 - 4.7e-17 62.0 0.0 4.5e-08 33.2 0.0 2.7 3 0 0 3 3 3 2 Iron/manganese superoxide dismutases, C-terminal domain Polyketide_cyc PF03364.20 GAM38555.1 - 3.5e-21 75.8 0.0 8.3e-21 74.5 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 GAM38555.1 - 0.012 15.9 0.1 0.029 14.7 0.1 1.6 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport IF2_N PF04760.15 GAM38556.1 - 0.035 13.9 0.2 0.4 10.5 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Phosphoesterase PF04185.14 GAM38557.1 - 5.8e-22 78.4 3.6 5.8e-22 78.4 3.6 2.1 1 1 1 2 2 2 1 Phosphoesterase family Activator_LAG-3 PF11498.8 GAM38557.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 YopD PF05844.12 GAM38557.1 - 0.27 10.2 0.1 0.5 9.3 0.1 1.3 1 0 0 1 1 1 0 YopD protein Fungal_trans_2 PF11951.8 GAM38558.1 - 5.2e-08 32.1 0.0 1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM38558.1 - 2.5e-05 24.3 3.6 7.2e-05 22.8 3.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DinB_2 PF12867.7 GAM38558.1 - 0.082 13.4 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 DinB superfamily UbiA PF01040.18 GAM38559.1 - 3.5e-15 56.0 4.4 4.5e-15 55.6 4.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family AmiS_UreI PF02293.15 GAM38559.1 - 0.15 12.1 7.8 2.6 8.0 4.3 2.4 2 1 0 2 2 2 0 AmiS/UreI family transporter zf-CCHC PF00098.23 GAM38560.1 - 2.3e-07 30.6 15.2 4.6e-05 23.3 2.9 4.6 4 1 1 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.6 GAM38560.1 - 4.8e-05 23.1 31.4 0.01 15.6 6.2 4.4 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 GAM38560.1 - 0.0064 16.2 0.5 0.0064 16.2 0.5 4.1 1 1 3 4 4 4 3 Zinc knuckle zf-CCHC_5 PF14787.6 GAM38560.1 - 0.0074 16.0 4.3 0.0074 16.0 4.3 4.2 2 1 3 5 5 5 1 GAG-polyprotein viral zinc-finger Copper-fist PF00649.18 GAM38560.1 - 0.065 12.7 1.4 0.065 12.7 1.4 3.4 1 1 2 3 3 3 0 Copper fist DNA binding domain Methyltransf_12 PF08242.12 GAM38561.1 - 1.1e-14 55.0 0.1 3e-14 53.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM38561.1 - 3.3e-14 53.4 0.0 1.7e-13 51.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM38561.1 - 8.2e-14 51.8 0.8 1.1e-13 51.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM38561.1 - 2.2e-12 47.5 0.0 1.1e-11 45.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM38561.1 - 2.3e-10 40.5 0.0 4.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM38561.1 - 1.6e-06 27.7 0.0 3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 GAM38561.1 - 5.4e-05 23.1 0.1 0.0062 16.4 0.1 2.4 1 1 0 1 1 1 1 Hypothetical methyltransferase DUF3419 PF11899.8 GAM38561.1 - 0.00088 18.5 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.6 GAM38561.1 - 0.00091 20.2 0.0 0.0031 18.5 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 GAM38561.1 - 0.0018 17.5 0.0 0.24 10.6 0.0 2.4 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_32 PF13679.6 GAM38561.1 - 0.0018 18.2 0.1 0.047 13.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAM38561.1 - 0.0098 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF3408 PF11888.8 GAM38561.1 - 1.6 8.9 8.4 0.42 10.8 4.6 2.0 3 0 0 3 3 2 0 Protein of unknown function (DUF3408) MSA-2c PF12238.8 GAM38562.1 - 0.031 14.3 0.6 0.089 12.8 0.6 1.7 1 1 0 1 1 1 0 Merozoite surface antigen 2c Ank_2 PF12796.7 GAM38563.1 - 2.1e-53 178.8 0.6 1.4e-13 51.2 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM38563.1 - 1.9e-44 149.5 11.4 2.1e-10 40.9 0.1 6.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM38563.1 - 4.7e-33 109.5 3.2 0.0023 18.3 0.1 8.5 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 GAM38563.1 - 6.4e-32 109.2 14.3 1.2e-08 35.0 0.0 7.9 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 GAM38563.1 - 7.3e-31 105.3 9.1 6.6e-05 23.2 0.0 8.9 9 0 0 9 9 9 7 Ankyrin repeat Peptidase_M3 PF01432.20 GAM38564.1 - 1.8e-98 330.8 0.0 1e-97 328.3 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M3 DUF3328 PF11807.8 GAM38565.1 - 2.9e-28 99.1 0.2 3.2e-28 99.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RVT_1 PF00078.27 GAM38565.1 - 0.073 12.6 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) WBP-1 PF11669.8 GAM38566.1 - 0.28 11.8 8.7 1.8 9.2 0.6 2.8 3 0 0 3 3 3 0 WW domain-binding protein 1 UbiA PF01040.18 GAM38567.1 - 1e-54 185.5 23.0 1.5e-54 185.0 23.0 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family PQ-loop PF04193.14 GAM38568.1 - 7.7e-21 73.6 4.9 1.2e-10 41.0 0.8 2.5 2 0 0 2 2 2 2 PQ loop repeat ASFV_J13L PF05568.11 GAM38568.1 - 0.0058 16.4 0.7 0.036 13.8 0.0 2.1 2 0 0 2 2 2 1 African swine fever virus J13L protein Med8 PF10232.9 GAM38569.1 - 1.1e-46 159.3 0.0 1.4e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF2457 PF10446.9 GAM38569.1 - 0.37 9.9 7.3 0.45 9.6 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TT_ORF2 PF02957.15 GAM38569.1 - 0.58 11.1 0.0 0.58 11.1 0.0 2.2 1 1 1 2 2 2 0 TT viral ORF2 RNA_pol_3_Rpc31 PF11705.8 GAM38569.1 - 0.61 10.3 8.5 0.89 9.8 8.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 GAM38569.1 - 0.74 9.5 5.4 1.1 8.9 5.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GAM38569.1 - 1.9 7.8 9.7 2.5 7.3 9.7 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 GAM38569.1 - 2.6 6.1 4.3 3.3 5.8 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 GAM38569.1 - 7 7.1 13.1 13 6.3 13.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Abhydrolase_6 PF12697.7 GAM38570.1 - 0.00026 21.7 0.0 0.00048 20.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM38570.1 - 0.0019 17.9 0.3 0.56 9.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF3336 PF11815.8 GAM38571.1 - 4.3e-35 120.4 0.6 8.8e-35 119.4 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAM38571.1 - 2.2e-19 70.5 0.0 5.9e-19 69.1 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase Abhydrolase_6 PF12697.7 GAM38572.1 - 1e-13 52.4 0.1 2.8e-13 51.0 0.0 1.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM38572.1 - 1.2e-11 44.8 0.0 2.3e-11 43.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM38572.1 - 2.9e-06 26.7 0.0 7.5e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EthD PF07110.11 GAM38572.1 - 2.8e-05 25.2 0.3 0.15 13.2 0.0 2.9 2 0 0 2 2 2 2 EthD domain Esterase PF00756.20 GAM38572.1 - 6.8e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 GAM38572.1 - 0.00022 20.0 0.0 0.0024 16.6 0.0 2.2 1 1 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.16 GAM38572.1 - 0.22 11.3 0.0 0.4 10.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Ost5 PF05251.12 GAM38573.1 - 1.4 9.3 10.7 0.079 13.2 2.1 2.8 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 DUF485 PF04341.12 GAM38573.1 - 9.4 6.3 10.4 3.5 7.7 4.6 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF485 NAD_binding_10 PF13460.6 GAM38574.1 - 2.5e-06 27.5 0.0 2.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAM38574.1 - 0.0001 21.4 0.0 0.00025 20.1 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 GAM38574.1 - 0.00036 20.6 0.0 0.00051 20.2 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 GAM38574.1 - 0.0006 19.3 0.0 0.0022 17.5 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAM38574.1 - 0.0064 15.7 0.0 0.058 12.5 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 GAM38574.1 - 0.007 16.8 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Carb_anhydrase PF00194.21 GAM38576.1 - 0.23 10.9 0.1 0.32 10.5 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase Alpha-amylase PF00128.24 GAM38577.1 - 6.9e-44 150.8 0.1 1e-43 150.2 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 GAM38577.1 - 2.6e-24 85.3 0.0 6e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.6 GAM38577.1 - 0.044 12.9 0.2 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain UbiA PF01040.18 GAM38578.1 - 1.5e-26 93.2 12.6 2e-26 92.8 12.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2157 PF09925.9 GAM38578.1 - 4.4 7.1 8.0 0.41 10.4 1.4 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) Fungal_trans PF04082.18 GAM38579.1 - 5.9e-18 64.8 0.0 1.7e-17 63.3 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain AA_permease PF00324.21 GAM38580.1 - 4.9e-118 394.7 45.5 6.1e-118 394.4 45.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM38580.1 - 7.5e-38 130.5 50.1 7.5e-38 130.5 49.0 1.4 1 1 1 2 2 2 2 Amino acid permease Aldo_ket_red PF00248.21 GAM38581.1 - 2.3e-47 161.6 0.0 2.8e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EF-hand_14 PF17959.1 GAM38582.1 - 0.084 13.2 0.2 0.16 12.4 0.2 1.5 1 0 0 1 1 1 0 EF-hand domain FlaC_arch PF05377.11 GAM38584.1 - 0.0006 20.2 0.4 0.11 12.9 0.0 3.1 2 1 0 2 2 2 1 Flagella accessory protein C (FlaC) FAP206 PF12018.8 GAM38584.1 - 0.012 15.2 0.9 0.015 14.8 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function TBCA PF02970.16 GAM38584.1 - 0.056 13.8 3.4 0.08 13.3 1.0 2.0 1 1 1 2 2 2 0 Tubulin binding cofactor A DUF4404 PF14357.6 GAM38584.1 - 0.087 13.5 5.0 0.31 11.7 3.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) SNF2_N PF00176.23 GAM38585.1 - 5.2e-18 64.9 0.5 7.8e-12 44.6 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM38585.1 - 9.8e-13 48.4 0.0 2.1e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM38585.1 - 0.0077 16.2 0.0 4.7 7.2 0.0 2.4 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit BTB PF00651.31 GAM38586.1 - 0.00074 19.7 0.0 0.01 16.1 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain AAA_16 PF13191.6 GAM38587.1 - 0.0018 18.7 0.1 0.0085 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 GAM38587.1 - 0.004 17.6 0.0 0.17 12.3 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM38587.1 - 0.12 12.7 0.0 0.46 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain BTB PF00651.31 GAM38588.1 - 5.1e-15 55.7 4.8 1.6e-05 25.0 0.0 4.5 5 0 0 5 5 5 3 BTB/POZ domain DUF4820 PF16091.5 GAM38588.1 - 0.016 14.6 4.8 0.25 10.7 0.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4820) PSD5 PF07637.11 GAM38588.1 - 0.04 14.3 0.3 2.6 8.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) Ribosomal_60s PF00428.19 GAM38588.1 - 2.5 8.8 8.8 5.5 7.6 3.3 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3716 PF12511.8 GAM38589.1 - 4.7e-14 52.2 5.2 4.7e-14 52.2 5.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3716) TFIIF_alpha PF05793.12 GAM38589.1 - 0.021 13.5 23.0 0.027 13.1 23.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 GAM38589.1 - 0.76 7.9 21.8 1.1 7.4 21.8 1.2 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 GAM38589.1 - 1.3 7.8 4.8 1.4 7.6 4.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 GAM38589.1 - 3 7.1 27.2 4.1 6.6 27.2 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GAM38589.1 - 3.6 6.9 26.3 4.9 6.5 26.3 1.1 1 0 0 1 1 1 0 SDA1 Drc1-Sld2 PF11719.8 GAM38589.1 - 8.9 5.7 14.9 12 5.3 14.9 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein NmrA PF05368.13 GAM38591.1 - 1.9e-60 204.3 0.3 2.2e-60 204.1 0.3 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM38591.1 - 4.4e-15 56.0 0.0 6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM38591.1 - 0.00014 21.4 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAM38591.1 - 0.0004 20.6 0.3 0.00094 19.4 0.3 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 GAM38591.1 - 0.00059 18.9 0.0 0.00081 18.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 GAM38591.1 - 0.0082 16.4 0.4 0.014 15.7 0.4 1.3 1 0 0 1 1 1 1 TrkA-N domain DUF4246 PF14033.6 GAM38593.1 - 3.5e-111 372.5 0.4 7.3e-62 209.9 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) BTB PF00651.31 GAM38593.1 - 0.0023 18.1 0.2 0.0063 16.7 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain ToxS PF17323.2 GAM38593.1 - 0.028 14.1 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Trans-membrane regulatory protein ToxS BTB PF00651.31 GAM38594.1 - 1.2e-07 32.0 0.6 1.6e-06 28.3 0.1 2.4 3 0 0 3 3 3 1 BTB/POZ domain BTB PF00651.31 GAM38595.1 - 1.8e-05 24.9 0.4 0.0045 17.2 0.0 2.8 2 1 0 2 2 2 2 BTB/POZ domain Metallophos PF00149.28 GAM38596.1 - 7.2e-16 59.3 0.6 1.2e-15 58.6 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.32 GAM38596.1 - 0.00046 20.9 11.0 6.1 7.9 0.4 6.4 5 2 1 6 6 6 3 WD domain, G-beta repeat SLATT_fungal PF18142.1 GAM38597.1 - 4.3e-30 104.2 0.0 5.8e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Zn_clus PF00172.18 GAM38598.1 - 6e-10 39.1 6.5 9.9e-10 38.4 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM38598.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain S1-like PF14444.6 GAM38598.1 - 0.039 13.9 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 S1-like MFS_1 PF07690.16 GAM38599.1 - 1.6e-26 93.1 39.2 1.6e-26 93.1 39.2 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.13 GAM38600.1 - 6.5e-30 104.4 0.0 1.1e-29 103.7 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM38600.1 - 1.5e-10 41.3 0.0 2.2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Zn_clus PF00172.18 GAM38601.1 - 3.4e-07 30.3 7.8 3.4e-07 30.3 7.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Helo_like_N PF17111.5 GAM38602.1 - 2.3e-34 118.6 5.9 8.4e-27 93.9 0.6 3.1 2 1 0 2 2 2 2 Fungal N-terminal domain of STAND proteins DUF2278 PF10042.9 GAM38604.1 - 3e-71 239.7 0.0 6e-71 238.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) SIR2_2 PF13289.6 GAM38604.1 - 9.8e-16 58.2 0.0 1.9e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 SIR2-like domain DUF4133 PF13571.6 GAM38605.1 - 0.00018 21.8 1.3 0.17 12.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4133) DUF4191 PF13829.6 GAM38605.1 - 0.0003 20.2 3.8 0.0072 15.7 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4191) TMEM132D_C PF15706.5 GAM38605.1 - 0.015 15.0 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Tfb4 PF03850.14 GAM38605.1 - 0.048 13.1 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF2207 PF09972.9 GAM38605.1 - 0.68 8.6 1.7 3.2 6.4 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) HET PF06985.11 GAM38606.1 - 1.4e-35 122.8 6.4 1.9e-35 122.3 5.3 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_17 PF00332.18 GAM38606.1 - 6e-07 29.4 1.3 9.2e-07 28.7 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DUF3431 PF11913.8 GAM38607.1 - 1.1e-57 195.3 0.0 1.3e-57 195.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Acyl_transf_3 PF01757.22 GAM38608.1 - 8.3e-24 84.3 22.9 2.5e-23 82.7 22.9 1.8 1 1 0 1 1 1 1 Acyltransferase family DUF1624 PF07786.12 GAM38608.1 - 0.00017 21.2 3.1 0.0043 16.7 0.0 3.0 1 1 0 2 2 2 2 Protein of unknown function (DUF1624) Caps_synth_CapC PF14102.6 GAM38608.1 - 0.051 14.0 0.5 0.45 11.0 0.3 2.7 2 0 0 2 2 2 0 Capsule biosynthesis CapC Pal1 PF08316.11 GAM38609.1 - 2.5e-10 41.3 2.8 3.2e-10 40.9 0.1 2.1 2 0 0 2 2 2 1 Pal1 cell morphology protein HVSL PF09749.9 GAM38610.1 - 1.3e-58 198.3 0.0 1.2e-30 106.7 0.0 2.3 1 1 1 2 2 2 2 Uncharacterised conserved protein DUF3807 PF12720.7 GAM38610.1 - 1.8e-33 116.4 11.5 3e-33 115.6 11.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) DUF4604 PF15377.6 GAM38610.1 - 0.16 12.4 9.4 0.38 11.2 9.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) eIF-3_zeta PF05091.12 GAM38613.1 - 0.098 11.6 15.2 0.084 11.8 15.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 GAM38613.1 - 0.1 11.4 12.8 0.096 11.4 12.8 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 GAM38613.1 - 0.19 9.8 11.7 0.16 10.1 11.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 GAM38613.1 - 0.22 9.7 14.1 0.22 9.8 14.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 GAM38613.1 - 0.36 11.0 9.5 0.37 10.9 9.5 1.1 1 0 0 1 1 1 0 DDHD domain Borrelia_P83 PF05262.11 GAM38613.1 - 0.37 9.2 15.0 0.41 9.1 15.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 GAM38613.1 - 0.37 10.1 12.4 0.41 10.0 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Coilin_N PF15862.5 GAM38613.1 - 0.45 10.3 15.3 0.84 9.4 15.3 1.5 1 0 0 1 1 1 0 Coilin N-terminus RR_TM4-6 PF06459.12 GAM38613.1 - 0.5 10.1 14.9 0.6 9.9 14.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 GAM38613.1 - 0.56 10.4 10.6 0.87 9.8 10.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal EOS1 PF12326.8 GAM38613.1 - 0.6 10.0 5.7 0.6 10.0 5.7 1.2 1 0 0 1 1 1 0 N-glycosylation protein DUF2828 PF11443.8 GAM38613.1 - 1.2 7.2 16.0 1.4 6.9 16.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Ureide_permease PF07168.11 GAM38613.1 - 1.2 7.8 2.0 1.1 7.9 2.0 1.1 1 0 0 1 1 1 0 Ureide permease Neur_chan_memb PF02932.16 GAM38613.1 - 1.4 8.9 7.9 1.6 8.7 7.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 GAM38613.1 - 1.7 8.2 24.6 2.4 7.7 24.6 1.2 1 0 0 1 1 1 0 Spt20 family PcfK PF14058.6 GAM38613.1 - 2.8 8.2 16.4 4.4 7.6 16.4 1.4 1 1 0 1 1 1 0 PcfK-like protein SID-1_RNA_chan PF13965.6 GAM38613.1 - 2.9 6.2 4.4 2.5 6.4 4.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3987 PF13148.6 GAM38613.1 - 3.1 6.7 12.4 3.9 6.4 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) PUCC PF03209.15 GAM38613.1 - 3.2 6.7 4.5 3.3 6.6 3.6 1.4 1 1 0 1 1 1 0 PUCC protein PBP_sp32 PF07222.12 GAM38613.1 - 3.2 7.1 13.1 4.1 6.8 13.1 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Connexin PF00029.19 GAM38613.1 - 3.2 7.4 13.0 4.9 6.9 13.0 1.3 1 0 0 1 1 1 0 Connexin Kei1 PF08552.11 GAM38613.1 - 3.2 7.6 4.9 4.4 7.1 4.9 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Paramyxo_ncap PF00973.19 GAM38613.1 - 4.1 6.2 9.4 4.5 6.1 9.4 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1943 PF09172.11 GAM38613.1 - 4.8 6.3 6.8 5.8 6.1 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) V_ATPase_I PF01496.19 GAM38613.1 - 5 4.9 13.1 6 4.6 13.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EIIBC-GUT_N PF03612.14 GAM38613.1 - 5.1 6.8 8.7 7.9 6.2 8.7 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus ALMT PF11744.8 GAM38613.1 - 7.2 5.3 10.3 8 5.2 10.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter NARP1 PF12569.8 GAM38613.1 - 7.3 5.4 17.5 9 5.1 17.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1764 PF08576.10 GAM38613.1 - 9.7 7.2 18.2 3.3 8.7 15.3 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) bZIP_1 PF00170.21 GAM38614.1 - 0.00018 21.5 9.8 0.027 14.6 1.1 3.6 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 GAM38614.1 - 0.002 18.1 19.1 0.028 14.5 1.4 4.0 4 0 0 4 4 4 2 Basic region leucine zipper Coat_F PF07875.12 GAM38614.1 - 0.13 12.5 2.2 0.32 11.3 0.9 2.2 2 0 0 2 2 2 0 Coat F domain CENP-F_leu_zip PF10473.9 GAM38614.1 - 0.23 11.5 14.5 0.23 11.5 1.1 3.3 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mto2_bdg PF12808.7 GAM38614.1 - 0.27 11.5 7.9 0.82 10.0 0.4 3.2 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DivIC PF04977.15 GAM38614.1 - 1 9.2 10.6 0.57 10.0 0.1 3.5 3 1 1 4 4 4 0 Septum formation initiator Cnn_1N PF07989.11 GAM38614.1 - 1 9.5 12.3 0.23 11.6 0.2 3.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Shugoshin_N PF07558.11 GAM38614.1 - 1.5 8.7 11.4 7.6 6.5 0.2 3.8 4 0 0 4 4 3 0 Shugoshin N-terminal coiled-coil region NYD-SP28_assoc PF14775.6 GAM38614.1 - 1.5 8.9 4.4 23 5.2 0.3 3.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain KIAA1430 PF13879.6 GAM38614.1 - 2.1 9.2 10.4 0.34 11.7 5.0 2.5 1 1 1 2 2 2 0 KIAA1430 homologue PRKG1_interact PF15898.5 GAM38614.1 - 2.2 9.2 18.5 2.6 9.0 4.9 3.6 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Spc24 PF08286.11 GAM38614.1 - 2.8 8.2 13.9 5.8 7.2 0.4 3.6 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Lzipper-MIP1 PF14389.6 GAM38614.1 - 3.4 8.0 16.7 3.2 8.1 4.5 4.7 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF4472 PF14739.6 GAM38614.1 - 6.5 7.5 13.2 3.8 8.3 0.3 3.6 2 1 1 4 4 4 0 Domain of unknown function (DUF4472) SOGA PF11365.8 GAM38614.1 - 7.4 7.8 9.8 4 8.6 0.8 3.2 1 1 3 4 4 4 0 Protein SOGA GIT_CC PF16559.5 GAM38614.1 - 8.8 6.3 13.4 11 6.0 2.0 4.1 3 1 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fungal_trans PF04082.18 GAM38615.1 - 5.9e-09 35.4 0.3 3.9e-08 32.7 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM38615.1 - 5.2e-07 29.7 9.4 5.2e-07 29.7 9.4 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DLH PF01738.18 GAM38616.1 - 1.6e-30 106.3 0.2 1.9e-30 106.0 0.2 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF915 PF06028.11 GAM38616.1 - 0.01 15.2 0.0 0.039 13.3 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 GAM38616.1 - 0.02 14.6 0.0 0.058 13.0 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Sugar_tr PF00083.24 GAM38617.1 - 3e-28 98.9 3.8 4.7e-21 75.2 0.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter F-box-like PF12937.7 GAM38618.1 - 7.8e-07 28.9 0.0 1.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM38618.1 - 0.036 14.0 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 F-box domain DJ-1_PfpI PF01965.24 GAM38619.1 - 4.4e-14 52.6 0.0 6.1e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family p450 PF00067.22 GAM38620.1 - 3.1e-27 95.4 0.0 3.5e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RSN1_7TM PF02714.15 GAM38620.1 - 0.014 14.7 0.1 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate AA_permease_2 PF13520.6 GAM38621.1 - 2.2e-29 102.5 49.1 5.8e-27 94.6 49.1 2.1 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM38621.1 - 3.2e-09 35.9 44.1 1.9e-06 26.7 15.8 2.6 2 1 0 2 2 2 2 Amino acid permease VIT1 PF01988.19 GAM38621.1 - 2.5 7.9 9.6 0.95 9.3 0.6 2.9 2 1 0 2 2 2 0 VIT family Hydrolase_4 PF12146.8 GAM38622.1 - 2e-08 33.8 0.0 0.0036 16.6 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM38622.1 - 3e-08 33.6 0.1 1.1e-07 31.8 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM38622.1 - 1e-07 31.7 0.0 0.0065 16.0 0.1 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAM38622.1 - 2.9e-05 24.8 1.2 0.00011 22.9 1.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAM38622.1 - 0.0003 20.4 0.0 0.0005 19.7 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 GAM38622.1 - 0.011 15.6 0.2 0.015 15.1 0.2 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 GAM38622.1 - 0.019 15.1 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain VirJ PF06057.11 GAM38622.1 - 0.095 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.7 GAM38622.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family ERO1 PF04137.15 GAM38623.1 - 4.5e-135 450.4 0.0 5.7e-135 450.1 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Peroxin-13_N PF04088.13 GAM38624.1 - 8.4e-53 178.6 0.2 1.2e-52 178.0 0.2 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 GAM38624.1 - 5.2e-09 35.7 0.0 8.8e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM38624.1 - 8e-08 31.8 0.0 1.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain MFS_1 PF07690.16 GAM38625.1 - 6.3e-26 91.1 38.8 6.3e-26 91.1 38.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 GAM38626.1 - 7.8e-37 127.0 57.0 8.4e-36 123.6 57.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM38626.1 - 9.2e-14 50.8 14.1 9.2e-14 50.8 14.1 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM38626.1 - 7.3e-12 44.9 7.6 7.3e-12 44.9 7.6 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter Gram_pos_anchor PF00746.21 GAM38626.1 - 2.5 8.1 8.5 17 5.5 0.7 3.9 3 0 0 3 3 3 0 LPXTG cell wall anchor motif MFS_1 PF07690.16 GAM38627.1 - 2.4e-17 62.9 34.9 2.4e-17 62.9 34.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily APG6 PF04111.12 GAM38628.1 - 2.7e-74 249.0 0.0 3.8e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 GAM38628.1 - 6.5e-41 140.0 14.0 1.1e-40 139.2 14.0 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region Sds3 PF08598.11 GAM38628.1 - 0.00098 19.2 0.8 0.0015 18.6 0.8 1.4 1 0 0 1 1 1 1 Sds3-like KASH_CCD PF14662.6 GAM38628.1 - 0.037 13.9 9.9 0.042 13.7 8.4 1.7 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 GAM38628.1 - 0.98 8.7 7.2 2 7.6 7.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Lge1 PF11488.8 GAM38628.1 - 1.2 9.4 8.4 2 8.7 6.9 2.1 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Jnk-SapK_ap_N PF09744.9 GAM38628.1 - 2 8.7 12.0 62 3.8 13.6 2.4 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 CENP-H PF05837.12 GAM38628.1 - 6.7 7.2 8.5 2 8.8 5.2 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Scm3 PF10384.9 GAM38629.1 - 2.2e-20 72.1 0.3 4.8e-20 71.0 0.3 1.6 1 0 0 1 1 1 1 Centromere protein Scm3 PALP PF00291.25 GAM38630.1 - 3e-62 210.7 0.1 4.3e-62 210.2 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.17 GAM38631.1 - 1.5e-41 142.8 0.0 2.4e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PX PF00787.24 GAM38633.1 - 1.6e-16 60.3 0.0 2.8e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 PX domain MFS_1 PF07690.16 GAM38634.1 - 2.1e-36 125.6 30.7 2.9e-36 125.1 30.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM38634.1 - 1.2e-05 24.9 4.2 1.2e-05 24.9 4.2 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 GAM38634.1 - 3.4e-05 22.9 14.1 0.0011 18.0 1.2 2.7 1 1 1 2 2 2 2 Sugar (and other) transporter IQ PF00612.27 GAM38634.1 - 5e-05 22.7 1.0 0.00013 21.4 1.0 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif MFS_1_like PF12832.7 GAM38634.1 - 0.0023 16.9 7.9 0.0036 16.2 7.9 1.3 1 0 0 1 1 1 1 MFS_1 like family DUF3659 PF12396.8 GAM38636.1 - 3.3e-247 798.8 165.5 2.6e-25 88.1 3.2 12.9 13 0 0 13 13 13 12 Protein of unknown function (DUF3659) Clavanin PF05452.11 GAM38636.1 - 0.016 15.4 0.0 0.2 11.9 0.0 3.0 1 0 0 1 1 1 0 Clavanin RPW8 PF05659.11 GAM38636.1 - 0.024 14.3 1.6 0.13 12.0 0.5 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 IF3_N PF05198.16 GAM38636.1 - 0.066 13.5 0.4 5 7.5 0.0 3.2 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain Eno-Rase_FAD_bd PF07055.12 GAM38636.1 - 0.076 13.4 0.1 0.3 11.5 0.1 2.1 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain 2C_adapt PF08793.10 GAM38636.1 - 0.11 12.7 0.2 1.3 9.2 0.0 3.0 3 0 0 3 3 3 0 2-cysteine adaptor domain CBS PF00571.28 GAM38636.1 - 0.88 10.1 11.7 13 6.3 0.1 5.9 4 0 0 4 4 4 0 CBS domain CSN5_C PF18323.1 GAM38636.1 - 8.3 7.4 8.5 79 4.3 0.0 4.3 3 1 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain Fungal_trans_2 PF11951.8 GAM38637.1 - 0.0078 15.1 0.1 0.01 14.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arteri_GP4 PF02497.15 GAM38637.1 - 0.085 13.0 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Arterivirus glycoprotein Cupin_1 PF00190.22 GAM38638.1 - 7.9e-30 103.5 0.0 7.6e-19 67.8 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 GAM38638.1 - 2.6e-19 68.7 0.3 4.2e-12 45.6 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 GAM38638.1 - 3.3e-07 29.9 0.0 0.0023 17.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 GAM38638.1 - 0.028 14.3 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain DUF1275 PF06912.11 GAM38639.1 - 4.5e-44 150.7 10.3 5.4e-44 150.4 10.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Asp PF00026.23 GAM38640.1 - 1.6e-70 238.0 19.2 2e-70 237.7 19.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 GAM38640.1 - 0.00017 22.2 4.1 0.18 12.5 1.3 2.8 2 1 0 2 2 2 2 Aspartyl protease Triabin PF03973.13 GAM38640.1 - 0.069 13.0 0.2 0.24 11.3 0.1 1.9 2 0 0 2 2 2 0 Triabin TAXi_C PF14541.6 GAM38640.1 - 0.093 12.5 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Ank_2 PF12796.7 GAM38641.1 - 4.9e-38 129.6 13.2 6.2e-09 36.3 0.3 5.8 3 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM38641.1 - 5.9e-31 106.5 7.2 0.00036 21.0 0.0 8.2 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM38641.1 - 1e-23 83.1 10.8 5.7e-05 23.3 0.1 7.5 4 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM38641.1 - 1.5e-22 77.2 8.4 0.0015 18.8 0.4 11.0 11 0 0 11 11 11 4 Ankyrin repeat Ank PF00023.30 GAM38641.1 - 7.4e-22 76.8 18.3 0.00052 20.3 1.1 9.9 9 1 0 9 9 9 5 Ankyrin repeat DUF1601 PF07671.11 GAM38641.1 - 0.056 13.3 0.1 0.18 11.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) DEK_C PF08766.11 GAM38641.1 - 0.23 11.4 0.3 0.44 10.5 0.3 1.4 1 0 0 1 1 1 0 DEK C terminal domain Ank_2 PF12796.7 GAM38642.1 - 1e-38 131.7 0.8 2.2e-10 41.0 0.1 6.5 3 1 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM38642.1 - 1.3e-27 95.8 9.2 2.3e-05 24.9 0.0 8.2 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM38642.1 - 3.2e-27 91.6 9.4 0.016 15.7 0.0 11.9 12 0 0 12 12 12 6 Ankyrin repeat Ank PF00023.30 GAM38642.1 - 1.7e-26 91.5 10.3 0.00011 22.5 0.2 10.4 10 1 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 GAM38642.1 - 2e-25 88.5 9.2 1.2e-05 25.5 0.1 7.8 4 3 4 8 8 8 5 Ankyrin repeats (many copies) F-box PF00646.33 GAM38642.1 - 0.13 12.2 0.6 0.34 10.9 0.6 1.7 1 0 0 1 1 1 0 F-box domain BTB PF00651.31 GAM38643.1 - 0.15 12.3 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Methyltransf_31 PF13847.6 GAM38644.1 - 0.0034 17.2 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM38644.1 - 0.15 12.8 0.0 0.25 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PNP_UDP_1 PF01048.20 GAM38645.1 - 1.9e-05 24.1 0.3 0.00016 21.0 0.3 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 GAM38646.1 - 4.2e-45 152.2 2.1 6.1e-15 55.6 0.0 5.5 2 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM38646.1 - 1.2e-31 105.2 0.1 0.0006 20.1 0.0 9.6 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 GAM38646.1 - 1.3e-30 105.4 0.0 2.4e-09 37.5 0.0 6.7 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM38646.1 - 2e-28 98.0 5.2 3.2e-07 30.5 0.1 7.1 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 GAM38646.1 - 1.9e-23 81.8 5.2 0.0017 18.7 0.0 9.6 8 1 1 9 9 9 5 Ankyrin repeat Plasmodium_Vir PF05795.11 GAM38648.1 - 0.011 15.2 0.2 0.014 14.9 0.2 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SPX PF03105.19 GAM38648.1 - 0.052 13.5 0.7 0.055 13.4 0.7 1.1 1 0 0 1 1 1 0 SPX domain Glyco_hydro_18 PF00704.28 GAM38649.1 - 7.5e-20 71.9 1.1 1.7e-19 70.7 1.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 FMO-like PF00743.19 GAM38650.1 - 4.4e-91 305.9 0.0 5.4e-91 305.6 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAM38650.1 - 1.1e-23 84.0 0.1 2.9e-17 62.9 0.0 3.4 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM38650.1 - 5.5e-15 55.4 0.0 2e-13 50.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM38650.1 - 3.5e-10 39.6 0.1 2e-07 30.5 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAM38650.1 - 3.8e-09 36.6 0.0 1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAM38650.1 - 4.1e-08 33.4 0.6 0.0013 18.8 0.1 3.7 3 1 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 GAM38650.1 - 1.7e-06 27.8 0.1 0.0039 16.8 0.1 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM38650.1 - 2.4e-05 24.8 0.0 0.12 12.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAM38650.1 - 0.00021 20.7 0.0 0.00094 18.6 0.0 2.0 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 GAM38650.1 - 0.00034 19.8 0.0 0.00058 19.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAM38650.1 - 0.001 18.3 0.2 0.019 14.2 0.0 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 GAM38650.1 - 0.0025 16.6 0.0 0.014 14.1 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 GAM38650.1 - 0.0034 16.8 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAM38650.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAM38650.1 - 0.14 11.2 0.2 4 6.4 0.1 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.16 GAM38651.1 - 5e-35 121.1 30.4 7.9e-35 120.4 25.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 GAM38651.1 - 3.1 8.1 9.1 0.43 10.9 1.8 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Peptidase_S9 PF00326.21 GAM38652.1 - 1.1e-48 165.5 0.1 1.2e-47 162.1 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 GAM38652.1 - 0.00095 17.9 0.0 0.29 9.8 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 GAM38652.1 - 0.0032 17.1 0.2 0.043 13.5 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold PD40 PF07676.12 GAM38652.1 - 0.063 13.2 0.0 3.6 7.6 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Amidohydro_2 PF04909.14 GAM38653.1 - 1.8e-41 142.9 0.2 2.2e-41 142.5 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 GAM38653.1 - 0.011 15.1 0.0 0.04 13.3 0.0 1.5 1 1 0 1 1 1 0 TatD related DNase NmrA PF05368.13 GAM38654.1 - 7.6e-15 55.1 0.0 9.3e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM38654.1 - 5.8e-08 32.8 0.0 8.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAM38654.1 - 0.0002 21.6 0.0 0.00034 20.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 GAM38654.1 - 0.0016 17.5 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM38654.1 - 0.095 12.1 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 GAM38655.1 - 2.3e-16 59.7 20.2 8.2e-10 38.1 6.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM38655.1 - 0.031 13.1 8.5 0.016 14.1 3.4 2.1 1 1 1 2 2 2 0 Sugar (and other) transporter RNase_H PF00075.24 GAM38656.1 - 5.4e-09 36.4 0.0 8.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 GAM38656.1 - 0.13 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like Sec63 PF02889.16 GAM38657.1 - 1.6e-166 551.8 0.0 4.6e-94 314.4 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 GAM38657.1 - 1.2e-49 168.4 0.9 9.9e-29 100.3 0.1 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 GAM38657.1 - 6.1e-30 103.7 0.6 1.9e-29 102.1 0.6 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 GAM38657.1 - 3.1e-24 85.9 0.0 2.1e-13 50.7 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAM38657.1 - 1.6e-11 44.5 0.0 1.4e-07 31.9 0.0 3.7 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAM38657.1 - 7.1e-07 29.6 1.1 0.0087 16.3 0.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 GAM38657.1 - 1.1e-06 28.5 0.0 0.00044 20.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAM38657.1 - 0.00071 20.0 0.0 1.4 9.3 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.6 GAM38657.1 - 0.0013 19.1 0.0 1.6 9.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 GAM38657.1 - 0.0022 17.5 0.0 0.18 11.2 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein UvrD-helicase PF00580.21 GAM38657.1 - 0.018 14.6 0.0 1.5 8.3 0.0 2.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 GAM38657.1 - 0.047 12.8 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_11 PF13086.6 GAM38657.1 - 0.098 12.4 0.0 21 4.8 0.0 2.9 2 1 1 3 3 3 0 AAA domain DUF2075 PF09848.9 GAM38657.1 - 0.12 11.6 0.0 3.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MutS_V PF00488.21 GAM38658.1 - 2.9e-73 245.9 0.0 5.6e-73 245.0 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAM38658.1 - 8.8e-43 146.8 6.0 2.1e-42 145.5 6.0 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 GAM38658.1 - 8.2e-21 74.4 0.0 2e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 GAM38658.1 - 3.6e-06 27.3 0.0 1e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_28 PF13521.6 GAM38658.1 - 0.038 14.2 0.7 2.2 8.5 0.0 3.7 4 0 0 4 4 4 0 AAA domain MutS_IV PF05190.18 GAM38658.1 - 0.042 14.2 0.2 0.1 13.0 0.2 1.8 1 0 0 1 1 1 0 MutS family domain IV AAA_23 PF13476.6 GAM38658.1 - 1.6 9.2 5.2 3.8 8.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain Ureidogly_lyase PF04115.12 GAM38659.1 - 8.2e-61 205.0 0.0 2.4e-29 102.5 0.0 2.1 2 0 0 2 2 2 2 Ureidoglycolate lyase AMP-binding PF00501.28 GAM38660.1 - 2.7e-66 223.9 0.0 8.8e-44 149.8 0.0 2.0 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 GAM38660.1 - 1.2e-15 58.3 0.3 6.3e-15 55.9 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 GAM38661.1 - 2.6e-23 82.4 0.9 4.1e-23 81.8 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rhodanese PF00581.20 GAM38661.1 - 0.085 13.4 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Rhodanese-like domain ETX_MTX2 PF03318.13 GAM38663.1 - 2e-10 40.8 7.6 2.7e-10 40.4 7.6 1.1 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.20 GAM38663.1 - 5.2e-08 32.5 1.1 6.6e-08 32.2 1.1 1.1 1 0 0 1 1 1 1 Aerolysin toxin PA14 PF07691.12 GAM38663.1 - 0.027 14.3 0.3 0.052 13.4 0.2 1.5 1 1 0 1 1 1 0 PA14 domain Herpes_capsid PF06112.11 GAM38664.1 - 0.081 13.0 2.0 0.12 12.4 2.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein HET PF06985.11 GAM38666.1 - 5.8e-05 23.5 3.4 0.0065 16.8 0.3 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Brix PF04427.18 GAM38668.1 - 8.7e-31 107.5 0.0 1.3e-30 106.9 0.0 1.3 1 0 0 1 1 1 1 Brix domain Tim17 PF02466.19 GAM38668.1 - 2.7e-11 43.8 0.3 4.6e-11 43.1 0.3 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RNase_P_p30 PF01876.16 GAM38670.1 - 4.8e-66 222.3 0.0 6.4e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Pkinase PF00069.25 GAM38671.1 - 6.7e-65 219.1 0.2 7.8e-65 218.9 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM38671.1 - 1.6e-19 70.2 0.0 2.3e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM38671.1 - 6.6e-08 32.8 0.0 7.3e-05 22.8 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAM38671.1 - 0.0036 16.2 0.0 0.0069 15.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAM38671.1 - 0.0074 15.6 0.0 0.015 14.7 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM38671.1 - 0.023 14.1 0.3 0.037 13.4 0.3 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 GAM38671.1 - 0.064 12.8 0.1 0.064 12.8 0.1 2.0 3 0 0 3 3 3 0 Choline/ethanolamine kinase tRNA-synt_1 PF00133.22 GAM38672.1 - 7e-216 718.1 0.3 7e-216 718.1 0.3 2.3 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAM38672.1 - 1.7e-33 115.7 1.6 1.7e-33 115.7 1.6 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAM38672.1 - 1.3e-15 57.1 2.6 2.9e-06 26.3 0.1 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAM38672.1 - 4.9e-09 36.0 2.9 3.4e-06 26.7 0.0 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 GAM38672.1 - 0.0032 16.9 0.0 0.61 9.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 GAM38672.1 - 0.0059 16.9 6.5 0.0059 16.9 6.5 3.2 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm DUF4028 PF13220.6 GAM38672.1 - 0.075 12.8 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) DUF4149 PF13664.6 GAM38674.1 - 1 9.7 9.3 3.9 7.8 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) Acetyltransf_1 PF00583.25 GAM38675.1 - 2.9e-09 37.2 0.0 3.6e-09 36.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM38675.1 - 5.7e-08 33.1 0.0 8.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM38675.1 - 2.2e-07 30.9 0.0 3.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM38675.1 - 0.0057 16.7 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.6 GAM38676.1 - 4.4e-54 183.9 43.0 5.8e-54 183.5 43.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM38676.1 - 2.5e-24 85.7 44.7 1.3e-23 83.4 44.7 1.8 1 1 0 1 1 1 1 Amino acid permease Sec62 PF03839.16 GAM38676.1 - 0.033 13.7 3.6 0.077 12.5 3.6 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 PAN_3 PF08277.12 GAM38677.1 - 0.14 12.0 0.7 0.26 11.1 0.7 1.4 1 0 0 1 1 1 0 PAN-like domain Sugar_tr PF00083.24 GAM38678.1 - 5.3e-84 282.7 24.3 6.3e-84 282.4 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM38678.1 - 1.3e-15 57.2 35.0 2e-11 43.4 8.9 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAM38678.1 - 0.00071 18.5 4.7 0.00071 18.5 4.7 2.4 2 1 0 2 2 2 2 MFS_1 like family ADH_zinc_N PF00107.26 GAM38680.1 - 1.3e-13 51.0 0.4 2.5e-13 50.1 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM38680.1 - 5.5e-05 23.0 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 GAM38680.1 - 0.011 15.7 0.7 0.017 15.0 0.7 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 GAM38680.1 - 0.027 14.0 0.8 0.041 13.4 0.8 1.2 1 0 0 1 1 1 0 NmrA-like family DapB_N PF01113.20 GAM38680.1 - 0.094 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N_2 PF13602.6 GAM38680.1 - 0.11 13.6 0.1 0.5 11.4 0.0 1.9 1 1 1 2 2 2 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAM38680.1 - 0.2 11.0 6.0 0.32 10.3 6.0 1.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1028 PF06267.12 GAM38680.1 - 0.26 11.1 3.4 0.4 10.4 3.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF1028) CDP-OH_P_transf PF01066.21 GAM38681.1 - 2.1e-15 57.3 0.3 2.1e-15 57.3 0.3 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_M1_N PF17900.1 GAM38682.1 - 3.6e-06 27.3 0.0 0.016 15.4 0.0 2.5 1 1 0 2 2 2 2 Peptidase M1 N-terminal domain LSM PF01423.22 GAM38683.1 - 2.4e-22 78.4 0.5 2.6e-22 78.3 0.5 1.0 1 0 0 1 1 1 1 LSM domain LtrA PF06772.11 GAM38685.1 - 3.6e-19 69.2 17.9 3.6e-19 69.2 17.9 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) DLIC PF05783.11 GAM38685.1 - 0.078 11.8 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SRTM1 PF15872.5 GAM38685.1 - 0.49 10.6 2.3 3.7 7.7 0.2 2.9 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 Ank_2 PF12796.7 GAM38686.1 - 3.1e-65 216.8 9.3 3.3e-15 56.4 0.0 7.4 6 2 1 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM38686.1 - 1.6e-45 152.9 9.7 2e-11 44.2 0.1 10.5 5 3 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM38686.1 - 8.8e-45 150.2 15.9 3.4e-10 40.0 0.2 11.0 8 3 4 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM38686.1 - 4.3e-41 134.2 12.1 9.1e-06 25.7 0.0 13.0 15 0 0 15 15 15 7 Ankyrin repeat Ank PF00023.30 GAM38686.1 - 1.3e-39 133.0 18.8 3.4e-05 24.1 0.6 11.5 12 0 0 12 12 12 9 Ankyrin repeat DUF1843 PF08898.10 GAM38686.1 - 1.1 9.9 5.0 21 5.7 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) zf-C2H2 PF00096.26 GAM38687.1 - 1.6e-05 25.1 18.4 0.14 12.6 0.2 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM38687.1 - 0.096 13.6 18.7 1.1 10.3 0.3 5.0 4 1 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 GAM38687.1 - 0.16 12.6 7.9 1.5 9.5 1.1 3.6 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 GAM38687.1 - 0.29 11.6 1.9 6.6 7.3 0.6 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAM38687.1 - 5.9 7.3 6.6 5 7.5 0.6 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.25 GAM38688.1 - 1.5e-38 132.7 0.0 1.5e-20 73.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM38688.1 - 7.9e-14 51.6 0.0 9.7e-06 25.0 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase SpoIIE PF07228.12 GAM38688.1 - 1.2e-11 44.9 0.0 4.5e-11 43.0 0.1 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GAM38688.1 - 1.2e-10 41.4 0.3 3e-10 40.1 0.3 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 GAM38688.1 - 4.8e-07 29.7 0.1 0.023 14.3 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Kinase-like PF14531.6 GAM38688.1 - 0.0072 15.7 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 GAM38688.1 - 0.021 14.7 0.0 0.061 13.2 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family CAP_GLY PF01302.25 GAM38689.1 - 1.5e-15 57.0 0.7 3.1e-15 55.9 0.7 1.6 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 GAM38689.1 - 4e-09 36.1 10.7 5e-05 23.1 0.9 2.7 2 0 0 2 2 2 2 CLIP1 zinc knuckle TPR_MLP1_2 PF07926.12 GAM38689.1 - 0.004 17.2 15.8 0.004 17.2 15.8 3.7 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein Spectrin PF00435.21 GAM38689.1 - 0.0087 16.5 23.3 0.07 13.6 6.3 3.4 1 1 1 3 3 3 1 Spectrin repeat AAA_13 PF13166.6 GAM38689.1 - 0.01 14.5 20.0 0.018 13.7 9.8 2.9 2 1 1 3 3 3 0 AAA domain ASL_C PF08328.11 GAM38689.1 - 0.034 14.2 0.4 0.086 12.9 0.4 1.6 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal ATG16 PF08614.11 GAM38689.1 - 0.057 13.6 35.1 11 6.2 15.7 3.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 GAM38689.1 - 0.062 13.3 15.6 0.63 10.1 2.9 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.11 GAM38689.1 - 0.14 11.9 20.2 0.71 9.7 4.5 3.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 GAM38689.1 - 0.27 11.7 12.2 0.33 11.4 1.6 3.4 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein Peptidase_S46 PF10459.9 GAM38689.1 - 0.37 9.4 10.4 0.51 8.9 10.4 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF4094 PF13334.6 GAM38689.1 - 0.49 10.8 7.3 1.1 9.7 0.0 3.8 3 2 0 3 3 3 0 Domain of unknown function (DUF4094) DUF812 PF05667.11 GAM38689.1 - 0.61 8.9 25.7 0.5 9.2 16.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF812) Spc7 PF08317.11 GAM38689.1 - 0.82 8.5 34.3 0.79 8.5 8.9 3.0 1 1 1 3 3 3 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 GAM38689.1 - 1 9.7 21.1 1.5 9.2 3.4 4.4 4 1 0 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 C1_2 PF03107.16 GAM38689.1 - 1.3 9.4 4.2 11 6.4 0.3 2.4 2 0 0 2 2 2 0 C1 domain SlyX PF04102.12 GAM38689.1 - 1.6 9.4 27.7 18 6.1 8.4 4.1 4 1 0 4 4 3 0 SlyX DUF3584 PF12128.8 GAM38689.1 - 2.1 5.8 27.0 3.1 5.2 27.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 GAM38689.1 - 2.5 7.4 25.1 5.5e+03 -3.6 25.1 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 GAM38689.1 - 2.6 7.3 19.9 0.67 9.3 9.1 3.3 3 1 0 3 3 3 0 FAM76 protein Fez1 PF06818.15 GAM38689.1 - 2.6 8.5 33.3 0.31 11.5 17.3 3.6 2 1 2 4 4 4 0 Fez1 DUF16 PF01519.16 GAM38689.1 - 3.9 8.0 24.4 3 8.4 0.3 4.8 2 1 3 5 5 4 0 Protein of unknown function DUF16 TolA_bind_tri PF16331.5 GAM38689.1 - 6.4 6.9 34.4 2.4 8.3 4.2 4.4 2 1 1 4 4 3 0 TolA binding protein trimerisation Spc29 PF17082.5 GAM38689.1 - 7.3 6.4 17.4 5.5 6.8 1.4 3.4 1 1 1 3 3 3 0 Spindle Pole Component 29 FlaC_arch PF05377.11 GAM38689.1 - 8.1 6.9 12.0 6.2 7.3 0.7 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 GAM38689.1 - 9.7 6.0 22.3 0.56 10.0 4.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) 3-HAO PF06052.12 GAM38690.1 - 6.5e-53 178.4 0.0 7.6e-53 178.2 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 GAM38690.1 - 0.00052 19.7 0.0 0.00092 18.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 GAM38690.1 - 0.0014 18.3 0.1 0.0022 17.6 0.1 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 GAM38690.1 - 0.052 13.4 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Zn-ribbon_8 PF09723.10 GAM38690.1 - 0.26 11.5 0.3 0.26 11.5 0.3 1.9 2 0 0 2 2 2 0 Zinc ribbon domain RTC_insert PF05189.13 GAM38691.1 - 1.4e-30 105.9 0.0 2.6e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 GAM38691.1 - 3.7e-28 98.3 0.1 4.7e-28 97.9 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase FAD_binding_3 PF01494.19 GAM38693.1 - 1.5e-15 57.3 0.0 1.1e-14 54.5 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM38693.1 - 2.7e-07 30.5 0.0 0.005 16.5 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM38693.1 - 8.2e-06 26.0 0.0 2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM38693.1 - 0.0089 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM38693.1 - 0.03 13.6 0.0 0.085 12.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 GAM38693.1 - 0.053 13.2 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 GAM38693.1 - 0.075 13.0 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAM38693.1 - 0.082 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM38693.1 - 0.13 11.0 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 GAM38693.1 - 0.22 11.5 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ank_2 PF12796.7 GAM38694.1 - 2.8e-104 341.9 22.4 7.1e-13 49.0 0.3 13.6 6 5 6 14 14 14 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM38694.1 - 2.9e-82 270.1 22.0 4e-09 36.8 0.1 17.8 11 5 6 17 17 17 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM38694.1 - 9.3e-63 200.8 24.7 0.00013 22.2 0.0 26.0 27 0 0 27 27 26 12 Ankyrin repeat Ank_5 PF13857.6 GAM38694.1 - 1.1e-51 172.2 29.5 1.7e-06 28.2 0.1 18.8 9 5 10 20 20 20 10 Ankyrin repeats (many copies) Ank PF00023.30 GAM38694.1 - 1.9e-41 138.7 58.8 0.011 16.1 0.3 24.4 25 1 1 26 26 26 12 Ankyrin repeat NACHT PF05729.12 GAM38694.1 - 5.6e-13 49.1 0.0 4e-12 46.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Fungal_trans PF04082.18 GAM38694.1 - 9.7e-11 41.2 0.4 1.1e-09 37.7 0.3 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain AAA_16 PF13191.6 GAM38694.1 - 3.2e-06 27.6 0.0 1.4e-05 25.6 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT_N PF17100.5 GAM38694.1 - 6.6e-05 22.9 0.3 0.00018 21.4 0.3 1.7 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_22 PF13401.6 GAM38694.1 - 0.00063 20.0 0.0 0.0029 17.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAM38694.1 - 0.002 17.4 0.0 0.0042 16.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 GAM38694.1 - 0.003 18.1 0.0 0.024 15.1 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 GAM38694.1 - 0.0082 16.3 0.0 0.09 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAM38694.1 - 0.0093 15.7 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAM38694.1 - 0.016 15.6 0.0 0.041 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 GAM38694.1 - 0.019 14.9 0.0 0.065 13.1 0.0 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 GAM38694.1 - 0.058 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 GAM38694.1 - 0.085 13.2 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1843 PF08898.10 GAM38694.1 - 1.8 9.1 10.6 57 4.3 0.1 5.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) AA_permease PF00324.21 GAM38695.1 - 3.7e-107 358.9 37.5 4.6e-107 358.6 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM38695.1 - 1.8e-28 99.6 35.3 2.5e-28 99.1 35.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3392 PF11872.8 GAM38695.1 - 0.13 12.5 12.5 0.23 11.8 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3392) RGS PF00615.19 GAM38697.1 - 3.6e-12 46.6 0.0 5.5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Neuraminidase PF18413.1 GAM38698.1 - 0.31 10.7 0.2 0.44 10.2 0.2 1.1 1 0 0 1 1 1 0 Neuraminidase-like domain Herpes_LMP1 PF05297.11 GAM38698.1 - 4.6 6.3 9.5 5.4 6.1 9.5 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1700 PF08006.11 GAM38698.1 - 5.4 6.5 10.6 4.4 6.8 9.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) DUF3810 PF12725.7 GAM38698.1 - 5.6 6.2 5.7 7.1 5.9 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) T5orf172 PF10544.9 GAM38699.1 - 8e-24 84.1 0.5 3.4e-23 82.1 0.5 2.2 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 GAM38699.1 - 7.4e-18 65.0 2.8 1.3e-17 64.2 1.4 2.2 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 GIY-YIG PF01541.24 GAM38699.1 - 0.12 12.7 1.1 0.28 11.5 0.3 2.0 2 0 0 2 2 2 0 GIY-YIG catalytic domain DUF3431 PF11913.8 GAM38700.1 - 3.3e-91 304.9 0.2 4e-91 304.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Beta-lactamase PF00144.24 GAM38701.1 - 1.3e-31 110.1 3.5 2.6e-31 109.1 3.2 1.6 2 0 0 2 2 2 1 Beta-lactamase zf-rbx1 PF12678.7 GAM38702.1 - 1.7e-10 41.0 3.9 3e-10 40.2 3.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAM38702.1 - 5.4e-08 33.1 8.2 1.8e-07 31.4 8.2 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAM38702.1 - 3.7e-07 29.9 2.6 6.6e-07 29.1 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM38702.1 - 1.4e-05 25.0 1.8 2.8e-05 24.0 1.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAM38702.1 - 2.3e-05 24.1 6.5 0.00013 21.8 2.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM38702.1 - 5.8e-05 23.0 2.6 0.00021 21.2 2.8 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAM38702.1 - 8e-05 22.4 3.4 0.0002 21.2 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAM38702.1 - 0.00016 21.2 1.0 0.00034 20.2 1.0 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GAM38702.1 - 0.0016 18.4 4.6 0.0068 16.4 4.6 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAM38702.1 - 0.0061 16.4 5.5 0.017 15.0 5.6 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 GAM38702.1 - 0.038 13.7 1.9 0.43 10.4 0.2 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 GAM38702.1 - 0.079 13.1 0.9 0.16 12.2 0.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-3CxxC_2 PF17180.4 GAM38702.1 - 0.28 11.9 1.6 17 6.3 0.4 2.5 1 1 1 2 2 2 0 Zinc-binding domain FANCL_C PF11793.8 GAM38702.1 - 2.1 8.6 3.9 11 6.2 3.9 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain MFS_1 PF07690.16 GAM38703.1 - 4.2e-22 78.6 31.3 1.2e-10 40.9 3.8 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.8 GAM38703.1 - 0.00017 20.4 0.1 0.0037 16.0 0.0 2.3 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_2 PF13347.6 GAM38703.1 - 0.00029 19.5 21.1 0.0015 17.1 3.9 3.8 4 0 0 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.7 GAM38703.1 - 0.00053 19.0 1.7 0.24 10.2 0.0 3.0 3 1 0 3 3 3 2 MFS_1 like family Heliorhodopsin PF18761.1 GAM38703.1 - 0.02 14.2 0.2 0.11 11.8 0.0 2.2 3 0 0 3 3 3 0 Heliorhodopsin ATP_transf PF09830.9 GAM38704.1 - 2.7e-23 81.9 0.0 6.2e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase Trypan_PARP PF05887.11 GAM38705.1 - 5.5 7.0 14.4 10 6.1 14.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 GAM38705.1 - 7.6 6.1 12.5 13 5.3 12.5 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) RPN7 PF10602.9 GAM38706.1 - 8.9e-47 159.0 0.2 2e-46 157.9 0.0 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 GAM38706.1 - 2.4e-13 50.5 0.3 9.6e-12 45.3 0.0 3.0 2 1 1 3 3 3 1 PCI domain TPR_14 PF13428.6 GAM38706.1 - 0.035 14.9 0.9 22 6.2 0.6 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAM38706.1 - 0.62 10.7 6.2 17 6.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DSBA PF01323.20 GAM38707.1 - 1e-11 45.0 0.0 1.3e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF2336 PF10098.9 GAM38707.1 - 0.0085 15.6 0.1 0.011 15.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2336) adh_short PF00106.25 GAM38708.1 - 1.4e-24 86.7 0.0 1.8e-15 56.9 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM38708.1 - 2.6e-20 73.0 0.1 2.1e-15 56.9 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 GAM38708.1 - 0.0044 16.4 0.0 0.24 10.8 0.0 2.8 3 0 0 3 3 3 1 Fungal family of unknown function (DUF1776) KR PF08659.10 GAM38708.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 GAM38708.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 GAM38708.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain BTB PF00651.31 GAM38709.1 - 0.0057 16.9 0.7 0.87 9.8 0.0 3.0 3 0 0 3 3 3 2 BTB/POZ domain Fungal_trans PF04082.18 GAM38710.1 - 3.4e-12 46.0 1.8 6.9e-12 45.0 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM38710.1 - 1.1e-08 35.1 10.6 2e-08 34.2 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1110 PF06533.12 GAM38710.1 - 0.026 14.5 0.6 0.059 13.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) ABATE PF07336.11 GAM38710.1 - 0.028 15.1 0.1 0.13 13.0 0.0 2.1 2 1 0 2 2 2 0 Putative stress-induced transcription regulator FATC PF02260.20 GAM38710.1 - 0.059 13.2 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 FATC domain adh_short PF00106.25 GAM38711.1 - 1.5e-27 96.3 0.0 2e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM38711.1 - 3.1e-23 82.6 0.0 3.6e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM38711.1 - 3e-07 30.5 0.0 5.1e-07 29.8 0.0 1.4 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 GAM38711.1 - 0.042 13.7 0.0 0.059 13.2 0.0 1.3 1 1 0 1 1 1 0 NAD(P)H-binding DUF2857 PF11198.8 GAM38712.1 - 0.079 12.7 0.0 0.079 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) DUF1768 PF08719.11 GAM38713.1 - 3.5e-51 173.6 0.1 4e-51 173.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Aldo_ket_red PF00248.21 GAM38714.1 - 1e-39 136.5 0.0 3.1e-37 128.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family HSCB_C PF07743.13 GAM38715.1 - 1.9e-19 69.9 2.1 5.1e-19 68.5 1.1 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 GAM38715.1 - 1.5e-05 25.1 0.0 3.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 GAM38716.1 - 3.8e-36 122.5 19.3 2.3e-08 34.5 2.3 7.9 7 1 0 7 7 7 5 WD domain, G-beta repeat PRP4 PF08799.11 GAM38716.1 - 7.5e-15 54.2 6.2 1.4e-14 53.3 6.2 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 GAM38716.1 - 3.9e-12 46.3 0.1 0.032 14.5 0.0 5.6 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM38716.1 - 0.0051 15.8 0.0 11 4.9 0.0 4.1 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAM38716.1 - 0.028 13.7 0.0 0.2 11.0 0.0 2.4 4 1 0 4 4 4 0 WD40-like domain PWWP PF00855.17 GAM38717.1 - 1.5e-16 60.6 0.0 1.5e-16 60.6 0.0 3.6 2 1 1 3 3 3 1 PWWP domain PAP2_3 PF14378.6 GAM38718.1 - 4.1e-33 114.7 16.5 4.8e-16 59.0 0.2 3.3 3 0 0 3 3 3 3 PAP2 superfamily PAP2 PF01569.21 GAM38718.1 - 0.0048 16.7 1.5 0.0048 16.7 1.5 2.6 3 0 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 GAM38718.1 - 0.69 10.5 4.4 0.38 11.3 0.7 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal TPR_10 PF13374.6 GAM38719.1 - 4.9e-49 162.9 2.0 5e-10 38.9 0.0 5.7 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAM38719.1 - 8.3e-41 138.2 4.9 8e-15 54.9 0.1 5.2 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAM38719.1 - 1e-14 53.4 1.8 0.043 13.9 0.1 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 GAM38719.1 - 1.5e-11 44.0 0.0 2.9e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.22 GAM38719.1 - 1.4e-10 40.8 0.0 3.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.6 GAM38719.1 - 2.9e-10 39.5 0.3 0.01 16.0 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM38719.1 - 4.4e-10 38.9 5.1 0.13 12.4 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM38719.1 - 1.4e-09 37.3 1.3 0.054 13.3 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM38719.1 - 1e-08 35.6 1.7 0.041 14.4 0.0 5.9 7 2 2 9 9 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 GAM38719.1 - 7.8e-08 32.2 0.9 0.027 15.1 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM38719.1 - 2.8e-07 30.2 0.9 2.8e-07 30.2 0.9 2.2 2 1 0 2 2 2 1 MalT-like TPR region TPR_16 PF13432.6 GAM38719.1 - 1.2e-06 29.1 0.4 0.0075 16.9 0.0 4.1 4 1 1 5 5 3 1 Tetratricopeptide repeat NACHT PF05729.12 GAM38719.1 - 1.4e-06 28.4 0.0 4.3e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_14 PF13428.6 GAM38719.1 - 7.1e-06 26.4 0.2 4.3 8.4 0.0 6.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM38719.1 - 3e-05 24.1 1.9 12 6.6 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM38719.1 - 0.00016 22.1 1.2 15 6.5 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat LPD13 PF18825.1 GAM38719.1 - 0.0016 18.2 0.1 0.003 17.3 0.1 1.4 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 13 AAA_16 PF13191.6 GAM38719.1 - 0.0056 17.1 0.2 0.042 14.2 0.0 2.7 2 1 0 3 3 2 1 AAA ATPase domain ANAPC3 PF12895.7 GAM38719.1 - 0.0079 16.4 0.0 36 4.7 0.0 3.9 1 1 3 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 GAM38719.1 - 0.035 14.4 3.8 2.3e+02 2.4 0.0 5.3 5 0 0 5 5 5 0 PPR repeat TPR_3 PF07720.12 GAM38719.1 - 0.042 13.8 0.0 1.1 9.3 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1897 PF09005.10 GAM38719.1 - 0.86 9.1 3.1 8.3 6.0 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1897) ComA PF02679.15 GAM38720.1 - 7e-89 297.5 0.0 8.3e-89 297.2 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) p450 PF00067.22 GAM38721.1 - 4.3e-57 193.9 0.0 5.8e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SHD1 PF03983.12 GAM38722.1 - 7.5e-35 118.6 0.0 1.3e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 GAM38722.1 - 2.3e-34 116.8 6.0 1.2e-12 47.2 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 GAM38722.1 - 1.2e-29 101.9 9.2 4.1e-12 45.8 0.5 3.8 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 GAM38722.1 - 2.6e-21 75.0 0.0 1.3e-07 31.2 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain AA_permease PF00324.21 GAM38722.1 - 2.9e-21 75.6 18.4 1.8e-14 53.2 13.3 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 GAM38722.1 - 5.3e-14 51.9 17.2 1.6e-13 50.3 17.2 1.6 1 1 0 1 1 1 1 Amino acid permease SH3_10 PF17902.1 GAM38722.1 - 0.00016 21.6 0.1 0.038 14.1 0.0 3.2 3 0 0 3 3 3 1 SH3 domain SAM_4 PF18017.1 GAM38722.1 - 0.0038 17.2 0.0 0.009 16.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Spore_permease PF03845.13 GAM38722.1 - 0.021 13.7 10.6 0.033 13.0 10.6 1.2 1 0 0 1 1 1 0 Spore germination protein SAM_1 PF00536.30 GAM38722.1 - 0.046 14.2 0.0 0.084 13.3 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 GAM38722.1 - 0.071 13.4 3.1 0.11 12.8 0.5 2.5 3 0 0 3 3 3 0 Bacterial SH3 domain PRKCSH PF07915.13 GAM38723.1 - 1e-20 74.5 1.3 3.9e-20 72.7 1.3 2.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 GAM38723.1 - 0.071 12.8 0.1 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein Pirin PF02678.16 GAM38724.1 - 4.1e-31 107.2 0.2 8.2e-31 106.2 0.1 1.6 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 GAM38724.1 - 5e-24 84.6 0.0 2.9e-23 82.2 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 GAM38724.1 - 4.8e-06 26.2 2.6 0.00011 21.8 1.0 2.3 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 GAM38724.1 - 0.016 14.9 0.0 0.61 9.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF861) PMT PF02366.18 GAM38725.1 - 2.2e-83 279.6 17.3 5.2e-83 278.4 17.3 1.7 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAM38725.1 - 1.1e-68 230.8 3.2 1.1e-68 230.8 3.2 2.9 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 GAM38725.1 - 1.4e-17 64.2 0.1 2.1e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 GAM38725.1 - 0.056 13.7 16.3 0.021 15.1 3.4 3.7 3 1 1 4 4 4 0 Dolichyl-phosphate-mannose-protein mannosyltransferase MFS_1 PF07690.16 GAM38727.1 - 2.1e-32 112.4 32.7 2.1e-32 112.4 32.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily WD40 PF00400.32 GAM38728.1 - 0.00028 21.6 7.3 5.6 8.0 0.1 5.2 6 1 0 6 6 6 3 WD domain, G-beta repeat Kri1 PF05178.12 GAM38728.1 - 0.059 13.9 2.1 2.4 8.8 0.4 2.5 2 1 0 2 2 2 0 KRI1-like family Dynein_IC2 PF11540.8 GAM38728.1 - 0.21 11.6 2.5 0.56 10.2 2.5 1.7 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 ATP-synt_E PF05680.12 GAM38729.1 - 1.2e-22 80.0 0.3 1.3e-22 79.9 0.3 1.1 1 0 0 1 1 1 1 ATP synthase E chain ABC_tran_Xtn PF12848.7 GAM38729.1 - 0.0089 16.0 0.7 0.013 15.5 0.7 1.3 1 0 0 1 1 1 1 ABC transporter CSN8_PSD8_EIF3K PF10075.9 GAM38730.1 - 5.7e-29 101.0 0.0 9.3e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 GAM38730.1 - 0.14 12.7 0.1 0.3 11.6 0.1 1.7 1 1 0 1 1 1 0 PCI domain STT3 PF02516.14 GAM38731.1 - 5.4e-149 497.2 35.8 4.1e-144 481.1 33.2 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit DUF3453 PF11935.8 GAM38732.1 - 6.6e-71 238.5 1.1 1e-70 237.9 0.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Adaptin_N PF01602.20 GAM38732.1 - 0.11 11.1 0.0 4.7 5.6 0.0 2.4 2 0 0 2 2 2 0 Adaptin N terminal region SUIM_assoc PF16619.5 GAM38732.1 - 4.5 7.4 7.8 0.23 11.5 1.5 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Sds3 PF08598.11 GAM38733.1 - 5.9e-16 59.1 0.3 5.9e-16 59.1 0.3 2.3 2 1 0 2 2 2 1 Sds3-like DUF1487 PF07368.11 GAM38733.1 - 0.1 12.1 0.3 0.25 10.8 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1487) RRM_1 PF00076.22 GAM38735.1 - 2.8e-11 43.1 0.0 4.4e-07 29.6 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CHASE4 PF05228.13 GAM38735.1 - 0.028 14.6 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 CHASE4 domain DHquinase_II PF01220.19 GAM38738.1 - 2.3 7.9 4.2 40 3.9 0.1 3.2 2 0 0 2 2 2 0 Dehydroquinase class II Methyltransf_16 PF10294.9 GAM38740.1 - 0.023 14.4 0.0 3.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Lysine methyltransferase Cys_Met_Meta_PP PF01053.20 GAM38741.1 - 9.3e-141 468.8 0.0 1.1e-140 468.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RNA_pol_Rbc25 PF08292.12 GAM38741.1 - 6.4e-33 113.7 0.0 1.2e-32 112.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 GAM38741.1 - 2.8e-14 53.2 0.0 2.3e-13 50.3 0.0 2.4 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Aminotran_1_2 PF00155.21 GAM38741.1 - 2.4e-08 33.5 0.1 4e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GAM38741.1 - 1.8e-05 23.9 1.1 2e-05 23.8 0.1 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAM38741.1 - 2.5e-05 23.8 0.6 4.4e-05 22.9 0.6 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GAM38741.1 - 0.025 13.9 0.2 0.07 12.4 0.2 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase NUFIP1 PF10453.9 GAM38742.1 - 4.7e-14 52.0 4.8 4.7e-14 52.0 4.8 2.4 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 GAM38742.1 - 3.3e-07 30.0 6.0 5.5e-07 29.3 6.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAM38742.1 - 1.5e-05 24.9 6.8 2.8e-05 24.0 6.8 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 GAM38742.1 - 2.3e-05 24.1 7.0 4.1e-05 23.3 7.0 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 GAM38742.1 - 0.23 12.2 4.0 0.27 11.9 0.0 2.6 2 0 0 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 GAM38742.1 - 0.58 10.7 4.3 0.98 10.0 4.3 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Red1 PF07964.11 GAM38742.1 - 9.3 4.3 24.5 13 3.8 24.5 1.2 1 0 0 1 1 1 0 Rec10 / Red1 GPI-anchored PF10342.9 GAM38743.1 - 1.3e-23 83.5 1.8 1.3e-23 83.5 1.8 3.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4945 PF16303.5 GAM38743.1 - 0.036 14.0 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4945) SPX PF03105.19 GAM38743.1 - 0.052 13.5 17.1 0.056 13.4 17.1 1.1 1 0 0 1 1 1 0 SPX domain Nop14 PF04147.12 GAM38743.1 - 0.15 10.2 0.3 0.18 10.0 0.3 1.0 1 0 0 1 1 1 0 Nop14-like family RIFIN PF02009.16 GAM38743.1 - 0.21 11.4 4.3 0.22 11.4 4.3 1.2 1 0 0 1 1 1 0 Rifin Apt1 PF10351.9 GAM38743.1 - 0.5 9.2 21.0 0.66 8.8 21.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 GAM38743.1 - 2.1 6.8 23.7 3.1 6.2 23.7 1.3 1 0 0 1 1 1 0 Macoilin family DUF572 PF04502.13 GAM38743.1 - 2.7 7.5 10.3 3.7 7.1 10.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Utp14 PF04615.13 GAM38743.1 - 6.1 5.3 9.5 7.3 5.0 9.5 1.0 1 0 0 1 1 1 0 Utp14 protein GREB1 PF15782.5 GAM38743.1 - 6.8 3.7 14.8 7.4 3.6 14.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer zf-C2H2 PF00096.26 GAM38744.1 - 9.5e-07 28.9 8.6 0.0048 17.3 2.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM38744.1 - 6.5e-05 23.2 0.1 6.5e-05 23.2 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAM38744.1 - 0.00053 20.6 11.2 0.0013 19.4 0.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAM38744.1 - 0.0059 16.9 0.2 0.067 13.5 0.5 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 GAM38744.1 - 0.018 15.0 0.1 0.018 15.0 0.1 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 GAM38744.1 - 0.037 14.3 0.6 0.037 14.3 0.6 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 GAM38744.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif FOXP-CC PF16159.5 GAM38744.1 - 0.81 10.4 4.0 0.64 10.7 0.2 2.6 2 2 1 3 3 3 0 FOXP coiled-coil domain APH PF01636.23 GAM38745.1 - 5.7e-08 33.0 1.8 1e-07 32.2 1.4 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM38745.1 - 0.0021 17.7 0.0 0.0035 16.9 0.0 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 GAM38745.1 - 0.11 11.4 0.2 0.14 11.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Haspin_kinase PF12330.8 GAM38745.1 - 0.19 10.6 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DUF676 PF05057.14 GAM38746.1 - 3.6e-06 26.7 0.3 1.7e-05 24.4 0.3 2.1 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 GAM38746.1 - 0.0023 17.8 0.0 0.0043 16.9 0.0 1.5 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Cutinase PF01083.22 GAM38746.1 - 0.0031 17.5 0.0 0.0045 17.0 0.0 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 GAM38746.1 - 0.0047 17.6 0.0 0.0057 17.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAM38746.1 - 0.026 14.2 0.1 0.055 13.2 0.1 1.6 1 1 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 GAM38746.1 - 0.035 14.0 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.15 GAM38746.1 - 0.11 11.7 0.1 0.23 10.6 0.1 1.5 1 1 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 GAM38746.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 ABC_tran PF00005.27 GAM38747.1 - 4.2e-51 173.1 0.1 1.7e-28 99.8 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAM38747.1 - 1.3e-28 100.5 34.3 5.4e-24 85.3 15.2 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GAM38747.1 - 1.5e-09 37.6 5.4 0.0011 18.5 0.1 4.0 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAM38747.1 - 3.3e-07 30.4 0.5 0.097 12.5 0.0 3.8 3 1 1 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM38747.1 - 6.4e-06 25.8 0.3 0.09 12.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 GAM38747.1 - 6.5e-06 25.4 0.0 0.005 15.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 GAM38747.1 - 7.4e-06 26.4 0.0 0.022 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 GAM38747.1 - 3.4e-05 23.9 0.2 0.49 10.5 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM38747.1 - 4.5e-05 23.4 0.0 0.027 14.4 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 GAM38747.1 - 5.4e-05 23.8 0.1 0.48 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 GAM38747.1 - 7e-05 22.1 0.9 0.018 14.2 0.0 2.8 2 1 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 GAM38747.1 - 0.00011 22.5 0.9 0.2 11.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 GAM38747.1 - 0.00018 22.0 0.3 0.2 12.1 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAM38747.1 - 0.0024 18.3 0.4 0.5 10.8 0.0 3.3 3 0 0 3 3 2 1 RNA helicase AAA_7 PF12775.7 GAM38747.1 - 0.0025 17.4 0.1 0.68 9.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynamin_N PF00350.23 GAM38747.1 - 0.0029 17.7 0.9 0.29 11.2 0.0 2.8 3 0 0 3 3 2 1 Dynamin family AAA_25 PF13481.6 GAM38747.1 - 0.0036 16.9 0.0 0.38 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAM38747.1 - 0.0075 16.6 0.1 2.9 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAM38747.1 - 0.0083 15.9 0.8 15 5.3 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_15 PF13175.6 GAM38747.1 - 0.01 15.6 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 GAM38747.1 - 0.013 14.8 0.1 1 8.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 GAM38747.1 - 0.014 15.1 0.1 2.3 7.9 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAM38747.1 - 0.017 15.7 0.0 3.5 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 GAM38747.1 - 0.022 15.0 0.1 32 4.8 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 GAM38747.1 - 0.023 14.6 0.0 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 GAM38747.1 - 0.029 14.5 0.4 0.91 9.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 GAM38747.1 - 0.03 13.5 0.0 8.1 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 GAM38747.1 - 0.041 13.8 1.0 4.9 7.0 0.1 2.7 2 0 0 2 2 2 0 NTPase cobW PF02492.19 GAM38747.1 - 0.052 13.1 1.1 1 8.9 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 GAM38747.1 - 0.053 13.3 0.2 0.25 11.1 0.2 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase MeaB PF03308.16 GAM38747.1 - 0.065 12.2 0.1 2.2 7.2 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 GAM38747.1 - 0.067 12.9 0.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 GAM38747.1 - 0.068 13.1 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 GAM38747.1 - 0.071 13.2 0.1 0.38 10.8 0.0 2.3 3 0 0 3 3 1 0 AAA domain Adeno_IVa2 PF02456.15 GAM38747.1 - 0.081 11.7 0.4 0.41 9.4 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF87 PF01935.17 GAM38747.1 - 0.096 12.8 1.3 0.52 10.4 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 GAM38747.1 - 0.12 12.3 0.7 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 GAM38747.1 - 0.12 12.1 0.3 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 GAM38747.1 - 0.13 12.0 1.5 6 6.5 0.7 3.0 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 GAM38747.1 - 0.17 11.6 0.1 1.5 8.5 0.0 2.4 3 1 0 3 3 2 0 AAA domain Condensation PF00668.20 GAM38748.1 - 0 1359.3 0.7 2.4e-55 188.1 0.0 12.2 11 2 0 11 11 11 10 Condensation domain AMP-binding PF00501.28 GAM38748.1 - 0 1262.4 0.0 2.3e-78 263.7 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme PP-binding PF00550.25 GAM38748.1 - 3.3e-86 283.6 7.5 5.5e-12 45.9 0.0 7.9 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAM38748.1 - 1.7e-12 48.1 0.0 0.39 11.7 0.0 6.0 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain Transferase PF02458.15 GAM38748.1 - 1.5e-06 27.1 0.1 0.11 11.1 0.0 3.7 3 0 0 3 3 3 2 Transferase family DUF5122 PF17164.4 GAM38748.1 - 0.75 10.1 8.3 35 4.8 0.1 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller LRR_4 PF12799.7 GAM38749.1 - 0.011 16.1 16.7 0.65 10.5 0.5 5.6 4 1 3 7 7 7 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM38749.1 - 0.028 14.9 2.4 40 5.3 0.0 5.1 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 GAM38749.1 - 0.5 10.2 9.1 0.072 12.9 0.5 4.0 5 1 0 5 5 5 0 Leucine rich repeat AA_permease_2 PF13520.6 GAM38750.1 - 3.1e-65 220.7 47.5 3.8e-65 220.4 47.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM38750.1 - 5.7e-22 78.0 39.5 7.3e-22 77.6 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease zf-C2H2 PF00096.26 GAM38751.1 - 0.14 12.7 22.6 0.56 10.8 1.2 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 GAM38751.1 - 3 8.5 11.1 0.36 11.5 1.0 3.3 2 1 1 3 3 3 0 FOXP coiled-coil domain Pyr_redox_2 PF07992.14 GAM38752.1 - 7.5e-08 32.0 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM38752.1 - 3.9e-05 23.7 0.0 0.00031 20.8 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 GAM38752.1 - 9.7e-05 21.7 0.0 0.00027 20.2 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAM38752.1 - 0.0086 15.4 0.0 0.38 10.0 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_1 PF00583.25 GAM38754.1 - 4.4e-11 43.0 0.1 6.2e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM38754.1 - 2.8e-09 37.3 0.2 5.4e-09 36.4 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM38754.1 - 1.2e-06 28.5 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GFO_IDH_MocA PF01408.22 GAM38755.1 - 1.1e-08 35.9 0.0 2.8e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAM38755.1 - 5e-06 26.5 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sugar_tr PF00083.24 GAM38756.1 - 3.1e-73 247.2 22.3 1.9e-72 244.6 22.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM38756.1 - 2.4e-19 69.5 29.2 2.4e-19 69.5 29.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_P35 PF03213.14 GAM38756.1 - 0.12 11.5 0.8 0.27 10.4 0.8 1.5 1 0 0 1 1 1 0 Poxvirus P35 protein OppC_N PF12911.7 GAM38756.1 - 0.44 10.5 3.0 4.1 7.4 0.6 3.0 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C MFS_1 PF07690.16 GAM38757.1 - 1.3e-23 83.6 64.1 1.6e-11 43.7 32.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 GAM38757.1 - 0.0018 17.7 21.9 0.0018 17.7 21.9 2.1 1 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Ank_2 PF12796.7 GAM38758.1 - 8.1e-50 167.4 0.3 2e-12 47.5 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 GAM38758.1 - 7.1e-40 133.7 8.0 2.2e-05 24.7 0.0 9.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 GAM38758.1 - 1.7e-36 123.8 5.8 2.1e-09 37.5 0.0 7.2 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM38758.1 - 2.1e-35 116.7 1.2 0.00027 21.2 0.0 9.8 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 GAM38758.1 - 6.6e-35 119.0 0.9 3.4e-07 30.7 0.1 6.2 2 1 4 7 7 7 7 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 GAM38758.1 - 5.2e-11 42.3 1.8 3.7e-10 39.5 0.3 2.7 2 1 0 2 2 2 1 Phosphorylase superfamily G-patch PF01585.23 GAM38758.1 - 9.4e-06 25.4 0.4 0.0026 17.6 0.1 2.8 2 0 0 2 2 2 2 G-patch domain NACHT PF05729.12 GAM38758.1 - 0.0053 16.7 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 GAM38758.1 - 0.021 15.1 0.0 0.053 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dehydratase_SU PF02287.15 GAM38760.1 - 9e-05 22.6 2.3 0.00022 21.3 0.2 2.6 3 0 0 3 3 3 1 Dehydratase small subunit USP8_interact PF08941.10 GAM38760.1 - 0.5 10.2 3.8 0.42 10.4 0.8 2.4 3 0 0 3 3 3 0 USP8 interacting Transposase_24 PF03004.14 GAM38760.1 - 0.96 9.6 6.6 0.57 10.3 0.9 2.8 2 1 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) DUF3037 PF11236.8 GAM38760.1 - 1.4 9.4 3.7 4.6 7.7 0.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3037) Dfp1_Him1_M PF08630.10 GAM38760.1 - 5 7.3 6.2 0.78 10.0 0.1 2.6 3 1 0 3 3 3 0 Dfp1/Him1, central region Troponin PF00992.20 GAM38760.1 - 9.6 6.5 10.4 0.3 11.4 3.0 2.3 3 0 0 3 3 3 0 Troponin CPSase_L_D2 PF02786.17 GAM38761.1 - 5.1e-108 359.4 0.0 1.4e-84 282.9 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 GAM38761.1 - 4.3e-41 140.1 0.0 1.3e-40 138.6 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 GAM38761.1 - 6.4e-18 65.0 0.2 1.4e-07 31.3 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAM38761.1 - 1.6e-17 63.6 0.0 9.4e-08 31.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 GAM38761.1 - 4e-10 39.6 0.0 0.0012 18.6 0.0 3.2 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 GAM38761.1 - 3.5e-06 26.6 0.0 0.017 14.6 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 GAM38761.1 - 0.00011 22.0 0.0 0.1 12.3 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 GAM38761.1 - 0.00075 19.1 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Epimerase PF01370.21 GAM38761.1 - 0.042 13.3 0.0 0.57 9.6 0.0 2.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GSH-S_ATP PF02955.16 GAM38761.1 - 0.081 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Lsr2 PF11774.8 GAM38762.1 - 0.24 11.5 2.8 0.21 11.7 0.9 1.8 2 0 0 2 2 2 0 Lsr2 Nop14 PF04147.12 GAM38762.1 - 1.1 7.3 13.9 0.037 12.2 7.2 1.7 2 0 0 2 2 2 0 Nop14-like family SET PF00856.28 GAM38764.1 - 1.1e-13 51.9 0.0 4.6e-13 49.9 0.0 2.1 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 GAM38764.1 - 2e-06 27.8 12.2 2e-06 27.8 12.2 2.9 2 1 1 3 3 3 1 MYND finger Ribosomal_S19 PF00203.21 GAM38765.1 - 1.7e-33 114.3 0.3 2.5e-33 113.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.19 GAM38766.1 - 7.6e-27 93.7 12.3 8.9e-27 93.5 12.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 GAM38766.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain Cytomega_UL84 PF06284.11 GAM38766.1 - 0.2 10.1 2.1 0.23 9.9 2.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF3824 PF12868.7 GAM38766.1 - 2 9.1 5.3 2.8 8.6 5.3 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) SPT2 PF08243.11 GAM38767.1 - 1.6e-09 38.2 17.7 4.9e-09 36.7 17.7 1.8 1 1 0 1 1 1 1 SPT2 chromatin protein Carb_kinase PF01256.17 GAM38768.1 - 3.4e-54 183.9 0.4 2.9e-53 180.8 0.4 1.9 1 1 0 1 1 1 1 Carbohydrate kinase MFS_1 PF07690.16 GAM38769.1 - 9.1e-40 136.7 44.2 9.1e-40 136.7 44.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily CoA_binding_3 PF13727.6 GAM38769.1 - 3.7 7.5 10.0 1.6 8.7 0.6 3.5 3 0 0 3 3 3 0 CoA-binding domain EIF_2_alpha PF07541.12 GAM38770.1 - 0.051 13.7 0.0 0.077 13.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit COesterase PF00135.28 GAM38771.1 - 3.5e-86 290.1 0.1 4.3e-86 289.8 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM38771.1 - 4e-08 33.4 0.1 2.9e-07 30.5 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM38771.1 - 0.091 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Nop14 PF04147.12 GAM38772.1 - 2.6e-291 969.0 28.6 2.6e-291 969.0 28.6 1.4 2 0 0 2 2 2 1 Nop14-like family HEAT_2 PF13646.6 GAM38773.1 - 0.062 13.7 0.2 0.15 12.5 0.2 1.6 1 0 0 1 1 1 0 HEAT repeats ORC3_N PF07034.11 GAM38774.1 - 1.8e-36 125.9 0.1 4.3e-34 118.1 0.0 2.6 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 GAM38774.1 - 6.7e-25 87.8 1.8 4.7e-22 78.6 0.0 2.8 2 1 0 2 2 2 1 Origin recognition complex winged helix C-terminal HisKA PF00512.25 GAM38774.1 - 6.4 6.9 5.7 6.2 6.9 0.2 3.7 5 1 0 5 5 5 0 His Kinase A (phospho-acceptor) domain PPR_2 PF13041.6 GAM38775.1 - 6.8e-05 23.0 0.0 3.3 8.0 0.0 5.0 6 0 0 6 6 6 2 PPR repeat family T3SS_needle_reg PF09025.10 GAM38775.1 - 0.0099 15.9 0.6 0.03 14.3 0.1 2.0 2 0 0 2 2 2 1 YopR, type III needle-polymerisation regulator PPR_3 PF13812.6 GAM38775.1 - 0.015 15.4 0.0 17 5.6 0.0 3.3 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR PF01535.20 GAM38775.1 - 0.13 12.6 0.4 84 3.8 0.0 4.3 4 0 0 4 4 4 0 PPR repeat Nnf1 PF03980.14 GAM38775.1 - 0.8 10.1 8.0 3.1 8.2 0.1 3.5 3 0 0 3 3 3 0 Nnf1 Sec66 PF09802.9 GAM38776.1 - 1.1e-80 269.5 0.5 1.3e-80 269.2 0.5 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 GAM38776.1 - 0.0012 18.9 0.1 0.0021 18.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3848) TPPII_N PF12583.8 GAM38776.1 - 0.28 11.8 4.3 0.56 10.8 4.3 1.5 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal AAA PF00004.29 GAM38777.1 - 1.5e-47 161.3 0.0 7.9e-42 142.8 0.0 3.4 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM38777.1 - 1e-09 38.0 0.0 3.6e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 GAM38777.1 - 1.9e-06 27.7 0.0 8e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 GAM38777.1 - 4.9e-06 26.8 0.0 1.6e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAM38777.1 - 5.2e-06 27.0 1.4 0.00021 21.7 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 GAM38777.1 - 0.00017 21.7 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 GAM38777.1 - 0.00025 21.1 0.1 0.0015 18.5 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.25 GAM38777.1 - 0.00035 20.6 0.0 0.00087 19.3 0.0 1.6 1 0 0 1 1 1 1 Bromodomain AAA_22 PF13401.6 GAM38777.1 - 0.00094 19.5 1.6 0.12 12.6 0.2 4.2 4 1 0 4 4 3 1 AAA domain AAA_14 PF13173.6 GAM38777.1 - 0.0016 18.4 0.0 0.094 12.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAM38777.1 - 0.0045 17.3 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 GAM38777.1 - 0.0053 16.4 0.0 0.026 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAM38777.1 - 0.0055 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 GAM38777.1 - 0.026 13.7 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activat PF00158.26 GAM38777.1 - 0.038 13.7 0.0 2.4 7.8 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_18 PF13238.6 GAM38777.1 - 0.04 14.4 1.3 0.14 12.7 0.0 2.6 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 GAM38777.1 - 0.043 13.2 0.1 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAM38777.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 GAM38777.1 - 0.068 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 GAM38777.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 GAM38777.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 GAM38777.1 - 0.32 10.7 0.0 0.32 10.7 0.0 3.9 3 1 0 3 3 2 0 AAA domain CPSF_A PF03178.15 GAM38778.1 - 1.2e-105 353.4 0.0 2.6e-105 352.3 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 GAM38778.1 - 4.3e-19 68.5 0.0 6.4e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.16 GAM38779.1 - 2.5e-16 59.7 25.9 5e-14 52.1 23.1 2.5 2 1 0 2 2 2 1 LMBR1-like membrane protein Anemone_cytotox PF06369.12 GAM38779.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Sea anemone cytotoxic protein DUF2964 PF11177.8 GAM38779.1 - 0.6 10.4 5.6 39 4.6 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) PBP1_TM PF14812.6 GAM38780.1 - 0.28 11.6 3.6 0.65 10.4 3.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YlbD_coat PF14071.6 GAM38781.1 - 0.028 14.7 2.5 0.038 14.3 2.5 1.2 1 0 0 1 1 1 0 Putative coat protein ACCA PF03255.14 GAM38781.1 - 0.11 12.4 1.4 0.17 11.7 0.2 1.7 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit RRF PF01765.19 GAM38782.1 - 2.3e-43 148.0 1.8 3.2e-43 147.5 1.8 1.2 1 0 0 1 1 1 1 Ribosome recycling factor HisKA_3 PF07730.13 GAM38782.1 - 0.091 13.3 3.3 1.9 9.0 0.7 3.1 2 1 1 3 3 3 0 Histidine kinase Mis12 PF05859.12 GAM38782.1 - 0.11 12.6 0.6 0.25 11.4 0.6 1.6 1 0 0 1 1 1 0 Mis12 protein WXG100 PF06013.12 GAM38782.1 - 0.84 9.9 5.8 39 4.6 3.9 3.1 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF883 PF05957.13 GAM38782.1 - 2.1 9.0 10.9 1.9 9.1 0.9 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) KfrA_N PF11740.8 GAM38782.1 - 3.9 8.2 9.7 5.6 7.7 5.0 2.8 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term Fungal_trans PF04082.18 GAM38784.1 - 1.8e-08 33.7 0.1 3.1e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM38784.1 - 7.5e-06 26.0 7.6 1.3e-05 25.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FeS_assembly_P PF01883.19 GAM38785.1 - 1.1e-08 35.1 0.0 4.2e-08 33.2 0.0 2.1 2 1 0 2 2 2 1 Iron-sulfur cluster assembly protein GTP_EFTU PF00009.27 GAM38786.1 - 4.2e-48 163.5 0.0 5.9e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 GAM38786.1 - 4.1e-36 124.2 6.3 8e-36 123.3 6.3 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 GAM38786.1 - 1.1e-23 83.4 0.0 2.4e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 GAM38786.1 - 1.5e-19 69.8 0.0 4.1e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAM38786.1 - 5.1e-09 36.4 0.0 1.4e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAM38786.1 - 2.3e-07 30.8 0.1 1.7e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 GAM38786.1 - 6.4e-07 29.4 0.1 1.2e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 GAM38786.1 - 0.0097 15.5 0.0 0.025 14.2 0.0 1.7 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 GAM38786.1 - 0.14 11.6 0.1 1.6 8.1 0.1 2.6 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Thiolase_N PF00108.23 GAM38787.1 - 2.5e-96 322.0 1.0 4.3e-96 321.3 0.3 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAM38787.1 - 1.5e-45 153.8 1.5 1.5e-45 153.8 1.5 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAM38787.1 - 4.3e-07 29.8 1.6 1.2e-06 28.3 1.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 GAM38787.1 - 0.14 12.1 1.1 11 6.0 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Zip PF02535.22 GAM38788.1 - 3.5e-50 171.1 2.6 4.7e-50 170.7 2.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter PsbH PF00737.20 GAM38788.1 - 0.4 10.4 4.8 0.32 10.7 0.9 2.7 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Atg14 PF10186.9 GAM38789.1 - 3e-77 259.8 0.2 4.2e-77 259.3 0.2 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3439 PF11921.8 GAM38789.1 - 9.8 6.2 16.3 18 5.3 10.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HSP70 PF00012.20 GAM38790.1 - 5.1e-224 744.9 8.1 5.7e-224 744.8 8.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAM38790.1 - 1e-16 60.7 0.1 9.4e-16 57.5 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GAM38790.1 - 0.00045 20.0 0.0 0.00097 18.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DevR PF01905.16 GAM38790.1 - 0.08 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 Bromodomain PF00439.25 GAM38791.1 - 4.6e-31 106.7 0.2 5.2e-18 64.9 0.1 2.4 2 0 0 2 2 2 2 Bromodomain Pox_Ag35 PF03286.14 GAM38791.1 - 9.3 6.0 10.1 0.48 10.2 4.4 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CKS PF01111.19 GAM38792.1 - 1.1e-34 118.5 1.8 1.6e-34 118.0 1.8 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Thioredoxin_4 PF13462.6 GAM38793.1 - 1.7e-12 47.8 0.0 2.3e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glycohydro_20b2 PF14845.6 GAM38793.1 - 0.0091 16.7 0.0 0.011 16.3 0.0 1.1 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like DSBA PF01323.20 GAM38793.1 - 0.057 13.2 4.7 1.2 8.8 0.2 2.8 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF3844 PF12955.7 GAM38795.1 - 2e-26 92.1 5.2 4.4e-26 91.1 5.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_alliinase PF04863.13 GAM38795.1 - 0.034 14.5 7.9 0.12 12.8 7.9 1.9 1 0 0 1 1 1 0 Alliinase EGF-like domain EGF_2 PF07974.13 GAM38795.1 - 0.035 14.5 10.0 0.085 13.2 10.0 1.7 1 1 0 1 1 1 0 EGF-like domain DUF4148 PF13663.6 GAM38795.1 - 0.066 13.4 0.7 0.2 11.9 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) zf-RING_2 PF13639.6 GAM38796.1 - 9.8e-13 48.2 6.4 1.5e-12 47.6 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM38796.1 - 7.4e-09 35.3 6.0 1.2e-08 34.7 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAM38796.1 - 2.7e-08 33.4 0.9 4.5e-08 32.7 0.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAM38796.1 - 3.5e-08 33.2 3.6 5.7e-08 32.5 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM38796.1 - 1.2e-06 28.3 3.1 1.9e-06 27.7 3.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAM38796.1 - 4.1e-06 27.0 9.8 2e-05 24.8 9.8 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAM38796.1 - 3.1e-05 23.9 0.9 3.1e-05 23.9 0.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAM38796.1 - 0.0009 19.1 2.4 0.0015 18.3 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAM38796.1 - 0.0015 18.6 2.8 0.004 17.2 2.8 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAM38796.1 - 0.011 15.4 3.1 0.018 14.7 3.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 GAM38796.1 - 0.036 13.9 6.1 0.062 13.1 6.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 GAM38796.1 - 0.052 13.4 5.4 0.11 12.5 5.4 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 GAM38796.1 - 0.065 13.4 4.6 0.13 12.4 4.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAM38796.1 - 0.092 12.6 4.9 0.2 11.5 4.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 GAM38796.1 - 0.12 12.6 3.8 0.32 11.2 3.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 GAM38796.1 - 0.18 12.0 3.8 0.37 11.0 3.8 1.6 1 1 0 1 1 1 0 RING-variant domain OAD_gamma PF04277.13 GAM38796.1 - 0.2 12.3 1.0 0.6 10.7 0.0 2.3 3 0 0 3 3 2 0 Oxaloacetate decarboxylase, gamma chain Prok-RING_1 PF14446.6 GAM38796.1 - 2 8.4 7.3 0.12 12.3 0.7 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Pro_isomerase PF00160.21 GAM38797.1 - 8.4e-52 175.6 0.9 9.5e-52 175.4 0.9 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_2c PF01411.19 GAM38798.1 - 3.5e-220 732.2 0.0 6e-220 731.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 GAM38798.1 - 2.6e-16 59.4 0.9 6.3e-16 58.2 0.9 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 GAM38798.1 - 1.7e-13 51.2 0.8 1.7e-13 51.2 0.8 2.1 2 0 0 2 2 2 1 DHHA1 domain LMSTEN PF07988.12 GAM38799.1 - 0.054 13.0 0.5 0.14 11.6 0.1 1.8 1 1 0 1 1 1 0 LMSTEN motif DUF3752 PF12572.8 GAM38800.1 - 2.7e-34 118.9 6.2 2.7e-34 118.9 6.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3752) Ada_Zn_binding PF02805.16 GAM38801.1 - 1.3e-26 92.4 4.9 2.3e-26 91.6 4.9 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 GAM38801.1 - 7.5e-07 29.1 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 GAM38801.1 - 0.00046 20.4 0.0 0.00089 19.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Flavin_Reduct PF01613.18 GAM38802.1 - 3.7e-10 40.0 0.0 5.1e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 GAM38802.1 - 0.00022 21.0 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF447) Putative_PNPOx PF01243.20 GAM38802.1 - 0.001 19.2 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Epimerase PF01370.21 GAM38803.1 - 0.0069 15.9 0.0 0.0098 15.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 GAM38803.1 - 0.0082 16.6 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 GAM38804.1 - 8e-18 64.8 0.0 1.1e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAM38804.1 - 2.5e-11 43.3 0.1 8e-10 38.3 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 GAM38804.1 - 4.8e-11 42.2 0.0 7.3e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM38804.1 - 4.2e-08 33.0 0.0 6.9e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAM38804.1 - 3.6e-06 27.0 0.0 9.1e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 GAM38804.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 GAM38804.1 - 0.0026 17.3 0.7 0.011 15.3 0.4 2.2 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.25 GAM38804.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase AMP-binding PF00501.28 GAM38805.1 - 5.4e-75 252.6 0.0 6.9e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM38805.1 - 9e-11 42.6 0.8 2e-10 41.5 0.8 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 7TM_GPCR_Srv PF10323.9 GAM38805.1 - 0.055 12.8 0.6 0.087 12.2 0.6 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv FMO-like PF00743.19 GAM38806.1 - 5.8e-19 67.9 0.0 5.6e-17 61.4 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 GAM38806.1 - 3e-10 40.2 0.0 1.2e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM38806.1 - 5.3e-08 32.5 0.0 1e-06 28.3 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM38806.1 - 1.4e-06 27.8 0.0 6.5e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM38806.1 - 4.7e-06 26.0 0.2 0.00039 19.7 0.1 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAM38806.1 - 0.00048 20.2 0.1 0.18 11.8 0.1 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 GAM38806.1 - 0.0078 15.5 0.0 0.85 8.8 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 GAM38806.1 - 0.031 13.6 0.1 0.3 10.3 0.0 2.5 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase DAO PF01266.24 GAM38806.1 - 0.13 11.8 0.2 0.7 9.4 0.0 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM38807.1 - 1.5e-08 34.2 0.0 1.5e-06 27.7 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAM38807.1 - 1.6e-05 23.6 3.1 0.00026 19.6 0.7 3.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAM38807.1 - 4.3e-05 22.8 0.0 0.00038 19.7 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAM38807.1 - 0.0018 17.6 0.0 0.023 14.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM38807.1 - 0.054 13.7 0.0 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_2 PF03446.15 GAM38807.1 - 0.058 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.14 GAM38807.1 - 0.16 10.7 0.1 3.1 6.4 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 GAM38807.1 - 0.18 12.4 0.7 0.38 11.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 GAM38808.1 - 1.4e-56 191.7 0.0 8e-56 189.2 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM38808.1 - 2.8e-44 150.9 0.1 1.1e-43 149.0 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM38808.1 - 2.9e-12 46.9 0.2 1e-11 45.1 0.1 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GAM38808.1 - 0.011 14.9 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAM38808.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 GAM38808.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.13 GAM38809.1 - 1.2e-40 139.6 0.0 1.8e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans PF04082.18 GAM38810.1 - 1.2e-24 86.8 0.1 1.7e-24 86.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM38810.1 - 0.016 15.3 5.7 0.035 14.2 5.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 GAM38811.1 - 7e-78 262.5 21.1 8.3e-78 262.2 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM38811.1 - 1.3e-19 70.4 41.7 8.6e-12 44.6 15.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 GAM38811.1 - 0.00077 18.9 21.8 0.0042 16.4 5.7 2.4 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF4811 PF16069.5 GAM38812.1 - 0.0098 15.8 0.9 4.2 7.2 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4811) Nucleoporin_C PF03177.14 GAM38813.1 - 5.7e-167 557.0 4.4 7.7e-167 556.6 4.4 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 GAM38813.1 - 8.6e-49 166.4 0.0 1.1e-48 166.1 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Acyl_transf_1 PF00698.21 GAM38814.1 - 3.4e-19 69.5 0.2 4.1e-11 42.9 0.2 2.1 1 1 1 2 2 2 2 Acyl transferase domain DUF2458 PF10454.9 GAM38814.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Sedlin_N PF04628.13 GAM38815.1 - 2.6e-11 43.8 0.0 3.3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Oxidored_q6 PF01058.22 GAM38816.1 - 3.4e-22 78.7 0.0 5.5e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit adh_short_C2 PF13561.6 GAM38817.1 - 2e-58 197.7 0.0 2.5e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM38817.1 - 1.2e-45 155.3 0.0 1.5e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM38817.1 - 1.7e-11 44.4 0.0 2.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 KR domain PALP PF00291.25 GAM38817.1 - 0.0095 15.4 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Polysacc_synt_2 PF02719.15 GAM38817.1 - 0.062 12.4 0.0 0.082 12.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 GAM38817.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Mpp10 PF04006.12 GAM38818.1 - 1.6e-109 367.1 40.3 2.3e-109 366.6 40.3 1.1 1 0 0 1 1 1 1 Mpp10 protein Methyltransf_16 PF10294.9 GAM38819.1 - 2.8e-43 147.7 0.0 3.7e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 GAM38819.1 - 0.0048 16.7 0.0 0.0071 16.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein DUF43 PF01861.16 GAM38819.1 - 0.0069 15.6 0.0 0.0095 15.2 0.0 1.1 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain MTS PF05175.14 GAM38819.1 - 0.009 15.6 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DUF1761 PF08570.10 GAM38820.1 - 2.9e-27 95.4 4.4 3.3e-27 95.2 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) AhpC-TSA PF00578.21 GAM38822.1 - 3e-22 78.9 0.0 5.3e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAM38822.1 - 1.2e-13 51.1 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 GAM38822.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.5 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme PRELI PF04707.14 GAM38823.1 - 2e-41 141.4 0.6 2.3e-41 141.2 0.6 1.0 1 0 0 1 1 1 1 PRELI-like family CTP_transf_like PF01467.26 GAM38824.1 - 5e-24 85.1 0.0 2.6e-21 76.3 0.0 3.2 3 0 0 3 3 3 2 Cytidylyltransferase-like Glutaredoxin PF00462.24 GAM38824.1 - 1e-15 57.7 0.0 6.3e-15 55.1 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin UbiA PF01040.18 GAM38825.1 - 4.6e-45 153.9 18.7 6.6e-45 153.4 18.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family JmjC PF02373.22 GAM38826.1 - 7.2e-09 36.1 1.0 1.4e-07 32.0 1.0 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 GAM38826.1 - 2.8e-07 30.7 10.5 2.8e-07 30.7 10.5 2.7 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 GAM38826.1 - 0.0029 17.3 0.0 0.0071 16.0 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Coa1 PF08695.10 GAM38827.1 - 3.7e-43 146.0 0.0 4.8e-43 145.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_L3 PF00297.22 GAM38828.1 - 2.4e-19 69.6 2.9 9.3e-16 57.8 0.8 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 DUF1279 PF06916.13 GAM38829.1 - 7.4e-25 87.3 0.1 9.2e-25 87.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ank_2 PF12796.7 GAM38830.1 - 9.4e-28 96.6 3.8 1e-11 45.3 0.0 4.8 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM38830.1 - 9.5e-23 80.3 7.7 7.5e-08 32.8 0.0 6.0 2 1 4 7 7 7 6 Ankyrin repeats (many copies) SPX PF03105.19 GAM38830.1 - 9.6e-20 71.8 12.8 1.8e-08 34.7 0.9 3.2 1 1 2 3 3 3 3 SPX domain Ank_5 PF13857.6 GAM38830.1 - 9.3e-18 64.1 5.4 0.00032 20.9 0.0 5.9 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM38830.1 - 4.5e-17 60.4 2.9 0.025 15.1 0.0 7.6 7 0 0 7 7 7 4 Ankyrin repeat GDPD PF03009.17 GAM38830.1 - 2.4e-13 50.4 0.0 7.5e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank PF00023.30 GAM38830.1 - 3.2e-08 33.7 6.5 0.38 11.3 0.1 7.3 8 1 0 8 8 8 3 Ankyrin repeat YfkB PF08756.10 GAM38830.1 - 0.018 14.9 0.1 0.95 9.2 0.0 2.4 2 0 0 2 2 2 0 YfkB-like domain SKG6 PF08693.10 GAM38831.1 - 8.2e-10 37.9 5.4 8.2e-10 37.9 5.4 2.9 2 0 0 2 2 1 1 Transmembrane alpha-helix domain RIFIN PF02009.16 GAM38831.1 - 0.0055 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Rifin DUF4448 PF14610.6 GAM38831.1 - 0.0077 16.0 0.3 0.012 15.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) PMP1_2 PF08114.11 GAM38831.1 - 0.028 14.1 2.1 0.051 13.3 2.1 1.4 1 0 0 1 1 1 0 ATPase proteolipid family TMEM154 PF15102.6 GAM38831.1 - 0.057 13.3 0.0 0.057 13.3 0.0 3.4 1 1 1 2 2 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 GAM38831.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Utp14 PF04615.13 GAM38831.1 - 0.52 8.8 5.1 0.66 8.5 5.1 1.2 1 0 0 1 1 1 0 Utp14 protein Ndc1_Nup PF09531.10 GAM38831.1 - 1.2 7.8 15.0 1.5 7.4 15.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Phage_holin_2_4 PF16082.5 GAM38831.1 - 1.6 8.5 6.3 0.13 12.0 0.4 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like PPP4R2 PF09184.11 GAM38831.1 - 2.5 7.6 12.3 3.3 7.2 12.3 1.2 1 0 0 1 1 1 0 PPP4R2 DUF4551 PF15087.6 GAM38831.1 - 6.5 5.5 11.3 7.4 5.3 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Stevor PF17410.2 GAM38831.1 - 7.5 6.0 11.2 0.2 11.2 2.6 1.9 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame SKG6 PF08693.10 GAM38832.1 - 0.011 15.1 1.5 0.019 14.4 1.5 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 GAM38832.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family YajC PF02699.15 GAM38832.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit MFS_1 PF07690.16 GAM38833.1 - 8.5e-40 136.8 38.1 1.9e-39 135.6 32.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM38833.1 - 1.3e-11 44.1 9.2 1.3e-11 44.1 9.2 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter GPR_Gpa2_C PF11970.8 GAM38833.1 - 0.93 9.6 2.8 18 5.5 0.5 3.1 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term ABC_tran PF00005.27 GAM38835.1 - 1.1e-46 158.8 0.2 3.1e-22 79.6 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 GAM38835.1 - 8.2e-21 73.8 6.6 8.2e-21 73.8 6.6 3.3 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 GAM38835.1 - 5.5e-14 52.7 12.4 0.0039 17.0 0.1 4.6 3 2 1 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM38835.1 - 7e-12 45.3 0.3 0.0042 16.5 0.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAM38835.1 - 1.3e-06 28.7 0.0 0.027 14.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAM38835.1 - 5.2e-06 26.5 0.1 0.061 13.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM38835.1 - 5.9e-06 26.3 0.2 0.08 13.0 0.1 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 GAM38835.1 - 7.2e-06 25.9 0.1 0.0029 17.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 GAM38835.1 - 1.2e-05 25.0 0.1 0.12 12.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM38835.1 - 1.6e-05 25.4 0.6 0.079 13.3 0.1 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 GAM38835.1 - 2.5e-05 24.9 13.4 0.031 14.8 0.0 4.7 5 0 0 5 5 5 2 AAA domain AAA_24 PF13479.6 GAM38835.1 - 6.7e-05 22.7 0.1 0.43 10.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GAM38835.1 - 7.2e-05 23.0 0.2 0.36 11.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 GAM38835.1 - 0.00015 22.3 3.1 0.59 10.7 0.0 3.4 5 0 0 5 5 2 2 AAA domain Dynamin_N PF00350.23 GAM38835.1 - 0.00031 20.9 0.4 2.6 8.1 0.0 3.6 3 0 0 3 3 3 1 Dynamin family AAA_28 PF13521.6 GAM38835.1 - 0.00032 21.0 2.5 0.12 12.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 GAM38835.1 - 0.0005 19.9 11.9 0.27 10.9 0.0 4.7 4 1 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 GAM38835.1 - 0.00056 20.3 0.0 0.74 10.2 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 GAM38835.1 - 0.0019 18.2 0.0 4 7.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAM38835.1 - 0.0025 17.8 0.8 0.83 9.5 0.0 2.7 3 0 0 3 3 2 1 NACHT domain RNA_helicase PF00910.22 GAM38835.1 - 0.0046 17.3 0.0 2.4 8.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_27 PF13514.6 GAM38835.1 - 0.0054 16.3 0.0 3.7 7.1 0.0 3.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAM38835.1 - 0.0073 15.6 1.0 2.8 7.2 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin MobB PF03205.14 GAM38835.1 - 0.01 15.7 0.0 0.46 10.4 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 GAM38835.1 - 0.011 14.8 4.2 1.3 7.9 0.1 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 GAM38835.1 - 0.019 14.9 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 GAM38835.1 - 0.022 14.7 0.0 8.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 GAM38835.1 - 0.03 14.2 0.2 4 7.3 0.0 3.1 3 0 0 3 3 3 0 Rad17 P-loop domain Roc PF08477.13 GAM38835.1 - 0.034 14.4 0.1 6.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 GAM38835.1 - 0.037 13.7 0.0 0.9 9.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 GAM38835.1 - 0.056 13.0 0.0 6.4 6.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 GAM38835.1 - 0.057 13.0 4.1 0.98 9.0 0.3 2.9 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 GAM38835.1 - 0.063 13.3 0.3 7.5 6.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 GAM38835.1 - 0.11 11.7 0.8 16 4.6 0.0 2.5 2 1 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 GAM38835.1 - 0.14 12.5 0.4 8.3 6.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 GAM38835.1 - 0.14 11.7 0.8 5 6.7 0.1 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 GAM38835.1 - 0.22 11.6 8.5 2.2 8.3 0.0 4.0 5 0 0 5 5 4 0 Helicase HerA, central domain AAA_17 PF13207.6 GAM38835.1 - 1.5 9.2 5.5 22 5.5 0.2 3.8 4 0 0 4 4 3 0 AAA domain Sugar_tr PF00083.24 GAM38836.1 - 5.5e-96 322.2 20.2 7.7e-96 321.7 20.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM38836.1 - 1.1e-24 87.1 35.1 4.3e-24 85.1 32.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 GAM38836.1 - 0.14 10.9 9.8 0.018 13.8 5.2 1.8 2 0 0 2 2 2 0 LacY proton/sugar symporter WD40 PF00400.32 GAM38837.1 - 1e-24 86.3 24.8 5.8e-06 26.9 0.3 6.9 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM38837.1 - 2e-10 40.8 7.5 0.0017 18.6 0.2 4.6 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 GAM38837.1 - 2.3e-06 27.7 6.9 0.017 15.0 2.1 2.4 1 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 GAM38837.1 - 0.0063 15.5 0.3 1.5 7.7 0.0 3.8 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SNF5 PF04855.12 GAM38839.1 - 5.3e-86 288.3 0.0 6.6e-86 287.9 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 GAM38839.1 - 0.00066 19.2 0.6 0.0021 17.6 0.6 1.9 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 GAM38839.1 - 0.15 11.6 0.5 3.9 7.1 1.7 2.3 1 1 1 2 2 2 0 TFIIB zinc-binding zf-CCHC_4 PF14392.6 GAM38839.1 - 0.45 10.3 3.2 0.27 11.0 0.3 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 GAM38839.1 - 0.69 9.8 5.0 0.088 12.7 0.5 1.9 2 0 0 2 2 2 0 Zinc knuckle Peptidase_M49 PF03571.15 GAM38840.1 - 2.4e-236 785.4 0.0 8.4e-236 783.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M49 Pkinase PF00069.25 GAM38840.1 - 4.2e-12 46.0 0.0 6.6e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM38840.1 - 0.0019 17.5 0.0 0.012 14.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Mito_carr PF00153.27 GAM38841.1 - 6.7e-29 99.7 1.6 4.5e-17 61.8 0.0 3.5 2 2 1 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.16 GAM38842.1 - 4.2e-43 145.4 0.5 4.9e-43 145.2 0.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit HhH-GPD PF00730.25 GAM38843.1 - 1.8e-14 54.1 0.0 5.6e-14 52.5 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein DUF4578 PF15147.6 GAM38843.1 - 0.18 12.7 2.6 0.34 11.8 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) Ecm33 PF12454.8 GAM38844.1 - 5.4e-16 58.4 3.2 1.6e-15 57.0 3.2 1.9 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 GAM38844.1 - 1.3e-09 38.1 1.3 0.14 12.2 2.5 4.6 1 1 4 5 5 5 4 Receptor L domain LRR_5 PF13306.6 GAM38844.1 - 2.9e-06 27.3 6.4 0.004 17.1 0.1 3.0 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) IMUP PF15761.5 GAM38844.1 - 0.17 12.6 6.3 0.37 11.5 6.3 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein RAP1 PF07218.11 GAM38844.1 - 4.7 5.4 4.9 6.5 4.9 4.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 GAM38844.1 - 6 6.4 8.2 9 5.8 8.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Bap31_Bap29_C PF18035.1 GAM38845.1 - 0.0036 17.3 2.4 0.0089 16.0 2.4 1.6 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Filament PF00038.21 GAM38845.1 - 0.031 13.8 0.5 0.031 13.8 0.5 1.5 2 0 0 2 2 2 0 Intermediate filament protein Terpene_synth_C PF03936.16 GAM38845.1 - 0.038 13.3 0.0 0.071 12.4 0.0 1.4 1 1 0 1 1 1 0 Terpene synthase family, metal binding domain YabA PF06156.13 GAM38845.1 - 0.098 13.3 1.8 0.79 10.4 0.0 2.2 2 0 0 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 GAM38845.1 - 0.28 11.0 2.0 0.59 9.9 2.0 1.4 1 0 0 1 1 1 0 Septum formation initiator Anp1 PF03452.14 GAM38846.1 - 4e-106 354.3 0.0 6e-106 353.7 0.0 1.3 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 GAM38846.1 - 0.0024 17.7 0.4 0.31 10.9 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 YCII PF03795.14 GAM38847.1 - 3e-10 40.4 0.0 3.8e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain ABC1 PF03109.16 GAM38848.1 - 3.9e-34 117.4 0.0 6.4e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 GAM38848.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 GAM38849.1 - 3.9e-73 246.1 0.0 1.6e-72 244.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM38849.1 - 1.5e-51 175.2 0.0 7e-51 173.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM38849.1 - 0.00024 20.0 0.0 0.00079 18.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAM38849.1 - 0.0022 17.4 0.0 0.04 13.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like GerD PF17898.1 GAM38849.1 - 0.08 12.9 1.1 0.23 11.4 1.1 1.8 1 0 0 1 1 1 0 Spore germination GerD central core domain DUF383 PF04063.14 GAM38849.1 - 0.11 12.1 2.0 0.41 10.3 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF383) DUF3385 PF11865.8 GAM38849.1 - 0.49 10.3 3.6 0.37 10.7 0.9 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) Mur_ligase_M PF08245.12 GAM38850.1 - 6.2e-08 32.9 0.1 1.6e-07 31.5 0.1 1.6 1 1 0 1 1 1 1 Mur ligase middle domain ArabFuran-catal PF09206.11 GAM38851.1 - 1.4e-152 507.5 14.3 2.2e-152 506.9 14.3 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 GAM38851.1 - 1e-57 194.1 3.6 1.8e-57 193.3 3.6 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain DAG1 PF05454.11 GAM38852.1 - 2.6 7.3 4.2 4.2 6.7 4.2 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) PRK PF00485.18 GAM38853.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 GAM38853.1 - 0.00013 22.5 0.0 0.00043 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 GAM38853.1 - 0.0012 19.2 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAM38853.1 - 0.0032 17.7 0.3 0.91 9.7 0.0 2.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAM38853.1 - 0.014 15.8 0.1 0.02 15.2 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 GAM38853.1 - 0.017 15.5 0.1 0.64 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAM38853.1 - 0.019 15.2 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GAM38853.1 - 0.032 13.4 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 GAM38853.1 - 0.04 13.2 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 GAM38853.1 - 0.04 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 GAM38853.1 - 0.041 14.1 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 GAM38853.1 - 0.066 12.9 0.0 2.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.12 GAM38853.1 - 0.087 12.1 0.2 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin RuvB_N PF05496.12 GAM38853.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain dNK PF01712.19 GAM38853.1 - 0.16 11.8 0.0 0.45 10.3 0.0 1.8 1 1 0 1 1 1 0 Deoxynucleoside kinase Viral_helicase1 PF01443.18 GAM38853.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 GAM38853.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ribonuc_red_lgC PF02867.15 GAM38854.1 - 1.2e-186 621.3 0.0 1.9e-186 620.7 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 GAM38854.1 - 1.2e-25 89.3 0.1 2.9e-25 88.1 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 GAM38854.1 - 6e-17 62.0 0.0 1.5e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain FAD_binding_3 PF01494.19 GAM38855.1 - 2.3e-25 89.6 0.0 5.4e-24 85.1 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM38855.1 - 1.4e-07 31.1 0.4 0.00064 19.0 0.1 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM38855.1 - 0.00012 21.3 1.4 0.023 13.8 0.5 2.9 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAM38855.1 - 0.00024 21.3 0.2 0.0006 20.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM38855.1 - 0.00064 18.9 0.6 0.0018 17.4 0.1 1.9 3 0 0 3 3 3 1 FAD binding domain SE PF08491.10 GAM38855.1 - 0.0034 16.5 0.0 0.023 13.7 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 GAM38855.1 - 0.007 16.9 0.4 2.6 8.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM38855.1 - 0.0077 15.8 2.0 0.032 13.8 0.5 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM38855.1 - 0.049 13.6 0.3 5.2 7.0 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 GAM38855.1 - 0.061 12.2 0.1 8.1 5.2 0.0 2.9 3 0 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.22 GAM38855.1 - 0.15 11.1 0.1 0.3 10.1 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A DPBB_1 PF03330.18 GAM38857.1 - 6.8e-06 26.3 0.1 2.3e-05 24.6 0.1 2.0 1 1 0 1 1 1 1 Lytic transglycolase DUF4772 PF15997.5 GAM38857.1 - 0.13 12.9 0.1 0.22 12.1 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4772) zf-HC3 PF16827.5 GAM38857.1 - 1.2 9.4 3.6 0.54 10.5 0.3 2.1 2 0 0 2 2 2 0 zinc-finger Ndc1_Nup PF09531.10 GAM38857.1 - 4.2 5.9 5.7 5 5.7 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF5525 PF17663.1 GAM38857.1 - 7.5 4.5 23.2 8.6 4.3 23.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5525) MFS_1 PF07690.16 GAM38858.1 - 3.1e-08 33.0 39.9 3.1e-08 33.0 39.9 4.1 2 2 1 3 3 3 2 Major Facilitator Superfamily DUF3995 PF13160.6 GAM38858.1 - 7 7.0 25.0 0.038 14.3 1.7 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF3995) ELFV_dehydrog PF00208.21 GAM38860.1 - 2.7e-82 276.1 1.6 3.4e-82 275.8 1.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 GAM38860.1 - 1.8e-51 173.4 0.0 3e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain FMO-like PF00743.19 GAM38860.1 - 0.011 14.2 0.0 0.016 13.6 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 GAM38860.1 - 0.019 15.0 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Qn_am_d_aIV PF09100.10 GAM38860.1 - 0.04 13.8 0.3 0.091 12.6 0.1 1.7 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV NAD_binding_7 PF13241.6 GAM38860.1 - 0.087 13.3 0.3 0.25 11.8 0.2 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding Aldo_ket_red PF00248.21 GAM38861.1 - 2.6e-40 138.4 0.0 4.7e-38 131.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Med5 PF08689.10 GAM38863.1 - 1.8e-160 536.1 0.0 2.1e-159 532.5 0.0 2.2 1 1 0 1 1 1 1 Mediator complex subunit Med5 BRX_N PF13713.6 GAM38863.1 - 0.028 14.2 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain RasGEF PF00617.19 GAM38864.1 - 6e-51 173.1 0.4 1e-50 172.4 0.4 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM38864.1 - 1.8e-14 53.8 0.0 4e-13 49.5 0.0 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.6 GAM38864.1 - 4.3e-06 26.5 0.0 1.3e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 GAM38864.1 - 3.5e-05 23.3 0.0 0.00011 21.8 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAM38864.1 - 0.0072 16.0 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain HATPase_c_3 PF13589.6 GAM38866.1 - 1.8e-17 63.5 0.0 6.8e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 GAM38866.1 - 2.9e-07 30.4 0.0 3e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 GAM38866.1 - 0.1 13.1 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Caleosin PF05042.13 GAM38867.1 - 1.3e-77 259.5 0.2 1.7e-77 259.2 0.2 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_1 PF00036.32 GAM38867.1 - 3.5e-05 23.0 1.2 0.0003 20.1 0.2 2.8 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 GAM38867.1 - 6.7e-05 22.5 1.6 0.0035 17.2 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 GAM38867.1 - 0.0016 18.9 1.0 0.017 15.5 0.3 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 GAM38867.1 - 0.0081 16.0 0.4 0.039 13.8 0.0 2.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 GAM38867.1 - 0.0093 15.4 4.4 0.05 13.1 0.2 3.3 3 0 0 3 3 3 1 EF hand Pro_CA PF00484.19 GAM38868.1 - 1.8e-07 31.6 0.0 2.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase GTP_EFTU PF00009.27 GAM38868.1 - 0.078 12.5 0.8 0.097 12.2 0.8 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain bZIP_2 PF07716.15 GAM38870.1 - 1.6e-12 47.3 14.5 3e-12 46.4 14.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAM38870.1 - 0.0013 18.7 11.1 0.0028 17.7 11.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 GAM38870.1 - 0.097 13.0 0.5 0.24 11.8 0.5 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family CENP-N PF05238.13 GAM38871.1 - 8.3e-127 423.9 0.3 3.7e-126 421.8 0.0 2.0 2 0 0 2 2 2 1 Kinetochore protein CHL4 like DUF974 PF06159.13 GAM38871.1 - 3.6e-78 262.8 0.0 6.3e-78 262.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF974) zf-RING_2 PF13639.6 GAM38871.1 - 2.7e-07 30.8 6.2 2.7e-07 30.8 6.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 GAM38871.1 - 0.0002 21.4 2.2 0.0002 21.4 2.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 GAM38871.1 - 0.0028 17.6 2.4 0.0086 16.0 2.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 FANCL_C PF11793.8 GAM38871.1 - 0.0073 16.5 2.9 0.018 15.2 2.9 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain SWIM PF04434.17 GAM38871.1 - 0.0086 15.7 0.3 0.018 14.7 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_4 PF14570.6 GAM38871.1 - 0.05 13.4 6.4 0.096 12.5 6.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 GAM38871.1 - 0.13 12.4 7.6 0.27 11.4 7.6 1.5 1 0 0 1 1 1 0 RING-variant domain zf-rbx1 PF12678.7 GAM38871.1 - 0.46 10.8 4.4 1.2 9.5 4.4 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAM38871.1 - 0.63 10.1 6.0 1.8 8.7 6.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.11 GAM38871.1 - 0.99 9.8 3.0 2.7 8.4 3.0 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 GAM38871.1 - 1 9.3 5.8 2.7 7.9 5.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 GAM38871.1 - 9.6 6.2 10.8 1.7 8.6 6.9 1.9 2 0 0 2 2 1 0 PHD-finger DoxX_2 PF13564.6 GAM38872.1 - 0.0076 16.3 0.7 0.0093 16.1 0.7 1.4 1 1 0 1 1 1 1 DoxX-like family DENN PF02141.21 GAM38873.1 - 2.8e-57 193.7 0.0 6.5e-57 192.5 0.0 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 GAM38873.1 - 8.1e-15 55.3 0.0 2.1e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 GAM38873.1 - 8.7e-14 51.3 0.3 2.5e-13 49.8 0.3 1.9 1 0 0 1 1 1 1 dDENN domain C1_2 PF03107.16 GAM38873.1 - 4.9e-06 26.8 3.6 9.4e-06 25.8 3.6 1.5 1 0 0 1 1 1 1 C1 domain PHD PF00628.29 GAM38873.1 - 0.054 13.4 9.3 0.038 13.9 6.9 2.0 1 1 1 2 2 2 0 PHD-finger C1_1 PF00130.22 GAM38873.1 - 0.25 11.3 9.8 0.46 10.4 9.8 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 GAM38873.1 - 2.2 8.4 6.9 7.2 6.8 7.1 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger zf-HIT PF04438.16 GAM38873.1 - 4.8 7.1 7.4 12 5.9 7.5 1.6 1 1 0 1 1 1 0 HIT zinc finger DHquinase_I PF01487.15 GAM38874.1 - 5.9e-44 151.0 0.0 8.8e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.18 GAM38875.1 - 7.1e-21 74.4 0.4 7.1e-21 74.4 0.4 2.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain Cyt-b5 PF00173.28 GAM38876.1 - 1.8e-09 37.6 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.22 GAM38877.1 - 1.4e-60 201.0 0.1 9.2e-19 67.0 0.1 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 GAM38877.1 - 0.0012 18.7 0.0 0.8 9.5 0.0 2.9 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 GAM38877.1 - 0.0026 17.8 0.0 4.6 7.4 0.0 3.7 3 1 0 3 3 3 1 RNA recognition motif DbpA PF03880.15 GAM38877.1 - 0.0048 16.9 0.1 1.4 9.0 0.0 2.8 2 0 0 2 2 2 1 DbpA RNA binding domain TFIIA PF03153.13 GAM38877.1 - 0.0048 16.9 11.3 0.0048 16.9 11.3 2.7 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit RRM_5 PF13893.6 GAM38877.1 - 0.02 14.5 0.0 2.7 7.6 0.0 2.4 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 GAM38877.1 - 0.024 14.7 0.4 0.44 10.7 0.1 3.0 3 0 0 3 3 3 0 Limkain b1 SET_assoc PF11767.8 GAM38877.1 - 0.048 13.3 0.0 3.7 7.3 0.0 3.2 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated BRAP2 PF07576.12 GAM38877.1 - 0.058 13.6 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 BRCA1-associated protein 2 Rad10 PF03834.14 GAM38878.1 - 1.5e-47 160.3 0.1 2.2e-47 159.8 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 GAM38878.1 - 2.8e-05 24.6 0.1 0.00027 21.5 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 GAM38878.1 - 0.0026 17.5 0.0 0.0062 16.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 GAM38878.1 - 0.0062 16.6 0.1 0.033 14.3 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif PTPRCAP PF15713.5 GAM38878.1 - 0.1 12.9 2.6 0.19 12.0 2.6 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated ABC_membrane PF00664.23 GAM38880.1 - 9.8e-35 120.5 26.5 4.5e-28 98.7 18.5 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM38880.1 - 1e-28 100.6 3.4 2.2e-18 67.1 0.1 3.5 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAM38880.1 - 1.6e-07 31.0 0.7 0.0032 16.9 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAM38880.1 - 2.9e-05 24.0 1.9 0.31 10.8 0.1 3.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM38880.1 - 0.00063 19.4 0.2 0.0017 18.0 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.22 GAM38880.1 - 0.0011 18.2 0.0 0.0026 17.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain T2SSE PF00437.20 GAM38880.1 - 0.011 14.8 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 GAM38880.1 - 0.048 13.6 0.5 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase SbcCD_C PF13558.6 GAM38880.1 - 0.053 13.8 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 GAM38880.1 - 0.055 13.0 1.7 0.2 11.2 0.3 2.5 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GAM38880.1 - 0.06 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAM38880.1 - 0.1 12.3 0.7 8.1 6.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 GAM38880.1 - 0.16 11.6 0.6 0.33 10.5 0.6 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 GAM38880.1 - 0.18 12.2 1.3 0.44 10.9 0.5 2.1 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 GAM38880.1 - 0.19 11.8 0.7 0.58 10.2 0.1 2.2 3 0 0 3 3 1 0 Dynamin family AAA_22 PF13401.6 GAM38880.1 - 0.22 11.8 2.0 2.1 8.6 0.5 2.7 2 1 0 2 2 2 0 AAA domain DUF2207 PF09972.9 GAM38880.1 - 0.37 9.5 1.2 1.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Renin_r PF07850.14 GAM38880.1 - 0.92 10.2 4.0 1.2 9.8 0.3 2.7 3 0 0 3 3 2 0 Renin receptor-like protein MFS_1 PF07690.16 GAM38881.1 - 8.4e-08 31.5 8.2 5.8e-07 28.8 7.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily HPIP_like PF18524.1 GAM38881.1 - 9.7e-05 22.1 1.2 12 5.7 0.0 5.1 1 1 4 5 5 5 3 High potential iron-sulfur protein like DDE_Tnp_1_assoc PF13808.6 GAM38881.1 - 0.042 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-associated DUF3328 PF11807.8 GAM38882.1 - 0.0013 18.5 0.1 0.0013 18.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Dala_Dala_lig_C PF07478.13 GAM38883.1 - 2.7e-10 40.1 0.0 5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Methyltransf_25 PF13649.6 GAM38883.1 - 1.3e-09 38.6 0.0 2.8e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM38883.1 - 2.4e-09 37.2 0.0 1.1e-08 35.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM38883.1 - 1e-05 25.5 0.0 2.9e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM38883.1 - 1.1e-05 26.1 0.0 3.8e-05 24.3 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM38883.1 - 1.4e-05 25.7 0.0 2.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM38883.1 - 6.1e-05 22.6 0.2 0.001 18.6 0.1 2.3 1 1 1 2 2 2 1 Methyltransferase small domain ATP-grasp_3 PF02655.14 GAM38883.1 - 0.0033 17.5 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ubie_methyltran PF01209.18 GAM38883.1 - 0.039 13.3 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 GAM38883.1 - 0.043 13.8 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 GAM38883.1 - 0.11 11.8 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aminotran_1_2 PF00155.21 GAM38884.1 - 1.8e-57 195.2 0.0 2.1e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAM38884.1 - 1.2e-07 30.6 0.0 2e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 GAM38884.1 - 7.3e-07 28.7 0.1 1e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 GAM38884.1 - 0.00011 21.3 0.2 0.00027 20.0 0.0 1.7 2 1 1 3 3 3 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAM38884.1 - 0.0005 19.5 0.2 0.00078 18.8 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Methyltransf_31 PF13847.6 GAM38884.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TRAM_LAG1_CLN8 PF03798.16 GAM38885.1 - 2.9e-40 138.1 25.5 1.6e-39 135.7 22.3 2.0 2 0 0 2 2 2 2 TLC domain TRAM1 PF08390.11 GAM38885.1 - 1.5e-16 59.7 0.2 4.4e-16 58.3 0.2 1.8 1 0 0 1 1 1 1 TRAM1-like protein Chorion_2 PF03964.15 GAM38885.1 - 4.1 8.3 5.8 1.8 9.4 2.5 2.1 2 0 0 2 2 2 0 Chorion family 2 DUF997 PF06196.12 GAM38887.1 - 0.011 15.7 0.1 0.011 15.7 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF997) 4F5 PF04419.14 GAM38888.1 - 1e-10 42.3 9.1 1e-10 42.3 9.1 2.0 1 1 1 2 2 2 1 4F5 protein family Cu_bind_like PF02298.17 GAM38889.1 - 0.0088 16.0 0.6 0.042 13.9 0.6 2.0 1 1 0 1 1 1 1 Plastocyanin-like domain SMN PF06003.12 GAM38890.1 - 3.3e-09 36.4 0.3 7.3e-05 22.2 0.1 2.2 2 0 0 2 2 2 2 Survival motor neuron protein (SMN) RRM_1 PF00076.22 GAM38891.1 - 6.2e-15 54.8 0.0 1.6e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM38891.1 - 0.017 15.1 0.1 0.041 13.9 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 GAM38891.1 - 0.044 13.4 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CHD5 PF04420.14 GAM38892.1 - 8.4e-46 155.7 8.8 4.9e-24 85.0 0.5 2.2 1 1 1 2 2 2 2 CHD5-like protein CcmD PF04995.14 GAM38892.1 - 0.047 13.8 0.1 0.047 13.8 0.1 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Thiolase_N PF00108.23 GAM38893.1 - 2.3e-17 63.2 0.0 7.7e-17 61.5 0.0 1.9 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAM38893.1 - 1.4e-11 44.1 1.4 2.5e-10 40.1 1.6 2.4 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 GAM38893.1 - 1.3e-05 25.0 0.1 0.00098 18.9 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 GAM38893.1 - 0.019 13.7 0.3 0.056 12.1 0.1 1.8 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) BRO1 PF03097.18 GAM38894.1 - 2.2e-125 418.5 0.1 4.4e-125 417.5 0.1 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 GAM38894.1 - 1.1e-86 290.8 12.5 1.1e-86 290.8 12.5 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Mito_carr PF00153.27 GAM38894.1 - 2.1e-35 120.5 5.2 4.1e-15 55.5 0.1 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein TPR_MLP1_2 PF07926.12 GAM38894.1 - 0.4 10.7 10.0 0.29 11.2 6.5 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fungal_trans PF04082.18 GAM38895.1 - 1.2e-15 57.3 0.0 2.4e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_8 PF13450.6 GAM38895.1 - 1.8e-08 34.5 0.1 8e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 GAM38895.1 - 6.4e-08 31.5 0.1 9e-07 27.7 0.1 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAM38895.1 - 7.1e-07 28.8 0.1 0.0036 16.6 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM38895.1 - 1.1e-06 28.1 0.4 0.001 18.3 0.2 3.7 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 GAM38895.1 - 0.0005 19.4 0.0 0.0036 16.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM38895.1 - 0.0013 18.1 0.2 0.2 10.9 0.0 2.6 3 0 0 3 3 3 1 Thi4 family Tmemb_cc2 PF10267.9 GAM38895.1 - 0.029 13.5 0.2 0.045 12.9 0.2 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein NPV_P10 PF05531.12 GAM38895.1 - 0.075 13.5 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MSA-2c PF12238.8 GAM38895.1 - 0.099 12.6 0.7 0.88 9.5 1.5 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c NAD_binding_9 PF13454.6 GAM38895.1 - 0.14 12.1 0.0 0.64 10.0 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding CK_II_beta PF01214.18 GAM38896.1 - 2.3e-77 258.9 0.0 5.9e-77 257.6 0.0 1.7 1 1 0 1 1 1 1 Casein kinase II regulatory subunit p450 PF00067.22 GAM38896.1 - 3.1e-32 111.9 0.1 4.2e-12 45.6 0.0 3.2 1 1 2 3 3 3 3 Cytochrome P450 DUF4637 PF15470.6 GAM38896.1 - 0.36 10.5 2.8 0.87 9.3 2.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Spt5_N PF11942.8 GAM38896.1 - 0.49 11.4 9.5 0.31 12.1 6.6 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal NOA36 PF06524.12 GAM38896.1 - 8.5 5.6 6.0 17 4.6 6.0 1.4 1 0 0 1 1 1 0 NOA36 protein p450 PF00067.22 GAM38897.1 - 1.1e-79 268.4 0.0 1.5e-79 268.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.25 GAM38897.1 - 1.9e-19 70.3 0.0 4.3e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAM38897.1 - 5.7e-11 43.0 0.0 1.3e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 GAM38897.1 - 6.2e-08 32.5 0.0 1.4e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_5 PF12724.7 GAM38897.1 - 0.024 14.9 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain bZIP_2 PF07716.15 GAM38898.1 - 0.00065 19.7 4.7 0.0012 18.8 4.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAM38898.1 - 0.0013 18.8 7.0 0.0013 18.8 7.0 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 GAM38898.1 - 0.45 11.1 8.2 0.64 10.6 7.4 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor Aminotran_4 PF01063.19 GAM38899.1 - 2.6e-34 119.0 0.0 3.6e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV G-patch PF01585.23 GAM38900.1 - 1.9e-09 37.3 2.6 3.9e-09 36.2 2.6 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 GAM38900.1 - 9.8e-05 22.1 0.0 0.0025 17.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.26 GAM38901.1 - 1.2e-48 164.4 0.0 1.3e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM38901.1 - 5.2e-06 26.2 0.0 4.4e-05 23.2 0.0 1.9 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 GAM38901.1 - 0.013 15.7 1.3 0.052 13.8 1.3 1.9 1 1 0 1 1 1 0 RWD domain Ank_4 PF13637.6 GAM38902.1 - 8.9e-06 26.2 0.0 1.7e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM38902.1 - 0.0041 17.7 0.0 0.0073 16.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM38902.1 - 0.028 14.9 0.0 4.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat MutL_C PF08676.11 GAM38902.1 - 0.053 13.3 0.6 2.9 7.7 0.1 2.6 2 1 0 2 2 2 0 MutL C terminal dimerisation domain VPS9 PF02204.18 GAM38902.1 - 0.1 12.8 0.1 0.74 10.1 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain Asn_synthase PF00733.21 GAM38903.1 - 3.7e-92 309.7 0.1 2.6e-54 185.2 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 GAM38903.1 - 4.2e-36 123.6 0.0 6.9e-36 122.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAM38903.1 - 2.3e-26 92.6 0.0 4e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 GAM38903.1 - 3.6e-07 29.9 0.0 6.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 GAM38903.1 - 0.0022 17.2 0.0 0.0046 16.1 0.0 1.4 1 1 0 1 1 1 1 NAD synthase QueC PF06508.13 GAM38903.1 - 0.084 12.4 0.1 0.36 10.3 0.1 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Porin_3 PF01459.22 GAM38904.1 - 2.7e-77 259.9 3.0 3e-77 259.7 3.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin DnaJ PF00226.31 GAM38905.1 - 4.6e-23 81.1 0.9 7.9e-23 80.4 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain Peptidase_M24 PF00557.24 GAM38906.1 - 2.3e-42 145.1 0.1 3.2e-42 144.6 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 FA_desaturase PF00487.24 GAM38906.1 - 9e-28 97.8 10.2 1.7e-27 96.9 10.2 1.5 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 GAM38906.1 - 5.2e-18 64.2 1.8 1.6e-17 62.7 0.3 2.5 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) Drc1-Sld2 PF11719.8 GAM38906.1 - 0.18 11.3 9.7 0.3 10.6 9.7 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein YL1 PF05764.13 GAM38906.1 - 0.35 10.9 10.6 0.7 10.0 10.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CCDC106 PF15794.5 GAM38906.1 - 5.5 6.6 7.1 8.7 6.0 7.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Motile_Sperm PF00635.26 GAM38907.1 - 5e-24 84.3 0.0 1.4e-23 82.8 0.0 1.7 1 1 1 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 GAM38907.1 - 0.0094 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixG_C PF11614.8 GAM38907.1 - 0.03 14.5 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase UBA PF00627.31 GAM38908.1 - 1.2e-07 31.5 0.1 3.4e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.20 GAM38908.1 - 1.2e-05 25.4 0.3 4.9e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 UBX domain zf-C2H2 PF00096.26 GAM38908.1 - 0.18 12.4 0.2 0.33 11.5 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 GAM38908.1 - 0.39 11.1 4.2 0.12 12.7 0.6 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) SOBP PF15279.6 GAM38908.1 - 1.8 9.1 11.7 2.2 8.8 11.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein OrsD PF12013.8 GAM38908.1 - 2.2 8.7 6.7 6.3 7.3 0.2 2.7 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D V_ATPase_I PF01496.19 GAM38908.1 - 2.9 5.7 9.0 3.4 5.5 9.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 GAM38908.1 - 9.4 5.0 9.0 12 4.7 9.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Rad52_Rad22 PF04098.15 GAM38909.1 - 4.1e-58 195.7 0.0 5.7e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Aa_trans PF01490.18 GAM38910.1 - 1.1e-66 225.3 33.0 1.6e-49 168.8 19.3 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein TatD_DNase PF01026.21 GAM38911.1 - 3.4e-52 177.4 0.0 4e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase FMN_dh PF01070.18 GAM38912.1 - 3.1e-87 292.9 0.2 2.1e-79 267.1 0.0 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 GAM38912.1 - 4.6e-18 65.1 0.0 8.8e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ThiG PF05690.14 GAM38912.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG SAP PF02037.27 GAM38913.1 - 9.9e-10 38.0 0.1 1.7e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 SAP domain S-AdoMet_synt_C PF02773.16 GAM38913.1 - 0.15 12.1 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, C-terminal domain Syntaxin_2 PF14523.6 GAM38914.1 - 1.6e-26 92.6 3.6 1.6e-26 92.6 3.6 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 GAM38914.1 - 5.3e-16 58.4 2.3 5.9e-16 58.2 0.7 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 GAM38914.1 - 1.8e-07 31.0 11.7 3.5e-07 30.1 11.7 1.5 1 1 0 1 1 1 1 Syntaxin DUF883 PF05957.13 GAM38914.1 - 0.024 15.2 9.8 0.033 14.8 0.1 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Synaptobrevin PF00957.21 GAM38914.1 - 0.025 14.3 1.2 0.084 12.7 0.3 2.3 2 0 0 2 2 2 0 Synaptobrevin Nre_C PF04895.12 GAM38914.1 - 0.026 14.4 1.9 0.045 13.7 0.1 2.2 2 0 0 2 2 2 0 Archaeal Nre, C-terminal Type_III_YscX PF09474.10 GAM38914.1 - 0.24 11.7 4.5 4.5 7.6 0.1 2.7 2 1 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) DUF1664 PF07889.12 GAM38914.1 - 1.9 8.6 6.2 14 5.7 0.3 2.7 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) Ndc1_Nup PF09531.10 GAM38915.1 - 5.4e-163 543.9 0.1 6.1e-163 543.8 0.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup FMN_dh PF01070.18 GAM38916.1 - 1.2e-109 366.5 0.0 1.4e-109 366.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 GAM38916.1 - 0.00021 20.4 1.0 0.00042 19.4 1.0 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 GAM38916.1 - 0.0036 16.5 0.1 0.0054 15.9 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 GAM38916.1 - 0.015 14.7 0.7 0.65 9.4 0.0 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 GAM38916.1 - 0.026 13.8 0.9 1.7 7.9 0.1 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Vfa1 PF08432.10 GAM38917.1 - 4.1e-32 112.0 26.7 7.8e-32 111.1 26.7 1.5 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 4HBT PF03061.22 GAM38917.1 - 0.0073 16.6 0.1 1.2 9.5 0.0 2.3 2 0 0 2 2 2 1 Thioesterase superfamily DUF262 PF03235.14 GAM38917.1 - 2.4 8.3 11.5 4.7 7.3 11.5 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF262 CDC27 PF09507.10 GAM38917.1 - 2.4 7.4 31.6 4.4 6.6 31.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DDHD PF02862.17 GAM38917.1 - 2.6 8.2 8.0 5.7 7.0 8.0 1.5 1 0 0 1 1 1 0 DDHD domain PIEZO PF15917.5 GAM38917.1 - 3.8 6.9 17.1 8.7 5.8 17.1 1.5 1 0 0 1 1 1 0 Piezo CDC45 PF02724.14 GAM38917.1 - 4.7 5.4 21.0 6.8 4.9 21.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 GAM38917.1 - 6.8 5.9 11.7 13 5.0 11.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPR3 PF03666.13 GAM38917.1 - 6.9 5.3 18.3 11 4.7 18.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA_11 PF13086.6 GAM38917.1 - 6.9 6.4 11.9 15 5.3 11.9 1.6 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.16 GAM38917.1 - 8 6.4 7.7 8.2 6.4 5.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region zf-C2H2 PF00096.26 GAM38919.1 - 0.021 15.3 1.7 0.021 15.3 1.7 5.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-FCS PF06467.14 GAM38919.1 - 0.031 14.2 3.2 3.9 7.5 0.2 2.9 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-CHCC PF10276.9 GAM38919.1 - 0.083 13.0 5.3 3.6 7.7 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_jaz PF12171.8 GAM38919.1 - 2.8 8.3 14.5 0.43 10.9 3.7 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Asp PF00026.23 GAM38920.1 - 6.7e-71 239.3 7.6 9.6e-71 238.8 7.6 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM38920.1 - 1.5e-07 31.9 11.1 6.1e-07 29.8 4.3 2.9 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAM38920.1 - 6.8e-05 23.4 0.6 0.59 10.8 0.0 3.0 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 GAM38920.1 - 0.039 13.7 4.2 0.059 13.1 0.1 2.6 2 1 1 3 3 3 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 GAM38920.1 - 0.04 14.5 0.1 6.6 7.4 0.0 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Period_C PF12114.8 GAM38920.1 - 1 8.9 5.6 2.4 7.7 5.6 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region RCC1 PF00415.18 GAM38922.1 - 1.5e-55 185.6 12.5 4.5e-11 43.2 0.0 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM38922.1 - 5.1e-35 118.6 29.1 3.4e-07 29.9 0.1 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 GAM38922.1 - 0.19 11.4 0.0 37 4.0 0.0 4.0 5 0 0 5 5 5 0 TUP1-like enhancer of split Cyto_heme_lyase PF01265.17 GAM38923.1 - 4.2e-38 131.6 0.9 1.2e-32 113.7 0.0 3.0 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase AKAP2_C PF15304.6 GAM38923.1 - 0.038 13.3 1.2 0.048 13.0 1.2 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus ATP13 PF12921.7 GAM38923.1 - 0.085 12.7 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ATPase expression MDD_C PF18376.1 GAM38924.1 - 5.1e-62 208.9 0.0 8.7e-62 208.2 0.0 1.4 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 GAM38924.1 - 4.7e-09 36.4 0.3 1.7e-08 34.5 0.5 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain IKI3 PF04762.12 GAM38925.1 - 0 1025.0 0.0 0 1024.7 0.0 1.0 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 GAM38925.1 - 0.0064 16.8 0.1 10 6.5 0.0 4.3 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 GAM38925.1 - 0.68 9.9 4.5 0.94 9.4 1.7 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM38925.1 - 6.5 7.9 6.0 3.9 8.5 0.4 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat COX7C PF02935.16 GAM38926.1 - 1.4e-18 66.9 5.2 2.2e-18 66.3 5.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.6 GAM38927.1 - 1.1e-91 307.5 1.8 1.3e-91 307.2 0.2 1.9 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 GAM38927.1 - 7e-57 191.6 3.2 1e-56 191.1 2.0 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 GAM38927.1 - 2.5e-18 66.5 0.4 7.8e-18 64.9 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM38927.1 - 4.3e-07 30.3 0.0 1.4e-06 28.6 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM38927.1 - 2.6e-05 24.3 0.0 6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 GAM38927.1 - 0.0031 16.6 0.1 0.013 14.6 0.0 2.1 3 0 0 3 3 3 1 Type II/IV secretion system protein ATPase_2 PF01637.18 GAM38927.1 - 0.035 14.0 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 GAM38927.1 - 0.13 12.6 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF5388 PF17363.2 GAM38927.1 - 0.36 11.1 3.7 0.44 10.8 0.3 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5388) Cytochrom_B562 PF07361.11 GAM38927.1 - 9.9 6.9 7.0 16 6.2 0.6 3.7 5 0 0 5 5 5 0 Cytochrome b562 Cut8 PF08559.10 GAM38928.1 - 1.5e-80 270.3 0.0 1.7e-80 270.1 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Methyltransf_23 PF13489.6 GAM38929.1 - 7.6e-22 77.9 0.0 1.2e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM38929.1 - 3.6e-08 34.0 0.0 1.5e-07 32.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM38929.1 - 1e-05 26.2 0.0 0.00062 20.5 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM38929.1 - 1.7e-05 25.4 0.0 6.9e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM38929.1 - 0.0013 18.6 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAM38929.1 - 0.0089 15.6 0.0 0.045 13.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 GAM38929.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase OTCace_N PF02729.21 GAM38930.1 - 9.8e-47 158.7 0.0 1.5e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 GAM38930.1 - 5.9e-45 153.2 0.0 9.2e-45 152.5 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Bac_rhamnosid PF05592.11 GAM38930.1 - 0.037 14.0 0.0 0.1 12.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain GHL15 PF14885.6 GAM38930.1 - 0.2 11.6 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 Glyco_hydro_101 PF12905.7 GAM38930.1 - 0.21 10.9 0.0 0.32 10.4 0.0 1.1 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase DUF3712 PF12505.8 GAM38931.1 - 8.9e-09 35.7 0.1 3.8e-06 27.2 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 GAM38931.1 - 0.00036 21.0 0.5 0.053 14.1 0.0 4.2 4 0 0 4 4 4 1 Late embryogenesis abundant protein ALS_ss_C PF10369.9 GAM38932.1 - 1e-15 57.6 0.0 4.1e-14 52.5 0.0 2.5 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 GAM38932.1 - 5.6e-12 45.2 0.2 1.2e-11 44.1 0.2 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 GAM38932.1 - 6.5e-08 32.3 0.0 1.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 GAM38932.1 - 0.022 14.8 0.1 6.7 6.8 0.0 2.9 3 0 0 3 3 3 0 ACT domain DUF5614 PF18474.1 GAM38932.1 - 0.051 12.9 0.0 2.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5614) Limkain-b1 PF11608.8 GAM38932.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Limkain b1 CVNH PF08881.10 GAM38934.1 - 2.1e-17 63.6 0.2 6e-17 62.2 0.1 1.7 2 0 0 2 2 2 1 CVNH domain Gal-bind_lectin PF00337.22 GAM38934.1 - 0.0013 18.3 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Galactoside-binding lectin Peptidase_M4_C PF02868.15 GAM38935.1 - 3.2e-50 170.3 0.0 4.7e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 GAM38935.1 - 1.5e-23 83.9 0.1 2.8e-23 83.0 0.1 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain p450 PF00067.22 GAM38936.1 - 5.8e-36 124.2 0.1 1.2e-25 90.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Cgr1 PF03879.14 GAM38936.1 - 0.0061 16.9 3.1 0.011 16.1 3.1 1.3 1 0 0 1 1 1 1 Cgr1 family KH_1 PF00013.29 GAM38937.1 - 5.8e-10 38.9 0.0 3.4e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 KH domain NPP1 PF05630.11 GAM38938.1 - 4.3e-60 203.2 0.0 4.9e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Helicase_C PF00271.31 GAM38939.1 - 3.2e-16 59.7 0.0 4.6e-12 46.2 0.0 3.5 4 0 0 4 4 4 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 GAM38939.1 - 2.5e-05 24.9 0.5 2.5e-05 24.9 0.5 1.9 2 0 0 2 2 2 1 RecQ zinc-binding DEAD PF00270.29 GAM38939.1 - 0.0028 17.4 0.0 0.038 13.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Imm75 PF15660.6 GAM38939.1 - 0.14 12.4 0.2 0.65 10.3 0.0 2.1 2 0 0 2 2 2 0 Putative Immunity protein 75 PPR_2 PF13041.6 GAM38940.1 - 2.1e-08 34.2 0.2 0.24 11.6 0.0 5.1 4 2 2 6 6 6 3 PPR repeat family PPR PF01535.20 GAM38940.1 - 3e-05 23.9 4.8 0.11 12.8 0.0 5.6 6 0 0 6 6 6 1 PPR repeat PPR_3 PF13812.6 GAM38940.1 - 0.0032 17.5 0.0 9.7 6.4 0.0 4.0 3 1 1 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 GAM38940.1 - 0.013 14.8 0.0 0.032 13.6 0.0 1.6 1 1 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Herpes_UL17 PF04559.12 GAM38940.1 - 0.033 13.0 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL17 protein T6SS-SciN PF12790.7 GAM38940.1 - 0.037 13.7 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 Npa1 PF11707.8 GAM38940.1 - 0.1 11.9 0.1 0.37 10.1 0.0 1.9 2 1 0 2 2 2 0 Ribosome 60S biogenesis N-terminal PPR_1 PF12854.7 GAM38940.1 - 0.15 11.8 1.1 0.83 9.4 0.1 2.7 3 0 0 3 3 3 0 PPR repeat MRP-S25 PF13741.6 GAM38941.1 - 2.7e-84 282.3 4.5 3.1e-84 282.1 4.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 GAM38941.1 - 0.0075 16.5 2.6 2.5 8.4 0.3 2.6 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S23 SOG2 PF10428.9 GAM38942.1 - 3.3e-99 333.4 4.1 2.5e-50 172.2 0.0 5.2 4 2 1 5 5 5 2 RAM signalling pathway protein LRR_8 PF13855.6 GAM38942.1 - 4.3e-12 45.6 3.4 1e-06 28.4 0.2 2.5 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAM38942.1 - 2.2e-10 40.6 3.3 3e-05 24.3 0.1 3.4 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM38942.1 - 0.39 11.4 7.7 33 5.6 0.1 5.4 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 GAM38942.1 - 1.8 8.8 6.5 19 5.7 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat Tcp11 PF05794.13 GAM38943.1 - 8.5e-95 318.4 1.5 1e-94 318.2 1.5 1.1 1 0 0 1 1 1 1 T-complex protein 11 WHH PF14414.6 GAM38943.1 - 0.57 10.1 1.9 16 5.5 0.7 2.5 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH ABC_tran PF00005.27 GAM38944.1 - 1.2e-60 204.0 0.0 4.7e-29 101.7 0.0 3.4 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAM38944.1 - 7.1e-58 196.4 28.2 4.4e-45 154.5 15.0 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 GAM38944.1 - 7.1e-14 51.8 8.4 1.5e-05 24.6 3.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM38944.1 - 1.3e-08 34.5 0.9 0.0012 18.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM38944.1 - 4.1e-07 30.5 5.4 0.0071 16.8 1.0 4.2 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAM38944.1 - 1.1e-06 28.7 0.0 0.046 13.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 GAM38944.1 - 1.3e-06 28.7 0.1 0.0094 16.2 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_15 PF13175.6 GAM38944.1 - 1.4e-06 28.3 0.1 0.011 15.4 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 GAM38944.1 - 1e-05 25.1 0.0 0.11 12.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_21 PF13304.6 GAM38944.1 - 5e-05 23.3 0.0 0.4 10.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 GAM38944.1 - 0.00011 21.9 0.1 0.62 9.8 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 GAM38944.1 - 0.00035 21.0 4.0 1.3 9.5 0.2 4.2 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 GAM38944.1 - 0.00036 20.7 6.2 2 8.7 0.2 5.0 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 GAM38944.1 - 0.00051 19.0 1.3 0.62 8.8 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 GAM38944.1 - 0.001 18.7 0.8 3.5 7.1 0.0 3.9 4 1 0 4 4 4 1 AAA domain AAA_18 PF13238.6 GAM38944.1 - 0.0011 19.5 0.0 1.1 9.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 GAM38944.1 - 0.0017 18.3 0.1 0.78 9.7 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 GAM38944.1 - 0.0018 18.4 0.1 0.43 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 GAM38944.1 - 0.0037 17.8 0.0 3.7 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 GAM38944.1 - 0.0048 16.1 0.1 0.67 9.0 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_28 PF13521.6 GAM38944.1 - 0.0069 16.6 0.0 7.4 6.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.25 GAM38944.1 - 0.0084 15.8 0.0 0.34 10.5 0.0 2.9 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 GAM38944.1 - 0.0088 15.8 0.1 2.5 7.8 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein Ploopntkinase3 PF18751.1 GAM38944.1 - 0.0089 16.0 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 PRK PF00485.18 GAM38944.1 - 0.009 15.8 0.0 0.53 10.0 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 GAM38944.1 - 0.013 15.2 0.0 2.5 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAM38944.1 - 0.02 14.9 0.2 5.7 7.1 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase APS_kinase PF01583.20 GAM38944.1 - 0.033 14.1 0.0 13 5.7 0.0 3.0 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF87 PF01935.17 GAM38944.1 - 0.043 13.9 0.8 4.3 7.3 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 GAM38944.1 - 0.076 12.8 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 GAM38944.1 - 0.087 13.2 0.1 6.8 7.1 0.0 2.9 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 GAM38944.1 - 0.11 11.9 0.0 9.4 5.5 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family MoeA_C PF03454.15 GAM38944.1 - 0.16 12.1 0.0 20 5.4 0.0 2.7 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) Synapsin_N PF10581.9 GAM38944.1 - 0.18 11.8 0.0 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Synapsin N-terminal Zn_clus PF00172.18 GAM38945.1 - 3.2e-08 33.5 9.8 6.5e-08 32.6 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3418 PF11898.8 GAM38945.1 - 0.032 12.9 0.0 0.064 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) MFS_1 PF07690.16 GAM38946.1 - 9.4e-41 139.9 51.3 9.4e-41 139.9 51.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 GAM38947.1 - 6.6e-22 77.9 0.0 3.6e-19 68.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 adh_short PF00106.25 GAM38948.1 - 5.3e-19 68.4 0.0 6.3e-11 42.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM38948.1 - 2.1e-15 57.0 0.0 2.6e-14 53.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM38948.1 - 0.00031 20.7 0.0 0.0046 16.9 0.0 2.1 2 0 0 2 2 2 1 KR domain Ydc2-catalyt PF09159.10 GAM38949.1 - 4.5e-84 282.5 0.0 5.5e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.27 GAM38949.1 - 1.5e-07 31.0 0.3 3.6e-07 29.8 0.2 1.8 2 0 0 2 2 2 1 SAP domain Pox_A22 PF04848.13 GAM38949.1 - 0.015 15.4 0.1 18 5.5 0.1 3.2 3 0 0 3 3 3 0 Poxvirus A22 protein CTP_transf_like PF01467.26 GAM38951.1 - 1.6e-05 25.1 0.1 5.3e-05 23.4 0.0 1.8 2 1 1 3 3 3 1 Cytidylyltransferase-like 7TMR-HDED PF07697.11 GAM38951.1 - 0.076 13.1 0.0 0.098 12.8 0.0 1.4 1 1 0 1 1 1 0 7TM-HD extracellular Aim19 PF10315.9 GAM38952.1 - 2.8e-05 24.4 0.2 3.8e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF4536 PF15055.6 GAM38952.1 - 0.0037 17.5 0.1 0.016 15.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4536) DUF1977 PF09320.11 GAM38953.1 - 5.2e-29 100.6 0.1 8.9e-29 99.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 GAM38953.1 - 3.1e-22 78.4 0.2 5.7e-22 77.6 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Ufd2P_core PF10408.9 GAM38954.1 - 3.3e-220 733.0 7.8 4.2e-220 732.6 7.8 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 GAM38954.1 - 7.9e-27 93.2 3.2 1.1e-26 92.8 0.8 2.5 2 0 0 2 2 2 1 U-box domain CDT1_C PF16679.5 GAM38954.1 - 1 9.8 5.4 0.82 10.2 0.5 3.1 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain Steroid_dh PF02544.16 GAM38955.1 - 7.7e-15 55.2 3.6 1.6e-08 34.6 1.3 3.3 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 GAM38955.1 - 0.0065 16.0 0.5 0.017 14.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) SANT_DAMP1_like PF16282.5 GAM38957.1 - 3.1e-31 107.4 3.4 3.1e-31 107.4 3.4 1.9 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 GAM38957.1 - 0.00045 20.1 3.5 0.00045 20.1 3.5 3.2 2 1 1 3 3 3 1 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF4692 PF15763.5 GAM38957.1 - 4.5 7.7 9.5 0.35 11.3 4.1 1.8 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) EMP24_GP25L PF01105.24 GAM38958.1 - 6.2e-53 179.4 0.3 7.2e-53 179.2 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2721 PF11026.8 GAM38958.1 - 0.068 13.1 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) BioT2 PF15368.6 GAM38958.1 - 0.12 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis family BioT2 PNK3P PF08645.11 GAM38961.1 - 9.9e-58 194.4 0.3 1.6e-57 193.8 0.3 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 GAM38961.1 - 4.1e-27 95.1 0.0 4e-14 53.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain KTI12 PF08433.10 GAM38961.1 - 1.4e-06 28.0 0.1 0.002 17.7 0.0 2.4 1 1 1 2 2 2 2 Chromatin associated protein KTI12 Med18 PF09637.10 GAM38962.1 - 1.4e-44 152.9 0.0 1.5e-44 152.7 0.0 1.0 1 0 0 1 1 1 1 Med18 protein Sugar_tr PF00083.24 GAM38964.1 - 3.1e-77 260.4 24.8 3.5e-77 260.2 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM38964.1 - 5e-12 45.4 44.1 3.9e-09 35.9 19.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.13 GAM38965.1 - 8.4e-13 49.1 0.0 1e-12 48.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RNA_pol_Rpc34 PF05158.12 GAM38965.1 - 0.049 13.0 0.0 0.057 12.8 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit Ribonucleas_3_3 PF14622.6 GAM38966.1 - 2.3e-09 37.5 0.0 2.7e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 GAM38966.1 - 1.7e-08 35.0 0.0 3.7e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain S36_mt PF10937.8 GAM38967.1 - 4.8e-43 147.4 0.5 5.5e-43 147.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial RGS PF00615.19 GAM38968.1 - 3.3e-12 46.7 0.0 4.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain TipAS PF07739.13 GAM38968.1 - 0.18 12.4 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Abhydrolase_6 PF12697.7 GAM38969.1 - 6.2e-16 59.7 1.1 7.8e-16 59.3 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM38969.1 - 6e-07 29.0 0.0 9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM38969.1 - 0.0035 17.0 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pkinase PF00069.25 GAM38970.1 - 5e-27 94.9 0.0 6.4e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM38970.1 - 2.5e-14 53.2 0.0 3.4e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM38970.1 - 5.3e-07 28.7 0.0 7.8e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase CAP_N PF01213.19 GAM38970.1 - 0.027 13.9 1.4 0.044 13.3 1.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Rtt106 PF08512.12 GAM38971.1 - 6.6e-33 113.0 0.1 1.5e-32 111.8 0.1 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 GAM38971.1 - 0.0064 16.5 0.0 0.044 13.7 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Mpp10 PF04006.12 GAM38971.1 - 0.053 12.0 18.6 0.069 11.6 18.6 1.1 1 0 0 1 1 1 0 Mpp10 protein MazE_antitoxin PF04014.18 GAM38972.1 - 0.001 19.0 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin eIF-1a PF01176.19 GAM38972.1 - 0.017 14.9 0.0 0.057 13.2 0.0 1.9 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 KOW PF00467.29 GAM38972.1 - 0.017 15.0 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 KOW motif Ras PF00071.22 GAM38973.1 - 2.3e-45 154.1 0.0 2.7e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM38973.1 - 3.2e-22 79.0 0.0 4.1e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM38973.1 - 3.1e-06 26.7 0.0 4.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAM38973.1 - 0.0033 16.9 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAM38973.1 - 0.078 12.3 0.0 0.086 12.2 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 GAM38973.1 - 0.15 11.2 0.0 1.7 7.8 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain DUF1712 PF08217.11 GAM38974.1 - 2.2e-19 69.4 0.0 1.4e-16 60.1 0.0 2.7 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.19 GAM38975.1 - 2.8e-19 69.5 0.0 5.9e-19 68.5 0.0 1.5 1 1 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 GAM38975.1 - 0.13 12.5 0.2 0.7 10.2 0.2 2.2 1 1 0 1 1 1 0 Formyl transferase, C-terminal domain adh_short_C2 PF13561.6 GAM38976.1 - 1.7e-48 165.2 1.4 2.1e-48 164.9 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM38976.1 - 2e-43 148.1 0.2 2.6e-43 147.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM38976.1 - 9.1e-10 38.7 0.2 1.3e-09 38.3 0.2 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 GAM38976.1 - 0.063 13.2 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_C PF03720.15 GAM38976.1 - 0.068 13.6 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Epimerase PF01370.21 GAM38976.1 - 0.11 11.9 0.4 2.4 7.5 0.4 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 GAM38977.1 - 1.1e-25 90.3 69.8 2.4e-21 76.1 41.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_2 PF00891.18 GAM38978.1 - 4.2e-22 78.5 0.0 5.9e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain AA_permease PF00324.21 GAM38979.1 - 1.9e-118 396.1 37.5 1.9e-118 396.1 37.5 1.7 2 0 0 2 2 2 1 Amino acid permease Alg14 PF08660.11 GAM38979.1 - 3e-54 183.6 0.0 8.7e-54 182.1 0.0 1.8 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like AA_permease_2 PF13520.6 GAM38979.1 - 2.5e-36 125.4 39.2 2.5e-36 125.4 39.2 2.0 2 0 0 2 2 2 1 Amino acid permease Ring_hydroxyl_A PF00848.19 GAM38979.1 - 0.0087 16.0 0.1 0.016 15.2 0.1 1.3 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) NPCC PF08058.11 GAM38979.1 - 0.088 12.9 4.1 1.9 8.5 0.1 3.3 2 1 1 3 3 3 0 Nuclear pore complex component CoA_binding_3 PF13727.6 GAM38979.1 - 1.2 9.2 7.6 1.3 9.0 0.9 3.2 3 0 0 3 3 3 0 CoA-binding domain Ima1_N PF09779.9 GAM38980.1 - 2.6e-35 122.2 8.4 8.9e-35 120.5 8.4 2.0 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.7 GAM38980.1 - 0.046 13.7 3.9 4.3 7.5 0.4 2.6 2 0 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 GAM38980.1 - 0.077 13.0 6.7 0.025 14.5 2.9 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Fig1 PF12351.8 GAM38980.1 - 0.46 10.4 3.1 0.24 11.3 0.6 1.8 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 OrfB_Zn_ribbon PF07282.11 GAM38980.1 - 3.2 7.7 8.4 0.27 11.2 1.5 2.7 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Chorismate_synt PF01264.21 GAM38981.1 - 2.7e-124 414.1 0.1 3.1e-124 413.9 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase Kelch_5 PF13854.6 GAM38983.1 - 5.8e-05 23.0 3.0 0.0014 18.6 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 GAM38983.1 - 0.00013 22.1 7.1 1.6 9.2 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM38983.1 - 0.00073 19.5 0.2 0.75 9.8 0.0 3.0 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM38983.1 - 0.0072 16.3 0.3 0.19 11.7 0.1 2.9 2 0 0 2 2 2 1 Kelch motif SKG6 PF08693.10 GAM38983.1 - 0.13 11.7 0.1 0.29 10.6 0.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pkinase PF00069.25 GAM38984.1 - 4.8e-51 173.7 0.1 2.4e-33 115.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM38984.1 - 3.6e-24 85.4 0.2 5.8e-23 81.5 0.2 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM38984.1 - 3.3e-05 23.3 0.0 0.00011 21.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAM38984.1 - 4.9e-05 22.3 0.2 0.00016 20.6 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAM38984.1 - 0.0014 18.6 0.1 0.0064 16.4 0.1 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family zf-C2H2 PF00096.26 GAM38985.1 - 4.9e-13 48.8 11.1 2.6e-06 27.6 2.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM38985.1 - 2.8e-12 46.5 9.0 2.1e-07 31.1 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAM38985.1 - 2.1e-08 34.3 10.2 0.00083 20.0 1.4 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAM38985.1 - 4.4e-08 32.9 5.2 0.00052 19.9 0.3 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 GAM38985.1 - 4.1e-05 23.8 1.0 0.014 15.8 0.3 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAM38985.1 - 0.0019 18.4 7.6 0.38 11.1 0.2 3.8 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 GAM38985.1 - 0.015 15.1 4.2 1.2 8.9 0.5 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-Di19 PF05605.12 GAM38985.1 - 0.099 13.0 1.4 0.21 11.9 1.4 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.6 GAM38985.1 - 0.14 12.7 0.7 0.35 11.4 0.7 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2HE PF16278.5 GAM38985.1 - 0.19 12.2 1.9 6.5 7.3 0.3 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 GAM38985.1 - 0.51 10.6 2.9 22 5.4 0.2 2.4 1 1 1 2 2 2 0 LIM domain zf-BED PF02892.15 GAM38985.1 - 1.1 9.3 3.1 30 4.7 3.1 2.5 1 1 0 1 1 1 0 BED zinc finger FYVE PF01363.21 GAM38985.1 - 1.8 8.8 4.3 3.7 7.7 4.3 1.6 1 0 0 1 1 1 0 FYVE zinc finger C5HCH PF17982.1 GAM38985.1 - 3.5 7.8 6.0 16 5.7 0.4 2.6 1 1 1 2 2 2 0 NSD Cys-His rich domain ALG11_N PF15924.5 GAM38986.1 - 1.9e-82 276.3 0.1 2.7e-82 275.9 0.1 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 GAM38986.1 - 2.7e-19 69.3 0.0 4.7e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAM38986.1 - 2.7e-08 34.3 0.0 5.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAM38986.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 AAA_5 PF07728.14 GAM38986.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) 60KD_IMP PF02096.20 GAM38987.1 - 5.9e-15 55.6 0.0 2.3e-14 53.6 0.0 1.8 1 1 0 1 1 1 1 60Kd inner membrane protein DUF3180 PF11377.8 GAM38987.1 - 0.057 13.6 0.4 0.057 13.6 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) PP2C PF00481.21 GAM38988.1 - 5.2e-42 144.3 0.0 1.2e-41 143.0 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAM38988.1 - 0.00026 20.7 0.0 0.0005 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAM38988.1 - 0.00073 19.5 0.0 2.7 7.9 0.0 3.0 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Tcf25 PF04910.14 GAM38989.1 - 3.7e-81 272.9 0.4 5.2e-81 272.4 0.4 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PQ-loop PF04193.14 GAM38989.1 - 2.4e-18 65.6 4.2 5e-18 64.6 0.6 2.4 2 0 0 2 2 2 1 PQ loop repeat TPR_12 PF13424.6 GAM38989.1 - 0.00087 19.5 0.5 0.03 14.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM38989.1 - 0.073 13.2 0.1 0.29 11.3 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM38989.1 - 2 9.5 4.9 0.96 10.4 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 GAM38990.1 - 3.5e-77 255.0 16.4 4.7e-15 56.0 0.1 5.2 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM38990.1 - 1.2e-39 134.2 1.7 9.9e-06 26.0 0.0 7.7 4 1 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM38990.1 - 8.4e-33 108.7 6.2 0.00083 19.6 0.0 9.4 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 GAM38990.1 - 1.6e-29 101.0 17.0 0.00018 21.8 0.0 10.4 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 GAM38990.1 - 1.5e-28 98.4 10.2 3.6e-05 23.9 0.1 7.4 5 2 4 9 9 9 7 Ankyrin repeats (many copies) HET PF06985.11 GAM38990.1 - 0.0006 20.2 2.9 0.012 16.0 0.1 2.5 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Ribosomal_60s PF00428.19 GAM38991.1 - 1.2e-27 96.3 10.3 1.4e-27 96.0 10.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 GAM38991.1 - 0.24 9.8 2.3 0.31 9.5 2.3 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF3824 PF12868.7 GAM38991.1 - 0.48 11.1 5.5 0.65 10.6 5.5 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF2408 PF10303.9 GAM38992.1 - 1.3e-44 152.0 8.7 7e-28 97.9 2.3 4.9 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) IFT57 PF10498.9 GAM38992.1 - 0.0046 16.0 0.9 0.0085 15.1 0.2 1.8 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 Spc7 PF08317.11 GAM38992.1 - 0.036 13.0 0.2 0.036 13.0 0.2 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4201 PF13870.6 GAM38992.1 - 0.1 12.4 3.0 2.6 7.7 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) COG5 PF10392.9 GAM38992.1 - 0.22 11.7 5.3 0.27 11.4 0.3 3.1 3 1 0 3 3 3 0 Golgi transport complex subunit 5 NPV_P10 PF05531.12 GAM38992.1 - 0.9 10.0 2.8 86 3.7 0.2 4.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.7 GAM38992.1 - 1.8 8.1 6.8 2.3 7.7 0.2 2.8 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF4267 PF14087.6 GAM38993.1 - 2.8e-23 82.1 2.7 3.6e-23 81.8 2.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Tetraspanin PF00335.20 GAM38993.1 - 0.25 11.0 2.5 0.25 11.0 1.7 1.5 1 1 0 1 1 1 0 Tetraspanin family DUF4064 PF13273.6 GAM38993.1 - 0.3 11.4 5.2 0.086 13.1 2.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Aconitase PF00330.20 GAM38994.1 - 9.8e-146 486.4 0.0 1.2e-145 486.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAM38994.1 - 3.9e-40 137.2 0.0 6.1e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Fe-ADH PF00465.19 GAM38995.1 - 8e-68 228.9 0.0 1.1e-67 228.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 GAM38995.1 - 5.2e-12 46.0 0.1 2e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase NmrA PF05368.13 GAM38996.1 - 1.5e-25 90.1 0.0 1.9e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM38996.1 - 1.7e-11 44.4 0.0 2.4e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAM38996.1 - 7.7e-05 23.0 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 GAM38996.1 - 0.00035 19.8 0.0 0.0005 19.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 GAM38996.1 - 0.0006 20.2 0.0 0.0014 19.0 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 GAM38996.1 - 0.00095 19.1 0.0 0.002 18.1 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAM38996.1 - 0.0015 18.1 0.0 0.0035 16.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Toprim_4 PF13662.6 GAM38996.1 - 0.033 14.6 0.0 4.6 7.8 0.0 2.6 2 0 0 2 2 2 0 Toprim domain 3Beta_HSD PF01073.19 GAM38996.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family YBD PF17725.1 GAM38997.1 - 0.00091 19.1 0.0 0.84 9.5 0.0 2.3 2 0 0 2 2 2 2 YAP binding domain PhoLip_ATPase_N PF16209.5 GAM38997.1 - 0.085 12.6 3.4 2.8 7.7 0.3 3.0 2 1 1 3 3 3 0 Phospholipid-translocating ATPase N-terminal Sugar_tr PF00083.24 GAM38998.1 - 1e-85 288.3 18.0 1.4e-85 287.8 18.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM38998.1 - 1.1e-34 120.0 20.9 1.1e-34 120.0 20.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM38998.1 - 2.3e-26 92.4 0.9 4.4e-26 91.5 0.9 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1_like PF12832.7 GAM38998.1 - 5.5 5.7 17.4 1.7 7.4 7.7 2.3 2 0 0 2 2 2 0 MFS_1 like family FMN_dh PF01070.18 GAM38999.1 - 3e-103 345.5 0.2 6.1e-103 344.5 0.2 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 GAM38999.1 - 1.6e-18 66.6 0.0 3.8e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 GAM38999.1 - 1e-06 28.2 0.2 1.6e-06 27.6 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 GAM38999.1 - 3.9e-05 22.8 1.1 7.6e-05 21.9 0.2 1.9 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 GAM38999.1 - 0.047 13.0 0.5 3.4 6.9 0.1 2.8 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG Ribul_P_3_epim PF00834.19 GAM38999.1 - 0.062 12.7 0.1 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family DHO_dh PF01180.21 GAM38999.1 - 0.086 12.0 0.2 0.16 11.2 0.2 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 GAM38999.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Mannosidase_ig PF17786.1 GAM39000.1 - 1e-19 70.9 0.0 2.9e-19 69.5 0.0 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 GAM39000.1 - 7.9e-07 28.8 0.1 2.4e-06 27.2 0.1 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 GAM39000.1 - 9.2e-05 23.1 0.0 0.00024 21.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 GAM39000.1 - 0.0005 19.3 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 GAM39000.1 - 0.028 14.3 0.0 0.085 12.7 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain Cytotoxic PF09000.10 GAM39000.1 - 0.29 11.5 0.1 0.29 11.5 0.1 1.8 2 0 0 2 2 2 0 Cytotoxic Importin_rep_4 PF18808.1 GAM39001.1 - 2.4e-30 104.6 0.7 2.4e-30 104.6 0.7 4.1 4 1 0 4 4 3 1 Importin repeat Importin_rep_5 PF18816.1 GAM39001.1 - 7.6e-22 77.4 2.4 8.9e-22 77.1 0.4 2.3 2 0 0 2 2 1 1 Importin repeat HEAT_EZ PF13513.6 GAM39001.1 - 4.9e-21 74.8 14.2 7.7e-10 39.1 0.3 8.8 8 1 1 9 9 8 2 HEAT-like repeat HEAT PF02985.22 GAM39001.1 - 1.5e-16 59.1 14.2 0.0014 18.7 0.0 12.1 14 0 0 14 14 11 3 HEAT repeat Importin_rep_6 PF18829.1 GAM39001.1 - 1.2e-15 57.5 5.5 4.5e-15 55.7 1.0 3.0 3 0 0 3 3 2 1 Importin repeat 6 HEAT_2 PF13646.6 GAM39001.1 - 4.6e-15 55.8 16.5 0.00025 21.4 0.0 9.1 7 2 3 11 11 9 4 HEAT repeats MMS19_C PF12460.8 GAM39001.1 - 2.6e-10 40.0 7.4 2.9e-06 26.7 0.2 5.7 5 1 1 6 6 6 2 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 GAM39001.1 - 3.2e-10 40.5 0.7 0.0059 17.2 0.0 6.5 4 2 3 7 7 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAM39001.1 - 8.4e-08 32.4 1.5 0.062 13.3 0.1 5.7 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 GAM39001.1 - 5.8e-07 29.6 1.1 0.026 14.4 0.0 5.9 5 2 2 7 7 7 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 GAM39001.1 - 3.3e-06 26.8 1.1 0.14 11.7 0.2 6.3 6 1 2 8 8 8 1 CLASP N terminal DUF4042 PF13251.6 GAM39001.1 - 9.5e-06 25.4 0.2 11 5.7 0.0 5.7 6 0 0 6 6 6 0 Domain of unknown function (DUF4042) RIX1 PF08167.12 GAM39001.1 - 2.2e-05 24.3 0.2 0.011 15.5 0.1 3.9 3 1 1 4 4 3 1 rRNA processing/ribosome biogenesis IBN_N PF03810.19 GAM39001.1 - 8.9e-05 22.3 0.1 0.0033 17.3 0.0 3.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain TFCD_C PF12612.8 GAM39001.1 - 0.00072 19.4 0.2 0.66 9.8 0.1 3.0 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal RTP1_C1 PF10363.9 GAM39001.1 - 0.00088 19.4 2.8 0.37 11.0 0.5 5.1 5 0 0 5 5 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 GAM39001.1 - 0.0029 17.3 0.0 0.014 15.2 0.0 2.1 1 0 0 1 1 1 1 DNA alkylation repair enzyme MIF4G_like_2 PF09090.11 GAM39001.1 - 0.0039 16.7 0.7 0.032 13.7 0.1 2.3 2 0 0 2 2 2 1 MIF4G like Arm PF00514.23 GAM39001.1 - 0.0056 16.7 5.1 4.4 7.5 0.0 4.9 5 0 0 5 5 4 2 Armadillo/beta-catenin-like repeat IFRD PF05004.13 GAM39001.1 - 0.0063 15.7 9.1 0.13 11.3 0.3 4.6 3 2 2 5 5 5 1 Interferon-related developmental regulator (IFRD) RdRP_3 PF00998.23 GAM39001.1 - 0.011 14.4 0.0 0.02 13.6 0.0 1.3 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase V-ATPase_H_N PF03224.14 GAM39001.1 - 0.014 14.7 6.4 0.047 13.0 0.2 3.6 3 1 0 3 3 3 0 V-ATPase subunit H DUF3361 PF11841.8 GAM39001.1 - 0.041 13.8 4.8 0.13 12.2 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) Telomere_reg-2 PF10193.9 GAM39001.1 - 0.068 13.6 9.3 0.16 12.4 1.8 3.9 3 2 1 4 4 4 0 Telomere length regulation protein Ribonuc_2-5A PF06479.12 GAM39001.1 - 0.12 12.6 0.0 0.49 10.6 0.0 2.1 1 0 0 1 1 1 0 Ribonuclease 2-5A ROS_MUCR PF05443.11 GAM39001.1 - 0.13 12.3 0.3 0.35 10.9 0.3 1.7 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein DALR_1 PF05746.15 GAM39001.1 - 0.76 10.0 10.1 1.6 9.0 1.6 4.0 4 1 0 4 4 3 0 DALR anticodon binding domain CBS PF00571.28 GAM39002.1 - 1.1e-35 121.8 3.4 4.8e-09 36.5 0.0 5.1 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 GAM39002.1 - 4.3e-10 39.4 0.0 1.4e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 PB1 domain Ribosomal_S26e PF01283.19 GAM39003.1 - 9.5e-52 174.0 8.1 1.1e-51 173.8 8.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 GAM39003.1 - 0.022 14.7 0.5 0.053 13.5 0.0 1.9 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 GAM39003.1 - 0.065 13.1 0.3 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) F-box-like PF12937.7 GAM39004.1 - 2.6e-06 27.2 0.1 9.2e-06 25.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 GAM39004.1 - 0.0053 16.7 1.6 0.98 9.6 0.0 3.4 3 0 0 3 3 3 1 Leucine Rich repeat F-box PF00646.33 GAM39004.1 - 0.016 15.1 0.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 GAM39004.1 - 0.086 13.3 6.2 18 5.9 0.0 4.8 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM39004.1 - 0.09 13.4 0.1 54 4.9 0.1 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat Deltaretro_Tax PF05599.11 GAM39004.1 - 2.1 9.0 5.6 0.46 11.0 0.2 2.8 3 0 0 3 3 3 0 Deltaretrovirus Tax protein WSN PF02206.18 GAM39005.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF5069 PF16798.5 GAM39005.1 - 0.11 12.7 4.9 0.1 12.8 3.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5069) CDI PF02234.19 GAM39005.1 - 0.33 11.2 5.2 0.66 10.2 1.8 2.6 1 1 0 2 2 2 0 Cyclin-dependent kinase inhibitor Gon7 PF08738.10 GAM39005.1 - 1.1 9.4 13.8 0.24 11.5 0.9 2.8 1 1 1 2 2 2 0 Gon7 family ALMT PF11744.8 GAM39005.1 - 2.8 6.7 6.3 3.4 6.4 6.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter LANC_like PF05147.13 GAM39006.1 - 5.2e-25 87.8 0.0 3.9e-24 84.9 0.0 2.2 2 1 0 2 2 2 1 Lanthionine synthetase C-like protein zf-H2C2 PF09337.10 GAM39007.1 - 1.5e-15 57.1 1.4 3.2e-15 56.1 1.4 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 GAM39007.1 - 1.5e-10 41.0 1.0 2.7e-10 40.2 0.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 GAM39007.1 - 0.0011 19.1 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 GAM39007.1 - 0.016 15.9 0.7 0.035 14.8 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM39007.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Cpn60_TCP1 PF00118.24 GAM39008.1 - 3.9e-154 513.9 3.0 4.5e-154 513.7 3.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Beta_helix_2 PF18835.1 GAM39008.1 - 0.11 12.3 0.1 1.3 8.8 0.2 2.5 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase Peptidase_C14 PF00656.22 GAM39009.1 - 1.5e-62 211.8 0.0 2e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 GAM39009.1 - 0.22 11.5 0.5 0.75 9.7 0.0 2.2 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Ribo_biogen_C PF04034.13 GAM39010.1 - 2.8e-52 175.7 0.0 4.1e-52 175.2 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 GAM39010.1 - 2.4e-11 43.2 0.3 2.4e-11 43.2 0.3 1.7 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI CDC45 PF02724.14 GAM39010.1 - 0.59 8.4 10.2 0.84 7.9 10.2 1.4 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 GAM39010.1 - 0.98 8.7 22.0 1.7 7.9 22.0 1.3 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 GAM39010.1 - 7.8 6.0 13.2 11 5.5 13.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist VHS PF00790.19 GAM39011.1 - 2.6e-46 157.0 0.1 1.3e-45 154.7 0.0 2.2 2 1 1 3 3 3 1 VHS domain Alpha_adaptinC2 PF02883.20 GAM39011.1 - 5.4e-22 78.2 0.0 1.1e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 GAM39011.1 - 1.6e-20 73.1 0.5 7.6e-20 71.0 0.5 2.3 1 0 0 1 1 1 1 GAT domain GGA_N-GAT PF18308.1 GAM39011.1 - 8.4e-09 34.9 0.0 3.5e-06 26.5 0.0 2.8 2 0 0 2 2 2 2 GGA N-GAT domain DUF5344 PF17279.2 GAM39011.1 - 0.018 15.6 0.2 0.066 13.8 0.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Peptidase_S46 PF10459.9 GAM39011.1 - 0.29 9.7 3.4 0.45 9.1 3.4 1.2 1 0 0 1 1 1 0 Peptidase S46 CBS PF00571.28 GAM39012.1 - 3.7e-21 75.3 4.1 2e-08 34.6 0.0 5.1 5 0 0 5 5 5 4 CBS domain SPX PF03105.19 GAM39012.1 - 1.1 9.1 5.1 2.4 8.0 1.1 2.1 2 0 0 2 2 2 0 SPX domain SUIM_assoc PF16619.5 GAM39013.1 - 0.018 15.1 2.2 0.034 14.2 0.2 2.5 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Peptidase_S21 PF00716.17 GAM39013.1 - 6.7 6.3 12.1 0.25 11.0 5.7 1.7 2 0 0 2 2 2 0 Assemblin (Peptidase family S21) ADH_zinc_N_2 PF13602.6 GAM39014.1 - 1.1e-09 39.4 0.1 1.8e-09 38.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAM39014.1 - 3.6e-05 23.7 0.6 0.00016 21.6 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase GPP34 PF05719.11 GAM39015.1 - 8e-65 218.7 0.1 1.2e-64 218.1 0.1 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PP-binding PF00550.25 GAM39015.1 - 1.6e-09 38.0 0.1 2.9e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 GAM39015.1 - 0.0001 22.4 0.1 0.00025 21.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-carrier Fer4 PF00037.27 GAM39016.1 - 1e-13 50.5 17.0 3.6e-08 32.9 4.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 GAM39016.1 - 5e-13 49.4 10.5 7.6e-13 48.8 10.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 GAM39016.1 - 1.4e-10 41.9 7.7 1.9e-05 25.5 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 GAM39016.1 - 3.6e-10 39.8 21.7 3.4e-07 30.3 12.4 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 GAM39016.1 - 6.4e-10 39.0 21.0 6.2e-08 32.7 11.0 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 GAM39016.1 - 1.8e-09 37.6 5.3 0.0002 21.4 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 GAM39016.1 - 4.1e-07 30.4 19.4 0.00015 22.1 11.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 GAM39016.1 - 1.8e-06 27.8 17.5 0.00039 20.4 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 GAM39016.1 - 5.3e-06 26.2 12.1 0.01 15.9 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 GAM39016.1 - 2.3e-05 24.5 11.5 0.00029 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 GAM39016.1 - 0.00016 22.2 12.3 0.024 15.1 2.0 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 GAM39016.1 - 0.012 15.8 6.1 0.35 11.1 0.2 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_13 PF13370.6 GAM39016.1 - 0.045 14.3 15.2 0.73 10.4 4.3 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 GAM39016.1 - 0.053 13.7 9.2 1.2 9.3 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 GAM39016.1 - 0.067 14.2 15.7 0.12 13.4 3.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 GAM39016.1 - 0.13 12.5 6.0 0.54 10.4 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 GAM39016.1 - 0.4 11.6 11.5 3.4 8.6 2.3 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain SURF6 PF04935.12 GAM39017.1 - 3.8e-53 180.2 31.7 3.8e-53 180.2 31.7 4.0 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 GAM39017.1 - 3.6e-17 62.7 0.2 3.6e-17 62.7 0.2 8.1 6 2 2 8 8 8 1 60S ribosome biogenesis protein Rrp14 adh_short_C2 PF13561.6 GAM39018.1 - 1.4e-55 188.4 0.1 2e-55 187.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM39018.1 - 1.9e-44 151.5 2.6 2.5e-44 151.1 2.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Sugar_tr PF00083.24 GAM39018.1 - 4.6e-20 71.9 1.0 5.1e-20 71.8 1.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter KR PF08659.10 GAM39018.1 - 6.8e-14 52.2 1.4 9.7e-14 51.7 1.4 1.2 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 GAM39018.1 - 1.1e-07 31.1 1.8 1.6e-07 30.6 1.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_25 PF13649.6 GAM39018.1 - 0.059 14.1 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Rick_17kDa_Anti PF05433.15 GAM39019.1 - 1.4e-06 28.0 11.5 3.1e-06 26.9 11.5 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain Ribosomal_S2 PF00318.20 GAM39020.1 - 4.7e-70 235.2 0.0 8.8e-70 234.3 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S2 LDcluster4 PF18306.1 GAM39020.1 - 0.12 11.9 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 SLOG cluster4 family Glyco_hydro_31 PF01055.26 GAM39021.1 - 3.9e-81 273.5 0.1 5.1e-52 177.5 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GAM39021.1 - 3.9e-10 39.9 0.0 9.7e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like FAD_binding_4 PF01565.23 GAM39022.1 - 1.7e-21 76.4 0.6 3.2e-21 75.5 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM39022.1 - 0.0017 18.4 0.0 0.0042 17.2 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Mito_carr PF00153.27 GAM39023.1 - 1.6e-60 201.0 2.1 5.5e-20 71.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GTP_EFTU PF00009.27 GAM39024.1 - 2e-34 118.8 2.2 6.4e-33 113.9 2.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAM39024.1 - 4.9e-29 100.6 0.2 1.3e-28 99.2 0.2 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 GAM39024.1 - 2.4e-11 43.2 0.0 7.4e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 GAM39024.1 - 9.7e-11 41.8 0.1 2.7e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 GAM39024.1 - 0.00014 22.2 0.6 0.11 12.9 0.1 2.6 2 0 0 2 2 2 2 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 GAM39024.1 - 0.0011 19.0 2.6 0.13 12.2 0.2 2.5 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 GAM39024.1 - 0.0015 18.0 0.0 0.0042 16.5 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 GAM39024.1 - 0.0022 17.5 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 GAM39024.1 - 0.0099 15.4 0.3 0.043 13.4 0.3 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 GAM39024.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Ras family Prok-RING_1 PF14446.6 GAM39024.1 - 0.14 12.1 3.1 0.27 11.2 3.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Dynamin_N PF00350.23 GAM39024.1 - 0.36 10.9 3.0 6.4 6.8 0.2 3.1 2 1 1 3 3 3 0 Dynamin family DUF3886 PF13025.6 GAM39024.1 - 7.5 6.8 20.2 10 6.4 3.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3886) Hepatitis_core PF00906.20 GAM39025.1 - 1.2 8.6 4.9 2.1 7.8 4.9 1.4 1 0 0 1 1 1 0 Hepatitis core antigen HNH PF01844.23 GAM39026.1 - 0.18 12.0 1.2 0.63 10.3 1.2 2.0 1 1 0 1 1 1 0 HNH endonuclease HAD_2 PF13419.6 GAM39027.1 - 4.2e-13 49.8 0.0 8.3e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM39027.1 - 4e-06 27.3 0.0 2.3e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM39027.1 - 0.00028 20.9 0.0 0.00047 20.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Pneumovirus_M2 PF06436.11 GAM39027.1 - 0.06 12.8 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) HrcA PF01628.21 GAM39027.1 - 0.075 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 HrcA protein C terminal domain EI24 PF07264.11 GAM39028.1 - 7.4e-18 65.4 13.4 9.9e-18 65.0 13.4 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DC_STAMP PF07782.13 GAM39028.1 - 0.12 12.2 2.9 0.79 9.5 0.0 2.2 2 0 0 2 2 2 0 DC-STAMP-like protein Fer4_14 PF13394.6 GAM39028.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain FAD-oxidase_C PF02913.19 GAM39029.1 - 6.4e-65 219.2 0.0 8.5e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAM39029.1 - 3.1e-38 130.6 0.0 6.9e-38 129.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 GAM39029.1 - 0.0033 16.2 0.2 0.0053 15.5 0.2 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS ANF_receptor PF01094.28 GAM39029.1 - 0.0036 16.5 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region ESSS PF10183.9 GAM39029.1 - 0.15 12.3 0.0 15 5.8 0.0 2.7 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1 PF07690.16 GAM39030.1 - 1.6e-23 83.2 34.6 5.2e-23 81.5 29.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 GAM39032.1 - 4.3e-08 33.1 9.3 7.3e-08 32.4 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ceramidase_alk PF04734.13 GAM39034.1 - 9.7e-210 697.5 0.0 1.1e-209 697.3 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 GAM39034.1 - 5.5e-57 192.3 0.1 8.3e-57 191.7 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal BCAS2 PF05700.11 GAM39035.1 - 2.4e-67 226.6 1.7 2.7e-67 226.5 1.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Sld3_N PF18523.1 GAM39035.1 - 0.065 13.4 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Sld3 N-terminal domain RPA_interact_N PF14766.6 GAM39035.1 - 3.4 7.4 5.2 5.1 6.8 0.1 2.3 2 0 0 2 2 2 0 Replication protein A interacting N-terminal MFS_1 PF07690.16 GAM39036.1 - 8.6e-37 126.9 41.6 2.2e-36 125.5 35.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM39036.1 - 5.3e-09 35.0 4.3 9.7e-09 34.2 4.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gal_mutarotas_2 PF13802.6 GAM39036.1 - 0.034 14.5 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 Galactose mutarotase-like G0-G1_switch_2 PF15103.6 GAM39036.1 - 0.3 11.5 1.0 3.4 8.1 0.0 2.8 3 0 0 3 3 3 0 G0/G1 switch protein 2 MFS_3 PF05977.13 GAM39036.1 - 0.43 8.9 6.4 1.5 7.1 5.4 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector Snf7 PF03357.21 GAM39037.1 - 1.1e-35 122.7 21.3 1.1e-35 122.7 21.3 2.0 2 0 0 2 2 2 2 Snf7 Peptidase_S46 PF10459.9 GAM39037.1 - 0.074 11.7 12.4 0.091 11.4 12.4 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF3138 PF11336.8 GAM39037.1 - 0.084 11.5 8.3 0.1 11.2 6.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) RNA_pol_Rpb1_5 PF04998.17 GAM39037.1 - 0.28 10.6 2.8 0.35 10.3 2.8 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Atg14 PF10186.9 GAM39037.1 - 0.82 8.7 11.3 1.1 8.2 11.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NuA4 PF09340.10 GAM39037.1 - 3.6 7.5 11.8 0.68 9.9 2.8 3.6 3 1 0 3 3 3 0 Histone acetyltransferase subunit NuA4 Forkhead PF00250.18 GAM39038.1 - 7.6e-18 64.6 0.0 1.5e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain 2OG-FeII_Oxy_3 PF13640.6 GAM39038.1 - 1.8e-08 35.1 0.0 7e-08 33.3 0.0 2.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FHA PF00498.26 GAM39038.1 - 2.3e-05 24.6 0.0 5.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain p450 PF00067.22 GAM39039.1 - 4.5e-47 160.8 0.0 6.5e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 GAM39040.1 - 4.7e-18 65.6 0.0 7.9e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM39040.1 - 6.1e-10 39.7 0.0 1.8e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM39040.1 - 5.2e-08 33.5 0.0 1.5e-07 32.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM39040.1 - 1.1e-06 29.2 0.0 2.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM39040.1 - 2.8e-06 27.2 0.0 0.037 13.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 GAM39040.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 GAM39040.1 - 0.004 16.5 0.0 0.017 14.4 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 GAM39040.1 - 0.0052 16.3 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.9 GAM39040.1 - 0.026 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase FtsJ PF01728.19 GAM39040.1 - 0.2 11.7 0.1 0.63 10.1 0.0 1.8 2 1 0 3 3 3 0 FtsJ-like methyltransferase cNMP_binding PF00027.29 GAM39041.1 - 3.6e-41 139.1 0.0 2.2e-21 75.7 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain AMPK1_CBM PF16561.5 GAM39042.1 - 3.2e-21 75.4 0.4 6.3e-21 74.4 0.4 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 GAM39042.1 - 0.00065 20.0 0.1 0.0019 18.5 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF411 PF04214.13 GAM39042.1 - 0.026 14.4 1.7 4.6 7.2 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF CBM53 PF16760.5 GAM39042.1 - 0.15 12.7 0.2 0.3 11.7 0.2 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Draxin PF15550.6 GAM39042.1 - 3.7 7.3 11.8 9.4 6.0 11.8 1.7 1 1 0 1 1 1 0 Draxin VIT1 PF01988.19 GAM39043.1 - 1.1e-50 172.5 0.1 3.4e-50 170.9 0.1 1.8 1 0 0 1 1 1 1 VIT family p450 PF00067.22 GAM39043.1 - 5.8e-39 134.1 0.0 1.2e-38 133.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 PAP2_3 PF14378.6 GAM39043.1 - 2.2e-22 79.7 13.5 2.2e-22 79.7 13.5 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 GAM39043.1 - 2.4e-09 37.1 4.9 2.4e-09 37.1 4.9 2.8 3 0 0 3 3 3 1 PAP2 superfamily LCAT PF02450.15 GAM39044.1 - 2e-110 369.6 0.3 2.5e-110 369.3 0.3 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 GAM39044.1 - 0.0014 18.2 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.18 GAM39044.1 - 0.0039 16.8 0.0 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 2) LIDHydrolase PF10230.9 GAM39044.1 - 0.028 14.0 0.5 0.12 12.0 0.1 1.9 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 GAM39044.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Acetyltransf_1 PF00583.25 GAM39045.1 - 4.4e-20 72.1 0.0 6.8e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM39045.1 - 4.5e-13 49.2 0.0 6.3e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM39045.1 - 2.1e-12 47.3 0.1 3.5e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM39045.1 - 2e-10 40.5 0.1 3.4e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 GAM39045.1 - 1.4e-06 29.0 0.0 2.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM39045.1 - 1.9e-06 28.0 0.1 5.4e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 GAM39045.1 - 3.1e-05 23.7 0.1 5.5e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM39045.1 - 0.00017 21.6 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 GAM39045.1 - 0.019 14.5 0.0 0.027 14.1 0.0 1.3 1 1 0 1 1 1 0 GNAT acetyltransferase PanZ PF12568.8 GAM39045.1 - 0.025 14.3 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_13 PF13880.6 GAM39045.1 - 0.04 13.9 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_4 PF13420.7 GAM39045.1 - 0.06 13.5 0.0 0.078 13.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PPR_2 PF13041.6 GAM39046.1 - 0.0004 20.5 0.0 0.0084 16.3 0.0 2.7 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 GAM39046.1 - 0.0022 18.0 0.0 0.12 12.5 0.0 2.7 2 0 0 2 2 2 1 Pentatricopeptide repeat domain Pex24p PF06398.11 GAM39047.1 - 4.6e-05 22.6 9.8 6.5e-05 22.1 9.8 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4476 PF14771.6 GAM39047.1 - 0.0052 17.1 0.1 0.024 14.9 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4476) Seryl_tRNA_N PF02403.22 GAM39047.1 - 0.2 11.9 4.5 0.21 11.8 0.2 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Mis14 PF08641.12 GAM39048.1 - 1.4e-21 77.2 1.5 1.4e-21 77.2 1.5 3.4 3 1 0 3 3 3 1 Kinetochore protein Mis14 like CRAL_TRIO PF00650.20 GAM39049.1 - 2.4e-36 124.9 0.0 3.9e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAM39049.1 - 7.7e-09 35.6 0.4 1.8e-08 34.4 0.4 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAM39049.1 - 2.8e-05 24.3 0.0 4.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RasGAP PF00616.19 GAM39050.1 - 2.3e-59 200.6 0.3 2.3e-59 200.6 0.3 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 GAM39050.1 - 1.8e-30 105.9 2.1 1.8e-30 105.9 2.1 2.9 3 0 0 3 3 3 1 RasGAP C-terminus DUF4140 PF13600.6 GAM39050.1 - 0.047 14.1 0.5 0.25 11.8 0.5 2.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SOGA PF11365.8 GAM39050.1 - 0.13 13.4 4.7 0.8 10.9 0.4 3.2 2 0 0 2 2 2 0 Protein SOGA GvpL_GvpF PF06386.11 GAM39050.1 - 2.6 7.9 6.0 1.7 8.5 0.7 2.5 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DNA_pol_A_exo1 PF01612.20 GAM39051.1 - 8.7e-45 152.6 0.5 1.4e-44 151.9 0.5 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 GAM39051.1 - 8.2e-29 100.2 0.5 8.2e-28 96.9 0.7 2.6 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 GAM39051.1 - 5.1e-11 42.4 0.0 1.9e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 HRDC domain SR-25 PF10500.9 GAM39051.1 - 0.00038 20.2 15.1 0.0007 19.3 15.1 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 GAM39051.1 - 0.28 9.4 9.8 0.44 8.8 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein IMUP PF15761.5 GAM39051.1 - 1.4 9.6 16.3 3.6 8.3 16.3 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein CCDC106 PF15794.5 GAM39051.1 - 8.5 6.0 13.6 18 5.0 13.6 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Neur_chan_memb PF02932.16 GAM39051.1 - 9.8 6.2 6.6 23 4.9 6.6 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0203 PF05254.12 GAM39052.1 - 3.7e-26 91.2 4.3 4.3e-26 90.9 4.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 GAM39052.1 - 2.7e-05 24.4 1.5 5.1e-05 23.5 1.5 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 GAM39052.1 - 0.00049 20.1 4.5 0.0053 16.7 0.2 2.2 1 1 2 3 3 3 3 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 GAM39052.1 - 0.0051 16.5 3.9 0.077 12.7 0.3 2.1 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UCR_hinge PF02320.16 GAM39052.1 - 0.01 16.0 4.4 0.16 12.2 3.5 2.2 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF5339 PF17274.2 GAM39052.1 - 0.19 12.6 0.7 0.19 12.6 0.7 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5339) Myb_DNA-binding PF00249.31 GAM39053.1 - 0.00089 19.4 0.1 0.04 14.1 0.0 2.3 2 1 0 2 2 2 2 Myb-like DNA-binding domain Gpi1 PF05024.15 GAM39054.1 - 9.3e-79 263.9 7.9 1.7e-78 263.0 7.9 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.21 GAM39054.1 - 0.0078 15.6 0.4 0.017 14.4 0.4 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MutS_V PF00488.21 GAM39055.1 - 2.4e-81 272.3 0.1 4e-81 271.6 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAM39055.1 - 8.1e-37 127.3 1.3 8.1e-37 127.3 1.3 1.9 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 GAM39055.1 - 1e-17 64.7 0.9 2.2e-17 63.6 0.1 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 GAM39055.1 - 3.6e-17 62.5 1.4 3.6e-17 62.5 1.4 2.5 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.20 GAM39055.1 - 1.8e-15 57.2 0.0 2.1e-14 53.7 0.0 2.6 2 0 0 2 2 2 1 MutS domain I AAA_27 PF13514.6 GAM39055.1 - 0.081 12.5 0.0 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma70_r2 PF04542.14 GAM39055.1 - 0.2 11.4 0.6 0.68 9.8 0.1 2.1 2 0 0 2 2 2 0 Sigma-70 region 2 SET PF00856.28 GAM39056.1 - 5.8e-15 56.1 0.1 6.9e-14 52.6 0.0 2.4 2 1 0 2 2 2 1 SET domain SAF PF08666.12 GAM39056.1 - 0.054 14.1 0.0 4.6 7.9 0.0 2.3 2 0 0 2 2 2 0 SAF domain Fasciclin PF02469.22 GAM39058.1 - 1e-19 71.0 0.9 1.2e-15 57.8 0.6 2.1 2 0 0 2 2 2 2 Fasciclin domain YDG PF18657.1 GAM39058.1 - 5.6 7.2 8.0 0.98 9.7 3.0 2.3 2 2 0 2 2 2 0 YDG domain CDT1_C PF16679.5 GAM39060.1 - 9.2e-21 74.1 0.0 3.7e-20 72.2 0.0 2.0 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain Apolipoprotein PF01442.18 GAM39061.1 - 0.00094 19.1 6.8 0.0019 18.1 2.6 1.8 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 GAM39061.1 - 0.0036 17.9 10.9 0.14 12.8 3.4 2.2 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) Chlorosome_CsmC PF11098.8 GAM39061.1 - 0.027 14.4 1.0 0.04 13.9 1.0 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF3450 PF11932.8 GAM39061.1 - 0.033 13.5 0.7 0.043 13.1 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) NOG1_N PF17835.1 GAM39061.1 - 0.16 11.9 1.8 0.96 9.4 0.6 2.0 1 1 1 2 2 2 0 NOG1 N-terminal helical domain Mitofilin PF09731.9 GAM39061.1 - 0.37 9.6 11.6 0.44 9.3 11.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1283 PF06932.11 GAM39061.1 - 0.97 9.7 4.1 0.52 10.6 1.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1283) HSCB_C PF07743.13 GAM39061.1 - 7.6 7.1 7.1 21 5.7 7.1 1.9 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain Sugar_tr PF00083.24 GAM39062.1 - 4.8e-97 325.7 15.3 5.7e-97 325.4 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM39062.1 - 1e-18 67.4 41.0 7.8e-18 64.5 20.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM39062.1 - 0.042 12.3 6.9 0.3 9.4 1.4 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 GAM39062.1 - 0.23 12.0 3.2 0.78 10.3 3.2 2.0 1 0 0 1 1 1 0 Phage holin family 2 PrpF PF04303.13 GAM39063.1 - 9e-90 301.3 4.9 5.9e-89 298.6 4.9 1.9 1 1 0 1 1 1 1 PrpF protein DUF1381 PF07129.11 GAM39063.1 - 0.084 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) adh_short PF00106.25 GAM39064.1 - 2.1e-45 154.6 0.2 2.7e-45 154.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM39064.1 - 6.1e-42 143.8 0.2 9.2e-42 143.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAM39064.1 - 0.11 11.9 0.0 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 GAM39065.1 - 4.3e-35 121.3 28.4 4.3e-35 121.3 28.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM39065.1 - 5.8e-09 35.3 10.5 5.8e-09 35.3 10.5 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAM39065.1 - 0.0014 17.1 5.0 0.0025 16.3 5.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pom PF17251.2 GAM39065.1 - 0.097 12.0 0.1 10 5.4 0.0 2.2 1 1 0 2 2 2 0 Protochlamydia outer membrane protein ABM PF03992.16 GAM39066.1 - 2.2e-08 34.1 1.5 0.00013 22.1 0.4 3.3 3 0 0 3 3 3 2 Antibiotic biosynthesis monooxygenase FMO-like PF00743.19 GAM39067.1 - 5.8e-19 67.9 1.4 1.4e-17 63.3 0.5 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 GAM39067.1 - 7.4e-08 32.5 0.0 2.4e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAM39067.1 - 6.2e-05 22.3 0.1 0.014 14.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAM39067.1 - 8.9e-05 21.9 0.1 0.0051 16.1 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM39067.1 - 0.0017 18.4 0.0 0.056 13.4 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAM39067.1 - 0.0023 17.2 0.1 1.1 8.4 0.0 3.0 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM39067.1 - 0.015 15.8 0.2 0.69 10.5 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase S_locus_glycop PF00954.20 GAM39067.1 - 0.14 12.7 1.0 2.5 8.6 0.1 2.5 2 0 0 2 2 2 0 S-locus glycoprotein domain MFS_1 PF07690.16 GAM39068.1 - 1.8e-18 66.6 47.0 4.8e-18 65.2 45.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 GAM39068.1 - 5.7e-08 31.7 12.7 5.7e-08 31.7 12.7 2.1 2 0 0 2 2 2 1 MFS/sugar transport protein zf-C2H2 PF00096.26 GAM39069.1 - 1.4e-05 25.3 12.1 0.0053 17.1 1.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM39069.1 - 0.00025 21.3 3.8 0.00025 21.3 3.8 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAM39069.1 - 0.0013 19.4 11.5 0.067 14.1 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger TylF PF05711.11 GAM39069.1 - 0.22 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) zf-H2C2_5 PF13909.6 GAM39069.1 - 6.9 6.5 7.7 5 7.0 1.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain adh_short PF00106.25 GAM39070.1 - 3e-41 141.0 0.2 4e-41 140.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM39070.1 - 1.9e-32 112.7 0.1 2.5e-32 112.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM39070.1 - 7.8e-07 29.2 0.0 1.9e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAM39070.1 - 0.00053 19.9 0.1 0.0011 18.9 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM39070.1 - 0.0013 18.2 0.0 0.0037 16.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAM39070.1 - 0.0029 16.7 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Fungal_trans_2 PF11951.8 GAM39071.1 - 1.8e-05 23.8 2.0 0.00011 21.1 2.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain COG5 PF10392.9 GAM39072.1 - 1e-39 135.8 4.0 1e-39 135.8 4.0 2.8 3 1 1 4 4 4 1 Golgi transport complex subunit 5 ACC_central PF08326.12 GAM39072.1 - 0.0011 17.3 0.6 0.18 10.0 0.0 2.2 2 0 0 2 2 2 2 Acetyl-CoA carboxylase, central region COG2 PF06148.11 GAM39072.1 - 0.063 13.4 2.8 0.23 11.5 2.8 2.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 RTBV_P12 PF06361.11 GAM39072.1 - 0.14 12.5 0.1 0.55 10.7 0.0 2.0 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein DASH_Dad2 PF08654.10 GAM39072.1 - 0.27 11.7 2.4 0.42 11.1 0.5 2.4 3 0 0 3 3 3 0 DASH complex subunit Dad2 Aldolase_II PF00596.21 GAM39073.1 - 2.8e-48 164.3 0.1 3.6e-48 164.0 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SYS1 PF09801.9 GAM39074.1 - 3.8e-53 179.5 12.4 4.4e-53 179.3 12.4 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF4199 PF13858.6 GAM39074.1 - 1 9.7 10.8 13 6.1 8.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) COX6B PF02297.17 GAM39075.1 - 2e-23 82.4 1.7 2.7e-23 82.0 1.7 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Abi_2 PF07751.11 GAM39075.1 - 0.023 15.0 0.4 0.025 14.8 0.4 1.1 1 0 0 1 1 1 0 Abi-like protein UBA_2 PF08587.11 GAM39075.1 - 0.083 13.0 2.1 2.7 8.2 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) BOP1NT PF08145.12 GAM39076.1 - 4.4e-106 354.6 5.0 6.9e-106 353.9 5.0 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 GAM39076.1 - 4e-22 78.1 10.4 9.8e-09 35.7 0.4 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM39076.1 - 1.2e-05 25.5 0.0 0.011 16.1 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 GAM39077.1 - 3.5e-90 299.3 0.0 3.9e-44 150.3 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM39077.1 - 9.3e-21 73.4 1.6 3.2e-09 36.4 0.2 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 GAM39077.1 - 1.7e-13 50.6 0.0 4.1e-06 26.6 0.0 2.9 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAM39077.1 - 2e-13 50.8 0.2 0.0068 16.7 0.0 5.4 2 2 1 4 4 4 2 AAA domain AAA_16 PF13191.6 GAM39077.1 - 3.2e-13 50.4 1.8 0.00016 22.1 0.1 4.4 3 2 0 3 3 2 2 AAA ATPase domain AAA_2 PF07724.14 GAM39077.1 - 1e-11 45.2 0.0 0.00012 22.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAM39077.1 - 6.2e-11 42.5 0.7 0.00058 19.9 0.1 4.2 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 GAM39077.1 - 3e-10 40.4 0.0 0.00011 22.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 GAM39077.1 - 6.9e-09 35.4 0.0 0.0003 20.1 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 GAM39077.1 - 1.1e-08 35.4 0.0 0.0017 18.8 0.0 3.2 3 1 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 GAM39077.1 - 1.1e-07 32.0 0.0 0.0067 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 GAM39077.1 - 2.9e-07 30.1 0.4 0.018 14.4 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAM39077.1 - 3.2e-07 30.2 0.0 0.028 14.1 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_3 PF07726.11 GAM39077.1 - 4.3e-07 29.9 0.0 0.0041 17.0 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAM39077.1 - 5.2e-07 30.0 0.0 0.0073 16.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 GAM39077.1 - 1.3e-06 28.4 0.1 0.021 14.7 0.0 3.5 4 0 0 4 4 3 2 NACHT domain AAA_18 PF13238.6 GAM39077.1 - 1.4e-06 28.9 0.0 0.04 14.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 GAM39077.1 - 1.9e-06 27.3 0.0 0.038 13.2 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin TsaE PF02367.17 GAM39077.1 - 4.2e-06 26.8 0.0 0.039 14.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 GAM39077.1 - 8.5e-06 25.5 0.8 0.47 10.0 0.0 3.6 2 1 1 3 3 3 2 AAA domain ATPase PF06745.13 GAM39077.1 - 1.9e-05 24.1 0.3 0.47 9.8 0.0 3.5 3 1 1 4 4 3 2 KaiC ABC_tran PF00005.27 GAM39077.1 - 2.5e-05 24.8 0.0 0.34 11.4 0.0 3.0 3 0 0 3 3 2 2 ABC transporter AAA_7 PF12775.7 GAM39077.1 - 2.9e-05 23.7 0.0 0.12 11.9 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_17 PF13207.6 GAM39077.1 - 4.9e-05 23.8 1.9 0.092 13.2 0.1 3.8 4 1 0 4 4 2 1 AAA domain Cytidylate_kin2 PF13189.6 GAM39077.1 - 6.7e-05 23.1 0.0 0.0063 16.7 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family NB-ARC PF00931.22 GAM39077.1 - 9e-05 21.8 0.0 1 8.5 0.0 3.5 3 0 0 3 3 3 2 NB-ARC domain Rad17 PF03215.15 GAM39077.1 - 9e-05 22.5 0.0 0.48 10.3 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain PhoH PF02562.16 GAM39077.1 - 9.7e-05 21.9 0.0 0.15 11.5 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AFG1_ATPase PF03969.16 GAM39077.1 - 9.9e-05 21.4 0.0 0.025 13.5 0.0 2.4 2 0 0 2 2 2 1 AFG1-like ATPase Sigma54_activat PF00158.26 GAM39077.1 - 0.00017 21.3 0.0 0.28 10.9 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain ATPase_2 PF01637.18 GAM39077.1 - 0.00029 20.8 0.1 2 8.3 0.0 3.9 3 2 1 4 4 3 1 ATPase domain predominantly from Archaea TniB PF05621.11 GAM39077.1 - 0.00029 20.3 0.0 0.26 10.7 0.0 3.3 3 0 0 3 3 3 1 Bacterial TniB protein AAA_24 PF13479.6 GAM39077.1 - 0.00035 20.4 0.0 0.87 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 GAM39077.1 - 0.00092 18.4 0.0 1.5 7.8 0.0 2.5 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 GAM39077.1 - 0.00094 19.0 0.4 1.9 8.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 GAM39077.1 - 0.0011 18.1 0.0 0.034 13.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 GAM39077.1 - 0.0017 18.5 0.0 2.4 8.3 0.0 2.9 2 0 0 2 2 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 GAM39077.1 - 0.0018 18.1 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase SKI PF01202.22 GAM39077.1 - 0.0031 17.7 0.0 4 7.6 0.0 3.0 2 0 0 2 2 2 0 Shikimate kinase SRPRB PF09439.10 GAM39077.1 - 0.0033 16.9 0.0 13 5.2 0.0 3.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.6 GAM39077.1 - 0.048 14.0 2.8 13 6.1 0.5 3.4 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 GAM39077.1 - 0.057 13.3 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.15 GAM39077.1 - 0.073 13.0 0.0 11 5.9 0.0 2.9 2 1 1 3 3 3 0 NTPase PduV-EutP PF10662.9 GAM39077.1 - 0.13 12.0 0.0 10 5.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.9 GAM39077.1 - 0.13 11.4 0.0 8.1 5.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Vps4_C PF09336.10 GAM39077.1 - 0.14 12.2 0.6 11 6.2 0.0 3.7 3 1 0 3 3 3 0 Vps4 C terminal oligomerisation domain IPT PF01745.16 GAM39077.1 - 0.16 11.3 0.0 15 4.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_23 PF13476.6 GAM39077.1 - 0.49 10.9 2.7 14 6.1 0.0 3.4 4 0 0 4 4 3 0 AAA domain Snf7 PF03357.21 GAM39078.1 - 2.8e-33 114.9 13.7 2.8e-33 114.9 13.7 1.5 2 0 0 2 2 2 1 Snf7 Adenine_deam_C PF13382.6 GAM39078.1 - 0.039 13.3 0.5 0.071 12.5 0.5 1.4 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain PITH PF06201.13 GAM39079.1 - 2.2e-43 148.1 0.0 2.6e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 PITH domain HA2 PF04408.23 GAM39080.1 - 3.1e-17 62.8 0.0 6.2e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAM39080.1 - 3e-14 53.1 0.0 6.5e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAM39080.1 - 2e-12 47.4 0.0 4.2e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAM39080.1 - 2e-05 24.9 0.0 5.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 GAM39080.1 - 0.00021 21.1 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 GAM39080.1 - 0.00025 20.8 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM39080.1 - 0.0011 19.3 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 GAM39080.1 - 0.054 13.5 0.1 3.8 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 GAM39080.1 - 0.095 12.3 0.2 2.8 7.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 GAM39080.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 GAM39080.1 - 0.12 11.7 0.0 0.71 9.2 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 GAM39080.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GAM39080.1 - 0.2 12.2 0.0 0.52 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Herpes_ori_bp PF02399.15 GAM39080.1 - 0.2 9.7 0.0 0.3 9.1 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein FBPase_2 PF06874.11 GAM39080.1 - 0.2 9.9 0.1 0.31 9.3 0.1 1.2 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase Zeta_toxin PF06414.12 GAM39080.1 - 0.24 10.6 0.9 0.61 9.3 0.2 1.9 1 1 1 2 2 2 0 Zeta toxin CUE PF02845.16 GAM39081.1 - 1.7e-12 46.8 0.0 2.7e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain MOZART1 PF12554.8 GAM39082.1 - 1.6e-24 85.4 0.9 1.8e-24 85.2 0.9 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated PRA-PH PF01503.17 GAM39082.1 - 0.082 13.4 0.0 6.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase He_PIG PF05345.12 GAM39083.1 - 2e-15 56.7 14.6 0.00019 21.6 0.6 4.9 4 0 0 4 4 4 4 Putative Ig domain SKG6 PF08693.10 GAM39083.1 - 0.0014 17.9 3.8 0.0035 16.7 3.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.16 GAM39083.1 - 0.0049 15.7 0.0 0.0094 14.7 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF4448 PF14610.6 GAM39083.1 - 0.046 13.5 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Defensin_propep PF00879.18 GAM39083.1 - 0.11 12.8 0.1 0.52 10.6 0.1 2.2 1 0 0 1 1 1 0 Defensin propeptide FAM163 PF15069.6 GAM39083.1 - 0.19 12.2 0.0 0.76 10.2 0.0 2.0 2 0 0 2 2 2 0 FAM163 family TMEM154 PF15102.6 GAM39083.1 - 0.21 11.5 0.0 0.21 11.5 0.0 2.2 3 0 0 3 3 3 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 GAM39083.1 - 0.78 9.6 2.7 1.4 8.7 2.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PP2C PF00481.21 GAM39084.1 - 4e-80 269.2 0.1 5.8e-80 268.6 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C CTP_transf_like PF01467.26 GAM39085.1 - 3.2e-30 105.2 0.0 5.9e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Granulin PF00396.18 GAM39086.1 - 0.024 14.9 2.4 0.056 13.8 2.4 1.5 1 0 0 1 1 1 0 Granulin Asp PF00026.23 GAM39087.1 - 1.3e-38 133.2 0.8 1.6e-38 133.0 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM39087.1 - 1.6e-08 35.0 3.7 3.5e-06 27.4 2.1 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal EamA PF00892.20 GAM39088.1 - 2.4e-13 50.4 24.1 1.5e-08 34.9 6.8 2.8 2 1 0 2 2 2 2 EamA-like transporter family COX15-CtaA PF02628.15 GAM39088.1 - 0.19 10.8 3.9 0.3 10.1 3.9 1.3 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein UTP25 PF06862.12 GAM39089.1 - 1e-197 657.7 0.4 1.2e-197 657.4 0.4 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 GAM39089.1 - 0.00094 19.0 0.0 0.039 13.7 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM39089.1 - 0.0063 16.8 0.0 0.04 14.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain JAB PF01398.21 GAM39090.1 - 4.4e-20 71.8 0.0 8.2e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 GAM39090.1 - 3.8e-19 69.1 0.2 6.7e-19 68.4 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 GAM39090.1 - 6.1e-05 23.1 0.0 0.00015 21.8 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) TFIID-18kDa PF02269.16 GAM39091.1 - 5.6e-22 77.6 0.0 9.4e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 GAM39091.1 - 0.00025 21.1 0.4 0.00049 20.2 0.2 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAM39091.1 - 0.00029 21.2 0.1 0.0006 20.1 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 GAM39091.1 - 0.0016 18.8 0.1 0.0016 18.8 0.1 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 GAM39091.1 - 0.0019 18.2 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 GAM39091.1 - 0.0095 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 GAM39091.1 - 0.028 14.7 1.7 0.032 14.5 0.1 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 GAM39091.1 - 0.036 14.3 0.1 0.064 13.4 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) PPR_2 PF13041.6 GAM39092.1 - 9e-20 70.6 5.2 2.8e-07 30.6 0.0 6.0 5 2 2 7 7 7 3 PPR repeat family PPR PF01535.20 GAM39092.1 - 3.1e-12 45.9 7.7 0.0047 17.1 0.0 6.3 8 0 0 8 8 8 4 PPR repeat PPR_3 PF13812.6 GAM39092.1 - 2.2e-11 43.6 0.3 0.0068 16.5 0.0 4.8 3 2 3 6 6 6 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAM39092.1 - 5.5e-06 26.0 1.2 1.2 8.9 0.0 4.8 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 GAM39092.1 - 2.8e-05 23.6 0.5 0.017 14.5 0.2 3.4 2 2 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GAM39092.1 - 0.074 13.6 0.1 0.23 12.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PORR PF11955.8 GAM39092.1 - 0.11 11.4 1.1 4.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Plant organelle RNA recognition domain Macoilin PF09726.9 GAM39093.1 - 0.12 10.9 6.4 0.13 10.8 6.4 1.0 1 0 0 1 1 1 0 Macoilin family CFEM PF05730.11 GAM39093.1 - 0.27 11.3 13.6 0.77 9.9 13.6 1.9 1 1 0 1 1 1 0 CFEM domain HECT PF00632.25 GAM39094.1 - 1.6e-98 330.0 0.0 2.3e-98 329.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 GAM39094.1 - 4.9e-34 116.1 22.0 3.5e-12 46.2 2.7 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.30 GAM39094.1 - 4.6e-18 65.4 0.0 1.1e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.22 GAM39094.1 - 7.6e-06 25.7 0.0 2.4e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GGDEF PF00990.21 GAM39094.1 - 0.092 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain DivIC PF04977.15 GAM39094.1 - 0.61 9.9 4.1 1.4 8.7 4.1 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF724 PF05266.14 GAM39094.1 - 3 7.6 5.8 5.4 6.8 5.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Metallophos_2 PF12850.7 GAM39095.1 - 1.9e-12 47.7 0.0 2.4e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.19 GAM39096.1 - 1.7e-32 112.8 0.0 2.2e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V KR PF08659.10 GAM39096.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 KR domain B12-binding PF02310.19 GAM39096.1 - 0.12 12.4 0.3 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 B12 binding domain NIF PF03031.18 GAM39097.1 - 5e-57 192.0 0.0 7.4e-57 191.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IF-2B PF01008.17 GAM39098.1 - 1.6e-61 208.0 1.1 2.3e-37 128.7 0.3 2.7 2 1 0 2 2 2 2 Initiation factor 2 subunit family Ribosom_S12_S23 PF00164.25 GAM39099.1 - 1.3e-50 169.8 0.8 1.6e-50 169.5 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF5315 PF17242.2 GAM39100.1 - 7.7e-24 83.3 2.8 7.7e-24 83.3 2.8 1.8 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) Cluap1 PF10234.9 GAM39100.1 - 0.017 14.5 3.7 0.024 14.1 3.7 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 AIM5 PF17050.5 GAM39101.1 - 2.1e-11 44.5 0.9 3e-11 43.9 0.9 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Ribosomal_L17 PF01196.19 GAM39102.1 - 8e-35 119.6 1.4 9.7e-35 119.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L17 Molybdopterin_N PF18364.1 GAM39102.1 - 0.057 13.4 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain TRAF_BIRC3_bd PF16673.5 GAM39102.1 - 0.12 12.2 2.9 3.8 7.4 0.4 2.6 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF5093 PF17011.5 GAM39102.1 - 0.35 11.1 3.9 0.62 10.4 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) cwf18 PF08315.12 GAM39103.1 - 2e-42 145.0 10.2 2e-42 145.0 10.2 1.6 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor SUZ PF12752.7 GAM39104.1 - 5.3e-14 52.7 11.2 5.3e-14 52.7 11.2 4.0 3 1 0 3 3 3 1 SUZ domain R3H PF01424.22 GAM39104.1 - 6e-08 32.6 0.0 1.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 R3H domain TPR_12 PF13424.6 GAM39105.1 - 1.5e-09 38.0 7.2 0.00026 21.2 0.1 5.0 5 2 0 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAM39105.1 - 6.3e-05 22.6 1.7 0.05 13.4 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM39105.1 - 6.9e-05 22.7 9.9 0.055 13.6 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM39105.1 - 7.8e-05 22.2 1.9 9.2e-05 22.0 0.4 1.9 2 0 0 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 GAM39105.1 - 0.00012 21.8 4.5 0.58 10.1 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM39105.1 - 0.0032 17.4 7.2 2.4 8.4 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM39105.1 - 0.004 17.6 0.2 0.42 11.2 0.0 4.1 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM39105.1 - 0.031 14.9 8.2 0.97 10.1 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CBP_GIL PF10995.8 GAM39105.1 - 0.039 12.6 0.6 0.068 11.8 0.6 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis GIL TPR_8 PF13181.6 GAM39105.1 - 0.07 13.4 0.1 27 5.3 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAM39105.1 - 0.11 13.2 9.6 21 6.1 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM39105.1 - 0.15 12.3 1.8 6.7 7.0 0.9 3.4 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 GAM39105.1 - 1.1 10.3 14.0 47 5.2 0.1 6.5 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF4375 PF14300.6 GAM39106.1 - 0.037 14.3 7.1 3.1 8.1 0.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4375) WD40 PF00400.32 GAM39107.1 - 3.3e-38 129.0 17.4 1.3e-10 41.7 0.1 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM39107.1 - 1.8e-10 41.0 0.8 0.023 15.0 0.1 4.5 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 GAM39107.1 - 4.9e-07 29.0 1.1 2.6e-06 26.6 0.1 2.6 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 GAM39107.1 - 1.1e-05 24.3 6.1 0.22 10.1 0.1 4.8 4 1 0 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAM39107.1 - 0.00069 18.7 0.0 0.54 9.2 0.0 3.6 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 GAM39107.1 - 0.012 15.3 3.5 0.49 10.1 0.1 4.0 3 1 1 5 5 5 0 TUP1-like enhancer of split Frtz PF11768.8 GAM39107.1 - 0.024 13.0 0.0 0.059 11.7 0.0 1.5 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF1513 PF07433.11 GAM39107.1 - 0.1 11.7 1.2 3 6.9 0.0 2.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1513) Tctex-1 PF03645.13 GAM39108.1 - 1.5e-34 118.3 0.0 1.8e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.15 GAM39109.1 - 1.3e-13 51.1 8.6 2.3e-13 50.4 5.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4131 PF13567.6 GAM39109.1 - 7.5 6.2 8.4 1.3 8.7 2.0 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) CDC45 PF02724.14 GAM39110.1 - 7 4.8 10.6 12 4.1 10.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SUR7 PF06687.12 GAM39111.1 - 2.7e-44 151.3 20.2 5.2e-44 150.4 12.4 1.4 1 1 1 2 2 2 2 SUR7/PalI family WBP-1 PF11669.8 GAM39111.1 - 0.22 12.2 1.7 0.57 10.8 0.1 2.5 3 0 0 3 3 3 0 WW domain-binding protein 1 Shisa PF13908.6 GAM39111.1 - 0.79 9.9 6.5 1.5 9.0 1.4 2.3 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Arteri_Gl PF00951.18 GAM39111.1 - 0.95 9.2 6.9 0.094 12.5 2.3 1.6 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein Claudin_2 PF13903.6 GAM39111.1 - 1.5 8.5 12.7 0.76 9.5 5.2 2.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Bac_rhodopsin PF01036.18 GAM39113.1 - 1.2e-33 116.6 21.4 1.6e-33 116.2 21.4 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein CENP-I PF07778.11 GAM39113.1 - 0.069 11.9 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 Mis6 TMEM220 PF15071.6 GAM39113.1 - 0.23 12.2 5.1 6.9 7.5 0.7 2.6 2 0 0 2 2 2 0 Transmembrane family 220, helix YrhC PF14143.6 GAM39113.1 - 3.1 7.9 5.6 1.2 9.3 0.3 2.7 3 0 0 3 3 3 0 YrhC-like protein Acetyltransf_1 PF00583.25 GAM39114.1 - 2e-11 44.1 0.0 3.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAM39114.1 - 2.5e-07 30.6 0.1 4.1e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 GAM39114.1 - 1.2e-06 28.5 0.1 1.8e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM39114.1 - 2.1e-05 24.9 0.0 4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM39114.1 - 0.0069 16.5 0.2 0.012 15.7 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3176 PF11374.8 GAM39115.1 - 7.8e-34 116.1 0.1 2.2e-33 114.6 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Pkinase PF00069.25 GAM39115.1 - 1.2e-10 41.2 0.2 3.3e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Cnd1 PF12717.7 GAM39115.1 - 2.7e-06 27.5 0.0 1.1e-05 25.6 0.0 1.9 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAM39115.1 - 7.2e-05 23.2 0.0 0.027 15.0 0.0 2.9 2 0 0 2 2 2 1 HEAT-like repeat Pkinase_Tyr PF07714.17 GAM39115.1 - 0.0001 21.7 0.0 0.00028 20.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT PF02985.22 GAM39115.1 - 0.00012 22.0 0.3 0.35 11.2 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat Nitr_red_assoc PF09655.10 GAM39115.1 - 0.12 13.0 3.0 0.42 11.3 3.0 1.8 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Dot_icm_IcmQ PF09475.10 GAM39115.1 - 0.17 11.4 1.0 0.48 9.9 0.6 1.9 2 0 0 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Mito_carr PF00153.27 GAM39116.1 - 2.7e-66 219.6 0.5 3.4e-24 84.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein AIP3 PF03915.13 GAM39117.1 - 5.9e-159 529.5 6.4 5.9e-159 529.5 6.4 1.3 2 0 0 2 2 2 1 Actin interacting protein 3 Lectin_N PF03954.14 GAM39117.1 - 0.0019 17.9 0.1 0.0099 15.6 0.1 2.2 1 1 0 1 1 1 1 Hepatic lectin, N-terminal domain NPV_P10 PF05531.12 GAM39117.1 - 0.028 14.9 0.1 0.028 14.9 0.1 3.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 GAM39117.1 - 0.041 13.9 3.4 0.41 10.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 GAM39117.1 - 0.043 13.7 0.6 0.4 10.5 0.2 2.5 3 0 0 3 3 3 0 Sec34-like family DASH_Duo1 PF08651.10 GAM39117.1 - 0.1 12.4 0.6 6.8 6.5 0.0 3.0 3 0 0 3 3 3 0 DASH complex subunit Duo1 LsmAD PF06741.13 GAM39119.1 - 7.8e-27 93.6 1.2 7.8e-27 93.6 1.2 2.1 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 GAM39119.1 - 1.1e-21 76.7 0.1 2.2e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain HLH PF00010.26 GAM39122.1 - 2.3e-12 46.6 0.0 8.6e-12 44.8 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Got1 PF04178.12 GAM39123.1 - 1.9e-24 86.3 6.9 2.3e-24 86.0 6.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family tRNA_lig_CPD PF08302.11 GAM39124.1 - 4.6e-91 304.8 0.1 6.8e-91 304.2 0.1 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 GAM39124.1 - 1.8e-85 286.3 0.0 3e-85 285.6 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 GAM39124.1 - 7.6e-50 169.3 0.2 1.7e-49 168.1 0.2 1.6 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 GAM39124.1 - 0.13 12.8 0.1 1.4 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ank_5 PF13857.6 GAM39125.1 - 1.4e-10 41.2 0.1 9.2e-09 35.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM39125.1 - 3.5e-07 30.6 0.0 2.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM39125.1 - 2e-06 27.7 0.2 2.5e-05 24.3 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 GAM39125.1 - 5.7e-06 26.8 0.1 1.1e-05 25.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAM39125.1 - 0.002 18.5 0.1 0.0052 17.2 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeat VHL_C PF17211.3 GAM39125.1 - 0.066 13.2 0.1 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 VHL box domain Jagunal PF07086.12 GAM39128.1 - 0.016 15.3 0.3 0.016 15.3 0.3 1.9 1 1 1 2 2 2 0 Jagunal, ER re-organisation during oogenesis UL41A PF17591.2 GAM39128.1 - 0.2 11.7 4.1 0.39 10.8 0.1 2.8 3 0 0 3 3 3 0 Herpesvirus UL41A UPF0242 PF06785.11 GAM39128.1 - 0.52 10.4 1.3 1 9.4 1.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fungal_trans_2 PF11951.8 GAM39129.1 - 2.3e-08 33.2 0.4 1.6e-06 27.2 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF1295 PF06966.12 GAM39130.1 - 9.3e-40 136.6 7.2 1.1e-39 136.4 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 GAM39130.1 - 0.15 12.5 1.1 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.20 GAM39131.1 - 2e-104 349.9 0.0 1.2e-98 330.9 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 GAM39131.1 - 1.8e-19 69.9 0.0 3.7e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Toprim domain ADH_zinc_N PF00107.26 GAM39132.1 - 1.6e-11 44.3 0.1 3.6e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM39132.1 - 1.6e-09 37.6 0.1 8.5e-09 35.3 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM39132.1 - 0.058 14.4 0.0 0.21 12.6 0.0 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase OrsD PF12013.8 GAM39133.1 - 8.5e-25 87.4 0.0 1.6e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 GAM39133.1 - 0.31 12.0 3.0 4.2 8.5 0.3 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-UBP PF02148.19 GAM39133.1 - 0.46 10.8 2.1 7.3 7.0 0.3 2.5 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein FAD_binding_3 PF01494.19 GAM39134.1 - 6e-57 193.5 0.0 7.5e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 GAM39134.1 - 1.9e-08 33.5 0.1 0.0014 17.4 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 GAM39134.1 - 1.9e-08 34.3 0.1 0.00053 19.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM39134.1 - 8e-07 28.5 0.1 0.0089 15.1 0.1 3.0 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.27 GAM39134.1 - 3e-06 27.7 0.3 0.1 13.2 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM39134.1 - 0.00016 21.0 0.0 0.13 11.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM39134.1 - 0.0002 21.5 0.1 0.0015 18.7 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM39134.1 - 0.0027 17.0 0.3 0.0052 16.1 0.2 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 GAM39134.1 - 0.0096 15.0 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 GAM39134.1 - 0.01 14.9 0.2 0.023 13.7 0.2 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 GAM39134.1 - 0.016 14.5 1.1 0.018 14.3 0.1 1.5 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 GAM39134.1 - 0.062 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 GAM39134.1 - 0.067 12.0 1.7 4.2 6.1 0.1 2.4 2 1 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 GAM39134.1 - 0.086 12.0 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 GAM39134.1 - 0.34 10.2 1.6 3 7.1 1.4 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase PTS_2-RNA PF01885.16 GAM39135.1 - 2.8e-65 219.8 0.0 3.8e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.17 GAM39135.1 - 0.091 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 La domain Dioxygenase_C PF00775.21 GAM39136.1 - 4.5e-49 166.4 0.0 6e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 GAM39136.1 - 3e-28 97.5 0.1 4.7e-28 96.8 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 GAM39136.1 - 8.2e-07 29.2 0.0 3.4e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 GAM39136.1 - 0.026 14.5 0.0 0.66 10.0 0.0 2.5 3 0 0 3 3 3 0 CarboxypepD_reg-like domain SpaA PF17802.1 GAM39136.1 - 0.057 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Prealbumin-like fold domain Abhydrolase_1 PF00561.20 GAM39137.1 - 6e-24 85.1 0.1 2.1e-20 73.5 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM39137.1 - 5.7e-20 71.6 0.5 1.5e-12 47.3 0.4 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM39137.1 - 2.5e-16 61.0 0.1 1.2e-15 58.7 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 GAM39137.1 - 2.8e-05 23.0 0.0 3.8e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Ndr family DLH PF01738.18 GAM39137.1 - 7.3e-05 22.4 0.1 0.036 13.6 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAM39137.1 - 0.00011 21.7 0.0 0.26 10.7 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF915 PF06028.11 GAM39137.1 - 0.00013 21.4 0.0 0.0012 18.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 GAM39137.1 - 0.00015 21.5 0.4 0.00035 20.3 0.2 1.6 1 1 1 2 2 2 1 Putative esterase Chlorophyllase2 PF12740.7 GAM39137.1 - 0.00018 20.5 0.3 0.00063 18.7 0.3 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 GAM39137.1 - 0.0075 16.1 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 GAM39137.1 - 0.0087 15.8 0.1 0.017 14.9 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 GAM39137.1 - 0.013 15.4 0.0 0.046 13.6 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_2 PF02230.16 GAM39137.1 - 0.014 15.3 0.4 0.36 10.6 0.0 2.5 2 1 0 3 3 3 0 Phospholipase/Carboxylesterase Chlorophyllase PF07224.11 GAM39137.1 - 0.021 13.8 0.8 0.041 12.9 0.8 1.5 1 1 0 1 1 1 0 Chlorophyllase BAAT_C PF08840.11 GAM39137.1 - 0.029 14.3 0.0 0.067 13.1 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.13 GAM39137.1 - 0.044 12.3 1.6 0.11 11.0 0.2 1.9 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II LCAT PF02450.15 GAM39137.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 GAM39137.1 - 0.15 11.8 0.5 0.55 9.9 0.1 1.9 2 0 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.20 GAM39137.1 - 0.18 11.9 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Fungal_trans PF04082.18 GAM39138.1 - 1.1e-18 67.3 0.1 2e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SnoaL_2 PF12680.7 GAM39139.1 - 0.052 14.2 0.2 0.21 12.2 0.2 1.9 1 1 0 1 1 1 0 SnoaL-like domain CoA_transf_3 PF02515.17 GAM39140.1 - 5.6e-43 147.5 0.0 3.3e-41 141.6 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Stb3 PF10330.9 GAM39142.1 - 8e-39 131.6 0.0 1.2e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Mito_carr PF00153.27 GAM39144.1 - 5.3e-64 212.2 6.4 1.6e-22 79.2 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Kri1_C PF12936.7 GAM39145.1 - 1.8e-31 108.2 0.1 1.8e-31 108.2 0.1 4.3 3 1 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 GAM39145.1 - 4.2e-30 104.3 23.8 4.2e-30 104.3 23.8 5.5 6 0 0 6 6 6 1 KRI1-like family OMP_b-brl PF13505.6 GAM39145.1 - 0.21 11.7 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Sulfotransfer_3 PF13469.6 GAM39145.1 - 4.5 7.6 9.2 0.58 10.5 0.1 3.3 2 1 0 2 2 2 0 Sulfotransferase family VASt PF16016.5 GAM39146.1 - 2.1e-38 132.1 0.1 4.6e-38 131.0 0.1 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 GAM39146.1 - 5.2e-16 59.1 0.0 9.9e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 GAM39146.1 - 4.4e-08 33.6 0.1 1.5e-07 31.9 0.1 2.0 1 0 0 1 1 1 1 PH domain BAR PF03114.18 GAM39146.1 - 0.00054 19.7 0.1 0.0011 18.7 0.1 1.5 1 0 0 1 1 1 1 BAR domain GRAM PF02893.20 GAM39146.1 - 0.00085 19.2 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Sen15 PF09631.10 GAM39147.1 - 5.9e-19 68.2 0.0 1.6e-16 60.4 0.0 2.2 1 1 0 1 1 1 1 Sen15 protein UAA PF08449.11 GAM39148.1 - 1.7e-40 139.1 14.3 2.7e-40 138.5 14.3 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAM39148.1 - 7.8e-07 29.3 24.5 3.4e-05 24.0 7.2 3.2 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 GAM39148.1 - 1.6e-05 24.2 2.3 0.072 12.3 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 GAM39148.1 - 0.025 14.0 5.7 0.74 9.1 0.4 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family Cellulase PF00150.18 GAM39149.1 - 4.9e-13 49.1 0.3 7.3e-13 48.6 0.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CARDB PF07705.11 GAM39149.1 - 0.16 12.3 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 CARDB p450 PF00067.22 GAM39150.1 - 8.8e-18 64.3 0.0 1e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Myotub-related PF06602.14 GAM39151.1 - 4e-153 509.5 0.0 4.9e-153 509.2 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Ribosomal_S3_C PF00189.20 GAM39152.1 - 9.6e-25 86.9 0.2 5.1e-24 84.6 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 GAM39152.1 - 6.6e-12 45.1 0.1 1.2e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 GAM39152.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 GAM39152.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Coilin N-terminus tRNA_synthFbeta PF17759.1 GAM39153.1 - 3.4e-50 170.5 0.0 5.1e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 GAM39153.1 - 6.6e-33 112.8 0.6 4.3e-31 107.0 0.1 2.5 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 GAM39153.1 - 7.8e-23 81.0 0.0 1.9e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 GAM39153.1 - 2.7e-18 66.0 0.0 2.2e-15 56.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.17 GAM39153.1 - 0.0085 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus VP23 like capsid protein DUF2740 PF10872.8 GAM39153.1 - 0.058 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) HEAT PF02985.22 GAM39154.1 - 3.6e-41 135.6 11.8 0.015 15.5 0.1 13.4 13 0 0 13 13 13 11 HEAT repeat HEAT_2 PF13646.6 GAM39154.1 - 1.5e-37 127.9 3.4 9.3e-11 42.0 0.0 8.5 3 3 4 8 8 8 6 HEAT repeats HEAT_EZ PF13513.6 GAM39154.1 - 5.2e-16 58.8 4.0 0.014 15.9 0.0 8.3 8 2 2 10 10 9 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAM39154.1 - 6.1e-13 49.2 4.8 0.00093 19.7 0.1 7.8 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAM39154.1 - 1.2e-10 41.6 12.0 0.0012 19.0 0.1 6.0 4 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAM39154.1 - 7.9e-08 31.3 8.8 1.1e-06 27.5 2.1 3.6 2 1 2 4 4 4 2 Adaptin N terminal region RTP1_C1 PF10363.9 GAM39154.1 - 5.7e-07 29.7 5.6 0.14 12.3 0.1 5.0 4 1 1 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 GAM39154.1 - 0.00079 19.1 1.8 0.45 10.0 0.1 4.6 2 2 2 5 5 5 1 CLASP N terminal Proteasom_PSMB PF10508.9 GAM39154.1 - 0.0047 15.5 5.5 0.42 9.0 0.0 2.9 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit Arm PF00514.23 GAM39154.1 - 0.019 15.0 7.9 3.1 8.0 0.0 5.8 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat IFRD PF05004.13 GAM39154.1 - 0.033 13.3 0.7 1.9 7.5 0.0 3.6 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) CARD_2 PF16739.5 GAM39154.1 - 0.037 14.0 0.4 8.5 6.4 0.0 3.3 3 0 0 3 3 3 0 Caspase recruitment domain M11L PF11099.8 GAM39154.1 - 0.057 13.7 0.8 36 4.6 0.0 3.8 2 1 1 3 3 3 0 Apoptosis regulator M11L like Ecm29 PF13001.7 GAM39154.1 - 0.45 9.1 4.3 2.4 6.7 0.2 3.2 3 1 1 4 4 4 0 Proteasome stabiliser DRIM PF07539.12 GAM39154.1 - 1.3 7.3 6.5 1.2 7.3 0.7 3.1 2 1 0 4 4 4 0 Down-regulated in metastasis Glyco_transf_90 PF05686.12 GAM39156.1 - 4.7e-13 48.8 4.6 5.5e-10 38.7 3.6 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 90 Abhydrolase_1 PF00561.20 GAM39156.1 - 6.3e-12 45.7 0.2 3.4e-10 40.0 0.0 2.8 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM39156.1 - 2.9e-11 44.4 0.0 2.7e-10 41.2 0.0 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ferric_reduct PF01794.19 GAM39156.1 - 6.3e-11 42.5 5.7 2.3e-10 40.7 5.7 2.1 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Hydrolase_4 PF12146.8 GAM39156.1 - 7.5e-07 28.7 0.0 1.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 GAM39156.1 - 0.042 14.2 0.5 0.16 12.3 0.5 2.1 1 0 0 1 1 1 0 Epoxide hydrolase N terminus ABC_cobalt PF09819.9 GAM39156.1 - 0.24 11.6 0.0 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 ABC-type cobalt transport system, permease component DUF2104 PF09877.9 GAM39156.1 - 0.32 11.3 1.7 0.79 10.0 1.7 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) adh_short PF00106.25 GAM39157.1 - 3.8e-18 65.7 0.0 1.1e-15 57.7 0.0 2.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM39157.1 - 7.2e-08 32.3 0.0 5.8e-07 29.3 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM39157.1 - 1.5e-06 28.3 0.0 2.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM39157.1 - 0.11 12.0 0.0 1.2 8.5 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family tRNA_U5-meth_tr PF05958.11 GAM39157.1 - 0.26 10.2 0.0 0.88 8.5 0.0 1.7 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase Glyco_transf_8 PF01501.20 GAM39158.1 - 6.2e-22 78.4 0.1 5.1e-21 75.4 0.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Prok-E2_E PF14462.6 GAM39158.1 - 0.0013 18.6 0.5 0.046 13.5 0.0 2.7 2 0 0 2 2 2 1 Prokaryotic E2 family E Nucleotid_trans PF03407.16 GAM39158.1 - 0.0029 17.6 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase CDO_I PF05995.12 GAM39159.1 - 7.4e-45 152.3 0.0 9.5e-45 151.9 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 GAM39159.1 - 0.013 15.0 0.1 0.029 13.8 0.1 1.5 1 1 0 1 1 1 0 PCO_ADO MMR_HSR1_Xtn PF16897.5 GAM39160.1 - 3.6e-40 136.3 1.2 1.2e-39 134.6 0.2 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 GAM39160.1 - 3.9e-23 81.3 0.1 9.9e-23 80.0 0.1 1.8 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 GAM39160.1 - 2.3e-21 76.0 0.1 6.5e-21 74.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM39160.1 - 1.1e-09 38.1 0.1 4.4e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAM39160.1 - 0.00016 21.3 0.1 3.3 7.2 0.0 4.0 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 GAM39160.1 - 0.00034 20.7 0.1 0.073 13.1 0.0 2.4 1 1 1 2 2 2 1 Dynamin family MeaB PF03308.16 GAM39160.1 - 0.0069 15.4 0.1 0.019 13.9 0.1 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 GAM39160.1 - 0.024 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Arf PF00025.21 GAM39160.1 - 0.097 12.1 0.1 3 7.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAM39160.1 - 0.3 11.0 1.6 4.5 7.2 0.0 2.8 4 0 0 4 4 4 0 RsgA GTPase HTH_Tnp_Tc5 PF03221.16 GAM39161.1 - 1.9e-14 53.4 0.1 3.7e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 GAM39161.1 - 6.2e-06 25.7 0.1 1.3e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 GAM39161.1 - 0.00054 19.7 0.1 0.00097 18.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 GAM39161.1 - 0.041 13.6 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.22 GAM39161.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 GAM39161.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_10 PF04967.12 GAM39161.1 - 0.13 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain PXA PF02194.15 GAM39162.1 - 2.8e-41 141.5 0.5 4.5e-41 140.8 0.5 1.3 1 0 0 1 1 1 1 PXA domain PUL PF08324.11 GAM39162.1 - 0.092 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 PUL domain IU_nuc_hydro PF01156.19 GAM39163.1 - 1.6e-74 251.3 0.0 2.5e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Vac_ImportDeg PF09783.9 GAM39163.1 - 4.8e-21 75.2 0.1 1.2e-20 73.9 0.1 1.6 2 0 0 2 2 2 1 Vacuolar import and degradation protein Atrophin-1 PF03154.15 GAM39163.1 - 9.9e-05 20.8 10.2 0.00018 20.0 10.2 1.3 1 0 0 1 1 1 1 Atrophin-1 family DUF3915 PF13054.6 GAM39163.1 - 0.88 9.6 5.1 1.7 8.6 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Ribosomal_L7Ae PF01248.26 GAM39164.1 - 4e-24 84.2 0.0 5.1e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 GAM39164.1 - 0.054 13.4 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF1846 PF08903.11 GAM39164.1 - 0.12 10.9 0.0 0.13 10.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Ank_2 PF12796.7 GAM39165.1 - 1.6e-19 70.3 0.1 2.1e-11 44.2 0.1 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM39165.1 - 2e-17 63.0 1.9 5.8e-07 29.7 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM39165.1 - 1.1e-14 54.5 0.1 1.1e-07 32.2 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM39165.1 - 1.4e-12 47.4 0.7 0.0027 18.1 0.1 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 GAM39165.1 - 5.1e-10 38.7 1.5 0.036 14.6 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat 2OG-FeII_Oxy_2 PF13532.6 GAM39166.1 - 9.6e-13 48.8 0.0 8.2e-12 45.7 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rotamase_3 PF13616.6 GAM39167.1 - 1.6e-15 57.6 0.1 3.1e-15 56.7 0.1 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 GAM39167.1 - 2.8e-13 50.6 0.0 4.7e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 GAM39167.1 - 0.002 19.0 0.1 0.0055 17.5 0.0 1.7 1 1 1 2 2 2 1 PPIC-type PPIASE domain DUF3970 PF13113.6 GAM39167.1 - 0.2 11.9 1.0 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) Stathmin PF00836.19 GAM39168.1 - 0.00032 20.7 0.1 0.00045 20.2 0.1 1.2 1 0 0 1 1 1 1 Stathmin family CSRNP_N PF16019.5 GAM39168.1 - 0.08 12.8 1.9 0.12 12.3 1.9 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus LOH1CR12 PF10158.9 GAM39168.1 - 0.12 12.4 4.2 0.11 12.5 2.9 1.6 2 0 0 2 2 2 0 Tumour suppressor protein DUF4303 PF14136.6 GAM39168.1 - 0.13 12.0 0.3 0.23 11.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) Vac_Fusion PF02346.16 GAM39168.1 - 0.35 10.5 3.3 9.9 5.9 1.6 2.8 1 1 1 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 CLZ PF16526.5 GAM39168.1 - 1.1 9.7 6.5 4.3 7.8 2.8 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SLS PF14611.6 GAM39169.1 - 2.3e-25 89.7 1.0 3.5e-25 89.1 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator A_deamin PF02137.18 GAM39169.1 - 5.7e-22 78.6 0.0 1.1e-21 77.7 0.0 1.4 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dCMP_cyt_deam_1 PF00383.23 GAM39169.1 - 0.23 11.4 2.7 0.85 9.5 2.7 1.9 1 1 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region SF3b10 PF07189.11 GAM39170.1 - 5.3e-35 119.4 0.0 5.9e-35 119.2 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF3074 PF11274.8 GAM39171.1 - 2.4e-55 187.4 0.0 6.4e-55 186.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) START PF01852.19 GAM39171.1 - 0.0018 17.7 0.0 0.33 10.3 0.0 2.5 2 0 0 2 2 2 1 START domain CALCOCO1 PF07888.11 GAM39171.1 - 0.019 13.9 23.0 0.032 13.1 23.0 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HALZ PF02183.18 GAM39171.1 - 0.027 14.7 8.0 0.065 13.5 0.6 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper APG6_N PF17675.1 GAM39171.1 - 0.08 13.5 28.2 0.84 10.2 9.1 3.7 1 1 2 3 3 3 0 Apg6 coiled-coil region Fez1 PF06818.15 GAM39171.1 - 0.24 11.8 18.8 0.6 10.5 18.8 1.7 1 0 0 1 1 1 0 Fez1 Uds1 PF15456.6 GAM39171.1 - 0.64 10.2 17.0 4.1 7.6 1.2 2.8 2 0 0 2 2 2 0 Up-regulated During Septation SKA2 PF16740.5 GAM39171.1 - 1.7 8.5 12.3 0.25 11.1 4.9 2.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 CortBP2 PF09727.9 GAM39171.1 - 2.5 8.0 20.2 1.2 9.0 17.6 1.8 1 1 0 1 1 1 0 Cortactin-binding protein-2 YabA PF06156.13 GAM39171.1 - 9.6 6.9 11.9 0.78 10.4 1.2 3.1 1 1 2 3 3 3 0 Initiation control protein YabA PUCC PF03209.15 GAM39173.1 - 0.0008 18.5 6.1 0.0011 18.1 6.1 1.2 1 0 0 1 1 1 1 PUCC protein Sugar_tr PF00083.24 GAM39173.1 - 0.14 11.0 10.4 0.51 9.1 10.8 1.6 1 1 1 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.16 GAM39173.1 - 0.15 11.0 18.6 0.017 14.1 12.4 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily MFS_1 PF07690.16 GAM39174.1 - 5.2e-32 111.1 52.5 1.6e-31 109.6 52.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM39174.1 - 3.1e-16 58.9 13.0 5.5e-16 58.1 13.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM39174.1 - 6.7e-08 31.8 37.1 1.1e-06 27.8 6.4 3.9 4 1 1 5 5 5 3 Sugar (and other) transporter Putative_PNPOx PF01243.20 GAM39175.1 - 1.4e-06 28.4 0.0 3.4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Sugar_tr PF00083.24 GAM39176.1 - 6.5e-87 292.3 25.2 2.5e-78 264.0 13.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM39176.1 - 1.1e-16 60.7 38.0 5.9e-08 32.0 0.1 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Ribosomal_L27_C PF18471.1 GAM39177.1 - 0.012 15.0 10.6 2.3 7.6 0.4 4.5 3 1 0 4 4 4 0 Ribosomal L27 protein C-terminal domain Gag_p15 PF08723.10 GAM39177.1 - 0.016 15.4 0.2 20 5.4 0.1 4.0 3 1 2 5 5 5 0 Gag protein p15 BRCT PF00533.26 GAM39177.1 - 0.091 13.2 0.3 9.8 6.6 0.2 3.5 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain RET_CLD4 PF17813.1 GAM39177.1 - 0.22 11.8 0.3 2.8 8.3 0.0 2.9 3 0 0 3 3 3 0 RET Cadherin like domain 4 YfdX PF10938.8 GAM39177.1 - 0.25 11.3 12.0 1.1 9.1 5.0 3.8 1 1 2 3 3 3 0 YfdX protein E3_UbLigase_R4 PF13764.6 GAM39177.1 - 2.3 6.3 7.8 0.87 7.7 3.0 2.3 1 1 2 3 3 3 0 E3 ubiquitin-protein ligase UBR4 Cnd1 PF12717.7 GAM39177.1 - 3.8 7.5 8.5 3.8 7.5 0.3 3.4 2 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF1631 PF07793.11 GAM39177.1 - 5.4 5.3 8.3 11 4.3 8.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) SPX PF03105.19 GAM39177.1 - 6.5 6.6 5.4 10 5.9 5.4 1.2 1 0 0 1 1 1 0 SPX domain cwf21 PF08312.12 GAM39178.1 - 0.0042 17.2 1.9 1.3 9.3 1.6 2.3 2 0 0 2 2 2 2 cwf21 domain Cep57_CLD PF14073.6 GAM39178.1 - 0.014 15.4 3.0 0.018 15.1 3.0 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 T3SSipB PF16535.5 GAM39178.1 - 0.021 15.3 0.8 0.028 14.9 0.8 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB Histone_HNS PF00816.21 GAM39178.1 - 0.096 13.5 4.6 0.13 13.1 4.6 1.2 1 0 0 1 1 1 0 H-NS histone family NT-C2 PF10358.9 GAM39179.1 - 4e-31 107.7 0.0 6.1e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins ERG4_ERG24 PF01222.17 GAM39180.1 - 3.6e-152 507.1 3.0 4.1e-152 506.9 3.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 GAM39180.1 - 0.00024 20.7 0.6 0.00065 19.3 0.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ATG27 PF09451.10 GAM39181.1 - 1.1e-12 48.4 0.0 9.4e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 GAM39181.1 - 5.5e-12 45.3 0.0 1.4e-11 44.0 0.0 1.6 2 0 0 2 2 2 1 Mannose-6-phosphate receptor CIMR PF00878.18 GAM39181.1 - 7.5e-09 35.8 1.0 0.002 18.2 0.2 2.5 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Fungal_trans PF04082.18 GAM39182.1 - 1.3e-23 83.4 0.0 3e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM39182.1 - 1.6e-09 37.8 12.5 2.5e-09 37.1 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 GAM39183.1 - 1.4e-29 102.9 0.0 3.5e-29 101.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM39183.1 - 3.3e-18 66.1 0.0 4.7e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM39183.1 - 2.3e-12 47.2 0.0 3.9e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 GAM39183.1 - 0.004 16.6 0.0 0.0053 16.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAM39183.1 - 0.027 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein EBP PF05241.12 GAM39184.1 - 0.17 11.3 7.7 0.061 12.8 3.0 2.2 2 1 0 3 3 3 0 Emopamil binding protein bZIP_1 PF00170.21 GAM39185.1 - 0.0016 18.5 13.1 0.013 15.5 13.1 2.1 1 1 0 1 1 1 1 bZIP transcription factor ABC_tran_Xtn PF12848.7 GAM39185.1 - 0.58 10.2 9.3 1 9.4 9.3 1.3 1 0 0 1 1 1 0 ABC transporter MFS_1 PF07690.16 GAM39186.1 - 2.8e-27 95.6 31.6 7.1e-21 74.5 10.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM39186.1 - 1e-19 70.8 21.9 7.9e-19 67.8 21.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Spore_YtrH PF14034.6 GAM39186.1 - 0.0091 16.1 5.0 0.12 12.5 0.4 2.8 2 1 0 2 2 2 2 Sporulation protein YtrH Glyco_hydro_3_C PF01915.22 GAM39187.1 - 1.1e-53 182.3 0.0 2.3e-53 181.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAM39187.1 - 4e-39 134.8 0.0 6.4e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM39187.1 - 5.3e-16 58.5 0.1 9.8e-16 57.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Scs3p PF10261.9 GAM39188.1 - 1.2e-66 224.8 6.8 2.7e-66 223.6 6.8 1.5 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Fungal_trans PF04082.18 GAM39189.1 - 2.1e-17 63.0 0.1 4e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 GAM39190.1 - 3.1e-33 115.2 52.1 3.1e-33 115.2 52.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM39190.1 - 8.4e-13 48.0 7.3 8.4e-13 48.0 7.3 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter Cytochrom_B558a PF05038.13 GAM39190.1 - 0.03 13.9 2.2 0.77 9.3 0.3 2.7 2 1 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit DUF2721 PF11026.8 GAM39190.1 - 8.2 6.3 21.5 0.39 10.6 1.6 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2721) Erythro_esteras PF05139.14 GAM39192.1 - 9.4e-127 423.5 1.5 1.1e-126 423.3 1.5 1.0 1 0 0 1 1 1 1 Erythromycin esterase Cofac_haem_bdg PF04187.13 GAM39192.1 - 0.0032 17.5 0.1 0.98 9.4 0.0 2.2 2 0 0 2 2 2 2 Haem-binding uptake, Tiki superfamily, ChaN Flagellar_rod PF05149.12 GAM39192.1 - 0.12 11.8 0.8 0.18 11.2 0.8 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein NUP50 PF08911.11 GAM39193.1 - 0.8 10.4 9.4 0.18 12.5 1.1 3.8 3 1 0 3 3 3 0 NUP50 (Nucleoporin 50 kDa) DUF3535 PF12054.8 GAM39194.1 - 1.9e-129 432.7 0.0 4.1e-128 428.3 0.0 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 GAM39194.1 - 9.7e-63 212.0 0.0 2.3e-62 210.8 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM39194.1 - 1.6e-19 70.3 0.0 4.1e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 GAM39194.1 - 2.6e-12 45.9 18.3 0.31 11.4 0.3 10.3 12 0 0 12 12 11 4 HEAT repeat HEAT_2 PF13646.6 GAM39194.1 - 1.1e-07 32.2 11.8 0.0024 18.2 0.2 6.9 5 1 1 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.7 GAM39194.1 - 8.9e-07 29.4 0.2 0.026 15.1 0.1 3.9 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAM39194.1 - 9.6e-05 22.5 0.4 0.065 13.3 0.0 4.6 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 GAM39194.1 - 0.0009 19.5 0.4 0.86 10.0 0.0 5.1 6 0 0 6 6 6 1 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 GAM39194.1 - 0.012 15.2 0.2 1 8.9 0.0 3.3 2 1 1 3 3 3 0 CLASP N terminal HEAT_EZ PF13513.6 GAM39194.1 - 0.048 14.2 17.1 1.6 9.3 0.1 7.3 8 0 0 8 8 8 0 HEAT-like repeat ERCC3_RAD25_C PF16203.5 GAM39194.1 - 0.065 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Ndufs5 PF10200.9 GAM39195.1 - 1e-05 25.7 0.0 1.3e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 GAM39195.1 - 0.094 13.1 1.1 0.54 10.7 1.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) CHCH PF06747.13 GAM39195.1 - 0.098 12.8 1.2 0.16 12.2 1.2 1.4 1 0 0 1 1 1 0 CHCH domain Sec39 PF08314.11 GAM39196.1 - 3.4e-262 872.3 2.0 4.3e-262 871.9 2.0 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Pkinase PF00069.25 GAM39197.1 - 9.9e-66 221.8 0.0 1.2e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM39197.1 - 1.4e-36 126.1 0.0 2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM39197.1 - 2e-07 30.6 0.0 3.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAM39197.1 - 7.7e-05 21.6 0.0 0.00012 21.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 GAM39197.1 - 0.016 14.8 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 GAM39197.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 GAM39197.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 TPR_1 PF00515.28 GAM39200.1 - 9.6e-44 145.5 13.5 1.9e-07 30.6 0.2 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAM39200.1 - 3.6e-40 132.8 13.5 1.5e-06 27.9 0.2 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat DUF4451 PF14616.6 GAM39200.1 - 2.9e-25 88.8 0.0 5.7e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DnaJ PF00226.31 GAM39200.1 - 5.6e-24 84.0 4.5 1.1e-23 83.1 1.7 2.9 3 0 0 3 3 2 1 DnaJ domain TPR_19 PF14559.6 GAM39200.1 - 4e-22 78.5 16.3 2.4e-05 24.8 0.1 5.7 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAM39200.1 - 4.8e-21 73.2 8.7 8.8e-05 22.4 0.1 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAM39200.1 - 9.9e-21 73.2 19.3 1.1e-09 37.8 0.5 7.0 4 3 3 7 7 7 6 TPR repeat TPR_16 PF13432.6 GAM39200.1 - 1.6e-20 73.5 11.4 0.00015 22.4 0.1 5.4 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAM39200.1 - 9.7e-20 69.6 12.4 0.00019 21.9 0.1 7.8 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAM39200.1 - 1.9e-17 62.3 14.6 0.00053 20.2 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAM39200.1 - 4.1e-15 54.6 8.5 0.073 13.1 0.2 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 GAM39200.1 - 6.8e-15 55.1 11.6 0.0004 20.6 0.7 6.0 3 2 1 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM39200.1 - 1.6e-12 47.4 6.6 0.0011 19.2 0.0 4.7 2 2 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 GAM39200.1 - 3.3e-12 46.3 9.2 0.00066 19.7 0.2 5.1 4 1 1 5 5 5 4 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 GAM39200.1 - 6.6e-10 38.7 7.8 0.017 14.3 0.1 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAM39200.1 - 2.2e-09 37.3 12.0 0.046 14.4 0.3 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM39200.1 - 8.9e-08 32.2 6.7 0.31 11.2 0.0 4.8 3 2 2 5 5 5 3 Tetratricopeptide repeat BTAD PF03704.17 GAM39200.1 - 2.1e-05 25.0 4.7 0.088 13.2 0.0 4.1 3 1 0 4 4 4 2 Bacterial transcriptional activator domain TPR_10 PF13374.6 GAM39200.1 - 0.00035 20.3 16.6 9.4 6.3 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat ChAPs PF09295.10 GAM39200.1 - 0.003 16.6 0.4 0.29 10.1 0.1 2.3 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) SHNi-TPR PF10516.9 GAM39200.1 - 0.019 14.4 8.3 9.2 5.8 0.4 4.9 5 0 0 5 5 5 0 SHNi-TPR MIT PF04212.18 GAM39200.1 - 0.024 14.7 10.5 3.1 7.9 0.1 4.6 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain Coatomer_E PF04733.14 GAM39200.1 - 0.035 13.5 0.8 3.6 6.9 0.1 2.8 3 0 0 3 3 3 0 Coatomer epsilon subunit Alkyl_sulf_dimr PF14863.6 GAM39200.1 - 0.058 13.8 6.0 39 4.7 0.3 4.6 2 2 2 4 4 4 0 Alkyl sulfatase dimerisation TPR_20 PF14561.6 GAM39200.1 - 0.19 12.1 12.0 3.9 7.9 0.5 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF627 PF04781.12 GAM39200.1 - 0.27 11.2 1.4 0.87 9.6 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_4 PF07721.14 GAM39200.1 - 0.31 11.8 10.3 5.1 8.0 0.1 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat Sugar_tr PF00083.24 GAM39201.1 - 1.9e-83 280.9 32.8 2.2e-83 280.6 32.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM39201.1 - 5.9e-16 58.3 38.1 1.2e-11 44.1 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 GAM39201.1 - 0.052 13.9 4.9 2.4 8.5 0.1 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) LMBR1 PF04791.16 GAM39203.1 - 0.4 9.5 1.2 0.52 9.2 1.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Pkinase PF00069.25 GAM39204.1 - 6.6e-40 137.1 0.0 1.2e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM39204.1 - 1.3e-27 96.8 0.0 1.9e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM39204.1 - 0.002 17.5 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM39204.1 - 0.051 12.9 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Med10 PF09748.9 GAM39205.1 - 1.4e-42 144.5 0.1 1.7e-42 144.2 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 GAM39205.1 - 0.038 13.9 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) p450 PF00067.22 GAM39208.1 - 5.4e-74 249.6 0.0 7e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro_CA PF00484.19 GAM39209.1 - 3.4e-12 46.9 1.7 5.5e-11 43.0 1.7 2.0 1 1 0 1 1 1 1 Carbonic anhydrase Peptidase_M28 PF04389.17 GAM39210.1 - 6.9e-35 120.5 0.0 1.1e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 GAM39210.1 - 0.018 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 F-box-like PF12937.7 GAM39211.1 - 1e-12 47.7 0.3 3.2e-12 46.1 0.3 2.0 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 GAM39211.1 - 1.7e-09 36.9 8.1 0.5 10.6 0.0 9.5 11 0 0 11 11 11 2 Leucine Rich repeat LRR_4 PF12799.7 GAM39211.1 - 3.2e-09 36.9 8.3 0.65 10.5 0.0 6.2 3 2 2 6 6 6 4 Leucine Rich repeats (2 copies) F-box PF00646.33 GAM39211.1 - 1.8e-05 24.5 3.0 2.7e-05 23.9 1.0 2.4 2 0 0 2 2 2 1 F-box domain DUF1699 PF08004.11 GAM39211.1 - 0.0024 17.6 0.7 0.14 11.8 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1699) LRR_8 PF13855.6 GAM39211.1 - 0.016 14.9 4.8 0.27 11.0 0.1 4.4 5 1 0 5 5 5 0 Leucine rich repeat Preseq_ALAS PF09029.10 GAM39211.1 - 0.74 10.3 0.0 0.74 10.3 0.0 2.9 3 0 0 3 3 3 0 5-aminolevulinate synthase presequence AMP-binding PF00501.28 GAM39212.1 - 1.6e-70 237.9 0.0 1.9e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM39212.1 - 1.7e-19 70.6 0.1 3.5e-19 69.6 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LysR_substrate PF03466.20 GAM39212.1 - 0.071 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 LysR substrate binding domain Ribosomal_L13 PF00572.18 GAM39213.1 - 5.5e-11 42.8 0.1 6.6e-09 36.1 0.0 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 DnaJ PF00226.31 GAM39214.1 - 7.3e-21 74.1 0.3 1.9e-20 72.7 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain Adaptin_N PF01602.20 GAM39215.1 - 1.5e-142 475.9 0.9 1.7e-142 475.7 0.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 GAM39215.1 - 8.5e-20 71.1 0.0 1.8e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 GAM39215.1 - 1.8e-07 31.3 8.2 0.00014 21.9 0.0 4.6 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM39215.1 - 3.3e-05 24.2 2.7 0.77 10.2 0.0 4.8 5 1 0 5 5 5 2 HEAT repeats HEAT PF02985.22 GAM39215.1 - 0.039 14.2 1.6 20 5.8 0.1 4.6 3 0 0 3 3 3 0 HEAT repeat Arm PF00514.23 GAM39215.1 - 0.042 13.9 0.9 1.3e+02 2.8 0.1 5.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat MBOAT PF03062.19 GAM39216.1 - 1.4e-35 123.3 29.0 2e-34 119.5 29.0 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MLANA PF14991.6 GAM39216.1 - 0.25 11.6 0.3 1.5 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein melan-A EamA PF00892.20 GAM39217.1 - 1.6e-11 44.5 23.9 7.2e-06 26.2 4.2 2.6 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 GAM39217.1 - 2.4e-08 33.5 0.7 2.4e-08 33.5 0.7 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 GAM39217.1 - 8.5e-06 25.2 6.0 8.5e-06 25.2 6.0 1.7 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.16 GAM39217.1 - 0.00039 19.9 7.0 0.0004 19.8 0.6 2.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family Trp_oprn_chp PF09534.10 GAM39217.1 - 0.25 11.1 2.5 2.6 7.8 1.2 2.5 1 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TrbC PF04956.13 GAM39217.1 - 0.79 10.0 7.4 19 5.5 3.8 3.1 2 0 0 2 2 2 0 TrbC/VIRB2 family PDR_assoc PF08370.11 GAM39217.1 - 1.2 8.9 5.7 0.23 11.2 0.5 2.3 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Tetraspanin PF00335.20 GAM39217.1 - 1.7 8.3 7.5 1.7 8.3 1.6 2.8 2 0 0 2 2 2 0 Tetraspanin family CRT-like PF08627.10 GAM39217.1 - 2.2 7.2 14.9 0.51 9.2 5.4 3.3 3 1 0 3 3 3 0 CRT-like, chloroquine-resistance transporter-like Phage_holin_3_6 PF07332.11 GAM39217.1 - 3.9 7.5 19.5 0.075 13.1 2.0 3.9 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Med15_fungi PF05397.12 GAM39218.1 - 5.7e-31 107.1 3.2 5.7e-31 107.1 3.2 5.1 5 0 0 5 5 5 1 Mediator complex subunit 15 KIX_2 PF16987.5 GAM39218.1 - 1.4e-09 37.8 0.4 1.4e-09 37.8 0.4 2.6 2 0 0 2 2 2 1 KIX domain KIX PF02172.16 GAM39218.1 - 0.043 14.1 0.5 0.13 12.6 0.5 1.7 1 0 0 1 1 1 0 KIX domain DUF1104 PF06518.11 GAM39218.1 - 8 6.9 6.9 4.2 7.8 0.6 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) LMBR1 PF04791.16 GAM39219.1 - 2.3e-88 297.4 0.0 2.6e-88 297.2 0.0 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein FUSC PF04632.12 GAM39219.1 - 0.0056 15.3 5.6 0.015 13.9 0.5 2.2 2 0 0 2 2 2 2 Fusaric acid resistance protein family DUF3418 PF11898.8 GAM39219.1 - 0.015 14.0 0.5 0.025 13.3 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Globin PF00042.22 GAM39219.1 - 0.2 12.3 0.1 1.4 9.5 0.1 2.2 2 0 0 2 2 2 0 Globin BAG PF02179.16 GAM39220.1 - 1.2e-13 51.3 0.0 2.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 GAM39220.1 - 4e-06 26.5 0.0 6.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Glutaredoxin PF00462.24 GAM39222.1 - 1.3e-19 70.1 0.0 2e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 GAM39222.1 - 0.0056 17.1 0.1 0.0084 16.5 0.1 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.20 GAM39222.1 - 0.013 15.5 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 GAM39222.1 - 0.018 15.5 0.3 0.027 14.9 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.20 GAM39222.1 - 0.084 12.6 0.3 0.82 9.4 0.3 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 GAM39222.1 - 0.093 12.8 0.0 0.21 11.7 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.6 GAM39222.1 - 0.16 12.1 0.1 8.2 6.6 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin Chalcone_2 PF16035.5 GAM39223.1 - 2e-78 262.8 0.0 3.9e-78 261.9 0.0 1.5 1 0 0 1 1 1 1 Chalcone isomerase like MAGE PF01454.19 GAM39223.1 - 4.6e-62 209.5 0.0 8.1e-62 208.7 0.0 1.4 1 0 0 1 1 1 1 MAGE family Glyco_hydro_28 PF00295.17 GAM39224.1 - 2.3e-43 148.5 4.3 1.2e-42 146.1 4.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Bac_rhamnosid6H PF17389.2 GAM39225.1 - 4.9e-16 58.9 3.2 1e-13 51.3 1.5 2.1 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 GAM39225.1 - 1.4e-06 27.9 0.0 3.8e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 GAM39225.1 - 0.0011 18.9 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Cadherin-like PF12733.7 GAM39225.1 - 0.013 16.1 0.2 0.057 14.0 0.2 2.1 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain PALP PF00291.25 GAM39226.1 - 7.1e-58 196.3 0.0 8.6e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HisG_C PF08029.11 GAM39226.1 - 0.034 14.3 0.4 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 HisG, C-terminal domain Ank_3 PF13606.6 GAM39227.1 - 4.6e-09 35.8 0.1 0.0077 16.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 GAM39227.1 - 1.2e-08 35.0 0.2 0.016 15.5 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM39227.1 - 2.3e-07 31.3 0.0 4.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAM39227.1 - 1.9e-06 28.0 0.0 0.015 15.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 GAM39227.1 - 1.5e-05 25.4 0.7 0.0026 18.3 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) PPR_long PF17177.4 GAM39227.1 - 0.0087 15.4 0.1 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP dsRBD2 PF17842.1 GAM39227.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 TFIIS_C PF01096.18 GAM39228.1 - 4.5e-18 64.8 3.3 4.5e-18 64.8 3.3 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 GAM39228.1 - 2.7e-06 27.1 3.1 2.1e-05 24.3 1.0 3.2 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit zf-DNA_Pol PF08996.10 GAM39228.1 - 0.00089 19.1 4.0 0.0057 16.4 0.5 2.0 1 1 1 2 2 2 1 DNA Polymerase alpha zinc finger Zn_Tnp_IS1595 PF12760.7 GAM39228.1 - 0.0013 18.7 5.0 0.011 15.7 1.2 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain IBR PF01485.21 GAM39228.1 - 0.0034 17.6 4.1 0.47 10.7 0.3 2.3 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain PhnA_Zn_Ribbon PF08274.12 GAM39228.1 - 0.014 15.3 5.4 0.096 12.7 0.2 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon C1_4 PF07975.12 GAM39228.1 - 0.023 14.9 4.4 0.14 12.4 0.2 2.5 2 1 0 2 2 2 0 TFIIH C1-like domain C1_1 PF00130.22 GAM39228.1 - 0.031 14.2 1.1 0.33 10.9 0.1 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_recom PF13408.6 GAM39228.1 - 0.037 14.5 0.4 0.31 11.6 0.1 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-DNL PF05180.12 GAM39228.1 - 0.038 13.9 1.0 0.33 10.9 0.2 2.6 2 1 0 2 2 2 0 DNL zinc finger zinc_ribbon_12 PF11331.8 GAM39228.1 - 0.042 13.7 1.9 0.71 9.7 0.7 2.6 2 0 0 2 2 2 0 Probable zinc-ribbon domain Zn_Tnp_IS1 PF03811.13 GAM39228.1 - 0.044 13.5 1.9 0.044 13.5 1.9 2.4 3 0 0 3 3 3 0 InsA N-terminal domain DiS_P_DiS PF06750.13 GAM39228.1 - 0.12 12.5 0.6 0.32 11.1 0.2 1.9 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain NOB1_Zn_bind PF08772.11 GAM39228.1 - 0.18 12.0 4.5 1.8 8.8 0.2 2.6 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-H2C2_2 PF13465.6 GAM39228.1 - 0.58 10.7 12.0 0.81 10.2 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zinc_ribbon_4 PF13717.6 GAM39228.1 - 0.67 9.9 11.4 4 7.4 0.2 3.9 3 1 1 4 4 4 0 zinc-ribbon domain Lar_restr_allev PF14354.6 GAM39228.1 - 0.74 10.2 5.2 5.9 7.4 5.2 2.2 1 1 0 1 1 1 0 Restriction alleviation protein Lar GTP_EFTU PF00009.27 GAM39229.1 - 3.1e-54 183.5 0.0 4.5e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAM39229.1 - 2.2e-41 140.7 0.0 5.4e-41 139.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAM39229.1 - 3e-12 46.8 1.6 5.1e-12 46.0 0.6 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAM39229.1 - 0.00017 21.6 0.2 0.0036 17.4 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 GAM39229.1 - 0.12 12.3 1.8 0.15 12.0 0.4 1.8 2 0 0 2 2 2 0 Elongation factor Tu domain 4 FlpD PF02662.16 GAM39229.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Med31 PF05669.12 GAM39231.1 - 5.5e-30 103.2 0.0 7.6e-30 102.8 0.0 1.2 1 0 0 1 1 1 1 SOH1 Pal1 PF08316.11 GAM39232.1 - 5.8e-43 147.0 1.9 2.5e-41 141.7 1.9 2.8 1 1 0 1 1 1 1 Pal1 cell morphology protein DUF3915 PF13054.6 GAM39232.1 - 9 6.3 9.9 0.88 9.6 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) PHD PF00628.29 GAM39233.1 - 2.1e-11 43.5 7.9 5.6e-11 42.2 7.9 1.8 1 0 0 1 1 1 1 PHD-finger APH PF01636.23 GAM39233.1 - 0.01 15.8 0.1 0.19 11.6 0.1 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family ABC_tran_Xtn PF12848.7 GAM39233.1 - 0.024 14.7 2.5 0.1 12.6 2.5 2.1 1 0 0 1 1 1 0 ABC transporter Fungal_trans_2 PF11951.8 GAM39234.1 - 9.8e-07 27.9 0.0 1.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RR_TM4-6 PF06459.12 GAM39234.1 - 0.88 9.3 8.2 1.5 8.6 8.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Fungal_trans PF04082.18 GAM39235.1 - 9e-29 100.3 0.1 1.9e-28 99.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2OG-FeII_Oxy_3 PF13640.6 GAM39235.1 - 7e-12 46.1 0.1 1.5e-11 45.0 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 GAM39235.1 - 3.3e-11 43.1 12.6 6.2e-11 42.2 12.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 GAM39236.1 - 2.3e-06 27.8 18.1 1.7e-05 25.0 2.0 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM39236.1 - 2.5e-05 24.5 5.6 3.6e-05 24.0 2.6 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAM39236.1 - 0.00013 22.5 1.4 0.00013 22.5 1.4 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAM39236.1 - 0.00015 22.0 0.4 0.00043 20.5 0.4 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 GAM39236.1 - 0.002 18.4 2.9 0.0045 17.3 2.9 1.7 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 GAM39236.1 - 0.013 15.5 1.3 0.027 14.5 1.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 GAM39236.1 - 0.045 14.1 0.4 0.12 12.8 0.4 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type BAF1_ABF1 PF04684.13 GAM39236.1 - 0.94 8.5 18.8 0.13 11.3 7.3 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor FOXP-CC PF16159.5 GAM39236.1 - 7.7 7.2 19.2 0.71 10.5 1.5 4.1 2 1 2 4 4 4 0 FOXP coiled-coil domain Forkhead PF00250.18 GAM39237.1 - 7.4e-36 122.3 1.8 1.3e-35 121.5 1.8 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 GAM39237.1 - 2.3e-07 31.0 0.0 4.7e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain GFO_IDH_MocA PF01408.22 GAM39238.1 - 2.9e-08 34.6 0.2 7.8e-08 33.2 0.2 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold LigB PF02900.18 GAM39238.1 - 0.003 16.7 0.1 0.0051 15.9 0.1 1.3 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DHDPS PF00701.22 GAM39239.1 - 1.6e-34 118.9 0.0 1.2e-24 86.6 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family ADH_N PF08240.12 GAM39240.1 - 2.5e-28 98.1 5.6 4.6e-28 97.3 5.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM39240.1 - 8.3e-17 61.4 0.1 6.2e-16 58.6 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAM39240.1 - 0.00019 20.9 0.3 0.00037 19.9 0.3 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAM39240.1 - 0.13 11.5 0.0 0.74 9.1 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain WD40 PF00400.32 GAM39242.1 - 3.4e-28 97.3 15.3 7.5e-06 26.6 0.1 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 GAM39242.1 - 1.7e-10 40.6 0.7 3e-10 39.8 0.1 1.8 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 GAM39242.1 - 3.4e-06 27.3 0.2 1.1 9.6 0.0 4.8 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 GAM39242.1 - 6e-06 26.0 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAM39242.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 0 F-box PQQ PF01011.21 GAM39242.1 - 0.013 15.4 0.5 14 5.8 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat EB1 PF03271.17 GAM39243.1 - 2.4e-17 62.9 0.7 4.5e-17 62.0 0.7 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif Herpes_UL6 PF01763.16 GAM39243.1 - 0.04 12.4 0.0 0.053 12.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like RTA1 PF04479.13 GAM39245.1 - 4.1e-62 209.5 0.7 7.6e-62 208.6 0.7 1.4 1 0 0 1 1 1 1 RTA1 like protein DUF4233 PF14017.6 GAM39245.1 - 5.9 7.3 10.4 0.77 10.1 2.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4233) ING PF12998.7 GAM39246.1 - 1.6e-06 28.6 0.1 2.9e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 GAM39246.1 - 5.3e-06 26.2 6.4 5.3e-06 26.2 6.4 1.6 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 GAM39246.1 - 0.064 13.5 0.6 0.14 12.5 0.6 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain TENA_THI-4 PF03070.16 GAM39248.1 - 1.4e-11 44.6 0.0 3.9e-10 39.9 0.0 2.5 1 1 0 1 1 1 1 TENA/THI-4/PQQC family P16-Arc PF04699.14 GAM39249.1 - 7.4e-45 153.1 0.0 8.5e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Methyltransf_11 PF08241.12 GAM39250.1 - 4.2e-11 43.3 0.0 1e-10 42.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM39250.1 - 6.3e-10 39.1 0.0 9.3e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM39250.1 - 1.3e-07 32.2 0.0 2.7e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM39250.1 - 5.3e-07 30.2 0.0 1.5e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM39250.1 - 0.00024 20.9 0.0 0.00055 19.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM39250.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Dynactin_p62 PF05502.13 GAM39251.1 - 1.5e-132 442.8 4.6 9.7e-129 430.2 0.0 2.4 2 1 1 3 3 3 2 Dynactin p62 family Ribosomal_S7e PF01251.18 GAM39252.1 - 1.3e-81 272.8 0.2 1.5e-81 272.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Ras PF00071.22 GAM39253.1 - 1.4e-50 171.0 0.1 1.3e-48 164.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 GAM39253.1 - 3.5e-28 98.2 0.0 2.2e-26 92.4 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM39253.1 - 7e-09 35.4 0.0 2.6e-08 33.5 0.0 2.0 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM39253.1 - 1.8e-05 24.4 0.0 2.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Acetate_kinase PF00871.17 GAM39254.1 - 3.5e-96 322.3 0.0 4.2e-96 322.0 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family XFP_N PF09364.10 GAM39255.1 - 4.3e-151 502.8 0.0 5.7e-151 502.5 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 GAM39255.1 - 2e-78 262.5 0.0 3e-78 261.9 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 GAM39255.1 - 1.2e-74 249.8 0.0 1.8e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 GAM39255.1 - 0.0048 16.7 0.1 0.0092 15.8 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1133 PF06576.11 GAM39255.1 - 0.034 13.5 0.0 0.53 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) FAST_1 PF06743.15 GAM39255.1 - 0.099 12.6 0.3 16 5.6 0.0 2.7 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Transketolase_C PF02780.20 GAM39255.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain Transket_pyr PF02779.24 GAM39255.1 - 0.12 12.0 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain HCO3_cotransp PF00955.21 GAM39256.1 - 1.1e-64 219.2 12.2 5.6e-39 134.3 0.7 2.1 1 1 1 2 2 2 2 HCO3- transporter family SF1-HH PF16275.5 GAM39257.1 - 1.5e-43 147.7 1.1 3.2e-43 146.7 1.1 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 GAM39257.1 - 6.6e-12 44.9 11.1 1.3e-05 25.0 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 GAM39257.1 - 8.6e-08 31.9 0.1 1.6e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 GAM39257.1 - 1.1e-06 28.5 5.5 0.0014 18.6 2.9 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 GAM39257.1 - 0.001 18.9 6.6 0.38 10.6 0.6 3.0 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 GAM39257.1 - 0.0014 18.3 5.0 0.42 10.4 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 GAM39257.1 - 0.014 15.2 0.5 0.014 15.2 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.8 GAM39257.1 - 1 9.7 7.0 75 3.7 5.0 3.3 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G GST_N PF02798.20 GAM39258.1 - 1.2e-15 57.5 0.0 2.1e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAM39258.1 - 1.5e-13 51.0 0.0 2.7e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM39258.1 - 6.2e-12 45.6 0.0 1.4e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM39258.1 - 6.6e-11 42.3 0.0 1.7e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM39258.1 - 8.2e-11 42.0 0.0 1.3e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM39258.1 - 5e-08 32.9 0.0 9.9e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ferric_reduct PF01794.19 GAM39259.1 - 1.8e-20 73.3 11.2 1.8e-20 73.3 11.2 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAM39259.1 - 2.1e-19 70.2 0.0 3.9e-17 62.8 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAM39259.1 - 2.5e-13 50.1 0.0 1.6e-11 44.2 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 GAM39259.1 - 0.018 15.7 0.0 0.13 13.0 0.0 2.4 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF5134 PF17197.4 GAM39259.1 - 0.1 12.5 4.9 0.36 10.7 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) MBF2 PF15868.5 GAM39259.1 - 0.12 12.9 1.2 1.2 9.7 0.5 2.4 2 0 0 2 2 2 0 Transcription activator MBF2 LEA_6 PF10714.9 GAM39259.1 - 0.29 11.2 4.7 0.48 10.5 2.8 2.1 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 SdpI PF13630.6 GAM39259.1 - 2.2 8.5 5.2 14 5.9 5.2 2.5 1 1 0 1 1 1 0 SdpI/YhfL protein family SR-25 PF10500.9 GAM39260.1 - 1.2 8.7 15.0 0.19 11.3 6.7 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DJ-1_PfpI PF01965.24 GAM39261.1 - 1.2e-11 44.7 0.0 2.1e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 GAM39261.1 - 0.0016 18.2 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like GATase_5 PF13507.6 GAM39261.1 - 0.0023 17.1 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 GAM39261.1 - 0.085 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family CLU PF13236.6 GAM39262.1 - 1.3e-74 250.8 0.0 2.2e-74 250.0 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 GAM39262.1 - 8.7e-56 188.7 0.3 3.9e-55 186.6 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 GAM39262.1 - 2.8e-26 91.6 8.5 8.6e-13 48.4 0.2 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 GAM39262.1 - 7.1e-25 87.2 0.5 1.9e-24 85.8 0.3 1.9 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 GAM39262.1 - 2.9e-23 81.0 2.7 3.4e-06 26.8 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM39262.1 - 0.00043 20.2 3.4 0.38 11.0 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF727 PF05303.12 GAM39262.1 - 0.0022 18.0 0.0 0.0063 16.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 GAM39262.1 - 0.0051 16.9 5.4 0.089 13.1 0.5 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM39262.1 - 0.63 10.6 5.4 2.5e+02 2.4 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat BRF1 PF07741.13 GAM39262.1 - 5.3 7.4 9.0 15 6.0 3.3 2.9 2 0 0 2 2 2 0 Brf1-like TBP-binding domain AAA_16 PF13191.6 GAM39263.1 - 1.3e-08 35.4 0.1 3.6e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 GAM39263.1 - 0.0028 17.3 0.5 0.014 15.0 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAM39263.1 - 0.016 15.2 0.1 0.089 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 GAM39263.1 - 0.018 14.7 0.0 0.038 13.6 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 GAM39263.1 - 0.018 15.0 0.0 0.38 10.7 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 GAM39263.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region CbiA PF01656.23 GAM39263.1 - 0.029 14.4 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2193 PF09959.9 GAM39263.1 - 0.041 12.4 0.0 0.055 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) AAA_22 PF13401.6 GAM39263.1 - 0.041 14.1 0.2 0.11 12.7 0.2 1.7 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.15 GAM39263.1 - 0.043 13.1 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA PF00004.29 GAM39263.1 - 0.06 13.8 0.1 0.14 12.6 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2914 PF11141.8 GAM39263.1 - 0.082 12.7 0.5 0.28 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) AAA_29 PF13555.6 GAM39263.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RTA1 PF04479.13 GAM39265.1 - 7.3e-73 244.6 11.8 7.3e-73 244.6 11.8 1.4 2 0 0 2 2 2 1 RTA1 like protein DEAD PF00270.29 GAM39266.1 - 1.6e-41 142.0 0.0 5.1e-41 140.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM39266.1 - 3.6e-31 107.8 0.0 1.5e-30 105.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM39266.1 - 2.1e-06 27.8 0.0 3.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 GAM39266.1 - 0.054 13.2 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase SNF2_N PF00176.23 GAM39266.1 - 0.15 10.7 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain SCIMP PF15050.6 GAM39267.1 - 0.54 10.7 3.0 1.8 9.0 3.0 1.9 1 0 0 1 1 1 0 SCIMP protein Stm1_N PF09598.10 GAM39268.1 - 3.4e-18 66.2 5.3 3.4e-18 66.2 5.3 4.0 3 2 0 3 3 3 1 Stm1 bZIP_1 PF00170.21 GAM39269.1 - 1.2e-05 25.3 9.5 2.6e-05 24.2 9.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAM39269.1 - 0.0033 17.5 9.4 0.011 15.8 9.4 1.9 1 0 0 1 1 1 1 Basic region leucine zipper Mit_KHE1 PF10173.9 GAM39269.1 - 0.11 12.6 0.6 0.16 12.1 0.6 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF4407 PF14362.6 GAM39269.1 - 5.2 6.3 7.2 2.5 7.3 4.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ABC_tran_Xtn PF12848.7 GAM39269.1 - 7.9 6.6 12.4 1.5 8.9 7.7 2.0 2 0 0 2 2 2 0 ABC transporter Pex19 PF04614.12 GAM39270.1 - 6.3e-56 189.9 12.2 8.5e-56 189.5 9.8 2.0 1 1 1 2 2 2 2 Pex19 protein family DUF1631 PF07793.11 GAM39270.1 - 0.0018 16.8 1.1 0.0033 16.0 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) GET2 PF08690.10 GAM39270.1 - 0.63 9.7 21.3 3.9e+02 0.5 21.3 3.1 1 1 0 1 1 1 0 GET complex subunit GET2 Mid2 PF04478.12 GAM39272.1 - 1.4e-05 25.0 4.9 1.4e-05 25.0 4.9 2.6 1 1 0 2 2 2 1 Mid2 like cell wall stress sensor MAP17 PF15807.5 GAM39272.1 - 0.14 12.4 0.3 0.66 10.2 0.0 2.0 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TMEM154 PF15102.6 GAM39272.1 - 0.19 11.6 0.1 0.19 11.6 0.1 3.5 1 1 1 2 2 2 0 TMEM154 protein family Utp14 PF04615.13 GAM39272.1 - 0.49 8.9 7.9 0.55 8.7 7.9 1.1 1 0 0 1 1 1 0 Utp14 protein DUF1702 PF08012.11 GAM39272.1 - 0.63 8.9 2.6 0.94 8.3 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) Y_phosphatase PF00102.27 GAM39273.1 - 4.6e-50 170.4 0.0 2.7e-49 167.9 0.0 1.9 1 1 0 1 1 1 1 Protein-tyrosine phosphatase FAD_binding_3 PF01494.19 GAM39273.1 - 2.4e-10 40.2 0.0 3.8e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain PTPlike_phytase PF14566.6 GAM39273.1 - 0.00079 19.6 0.0 0.0017 18.5 0.0 1.6 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 GAM39273.1 - 0.0025 17.8 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family SE PF08491.10 GAM39273.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase DSPc PF00782.20 GAM39273.1 - 0.043 13.6 0.2 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain VanZ PF04892.12 GAM39274.1 - 3e-07 31.1 1.0 5.1e-07 30.4 1.0 1.3 1 1 0 1 1 1 1 VanZ like family Bromodomain PF00439.25 GAM39275.1 - 1.5e-18 66.6 1.1 1.2e-17 63.7 0.2 3.0 4 0 0 4 4 4 1 Bromodomain Bromo_TP PF07524.13 GAM39275.1 - 8e-08 32.2 0.0 2.3e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated Zn_clus PF00172.18 GAM39275.1 - 7.4e-07 29.2 9.2 1.3e-06 28.4 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAM39275.1 - 6.6e-06 25.2 0.4 1.4e-05 24.1 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bromo_TP_like PF17027.5 GAM39275.1 - 0.12 12.5 0.0 0.38 10.9 0.0 1.8 1 0 0 1 1 1 0 Histone-fold protein zf-RRPl_C4 PF17026.5 GAM39275.1 - 0.3 11.2 5.5 0.17 12.0 1.6 2.3 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type PBP1_TM PF14812.6 GAM39275.1 - 9.6 6.7 14.4 0.12 12.8 5.4 2.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAD_binding_4 PF01565.23 GAM39276.1 - 2.8e-29 101.6 0.2 4.4e-29 101.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM39276.1 - 0.00034 20.7 0.0 0.00069 19.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DNA_ligase_A_M PF01068.21 GAM39278.1 - 8.8e-51 172.5 0.0 3.6e-48 163.9 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAM39278.1 - 1.4e-37 129.6 0.0 3.1e-37 128.5 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 GAM39278.1 - 2.4e-19 69.8 1.5 1.1e-18 67.7 0.0 2.7 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 GAM39278.1 - 0.00034 21.0 0.0 0.0007 19.9 0.0 1.5 1 0 0 1 1 1 1 RNA ligase RINT1_TIP1 PF04437.13 GAM39279.1 - 4e-178 593.4 0.0 7.5e-178 592.5 0.0 1.4 1 0 0 1 1 1 1 RINT-1 / TIP-1 family ISG65-75 PF11727.8 GAM39279.1 - 0.45 9.7 3.1 1.1 8.4 3.1 1.6 1 0 0 1 1 1 0 Invariant surface glycoprotein Pyridoxal_deC PF00282.19 GAM39280.1 - 4.3e-78 262.6 0.0 1.3e-77 261.1 0.0 1.9 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Clathrin PF00637.20 GAM39280.1 - 2.1e-20 73.1 3.0 3e-19 69.3 0.3 3.8 4 0 0 4 4 4 1 Region in Clathrin and VPS Aminotran_5 PF00266.19 GAM39280.1 - 0.00016 20.8 0.0 0.0003 19.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Vps39_1 PF10366.9 GAM39280.1 - 0.00071 19.8 0.7 0.15 12.4 0.2 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Beta_elim_lyase PF01212.21 GAM39280.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase BUD22 PF09073.10 GAM39280.1 - 0.013 14.9 4.2 0.029 13.7 4.2 1.5 1 0 0 1 1 1 0 BUD22 zf-RING_11 PF17123.5 GAM39280.1 - 0.02 14.6 1.4 0.053 13.3 1.4 1.8 1 0 0 1 1 1 0 RING-like zinc finger Myc_N PF01056.18 GAM39280.1 - 0.09 12.7 4.4 0.21 11.5 4.4 1.5 1 0 0 1 1 1 0 Myc amino-terminal region DUF4746 PF15928.5 GAM39280.1 - 0.32 10.4 3.6 0.65 9.4 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) zf-RING_5 PF14634.6 GAM39280.1 - 0.43 10.6 3.2 0.22 11.5 0.7 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 GAM39280.1 - 0.56 10.6 4.5 0.14 12.5 1.0 1.8 2 0 0 2 2 2 0 Ring finger domain RXT2_N PF08595.11 GAM39280.1 - 4.6 7.3 8.2 13 5.7 8.2 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal TRAP_alpha PF03896.16 GAM39280.1 - 5.1 6.2 5.1 9.4 5.3 5.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.6 GAM39280.1 - 9.7 5.8 9.0 12 5.5 6.2 2.4 2 0 0 2 2 2 0 FAM176 family DUF155 PF02582.14 GAM39281.1 - 1.5e-48 165.2 0.0 2.3e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Ribonuclease_T2 PF00445.18 GAM39282.1 - 4.9e-42 144.2 0.9 6.5e-42 143.8 0.0 1.5 2 0 0 2 2 2 1 Ribonuclease T2 family GT-D PF08759.11 GAM39282.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold zf-H2C2_2 PF13465.6 GAM39283.1 - 1.1e-09 38.2 11.3 0.00042 20.6 0.1 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 GAM39283.1 - 6.3e-07 29.5 23.7 0.0046 17.3 6.3 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM39283.1 - 0.00039 21.0 21.0 0.079 13.8 4.8 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 GAM39283.1 - 0.56 10.0 6.1 6.8 6.5 1.6 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type Bunya_G2 PF03563.13 GAM39283.1 - 1.9 7.7 3.7 3.1 7.0 3.7 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_jaz PF12171.8 GAM39283.1 - 6.2 7.2 7.3 47 4.4 3.9 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding ubiquitin PF00240.23 GAM39284.1 - 4.5e-34 116.0 0.6 7.9e-34 115.2 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 GAM39284.1 - 1.2e-26 92.6 2.7 1.2e-26 92.6 2.7 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 GAM39284.1 - 2.6e-16 59.2 0.7 4.9e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAM39284.1 - 2.8e-05 24.5 0.4 0.00013 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAM39284.1 - 0.0011 19.0 0.6 0.0026 17.8 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAM39284.1 - 0.0047 17.2 0.9 0.0079 16.5 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAM39284.1 - 0.0054 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 GAM39284.1 - 0.013 16.1 0.7 0.019 15.6 0.7 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAM39284.1 - 0.021 14.9 1.0 5.9 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain DUF971 PF06155.12 GAM39284.1 - 0.1 13.2 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Glyco_hydro_18 PF00704.28 GAM39285.1 - 4.8e-87 292.6 0.9 5.5e-87 292.4 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Imm10 PF15588.6 GAM39285.1 - 0.17 12.0 0.1 0.38 10.9 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 10 Piwi PF02171.17 GAM39286.1 - 3.6e-67 226.7 0.1 5.8e-67 226.1 0.1 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 GAM39286.1 - 8e-18 65.4 0.1 1.8e-17 64.2 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 GAM39286.1 - 1.6e-11 44.2 0.2 2.9e-11 43.3 0.2 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 GAM39286.1 - 2.6e-11 43.6 0.0 1.1e-10 41.7 0.0 2.1 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL1 PF08699.10 GAM39286.1 - 8.8e-11 41.3 0.0 1.9e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 GAM39286.1 - 7.3e-10 39.0 0.0 1.7e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain p450 PF00067.22 GAM39287.1 - 4.7e-05 22.3 0.0 5.5e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Orbi_VP7 PF00897.17 GAM39287.1 - 0.052 12.5 0.0 0.053 12.5 0.0 1.0 1 0 0 1 1 1 0 Orbivirus inner capsid protein VP7 Metallopep PF12044.8 GAM39288.1 - 1.6e-157 524.5 0.0 2.3e-157 524.0 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 GAM39288.1 - 0.0095 15.9 0.0 0.096 12.6 0.0 2.1 1 1 1 2 2 2 2 Jacalin-like lectin domain CP2 PF04516.15 GAM39289.1 - 2.9e-80 268.9 0.0 4.5e-80 268.3 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor AKNA PF12443.8 GAM39289.1 - 0.09 13.4 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor PUF PF00806.19 GAM39290.1 - 3.2e-19 67.4 0.1 0.019 14.6 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RCC1 PF00415.18 GAM39291.1 - 2.4e-28 98.5 3.9 8.8e-07 29.4 0.0 7.0 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM39291.1 - 3.3e-20 71.4 19.3 1.5e-10 40.6 0.1 7.5 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat DNA_gyraseA_C PF03989.13 GAM39291.1 - 0.039 13.4 0.0 9.7 5.8 0.0 2.8 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller Sec34 PF04136.15 GAM39292.1 - 2.7e-34 118.2 1.8 2.7e-34 118.2 1.8 2.0 3 0 0 3 3 3 1 Sec34-like family Sin3_corepress PF08295.12 GAM39292.1 - 0.17 12.0 0.6 0.55 10.3 0.1 2.1 2 0 0 2 2 2 0 Sin3 family co-repressor Pkinase PF00069.25 GAM39293.1 - 1.3e-58 198.4 0.0 2e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM39293.1 - 4.3e-41 140.9 0.0 6.3e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM39293.1 - 6.4e-10 38.8 0.0 3.5e-06 26.6 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 GAM39293.1 - 0.0031 16.4 0.8 0.0053 15.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAM39293.1 - 0.0085 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM39293.1 - 0.037 14.0 0.0 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family SAM_3 PF18016.1 GAM39293.1 - 0.12 12.2 0.2 0.34 10.7 0.2 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) TPP_enzyme_N PF02776.18 GAM39294.1 - 9.5e-33 113.2 0.0 1.8e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAM39294.1 - 5.1e-22 78.1 0.0 2.2e-20 72.8 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 GAM39294.1 - 8.1e-14 51.7 0.0 1.8e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 GAM39294.1 - 0.13 11.2 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component THUMP PF02926.17 GAM39295.1 - 2.9e-11 43.7 0.2 5.9e-11 42.7 0.2 1.5 1 0 0 1 1 1 1 THUMP domain APH PF01636.23 GAM39295.1 - 0.03 14.2 0.2 0.12 12.3 0.2 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_S13 PF02113.15 GAM39295.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family ABC_tran PF00005.27 GAM39296.1 - 8.7e-43 146.1 0.0 4.2e-20 72.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAM39296.1 - 3.2e-26 92.6 33.0 2.1e-24 86.6 14.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GAM39296.1 - 3e-10 39.9 0.6 0.073 12.5 0.2 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAM39296.1 - 1.9e-08 34.5 7.3 0.072 12.9 0.1 4.7 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAM39296.1 - 5.7e-08 33.1 0.0 0.0031 17.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GAM39296.1 - 1.9e-07 30.7 0.5 0.029 14.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM39296.1 - 2.8e-07 31.1 0.1 0.013 15.9 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAM39296.1 - 1.1e-06 28.7 0.2 0.018 15.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 GAM39296.1 - 1.5e-05 24.2 0.2 0.0065 15.6 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 GAM39296.1 - 1.5e-05 25.0 0.1 0.2 11.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 GAM39296.1 - 4.9e-05 23.2 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 GAM39296.1 - 7.9e-05 23.2 0.0 0.11 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GAM39296.1 - 9.3e-05 22.0 0.0 0.53 9.8 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 GAM39296.1 - 0.00015 22.4 0.8 0.79 10.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 GAM39296.1 - 0.00019 21.6 0.8 0.0089 16.1 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA PF00004.29 GAM39296.1 - 0.00033 21.1 0.0 0.64 10.4 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAM39296.1 - 0.00033 20.8 0.0 0.1 12.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 GAM39296.1 - 0.00035 20.2 0.2 0.029 14.0 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 GAM39296.1 - 0.0006 19.9 0.4 0.37 10.8 0.1 2.4 2 0 0 2 2 2 1 Dynamin family SbcCD_C PF13558.6 GAM39296.1 - 0.0017 18.6 2.3 0.4 10.9 0.3 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 GAM39296.1 - 0.0028 17.0 0.0 0.47 9.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.18 GAM39296.1 - 0.0034 16.8 0.2 1.3 8.4 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 GAM39296.1 - 0.0043 16.9 0.1 0.11 12.2 0.1 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.21 GAM39296.1 - 0.0052 16.2 0.0 2.2 7.6 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.7 GAM39296.1 - 0.012 14.6 0.0 3.1 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.22 GAM39296.1 - 0.017 15.5 0.0 5.6 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Adeno_IVa2 PF02456.15 GAM39296.1 - 0.017 13.9 0.1 4.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF3987 PF13148.6 GAM39296.1 - 0.019 14.0 0.0 0.26 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) IstB_IS21 PF01695.17 GAM39296.1 - 0.021 14.6 0.5 14 5.3 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein GTP_EFTU PF00009.27 GAM39296.1 - 0.026 14.1 0.0 9.3 5.7 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF815 PF05673.13 GAM39296.1 - 0.027 13.7 0.0 4.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 GAM39296.1 - 0.028 14.4 0.2 9.2 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 GAM39296.1 - 0.037 13.8 0.4 0.43 10.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 GAM39296.1 - 0.038 13.7 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAM39296.1 - 0.072 12.7 1.4 3.5 7.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 GAM39296.1 - 0.078 12.9 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 NACHT domain CLP1_P PF16575.5 GAM39296.1 - 0.089 12.6 0.4 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 GAM39296.1 - 0.099 12.6 0.0 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 GAM39296.1 - 0.16 10.9 0.0 9.1 5.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 GAM39296.1 - 0.21 11.8 0.1 28 5.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 GAM39296.1 - 0.21 11.5 0.5 15 5.4 0.2 2.5 2 0 0 2 2 2 0 NTPase dNK PF01712.19 GAM39296.1 - 0.24 11.2 0.2 7.9 6.3 0.1 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase Lgl_C PF08596.10 GAM39297.1 - 6.7e-133 443.2 0.0 2e-132 441.7 0.0 1.7 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 GAM39297.1 - 0.00047 20.4 0.0 2.9 8.2 0.0 5.3 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAM39297.1 - 0.032 15.1 5.9 6.3 7.8 0.0 4.9 6 0 0 6 6 6 0 WD domain, G-beta repeat Nup160 PF11715.8 GAM39297.1 - 0.11 11.1 0.5 5.7 5.5 0.0 3.3 4 1 1 5 5 5 0 Nucleoporin Nup120/160 ASF1_hist_chap PF04729.13 GAM39298.1 - 1.8e-74 248.8 0.0 2.6e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 GAM39298.1 - 0.01 14.1 21.1 0.013 13.7 21.1 1.0 1 0 0 1 1 1 0 Nop14-like family Suf PF05843.14 GAM39299.1 - 8e-89 298.5 10.1 2.2e-87 293.8 0.0 4.2 5 0 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 GAM39299.1 - 1.5e-05 25.4 3.4 1.5 9.9 0.0 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat HAT PF02184.16 GAM39299.1 - 0.003 17.5 0.3 0.03 14.3 0.2 2.5 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat TPR_16 PF13432.6 GAM39299.1 - 0.0065 17.1 0.3 0.17 12.6 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM39299.1 - 0.015 15.8 0.0 37 4.9 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat SPT6_acidic PF14632.6 GAM39299.1 - 7.8 7.2 19.5 0.4 11.3 5.9 2.6 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Aft1_HRA PF11786.8 GAM39302.1 - 9.6e-25 86.7 8.6 9.6e-25 86.7 8.6 2.8 2 1 1 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.8 GAM39302.1 - 1.6e-23 83.7 2.2 1.6e-23 83.7 2.2 4.1 3 1 0 3 3 3 1 Aft1 HRR domain Aft1_OSA PF11785.8 GAM39302.1 - 2.1e-19 69.7 16.6 3.1e-19 69.1 13.4 2.7 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 GAM39302.1 - 8.3e-13 48.2 4.7 1.6e-12 47.3 4.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAM39302.1 - 1.4e-05 25.0 5.4 2.8e-05 24.1 5.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAM39302.1 - 0.0023 18.4 2.1 0.0058 17.1 2.1 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor GCP_C_terminal PF04130.13 GAM39303.1 - 2e-101 339.5 1.2 4.1e-101 338.5 1.2 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GAM39303.1 - 4.4e-86 289.3 0.0 4.4e-85 286.0 0.0 2.2 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF2373 PF10180.9 GAM39304.1 - 2.7e-23 81.6 0.2 5.9e-23 80.5 0.2 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Egh16-like PF11327.8 GAM39305.1 - 5.4e-70 235.5 10.3 7e-70 235.2 10.3 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor Amidase PF01425.21 GAM39306.1 - 2.2e-40 139.0 0.3 3.1e-40 138.5 0.2 1.2 1 1 0 1 1 1 1 Amidase Proteasome PF00227.26 GAM39307.1 - 1.9e-28 99.3 0.1 3e-28 98.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAM39307.1 - 9.3e-13 47.6 0.2 1.5e-12 47.0 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Peptidase_S24 PF00717.23 GAM39308.1 - 7.7e-08 32.2 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like UQ_con PF00179.26 GAM39309.1 - 1.3e-42 144.8 0.0 1.4e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM39309.1 - 7.9e-08 32.1 0.0 9.9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAM39309.1 - 0.0041 17.4 0.1 0.0058 16.9 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 GAM39309.1 - 0.044 13.6 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 UEV domain RabGAP-TBC PF00566.18 GAM39310.1 - 5.7e-33 114.4 0.0 1.1e-31 110.2 0.0 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain CFEM PF05730.11 GAM39311.1 - 0.00077 19.5 9.0 0.00077 19.5 9.0 2.2 2 0 0 2 2 2 1 CFEM domain DUF3040 PF11239.8 GAM39311.1 - 0.12 12.7 1.5 1.5 9.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) SOG2 PF10428.9 GAM39311.1 - 1.2 8.3 16.0 1.4 8.1 16.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ABC_tran PF00005.27 GAM39312.1 - 1.4e-45 155.2 0.0 8.9e-24 84.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAM39312.1 - 4.8e-25 88.8 20.1 1.9e-24 86.8 11.0 2.8 2 1 1 3 3 3 1 ABC transporter transmembrane region T2SSE PF00437.20 GAM39312.1 - 1.8e-10 40.3 0.6 3e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.19 GAM39312.1 - 3.1e-10 39.8 1.1 0.0018 17.8 0.0 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAM39312.1 - 7.6e-10 39.1 3.9 0.038 13.8 0.0 3.8 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAM39312.1 - 8.1e-09 35.9 0.1 0.0021 18.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GAM39312.1 - 4.2e-08 32.8 2.9 0.001 18.8 0.1 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM39312.1 - 4.5e-07 29.9 1.1 0.049 13.5 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 GAM39312.1 - 8.1e-07 29.6 0.4 0.016 15.6 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 GAM39312.1 - 1.2e-06 29.2 1.5 0.0026 18.3 0.4 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 GAM39312.1 - 2.2e-06 27.2 0.1 0.0083 15.5 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 GAM39312.1 - 2.2e-06 27.7 0.0 0.014 15.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 GAM39312.1 - 8e-06 25.6 0.3 0.035 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 GAM39312.1 - 3.3e-05 23.9 0.9 0.37 10.7 0.0 3.1 3 0 0 3 3 3 2 NTPase Viral_helicase1 PF01443.18 GAM39312.1 - 4.2e-05 23.4 0.3 0.11 12.2 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.15 GAM39312.1 - 0.00011 21.2 0.5 0.005 15.7 0.1 2.5 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_33 PF13671.6 GAM39312.1 - 0.00014 22.0 0.0 0.51 10.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain Dynamin_N PF00350.23 GAM39312.1 - 0.00035 20.7 0.1 0.23 11.5 0.0 2.5 2 0 0 2 2 2 1 Dynamin family cobW PF02492.19 GAM39312.1 - 0.00039 20.0 2.7 0.2 11.2 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 GAM39312.1 - 0.00045 20.4 1.4 0.71 9.9 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain NACHT PF05729.12 GAM39312.1 - 0.0011 18.9 1.8 0.83 9.5 0.1 3.0 3 0 0 3 3 2 2 NACHT domain ATPase_2 PF01637.18 GAM39312.1 - 0.0013 18.7 0.2 3 7.7 0.0 3.4 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 GAM39312.1 - 0.0014 19.2 0.1 1.9 9.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 GAM39312.1 - 0.0016 18.0 0.2 1.5 8.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 GAM39312.1 - 0.0018 17.6 0.7 2.2 7.5 0.1 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_30 PF13604.6 GAM39312.1 - 0.0019 18.0 0.1 0.21 11.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 GAM39312.1 - 0.0023 16.8 3.5 0.89 8.3 0.0 3.8 4 1 0 4 4 4 1 Predicted ATPase of the ABC class RNA_helicase PF00910.22 GAM39312.1 - 0.0055 17.1 0.0 3 8.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.6 GAM39312.1 - 0.0058 16.4 1.4 0.87 9.2 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 GAM39312.1 - 0.0066 15.8 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 GAM39312.1 - 0.0095 16.2 2.1 1.4 9.2 0.6 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 GAM39312.1 - 0.012 15.3 0.6 18 5.0 0.0 3.6 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_24 PF13479.6 GAM39312.1 - 0.019 14.7 0.0 0.91 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GAM39312.1 - 0.02 15.3 0.2 2 8.8 0.1 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 GAM39312.1 - 0.026 13.7 0.3 2.8 7.1 0.1 2.6 2 1 0 2 2 2 0 NB-ARC domain DAP3 PF10236.9 GAM39312.1 - 0.027 13.7 3.4 2.6 7.1 0.1 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.6 GAM39312.1 - 0.03 14.4 0.1 5.5 7.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 GAM39312.1 - 0.04 13.7 0.1 5 6.9 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_27 PF13514.6 GAM39312.1 - 0.044 13.4 0.4 1 8.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain CbiA PF01656.23 GAM39312.1 - 0.06 13.4 1.0 3.7 7.6 0.1 2.9 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 GAM39312.1 - 0.084 12.1 0.0 13 4.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 GAM39312.1 - 0.087 13.2 0.2 5.8 7.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 GAM39312.1 - 0.091 12.8 0.3 5.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA12 PF10443.9 GAM39312.1 - 0.098 11.4 0.3 0.32 9.7 0.0 1.8 2 0 0 2 2 2 0 RNA12 protein Pox_A32 PF04665.12 GAM39312.1 - 0.11 11.9 0.7 1.7 8.1 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 GAM39312.1 - 0.12 12.1 0.3 19 4.9 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 GAM39312.1 - 0.17 11.1 0.1 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Septin Rad17 PF03215.15 GAM39312.1 - 0.18 11.7 0.4 15 5.5 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_5 PF07728.14 GAM39312.1 - 0.27 11.3 2.4 20 5.1 0.2 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) dNK PF01712.19 GAM39312.1 - 0.88 9.4 2.9 27 4.5 0.1 3.0 3 0 0 3 3 3 0 Deoxynucleoside kinase ATPase PF06745.13 GAM39312.1 - 1.2 8.4 3.3 85 2.4 0.0 3.7 4 0 0 4 4 4 0 KaiC BCS1_N PF08740.11 GAM39314.1 - 1.1e-47 162.4 0.5 1.5e-47 162.0 0.5 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 GAM39314.1 - 1.9e-17 63.9 0.0 3.4e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM39314.1 - 1.5e-05 25.4 0.0 3.9e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 GAM39314.1 - 0.0014 17.8 0.0 0.0027 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 GAM39314.1 - 0.005 17.0 0.0 0.0094 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAM39314.1 - 0.0054 17.2 0.0 0.012 16.1 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 GAM39314.1 - 0.0084 15.8 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 GAM39314.1 - 0.018 15.1 0.0 0.082 12.9 0.0 2.1 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 GAM39314.1 - 0.024 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 GAM39314.1 - 0.027 15.0 0.0 0.059 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAM39314.1 - 0.039 14.2 0.0 0.096 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM39314.1 - 0.048 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 GAM39314.1 - 0.054 13.9 0.0 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 GAM39314.1 - 0.068 13.1 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 GAM39314.1 - 0.08 12.5 0.0 0.57 9.7 0.0 2.2 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 GAM39314.1 - 0.15 12.0 0.0 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Viral_helicase1 PF01443.18 GAM39314.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 GAM39314.1 - 0.18 11.6 0.0 0.41 10.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain Cpn60_TCP1 PF00118.24 GAM39316.1 - 1.1e-175 585.0 0.8 1.2e-175 584.8 0.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.12 GAM39317.1 - 4.9e-39 133.2 10.3 7.8e-39 132.6 10.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 GAM39317.1 - 0.026 13.7 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 Lyase, catalytic DUF4407 PF14362.6 GAM39317.1 - 0.29 10.5 2.1 0.33 10.3 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PPL5 PF18168.1 GAM39317.1 - 0.41 9.9 3.8 0.55 9.5 3.8 1.1 1 0 0 1 1 1 0 Prim-pol family 5 RR_TM4-6 PF06459.12 GAM39317.1 - 1 9.1 7.5 1.6 8.5 7.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 GAM39317.1 - 4.6 5.9 7.8 5.6 5.6 7.8 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 GAM39317.1 - 5.7 7.0 8.2 8.4 6.4 8.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC45 PF02724.14 GAM39317.1 - 6.1 5.0 11.9 7.5 4.7 11.9 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 GAM39317.1 - 8 5.1 7.5 9.7 4.8 7.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein zf-PARP PF00645.18 GAM39318.1 - 1e-22 80.8 0.2 3.5e-22 79.0 0.2 2.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region adh_short PF00106.25 GAM39319.1 - 2.3e-37 128.4 0.9 4.9e-37 127.3 0.9 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM39319.1 - 8.5e-31 107.3 0.8 1.8e-30 106.3 0.8 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM39319.1 - 6.5e-12 45.7 0.3 9.5e-12 45.2 0.3 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAM39319.1 - 0.00036 20.5 0.6 0.00051 20.0 0.6 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM39319.1 - 0.00085 18.8 0.9 0.0028 17.2 0.9 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAM39319.1 - 0.0016 18.7 0.1 0.0037 17.5 0.1 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain IlvN PF07991.12 GAM39319.1 - 0.039 13.5 0.4 0.059 13.0 0.4 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 GAM39319.1 - 0.12 13.0 0.4 0.55 10.8 0.4 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 GAM39319.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Kinesin PF00225.23 GAM39320.1 - 4.1e-60 203.5 0.0 5.8e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAM39320.1 - 2.8e-12 46.8 0.0 8.9e-11 41.9 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding CCDC106 PF15794.5 GAM39320.1 - 0.0057 16.4 0.2 0.018 14.8 0.2 1.8 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 AAA_13 PF13166.6 GAM39320.1 - 0.012 14.3 1.0 0.018 13.8 1.0 1.1 1 0 0 1 1 1 0 AAA domain bZIP_2 PF07716.15 GAM39320.1 - 0.027 14.6 0.6 0.089 12.9 0.6 1.9 1 0 0 1 1 1 0 Basic region leucine zipper Stathmin PF00836.19 GAM39320.1 - 0.16 11.9 9.2 0.4 10.7 9.2 1.6 1 0 0 1 1 1 0 Stathmin family T3SSipB PF16535.5 GAM39320.1 - 0.25 11.8 1.3 0.55 10.7 1.3 1.5 1 0 0 1 1 1 0 Type III cell invasion protein SipB Med21 PF11221.8 GAM39320.1 - 0.66 10.2 6.3 0.28 11.4 1.2 2.8 3 0 0 3 3 3 0 Subunit 21 of Mediator complex APG6_N PF17675.1 GAM39320.1 - 1.4 9.4 16.8 7.8 7.0 5.4 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region TPR_11 PF13414.6 GAM39321.1 - 0.029 14.0 0.8 0.11 12.2 0.8 2.0 1 0 0 1 1 1 0 TPR repeat MttA_Hcf106 PF02416.16 GAM39321.1 - 0.08 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 mttA/Hcf106 family TPR_2 PF07719.17 GAM39321.1 - 8.3 6.8 6.8 16 5.9 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 GAM39322.1 - 1.8e-153 511.2 0.0 2.3e-153 510.9 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 GAM39322.1 - 4.2e-07 30.2 5.3 0.25 12.3 0.1 5.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM39322.1 - 4.1e-06 26.5 0.4 0.0018 18.2 0.1 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM39322.1 - 1.7e-05 24.5 0.1 0.02 14.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM39322.1 - 3.4e-05 24.3 1.1 0.28 11.7 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM39322.1 - 0.00029 20.8 0.0 0.023 14.9 0.0 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM39322.1 - 0.0022 18.3 2.8 0.69 10.3 0.3 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM39322.1 - 0.0037 17.2 0.6 0.41 10.8 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAM39322.1 - 0.013 14.8 0.4 0.31 10.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAM39322.1 - 0.081 13.1 0.1 4.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Zn_clus PF00172.18 GAM39324.1 - 5.4e-06 26.4 10.7 9.9e-06 25.6 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM39324.1 - 2.2e-05 23.6 0.8 6e-05 22.2 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1667 PF07892.11 GAM39324.1 - 0.026 14.6 0.3 0.059 13.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) Epimerase PF01370.21 GAM39325.1 - 4.6e-23 81.9 0.0 6e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM39325.1 - 1.1e-19 71.1 0.0 3e-19 69.6 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAM39325.1 - 1.8e-10 40.3 0.0 2.1e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAM39325.1 - 1.1e-07 31.3 0.0 1.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAM39325.1 - 8.5e-06 25.1 0.0 0.12 11.5 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 GAM39325.1 - 0.002 17.3 0.0 0.019 14.1 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAM39325.1 - 0.0022 17.9 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 GAM39325.1 - 0.005 16.7 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 GAM39325.1 - 0.0078 15.7 0.0 0.019 14.4 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Ldh_1_N PF00056.23 GAM39325.1 - 0.032 14.3 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain SHNi-TPR PF10516.9 GAM39325.1 - 0.065 12.7 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 SHNi-TPR DUF3292 PF11696.8 GAM39326.1 - 5.4e-282 937.0 0.0 6.2e-282 936.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) PRT_C PF08372.10 GAM39326.1 - 0.0062 16.3 0.0 0.42 10.4 0.1 2.2 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal DUF2182 PF09948.9 GAM39326.1 - 0.2 11.5 1.3 0.37 10.6 1.3 1.3 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) ERCC4 PF02732.15 GAM39327.1 - 6.1e-27 94.7 0.0 9.8e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain Ish1 PF10281.9 GAM39327.1 - 0.029 14.7 0.4 0.11 12.8 0.0 2.3 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein E1-E2_ATPase PF00122.20 GAM39328.1 - 4.3e-54 182.8 0.2 4.3e-54 182.8 0.2 2.9 3 1 1 4 4 4 1 E1-E2 ATPase HMA PF00403.26 GAM39328.1 - 4.4e-50 168.0 11.1 1.1e-12 48.2 0.0 5.6 5 0 0 5 5 5 5 Heavy-metal-associated domain Hydrolase PF00702.26 GAM39328.1 - 2.2e-34 119.6 0.4 4e-34 118.8 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAM39328.1 - 1e-06 28.7 0.7 0.0014 18.4 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase RRM_3 PF08777.11 GAM39328.1 - 0.00055 19.9 0.4 9 6.4 0.0 4.2 4 0 0 4 4 4 1 RNA binding motif DUF1269 PF06897.12 GAM39328.1 - 0.0013 19.0 2.0 0.1 12.9 0.0 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF1269) HAD PF12710.7 GAM39328.1 - 0.056 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 GAM39328.1 - 0.095 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Fer2_BFD PF04324.15 GAM39328.1 - 5.9 7.3 13.3 83 3.6 0.0 5.9 5 1 0 5 5 5 0 BFD-like [2Fe-2S] binding domain TFIIB PF00382.19 GAM39329.1 - 5e-35 119.4 1.4 1.8e-18 66.3 0.2 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 GAM39329.1 - 2e-26 92.3 0.0 2e-26 92.3 0.0 3.8 3 1 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 GAM39329.1 - 0.0027 17.4 0.3 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.12 GAM39329.1 - 0.024 14.1 3.6 0.056 13.0 3.6 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding TPT PF03151.16 GAM39331.1 - 6.9e-24 84.7 24.6 8.3e-24 84.4 24.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GAM39331.1 - 1 8.5 26.3 1.6 7.8 26.3 1.2 1 0 0 1 1 1 0 UAA transporter family NAD_binding_8 PF13450.6 GAM39332.1 - 3.6e-08 33.5 0.0 7.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAM39332.1 - 2.2e-07 30.5 0.0 3.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 GAM39332.1 - 0.0043 16.3 0.1 0.017 14.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM39332.1 - 0.0063 15.8 0.2 0.0097 15.2 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAM39332.1 - 0.014 14.7 0.1 0.028 13.7 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 GAM39332.1 - 0.018 14.6 0.1 0.03 13.9 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAM39332.1 - 0.028 13.8 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 GAM39332.1 - 0.031 13.5 0.1 0.058 12.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 GAM39332.1 - 0.088 11.8 0.2 0.17 10.9 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 GAM39332.1 - 0.18 10.5 0.1 0.25 10.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pkinase PF00069.25 GAM39334.1 - 1.8e-66 224.2 0.0 2.5e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM39334.1 - 2.2e-31 109.1 0.0 6.2e-30 104.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAM39334.1 - 0.00037 19.9 0.0 0.00063 19.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAM39334.1 - 0.0019 17.5 0.0 0.0049 16.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 GAM39334.1 - 0.0036 17.0 0.0 0.018 14.7 0.0 1.9 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 GAM39334.1 - 0.0091 15.9 0.0 0.027 14.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM39334.1 - 0.031 13.2 0.2 0.055 12.4 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Peptidase_S9 PF00326.21 GAM39335.1 - 3.4e-15 56.1 0.0 4.9e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 GAM39335.1 - 2.1e-07 31.0 0.3 4.6e-06 26.6 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM39335.1 - 0.00012 21.5 0.2 0.024 13.9 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 GAM39335.1 - 0.0016 18.0 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.9 GAM39335.1 - 0.018 14.5 0.3 0.025 14.1 0.3 1.1 1 0 0 1 1 1 0 Esterase PHB depolymerase Fungal_trans_2 PF11951.8 GAM39336.1 - 5.1e-30 104.5 0.6 6.2e-30 104.3 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain BTB PF00651.31 GAM39337.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain MFS_1 PF07690.16 GAM39338.1 - 2.3e-31 109.0 23.2 2.4e-31 109.0 21.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 GAM39339.1 - 2.1e-93 313.1 6.6 2.4e-93 313.0 6.6 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Bep_C_terminal PF17841.1 GAM39339.1 - 0.0062 16.7 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 BID domain of Bartonella effector protein (Bep) Glyco_hydro_127 PF07944.12 GAM39339.1 - 0.0065 15.0 0.6 0.0065 15.0 0.6 1.4 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 Pro_CA PF00484.19 GAM39340.1 - 3.9e-05 24.0 0.1 0.0041 17.4 0.0 2.1 1 1 1 2 2 2 2 Carbonic anhydrase Cytochrom_B561 PF03188.16 GAM39341.1 - 4.4e-13 49.6 3.6 4.4e-13 49.6 3.6 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 GAM39341.1 - 0.083 13.0 14.8 1.4 9.1 8.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) DUF4271 PF14093.6 GAM39341.1 - 0.11 12.4 11.2 0.062 13.2 9.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) tRNA-synt_2b PF00587.25 GAM39342.1 - 5.4e-18 65.6 0.0 1.1e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 GAM39342.1 - 3.8e-10 39.9 8.1 6.8e-10 39.1 8.1 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain ERM PF00769.19 GAM39342.1 - 0.018 14.9 8.4 0.032 14.1 8.4 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.9 GAM39342.1 - 0.068 13.4 7.4 0.14 12.4 7.4 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 GAM39342.1 - 0.1 12.0 3.3 0.2 11.0 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BBS1 PF14779.6 GAM39342.1 - 0.14 11.6 2.4 0.15 11.5 1.3 1.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 TMF_TATA_bd PF12325.8 GAM39342.1 - 0.25 11.5 7.3 0.55 10.5 7.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CENP-Q PF13094.6 GAM39342.1 - 0.34 11.1 10.1 0.55 10.4 10.1 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMPIT PF07851.13 GAM39342.1 - 0.71 9.1 5.1 1.6 7.9 5.2 1.4 2 0 0 2 2 2 0 TMPIT-like protein Ax_dynein_light PF10211.9 GAM39342.1 - 0.83 9.6 7.9 1.5 8.7 7.9 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain Med4 PF10018.9 GAM39342.1 - 0.9 9.2 9.2 0.2 11.3 2.3 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Mis14 PF08641.12 GAM39342.1 - 0.9 9.9 6.1 0.4 11.0 3.6 1.7 2 0 0 2 2 1 0 Kinetochore protein Mis14 like Occludin_ELL PF07303.13 GAM39342.1 - 1.2 10.0 5.7 2.3 9.0 5.7 1.5 1 0 0 1 1 1 0 Occludin homology domain UPF0242 PF06785.11 GAM39342.1 - 1.4 9.0 6.8 2.4 8.2 6.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 GAM39342.1 - 2 7.5 6.9 3.4 6.7 6.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 GAM39342.1 - 2.1 8.7 7.9 4.1 7.8 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FapA PF03961.13 GAM39342.1 - 7.9 5.0 11.6 1.8 7.1 8.5 1.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A Allantoicase PF03561.15 GAM39343.1 - 1.7e-89 297.2 0.0 5.2e-44 149.7 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat HATPase_c PF02518.26 GAM39344.1 - 1.4e-30 106.1 0.0 5.4e-30 104.2 0.0 2.1 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM39344.1 - 3.8e-21 75.3 0.0 1.1e-20 73.9 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAM39344.1 - 3.1e-19 68.8 0.0 1.3e-18 66.7 0.0 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 GAM39344.1 - 3.2e-13 50.2 0.0 9.5e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.6 GAM39344.1 - 7.3e-13 49.3 1.9 1.2e-11 45.2 0.0 3.3 4 0 0 4 4 4 1 AAA ATPase domain GAF PF01590.26 GAM39344.1 - 6.8e-07 30.0 0.0 2.7e-06 28.1 0.0 2.1 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 GAM39344.1 - 2.6e-05 24.6 0.0 6.2e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 GAM39344.1 - 0.00017 21.1 0.0 0.001 18.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain NB-ARC PF00931.22 GAM39344.1 - 0.0008 18.7 1.4 0.017 14.3 0.5 2.9 2 1 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 GAM39344.1 - 0.0031 17.8 0.1 0.59 10.4 0.0 3.8 3 1 0 3 3 2 1 AAA domain HATPase_c_3 PF13589.6 GAM39344.1 - 0.0051 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MeaB PF03308.16 GAM39344.1 - 0.0056 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 GAM39344.1 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 NTPase DUF2514 PF10721.9 GAM39344.1 - 0.0095 16.0 1.4 0.023 14.8 1.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) NACHT PF05729.12 GAM39344.1 - 0.039 13.9 0.1 1 9.3 0.0 2.9 3 0 0 3 3 2 0 NACHT domain TPR_16 PF13432.6 GAM39344.1 - 3.9 8.2 12.2 6.9 7.4 1.1 3.7 3 1 1 4 4 3 0 Tetratricopeptide repeat HATPase_c PF02518.26 GAM39345.1 - 3.5e-22 79.0 0.4 3.4e-21 75.9 0.0 2.7 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM39345.1 - 5.8e-22 78.0 0.4 2e-21 76.3 0.2 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAM39345.1 - 9.1e-17 60.9 0.1 2.5e-16 59.5 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 GAM39345.1 - 9.4e-15 54.7 0.3 1.5e-05 25.2 0.2 3.8 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 GAM39345.1 - 1e-06 28.9 0.2 5.8e-06 26.5 0.0 2.5 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 GAM39345.1 - 3.8e-06 26.9 0.0 0.0092 16.0 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 GAM39345.1 - 1.4e-05 25.2 0.0 0.26 11.6 0.0 4.2 3 1 0 3 3 3 2 PAS domain MotA_ExbB PF01618.16 GAM39345.1 - 0.13 12.1 0.5 0.75 9.6 0.0 2.3 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Aldo_ket_red PF00248.21 GAM39346.1 - 7.8e-49 166.4 0.0 8.8e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RTA1 PF04479.13 GAM39347.1 - 3e-71 239.3 7.5 4.9e-71 238.6 7.5 1.3 1 0 0 1 1 1 1 RTA1 like protein MFS_1 PF07690.16 GAM39348.1 - 2.3e-44 151.8 22.1 2.3e-44 151.8 22.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM39348.1 - 3.4e-13 49.3 0.1 3.4e-13 49.3 0.1 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAM39348.1 - 1.2e-06 27.3 1.1 1.6e-06 26.8 1.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 GAM39348.1 - 0.0015 17.4 0.4 0.0062 15.4 0.0 1.9 2 0 0 2 2 2 1 MFS_1 like family MFS_3 PF05977.13 GAM39348.1 - 0.0027 16.2 2.8 0.0027 16.2 2.8 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.20 GAM39348.1 - 0.0045 15.3 1.5 0.017 13.5 0.4 2.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Fringe PF02434.16 GAM39349.1 - 1.4e-12 47.6 0.0 2.3e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 GAM39349.1 - 0.011 15.6 0.0 0.06 13.2 0.0 2.0 1 1 0 1 1 1 0 Galactosyltransferase PAN_4 PF14295.6 GAM39349.1 - 0.081 12.8 2.5 0.22 11.5 2.5 1.7 1 0 0 1 1 1 0 PAN domain Polysacc_deac_1 PF01522.21 GAM39350.1 - 2.5e-18 66.1 0.0 5.2e-18 65.1 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 GAM39350.1 - 0.029 13.6 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase ERCC3_RAD25_C PF16203.5 GAM39351.1 - 0.12 11.6 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AntA PF08346.12 GAM39352.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 AntA/AntB antirepressor Sugar_tr PF00083.24 GAM39353.1 - 9.7e-78 262.0 23.4 1.1e-77 261.8 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM39353.1 - 3.1e-20 72.4 34.3 4e-18 65.5 28.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 GAM39354.1 - 3.8e-13 49.1 50.7 2.9e-12 46.2 17.9 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily ADH_N PF08240.12 GAM39355.1 - 1.1e-09 38.1 0.0 2.7e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM39355.1 - 1.2e-08 35.0 0.3 2.3e-08 34.1 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 GAM39355.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase RAI16-like PF10257.9 GAM39356.1 - 6.5e-87 291.7 0.5 9.5e-87 291.2 0.5 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Amino_oxidase PF01593.24 GAM39356.1 - 1.4e-62 212.4 0.2 1.9e-60 205.5 0.1 2.7 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM39356.1 - 7.2e-09 35.8 0.1 1.5e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM39356.1 - 0.03 13.6 0.1 0.097 11.9 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM39356.1 - 0.055 12.7 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 GAM39356.1 - 0.065 12.5 0.1 0.74 9.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM39356.1 - 0.085 11.5 0.0 0.17 10.5 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 GAM39356.1 - 0.13 11.5 0.1 0.3 10.3 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 GAM39356.1 - 0.31 11.6 0.9 7.7 7.2 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 GAM39358.1 - 6.5e-69 232.9 0.0 7.5e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CBFD_NFYB_HMF PF00808.23 GAM39359.1 - 2.2e-15 56.7 3.2 4.9e-15 55.6 3.2 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAM39359.1 - 5.1e-05 23.7 4.7 6.5e-05 23.3 3.6 1.9 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIIA PF03153.13 GAM39359.1 - 0.00014 22.0 15.1 0.00016 21.8 15.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PCP_red PF08369.10 GAM39359.1 - 0.18 12.0 2.8 0.25 11.6 0.5 2.2 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit CENP-X PF09415.10 GAM39359.1 - 1.4 9.3 3.9 0.63 10.4 1.2 1.9 2 0 0 2 2 2 0 CENP-S associating Centromere protein X zf-C3HC4_3 PF13920.6 GAM39360.1 - 0.00085 19.1 12.1 0.0016 18.3 12.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) adh_short_C2 PF13561.6 GAM39361.1 - 3.1e-31 108.7 0.2 3.9e-31 108.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM39361.1 - 9.3e-21 74.2 0.0 1.3e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM39361.1 - 2.1e-08 34.3 0.1 3.5e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 GAM39361.1 - 0.0074 16.7 0.1 0.091 13.2 0.1 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 GAM39361.1 - 0.011 16.0 0.1 0.046 14.0 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_12 PF08242.12 GAM39361.1 - 0.064 14.0 0.0 0.11 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF1098 PF06497.11 GAM39361.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) Sugar_tr PF00083.24 GAM39362.1 - 3e-76 257.1 15.7 3.5e-76 256.9 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM39362.1 - 5.7e-12 45.2 37.0 1.7e-09 37.1 19.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM39363.1 - 3.6e-21 75.4 0.0 5.5e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM39363.1 - 0.011 15.8 12.6 0.021 15.0 12.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-amylase PF00128.24 GAM39364.1 - 1.1e-103 347.3 0.1 1.7e-103 346.8 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 GAM39364.1 - 4.4e-05 23.5 0.1 0.00022 21.3 0.1 2.1 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 GAM39364.1 - 0.013 14.6 0.1 0.023 13.8 0.1 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Methyltransf_23 PF13489.6 GAM39365.1 - 2e-16 60.3 0.0 3.4e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GFA PF04828.14 GAM39365.1 - 3.4e-08 33.7 0.1 1.3e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_31 PF13847.6 GAM39365.1 - 3.1e-07 30.3 0.0 0.0011 18.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 GAM39365.1 - 1.9e-06 28.5 0.0 7.9e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM39365.1 - 5.3e-05 23.9 0.0 0.0061 17.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM39365.1 - 0.0028 18.3 0.0 0.019 15.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAM39365.1 - 0.042 13.4 0.0 0.099 12.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 GAM39365.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 GAM39365.1 - 0.19 11.0 0.0 1.1 8.5 0.0 2.1 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family MFS_1 PF07690.16 GAM39366.1 - 8.5e-21 74.3 25.1 8.5e-21 74.3 25.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5465 PF17553.2 GAM39366.1 - 0.33 11.5 1.6 8.8 7.2 0.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5465) Pkinase PF00069.25 GAM39367.1 - 0.0018 17.7 0.0 0.0058 16.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Acetyltransf_7 PF13508.7 GAM39368.1 - 0.0017 18.7 0.0 0.0047 17.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM39368.1 - 0.02 14.9 0.1 0.63 10.0 0.0 2.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM39368.1 - 0.085 13.1 0.0 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family FAD_binding_4 PF01565.23 GAM39369.1 - 2e-22 79.4 0.0 4.3e-22 78.3 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAM39369.1 - 0.00036 20.6 1.9 0.00046 20.2 0.1 2.1 2 0 0 2 2 2 1 Berberine and berberine like LIP PF03583.14 GAM39370.1 - 5.2e-75 252.4 0.1 6.8e-75 252.0 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Kinesin PF00225.23 GAM39371.1 - 6.6e-103 344.1 0.0 6.6e-103 344.1 0.0 2.1 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAM39371.1 - 3e-60 202.5 0.0 9.7e-60 200.8 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding Bac_DnaA PF00308.18 GAM39371.1 - 0.0012 18.8 0.5 0.0055 16.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial dnaA protein Lebercilin PF15619.6 GAM39371.1 - 0.0016 18.2 17.9 0.0016 18.2 17.9 3.9 2 1 2 4 4 4 1 Ciliary protein causing Leber congenital amaurosis disease AAA_24 PF13479.6 GAM39371.1 - 0.014 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAM39371.1 - 0.023 15.1 0.0 0.023 15.1 0.0 3.2 2 1 1 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 GAM39371.1 - 0.072 13.5 0.2 0.68 10.3 0.1 2.5 2 0 0 2 2 2 0 RNA helicase DUF3584 PF12128.8 GAM39371.1 - 0.094 10.2 34.3 0.24 8.9 34.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MAAL_C PF07476.11 GAM39371.1 - 0.26 10.4 2.6 0.15 11.2 0.4 1.6 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus AAA_22 PF13401.6 GAM39371.1 - 0.44 10.8 0.0 0.44 10.8 0.0 3.1 2 1 1 3 3 3 0 AAA domain DUF4854 PF16146.5 GAM39371.1 - 4 7.8 8.3 20 5.6 0.5 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4854) DUF1899 PF08953.11 GAM39372.1 - 2.7e-35 120.1 0.0 5e-35 119.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 GAM39372.1 - 1.4e-19 69.7 0.3 2.9e-19 68.7 0.3 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 GAM39372.1 - 5.8e-17 61.8 6.0 0.00054 20.7 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM39372.1 - 5.3e-05 23.4 0.0 0.76 10.1 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain HMMR_N PF15905.5 GAM39372.1 - 0.012 15.1 0.9 0.019 14.4 0.9 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Nup160 PF11715.8 GAM39372.1 - 0.028 13.1 4.4 0.84 8.2 0.2 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DivIC PF04977.15 GAM39372.1 - 0.21 11.4 4.0 0.11 12.3 0.7 2.0 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 GAM39372.1 - 0.43 11.2 3.3 0.27 11.9 1.1 1.8 2 0 0 2 2 2 0 SlyX Lipase_3 PF01764.25 GAM39373.1 - 2.5e-21 76.0 0.0 4.7e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 GAM39373.1 - 0.0013 19.4 0.5 0.006 17.2 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAM39373.1 - 0.018 14.8 0.0 0.052 13.3 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Chlorophyllase2 PF12740.7 GAM39373.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Acyltransferase PF01553.21 GAM39374.1 - 0.051 13.2 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase DUF3328 PF11807.8 GAM39377.1 - 3.9e-36 124.9 0.0 5.9e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_16 PF00722.21 GAM39378.1 - 9.3e-08 31.7 0.0 1.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Con-6 PF10346.9 GAM39380.1 - 2e-29 101.3 1.8 6.2e-16 58.1 0.1 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.7 GAM39380.1 - 0.1 12.4 0.4 9.8 5.9 0.0 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein Epimerase PF01370.21 GAM39381.1 - 3.9e-10 39.6 0.1 0.00038 20.0 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM39381.1 - 1.5e-07 31.5 0.4 2.6e-07 30.7 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM39381.1 - 1e-06 28.5 0.2 1.5e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 GAM39381.1 - 7.7e-06 26.4 0.1 1.6e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAM39381.1 - 4.3e-05 22.7 0.0 0.14 11.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAM39381.1 - 0.013 14.7 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.20 GAM39381.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4859 PF16151.5 GAM39381.1 - 0.08 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) UCH PF00443.29 GAM39383.1 - 1.5e-66 224.6 0.0 3.2e-66 223.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PX PF00787.24 GAM39383.1 - 4.2e-18 65.4 0.0 1.7e-17 63.4 0.0 2.1 1 0 0 1 1 1 1 PX domain DUSP PF06337.12 GAM39383.1 - 1.1e-14 54.7 0.0 4.6e-14 52.8 0.0 2.2 2 0 0 2 2 2 1 DUSP domain Vps5 PF09325.10 GAM39383.1 - 8.1e-05 22.3 14.0 0.0041 16.7 2.8 2.7 3 0 0 3 3 3 2 Vps5 C terminal like USP7_C2 PF14533.6 GAM39383.1 - 0.0013 18.5 0.0 0.028 14.1 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal Peptidase_C10 PF01640.17 GAM39383.1 - 0.076 13.3 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase C10 family PTase_Orf2 PF11468.8 GAM39384.1 - 2.6e-110 368.4 0.0 3.1e-110 368.1 0.0 1.1 1 0 0 1 1 1 1 Aromatic prenyltransferase Orf2 DUF2428 PF10350.9 GAM39385.1 - 3.3e-61 206.9 0.0 7.8e-61 205.7 0.0 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 GAM39385.1 - 0.0086 16.3 0.9 63 4.2 0.1 5.2 4 0 0 4 4 4 0 HEAT repeat AAA_14 PF13173.6 GAM39385.1 - 0.082 12.9 0.1 0.3 11.1 0.1 1.9 1 0 0 1 1 1 0 AAA domain HEAT_EZ PF13513.6 GAM39385.1 - 0.83 10.2 5.2 91 3.7 0.0 5.3 5 0 0 5 5 5 0 HEAT-like repeat Tim17 PF02466.19 GAM39386.1 - 1.3e-27 96.4 4.3 1.8e-27 95.9 4.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.25 GAM39387.1 - 3.4e-45 154.5 0.0 5.4e-44 150.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM39387.1 - 1.7e-26 93.1 0.0 2.5e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM39387.1 - 0.013 14.3 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase ILVD_EDD PF00920.21 GAM39388.1 - 1.7e-210 700.0 0.3 2.1e-210 699.8 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 GAM39388.1 - 0.045 14.0 0.1 0.45 10.7 0.0 2.3 1 1 0 2 2 2 0 5'-nucleotidase, C-terminal domain MHYT PF03707.16 GAM39389.1 - 2.7e-22 78.7 18.2 5.1e-08 32.9 0.1 4.5 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat GST_N_2 PF13409.6 GAM39390.1 - 2.3e-19 69.4 0.0 4.1e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM39390.1 - 6.2e-15 55.0 0.0 3.3e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM39390.1 - 7.5e-06 26.1 0.0 3e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM39390.1 - 0.00036 20.7 0.1 0.0013 18.8 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GAM39390.1 - 0.012 16.2 0.0 0.023 15.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NmrA PF05368.13 GAM39391.1 - 1.7e-14 53.9 0.0 2.8e-14 53.3 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM39391.1 - 1.3e-07 31.7 0.1 2.6e-07 30.7 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM39391.1 - 0.027 13.9 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pro_CA PF00484.19 GAM39392.1 - 2.2e-14 54.0 0.0 5.7e-14 52.7 0.0 1.7 1 1 0 1 1 1 1 Carbonic anhydrase Glycos_transf_2 PF00535.26 GAM39393.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 CCP_MauG PF03150.14 GAM39395.1 - 0.0081 16.8 0.0 0.0081 16.8 0.0 1.2 1 0 0 1 1 1 1 Di-haem cytochrome c peroxidase Fungal_trans PF04082.18 GAM39396.1 - 1.7e-11 43.7 0.4 2.7e-11 43.0 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_tran_CTD PF16326.5 GAM39396.1 - 0.0055 16.9 0.1 0.015 15.5 0.1 1.7 1 0 0 1 1 1 1 ABC transporter C-terminal domain ADP_ribosyl_GH PF03747.14 GAM39396.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase PKcGMP_CC PF16808.5 GAM39396.1 - 0.25 11.2 2.4 0.61 10.0 2.4 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ADH_N PF08240.12 GAM39397.1 - 6.4e-23 80.7 7.3 1.1e-22 80.0 7.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM39397.1 - 8.3e-14 51.7 0.0 1.3e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAM39397.1 - 0.00048 19.5 0.0 0.0008 18.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 GAM39397.1 - 0.0023 19.0 0.0 0.0059 17.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 GAM39397.1 - 0.033 13.9 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.6 GAM39397.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding AlaDh_PNT_C PF01262.21 GAM39397.1 - 0.16 11.2 0.0 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain WD40 PF00400.32 GAM39398.1 - 2.3e-43 145.3 25.0 9.6e-07 29.4 0.1 8.5 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 GAM39398.1 - 2.6e-14 52.8 0.7 5.7e-14 51.7 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM39398.1 - 1.5e-10 40.7 0.4 1.5e-10 40.7 0.4 2.8 2 1 1 3 3 3 1 F-box domain ANAPC4_WD40 PF12894.7 GAM39398.1 - 1.2e-07 31.9 0.2 0.0063 16.8 0.0 5.2 3 2 4 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM39398.1 - 2.3e-07 29.9 9.8 0.24 10.0 0.3 5.9 5 2 2 7 7 7 4 Nucleoporin Nup120/160 F-box_4 PF15966.5 GAM39398.1 - 0.0069 16.3 0.4 0.032 14.1 0.0 2.4 2 1 1 3 3 3 1 F-box WD40_like PF17005.5 GAM39398.1 - 0.035 13.4 0.1 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain PRANC PF09372.10 GAM39398.1 - 0.2 12.0 0.0 0.41 11.0 0.0 1.4 1 0 0 1 1 1 0 PRANC domain APG17 PF04108.12 GAM39399.1 - 1.2e-133 446.1 0.2 1.4e-133 445.9 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 FAP206 PF12018.8 GAM39399.1 - 0.017 14.6 0.0 0.16 11.4 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function SMC_N PF02463.19 GAM39400.1 - 2e-71 239.9 3.5 3.1e-71 239.3 3.5 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAM39400.1 - 2.4e-33 114.9 0.2 1.4e-32 112.5 0.0 2.5 3 0 0 3 3 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GAM39400.1 - 6.4e-19 68.9 5.8 1.7e-11 44.5 0.1 3.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAM39400.1 - 3.9e-18 66.7 2.5 3.9e-18 66.7 2.5 7.1 1 1 2 4 4 3 1 AAA domain AAA_15 PF13175.6 GAM39400.1 - 1.2e-14 54.8 58.1 1.7e-08 34.6 28.5 4.8 2 2 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 GAM39400.1 - 0.0052 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Attacin_C PF03769.15 GAM39400.1 - 0.043 14.1 0.6 0.28 11.4 0.1 2.5 2 0 0 2 2 2 0 Attacin, C-terminal region DUF211 PF02680.14 GAM39400.1 - 0.074 13.2 0.7 0.59 10.3 0.5 2.7 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 FtsK_SpoIIIE PF01580.18 GAM39400.1 - 0.22 10.8 0.0 0.22 10.8 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family ABC_tran PF00005.27 GAM39400.1 - 0.36 11.3 0.0 0.36 11.3 0.0 6.7 3 2 1 5 5 3 0 ABC transporter DUF87 PF01935.17 GAM39400.1 - 2.8 8.0 0.0 2.8 8.0 0.0 6.7 3 2 2 6 6 4 0 Helicase HerA, central domain APG6_N PF17675.1 GAM39400.1 - 8.2 7.0 121.7 1.5 9.4 20.9 8.9 3 2 4 8 8 8 0 Apg6 coiled-coil region RIO1 PF01163.22 GAM39401.1 - 1.5e-71 239.9 0.2 1.5e-71 239.9 0.2 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 GAM39401.1 - 0.0055 16.7 0.0 0.097 12.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAM39401.1 - 0.24 10.7 3.4 0.58 9.5 0.2 2.6 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFMR_assoc PF16596.5 GAM39401.1 - 1.1 9.7 5.1 3.9 7.9 5.1 1.9 1 0 0 1 1 1 0 Disordered region downstream of MFMR TSGP1 PF07771.11 GAM39401.1 - 1.3 9.2 7.4 4.2 7.6 7.4 1.9 1 0 0 1 1 1 0 Tick salivary peptide group 1 Flavin_Reduct PF01613.18 GAM39402.1 - 1.1e-15 58.0 0.0 1.7e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain XFP_N PF09364.10 GAM39403.1 - 1.5e-172 573.4 0.0 2e-172 573.1 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 GAM39403.1 - 1.7e-84 282.3 0.0 2.4e-84 281.8 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 GAM39403.1 - 2.7e-80 268.2 0.0 4.1e-80 267.6 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase ADH_zinc_N PF00107.26 GAM39404.1 - 4.9e-25 88.0 0.0 9.4e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DLH PF01738.18 GAM39404.1 - 1.4e-24 86.9 0.0 2.6e-24 86.0 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family ADH_zinc_N_2 PF13602.6 GAM39404.1 - 1.4e-11 45.6 0.0 3.5e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM39404.1 - 3.5e-08 33.3 0.2 9.3e-08 31.9 0.2 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Peptidase_S9 PF00326.21 GAM39404.1 - 0.00069 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 GAM39404.1 - 0.0015 18.5 0.0 0.028 14.3 0.0 2.4 2 1 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 GAM39404.1 - 0.002 17.8 0.1 0.64 9.6 0.0 2.6 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM39404.1 - 0.02 14.2 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 GAM39404.1 - 0.048 13.5 0.0 0.14 11.9 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold GDPD PF03009.17 GAM39405.1 - 1.4e-12 47.9 0.0 4.4e-07 29.9 0.0 2.2 1 1 1 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family LIM PF00412.22 GAM39406.1 - 3.2e-20 72.1 15.7 5.2e-12 45.8 2.8 3.0 3 0 0 3 3 3 2 LIM domain zf_UBZ PF18439.1 GAM39406.1 - 0.28 10.8 0.1 0.28 10.8 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger NAD_binding_5 PF07994.12 GAM39407.1 - 2.6e-144 480.6 0.0 3.1e-144 480.3 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 GAM39407.1 - 1.3e-45 154.2 0.5 2.7e-45 153.1 0.5 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase ADH_N PF08240.12 GAM39408.1 - 8e-26 90.1 1.3 2.1e-25 88.7 1.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM39408.1 - 1.5e-18 67.0 0.2 3.3e-18 65.9 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAM39408.1 - 0.0012 18.2 0.5 0.0022 17.3 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain LpxI_C PF06230.11 GAM39408.1 - 0.0034 17.2 1.3 0.0064 16.3 0.8 1.6 2 0 0 2 2 2 1 LpxI C-terminal domain Sacchrp_dh_NADP PF03435.18 GAM39408.1 - 0.0092 16.2 0.1 0.017 15.3 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 GAM39408.1 - 0.064 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-Tim10_DDP PF02953.15 GAM39409.1 - 1.7e-20 72.4 3.2 2.4e-20 71.9 3.2 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 GAM39409.1 - 0.003 17.3 2.8 0.0043 16.7 2.8 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) TAF6_C PF07571.13 GAM39409.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.3 1 1 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain RhoGAP PF00620.27 GAM39410.1 - 6e-39 133.3 0.0 1e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PIG-F PF06699.11 GAM39411.1 - 3.9e-72 242.2 4.5 4.6e-72 241.9 4.5 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_YMGG PF13441.6 GAM39411.1 - 0.062 13.1 7.8 0.48 10.2 7.8 2.1 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 GAM39411.1 - 0.071 13.1 6.3 1.7 8.7 0.9 2.2 2 0 0 2 2 2 0 Glycine zipper Caveolin PF01146.17 GAM39411.1 - 1.7 8.6 4.3 8.5 6.3 1.6 2.4 2 0 0 2 2 2 0 Caveolin Gly-zipper_OmpA PF13436.6 GAM39411.1 - 1.8 8.4 9.3 2.9 7.7 3.5 2.2 2 0 0 2 2 2 0 Glycine-zipper domain RRXRR PF14239.6 GAM39412.1 - 6.4 6.6 10.4 0.79 9.5 4.1 2.1 2 0 0 2 2 2 0 RRXRR protein NAD_binding_4 PF07993.12 GAM39414.1 - 3e-38 131.5 0.0 4.8e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAM39414.1 - 3.6e-22 78.6 0.0 9.2e-22 77.2 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 GAM39414.1 - 8.9e-11 41.7 0.0 1.5e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM39414.1 - 1.7e-06 27.3 0.0 3.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 GAM39414.1 - 0.00023 21.1 0.0 0.00055 19.9 0.0 1.6 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 GAM39414.1 - 0.00087 19.6 0.0 0.0025 18.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 GAM39414.1 - 0.033 13.6 0.0 0.073 12.5 0.0 1.6 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAM39414.1 - 0.038 13.1 0.0 0.088 11.9 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein tRNA-synt_1d PF00750.19 GAM39415.1 - 7.4e-103 344.1 7.5 6.8e-101 337.7 7.5 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 GAM39415.1 - 3e-27 95.2 0.6 3e-27 95.2 0.6 1.9 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 GAM39415.1 - 2.5e-07 31.2 0.7 6.1e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain YabA PF06156.13 GAM39415.1 - 0.016 15.9 1.8 0.026 15.2 0.8 1.8 2 0 0 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 GAM39415.1 - 0.19 11.5 3.7 0.5 10.2 3.7 1.7 1 0 0 1 1 1 0 Septum formation initiator PIP5K PF01504.18 GAM39416.1 - 1.4e-44 152.4 0.3 7.1e-43 146.8 0.3 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FAD_binding_6 PF00970.24 GAM39417.1 - 4.5e-33 113.5 0.0 7.1e-33 112.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GAM39417.1 - 3.6e-29 101.6 0.0 5.7e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAM39417.1 - 2.4e-06 27.7 0.0 0.00016 21.8 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 GAM39417.1 - 0.022 15.0 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain PuR_N PF09182.10 GAM39417.1 - 0.51 10.3 1.7 15 5.6 0.0 2.8 3 0 0 3 3 3 0 Bacterial purine repressor, N-terminal DUF3605 PF12239.8 GAM39418.1 - 6e-60 202.0 0.3 7.3e-60 201.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) MFS_1 PF07690.16 GAM39419.1 - 2.7e-33 115.4 26.7 2.7e-33 115.4 26.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily LapA_dom PF06305.11 GAM39419.1 - 0.039 13.8 1.7 0.77 9.6 0.0 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF373 PF04123.13 GAM39419.1 - 0.11 12.0 0.8 0.25 10.7 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Glyco_hydro_72 PF03198.14 GAM39420.1 - 8.3e-137 455.6 5.1 9.8e-137 455.4 5.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 GAM39420.1 - 3.4e-07 30.0 0.2 2.3e-06 27.3 0.2 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1373 PF07117.11 GAM39420.1 - 0.0052 16.8 2.7 0.0086 16.1 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1373) Med3 PF11593.8 GAM39420.1 - 3.1 6.9 5.6 4.6 6.3 3.5 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Fungal_trans PF04082.18 GAM39421.1 - 1.6e-28 99.5 0.0 3.5e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM39421.1 - 0.00093 19.3 14.8 0.0015 18.6 14.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Choline_transpo PF04515.12 GAM39422.1 - 2.4e-81 273.5 26.4 2.4e-81 273.5 26.4 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter PBP PF01161.20 GAM39423.1 - 1.2e-11 45.0 0.0 1.5e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SH3_9 PF14604.6 GAM39424.1 - 7.1e-25 86.6 0.3 4.8e-14 51.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 GAM39424.1 - 4.1e-24 84.7 1.1 1e-23 83.4 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 GAM39424.1 - 1.1e-17 63.4 0.1 1.9e-08 33.8 0.0 2.6 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 GAM39424.1 - 4.8e-15 55.2 5.3 7.6e-15 54.5 5.3 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_10 PF17902.1 GAM39424.1 - 3.3e-05 23.8 0.0 0.23 11.6 0.0 2.9 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 GAM39424.1 - 6.5e-05 22.5 0.1 0.43 10.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain C1_2 PF03107.16 GAM39424.1 - 0.0098 16.2 4.1 0.018 15.3 4.1 1.4 1 0 0 1 1 1 1 C1 domain SH3_3 PF08239.11 GAM39424.1 - 0.13 12.6 0.2 2.5 8.4 0.0 2.6 2 0 0 2 2 2 0 Bacterial SH3 domain GrpE PF01025.19 GAM39424.1 - 3.5 7.3 15.3 1.4 8.6 2.7 2.7 2 0 0 2 2 2 0 GrpE UvrA_DNA-bind PF17755.1 GAM39424.1 - 5.6 7.4 6.9 3.1 8.2 0.6 3.0 3 1 0 3 3 3 0 UvrA DNA-binding domain DEAD PF00270.29 GAM39425.1 - 1.2e-30 106.5 0.2 3.9e-30 104.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM39425.1 - 8e-23 80.9 0.0 2.3e-22 79.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 GAM39425.1 - 0.017 14.8 0.1 0.089 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain CMS1 PF14617.6 GAM39425.1 - 0.022 14.1 0.1 0.051 12.9 0.1 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit tRNA-synt_1b PF00579.25 GAM39425.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) UPRTase PF14681.6 GAM39426.1 - 1.5e-52 178.0 0.1 4.1e-47 160.3 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 GAM39426.1 - 6.8e-05 22.4 0.0 9.7e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Peptidase_M30 PF10460.9 GAM39426.1 - 0.1 11.5 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase M30 GTP_CH_N PF12471.8 GAM39427.1 - 9.9e-89 296.2 0.0 1.5e-88 295.6 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal CAP59_mtransfer PF11735.8 GAM39427.1 - 1.3e-71 241.1 0.0 2.1e-71 240.4 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 GTP_cyclohydro2 PF00925.20 GAM39427.1 - 5.9e-18 65.0 0.0 1.3e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF996 PF06195.13 GAM39427.1 - 0.085 13.1 0.1 0.18 12.1 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF996) Clat_adaptor_s PF01217.20 GAM39428.1 - 5.2e-51 172.3 1.2 7.9e-51 171.7 1.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.10 GAM39428.1 - 1.1e-45 155.9 6.3 1.9e-27 96.6 0.4 2.2 1 1 1 2 2 2 2 Maf1 regulator DUF1694 PF07997.11 GAM39428.1 - 0.077 13.1 0.0 0.4 10.8 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1694) Sugar_tr PF00083.24 GAM39429.1 - 1.3e-109 367.0 19.1 1.6e-109 366.7 19.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM39429.1 - 1.4e-23 83.4 26.5 1.4e-23 83.4 26.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM39429.1 - 6e-05 21.7 0.4 0.0001 20.9 0.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 GAM39429.1 - 0.001 17.7 14.9 0.03 12.9 4.3 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein GAF_2 PF13185.6 GAM39430.1 - 4.6e-13 49.6 0.0 1.1e-12 48.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 GAM39430.1 - 1.7e-08 35.1 0.2 4.1e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 GAF domain bZIP_2 PF07716.15 GAM39430.1 - 3e-06 27.2 6.2 3e-06 27.2 6.2 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 GAM39430.1 - 7.3e-06 26.0 6.4 1.6e-05 24.9 6.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor GAF_3 PF13492.6 GAM39430.1 - 0.039 14.3 0.0 0.086 13.2 0.0 1.6 1 0 0 1 1 1 0 GAF domain DivIC PF04977.15 GAM39430.1 - 0.043 13.6 0.8 0.1 12.4 0.8 1.6 1 0 0 1 1 1 0 Septum formation initiator NAD_kinase PF01513.21 GAM39431.1 - 3e-81 272.8 0.0 4.3e-81 272.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.21 GAM39432.1 - 8.3e-05 23.1 0.0 0.00018 22.0 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 DUF2567 PF10821.8 GAM39433.1 - 0.00039 20.6 0.1 0.00066 19.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2567) FSH1 PF03959.13 GAM39434.1 - 1.2e-25 90.5 0.0 3.2e-25 89.1 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) MAAL_C PF07476.11 GAM39434.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus NAD_binding_6 PF08030.12 GAM39435.1 - 1.5e-05 25.2 0.0 2.4e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF2014 PF09427.10 GAM39436.1 - 1.4e-98 329.5 0.1 2e-98 329.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 GAM39436.1 - 1.6e-17 63.2 0.4 7.1e-17 61.1 0.3 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Fungal_trans PF04082.18 GAM39437.1 - 1e-26 93.6 0.7 2.2e-26 92.5 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM39437.1 - 0.037 14.1 2.4 0.075 13.2 2.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Redoxin PF08534.10 GAM39438.1 - 1.9e-27 95.8 0.0 2.9e-27 95.2 0.0 1.3 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAM39438.1 - 1.6e-07 31.2 0.0 2.9e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Filament PF00038.21 GAM39439.1 - 1.2e-06 28.4 20.0 1.2e-06 28.4 20.0 3.8 2 1 1 3 3 3 2 Intermediate filament protein MscS_porin PF12795.7 GAM39439.1 - 3e-05 23.7 35.0 3e-05 23.7 35.0 4.1 2 2 3 5 5 4 2 Mechanosensitive ion channel porin domain DUF5082 PF16888.5 GAM39439.1 - 0.0028 17.9 14.9 0.0028 17.9 14.9 4.6 2 1 2 4 4 3 2 Domain of unknown function (DUF5082) KASH_CCD PF14662.6 GAM39439.1 - 0.0033 17.3 60.1 0.23 11.3 26.9 3.3 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 GAM39439.1 - 0.0042 16.5 13.5 0.0042 16.5 13.5 4.0 1 1 2 4 4 3 1 Domain of unknown function (DUF4407) ADIP PF11559.8 GAM39439.1 - 0.0045 17.1 7.0 0.0045 17.1 7.0 6.1 5 2 2 7 7 6 1 Afadin- and alpha -actinin-Binding APG17 PF04108.12 GAM39439.1 - 0.0046 16.1 16.3 0.0046 16.1 16.3 3.2 1 1 1 3 3 3 1 Autophagy protein Apg17 BLOC1_2 PF10046.9 GAM39439.1 - 0.0052 17.1 6.1 0.0052 17.1 6.1 4.3 3 1 1 5 5 4 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 GAM39439.1 - 0.017 15.4 18.5 0.017 15.4 18.5 5.6 2 2 3 5 5 4 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 GAM39439.1 - 1.4 9.3 47.0 1.1 9.7 1.4 7.2 4 2 3 7 7 7 0 Flagella accessory protein C (FlaC) Trypan_PARP PF05887.11 GAM39439.1 - 1.6 8.7 21.5 5.8 6.9 21.5 1.9 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4988 PF16378.5 GAM39439.1 - 2.4 7.8 10.6 18 4.9 0.5 3.9 2 1 0 3 3 3 0 Domain of unknown function NPV_P10 PF05531.12 GAM39439.1 - 2.8 8.5 21.9 9.7 6.7 1.0 4.9 2 1 3 5 5 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 GAM39439.1 - 6.6 6.8 28.3 0.26 11.4 1.1 4.0 1 1 0 3 3 3 0 Protein of unknown function (DUF1664) Cupin_2 PF07883.11 GAM39440.1 - 1.1e-25 89.1 0.2 2.7e-16 59.0 0.1 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 GAM39440.1 - 1.2e-06 28.5 0.1 0.00047 20.1 0.1 2.4 2 1 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 GAM39440.1 - 6.9e-05 22.5 0.0 0.055 13.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) DMSP_lyase PF16867.5 GAM39440.1 - 0.003 17.2 0.1 0.0059 16.3 0.1 1.5 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase CENP-C_C PF11699.8 GAM39440.1 - 0.0041 17.3 0.0 0.18 12.0 0.0 2.2 2 0 0 2 2 2 1 Mif2/CENP-C like ARD PF03079.14 GAM39440.1 - 0.0056 16.9 0.1 0.024 14.8 0.0 1.9 2 0 0 2 2 2 1 ARD/ARD' family FAD_binding_3 PF01494.19 GAM39441.1 - 4.9e-20 72.1 0.0 6.5e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM39441.1 - 1.2e-08 34.5 0.1 0.00022 20.6 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM39441.1 - 1.2e-07 31.8 0.5 4.3e-07 30.1 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM39441.1 - 5e-06 26.3 3.5 0.01 15.5 2.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM39441.1 - 1.3e-05 24.5 1.1 3e-05 23.3 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 GAM39441.1 - 0.00097 18.5 0.3 0.0061 15.9 0.1 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 GAM39441.1 - 0.002 17.5 2.2 0.0032 16.9 2.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM39441.1 - 0.0027 18.2 0.0 0.056 14.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM39441.1 - 0.0051 16.8 0.5 0.028 14.4 0.5 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 GAM39441.1 - 0.0053 15.5 0.2 0.011 14.5 0.1 1.4 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 GAM39441.1 - 0.011 14.6 0.7 2.3 7.0 0.1 2.5 2 1 1 3 3 3 0 Tryptophan halogenase GIDA PF01134.22 GAM39441.1 - 0.016 14.3 0.5 0.03 13.4 0.5 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GAM39441.1 - 0.017 14.2 0.0 0.037 13.1 0.0 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 GAM39441.1 - 0.046 12.9 0.6 0.21 10.8 0.3 1.9 2 0 0 2 2 2 0 Thi4 family MCRA PF06100.11 GAM39441.1 - 0.12 11.2 0.1 0.17 10.6 0.1 1.1 1 0 0 1 1 1 0 MCRA family AsmA_2 PF13502.6 GAM39441.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AsmA-like C-terminal region DUF211 PF02680.14 GAM39441.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Aldedh PF00171.22 GAM39442.1 - 3.2e-111 372.1 0.0 3.8e-111 371.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RPE65 PF03055.15 GAM39443.1 - 6.4e-92 309.1 0.0 1.4e-46 159.7 0.0 2.0 1 1 1 2 2 2 2 Retinal pigment epithelial membrane protein FAA_hydrolase PF01557.18 GAM39444.1 - 1.4e-61 207.9 0.0 1.8e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.16 GAM39445.1 - 3.2e-40 138.1 23.0 3.2e-40 138.1 23.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM39445.1 - 1.8e-13 50.2 6.3 1.8e-13 50.2 6.3 3.1 2 1 1 4 4 4 1 Sugar (and other) transporter MFS_4 PF06779.14 GAM39445.1 - 5.8e-06 25.8 6.9 5.8e-06 25.8 6.9 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF5090 PF17009.5 GAM39445.1 - 7.3 6.5 13.2 2.2 8.2 0.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5090) PNP_UDP_1 PF01048.20 GAM39446.1 - 3e-05 23.4 0.0 5.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily COPIIcoated_ERV PF07970.12 GAM39447.1 - 1.5e-37 129.6 0.2 2.7e-37 128.8 0.2 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAM39447.1 - 4.1e-24 84.7 0.0 7.3e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.25 GAM39448.1 - 2.5e-54 184.4 0.0 3.7e-54 183.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM39448.1 - 2.7e-20 72.8 0.0 4.5e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM39448.1 - 0.084 12.8 0.0 0.7 9.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 GAM39448.1 - 0.14 12.3 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 ABC1 family Choline_kinase PF01633.20 GAM39448.1 - 0.17 11.5 0.4 0.35 10.4 0.4 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pex24p PF06398.11 GAM39449.1 - 5.3e-83 279.0 0.0 6.5e-83 278.7 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 GAM39449.1 - 1.4 7.2 5.0 0.62 8.4 0.7 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3292) Nop16 PF09420.10 GAM39450.1 - 1.6e-59 201.5 9.2 1.8e-59 201.3 9.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zip PF02535.22 GAM39451.1 - 1.6e-59 201.8 4.9 3.8e-59 200.6 4.9 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter DUF456 PF04306.13 GAM39451.1 - 0.77 10.0 15.5 4.1 7.7 7.2 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF456) Anp1 PF03452.14 GAM39453.1 - 1.5e-105 352.4 0.0 2e-105 351.9 0.0 1.2 1 0 0 1 1 1 1 Anp1 Mito_carr PF00153.27 GAM39453.1 - 1.2e-52 175.8 0.2 9.3e-18 64.0 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Glycos_transf_2 PF00535.26 GAM39453.1 - 0.084 12.7 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 RdRP_3 PF00998.23 GAM39454.1 - 0.028 13.1 0.0 0.059 12.1 0.0 1.5 2 0 0 2 2 2 0 Viral RNA dependent RNA polymerase DUF2009 PF09418.10 GAM39454.1 - 0.061 12.4 0.0 0.063 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) DUF445 PF04286.12 GAM39454.1 - 0.075 12.8 0.7 0.086 12.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Peptidase_A4 PF01828.17 GAM39455.1 - 1.7e-62 210.6 18.9 2.1e-62 210.3 18.9 1.1 1 0 0 1 1 1 1 Peptidase A4 family Methyltransf_2 PF00891.18 GAM39457.1 - 8.3e-29 100.4 0.1 1.6e-28 99.4 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 GAM39457.1 - 0.0014 18.5 0.0 0.0038 17.2 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 GAM39457.1 - 0.0093 16.0 0.0 0.35 10.9 0.0 3.4 3 1 0 3 3 3 1 Dimerisation domain Methyltransf_25 PF13649.6 GAM39457.1 - 0.013 16.2 0.0 0.036 14.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAM39457.1 - 0.038 13.8 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Rrf2 PF02082.20 GAM39457.1 - 0.046 14.1 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator DHDPS PF00701.22 GAM39458.1 - 4.7e-40 137.1 0.0 6.5e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Kdo PF06293.14 GAM39459.1 - 7.8e-13 48.2 0.0 7e-12 45.1 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM39459.1 - 2.7e-08 34.0 0.0 0.0048 16.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 GAM39459.1 - 1.1e-07 31.5 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 GAM39459.1 - 0.0003 20.4 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 GAM39459.1 - 0.00082 19.0 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 GAM39459.1 - 0.018 14.4 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF1679 PF07914.11 GAM39459.1 - 0.094 11.5 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 GAM39459.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Aldo_ket_red PF00248.21 GAM39460.1 - 1.6e-12 47.3 0.0 2.3e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3445 PF11927.8 GAM39461.1 - 8.6e-77 257.8 0.2 8.6e-77 257.8 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3445) Homoserine_dh PF00742.19 GAM39462.1 - 9.5e-53 178.7 0.0 1.2e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 GAM39462.1 - 1.6e-14 54.6 0.0 3.6e-14 53.4 0.0 1.6 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DEC-1_N PF04625.13 GAM39462.1 - 0.15 11.0 3.2 11 4.9 0.0 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region DUF4078 PF13300.6 GAM39463.1 - 6.6e-27 93.7 13.9 6.6e-27 93.7 13.9 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) Lactamase_B_2 PF12706.7 GAM39464.1 - 2.2e-18 66.5 0.1 2.9e-18 66.1 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAM39464.1 - 9.6e-13 48.3 0.0 2.2e-12 47.2 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAM39464.1 - 0.00022 21.3 0.8 0.00082 19.4 0.8 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_transf_4 PF13439.6 GAM39464.1 - 0.054 13.5 0.1 0.088 12.8 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Lactamase_B_6 PF16661.5 GAM39464.1 - 0.16 11.4 0.0 0.34 10.3 0.0 1.5 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily domain Peptidase_S10 PF00450.22 GAM39465.1 - 1.3e-93 314.7 0.1 1.6e-93 314.4 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase M20_dimer PF07687.14 GAM39466.1 - 1.6e-10 40.8 0.1 3.3e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 GAM39466.1 - 1e-07 31.9 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF982 PF06169.12 GAM39466.1 - 0.12 12.4 0.4 3.4 7.8 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF982) MFS_1 PF07690.16 GAM39467.1 - 1.8e-29 102.8 32.9 1.2e-27 96.8 32.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM39467.1 - 0.00037 19.9 1.9 0.00037 19.9 1.9 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB M20_dimer PF07687.14 GAM39468.1 - 5.2e-08 32.8 0.0 1.3e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 GAM39468.1 - 0.00019 21.2 0.0 0.0003 20.6 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 GAM39470.1 - 7.4e-24 83.6 17.2 1.5e-06 28.8 0.1 9.6 11 0 0 11 11 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM39470.1 - 4.4e-17 62.2 2.7 0.00019 21.6 0.0 7.4 2 1 6 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 GAM39470.1 - 1.4e-07 30.9 0.0 0.00017 20.8 0.0 3.4 3 1 1 4 4 4 2 Coatomer WD associated region Ge1_WD40 PF16529.5 GAM39470.1 - 5.5e-07 28.9 0.7 0.16 10.9 0.1 4.3 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 GAM39470.1 - 3.8e-05 23.4 1.8 0.0023 17.6 0.6 3.5 2 1 1 3 3 3 1 PQQ-like domain PALB2_WD40 PF16756.5 GAM39470.1 - 4.9e-05 22.4 0.4 0.41 9.5 0.0 4.1 2 2 1 4 4 4 2 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 GAM39470.1 - 5.9e-05 22.9 3.7 3.6 7.7 0.0 6.3 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 GAM39470.1 - 0.015 13.9 2.6 21 3.6 0.0 4.7 2 2 2 5 5 5 0 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 GAM39470.1 - 0.038 13.7 1.9 1.6e+02 2.1 0.0 6.0 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature HPS3_N PF14761.6 GAM39470.1 - 0.082 12.4 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 FCP1_C PF09309.10 GAM39470.1 - 0.16 11.9 0.0 35 4.1 0.0 2.9 2 1 1 3 3 3 0 FCP1, C-terminal STE2 PF02116.15 GAM39471.1 - 6.7e-93 311.0 26.0 8.2e-93 310.7 26.0 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Fungal_trans_2 PF11951.8 GAM39472.1 - 1e-07 31.1 1.3 1.5e-07 30.6 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 GAM39473.1 - 7.2e-57 192.3 10.2 7.2e-57 192.3 10.2 1.5 2 0 0 2 2 2 1 RTA1 like protein UEV PF05743.13 GAM39474.1 - 1.3e-37 128.3 0.1 2.5e-37 127.4 0.1 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 GAM39474.1 - 7.5e-22 77.1 0.2 1.9e-21 75.8 0.0 1.8 2 0 0 2 2 2 1 Vps23 core domain DUF720 PF05302.11 GAM39474.1 - 0.015 15.2 5.4 0.034 14.0 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF720) WEMBL PF05701.11 GAM39474.1 - 0.064 12.0 0.3 0.088 11.5 0.3 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light FliJ PF02050.16 GAM39474.1 - 0.5 10.6 3.5 0.96 9.7 3.5 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein ATG16 PF08614.11 GAM39474.1 - 6.1 7.0 7.4 0.82 9.9 3.0 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) MFS_1 PF07690.16 GAM39475.1 - 1.1e-32 113.4 48.9 1.4e-32 113.0 42.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BAR PF03114.18 GAM39477.1 - 1.8e-68 230.7 4.2 2.5e-68 230.3 4.2 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 GAM39477.1 - 1.5e-14 53.3 0.1 3e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAM39477.1 - 2.2e-12 46.6 0.1 3.8e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAM39477.1 - 2e-09 37.0 0.0 5e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 GAM39477.1 - 0.0039 16.8 3.7 0.28 10.7 2.2 2.3 2 0 0 2 2 2 2 Vps5 C terminal like CT_C_D PF02682.16 GAM39477.1 - 0.12 12.1 0.3 0.25 11.0 0.3 1.5 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D BAR_3 PF16746.5 GAM39477.1 - 1.1 9.0 9.4 4.5 6.9 9.1 2.2 1 1 0 1 1 1 0 BAR domain of APPL family TMPIT PF07851.13 GAM39477.1 - 1.9 7.6 7.3 2.6 7.2 0.1 2.2 1 1 1 2 2 2 0 TMPIT-like protein BRE1 PF08647.11 GAM39477.1 - 2 8.6 17.1 2.6 8.2 0.2 3.4 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF4375 PF14300.6 GAM39477.1 - 3.5 7.9 7.2 1.2 9.5 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) CorA PF01544.18 GAM39477.1 - 4.3 6.6 9.2 19 4.5 0.0 2.6 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Aminotran_5 PF00266.19 GAM39478.1 - 5.4e-94 315.2 0.0 6.5e-94 314.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAM39478.1 - 4.6e-05 22.9 0.0 7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GAM39478.1 - 0.0014 18.0 0.1 0.0041 16.5 0.1 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 GAM39478.1 - 0.094 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain adh_short PF00106.25 GAM39479.1 - 9e-10 38.3 0.0 1.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM39479.1 - 5.7e-09 35.9 0.1 9.4e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NACHT PF05729.12 GAM39479.1 - 6.2e-06 26.2 0.0 4.3e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 NACHT domain TPR_10 PF13374.6 GAM39479.1 - 8.7e-06 25.4 0.0 3.1e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Ses_B PF17046.5 GAM39479.1 - 9.8e-05 22.2 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein NB-ARC PF00931.22 GAM39479.1 - 0.00024 20.4 0.0 0.42 9.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.6 GAM39479.1 - 0.0012 19.1 0.0 0.0058 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAM39479.1 - 0.0082 15.7 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain 2-Hacid_dh_C PF02826.19 GAM39479.1 - 0.021 14.2 0.1 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPR_12 PF13424.6 GAM39479.1 - 0.079 13.3 0.0 0.37 11.1 0.0 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat F420_oxidored PF03807.17 GAM39479.1 - 0.16 12.6 0.0 0.62 10.7 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 GAM39479.1 - 0.17 11.3 0.0 0.42 10.0 0.0 1.7 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family IDO PF01231.18 GAM39480.1 - 4.5e-163 543.1 0.0 5.1e-163 542.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 GAM39480.1 - 0.0078 15.0 0.1 0.04 12.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1864) CsbD PF05532.12 GAM39481.1 - 1.6e-12 47.1 6.9 2.7e-10 40.0 1.7 2.8 3 0 0 3 3 3 2 CsbD-like Grg1 PF11034.8 GAM39481.1 - 0.46 10.7 0.1 0.46 10.7 0.1 2.6 2 1 0 2 2 2 0 Glucose-repressible protein Grg1 DUF702 PF05142.12 GAM39482.1 - 0.35 11.3 1.3 1.5 9.3 0.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF702) ADH_zinc_N_2 PF13602.6 GAM39483.1 - 3.6e-23 83.1 0.0 5.9e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAM39483.1 - 6.8e-15 55.2 0.0 1.1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 GAM39483.1 - 0.01 15.6 0.1 0.047 13.4 0.0 2.1 3 0 0 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Epimerase PF01370.21 GAM39483.1 - 0.026 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAM39483.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain zf-C2H2 PF00096.26 GAM39484.1 - 0.021 15.2 3.3 1.6 9.3 0.0 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type KTI12 PF08433.10 GAM39485.1 - 7.1e-62 209.3 0.0 2.6e-60 204.2 0.0 2.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 GAM39485.1 - 0.073 13.2 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF463 PF04317.12 GAM39487.1 - 0.031 13.2 2.1 0.041 12.8 2.1 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 Peptidase_S64 PF08192.11 GAM39487.1 - 0.039 12.4 5.1 0.037 12.5 5.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 SprA-related PF12118.8 GAM39487.1 - 1.6 7.8 18.4 1.6 7.8 17.1 1.5 1 1 0 2 2 2 0 SprA-related family Dicty_REP PF05086.12 GAM39487.1 - 2.5 6.0 7.5 2.7 5.9 7.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MBD_C PF14048.6 GAM39487.1 - 5.6 7.7 10.9 3 8.6 8.6 1.9 1 1 1 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 Methyltransf_16 PF10294.9 GAM39488.1 - 3.8e-16 59.3 0.0 5.5e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GAM39488.1 - 0.00027 20.8 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAM39488.1 - 0.16 11.3 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_C14 PF00656.22 GAM39489.1 - 8.8e-60 202.7 0.0 1.1e-59 202.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Nitroreductase PF00881.24 GAM39490.1 - 5.5e-12 46.1 0.0 7.2e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family F-box PF00646.33 GAM39491.1 - 1e-05 25.2 0.0 2.7e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAM39491.1 - 0.00091 19.1 0.1 0.0027 17.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 GAM39491.1 - 0.0047 16.8 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 F-box DUF2236 PF09995.9 GAM39494.1 - 1.4e-44 153.0 0.7 1.8e-44 152.6 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) RACo_linker PF17650.1 GAM39494.1 - 0.046 13.6 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 RACo linker region DUF3712 PF12505.8 GAM39495.1 - 1.6e-27 96.3 3.3 1.8e-27 96.1 0.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) WD40 PF00400.32 GAM39496.1 - 3.4e-53 176.4 22.2 2e-09 37.9 0.3 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM39496.1 - 1.1e-18 67.3 0.1 0.00012 22.3 0.0 6.6 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM39496.1 - 2.4e-07 30.4 0.0 0.084 12.2 0.0 3.8 2 1 2 4 4 4 3 WD40-like domain Cytochrom_D1 PF02239.16 GAM39496.1 - 9.3e-06 24.4 0.2 0.0004 19.0 0.1 2.6 1 1 3 4 4 4 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 GAM39496.1 - 0.00042 19.4 0.1 0.49 9.3 0.0 4.2 2 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAM39496.1 - 0.0011 17.7 0.0 4.9 5.7 0.0 3.5 2 2 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 GAM39496.1 - 0.022 14.7 0.0 4.4 7.1 0.0 3.3 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF5046 PF16465.5 GAM39496.1 - 0.046 13.2 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) VID27 PF08553.10 GAM39496.1 - 0.052 12.6 0.0 0.32 10.0 0.0 2.2 2 1 1 3 3 3 0 VID27 C-terminal WD40-like domain PNP_UDP_1 PF01048.20 GAM39497.1 - 1.6e-13 50.5 1.3 3.6e-13 49.3 1.3 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily NS3_envE PF02723.14 GAM39497.1 - 0.12 12.4 0.1 5.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E Egg_lysin PF01303.17 GAM39497.1 - 0.13 12.5 0.1 3.9 7.7 0.2 2.6 2 0 0 2 2 2 0 Egg lysin (Sperm-lysin) Fungal_trans PF04082.18 GAM39498.1 - 2.1e-14 53.2 0.1 6.1e-14 51.7 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ion_trans_2 PF07885.16 GAM39499.1 - 6.2e-27 93.4 25.8 2.4e-15 56.2 6.9 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 GAM39499.1 - 0.0059 15.9 18.9 0.027 13.7 2.3 3.3 3 0 0 3 3 3 3 Ion transport protein FA_desaturase PF00487.24 GAM39499.1 - 0.86 9.4 8.5 7.9 6.2 0.0 2.9 2 1 0 2 2 2 0 Fatty acid desaturase DUF5453 PF17534.2 GAM39499.1 - 0.96 9.4 5.9 0.31 11.0 2.2 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5453) Palm_thioest PF02089.15 GAM39500.1 - 9e-82 274.5 0.0 1.1e-81 274.3 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 GAM39500.1 - 0.0017 17.8 0.0 0.0033 16.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 GAM39500.1 - 0.062 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAM39500.1 - 0.069 13.0 0.2 7.2 6.3 0.1 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase MFS_1 PF07690.16 GAM39501.1 - 2.2e-44 151.9 43.6 2.2e-44 151.9 43.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF997 PF06196.12 GAM39501.1 - 2.4 8.2 9.6 0.18 11.9 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF997) Fungal_trans PF04082.18 GAM39502.1 - 7.9e-10 38.2 0.1 1.5e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box-like PF12937.7 GAM39503.1 - 0.0021 17.9 0.1 0.0046 16.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like PRANC PF09372.10 GAM39503.1 - 0.0046 17.3 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 PRANC domain F-box PF00646.33 GAM39503.1 - 0.033 14.1 0.1 0.068 13.1 0.1 1.5 1 0 0 1 1 1 0 F-box domain adh_short_C2 PF13561.6 GAM39504.1 - 1.1e-30 107.0 0.0 1.4e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM39504.1 - 9.4e-27 93.7 0.0 1.3e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM39504.1 - 3.8e-10 40.0 0.0 9.6e-10 38.7 0.0 1.6 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GAM39504.1 - 0.011 14.9 0.1 0.02 14.0 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein CENP-L PF13092.6 GAM39505.1 - 9.4e-41 139.7 0.7 1.5e-40 139.1 0.7 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 T6PP_N PF18572.1 GAM39505.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Sulfate_transp PF00916.20 GAM39506.1 - 1.1e-70 238.3 10.1 3.2e-70 236.8 10.1 1.7 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAM39506.1 - 6.8e-18 64.4 0.0 1.1e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 GAM39506.1 - 7.4e-05 23.0 0.0 0.00018 21.8 0.0 1.7 1 1 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAM39506.1 - 0.0011 19.4 4.6 0.0011 19.4 4.6 2.3 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily S1 PF00575.23 GAM39507.1 - 2.2e-10 40.7 0.4 4.8e-10 39.6 0.4 1.5 1 0 0 1 1 1 1 S1 RNA binding domain PKD_channel PF08016.12 GAM39507.1 - 2.2e-08 33.3 19.4 6.7e-08 31.6 19.4 1.8 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 GAM39507.1 - 3.1e-05 23.3 29.7 0.0025 17.1 29.7 2.2 1 1 0 1 1 1 1 Ion transport protein Fungal_trans_2 PF11951.8 GAM39508.1 - 5.4e-07 28.7 0.3 7.4e-07 28.3 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_2 PF00891.18 GAM39509.1 - 3.9e-22 78.6 0.0 6.3e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 GAM39509.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Acyltransferase PF01553.21 GAM39510.1 - 8.5e-09 35.1 0.0 1.4e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase DUF2537 PF10801.8 GAM39510.1 - 0.31 11.3 3.8 0.79 10.0 3.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2537) FMN_dh PF01070.18 GAM39511.1 - 5.9e-116 387.3 0.0 7.4e-116 387.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 GAM39511.1 - 2.1e-19 69.4 0.0 5.4e-19 68.1 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 GAM39511.1 - 1.3e-07 31.1 0.0 2.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 GAM39511.1 - 1.4e-05 24.2 4.1 0.00019 20.5 0.9 2.5 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain Dus PF01207.17 GAM39511.1 - 0.00026 20.2 0.1 0.00094 18.4 0.0 1.9 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 GAM39511.1 - 0.0004 19.9 0.2 1 8.8 0.0 2.8 3 0 0 3 3 3 2 Histidine biosynthesis protein ThiG PF05690.14 GAM39511.1 - 0.0061 15.9 0.1 2.8 7.2 0.0 2.6 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 GAM39511.1 - 0.011 15.2 0.6 0.029 13.7 0.3 1.7 1 1 1 2 2 2 0 Nitronate monooxygenase DHO_dh PF01180.21 GAM39511.1 - 0.13 11.5 0.1 0.37 10.0 0.0 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase EF-G-binding_N PF07299.11 GAM39511.1 - 0.14 12.7 0.1 0.51 10.9 0.0 1.9 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Sugar_tr PF00083.24 GAM39512.1 - 5.1e-102 342.1 28.3 5.9e-102 341.9 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM39512.1 - 1.7e-21 76.6 25.7 1.7e-21 76.6 25.7 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily FAM180 PF15173.6 GAM39513.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 FAM180 family RSN1_7TM PF02714.15 GAM39514.1 - 5.4e-78 262.1 23.8 5.4e-78 262.1 23.8 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 GAM39514.1 - 4.6e-41 141.0 0.0 6.7e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 GAM39514.1 - 4.3e-39 133.8 2.6 4.3e-39 133.8 2.6 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Endosulfine PF04667.17 GAM39514.1 - 0.18 12.0 0.0 0.56 10.4 0.0 1.8 2 0 0 2 2 2 0 cAMP-regulated phosphoprotein/endosulfine conserved region UCH PF00443.29 GAM39515.1 - 1.8e-34 119.4 0.0 1.3e-29 103.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM39515.1 - 2.5e-09 37.2 0.3 5.8e-06 26.1 0.1 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase SOG2 PF10428.9 GAM39515.1 - 0.048 12.9 11.4 0.073 12.3 11.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Cytochrome_C7 PF14522.6 GAM39515.1 - 1.2 9.2 3.9 0.95 9.5 0.4 2.6 3 0 0 3 3 3 0 Cytochrome c7 and related cytochrome c CpXC PF14353.6 GAM39515.1 - 3.3 7.8 5.4 14 5.8 1.6 2.8 2 1 1 3 3 3 0 CpXC protein F_bP_aldolase PF01116.20 GAM39516.1 - 1.5e-92 310.1 0.0 1.7e-92 309.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II AlaDh_PNT_N PF05222.15 GAM39517.1 - 2.4e-31 108.9 0.0 4.4e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 GAM39517.1 - 2.5e-07 30.2 0.3 1.8e-05 24.2 0.0 2.8 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain CUE PF02845.16 GAM39519.1 - 5.9e-09 35.5 0.0 9.2e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 CUE domain Oxysterol_BP PF01237.18 GAM39520.1 - 5e-63 213.2 5.1 7e-61 206.1 5.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein MFS_1 PF07690.16 GAM39521.1 - 1.9e-44 152.0 34.5 1.9e-44 152.0 34.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ABC_tran PF00005.27 GAM39522.1 - 9.9e-49 165.4 0.1 8.1e-29 100.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAM39522.1 - 3.1e-43 148.4 20.3 1.2e-23 84.2 5.4 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 GAM39522.1 - 2.4e-09 36.9 3.6 0.046 13.2 1.3 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAM39522.1 - 1.5e-07 31.5 5.0 0.49 10.2 0.6 4.5 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM39522.1 - 4.6e-05 23.1 0.8 0.27 11.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 GAM39522.1 - 0.0002 20.5 2.1 0.049 12.7 0.1 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_22 PF13401.6 GAM39522.1 - 0.00027 21.2 1.2 2.1 8.6 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 GAM39522.1 - 0.00047 20.7 8.9 0.0055 17.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 GAM39522.1 - 0.00052 20.4 0.6 0.21 12.0 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 GAM39522.1 - 0.001 18.7 0.2 0.38 10.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 GAM39522.1 - 0.0013 18.8 1.7 0.43 10.7 0.1 3.5 4 0 0 4 4 4 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAM39522.1 - 0.0047 17.0 1.7 0.093 12.8 0.0 3.0 3 0 0 3 3 3 1 Dynamin family Adeno_IVa2 PF02456.15 GAM39522.1 - 0.0048 15.8 0.1 0.41 9.4 0.0 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein SbcCD_C PF13558.6 GAM39522.1 - 0.0072 16.5 0.6 4.5 7.6 0.0 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 GAM39522.1 - 0.0072 16.2 0.3 1.1 9.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase DEAD PF00270.29 GAM39522.1 - 0.0088 15.8 0.2 2.4 7.9 0.0 3.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Roc PF08477.13 GAM39522.1 - 0.017 15.4 0.1 4.5 7.5 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 GAM39522.1 - 0.026 14.6 2.7 0.33 11.0 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Viral_helicase1 PF01443.18 GAM39522.1 - 0.031 14.0 0.0 2.1 8.0 0.0 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase ABC_ATPase PF09818.9 GAM39522.1 - 0.036 12.9 0.1 0.55 9.0 0.0 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.18 GAM39522.1 - 0.049 13.0 0.1 7.2 5.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.6 GAM39522.1 - 0.05 14.1 0.8 14 6.2 0.0 3.3 3 0 0 3 3 2 0 AAA domain DUF2075 PF09848.9 GAM39522.1 - 0.064 12.5 0.3 2.9 7.0 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 GAM39522.1 - 0.065 13.0 0.0 15 5.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 GAM39522.1 - 0.077 12.6 4.8 0.24 11.0 0.6 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 GAM39522.1 - 0.077 12.7 1.9 6.2 6.5 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein ATPase_2 PF01637.18 GAM39522.1 - 0.08 12.8 0.0 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 GAM39522.1 - 0.12 12.1 2.8 0.9 9.2 0.0 3.1 4 0 0 4 4 4 0 AAA domain AAA PF00004.29 GAM39522.1 - 0.12 12.8 0.9 16 6.0 0.0 3.3 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) DUF4400 PF14348.6 GAM39522.1 - 0.15 11.6 0.0 0.15 11.6 0.0 3.1 4 0 0 4 4 3 0 Domain of unknown function (DUF4400) Pox_A32 PF04665.12 GAM39522.1 - 0.27 10.7 1.7 6.8 6.1 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein NACHT PF05729.12 GAM39522.1 - 0.34 10.8 2.7 4.8 7.1 0.0 3.0 3 0 0 3 3 2 0 NACHT domain NTPase_1 PF03266.15 GAM39522.1 - 0.64 9.9 2.1 18 5.2 0.3 2.5 2 0 0 2 2 2 0 NTPase SGL PF08450.12 GAM39523.1 - 5.4e-27 94.9 0.0 1.3e-26 93.7 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF5050 PF16472.5 GAM39523.1 - 0.0075 15.5 0.0 0.018 14.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5050) PQQ_3 PF13570.6 GAM39523.1 - 0.37 11.4 5.2 0.62 10.6 0.3 3.2 3 1 0 3 3 3 0 PQQ-like domain Fungal_trans_2 PF11951.8 GAM39524.1 - 7.4e-13 48.1 0.0 1.5e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 GAM39525.1 - 4.1e-52 177.1 0.1 5.2e-52 176.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM39525.1 - 7.6e-47 159.3 0.3 9.9e-47 158.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM39525.1 - 1.2e-08 35.0 0.1 2e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM39525.1 - 0.0015 18.0 0.1 0.0047 16.4 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM39525.1 - 0.045 12.7 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans_2 PF11951.8 GAM39526.1 - 8e-05 21.6 0.3 0.1 11.4 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.16 GAM39527.1 - 1.1e-26 93.6 29.5 1.1e-26 93.6 29.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TraX PF05857.11 GAM39527.1 - 0.1 12.7 10.5 0.2 11.7 3.8 2.5 2 0 0 2 2 2 0 TraX protein Sugar_tr PF00083.24 GAM39528.1 - 4.2e-93 312.7 20.9 4.8e-93 312.5 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM39528.1 - 7.5e-26 90.9 25.6 9e-19 67.6 10.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Transketolase_N PF00456.21 GAM39529.1 - 4.1e-124 413.9 0.1 7.9e-124 413.0 0.0 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAM39529.1 - 2.9e-38 131.3 0.4 7e-38 130.1 0.1 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 GAM39529.1 - 6.5e-07 28.6 0.1 1.4e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.20 GAM39529.1 - 1.1e-05 25.3 0.0 5.7e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAM39529.1 - 3e-05 23.4 0.1 0.00017 20.9 0.1 2.2 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 GAM39529.1 - 0.00038 20.3 3.6 0.014 15.1 2.3 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NAD_binding_4 PF07993.12 GAM39530.1 - 5.9e-29 101.0 0.0 8.1e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 GAM39530.1 - 5.2e-09 35.9 0.0 8.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 GAM39530.1 - 0.00058 18.6 0.0 0.0011 17.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Semialdhyde_dh PF01118.24 GAM39530.1 - 0.0091 16.4 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain PP-binding PF00550.25 GAM39530.1 - 0.011 16.0 0.7 0.025 14.9 0.7 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site Isochorismatase PF00857.20 GAM39531.1 - 2.9e-23 83.0 0.0 3.5e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family EHN PF06441.12 GAM39532.1 - 2.2e-32 111.6 0.7 1.7e-31 108.8 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 GAM39532.1 - 2.7e-09 37.1 0.0 4.1e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF953 PF06110.11 GAM39533.1 - 1.7e-15 56.7 0.0 2.1e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 GAM39533.1 - 0.0067 16.2 0.0 0.0093 15.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Glyco_hydro_28 PF00295.17 GAM39534.1 - 1.6e-30 106.3 1.9 3.5e-30 105.2 1.9 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 GAM39534.1 - 1.9e-05 24.6 7.2 0.00056 19.8 2.6 3.2 1 1 1 2 2 2 2 Pectate lyase superfamily protein Sugar_tr PF00083.24 GAM39536.1 - 8.2e-61 206.2 20.8 9.5e-61 206.0 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM39536.1 - 4.5e-18 65.3 25.5 4.5e-18 65.3 25.5 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 GAM39536.1 - 0.00037 19.5 13.1 0.019 13.8 3.3 2.2 1 1 1 2 2 2 2 MFS_1 like family NrsF PF06532.11 GAM39536.1 - 0.0021 17.8 1.9 0.0021 17.8 1.9 2.1 2 1 1 3 3 3 1 Negative regulator of sigma F DUF1593 PF07632.11 GAM39537.1 - 5.9e-91 304.5 0.0 9.9e-91 303.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 GAM39537.1 - 8.8e-05 21.5 0.0 0.00013 20.9 0.0 1.2 1 0 0 1 1 1 1 REJ domain Speriolin_C PF15059.6 GAM39537.1 - 0.093 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Speriolin C-terminus HAD PF12710.7 GAM39538.1 - 1.4e-25 90.8 0.0 2.1e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 GAM39538.1 - 0.00021 20.8 0.0 0.00081 18.9 0.0 1.8 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 GAM39538.1 - 0.012 15.9 0.1 0.13 12.5 0.0 2.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 GAM39538.1 - 0.026 14.0 0.0 0.093 12.2 0.0 1.9 3 0 0 3 3 3 0 Pyrimidine 5'-nucleotidase (UMPH-1) MFS_1 PF07690.16 GAM39539.1 - 6.3e-44 150.3 29.2 6.3e-44 150.3 29.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM39539.1 - 9.3e-11 41.2 18.8 8.8e-10 38.0 19.3 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 GAM39539.1 - 6.8e-05 21.5 5.7 0.00012 20.7 5.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATP_transf PF09830.9 GAM39540.1 - 4.1e-12 46.1 0.0 6.2e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase adh_short_C2 PF13561.6 GAM39541.1 - 2.4e-60 204.0 0.5 2.7e-60 203.8 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM39541.1 - 7.2e-41 139.8 0.1 8.8e-41 139.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM39541.1 - 3.1e-10 40.3 0.7 4.9e-10 39.6 0.7 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 GAM39541.1 - 0.0012 18.7 0.1 0.0025 17.7 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 GAM39541.1 - 0.0026 18.4 0.0 0.0053 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 GAM39541.1 - 0.019 14.1 0.0 0.038 13.1 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAM39541.1 - 0.043 13.3 0.1 0.065 12.7 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 GAM39541.1 - 0.046 13.6 0.0 0.92 9.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain THF_DHG_CYH_C PF02882.19 GAM39541.1 - 0.049 12.9 0.1 0.14 11.5 0.1 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.19 GAM39541.1 - 0.1 11.6 0.1 0.28 10.2 0.1 1.7 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family RecC_C PF17946.1 GAM39541.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 RecC C-terminal domain NAD_binding_10 PF13460.6 GAM39541.1 - 0.19 11.6 2.3 0.69 9.8 0.6 2.3 2 1 0 2 2 2 0 NAD(P)H-binding Eno-Rase_NADH_b PF12242.8 GAM39541.1 - 0.26 11.1 1.3 4.5 7.1 0.3 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Myco_arth_vir_N PF09610.10 GAM39541.1 - 4.3 7.5 6.7 5.9 7.1 0.2 3.0 3 0 0 3 3 3 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Gln-synt_C PF00120.24 GAM39542.1 - 2e-82 277.0 0.0 2.4e-82 276.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Malate_synthase PF01274.22 GAM39543.1 - 1.4e-231 769.3 0.0 1.6e-231 769.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Sugar_tr PF00083.24 GAM39544.1 - 1.1e-68 232.2 24.6 1.4e-68 231.9 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM39544.1 - 6.4e-23 81.2 27.6 1.2e-17 63.9 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5592 PF17332.2 GAM39544.1 - 0.39 11.3 4.2 16 6.1 0.4 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5592) Fungal_trans PF04082.18 GAM39545.1 - 1.2e-07 31.1 2.7 1.9e-07 30.4 2.7 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_2_C PF02836.17 GAM39546.1 - 6.4e-109 363.7 0.0 9.1e-109 363.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 GAM39546.1 - 2.4e-66 223.8 0.0 4.2e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 GAM39546.1 - 3.2e-44 150.8 0.1 1.6e-43 148.6 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 GAM39546.1 - 6.8e-17 61.7 0.0 4.9e-16 59.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 GAM39546.1 - 3.7e-14 53.3 0.0 7e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_42 PF02449.15 GAM39546.1 - 0.0064 15.9 0.1 0.016 14.6 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydr_30_2 PF14587.6 GAM39547.1 - 1.1e-19 71.3 6.8 1.9e-19 70.5 6.8 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 GAM39547.1 - 1.9e-07 30.6 0.6 3.1e-07 29.9 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Meth_synt_2 PF01717.18 GAM39548.1 - 4.6e-13 49.1 0.0 2.7e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 GAM39548.1 - 0.089 12.3 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain Arf PF00025.21 GAM39549.1 - 5.8e-72 240.8 0.1 6.7e-72 240.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAM39549.1 - 3e-14 53.3 0.1 4e-14 52.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAM39549.1 - 7.8e-12 45.0 0.8 1.6e-07 30.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 GAM39549.1 - 1.6e-11 44.1 0.0 1.8e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 GAM39549.1 - 1.4e-10 40.9 0.0 1.7e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAM39549.1 - 8.8e-09 35.1 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM39549.1 - 0.00016 21.8 0.0 0.0012 18.9 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.18 GAM39549.1 - 0.0072 15.7 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Glycos_transf_1 PF00534.20 GAM39550.1 - 6.5e-21 74.6 0.0 1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAM39550.1 - 8e-12 45.7 0.0 1.4e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GAM39550.1 - 1.2e-05 25.6 0.0 2.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Hexapep PF00132.24 GAM39551.1 - 9.5e-07 28.3 13.9 0.0001 21.9 5.5 5.0 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAM39551.1 - 0.00033 20.3 0.8 0.00033 20.3 0.8 2.4 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 GAM39551.1 - 0.033 13.1 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase ABC2_membrane PF01061.24 GAM39552.1 - 1.7e-83 279.2 59.5 1e-42 145.9 20.7 3.4 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 GAM39552.1 - 2e-38 132.0 0.0 1e-17 64.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAM39552.1 - 2e-31 107.7 0.8 2e-31 107.7 0.8 3.9 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 GAM39552.1 - 2.2e-11 44.2 0.0 5.7e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 GAM39552.1 - 8.8e-07 29.5 0.1 0.0011 19.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 GAM39552.1 - 1.6e-05 24.6 0.2 0.00097 18.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAM39552.1 - 8e-05 22.8 0.1 0.15 12.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 GAM39552.1 - 0.00014 21.8 0.1 0.0063 16.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 GAM39552.1 - 0.00065 19.4 1.0 0.053 13.3 0.1 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_18 PF13238.6 GAM39552.1 - 0.00099 19.7 0.0 0.015 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 GAM39552.1 - 0.0035 16.5 23.5 0.0035 16.5 23.5 2.9 2 1 0 2 2 2 1 ABC-2 family transporter protein NACHT PF05729.12 GAM39552.1 - 0.011 15.6 1.3 1.9 8.3 0.2 2.9 3 0 0 3 3 3 0 NACHT domain AAA_17 PF13207.6 GAM39552.1 - 0.013 15.9 0.1 0.32 11.4 0.0 3.0 4 0 0 4 4 2 0 AAA domain MMR_HSR1 PF01926.23 GAM39552.1 - 0.014 15.5 0.0 5 7.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 GAM39552.1 - 0.018 14.6 0.8 0.11 12.1 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 GAM39552.1 - 0.021 15.1 0.1 1.7 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 GAM39552.1 - 0.03 14.1 0.3 1.5 8.5 0.1 2.5 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM39552.1 - 0.034 13.6 0.1 1.5 8.2 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain dNK PF01712.19 GAM39552.1 - 0.043 13.7 0.0 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_30 PF13604.6 GAM39552.1 - 0.054 13.2 0.2 0.54 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAM39552.1 - 0.056 13.8 0.1 18 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 GAM39552.1 - 0.16 12.4 0.1 11 6.5 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) FSA_C PF10479.9 GAM39554.1 - 7.3 4.6 17.5 9.2 4.3 17.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus MGC-24 PF05283.11 GAM39554.1 - 7.7 7.0 16.3 3 8.3 13.1 1.7 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Sugar_tr PF00083.24 GAM39555.1 - 1e-128 430.1 18.0 1.2e-128 429.9 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM39555.1 - 3.8e-19 68.8 34.7 4e-16 58.9 11.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 GAM39555.1 - 0.029 14.6 3.1 0.029 14.6 3.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) CcmF_C PF16327.5 GAM39556.1 - 0.02 14.2 2.0 0.035 13.4 2.0 1.3 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal Gate PF07670.14 GAM39556.1 - 0.034 14.4 0.2 0.085 13.1 0.2 1.6 1 0 0 1 1 1 0 Nucleoside recognition Insulin_TMD PF17870.1 GAM39556.1 - 0.041 13.9 2.0 0.089 12.9 0.1 2.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment PhoLip_ATPase_C PF16212.5 GAM39556.1 - 0.097 12.4 9.9 0.75 9.5 10.2 1.9 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal DUF3377 PF11857.8 GAM39556.1 - 0.22 11.4 0.0 0.22 11.4 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) SdpI PF13630.6 GAM39556.1 - 0.28 11.3 6.5 1.3 9.2 0.4 2.6 2 0 0 2 2 2 0 SdpI/YhfL protein family Ycf66_N PF07444.11 GAM39556.1 - 0.35 11.0 5.1 1.2 9.3 5.1 1.9 1 1 0 1 1 1 0 Ycf66 protein N-terminus Ferric_reduct PF01794.19 GAM39556.1 - 1.4 9.1 13.5 0.15 12.2 8.9 1.7 2 0 0 2 2 2 0 Ferric reductase like transmembrane component AMP-binding PF00501.28 GAM39557.1 - 3.7e-57 193.8 0.0 4.9e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM39557.1 - 1.6e-11 45.0 0.1 3.5e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4440 PF14534.6 GAM39558.1 - 4.1e-07 30.3 0.0 6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) FAD_binding_4 PF01565.23 GAM39560.1 - 3.1e-21 75.6 1.0 4.8e-21 75.0 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM39560.1 - 2e-05 24.6 0.0 4.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Epimerase PF01370.21 GAM39561.1 - 5.8e-19 68.5 0.0 8.6e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM39561.1 - 6.7e-16 58.1 0.0 8.8e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM39561.1 - 1.1e-09 38.2 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAM39561.1 - 5.9e-09 36.1 0.0 9.2e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 GAM39561.1 - 6.2e-09 35.4 0.1 7.3e-08 31.9 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 GAM39561.1 - 4.8e-06 26.6 0.0 7.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM39561.1 - 1e-05 24.8 0.1 0.00024 20.4 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 GAM39561.1 - 1.7e-05 24.3 0.1 0.00013 21.4 0.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase F420_oxidored PF03807.17 GAM39561.1 - 0.0009 19.8 0.0 0.002 18.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 GAM39561.1 - 0.0051 16.0 0.1 0.045 12.8 0.1 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 GAM39561.1 - 0.015 14.9 0.1 0.06 12.9 0.1 2.0 2 1 0 2 2 2 0 NmrA-like family Hira PF07569.11 GAM39561.1 - 0.039 13.7 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split Acetyltransf_10 PF13673.7 GAM39562.1 - 2e-08 34.2 0.0 3.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM39562.1 - 2.6e-07 30.9 0.0 3.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM39562.1 - 9.1e-06 26.0 0.0 1.4e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM39562.1 - 0.00056 20.0 0.1 0.0064 16.6 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM39562.1 - 0.0046 16.9 0.0 0.0097 15.9 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 GAM39562.1 - 0.038 14.1 0.0 0.088 13.0 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Methyltransf_24 PF13578.6 GAM39563.1 - 1.7e-09 38.6 0.1 9.2e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 GAM39563.1 - 3.3e-08 33.0 0.1 6.5e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 O-methyltransferase Flagellin_IN PF07196.13 GAM39565.1 - 0.06 13.5 0.2 0.11 12.7 0.2 1.3 1 0 0 1 1 1 0 Flagellin hook IN motif p47_phox_C PF08944.11 GAM39565.1 - 0.17 11.3 0.4 0.34 10.4 0.4 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain NAD_binding_4 PF07993.12 GAM39566.1 - 2.2e-71 240.1 0.0 3.2e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAM39566.1 - 7.4e-66 222.5 0.0 2.8e-65 220.6 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.25 GAM39566.1 - 1.5e-10 41.2 0.0 3.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 GAM39566.1 - 8.4e-08 31.5 0.0 1.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM39566.1 - 5.7e-07 29.2 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 GAM39566.1 - 1.8e-06 28.8 0.0 1.6e-05 25.8 0.0 2.7 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain KR PF08659.10 GAM39566.1 - 0.015 15.2 0.2 0.054 13.4 0.1 2.1 2 1 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 GAM39566.1 - 0.095 11.8 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAM39566.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.6 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Peptidase_M20 PF01546.28 GAM39567.1 - 2.3e-12 47.1 0.1 3.2e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM39567.1 - 7.7e-07 29.0 0.0 3.8e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain Phage_fiber PF03335.13 GAM39567.1 - 0.45 10.8 3.5 1.3 9.3 3.5 1.9 1 0 0 1 1 1 0 Phage tail fibre repeat Aldo_ket_red PF00248.21 GAM39569.1 - 1.2e-64 218.4 0.0 1.4e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RNase_T PF00929.24 GAM39570.1 - 2.8e-10 41.0 0.0 1e-09 39.1 0.0 2.0 2 0 0 2 2 2 1 Exonuclease zf-C2H2_4 PF13894.6 GAM39570.1 - 1.2e-07 31.9 3.9 0.0047 17.7 0.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM39570.1 - 2.1e-07 31.0 1.9 0.018 15.5 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 GAM39570.1 - 3.8e-07 30.2 0.8 0.034 14.4 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAM39570.1 - 7.1e-05 23.1 6.0 0.11 13.0 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 GAM39570.1 - 0.00034 20.5 7.0 0.0038 17.2 3.9 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 GAM39570.1 - 0.00051 19.9 0.9 0.034 14.1 0.1 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 GAM39570.1 - 0.011 15.5 1.4 0.011 15.5 1.4 1.7 2 0 0 2 2 2 0 zinc-finger C2H2-type DNA_pol_A_exo1 PF01612.20 GAM39570.1 - 0.014 15.1 0.0 0.079 12.7 0.0 2.1 2 0 0 2 2 2 0 3'-5' exonuclease zf-Di19 PF05605.12 GAM39570.1 - 0.2 12.0 4.0 0.48 10.8 4.0 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 GAM39570.1 - 0.21 11.9 4.7 4.3 7.7 0.7 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Prok-RING_4 PF14447.6 GAM39570.1 - 0.45 10.4 3.1 2.9 7.8 3.3 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-H2C2_2 PF13465.6 GAM39570.1 - 1 9.9 7.1 8.1 7.1 2.9 2.8 2 0 0 2 2 2 0 Zinc-finger double domain E_Pc_C PF06752.12 GAM39571.1 - 4.4 7.3 16.0 0.61 10.1 12.1 1.5 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus Transp_cyt_pur PF02133.15 GAM39572.1 - 1.6e-95 320.5 31.4 1.9e-95 320.2 31.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.6 GAM39573.1 - 3.1e-24 86.0 0.0 5e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM39573.1 - 4.3e-20 72.1 0.0 9.5e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 GAM39574.1 - 3.5e-23 82.0 0.2 6.7e-23 81.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM39574.1 - 6.8e-05 22.9 7.0 0.00011 22.2 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 GAM39575.1 - 9.8e-86 288.5 0.1 1.2e-85 288.2 0.1 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.20 GAM39575.1 - 2.1e-38 132.3 0.0 4.1e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family Abhydrolase_6 PF12697.7 GAM39577.1 - 6.2e-08 33.5 0.2 9.4e-08 32.9 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM39577.1 - 1.5e-05 24.4 0.1 2.6e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAM39577.1 - 0.00079 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Phlebovirus_NSM PF07246.11 GAM39579.1 - 0.33 10.3 3.1 0.44 9.9 3.1 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M PQ-loop PF04193.14 GAM39580.1 - 2e-22 78.7 21.6 3.8e-12 45.8 2.8 3.7 3 1 1 4 4 4 2 PQ loop repeat TMEM107 PF14995.6 GAM39580.1 - 0.00042 20.7 2.5 0.00088 19.7 2.3 1.7 1 1 0 1 1 1 1 Transmembrane protein ER_lumen_recept PF00810.18 GAM39580.1 - 0.43 11.4 6.9 0.07 13.9 2.3 2.0 2 1 0 2 2 2 0 ER lumen protein retaining receptor Ish1 PF10281.9 GAM39581.1 - 1.3e-87 287.8 23.2 2e-14 53.6 0.1 7.5 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.7 GAM39581.1 - 2.1e-09 36.9 0.1 0.52 10.1 0.0 5.8 6 0 0 6 6 6 3 HeH/LEM domain SAP PF02037.27 GAM39581.1 - 1.4e-07 31.1 0.0 4.5 7.1 0.0 6.2 6 0 0 6 6 6 2 SAP domain Slx4 PF09494.10 GAM39581.1 - 1.2e-06 28.4 0.2 8 6.5 0.0 5.8 6 0 0 6 6 6 1 Slx4 endonuclease DUF4224 PF13986.6 GAM39581.1 - 0.035 14.0 0.0 19 5.2 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4224) DUF3879 PF12995.7 GAM39581.1 - 0.042 13.6 0.7 1.4 8.6 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3879) Thymopoietin PF08198.11 GAM39581.1 - 0.1 12.2 0.2 66 3.2 0.0 3.7 4 0 0 4 4 4 0 Thymopoietin protein Caudo_TAP PF02413.17 GAM39581.1 - 0.18 11.9 8.6 2.3 8.4 0.5 3.6 3 1 0 3 3 3 0 Caudovirales tail fibre assembly protein, lambda gpK SAM_2 PF07647.17 GAM39581.1 - 0.59 10.3 6.7 88 3.3 0.2 5.2 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) 6PGD PF00393.19 GAM39581.1 - 0.62 9.4 11.2 3.6 6.9 0.4 4.8 2 2 4 6 6 6 0 6-phosphogluconate dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 GAM39583.1 - 1.4e-14 54.0 0.0 1.9e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4519 PF15012.6 GAM39583.1 - 0.018 15.2 0.2 0.029 14.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DHR10 PF18595.1 GAM39584.1 - 5.1e-05 23.3 3.9 0.00011 22.2 3.9 1.5 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain Seryl_tRNA_N PF02403.22 GAM39584.1 - 9.3 6.5 7.0 1 9.7 1.8 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMA7 PF09072.10 GAM39585.1 - 8.1e-27 93.8 22.4 9e-27 93.7 22.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.25 GAM39586.1 - 8.4e-54 182.7 0.0 1.3e-53 182.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM39586.1 - 6e-25 88.0 0.0 2.4e-24 86.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 GAM39586.1 - 0.037 13.0 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase LRIF1 PF15741.5 GAM39586.1 - 0.083 11.4 5.1 0.14 10.7 5.1 1.3 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Pkinase_fungal PF17667.1 GAM39586.1 - 0.14 10.9 0.0 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Acyl-CoA_dh_M PF02770.19 GAM39587.1 - 0.00033 20.8 0.0 0.0007 19.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain p450 PF00067.22 GAM39588.1 - 7.8e-52 176.5 0.0 1.1e-51 176.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2309 PF10070.9 GAM39588.1 - 0.24 9.7 0.0 0.35 9.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Pkinase PF00069.25 GAM39589.1 - 7.9e-50 169.7 0.0 1e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM39589.1 - 3.4e-30 105.2 0.0 4.1e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM39589.1 - 0.0041 17.1 0.0 0.0091 15.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAM39589.1 - 0.024 14.0 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAM39589.1 - 0.18 10.7 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 GAM39589.1 - 0.21 11.2 0.0 1.1 8.9 0.0 1.8 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 adh_short_C2 PF13561.6 GAM39590.1 - 4.9e-37 127.7 8.5 5.9e-27 94.7 8.7 3.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM39590.1 - 1.3e-35 122.7 5.3 4.3e-35 120.9 5.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM39590.1 - 1.3e-09 38.3 2.3 6.4e-09 36.0 2.3 1.9 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 GAM39590.1 - 0.0041 17.0 0.6 0.0064 16.4 0.6 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAM39590.1 - 0.015 14.7 0.1 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 GAM39590.1 - 0.02 14.1 0.1 0.027 13.6 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 GAM39590.1 - 0.034 14.2 0.1 0.059 13.4 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 GAM39590.1 - 0.047 13.3 0.3 0.069 12.7 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4979 PF16351.5 GAM39591.1 - 0.22 11.8 3.8 0.33 11.2 2.7 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4979) ADH_N PF08240.12 GAM39592.1 - 3.4e-22 78.4 1.4 5.1e-22 77.8 0.8 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM39592.1 - 1.7e-13 50.6 0.0 4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAM39592.1 - 6.9e-06 25.5 0.1 1.1e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAM39592.1 - 0.00012 21.5 0.2 0.00034 20.0 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.18 GAM39593.1 - 4.6e-24 84.9 1.7 7.1e-24 84.3 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM39593.1 - 1.8e-08 34.4 13.6 3.1e-08 33.6 13.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4094 PF13334.6 GAM39593.1 - 0.086 13.3 0.3 0.086 13.3 0.3 2.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4094) Cep57_CLD_2 PF14197.6 GAM39593.1 - 0.087 12.9 1.2 0.19 11.8 1.2 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Dynamitin PF04912.14 GAM39593.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Dynamitin PRKG1_interact PF15898.5 GAM39593.1 - 0.12 13.3 0.2 0.25 12.2 0.2 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Filament PF00038.21 GAM39593.1 - 0.17 11.5 0.5 0.26 10.8 0.5 1.2 1 0 0 1 1 1 0 Intermediate filament protein CCDC-167 PF15188.6 GAM39593.1 - 0.18 12.1 0.3 0.37 11.2 0.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 MutS_IV PF05190.18 GAM39593.1 - 0.18 12.1 0.0 0.5 10.7 0.0 1.7 1 0 0 1 1 1 0 MutS family domain IV Csm1_N PF18504.1 GAM39593.1 - 0.21 11.9 1.3 0.49 10.8 1.3 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain Myc-LZ PF02344.15 GAM39593.1 - 4.1 7.6 8.4 11 6.2 8.4 1.7 1 0 0 1 1 1 0 Myc leucine zipper domain HlyIII PF03006.20 GAM39595.1 - 9.4e-65 218.5 12.0 1.1e-64 218.2 12.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related 60KD_IMP PF02096.20 GAM39595.1 - 0.15 11.9 1.1 0.27 11.1 1.1 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein TssN PF17555.2 GAM39595.1 - 1.4 8.2 4.1 0.64 9.4 0.5 2.0 1 1 1 2 2 2 0 Type VI secretion system, TssN CSN8_PSD8_EIF3K PF10075.9 GAM39596.1 - 0.052 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family TPR_19 PF14559.6 GAM39597.1 - 3.8e-06 27.3 1.9 0.031 14.8 0.0 3.2 3 1 1 4 4 4 3 Tetratricopeptide repeat Glycos_transf_2 PF00535.26 GAM39598.1 - 1.3e-34 119.5 0.0 1.5e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAM39598.1 - 1.8e-13 50.9 0.0 2.2e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GAM39598.1 - 2.6e-06 27.1 0.0 3.5e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GAM39598.1 - 0.00069 19.1 0.0 0.0012 18.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 GAM39598.1 - 0.0055 16.7 0.0 0.0075 16.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DUF1749 PF08538.10 GAM39599.1 - 5.1e-101 337.7 0.0 6.2e-101 337.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 GAM39599.1 - 0.0016 19.1 0.0 0.0024 18.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM39599.1 - 0.003 16.8 0.4 0.034 13.4 0.0 2.6 3 0 0 3 3 3 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAM39599.1 - 0.082 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 GAM39599.1 - 0.098 12.2 0.1 0.78 9.2 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 GAM39599.1 - 0.11 12.0 0.1 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Glyco_hydro_47 PF01532.20 GAM39600.1 - 3.5e-167 556.9 0.0 3.2e-165 550.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 GAM39600.1 - 0.087 12.3 1.1 14 5.1 0.4 2.5 2 1 0 2 2 2 0 Glycosyl hydrolase family 76 Ge1_WD40 PF16529.5 GAM39603.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Vps35 PF03635.17 GAM39604.1 - 0 1031.9 3.6 0 1031.7 3.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Spore_coat_CotO PF14153.6 GAM39604.1 - 0.24 11.3 8.0 0.49 10.3 8.0 1.4 1 0 0 1 1 1 0 Spore coat protein CotO NST1 PF13945.6 GAM39605.1 - 8e-69 231.6 7.4 8e-69 231.6 7.4 5.6 3 2 2 5 5 5 1 Salt tolerance down-regulator Ras PF00071.22 GAM39606.1 - 1.7e-48 164.3 0.0 2e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM39606.1 - 6.3e-22 78.1 0.0 8.9e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM39606.1 - 9.1e-07 28.5 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM39606.1 - 0.012 15.0 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAM39606.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 GAM39606.1 - 0.071 12.9 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 GAM39606.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 GAM39606.1 - 0.22 11.3 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MRP-L28 PF09812.9 GAM39607.1 - 5.6e-06 26.6 1.6 7.3e-06 26.2 1.4 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L28 FANCL_C PF11793.8 GAM39608.1 - 2.4e-06 27.6 2.5 4.5e-06 26.7 2.5 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 GAM39608.1 - 5.5e-05 23.2 7.4 0.00011 22.3 7.4 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 GAM39608.1 - 0.097 13.0 6.5 0.19 12.1 6.5 1.5 1 0 0 1 1 1 0 Ring finger domain TPP_enzyme_N PF02776.18 GAM39609.1 - 9.1e-56 188.2 0.0 1.6e-54 184.1 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAM39609.1 - 1.8e-50 170.7 0.0 2.2e-49 167.2 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAM39609.1 - 8.1e-38 129.3 0.1 1.7e-37 128.2 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain GalKase_gal_bdg PF10509.9 GAM39610.1 - 8.5e-22 76.5 0.0 1.5e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 GAM39610.1 - 4.7e-15 55.6 4.0 6.5e-15 55.1 2.1 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain HTH_3 PF01381.22 GAM39610.1 - 0.0042 17.1 0.3 1.5 8.9 0.1 2.8 2 0 0 2 2 2 2 Helix-turn-helix DUF1073 PF06381.11 GAM39610.1 - 0.086 11.6 0.0 0.39 9.4 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1073) RNase_H2-Ydr279 PF09468.10 GAM39611.1 - 1.7e-42 145.3 2.5 4.1e-42 144.1 2.5 1.7 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 GAM39611.1 - 8e-22 77.3 0.4 3.9e-21 75.1 0.0 2.4 3 0 0 3 3 3 1 Ydr279p protein triple barrel domain RAI16-like PF10257.9 GAM39611.1 - 0.0068 15.3 0.1 0.01 14.7 0.1 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein zf-primase PF09329.11 GAM39612.1 - 6e-18 64.4 1.8 1e-17 63.6 1.8 1.4 1 0 0 1 1 1 1 Primase zinc finger DUF4410 PF14366.6 GAM39612.1 - 0.062 13.2 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) HpcH_HpaI PF03328.14 GAM39613.1 - 4.6e-33 114.2 0.0 6.1e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family RTA1 PF04479.13 GAM39614.1 - 1e-62 211.4 14.0 1e-62 211.4 14.0 1.6 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.8 GAM39615.1 - 0.00019 20.4 0.9 0.00019 20.4 0.9 1.8 1 1 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.13 GAM39616.1 - 1.8e-68 230.2 11.1 1.8e-68 230.2 11.1 1.8 1 1 1 2 2 2 1 RTA1 like protein NACHT_N PF17100.5 GAM39617.1 - 9e-62 208.8 0.0 9e-62 208.8 0.0 2.1 3 0 0 3 3 3 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 GAM39617.1 - 2.2e-46 156.3 7.4 8.7e-18 64.7 0.2 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM39617.1 - 2.9e-36 119.3 2.2 0.0012 19.2 0.0 8.6 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 GAM39617.1 - 1.2e-35 121.4 1.6 7.6e-09 36.0 0.0 5.8 2 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 GAM39617.1 - 3.3e-32 109.5 6.5 7.8e-05 22.9 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 GAM39617.1 - 1.7e-24 85.6 8.1 9.4e-08 32.2 0.1 5.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) AAA_16 PF13191.6 GAM39617.1 - 7.7e-05 23.1 0.0 0.00052 20.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 GAM39617.1 - 8.1e-05 22.6 0.0 0.00023 21.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GAM39617.1 - 0.00018 21.8 0.0 0.00093 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain VWA_3_C PF18571.1 GAM39617.1 - 0.00084 19.2 6.3 16 5.5 0.1 6.1 7 0 0 7 7 7 0 von Willebrand factor type A C-terminal domain AAA PF00004.29 GAM39617.1 - 0.0063 16.9 0.0 0.021 15.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cohesin_HEAT PF12765.7 GAM39617.1 - 0.013 15.8 0.1 0.033 14.5 0.1 1.8 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion DASH_Duo1 PF08651.10 GAM39619.1 - 1.5e-30 104.7 2.7 2.9e-30 103.9 1.3 2.1 2 0 0 2 2 2 1 DASH complex subunit Duo1 Taxilin PF09728.9 GAM39619.1 - 0.12 11.6 10.8 0.19 10.9 10.8 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF745 PF05335.13 GAM39619.1 - 0.13 12.0 15.6 0.22 11.3 15.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF1682 PF07946.14 GAM39619.1 - 2.9 7.0 8.0 4.2 6.5 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FCH PF00611.23 GAM39620.1 - 3.3e-16 59.3 0.4 1.3e-15 57.4 0.0 2.3 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 GAM39620.1 - 3.1e-13 49.1 0.0 6.9e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAM39620.1 - 1.7e-11 43.6 0.0 7.1e-11 41.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 GAM39620.1 - 1.5e-10 40.8 0.0 3.7e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Rapsyn_N PF10579.9 GAM39620.1 - 0.16 12.1 0.8 0.38 10.9 0.7 1.7 1 1 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region Aldo_ket_red PF00248.21 GAM39621.1 - 5.6e-29 101.3 0.0 2.9e-28 98.9 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Not1 PF04054.15 GAM39622.1 - 3.6e-141 470.4 0.3 8.8e-141 469.1 0.1 1.8 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 GAM39622.1 - 3.7e-97 324.1 2.2 8.1e-97 323.0 2.2 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 GAM39622.1 - 7.1e-52 175.2 3.8 1.4e-51 174.3 3.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 GAM39622.1 - 2e-41 141.3 0.0 8.3e-41 139.2 0.0 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 GAM39622.1 - 3.4e-29 101.9 0.2 3.4e-29 101.9 0.2 2.4 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Seipin PF06775.14 GAM39623.1 - 9e-64 215.2 0.5 1.1e-63 214.9 0.5 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) TTL PF03133.15 GAM39624.1 - 4.7e-57 193.3 0.0 7e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 GAM39624.1 - 3.4e-49 167.3 0.1 4.8e-49 166.8 0.1 1.2 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 GAM39624.1 - 0.0014 17.9 0.0 0.0042 16.4 0.0 1.7 2 0 0 2 2 2 1 YheC/D like ATP-grasp Glyco_trans_4_2 PF13477.6 GAM39624.1 - 0.045 13.8 0.3 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like Glyco_trans_4_4 PF13579.6 GAM39624.1 - 0.098 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain ABC_tran PF00005.27 GAM39625.1 - 8.5e-34 117.0 0.0 1.6e-33 116.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GAM39625.1 - 1.2e-20 74.3 3.2 2.1e-20 73.5 3.2 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 GAM39625.1 - 8.9e-06 25.3 0.0 0.00046 19.7 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAM39625.1 - 0.0015 18.8 0.0 0.0049 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM39625.1 - 0.0032 17.9 0.1 0.0072 16.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 GAM39625.1 - 0.0033 17.5 0.0 0.0077 16.4 0.0 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain DUF815 PF05673.13 GAM39625.1 - 0.015 14.5 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 GAM39625.1 - 0.017 14.9 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM39625.1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase G-alpha PF00503.20 GAM39625.1 - 0.044 13.0 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DEAD PF00270.29 GAM39625.1 - 0.048 13.4 0.1 0.15 11.9 0.1 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_30 PF13604.6 GAM39625.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM39625.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 GAM39625.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain CECR6_TMEM121 PF14997.6 GAM39625.1 - 1.1 9.0 4.9 9.7 6.0 0.4 3.2 3 0 0 3 3 3 0 CECR6/TMEM121 family Pex14_N PF04695.13 GAM39627.1 - 2.6e-41 141.9 0.1 2.6e-41 141.9 0.1 2.7 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Golgin_A5 PF09787.9 GAM39627.1 - 0.0029 17.1 0.9 0.0045 16.5 0.9 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 GAM39627.1 - 0.0062 16.6 0.8 2 8.5 0.3 2.1 1 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_tail_1 PF01576.19 GAM39627.1 - 0.028 12.3 9.5 0.032 12.0 7.6 1.7 1 1 1 2 2 2 0 Myosin tail DUF1043 PF06295.12 GAM39627.1 - 0.04 13.9 1.6 0.045 13.7 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF3584 PF12128.8 GAM39627.1 - 0.085 10.4 6.1 0.12 9.9 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TRADD_N PF09034.10 GAM39627.1 - 0.15 12.1 1.0 0.27 11.3 1.0 1.3 1 0 0 1 1 1 0 TRADD, N-terminal domain FUSC PF04632.12 GAM39627.1 - 0.25 9.8 1.5 0.35 9.4 1.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 GAM39627.1 - 0.43 10.6 2.3 1.2 9.2 2.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 GAM39627.1 - 0.47 9.7 3.3 0.89 8.8 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C4H2 PF10146.9 GAM39627.1 - 1 9.6 9.4 0.045 14.1 1.8 2.3 2 1 0 2 2 2 0 Zinc finger-containing protein Ndc80_HEC PF03801.13 GAM39628.1 - 2.3e-61 205.9 0.1 7.4e-61 204.3 0.1 1.9 1 0 0 1 1 1 1 HEC/Ndc80p family PPR PF01535.20 GAM39628.1 - 0.011 15.9 0.0 0.038 14.2 0.0 2.0 1 0 0 1 1 1 0 PPR repeat DUF16 PF01519.16 GAM39628.1 - 0.014 15.9 5.2 0.014 15.9 5.2 4.2 5 0 0 5 5 5 0 Protein of unknown function DUF16 Filament PF00038.21 GAM39628.1 - 0.17 11.4 48.7 0.086 12.4 21.9 3.3 2 1 0 2 2 2 0 Intermediate filament protein WD40_alt PF14077.6 GAM39628.1 - 0.39 10.6 2.1 1.3 8.9 0.1 2.7 2 0 0 2 2 2 0 Alternative WD40 repeat motif TPR_MLP1_2 PF07926.12 GAM39628.1 - 0.67 10.0 49.7 0.025 14.7 11.0 4.5 4 1 1 5 5 5 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 GAM39628.1 - 4.2 6.2 49.5 0.079 11.8 15.4 3.4 2 2 2 4 4 4 0 Spc7 kinetochore protein Lebercilin PF15619.6 GAM39628.1 - 8.6 6.0 47.0 6.7 6.3 22.3 3.2 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fungal_trans PF04082.18 GAM39629.1 - 1.1e-20 73.8 0.9 2e-20 72.9 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM39629.1 - 2.7e-07 30.6 12.0 2.7e-07 30.6 12.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.15 GAM39629.1 - 0.14 12.3 1.0 0.54 10.4 1.0 2.0 1 0 0 1 1 1 0 Basic region leucine zipper PIF PF05092.12 GAM39629.1 - 0.99 8.0 3.0 1.6 7.3 3.0 1.2 1 0 0 1 1 1 0 Per os infectivity Pkinase PF00069.25 GAM39630.1 - 1.4e-67 227.8 0.0 1.9e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM39630.1 - 4.7e-30 104.7 0.0 6.7e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAM39630.1 - 0.017 14.1 0.1 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 GAM39630.1 - 0.032 13.6 0.0 0.15 11.3 0.0 2.0 1 1 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 GAM39630.1 - 0.037 12.8 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 GAM39630.1 - 0.15 11.7 0.1 5.5 6.5 0.0 2.6 1 1 2 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 FolB PF02152.18 GAM39631.1 - 2.8e-24 85.8 0.5 6.4e-21 75.0 0.1 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase MatE PF01554.18 GAM39632.1 - 6.5e-53 178.7 20.1 5.6e-29 100.9 3.7 3.2 2 1 1 3 3 3 3 MatE CD225 PF04505.12 GAM39632.1 - 0.3 11.3 3.4 0.17 12.0 0.4 2.3 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Arginase PF00491.21 GAM39633.1 - 4e-90 302.1 0.0 5.1e-90 301.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 GAM39633.1 - 0.069 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain MARVEL PF01284.23 GAM39633.1 - 0.07 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Membrane-associating domain AA_permease_2 PF13520.6 GAM39634.1 - 1.9e-44 152.2 49.6 2.4e-44 151.9 49.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM39634.1 - 4.7e-26 91.4 42.0 7.3e-26 90.8 42.0 1.2 1 0 0 1 1 1 1 Amino acid permease DUF962 PF06127.11 GAM39634.1 - 1.5 9.0 7.6 2.7 8.2 5.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF962) SID-1_RNA_chan PF13965.6 GAM39634.1 - 5.5 5.3 9.0 4.7 5.5 5.6 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 ETF_QO PF05187.13 GAM39635.1 - 1.4e-46 156.9 0.2 2.6e-46 156.0 0.2 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S RRM_1 PF00076.22 GAM39635.1 - 1.9e-21 75.6 0.0 3.1e-10 39.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DAO PF01266.24 GAM39635.1 - 2.7e-07 30.5 0.0 0.00038 20.1 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM39635.1 - 3.6e-06 27.1 0.0 9e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM39635.1 - 0.00011 21.4 0.3 0.026 13.6 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAM39635.1 - 0.00017 21.0 0.0 0.00049 19.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM39635.1 - 0.002 18.7 0.1 1.1 9.9 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM39635.1 - 0.0025 16.6 0.5 0.0041 15.9 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 GAM39635.1 - 0.0039 16.5 0.0 0.028 13.7 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 GAM39635.1 - 0.0043 16.3 0.2 0.0076 15.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 GAM39635.1 - 0.0062 16.5 0.1 0.018 15.0 0.1 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 GAM39635.1 - 0.0069 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAM39635.1 - 0.015 14.6 0.5 0.022 14.0 0.5 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM39635.1 - 0.034 13.0 0.0 0.41 9.4 0.2 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Fer4_7 PF12838.7 GAM39635.1 - 0.046 14.3 0.7 0.13 12.9 0.7 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 GAM39635.1 - 0.14 11.1 0.3 0.22 10.6 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TBP PF00352.21 GAM39636.1 - 1.2e-67 223.8 0.1 9.2e-33 112.1 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 GAM39636.1 - 5.9e-05 23.1 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 GAM39636.1 - 0.13 12.1 0.1 0.68 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) DAO PF01266.24 GAM39637.1 - 1.6e-42 146.3 0.0 1.9e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM39637.1 - 7.5e-08 31.9 0.1 1.2e-05 24.8 0.2 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 GAM39637.1 - 1.6e-06 27.7 0.1 0.026 13.9 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.24 GAM39637.1 - 5.7e-05 22.4 0.1 0.019 14.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 GAM39637.1 - 0.0011 19.0 0.2 0.67 9.9 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAM39637.1 - 0.0047 17.1 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAM39637.1 - 0.0048 16.0 0.1 0.038 13.1 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GAM39637.1 - 0.0074 15.4 0.1 0.019 14.1 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 GAM39637.1 - 0.02 14.2 0.3 0.093 12.0 0.0 2.1 3 0 0 3 3 3 0 Thi4 family FAD_binding_3 PF01494.19 GAM39637.1 - 0.028 13.7 0.0 3.5 6.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 GAM39637.1 - 0.033 14.4 0.0 0.083 13.1 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.27 GAM39637.1 - 0.039 14.5 0.0 0.12 12.9 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM39637.1 - 0.076 11.9 0.4 0.43 9.4 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 GAM39637.1 - 0.13 11.3 0.0 13 4.8 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Methyltransf_23 PF13489.6 GAM39638.1 - 1.7e-38 132.1 0.0 2.3e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM39638.1 - 2.2e-07 31.5 0.0 9.5e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM39638.1 - 8.6e-07 29.6 0.0 1.6e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM39638.1 - 1.3e-05 25.7 0.0 6e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM39638.1 - 0.00018 21.4 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM39638.1 - 0.057 12.7 0.0 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Cyclin_N PF00134.23 GAM39640.1 - 1.6e-14 53.7 0.1 3.3e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 GAM39640.1 - 0.011 15.8 0.4 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Cyclin_C PF02984.19 GAM39640.1 - 0.012 15.7 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain EAF PF09816.9 GAM39641.1 - 1e-20 74.0 1.4 1.7e-20 73.3 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Big_3_2 PF12245.8 GAM39641.1 - 0.0035 17.6 0.4 0.0069 16.7 0.4 1.4 1 0 0 1 1 1 1 Bacterial Ig-like domain Big_3_3 PF13750.6 GAM39641.1 - 0.011 15.3 0.1 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) BTV_NS2 PF04514.12 GAM39641.1 - 0.028 13.3 0.3 0.072 11.9 0.3 1.6 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Dor1 PF04124.12 GAM39642.1 - 4.1e-51 173.7 2.5 1.6e-41 142.1 1.6 2.8 2 1 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 GAM39642.1 - 0.001 19.1 0.8 0.0036 17.4 0.8 2.0 1 0 0 1 1 1 1 Vps51/Vps67 His_Phos_1 PF00300.22 GAM39643.1 - 3.1e-28 98.8 0.2 8.9e-28 97.3 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 GAM39643.1 - 0.011 15.1 0.9 0.018 14.4 0.0 1.7 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) P5-ATPase PF12409.8 GAM39643.1 - 0.021 14.9 2.1 0.081 13.0 0.0 2.3 2 0 0 2 2 2 0 P5-type ATPase cation transporter Spem1 PF15670.5 GAM39643.1 - 2.9 7.4 6.5 1.6 8.3 3.6 1.9 2 0 0 2 2 2 0 Spermatid maturation protein 1 Cyclin PF08613.11 GAM39644.1 - 2.4e-11 44.3 0.0 4.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAM39644.1 - 4.1e-05 23.3 0.0 7.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF2380 PF09533.10 GAM39644.1 - 0.036 13.7 1.9 0.038 13.6 0.2 1.9 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) RSF PF14876.6 GAM39644.1 - 0.077 12.0 0.4 0.12 11.3 0.4 1.2 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator CRC_subunit PF08624.10 GAM39645.1 - 7.5e-51 172.1 0.1 1.4e-50 171.2 0.1 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Pkinase PF00069.25 GAM39646.1 - 4.1e-69 232.9 0.0 5.6e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM39646.1 - 2.5e-31 108.9 0.0 3.5e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAM39646.1 - 6.8e-14 52.3 0.6 5.1e-13 49.5 0.6 2.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 GAM39646.1 - 5e-09 35.9 0.1 2.3e-08 33.7 0.0 1.9 1 1 1 2 2 2 1 Kinase-like C2 PF00168.30 GAM39646.1 - 7.4e-09 35.8 0.0 3e-06 27.5 0.0 2.6 2 0 0 2 2 2 1 C2 domain Haspin_kinase PF12330.8 GAM39646.1 - 0.00011 21.3 0.2 0.00028 19.9 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAM39646.1 - 0.0026 17.7 0.1 0.0088 16.0 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 GAM39646.1 - 0.018 14.7 0.4 1.7 8.2 0.1 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 GAM39646.1 - 0.057 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Adeno_E3_15_3 PF03307.14 GAM39646.1 - 0.061 13.3 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region Kdo PF06293.14 GAM39646.1 - 0.088 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 GAM39647.1 - 0.17 11.8 1.5 0.36 10.8 0.1 2.3 3 0 0 3 3 3 0 F-box-like LRR_8 PF13855.6 GAM39647.1 - 2 8.2 4.8 0.71 9.7 1.0 2.3 2 0 0 2 2 2 0 Leucine rich repeat SPX PF03105.19 GAM39647.1 - 6.7 6.5 13.2 1.2 9.0 6.4 2.3 2 0 0 2 2 2 0 SPX domain AAA PF00004.29 GAM39648.1 - 7.6e-41 139.6 0.2 2.3e-40 138.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAM39648.1 - 1e-18 67.0 0.2 2e-18 66.1 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAM39648.1 - 9.7e-10 38.1 0.0 2.1e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAM39648.1 - 2.5e-05 24.3 0.0 0.00012 22.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM39648.1 - 0.00016 22.1 1.5 0.019 15.4 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 GAM39648.1 - 0.00026 20.8 0.0 0.00061 19.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAM39648.1 - 0.001 19.2 1.2 0.0097 16.0 0.0 2.9 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAM39648.1 - 0.0022 18.3 2.0 0.1 12.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain PhoH PF02562.16 GAM39648.1 - 0.0041 16.6 0.2 0.06 12.8 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 GAM39648.1 - 0.008 15.6 0.1 0.024 14.0 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAM39648.1 - 0.0095 16.1 0.1 0.038 14.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAM39648.1 - 0.019 14.2 0.0 0.048 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 GAM39648.1 - 0.062 13.0 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 GAM39648.1 - 0.1 12.3 0.5 0.38 10.5 0.1 2.2 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.6 GAM39648.1 - 0.25 11.1 6.5 0.28 10.9 0.0 2.8 2 1 0 3 3 3 0 AAA domain CLZ PF16526.5 GAM39648.1 - 0.69 10.3 10.9 0.15 12.4 6.3 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Atg14 PF10186.9 GAM39648.1 - 1.2 8.1 3.2 2.3 7.2 3.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RRN3 PF05327.11 GAM39648.1 - 2 6.8 10.9 2.9 6.3 10.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BLOC1_2 PF10046.9 GAM39648.1 - 3.6 8.0 6.5 1.3 9.4 0.9 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TauD PF02668.16 GAM39649.1 - 3.4e-36 125.4 1.0 5e-36 124.9 1.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 GAM39649.1 - 0.042 13.0 0.0 0.39 9.8 0.0 2.0 2 0 0 2 2 2 0 CsiD BrkDBD PF09607.10 GAM39649.1 - 0.049 13.4 0.5 0.13 12.1 0.5 1.6 1 0 0 1 1 1 0 Brinker DNA-binding domain MaoC_dehydratas PF01575.19 GAM39650.1 - 7.6e-22 77.2 0.0 1.6e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 GAM39650.1 - 7.6e-05 22.9 0.0 0.5 10.5 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase COesterase PF00135.28 GAM39651.1 - 1.2e-95 321.3 0.0 1.5e-95 321.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM39651.1 - 7.7e-06 25.9 0.5 0.0014 18.5 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM39651.1 - 0.047 13.2 0.2 0.087 12.3 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Methyltransf_25 PF13649.6 GAM39652.1 - 7e-13 49.1 0.0 1.4e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAM39652.1 - 4.5e-11 42.7 0.0 7.4e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 GAM39652.1 - 2.9e-10 40.1 0.0 4.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM39652.1 - 2.6e-09 37.6 0.0 5.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM39652.1 - 2.9e-06 27.2 0.0 5.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 GAM39652.1 - 3.9e-06 26.0 0.1 5.8e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 GAM39652.1 - 1.4e-05 24.5 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 GAM39652.1 - 2.4e-05 24.3 0.5 0.00017 21.6 0.1 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM39652.1 - 0.00025 21.7 0.0 0.00048 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM39652.1 - 0.00048 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 GAM39652.1 - 0.0017 17.7 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 GAM39652.1 - 0.0032 17.6 0.0 0.0056 16.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PRMT5 PF05185.16 GAM39652.1 - 0.0047 16.8 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 GAM39652.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 GAM39652.1 - 0.016 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase TehB PF03848.14 GAM39652.1 - 0.043 13.2 0.1 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB PCMT PF01135.19 GAM39652.1 - 0.05 13.4 0.1 0.083 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 GAM39652.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Per1 PF04080.13 GAM39653.1 - 3.1e-103 345.0 16.7 3.9e-103 344.7 16.7 1.1 1 0 0 1 1 1 1 Per1-like family Syndecan PF01034.20 GAM39653.1 - 0.14 12.1 0.7 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 Syndecan domain PGM_PMM_I PF02878.16 GAM39654.1 - 1.6e-15 57.0 0.3 3e-07 30.2 0.0 3.1 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 GAM39654.1 - 1.2e-12 47.8 1.8 6.7e-12 45.4 1.1 2.6 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 GAM39654.1 - 0.001 19.2 0.8 0.006 16.8 0.8 2.2 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 GAM39654.1 - 0.0024 18.4 0.5 0.014 16.0 0.2 2.5 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Brix PF04427.18 GAM39655.1 - 2.3e-52 178.0 0.4 3.1e-52 177.5 0.4 1.2 1 0 0 1 1 1 1 Brix domain Lum_binding PF00677.17 GAM39656.1 - 4.2e-44 148.4 1.4 1.9e-22 79.0 0.2 2.3 2 0 0 2 2 2 2 Lumazine binding domain CoA_transf_3 PF02515.17 GAM39657.1 - 1e-126 423.0 0.0 1.2e-126 422.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III PHD PF00628.29 GAM39658.1 - 8.8e-11 41.5 9.9 1.4e-10 40.8 9.9 1.4 1 0 0 1 1 1 1 PHD-finger FYVE_2 PF02318.16 GAM39658.1 - 0.048 13.9 3.0 0.079 13.2 3.0 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_1 PF14446.6 GAM39658.1 - 0.3 11.1 6.1 0.72 9.8 6.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 GAM39658.1 - 0.84 9.8 6.8 1.9 8.7 6.8 1.6 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 GAM39658.1 - 0.9 9.5 8.0 0.13 12.1 3.3 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_7 PF02591.15 GAM39658.1 - 1.5 9.1 3.2 50 4.2 0.2 3.0 2 0 0 2 2 2 0 C4-type zinc ribbon domain ADK_lid PF05191.14 GAM39658.1 - 1.7 8.7 8.3 0.4 10.7 1.3 3.1 3 0 0 3 3 3 0 Adenylate kinase, active site lid PHD_2 PF13831.6 GAM39658.1 - 1.7 8.3 11.8 0.1 12.1 6.1 2.0 2 1 0 2 2 2 0 PHD-finger DDE_Tnp_1_7 PF13843.6 GAM39659.1 - 1.4e-21 77.2 0.1 2e-21 76.7 0.1 1.2 1 0 0 1 1 1 1 Transposase IS4 Tnp_zf-ribbon_2 PF13842.6 GAM39659.1 - 0.00019 22.1 4.6 0.00036 21.3 4.6 1.5 1 0 0 1 1 1 1 DDE_Tnp_1-like zinc-ribbon adh_short PF00106.25 GAM39660.1 - 3.4e-30 105.0 0.0 1.7e-29 102.7 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase MFS_1 PF07690.16 GAM39660.1 - 8.3e-22 77.6 52.1 2.3e-21 76.1 46.5 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 GAM39660.1 - 3.4e-21 75.9 0.0 1.7e-20 73.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase TRI12 PF06609.13 GAM39660.1 - 3.7e-12 45.5 25.7 5.4e-12 44.9 25.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) KR PF08659.10 GAM39660.1 - 3.4e-09 36.9 0.0 6.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF962 PF06127.11 GAM39660.1 - 0.013 15.6 0.0 0.59 10.3 0.0 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF962) DUF1776 PF08643.10 GAM39660.1 - 0.02 14.2 0.0 0.057 12.8 0.0 1.7 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2933 PF11666.8 GAM39660.1 - 0.098 12.7 0.5 0.31 11.1 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) DUF2583 PF10762.9 GAM39660.1 - 8.7 6.8 7.4 4.1 7.9 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2583) Zn_clus PF00172.18 GAM39661.1 - 8.7e-10 38.6 5.3 1.4e-09 37.9 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM39661.1 - 4e-05 22.8 0.2 5.6e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_2 PF04909.14 GAM39662.1 - 1.1e-34 120.5 0.0 1.3e-34 120.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 GAM39662.1 - 0.0031 17.0 0.0 0.07 12.5 0.0 2.3 2 1 0 2 2 2 1 TatD related DNase Lactamase_B PF00753.27 GAM39663.1 - 2.3e-08 34.3 1.6 5e-08 33.2 1.6 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM39663.1 - 0.0045 16.5 0.2 0.009 15.5 0.1 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAM39663.1 - 0.071 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain adh_short PF00106.25 GAM39664.1 - 2e-33 115.5 0.0 2.8e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM39664.1 - 1.6e-25 90.1 0.0 2.6e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM39664.1 - 4.7e-08 33.2 0.2 9.7e-08 32.1 0.2 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAM39664.1 - 0.00042 19.8 0.1 0.00072 19.0 0.1 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Sof1 PF04158.14 GAM39665.1 - 3.3e-28 97.8 13.2 5.7e-28 97.0 13.2 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 GAM39665.1 - 5.3e-27 93.5 2.3 8e-05 23.3 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM39665.1 - 1.7e-08 34.7 0.0 0.017 15.4 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM39665.1 - 4.7e-05 22.5 0.1 0.012 14.6 0.0 3.1 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 GAM39665.1 - 0.00061 19.8 0.0 17 5.5 0.0 3.6 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 GAM39665.1 - 0.0034 17.3 1.4 0.57 10.0 0.1 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAM39665.1 - 0.34 9.5 6.7 1.4 7.5 2.8 2.8 2 1 0 2 2 2 0 Nucleoporin Nup120/160 RPN6_N PF18055.1 GAM39666.1 - 1.5e-44 151.1 0.4 6.2e-44 149.1 0.4 2.1 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 GAM39666.1 - 2e-21 76.5 0.0 9.8e-21 74.2 0.1 2.1 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 GAM39666.1 - 2.8e-10 39.8 0.2 2.8e-10 39.8 0.2 2.1 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 GAM39666.1 - 2.8e-06 27.5 16.0 0.0023 18.2 1.3 5.2 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM39666.1 - 1.2e-05 24.9 3.6 1.2e-05 24.9 3.6 2.4 2 1 0 2 2 2 1 MalT-like TPR region DDRGK PF09756.9 GAM39666.1 - 1.4e-05 24.8 0.2 2.8e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 DDRGK domain DprA_WH PF17782.1 GAM39666.1 - 0.0071 16.4 0.1 0.32 11.1 0.0 3.1 3 0 0 3 3 3 1 DprA winged helix domain HTH_Crp_2 PF13545.6 GAM39666.1 - 0.022 14.7 0.1 0.37 10.8 0.0 2.9 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain INT_SG_DDX_CT_C PF15300.6 GAM39666.1 - 0.085 12.7 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Prefoldin_2 PF01920.20 GAM39666.1 - 0.087 12.8 0.9 0.62 10.0 0.4 2.7 2 0 0 2 2 2 0 Prefoldin subunit TPR_1 PF00515.28 GAM39666.1 - 2.3 8.2 11.8 1.8 8.5 0.1 5.0 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM39666.1 - 2.6 8.5 10.2 1e+02 3.5 0.1 6.1 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM39666.1 - 3.4 8.0 12.8 39 4.7 0.6 5.7 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM39666.1 - 8.3 7.0 10.8 6.2 7.4 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat SWIB PF02201.18 GAM39667.1 - 1.1e-19 70.1 0.0 2.3e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain TRAM_LAG1_CLN8 PF03798.16 GAM39668.1 - 1.2e-54 185.1 15.4 1.2e-54 185.1 15.4 1.9 2 0 0 2 2 2 1 TLC domain DUF810 PF05664.11 GAM39668.1 - 0.027 13.0 0.1 2.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Plant family of unknown function (DUF810) P5CR_dimer PF14748.6 GAM39669.1 - 0.08 13.2 5.1 5.8 7.2 0.1 4.4 1 1 2 3 3 3 0 Pyrroline-5-carboxylate reductase dimerisation PI_PP_C PF18365.1 GAM39669.1 - 0.21 11.5 3.0 1.2 9.1 0.1 3.9 4 0 0 4 4 4 0 Phosphoinositide phosphatase C-terminal domain Ribosomal_L27e PF01777.18 GAM39670.1 - 1e-36 125.1 1.9 2.3e-36 124.0 1.9 1.6 1 0 0 1 1 1 1 Ribosomal L27e protein family SQS_PSY PF00494.19 GAM39670.1 - 1.3e-30 106.8 0.0 1.9e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase KOW PF00467.29 GAM39670.1 - 0.031 14.2 1.4 0.076 13.0 0.4 2.2 2 0 0 2 2 2 0 KOW motif PhyH PF05721.13 GAM39671.1 - 2.1e-20 73.9 0.0 3.2e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pyr_redox_2 PF07992.14 GAM39672.1 - 3.1e-05 23.4 0.0 0.00056 19.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 GAM39672.1 - 0.0015 18.6 0.0 0.0037 17.3 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 GAM39672.1 - 0.0071 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Ribosomal_S2 PF00318.20 GAM39672.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 FMO-like PF00743.19 GAM39672.1 - 0.019 13.4 0.0 0.037 12.4 0.0 1.4 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like DUF498 PF04430.14 GAM39672.1 - 0.041 14.0 0.0 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) NAD_binding_7 PF13241.6 GAM39672.1 - 0.047 14.1 0.0 0.099 13.1 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 GAM39672.1 - 0.16 11.2 0.0 1 8.6 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Perilipin PF03036.16 GAM39673.1 - 0.13 11.2 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Perilipin family Band_7 PF01145.25 GAM39674.1 - 2.2e-27 96.2 3.3 3.9e-27 95.4 3.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 GAM39674.1 - 0.03 14.1 0.2 0.046 13.4 0.2 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family PARP PF00644.20 GAM39675.1 - 8.5e-11 41.8 1.0 8.5e-11 41.8 1.0 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 GAM39675.1 - 6.1e-07 29.2 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RNA_pol_Rpb4 PF03874.16 GAM39678.1 - 1.1e-07 32.2 0.2 0.00089 19.6 0.0 2.3 2 1 0 2 2 2 2 RNA polymerase Rpb4 Nop PF01798.18 GAM39679.1 - 2.3e-83 279.2 0.2 4.9e-83 278.1 0.2 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 GAM39679.1 - 9.1e-23 80.4 0.6 9.1e-23 80.4 0.6 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain vATP-synt_AC39 PF01992.16 GAM39680.1 - 5.1e-105 351.7 0.0 5.8e-105 351.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Pribosyl_synth PF14572.6 GAM39681.1 - 4.5e-41 140.9 1.8 2.7e-35 122.1 0.8 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 GAM39681.1 - 7.1e-34 116.2 0.0 2.2e-33 114.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 GAM39681.1 - 2.2e-14 53.3 0.3 4e-14 52.4 0.3 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAM39681.1 - 0.00043 19.8 0.1 0.00075 19.0 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ubiquitin PF00240.23 GAM39682.1 - 0.0019 17.9 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 GAM39682.1 - 0.0021 18.7 0.0 0.0034 18.0 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD PseudoU_synth_1 PF01416.20 GAM39683.1 - 9.2e-35 119.4 0.0 3e-33 114.5 0.0 2.6 2 0 0 2 2 2 1 tRNA pseudouridine synthase Pox_A_type_inc PF04508.12 GAM39683.1 - 0.033 14.0 0.1 0.08 12.8 0.1 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Ribosomal_S2 PF00318.20 GAM39684.1 - 3e-26 92.0 0.1 8.6e-15 54.6 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 GAM39684.1 - 8e-08 33.5 12.0 1.5e-07 32.7 12.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S15 PF00312.22 GAM39685.1 - 1e-26 92.9 4.0 1.1e-26 92.9 0.3 2.7 2 1 1 3 3 3 1 Ribosomal protein S15 ATP-synt_G PF04718.15 GAM39686.1 - 0.16 12.8 4.1 1.4 9.8 4.1 2.7 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit MFS_1 PF07690.16 GAM39687.1 - 8.7e-42 143.3 57.9 4.8e-31 108.0 37.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM39687.1 - 7.5e-09 35.0 29.1 3.4e-05 22.9 6.7 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter DEAD PF00270.29 GAM39688.1 - 2.3e-37 128.5 0.0 7.3e-37 126.8 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM39688.1 - 6.7e-23 81.2 0.0 1.6e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAM39688.1 - 1.1e-20 73.7 0.2 2.2e-20 72.6 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAM39688.1 - 0.0038 17.2 0.0 0.019 15.0 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAM39688.1 - 0.019 14.2 1.3 0.031 13.5 0.0 1.9 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase UvrD-helicase PF00580.21 GAM39688.1 - 0.85 9.1 9.8 1.5 8.3 0.0 2.6 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Borrelia_P83 PF05262.11 GAM39688.1 - 0.92 7.9 15.4 1.3 7.4 15.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_11 PF13086.6 GAM39688.1 - 1.1 9.0 6.8 2.4 7.9 5.5 2.2 2 0 0 2 2 2 0 AAA domain XPG_I PF00867.18 GAM39690.1 - 1.6e-23 82.8 0.0 3.5e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 GAM39690.1 - 1e-22 81.0 0.4 1e-22 81.0 0.4 3.2 2 1 1 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 GAM39690.1 - 9e-07 29.3 0.0 2.5e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain Actin PF00022.19 GAM39691.1 - 6.6e-26 90.8 0.0 1.1e-16 60.5 0.0 2.6 3 0 0 3 3 3 2 Actin MreB_Mbl PF06723.13 GAM39691.1 - 0.0065 15.3 0.0 0.094 11.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Aldose_epim PF01263.20 GAM39692.1 - 7.4e-48 163.4 0.2 9.8e-48 163.0 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase AT_hook PF02178.19 GAM39693.1 - 0.046 13.6 17.7 1.2 9.3 4.1 3.0 2 0 0 2 2 2 0 AT hook motif Pkinase PF00069.25 GAM39694.1 - 2.5e-12 46.8 0.0 2.4e-09 37.0 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM39694.1 - 2.9e-09 36.6 0.0 1.6e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM39694.1 - 0.099 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Nucleo_P87 PF07267.11 GAM39694.1 - 0.15 10.9 12.2 0.24 10.2 12.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Borrelia_REV PF03978.13 GAM39694.1 - 0.62 10.0 2.2 1.2 9.1 2.2 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Glyco_hydro_72 PF03198.14 GAM39695.1 - 6.3e-101 337.8 0.3 8.5e-101 337.3 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Zn_clus PF00172.18 GAM39697.1 - 8.7e-06 25.8 11.3 1.7e-05 24.8 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 GAM39697.1 - 0.00019 20.1 0.0 0.0012 17.4 0.0 2.0 1 1 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B ZapB PF06005.12 GAM39697.1 - 4.9 7.7 10.6 2.4 8.7 4.9 2.5 2 0 0 2 2 2 0 Cell division protein ZapB Sugar_tr PF00083.24 GAM39698.1 - 9.3e-40 136.8 7.0 8.7e-29 100.7 0.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM39698.1 - 2.3e-11 43.2 15.1 4.2e-07 29.2 1.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 GAM39698.1 - 0.12 12.6 0.7 0.12 12.6 0.7 3.4 4 0 0 4 4 4 0 Transglycosylase associated protein TPR_3 PF07720.12 GAM39698.1 - 0.2 11.7 0.0 0.38 10.8 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Rick_17kDa_Anti PF05433.15 GAM39698.1 - 0.41 10.6 3.2 6.1 6.8 0.6 2.7 2 1 0 2 2 2 0 Glycine zipper 2TM domain PgaD PF13994.6 GAM39699.1 - 0.16 12.0 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein DUF3780 PF12635.7 GAM39700.1 - 0.059 13.1 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3780) Sds3 PF08598.11 GAM39702.1 - 3.4e-46 158.0 0.7 1.8e-44 152.4 0.7 2.1 1 1 0 1 1 1 1 Sds3-like DUF3823 PF12866.7 GAM39702.1 - 0.098 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3823) N-terminal domain DUF3433 PF11915.8 GAM39704.1 - 1.3e-43 147.4 7.3 1.6e-23 83.0 1.1 3.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) CFEM PF05730.11 GAM39705.1 - 3.9e-05 23.7 7.3 3.9e-05 23.7 7.3 3.2 4 0 0 4 4 4 1 CFEM domain CRF1 PF10380.9 GAM39706.1 - 0.023 15.0 0.2 0.023 15.0 0.2 3.0 3 1 0 3 3 3 0 Transcription factor CRF1 DUF2752 PF10825.8 GAM39707.1 - 0.03 14.4 0.4 0.049 13.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Med3 PF11593.8 GAM39707.1 - 1.9 7.6 10.3 4.2 6.5 10.3 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal BTB PF00651.31 GAM39709.1 - 2.1e-08 34.4 0.1 1.2e-07 32.0 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain Skp1_POZ PF03931.15 GAM39709.1 - 0.069 13.3 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain ABC_tran PF00005.27 GAM39710.1 - 7.4e-51 172.3 0.1 7.1e-26 91.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 GAM39710.1 - 1.9e-46 158.1 37.2 2.6e-27 95.6 11.5 2.6 3 0 0 3 3 2 2 ABC-2 type transporter Abhydrolase_3 PF07859.13 GAM39710.1 - 1.4e-25 90.4 0.0 2.8e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold AAA_21 PF13304.6 GAM39710.1 - 1.1e-11 45.1 0.3 0.019 14.8 0.0 4.4 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAM39710.1 - 1.3e-09 38.2 0.3 0.0022 17.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 GAM39710.1 - 7.9e-08 32.9 0.1 0.0083 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 GAM39710.1 - 3.8e-07 29.8 0.2 0.092 12.2 0.0 3.9 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAM39710.1 - 1.4e-06 29.0 4.4 0.0017 18.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 GAM39710.1 - 3.7e-06 26.6 1.6 0.086 12.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GAM39710.1 - 2.3e-05 24.7 0.1 0.21 11.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain ATPase_2 PF01637.18 GAM39710.1 - 0.00029 20.8 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 GAM39710.1 - 0.00037 20.4 0.5 0.22 11.4 0.1 2.8 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 GAM39710.1 - 0.00046 19.9 0.4 0.52 10.0 0.1 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 GAM39710.1 - 0.00061 19.9 2.7 0.33 11.1 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 GAM39710.1 - 0.00079 19.1 1.3 0.45 10.1 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 GAM39710.1 - 0.00083 19.8 3.5 0.62 10.5 0.0 3.0 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAM39710.1 - 0.0011 19.3 0.3 0.79 10.1 0.1 2.7 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 GAM39710.1 - 0.0014 18.3 0.0 0.9 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAM39710.1 - 0.0025 17.6 0.0 2.9 7.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 GAM39710.1 - 0.0054 15.8 0.2 0.26 10.3 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_15 PF13175.6 GAM39710.1 - 0.0055 16.5 0.1 4.5 6.9 0.1 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 GAM39710.1 - 0.0078 16.8 0.0 0.48 11.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAM39710.1 - 0.0084 16.1 0.3 1.4 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 GAM39710.1 - 0.0096 16.2 4.3 0.87 9.8 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 GAM39710.1 - 0.013 15.6 0.4 1.2 9.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain PDR_CDR PF06422.12 GAM39710.1 - 0.028 14.3 0.2 0.11 12.4 0.2 2.0 1 0 0 1 1 1 0 CDR ABC transporter Roc PF08477.13 GAM39710.1 - 0.03 14.5 0.6 11 6.3 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 GAM39710.1 - 0.036 14.0 0.4 4 7.3 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 GAM39710.1 - 0.073 13.4 0.7 16 5.8 0.1 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAM39710.1 - 0.083 12.8 0.3 12 5.7 0.0 2.6 2 0 0 2 2 2 0 NTPase PhoH PF02562.16 GAM39710.1 - 0.089 12.2 0.1 9.9 5.5 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein PGA_cap PF09587.10 GAM39710.1 - 0.097 12.1 0.0 0.76 9.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap AAA_11 PF13086.6 GAM39710.1 - 0.12 12.2 0.1 2.9 7.6 0.0 2.5 3 0 0 3 3 2 0 AAA domain Say1_Mug180 PF10340.9 GAM39710.1 - 0.13 11.1 0.1 0.67 8.8 0.0 2.1 2 1 0 2 2 2 0 Steryl acetyl hydrolase Zeta_toxin PF06414.12 GAM39710.1 - 0.15 11.3 0.8 11 5.3 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 GAM39710.1 - 0.19 11.4 0.1 30 4.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.12 GAM39710.1 - 0.38 10.2 1.3 15 4.9 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_7 PF12775.7 GAM39710.1 - 0.48 9.9 1.7 12 5.3 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region Dynamin_N PF00350.23 GAM39710.1 - 0.56 10.2 3.4 13 5.8 0.3 2.6 2 0 0 2 2 2 0 Dynamin family PRK PF00485.18 GAM39710.1 - 0.67 9.7 2.6 12 5.6 0.3 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DnaJ PF00226.31 GAM39711.1 - 3.2e-09 36.8 2.4 3.2e-09 36.8 2.4 2.4 2 1 0 2 2 2 1 DnaJ domain DUF4834 PF16118.5 GAM39711.1 - 0.17 12.9 0.0 0.39 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FHA PF00498.26 GAM39712.1 - 7.1e-15 55.1 0.0 1.9e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAM39712.1 - 0.074 13.4 0.0 1.6 9.1 0.0 2.3 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Apt1 PF10351.9 GAM39712.1 - 8 5.2 14.2 10 4.9 14.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DivIVA PF05103.13 GAM39713.1 - 0.046 13.8 1.1 0.053 13.6 1.1 1.1 1 0 0 1 1 1 0 DivIVA protein CsbD PF05532.12 GAM39713.1 - 0.083 12.8 10.6 4.3 7.3 10.1 2.7 1 1 0 1 1 1 0 CsbD-like DUF883 PF05957.13 GAM39713.1 - 0.21 12.2 5.3 0.44 11.2 2.2 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) NB-ARC PF00931.22 GAM39714.1 - 4.1e-11 42.5 0.0 6.7e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 GAM39714.1 - 2.4e-05 24.8 0.0 7.2e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM39714.1 - 7.6e-05 23.0 0.0 0.00025 21.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.14 GAM39714.1 - 8.7e-05 22.1 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Zeta_toxin PF06414.12 GAM39714.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.12 GAM39714.1 - 0.0015 18.3 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain PGAP1 PF07819.13 GAM39714.1 - 0.0098 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein AAA_33 PF13671.6 GAM39714.1 - 0.013 15.7 0.0 0.064 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAM39714.1 - 0.024 14.4 0.0 0.083 12.6 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 GAM39714.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 NACHT domain ATPase PF06745.13 GAM39714.1 - 0.076 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 GAM39714.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAM39714.1 - 0.11 13.0 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 GAM39714.1 - 0.2 11.1 0.0 0.43 10.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ECH_1 PF00378.20 GAM39715.1 - 2e-39 135.4 0.0 3.6e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM39715.1 - 2.2e-28 99.7 0.0 3.6e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase YqjK PF13997.6 GAM39715.1 - 0.067 13.4 0.5 0.45 10.8 0.2 2.5 2 0 0 2 2 2 0 YqjK-like protein DUF3512 PF12024.8 GAM39716.1 - 0.0071 15.9 0.2 0.0071 15.9 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) GatB_N PF02934.15 GAM39718.1 - 3.9e-97 324.9 0.0 5.3e-97 324.5 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 GAM39718.1 - 7.1e-26 90.9 0.3 1.2e-25 90.1 0.3 1.4 1 0 0 1 1 1 1 GatB domain Arginase PF00491.21 GAM39719.1 - 6e-76 255.6 0.5 1.1e-75 254.8 0.5 1.4 1 0 0 1 1 1 1 Arginase family NIF PF03031.18 GAM39719.1 - 7.5e-28 97.3 0.2 1.8e-27 96.0 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 GAM39719.1 - 9.4e-08 32.3 0.0 2.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAM39719.1 - 0.00016 22.0 0.0 0.00099 19.5 0.0 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 GAM39719.1 - 0.00059 19.7 0.1 0.0019 18.1 0.1 1.9 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 GAM39719.1 - 0.15 11.9 0.0 0.47 10.3 0.0 1.9 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain MT0933_antitox PF14013.6 GAM39720.1 - 0.032 14.5 0.7 0.073 13.4 0.2 1.8 1 1 1 2 2 2 0 MT0933-like antitoxin protein MARVEL PF01284.23 GAM39721.1 - 1.3e-05 25.2 14.4 2.5e-05 24.3 14.4 1.5 1 1 0 1 1 1 1 Membrane-associating domain Asp PF00026.23 GAM39722.1 - 4.9e-109 364.6 0.1 5.7e-109 364.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM39722.1 - 9.7e-17 61.8 2.0 1e-14 55.2 1.6 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAM39722.1 - 3e-05 24.6 0.1 0.22 12.2 0.0 3.1 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 GAM39722.1 - 0.00043 20.8 0.0 0.42 11.2 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 GAM39722.1 - 0.011 15.6 0.0 0.17 11.7 0.0 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal AAA PF00004.29 GAM39723.1 - 7.3e-45 152.6 0.6 2.4e-44 151.0 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAM39723.1 - 2.7e-10 40.0 0.1 2.1e-09 37.2 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 GAM39723.1 - 2e-08 34.3 0.1 7.4e-08 32.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAM39723.1 - 1.1e-07 32.2 0.0 2.3e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAM39723.1 - 1.5e-07 31.9 0.4 3e-05 24.5 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 GAM39723.1 - 3.2e-06 26.5 0.0 7.2e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 GAM39723.1 - 4.9e-05 23.6 0.8 0.0081 16.4 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 GAM39723.1 - 0.00019 21.1 0.0 0.00045 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 GAM39723.1 - 0.00037 20.3 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 GAM39723.1 - 0.00054 19.5 0.0 0.007 15.9 0.1 2.5 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 GAM39723.1 - 0.00066 19.7 0.0 0.0024 17.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM39723.1 - 0.00067 20.2 0.0 0.0021 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAM39723.1 - 0.00084 19.6 0.1 0.002 18.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 GAM39723.1 - 0.0014 19.0 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 GAM39723.1 - 0.0026 17.7 0.0 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 GAM39723.1 - 0.0036 17.1 0.2 0.011 15.5 0.2 1.9 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 GAM39723.1 - 0.0042 17.1 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 GAM39723.1 - 0.005 16.1 0.0 0.0092 15.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 GAM39723.1 - 0.0058 16.8 0.0 0.021 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 GAM39723.1 - 0.0065 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 GAM39723.1 - 0.007 15.8 0.0 0.36 10.2 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 GAM39723.1 - 0.0084 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAM39723.1 - 0.0094 15.7 0.1 0.034 13.9 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.12 GAM39723.1 - 0.014 15.4 1.2 0.11 12.4 0.0 2.7 3 1 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 GAM39723.1 - 0.021 14.6 0.2 0.051 13.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 GAM39723.1 - 0.044 13.6 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAM39723.1 - 0.045 13.7 0.7 0.22 11.4 0.1 2.4 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 GAM39723.1 - 0.063 12.9 1.0 0.3 10.6 0.1 2.2 2 1 1 3 3 3 0 AAA domain Bac_DnaA PF00308.18 GAM39723.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 GAM39723.1 - 0.12 12.1 0.1 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 GAM39723.1 - 0.14 12.5 0.1 0.39 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 GAM39723.1 - 0.21 10.6 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ARID PF01388.21 GAM39724.1 - 5.5e-20 71.8 0.0 1.3e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain eIF3_N PF09440.10 GAM39725.1 - 1.7e-50 170.9 1.1 5.4e-50 169.3 1.1 1.9 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 GAM39725.1 - 3.7e-14 53.1 0.0 9.6e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 PCI domain ArsA_ATPase PF02374.15 GAM39727.1 - 1.4e-112 375.9 0.0 1.4e-112 375.9 0.0 3.8 3 0 0 3 3 3 1 Anion-transporting ATPase ATG11 PF10377.9 GAM39727.1 - 5.7e-44 149.3 0.1 5.7e-44 149.3 0.1 4.8 5 0 0 5 5 5 1 Autophagy-related protein 11 AAA_31 PF13614.6 GAM39727.1 - 2.1e-11 44.0 0.0 2.1e-11 44.0 0.0 3.6 3 1 0 4 4 4 1 AAA domain CbiA PF01656.23 GAM39727.1 - 5.4e-11 42.7 4.5 5.6e-11 42.6 0.0 3.3 3 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 GAM39727.1 - 0.00011 21.8 0.0 0.00011 21.8 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 GAM39727.1 - 0.00028 20.4 0.4 0.0017 17.9 0.0 2.6 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 GAM39727.1 - 0.00039 19.9 1.0 0.0012 18.3 0.1 2.2 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 GAM39727.1 - 0.00075 19.2 2.8 0.0043 16.7 0.0 3.1 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CENP-H PF05837.12 GAM39728.1 - 2.9e-31 108.2 4.3 2.9e-31 108.2 4.3 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) Tom5 PF10642.9 GAM39728.1 - 0.13 12.3 1.0 0.77 9.8 0.2 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase HMG_box PF00505.19 GAM39729.1 - 8.3e-24 83.8 0.1 1.1e-23 83.4 0.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAM39729.1 - 2.2e-15 57.0 0.3 3.3e-15 56.4 0.3 1.2 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 GAM39729.1 - 0.24 12.0 0.1 0.34 11.5 0.1 1.3 1 0 0 1 1 1 0 YABBY protein GLTP PF08718.11 GAM39730.1 - 1.1e-41 142.6 0.1 2e-41 141.8 0.1 1.5 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) E1-E2_ATPase PF00122.20 GAM39730.1 - 1.2e-19 70.5 0.1 3.7e-19 68.9 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAM39730.1 - 2.3e-13 50.9 3.8 1.9e-07 31.6 3.2 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAM39730.1 - 0.0056 16.5 0.1 0.027 14.2 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM39730.1 - 0.0057 16.7 0.2 0.082 13.0 0.0 2.6 3 0 0 3 3 3 1 Cation transport ATPase (P-type) S6PP PF05116.13 GAM39730.1 - 0.01 15.4 0.1 0.059 12.9 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase PH_4 PF15404.6 GAM39731.1 - 1.6e-56 191.0 0.2 3e-55 186.9 0.2 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.6 GAM39731.1 - 2.2e-23 81.6 2.2 2.2e-23 81.6 2.2 2.0 2 0 0 2 2 2 1 Sporulation protein family 7 PH PF00169.29 GAM39731.1 - 1.6e-13 51.0 0.4 0.00021 21.8 0.0 5.5 4 1 0 4 4 4 3 PH domain PH_6 PF15406.6 GAM39731.1 - 0.11 12.8 0.0 3.6 7.9 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain PH_13 PF16652.5 GAM39731.1 - 0.29 11.0 1.6 4 7.2 0.1 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain Peptidase_S24 PF00717.23 GAM39732.1 - 1.2e-07 31.6 0.0 5.3e-07 29.5 0.0 2.1 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 GAM39732.1 - 0.003 17.4 0.0 3.7 7.3 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Macro PF01661.21 GAM39733.1 - 4.1e-40 136.5 0.0 6.2e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 Macro domain Ank_4 PF13637.6 GAM39735.1 - 1.5e-11 44.6 0.2 4.8e-05 23.8 0.0 3.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM39735.1 - 3.7e-10 40.3 0.0 0.00011 22.8 0.0 2.9 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 GAM39735.1 - 1.1e-09 38.3 0.0 7.7e-07 29.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 GAM39735.1 - 1.2e-08 34.5 0.2 0.00015 21.9 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAM39735.1 - 4.5e-07 30.0 0.1 0.00012 22.3 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) KilA-N PF04383.13 GAM39735.1 - 4.6e-05 23.2 0.3 0.00022 21.0 0.0 2.2 2 1 0 2 2 2 1 KilA-N domain NDUF_B7 PF05676.13 GAM39736.1 - 1.7e-30 104.5 5.9 2.1e-30 104.2 5.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 GAM39736.1 - 0.0076 16.2 1.0 0.011 15.8 1.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCS PF03074.16 GAM39737.1 - 2.6e-177 589.7 0.0 3.2e-177 589.4 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Cytochrom_B561 PF03188.16 GAM39737.1 - 0.2 11.8 0.0 4.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 GATA PF00320.27 GAM39738.1 - 2.9e-15 55.6 5.3 5.1e-15 54.8 5.3 1.4 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 GAM39738.1 - 0.38 11.1 1.6 0.76 10.1 1.6 1.4 1 0 0 1 1 1 0 zinc-ribbon ThrE PF06738.12 GAM39739.1 - 8.2e-75 251.3 11.5 1.7e-69 233.9 2.4 2.4 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 GAM39739.1 - 1.1e-08 35.3 9.6 1.1e-08 35.3 9.6 3.2 3 1 0 3 3 3 1 Threonine/Serine exporter, ThrE MIS13 PF08202.11 GAM39740.1 - 1.2e-51 175.9 0.1 2.1e-51 175.0 0.1 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family DivIC PF04977.15 GAM39740.1 - 0.066 13.0 0.4 0.14 11.9 0.4 1.5 1 0 0 1 1 1 0 Septum formation initiator Takusan PF04822.13 GAM39740.1 - 0.15 12.0 1.2 0.41 10.5 1.2 1.7 1 0 0 1 1 1 0 Takusan ABC_tran_CTD PF16326.5 GAM39740.1 - 0.17 12.2 1.5 0.53 10.6 1.5 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain PS_Dcarbxylase PF02666.15 GAM39741.1 - 5.2e-57 192.6 0.0 8.3e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 GAM39741.1 - 4.1e-40 136.2 0.0 2.4e-19 69.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_5 PF13202.6 GAM39741.1 - 0.094 12.2 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 EF hand Sugar_tr PF00083.24 GAM39742.1 - 6.2e-92 308.8 9.7 8.9e-92 308.3 9.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM39742.1 - 1.9e-35 122.4 61.5 3.7e-31 108.4 30.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 GAM39742.1 - 2.1e-08 33.9 3.5 2.1e-08 33.9 3.5 3.1 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 GAM39742.1 - 0.00013 20.5 1.6 0.00013 20.5 1.6 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 GAM39742.1 - 0.0076 14.6 1.5 0.049 11.9 1.5 2.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family CfAFP PF05264.11 GAM39743.1 - 0.38 10.7 1.9 0.72 9.8 0.2 2.2 3 0 0 3 3 3 0 Choristoneura fumiferana antifreeze protein (CfAFP) PAN_4 PF14295.6 GAM39744.1 - 0.00029 20.7 2.1 0.00072 19.4 2.1 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 GAM39744.1 - 0.0019 18.1 2.5 0.0037 17.2 2.5 1.4 1 0 0 1 1 1 1 PAN domain Fringe PF02434.16 GAM39744.1 - 0.0036 16.8 1.4 0.051 13.0 1.4 2.2 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.12 GAM39744.1 - 0.11 11.9 0.3 0.42 10.0 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF604 SKG6 PF08693.10 GAM39745.1 - 8.8e-06 25.0 0.8 1.6e-05 24.2 0.8 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain GPI-anchored PF10342.9 GAM39745.1 - 0.00026 21.7 4.5 0.00034 21.3 0.0 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family VSP PF03302.13 GAM39745.1 - 0.0014 17.6 0.6 0.0019 17.1 0.6 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF347 PF03988.12 GAM39745.1 - 0.017 15.3 0.6 0.044 14.0 0.6 1.7 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) PGF-CTERM PF18204.1 GAM39745.1 - 0.04 13.9 2.2 0.067 13.2 2.2 1.4 1 0 0 1 1 1 0 PGF-CTERM motif DUF4448 PF14610.6 GAM39745.1 - 0.051 13.3 0.0 0.083 12.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) MFS_1 PF07690.16 GAM39746.1 - 2.2e-40 138.7 28.2 2.2e-40 138.7 28.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM39746.1 - 3.9e-15 55.7 1.6 3.9e-15 55.7 1.6 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Sugar_tr PF00083.24 GAM39747.1 - 1.3e-115 386.9 28.2 1.5e-115 386.7 28.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM39747.1 - 6.1e-25 87.9 51.3 3.6e-20 72.2 25.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MCM PF00493.23 GAM39748.1 - 9.2e-101 335.6 0.0 1.4e-100 335.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAM39748.1 - 6.5e-39 132.7 0.2 1.2e-38 131.8 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 GAM39748.1 - 1e-29 103.8 36.3 1e-29 103.8 36.3 2.0 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 GAM39748.1 - 1.3e-24 86.4 0.8 4.1e-24 84.8 0.8 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAM39748.1 - 7.3e-11 42.6 0.0 2.2e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAM39748.1 - 7e-09 35.4 0.1 3.2e-06 26.7 0.0 2.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAM39748.1 - 5.4e-06 26.4 0.0 1.4e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAM39748.1 - 0.00027 20.8 0.0 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAM39748.1 - 0.0011 18.7 0.2 0.0074 16.0 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 GAM39748.1 - 2.7 8.4 6.5 0.26 11.6 0.3 2.6 2 1 0 2 2 2 0 AAA ATPase domain Cathelicidins PF00666.17 GAM39749.1 - 0.027 14.8 2.9 0.028 14.7 0.7 2.1 2 0 0 2 2 2 0 Cathelicidin zf-UBR PF02207.20 GAM39749.1 - 0.35 11.1 16.0 0.037 14.2 3.5 4.1 4 1 0 4 4 4 0 Putative zinc finger in N-recognin (UBR box) Tim54 PF11711.8 GAM39749.1 - 6.6 5.4 6.9 0.99 8.1 2.1 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.25 GAM39750.1 - 1.8e-62 211.1 0.0 2.2e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM39750.1 - 6e-29 101.1 0.0 9.1e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAM39750.1 - 0.0022 17.0 0.2 0.0034 16.4 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAM39750.1 - 0.2 11.6 0.0 0.68 9.8 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family ERCC4 PF02732.15 GAM39751.1 - 3.2e-20 72.9 0.0 9.4e-20 71.4 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain DUF4780 PF16012.5 GAM39751.1 - 0.0018 17.8 0.0 6.2 6.2 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4780) HHH_5 PF14520.6 GAM39751.1 - 0.018 15.7 0.0 0.047 14.3 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain eIF-1a PF01176.19 GAM39753.1 - 7.9e-23 80.1 0.1 1.1e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 fn3_2 PF16893.5 GAM39755.1 - 2.9e-38 129.9 0.1 4.8e-38 129.2 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 GAM39755.1 - 1.4e-24 85.8 0.3 2.5e-24 84.9 0.3 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 GAM39755.1 - 1.9e-13 50.1 0.0 3.3e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 GAM39755.1 - 3.6e-09 36.9 0.0 6.5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAM39755.1 - 2.8e-06 27.6 0.0 5.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 GAM39755.1 - 7.9e-05 22.8 0.0 0.00027 21.1 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.21 GAM39755.1 - 0.0035 17.7 0.0 0.013 15.8 0.0 2.0 1 1 0 1 1 1 1 Fibronectin type III domain DUF3500 PF12006.8 GAM39756.1 - 2.8e-111 371.8 0.0 3.4e-111 371.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) SEN1_N PF12726.7 GAM39758.1 - 6.1e-213 709.2 5.4 8e-213 708.8 5.4 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 GAM39758.1 - 4.3e-72 243.0 2.3 4.3e-72 243.0 2.3 2.6 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 GAM39758.1 - 2.3e-60 203.6 0.0 4.3e-60 202.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM39758.1 - 4e-10 39.7 0.3 3.8e-06 26.8 0.3 2.6 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 GAM39758.1 - 1.2e-08 34.9 4.4 1.1e-06 28.4 1.5 3.4 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 GAM39758.1 - 1.6e-07 31.8 0.0 5.7e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 GAM39758.1 - 4.9e-07 29.7 0.1 0.031 14.0 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase zf-CCHC PF00098.23 GAM39758.1 - 0.0001 22.2 16.7 0.17 12.0 2.0 3.5 3 0 0 3 3 3 3 Zinc knuckle DEAD PF00270.29 GAM39758.1 - 0.0041 16.9 0.4 0.011 15.5 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SSE PF00437.20 GAM39758.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 GAM39758.1 - 0.054 13.5 0.1 0.22 11.5 0.1 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CLIP1_ZNF PF16641.5 GAM39758.1 - 0.13 12.2 3.5 0.35 10.8 3.5 1.8 1 0 0 1 1 1 0 CLIP1 zinc knuckle RPN6_C_helix PF18503.1 GAM39758.1 - 0.15 11.8 0.0 0.4 10.5 0.0 1.8 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain SF1-HH PF16275.5 GAM39758.1 - 0.17 12.2 1.8 0.57 10.5 1.8 1.9 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain DUF4164 PF13747.6 GAM39758.1 - 0.76 10.1 8.9 0.25 11.6 4.4 2.6 2 1 1 3 3 2 0 Domain of unknown function (DUF4164) IBR PF01485.21 GAM39758.1 - 0.87 9.9 4.2 2.2 8.6 4.2 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PhoLip_ATPase_C PF16212.5 GAM39759.1 - 1.5e-81 273.9 23.4 1.5e-81 273.9 23.4 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAM39759.1 - 4.4e-22 77.5 0.8 1.4e-21 75.9 0.8 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GAM39759.1 - 2e-10 40.6 0.0 1e-09 38.3 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM39759.1 - 3.8e-09 37.1 5.1 7.5e-05 23.1 1.3 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAM39759.1 - 1.1e-05 25.1 0.0 5.1e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAM39759.1 - 0.072 12.8 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Arylesterase PF01731.20 GAM39761.1 - 1.5e-05 25.1 0.0 4.5e-05 23.6 0.1 1.8 2 0 0 2 2 2 1 Arylesterase SGL PF08450.12 GAM39761.1 - 0.028 14.0 0.0 0.1 12.1 0.0 2.0 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region vATP-synt_E PF01991.18 GAM39763.1 - 1.1e-60 204.5 10.9 1.3e-60 204.3 10.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit CitT PF12431.8 GAM39763.1 - 0.15 12.4 0.2 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator Med3 PF11593.8 GAM39763.1 - 0.18 11.0 4.0 0.31 10.2 4.0 1.4 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4288 PF14119.6 GAM39763.1 - 0.23 11.9 3.8 8.6 6.8 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) Mg_trans_NIPA PF05653.14 GAM39764.1 - 5.4e-14 52.0 10.4 8.3e-07 28.4 0.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 GAM39764.1 - 5.5e-06 26.6 1.5 5.5e-06 26.6 1.5 2.8 2 1 1 3 3 3 1 EamA-like transporter family PUNUT PF16913.5 GAM39764.1 - 0.00018 20.9 0.5 0.00018 20.9 0.5 2.0 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport DUF1206 PF06724.11 GAM39764.1 - 0.02 15.0 5.2 6.6 6.9 0.2 3.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) TMEM61 PF15105.6 GAM39764.1 - 0.094 12.5 0.1 0.29 10.9 0.1 1.8 2 0 0 2 2 2 0 TMEM61 protein family SRF-TF PF00319.18 GAM39765.1 - 3.4e-21 74.4 0.1 5.1e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Enkurin PF13864.6 GAM39765.1 - 0.052 14.0 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 Calmodulin-binding Tetraspanin PF00335.20 GAM39766.1 - 3.4e-07 30.2 7.6 5.3e-07 29.6 7.6 1.4 1 0 0 1 1 1 1 Tetraspanin family DUF716 PF04819.12 GAM39766.1 - 0.06 13.0 5.5 0.2 11.3 5.5 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF716) DUF2556 PF10831.8 GAM39766.1 - 7.6 6.6 9.7 11 6.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2556) Fungal_trans PF04082.18 GAM39767.1 - 1.1e-14 54.1 0.6 2.5e-14 52.9 0.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM39767.1 - 5.4e-09 36.0 14.3 5.4e-09 36.0 14.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF604 PF04646.12 GAM39768.1 - 8.2e-09 35.2 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 GAM39768.1 - 5.2e-05 22.8 0.0 0.00012 21.6 0.0 1.5 1 1 0 1 1 1 1 Fringe-like GDI PF00996.18 GAM39769.1 - 1.2e-26 93.3 0.0 9.8e-26 90.2 0.0 1.9 1 1 0 1 1 1 1 GDP dissociation inhibitor Pro_isomerase PF00160.21 GAM39770.1 - 5.9e-55 185.9 0.0 6.7e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.13 GAM39771.1 - 1.3e-62 212.0 4.5 2.4e-62 211.1 4.5 1.4 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 GAM39771.1 - 5.8e-07 29.3 5.6 6.1e-07 29.2 2.7 2.1 2 0 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Adaptin_binding PF10199.9 GAM39771.1 - 8.8 7.0 14.9 7.6 7.2 6.5 2.4 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 RNase_PH PF01138.21 GAM39772.1 - 1.4e-15 57.9 0.1 1e-14 55.2 0.1 2.2 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 CENP-B_dimeris PF09026.10 GAM39772.1 - 1.5 9.3 5.8 2.5 8.5 2.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 GAM39772.1 - 2.2 8.7 7.6 1.4 9.3 4.2 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NAD_binding_6 PF08030.12 GAM39773.1 - 1.7e-20 73.7 0.0 1.6e-19 70.5 0.0 2.3 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 GAM39773.1 - 1.3e-17 64.1 9.5 1.3e-17 64.1 9.5 2.5 4 0 0 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAM39773.1 - 1.8e-11 44.0 0.0 6e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 GAM39773.1 - 0.00011 22.8 0.0 0.47 11.1 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 GAM39773.1 - 1.6 9.3 12.4 0.12 12.9 1.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Acetyltransf_1 PF00583.25 GAM39774.1 - 0.0011 19.2 0.0 0.026 14.8 0.0 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family RRN3 PF05327.11 GAM39774.1 - 0.22 10.0 3.6 0.28 9.7 3.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.11 GAM39774.1 - 6.1 6.3 14.5 9.4 5.7 14.5 1.2 1 0 0 1 1 1 0 PPP4R2 Sgf11 PF08209.11 GAM39775.1 - 2.1e-13 49.5 0.9 2.1e-13 49.5 0.9 2.0 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) PRA-PH PF01503.17 GAM39775.1 - 0.16 12.4 2.9 0.41 11.1 2.9 1.7 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase GST_C_3 PF14497.6 GAM39776.1 - 1.3e-18 67.0 0.0 2.1e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM39776.1 - 1.3e-07 31.8 0.0 2e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM39776.1 - 0.0007 19.8 0.1 0.0021 18.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM39776.1 - 0.0018 18.7 0.0 0.03 14.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM39776.1 - 0.003 17.5 0.0 0.0087 16.1 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM39776.1 - 0.011 16.1 0.0 0.29 11.5 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 GAM39776.1 - 0.1 13.3 0.0 0.28 11.9 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain zf-C2HC5 PF06221.13 GAM39777.1 - 7.5e-22 77.1 7.8 1.2e-21 76.5 7.8 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type p450 PF00067.22 GAM39778.1 - 3.2e-69 233.8 0.0 5.8e-69 233.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.22 GAM39778.1 - 0.012 15.6 3.1 0.013 15.5 1.4 1.9 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Hexokinase_2 PF03727.16 GAM39779.1 - 8.4e-77 257.8 0.1 1.1e-76 257.4 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 GAM39779.1 - 5.5e-75 251.6 0.0 9e-75 250.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase POP1 PF06978.11 GAM39780.1 - 5.2e-76 255.2 13.9 5.2e-76 255.2 13.9 2.8 3 0 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 DUF1690 PF07956.11 GAM39780.1 - 5.4e-37 127.3 19.8 1.7e-19 70.6 1.3 3.7 3 1 0 3 3 3 2 Protein of Unknown function (DUF1690) POPLD PF08170.12 GAM39780.1 - 2.2e-34 117.6 0.9 8.6e-34 115.8 0.9 2.1 1 0 0 1 1 1 1 POPLD (NUC188) domain Aminotran_1_2 PF00155.21 GAM39780.1 - 6.8e-31 107.7 0.0 1.4e-30 106.7 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II AA_permease PF00324.21 GAM39781.1 - 3.5e-103 345.8 38.0 4e-103 345.6 38.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM39781.1 - 7.3e-25 87.7 41.2 1e-24 87.2 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 GAM39782.1 - 7e-23 81.1 50.7 3.3e-20 72.3 49.7 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 GAM39783.1 - 2.1e-43 148.6 61.0 2.7e-33 115.4 27.5 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM39783.1 - 3e-14 52.8 29.8 4.8e-13 48.8 6.6 3.3 2 1 0 3 3 3 2 Sugar (and other) transporter SelK_SelG PF10961.8 GAM39783.1 - 0.028 15.0 0.0 0.13 12.9 0.0 2.1 1 0 0 1 1 1 0 Selenoprotein SelK_SelG DUF485 PF04341.12 GAM39783.1 - 0.44 10.5 0.1 0.44 10.5 0.1 4.0 3 1 0 3 3 3 0 Protein of unknown function, DUF485 DIT1_PvcA PF05141.12 GAM39784.1 - 7.8e-93 310.9 0.0 1.3e-92 310.2 0.0 1.4 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.28 GAM39784.1 - 1.4e-28 99.7 0.0 2.3e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.15 GAM39784.1 - 4.5e-09 35.5 0.0 4.4e-06 25.6 0.0 2.8 2 1 0 2 2 2 2 Transferase family PP-binding PF00550.25 GAM39784.1 - 1.6e-05 25.1 0.0 3.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Glyco_hydro_11 PF00457.17 GAM39785.1 - 6.4e-49 166.0 17.8 1e-48 165.3 17.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 adh_short PF00106.25 GAM39785.1 - 1.3e-20 73.8 0.0 4.1e-16 59.0 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase Fungal_trans PF04082.18 GAM39785.1 - 5.2e-19 68.3 0.3 9e-19 67.5 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 GAM39785.1 - 1.2e-12 47.9 0.0 1.4e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM39785.1 - 0.00053 20.0 0.1 0.0014 18.6 0.1 1.6 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAM39785.1 - 0.019 14.3 0.0 0.051 12.9 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1190 PF06693.11 GAM39785.1 - 0.15 12.4 2.0 0.36 11.2 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) Peptidase_S64 PF08192.11 GAM39786.1 - 0.00075 18.1 0.5 0.0084 14.7 0.0 2.0 2 0 0 2 2 2 2 Peptidase family S64 Pkinase PF00069.25 GAM39787.1 - 2e-67 227.3 0.0 1.3e-66 224.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 GAM39787.1 - 4.3e-38 129.6 0.2 2.6e-37 127.1 0.1 2.2 2 0 0 2 2 2 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 GAM39787.1 - 1.2e-35 123.1 0.0 8.9e-34 116.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAM39787.1 - 0.00022 20.3 0.0 0.00061 18.8 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 GAM39787.1 - 0.00028 20.9 0.1 0.016 15.2 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAM39787.1 - 0.0013 18.2 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAM39787.1 - 0.0077 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 GAM39787.1 - 0.03 13.9 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 GAM39787.1 - 0.062 12.9 0.1 8.2 6.0 0.0 2.8 2 1 1 3 3 3 0 RIO1 family DUF1348 PF07080.11 GAM39788.1 - 2.5e-38 131.0 7.1 1.1e-37 128.8 7.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1348) Imm27 PF15590.6 GAM39788.1 - 0.11 12.3 4.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 27 Redoxin PF08534.10 GAM39789.1 - 8.3e-36 122.9 0.0 9.5e-36 122.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAM39789.1 - 2.9e-12 46.6 0.0 3.9e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Flavoprotein PF02441.19 GAM39790.1 - 2.2e-44 151.0 0.4 6.4e-44 149.5 0.4 1.7 1 1 0 1 1 1 1 Flavoprotein Knl1_RWD_C PF18210.1 GAM39790.1 - 0.13 12.8 0.2 14 6.3 0.0 2.4 1 1 0 2 2 2 0 Knl1 RWD C-terminal domain Zn_clus PF00172.18 GAM39792.1 - 2.1e-08 34.2 6.8 3.1e-08 33.6 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2461 PF09365.10 GAM39793.1 - 1.3e-63 214.7 0.3 1.8e-63 214.3 0.3 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Presenilin PF01080.17 GAM39793.1 - 3 6.5 7.9 4.6 5.9 7.9 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GAM39793.1 - 4.9 5.3 9.7 7 4.8 9.7 1.3 1 0 0 1 1 1 0 CDC45-like protein TYW3 PF02676.14 GAM39794.1 - 4.7e-77 258.2 0.0 8.1e-77 257.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase TYW3 PGA2 PF07543.12 GAM39794.1 - 9.3 6.2 11.8 3.6 7.6 2.5 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 RRM_1 PF00076.22 GAM39795.1 - 4.2e-05 23.3 0.0 0.0002 21.1 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metal_resist PF13801.6 GAM39795.1 - 0.69 10.1 5.9 1.7 8.8 5.9 1.6 1 0 0 1 1 1 0 Heavy-metal resistance CREPT PF16566.5 GAM39795.1 - 0.86 9.8 5.2 1.9 8.6 5.2 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour ARPC4 PF05856.12 GAM39796.1 - 4.1e-78 260.8 3.7 4.6e-78 260.6 3.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.29 GAM39797.1 - 5.4e-51 173.6 0.0 6.9e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 GAM39797.1 - 8.4e-11 41.5 0.0 2.6e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family UCH_1 PF13423.6 GAM39797.1 - 1.5e-10 41.2 8.3 2e-09 37.5 8.3 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 GAM39797.1 - 0.058 12.9 0.0 17 4.7 0.0 3.0 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase 4HBT PF03061.22 GAM39798.1 - 8.3e-08 32.5 0.2 1.7e-07 31.5 0.2 1.6 1 0 0 1 1 1 1 Thioesterase superfamily TRI12 PF06609.13 GAM39799.1 - 2.1e-37 128.9 30.1 2.1e-37 128.9 30.1 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 GAM39799.1 - 1.1e-15 57.5 49.0 1.1e-15 57.5 49.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM39799.1 - 3.6e-07 29.4 13.8 3.6e-07 29.4 13.8 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter Cation_ATPase_C PF00689.21 GAM39799.1 - 0.011 15.4 3.2 0.011 15.4 3.2 2.6 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus WD40 PF00400.32 GAM39800.1 - 4.9e-09 36.7 19.2 0.0039 18.0 0.1 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 GAM39800.1 - 3.8e-06 26.4 18.1 3.8e-06 26.4 18.1 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type RWD PF05773.22 GAM39800.1 - 0.00073 19.8 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 GAM39800.1 - 2.3 8.5 12.1 0.9 9.8 7.6 2.5 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain zf-RING_14 PF17978.1 GAM39800.1 - 5.3 7.5 7.9 11 6.5 7.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain UQ_con PF00179.26 GAM39801.1 - 1.5e-47 160.8 0.0 1.7e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM39801.1 - 0.00024 20.8 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 GAM39801.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 GAM39801.1 - 0.14 12.5 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain Ribosomal_L24e PF01246.20 GAM39802.1 - 2e-28 98.4 0.1 5.6e-28 97.0 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e Acetyltransf_1 PF00583.25 GAM39803.1 - 3.2e-10 40.2 0.1 4.5e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM39803.1 - 3.2e-08 33.6 0.0 5.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM39803.1 - 2.1e-07 31.2 0.4 3.5e-07 30.5 0.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Isochorismatase PF00857.20 GAM39804.1 - 2e-24 86.7 0.0 2.4e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF2584 PF10763.9 GAM39804.1 - 0.17 12.1 1.1 3.8 7.7 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2584) MFS_1 PF07690.16 GAM39805.1 - 7.4e-47 160.0 20.5 1.4e-42 145.9 15.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 GAM39805.1 - 0.05 12.5 6.1 0.75 8.7 0.1 2.6 3 0 0 3 3 3 0 Sugar-tranasporters, 12 TM DUF2516 PF10724.9 GAM39805.1 - 1.3 9.3 5.4 2.1 8.7 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2516) Ring_hydroxyl_A PF00848.19 GAM39806.1 - 1.8e-14 54.2 2.2 5.2e-10 39.6 0.0 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 GAM39806.1 - 9e-14 51.2 0.0 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain MFS_1 PF07690.16 GAM39807.1 - 1.4e-13 50.6 29.5 2.5e-13 49.7 29.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM39807.1 - 1.4e-11 44.0 15.8 2.2e-10 40.0 7.3 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter Aminotran_1_2 PF00155.21 GAM39808.1 - 4.8e-71 239.8 0.0 5.5e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Chorismate_bind PF00425.18 GAM39809.1 - 1e-63 215.3 0.0 1.7e-63 214.6 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 GAM39809.1 - 1.9e-24 86.5 0.0 7.5e-24 84.6 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 GAM39809.1 - 7.3e-13 48.9 0.0 2.2e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 GAM39809.1 - 0.12 12.1 1.9 2 8.1 0.0 2.8 3 0 0 3 3 3 0 Peptidase C26 DUF3684 PF12449.8 GAM39810.1 - 0 1415.0 0.4 0 1414.7 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 GAM39810.1 - 0.00014 21.7 0.0 0.0004 20.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pep1_7 PF17232.2 GAM39810.1 - 0.013 15.9 1.1 1 9.9 0.5 2.9 2 0 0 2 2 2 0 Elicitor peptide 1-7 WLM PF08325.10 GAM39810.1 - 1.5 8.9 5.2 1.4 8.9 0.9 2.3 2 0 0 2 2 2 0 WLM domain TRAPPC9-Trs120 PF08626.11 GAM39811.1 - 0 1493.7 0.0 0 1493.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit fn3_5 PF06280.12 GAM39811.1 - 0.12 13.1 0.1 0.61 10.8 0.0 2.4 2 0 0 2 2 2 0 Fn3-like domain PAC3 PF10178.9 GAM39812.1 - 4.4e-06 26.7 0.0 7.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 HA2 PF04408.23 GAM39813.1 - 2.6e-27 95.2 0.0 2.6e-27 95.2 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAM39813.1 - 1.1e-12 48.3 0.0 7.1e-12 45.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 GAM39813.1 - 7.2e-10 39.1 0.0 1.5e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 GAM39813.1 - 1.2e-09 38.2 0.1 3.3e-08 33.5 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 GAM39813.1 - 7.9e-05 22.7 2.6 1.3 9.0 0.0 3.4 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAM39813.1 - 0.004 17.4 0.1 0.028 14.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 GAM39813.1 - 0.0081 16.7 0.0 0.0081 16.7 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 GAM39813.1 - 0.02 14.6 0.0 0.053 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAM39813.1 - 0.032 14.6 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAM39813.1 - 0.036 13.1 0.0 0.09 11.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 GAM39813.1 - 0.04 13.3 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 GAM39813.1 - 0.06 13.1 0.7 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain cwf21 PF08312.12 GAM39814.1 - 3.4e-17 62.3 18.5 1.1e-16 60.7 18.5 1.9 1 0 0 1 1 1 1 cwf21 domain Tox-GHH PF15636.6 GAM39814.1 - 2.2 8.3 10.9 3 7.9 2.6 2.5 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Neur_chan_memb PF02932.16 GAM39814.1 - 8.1 6.4 7.1 10 6.1 7.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PUF PF00806.19 GAM39815.1 - 3.7e-63 205.8 14.9 4.3e-10 38.7 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat CPL PF08144.11 GAM39815.1 - 0.00034 21.0 3.2 2.8 8.3 0.7 4.6 1 1 2 5 5 5 2 CPL (NUC119) domain sCache_2 PF17200.4 GAM39815.1 - 0.11 12.4 1.4 78 3.1 0.0 4.5 5 0 0 5 5 5 0 Single Cache domain 2 LOB PF03195.14 GAM39815.1 - 0.15 12.7 0.9 4.7 7.9 0.2 3.4 2 1 1 4 4 4 0 Lateral organ boundaries (LOB) domain DUF234 PF03008.14 GAM39815.1 - 0.66 10.5 4.0 0.82 10.2 0.1 2.8 4 0 0 4 4 4 0 Archaea bacterial proteins of unknown function EphA2_TM PF14575.6 GAM39816.1 - 0.18 12.7 0.2 0.25 12.2 0.2 1.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LST1 PF05083.13 GAM39816.1 - 0.33 11.3 1.9 0.53 10.6 1.8 1.4 1 1 0 1 1 1 0 LST-1 protein Phosphodiest PF01663.22 GAM39817.1 - 3.2e-14 53.3 0.4 5.8e-14 52.5 0.4 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 GAM39817.1 - 4.6e-07 29.5 0.6 9.2e-07 28.5 0.6 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 GAM39817.1 - 8.7e-07 28.6 0.0 3.5e-06 26.6 0.0 1.7 1 1 0 2 2 2 1 Sulfatase Man-6-P_recep PF02157.15 GAM39817.1 - 0.071 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate receptor MCM6_C PF18263.1 GAM39817.1 - 0.2 11.9 0.0 0.38 11.0 0.0 1.4 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain DUF3384 PF11864.8 GAM39818.1 - 9.3e-94 315.0 6.7 9.3e-94 315.0 6.7 2.0 2 1 1 3 3 3 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 GAM39818.1 - 1.3e-50 171.5 0.0 3.6e-50 170.1 0.0 1.8 2 0 0 2 2 2 1 Rap/ran-GAP Tuberin PF03542.16 GAM39818.1 - 1.1e-33 116.8 0.1 4e-29 101.8 0.0 3.6 4 0 0 4 4 4 3 Tuberin RTP1_C1 PF10363.9 GAM39818.1 - 0.008 16.3 1.1 0.3 11.3 0.0 3.2 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Bystin PF05291.11 GAM39818.1 - 0.0091 15.3 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 Bystin CAS_CSE1 PF03378.15 GAM39819.1 - 2.1e-198 659.3 0.5 2.1e-198 659.3 0.5 1.8 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 GAM39819.1 - 4.7e-134 446.9 2.6 2.5e-88 296.4 0.1 2.3 1 1 1 2 2 2 2 Cse1 IBN_N PF03810.19 GAM39819.1 - 2.5e-16 59.3 0.0 1.1e-15 57.2 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 GAM39819.1 - 0.043 13.9 1.8 4 7.5 0.0 4.2 6 0 0 6 6 6 0 Exportin 1-like protein DUF1529 PF07485.11 GAM39819.1 - 0.051 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) V-ATPase_H_N PF03224.14 GAM39819.1 - 0.066 12.5 0.1 0.37 10.0 0.0 2.1 2 0 0 2 2 2 0 V-ATPase subunit H RF-1 PF00472.20 GAM39820.1 - 1.5e-23 82.9 7.3 1.5e-23 82.9 7.3 1.3 1 1 0 1 1 1 1 RF-1 domain SPT_ssu-like PF11779.8 GAM39821.1 - 2.7e-25 87.8 2.9 3.7e-25 87.3 2.9 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Pet100 PF09803.9 GAM39822.1 - 1.3e-18 67.2 0.4 1.9e-18 66.8 0.4 1.3 1 0 0 1 1 1 1 Pet100 DUF5621 PF18532.1 GAM39822.1 - 0.029 14.3 0.0 0.038 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5621) TMEM247 PF15444.6 GAM39822.1 - 0.041 13.9 1.3 0.048 13.7 1.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 TMIE PF16038.5 GAM39822.1 - 0.12 12.2 1.9 0.17 11.8 1.9 1.2 1 0 0 1 1 1 0 TMIE protein Abhydrolase_1 PF00561.20 GAM39824.1 - 4.6e-14 52.7 0.1 8.3e-14 51.8 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM39824.1 - 5.9e-10 40.1 0.0 9.6e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM39824.1 - 1.6e-06 27.5 0.0 2.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAM39824.1 - 0.023 14.4 0.0 0.17 11.6 0.0 2.2 1 1 1 2 2 2 0 PGAP1-like protein Abhydrolase_5 PF12695.7 GAM39824.1 - 0.026 14.3 0.0 0.2 11.4 0.0 2.3 2 1 1 3 3 3 0 Alpha/beta hydrolase family TPR_10 PF13374.6 GAM39825.1 - 8.2e-46 152.7 12.0 2.5e-09 36.7 0.0 8.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 GAM39825.1 - 2.4e-43 146.3 9.4 1.7e-14 53.8 0.1 5.0 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM39825.1 - 1.6e-08 34.3 3.7 0.0052 16.2 0.5 3.2 1 1 2 3 3 3 3 MalT-like TPR region NB-ARC PF00931.22 GAM39825.1 - 2.5e-07 30.2 0.0 3.6e-06 26.4 0.0 2.4 2 1 0 2 2 2 1 NB-ARC domain TPR_2 PF07719.17 GAM39825.1 - 3.4e-07 29.9 5.0 1 9.6 0.1 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM39825.1 - 7.3e-07 28.8 2.3 0.47 10.6 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM39825.1 - 1.2e-06 28.2 2.2 9.3 6.8 0.0 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM39825.1 - 4.3e-05 24.0 6.8 0.43 11.5 0.1 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat NACHT PF05729.12 GAM39825.1 - 5.8e-05 23.1 0.0 0.00018 21.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 GAM39825.1 - 0.00041 19.8 0.1 0.001 18.5 0.1 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 GAM39825.1 - 0.0014 18.8 1.3 0.074 13.2 0.2 2.9 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_1 PF00515.28 GAM39825.1 - 0.0026 17.5 1.7 0.91 9.5 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM39825.1 - 0.0032 18.1 7.6 1.6 9.5 0.0 5.2 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM39825.1 - 0.02 15.4 1.0 3 8.4 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF1640 PF07798.11 GAM39826.1 - 7.7e-40 136.8 4.7 1.3e-39 136.1 4.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Vps51 PF08700.11 GAM39827.1 - 1.2e-13 50.9 0.1 8.3e-13 48.2 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 D123 PF07065.14 GAM39828.1 - 7.8e-115 383.2 0.1 7.8e-115 383.2 0.1 1.3 2 0 0 2 2 2 1 D123 ECH_1 PF00378.20 GAM39829.1 - 3.9e-21 75.5 0.0 5.6e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM39829.1 - 1e-11 45.0 0.0 1.2e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Transferase PF02458.15 GAM39830.1 - 3.8e-24 85.1 0.0 6.8e-22 77.7 0.0 2.1 2 0 0 2 2 2 2 Transferase family Condensation PF00668.20 GAM39830.1 - 0.011 14.5 0.1 0.14 10.8 0.0 2.1 2 0 0 2 2 2 0 Condensation domain ABC_tran_Xtn PF12848.7 GAM39831.1 - 0.0043 17.1 1.0 0.018 15.1 0.2 1.9 1 1 1 2 2 2 1 ABC transporter DUF4635 PF15466.6 GAM39831.1 - 0.042 13.4 0.3 0.048 13.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) MMS22L_C PF14911.6 GAM39831.1 - 0.047 12.8 0.2 0.053 12.6 0.2 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal DUF4988 PF16378.5 GAM39831.1 - 0.087 12.5 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF1515 PF07439.11 GAM39831.1 - 0.093 12.8 0.2 0.095 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) LST1 PF05083.13 GAM39831.1 - 0.12 12.6 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 LST-1 protein DivIC PF04977.15 GAM39831.1 - 0.19 11.5 1.6 0.26 11.1 1.3 1.4 1 1 0 1 1 1 0 Septum formation initiator MFS_1 PF07690.16 GAM39832.1 - 7.9e-37 127.0 64.4 2e-35 122.3 47.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HEAT_2 PF13646.6 GAM39834.1 - 9.6e-10 38.7 6.2 0.32 11.4 0.0 7.8 6 2 2 9 9 9 2 HEAT repeats HEAT PF02985.22 GAM39834.1 - 2.9e-05 24.0 17.8 7 7.2 0.0 9.7 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.6 GAM39834.1 - 0.0081 16.7 7.1 32 5.2 0.1 7.9 8 1 0 8 8 8 1 HEAT-like repeat Transcrip_reg PF01709.20 GAM39835.1 - 1.9e-70 237.0 1.3 2.2e-70 236.8 1.3 1.0 1 0 0 1 1 1 1 Transcriptional regulator ACT_4 PF13291.6 GAM39835.1 - 0.05 14.2 0.1 12 6.6 0.0 2.4 2 0 0 2 2 2 0 ACT domain CLPTM1 PF05602.12 GAM39836.1 - 5.1e-164 546.4 0.8 6.6e-164 546.0 0.8 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) CENP-I PF07778.11 GAM39836.1 - 5.1e-39 134.4 0.0 2.2e-38 132.3 0.0 1.8 1 1 0 1 1 1 1 Mis6 adh_short PF00106.25 GAM39837.1 - 2e-21 76.4 0.0 5.2e-21 75.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM39837.1 - 9.4e-16 58.1 0.0 1.4e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Rap1-DNA-bind PF09197.10 GAM39837.1 - 0.087 13.4 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Rap1, DNA-binding Caprin-1_C PF12287.8 GAM39837.1 - 0.11 12.7 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term DUF1776 PF08643.10 GAM39837.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ASXH PF13919.6 GAM39838.1 - 1.5e-37 128.7 1.6 3.2e-37 127.7 1.6 1.6 1 0 0 1 1 1 1 Asx homology domain Longin PF13774.6 GAM39839.1 - 4.6e-27 93.9 0.6 7.6e-27 93.2 0.6 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 GAM39839.1 - 7.3e-14 51.3 0.0 1.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin SLM4 PF16818.5 GAM39839.1 - 0.0031 17.5 0.4 0.24 11.3 0.0 2.1 1 1 1 2 2 2 2 Protein SLM4 DUF3958 PF13125.6 GAM39839.1 - 0.075 13.2 0.5 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Elong_Iki1 PF10483.9 GAM39840.1 - 2.9e-104 348.8 0.0 3.3e-104 348.6 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 PIG-L PF02585.17 GAM39841.1 - 0.00032 21.3 0.0 0.00052 20.6 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Gly_transf_sug PF04488.15 GAM39842.1 - 4.7e-10 40.0 0.0 9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 GAM39842.1 - 0.24 10.7 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Glyco_hydro_63 PF03200.16 GAM39843.1 - 2e-172 574.4 7.4 1.6e-171 571.4 7.4 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 GAM39843.1 - 9e-89 297.4 0.0 2.6e-88 295.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain DAO PF01266.24 GAM39843.1 - 3.5e-64 217.6 0.6 5.5e-64 217.0 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase SNRNP27 PF08648.12 GAM39843.1 - 2.7e-17 62.6 2.5 6.7e-17 61.3 2.5 1.7 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Trehalase PF01204.18 GAM39843.1 - 0.00036 19.5 0.4 0.00073 18.5 0.4 1.4 1 0 0 1 1 1 1 Trehalase NAD_binding_8 PF13450.6 GAM39843.1 - 0.00078 19.6 0.2 0.0025 18.0 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAM39843.1 - 0.0034 16.3 1.2 4.9 5.9 0.0 3.1 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 GAM39843.1 - 0.005 16.1 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase RabGAP-TBC PF00566.18 GAM39844.1 - 1.6e-39 135.8 0.2 3.3e-39 134.8 0.2 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 GAM39844.1 - 5.5e-08 32.5 0.0 1.5e-06 27.8 0.0 2.4 1 1 0 1 1 1 1 Rab-binding domain (RBD) Peptidase_M50B PF13398.6 GAM39845.1 - 7.6e-59 198.7 22.7 9.6e-59 198.4 22.7 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 GAM39845.1 - 0.009 15.3 0.3 0.021 14.1 0.3 1.5 1 0 0 1 1 1 1 Peptidase family M50 Peptidase_M41 PF01434.18 GAM39845.1 - 0.24 11.2 0.2 0.36 10.7 0.2 1.2 1 0 0 1 1 1 0 Peptidase family M41 DUF3619 PF12279.8 GAM39845.1 - 1.3 9.4 3.0 4.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) Patched PF02460.18 GAM39845.1 - 4.1 5.3 9.1 1.8 6.5 6.7 1.6 1 1 1 2 2 2 0 Patched family YlaC PF10777.9 GAM39845.1 - 6 6.7 5.8 0.5 10.2 0.5 1.9 2 0 0 2 2 2 0 Inner membrane protein YlaC CRT10 PF08728.10 GAM39846.1 - 1.1e-19 70.1 0.0 2.7e-13 49.0 0.0 2.4 2 0 0 2 2 2 2 CRT10 H_lectin PF09458.10 GAM39846.1 - 0.11 12.7 0.8 2.8 8.2 0.0 3.3 4 0 0 4 4 4 0 H-type lectin domain MMtag PF10159.9 GAM39847.1 - 3.3e-35 120.2 1.9 5.8e-35 119.4 1.9 1.4 1 0 0 1 1 1 1 Multiple myeloma tumor-associated AadA_C PF18280.1 GAM39847.1 - 0.038 14.1 0.1 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Aminoglycoside adenyltransferase C-terminal domain PhoLip_ATPase_C PF16212.5 GAM39848.1 - 3.4e-49 167.9 8.4 3.4e-49 167.9 8.4 1.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAM39848.1 - 4.3e-16 58.3 1.2 8.7e-16 57.4 1.2 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 GAM39848.1 - 4.5e-14 53.2 1.9 1.5e-08 35.2 0.6 2.9 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM39848.1 - 3e-08 33.7 0.0 1.8e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAM39848.1 - 0.0029 17.4 0.0 0.0067 16.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAM39848.1 - 0.047 13.2 0.1 0.047 13.2 0.1 2.8 3 0 0 3 3 3 0 E1-E2 ATPase Sec16_C PF12931.7 GAM39849.1 - 5.7e-112 374.3 0.0 7.6e-112 373.9 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.7 GAM39849.1 - 2.7e-50 171.8 25.4 2.7e-50 171.8 25.4 4.8 2 1 1 3 3 3 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.7 GAM39849.1 - 2.5e-31 108.7 0.0 5.6e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region DUF3499 PF12005.8 GAM39849.1 - 0.13 12.9 0.8 0.44 11.2 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) Sugar_tr PF00083.24 GAM39850.1 - 1.1e-83 281.6 19.9 1.4e-83 281.3 19.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM39850.1 - 2.7e-28 98.9 23.9 2.7e-28 98.9 23.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM39850.1 - 4.9e-07 28.5 1.9 9.3e-07 27.6 1.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mso1_Sec1_bdg PF14475.6 GAM39851.1 - 2.8e-15 55.6 0.1 5.2e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.17 GAM39852.1 - 1.7e-40 138.3 1.2 2.9e-40 137.6 1.2 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 GAM39852.1 - 8.7e-30 103.3 14.2 8.7e-30 103.3 14.2 2.3 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 GAM39852.1 - 5.4e-07 29.3 12.6 6.9e-07 29.0 12.6 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 GAM39852.1 - 0.11 10.6 21.9 0.15 10.3 21.9 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GAM39852.1 - 3.6 6.1 25.5 4.7 5.7 25.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-C2H2_4 PF13894.6 GAM39853.1 - 7e-08 32.7 30.0 0.02 15.7 0.1 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 GAM39853.1 - 0.0023 18.3 7.3 0.018 15.5 0.2 3.8 3 0 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2 PF00096.26 GAM39853.1 - 0.0024 18.2 27.8 0.035 14.6 0.1 6.2 6 0 0 6 6 6 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 GAM39853.1 - 0.022 14.8 13.4 0.12 12.4 0.0 3.9 5 0 0 5 5 5 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 GAM39853.1 - 0.049 13.3 0.2 0.049 13.3 0.2 3.7 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 GAM39853.1 - 0.086 13.2 16.8 0.064 13.6 4.3 3.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) GSHPx PF00255.19 GAM39853.1 - 0.12 11.9 0.2 0.3 10.7 0.2 1.7 1 0 0 1 1 1 0 Glutathione peroxidase zf-C2H2_jaz PF12171.8 GAM39853.1 - 0.12 12.7 0.2 0.12 12.7 0.2 4.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 GAM39853.1 - 0.91 10.2 12.7 13 6.5 0.3 4.1 2 1 2 4 4 4 0 FOXP coiled-coil domain Stc1 PF12898.7 GAM39853.1 - 1.7 9.3 12.2 4.2 8.0 2.7 3.4 3 1 0 3 3 3 0 Stc1 domain zf-C2HE PF16278.5 GAM39853.1 - 2.9 8.4 13.4 1.4 9.4 2.5 3.4 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-XS PF03470.14 GAM39853.1 - 5.7 7.3 6.4 2.9 8.2 1.1 2.7 3 0 0 3 3 3 0 XS zinc finger domain TF_Zn_Ribbon PF08271.12 GAM39853.1 - 6.8 6.3 7.5 25 4.5 0.1 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding DUF3402 PF11882.8 GAM39854.1 - 3.9e-168 560.3 0.0 9.5e-129 430.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 GAM39854.1 - 3.7e-90 302.0 0.0 5.2e-90 301.5 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein ODV-E18 PF10717.9 GAM39854.1 - 0.03 14.2 0.0 5.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF3720 PF12517.8 GAM39854.1 - 2.8 8.9 8.5 0.13 13.2 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) PAP2 PF01569.21 GAM39855.1 - 5.9e-13 48.8 4.1 5.9e-13 48.8 4.1 2.2 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 GAM39855.1 - 0.1 12.8 0.6 1.6 8.9 0.4 2.3 1 1 0 1 1 1 0 Divergent PAP2 family IBR PF01485.21 GAM39856.1 - 2.5e-20 72.5 38.1 4.3e-15 55.7 3.6 4.2 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 GAM39856.1 - 1.4e-16 60.8 0.0 2.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 RWD domain GAS2 PF02187.17 GAM39857.1 - 2.6e-06 27.4 0.2 6e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain FAD_binding_3 PF01494.19 GAM39858.1 - 2.6e-10 40.1 0.0 0.0011 18.3 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.6 GAM39858.1 - 0.0024 17.2 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM39858.1 - 0.0032 17.7 0.0 0.0077 16.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM39858.1 - 0.011 15.4 0.4 0.55 9.8 0.1 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 GAM39858.1 - 0.051 12.8 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 GAM39858.1 - 0.062 12.5 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Zn_dep_PLPC PF00882.18 GAM39858.1 - 0.069 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Zinc dependent phospholipase C SE PF08491.10 GAM39858.1 - 0.086 11.9 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Lycopene_cycl PF05834.12 GAM39858.1 - 0.094 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Hus1 PF04005.12 GAM39859.1 - 1.3e-83 280.5 0.0 2e-83 279.9 0.0 1.3 1 0 0 1 1 1 1 Hus1-like protein Hexokinase_1 PF00349.21 GAM39859.1 - 7.2e-65 218.6 0.0 1.3e-64 217.8 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 GAM39859.1 - 6.3e-49 166.6 0.0 1.2e-48 165.7 0.0 1.4 1 0 0 1 1 1 1 Hexokinase TPR_12 PF13424.6 GAM39859.1 - 2e-21 76.1 11.3 6.8e-09 35.9 0.4 5.7 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAM39859.1 - 1.4e-15 56.6 6.3 5.2e-05 23.0 0.0 5.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM39859.1 - 4.4e-07 29.6 9.4 0.22 11.8 0.2 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM39859.1 - 5.6e-07 29.2 9.8 0.024 14.7 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM39859.1 - 6e-07 29.1 9.8 0.6 10.3 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM39859.1 - 3e-06 27.6 5.2 2.1 9.4 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM39859.1 - 0.00021 21.0 4.8 0.64 9.9 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM39859.1 - 0.0098 15.3 0.2 0.039 13.3 0.3 1.8 1 1 0 1 1 1 1 MalT-like TPR region TPR_19 PF14559.6 GAM39859.1 - 0.018 15.6 3.2 3.4 8.2 0.3 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat zf-MYND PF01753.18 GAM39859.1 - 0.018 15.1 11.9 0.034 14.2 11.9 1.5 1 0 0 1 1 1 0 MYND finger TPR_16 PF13432.6 GAM39859.1 - 0.92 10.2 4.1 20 5.9 0.0 3.8 3 2 1 4 4 4 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 GAM39860.1 - 3.9e-15 57.1 0.0 5.6e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM39860.1 - 1e-12 48.3 0.0 4.3e-11 43.0 0.0 2.5 3 0 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM39860.1 - 2.7e-07 30.1 0.0 4.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAM39860.1 - 0.00058 20.0 0.6 0.0021 18.2 0.2 2.4 2 1 0 2 2 2 1 Thioesterase domain Ser_hydrolase PF06821.13 GAM39860.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase Ring_hydroxyl_A PF00848.19 GAM39861.1 - 2.1e-20 73.6 2.7 4e-09 36.8 1.1 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) 2-Hacid_dh_C PF02826.19 GAM39862.1 - 1.5e-48 164.5 0.6 2.2e-48 164.0 0.6 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAM39862.1 - 2.3e-08 33.8 0.0 5.8e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAM39862.1 - 0.001 19.3 0.1 0.0016 18.6 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HTH_1 PF00126.27 GAM39862.1 - 0.05 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family DHDPS PF00701.22 GAM39863.1 - 7.2e-41 139.8 0.0 9.1e-41 139.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Zn_clus PF00172.18 GAM39864.1 - 1e-08 35.1 8.5 1.7e-08 34.4 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 GAM39865.1 - 1.5e-48 165.5 0.0 7.1e-48 163.3 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Amino_oxidase PF01593.24 GAM39866.1 - 2e-41 142.8 0.1 1.6e-40 139.7 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM39866.1 - 4.1e-06 26.9 0.0 1.1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM39866.1 - 0.037 13.2 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAM39866.1 - 0.087 12.1 0.4 0.18 11.0 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain Epimerase PF01370.21 GAM39867.1 - 4.3e-20 72.2 0.0 5.6e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM39867.1 - 3.5e-12 45.9 0.0 4.7e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM39867.1 - 4.3e-11 42.8 0.0 6.1e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GAM39867.1 - 1.4e-09 37.5 0.0 2.9e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 GAM39867.1 - 2.6e-09 36.6 0.0 3.9e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Ldh_1_N PF00056.23 GAM39867.1 - 0.0028 17.8 0.0 0.0055 16.8 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 GAM39867.1 - 0.0043 17.0 0.0 0.0075 16.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 GAM39867.1 - 0.0055 16.2 0.0 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase 17kDa_Anti_2 PF16998.5 GAM39867.1 - 0.036 14.0 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 17 kDa outer membrane surface antigen Polysacc_synt_2 PF02719.15 GAM39867.1 - 0.04 13.0 0.0 0.079 12.1 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 GAM39867.1 - 0.084 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FMN_dh PF01070.18 GAM39868.1 - 2.1e-114 382.2 0.0 2.6e-114 381.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 GAM39868.1 - 1.8e-21 76.1 0.1 3.2e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 GAM39868.1 - 0.00014 21.2 0.0 0.00025 20.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 GAM39868.1 - 0.00092 18.3 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 GAM39868.1 - 0.01 15.2 0.1 0.48 9.7 0.0 2.4 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 GAM39868.1 - 0.054 12.9 0.0 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.21 GAM39868.1 - 0.054 12.7 0.2 0.33 10.1 0.0 2.2 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase Bac_luciferase PF00296.20 GAM39869.1 - 3e-70 237.2 0.1 3.4e-70 237.0 0.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase ABC_tran PF00005.27 GAM39870.1 - 5.4e-26 91.7 0.2 8.8e-26 91.0 0.2 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 GAM39870.1 - 6.9e-25 87.7 26.0 1.1e-24 87.1 26.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 GAM39870.1 - 8.3e-06 25.8 0.1 6.4e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 GAM39870.1 - 8.6e-06 26.2 0.0 1.4e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 GAM39870.1 - 5.2e-05 23.2 0.1 0.25 11.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 GAM39870.1 - 0.00027 21.4 0.2 0.0024 18.3 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GAM39870.1 - 0.0024 17.5 0.0 0.0052 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAM39870.1 - 0.0035 17.6 0.0 0.0098 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 GAM39870.1 - 0.0039 16.7 0.1 0.046 13.2 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 GAM39870.1 - 0.0052 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 GAM39870.1 - 0.0062 16.5 0.0 0.019 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 GAM39870.1 - 0.0063 16.8 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.6 GAM39870.1 - 0.011 14.5 0.4 0.029 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAM39870.1 - 0.011 16.3 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 GAM39870.1 - 0.018 15.3 0.0 5.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 GAM39870.1 - 0.073 13.2 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAM39870.1 - 0.08 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 GAM39870.1 - 0.081 13.0 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 GAM39870.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 GAM39870.1 - 0.11 11.7 0.0 0.32 10.1 0.0 1.7 1 1 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 GAM39870.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAM39870.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAM39870.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 GAM39870.1 - 0.21 11.5 0.2 0.53 10.2 0.1 1.7 2 0 0 2 2 1 0 NTPase Glyco_hydro_32N PF00251.20 GAM39871.1 - 3.2e-87 292.9 9.2 9.2e-72 242.2 3.8 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 GAM39871.1 - 3e-31 108.6 0.0 5.8e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal CHB_HEX_C PF03174.13 GAM39871.1 - 0.12 12.3 0.1 0.35 10.9 0.1 1.7 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain Sugar_tr PF00083.24 GAM39872.1 - 3.8e-17 62.3 2.4 4.4e-17 62.1 2.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF261 PF03196.13 GAM39872.1 - 0.054 13.6 0.4 0.079 13.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF261 MFS_1 PF07690.16 GAM39873.1 - 2.6e-45 154.9 34.5 1.1e-38 133.1 8.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM39873.1 - 2.4e-11 43.2 15.8 3.4e-11 42.7 5.1 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 GAM39873.1 - 2.5e-05 23.7 10.7 4.6e-05 22.9 1.9 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 GAM39873.1 - 6e-05 22.1 3.4 6e-05 22.1 3.4 2.6 1 1 1 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 GAM39873.1 - 0.0035 15.9 11.4 0.036 12.6 0.4 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein TRI12 PF06609.13 GAM39873.1 - 0.0045 15.5 0.4 0.0072 14.8 0.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 GAM39873.1 - 0.66 8.1 3.8 0.63 8.2 0.9 2.1 2 0 0 2 2 2 0 BT1 family DAO PF01266.24 GAM39874.1 - 3.1e-35 122.4 0.0 4.9e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM39874.1 - 4.2e-06 26.9 0.0 2.2e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM39874.1 - 0.00016 20.9 0.4 0.0023 17.1 0.2 2.6 2 1 0 2 2 2 1 FAD binding domain ThiF PF00899.21 GAM39874.1 - 0.00027 20.4 0.0 0.00074 18.9 0.0 1.7 2 0 0 2 2 2 1 ThiF family Pyr_redox_2 PF07992.14 GAM39874.1 - 0.00042 19.6 0.0 0.053 12.7 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAM39874.1 - 0.012 14.9 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 GAM39874.1 - 0.019 14.0 0.0 0.37 9.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 GAM39874.1 - 0.021 15.4 0.0 0.046 14.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM39874.1 - 0.077 11.8 0.2 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 GAM39874.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM39874.1 - 0.13 12.3 0.4 5 7.1 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 GAM39874.1 - 0.17 12.3 0.0 0.66 10.4 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding LIP PF03583.14 GAM39875.1 - 1.3e-55 188.8 0.0 1.7e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Cutinase PF01083.22 GAM39875.1 - 0.008 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Cutinase Peptidase_S9 PF00326.21 GAM39875.1 - 0.02 14.4 0.0 1 8.8 0.1 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family CutC PF03932.14 GAM39877.1 - 1.2e-44 152.2 0.4 4.6e-41 140.5 0.4 3.8 1 1 0 1 1 1 1 CutC family QRPTase_C PF01729.19 GAM39877.1 - 0.032 14.0 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Med11 PF10280.9 GAM39877.1 - 0.043 14.3 0.1 0.1 13.0 0.1 1.8 1 1 0 1 1 1 0 Mediator complex protein Catalase PF00199.19 GAM39878.1 - 8.9e-174 578.1 0.1 1.1e-173 577.7 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 GAM39878.1 - 1.5e-16 60.4 0.2 4.5e-16 58.8 0.2 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 GAM39878.1 - 6.2e-06 26.1 0.0 3.8e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 GAM39878.1 - 7.8e-05 22.4 0.1 0.00014 21.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Metallophos PF00149.28 GAM39879.1 - 2.1e-15 57.8 0.1 2.8e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM39879.1 - 2.1e-11 44.3 0.2 8.2e-10 39.1 0.2 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Transp_inhibit PF18791.1 GAM39879.1 - 0.019 14.5 0.1 0.019 14.5 0.1 1.9 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain Glycos_transf_1 PF00534.20 GAM39879.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF1857 PF08982.11 GAM39880.1 - 5.4e-38 130.1 0.1 6.1e-38 130.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) FMN_red PF03358.15 GAM39881.1 - 4.3e-18 65.5 0.0 1.5e-17 63.8 0.0 1.8 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAM39881.1 - 0.045 13.5 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin-like fold NAD_binding_4 PF07993.12 GAM39882.1 - 4.8e-30 104.6 0.0 7.5e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAM39882.1 - 1.2e-21 76.8 0.0 1.9e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAM39882.1 - 1.4e-07 31.2 0.0 2.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAM39882.1 - 4.5e-06 26.9 0.1 1.2e-05 25.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 GAM39882.1 - 0.0062 16.0 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase T5orf172 PF10544.9 GAM39884.1 - 2.8e-18 66.3 0.6 2.8e-18 66.3 0.6 2.0 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 GAM39884.1 - 2.2e-13 50.7 1.4 6.1e-13 49.3 0.3 2.3 3 0 0 3 3 3 1 Meiotically up-regulated gene 113 APH PF01636.23 GAM39885.1 - 2.1e-13 50.7 1.1 2.1e-13 50.7 1.1 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Aldedh PF00171.22 GAM39886.1 - 1.3e-121 406.4 0.0 1.6e-121 406.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.19 GAM39886.1 - 0.15 12.1 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Clostridium_P47 PF06597.11 GAM39887.1 - 0.018 13.8 5.4 0.019 13.7 5.4 1.0 1 0 0 1 1 1 0 Clostridium P-47 protein AmpE PF17113.5 GAM39887.1 - 0.061 12.7 0.6 0.06 12.7 0.6 1.0 1 0 0 1 1 1 0 Regulatory signalling modulator protein AmpE DUF5316 PF17247.2 GAM39887.1 - 0.19 11.8 0.2 0.19 11.8 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5316) Mt_ATP-synt_D PF05873.12 GAM39889.1 - 2.5e-23 82.6 2.2 3.1e-23 82.3 2.2 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T2SSM_b PF10741.9 GAM39889.1 - 0.076 12.8 0.1 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b DUF3251 PF11622.8 GAM39889.1 - 0.093 12.4 0.1 0.39 10.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3251) RasGAP_C PF03836.15 GAM39889.1 - 0.095 12.8 1.1 2.8 8.1 0.1 2.2 2 0 0 2 2 2 0 RasGAP C-terminus Spectrin PF00435.21 GAM39889.1 - 0.22 12.0 2.3 4.9 7.7 0.5 2.2 1 1 0 2 2 2 0 Spectrin repeat NAC PF01849.18 GAM39890.1 - 1.9e-22 79.0 0.0 7.8e-22 77.0 0.0 2.0 2 0 0 2 2 2 1 NAC domain Pes-10 PF07149.11 GAM39890.1 - 1 8.4 6.2 0.87 8.6 5.3 1.4 2 0 0 2 2 2 0 Pes-10 PGA2 PF07543.12 GAM39890.1 - 1.2 9.1 7.2 1.3 8.9 5.0 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 Ribosomal_L14e PF01929.17 GAM39891.1 - 1.1e-31 109.1 0.5 1.7e-31 108.5 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 GAM39891.1 - 2e-08 33.9 0.7 3.4e-08 33.2 0.7 1.4 1 0 0 1 1 1 1 KOW motif Prot_ATP_ID_OB PF16450.5 GAM39891.1 - 0.042 13.8 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain YIF1 PF03878.15 GAM39892.1 - 1.9e-88 296.0 2.1 2.8e-88 295.5 2.1 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 GAM39892.1 - 0.027 14.2 11.4 0.061 13.0 11.4 1.7 1 1 0 1 1 1 0 Yip1 domain SRP-alpha_N PF04086.13 GAM39893.1 - 9.2e-80 268.7 0.0 1.2e-79 268.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 GAM39893.1 - 2.6e-48 164.3 0.0 5.6e-48 163.2 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 GAM39893.1 - 2.5e-10 40.4 0.0 7.3e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 GAM39893.1 - 8.7e-07 28.2 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAM39893.1 - 0.0033 17.8 0.0 0.0082 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 GAM39893.1 - 0.0041 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 GAM39893.1 - 0.0091 16.1 0.0 0.028 14.5 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 GAM39893.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 GAM39893.1 - 0.043 13.7 0.1 0.29 11.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 GAM39893.1 - 0.045 14.3 0.0 0.18 12.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Fer4_NifH PF00142.18 GAM39893.1 - 0.06 12.8 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MMR_HSR1 PF01926.23 GAM39893.1 - 0.069 13.2 0.1 0.25 11.4 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 GAM39893.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 NTPase DUF4682 PF15733.5 GAM39893.1 - 0.61 10.7 2.6 1.1 9.9 1.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4682) Amidohydro_1 PF01979.20 GAM39894.1 - 3e-23 82.7 0.0 5.7e-23 81.8 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM39894.1 - 9.8e-09 35.2 0.1 3.8e-08 33.2 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase family Pyr_redox_2 PF07992.14 GAM39895.1 - 4.1e-39 134.6 0.0 5.6e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM39895.1 - 1.9e-14 54.0 1.9 5.4e-11 42.9 1.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM39895.1 - 2.6e-07 30.5 0.2 0.073 12.6 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 GAM39895.1 - 7e-07 28.4 1.2 0.1 11.4 0.0 3.1 2 1 1 3 3 3 3 Tryptophan halogenase HI0933_like PF03486.14 GAM39895.1 - 3.9e-06 25.8 0.4 0.0048 15.7 0.1 3.4 3 1 1 4 4 4 2 HI0933-like protein K_oxygenase PF13434.6 GAM39895.1 - 4.9e-06 25.9 0.1 5.3e-05 22.5 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 GAM39895.1 - 1.5e-05 24.2 0.3 0.0044 16.1 0.1 2.4 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAM39895.1 - 2.9e-05 24.2 0.3 0.032 14.4 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM39895.1 - 3.8e-05 23.1 0.0 0.00047 19.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM39895.1 - 7.3e-05 22.0 0.7 1.4 7.9 1.4 3.3 3 1 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAM39895.1 - 0.00066 18.9 0.1 0.31 10.1 0.1 2.5 3 0 0 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.21 GAM39895.1 - 0.0047 16.3 0.6 2 7.7 0.3 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 GAM39895.1 - 0.01 15.1 0.8 0.65 9.2 0.0 2.5 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 GAM39895.1 - 0.011 15.1 0.2 1.7 7.9 0.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 GAM39895.1 - 0.014 14.7 0.1 0.8 8.9 0.0 2.3 2 0 0 2 2 2 0 Thi4 family DUF4147 PF13660.6 GAM39895.1 - 0.058 12.9 0.2 0.37 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) DUF3662 PF12401.8 GAM39895.1 - 0.16 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) Alpha_L_fucos PF01120.17 GAM39896.1 - 6.6e-82 275.8 4.1 9e-82 275.3 4.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase MNHE PF01899.16 GAM39896.1 - 0.039 13.7 0.1 0.069 12.9 0.1 1.3 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit Glyco_hydro_43 PF04616.14 GAM39897.1 - 5.8e-33 114.4 3.3 9.1e-33 113.8 3.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 GAM39897.1 - 1.6e-23 83.5 0.5 2.3e-23 83.0 0.5 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain PD40 PF07676.12 GAM39897.1 - 0.003 17.4 1.4 0.012 15.6 1.4 2.1 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat DUF5003 PF16394.5 GAM39897.1 - 0.05 12.7 0.1 0.098 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5003) Glyco_hydro_39 PF01229.17 GAM39898.1 - 0.00045 19.0 0.1 0.00064 18.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Alpha_L_fucos PF01120.17 GAM39899.1 - 1e-78 265.2 6.9 1.4e-78 264.8 6.9 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Lipoprotein_9 PF03180.14 GAM39899.1 - 0.2 10.8 0.0 0.48 9.5 0.0 1.5 2 0 0 2 2 2 0 NLPA lipoprotein Glyco_hydro_3_C PF01915.22 GAM39900.1 - 1e-52 179.1 0.0 1.8e-52 178.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAM39900.1 - 3.9e-46 157.9 0.0 1.5e-33 116.6 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM39900.1 - 1.2e-19 70.2 0.7 2.6e-19 69.1 0.1 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.13 GAM39900.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Lipase_GDSL_2 PF13472.6 GAM39901.1 - 1.1e-16 61.8 0.4 1.5e-16 61.3 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.18 GAM39901.1 - 4.8e-13 48.8 12.2 1e-12 47.8 12.2 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.22 GAM39901.1 - 2e-08 34.5 0.2 2.9e-08 33.9 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 GAM39901.1 - 5.6e-05 22.5 0.0 7.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 OSK domain Lipase_GDSL_3 PF14606.6 GAM39901.1 - 0.0054 16.9 0.0 0.0077 16.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family zf-RAG1 PF10426.9 GAM39901.1 - 0.85 9.8 2.2 1.3 9.2 2.2 1.3 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain adh_short PF00106.25 GAM39902.1 - 3e-37 128.0 0.0 4.8e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM39902.1 - 8.7e-26 90.9 0.0 1.2e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM39902.1 - 1.2e-07 31.9 0.0 2.2e-07 30.9 0.0 1.4 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 GAM39902.1 - 0.00065 19.2 0.0 0.0016 17.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 GAM39902.1 - 0.0021 17.5 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 GAM39902.1 - 0.012 14.7 0.1 0.019 14.1 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 GAM39903.1 - 2.9e-37 128.0 0.0 3.4e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM39903.1 - 5.4e-20 72.0 0.0 6.6e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM39903.1 - 1.8e-05 24.8 0.0 2.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM39903.1 - 0.00031 20.3 0.0 0.0024 17.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM39903.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding F420_oxidored PF03807.17 GAM39903.1 - 0.015 15.8 0.4 0.028 15.0 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NUC173 PF08161.12 GAM39903.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 NUC173 domain adh_short PF00106.25 GAM39904.1 - 1.1e-08 34.8 0.1 2.6e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM39904.1 - 6.5e-05 22.9 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 KR domain F-box-like PF12937.7 GAM39904.1 - 0.00041 20.2 0.1 0.0011 18.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like adh_short_C2 PF13561.6 GAM39904.1 - 0.0046 16.5 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 GAM39904.1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 GAM39905.1 - 6.8e-16 58.1 0.0 1.7e-15 56.8 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM39905.1 - 2.4e-13 50.1 0.0 5.6e-13 48.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAM39905.1 - 2e-09 37.0 0.1 3.9e-08 32.8 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 GAM39905.1 - 4.3e-09 36.5 0.0 6.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM39905.1 - 1.3e-08 34.7 0.1 1.2e-07 31.6 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 GAM39905.1 - 3.9e-06 26.5 0.0 2.4e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAM39905.1 - 0.0049 16.0 0.0 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 GAM39905.1 - 0.091 12.2 1.4 1.9 7.9 0.0 2.4 3 0 0 3 3 3 0 short chain dehydrogenase Sugar_tr PF00083.24 GAM39906.1 - 3.6e-85 286.5 18.4 4.2e-85 286.3 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM39906.1 - 3e-16 59.3 46.1 1.7e-11 43.6 28.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.19 GAM39907.1 - 4.5e-54 182.5 0.0 6.1e-54 182.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAM39907.1 - 3.8e-28 97.8 0.0 4.8e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 GAM39907.1 - 0.0019 17.5 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 GAM39907.1 - 0.0052 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 GAM39907.1 - 0.079 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.21 GAM39907.1 - 0.094 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glycos_transf_1 PF00534.20 GAM39908.1 - 2.5e-15 56.4 0.0 6.2e-15 55.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAM39908.1 - 7.1e-12 45.9 0.0 1.3e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Taeniidae_ag PF05596.11 GAM39908.1 - 0.025 14.5 0.0 0.083 12.9 0.0 1.8 2 0 0 2 2 2 0 Taeniidae antigen Glyco_trans_1_2 PF13524.6 GAM39908.1 - 0.041 14.3 0.0 0.092 13.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 ThuA PF06283.11 GAM39908.1 - 0.17 12.1 0.1 0.42 10.8 0.0 1.6 2 0 0 2 2 2 0 Trehalose utilisation COesterase PF00135.28 GAM39909.1 - 4.4e-57 194.1 6.2 4.1e-49 167.8 0.6 2.8 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM39909.1 - 1.8e-06 28.0 0.1 1.2e-05 25.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM39909.1 - 0.0023 17.5 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DIOX_N PF14226.6 GAM39910.1 - 3.4e-18 66.5 0.1 2.8e-17 63.5 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM39910.1 - 1e-09 38.8 0.1 2.4e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 GAM39911.1 - 4e-34 118.1 21.0 4e-34 118.1 21.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily HHH PF00633.23 GAM39912.1 - 0.033 14.1 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HhH-GPD PF00730.25 GAM39912.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein HHH_5 PF14520.6 GAM39912.1 - 0.11 13.1 0.0 0.38 11.4 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain TFIIF_alpha PF05793.12 GAM39912.1 - 1.6 7.2 11.3 2.4 6.6 11.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Glyco_hydro_62 PF03664.13 GAM39913.1 - 2.6e-135 450.0 12.3 3e-135 449.8 12.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 DNA_methylase PF00145.17 GAM39914.1 - 1.2e-29 103.8 0.0 3.7e-19 69.3 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase MmgE_PrpD PF03972.14 GAM39915.1 - 5.5e-146 486.6 0.0 6.6e-146 486.3 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF1266 PF06889.11 GAM39915.1 - 0.0035 17.4 0.0 0.25 11.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1266) LtrA PF06772.11 GAM39916.1 - 1.5e-33 116.5 19.1 2.1e-33 116.0 19.1 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF1980 PF09323.10 GAM39916.1 - 0.041 13.8 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Snapin_Pallidin PF14712.6 GAM39917.1 - 1.5 9.3 16.2 0.25 11.8 1.5 4.4 3 1 1 4 4 4 0 Snapin/Pallidin MIT_C PF16565.5 GAM39917.1 - 5.6 6.9 7.9 3 7.8 1.0 3.1 4 0 0 4 4 4 0 Phospholipase D-like domain at C-terminus of MIT FAM76 PF16046.5 GAM39917.1 - 6.3 6.1 20.9 0.18 11.2 6.7 2.3 1 1 2 3 3 3 0 FAM76 protein AMP-binding PF00501.28 GAM39918.1 - 2.7e-66 223.9 0.0 3.3e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM39918.1 - 0.032 15.2 0.0 0.087 13.8 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Citrate_synt PF00285.21 GAM39919.1 - 6.7e-97 324.8 0.0 8e-97 324.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ICL PF00463.21 GAM39920.1 - 1.6e-192 640.7 0.3 1.9e-192 640.4 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 GAM39920.1 - 8.6e-09 35.2 0.1 3.2e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF2458 PF10454.9 GAM39920.1 - 0.2 11.3 1.1 0.39 10.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Patatin PF01734.22 GAM39920.1 - 0.36 11.0 1.7 6.5 6.9 0.5 2.4 2 0 0 2 2 2 0 Patatin-like phospholipase ABC_tran PF00005.27 GAM39921.1 - 4.4e-47 160.0 0.1 3.4e-24 85.9 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAM39921.1 - 1.8e-13 51.0 6.4 0.00016 21.6 0.0 4.5 4 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM39921.1 - 5e-13 49.0 1.3 0.00032 20.2 0.0 4.3 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAM39921.1 - 8.3e-08 33.0 0.0 0.0047 17.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GAM39921.1 - 1.1e-06 28.2 1.4 0.011 15.5 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM39921.1 - 2.2e-06 27.7 0.1 0.017 15.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM39921.1 - 6.6e-06 26.2 0.1 0.095 12.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Chromo PF00385.24 GAM39921.1 - 7.3e-06 25.8 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_15 PF13175.6 GAM39921.1 - 9.9e-05 22.2 1.5 0.061 13.0 1.2 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAM39921.1 - 0.00044 20.5 0.0 0.32 11.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 GAM39921.1 - 0.00046 20.4 1.0 0.25 11.4 0.1 3.5 4 0 0 4 4 3 1 Helicase HerA, central domain AAA_28 PF13521.6 GAM39921.1 - 0.0011 19.3 0.0 0.64 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain DNA_ligase_OB_2 PF14743.6 GAM39921.1 - 0.0012 18.8 0.1 0.0032 17.5 0.1 1.7 1 0 0 1 1 1 1 DNA ligase OB-like domain SbcCD_C PF13558.6 GAM39921.1 - 0.0067 16.6 0.1 3 8.1 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 GAM39921.1 - 0.015 15.2 0.2 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_13 PF13166.6 GAM39921.1 - 0.017 13.8 0.1 2.4 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAM39921.1 - 0.026 14.7 0.0 5.9 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAM39921.1 - 0.027 14.8 0.1 4.9 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 GAM39921.1 - 0.032 14.0 0.6 13 5.4 0.2 3.1 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 GAM39921.1 - 0.047 13.4 1.0 2.5 7.8 0.2 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 GAM39921.1 - 0.051 13.6 0.1 1.3 9.0 0.0 2.8 2 1 0 2 2 2 0 Dynamin family MukB PF04310.12 GAM39921.1 - 0.055 13.3 0.3 8.1 6.2 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal AAA_18 PF13238.6 GAM39921.1 - 0.064 13.8 0.1 13 6.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain ALF PF03752.13 GAM39921.1 - 0.068 13.1 5.1 1.8 8.6 1.1 3.2 3 0 0 3 3 2 0 Short repeats of unknown function MnmE_helical PF12631.7 GAM39921.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 MnmE helical domain Stork_head PF10264.9 GAM39921.1 - 0.16 12.2 0.3 0.48 10.6 0.3 1.8 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain DUF3584 PF12128.8 GAM39921.1 - 0.36 8.3 2.5 4.3 4.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_27 PF13514.6 GAM39921.1 - 0.66 9.5 2.5 13 5.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain CBP4 PF07960.11 GAM39922.1 - 4.2e-30 104.3 2.9 5.4e-30 103.9 2.9 1.1 1 0 0 1 1 1 1 CBP4 MF_alpha_N PF05436.11 GAM39923.1 - 0.24 11.3 0.1 2.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus COG6 PF06419.11 GAM39924.1 - 0.019 13.2 2.8 0.03 12.6 2.8 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Hexokinase_2 PF03727.16 GAM39924.1 - 0.071 12.5 1.6 0.2 11.0 0.1 2.3 1 1 2 3 3 3 0 Hexokinase DUF16 PF01519.16 GAM39924.1 - 0.21 12.1 2.2 0.58 10.7 2.1 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 Exonuc_VII_L PF02601.15 GAM39924.1 - 0.23 11.0 3.7 0.33 10.5 3.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 GAM39924.1 - 1 9.4 4.6 0.95 9.5 1.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 GAM39924.1 - 1.6 8.9 7.3 3.3 7.9 4.4 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FAP206 PF12018.8 GAM39924.1 - 2.2 7.7 5.2 3.1 7.2 4.1 1.7 1 1 1 2 2 2 0 Domain of unknown function Syntaxin-6_N PF09177.11 GAM39924.1 - 2.6 8.7 7.2 2.1 9.0 3.7 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal MPC PF03650.13 GAM39925.1 - 5.1e-49 165.0 0.9 7.1e-49 164.5 0.9 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers L51_S25_CI-B8 PF05047.16 GAM39926.1 - 1.7e-10 40.6 0.1 2.7e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Glyco_hydro_3_C PF01915.22 GAM39927.1 - 1.2e-40 139.7 0.0 5.6e-40 137.5 0.0 2.2 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAM39927.1 - 9.9e-40 136.9 0.0 2.7e-39 135.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain HATPase_c PF02518.26 GAM39927.1 - 3.2e-27 95.3 0.0 2.3e-26 92.5 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM39927.1 - 1.3e-25 89.8 0.3 3.2e-25 88.5 0.3 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Fn3-like PF14310.6 GAM39927.1 - 3.6e-21 75.0 0.1 1e-20 73.6 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain HisKA PF00512.25 GAM39927.1 - 2.4e-14 53.1 0.0 5e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 GAM39927.1 - 0.0054 17.1 0.1 0.4 11.1 0.0 2.9 2 0 0 2 2 2 1 HAMP domain FliG_M PF14841.6 GAM39927.1 - 0.044 14.0 0.3 0.44 10.8 0.0 2.3 2 0 0 2 2 2 0 FliG middle domain Response_reg PF00072.24 GAM39928.1 - 1.6e-19 70.1 0.0 3.6e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 GAM39928.1 - 2.2e-18 66.8 0.0 5.3e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GAM39928.1 - 2.1e-12 46.9 0.0 5.3e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 GAM39928.1 - 0.05 13.9 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 GAF domain Sel1 PF08238.12 GAM39929.1 - 5.8e-44 147.6 29.4 5.5e-07 30.1 0.5 7.5 7 0 0 7 7 7 7 Sel1 repeat PI3K_C2 PF00792.24 GAM39929.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 ANAPC3 PF12895.7 GAM39929.1 - 0.25 11.6 3.5 2.4 8.5 0.1 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Amidase PF01425.21 GAM39931.1 - 3.1e-97 326.4 0.0 2e-96 323.7 0.0 1.9 1 1 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.8 GAM39932.1 - 2.1e-08 33.4 0.1 3.5e-07 29.4 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM39932.1 - 3.7e-07 30.1 6.1 1.2e-06 28.5 6.1 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 GAM39933.1 - 1.3e-27 96.7 27.0 1.3e-27 96.7 27.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_3 PF00933.21 GAM39934.1 - 2e-78 264.0 0.0 3e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain MFS_1 PF07690.16 GAM39934.1 - 2.8e-28 98.9 32.1 2.8e-28 98.9 32.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 GAM39934.1 - 4.2e-16 59.2 0.0 8.3e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM39934.1 - 1.9e-12 47.5 0.0 1.3e-06 28.7 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM39934.1 - 3.7e-10 39.8 0.0 2.4e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM39934.1 - 3e-06 27.3 0.0 0.00024 21.2 0.0 3.0 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.22 GAM39934.1 - 2.9e-05 24.1 0.0 6.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_3 PF13302.7 GAM39934.1 - 0.0066 17.1 0.0 0.047 14.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM39934.1 - 0.085 12.8 0.0 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_CG PF14542.6 GAM39934.1 - 0.17 12.1 0.1 25 5.1 0.0 2.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase DUF4387 PF14330.6 GAM39935.1 - 1.1e-39 135.1 0.0 2.6e-39 133.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) CoA_transf_3 PF02515.17 GAM39935.1 - 5.8e-36 124.4 0.0 9.6e-35 120.4 0.0 2.1 2 0 0 2 2 2 1 CoA-transferase family III AtuA PF07287.11 GAM39935.1 - 6.3e-18 64.6 0.0 2.6e-17 62.6 0.0 1.8 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Aldedh PF00171.22 GAM39936.1 - 1e-122 410.0 3.3 1.2e-122 409.7 3.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3039 PF11238.8 GAM39936.1 - 0.084 12.6 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) Zn_clus PF00172.18 GAM39937.1 - 5.6e-10 39.2 11.9 9.6e-10 38.4 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C4H2 PF10146.9 GAM39937.1 - 1.5 9.1 10.3 0.57 10.5 5.6 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein TFIIA PF03153.13 GAM39937.1 - 2.1 8.2 9.1 3.1 7.7 9.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gti1_Pac2 PF09729.9 GAM39938.1 - 0.19 11.8 2.6 0.11 12.6 0.3 1.8 2 0 0 2 2 2 0 Gti1/Pac2 family Cwf_Cwc_15 PF04889.12 GAM39938.1 - 0.41 10.3 15.5 2 8.1 7.1 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sugar_tr PF00083.24 GAM39939.1 - 2.7e-85 287.0 21.1 3.7e-85 286.5 21.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM39939.1 - 7.8e-10 38.2 48.1 2.4e-06 26.7 14.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF4293 PF14126.6 GAM39939.1 - 1 9.6 5.7 0.72 10.1 2.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) MmgE_PrpD PF03972.14 GAM39940.1 - 1.4e-111 373.2 0.0 1.6e-111 373.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family RNase_T PF00929.24 GAM39941.1 - 9.5e-26 91.3 0.0 1.1e-25 91.0 0.0 1.1 1 0 0 1 1 1 1 Exonuclease PGM_PMM_I PF02878.16 GAM39942.1 - 2e-33 115.0 0.0 3.2e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 GAM39942.1 - 4.9e-25 87.9 0.0 8.8e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 GAM39942.1 - 8.2e-17 61.7 0.1 1.8e-16 60.6 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 GAM39942.1 - 1.3e-08 34.9 0.0 2.9e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.22 GAM39943.1 - 4.7e-11 43.6 0.0 1.4e-10 42.1 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold K_oxygenase PF13434.6 GAM39943.1 - 5.2e-09 35.7 0.0 0.0019 17.4 0.0 3.3 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) GFO_IDH_MocA_C PF02894.17 GAM39943.1 - 2.1e-05 24.5 0.0 5.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_9 PF13454.6 GAM39943.1 - 6.6e-05 22.9 0.3 1.4 8.9 0.2 3.8 3 1 1 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 GAM39943.1 - 7.3e-05 22.5 0.2 0.0079 15.8 0.3 3.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAM39943.1 - 0.00068 19.0 0.0 0.019 14.2 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM39943.1 - 0.0068 15.5 0.0 0.024 13.7 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAM39943.1 - 0.0092 15.2 0.0 0.23 10.7 0.0 2.9 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM39943.1 - 0.04 13.1 0.2 0.099 11.9 0.0 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.6 GAM39943.1 - 0.09 13.0 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 GAM39943.1 - 0.14 12.4 0.0 3.7 7.8 0.0 2.7 3 0 0 3 3 3 0 TrkA-N domain HI0933_like PF03486.14 GAM39943.1 - 0.18 10.5 0.0 0.39 9.4 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_64 PF16483.5 GAM39944.1 - 1.7e-126 422.5 4.1 2e-126 422.2 4.1 1.1 1 0 0 1 1 1 1 Beta-1,3-glucanase Aldo_ket_red PF00248.21 GAM39945.1 - 6.2e-66 222.6 0.0 7e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Claudin_3 PF06653.11 GAM39945.1 - 0.17 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like HMG_CoA_synt_N PF01154.17 GAM39947.1 - 2e-98 327.4 0.2 3.4e-98 326.6 0.2 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 GAM39947.1 - 5.9e-88 295.1 2.4 7.2e-55 186.6 0.0 2.1 1 1 1 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase C terminal TFR_dimer PF04253.15 GAM39948.1 - 1.3e-37 128.6 0.0 2.4e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 GAM39948.1 - 7.4e-18 65.0 0.0 2.4e-17 63.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 GAM39948.1 - 6.5e-16 58.1 0.1 1.4e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 PA domain Ank_2 PF12796.7 GAM39949.1 - 1.1e-67 224.5 16.0 1.1e-11 45.1 0.0 9.5 3 3 8 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM39949.1 - 9.8e-49 163.1 6.1 4.9e-08 33.4 0.0 11.4 10 2 3 13 13 13 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM39949.1 - 1.6e-47 158.9 9.9 2.7e-05 24.3 0.1 15.6 4 2 10 15 15 15 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM39949.1 - 4.6e-43 140.3 6.9 0.001 19.3 0.0 16.1 17 0 0 17 17 17 9 Ankyrin repeat Ank PF00023.30 GAM39949.1 - 1e-38 130.1 5.8 0.00088 19.6 0.0 15.2 14 2 2 16 16 16 7 Ankyrin repeat CorA PF01544.18 GAM39949.1 - 0.011 15.1 3.2 0.013 14.9 0.7 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein HisKA PF00512.25 GAM39949.1 - 0.097 12.7 0.1 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF1765 PF08578.10 GAM39950.1 - 2.5e-39 134.6 11.4 5.2e-39 133.5 11.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) THEG4 PF15834.5 GAM39950.1 - 5 7.1 6.5 10 6.1 0.5 2.6 2 0 0 2 2 2 0 Testis highly expressed protein 4 ATP_sub_h PF10775.9 GAM39951.1 - 7.3e-22 77.2 2.2 7.3e-22 77.2 2.2 1.9 2 0 0 2 2 2 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 GAM39951.1 - 4.3e-05 23.9 0.0 7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 TFIIB PF00382.19 GAM39952.1 - 8.5e-32 109.0 0.0 1.5e-18 66.6 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 GAM39952.1 - 4.3e-10 39.0 0.9 9.3e-10 37.9 0.9 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 GAM39952.1 - 0.00032 20.7 0.0 0.0012 18.9 0.0 2.0 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain HTH_5 PF01022.20 GAM39952.1 - 0.0026 17.6 0.0 0.39 10.6 0.0 2.8 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family zf-ribbon_3 PF13248.6 GAM39952.1 - 0.034 13.6 1.8 6.6 6.3 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Cyclin_C PF02984.19 GAM39952.1 - 0.041 14.0 0.0 5 7.2 0.0 2.4 2 1 0 2 2 2 0 Cyclin, C-terminal domain Sigma70_r4 PF04545.16 GAM39952.1 - 0.042 13.4 0.0 0.82 9.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 DUF1610 PF07754.11 GAM39952.1 - 0.26 11.3 2.6 1.2 9.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Prok-RING_4 PF14447.6 GAM39952.1 - 2.4 8.1 5.7 5.3 7.0 0.2 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Abhydrolase_6 PF12697.7 GAM39953.1 - 8.1e-11 42.9 0.1 1.1e-10 42.5 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAM39953.1 - 7.5e-05 22.6 0.0 0.0001 22.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 GAM39953.1 - 0.00017 21.3 0.3 0.00023 20.9 0.3 1.3 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 GAM39953.1 - 0.002 17.5 0.4 0.0043 16.4 0.4 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM39953.1 - 0.0067 16.1 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 GAM39953.1 - 0.012 15.8 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 GAM39953.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAM39953.1 - 0.026 14.3 0.0 0.06 13.1 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 GAM39953.1 - 0.046 13.6 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) CENP-R PF06729.12 GAM39953.1 - 0.097 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinetochore component, CENP-R Chlorophyllase2 PF12740.7 GAM39953.1 - 0.14 11.0 0.0 0.33 9.8 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme Surp PF01805.20 GAM39954.1 - 9.1e-09 35.2 0.0 1.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Surp module NTF2 PF02136.20 GAM39955.1 - 3.2e-32 111.6 0.1 3.6e-32 111.5 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 GAM39955.1 - 0.2 12.1 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Cg6151-P PF10233.9 GAM39956.1 - 8.2e-42 142.1 11.8 9.7e-42 141.8 11.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Goodbye PF17109.5 GAM39956.1 - 0.012 16.1 0.2 0.019 15.4 0.2 1.4 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain CitMHS PF03600.16 GAM39956.1 - 0.032 13.5 5.5 0.034 13.4 5.5 1.1 1 0 0 1 1 1 0 Citrate transporter LppX_LprAFG PF07161.13 GAM39956.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 LppX_LprAFG lipoprotein Cytochrom_B558a PF05038.13 GAM39956.1 - 0.18 11.3 1.4 0.98 9.0 0.1 2.1 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit DUF2721 PF11026.8 GAM39956.1 - 0.21 11.5 11.3 1.2 9.1 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF202 PF02656.15 GAM39956.1 - 0.48 10.9 8.8 5.9 7.4 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Phage_holin_3_6 PF07332.11 GAM39956.1 - 0.63 10.1 10.9 0.32 11.0 3.7 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3169 PF11368.8 GAM39956.1 - 0.68 9.4 8.4 0.27 10.7 4.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF3040 PF11239.8 GAM39956.1 - 1.9 8.8 6.9 6.5 7.1 2.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Aim21 PF11489.8 GAM39957.1 - 3.9e-222 740.1 67.9 3.9e-222 740.1 67.9 2.1 2 0 0 2 2 2 1 Altered inheritance of mitochondria protein 21 PBP1_TM PF14812.6 GAM39958.1 - 0.064 13.6 1.3 0.22 11.9 0.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cofac_haem_bdg PF04187.13 GAM39958.1 - 0.13 12.2 0.0 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN Glyco_hydro_18 PF00704.28 GAM39959.1 - 1.3e-86 291.2 4.4 1.7e-86 290.8 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AP_endonuc_2 PF01261.24 GAM39959.1 - 0.059 12.8 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel TspO_MBR PF03073.15 GAM39960.1 - 6.9e-46 155.6 10.1 8.5e-46 155.4 10.1 1.1 1 0 0 1 1 1 1 TspO/MBR family UQ_con PF00179.26 GAM39962.1 - 2e-41 140.9 0.0 2.2e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM39962.1 - 0.00018 21.2 0.0 0.00035 20.3 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 GAM39962.1 - 0.0042 16.7 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 GAM39962.1 - 0.074 13.3 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain Glyco_hydro_88 PF07470.13 GAM39963.1 - 1.3e-13 50.8 1.1 1.9e-13 50.3 1.1 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.16 GAM39964.1 - 6.6e-36 123.9 25.8 7.4e-35 120.5 26.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM39964.1 - 2.1e-08 33.9 5.1 2.1e-08 33.9 5.1 3.0 2 1 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB Fungal_trans PF04082.18 GAM39965.1 - 4.3e-26 91.5 0.0 5.5e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM39965.1 - 3.3e-08 33.5 11.5 5.6e-08 32.8 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 GAM39965.1 - 0.35 11.4 6.3 0.79 10.3 6.3 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region HhH-GPD PF00730.25 GAM39966.1 - 3.3e-18 66.1 0.0 9.9e-18 64.6 0.0 1.9 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 GAM39966.1 - 4.8e-10 38.8 0.0 1.6e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 GAM39966.1 - 0.084 13.5 0.0 0.39 11.4 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain AAA_11 PF13086.6 GAM39967.1 - 6.4e-65 219.5 0.6 1.8e-64 218.1 0.4 1.9 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 GAM39967.1 - 5.4e-59 199.2 0.0 1.2e-58 198.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM39967.1 - 6.5e-13 48.8 0.0 1.8e-11 44.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM39967.1 - 5.4e-09 36.5 0.0 2.3e-08 34.5 0.0 2.2 2 1 0 2 2 1 1 AAA domain DUF2075 PF09848.9 GAM39967.1 - 2.1e-07 30.6 0.3 1.6e-06 27.6 0.3 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 GAM39967.1 - 5.2e-07 29.7 0.0 0.44 10.3 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 GAM39967.1 - 2.7e-06 27.5 0.0 1.4e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 GAM39967.1 - 6.3e-05 22.6 0.3 0.00017 21.3 0.3 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 GAM39967.1 - 6.9e-05 23.1 0.2 0.0015 18.8 0.2 2.6 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 GAM39967.1 - 0.00017 21.1 0.0 0.0022 17.5 0.0 2.2 1 1 0 1 1 1 1 PhoH-like protein Flavi_DEAD PF07652.14 GAM39967.1 - 0.00057 19.9 0.1 0.0036 17.3 0.1 2.1 2 0 0 2 2 2 1 Flavivirus DEAD domain Helicase_RecD PF05127.14 GAM39967.1 - 0.00068 19.5 0.0 0.19 11.6 0.0 2.6 3 0 0 3 3 2 1 Helicase AAA_16 PF13191.6 GAM39967.1 - 0.0011 19.4 0.0 0.0032 17.9 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain T2SSE PF00437.20 GAM39967.1 - 0.002 17.2 0.0 0.0053 15.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 GAM39967.1 - 0.0083 15.7 0.1 0.12 12.0 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA PF00004.29 GAM39967.1 - 0.0085 16.5 0.2 0.056 13.9 0.0 2.5 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAM39967.1 - 0.017 14.8 0.0 0.052 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 GAM39967.1 - 0.018 14.0 0.0 0.04 12.8 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain 4HB_MCP_1 PF12729.7 GAM39967.1 - 0.024 14.2 0.1 0.051 13.1 0.1 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction IstB_IS21 PF01695.17 GAM39967.1 - 0.024 14.4 0.0 0.07 12.8 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein UvrD_C PF13361.6 GAM39967.1 - 0.026 13.9 0.0 6.6 6.0 0.0 3.0 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA_10 PF12846.7 GAM39967.1 - 0.028 13.4 0.0 0.047 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.6 GAM39967.1 - 0.028 14.9 1.7 1.7 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain TK PF00265.18 GAM39967.1 - 0.045 13.6 0.0 0.73 9.7 0.0 2.3 2 0 0 2 2 2 0 Thymidine kinase DUF241 PF03087.14 GAM39967.1 - 0.053 13.3 0.2 0.17 11.7 0.2 1.8 1 0 0 1 1 1 0 Arabidopsis protein of unknown function AAA_5 PF07728.14 GAM39967.1 - 0.055 13.5 0.0 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.6 GAM39967.1 - 0.075 12.9 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain ABC_tran PF00005.27 GAM39967.1 - 0.086 13.4 0.1 0.24 11.9 0.1 1.9 1 1 0 1 1 1 0 ABC transporter PIF1 PF05970.14 GAM39967.1 - 0.12 11.5 0.0 2.2 7.4 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase Mg_chelatase PF01078.21 GAM39967.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI YwqJ-deaminase PF14431.6 GAM39969.1 - 0.033 14.4 0.1 0.057 13.6 0.1 1.4 1 0 0 1 1 1 0 YwqJ-like deaminase DNA_photolyase PF00875.18 GAM39969.1 - 0.098 12.7 0.1 0.22 11.5 0.1 1.5 1 1 0 1 1 1 0 DNA photolyase Phage_Mu_Gam PF07352.12 GAM39969.1 - 0.27 11.1 2.8 0.15 12.0 0.4 1.8 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Cut12 PF11500.8 GAM39969.1 - 0.48 10.4 4.0 2.4 8.1 0.3 2.3 2 0 0 2 2 2 0 Spindle pole body formation-associated protein DEAD PF00270.29 GAM39970.1 - 4.1e-41 140.7 0.5 7.8e-41 139.7 0.5 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM39970.1 - 3.3e-31 107.9 0.8 1.3e-30 105.9 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM39970.1 - 8.4e-06 25.9 0.0 2.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Acyltransferase PF01553.21 GAM39972.1 - 1.4e-13 50.7 0.0 2.5e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase L31 PF09784.9 GAM39973.1 - 4.7e-39 132.9 3.2 1.2e-38 131.7 1.8 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L31 Transp_cyt_pur PF02133.15 GAM39975.1 - 1.8e-90 303.9 40.2 2.2e-90 303.6 40.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HPP PF04982.13 GAM39975.1 - 0.0092 16.2 8.4 0.014 15.6 1.0 3.2 3 0 0 3 3 3 2 HPP family DUF2457 PF10446.9 GAM39976.1 - 9 5.3 16.5 13 4.8 16.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) EBP PF05241.12 GAM39977.1 - 2.3e-66 222.6 4.0 2.7e-66 222.4 4.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein Annexin PF00191.20 GAM39978.1 - 2.8e-63 209.9 0.9 2e-17 63.0 0.1 4.1 4 0 0 4 4 4 4 Annexin DUF5638 PF18688.1 GAM39978.1 - 0.00016 22.0 0.0 0.12 12.7 0.0 2.5 2 0 0 2 2 2 2 Family of unknown function (DUF5638) DUF1645 PF07816.11 GAM39978.1 - 0.004 17.7 0.0 0.0066 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) DUF3458_C PF17432.2 GAM39978.1 - 0.046 13.1 1.3 1.1 8.5 0.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3458_C) ARM repeats RHD3 PF05879.12 GAM39978.1 - 0.053 11.7 0.6 0.15 10.1 0.6 1.6 1 1 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) DUF3574 PF12098.8 GAM39978.1 - 0.058 13.2 0.4 28 4.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3574) DUF445 PF04286.12 GAM39978.1 - 0.065 13.0 0.8 0.085 12.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF445) RLAN PF14401.6 GAM39978.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain Acetyltransf_11 PF13720.6 GAM39978.1 - 0.083 13.4 0.2 20 5.8 0.0 2.7 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 YlbE PF14003.6 GAM39978.1 - 0.23 11.9 0.6 3.4 8.2 0.1 2.5 2 0 0 2 2 2 0 YlbE-like protein DUF4790 PF16037.5 GAM39978.1 - 0.41 11.1 3.4 3.8 8.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4790) SH3_9 PF14604.6 GAM39979.1 - 3.4e-06 26.8 0.1 1.2e-05 25.1 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM39979.1 - 7.3e-05 22.3 0.2 0.00016 21.2 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAM39979.1 - 0.00064 19.3 0.5 0.004 16.8 0.0 2.6 3 0 0 3 3 3 1 Variant SH3 domain ARF7EP_C PF14949.6 GAM39979.1 - 0.0015 19.1 1.3 0.0015 19.1 1.3 3.4 4 0 0 4 4 4 1 ARF7 effector protein C-terminus Ig_GlcNase PF18368.1 GAM39980.1 - 5.3e-33 113.3 0.1 1.2e-32 112.2 0.1 1.7 1 0 0 1 1 1 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 GAM39980.1 - 1.6e-09 38.4 0.0 4e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 GAM39980.1 - 2.2e-06 27.7 0.0 4.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Mannosidase_ig PF17786.1 GAM39980.1 - 0.00073 20.1 0.2 0.004 17.7 0.0 2.3 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_C PF02836.17 GAM39980.1 - 0.0091 15.1 0.3 0.015 14.4 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 GAM39980.1 - 0.055 13.2 1.6 0.18 11.6 0.1 2.6 3 0 0 3 3 3 0 Ig-fold domain HSP20 PF00011.21 GAM39981.1 - 4.4e-18 65.3 0.1 1.4e-13 50.8 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAM39981.1 - 0.00044 19.7 0.0 0.014 15.0 0.0 2.3 2 0 0 2 2 2 1 HSP20-like domain found in ArsA FAD_binding_3 PF01494.19 GAM39982.1 - 2.9e-13 49.8 0.0 4.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM39982.1 - 0.00075 19.7 0.0 0.0026 17.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAM39982.1 - 0.0019 17.5 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 GAM39982.1 - 0.0027 17.3 0.1 0.0097 15.5 0.0 1.8 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM39982.1 - 0.0079 15.3 1.5 0.015 14.4 1.2 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM39982.1 - 0.011 15.0 0.0 0.55 9.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ub-RnfH PF03658.14 GAM39982.1 - 0.098 13.0 0.0 0.63 10.5 0.0 2.1 2 0 0 2 2 2 0 RnfH family Ubiquitin MFS_1 PF07690.16 GAM39983.1 - 2.1e-20 73.0 38.7 3.4e-18 65.7 6.4 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily TssN PF17555.2 GAM39983.1 - 8.6 5.6 6.9 3.6 6.9 2.3 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN Arylsulfotran_2 PF14269.6 GAM39984.1 - 1.2e-59 202.2 6.2 1.6e-59 201.8 6.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 GAM39984.1 - 3.2e-16 59.2 4.0 9.5e-16 57.7 4.0 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.21 GAM39984.1 - 0.021 14.7 0.0 12 6.1 0.0 3.2 2 0 0 2 2 2 0 PQQ enzyme repeat adh_short PF00106.25 GAM39985.1 - 5.2e-43 146.8 0.0 8.2e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM39985.1 - 2.7e-35 122.0 0.0 4.2e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 GAM39985.1 - 3.7e-05 23.2 0.0 7.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Methyltransf_2 PF00891.18 GAM39986.1 - 7.2e-16 58.1 0.0 2e-15 56.6 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 GAM39986.1 - 0.068 13.9 0.1 0.35 11.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain FAD_binding_3 PF01494.19 GAM39987.1 - 2e-17 63.5 0.4 6.5e-12 45.4 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAM39987.1 - 5.6e-07 29.1 0.4 0.00034 20.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM39987.1 - 1.1e-06 28.0 1.9 1.7e-06 27.4 1.9 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM39987.1 - 1.4e-06 28.4 0.6 3.8e-06 27.0 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM39987.1 - 2.4e-06 27.4 2.4 5.1e-05 23.0 1.3 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM39987.1 - 8.6e-05 21.4 0.9 0.00017 20.4 1.0 1.4 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 GAM39987.1 - 0.00042 19.5 0.2 0.0011 18.0 0.2 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 GAM39987.1 - 0.00052 19.4 0.4 0.0031 16.8 0.2 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 GAM39987.1 - 0.00097 18.6 0.2 0.0016 17.9 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM39987.1 - 0.0013 18.8 0.2 0.016 15.2 0.2 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding GIDA PF01134.22 GAM39987.1 - 0.0013 17.9 1.2 0.002 17.3 1.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 GAM39987.1 - 0.0015 17.8 0.4 0.0026 17.0 0.4 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 GAM39987.1 - 0.0043 16.4 0.1 0.018 14.4 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 GAM39987.1 - 0.006 15.5 0.2 0.27 10.1 0.1 2.3 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 GAM39987.1 - 0.01 15.1 0.4 0.018 14.3 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM39987.1 - 0.027 15.0 2.4 0.051 14.1 1.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 GAM39987.1 - 0.04 13.8 0.1 0.065 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MCRA PF06100.11 GAM39987.1 - 0.17 10.7 0.4 0.25 10.1 0.4 1.2 1 0 0 1 1 1 0 MCRA family Questin_oxidase PF14027.6 GAM39988.1 - 3.9e-73 247.0 0.1 5e-73 246.6 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like ketoacyl-synt PF00109.26 GAM39989.1 - 3.8e-76 256.0 0.0 1.1e-75 254.5 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 GAM39989.1 - 5.9e-58 196.4 1.9 1e-57 195.6 0.1 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 GAM39989.1 - 1.2e-38 133.5 0.0 2.4e-38 132.5 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM39989.1 - 1.1e-36 125.5 0.0 9.2e-36 122.4 0.0 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 GAM39989.1 - 8.4e-25 88.2 0.0 2.1e-24 86.9 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 GAM39989.1 - 3.2e-18 65.8 7.7 1.2e-11 44.8 0.9 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 GAM39989.1 - 1.4e-06 27.7 0.0 2.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.7 GAM39989.1 - 9.9e-05 23.0 0.2 0.0068 17.0 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 GAM39989.1 - 0.00023 21.6 0.1 0.00078 19.9 0.1 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 GAM39989.1 - 0.00076 18.9 0.2 0.0016 17.8 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain MFS_1 PF07690.16 GAM39990.1 - 8.9e-27 93.9 59.6 8.9e-27 93.9 59.6 3.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM39990.1 - 1.6e-08 33.9 14.7 1.6e-08 33.9 14.7 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter Mannosyl_trans PF05007.13 GAM39991.1 - 1.1e-75 254.9 19.6 1.6e-75 254.3 19.6 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) NIBRIN_BRCT_II PF16508.5 GAM39993.1 - 1.6e-37 128.4 0.0 4.9e-37 126.9 0.0 1.9 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 GAM39993.1 - 3.5e-08 33.7 0.4 1.4e-07 31.7 0.6 2.0 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 GAM39993.1 - 0.057 13.7 0.2 0.69 10.3 0.2 2.5 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 PF16770.5 GAM39993.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Epimerase PF01370.21 GAM39994.1 - 1.6e-13 50.7 0.0 2.6e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM39994.1 - 1.1e-06 27.9 0.0 5e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAM39994.1 - 1.5e-05 25.0 0.0 2.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAM39994.1 - 7.5e-05 22.3 0.1 0.00015 21.3 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAM39994.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.16 GAM39996.1 - 2.1e-27 96.0 17.9 6.4e-25 87.8 17.8 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily CMD PF02627.20 GAM39997.1 - 2.3e-21 75.6 0.2 4.3e-21 74.7 0.1 1.5 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family NAD_binding_2 PF03446.15 GAM39998.1 - 1.3e-33 116.4 0.0 1.8e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAM39998.1 - 2.2e-14 53.7 0.0 3.3e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 GAM39998.1 - 3.4e-06 27.5 0.1 7.8e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 GAM39998.1 - 1.6e-05 24.0 0.0 2.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 GAM39998.1 - 0.044 14.6 0.1 0.075 13.9 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 GAM39998.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Aldedh PF00171.22 GAM39999.1 - 2.8e-161 537.1 0.1 3.1e-161 537.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IMS PF00817.20 GAM40001.1 - 3.5e-43 147.2 1.8 4.5e-43 146.8 0.4 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 GAM40001.1 - 1.3e-14 54.9 0.1 2.8e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 GAM40001.1 - 1e-06 28.7 0.0 2.8e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif BAF PF02961.14 GAM40001.1 - 0.023 15.1 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 Barrier to autointegration factor Vps36-NZF-N PF16988.5 GAM40001.1 - 0.034 13.5 0.9 0.078 12.4 0.1 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF4612 PF15389.6 GAM40001.1 - 1.4 10.0 0.0 1.4 10.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4612) Hemerythrin PF01814.23 GAM40002.1 - 6.5e-10 39.7 1.6 1e-09 39.1 1.6 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain SQS_PSY PF00494.19 GAM40003.1 - 8.2e-38 130.4 0.0 1.1e-37 130.0 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF2951 PF11166.8 GAM40003.1 - 0.0034 17.6 0.5 0.9 9.8 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2951) Synaptobrevin PF00957.21 GAM40003.1 - 0.0054 16.5 0.2 0.17 11.7 0.1 2.7 3 0 0 3 3 3 1 Synaptobrevin DUF5383 PF17355.2 GAM40003.1 - 0.022 15.1 0.2 0.18 12.2 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Insulin_TMD PF17870.1 GAM40003.1 - 0.045 13.8 0.1 0.045 13.8 0.1 2.4 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment DnaJ-X PF14308.6 GAM40004.1 - 7.2e-78 260.8 2.5 7.2e-78 260.8 2.5 3.1 3 2 1 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.31 GAM40004.1 - 4.4e-25 87.6 0.2 1.2e-24 86.2 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain HET PF06985.11 GAM40005.1 - 1.1e-05 25.8 0.5 0.019 15.3 0.0 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DNA_pol_phi PF04931.13 GAM40005.1 - 6.1 4.8 14.3 8.3 4.4 14.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GAM40005.1 - 9.3 5.6 9.2 14 4.9 9.2 1.2 1 0 0 1 1 1 0 SDA1 Peptidase_A4 PF01828.17 GAM40006.1 - 2.2e-75 252.7 11.7 2.6e-75 252.5 11.7 1.1 1 0 0 1 1 1 1 Peptidase A4 family Translin PF01997.16 GAM40007.1 - 1e-74 250.9 0.1 1.2e-74 250.7 0.1 1.0 1 0 0 1 1 1 1 Translin family DUF3450 PF11932.8 GAM40007.1 - 0.015 14.6 0.1 0.049 12.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) RPEL PF02755.15 GAM40008.1 - 5e-21 73.7 19.8 2.8e-08 33.2 2.0 3.6 3 0 0 3 3 3 3 RPEL repeat CP12 PF02672.15 GAM40008.1 - 0.036 14.8 2.6 1.1 10.0 0.1 2.8 3 0 0 3 3 3 0 CP12 domain THOC7 PF05615.13 GAM40008.1 - 0.16 12.3 5.9 0.13 12.6 2.6 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 FANCI_S1-cap PF14674.6 GAM40008.1 - 0.86 9.7 3.7 5.4 7.2 0.2 2.8 3 0 0 3 3 3 0 FANCI solenoid 1 cap MFS_1 PF07690.16 GAM40009.1 - 4.1e-40 137.8 51.0 3.2e-39 134.9 51.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily NAD_binding_4 PF07993.12 GAM40009.1 - 6e-34 117.4 0.0 1e-33 116.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAM40009.1 - 1.9e-33 115.7 0.0 3.3e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme TRI12 PF06609.13 GAM40009.1 - 3.4e-15 55.5 23.5 1e-14 54.0 23.5 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Epimerase PF01370.21 GAM40009.1 - 1.8e-11 43.9 0.0 6.7e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAM40009.1 - 1.4e-07 31.8 0.0 3.3e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NmrA PF05368.13 GAM40009.1 - 0.03 13.9 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family OATP PF03137.20 GAM40009.1 - 1.9 6.7 12.5 0.043 12.1 0.6 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Aldo_ket_red PF00248.21 GAM40010.1 - 5e-73 245.9 0.0 5.7e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HAMP_N3 PF18575.1 GAM40010.1 - 0.12 12.0 0.7 0.48 10.0 0.0 2.3 3 0 0 3 3 3 0 HAMP N-terminal domain 3 NAD_binding_4 PF07993.12 GAM40011.1 - 1.2e-30 106.6 0.0 1.9e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAM40011.1 - 4.8e-15 55.1 0.2 7.9e-15 54.4 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAM40011.1 - 3.2e-12 46.4 0.0 5.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAM40011.1 - 1.8e-05 25.0 0.0 6e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 GAM40011.1 - 0.0011 18.4 0.0 0.0025 17.3 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 GAM40011.1 - 0.0012 18.7 0.0 0.012 15.6 0.0 2.1 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 GAM40011.1 - 0.046 12.8 0.0 13 4.8 0.0 2.8 3 0 0 3 3 3 0 RmlD substrate binding domain Fungal_trans PF04082.18 GAM40012.1 - 8.5e-15 54.5 0.0 1.6e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40012.1 - 0.0056 16.8 3.1 0.014 15.5 3.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 GAM40013.1 - 2.5e-40 138.7 0.0 3.7e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM40013.1 - 2.3e-35 122.2 0.0 4.2e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Tyrosinase PF00264.20 GAM40014.1 - 1.3e-34 120.5 5.7 1.9e-34 119.9 5.7 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase ADH_N PF08240.12 GAM40016.1 - 1.2e-18 66.9 2.5 2.1e-18 66.2 2.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM40016.1 - 4.5e-09 36.4 0.0 8e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAM40016.1 - 0.0004 19.8 0.1 0.0007 19.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAM40016.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.18 GAM40017.1 - 1.4e-18 66.9 0.4 2.5e-18 66.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Amdase PF17645.1 GAM40018.1 - 3.1e-16 59.7 0.1 3.8e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase DUF3802 PF12290.8 GAM40018.1 - 0.0048 17.4 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3802) PIN_4 PF13638.6 GAM40019.1 - 0.0066 16.7 0.0 0.49 10.7 0.0 2.3 2 0 0 2 2 2 2 PIN domain NUDE_C PF04880.13 GAM40019.1 - 0.87 10.0 5.4 3.7 8.0 1.7 2.3 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Rhodanese PF00581.20 GAM40020.1 - 2.3e-18 66.7 0.0 2.5e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain zf-ANAPC11 PF12861.7 GAM40021.1 - 9.8e-47 157.0 9.6 1.2e-46 156.7 9.6 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 GAM40021.1 - 2.9e-21 75.5 10.0 4.2e-21 75.0 10.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAM40021.1 - 3e-08 33.8 14.5 8e-07 29.3 14.6 2.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAM40021.1 - 6.9e-05 22.8 9.3 0.00052 20.0 5.6 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 GAM40021.1 - 0.00075 19.2 10.8 0.025 14.4 7.5 2.7 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 GAM40021.1 - 0.0016 18.3 13.3 0.0063 16.4 13.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM40021.1 - 0.0019 18.0 11.4 0.0038 17.1 6.7 2.3 1 1 2 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM40021.1 - 0.0021 17.9 16.0 0.0057 16.5 12.6 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAM40021.1 - 0.0028 17.8 1.6 0.0028 17.8 1.6 2.5 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 GAM40021.1 - 0.011 15.9 15.1 0.2 11.9 15.1 3.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 GAM40021.1 - 0.028 14.4 14.6 0.22 11.5 14.7 2.5 1 1 1 2 2 2 0 zinc-RING finger domain zf-HIT PF04438.16 GAM40021.1 - 0.035 14.0 4.0 0.069 13.0 0.7 2.4 2 0 0 2 2 2 0 HIT zinc finger YacG PF03884.14 GAM40021.1 - 0.037 13.8 4.0 0.28 11.0 0.2 2.7 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG DUF2256 PF10013.9 GAM40021.1 - 0.14 12.3 0.2 0.14 12.3 0.2 3.2 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) TerY_C PF15616.6 GAM40021.1 - 0.19 11.9 6.0 0.36 11.0 6.1 1.3 1 1 0 1 1 1 0 TerY-C metal binding domain DUF2039 PF10217.9 GAM40021.1 - 0.23 11.8 0.3 0.23 11.8 0.3 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Rad50_zn_hook PF04423.14 GAM40021.1 - 0.26 11.2 4.2 0.48 10.3 0.0 2.4 2 1 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 GAM40021.1 - 0.3 11.0 13.7 3 7.8 10.4 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 GAM40021.1 - 0.75 9.5 14.6 0.37 10.4 10.4 2.4 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 GAM40021.1 - 0.89 9.5 12.2 4.7 7.2 12.2 2.2 1 1 0 1 1 1 0 PHD-finger zf-C2H2_9 PF16293.5 GAM40021.1 - 0.93 9.4 6.7 4 7.4 0.0 3.2 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-RING_11 PF17123.5 GAM40021.1 - 2.2 8.1 13.3 3.5 7.5 10.4 2.5 2 1 0 2 2 2 0 RING-like zinc finger zf-RING-like PF08746.11 GAM40021.1 - 4.8 7.6 11.5 26 5.2 11.5 2.2 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.7 GAM40021.1 - 6.3 7.0 12.9 9.8 6.4 11.1 2.2 1 1 1 2 2 2 0 RING-variant domain DUF560 PF04575.13 GAM40022.1 - 0.17 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF560) Kinesin PF00225.23 GAM40023.1 - 3.4e-109 364.8 1.4 1.1e-108 363.2 1.4 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAM40023.1 - 2.5e-26 92.4 0.0 2.2e-25 89.3 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 GAM40023.1 - 7.9e-10 39.2 5.1 7.9e-10 39.2 5.1 4.8 3 1 2 5 5 5 2 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.12 GAM40023.1 - 4.7e-05 23.5 0.2 4.7e-05 23.5 0.2 5.3 1 1 3 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 GAM40023.1 - 0.52 10.1 49.2 0.4 10.5 0.2 4.5 1 1 4 5 5 5 0 Apolipoprotein A1/A4/E domain UPF0183 PF03676.14 GAM40024.1 - 5e-57 194.0 0.0 7.9e-37 127.5 0.0 3.0 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) ECH_1 PF00378.20 GAM40025.1 - 2.7e-05 23.6 0.0 2.8e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAM40026.1 - 5.6e-13 48.8 0.0 7.5e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM40026.1 - 1e-06 28.5 0.0 1.3e-06 28.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ADH_zinc_N PF00107.26 GAM40027.1 - 7.5e-27 93.9 0.1 1.4e-26 93.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM40027.1 - 1e-17 65.4 0.1 1.9e-17 64.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM40027.1 - 2.7e-05 24.0 0.0 0.00011 22.1 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ribosomal_S11 PF00411.19 GAM40027.1 - 0.0023 18.3 0.2 0.81 10.1 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S11 2-Hacid_dh_C PF02826.19 GAM40027.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SIS_2 PF13580.6 GAM40027.1 - 0.11 12.5 0.2 0.24 11.4 0.2 1.6 1 0 0 1 1 1 0 SIS domain tRNA-synt_1 PF00133.22 GAM40028.1 - 6.6e-162 539.9 0.0 8.6e-162 539.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAM40028.1 - 9.9e-22 77.5 1.3 2.3e-21 76.3 1.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAM40028.1 - 1.3e-19 70.2 0.2 4.9e-12 45.3 0.0 4.2 3 1 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 GAM40028.1 - 0.0052 16.2 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 GAM40028.1 - 0.023 14.6 4.5 0.065 13.1 4.5 1.9 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.6 GAM40028.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Bac_rhodopsin PF01036.18 GAM40029.1 - 1.9e-36 125.8 13.4 2.5e-36 125.3 13.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein SUR7 PF06687.12 GAM40029.1 - 1.4 8.5 9.6 7.1 6.2 0.3 3.1 3 0 0 3 3 3 0 SUR7/PalI family DUF805 PF05656.14 GAM40029.1 - 2.4 8.6 13.9 2.4 8.6 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF805) RTA1 PF04479.13 GAM40030.1 - 1.5e-69 233.7 14.8 1.5e-69 233.7 14.8 1.7 2 0 0 2 2 2 1 RTA1 like protein DUF3483 PF11982.8 GAM40030.1 - 0.22 11.1 8.6 0.064 12.9 5.2 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3483) Fungal_trans_2 PF11951.8 GAM40031.1 - 2.1e-10 40.0 0.7 3.3e-10 39.4 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40031.1 - 1e-06 28.7 7.0 2e-06 27.8 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PsaA_PsaB PF00223.19 GAM40031.1 - 0.044 12.0 0.1 0.066 11.4 0.1 1.2 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Ribosomal_S5 PF00333.20 GAM40034.1 - 3.6e-27 94.1 2.2 6.5e-27 93.3 0.8 2.1 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 GAM40034.1 - 3.2e-23 80.9 0.0 5.3e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Phage_tail_NK PF16532.5 GAM40034.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales Mpv17_PMP22 PF04117.12 GAM40035.1 - 8.8e-22 77.1 1.5 9.2e-22 77.0 0.3 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family IF4E PF01652.18 GAM40036.1 - 5.8e-54 182.2 0.4 7.5e-54 181.8 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PTR2 PF00854.21 GAM40037.1 - 8.7e-92 308.0 6.7 1.6e-91 307.1 6.7 1.4 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 GAM40037.1 - 6.2e-08 32.0 14.0 6.2e-08 32.0 14.0 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM40038.1 - 4.6e-07 29.1 0.1 9.5e-07 28.1 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40038.1 - 1.7e-06 28.0 9.7 4.3e-06 26.8 9.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrolase PF00702.26 GAM40040.1 - 0.00062 20.1 0.0 0.003 17.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAM40040.1 - 0.0034 17.5 0.0 0.011 15.9 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Beta_elim_lyase PF01212.21 GAM40041.1 - 5.1e-65 219.7 0.0 6e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GAM40041.1 - 0.0013 18.1 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 GAM40041.1 - 0.013 14.1 0.0 0.02 13.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme AA_permease PF00324.21 GAM40042.1 - 7.3e-113 377.7 40.4 9e-113 377.4 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM40042.1 - 3.8e-31 108.4 39.8 5.1e-31 107.9 39.8 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_MOT1 PF16983.5 GAM40042.1 - 0.0044 17.4 5.2 0.0044 17.4 5.2 2.8 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily adh_short PF00106.25 GAM40043.1 - 1.8e-44 151.6 0.1 2.3e-44 151.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40043.1 - 1.3e-29 103.4 0.0 1.6e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40043.1 - 1.9e-07 31.1 0.0 2.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAM40043.1 - 0.00021 21.2 0.0 0.0003 20.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM40043.1 - 0.0049 16.4 0.1 0.011 15.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family BcrAD_BadFG PF01869.20 GAM40043.1 - 0.024 14.2 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family RmlD_sub_bind PF04321.17 GAM40043.1 - 0.033 13.3 0.1 0.063 12.4 0.0 1.4 2 0 0 2 2 2 0 RmlD substrate binding domain DAO PF01266.24 GAM40044.1 - 2.2e-42 145.9 0.1 2.7e-42 145.6 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAM40044.1 - 3.1e-06 26.6 0.0 5.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 GAM40044.1 - 1.2e-05 24.8 0.1 0.044 13.0 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM40044.1 - 5.8e-05 23.3 1.1 0.00013 22.1 1.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM40044.1 - 0.00014 21.2 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM40044.1 - 0.00062 19.8 0.3 0.014 15.4 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 GAM40044.1 - 0.0098 15.2 0.1 1.9 7.7 0.0 2.5 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase DUF3846 PF12957.7 GAM40044.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) Lycopene_cycl PF05834.12 GAM40044.1 - 0.012 14.7 0.3 0.023 13.7 0.3 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAM40044.1 - 0.03 13.4 0.8 0.052 12.6 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 GAM40044.1 - 0.034 12.8 0.2 1.3 7.6 0.4 2.1 2 0 0 2 2 2 0 HI0933-like protein MCRA PF06100.11 GAM40044.1 - 0.079 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 MCRA family GIDA PF01134.22 GAM40044.1 - 0.22 10.6 0.2 0.31 10.1 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Zn_clus PF00172.18 GAM40045.1 - 2.1e-10 40.6 9.2 4.5e-10 39.5 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM40045.1 - 0.008 15.2 0.1 0.037 13.0 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain IL11 PF07400.11 GAM40045.1 - 0.3 10.7 3.4 1.1 8.8 0.3 2.4 2 0 0 2 2 2 0 Interleukin 11 UDPGP PF01704.18 GAM40046.1 - 1.1e-178 594.1 0.0 3.4e-178 592.5 0.0 1.7 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.6 GAM40046.1 - 0.079 11.8 2.0 1.6 7.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4301) C2 PF00168.30 GAM40047.1 - 3.8e-76 252.0 0.0 1.6e-19 70.1 0.0 5.5 5 0 0 5 5 5 5 C2 domain NT-C2 PF10358.9 GAM40047.1 - 0.026 14.3 0.4 1.6 8.4 0.1 3.0 3 0 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins Pyr_redox_2 PF07992.14 GAM40048.1 - 2.7e-31 108.9 0.0 3.2e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM40048.1 - 6.2e-08 33.1 0.8 2e-06 28.2 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF498 PF04430.14 GAM40048.1 - 0.00041 20.4 0.0 0.0011 19.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) NAD_binding_9 PF13454.6 GAM40048.1 - 0.092 12.7 0.5 8.8 6.3 0.0 3.1 3 1 1 4 4 4 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 GAM40048.1 - 0.14 11.3 0.1 0.34 10.0 0.1 1.6 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GST_N_2 PF13409.6 GAM40049.1 - 2.5e-23 82.2 0.0 2e-22 79.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM40049.1 - 5.4e-15 55.2 0.0 3.2e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM40049.1 - 5.7e-05 23.3 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM40049.1 - 0.00041 20.7 0.0 0.0062 16.9 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM40049.1 - 0.00073 19.7 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 GAM40052.1 - 4.7e-11 42.2 13.6 4.7e-11 42.2 13.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Haem_oxygenas_2 PF14518.6 GAM40053.1 - 7.1e-44 149.7 1.2 1.1e-43 149.0 0.2 1.9 2 0 0 2 2 2 1 Iron-containing redox enzyme MFS_1 PF07690.16 GAM40054.1 - 2.8e-48 164.6 50.6 2.8e-46 158.1 50.6 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM40054.1 - 0.00057 18.9 14.0 0.00057 18.9 14.0 2.9 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 GAM40054.1 - 0.01 14.7 23.7 0.043 12.7 8.1 2.3 2 0 0 2 2 2 0 MFS_1 like family DUF2070 PF09843.9 GAM40054.1 - 0.064 11.5 22.8 0.0048 15.2 12.6 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) CD225 PF04505.12 GAM40054.1 - 0.31 11.2 0.0 0.31 11.2 0.0 3.9 3 0 0 3 3 3 0 Interferon-induced transmembrane protein tRNA-synt_2 PF00152.20 GAM40055.1 - 5.1e-53 180.2 0.0 8.2e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DIOX_N PF14226.6 GAM40055.1 - 7.4e-05 23.5 0.0 0.00021 22.1 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal tRNA_anti-codon PF01336.25 GAM40055.1 - 0.012 15.6 0.1 0.028 14.4 0.0 1.6 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain 2OG-FeII_Oxy PF03171.20 GAM40055.1 - 0.058 13.9 0.0 0.21 12.1 0.0 1.9 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Trp_DMAT PF11991.8 GAM40056.1 - 9.3e-101 337.8 0.0 1.1e-100 337.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Zn_clus PF00172.18 GAM40057.1 - 0.0003 20.8 7.1 0.00051 20.1 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-PHD-like PF15446.6 GAM40057.1 - 0.08 12.6 5.4 0.18 11.4 5.4 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain adh_short PF00106.25 GAM40058.1 - 1.8e-24 86.3 0.3 2.6e-24 85.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40058.1 - 7.7e-23 81.3 0.2 1e-22 80.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 GAM40058.1 - 8.5e-10 38.8 0.6 2.5e-09 37.3 0.6 1.7 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 GAM40058.1 - 5.9e-09 36.1 0.0 1.2e-08 35.0 0.0 1.5 2 0 0 2 2 2 1 KR domain NmrA PF05368.13 GAM40058.1 - 0.00044 19.9 0.2 0.00069 19.2 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 GAM40058.1 - 0.0033 17.7 0.2 0.012 15.8 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.19 GAM40058.1 - 0.052 12.5 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Amidase PF01425.21 GAM40059.1 - 2e-86 290.7 0.0 5.1e-86 289.4 0.0 1.6 1 1 0 1 1 1 1 Amidase zf-CCCH PF00642.24 GAM40060.1 - 3.3e-08 33.3 20.0 3e-07 30.2 2.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 GAM40060.1 - 0.00084 19.1 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 GAM40060.1 - 0.0058 16.7 3.3 0.0058 16.7 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 GAM40060.1 - 0.0098 16.6 3.0 0.5 11.1 0.2 2.4 2 0 0 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 GAM40060.1 - 0.95 9.7 7.7 0.2 11.9 1.4 2.3 1 1 0 2 2 2 0 Zinc-finger containing family DUF4366 PF14283.6 GAM40061.1 - 0.014 15.4 0.0 0.017 15.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DcuA_DcuB PF03605.14 GAM40061.1 - 0.016 14.1 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Vezatin PF12632.7 GAM40061.1 - 0.021 14.2 0.1 0.039 13.3 0.1 1.4 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes DUF2749 PF10907.8 GAM40061.1 - 0.038 14.2 0.3 0.093 12.9 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) DUF2207 PF09972.9 GAM40061.1 - 0.079 11.7 0.0 0.087 11.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3593 PF12159.8 GAM40061.1 - 0.09 12.8 0.0 3.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) RskA PF10099.9 GAM40061.1 - 0.1 12.9 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA PBP_N PF17093.5 GAM40061.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus FYVE PF01363.21 GAM40062.1 - 5.4e-21 74.5 1.7 5.4e-21 74.5 1.7 3.2 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 GAM40062.1 - 2.4e-08 34.2 4.8 2.4e-08 34.2 4.8 3.4 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 GAM40062.1 - 7.9e-06 25.6 4.0 7.9e-06 25.6 4.0 3.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAM40062.1 - 0.00013 21.6 4.6 0.00013 21.6 4.6 2.9 3 0 0 3 3 3 1 RING-like zinc finger FYVE_2 PF02318.16 GAM40062.1 - 0.0026 18.0 0.4 0.0026 18.0 0.4 2.4 2 0 0 2 2 2 1 FYVE-type zinc finger zf-C3HC4 PF00097.25 GAM40062.1 - 0.0041 16.9 4.4 0.0041 16.9 4.4 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAM40062.1 - 0.0066 16.7 6.2 0.0066 16.7 6.2 3.4 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAM40062.1 - 0.015 15.3 3.8 0.015 15.3 3.8 3.8 3 0 0 3 3 3 0 RING-type zinc-finger Zn-C2H2_12 PF18112.1 GAM40062.1 - 0.74 10.3 8.5 4.1 7.9 0.1 3.2 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain UBZ_FAAP20 PF15750.5 GAM40062.1 - 2.4 8.2 5.7 5.8 6.9 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger Fungal_trans PF04082.18 GAM40063.1 - 1.4e-06 27.6 0.0 2.9e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40063.1 - 1.9e-05 24.7 13.2 3.2e-05 23.9 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NPV_P10 PF05531.12 GAM40063.1 - 0.25 11.8 1.6 14 6.3 0.1 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein APH PF01636.23 GAM40064.1 - 1.8e-09 37.9 0.0 2.7e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM40064.1 - 1.4e-08 34.6 0.4 3.2e-08 33.4 0.4 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 GAM40064.1 - 7.7e-06 25.4 0.2 1.3e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 GAM40064.1 - 2.8e-05 23.2 0.3 3.9e-05 22.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 GAM40064.1 - 0.097 11.9 0.2 0.25 10.5 0.3 1.7 2 1 0 2 2 2 0 Fructosamine kinase LIM_bind PF01803.16 GAM40064.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 LIM-domain binding protein UQ_con PF00179.26 GAM40066.1 - 1.7e-44 150.9 0.0 1.9e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TFIIIC_delta PF12657.7 GAM40067.1 - 1.2e-40 139.4 0.7 2.1e-40 138.6 0.7 1.4 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Cation_efflux PF01545.21 GAM40068.1 - 1.4e-46 158.8 13.7 1.4e-46 158.8 13.7 4.1 4 1 1 5 5 5 1 Cation efflux family Oxidored_FMN PF00724.20 GAM40069.1 - 3.7e-57 194.1 0.0 4.9e-56 190.4 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glyco_trans_1_4 PF13692.6 GAM40070.1 - 5.8e-06 26.8 0.0 1.7e-05 25.2 0.0 1.8 2 1 1 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAM40070.1 - 0.00017 21.7 0.0 0.00043 20.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 GAM40070.1 - 0.00019 21.8 0.0 0.0011 19.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAM40070.1 - 0.00098 18.7 0.0 0.0022 17.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 RMI1_N PF08585.12 GAM40070.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 RecQ mediated genome instability protein Thiolase_N PF00108.23 GAM40071.1 - 6.3e-94 314.2 2.7 9.7e-94 313.5 2.7 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAM40071.1 - 1.7e-38 131.0 0.5 1.7e-38 131.0 0.5 2.0 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAM40071.1 - 0.00015 21.4 3.5 0.00026 20.7 2.4 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain 7TMR-HDED PF07697.11 GAM40071.1 - 0.011 15.9 0.2 0.029 14.5 0.2 1.5 1 1 0 1 1 1 0 7TM-HD extracellular Inhibitor_I66 PF16850.5 GAM40071.1 - 0.1 12.4 0.1 20 5.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase inhibitor I66 ACP_syn_III PF08545.10 GAM40071.1 - 4.4 7.2 6.3 27 4.7 0.1 3.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.26 GAM40072.1 - 1.7e-51 173.5 0.0 1.9e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM40072.1 - 0.0026 17.5 0.0 0.0029 17.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAM40072.1 - 0.094 13.0 0.0 0.15 12.3 0.0 1.4 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.23 GAM40073.1 - 7e-112 373.6 0.2 1.9e-111 372.2 0.2 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAM40073.1 - 3.5e-26 91.9 0.0 1e-25 90.4 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding TFA2_Winged_2 PF18121.1 GAM40073.1 - 9.3 6.0 6.5 4.2 7.1 0.3 3.6 4 0 0 4 4 4 0 TFA2 Winged helix domain 2 Methyltransf_2 PF00891.18 GAM40074.1 - 2.3e-20 72.8 0.0 3.5e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 GAM40074.1 - 0.0082 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 GAM40074.1 - 0.12 12.4 0.1 0.61 10.2 0.0 2.3 1 1 1 2 2 2 0 Dimerisation domain ketoacyl-synt PF00109.26 GAM40075.1 - 1.9e-76 257.0 0.0 4.3e-76 255.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAM40075.1 - 1.7e-37 129.7 0.1 2.9e-37 128.9 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 GAM40075.1 - 2.6e-37 128.9 3.2 1.9e-36 126.1 0.0 3.6 4 1 0 4 4 4 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ketoacyl-synt_C PF02801.22 GAM40075.1 - 2.6e-32 111.3 2.5 5.8e-32 110.2 2.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 GAM40075.1 - 2.7e-10 40.0 0.0 6e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 GAM40075.1 - 2e-09 37.6 4.0 5.6e-09 36.2 2.9 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 GAM40075.1 - 6.1e-09 36.3 0.0 1.5e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 GAM40075.1 - 0.00024 20.5 0.1 0.00068 19.1 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Aminotran_4 PF01063.19 GAM40076.1 - 1e-33 117.1 0.0 1.3e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV MFS_1 PF07690.16 GAM40077.1 - 1.8e-29 102.8 36.2 5.7e-29 101.1 34.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM40077.1 - 0.0095 15.3 19.8 0.097 11.9 19.8 2.2 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Saf_2TM PF18303.1 GAM40077.1 - 0.1 12.2 0.5 0.54 9.8 0.1 2.4 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_C1_2 PF03051.15 GAM40078.1 - 8.3e-159 529.0 0.0 9.6e-159 528.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 GAM40078.1 - 3.5e-08 33.8 0.1 0.00099 19.2 0.2 2.5 2 0 0 2 2 2 2 Papain family cysteine protease DUF4296 PF14129.6 GAM40078.1 - 0.035 14.7 0.0 0.075 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) FAD_binding_3 PF01494.19 GAM40080.1 - 3.9e-20 72.4 0.3 3.9e-11 42.8 0.1 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAM40080.1 - 0.00013 22.1 0.3 0.00077 19.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAM40080.1 - 0.00076 18.6 0.3 0.03 13.4 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAM40080.1 - 0.0016 17.8 0.0 0.0047 16.2 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM40080.1 - 0.011 15.4 0.7 0.068 12.7 0.4 2.0 1 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM40080.1 - 0.011 16.3 0.0 0.14 12.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM40080.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 GAM40080.1 - 0.025 13.5 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 GAM40080.1 - 0.036 12.8 0.0 0.049 12.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 GAM40080.1 - 0.063 12.5 0.1 0.094 11.9 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Caps_synth PF05704.12 GAM40081.1 - 4.7e-11 42.6 0.0 1.1e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 GAM40081.1 - 0.00029 21.4 0.0 0.00091 19.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif p450 PF00067.22 GAM40082.1 - 2.6e-54 184.7 0.0 1.8e-46 158.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Glyco_hydro_31 PF01055.26 GAM40083.1 - 1.9e-155 518.4 3.0 2.6e-155 517.9 3.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 GAM40083.1 - 1.5e-39 134.8 0.0 3.6e-39 133.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase CBM_20 PF00686.19 GAM40083.1 - 8e-20 70.6 0.2 1.7e-19 69.5 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain Gal_mutarotas_2 PF13802.6 GAM40083.1 - 6e-10 39.3 1.2 2e-09 37.6 1.2 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like MFS_1 PF07690.16 GAM40084.1 - 5.9e-08 32.0 37.8 1.1e-07 31.1 37.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAM40084.1 - 1.1e-06 28.5 8.6 1.3e-06 28.3 6.1 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Fungal_trans PF04082.18 GAM40085.1 - 8.2e-05 21.8 0.0 0.00016 20.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40085.1 - 0.00031 20.8 7.2 0.00069 19.7 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 GAM40086.1 - 2.8e-18 66.4 0.0 4.5e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM40086.1 - 5.5e-16 59.0 0.0 1.2e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM40086.1 - 0.0018 17.8 0.1 0.0056 16.2 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 GAM40086.1 - 0.012 15.7 0.1 0.27 11.4 0.0 2.7 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 GAM40086.1 - 0.021 14.9 0.0 0.073 13.1 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase KR PF08659.10 GAM40086.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 GAM40086.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAM40086.1 - 0.16 11.0 0.0 0.43 9.7 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein USP8_dimer PF08969.11 GAM40086.1 - 0.18 12.0 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 USP8 dimerisation domain Transferase PF02458.15 GAM40087.1 - 3e-11 42.6 0.0 5.6e-11 41.7 0.0 1.3 1 1 0 1 1 1 1 Transferase family HTH_Tnp_Mu_1 PF02316.16 GAM40087.1 - 0.035 14.3 0.0 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 Mu DNA-binding domain CDCA PF18484.1 GAM40087.1 - 0.2 11.5 0.0 1.8 8.4 0.0 2.0 2 0 0 2 2 2 0 Cadmium carbonic anhydrase repeat Peptidase_M13_N PF05649.13 GAM40088.1 - 2.7e-90 303.8 0.0 4.6e-90 303.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 GAM40088.1 - 9.4e-63 211.5 0.0 1.7e-62 210.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 RasGEF PF00617.19 GAM40089.1 - 6.3e-44 150.3 0.4 1.2e-43 149.3 0.4 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM40089.1 - 4.1e-13 49.5 0.1 1.9e-12 47.3 0.1 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif Crystallin PF00525.18 GAM40089.1 - 0.25 11.5 3.3 7.1 6.9 0.1 3.3 3 0 0 3 3 3 0 Alpha crystallin A chain, N terminal DIL PF01843.19 GAM40090.1 - 1.2e-29 102.6 1.8 1.2e-29 102.6 1.8 1.9 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 GAM40090.1 - 2.4e-14 53.6 0.1 8e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM40090.1 - 2.8e-10 40.3 0.0 0.0003 21.0 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM40090.1 - 3e-08 34.0 0.0 9.2e-05 22.9 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM40090.1 - 6.4e-08 32.7 0.1 0.012 16.1 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 GAM40090.1 - 1.9e-06 27.8 1.1 0.0064 16.9 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat MFS_1 PF07690.16 GAM40091.1 - 5.9e-33 114.3 61.1 5.9e-33 114.3 61.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM40091.1 - 0.00054 18.5 32.6 0.0011 17.5 32.5 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Orf78 PF06024.12 GAM40091.1 - 0.29 11.4 1.8 1.7 9.0 0.0 2.8 2 1 1 3 3 3 0 Orf78 (ac78) 4HBT_2 PF13279.6 GAM40092.1 - 5.7e-10 39.7 0.0 1e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily WBS_methylT PF12589.8 GAM40092.1 - 0.042 14.6 0.5 0.082 13.7 0.5 1.4 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome ELO PF01151.18 GAM40093.1 - 8.1e-63 212.3 14.2 9.9e-63 212.0 14.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family p450 PF00067.22 GAM40094.1 - 9.5e-84 281.8 0.0 1.1e-83 281.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RabGAP-TBC PF00566.18 GAM40095.1 - 3.3e-34 118.4 0.0 5.2e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mo25 PF08569.11 GAM40096.1 - 7.5e-126 419.9 0.0 8.4e-126 419.8 0.0 1.0 1 0 0 1 1 1 1 Mo25-like Methyltransf_25 PF13649.6 GAM40097.1 - 5.4e-11 43.0 0.3 2e-10 41.2 0.0 2.2 3 0 0 3 3 1 1 Methyltransferase domain PrmA PF06325.13 GAM40097.1 - 6.8e-11 42.1 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 GAM40097.1 - 1.8e-09 38.1 0.0 8.7e-09 35.9 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM40097.1 - 2.7e-08 33.7 0.0 7.1e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cir_N PF10197.9 GAM40097.1 - 1.5e-06 28.3 4.5 1.5e-06 28.3 4.5 4.3 4 0 0 4 4 2 1 N-terminal domain of CBF1 interacting co-repressor CIR Methyltransf_18 PF12847.7 GAM40097.1 - 3.2e-06 27.1 0.4 9.3e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAM40097.1 - 7.3e-06 25.6 0.1 1.3e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 GAM40097.1 - 9.6e-06 25.5 0.0 7.1e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM40097.1 - 0.0027 18.4 0.1 0.011 16.5 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM40097.1 - 0.0032 16.9 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 GAM40097.1 - 0.0048 15.9 0.0 0.01 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 GAM40097.1 - 0.0053 16.5 0.0 0.0096 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 GAM40097.1 - 0.0074 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain UPF0020 PF01170.18 GAM40097.1 - 0.015 15.0 0.1 0.06 13.0 0.0 2.0 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 CMAS PF02353.20 GAM40097.1 - 0.031 13.6 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TehB PF03848.14 GAM40097.1 - 0.039 13.4 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 GAM40097.1 - 0.042 13.6 0.2 0.18 11.5 0.0 2.1 3 0 0 3 3 3 0 Lysine methyltransferase PRMT5 PF05185.16 GAM40097.1 - 0.14 12.0 0.1 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase KxDL PF10241.9 GAM40098.1 - 4.9e-31 106.8 0.1 6.6e-31 106.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein But2 PF09792.9 GAM40099.1 - 3.6e-59 199.2 6.1 8.8e-59 198.0 6.1 1.7 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain ADH_zinc_N PF00107.26 GAM40100.1 - 6.7e-18 64.9 0.0 6.5e-17 61.7 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM40100.1 - 5.3e-14 53.4 0.0 8e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM40100.1 - 0.011 15.6 0.7 2 8.3 0.1 2.8 1 1 2 3 3 3 0 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 GAM40101.1 - 1e-26 93.7 26.8 1e-26 93.7 26.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.22 GAM40101.1 - 0.00022 20.4 8.6 0.00022 20.4 8.6 2.6 2 1 0 2 2 2 1 Acyltransferase family Methyltransf_31 PF13847.6 GAM40102.1 - 1.7e-27 96.1 0.0 2.3e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM40102.1 - 1.6e-23 83.2 0.1 3e-23 82.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM40102.1 - 3.1e-23 82.3 0.1 6.5e-23 81.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM40102.1 - 1.1e-17 64.2 0.0 1.9e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAM40102.1 - 1.5e-15 57.7 0.0 2.6e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM40102.1 - 1.2e-12 47.9 0.0 2e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 GAM40102.1 - 1.2e-11 44.6 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 GAM40102.1 - 7.7e-08 32.3 0.0 1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 GAM40102.1 - 3.1e-07 30.1 0.0 4.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 GAM40102.1 - 6.3e-07 29.0 0.0 1.4e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.11 GAM40102.1 - 2.7e-06 26.6 0.1 7.6e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) GidB PF02527.15 GAM40102.1 - 5.9e-05 22.5 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G NodS PF05401.11 GAM40102.1 - 8.2e-05 22.3 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.12 GAM40102.1 - 0.0003 20.0 0.0 0.00045 19.4 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase TehB PF03848.14 GAM40102.1 - 0.00041 19.8 0.0 0.0006 19.3 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 GAM40102.1 - 0.0014 18.5 0.0 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase RrnaAD PF00398.20 GAM40102.1 - 0.0018 17.4 0.0 0.0024 17.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.7 GAM40102.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 GAM40102.1 - 0.026 13.8 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 GAM40102.1 - 0.059 13.4 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain V_cholerae_RfbT PF05575.11 GAM40102.1 - 0.08 12.2 0.0 3.5 6.8 0.0 2.1 1 1 1 2 2 2 0 Vibrio cholerae RfbT protein UPF0020 PF01170.18 GAM40102.1 - 0.16 11.6 0.1 1.3 8.7 0.1 2.0 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 FAD_binding_4 PF01565.23 GAM40103.1 - 2e-19 69.7 2.7 4.1e-19 68.7 2.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM40103.1 - 2.4e-06 27.5 0.0 7.1e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like Sec62 PF03839.16 GAM40104.1 - 3.3 7.2 6.1 0.23 10.9 0.7 1.8 2 0 0 2 2 2 0 Translocation protein Sec62 CcmH PF03918.14 GAM40105.1 - 0.056 12.7 0.3 0.11 11.8 0.3 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein ATP_transf PF09830.9 GAM40106.1 - 3.6e-17 62.3 0.0 8.5e-17 61.1 0.0 1.7 2 0 0 2 2 2 1 ATP adenylyltransferase FAD_binding_4 PF01565.23 GAM40107.1 - 1.5e-23 83.1 2.6 2.6e-23 82.3 2.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM40107.1 - 4.9e-07 29.8 0.0 1.3e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like TauD PF02668.16 GAM40108.1 - 6.3e-36 124.5 0.0 8.8e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 GAM40108.1 - 0.039 13.1 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 CsiD TilS PF09179.11 GAM40108.1 - 0.22 12.1 1.2 5.7 7.5 0.2 2.7 3 0 0 3 3 3 0 TilS substrate binding domain Dala_Dala_lig_C PF07478.13 GAM40109.1 - 1.5e-11 44.2 0.0 2.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 GAM40109.1 - 5.7e-05 23.2 0.0 8.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 GAM40109.1 - 0.00032 20.3 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 GAM40109.1 - 0.00059 19.5 0.0 0.0039 16.8 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 GAM40109.1 - 0.00094 19.0 0.0 0.0021 17.9 0.0 1.5 1 1 1 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 GAM40109.1 - 0.041 13.5 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain BATS PF06968.13 GAM40110.1 - 3.9e-22 78.2 0.1 1.2e-21 76.6 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 GAM40110.1 - 4e-15 56.6 0.0 1.5e-14 54.7 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Aminotran_1_2 PF00155.21 GAM40111.1 - 5.9e-40 137.6 0.0 6.9e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAM40111.1 - 0.00064 18.4 0.0 0.00097 17.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme FERM_f0 PF16511.5 GAM40111.1 - 0.033 14.5 0.0 0.07 13.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM OKR_DC_1 PF01276.20 GAM40111.1 - 0.038 12.7 0.0 0.082 11.6 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain ResIII PF04851.15 GAM40111.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Aminotran_3 PF00202.21 GAM40112.1 - 4.4e-38 131.0 0.0 1.6e-18 66.5 0.0 3.1 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.6 GAM40112.1 - 4.7e-22 78.8 0.0 8.6e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC2_membrane PF01061.24 GAM40113.1 - 4.8e-80 267.9 45.8 1.1e-41 142.5 18.2 3.5 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 GAM40113.1 - 5.4e-34 117.6 0.0 5.5e-17 62.6 0.0 3.7 3 1 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 GAM40113.1 - 3.8e-29 100.4 11.2 9.2e-28 96.0 0.1 3.9 4 0 0 4 4 4 2 CDR ABC transporter Sugar_tr PF00083.24 GAM40113.1 - 9.7e-16 57.7 2.9 9.7e-16 57.7 2.9 3.0 4 0 0 4 4 3 1 Sugar (and other) transporter ABC_trans_N PF14510.6 GAM40113.1 - 3.7e-13 49.9 0.1 8.6e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal MFS_1 PF07690.16 GAM40113.1 - 1.7e-10 40.4 4.0 1.7e-10 40.4 4.0 4.1 4 1 0 4 4 3 1 Major Facilitator Superfamily AAA_25 PF13481.6 GAM40113.1 - 2.2e-07 30.6 0.0 2.2e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM40113.1 - 5.5e-06 26.9 0.1 0.032 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAM40113.1 - 1.3e-05 25.2 0.0 0.0029 17.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 GAM40113.1 - 0.00019 21.3 0.0 0.4 10.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM40113.1 - 0.00028 20.6 1.5 0.05 13.4 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 GAM40113.1 - 0.0003 20.3 0.0 0.086 12.3 0.0 3.6 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 GAM40113.1 - 0.00056 20.5 0.0 0.077 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 GAM40113.1 - 0.0011 19.4 0.0 1.9 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GAM40113.1 - 0.0028 17.8 0.4 0.46 10.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 GAM40113.1 - 0.0038 16.8 0.3 0.36 10.4 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 GAM40113.1 - 0.0057 16.9 0.4 2.7 8.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAM40113.1 - 0.0058 16.4 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAM40113.1 - 0.011 15.7 0.7 1.8 8.4 0.2 2.8 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 GAM40113.1 - 0.028 14.9 0.1 6.5 7.2 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAM40113.1 - 0.06 13.6 0.4 4.6 7.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAM40113.1 - 0.096 13.1 0.0 22 5.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 GAM40113.1 - 0.28 11.7 0.6 2.8 8.4 0.3 2.2 2 0 0 2 2 2 0 AAA domain TRI12 PF06609.13 GAM40113.1 - 0.28 9.5 5.4 0.094 11.1 1.4 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) ABC2_membrane_3 PF12698.7 GAM40113.1 - 0.57 9.2 36.0 0.2 10.8 11.9 2.7 2 0 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 GAM40113.1 - 3.1 7.0 15.1 0.69 9.1 4.6 2.7 2 0 0 2 2 2 0 ABC-2 family transporter protein HD PF01966.22 GAM40114.1 - 1.7e-07 31.5 0.0 2.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 GAM40114.1 - 0.0051 16.3 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 HDOD domain HD_6 PF18019.1 GAM40114.1 - 0.038 14.1 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 HD domain adh_short PF00106.25 GAM40115.1 - 2e-45 154.6 0.0 3.7e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40115.1 - 2.5e-45 154.9 0.0 4e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pollen_allerg_1 PF01357.21 GAM40115.1 - 7.2e-16 58.0 0.1 1.5e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 Pollen allergen KR PF08659.10 GAM40115.1 - 1e-08 35.3 0.0 1.6e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 KR domain DPBB_1 PF03330.18 GAM40115.1 - 5.3e-05 23.4 0.0 0.00014 22.1 0.0 1.7 1 0 0 1 1 1 1 Lytic transglycolase DUF1776 PF08643.10 GAM40115.1 - 0.042 13.2 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FGGY_C PF02782.16 GAM40117.1 - 9.8e-74 247.4 0.3 1.7e-73 246.6 0.3 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GAM40117.1 - 7e-70 235.4 0.0 9.1e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 GAM40117.1 - 0.03 13.8 0.3 5.7 6.3 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MIP PF00230.20 GAM40118.1 - 2.4e-52 177.9 4.4 4.3e-52 177.1 4.4 1.4 1 0 0 1 1 1 1 Major intrinsic protein DAO PF01266.24 GAM40118.1 - 1.9e-46 159.3 1.0 4.9e-30 105.3 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase DAO_C PF16901.5 GAM40118.1 - 2.7e-40 137.2 0.0 5.4e-40 136.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_oxidored PF12831.7 GAM40118.1 - 3.3e-07 30.0 1.0 4.8e-07 29.5 1.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM40118.1 - 8.1e-06 25.2 3.7 0.00095 18.3 0.7 2.2 1 1 1 2 2 2 2 FAD binding domain GIDA PF01134.22 GAM40118.1 - 3.9e-05 22.9 0.4 7.7e-05 21.9 0.4 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 GAM40118.1 - 4.2e-05 22.9 0.9 0.00013 21.3 0.9 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM40118.1 - 0.0029 16.7 0.1 0.0049 16.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAM40118.1 - 0.0031 17.7 1.3 0.068 13.4 0.6 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAM40118.1 - 0.008 15.5 0.1 1.1 8.4 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 GAM40118.1 - 0.061 12.6 0.0 0.42 9.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM40118.1 - 0.088 13.4 0.2 0.25 11.9 0.1 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM40118.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 GAM40118.1 - 0.22 11.4 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 GAM40118.1 - 0.24 10.5 0.0 13 4.8 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Fungal_trans PF04082.18 GAM40119.1 - 2.6e-28 98.8 0.6 4e-28 98.2 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40119.1 - 1.6e-06 28.1 10.7 1.6e-06 28.1 10.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI PF01437.25 GAM40119.1 - 0.099 13.2 3.4 0.29 11.7 3.4 1.8 1 0 0 1 1 1 0 Plexin repeat Ank_2 PF12796.7 GAM40120.1 - 7.5e-30 103.4 5.6 5.4e-09 36.5 0.0 6.6 4 1 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM40120.1 - 5e-27 93.9 13.5 1.5e-05 25.4 0.1 7.7 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 GAM40120.1 - 2.1e-25 88.0 18.2 0.0001 22.6 0.0 10.2 8 2 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 GAM40120.1 - 4.6e-24 81.9 13.4 0.0021 18.4 0.0 11.4 12 1 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.6 GAM40120.1 - 8.7e-23 80.1 10.6 6.7e-08 32.7 0.2 7.7 7 1 1 8 8 8 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM40121.1 - 7.9e-13 48.8 0.1 2.4e-10 40.8 0.0 3.5 3 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM40121.1 - 5.8e-12 45.9 2.8 2.3e-07 31.2 0.1 4.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) NACHT PF05729.12 GAM40121.1 - 6.2e-11 42.5 0.1 8.5e-10 38.8 0.0 2.6 2 1 0 2 2 2 1 NACHT domain Ank_3 PF13606.6 GAM40121.1 - 3.5e-09 36.1 0.2 6.7e-05 23.0 0.1 4.1 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAM40121.1 - 3.8e-09 36.6 4.7 0.00013 22.2 0.2 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAM40121.1 - 1.3e-05 25.4 0.9 0.007 16.7 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 GAM40121.1 - 0.00013 22.4 0.0 0.00038 20.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 GAM40121.1 - 0.00078 19.9 0.0 0.0038 17.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Helo_like_N PF17111.5 GAM40121.1 - 0.0042 16.5 0.5 0.013 14.8 0.1 2.0 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 GAM40121.1 - 0.0051 17.1 0.0 0.019 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAM40121.1 - 0.014 15.7 0.0 0.056 13.8 0.0 2.0 2 1 0 2 2 2 0 RNA helicase Glyco_hydro_25 PF01183.20 GAM40121.1 - 0.05 13.8 0.0 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 25 NB-ARC PF00931.22 GAM40121.1 - 0.063 12.5 0.0 0.2 10.8 0.0 1.9 1 1 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 GAM40121.1 - 0.087 12.4 0.1 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF1187 PF06688.11 GAM40121.1 - 0.15 12.5 0.6 5.5 7.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1187) DUF2075 PF09848.9 GAM40121.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Abhydrolase_6 PF12697.7 GAM40122.1 - 2.9e-18 67.3 1.3 3.4e-18 67.0 1.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM40122.1 - 0.00021 21.0 0.1 0.00038 20.2 0.1 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM40122.1 - 0.082 12.2 0.0 0.91 8.7 0.0 2.4 4 0 0 4 4 4 0 Serine aminopeptidase, S33 Methyltransf_25 PF13649.6 GAM40123.1 - 2.5e-10 40.9 0.0 6.5e-09 36.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM40123.1 - 4.6e-09 36.3 0.0 7.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM40123.1 - 3.6e-08 34.0 0.0 1.5e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM40123.1 - 2.5e-05 24.1 0.0 6.4e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM40123.1 - 7.5e-05 23.3 0.0 0.00024 21.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain TPMT PF05724.11 GAM40123.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_2 PF00891.18 GAM40123.1 - 0.075 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 GAM40123.1 - 0.19 11.2 0.0 0.65 9.4 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase ketoacyl-synt PF00109.26 GAM40124.1 - 2e-35 122.6 0.0 1.2e-34 120.0 0.0 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAM40124.1 - 3.8e-30 104.3 0.0 8.6e-30 103.2 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAM40124.1 - 1.2e-07 32.2 0.0 2.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension FAD_binding_4 PF01565.23 GAM40125.1 - 3.8e-24 85.0 0.2 6e-23 81.1 0.4 2.2 2 0 0 2 2 2 1 FAD binding domain His_Phos_1 PF00300.22 GAM40126.1 - 3.2e-18 66.1 0.0 3.1e-10 40.1 0.0 2.0 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) adh_short PF00106.25 GAM40127.1 - 2.3e-39 134.9 0.0 3e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40127.1 - 4.1e-27 95.3 0.0 5.5e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40127.1 - 1.6e-16 60.7 0.0 2.2e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM40127.1 - 0.00016 21.3 0.0 0.00057 19.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pneumo_M2 PF07380.11 GAM40127.1 - 0.0059 16.8 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 Pneumovirus M2 protein Polysacc_synt_2 PF02719.15 GAM40127.1 - 0.013 14.6 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Peptidase_S10 PF00450.22 GAM40128.1 - 6.1e-105 352.0 8.8 7.4e-105 351.8 8.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase adh_short PF00106.25 GAM40129.1 - 5.2e-20 71.7 0.0 9.6e-16 57.8 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40129.1 - 1.6e-08 34.4 0.0 4.5e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40129.1 - 1.8e-05 24.8 0.0 3.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM40129.1 - 0.00067 18.9 0.0 0.00097 18.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAM40129.1 - 0.0009 18.8 0.0 0.0021 17.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAM40129.1 - 0.0018 17.5 0.0 0.0043 16.3 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 GAM40129.1 - 0.0082 15.6 0.1 0.019 14.4 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 GAM40129.1 - 0.036 14.1 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.18 GAM40130.1 - 6.2e-16 58.2 0.7 1.1e-15 57.5 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40130.1 - 4.6e-06 26.7 14.9 8.4e-06 25.8 14.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 GAM40132.1 - 1e-101 340.7 11.5 4.3e-100 335.4 11.5 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Beta-lactamase PF00144.24 GAM40133.1 - 3e-37 128.6 0.0 5.4e-37 127.8 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase Amidohydro_2 PF04909.14 GAM40133.1 - 2.9e-21 76.5 0.0 4.5e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Wbp11 PF09429.10 GAM40133.1 - 0.061 13.7 0.3 5.7 7.4 0.0 2.7 3 0 0 3 3 3 0 WW domain binding protein 11 adh_short PF00106.25 GAM40134.1 - 1.1e-33 116.3 0.0 1.5e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40134.1 - 1.5e-20 73.8 0.0 2.1e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 GAM40134.1 - 0.002 18.1 0.2 0.0062 16.5 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KR PF08659.10 GAM40134.1 - 0.0027 17.6 0.0 0.04 13.8 0.0 2.0 2 0 0 2 2 2 1 KR domain K-cyclin_vir_C PF09080.10 GAM40134.1 - 0.098 13.1 0.2 0.44 11.0 0.1 1.9 2 0 0 2 2 2 0 K cyclin, C terminal RPE65 PF03055.15 GAM40135.1 - 4.2e-109 365.8 0.0 4.7e-109 365.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SnoaL_4 PF13577.6 GAM40136.1 - 2e-05 24.7 0.3 3.3e-05 24.0 0.3 1.4 1 0 0 1 1 1 1 SnoaL-like domain Glyco_hydro_106 PF17132.4 GAM40137.1 - 1.5e-16 59.9 0.1 2.3e-16 59.3 0.1 1.2 1 0 0 1 1 1 1 alpha-L-rhamnosidase AAA_18 PF13238.6 GAM40138.1 - 5.4e-24 85.2 0.0 1.2e-23 84.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 GAM40138.1 - 9.9e-06 26.0 0.0 3.6e-05 24.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 GAM40138.1 - 0.00053 20.4 0.0 0.0037 17.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAM40138.1 - 0.0022 18.2 0.0 0.013 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 GAM40138.1 - 0.013 15.6 0.0 0.05 13.7 0.0 1.9 2 0 0 2 2 2 0 Adenylate kinase AAA_28 PF13521.6 GAM40138.1 - 0.016 15.5 0.0 0.047 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAM40138.1 - 0.027 14.8 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 GAM40138.1 - 0.072 13.0 0.3 0.13 12.1 0.1 1.5 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.6 GAM40138.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAM40138.1 - 0.11 12.8 0.1 0.2 11.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 GAM40138.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Ham1p_like PF01725.16 GAM40139.1 - 2.4e-58 197.1 0.0 2.7e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF1918 PF08940.11 GAM40139.1 - 0.018 14.7 0.1 0.067 12.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Glyco_hydro_42 PF02449.15 GAM40139.1 - 0.12 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase Myosin_head PF00063.21 GAM40140.1 - 1.5e-263 876.1 2.7 2.6e-263 875.3 2.7 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 GAM40140.1 - 1.5e-26 92.7 2.5 1.5e-26 92.7 2.5 2.8 2 1 0 2 2 2 1 DIL domain IQ PF00612.27 GAM40140.1 - 2.3e-16 58.0 27.0 5.2e-05 22.7 2.0 5.8 5 0 0 5 5 5 4 IQ calmodulin-binding motif Myosin_N PF02736.19 GAM40140.1 - 3.9e-05 23.4 0.9 0.0001 22.0 0.9 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain GAS PF13851.6 GAM40140.1 - 8.7e-05 22.0 14.7 8.7e-05 22.0 14.7 3.2 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding AAA_16 PF13191.6 GAM40140.1 - 0.0015 19.0 0.7 0.01 16.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAM40140.1 - 0.0053 16.7 0.0 0.021 14.8 0.0 2.1 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 GAM40140.1 - 0.012 15.8 0.8 0.04 14.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAM40140.1 - 0.15 12.4 0.1 1 9.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Phage_GP20 PF06810.11 GAM40140.1 - 0.29 10.9 11.0 13 5.6 9.8 2.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 ATG16 PF08614.11 GAM40140.1 - 0.31 11.2 31.6 4.3 7.5 31.7 2.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 GAM40140.1 - 0.93 9.3 29.7 0.035 13.9 7.9 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH FUSC PF04632.12 GAM40140.1 - 2.8 6.4 4.2 4.4 5.7 4.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4615 PF15393.6 GAM40140.1 - 3.8 8.1 9.5 50 4.4 9.5 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) APG6_N PF17675.1 GAM40140.1 - 5 7.7 37.5 1.7 9.1 23.7 3.6 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF484 PF04340.12 GAM40140.1 - 5.8 6.5 9.4 21 4.7 9.4 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF484 DegQ PF08181.11 GAM40140.1 - 6.7 6.9 9.6 0.39 10.8 2.0 2.9 2 0 0 2 2 2 0 DegQ (SacQ) family DUF4665 PF15679.5 GAM40140.1 - 7.2 7.3 6.3 4.2 8.1 1.4 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4665) NAP PF00956.18 GAM40141.1 - 4.9e-100 334.2 7.9 4.9e-100 334.2 7.9 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) P5-ATPase PF12409.8 GAM40142.1 - 6e-37 126.5 0.0 1.4e-36 125.3 0.0 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 GAM40142.1 - 4.6e-32 111.0 0.6 1.5e-31 109.3 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAM40142.1 - 2.8e-17 63.7 0.0 1.5e-08 35.2 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM40142.1 - 0.0021 17.7 0.0 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAM40142.1 - 0.003 17.6 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAM40142.1 - 0.011 15.5 0.0 4.1 7.1 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 GAM40143.1 - 4.6e-63 213.0 0.0 5.6e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM40143.1 - 3.4e-31 108.5 0.0 4.5e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 GAM40143.1 - 0.00075 19.2 0.0 0.98 9.0 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 GAM40143.1 - 0.0018 17.7 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAM40143.1 - 0.015 14.3 0.0 0.033 13.1 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 GAM40143.1 - 0.084 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase 2-Hacid_dh_C PF02826.19 GAM40144.1 - 8.6e-47 158.8 0.0 1.6e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAM40144.1 - 4.9e-36 123.3 0.1 7.7e-36 122.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAM40144.1 - 0.00036 20.8 0.1 0.0011 19.2 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 GAM40144.1 - 0.00036 20.2 0.0 0.00094 18.9 0.0 1.8 1 0 0 1 1 1 1 ACT domain IlvN PF07991.12 GAM40144.1 - 0.019 14.6 0.2 1.5 8.4 0.0 2.7 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 GAM40144.1 - 0.024 15.1 0.5 0.26 11.8 0.0 2.4 2 1 0 2 2 2 0 XdhC Rossmann domain tRNA-synt_2b PF00587.25 GAM40145.1 - 8.3e-39 133.4 0.0 1.3e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 GAM40145.1 - 7.6e-16 58.3 7.0 7.6e-16 58.3 7.0 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain RF-1 PF00472.20 GAM40145.1 - 0.055 13.4 3.8 0.13 12.2 3.8 1.5 1 0 0 1 1 1 0 RF-1 domain Cytochrom_C552 PF02335.15 GAM40145.1 - 0.082 11.8 7.6 0.86 8.5 0.2 2.2 2 0 0 2 2 2 0 Cytochrome c552 Ras PF00071.22 GAM40146.1 - 5.5e-45 152.9 0.2 7e-45 152.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM40146.1 - 1.4e-15 57.6 0.1 2e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM40146.1 - 2.7e-07 30.2 0.0 3.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM40146.1 - 0.0001 22.4 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM40146.1 - 0.00022 20.8 0.6 0.0026 17.3 0.2 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAM40146.1 - 0.0021 17.5 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit HNH_2 PF13391.6 GAM40146.1 - 0.0029 17.7 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease RsgA_GTPase PF03193.16 GAM40146.1 - 0.0046 16.9 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 GAM40146.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAM40146.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 GAM40146.1 - 0.094 12.2 0.0 0.44 10.1 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B WAPL PF07814.13 GAM40147.1 - 1.5e-68 231.3 4.3 2e-68 230.9 4.3 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.6 GAM40148.1 - 6.1e-79 264.3 0.0 7.5e-79 264.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 GAM40148.1 - 0.0074 15.8 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 GAM40148.1 - 0.23 11.4 0.2 0.36 10.8 0.2 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.13 GAM40149.1 - 4.1e-29 100.5 0.1 5.1e-29 100.1 0.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 GAM40149.1 - 0.013 15.5 0.8 0.43 10.7 0.2 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 GAM40149.1 - 0.021 14.2 0.1 0.043 13.2 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribosomal_S3Ae PF01015.18 GAM40150.1 - 3.5e-88 294.5 2.3 4.4e-88 294.1 2.3 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 GAM40150.1 - 0.011 16.3 0.0 0.096 13.2 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 GAM40150.1 - 0.14 12.2 0.3 0.84 9.7 0.0 2.2 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Peptidase_C78 PF07910.13 GAM40151.1 - 6.1e-69 231.7 0.0 8.4e-69 231.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.12 GAM40151.1 - 0.00029 21.1 5.1 0.021 15.1 1.1 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 GAM40151.1 - 0.0027 17.2 1.1 0.014 15.0 0.1 2.6 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-TRAF PF02176.18 GAM40151.1 - 0.2 12.4 1.3 0.46 11.2 0.1 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger AA_kinase PF00696.28 GAM40152.1 - 2.1e-39 135.5 0.2 3.3e-39 134.9 0.2 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 GAM40152.1 - 7.5e-14 51.3 1.3 1.8e-11 43.6 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 GAM40152.1 - 2.1e-11 43.4 1.5 6.4e-09 35.4 0.1 3.2 3 0 0 3 3 3 2 ACT domain Forkhead PF00250.18 GAM40153.1 - 1.6e-35 121.2 0.0 2.8e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain G10 PF01125.17 GAM40154.1 - 2.1e-41 141.1 1.0 2.5e-41 140.9 1.0 1.0 1 0 0 1 1 1 1 G10 protein Ribosomal_L23eN PF03939.13 GAM40155.1 - 3.1e-24 84.9 7.4 3.1e-24 84.9 7.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 GAM40155.1 - 2.3e-16 59.9 1.5 3.8e-16 59.2 1.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 PHA-1 PF06542.11 GAM40155.1 - 0.063 12.1 0.3 0.079 11.8 0.3 1.1 1 0 0 1 1 1 0 Regulator protein PHA-1 Bmt2 PF11968.8 GAM40156.1 - 1.8e-87 292.8 0.0 2.2e-87 292.5 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 DUF1161 PF06649.12 GAM40156.1 - 0.17 12.1 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Aa_trans PF01490.18 GAM40157.1 - 4e-66 223.4 23.6 4.7e-66 223.2 23.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MerC PF03203.14 GAM40157.1 - 0.0082 16.6 3.5 0.0082 16.6 3.5 2.6 2 1 1 3 3 3 1 MerC mercury resistance protein Phage_holin_2_3 PF16080.5 GAM40157.1 - 7.2 6.5 10.1 0.23 11.2 0.6 3.1 3 0 0 3 3 3 0 Bacteriophage holin family HP1 eRF1_2 PF03464.15 GAM40158.1 - 6.2e-47 159.2 0.1 1.1e-46 158.5 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GAM40158.1 - 1.4e-38 131.8 0.6 3.1e-38 130.7 0.6 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 GAM40158.1 - 1.2e-21 77.1 0.0 2e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 GAM40158.1 - 1.1e-08 35.4 0.0 2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 GAM40158.1 - 5e-08 33.3 0.1 8.4e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor PDT PF00800.18 GAM40159.1 - 1.7e-59 200.7 0.3 3e-59 199.9 0.3 1.4 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 GAM40159.1 - 3e-06 26.9 0.0 7.3e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 ACT domain UPF0253 PF06786.12 GAM40159.1 - 0.081 13.2 0.1 3.9 7.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) DER1 PF04511.15 GAM40160.1 - 1e-15 58.2 0.9 1.7e-15 57.4 0.9 1.3 1 0 0 1 1 1 1 Der1-like family MaoC_dehydratas PF01575.19 GAM40160.1 - 0.00012 21.6 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain NapD PF03927.13 GAM40160.1 - 0.17 12.0 0.2 0.36 10.9 0.2 1.5 1 0 0 1 1 1 0 NapD protein DKCLD PF08068.12 GAM40161.1 - 1e-33 115.2 0.1 3e-32 110.4 0.1 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 GAM40161.1 - 2.5e-23 83.1 0.1 1.9e-20 73.7 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 GAM40161.1 - 3.6e-23 81.5 1.7 6.6e-23 80.6 1.7 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 GAM40161.1 - 7.1e-22 77.2 1.6 1.3e-21 76.4 1.6 1.4 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 GAM40161.1 - 0.0057 16.9 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain Med19 PF10278.9 GAM40161.1 - 4 7.3 19.9 7.5 6.5 19.9 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CLTH PF10607.9 GAM40163.1 - 2.6e-35 121.5 0.1 5.2e-35 120.5 0.1 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 GAM40163.1 - 0.0037 17.2 0.0 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 LisH DUF2203 PF09969.9 GAM40163.1 - 0.058 14.1 2.2 3.6 8.3 0.7 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) COX16 PF14138.6 GAM40163.1 - 0.27 11.8 1.6 0.65 10.6 1.6 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DMAP1 PF05499.12 GAM40163.1 - 0.31 10.9 6.7 0.12 12.3 2.2 2.4 3 0 0 3 3 3 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF2431 PF10354.9 GAM40164.1 - 7e-63 211.9 0.0 1.2e-62 211.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) eIF-3c_N PF05470.12 GAM40164.1 - 0.99 7.6 12.7 0.28 9.5 4.6 2.8 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus EamA PF00892.20 GAM40165.1 - 4.7e-06 26.8 9.6 4.7e-06 26.8 9.6 2.2 2 0 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 GAM40165.1 - 0.016 14.6 18.3 0.21 10.9 18.3 2.1 1 1 0 1 1 1 0 Triose-phosphate Transporter family UPF0370 PF13980.6 GAM40165.1 - 0.14 12.2 0.2 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) Ycf66_N PF07444.11 GAM40165.1 - 0.29 11.3 6.1 0.61 10.3 1.4 3.2 3 0 0 3 3 3 0 Ycf66 protein N-terminus Thioredoxin PF00085.20 GAM40166.1 - 0.00079 19.4 0.0 0.0015 18.5 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin SMI1_KNR4 PF09346.10 GAM40167.1 - 6.6e-34 117.2 0.0 1.7e-33 115.8 0.0 1.7 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) PNRC PF15365.6 GAM40168.1 - 1e-08 34.7 8.7 1e-08 34.7 8.7 3.3 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif zf-rbx1 PF12678.7 GAM40169.1 - 3.8e-25 87.9 12.8 5.6e-25 87.4 12.8 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAM40169.1 - 3.6e-17 62.2 10.0 4.7e-17 61.8 10.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 GAM40169.1 - 2.8e-06 27.5 14.8 0.0001 22.6 14.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM40169.1 - 9.4e-05 22.2 3.7 9.4e-05 22.2 3.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM40169.1 - 0.0016 18.3 11.9 0.028 14.3 11.9 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GAM40169.1 - 0.2 11.8 9.1 0.88 9.8 9.2 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 GAM40169.1 - 0.28 11.1 10.6 0.67 9.9 4.3 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAM40169.1 - 0.64 9.7 14.6 0.11 12.1 4.6 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 GAM40169.1 - 0.64 10.1 8.3 2.5 8.2 8.3 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 GAM40169.1 - 1.1 9.1 17.1 99 2.8 17.1 2.5 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 GAM40169.1 - 9.2 6.3 11.4 51 3.9 11.4 2.3 1 1 0 1 1 1 0 zinc-RING finger domain SPC12 PF06645.13 GAM40170.1 - 1.3e-30 105.3 0.8 1.5e-30 105.0 0.8 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ZYG-11_interact PF05884.12 GAM40170.1 - 0.002 17.6 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Interactor of ZYG-11 MerC PF03203.14 GAM40170.1 - 0.062 13.8 0.1 0.064 13.7 0.1 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein DUF3040 PF11239.8 GAM40170.1 - 0.14 12.5 0.7 0.19 12.0 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Es2 PF09751.9 GAM40171.1 - 2.6e-135 452.5 11.0 3.1e-135 452.3 11.0 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 PBD PF00786.28 GAM40172.1 - 0.079 13.3 0.1 0.25 11.7 0.1 1.9 1 0 0 1 1 1 0 P21-Rho-binding domain Anillin_N PF16018.5 GAM40172.1 - 4.2 8.0 0.0 4.2 8.0 0.0 4.4 5 1 0 5 5 5 0 Anillin N-terminus Mid1 PF12929.7 GAM40173.1 - 1.9e-158 528.2 13.7 2.5e-158 527.8 13.7 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component CorA PF01544.18 GAM40173.1 - 4.8e-37 127.9 0.0 8.8e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Fz PF01392.22 GAM40173.1 - 0.0067 17.0 7.1 0.057 14.1 2.7 2.7 2 0 0 2 2 2 1 Fz domain GHMP_kinases_N PF00288.26 GAM40174.1 - 4.8e-10 39.5 0.0 1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAM40174.1 - 0.0003 21.1 0.0 0.00058 20.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal TPR_2 PF07719.17 GAM40175.1 - 9e-31 103.5 33.0 0.0018 18.3 0.0 12.5 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 GAM40175.1 - 5.3e-27 92.5 27.2 4.7e-06 26.2 0.1 11.1 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 GAM40175.1 - 6.1e-24 84.3 29.3 8.2e-05 23.0 0.1 10.9 8 4 2 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 GAM40175.1 - 1.6e-22 77.7 20.4 0.002 18.2 0.3 11.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAM40175.1 - 1.4e-17 62.8 25.2 0.13 13.1 0.0 12.8 10 2 2 12 12 12 6 Tetratricopeptide repeat TPR_12 PF13424.6 GAM40175.1 - 9.6e-14 51.4 23.5 0.0062 16.8 0.0 9.9 9 2 1 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAM40175.1 - 9.9e-13 47.8 23.8 0.043 14.5 0.1 12.3 14 0 0 14 14 12 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM40175.1 - 5.1e-12 46.2 25.6 6.1e-05 23.6 0.1 9.2 8 2 1 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAM40175.1 - 1.2e-09 37.5 19.3 0.003 17.5 0.2 8.7 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAM40175.1 - 4.9e-08 32.8 4.0 1 9.9 0.0 7.8 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM40175.1 - 4.7e-07 29.5 33.1 0.0019 18.0 0.0 9.4 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM40175.1 - 2.8e-06 26.9 28.3 0.091 12.5 0.1 9.5 10 1 1 11 11 10 4 TPR repeat TPR_3 PF07720.12 GAM40175.1 - 0.00058 19.8 8.1 0.42 10.7 0.2 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAM40175.1 - 0.0026 18.2 8.8 0.084 13.5 0.2 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM40175.1 - 0.013 15.7 14.6 1.9 8.8 0.1 5.9 6 1 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TOM20_plant PF06552.12 GAM40175.1 - 0.38 10.5 3.5 1 9.0 0.0 3.3 2 1 2 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.6 GAM40175.1 - 0.95 9.6 12.9 4.2 7.5 0.2 5.3 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Acyltransferase PF01553.21 GAM40176.1 - 4e-27 94.5 0.0 6.1e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 GAM40176.1 - 6.2e-14 51.9 0.1 1.4e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus NAD_kinase PF01513.21 GAM40177.1 - 7.7e-49 166.5 0.0 1.1e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 GAM40177.1 - 0.011 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain RsgI_N PF12791.7 GAM40177.1 - 0.36 10.8 0.8 0.75 9.8 0.1 1.9 2 0 0 2 2 2 0 Anti-sigma factor N-terminus Pkinase PF00069.25 GAM40178.1 - 1e-67 228.3 0.8 1e-66 225.0 0.8 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM40178.1 - 5e-51 173.5 0.0 8.6e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 GAM40178.1 - 1.8e-24 85.9 0.4 1.8e-23 82.6 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.6 GAM40178.1 - 1.1e-13 51.6 0.2 2.9e-13 50.2 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 GAM40178.1 - 4.1e-06 27.3 0.2 1.1e-05 25.9 0.2 1.8 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 GAM40178.1 - 7.9e-06 25.4 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAM40178.1 - 3.9e-05 22.6 0.0 3.9e-05 22.6 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase Haspin_kinase PF12330.8 GAM40178.1 - 6.6e-05 22.0 0.3 0.00013 21.0 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 GAM40178.1 - 0.01 14.9 0.1 0.019 14.1 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 KIND PF16474.5 GAM40178.1 - 0.13 12.1 1.8 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Kinase non-catalytic C-lobe domain APH PF01636.23 GAM40178.1 - 1.4 8.7 5.4 0.39 10.6 0.2 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family DDRGK PF09756.9 GAM40178.1 - 9.6 5.7 16.4 0.83 9.2 9.2 2.2 2 0 0 2 2 2 0 DDRGK domain HGTP_anticodon PF03129.20 GAM40179.1 - 8.6e-20 70.7 0.0 8.6e-20 70.7 0.0 2.5 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAM40179.1 - 2.7e-08 34.0 0.0 8.8e-08 32.3 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) InPase PF18823.1 GAM40179.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Inorganic Pyrophosphatase Stk19 PF10494.9 GAM40179.1 - 0.14 11.8 1.2 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 Serine-threonine protein kinase 19 Brix PF04427.18 GAM40180.1 - 4.4e-24 85.7 0.2 6.7e-24 85.1 0.2 1.3 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 GAM40180.1 - 0.15 11.4 22.4 0.21 10.9 22.4 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 GAM40180.1 - 1.6 7.2 9.9 2.2 6.7 9.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 GAM40180.1 - 2.5 6.2 22.3 3.4 5.8 22.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3807 PF12720.7 GAM40180.1 - 2.9 8.2 21.0 0.62 10.3 11.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DNA_pol_phi PF04931.13 GAM40180.1 - 3 5.8 18.6 4.3 5.3 18.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 GAM40180.1 - 4.8 6.3 6.9 7.8 5.6 6.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit F-box-like PF12937.7 GAM40181.1 - 0.13 12.2 2.1 0.25 11.3 0.1 2.6 2 1 0 2 2 2 0 F-box-like PDR_CDR PF06422.12 GAM40182.1 - 1.5e-20 72.9 0.1 3.4e-20 71.7 0.1 1.6 1 0 0 1 1 1 1 CDR ABC transporter ABC_tran PF00005.27 GAM40182.1 - 3.4e-12 47.0 0.1 8.4e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 GAM40182.1 - 1.7e-10 40.7 5.9 1.7e-10 40.7 5.9 1.8 2 0 0 2 2 2 1 ABC-2 type transporter RsgA_GTPase PF03193.16 GAM40182.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase ABC_trans_N PF14510.6 GAM40182.1 - 0.0005 20.6 0.1 0.0018 18.8 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_18 PF13238.6 GAM40182.1 - 0.018 15.6 0.0 0.048 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAM40182.1 - 0.026 14.9 0.1 0.056 13.8 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 GAM40182.1 - 0.049 13.7 0.2 0.14 12.3 0.2 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 GAM40182.1 - 0.054 13.7 0.5 0.19 12.0 0.5 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAM40182.1 - 0.075 13.2 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAM40182.1 - 0.091 12.5 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAM40182.1 - 0.091 12.5 0.3 0.22 11.3 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 GAM40182.1 - 0.21 11.2 0.2 0.47 10.0 0.2 1.5 1 0 0 1 1 1 0 AAA domain NDT80_PhoG PF05224.12 GAM40183.1 - 1.1e-37 130.0 0.1 3.1e-37 128.6 0.0 1.8 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family MMPL PF03176.15 GAM40183.1 - 0.1 11.5 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 MMPL family Ribosomal_60s PF00428.19 GAM40183.1 - 2.4 8.8 16.2 0.14 12.7 3.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPD52 PF04201.15 GAM40184.1 - 0.079 12.6 0.6 0.24 11.0 0.3 1.8 2 0 0 2 2 2 0 Tumour protein D52 family Fungal_trans PF04082.18 GAM40185.1 - 1.3e-17 63.7 2.0 2.1e-17 63.0 2.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.21 GAM40186.1 - 2.3e-73 247.4 0.0 3.2e-73 246.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 GAM40186.1 - 4e-05 23.8 0.0 0.00012 22.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 GAM40186.1 - 0.00021 21.3 0.0 0.00046 20.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_6 PF13480.7 GAM40186.1 - 0.088 13.0 0.1 0.55 10.4 0.1 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Glucosamine_iso PF01182.20 GAM40187.1 - 7.1e-22 78.4 0.0 1e-21 77.9 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Aldedh PF00171.22 GAM40188.1 - 5.7e-158 526.2 0.7 6.9e-158 525.9 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 GAM40188.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 WTAP/Mum2p family GMC_oxred_N PF00732.19 GAM40189.1 - 2.3e-50 171.6 0.0 2.9e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM40189.1 - 2.9e-36 125.2 0.0 4.4e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 GAM40189.1 - 2.6e-05 24.4 0.1 0.00018 21.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM40189.1 - 5.2e-05 22.5 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 GAM40189.1 - 5.9e-05 22.3 0.0 8.6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAM40189.1 - 0.00043 19.6 0.0 0.0045 16.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM40189.1 - 0.00046 19.9 0.1 0.0037 16.9 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM40189.1 - 0.0039 17.7 0.2 1 10.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM40189.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 GAM40189.1 - 0.014 14.7 0.0 3.4 6.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 GAM40189.1 - 0.015 14.6 0.1 0.3 10.4 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 GAM40189.1 - 0.043 13.1 0.0 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Amidohydro_1 PF01979.20 GAM40190.1 - 8.1e-20 71.4 0.0 1.3e-19 70.7 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM40190.1 - 3.6e-13 49.8 0.5 9.6e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family UNC-93 PF05978.16 GAM40191.1 - 0.0081 15.9 4.4 0.0081 15.9 4.4 2.4 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 AMP-binding PF00501.28 GAM40192.1 - 7.7e-92 308.1 0.0 1e-91 307.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM40192.1 - 1.6e-11 45.0 0.2 2.8e-11 44.3 0.2 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Amidase PF01425.21 GAM40193.1 - 2.3e-36 125.7 4.8 8.6e-22 77.7 5.4 3.3 1 1 1 3 3 3 3 Amidase Fungal_trans PF04082.18 GAM40194.1 - 3.5e-33 114.8 0.7 5.7e-33 114.1 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40194.1 - 0.00081 19.5 17.2 0.0016 18.5 17.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 GAM40195.1 - 6.3e-12 45.4 0.5 5.1e-10 39.1 0.1 3.0 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 GAM40195.1 - 0.016 14.8 0.3 0.063 12.9 0.1 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM40195.1 - 0.019 14.2 0.4 4.9 6.3 0.0 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DegT_DnrJ_EryC1 PF01041.17 GAM40195.1 - 0.053 12.8 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_TACC PF12709.7 GAM40196.1 - 5.6e-11 42.7 23.3 1.1e-09 38.5 2.9 4.4 4 0 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins Tropomyosin_1 PF12718.7 GAM40196.1 - 0.6 10.3 37.7 0.77 9.9 23.0 3.6 2 1 1 3 3 3 0 Tropomyosin like QueH PF02677.14 GAM40196.1 - 0.78 9.8 3.3 2.1 8.4 3.3 1.8 1 0 0 1 1 1 0 Epoxyqueuosine reductase QueH ADIP PF11559.8 GAM40196.1 - 3.1 7.8 25.5 5.4 7.1 0.3 4.6 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding FlxA PF14282.6 GAM40196.1 - 3.6 7.6 9.9 1.8 8.6 1.4 3.4 2 1 0 2 2 2 0 FlxA-like protein CorA PF01544.18 GAM40196.1 - 5.3 6.3 5.4 0.71 9.1 0.7 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Z1 PF10593.9 GAM40196.1 - 8.7 5.8 8.3 10 5.6 0.5 2.7 2 1 0 2 2 2 0 Z1 domain DUF4407 PF14362.6 GAM40196.1 - 9.5 5.5 33.2 0.61 9.4 13.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) MFS_1 PF07690.16 GAM40197.1 - 4.7e-34 117.9 24.2 4.7e-34 117.9 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM40197.1 - 5.4e-10 38.7 2.4 5.4e-10 38.7 2.4 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 GAM40197.1 - 0.051 12.0 5.8 0.6 8.4 3.9 2.3 1 1 1 2 2 2 0 Transmembrane secretion effector MFS_1_like PF12832.7 GAM40197.1 - 0.95 8.3 13.9 0.17 10.7 3.3 2.8 3 0 0 3 3 3 0 MFS_1 like family DbpA PF03880.15 GAM40199.1 - 0.08 12.9 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 DbpA RNA binding domain Peptidase_S49_N PF08496.10 GAM40200.1 - 1.6 8.8 9.0 5.2 7.1 5.4 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Peptidase_S28 PF05577.12 GAM40201.1 - 2.2e-55 188.2 1.1 2.3e-42 145.3 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 CBM_3 PF00942.18 GAM40201.1 - 0.032 14.7 0.0 0.095 13.1 0.0 1.8 1 0 0 1 1 1 0 Cellulose binding domain Peptidase_S9 PF00326.21 GAM40201.1 - 0.048 13.1 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family CCD48 PF15799.5 GAM40202.1 - 0.0012 17.2 0.4 0.0022 16.4 0.4 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 SlyX PF04102.12 GAM40202.1 - 0.0054 17.3 4.2 0.91 10.2 1.1 2.4 2 0 0 2 2 2 2 SlyX PV-1 PF06637.11 GAM40202.1 - 0.007 15.2 0.1 0.013 14.4 0.1 1.3 1 0 0 1 1 1 1 PV-1 protein (PLVAP) DUF2046 PF09755.9 GAM40202.1 - 0.012 14.9 0.4 0.17 11.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF4763 PF15960.5 GAM40202.1 - 0.016 14.5 0.4 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) ATG16 PF08614.11 GAM40202.1 - 0.021 15.1 10.4 0.59 10.3 10.4 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 GAM40202.1 - 0.028 14.8 0.9 0.062 13.7 0.1 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) SOGA PF11365.8 GAM40202.1 - 0.036 15.2 2.1 0.11 13.7 0.4 2.1 2 0 0 2 2 2 0 Protein SOGA End3 PF12761.7 GAM40202.1 - 0.04 14.1 1.1 5.1 7.2 0.2 2.2 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Herpes_UL6 PF01763.16 GAM40202.1 - 0.085 11.4 0.1 0.64 8.5 0.1 1.9 2 0 0 2 2 2 0 Herpesvirus UL6 like DivIC PF04977.15 GAM40202.1 - 0.43 10.4 3.6 0.35 10.7 0.4 2.0 2 0 0 2 2 2 0 Septum formation initiator CCDC92 PF14916.6 GAM40202.1 - 0.67 9.8 2.5 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain of unknown function T7SS_ESX_EspC PF10824.8 GAM40202.1 - 0.69 10.4 3.7 0.95 10.0 0.4 2.3 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm DegS PF05384.11 GAM40202.1 - 0.82 9.1 4.3 0.4 10.2 1.2 1.8 2 0 0 2 2 2 0 Sensor protein DegS CCDC106 PF15794.5 GAM40202.1 - 2.4 7.8 10.6 8.8 6.0 0.3 2.1 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 106 RRM_1 PF00076.22 GAM40203.1 - 1.3e-08 34.5 0.9 3.5e-08 33.1 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM40203.1 - 2.5e-06 27.4 0.0 5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 GAM40203.1 - 0.038 14.0 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 RNA binding motif HD_assoc PF13286.6 GAM40203.1 - 0.07 13.7 0.9 0.18 12.4 0.1 2.0 2 0 0 2 2 2 0 Phosphohydrolase-associated domain DUF530 PF04409.12 GAM40203.1 - 0.077 11.3 0.1 0.13 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF530) IBN_N PF03810.19 GAM40205.1 - 1e-15 57.4 0.2 1.5e-13 50.4 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 GAM40205.1 - 2.3e-06 26.7 0.0 7.4e-06 25.0 0.0 2.0 1 0 0 1 1 1 1 Cse1 RTP1_C1 PF10363.9 GAM40205.1 - 0.0054 16.9 0.2 0.099 12.8 0.1 2.8 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 GAM40205.1 - 0.0063 16.9 1.0 2 8.8 0.0 3.6 2 1 1 3 3 3 1 HEAT repeats RIX1 PF08167.12 GAM40205.1 - 0.062 13.0 0.0 3.6 7.3 0.0 3.5 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis SapB_2 PF03489.17 GAM40205.1 - 0.097 12.8 0.6 2 8.6 0.0 3.3 3 0 0 3 3 3 0 Saposin-like type B, region 2 Xpo1 PF08389.12 GAM40205.1 - 0.17 11.9 0.7 7.5 6.6 0.0 3.6 3 0 0 3 3 3 0 Exportin 1-like protein DSHCT PF08148.12 GAM40206.1 - 5.1e-52 175.8 0.4 1.3e-51 174.6 0.4 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 GAM40206.1 - 9.7e-41 138.7 1.3 1.6e-40 138.0 0.0 2.0 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 GAM40206.1 - 2e-20 73.9 0.0 4.1e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 GAM40206.1 - 2.1e-18 66.7 0.0 5.5e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAM40206.1 - 4.7e-06 26.7 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAM40206.1 - 6.4e-06 26.5 0.0 2.5e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF2415 PF10313.9 GAM40207.1 - 1.3e-14 53.8 0.0 3.9e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) HSP70 PF00012.20 GAM40208.1 - 3.8e-266 884.0 17.0 4.4e-266 883.8 17.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAM40208.1 - 9.3e-15 54.3 7.6 3e-13 49.3 1.4 2.9 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 GAM40208.1 - 0.00042 20.1 0.0 0.0013 18.4 0.0 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 GAM40208.1 - 0.0021 17.3 2.2 0.026 13.7 0.1 2.8 2 1 1 3 3 3 1 StbA protein Toxin-deaminase PF14424.6 GAM40208.1 - 0.054 13.6 0.9 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases TetR_C_25 PF17933.1 GAM40208.1 - 0.15 12.4 0.1 35 4.8 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 GAM40209.1 - 2.7e-57 194.7 0.9 3.8e-57 194.2 0.9 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAM40209.1 - 2.1e-11 43.4 0.7 3.7e-11 42.6 0.7 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAM40209.1 - 4.2e-08 32.6 1.7 6.2e-08 32.0 1.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 GAM40209.1 - 1.9e-05 24.0 0.4 3.2e-05 23.2 0.4 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 GAM40209.1 - 0.0033 16.7 0.3 0.005 16.1 0.3 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NanE PF04131.14 GAM40209.1 - 0.079 12.1 0.0 0.18 10.9 0.0 1.6 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Transp_cyt_pur PF02133.15 GAM40210.1 - 1.3e-43 149.5 45.3 1.5e-43 149.2 45.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TPP_enzyme_C PF02775.21 GAM40211.1 - 9.3e-09 35.2 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain eIF3g PF12353.8 GAM40212.1 - 1.7e-45 154.4 3.0 2.5e-45 153.9 3.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 GAM40212.1 - 4.3e-17 61.7 0.0 6.9e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 GAM40212.1 - 0.021 15.2 0.2 0.048 14.0 0.2 1.5 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 RRM_occluded PF16842.5 GAM40212.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif ribosomal_L24 PF17136.4 GAM40212.1 - 2 8.9 8.0 0.16 12.4 1.0 2.5 2 1 1 3 3 3 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 NDT80_PhoG PF05224.12 GAM40213.1 - 9.3e-40 136.8 0.2 1.7e-39 136.0 0.2 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Abhydrolase_3 PF07859.13 GAM40214.1 - 1.3e-47 162.4 0.0 1.6e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAM40214.1 - 1.4e-05 24.2 0.3 5e-05 22.4 0.3 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 GAM40214.1 - 0.00023 20.1 0.0 0.00034 19.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 GAM40214.1 - 0.0012 18.4 0.1 0.0087 15.5 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAM40214.1 - 0.0042 17.7 3.7 0.0079 16.8 3.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 GAM40214.1 - 0.0086 14.8 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 GAM40214.1 - 0.013 15.1 0.0 0.085 12.4 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family AMP-binding PF00501.28 GAM40215.1 - 6.1e-77 259.0 0.1 6e-75 252.4 0.1 2.1 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM40215.1 - 7.1e-05 23.7 1.1 0.00029 21.7 0.7 2.3 1 1 1 2 2 2 1 AMP-binding enzyme C-terminal domain CdhD PF03599.16 GAM40215.1 - 0.083 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Methyltransf_16 PF10294.9 GAM40216.1 - 6.2e-13 48.9 0.0 1.4e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase SH3_19 PF18597.1 GAM40216.1 - 0.0089 15.8 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 2 Myosin X N-terminal SH3 domain Methyltransf_11 PF08241.12 GAM40216.1 - 0.084 13.5 0.0 2.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain CCDC-167 PF15188.6 GAM40217.1 - 4.6 7.7 6.6 8.7 6.8 6.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Pkinase PF00069.25 GAM40218.1 - 2.2e-38 132.2 0.0 3e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM40218.1 - 1.8e-24 86.4 0.0 2.5e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HeLo PF14479.6 GAM40219.1 - 0.00018 21.4 0.9 0.00036 20.4 0.9 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Ank_2 PF12796.7 GAM40220.1 - 3.4e-96 316.0 0.0 6.5e-16 58.7 0.5 8.7 2 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM40220.1 - 1.9e-68 218.2 0.0 0.00015 21.9 0.0 16.4 16 0 0 16 16 16 15 Ankyrin repeat Ank_4 PF13637.6 GAM40220.1 - 8.2e-61 201.6 0.4 8.5e-10 39.0 0.0 12.6 6 3 7 14 14 14 12 Ankyrin repeats (many copies) Ank PF00023.30 GAM40220.1 - 5.5e-52 172.0 1.1 0.00074 19.8 0.0 15.4 16 0 0 16 16 16 12 Ankyrin repeat Ank_5 PF13857.6 GAM40220.1 - 3.1e-49 164.4 4.2 6.2e-08 32.8 0.1 11.2 4 4 9 13 13 13 11 Ankyrin repeats (many copies) Pkinase PF00069.25 GAM40220.1 - 2.5e-32 112.3 0.0 3.9e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM40220.1 - 5.3e-17 61.9 0.0 9.2e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM40220.1 - 0.01 14.6 0.2 0.035 12.9 0.1 2.0 2 0 0 2 2 2 0 Fungal protein kinase VWA_3_C PF18571.1 GAM40220.1 - 0.68 9.9 2.9 8.6 6.3 0.0 3.9 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain adh_short PF00106.25 GAM40221.1 - 1.9e-23 82.9 0.1 2.6e-23 82.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40221.1 - 4.2e-09 36.3 0.0 5.8e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40221.1 - 9.6e-06 25.6 0.1 1.6e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM40221.1 - 0.0031 16.7 0.1 0.0043 16.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GATase_6 PF13522.6 GAM40221.1 - 0.026 14.7 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain Shikimate_DH PF01488.20 GAM40221.1 - 0.058 13.5 0.1 0.091 12.8 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1254 PF06863.12 GAM40221.1 - 0.089 12.9 0.1 0.61 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1254) NAD_binding_7 PF13241.6 GAM40221.1 - 0.09 13.2 0.1 4.1 7.9 0.1 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Pterin_bind PF00809.22 GAM40222.1 - 7.1e-78 261.6 0.2 8.7e-78 261.4 0.2 1.1 1 0 0 1 1 1 1 Pterin binding enzyme LBP_M PF17385.2 GAM40222.1 - 0.042 13.4 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase central domain ArfGap PF01412.18 GAM40223.1 - 1.7e-34 118.4 0.1 2.9e-34 117.7 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TIM21 PF08294.11 GAM40224.1 - 2.3e-42 144.3 0.0 3e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 GAM40224.1 - 4.7e-06 26.3 0.0 3.2e-05 23.7 0.0 2.1 2 1 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 CMD PF02627.20 GAM40225.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Mhr1 PF12829.7 GAM40225.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination tRNA_anti_2 PF13742.6 GAM40225.1 - 0.18 12.0 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain MR_MLE_C PF13378.6 GAM40226.1 - 6.7e-58 195.8 0.0 1.1e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 GAM40226.1 - 1.9e-06 28.1 0.0 3.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Peptidase_Prp PF04327.12 GAM40226.1 - 0.047 13.9 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 Cysteine protease Prp MAAL_C PF07476.11 GAM40226.1 - 0.099 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus PWI PF01480.17 GAM40227.1 - 2.9e-06 27.5 0.2 7.5e-06 26.2 0.2 1.7 1 0 0 1 1 1 1 PWI domain DUF4298 PF14131.6 GAM40227.1 - 0.16 11.9 1.0 0.32 11.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) PGI PF00342.19 GAM40228.1 - 3.9e-240 797.5 0.4 4.6e-240 797.3 0.4 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Ribosomal_S21 PF01165.20 GAM40230.1 - 9.4e-10 38.1 1.2 9.4e-10 38.1 1.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S21 LMP PF04778.12 GAM40230.1 - 0.21 11.5 0.1 0.21 11.5 0.1 1.9 3 0 0 3 3 3 0 LMP repeated region Rhodanese PF00581.20 GAM40231.1 - 3e-11 43.8 0.0 4e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_28 PF02636.17 GAM40232.1 - 3.1e-80 269.6 0.0 4e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase UPF0767 PF15990.5 GAM40233.1 - 9.3 6.5 6.9 3.5 7.9 0.4 3.1 3 0 0 3 3 3 0 UPF0767 family Aminotran_1_2 PF00155.21 GAM40234.1 - 1.3e-82 277.9 0.0 1.5e-82 277.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.9 GAM40235.1 - 2.8e-14 53.1 0.7 2.8e-14 53.1 0.7 3.3 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 GAM40235.1 - 7.5e-06 25.9 0.4 0.00011 22.1 0.0 2.6 2 0 0 2 2 2 1 SNARE domain BORCS6 PF10157.9 GAM40235.1 - 0.39 10.9 5.2 1.4 9.1 0.0 3.3 2 2 0 3 3 3 0 BLOC-1-related complex sub-unit 6 LPP PF04728.13 GAM40235.1 - 0.42 11.0 0.1 0.42 11.0 0.1 3.3 4 0 0 4 4 4 0 Lipoprotein leucine-zipper TPR_1 PF00515.28 GAM40236.1 - 2.6e-15 55.5 2.1 3.1e-07 29.9 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM40236.1 - 4.4e-15 54.5 1.1 1.5e-05 24.8 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAM40236.1 - 8.6e-10 38.8 0.1 5.2e-06 26.7 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM40236.1 - 1e-08 34.7 0.2 7.7e-05 22.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM40236.1 - 5.9e-07 29.1 0.4 0.00015 21.6 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAM40236.1 - 6.8e-07 28.9 0.7 3.1e-05 23.5 0.2 3.5 2 1 1 3 3 3 1 TPR repeat TPR_6 PF13174.6 GAM40236.1 - 1.1e-05 25.7 0.0 2.3 9.1 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM40236.1 - 0.00036 20.6 0.0 0.19 11.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM40236.1 - 0.0017 19.0 0.2 0.25 12.0 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat PB1 PF00564.24 GAM40236.1 - 0.0029 17.5 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_14 PF13428.6 GAM40236.1 - 0.0033 18.1 0.1 0.19 12.6 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAM40236.1 - 0.012 16.2 0.0 64 4.6 0.0 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM40236.1 - 0.014 15.2 0.6 2.6 8.0 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAM40236.1 - 0.083 13.3 0.1 0.87 10.1 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Sod_Cu PF00080.20 GAM40237.1 - 4.9e-10 39.7 0.0 8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 GAM40237.1 - 7.1e-10 39.2 0.0 1.4e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Pkinase PF00069.25 GAM40238.1 - 2.1e-55 187.9 0.0 3.5e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM40238.1 - 6.3e-27 94.5 0.0 8.9e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAM40238.1 - 0.0016 17.8 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAM40238.1 - 0.003 16.9 0.1 0.015 14.6 0.1 1.9 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 GAM40238.1 - 0.0044 16.6 0.0 0.0044 16.6 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 GAM40238.1 - 0.025 13.5 0.3 0.045 12.7 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 GAM40238.1 - 0.15 10.8 0.9 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 GAM40238.1 - 0.21 11.5 0.1 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family GMC_oxred_N PF00732.19 GAM40240.1 - 2.8e-56 191.1 0.0 3.8e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM40240.1 - 3.2e-32 112.0 0.0 5.9e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 GAM40240.1 - 0.00093 19.4 0.0 0.0029 17.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAM40240.1 - 0.035 13.2 0.1 0.079 12.0 0.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAM40240.1 - 0.047 12.8 1.4 0.15 11.1 0.9 1.9 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 GAM40240.1 - 0.071 12.3 0.9 0.16 11.2 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM40240.1 - 0.086 12.1 0.7 0.2 10.9 0.1 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 GAM40241.1 - 2.6e-58 198.0 13.5 4.3e-43 147.8 1.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM40241.1 - 3.1e-08 32.9 32.0 1e-06 27.9 31.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily MMR_HSR1 PF01926.23 GAM40241.1 - 5.5e-08 32.9 0.0 1.3e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAM40241.1 - 2e-06 28.0 0.3 0.028 14.5 0.1 2.5 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 GAM40241.1 - 0.00023 20.7 0.1 0.00082 18.9 0.0 2.0 3 0 0 3 3 3 1 Ferrous iron transport protein B AIG1 PF04548.16 GAM40241.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family MFS_2 PF13347.6 GAM40241.1 - 0.0053 15.4 12.3 0.092 11.3 2.8 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein RsgA_GTPase PF03193.16 GAM40241.1 - 0.0097 15.8 0.2 0.047 13.6 0.2 2.1 1 1 0 1 1 1 1 RsgA GTPase IIGP PF05049.13 GAM40241.1 - 0.012 14.8 0.0 0.053 12.6 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Gluconate_2-dh3 PF13618.6 GAM40241.1 - 0.019 15.2 0.2 0.043 14.0 0.2 1.6 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 AAA_22 PF13401.6 GAM40241.1 - 0.031 14.6 0.0 0.092 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 GAM40241.1 - 0.032 13.5 0.1 0.097 11.9 0.0 1.7 1 1 0 1 1 1 0 Septin ABC_tran PF00005.27 GAM40241.1 - 0.13 12.8 0.2 0.78 10.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 GAM40241.1 - 1.9 8.9 4.2 1.7 9.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain CENP-B_dimeris PF09026.10 GAM40241.1 - 3.6 8.0 5.7 2.1 8.8 2.3 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PhyH PF05721.13 GAM40242.1 - 1.3e-16 61.5 0.0 1.6e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CortBP2 PF09727.9 GAM40242.1 - 0.065 13.1 0.2 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 Cortactin-binding protein-2 Fungal_trans_2 PF11951.8 GAM40243.1 - 2.9e-45 154.8 3.6 3.7e-45 154.4 3.6 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cytochrom_C1 PF02167.15 GAM40243.1 - 0.13 12.0 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C1 family Glyco_hydro_18 PF00704.28 GAM40244.1 - 4.6e-14 52.9 0.0 8e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 UPF0146 PF03686.13 GAM40244.1 - 0.03 14.2 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) GhoS PF11080.8 GAM40244.1 - 0.081 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Endoribonuclease GhoS MFS_1 PF07690.16 GAM40245.1 - 5e-33 114.5 41.7 5e-33 114.5 41.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM40246.1 - 2.6e-80 270.5 20.6 3.1e-80 270.3 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM40246.1 - 5.8e-22 78.1 36.6 5.5e-19 68.3 26.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 GAM40247.1 - 4.9e-08 33.0 8.7 9.3e-08 32.1 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.18 GAM40248.1 - 5e-30 104.9 0.1 7.4e-30 104.3 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PhyH PF05721.13 GAM40248.1 - 0.054 13.7 0.0 0.092 13.0 0.0 1.3 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Methyltransf_23 PF13489.6 GAM40249.1 - 4e-06 26.8 0.0 6.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM40249.1 - 0.0015 19.2 0.0 0.0028 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM40249.1 - 0.0024 18.6 0.0 0.0039 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 GAM40249.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_11 PF08241.12 GAM40249.1 - 0.027 15.1 0.0 0.052 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HD PF01966.22 GAM40250.1 - 1.9e-07 31.3 0.1 2.5e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 HD domain AhpC-TSA_2 PF13911.6 GAM40251.1 - 3.8e-19 68.9 0.0 5.4e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 GAM40251.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA family RIH_assoc PF08454.11 GAM40252.1 - 0.018 14.9 0.4 0.16 11.9 0.0 2.7 3 0 0 3 3 3 0 RyR and IP3R Homology associated zf-RING_2 PF13639.6 GAM40253.1 - 5.6e-14 52.2 4.7 9.9e-14 51.4 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAM40253.1 - 3.4e-11 42.7 1.6 6.2e-11 41.8 1.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAM40253.1 - 2.7e-09 36.7 4.9 4.9e-09 35.9 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM40253.1 - 9.1e-09 35.1 2.1 1.7e-08 34.2 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAM40253.1 - 1.1e-06 28.9 7.4 4.8e-06 26.8 7.4 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAM40253.1 - 4.5e-06 26.5 1.5 8.2e-06 25.7 1.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAM40253.1 - 4.7e-06 26.4 6.0 5.9e-05 22.9 6.0 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GAM40253.1 - 1.8e-05 24.5 1.2 3.4e-05 23.6 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM40253.1 - 0.00021 21.2 6.1 0.0005 20.1 6.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GAM40253.1 - 0.00089 19.3 1.8 0.0019 18.2 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GAM40253.1 - 0.0016 18.2 3.4 0.003 17.3 3.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 GAM40253.1 - 0.049 13.8 4.7 0.1 12.8 4.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 GAM40253.1 - 0.065 12.9 1.2 0.13 11.9 1.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 GAM40253.1 - 0.081 13.2 1.0 0.16 12.3 1.0 1.5 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 GAM40253.1 - 0.17 11.8 3.9 0.13 12.2 1.6 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 GAM40253.1 - 0.67 10.2 3.9 13 6.1 4.3 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain MS_channel PF00924.18 GAM40254.1 - 2.3e-19 69.8 2.6 3.7e-19 69.1 2.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel LRR19-TM PF15176.6 GAM40254.1 - 0.0016 18.4 0.0 0.0085 16.1 0.0 2.2 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain EF-hand_1 PF00036.32 GAM40254.1 - 0.0081 15.6 0.1 0.023 14.2 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAM40254.1 - 0.0094 15.8 0.0 0.029 14.3 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 GAM40254.1 - 0.01 16.3 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 GAM40254.1 - 0.049 13.1 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 EF hand DUF2976 PF11190.8 GAM40254.1 - 0.096 12.5 1.0 4.4 7.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Mgm101p PF06420.12 GAM40255.1 - 1e-79 265.9 0.0 1.3e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 SOG2 PF10428.9 GAM40255.1 - 4.3 6.4 11.8 5.4 6.1 11.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein BPL_N PF09825.9 GAM40256.1 - 2.5e-150 500.8 0.1 3.1e-150 500.5 0.1 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 GAM40256.1 - 1.7e-24 86.2 0.0 3e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 GAM40256.1 - 7.4e-06 25.8 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain ThuA PF06283.11 GAM40256.1 - 0.033 14.4 0.0 0.073 13.3 0.0 1.6 1 0 0 1 1 1 0 Trehalose utilisation TANGO2 PF05742.12 GAM40257.1 - 1.3e-71 241.6 0.0 1.6e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Carb_anhydrase PF00194.21 GAM40258.1 - 1.6e-35 122.9 0.1 2.8e-35 122.1 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase MR_MLE_C PF13378.6 GAM40260.1 - 8.3e-15 54.9 0.2 1.4e-14 54.2 0.2 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 GAM40260.1 - 0.0014 18.8 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain UPF0193 PF05250.11 GAM40260.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) MFS_1 PF07690.16 GAM40261.1 - 3.7e-27 95.2 39.0 5.1e-27 94.7 39.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM40261.1 - 3.2e-05 23.4 7.3 3.2e-05 23.4 7.3 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MIF4G PF02854.19 GAM40262.1 - 3.4e-50 170.6 0.0 6e-50 169.8 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 GAM40262.1 - 1.6e-22 79.5 2.1 5.9e-22 77.6 2.1 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Usp PF00582.26 GAM40263.1 - 2.6e-22 79.9 0.0 4.7e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Universal stress protein family FAD_binding_3 PF01494.19 GAM40264.1 - 2.3e-41 142.2 0.0 3.6e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM40264.1 - 8.5e-06 25.9 0.1 2.8e-05 24.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAM40264.1 - 6.5e-05 21.8 0.0 0.0001 21.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAM40264.1 - 0.00026 20.3 0.0 0.0018 17.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM40264.1 - 0.0011 18.2 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 GAM40264.1 - 0.002 17.8 0.1 0.018 14.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM40264.1 - 0.0024 18.4 0.0 0.024 15.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM40264.1 - 0.0031 16.6 0.1 0.0048 16.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAM40264.1 - 0.0071 15.6 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 GAM40264.1 - 0.0074 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 GAM40264.1 - 0.018 14.4 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 GAM40264.1 - 0.021 14.1 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AbfS_sensor PF18225.1 GAM40264.1 - 0.058 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain 3HCDH_N PF02737.18 GAM40264.1 - 0.096 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dynamin_N PF00350.23 GAM40265.1 - 2e-32 112.6 0.2 4.2e-32 111.5 0.2 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 GAM40265.1 - 1.1e-07 31.4 0.0 2.2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Fungal_trans_2 PF11951.8 GAM40265.1 - 2.6e-07 29.8 1.4 4.9e-07 28.9 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MMR_HSR1 PF01926.23 GAM40265.1 - 3.8e-05 23.8 0.1 0.00016 21.7 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 GAM40265.1 - 0.051 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAM40265.1 - 0.096 12.4 0.0 0.25 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF1330 PF07045.11 GAM40266.1 - 0.002 18.5 0.0 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) EthD PF07110.11 GAM40266.1 - 0.061 14.5 0.0 0.12 13.5 0.0 1.5 1 0 0 1 1 1 0 EthD domain DIOX_N PF14226.6 GAM40267.1 - 1.5e-25 90.2 0.0 2.6e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM40267.1 - 3.9e-20 72.2 0.0 7.6e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CBM_4_9 PF02018.17 GAM40268.1 - 0.00013 22.3 5.1 0.00013 22.3 5.1 6.6 3 3 4 7 7 7 1 Carbohydrate binding domain Aldedh PF00171.22 GAM40269.1 - 4.4e-69 233.2 0.1 5.5e-69 232.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4381 PF14316.6 GAM40270.1 - 0.054 13.7 0.2 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TMEM154 PF15102.6 GAM40270.1 - 0.22 11.5 0.1 0.22 11.5 0.1 2.5 2 0 0 2 2 2 0 TMEM154 protein family EVI2A PF05399.11 GAM40270.1 - 0.58 9.7 0.0 0.58 9.7 0.0 2.5 3 0 0 3 3 3 0 Ectropic viral integration site 2A protein (EVI2A) MARVEL PF01284.23 GAM40270.1 - 3.2 7.8 5.6 6.8 6.7 5.6 1.7 1 1 0 1 1 1 0 Membrane-associating domain Pro_isomerase PF00160.21 GAM40271.1 - 1.1e-51 175.2 0.0 2.2e-51 174.3 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 GAM40271.1 - 2e-10 41.1 0.1 0.001 19.9 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAM40271.1 - 0.00041 19.4 0.2 0.012 14.6 0.1 2.2 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 GAM40271.1 - 0.019 15.2 0.0 1.6 9.1 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Cpn60_TCP1 PF00118.24 GAM40272.1 - 2.2e-142 475.2 12.8 2.5e-142 475.0 12.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 GAM40272.1 - 0.097 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Macoilin PF09726.9 GAM40273.1 - 0.00056 18.6 0.8 0.00074 18.2 0.8 1.1 1 0 0 1 1 1 1 Macoilin family Rax2 PF12768.7 GAM40273.1 - 0.0087 15.5 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity ASH PF15780.5 GAM40273.1 - 0.073 13.3 0.2 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin SKG6 PF08693.10 GAM40273.1 - 0.14 11.6 8.7 0.6 9.6 8.7 2.1 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Shisa PF13908.6 GAM40273.1 - 0.17 12.1 7.1 0.028 14.7 1.5 2.3 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator CHD5 PF04420.14 GAM40273.1 - 0.24 11.2 0.6 0.45 10.4 0.6 1.4 1 0 0 1 1 1 0 CHD5-like protein Herpes_capsid PF06112.11 GAM40273.1 - 0.26 11.3 20.4 0.61 10.1 20.4 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF2756 PF10956.8 GAM40273.1 - 2.5 8.7 18.7 0.037 14.5 8.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) CDH-cyt PF16010.5 GAM40274.1 - 1.3e-23 83.6 0.4 2.3e-23 82.8 0.4 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 GAM40274.1 - 1.2e-08 35.1 13.3 1.2e-08 35.1 13.3 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 GAM40274.1 - 1.4e-05 25.3 0.1 3.5e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 GAM40274.1 - 0.00025 20.8 7.6 0.00025 20.8 7.6 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF2427) DUF4191 PF13829.6 GAM40274.1 - 0.011 15.1 1.8 0.023 14.0 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) SOR PF07682.11 GAM40274.1 - 0.052 12.4 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Sulphur oxygenase reductase Frag1 PF10277.9 GAM40274.1 - 0.055 13.0 16.1 0.13 11.7 16.2 1.6 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF4079 PF13301.6 GAM40274.1 - 0.28 11.3 13.8 1.7 8.8 3.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) SLATT_6 PF18169.1 GAM40274.1 - 0.62 9.6 2.7 3.5 7.2 1.0 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 CobD_Cbib PF03186.13 GAM40274.1 - 1.1 8.4 5.8 1.7 7.8 5.1 1.6 1 1 0 1 1 1 0 CobD/Cbib protein 7TMR-DISM_7TM PF07695.11 GAM40274.1 - 3.9 7.3 20.5 4.1 7.2 5.6 2.3 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF1430 PF07242.11 GAM40274.1 - 4.7 7.5 10.3 41 4.5 8.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1430) FA_desaturase PF00487.24 GAM40275.1 - 3.5e-24 86.0 31.1 5.6e-24 85.3 31.1 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAM40275.1 - 4e-09 36.5 0.0 8.2e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABC_tran PF00005.27 GAM40278.1 - 1.4e-44 151.9 0.0 4.5e-25 88.8 0.0 3.0 3 1 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 GAM40278.1 - 3.8e-34 118.6 32.7 2e-26 93.2 11.0 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 GAM40278.1 - 6.4e-12 45.9 0.3 0.15 11.8 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM40278.1 - 1e-08 34.9 5.3 0.018 14.5 0.1 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAM40278.1 - 3.4e-08 34.1 0.1 0.0054 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAM40278.1 - 3.3e-06 27.4 1.6 0.11 12.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAM40278.1 - 1.4e-05 25.0 0.1 0.094 12.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 GAM40278.1 - 2.4e-05 24.4 0.0 0.011 15.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 GAM40278.1 - 3.5e-05 23.5 1.0 0.3 10.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAM40278.1 - 0.00014 21.9 0.0 0.26 11.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 GAM40278.1 - 0.00018 22.0 0.3 0.29 11.5 0.0 4.1 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAM40278.1 - 0.0002 21.1 0.0 0.042 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAM40278.1 - 0.00044 20.4 0.1 1.9 8.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 GAM40278.1 - 0.0016 18.4 0.2 0.5 10.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 GAM40278.1 - 0.0023 18.3 0.1 9.1 6.7 0.0 3.5 3 0 0 3 3 3 0 RNA helicase NB-ARC PF00931.22 GAM40278.1 - 0.0027 16.9 1.6 1.4 8.1 0.1 3.1 2 2 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 GAM40278.1 - 0.0034 17.0 0.0 0.34 10.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 GAM40278.1 - 0.0038 16.8 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 GAM40278.1 - 0.0044 16.8 0.0 2 8.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain PRK PF00485.18 GAM40278.1 - 0.011 15.5 0.1 0.029 14.1 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.6 GAM40278.1 - 0.018 15.3 0.1 5.4 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 GAM40278.1 - 0.02 15.0 1.7 1.6 8.8 0.1 2.9 3 0 0 3 3 2 0 Dynamin family AAA_18 PF13238.6 GAM40278.1 - 0.02 15.4 0.0 9.9 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 GAM40278.1 - 0.021 13.9 0.1 3 6.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP-synt_ab PF00006.25 GAM40278.1 - 0.027 14.1 1.3 5.1 6.7 0.6 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 GAM40278.1 - 0.038 13.9 0.2 0.5 10.2 0.0 2.6 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 GAM40278.1 - 0.038 14.5 5.8 3.8 8.0 0.1 3.3 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 GAM40278.1 - 0.042 13.6 0.1 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 GAM40278.1 - 0.099 11.9 0.0 9.5 5.4 0.0 2.5 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.15 GAM40278.1 - 0.11 12.4 2.2 18 5.2 0.0 3.2 3 0 0 3 3 3 0 NTPase Viral_helicase1 PF01443.18 GAM40278.1 - 0.11 12.2 0.1 6.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 GAM40278.1 - 0.15 12.0 3.7 17 5.4 0.1 4.3 4 1 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 GAM40278.1 - 0.18 11.5 0.1 19 4.8 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 GAM40278.1 - 0.21 11.2 2.3 5.2 6.6 0.5 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 GAM40278.1 - 0.21 11.5 1.9 1.1 9.1 0.0 2.8 4 0 0 4 4 3 0 Rad17 P-loop domain Roc PF08477.13 GAM40278.1 - 0.24 11.6 0.6 19 5.5 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 GAM40278.1 - 0.31 11.1 1.4 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain dNK PF01712.19 GAM40278.1 - 0.31 10.9 2.9 5.8 6.7 0.1 3.0 3 0 0 3 3 3 0 Deoxynucleoside kinase PGM_PMM_I PF02878.16 GAM40279.1 - 1.4e-30 105.8 0.2 2.8e-30 104.8 0.2 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 GAM40279.1 - 3.5e-21 75.8 0.1 9.2e-21 74.4 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 GAM40279.1 - 7.7e-14 51.9 0.0 1.7e-13 50.8 0.0 1.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 GAM40279.1 - 5.9e-05 23.2 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain BHD_3 PF10405.9 GAM40279.1 - 0.0067 16.8 0.0 0.022 15.1 0.0 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Pyr_redox_2 PF07992.14 GAM40280.1 - 7.1e-71 238.8 6.8 7.4e-71 238.8 5.9 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAM40280.1 - 9.3e-40 135.3 0.1 2.7e-39 133.8 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAM40280.1 - 2.6e-23 82.4 9.3 6e-22 78.0 0.5 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAM40280.1 - 5.2e-11 42.5 11.5 1.8e-09 37.4 0.4 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAM40280.1 - 6.5e-10 38.7 6.2 5.9e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM40280.1 - 2e-09 37.5 3.7 4.6e-05 23.6 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAM40280.1 - 2.6e-09 36.7 10.5 1.6e-07 30.8 4.5 2.8 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAM40280.1 - 4.3e-07 29.4 10.3 7.9e-07 28.5 2.7 2.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 GAM40280.1 - 7.1e-07 29.1 12.5 0.037 13.6 0.5 4.1 4 0 0 4 4 4 3 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM40280.1 - 8.8e-07 28.0 14.2 0.00071 18.4 1.6 4.1 4 0 0 4 4 4 3 HI0933-like protein K_oxygenase PF13434.6 GAM40280.1 - 1.4e-06 27.8 0.8 0.021 14.0 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 GAM40280.1 - 7.7e-06 25.3 7.3 0.0037 16.6 0.3 3.3 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GAM40280.1 - 1.7e-05 24.2 2.9 0.00031 20.1 0.1 2.4 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 GAM40280.1 - 2.1e-05 23.8 2.3 0.0013 17.8 0.1 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein THF_DHG_CYH_C PF02882.19 GAM40280.1 - 0.047 13.0 1.6 0.45 9.8 0.1 3.0 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 GAM40280.1 - 0.055 13.4 3.7 0.057 13.3 0.9 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 GAM40280.1 - 0.058 12.6 9.3 0.54 9.4 1.1 2.8 2 1 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 GAM40280.1 - 0.22 12.0 2.5 0.93 10.0 0.1 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 GAM40280.1 - 0.87 8.4 6.0 1.1 8.0 0.6 2.2 2 0 0 2 2 2 0 Tryptophan halogenase FMO-like PF00743.19 GAM40280.1 - 1.1 7.6 2.9 1.4 7.2 0.9 2.0 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Sugar_tr PF00083.24 GAM40281.1 - 2.5e-80 270.5 20.1 3.2e-80 270.2 20.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM40281.1 - 1.4e-14 53.8 49.7 6.2e-10 38.5 22.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 GAM40281.1 - 0.15 11.9 4.1 0.53 10.2 4.1 1.9 1 0 0 1 1 1 0 Glycine zipper 2TM domain Cu_amine_oxid PF01179.20 GAM40282.1 - 9.2e-163 541.9 0.1 1.1e-162 541.6 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 GAM40282.1 - 4.2e-06 27.1 0.0 1.1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 GAM40282.1 - 0.066 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain PAF PF15715.5 GAM40283.1 - 0.029 14.9 0.1 0.1 13.2 0.1 1.9 3 0 0 3 3 3 0 PCNA-associated factor histone like domain Amidase PF01425.21 GAM40285.1 - 3.9e-16 59.0 1.9 5e-13 48.8 2.0 2.3 2 0 0 2 2 2 2 Amidase Fungal_trans PF04082.18 GAM40285.1 - 5.2e-13 48.6 0.2 2e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40285.1 - 1.4e-05 25.1 10.0 2.3e-05 24.4 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERM PF00769.19 GAM40285.1 - 0.088 12.6 0.8 8.2 6.2 0.1 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF2039 PF10217.9 GAM40285.1 - 0.67 10.3 7.0 1.5 9.2 7.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) FAD_binding_4 PF01565.23 GAM40286.1 - 4.5e-23 81.5 1.1 1.1e-22 80.2 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain Fungal_trans_2 PF11951.8 GAM40287.1 - 2.1e-05 23.5 0.5 2.8e-05 23.1 0.5 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_3 PF09069.11 GAM40287.1 - 0.0071 16.7 0.1 0.013 15.8 0.1 1.4 1 0 0 1 1 1 1 EF-hand adh_short PF00106.25 GAM40288.1 - 1.1e-30 106.6 0.0 2.2e-30 105.6 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40288.1 - 3.3e-23 82.5 0.1 1.7e-22 80.2 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40288.1 - 2e-10 40.9 0.7 1.4e-08 34.9 0.7 2.2 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAM40288.1 - 1.9e-06 27.5 0.0 2.7e-06 27.0 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 GAM40288.1 - 3.4e-06 27.1 0.1 7.8e-06 25.9 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 GAM40288.1 - 2.3e-05 24.0 0.1 4.7e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM40288.1 - 0.016 14.4 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAM40288.1 - 0.036 13.2 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.15 GAM40288.1 - 0.043 13.6 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NmrA PF05368.13 GAM40288.1 - 0.046 13.3 0.1 0.079 12.5 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family TetR_C_34 PF17929.1 GAM40288.1 - 0.057 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NAD_binding_2 PF03446.15 GAM40288.1 - 0.11 12.6 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FMN_red PF03358.15 GAM40289.1 - 1.3e-10 41.2 0.0 1.6e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAM40289.1 - 3.9e-07 30.0 0.0 4.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 GAM40289.1 - 0.00016 21.9 0.1 0.012 15.8 0.1 2.2 1 1 1 2 2 2 1 Flavodoxin Flavodoxin_5 PF12724.7 GAM40289.1 - 0.065 13.5 0.0 0.48 10.7 0.0 2.0 1 1 1 2 2 2 0 Flavodoxin domain ADH_N PF08240.12 GAM40290.1 - 4.7e-07 29.7 0.0 7.9e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM40290.1 - 9.1e-07 28.9 2.2 1.6e-06 28.2 2.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 GAM40290.1 - 0.0019 18.0 0.2 0.0039 16.9 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 GAM40290.1 - 0.0043 16.6 0.2 0.0064 16.0 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 GAM40290.1 - 0.045 13.2 0.2 0.079 12.4 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Ocnus PF05005.15 GAM40290.1 - 0.19 11.8 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) adh_short_C2 PF13561.6 GAM40291.1 - 3.2e-56 190.5 0.0 3.9e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM40291.1 - 9.2e-50 168.8 0.0 1.2e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM40291.1 - 2.1e-10 40.8 0.0 3e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM40291.1 - 0.0025 17.3 0.0 0.023 14.2 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_trans_4_2 PF13477.6 GAM40291.1 - 0.047 13.7 0.0 5.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase 4-like GDP_Man_Dehyd PF16363.5 GAM40291.1 - 0.063 12.7 0.0 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase MIP PF00230.20 GAM40292.1 - 4.2e-31 108.4 10.0 5.6e-31 108.0 10.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein TPR_12 PF13424.6 GAM40293.1 - 6.8e-09 35.9 0.1 1.7e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM40293.1 - 3.6e-06 26.7 1.0 0.0009 19.0 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM40293.1 - 0.052 13.4 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3848 PF12959.7 GAM40293.1 - 0.086 12.9 1.4 23 5.2 0.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3848) TPR_12 PF13424.6 GAM40294.1 - 2.3e-66 220.0 31.7 1.4e-20 73.4 1.3 4.4 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 GAM40294.1 - 9.6e-55 181.1 12.3 6.7e-13 48.1 0.1 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAM40294.1 - 3.2e-15 55.0 11.5 0.00073 19.4 0.1 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAM40294.1 - 3.5e-14 51.9 13.1 0.001 18.8 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAM40294.1 - 1.4e-10 41.1 8.7 0.58 11.1 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM40294.1 - 2.7e-10 39.6 5.6 0.14 12.4 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM40294.1 - 9.3e-09 34.7 11.2 0.27 11.4 0.7 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM40294.1 - 2.8e-08 34.3 7.8 0.051 14.2 0.1 4.5 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAM40294.1 - 6.7e-06 26.2 0.0 35 5.4 0.1 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM40294.1 - 9.7e-05 21.9 4.3 0.00053 19.5 3.7 2.0 1 1 1 2 2 2 2 MalT-like TPR region DUF1925 PF09094.11 GAM40294.1 - 0.00049 20.4 1.0 13 6.1 0.0 4.6 3 1 1 4 4 4 0 Domain of unknown function (DUF1925) TPR_17 PF13431.6 GAM40294.1 - 0.0021 18.3 0.4 63 4.3 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM40294.1 - 0.0045 17.5 11.7 0.2 12.2 1.7 3.8 1 1 3 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 GAM40294.1 - 0.0074 16.7 0.0 0.043 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF676 PF05057.14 GAM40294.1 - 0.033 13.7 0.1 0.073 12.6 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 GAM40294.1 - 0.062 12.6 0.0 0.51 9.6 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 HHH_3 PF12836.7 GAM40294.1 - 0.095 13.0 0.0 39 4.6 0.0 3.5 3 0 0 3 3 3 0 Helix-hairpin-helix motif Abhydrolase_6 PF12697.7 GAM40294.1 - 0.12 13.0 0.0 0.63 10.6 0.0 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family ResIII PF04851.15 GAM40294.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3107 PF11305.8 GAM40294.1 - 0.19 12.0 0.1 11 6.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3107) NRBF2_MIT PF17169.4 GAM40294.1 - 1.9 8.8 7.7 1.7 8.9 0.1 3.5 4 1 0 4 4 2 0 MIT domain of nuclear receptor-binding factor 2 TPR_11 PF13414.6 GAM40294.1 - 2.8 7.7 9.5 43 3.9 0.9 4.6 5 0 0 5 5 5 0 TPR repeat Cys_Met_Meta_PP PF01053.20 GAM40295.1 - 4.4e-32 111.1 0.0 7.9e-31 106.9 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAM40295.1 - 4e-08 32.8 0.0 8.8e-08 31.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_3 PF00202.21 GAM40296.1 - 1.9e-87 293.5 0.0 2.4e-87 293.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF3224 PF11528.8 GAM40296.1 - 0.044 13.6 0.3 0.25 11.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3224) Lyase_aromatic PF00221.19 GAM40297.1 - 1.4e-152 508.7 3.8 1.7e-152 508.3 3.8 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase AMP-binding PF00501.28 GAM40297.1 - 0.0081 14.8 0.0 0.019 13.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 GAM40298.1 - 1.5e-61 208.2 0.0 2e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Methyltransf_25 PF13649.6 GAM40299.1 - 1.4e-10 41.8 0.2 2.2e-10 41.1 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM40299.1 - 2.5e-10 40.9 0.2 4.7e-10 40.0 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM40299.1 - 4.4e-08 33.1 0.0 6.3e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM40299.1 - 6.6e-08 32.6 0.0 8.5e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM40299.1 - 5e-07 30.4 0.1 7.6e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM40299.1 - 5.3e-05 22.7 0.0 7.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 GAM40299.1 - 0.00016 21.6 0.0 0.00095 19.1 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 GAM40299.1 - 0.009 15.6 0.1 0.012 15.2 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 GAM40299.1 - 0.013 15.0 0.1 0.052 13.1 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.6 GAM40299.1 - 0.061 13.3 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.28 GAM40300.1 - 6.5e-99 331.4 0.0 9.4e-99 330.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 GAM40300.1 - 2.3e-83 279.7 0.7 4.2e-83 278.8 0.7 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAM40300.1 - 3.8e-53 181.0 0.2 6.7e-53 180.3 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM40300.1 - 4.3e-43 146.1 0.5 9.7e-43 145.0 0.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 GAM40300.1 - 1.5e-21 76.5 0.9 1.6e-09 38.0 0.2 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 GAM40300.1 - 2.4e-16 60.2 0.0 6.8e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension AMP-binding_C PF13193.6 GAM40300.1 - 2.9e-10 41.0 0.2 0.00051 21.0 0.0 3.2 3 0 0 3 3 2 2 AMP-binding enzyme C-terminal domain Methyltransf_25 PF13649.6 GAM40300.1 - 9.8e-09 35.8 0.0 6.1e-08 33.3 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM40300.1 - 6.6e-08 33.1 0.0 3.7e-07 30.7 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM40300.1 - 3e-07 31.1 0.0 2.3e-06 28.3 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain 4HBT PF03061.22 GAM40300.1 - 5.1e-05 23.6 0.1 0.00016 21.9 0.1 2.0 1 0 0 1 1 1 1 Thioesterase superfamily Thiolase_N PF00108.23 GAM40300.1 - 0.00041 19.8 0.3 0.00085 18.8 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.6 GAM40300.1 - 0.0015 18.4 0.0 0.0047 16.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Acyl-ACP_TE PF01643.17 GAM40300.1 - 0.027 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Acyl-ACP thioesterase NodS PF05401.11 GAM40300.1 - 0.027 14.1 0.0 0.077 12.6 0.0 1.7 1 0 0 1 1 1 0 Nodulation protein S (NodS) CBP PF12192.8 GAM40300.1 - 5.1 7.4 5.5 1.2 9.4 0.2 2.7 2 0 0 2 2 2 0 Fungal calcium binding protein ATPgrasp_N PF18130.1 GAM40301.1 - 1.5e-13 51.1 0.0 3.2e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 GAM40301.1 - 6.6e-10 38.8 0.0 2e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 GAM40301.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAM40301.1 - 0.061 12.8 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ABC_membrane PF00664.23 GAM40302.1 - 3.7e-99 331.8 40.0 5.7e-51 173.8 17.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM40302.1 - 1.6e-70 236.0 0.1 1.8e-34 119.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAM40302.1 - 9.4e-15 54.6 0.3 0.0011 18.4 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAM40302.1 - 2.1e-09 37.6 0.2 0.002 17.9 0.0 2.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 GAM40302.1 - 5.4e-09 36.7 2.7 0.0018 18.7 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 GAM40302.1 - 3.1e-06 26.8 0.1 0.026 14.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 GAM40302.1 - 3.3e-06 26.2 0.2 0.012 14.5 0.1 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 GAM40302.1 - 5.6e-06 26.4 0.0 0.075 12.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 GAM40302.1 - 1.8e-05 25.0 1.0 0.39 11.0 0.2 3.6 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 GAM40302.1 - 4.8e-05 23.4 0.0 0.067 13.2 0.0 3.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 GAM40302.1 - 5.6e-05 23.6 3.2 0.27 11.7 1.3 4.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 GAM40302.1 - 0.00031 20.6 0.1 1.1 9.0 0.0 2.9 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 GAM40302.1 - 0.00032 20.5 0.9 1.1 9.0 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAM40302.1 - 0.00069 19.2 0.0 0.41 10.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 GAM40302.1 - 0.00087 19.8 0.1 2.4 8.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAM40302.1 - 0.0016 19.0 0.0 1.3 9.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAM40302.1 - 0.0017 18.0 0.0 1.1 8.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 GAM40302.1 - 0.0046 17.2 4.7 3.5 7.9 0.1 4.2 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 GAM40302.1 - 0.0053 16.9 0.0 4.2 7.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAM40302.1 - 0.0055 16.0 0.7 1 8.6 0.0 3.0 4 0 0 4 4 3 1 Zeta toxin SRP54 PF00448.22 GAM40302.1 - 0.0062 16.2 0.1 1.7 8.2 0.0 3.3 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 GAM40302.1 - 0.01 15.6 0.7 6.4 6.5 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 GAM40302.1 - 0.014 15.1 0.1 7.3 6.2 0.0 2.8 3 1 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 GAM40302.1 - 0.018 15.3 0.2 2.3 8.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 GAM40302.1 - 0.02 13.9 0.0 0.14 11.1 0.0 2.2 3 0 0 3 3 2 0 Protein of unknown function (DUF3987) PRK PF00485.18 GAM40302.1 - 0.023 14.4 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 GAM40302.1 - 0.024 14.6 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain G-alpha PF00503.20 GAM40302.1 - 0.028 13.6 0.0 7 5.7 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit DUF87 PF01935.17 GAM40302.1 - 0.033 14.3 0.1 0.8 9.8 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 GAM40302.1 - 0.044 14.2 0.0 9.1 6.7 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 GAM40302.1 - 0.044 14.0 0.0 19 5.5 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 GAM40302.1 - 0.046 13.8 0.6 1.8 8.6 0.0 3.2 4 0 0 4 4 3 0 Dynamin family MMR_HSR1 PF01926.23 GAM40302.1 - 0.054 13.6 0.1 4.4 7.4 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 GAM40302.1 - 0.07 13.2 0.1 6 6.9 0.0 3.3 4 0 0 4 4 3 0 AAA domain Mg_chelatase PF01078.21 GAM40302.1 - 0.076 12.4 0.0 3.5 7.0 0.0 2.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 GAM40302.1 - 0.077 12.9 0.2 8.9 6.2 0.1 2.8 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 GAM40302.1 - 0.085 12.6 0.1 15 5.3 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TniB PF05621.11 GAM40302.1 - 0.11 11.9 0.0 16 4.8 0.0 3.0 3 1 0 4 4 4 0 Bacterial TniB protein AAA_24 PF13479.6 GAM40302.1 - 0.13 11.9 0.0 4.4 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Carn_acyltransf PF00755.20 GAM40303.1 - 1.1e-201 671.6 0.4 1.2e-201 671.4 0.4 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase FMO-like PF00743.19 GAM40304.1 - 8.6e-16 57.4 0.1 1.4e-12 46.8 0.0 3.0 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAM40304.1 - 1.2e-12 47.7 0.0 3.4e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM40304.1 - 3.2e-11 43.0 0.4 9e-10 38.2 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAM40304.1 - 3.3e-11 43.0 0.4 1e-10 41.4 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM40304.1 - 5e-07 29.9 0.0 2.4e-05 24.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAM40304.1 - 4.8e-05 22.7 0.3 0.00099 18.4 0.1 2.4 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 GAM40304.1 - 0.00023 21.7 0.0 0.1 13.2 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM40304.1 - 0.00025 20.2 0.0 13 4.7 0.0 4.0 4 0 0 4 4 4 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 GAM40304.1 - 0.0045 17.0 1.6 27 4.7 0.1 4.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding Mqo PF06039.15 GAM40304.1 - 0.03 12.9 0.1 1.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_7 PF13241.6 GAM40304.1 - 0.046 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 GAM40304.1 - 0.054 12.6 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 GAM40304.1 - 0.07 12.4 0.3 7.7 5.7 0.0 2.9 4 0 0 4 4 4 0 FAD binding domain Shikimate_DH PF01488.20 GAM40304.1 - 0.083 13.0 0.1 0.48 10.5 0.0 2.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NADHdh_A3 PF14987.6 GAM40304.1 - 0.12 12.7 0.2 0.86 10.0 0.2 2.2 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 DAO PF01266.24 GAM40304.1 - 0.17 11.4 6.1 1 8.9 0.3 3.7 2 1 1 4 4 4 0 FAD dependent oxidoreductase Abhydrolase_3 PF07859.13 GAM40305.1 - 1.3e-19 70.9 0.0 1.8e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAM40305.1 - 6.5e-15 54.9 0.0 1.2e-14 54.0 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase DUF2974 PF11187.8 GAM40305.1 - 0.043 13.4 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Epimerase PF01370.21 GAM40306.1 - 1.2e-15 57.6 0.0 1.9e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM40306.1 - 2e-13 50.0 0.0 2.8e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM40306.1 - 4.5e-10 39.4 0.0 4.4e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAM40306.1 - 2.4e-07 30.6 0.0 2.9e-05 23.7 0.1 2.5 2 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 GAM40306.1 - 2.9e-07 30.5 0.2 1.6e-06 28.1 0.2 2.1 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 GAM40306.1 - 1.8e-06 27.4 0.0 2.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 GAM40306.1 - 0.0036 17.2 0.1 0.019 14.9 0.1 2.0 2 0 0 2 2 2 1 KR domain DUF3425 PF11905.8 GAM40307.1 - 1.5e-20 73.4 0.0 2.4e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Spt20 PF12090.8 GAM40308.1 - 3 7.4 20.2 6.3 6.3 20.2 1.4 1 0 0 1 1 1 0 Spt20 family MFS_1 PF07690.16 GAM40309.1 - 3.8e-46 157.6 46.8 3.8e-46 157.6 46.8 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM40309.1 - 9.8e-13 47.4 26.8 2.2e-12 46.2 26.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 GAM40309.1 - 0.00045 18.6 3.8 0.00045 18.6 3.8 2.6 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family zf-LITAF-like PF10601.9 GAM40309.1 - 0.63 10.3 3.1 23 5.4 0.1 3.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain adh_short PF00106.25 GAM40310.1 - 9.2e-23 80.7 0.1 1.4e-22 80.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40310.1 - 1.2e-17 64.2 0.0 2.1e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Abhydrolase_6 PF12697.7 GAM40310.1 - 1.2e-13 52.2 0.1 1.7e-13 51.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family KR PF08659.10 GAM40310.1 - 2.9e-09 37.1 0.1 5.3e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 KR domain Abhydrolase_5 PF12695.7 GAM40310.1 - 0.013 15.2 0.0 0.051 13.3 0.0 2.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family Epimerase PF01370.21 GAM40310.1 - 0.091 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Oxidored_FMN PF00724.20 GAM40311.1 - 1.3e-38 133.2 0.0 1.8e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family adh_short PF00106.25 GAM40312.1 - 3.4e-36 124.6 0.0 4.8e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40312.1 - 3.3e-26 92.3 0.1 2e-24 86.4 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40312.1 - 1.4e-11 44.6 0.0 2.1e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DFP PF04127.15 GAM40312.1 - 0.2 11.5 0.3 0.45 10.3 0.2 1.6 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Glyco_hydro_16 PF00722.21 GAM40313.1 - 5.2e-41 140.1 5.2 5.2e-41 140.1 5.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF4148 PF13663.6 GAM40313.1 - 2.2 8.5 4.7 26 5.1 0.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) PepSY_2 PF13670.6 GAM40313.1 - 2.7 8.1 4.3 21 5.2 1.5 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Pkinase PF00069.25 GAM40314.1 - 2.7e-73 246.6 0.0 3.7e-73 246.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM40314.1 - 2.4e-36 125.3 0.0 3.8e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 GAM40314.1 - 9.5e-18 64.8 0.0 1e-10 42.1 0.0 2.5 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 GAM40314.1 - 7.5e-15 54.8 0.1 1.7e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 GAM40314.1 - 1.3e-05 24.6 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 GAM40314.1 - 0.00031 20.4 0.1 0.00068 19.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 GAM40314.1 - 0.0064 15.5 0.2 0.013 14.5 0.2 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAM40314.1 - 0.025 14.5 1.4 0.042 13.8 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 GAM40314.1 - 0.029 13.7 0.0 0.062 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 GAM40314.1 - 0.15 11.0 0.2 0.24 10.3 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YukC PF10140.9 GAM40314.1 - 0.2 10.5 0.1 0.29 9.9 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pex14_N PF04695.13 GAM40314.1 - 8.3 7.0 15.4 0.16 12.6 4.8 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3328 PF11807.8 GAM40315.1 - 2.5e-33 115.7 0.5 3.4e-33 115.3 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1746 PF08508.10 GAM40317.1 - 6.6e-41 139.3 1.8 9e-41 138.8 1.8 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Alg6_Alg8 PF03155.15 GAM40318.1 - 9e-127 424.0 24.7 1.1e-79 268.7 9.3 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family COX17 PF05051.13 GAM40319.1 - 3.4e-22 78.5 7.4 4e-22 78.3 7.4 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 GAM40319.1 - 0.017 15.1 3.3 0.27 11.3 0.0 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 GAM40319.1 - 6.7 7.0 8.8 2.4 8.5 5.4 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) LRR_6 PF13516.6 GAM40320.1 - 2.1e-12 46.0 6.8 0.016 15.2 0.0 8.1 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 GAM40320.1 - 0.00025 21.4 12.0 5.7 7.5 0.0 5.6 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM40320.1 - 0.0043 17.4 2.1 84 4.3 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich Repeat DUF4530 PF15039.6 GAM40320.1 - 0.052 13.7 3.9 0.068 13.3 2.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) TFIIS_M PF07500.14 GAM40321.1 - 5.4e-32 110.6 0.8 8.8e-32 109.9 0.2 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 GAM40321.1 - 1.1e-18 66.8 4.6 1.7e-18 66.2 4.6 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 GAM40321.1 - 1e-13 51.0 2.5 1.4e-13 50.7 0.7 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.8 GAM40321.1 - 0.068 12.9 0.1 0.068 12.9 0.1 1.9 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Pectinesterase PF01095.19 GAM40323.1 - 4.7e-25 87.9 2.5 6.1e-21 74.4 2.0 2.1 2 0 0 2 2 2 2 Pectinesterase Hydantoinase_B PF02538.14 GAM40324.1 - 1.6e-206 686.7 0.4 2.1e-206 686.3 0.4 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 GAM40324.1 - 1.4e-91 306.8 0.0 2.3e-91 306.0 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GAM40324.1 - 7.2e-51 172.4 0.1 2.8e-48 164.0 0.0 3.3 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Fungal_trans PF04082.18 GAM40325.1 - 3.1e-27 95.3 0.0 5.1e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40325.1 - 6.2e-07 29.4 7.2 1e-06 28.7 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATase PF00117.28 GAM40326.1 - 7.6e-06 25.8 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 GAM40326.1 - 0.046 13.3 0.0 0.071 12.7 0.0 1.4 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.16 GAM40327.1 - 2.5e-29 102.3 24.5 2.5e-29 102.3 24.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 GAM40327.1 - 3.9 7.1 7.6 8.3 6.0 0.3 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) FAA_hydrolase PF01557.18 GAM40328.1 - 4.9e-55 186.6 0.0 8.2e-55 185.8 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.18 GAM40328.1 - 1.9e-14 53.4 0.3 3e-14 52.7 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40329.1 - 1.8e-08 34.4 11.8 2.9e-08 33.7 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM40329.1 - 0.042 12.9 0.4 0.093 11.7 0.4 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain Scytalone_dh PF02982.14 GAM40330.1 - 2.4e-23 82.7 0.2 3.2e-23 82.3 0.2 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 GAM40330.1 - 7.2e-10 39.1 0.5 9.1e-10 38.7 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain Sugar_tr PF00083.24 GAM40331.1 - 6.1e-87 292.3 25.1 7e-87 292.2 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM40331.1 - 5e-28 98.1 21.3 5.1e-28 98.0 18.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MauE PF07291.11 GAM40331.1 - 0.11 12.2 2.9 0.17 11.6 1.3 2.0 2 0 0 2 2 2 0 Methylamine utilisation protein MauE MIP PF00230.20 GAM40332.1 - 4e-35 121.6 4.8 5.1e-35 121.2 4.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein p450 PF00067.22 GAM40333.1 - 4.9e-68 230.0 0.0 5.6e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 GAM40334.1 - 3.1e-12 46.1 0.0 8.2e-12 44.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40334.1 - 1.3e-06 28.4 14.8 2.2e-06 27.7 14.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_15 PF01793.16 GAM40335.1 - 4.1e-52 177.5 0.9 5.1e-52 177.1 0.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase E1-E2_ATPase PF00122.20 GAM40336.1 - 5.2e-40 136.9 8.7 6.1e-40 136.7 0.1 3.2 4 0 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 GAM40336.1 - 1.3e-16 61.5 0.0 5e-16 59.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM40336.1 - 3.4e-09 36.3 0.0 2.9e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM40336.1 - 0.0027 17.5 0.2 0.0068 16.2 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM40336.1 - 0.039 14.0 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) GNVR PF13807.6 GAM40336.1 - 0.19 11.7 1.5 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase HSP70 PF00012.20 GAM40337.1 - 2.1e-05 22.9 0.0 4.3e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein Cytochrom_C_2 PF01322.20 GAM40338.1 - 0.11 13.4 2.7 1.4 9.8 0.0 2.5 2 0 0 2 2 2 0 Cytochrome C' Jnk-SapK_ap_N PF09744.9 GAM40338.1 - 0.25 11.6 17.5 0.067 13.4 6.0 3.3 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Epimerase PF01370.21 GAM40339.1 - 5.5e-13 48.9 0.2 1.9e-12 47.2 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM40339.1 - 9.8e-11 41.9 0.0 1.4e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM40339.1 - 1e-08 35.1 0.1 1.5e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 GAM40339.1 - 4.3e-08 32.5 0.0 6.5e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM40339.1 - 1.8e-07 30.9 0.3 1.1e-06 28.3 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAM40339.1 - 3.6e-07 29.6 0.0 4.1e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 GAM40339.1 - 1.2e-05 24.9 0.1 1.7e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 GAM40339.1 - 3.3e-05 24.1 0.0 6.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 GAM40339.1 - 0.00025 21.3 0.0 0.00044 20.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 GAM40339.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 KR domain F420_oxidored PF03807.17 GAM40339.1 - 0.021 15.4 0.1 0.042 14.4 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 GAM40339.1 - 0.031 14.4 0.1 0.069 13.3 0.1 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 GAM40339.1 - 0.045 12.9 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Methyltransf_11 PF08241.12 GAM40339.1 - 0.048 14.3 0.0 0.092 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.6 GAM40339.1 - 0.054 13.0 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Sugar_tr PF00083.24 GAM40340.1 - 4e-88 296.3 27.1 4.9e-88 296.0 27.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM40340.1 - 9.4e-23 80.7 28.7 9.4e-23 80.7 28.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 GAM40340.1 - 0.028 14.6 1.7 0.067 13.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Amidoligase_2 PF12224.8 GAM40341.1 - 3.5e-17 62.9 0.0 7.2e-17 61.9 0.0 1.5 1 1 0 1 1 1 1 Putative amidoligase enzyme Sua5_yciO_yrdC PF01300.18 GAM40341.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Telomere recombination B277 PF17623.2 GAM40342.1 - 0.18 10.9 1.0 0.23 10.5 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function Glyco_hydro_cc PF11790.8 GAM40343.1 - 3.6e-60 203.5 3.2 4.3e-60 203.2 3.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fungal_trans_2 PF11951.8 GAM40344.1 - 1e-08 34.4 0.4 1.5e-08 33.9 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40344.1 - 5.5e-08 32.8 5.0 1.1e-07 31.9 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 GAM40345.1 - 1.4e-40 139.5 0.2 1.6e-40 139.2 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 GAM40346.1 - 1.1e-29 103.3 0.1 1.9e-29 102.5 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.16 GAM40347.1 - 1.4e-23 83.4 33.5 1.4e-23 83.4 33.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM40347.1 - 4.3e-08 32.0 8.6 7.5e-08 31.3 8.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM40347.1 - 1.5e-05 24.1 6.8 1.5e-05 24.1 6.8 2.4 1 1 0 2 2 2 1 Sugar (and other) transporter Lactamase_B PF00753.27 GAM40348.1 - 1.7e-07 31.4 0.1 1.1e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM40348.1 - 8.4e-06 25.4 0.4 1.9e-05 24.3 0.2 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 GAM40348.1 - 0.0048 16.4 0.0 0.0084 15.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain ABC1 PF03109.16 GAM40349.1 - 8.2e-22 77.6 0.3 2.9e-21 75.8 0.1 2.0 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 GAM40349.1 - 0.0011 18.9 0.1 0.17 11.8 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family MmgE_PrpD PF03972.14 GAM40350.1 - 6.2e-119 397.4 0.5 7.6e-119 397.1 0.5 1.1 1 0 0 1 1 1 1 MmgE/PrpD family Goodbye PF17109.5 GAM40351.1 - 1e-37 129.3 0.0 1.8e-36 125.2 0.0 3.0 3 0 0 3 3 3 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 GAM40351.1 - 3.7e-08 33.5 0.2 1.8e-07 31.2 0.0 2.3 3 0 0 3 3 2 1 NACHT domain AAA_16 PF13191.6 GAM40351.1 - 2.2e-07 31.4 0.1 3.2e-06 27.6 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAM40351.1 - 9.4e-06 25.9 0.0 4.4e-05 23.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAM40351.1 - 0.002 18.5 0.1 0.02 15.3 0.0 2.7 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAM40351.1 - 0.0034 17.8 0.0 0.0091 16.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase FYVE PF01363.21 GAM40351.1 - 0.032 14.4 2.5 0.076 13.2 2.5 1.6 1 0 0 1 1 1 0 FYVE zinc finger AAA_5 PF07728.14 GAM40351.1 - 0.034 14.1 0.0 0.47 10.4 0.0 2.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_12 PF13424.6 GAM40351.1 - 0.04 14.2 2.9 1.5 9.2 1.3 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM40351.1 - 0.068 13.3 0.5 49 4.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat NB-ARC PF00931.22 GAM40351.1 - 0.08 12.1 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 GAM40351.1 - 0.12 11.5 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 GAM40351.1 - 0.19 12.1 0.0 0.54 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain PAPS_reduct PF01507.19 GAM40353.1 - 5.5e-28 98.2 0.0 4.6e-19 69.1 0.0 2.3 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family T4_Gp59_N PF08993.10 GAM40353.1 - 0.032 14.6 0.1 7.8 7.0 0.0 2.2 2 0 0 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase SNARE PF05739.19 GAM40354.1 - 1.3e-13 50.7 0.6 2.2e-13 50.0 0.1 1.7 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 GAM40354.1 - 2.2e-10 39.4 0.4 4.8e-10 38.4 0.4 1.6 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 GAM40354.1 - 0.00083 19.6 4.0 0.22 11.8 0.1 3.2 4 0 0 4 4 4 2 Uncharacterized conserved protein Syntaxin PF00804.25 GAM40354.1 - 0.0021 17.7 5.8 0.009 15.7 0.1 2.7 2 0 0 2 2 2 1 Syntaxin Syntaxin-18_N PF10496.9 GAM40354.1 - 0.094 13.0 2.6 0.43 10.8 0.0 2.9 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus NPV_P10 PF05531.12 GAM40354.1 - 0.17 12.4 3.0 15 6.1 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4988 PF16378.5 GAM40354.1 - 0.35 10.5 4.5 7.2 6.2 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function LTXXQ PF07813.12 GAM40354.1 - 6.6 7.5 11.3 2.4 8.9 0.7 3.8 3 1 1 4 4 4 0 LTXXQ motif family protein ADH_zinc_N PF00107.26 GAM40355.1 - 2.2e-08 34.2 0.1 2.4e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM40355.1 - 0.00024 20.9 0.2 0.00047 20.0 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF3237 PF11578.8 GAM40356.1 - 5e-42 143.3 0.0 5.6e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF2235 PF09994.9 GAM40357.1 - 2.1e-77 260.3 0.0 2.6e-77 260.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) NACHT PF05729.12 GAM40359.1 - 4.1e-05 23.5 0.0 0.0019 18.1 0.0 2.6 1 1 0 1 1 1 1 NACHT domain Ank_4 PF13637.6 GAM40359.1 - 8.2e-05 23.1 0.0 0.72 10.5 0.0 4.2 5 0 0 5 5 4 1 Ankyrin repeats (many copies) AAA_16 PF13191.6 GAM40359.1 - 0.00043 20.7 0.1 0.0016 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAM40359.1 - 0.00083 19.6 0.1 0.0071 16.6 0.1 2.7 1 1 0 1 1 1 1 AAA domain Ank_5 PF13857.6 GAM40359.1 - 0.0041 17.4 0.0 1.6 9.1 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM40359.1 - 0.0072 16.9 0.0 0.02 15.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_18 PF13238.6 GAM40359.1 - 0.011 16.3 0.0 0.093 13.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAM40359.1 - 0.017 14.3 0.0 0.042 13.0 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 GAM40359.1 - 0.088 12.6 0.0 0.32 10.8 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 GAM40359.1 - 0.093 13.1 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 GAM40359.1 - 0.12 12.9 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 GAM40359.1 - 0.12 12.5 0.0 0.43 10.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.18 GAM40360.1 - 1.1e-07 31.9 11.6 1.1e-07 31.9 11.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 GAM40361.1 - 2.7e-86 290.2 14.1 3.2e-86 290.0 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM40361.1 - 1.3e-41 142.7 39.9 1.4e-31 109.8 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MerR-DNA-bind PF09278.11 GAM40361.1 - 0.11 13.1 0.1 2.7 8.6 0.1 2.4 2 0 0 2 2 2 0 MerR, DNA binding DUF2182 PF09948.9 GAM40361.1 - 0.11 12.3 3.6 0.6 10.0 0.1 2.6 2 0 0 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) MFS_1_like PF12832.7 GAM40361.1 - 0.66 8.8 16.7 0.89 8.3 2.5 3.1 2 1 0 2 2 2 0 MFS_1 like family MFS_1 PF07690.16 GAM40362.1 - 1e-35 123.4 49.0 4.8e-29 101.4 22.4 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM40362.1 - 0.00043 19.3 1.5 0.00043 19.3 1.5 3.8 3 2 1 4 4 4 2 Sugar (and other) transporter DUF2583 PF10762.9 GAM40362.1 - 0.37 11.2 4.0 0.35 11.3 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) Glyco_hydro_3_C PF01915.22 GAM40363.1 - 6.7e-55 186.2 0.0 2.3e-54 184.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAM40363.1 - 3.8e-49 167.8 0.0 6e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM40363.1 - 1.1e-22 79.9 0.0 2.5e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 GAM40363.1 - 7.8e-12 45.2 0.0 1.3e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 PA14 domain PA_decarbox PF05870.11 GAM40364.1 - 1.1e-08 34.9 0.1 1.4e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) DEC-1_N PF04625.13 GAM40365.1 - 4.6 6.2 10.9 7.4 5.5 10.9 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ion_trans_2 PF07885.16 GAM40366.1 - 1.5e-24 85.7 28.3 1.9e-15 56.5 9.4 3.4 4 0 0 4 4 4 2 Ion channel Lig_chan PF00060.26 GAM40366.1 - 6.2 6.7 12.6 0.4 10.5 6.3 2.2 2 1 0 2 2 2 0 Ligand-gated ion channel SUR7 PF06687.12 GAM40367.1 - 2e-28 99.5 11.1 2.9e-28 99.0 11.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Pox_P21 PF05313.12 GAM40367.1 - 0.02 14.5 1.7 0.035 13.7 1.7 1.3 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DUF2298 PF10060.9 GAM40367.1 - 0.078 11.7 3.5 0.13 10.9 3.5 1.2 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) DUF3043 PF11241.8 GAM40367.1 - 0.55 10.2 1.5 1.3 9.1 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF4381 PF14316.6 GAM40367.1 - 0.94 9.7 4.7 0.26 11.5 1.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) adh_short_C2 PF13561.6 GAM40368.1 - 3.4e-63 213.3 0.0 3.9e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM40368.1 - 3.4e-43 147.4 0.0 4e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM40368.1 - 6e-15 55.6 0.0 8e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 GAM40369.1 - 2.3e-36 125.1 0.0 3.2e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40369.1 - 2.4e-27 96.0 0.0 3.4e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40369.1 - 4.6e-09 36.5 0.1 7.3e-08 32.5 0.1 2.1 1 1 0 1 1 1 1 KR domain UPF0146 PF03686.13 GAM40369.1 - 3.3e-05 23.8 0.1 8e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0146) Epimerase PF01370.21 GAM40369.1 - 9.7e-05 21.9 0.0 0.00021 20.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 GAM40369.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 GAM40369.1 - 0.13 12.2 0.0 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding EBP PF05241.12 GAM40370.1 - 6.4e-59 198.4 9.0 7.5e-59 198.2 9.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein Abhydrolase_6 PF12697.7 GAM40371.1 - 8.4e-06 26.5 0.0 2.7e-05 24.9 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM40371.1 - 0.0042 16.4 0.1 0.039 13.2 0.1 2.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 MnmE_helical PF12631.7 GAM40371.1 - 0.17 12.0 0.0 0.41 10.8 0.0 1.6 1 1 0 1 1 1 0 MnmE helical domain DAO PF01266.24 GAM40373.1 - 8.9e-25 88.0 0.0 1.2e-24 87.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM40373.1 - 0.014 15.4 0.0 0.07 13.1 0.0 2.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAM40374.1 - 3e-19 69.4 0.0 6.5e-16 58.4 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM40374.1 - 1.3e-17 64.0 0.0 2.7e-14 53.1 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAM40374.1 - 3.4e-14 52.2 0.0 3.8e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAM40374.1 - 2.6e-10 40.0 0.0 1.1e-06 28.1 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 GAM40374.1 - 1.7e-07 31.7 0.2 0.015 15.9 0.1 3.1 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAM40374.1 - 1.8e-06 27.4 0.0 5.6e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GAM40374.1 - 1.1e-05 25.6 0.0 9.6e-05 22.5 0.0 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAM40374.1 - 0.00073 18.7 1.6 0.039 13.0 0.0 2.9 4 0 0 4 4 4 1 Glucose inhibited division protein A DAO PF01266.24 GAM40374.1 - 0.0012 18.5 0.8 0.14 11.8 0.2 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 GAM40374.1 - 0.0012 18.7 0.1 0.8 9.6 0.0 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAM40374.1 - 0.0027 17.1 0.0 0.036 13.4 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 GAM40374.1 - 0.0028 16.4 0.1 0.017 13.9 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 GAM40374.1 - 0.0048 16.0 0.4 0.018 14.1 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 GAM40374.1 - 0.0058 16.7 0.0 0.87 9.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 GAM40374.1 - 0.0079 15.3 0.0 0.26 10.3 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein TrkA_N PF02254.18 GAM40374.1 - 0.01 16.1 0.1 0.92 9.8 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.17 GAM40374.1 - 0.023 13.9 0.0 0.08 12.2 0.0 1.9 2 0 0 2 2 2 0 Thi4 family SnoaL_2 PF12680.7 GAM40374.1 - 0.027 15.1 0.0 0.088 13.5 0.0 1.9 1 0 0 1 1 1 0 SnoaL-like domain ApbA PF02558.16 GAM40374.1 - 0.031 13.9 0.0 1.1 8.9 0.0 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 GAM40374.1 - 0.037 14.0 0.4 17 5.4 0.1 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding IlvN PF07991.12 GAM40374.1 - 0.042 13.4 0.2 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_oxidored PF12831.7 GAM40374.1 - 0.055 12.8 0.1 0.086 12.2 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase adh_short PF00106.25 GAM40374.1 - 0.056 12.9 0.1 7.1 6.0 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase DUF1479 PF07350.12 GAM40375.1 - 1.4e-158 528.1 0.0 1.7e-158 527.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) 5_nucleotid_C PF02872.18 GAM40376.1 - 5.4e-05 23.5 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Chromate_transp PF02417.15 GAM40377.1 - 1.2e-61 207.5 35.9 6.9e-31 107.5 12.9 2.7 2 1 0 2 2 2 2 Chromate transporter bZIP_1 PF00170.21 GAM40378.1 - 2.2 8.5 11.9 5.6 7.2 11.8 1.7 1 1 1 2 2 2 0 bZIP transcription factor Drc1-Sld2 PF11719.8 GAM40381.1 - 2e-109 367.2 45.2 1.3e-107 361.2 45.2 2.0 1 1 0 1 1 1 1 DNA replication and checkpoint protein Fungal_trans PF04082.18 GAM40383.1 - 9.9e-14 51.0 0.2 1.9e-13 50.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40383.1 - 1.1e-09 38.3 7.8 1.8e-09 37.6 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suc_Fer-like PF06999.12 GAM40384.1 - 2.8e-69 232.9 0.0 3.3e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Flavodoxin_NdrI PF07972.11 GAM40384.1 - 0.09 13.0 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 NrdI Flavodoxin like MARVEL PF01284.23 GAM40385.1 - 8.7e-26 90.7 8.6 1e-25 90.4 8.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4064 PF13273.6 GAM40385.1 - 0.004 17.4 2.6 0.59 10.4 0.1 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) Frag1 PF10277.9 GAM40385.1 - 0.17 11.4 6.2 0.3 10.6 6.2 1.4 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family CTV_P33 PF07184.11 GAM40386.1 - 0.066 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein NAGLU PF05089.12 GAM40387.1 - 8.6e-135 449.0 5.8 8.6e-135 449.0 5.8 2.0 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 GAM40387.1 - 3.5e-73 246.4 5.2 6e-73 245.6 5.2 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 GAM40387.1 - 5.5e-22 77.3 0.0 1.5e-21 76.0 0.0 1.8 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain His_Phos_1 PF00300.22 GAM40387.1 - 3.1e-13 49.9 0.2 1.4e-12 47.8 0.2 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_L22 PF00237.19 GAM40389.1 - 2.1e-29 101.8 0.0 3.7e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1640 PF07798.11 GAM40390.1 - 1.8e-54 184.4 11.1 2.4e-54 184.0 11.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DnaJ PF00226.31 GAM40391.1 - 4.9e-11 42.6 0.2 3.1e-10 40.0 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain MFS_1 PF07690.16 GAM40392.1 - 1.2e-40 139.6 48.7 2.7e-40 138.4 48.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 GAM40392.1 - 4.9e-36 124.3 1.1 7.4e-36 123.8 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2-Hacid_dh_C PF02826.19 GAM40392.1 - 1.5e-35 122.2 0.0 2.5e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sugar_tr PF00083.24 GAM40392.1 - 5.6e-12 45.3 2.8 5.6e-12 45.3 2.8 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter 2-Hacid_dh PF00389.30 GAM40392.1 - 1e-07 31.7 0.0 2.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Hydantoinase_B PF02538.14 GAM40393.1 - 4.6e-209 695.1 0.0 6.1e-209 694.7 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 GAM40393.1 - 8.7e-94 314.0 0.1 1.8e-93 313.0 0.1 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GAM40393.1 - 7.9e-58 195.1 0.1 4e-56 189.5 0.0 2.8 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region Peptidase_M19 PF01244.21 GAM40394.1 - 6.4e-104 347.6 0.4 7.4e-104 347.3 0.4 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) GDPD_2 PF13653.6 GAM40394.1 - 0.04 14.4 0.3 0.17 12.4 0.1 2.2 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family MFS_1 PF07690.16 GAM40395.1 - 1.2e-37 129.7 29.4 1.2e-37 129.7 29.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM40395.1 - 3.8e-27 95.0 0.2 7e-27 94.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain UNC-93 PF05978.16 GAM40395.1 - 6.1 6.5 9.3 0.17 11.6 1.7 2.3 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Peptidase_M20 PF01546.28 GAM40396.1 - 1.9e-22 80.0 0.0 7.3e-22 78.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM40396.1 - 1.9e-16 60.0 0.0 3.1e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAM40396.1 - 0.00061 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 ACP_syn_III_C PF08541.10 GAM40396.1 - 0.081 13.1 0.5 6.6 7.0 0.0 2.5 1 1 1 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Aminotran_1_2 PF00155.21 GAM40397.1 - 6.2e-71 239.5 0.0 7.1e-71 239.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAM40397.1 - 0.016 14.5 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase zf-C2H2 PF00096.26 GAM40398.1 - 3.5e-05 24.0 14.3 0.028 14.9 4.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM40398.1 - 0.0001 22.8 12.0 0.014 16.2 3.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 GAM40398.1 - 0.098 13.1 0.2 5.6 7.5 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CDO_I PF05995.12 GAM40398.1 - 0.1 11.9 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Cysteine dioxygenase type I zf-H2C2_2 PF13465.6 GAM40398.1 - 2.6 8.6 16.7 0.13 12.7 6.2 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Sugar_tr PF00083.24 GAM40399.1 - 2.7e-37 128.7 27.6 1.5e-35 123.0 27.6 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM40399.1 - 2.1e-35 122.3 49.1 3.3e-32 111.8 31.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4126 PF13548.6 GAM40399.1 - 0.0025 17.5 1.5 0.0025 17.5 1.5 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4126) CN_hydrolase PF00795.22 GAM40400.1 - 7.1e-43 146.8 0.0 1e-42 146.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Amidohydro_1 PF01979.20 GAM40401.1 - 6.3e-24 84.9 0.0 1.1e-23 84.1 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM40401.1 - 4.9e-17 62.6 0.0 1.7e-07 31.1 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family DAO PF01266.24 GAM40402.1 - 2.7e-32 112.7 0.1 5.2e-32 111.8 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM40402.1 - 0.019 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 GAM40402.1 - 0.07 13.4 0.5 0.19 12.0 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM40402.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM40402.1 - 0.11 11.7 0.1 0.47 9.6 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Asp_Glu_race PF01177.22 GAM40403.1 - 4.2e-08 33.3 0.1 5.5e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase TPR_MLP1_2 PF07926.12 GAM40404.1 - 0.00034 20.7 23.5 0.00034 20.7 23.5 2.4 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 GAM40404.1 - 0.023 13.4 22.7 0.04 12.6 22.7 1.3 1 0 0 1 1 1 0 AAA domain XhlA PF10779.9 GAM40404.1 - 0.025 14.8 7.6 0.025 14.8 7.6 3.8 2 1 1 3 3 3 0 Haemolysin XhlA LMBR1 PF04791.16 GAM40404.1 - 0.077 11.9 7.8 0.086 11.7 7.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF812 PF05667.11 GAM40404.1 - 0.088 11.7 25.7 0.15 10.9 25.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) MobL PF18555.1 GAM40404.1 - 0.12 11.6 19.4 0.19 11.0 19.4 1.2 1 0 0 1 1 1 0 MobL relaxases MMPL PF03176.15 GAM40404.1 - 0.19 10.6 2.3 1.3 7.9 2.6 1.9 2 0 0 2 2 2 0 MMPL family Exonuc_VII_L PF02601.15 GAM40404.1 - 0.19 11.3 16.1 0.041 13.5 12.7 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Laminin_II PF06009.12 GAM40404.1 - 0.2 11.7 16.4 0.082 12.9 12.6 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF4407 PF14362.6 GAM40404.1 - 0.44 9.9 22.6 1.1 8.6 22.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 GAM40404.1 - 0.78 8.6 38.4 0.049 12.5 21.3 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein KASH_CCD PF14662.6 GAM40404.1 - 1.4 8.7 31.6 3.2 7.5 31.4 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF5082 PF16888.5 GAM40404.1 - 2.3 8.5 25.0 0.11 12.8 16.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) ATG16 PF08614.11 GAM40404.1 - 2.4 8.3 28.7 3.9 7.7 25.9 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4164 PF13747.6 GAM40404.1 - 2.4 8.5 22.3 0.13 12.6 4.2 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.11 GAM40404.1 - 3.4 8.1 15.6 3 8.3 1.5 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 GAM40404.1 - 6.4 6.9 38.2 0.3 11.1 11.2 3.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding FAD_binding_3 PF01494.19 GAM40405.1 - 2e-66 224.7 0.0 5e-66 223.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAM40405.1 - 7e-40 136.8 0.0 1.2e-39 136.0 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 GAM40405.1 - 2.5e-05 23.2 0.1 4.5e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAM40405.1 - 9.7e-05 21.7 0.1 0.00024 20.5 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM40405.1 - 0.00015 21.1 0.0 0.00028 20.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 GAM40405.1 - 0.00046 19.4 0.2 0.00088 18.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAM40405.1 - 0.00057 19.3 0.4 0.00089 18.7 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 GAM40405.1 - 0.0014 17.8 0.2 0.0021 17.2 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 GAM40405.1 - 0.0053 16.4 0.0 0.034 13.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAM40405.1 - 0.006 15.9 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 GAM40405.1 - 0.0093 16.2 0.1 0.027 14.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAM40405.1 - 0.011 16.3 0.1 0.021 15.3 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM40405.1 - 0.024 13.9 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 GAM40405.1 - 0.11 13.0 0.0 0.44 11.1 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 GAM40405.1 - 0.12 11.4 0.1 0.22 10.6 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 GAM40405.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase ADH_zinc_N PF00107.26 GAM40406.1 - 2.4e-09 37.2 0.0 5.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAM40406.1 - 0.096 12.0 1.0 0.17 11.2 1.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF834 PF05754.14 GAM40406.1 - 0.26 11.3 4.3 4.7 7.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF834) GST_N PF02798.20 GAM40407.1 - 2.6e-12 46.9 0.0 4.6e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM40407.1 - 4.2e-12 46.1 0.0 7.8e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM40407.1 - 1.8e-09 37.9 0.0 3.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM40407.1 - 3.1e-08 33.7 0.1 4.4e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM40407.1 - 7.1e-07 29.4 0.0 1.3e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM40407.1 - 0.0074 16.3 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.10 GAM40407.1 - 0.18 12.3 0.0 0.28 11.7 0.0 1.5 1 1 0 1 1 1 0 MetRS-N binding domain ABC2_membrane PF01061.24 GAM40408.1 - 1.5e-87 292.4 61.9 2.8e-45 154.3 25.6 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 GAM40408.1 - 1.9e-35 120.6 9.4 5.5e-33 112.7 0.1 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 GAM40408.1 - 2.9e-33 115.3 0.0 2.7e-16 60.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 GAM40408.1 - 1e-15 58.1 0.0 2.3e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal Ank_2 PF12796.7 GAM40408.1 - 2.8e-09 37.4 0.0 0.0057 17.2 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) AAA_16 PF13191.6 GAM40408.1 - 6e-09 36.5 0.3 0.00042 20.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain Ank_3 PF13606.6 GAM40408.1 - 3.4e-07 30.0 0.0 0.77 10.5 0.0 5.3 5 0 0 5 5 4 1 Ankyrin repeat AAA_25 PF13481.6 GAM40408.1 - 2.5e-06 27.2 0.3 0.00018 21.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 GAM40408.1 - 5.3e-06 26.6 0.0 0.1 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAM40408.1 - 7.3e-06 26.0 0.0 0.0019 18.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Ank_4 PF13637.6 GAM40408.1 - 3.8e-05 24.2 0.1 0.043 14.4 0.1 3.8 2 2 1 4 4 4 1 Ankyrin repeats (many copies) AAA_21 PF13304.6 GAM40408.1 - 0.0001 22.2 0.1 1.1 9.0 0.0 3.2 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Ank_5 PF13857.6 GAM40408.1 - 0.00016 21.9 0.0 5.2 7.5 0.0 4.5 5 0 0 5 5 4 2 Ankyrin repeats (many copies) AAA_18 PF13238.6 GAM40408.1 - 0.00021 21.9 0.0 0.12 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAM40408.1 - 0.0003 20.5 0.8 0.034 13.9 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 GAM40408.1 - 0.00056 20.2 0.3 0.23 11.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain Ank PF00023.30 GAM40408.1 - 0.0019 18.6 0.1 0.23 11.9 0.0 3.9 4 0 0 4 4 3 1 Ankyrin repeat SMC_N PF02463.19 GAM40408.1 - 0.0045 16.5 0.0 1.9 7.8 0.0 3.4 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 GAM40408.1 - 0.0065 16.4 0.3 0.53 10.2 0.1 2.6 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 GAM40408.1 - 0.0091 15.6 0.3 0.27 10.8 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 GAM40408.1 - 0.035 14.6 0.0 0.076 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 GAM40408.1 - 0.045 14.2 0.2 6.2 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAM40408.1 - 0.058 13.1 0.1 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain HalX PF08663.10 GAM40408.1 - 0.079 13.3 0.1 23 5.4 0.0 2.6 2 0 0 2 2 2 0 HalX domain AAA_24 PF13479.6 GAM40408.1 - 0.092 12.5 0.6 15 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAM40408.1 - 0.11 12.7 0.2 5.9 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GAM40408.1 - 0.2 12.0 0.2 36 4.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane_3 PF12698.7 GAM40408.1 - 8.4 5.4 42.7 1.8 7.6 17.1 2.8 2 1 0 2 2 2 0 ABC-2 family transporter protein PRA1 PF03208.19 GAM40409.1 - 1.1e-37 128.9 0.3 1.3e-37 128.6 0.3 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF2207 PF09972.9 GAM40409.1 - 0.14 10.8 0.7 0.17 10.6 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) VirB3 PF05101.13 GAM40409.1 - 2.9 8.2 6.8 1.3 9.4 0.2 2.1 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein YL1 PF05764.13 GAM40410.1 - 0.024 14.7 20.9 0.034 14.2 4.6 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 GAM40410.1 - 0.11 12.3 21.8 0.4 10.4 13.3 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 GAM40410.1 - 0.31 10.6 10.7 1.8 8.1 0.3 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting PBP1_TM PF14812.6 GAM40410.1 - 0.32 11.4 23.2 0.11 12.8 8.2 4.3 3 1 1 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 GAM40410.1 - 0.37 8.8 11.8 0.63 8.1 11.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 GAM40410.1 - 1.5 9.1 10.2 3.9 7.7 10.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FYDLN_acid PF09538.10 GAM40410.1 - 6.2 7.6 16.4 1.2 9.9 11.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Frag1 PF10277.9 GAM40411.1 - 6.9e-48 163.1 13.6 8e-48 162.9 13.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family CBP_BcsF PF11120.8 GAM40411.1 - 0.11 12.6 0.5 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF DUF2070 PF09843.9 GAM40411.1 - 1.7 6.9 13.9 0.29 9.4 9.5 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Y_phosphatase3 PF13350.6 GAM40412.1 - 2.3e-41 142.3 0.0 3e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 GAM40412.1 - 5.9e-08 32.5 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAM40412.1 - 0.0029 17.2 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 GAM40412.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 GAM40412.1 - 0.059 12.3 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Init_tRNA_PT PF04179.12 GAM40412.1 - 0.15 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Glyco_hydro_35 PF01301.19 GAM40413.1 - 2.8e-81 273.6 2.8 4.4e-81 272.9 2.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 GAM40413.1 - 2.6e-51 174.0 7.4 5.4e-51 173.0 7.4 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 GAM40413.1 - 3.2e-51 172.7 6.8 6e-25 88.0 0.0 3.4 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 GAM40413.1 - 1.5e-23 82.1 0.1 6.4e-23 80.1 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 GAM40413.1 - 9.9e-05 21.8 0.0 0.002 17.5 0.0 2.2 1 1 1 2 2 2 1 Beta-galactosidase Cellulase PF00150.18 GAM40413.1 - 0.00029 20.4 0.2 0.0011 18.4 0.2 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydr_30_2 PF14587.6 GAM40414.1 - 3.2e-18 66.5 6.4 6.3e-16 58.9 0.2 2.8 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 GAM40414.1 - 1.2e-14 54.2 4.5 5e-14 52.3 4.5 2.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain CBM_1 PF00734.18 GAM40414.1 - 5.4e-13 48.6 15.2 5.4e-13 48.6 15.2 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_30 PF02055.16 GAM40414.1 - 8.6e-09 34.8 2.5 1.1e-08 34.5 0.7 1.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 GAM40414.1 - 2.3e-08 33.6 1.5 4.3e-08 32.7 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_62 PF03664.13 GAM40415.1 - 8.3e-130 432.0 9.2 1.1e-129 431.6 9.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.18 GAM40415.1 - 1.4e-11 44.1 17.7 4.4e-11 42.6 17.7 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Tannase PF07519.11 GAM40416.1 - 1.2e-141 472.9 5.4 1.4e-141 472.6 5.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase FMO-like PF00743.19 GAM40417.1 - 3e-31 108.4 0.1 8.4e-13 47.6 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAM40417.1 - 4.6e-13 49.1 0.6 6.1e-10 38.8 0.3 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM40417.1 - 1.2e-07 31.3 0.1 0.0045 16.3 0.0 3.0 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM40417.1 - 9.1e-07 28.3 0.3 0.00033 19.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAM40417.1 - 0.00025 21.1 0.1 0.0092 16.0 0.0 2.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAM40417.1 - 0.00028 21.1 0.0 0.00072 19.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM40417.1 - 0.025 14.1 0.7 0.42 10.2 0.7 2.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 GAM40417.1 - 0.035 14.2 0.0 2.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 GAM40417.1 - 0.086 12.3 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Thi4 PF01946.17 GAM40417.1 - 0.11 11.7 0.2 0.46 9.7 0.1 2.0 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 GAM40417.1 - 0.14 10.9 0.1 0.27 9.9 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Peptidase_M20 PF01546.28 GAM40418.1 - 8.3e-19 68.1 0.4 1.6e-18 67.2 0.4 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM40418.1 - 1.6e-14 53.7 0.2 3.8e-14 52.5 0.2 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.16 GAM40419.1 - 1.6e-45 155.6 58.5 3.1e-44 151.4 55.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM40419.1 - 3.6e-16 58.7 24.8 5e-16 58.3 24.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM40419.1 - 4.5e-13 48.9 11.5 4.5e-13 48.9 11.5 3.3 1 1 2 3 3 3 1 Sugar (and other) transporter DUF2140 PF09911.9 GAM40419.1 - 0.06 12.9 1.0 0.13 11.8 0.5 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) OATP PF03137.20 GAM40419.1 - 0.8 7.9 13.8 0.43 8.8 1.6 3.1 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 GAM40420.1 - 2.8e-19 69.2 0.2 9.3e-19 67.5 0.1 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.25 GAM40420.1 - 2e-05 24.8 0.0 6.2e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM40420.1 - 6.5e-05 23.3 0.0 0.00014 22.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM40420.1 - 0.00055 20.0 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 GAM40420.1 - 0.0036 17.3 0.0 0.0077 16.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM40420.1 - 0.075 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein 2-Hacid_dh_C PF02826.19 GAM40421.1 - 2.1e-42 144.5 0.0 1.5e-25 89.6 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 GAM40421.1 - 0.0003 21.3 0.0 0.00052 20.5 0.0 1.4 1 0 0 1 1 1 1 XdhC Rossmann domain 2-Hacid_dh PF00389.30 GAM40421.1 - 0.00076 19.1 0.0 0.001 18.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3HCDH_N PF02737.18 GAM40421.1 - 0.0022 17.9 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GAM40421.1 - 0.049 14.2 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 GAM40421.1 - 0.05 13.2 0.1 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Oxidored_nitro PF00148.19 GAM40421.1 - 0.084 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase NAD_binding_2 PF03446.15 GAM40421.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.24 GAM40421.1 - 0.12 12.8 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain TrkA_N PF02254.18 GAM40421.1 - 0.14 12.4 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain PrpR_N PF06506.11 GAM40421.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Propionate catabolism activator AdoHcyase_NAD PF00670.21 GAM40421.1 - 0.21 11.7 0.5 1 9.4 0.1 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MFS_1 PF07690.16 GAM40422.1 - 6.9e-13 48.2 30.9 6.9e-13 48.2 30.9 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily E1-E2_ATPase PF00122.20 GAM40424.1 - 3.8e-44 150.4 4.9 3.8e-44 150.4 4.9 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAM40424.1 - 3.7e-28 99.3 0.0 5.9e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FA_hydroxylase PF04116.13 GAM40424.1 - 1.4e-07 31.9 3.0 1.4e-07 31.9 3.0 3.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily HMA PF00403.26 GAM40424.1 - 6.7e-07 29.7 0.1 2.4e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Heavy-metal-associated domain Fungal_trans PF04082.18 GAM40425.1 - 6.1e-12 45.1 0.2 8.8e-12 44.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Eisosome1 PF12757.7 GAM40426.1 - 3.4e-37 127.5 18.4 3.4e-37 127.5 18.4 3.5 3 1 1 4 4 4 1 Eisosome protein 1 MFS_1 PF07690.16 GAM40426.1 - 4.1e-24 85.2 19.5 4.1e-24 85.2 19.5 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM40426.1 - 0.00056 18.9 8.6 0.00056 18.9 8.6 3.6 3 2 0 3 3 3 1 Sugar (and other) transporter CFEM PF05730.11 GAM40427.1 - 8.4e-12 45.0 16.0 8.4e-12 45.0 16.0 2.1 2 1 0 2 2 2 1 CFEM domain Macoilin PF09726.9 GAM40427.1 - 9.7 4.6 5.7 11 4.5 5.7 1.1 1 0 0 1 1 1 0 Macoilin family Ilm1 PF10311.9 GAM40428.1 - 1.3e-51 174.6 1.8 1.5e-51 174.3 1.8 1.1 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Choline_transpo PF04515.12 GAM40428.1 - 0.0045 16.2 0.4 0.0045 16.2 0.4 1.4 2 0 0 2 2 2 1 Plasma-membrane choline transporter Prenyltrans PF00432.21 GAM40429.1 - 1.8e-28 97.9 12.1 1.2e-07 31.3 0.3 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 GAM40429.1 - 0.00039 19.6 0.0 0.2 10.7 0.0 3.5 2 2 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 GAM40429.1 - 0.22 10.6 0.0 19 4.3 0.0 2.2 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain Pkinase PF00069.25 GAM40430.1 - 7.4e-67 225.5 0.0 1.2e-66 224.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM40430.1 - 9.5e-42 143.1 0.0 1.5e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM40430.1 - 3.2e-09 36.5 0.0 1.9e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAM40430.1 - 2.2e-06 26.9 0.1 2.2e-06 26.9 0.1 2.7 3 0 0 3 3 3 1 Haspin like kinase domain APH PF01636.23 GAM40430.1 - 0.018 15.0 0.3 0.83 9.5 0.3 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAM40430.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ferlin_C PF16165.5 GAM40430.1 - 0.17 11.9 0.6 0.37 10.7 0.6 1.5 1 0 0 1 1 1 0 Ferlin C-terminus E1-E2_ATPase PF00122.20 GAM40431.1 - 3.4e-52 176.6 6.2 2.6e-51 173.7 2.8 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAM40431.1 - 6.7e-44 149.8 4.7 6.7e-44 149.8 4.7 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAM40431.1 - 9.1e-23 81.6 1.8 4.4e-22 79.4 0.4 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM40431.1 - 4.8e-18 64.6 0.1 1.3e-17 63.2 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAM40431.1 - 6e-17 61.5 0.0 1.2e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAM40431.1 - 1.7e-08 34.5 0.9 3.6e-06 26.9 0.8 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAM40431.1 - 1.4e-06 28.9 0.0 5.6e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GHL6 PF14871.6 GAM40431.1 - 0.055 13.6 0.1 1.1 9.4 0.0 2.6 3 0 0 3 3 3 0 Hypothetical glycosyl hydrolase 6 Fumarate_red_D PF02313.17 GAM40431.1 - 0.061 13.4 0.8 0.72 10.0 0.1 2.6 2 0 0 2 2 2 0 Fumarate reductase subunit D 14-3-3 PF00244.20 GAM40432.1 - 2.9e-103 344.1 2.3 3.7e-103 343.8 2.3 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF1653 PF07866.11 GAM40432.1 - 0.055 13.8 0.3 7.6 6.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1653) eIF3_subunit PF08597.10 GAM40433.1 - 1.6e-73 247.6 35.0 1.8e-73 247.4 35.0 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PRP4 PF08799.11 GAM40433.1 - 0.37 10.4 1.9 0.67 9.6 1.9 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like PRCC PF10253.9 GAM40433.1 - 1.3 9.7 18.1 2.3 9.0 10.8 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting PBP_sp32 PF07222.12 GAM40433.1 - 2.4 7.6 8.0 4.7 6.6 8.0 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CCSAP PF15748.5 GAM40433.1 - 2.6 8.1 20.1 0.32 11.2 13.3 2.0 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated YL1 PF05764.13 GAM40433.1 - 3.6 7.6 30.5 9.6 6.2 10.8 2.2 1 1 1 2 2 2 0 YL1 nuclear protein CTP_synth_N PF06418.14 GAM40434.1 - 3.8e-122 406.7 0.4 4.3e-122 406.5 0.4 1.0 1 0 0 1 1 1 1 CTP synthase N-terminus Nucleic_acid_bd PF13820.6 GAM40434.1 - 0.073 12.9 0.0 3.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Putative nucleic acid-binding region ArsA_ATPase PF02374.15 GAM40434.1 - 0.17 11.1 0.2 0.34 10.1 0.0 1.6 2 0 0 2 2 2 0 Anion-transporting ATPase GATase PF00117.28 GAM40435.1 - 8.8e-51 172.4 0.0 1e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAM40435.1 - 6.3e-08 32.6 0.1 1.5e-07 31.4 0.1 1.6 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 GAM40435.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GSH-S_ATP PF02955.16 GAM40435.1 - 0.13 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Enolase_C PF00113.22 GAM40436.1 - 7.3e-153 508.0 0.0 9.6e-153 507.6 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GAM40436.1 - 1.1e-57 193.8 0.2 2e-57 193.0 0.2 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GAM40436.1 - 4.9e-05 23.0 0.0 9.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GAM40436.1 - 0.0054 15.9 0.3 3.5 6.7 0.0 3.0 3 0 0 3 3 3 2 Methylaspartate ammonia-lyase C-terminus Glyco_hydro_47 PF01532.20 GAM40437.1 - 1.4e-167 558.2 0.1 1.9e-167 557.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AAA PF00004.29 GAM40437.1 - 3e-42 144.2 0.0 6.9e-42 143.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAM40437.1 - 2.3e-11 43.5 0.2 2.5e-10 40.1 0.0 2.6 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAM40437.1 - 1.4e-10 40.8 0.1 2.7e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAM40437.1 - 2.5e-06 28.0 0.0 0.00027 21.4 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 GAM40437.1 - 1.9e-05 24.8 0.0 4.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAM40437.1 - 2.5e-05 24.3 0.0 0.0002 21.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAM40437.1 - 3e-05 23.8 0.0 6.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 GAM40437.1 - 0.0014 17.8 0.0 0.0034 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 GAM40437.1 - 0.0022 18.3 0.1 0.014 15.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAM40437.1 - 0.0025 18.4 0.0 0.013 16.1 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 GAM40437.1 - 0.0041 16.7 0.0 0.0084 15.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 GAM40437.1 - 0.0074 15.5 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 GAM40437.1 - 0.011 15.8 0.0 0.036 14.1 0.0 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 GAM40437.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAM40437.1 - 0.02 15.1 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAM40437.1 - 0.021 15.2 0.0 0.045 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 GAM40437.1 - 0.022 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Prot_ATP_OB_N PF17758.1 GAM40437.1 - 0.027 14.1 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_14 PF13173.6 GAM40437.1 - 0.031 14.3 0.0 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 GAM40437.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAM40437.1 - 0.052 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 GAM40437.1 - 0.062 13.0 0.2 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain GAS PF13851.6 GAM40437.1 - 0.087 12.2 3.1 0.063 12.6 1.3 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATPase PF06745.13 GAM40437.1 - 0.11 11.8 1.0 0.51 9.7 0.0 2.2 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 GAM40437.1 - 0.14 12.0 0.0 0.51 10.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 GAM40437.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 GAM40437.1 - 3.4 6.8 4.8 3.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT_sigma PF17106.5 GAM40438.1 - 2e-05 24.6 43.5 0.0024 18.0 9.9 5.9 4 2 2 6 6 6 4 Sigma domain on NACHT-NTPases TMEM61 PF15105.6 GAM40438.1 - 0.023 14.5 0.3 0.048 13.5 0.0 1.6 2 0 0 2 2 2 0 TMEM61 protein family DUF4607 PF15380.6 GAM40438.1 - 2.7 7.4 8.8 0.032 13.7 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4607) p450 PF00067.22 GAM40440.1 - 1.5e-58 198.7 0.1 1.9e-58 198.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cutinase PF01083.22 GAM40441.1 - 1.6e-39 135.7 0.3 1.9e-39 135.4 0.3 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 GAM40441.1 - 0.0012 18.4 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.7 GAM40441.1 - 0.024 15.3 0.9 0.027 15.1 0.9 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 GAM40441.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 GAM40441.1 - 0.17 11.6 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Amidase PF01425.21 GAM40442.1 - 0.034 13.1 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 Amidase M20_dimer PF07687.14 GAM40443.1 - 1.4e-18 66.8 0.1 2.8e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 GAM40443.1 - 1.4e-14 54.3 0.0 9.1e-14 51.6 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 GAM40443.1 - 0.0049 16.6 0.0 0.023 14.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M28 HATPase_c PF02518.26 GAM40444.1 - 2.1e-21 76.5 0.0 4.9e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM40444.1 - 2.2e-17 63.2 0.2 0.00011 22.4 0.0 3.8 3 0 0 3 3 3 3 Response regulator receiver domain HisKA PF00512.25 GAM40444.1 - 3.8e-06 26.8 0.3 1.4e-05 25.1 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 GAM40444.1 - 0.024 14.4 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EHN PF06441.12 GAM40445.1 - 9e-32 109.7 0.0 1.2e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 GAM40445.1 - 1.3e-05 25.0 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM40445.1 - 0.00075 20.2 0.1 0.0063 17.1 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Proteasome PF00227.26 GAM40446.1 - 3.6e-41 140.7 0.0 4.2e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.8 GAM40447.1 - 4.4e-25 87.7 0.2 2.9e-24 85.0 0.0 2.5 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 GAM40447.1 - 0.00013 22.0 0.1 0.00067 19.8 0.0 2.2 2 0 0 2 2 2 1 UBX domain RBD PF02196.15 GAM40447.1 - 0.082 13.0 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 Raf-like Ras-binding domain SRP19 PF01922.17 GAM40447.1 - 0.095 13.7 0.1 17 6.4 0.0 3.1 3 0 0 3 3 3 0 SRP19 protein Ribosomal_L36e PF01158.18 GAM40448.1 - 4.4e-41 139.0 5.9 4.9e-41 138.9 5.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PBS_linker_poly PF00427.21 GAM40448.1 - 0.0025 17.8 0.1 0.0029 17.7 0.1 1.1 1 0 0 1 1 1 1 Phycobilisome Linker polypeptide MRP-L28 PF09812.9 GAM40448.1 - 0.017 15.3 1.8 0.019 15.1 1.8 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 INT_SG_DDX_CT_C PF15300.6 GAM40448.1 - 0.031 14.1 0.4 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus NatB_MDM20 PF09797.9 GAM40449.1 - 9.9e-101 337.4 4.4 9.9e-101 337.4 4.4 1.9 3 0 0 3 3 3 1 N-acetyltransferase B complex (NatB) non catalytic subunit CRCB PF02537.15 GAM40449.1 - 0.0053 17.0 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) TPR_19 PF14559.6 GAM40449.1 - 0.089 13.3 0.3 1.1 9.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat YpjP PF14005.6 GAM40450.1 - 0.11 12.6 0.5 0.67 10.0 0.2 2.2 2 0 0 2 2 2 0 YpjP-like protein zf-C3HC4 PF00097.25 GAM40451.1 - 8.5e-09 35.1 5.3 8.5e-09 35.1 5.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM40451.1 - 4.7e-08 33.2 7.5 4.7e-08 33.2 7.5 2.7 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM40451.1 - 2.1e-07 30.7 6.7 2.1e-07 30.7 6.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAM40451.1 - 7.4e-07 29.2 8.1 7.4e-07 29.2 8.1 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 GAM40451.1 - 1.5e-06 27.9 5.0 1.5e-06 27.9 5.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM40451.1 - 2.5e-06 27.4 6.8 6.7e-06 26.0 6.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAM40451.1 - 1.9e-05 24.5 6.6 1.9e-05 24.5 6.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAM40451.1 - 0.0021 17.9 5.2 0.0021 17.9 5.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAM40451.1 - 0.0058 16.7 1.6 0.0058 16.7 1.6 2.2 3 0 0 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 GAM40451.1 - 0.007 16.2 3.1 0.007 16.2 3.1 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DZR PF12773.7 GAM40451.1 - 0.033 14.2 13.4 0.19 11.8 0.9 2.9 2 1 1 3 3 3 0 Double zinc ribbon Baculo_IE-1 PF05290.11 GAM40451.1 - 0.061 13.3 0.5 0.11 12.4 0.5 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) SAPS PF04499.15 GAM40451.1 - 0.83 8.4 4.9 1.4 7.6 4.9 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein zf-RING_10 PF16685.5 GAM40451.1 - 1.1 9.4 4.2 2.6 8.3 4.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ribbon_3 PF13248.6 GAM40451.1 - 4.6 6.8 8.0 7.1 6.2 3.2 3.0 2 1 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.6 GAM40451.1 - 6.3 6.7 13.6 0.11 12.3 2.6 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain WD40 PF00400.32 GAM40452.1 - 1.1e-19 70.4 6.8 4.3e-06 27.4 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM40452.1 - 0.00082 19.6 0.0 0.03 14.6 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM40452.1 - 0.02 14.2 0.0 0.041 13.2 0.0 1.5 1 1 0 1 1 1 0 WD40-like domain DUF885 PF05960.11 GAM40452.1 - 0.043 13.5 0.5 0.061 13.0 0.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Proteasome PF00227.26 GAM40453.1 - 4.9e-30 104.4 0.0 5.5e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit UCH PF00443.29 GAM40454.1 - 7.6e-25 87.9 0.5 2.7e-24 86.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAM40454.1 - 1.7e-12 47.4 0.8 3.1e-12 46.6 0.2 1.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 GAM40454.1 - 0.00092 18.9 0.0 0.015 15.0 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 GAM40456.1 - 1.4e-54 180.8 9.0 1.1e-06 29.2 0.1 13.3 12 2 0 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.11 GAM40456.1 - 3.1e-48 163.3 0.4 5.8e-48 162.4 0.4 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 GAM40456.1 - 2.8e-13 50.0 0.3 0.088 13.1 0.0 7.3 6 3 0 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM40456.1 - 0.00086 18.4 0.2 0.091 11.7 0.0 3.9 4 1 0 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein G-patch_2 PF12656.7 GAM40457.1 - 8.4e-25 86.6 0.4 4.1e-24 84.4 0.2 2.4 2 0 0 2 2 2 1 G-patch domain G-patch PF01585.23 GAM40457.1 - 0.0002 21.2 0.3 0.00048 20.0 0.3 1.6 1 0 0 1 1 1 1 G-patch domain Kelch_6 PF13964.6 GAM40458.1 - 0.00049 20.3 0.0 0.002 18.3 0.0 2.1 1 0 0 1 1 1 1 Kelch motif NHL PF01436.21 GAM40458.1 - 0.044 13.8 0.4 0.52 10.5 0.0 2.6 2 0 0 2 2 2 0 NHL repeat Kelch_3 PF13415.6 GAM40458.1 - 0.077 13.3 0.3 0.077 13.3 0.3 4.8 4 2 1 5 5 5 0 Galactose oxidase, central domain DUF2624 PF11116.8 GAM40458.1 - 0.15 13.0 0.1 0.27 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) NmrA PF05368.13 GAM40459.1 - 1.7e-17 63.8 0.1 2.4e-17 63.3 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM40459.1 - 1.1e-13 51.6 0.2 2.1e-13 50.6 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM40459.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 GAM40459.1 - 0.00085 19.7 0.2 0.002 18.5 0.2 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAM40459.1 - 0.0036 17.4 0.1 0.0067 16.5 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 GAM40459.1 - 0.014 15.3 0.2 0.026 14.5 0.2 1.4 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.20 GAM40459.1 - 0.016 15.2 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 GAM40459.1 - 0.016 14.3 0.2 0.026 13.6 0.2 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 GAM40459.1 - 0.023 15.3 2.2 0.069 13.7 2.0 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.12 GAM40459.1 - 0.039 13.1 0.2 0.14 11.3 0.0 1.8 1 1 1 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.19 GAM40459.1 - 0.074 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PglD_N PF17836.1 GAM40459.1 - 0.08 13.6 2.5 0.19 12.4 0.3 2.4 3 0 0 3 3 2 0 PglD N-terminal domain LpxI_N PF17930.1 GAM40459.1 - 0.11 12.4 0.1 0.31 10.9 0.1 1.8 1 0 0 1 1 1 0 LpxI N-terminal domain Myb_DNA-bind_6 PF13921.6 GAM40460.1 - 4.5e-16 58.9 0.2 4.5e-16 58.9 0.2 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain HSA PF07529.13 GAM40460.1 - 1.2e-13 51.1 1.5 1.2e-13 51.1 1.5 4.7 5 0 0 5 5 5 1 HSA Myb_DNA-binding PF00249.31 GAM40460.1 - 4.7e-05 23.5 2.3 9.8e-05 22.5 0.3 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain WD40 PF00400.32 GAM40461.1 - 1e-05 26.2 0.1 0.99 10.4 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2_C PF09173.11 GAM40462.1 - 1.3e-34 118.3 0.5 2.8e-34 117.2 0.5 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 GAM40462.1 - 1.1e-23 83.8 0.3 5.3e-23 81.6 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GAM40462.1 - 5.6e-11 42.7 0.1 1.3e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAM40462.1 - 0.0059 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM40462.1 - 0.015 15.2 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 GAM40462.1 - 0.053 12.7 0.1 0.27 10.4 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Peptidase_M48_N PF16491.5 GAM40464.1 - 3.9e-66 222.4 9.3 3.9e-66 222.4 9.3 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 GAM40464.1 - 1.2e-45 155.8 0.1 2.1e-45 154.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 GAM40464.1 - 0.033 13.4 4.0 0.14 11.3 4.0 1.9 1 1 0 1 1 1 0 BlaR1 peptidase M56 DUF4538 PF15061.6 GAM40464.1 - 0.041 13.6 1.7 0.096 12.4 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Peptidase_M16_C PF05193.21 GAM40465.1 - 3.8e-17 62.9 0.0 3.1e-15 56.7 0.0 2.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAM40465.1 - 3e-05 24.0 0.0 9.4e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Sporozoite_P67 PF05642.11 GAM40465.1 - 1.7 6.6 7.0 2.7 6.0 7.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.11 GAM40465.1 - 9.6 6.2 10.0 20 5.2 10.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal WD40 PF00400.32 GAM40466.1 - 3.8e-18 65.5 15.2 8.8e-07 29.5 0.2 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.12 GAM40466.1 - 3.3e-15 56.3 0.4 1.5e-14 54.3 0.0 2.3 2 0 0 2 2 2 1 NLE (NUC135) domain Zw10 PF06248.13 GAM40466.1 - 3.5e-07 29.2 1.3 6.1e-07 28.4 1.3 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 DUF948 PF06103.11 GAM40466.1 - 2.1 8.7 4.2 8 6.8 0.4 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 GAM40466.1 - 2.5 8.8 5.3 64 4.2 0.0 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Merozoite_SPAM PF07133.11 GAM40466.1 - 4.1 7.4 22.3 8 6.4 22.3 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Ribosomal_S13 PF00416.22 GAM40467.1 - 3.7e-18 66.2 0.4 6.3e-16 58.9 0.4 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.21 GAM40468.1 - 2.1e-48 164.6 0.3 2.8e-48 164.2 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.29 GAM40469.1 - 3.3e-49 167.0 0.0 1.1e-48 165.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM40469.1 - 2e-32 111.9 0.0 5.2e-32 110.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM40469.1 - 0.0024 17.9 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAM40469.1 - 0.044 13.1 0.1 0.078 12.3 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 GAM40469.1 - 0.23 10.2 0.0 0.37 9.5 0.0 1.2 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 GAM40469.1 - 0.26 10.4 0.0 0.42 9.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF3883 PF13020.6 GAM40470.1 - 0.11 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) AICARFT_IMPCHas PF01808.18 GAM40472.1 - 1.5e-92 310.2 0.0 2.7e-92 309.4 0.0 1.4 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme INSIG PF07281.12 GAM40472.1 - 1.1e-53 182.0 2.4 1.8e-53 181.3 2.4 1.3 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) MGS PF02142.22 GAM40472.1 - 5.1e-25 87.5 0.0 9.5e-25 86.6 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Dis3l2_C_term PF17877.1 GAM40472.1 - 0.2 12.0 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal Sfi1 PF08457.10 GAM40473.1 - 0.051 12.1 0.4 0.082 11.4 0.4 1.2 1 0 0 1 1 1 0 Sfi1 spindle body protein AATase PF07247.12 GAM40474.1 - 2.9e-20 72.3 0.0 4.4e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Clathrin PF00637.20 GAM40475.1 - 5.8e-196 642.2 45.4 1.6e-32 112.4 0.6 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 GAM40475.1 - 1.6e-33 113.4 0.3 8e-07 29.1 0.0 6.7 6 0 0 6 6 6 4 Clathrin propeller repeat Clathrin_H_link PF13838.6 GAM40475.1 - 1e-32 111.8 1.5 3.5e-32 110.1 0.3 2.7 2 0 0 2 2 2 1 Clathrin-H-link TPR_8 PF13181.6 GAM40475.1 - 0.0011 19.0 3.8 0.37 11.1 0.0 5.0 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM40475.1 - 0.0014 18.5 2.9 39 4.6 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM40475.1 - 0.013 16.2 9.8 11 7.1 0.0 7.9 11 1 0 11 11 7 0 Tetratricopeptide repeat VapB_antitoxin PF09957.9 GAM40475.1 - 0.02 14.8 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB TPR_2 PF07719.17 GAM40475.1 - 0.024 14.8 4.2 7.7 6.9 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Utp13 PF08625.11 GAM40475.1 - 0.047 13.6 5.2 6.5 6.7 0.0 4.8 4 0 0 4 4 4 0 Utp13 specific WD40 associated domain TPR_1 PF00515.28 GAM40475.1 - 0.1 12.5 3.4 6.5 6.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Rop PF01815.16 GAM40475.1 - 0.12 12.2 2.9 0.13 12.2 0.1 2.6 3 0 0 3 3 2 0 Rop protein DUF1400 PF07176.11 GAM40475.1 - 0.14 12.4 7.2 7.6 6.8 0.0 5.0 4 0 0 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF1400) Coatomer_WDAD PF04053.14 GAM40475.1 - 0.18 10.8 10.8 0.17 10.9 0.3 4.1 4 0 0 4 4 4 0 Coatomer WD associated region Vps39_1 PF10366.9 GAM40475.1 - 0.35 11.2 13.7 35 4.7 0.1 6.9 5 2 1 6 6 6 0 Vacuolar sorting protein 39 domain 1 TPR_12 PF13424.6 GAM40475.1 - 3.2 8.1 8.6 37 4.7 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.17 GAM40476.1 - 3.4e-81 271.8 0.1 5.7e-81 271.0 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 GAM40476.1 - 9.9e-71 237.6 0.0 1.7e-70 236.8 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 GAM40476.1 - 1.2e-38 132.0 0.0 2.5e-38 131.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAM40476.1 - 1.1e-30 105.9 0.0 3e-30 104.5 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 GAM40476.1 - 4.6e-27 95.2 0.0 8.6e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 GAM40476.1 - 7.3e-17 61.0 6.4 1.3e-16 60.1 4.6 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 GAM40476.1 - 1.9e-10 40.7 0.0 3.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 GAM40476.1 - 9.9e-10 38.1 2.4 4e-06 26.6 0.2 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.22 GAM40476.1 - 2.3e-07 30.6 0.0 4.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 GAM40476.1 - 7.8e-06 26.0 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 GAM40476.1 - 5.4e-05 22.9 0.1 0.00012 21.8 0.1 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 GAM40476.1 - 0.00074 18.8 0.2 0.026 13.8 0.1 2.3 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 GAM40476.1 - 0.0063 16.1 0.1 0.019 14.6 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 GAM40476.1 - 0.01 15.7 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.6 GAM40476.1 - 0.011 16.5 1.2 5.1 7.8 0.1 3.6 4 0 0 4 4 4 0 HlyD family secretion protein DUF2118 PF09891.9 GAM40476.1 - 0.032 14.2 0.3 0.086 12.8 0.3 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_ST PF14397.6 GAM40476.1 - 0.065 12.5 0.0 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp COesterase PF00135.28 GAM40477.1 - 2.1e-40 139.1 0.0 5.3e-38 131.2 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM40477.1 - 0.0036 17.2 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ribosomal_L5_C PF00673.21 GAM40478.1 - 3.3e-22 78.5 0.0 4.9e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 GAM40478.1 - 2.4e-20 72.6 0.0 7.4e-20 71.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 GAM40479.1 - 7.8e-20 70.3 0.0 9.4e-20 70.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.13 GAM40480.1 - 6.8e-36 122.8 0.0 7.8e-36 122.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 GAM40480.1 - 0.084 12.9 0.2 0.12 12.4 0.2 1.1 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Aa_trans PF01490.18 GAM40481.1 - 3.9e-84 282.7 31.2 4.8e-84 282.4 31.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.21 GAM40482.1 - 1.9e-58 198.2 37.7 2.5e-58 197.9 37.7 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 GAM40482.1 - 1.6e-14 53.8 3.6 1.2e-07 31.1 0.0 3.8 4 0 0 4 4 4 3 Solute carrier family 12 GHMP_kinases_N PF00288.26 GAM40483.1 - 7.2e-16 58.2 0.0 1.7e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAM40483.1 - 7.3e-08 32.7 0.0 1.9e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 GAM40483.1 - 0.0005 19.6 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature SmaI PF17411.2 GAM40483.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease Ovate PF04844.13 GAM40483.1 - 0.19 11.8 0.1 32 4.6 0.0 2.5 2 0 0 2 2 2 0 Transcriptional repressor, ovate Fungal_trans_2 PF11951.8 GAM40484.1 - 7.1e-31 107.4 1.1 3.5e-21 75.5 0.5 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Sulfatase PF00884.23 GAM40485.1 - 5.4e-20 72.0 0.3 9.2e-20 71.2 0.3 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 GAM40485.1 - 3.9e-07 30.0 0.0 6.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 GAM40485.1 - 7.4e-06 24.8 0.2 8.2e-05 21.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF4287 PF14117.6 GAM40485.1 - 0.014 15.6 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) Filament PF00038.21 GAM40485.1 - 0.2 11.2 0.0 2.2 7.8 0.0 2.0 2 0 0 2 2 2 0 Intermediate filament protein PPTA PF01239.22 GAM40486.1 - 8.2e-36 120.7 15.8 2.9e-08 33.2 0.6 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PSCyt2 PF07583.11 GAM40486.1 - 0.026 14.5 0.3 2.3 8.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) DUF4614 PF15391.6 GAM40486.1 - 0.18 11.8 0.1 0.31 11.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF4219 PF13961.6 GAM40486.1 - 8.1 6.2 7.6 26 4.6 0.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) tRNA-synt_1g PF09334.11 GAM40487.1 - 2.2e-94 316.4 1.0 3.6e-93 312.4 1.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAM40487.1 - 2.1e-24 85.8 0.7 7.6e-11 41.0 0.0 3.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 GAM40487.1 - 2.7e-10 40.1 0.0 0.00041 19.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 GAM40487.1 - 2.9e-06 27.3 0.0 7.3e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA NTF2 PF02136.20 GAM40488.1 - 3.5e-08 34.0 0.0 5.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 GAM40488.1 - 8.4e-06 25.8 0.2 5.3e-05 23.2 0.2 1.9 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 DUF4842 PF16130.5 GAM40488.1 - 0.05 13.8 0.2 0.064 13.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4842) Ribosomal_L38e PF01781.18 GAM40489.1 - 1.7e-31 108.1 1.1 2.4e-31 107.6 1.1 1.3 1 0 0 1 1 1 1 Ribosomal L38e protein family DNA_pol_E_B PF04042.16 GAM40490.1 - 7.7e-46 156.1 0.0 1e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 GAM40490.1 - 5.8e-38 129.9 0.0 9.2e-38 129.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Acetyltransf_3 PF13302.7 GAM40490.1 - 5.8e-10 40.0 0.0 1e-09 39.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM40490.1 - 0.027 14.4 0.1 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein NMO PF03060.15 GAM40491.1 - 4.4e-57 194.0 1.3 6.5e-57 193.4 1.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAM40491.1 - 1e-06 28.0 1.9 3.6e-05 22.9 1.9 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAM40491.1 - 0.015 14.4 5.1 0.02 13.9 4.1 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NAD_binding_2 PF03446.15 GAM40491.1 - 0.026 14.7 0.0 0.38 10.9 0.0 2.4 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ATP-synt_I PF03899.15 GAM40491.1 - 0.035 14.5 0.8 0.071 13.5 0.8 1.4 1 0 0 1 1 1 0 ATP synthase I chain CDC48_2 PF02933.17 GAM40491.1 - 0.038 13.8 0.1 0.079 12.8 0.1 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Taxilin PF09728.9 GAM40492.1 - 1e-92 310.6 59.5 1e-92 310.6 59.5 1.6 2 0 0 2 2 2 1 Myosin-like coiled-coil protein ERM PF00769.19 GAM40492.1 - 0.009 15.9 17.5 0.009 15.9 17.5 3.8 2 1 1 4 4 4 1 Ezrin/radixin/moesin family DUF3675 PF12428.8 GAM40492.1 - 0.24 12.0 4.2 5.4 7.6 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) DUF3584 PF12128.8 GAM40492.1 - 1.4 6.3 47.9 2.6 5.5 46.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) GOLGA2L5 PF15070.6 GAM40492.1 - 2 7.0 44.6 0.99 8.0 35.7 2.3 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 zf-C4H2 PF10146.9 GAM40492.1 - 7.8 6.7 38.0 0.85 9.9 8.5 3.3 2 1 1 3 3 3 0 Zinc finger-containing protein EzrA PF06160.12 GAM40492.1 - 9.7 4.2 52.9 0.14 10.3 22.6 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA M16C_assoc PF08367.11 GAM40493.1 - 1.8e-71 240.2 0.0 2.7e-71 239.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 GAM40493.1 - 4.4e-22 79.0 0.0 2.1e-14 54.0 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAM40493.1 - 5.6e-11 42.6 0.0 7.2e-10 39.0 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) adh_short PF00106.25 GAM40494.1 - 1.1e-21 77.2 0.0 1.3e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40494.1 - 9.9e-18 64.5 0.0 1.4e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40494.1 - 0.0038 17.1 0.0 0.0077 16.2 0.0 1.5 1 1 0 1 1 1 1 KR domain Methyltransf_16 PF10294.9 GAM40496.1 - 3.8e-54 183.0 0.1 5.5e-54 182.5 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 GAM40496.1 - 2.3e-05 24.2 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM40496.1 - 0.0002 22.0 0.3 0.00071 20.2 0.3 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM40496.1 - 0.00022 21.1 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM40496.1 - 0.002 17.7 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 GAM40496.1 - 0.022 15.5 0.3 0.075 13.8 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAM40496.1 - 0.13 12.9 0.1 0.35 11.5 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain Orn_Arg_deC_N PF02784.16 GAM40497.1 - 4.9e-81 271.7 0.0 6.2e-81 271.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 GAM40497.1 - 5.6e-18 65.0 0.0 8.8e-18 64.3 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 GAM40497.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel cobW PF02492.19 GAM40498.1 - 1.1e-41 142.4 0.0 1.6e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAM40498.1 - 0.012 15.6 0.0 0.22 11.5 0.0 2.6 3 0 0 3 3 3 0 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 GAM40498.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 GAM40498.1 - 0.023 15.0 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAM40498.1 - 0.038 13.7 0.1 0.45 10.3 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM40498.1 - 0.062 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.12 GAM40498.1 - 0.064 12.7 0.1 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Poxvirus A32 protein SH3_9 PF14604.6 GAM40499.1 - 0.017 15.0 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Hydrolase_4 PF12146.8 GAM40501.1 - 4.2e-06 26.2 0.0 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 GAM40501.1 - 2e-05 24.3 0.0 5.7e-05 22.8 0.0 1.8 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 GAM40501.1 - 2.6e-05 24.0 0.0 4e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM40501.1 - 0.00078 19.0 0.0 0.0078 15.7 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GAM40501.1 - 0.0062 16.2 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 GAM40501.1 - 0.091 11.4 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Mitofilin PF09731.9 GAM40502.1 - 1.2e-157 526.5 31.1 1.2e-127 427.4 35.0 2.3 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Ras PF00071.22 GAM40502.1 - 1.4e-57 193.9 0.4 2.6e-57 193.0 0.4 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM40502.1 - 2.4e-35 121.4 0.1 7.4e-35 119.8 0.1 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM40502.1 - 5.2e-13 48.8 0.1 1e-12 47.9 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM40502.1 - 1e-05 25.0 0.0 3.4e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM40502.1 - 1.4e-05 25.2 0.0 3.9e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Fungal_trans PF04082.18 GAM40502.1 - 2.5e-05 23.4 0.0 6.6e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain GTP_EFTU PF00009.27 GAM40502.1 - 3.7e-05 23.3 1.2 5.2e-05 22.9 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAM40502.1 - 0.0017 18.3 0.1 3 7.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase Cullin PF00888.22 GAM40502.1 - 0.0064 15.2 5.5 0.01 14.5 5.5 1.2 1 0 0 1 1 1 1 Cullin family Lys-AminoMut_A PF09043.11 GAM40502.1 - 0.035 12.6 2.9 0.063 11.7 2.9 1.5 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit AAA_16 PF13191.6 GAM40502.1 - 0.052 13.9 4.8 0.73 10.2 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain Focal_AT PF03623.13 GAM40502.1 - 0.065 13.2 2.3 0.088 12.8 0.3 2.2 1 1 1 2 2 2 0 Focal adhesion targeting region Cas_DxTHG PF09455.10 GAM40502.1 - 6.6 6.2 10.4 1.4 8.4 5.9 2.0 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family VitK2_biosynth PF02621.14 GAM40502.1 - 8.5 5.8 7.8 14 5.1 5.4 2.2 2 0 0 2 2 2 0 Menaquinone biosynthesis Syja_N PF02383.18 GAM40503.1 - 1.3e-91 307.3 0.0 1.7e-91 306.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain ARGLU PF15346.6 GAM40503.1 - 0.18 11.7 1.8 0.3 11.0 1.8 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Mur_ligase_M PF08245.12 GAM40504.1 - 6.3e-05 23.1 4.8 0.0019 18.2 4.8 2.9 1 1 0 1 1 1 1 Mur ligase middle domain Auxin_repressed PF05564.12 GAM40504.1 - 0.23 12.2 0.8 1 10.1 0.1 2.2 2 0 0 2 2 2 0 Dormancy/auxin associated protein NMT_C PF02799.15 GAM40505.1 - 4e-89 297.7 0.0 6.7e-89 296.9 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 GAM40505.1 - 5.9e-75 250.5 0.3 9.7e-74 246.5 0.0 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 GAM40505.1 - 1.5e-05 25.1 0.1 0.00027 21.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM40505.1 - 0.00074 19.7 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family NTP_transf_9 PF04248.12 GAM40505.1 - 0.0095 15.8 0.0 0.026 14.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Acetyltransf_10 PF13673.7 GAM40505.1 - 0.076 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF5024 PF16427.5 GAM40505.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5024) TLD PF07534.16 GAM40506.1 - 3.5e-20 72.7 0.0 7e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 GAM40506.1 - 0.055 14.5 0.8 0.26 12.3 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function Abhydrolase_6 PF12697.7 GAM40508.1 - 9.1e-08 33.0 0.1 1.2e-07 32.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM40508.1 - 0.0014 18.0 0.0 0.0063 15.8 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 GAM40508.1 - 0.034 14.0 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 GAM40508.1 - 0.035 13.7 0.1 0.076 12.6 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold RP-C PF03428.13 GAM40508.1 - 0.066 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain EamA PF00892.20 GAM40508.1 - 0.14 12.4 1.4 0.17 12.0 0.3 1.7 2 0 0 2 2 2 0 EamA-like transporter family GTP_EFTU PF00009.27 GAM40509.1 - 2.1e-57 193.8 0.1 3.4e-57 193.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 GAM40509.1 - 5.2e-34 116.2 0.0 1.1e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 GAM40509.1 - 5.2e-34 116.6 0.1 1e-33 115.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 GAM40509.1 - 2.3e-22 78.8 0.0 4.8e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAM40509.1 - 3.4e-13 49.8 0.1 7.5e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ribosomal_L36 PF00444.18 GAM40509.1 - 1.1e-09 38.4 2.7 2.9e-09 37.0 2.7 1.7 1 0 0 1 1 1 1 Ribosomal protein L36 RF3_C PF16658.5 GAM40509.1 - 8.4e-07 28.9 0.1 2.5e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain ATP_bind_1 PF03029.17 GAM40509.1 - 0.014 15.2 0.1 0.041 13.7 0.1 1.8 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF442 PF04273.13 GAM40509.1 - 0.056 13.5 0.0 0.62 10.2 0.0 2.5 2 0 0 2 2 2 0 Putative phosphatase (DUF442) MMR_HSR1 PF01926.23 GAM40509.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase PALP PF00291.25 GAM40510.1 - 1.7e-77 260.8 0.4 2.2e-77 260.4 0.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 GAM40510.1 - 5.2e-42 141.5 0.0 5.1e-21 74.2 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Zn_clus PF00172.18 GAM40511.1 - 3.9e-08 33.3 11.2 6.9e-08 32.5 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HIG_1_N PF04588.13 GAM40512.1 - 6.1e-24 84.0 0.1 9.2e-24 83.4 0.1 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Metallophos PF00149.28 GAM40514.1 - 1.5e-37 130.1 0.1 2.3e-37 129.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAM40514.1 - 3.2e-16 59.5 0.1 6.2e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain LSM PF01423.22 GAM40515.1 - 1.3e-08 34.4 0.0 1.8e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAM40515.1 - 0.00026 21.0 0.0 0.00037 20.6 0.0 1.5 1 1 0 1 1 1 1 Ataxin 2 SM domain CooC_C PF15976.5 GAM40515.1 - 0.089 12.9 0.0 0.22 11.6 0.0 1.6 2 0 0 2 2 2 0 CS1-pili formation C-terminal Glyco_hydro_11 PF00457.17 GAM40517.1 - 2.1e-65 219.7 11.3 2.1e-65 219.7 11.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 GAM40517.1 - 7.2e-15 54.6 14.0 2.8e-14 52.8 14.0 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 GAM40517.1 - 0.84 9.9 3.4 1.6 9.0 3.4 1.4 1 0 0 1 1 1 0 Toxin 7 Memo PF01875.17 GAM40518.1 - 7e-53 179.5 0.0 3.2e-52 177.3 0.0 1.8 1 1 0 1 1 1 1 Memo-like protein WD40 PF00400.32 GAM40520.1 - 1.1e-12 48.2 1.0 0.15 13.0 0.0 7.8 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM40520.1 - 6.6e-08 32.8 0.0 0.022 15.0 0.0 5.9 5 1 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 GAM40520.1 - 0.0006 19.5 0.4 0.023 14.3 0.9 3.1 3 1 0 3 3 3 1 PQQ-like domain Cyclin_N PF00134.23 GAM40521.1 - 1.5e-35 121.7 0.3 3.5e-35 120.5 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAM40521.1 - 9.9e-12 45.0 0.8 3e-11 43.4 0.2 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain Abhydrolase_3 PF07859.13 GAM40522.1 - 9.1e-45 153.1 0.0 1.2e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAM40522.1 - 1e-05 24.7 0.1 1.9e-05 23.8 0.0 1.3 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 GAM40522.1 - 2e-05 25.3 0.3 3e-05 24.7 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Epimerase PF01370.21 GAM40523.1 - 3.8e-20 72.4 0.0 5.7e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM40523.1 - 4.8e-14 52.0 0.0 6e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM40523.1 - 3.2e-11 43.2 0.0 1.1e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAM40523.1 - 1.5e-09 38.0 0.0 3.4e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 GAM40523.1 - 2.9e-08 33.2 0.0 4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 GAM40523.1 - 1e-05 25.3 0.0 2.9e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family Asp_Glu_race PF01177.22 GAM40523.1 - 0.02 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase adh_short PF00106.25 GAM40523.1 - 0.062 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Glyco_transf_34 PF05637.12 GAM40524.1 - 2.1e-10 40.8 0.0 1.5e-05 24.9 0.0 2.4 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family FmdA_AmdA PF03069.15 GAM40525.1 - 1.2e-54 185.7 0.0 1.4e-30 106.4 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family Beta-lactamase PF00144.24 GAM40526.1 - 2e-30 106.2 0.0 3.1e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 GAM40526.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase UvrD-helicase PF00580.21 GAM40527.1 - 4.7e-61 207.0 0.1 1e-59 202.6 0.1 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 GAM40527.1 - 3.5e-59 201.0 0.0 6.3e-57 193.5 0.0 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 GAM40527.1 - 1.4e-29 103.3 0.3 3.6e-29 102.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 GAM40527.1 - 1.4e-14 53.7 1.4 1.7e-14 53.3 0.1 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 GAM40527.1 - 4.8e-07 29.7 0.0 0.00073 19.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 GAM40527.1 - 5.4e-05 22.9 0.0 0.0014 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 GAM40527.1 - 0.00025 20.9 0.5 0.84 9.3 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 GAM40527.1 - 0.002 17.9 0.1 0.0093 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAM40527.1 - 0.077 13.3 0.6 3.2 8.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain zf-MYND PF01753.18 GAM40528.1 - 1.2e-10 41.3 13.6 2e-10 40.6 13.6 1.4 1 0 0 1 1 1 1 MYND finger ADH_zinc_N_2 PF13602.6 GAM40528.1 - 1.5e-09 39.0 0.0 3.5e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM40528.1 - 7.4e-06 25.8 0.9 1.8e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain zf-C6H2 PF15801.5 GAM40528.1 - 0.041 14.2 10.7 0.12 12.7 10.7 1.8 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Ecl1 PF12855.7 GAM40528.1 - 0.051 14.7 9.7 0.12 13.5 4.3 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Rhodanese_C PF12368.8 GAM40528.1 - 0.44 10.9 4.5 0.83 10.1 4.5 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal zf-C2HC5 PF06221.13 GAM40528.1 - 1.6 8.8 5.7 2.9 7.9 5.7 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type COesterase PF00135.28 GAM40529.1 - 2.4e-95 320.4 0.3 1.1e-81 275.3 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM40529.1 - 0.00015 21.7 0.1 0.00045 20.1 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_3_C PF01915.22 GAM40530.1 - 1.6e-52 178.5 0.2 5e-52 176.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAM40530.1 - 5.9e-40 137.6 0.0 1e-39 136.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM40530.1 - 5.7e-27 93.6 0.0 1.6e-26 92.2 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III-like domain NAD_binding_10 PF13460.6 GAM40530.1 - 1.4e-05 25.1 0.0 3.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding CBM_1 PF00734.18 GAM40530.1 - 0.00038 20.3 7.3 0.00038 20.3 7.3 2.8 3 0 0 3 3 3 1 Fungal cellulose binding domain NmrA PF05368.13 GAM40530.1 - 0.0036 16.9 0.0 0.0086 15.7 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family DUF3708 PF12501.8 GAM40530.1 - 0.12 12.1 0.3 0.45 10.3 0.3 1.9 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Tom37 PF10568.9 GAM40531.1 - 3.3e-38 130.8 0.2 5.9e-38 130.0 0.2 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 GAM40531.1 - 1.9e-12 46.7 0.1 6.4e-11 41.9 0.0 3.1 4 0 0 4 4 4 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GAM40531.1 - 0.00033 21.3 0.0 0.00071 20.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 GAM40531.1 - 0.0038 17.2 0.0 0.023 14.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Zip PF02535.22 GAM40532.1 - 9.7e-65 219.0 5.0 1.1e-64 218.8 5.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Sulfatase PF00884.23 GAM40533.1 - 8.9e-18 64.7 0.3 3.2e-17 62.9 0.3 1.9 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 GAM40533.1 - 0.0036 17.0 0.0 0.0063 16.2 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 GAM40533.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF229 PF02995.17 GAM40533.1 - 0.054 12.1 0.0 0.084 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF2754 PF10953.8 GAM40533.1 - 2.8 8.3 4.8 1.5 9.1 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) Bac_rhamnosid_C PF17390.2 GAM40534.1 - 3.5e-12 46.0 0.3 7.8e-12 44.8 0.3 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 GAM40534.1 - 3.3e-07 29.9 0.0 5.3e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Laminin_G_3 PF13385.6 GAM40534.1 - 0.031 14.4 0.7 0.09 12.9 0.2 2.0 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily RTA1 PF04479.13 GAM40535.1 - 2.6e-74 249.3 9.4 2.6e-74 249.3 9.4 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF2788 PF10981.8 GAM40535.1 - 7.2 6.7 12.1 0.46 10.5 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2788) RTA1 PF04479.13 GAM40536.1 - 1.7e-75 253.2 8.0 1.7e-75 253.2 8.0 1.5 2 0 0 2 2 2 1 RTA1 like protein Sugar_tr PF00083.24 GAM40537.1 - 3e-11 42.9 2.1 3.4e-11 42.7 2.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM40537.1 - 0.00066 18.7 0.0 0.00066 18.7 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Brr6_like_C_C PF10104.9 GAM40537.1 - 0.053 13.3 0.3 0.086 12.6 0.3 1.3 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Glyco_transf_28 PF03033.20 GAM40538.1 - 4.2e-18 65.7 0.0 1.5e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 GAM40538.1 - 0.00012 21.0 0.0 0.00029 19.8 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Abhydrolase_6 PF12697.7 GAM40539.1 - 0.0023 18.6 0.0 0.0036 17.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 GAM40539.1 - 0.006 16.5 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 GAM40539.1 - 0.0069 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAM40539.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 GAM40539.1 - 0.049 13.1 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Thioesterase PF00975.20 GAM40539.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Aldo_ket_red PF00248.21 GAM40540.1 - 1.9e-48 165.2 0.0 2.4e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 GAM40541.1 - 6.1e-05 22.2 0.1 0.0001 21.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain KCNQC3-Ank-G_bd PF11956.8 GAM40541.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 p450 PF00067.22 GAM40542.1 - 4.1e-58 197.2 0.1 9.7e-58 196.0 0.1 1.5 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 GAM40543.1 - 0.011 14.6 5.1 0.011 14.6 5.1 2.2 3 0 0 3 3 3 0 Major Facilitator Superfamily adh_short PF00106.25 GAM40544.1 - 2.4e-26 92.4 0.0 3.2e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40544.1 - 1.3e-16 60.8 0.0 2.7e-16 59.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40544.1 - 3.2e-10 40.2 0.1 7.6e-10 39.0 0.1 1.5 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GAM40544.1 - 0.00059 19.1 0.0 0.0017 17.6 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAM40544.1 - 0.0016 17.9 0.0 0.003 17.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.13 GAM40544.1 - 0.0061 16.5 0.0 0.051 13.5 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family Eno-Rase_NADH_b PF12242.8 GAM40544.1 - 0.11 12.2 0.1 0.36 10.6 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sugar_tr PF00083.24 GAM40547.1 - 4.7e-54 184.0 27.8 6.4e-52 176.9 27.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM40547.1 - 4.5e-18 65.3 34.4 2e-10 40.2 10.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM40547.1 - 0.047 12.3 23.0 0.17 10.4 0.2 3.6 3 1 1 4 4 4 0 MFS/sugar transport protein DUF1304 PF06993.12 GAM40547.1 - 4.6 7.3 7.0 40 4.3 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1304) LIP PF03583.14 GAM40548.1 - 5e-56 190.1 0.2 7.2e-56 189.6 0.2 1.2 1 0 0 1 1 1 1 Secretory lipase Glyco_tran_WecB PF03808.13 GAM40548.1 - 0.18 11.8 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family MFS_1 PF07690.16 GAM40549.1 - 1.3e-24 86.8 57.0 2.5e-23 82.6 21.0 3.5 3 1 1 4 4 4 3 Major Facilitator Superfamily PP2C PF00481.21 GAM40550.1 - 3.4e-40 138.3 0.0 3.8e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAM40550.1 - 8e-07 28.9 0.0 4.8e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAM40550.1 - 5e-05 23.3 0.0 0.087 12.7 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Cyt-b5 PF00173.28 GAM40551.1 - 4.1e-14 52.5 0.0 6e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SPRR2 PF14820.6 GAM40551.1 - 5.6 7.1 16.8 3.2 7.9 13.5 2.3 1 1 1 2 2 2 0 Small proline-rich 2 SPX PF03105.19 GAM40551.1 - 6.2 6.6 10.2 7.8 6.3 10.2 1.2 1 0 0 1 1 1 0 SPX domain FKBP_C PF00254.28 GAM40552.1 - 5.6e-34 116.3 0.0 6.9e-34 116.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Methyltransf_21 PF05050.12 GAM40553.1 - 2.3e-15 57.0 0.0 6e-15 55.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase FkbM domain Met_10 PF02475.16 GAM40553.1 - 0.007 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein V_cholerae_RfbT PF05575.11 GAM40553.1 - 0.075 12.3 0.0 2.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Vibrio cholerae RfbT protein Pex24p PF06398.11 GAM40554.1 - 1.3e-98 330.4 0.4 1.9e-98 329.8 0.4 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Fungal_trans PF04082.18 GAM40555.1 - 8.4e-18 64.4 0.0 1.4e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40555.1 - 3.8e-09 36.5 6.0 1.1e-08 35.1 6.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 GAM40556.1 - 1.8e-36 125.8 55.4 5.4e-36 124.2 55.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM40556.1 - 0.00079 18.0 26.7 0.0014 17.2 26.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPIP1 PF15338.6 GAM40556.1 - 0.1 12.6 3.2 0.31 11.1 0.2 2.4 2 0 0 2 2 2 0 p53-regulated apoptosis-inducing protein 1 DUF983 PF06170.12 GAM40556.1 - 2.7 8.5 13.0 6.1 7.3 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Hemerythrin PF01814.23 GAM40557.1 - 2.1e-08 34.9 0.2 2.9e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain BetaGal_dom3 PF13363.6 GAM40558.1 - 6.7e-07 28.8 0.0 9.6e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 BetaGal_dom4_5 PF13364.6 GAM40559.1 - 4.8e-09 36.8 0.0 4.3e-08 33.7 0.0 2.2 1 1 1 2 2 2 1 Beta-galactosidase jelly roll domain MFS_1 PF07690.16 GAM40560.1 - 2.3e-36 125.5 22.7 6.4e-36 124.0 23.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Leucyl-specific PF14795.6 GAM40560.1 - 0.096 12.8 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain DUF2070 PF09843.9 GAM40560.1 - 0.42 8.8 9.7 0.038 12.3 2.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF1275 PF06912.11 GAM40560.1 - 1.2 9.0 16.6 0.61 10.0 0.8 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1275) DAO PF01266.24 GAM40561.1 - 1.6e-46 159.6 0.0 1.8e-46 159.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM40561.1 - 0.00012 22.2 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAM40561.1 - 0.00032 20.7 0.1 0.12 12.4 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAM40561.1 - 0.00081 18.7 0.2 0.011 14.9 0.1 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM40561.1 - 0.0016 17.7 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 GAM40561.1 - 0.0019 17.4 0.2 0.013 14.6 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 GAM40561.1 - 0.0023 17.3 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM40561.1 - 0.0076 15.3 0.1 0.037 13.1 0.0 1.8 1 1 1 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 GAM40561.1 - 0.026 13.2 0.0 1 8.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Hydrolase PF00702.26 GAM40562.1 - 4.8e-09 36.8 0.0 1.2e-08 35.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAM40562.1 - 4.1e-06 27.0 0.0 6.4e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 GAM40562.1 - 0.068 13.3 0.0 0.87 9.7 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 GAM40563.1 - 4.7e-06 25.8 0.5 1e-05 24.7 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40564.1 - 0.016 15.3 0.3 0.035 14.2 0.3 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 GAM40565.1 - 5.4e-34 117.4 0.3 9e-34 116.6 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40565.1 - 1.8e-27 96.4 0.3 4.1e-27 95.3 0.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40565.1 - 8e-10 38.9 2.8 1.2e-08 35.1 0.8 2.2 2 0 0 2 2 2 1 KR domain AAT PF03417.16 GAM40565.1 - 4.2e-05 23.4 0.0 0.00023 21.0 0.0 2.1 1 1 1 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Polysacc_synt_2 PF02719.15 GAM40565.1 - 0.0014 17.8 0.3 0.002 17.3 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 GAM40565.1 - 0.031 14.1 1.0 0.089 12.7 0.6 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 GAM40565.1 - 0.089 12.8 0.3 0.22 11.5 0.3 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1776 PF08643.10 GAM40565.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) p450 PF00067.22 GAM40566.1 - 1.6e-40 139.2 0.1 1.1e-39 136.5 0.1 1.8 1 1 0 1 1 1 1 Cytochrome P450 Amidohydro_3 PF07969.11 GAM40567.1 - 3.1e-06 27.0 0.1 4.4e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Ank_4 PF13637.6 GAM40567.1 - 6.7e-05 23.4 0.0 0.094 13.3 0.0 3.3 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM40567.1 - 0.00012 22.6 0.0 0.00054 20.5 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAM40567.1 - 0.0075 16.7 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 GAM40567.1 - 0.037 14.6 0.0 1.4e+02 3.6 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeat Amidohydro_1 PF01979.20 GAM40567.1 - 0.15 11.3 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Amidohydrolase family Pam16 PF03656.13 GAM40569.1 - 1.8e-33 115.2 0.1 2.2e-33 115.0 0.1 1.0 1 0 0 1 1 1 1 Pam16 YWFCY PF14293.6 GAM40570.1 - 0.27 11.5 1.7 4.9 7.5 0.0 2.9 3 0 0 3 3 3 0 YWFCY protein Aldo_ket_red PF00248.21 GAM40571.1 - 5.4e-54 183.4 0.0 7.3e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_3 PF01596.17 GAM40572.1 - 2e-13 50.0 0.0 2.6e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 GAM40572.1 - 3.6e-10 40.8 0.0 6.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 GAM40572.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Cephalosporin hydroxylase NmrA PF05368.13 GAM40574.1 - 6.7e-54 182.9 1.5 8e-54 182.6 1.5 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM40574.1 - 5.4e-20 72.1 0.3 7.1e-20 71.7 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAM40574.1 - 2.4e-05 23.5 0.0 3.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM40574.1 - 0.0077 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Translat_reg PF01818.17 GAM40574.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage translational regulator Fungal_trans PF04082.18 GAM40575.1 - 1.6e-21 76.6 0.0 3.3e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 GAM40576.1 - 7e-13 48.9 0.0 9.7e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM40576.1 - 2.4e-09 37.0 0.1 3e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM40576.1 - 1.7e-05 24.4 0.0 2.2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAM40576.1 - 0.0016 18.1 0.9 0.0024 17.5 0.9 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 GAM40576.1 - 0.0023 17.1 0.1 0.0032 16.6 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.18 GAM40576.1 - 0.0026 18.0 0.1 0.0038 17.5 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.24 GAM40576.1 - 0.014 15.8 0.2 0.023 15.1 0.2 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAM40576.1 - 0.088 12.9 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Hemerythrin PF01814.23 GAM40577.1 - 6.2e-09 36.6 0.2 1e-08 35.9 0.2 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Glutaredoxin2_C PF04399.13 GAM40578.1 - 0.12 12.3 1.8 9.7 6.0 0.0 2.5 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Spc7 PF08317.11 GAM40578.1 - 0.95 8.3 19.2 1.5 7.6 19.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 GAM40578.1 - 7.3 6.7 24.6 13 5.8 24.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Dabb PF07876.12 GAM40579.1 - 2.2e-24 85.9 0.1 2.5e-24 85.7 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF4390 PF14334.6 GAM40579.1 - 0.07 12.6 0.0 0.093 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) FAA_hydrolase PF01557.18 GAM40580.1 - 1.8e-54 184.7 0.0 2.5e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Tnp_P_element_C PF12596.8 GAM40580.1 - 0.087 13.4 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 87kDa Transposase B12-binding PF02310.19 GAM40581.1 - 0.0023 18.0 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 B12 binding domain FtsK_SpoIIIE PF01580.18 GAM40581.1 - 0.061 12.7 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Abhydrolase_1 PF00561.20 GAM40582.1 - 1.4e-19 70.7 0.0 6.1e-17 62.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM40582.1 - 3.8e-14 53.8 0.0 5.2e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM40582.1 - 1.4e-09 37.6 0.1 2.8e-09 36.6 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAM40582.1 - 4.3e-06 27.0 0.0 5.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF915 PF06028.11 GAM40582.1 - 0.00013 21.4 0.1 0.059 12.7 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 GAM40582.1 - 0.00014 21.7 0.6 0.031 14.0 0.6 2.2 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 GAM40582.1 - 0.00022 21.0 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF676 PF05057.14 GAM40582.1 - 0.00056 19.5 0.0 0.00092 18.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 GAM40582.1 - 0.0016 17.4 0.2 0.005 15.8 0.3 1.8 2 1 0 2 2 2 1 Chlorophyllase enzyme Palm_thioest PF02089.15 GAM40582.1 - 0.0017 18.3 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_3 PF07859.13 GAM40582.1 - 0.0026 17.7 0.0 0.0052 16.7 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 GAM40582.1 - 0.013 14.6 0.0 0.032 13.3 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase Ndr PF03096.14 GAM40582.1 - 0.015 14.0 0.0 0.022 13.5 0.0 1.5 1 1 0 1 1 1 0 Ndr family DUF2048 PF09752.9 GAM40582.1 - 0.016 14.3 0.0 0.088 11.9 0.0 1.9 1 1 0 1 1 1 0 Abhydrolase domain containing 18 Lipase_3 PF01764.25 GAM40582.1 - 0.025 14.4 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) AAA_13 PF13166.6 GAM40583.1 - 0.00012 20.9 15.2 0.00012 20.9 15.2 3.5 2 1 2 4 4 4 1 AAA domain MscS_porin PF12795.7 GAM40583.1 - 0.0017 17.9 24.2 0.0017 17.9 24.2 4.9 3 2 2 5 5 5 1 Mechanosensitive ion channel porin domain HSBP1 PF06825.12 GAM40583.1 - 0.0094 15.8 4.3 1.9 8.4 0.1 3.9 3 0 0 3 3 3 2 Heat shock factor binding protein 1 DUF3877 PF12993.7 GAM40583.1 - 5.4 6.9 10.0 0.37 10.6 0.6 3.3 3 1 0 3 3 3 0 Domain of unknown function, E. rectale Gene description (DUF3877) TIP49 PF06068.13 GAM40584.1 - 8.1e-151 502.2 1.0 8.1e-151 502.2 1.0 1.3 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 GAM40584.1 - 3.4e-22 78.4 0.6 1.3e-21 76.5 0.3 2.2 2 0 0 2 2 2 1 TIP49 AAA-lid domain RuvB_N PF05496.12 GAM40584.1 - 2.2e-08 34.0 0.5 2.7e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 GAM40584.1 - 3.3e-08 34.0 1.2 4.9e-05 23.8 0.1 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM40584.1 - 1.1e-06 29.1 0.5 4.3e-06 27.2 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain DnaB_C PF03796.15 GAM40584.1 - 1.8e-05 24.2 0.6 3.6e-05 23.2 0.6 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 GAM40584.1 - 0.0045 16.4 0.7 0.051 12.9 0.4 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 GAM40584.1 - 0.0058 16.3 0.0 3.6 7.3 0.1 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 GAM40584.1 - 0.013 15.9 1.6 0.21 11.9 1.6 2.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAM40584.1 - 0.03 13.9 0.3 0.063 12.8 0.3 1.5 1 0 0 1 1 1 0 AAA domain TFIID-31kDa PF02291.15 GAM40584.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit AAA_33 PF13671.6 GAM40584.1 - 0.07 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAM40584.1 - 0.07 13.1 0.2 2.6 8.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 GAM40584.1 - 0.082 12.7 0.1 0.19 11.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM40584.1 - 0.098 12.2 0.3 0.73 9.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Hydin_ADK PF17213.3 GAM40584.1 - 0.11 12.7 0.6 0.26 11.6 0.2 1.7 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA_28 PF13521.6 GAM40584.1 - 0.15 12.3 0.1 0.32 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain GYF PF02213.16 GAM40585.1 - 2.1e-13 49.7 2.1 6.8e-13 48.1 2.1 1.9 1 0 0 1 1 1 1 GYF domain UFD1 PF03152.14 GAM40586.1 - 1.2e-75 252.8 0.0 1.4e-75 252.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF829 PF05705.14 GAM40587.1 - 8.1e-42 143.8 0.5 3.7e-41 141.6 0.5 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Ank_2 PF12796.7 GAM40588.1 - 2.6e-08 34.3 0.1 0.008 16.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM40588.1 - 3.8e-08 33.7 0.1 0.11 13.1 0.0 3.9 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM40588.1 - 5.8e-06 26.5 0.4 0.0011 19.2 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM40588.1 - 1.1e-05 25.4 2.5 0.0091 16.4 0.0 3.9 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 GAM40588.1 - 0.0042 17.5 0.7 1.1 9.8 0.0 3.4 4 1 0 4 4 4 1 Ankyrin repeat Helicase_PWI PF18149.1 GAM40588.1 - 0.14 12.3 0.1 0.31 11.2 0.0 1.6 1 1 1 2 2 2 0 N-terminal helicase PWI domain DUF4246 PF14033.6 GAM40589.1 - 1.7e-133 446.0 0.1 2.1e-133 445.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF4996 PF16387.5 GAM40589.1 - 0.052 14.0 0.0 0.16 12.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function Rod_cone_degen PF15201.6 GAM40589.1 - 0.22 11.7 1.1 0.44 10.7 1.1 1.4 1 0 0 1 1 1 0 Progressive rod-cone degeneration RNA_pol_Rpb2_6 PF00562.28 GAM40590.1 - 2.7e-123 411.9 0.4 4e-123 411.4 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAM40590.1 - 1.1e-55 188.3 0.6 1.7e-55 187.7 0.6 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 GAM40590.1 - 5.7e-32 110.0 0.4 1.3e-31 108.8 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 GAM40590.1 - 1.5e-27 96.5 2.4 6e-27 94.5 2.9 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 GAM40590.1 - 2.9e-24 85.1 0.3 6.8e-24 83.9 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 GAM40590.1 - 2.6e-19 69.1 0.0 5.6e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 GAM40590.1 - 1e-09 38.8 2.5 4.5e-09 36.7 2.5 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 zn-ribbon_14 PF16503.5 GAM40590.1 - 6 6.5 6.7 0.53 9.8 2.0 1.8 2 0 0 2 2 2 0 Zinc-ribbon PUF PF00806.19 GAM40591.1 - 3e-57 187.2 7.3 5.7e-08 32.0 0.0 8.7 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Nup88 PF10168.9 GAM40591.1 - 0.095 10.5 0.3 0.14 10.0 0.3 1.1 1 0 0 1 1 1 0 Nuclear pore component RHH_3 PF12651.7 GAM40591.1 - 0.17 11.9 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix domain ORC5_C PF14630.6 GAM40592.1 - 5e-83 278.9 0.0 6.6e-83 278.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 GAM40592.1 - 4.7e-19 69.4 0.1 8.3e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain GFA PF04828.14 GAM40593.1 - 5.6e-13 49.1 0.8 5.6e-13 49.1 0.8 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Orthopox_A5L PF06193.11 GAM40593.1 - 0.18 11.2 3.7 0.24 10.8 3.7 1.1 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like adh_short PF00106.25 GAM40594.1 - 1.1e-23 83.8 0.0 3.5e-18 65.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40594.1 - 8.8e-11 41.8 0.1 9.6e-09 35.1 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40594.1 - 1.8e-05 24.7 0.0 2.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 KR domain E1-E2_ATPase PF00122.20 GAM40595.1 - 1.1e-44 152.1 4.8 1.1e-44 152.1 4.8 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAM40595.1 - 4.5e-16 59.8 0.1 1.1e-15 58.5 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM40595.1 - 3.1e-11 42.8 0.0 6.3e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAM40595.1 - 0.00069 19.7 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAM40595.1 - 0.012 15.4 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase EF-hand_4 PF12763.7 GAM40596.1 - 5e-39 132.4 0.0 7.3e-16 58.0 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 GAM40596.1 - 4.4e-08 32.9 0.0 8.5e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.6 GAM40596.1 - 4.6e-07 30.2 0.0 0.0042 17.5 0.0 3.9 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 GAM40596.1 - 1.4e-06 27.4 0.1 0.0022 17.4 0.0 4.2 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.6 GAM40596.1 - 0.0004 20.1 0.8 0.59 10.2 0.0 4.6 5 0 0 5 5 5 1 EF-hand domain EF-hand_8 PF13833.6 GAM40596.1 - 0.0013 18.6 0.2 0.62 9.9 0.1 4.1 4 1 1 5 5 5 1 EF-hand domain pair Spc7 PF08317.11 GAM40596.1 - 0.0031 16.5 33.7 0.027 13.3 20.2 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein GAS PF13851.6 GAM40596.1 - 0.11 11.8 29.1 0.096 12.0 12.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 GAM40596.1 - 0.69 10.0 39.9 0.35 10.9 7.1 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 GAM40596.1 - 1.3 8.0 19.5 2.5 7.1 19.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tubulin PF00091.25 GAM40597.1 - 7.6e-67 225.3 0.0 1.2e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAM40597.1 - 7.1e-50 168.4 0.1 1.3e-49 167.6 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAM40597.1 - 0.0012 18.5 0.0 0.0029 17.3 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain RNA_pol_Rpc82 PF05645.13 GAM40599.1 - 5.7e-27 95.1 0.5 4.1e-26 92.3 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 GAM40599.1 - 2.2e-15 56.5 5.0 3.5e-10 39.8 0.2 3.4 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 GAM40599.1 - 1.2e-10 41.2 0.5 0.00023 21.0 0.1 2.9 2 0 0 2 2 2 2 TFIIE alpha subunit TrmB PF01978.19 GAM40599.1 - 0.00012 21.9 0.3 0.5 10.3 0.0 3.3 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB ANAPC2 PF08672.11 GAM40599.1 - 0.038 14.5 1.2 17 6.0 0.3 4.0 4 0 0 4 4 4 0 Anaphase promoting complex (APC) subunit 2 SMC_ScpB PF04079.16 GAM40599.1 - 0.08 12.6 2.3 0.85 9.2 0.1 3.0 3 0 0 3 3 3 0 Segregation and condensation complex subunit ScpB PCB_OB PF17092.5 GAM40599.1 - 0.11 13.2 0.1 0.33 11.7 0.1 1.7 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain HxlR PF01638.17 GAM40599.1 - 0.55 10.1 2.8 7.4 6.5 0.2 3.2 2 1 1 3 3 3 0 HxlR-like helix-turn-helix Peptidase_M16 PF00675.20 GAM40600.1 - 3.7e-16 59.4 0.2 5.9e-16 58.8 0.2 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAM40600.1 - 8.9e-12 45.4 0.0 1.7e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF1107 PF06526.12 GAM40600.1 - 0.029 14.3 0.0 4.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1107) BCS1_N PF08740.11 GAM40600.1 - 0.085 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 BCS1 N terminal Pkinase PF00069.25 GAM40601.1 - 5.4e-15 55.5 0.0 6.8e-14 51.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM40601.1 - 3.1e-07 30.0 0.0 0.00017 21.0 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Mito_carr PF00153.27 GAM40602.1 - 1e-27 95.9 2.3 6.5e-12 45.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.21 GAM40603.1 - 3.8e-102 342.0 0.0 4.8e-102 341.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 GAM40603.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Arylsulfotran_2 PF14269.6 GAM40604.1 - 6.5e-58 196.5 1.7 9.3e-58 195.9 1.7 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 GAM40604.1 - 7.3e-14 51.5 0.1 1.4e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) CTD_bind PF04818.13 GAM40604.1 - 3.4e-09 37.4 0.0 7e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 GAM40604.1 - 2.5e-05 24.0 0.0 4.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cys_Met_Meta_PP PF01053.20 GAM40605.1 - 4.7e-151 502.7 0.0 5.3e-151 502.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 GAM40605.1 - 1.2e-10 41.2 0.8 1.2e-10 41.2 0.8 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 GAM40605.1 - 5.9e-08 32.3 0.1 1.8e-07 30.7 0.1 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GAM40605.1 - 1.5e-06 27.4 0.6 2.8e-06 26.5 0.6 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAM40605.1 - 1.4e-05 24.6 0.0 2.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 GAM40605.1 - 0.0068 15.0 0.0 0.0099 14.4 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 GAM40605.1 - 0.0093 14.8 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Asparaginase_C PF17763.1 GAM40605.1 - 0.04 14.1 0.0 0.18 12.0 0.0 2.0 1 1 1 2 2 2 0 Glutaminase/Asparaginase C-terminal domain SepSecS PF05889.13 GAM40605.1 - 0.13 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS MARVEL PF01284.23 GAM40606.1 - 2.6e-20 72.9 17.8 3.3e-20 72.6 17.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain AA_permease PF00324.21 GAM40607.1 - 2.2e-133 445.4 46.9 2.6e-133 445.1 46.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM40607.1 - 4.1e-31 108.3 52.0 5e-31 108.0 52.0 1.1 1 0 0 1 1 1 1 Amino acid permease 2-Hacid_dh_C PF02826.19 GAM40608.1 - 4.5e-42 143.4 0.0 3.9e-30 104.5 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAM40608.1 - 0.0054 16.9 0.0 0.01 16.0 0.0 1.4 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 GAM40608.1 - 0.022 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 GAM40608.1 - 0.04 14.4 0.0 0.075 13.5 0.0 1.4 1 1 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.18 GAM40608.1 - 0.096 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GAM40608.1 - 0.12 13.0 0.0 0.26 11.9 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3870 PF12986.7 GAM40608.1 - 0.16 12.2 0.1 0.33 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) AMP-binding PF00501.28 GAM40609.1 - 1.8e-82 277.2 0.0 2.4e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2012 PF09430.10 GAM40610.1 - 3.8e-33 114.2 0.0 5.1e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Peptidase_M24 PF00557.24 GAM40611.1 - 5.1e-18 65.5 0.0 7.1e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Ank_2 PF12796.7 GAM40612.1 - 7.5e-36 122.6 0.0 1.8e-14 54.1 0.0 4.5 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM40612.1 - 4.2e-28 97.4 0.2 3e-09 37.2 0.3 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM40612.1 - 1.3e-23 80.4 2.1 0.001 19.3 0.0 7.5 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 GAM40612.1 - 2.7e-20 71.9 2.3 0.0066 16.9 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 GAM40612.1 - 4.7e-16 58.7 5.6 0.0077 16.5 0.9 7.1 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Clr5 PF14420.6 GAM40612.1 - 1.7e-15 57.0 0.0 3.3e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Clr5 domain WW PF00397.26 GAM40613.1 - 1.2e-10 41.2 1.0 1.2e-10 41.2 1.0 1.9 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.9 GAM40613.1 - 4e-07 30.3 26.2 4e-07 30.3 26.2 2.7 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) CYSTM PF12734.7 GAM40613.1 - 0.0038 17.5 3.6 0.0038 17.5 3.6 5.7 5 2 0 5 5 5 2 Cysteine-rich TM module stress tolerance SCIMP PF15050.6 GAM40613.1 - 0.13 12.8 0.3 0.22 12.0 0.3 1.4 1 0 0 1 1 1 0 SCIMP protein WD40 PF00400.32 GAM40614.1 - 9.8e-12 45.2 18.6 0.0037 18.1 0.1 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.8 GAM40614.1 - 0.012 14.2 0.1 0.024 13.3 0.1 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Mito_carr PF00153.27 GAM40615.1 - 2e-53 178.3 1.7 2.3e-17 62.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.16 GAM40615.1 - 0.036 14.0 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 UcrQ family HMD PF03201.16 GAM40615.1 - 0.059 13.6 0.1 2.6 8.3 0.0 3.1 3 1 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase PrcB_C PF14343.6 GAM40615.1 - 0.12 12.5 0.0 3.8 7.7 0.0 2.3 2 0 0 2 2 2 0 PrcB C-terminal ERAP1_C PF11838.8 GAM40616.1 - 1e-87 294.6 0.9 1.7e-87 293.9 0.6 1.5 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 GAM40616.1 - 3.1e-83 278.6 2.1 6.3e-83 277.6 2.1 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 GAM40616.1 - 9.9e-39 133.5 0.0 1.1e-37 130.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Ssl1 PF04056.14 GAM40617.1 - 3.6e-32 111.7 0.0 4.7e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 GAM40617.1 - 7.8e-16 58.6 0.0 1.1e-15 58.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF5572 PF17733.1 GAM40618.1 - 2.9e-22 78.2 0.4 2.9e-22 78.2 0.4 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5572) FXR_C3 PF16097.5 GAM40618.1 - 1.7 9.4 9.2 5.1 7.9 5.4 2.4 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 PUF PF00806.19 GAM40619.1 - 1.1e-36 122.4 0.9 6.8e-06 25.5 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat I_LWEQ PF01608.17 GAM40619.1 - 0.16 12.2 1.8 1.9 8.7 1.5 2.2 2 0 0 2 2 2 0 I/LWEQ domain TPT PF03151.16 GAM40620.1 - 4.8e-60 203.4 16.1 5.9e-60 203.1 16.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAM40620.1 - 3.7e-07 30.4 35.9 0.00012 22.2 14.5 2.9 2 1 0 2 2 2 2 EamA-like transporter family Choline_transpo PF04515.12 GAM40622.1 - 3.1e-28 98.9 24.7 3.1e-28 98.9 24.7 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter Ras PF00071.22 GAM40623.1 - 1.9e-48 164.2 0.1 1.5e-38 131.9 0.1 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 GAM40623.1 - 1.6e-29 102.6 0.0 4.4e-19 68.9 0.0 2.3 1 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 GAM40623.1 - 3.5e-09 36.5 0.0 7.2e-09 35.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 GAM40623.1 - 2.7e-08 33.5 0.0 1e-07 31.6 0.1 1.9 2 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM40623.1 - 2.8e-06 26.9 0.0 5.7e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM40623.1 - 2e-05 24.6 0.3 0.0007 19.7 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM40623.1 - 0.005 16.8 0.6 0.89 9.4 0.2 2.4 1 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 GAM40623.1 - 0.097 12.9 0.3 0.37 11.1 0.1 2.2 2 1 0 2 2 2 0 AAA domain Flu_M1_C PF08289.11 GAM40623.1 - 0.14 12.4 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain PMT PF02366.18 GAM40624.1 - 1.3e-87 293.4 15.6 1.3e-87 293.4 15.6 2.0 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAM40624.1 - 8.4e-65 218.1 14.8 8.4e-65 218.1 14.8 2.7 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 GAM40624.1 - 1.5e-35 122.7 1.2 2.4e-35 122.1 1.2 1.2 1 0 0 1 1 1 1 MIR domain Sugar_tr PF00083.24 GAM40625.1 - 1e-102 344.4 10.7 1.3e-102 344.0 10.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM40625.1 - 1.5e-29 103.0 30.8 2.7e-24 85.7 9.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM40625.1 - 6.2e-08 31.6 19.3 2.2e-07 29.8 6.1 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein Mito_carr PF00153.27 GAM40626.1 - 5.4e-19 67.9 1.2 1.9e-12 46.9 0.1 2.8 2 1 0 2 2 2 2 Mitochondrial carrier protein SPT16 PF08644.11 GAM40627.1 - 5e-58 195.6 0.0 1.7e-57 193.9 0.0 2.0 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 GAM40627.1 - 2.4e-55 186.7 0.0 7.5e-55 185.1 0.0 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 GAM40627.1 - 9.5e-26 90.8 0.0 1.5e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 GAM40627.1 - 4.8e-15 55.8 0.3 2.3e-14 53.6 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Peptidase_M43 PF05572.13 GAM40628.1 - 4.4e-13 49.4 0.1 1.2e-12 48.0 0.1 1.7 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAM40628.1 - 0.003 17.7 0.5 0.0073 16.5 0.5 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 GAM40628.1 - 0.081 12.8 0.8 0.15 11.9 0.8 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CDC50 PF03381.15 GAM40629.1 - 2.3e-97 325.9 0.1 2.8e-97 325.6 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3185 PF11381.8 GAM40629.1 - 0.56 10.3 8.0 0.1 12.6 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) SWIRM PF04433.17 GAM40630.1 - 4.3e-11 43.0 0.0 7.8e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain Ribonucleas_3_3 PF14622.6 GAM40631.1 - 1.3e-15 57.7 0.0 6e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 GAM40631.1 - 6.4e-14 52.5 0.0 1.7e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain Epimerase PF01370.21 GAM40632.1 - 9.8e-22 77.6 0.0 1.3e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM40632.1 - 2.5e-16 59.5 0.0 3.9e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAM40632.1 - 1e-09 38.6 0.0 1.6e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAM40632.1 - 1.3e-08 34.7 0.4 6.2e-08 32.4 0.0 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAM40632.1 - 2.7e-08 33.7 0.2 2.3e-06 27.3 0.1 2.2 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 GAM40632.1 - 1e-06 28.4 0.0 7.7e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 GAM40632.1 - 7.1e-06 25.4 0.0 0.059 12.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 GAM40632.1 - 0.001 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAM40632.1 - 0.014 15.3 0.1 0.04 13.8 0.1 1.8 1 1 0 1 1 1 0 KR domain adh_short_C2 PF13561.6 GAM40632.1 - 0.073 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 GAM40632.1 - 0.082 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Abhydrolase_1 PF00561.20 GAM40633.1 - 4.2e-09 36.4 0.0 5.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 GAM40633.1 - 0.0068 15.1 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family DUF1100 PF06500.11 GAM40633.1 - 0.054 12.3 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Pectate_lyase_3 PF12708.7 GAM40634.1 - 3.9e-90 301.4 13.7 1e-78 264.1 5.8 3.0 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 GAM40634.1 - 2.5e-06 27.1 3.8 0.018 14.8 0.4 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Kelch_4 PF13418.6 GAM40634.1 - 0.33 11.0 2.3 8.4 6.5 0.0 3.1 3 0 0 3 3 3 0 Galactose oxidase, central domain MFS_1 PF07690.16 GAM40635.1 - 1.9e-22 79.7 62.5 7.1e-19 67.9 35.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2304 PF10066.9 GAM40635.1 - 0.29 11.4 0.1 0.29 11.4 0.1 3.6 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2304) DUF2206 PF09971.9 GAM40636.1 - 9.8 4.8 10.8 1.6 7.4 1.9 2.5 1 1 1 3 3 3 0 Predicted membrane protein (DUF2206) p450 PF00067.22 GAM40638.1 - 7.4e-46 156.8 0.0 8.9e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 GAM40639.1 - 7.2e-15 54.8 0.0 1.1e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 GAM40639.1 - 0.012 16.3 0.0 0.037 14.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAM40639.1 - 0.032 15.0 0.0 0.064 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAM40639.1 - 0.048 13.2 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 GAM40639.1 - 0.14 12.0 0.0 0.62 9.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Cu_bind_like PF02298.17 GAM40640.1 - 0.00073 19.5 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Plastocyanin-like domain Helo_like_N PF17111.5 GAM40642.1 - 1.8e-09 37.3 4.2 3.9e-08 32.9 0.2 2.6 2 1 0 2 2 2 2 Fungal N-terminal domain of STAND proteins p31comet PF06581.12 GAM40642.1 - 0.79 8.8 2.6 5.1 6.2 0.1 3.1 3 1 1 4 4 4 0 Mad1 and Cdc20-bound-Mad2 binding Ferric_reduct PF01794.19 GAM40643.1 - 1.4e-20 73.7 20.1 2.5e-20 72.8 16.0 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAM40643.1 - 2.8e-13 50.3 0.0 6.3e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAM40643.1 - 5.9e-08 32.8 0.0 0.0031 17.6 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain FliM PF02154.15 GAM40643.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM NAD_binding_1 PF00175.21 GAM40643.1 - 0.21 12.2 0.0 0.69 10.6 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain PDR_CDR PF06422.12 GAM40643.1 - 0.36 10.8 2.5 14 5.7 0.3 2.8 2 0 0 2 2 2 0 CDR ABC transporter DUF382 PF04037.13 GAM40645.1 - 4.5e-59 198.1 0.9 1e-58 197.0 0.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 GAM40645.1 - 1.9e-20 72.4 3.8 3.8e-20 71.5 3.8 1.5 1 0 0 1 1 1 1 PSP ER_lumen_recept PF00810.18 GAM40647.1 - 1.6e-43 149.0 8.1 3.2e-43 148.1 8.1 1.5 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 GAM40647.1 - 0.012 15.4 2.3 1.2 8.9 0.2 2.7 2 0 0 2 2 2 0 PQ loop repeat Vps54 PF07928.12 GAM40650.1 - 0.31 11.5 5.3 0.17 12.3 0.8 2.1 2 0 0 2 2 2 0 Vps54-like protein Baculo_PEP_C PF04513.12 GAM40650.1 - 5.4 7.0 15.9 4.3 7.4 3.8 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus XRCC4 PF06632.12 GAM40650.1 - 5.9 5.7 40.7 0.042 12.7 30.4 2.7 1 1 1 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Molybdopterin PF00384.22 GAM40651.1 - 9.4e-72 242.3 0.0 1.8e-69 234.8 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 GAM40651.1 - 2.7e-20 72.2 0.1 7.2e-20 70.8 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 GAM40651.1 - 4.4e-18 65.7 0.0 1.1e-17 64.5 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 GAM40651.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 GAM40651.1 - 4.9e-09 36.0 0.5 4.9e-09 36.0 0.5 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 GAM40651.1 - 0.086 12.6 0.0 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 GAM40651.1 - 0.12 12.2 1.1 3.5 7.6 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Lyx_isomer PF07385.12 GAM40651.1 - 0.17 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 D-lyxose isomerase Fer4_19 PF06902.11 GAM40651.1 - 0.21 11.7 2.2 4 7.6 2.2 2.6 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_17 PF13534.6 GAM40651.1 - 2.8 8.5 5.4 0.65 10.6 1.4 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Aldo_ket_red PF00248.21 GAM40652.1 - 5.8e-47 160.3 0.2 3.3e-45 154.5 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family PurL_C PF16904.5 GAM40652.1 - 0.13 12.6 0.0 0.64 10.3 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine synthase II C-terminus UPF0061 PF02696.14 GAM40653.1 - 5.4e-109 365.1 0.0 6.5e-108 361.5 0.0 2.0 2 0 0 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family zf-CCHC PF00098.23 GAM40654.1 - 2.3e-53 176.0 65.3 4.9e-09 35.9 1.8 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 GAM40654.1 - 1e-11 44.4 43.1 0.018 14.8 1.3 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 GAM40654.1 - 4.3e-06 26.3 45.2 0.16 11.7 1.3 7.1 5 1 2 7 7 7 7 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 GAM40654.1 - 2.2e-05 24.3 54.1 0.07 13.1 1.6 7.0 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.6 GAM40654.1 - 3.6 7.5 49.8 0.5 10.2 1.6 7.0 6 1 1 7 7 7 0 Zinc knuckle F-box-like PF12937.7 GAM40655.1 - 0.03 14.2 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like SAE2 PF08573.10 GAM40656.1 - 6.7e-33 114.1 0.1 6.7e-33 114.1 0.1 3.4 3 1 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Orbi_NS3 PF01616.16 GAM40656.1 - 0.25 11.0 0.7 0.49 10.1 0.7 1.4 1 0 0 1 1 1 0 Orbivirus NS3 GAS PF13851.6 GAM40656.1 - 0.3 10.4 0.1 0.3 10.4 0.1 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1319 PF07028.11 GAM40656.1 - 0.33 11.2 3.9 0.45 10.8 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) TRAF_BIRC3_bd PF16673.5 GAM40656.1 - 0.56 10.0 3.1 1.1 9.1 1.4 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain SidE PF12252.8 GAM40656.1 - 0.69 7.4 6.0 0.94 6.9 6.0 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein Pex16 PF08610.10 GAM40657.1 - 3.1e-141 470.2 0.0 3.5e-141 470.1 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.18 GAM40658.1 - 3.2e-48 164.2 0.0 1.8e-43 148.7 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease HII CENP-C_C PF11699.8 GAM40659.1 - 6.5e-35 119.2 0.4 1.1e-34 118.4 0.4 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 GAM40659.1 - 2.8e-33 115.5 6.5 2.8e-33 115.5 6.5 3.6 3 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 GAM40659.1 - 4.3e-06 26.4 0.0 9.6e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Cupin domain GFO_IDH_MocA PF01408.22 GAM40660.1 - 1.6e-18 67.7 0.0 2.5e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 GAM40660.1 - 2.5e-05 24.9 0.0 4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ADK PF00406.22 GAM40661.1 - 1.9e-59 200.1 0.0 2.5e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAM40661.1 - 5.8e-23 81.8 0.0 1.1e-22 81.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 GAM40661.1 - 6.2e-18 64.5 0.0 1.6e-17 63.2 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 GAM40661.1 - 5.2e-07 30.3 0.0 8.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAM40661.1 - 1.3e-06 28.6 0.0 2.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAM40661.1 - 0.06 13.6 0.0 0.1 12.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAM40661.1 - 0.086 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MitMem_reg PF13012.6 GAM40662.1 - 4e-37 127.1 0.5 7.5e-37 126.2 0.5 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAM40662.1 - 4.6e-30 104.0 0.0 1.1e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 GAM40662.1 - 0.32 10.7 3.9 0.52 10.0 3.9 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain UCH PF00443.29 GAM40663.1 - 3.2e-10 39.9 0.0 5.5e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM40663.1 - 2.2e-08 34.1 0.0 2.2e-08 34.1 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SRR1 PF07985.12 GAM40664.1 - 1.4e-09 37.8 0.0 2.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 SRR1 L_lactis_ph-MCP PF06673.11 GAM40664.1 - 0.0087 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Lactococcus lactis bacteriophage major capsid protein Imm21 PF15589.6 GAM40664.1 - 0.082 13.0 0.0 0.54 10.3 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 21 DUF1542 PF07564.11 GAM40664.1 - 0.17 12.0 1.1 2.6 8.2 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Methyltransf_11 PF08241.12 GAM40666.1 - 1.2e-12 48.3 0.0 2.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM40666.1 - 9.9e-11 42.2 0.0 2.3e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM40666.1 - 2.7e-07 30.6 0.0 2.2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM40666.1 - 3.2e-06 27.8 0.0 8.5e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM40666.1 - 1.9e-05 24.5 0.0 3.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DnaB_bind PF10410.9 GAM40666.1 - 0.065 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase MetW PF07021.12 GAM40666.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CAP_GLY PF01302.25 GAM40667.1 - 1.3e-24 85.9 0.0 2.2e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 GAM40667.1 - 1.9e-14 53.9 0.0 3.2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 GAM40667.1 - 5.7e-05 22.8 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family MFS_1 PF07690.16 GAM40669.1 - 5.8e-21 74.8 62.0 2.4e-15 56.3 34.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CFIA_Pcf11 PF11526.8 GAM40670.1 - 6.4e-09 36.2 2.5 3.6e-08 33.8 2.5 2.3 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 GAM40670.1 - 4.9e-06 27.3 0.0 1.5e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.19 GAM40670.1 - 0.016 15.0 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 VHS domain Inhibitor_I9 PF05922.16 GAM40671.1 - 0.0039 17.8 0.0 0.0048 17.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 MctB PF11382.8 GAM40671.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB HOOK PF05622.12 GAM40672.1 - 3e-23 81.9 72.9 1.5e-20 73.0 72.9 2.6 1 1 0 1 1 1 1 HOOK protein TMPIT PF07851.13 GAM40672.1 - 0.0032 16.8 2.8 0.0032 16.8 2.8 5.3 2 1 3 5 5 5 1 TMPIT-like protein KASH_CCD PF14662.6 GAM40672.1 - 0.0084 16.0 22.4 0.0084 16.0 22.4 6.1 2 2 3 5 5 5 3 Coiled-coil region of CCDC155 or KASH Prefoldin_2 PF01920.20 GAM40672.1 - 0.021 14.8 1.5 0.021 14.8 1.5 8.9 5 2 3 8 8 8 0 Prefoldin subunit HALZ PF02183.18 GAM40672.1 - 0.031 14.5 1.6 0.031 14.5 1.6 7.1 6 1 1 7 7 7 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 GAM40672.1 - 0.67 10.0 95.0 0.057 13.5 2.3 7.6 3 2 3 6 6 6 0 TPR/MLP1/MLP2-like protein DASH_Hsk3 PF08227.11 GAM40672.1 - 3.9 7.9 12.2 19 5.7 1.4 5.3 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like Fib_alpha PF08702.10 GAM40672.1 - 7.5 6.7 63.9 0.024 14.8 6.2 6.3 3 2 1 6 6 6 0 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.12 GAM40672.1 - 9.3 6.3 18.5 2.2 8.3 1.1 5.4 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Coprogen_oxidas PF01218.18 GAM40673.1 - 1.5e-133 444.1 0.0 5.8e-133 442.2 0.0 1.7 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Apc15p PF05841.11 GAM40674.1 - 3.8e-15 56.8 0.2 3.8e-15 56.8 0.2 2.5 2 1 0 2 2 2 1 Apc15p protein Spem1 PF15670.5 GAM40674.1 - 0.067 12.8 0.2 0.067 12.8 0.2 1.7 2 0 0 2 2 2 0 Spermatid maturation protein 1 SDA1 PF05285.12 GAM40674.1 - 0.098 12.1 18.3 0.18 11.2 18.3 1.4 1 0 0 1 1 1 0 SDA1 Phage-MuB_C PF09077.11 GAM40674.1 - 0.14 12.0 1.4 0.29 11.1 1.4 1.5 1 0 0 1 1 1 0 Mu B transposition protein, C terminal CHZ PF09649.10 GAM40675.1 - 3.6e-17 61.5 2.7 3.6e-17 61.5 2.7 2.9 4 0 0 4 4 4 1 Histone chaperone domain CHZ CDC27 PF09507.10 GAM40675.1 - 8.8 5.6 16.5 9.3 5.5 16.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HSP70 PF00012.20 GAM40676.1 - 1.9e-252 838.8 9.4 4.8e-128 427.9 2.9 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GAM40676.1 - 4e-14 52.2 0.0 2.8e-09 36.3 0.0 2.9 3 0 0 3 3 3 2 MreB/Mbl protein zf-met PF12874.7 GAM40676.1 - 3.2e-06 27.3 5.3 0.0086 16.4 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type FGGY_C PF02782.16 GAM40676.1 - 0.0083 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain zf-C2H2_jaz PF12171.8 GAM40676.1 - 0.012 15.9 2.4 1.9 8.8 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Hydantoinase_A PF01968.18 GAM40676.1 - 0.056 12.7 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FtsA PF14450.6 GAM40676.1 - 0.15 12.5 3.2 21 5.6 0.0 3.6 3 0 0 3 3 3 0 Cell division protein FtsA 7TMR-DISM_7TM PF07695.11 GAM40676.1 - 0.2 11.5 2.0 0.36 10.7 2.0 1.3 1 0 0 1 1 1 0 7TM diverse intracellular signalling zf-C2H2_2 PF12756.7 GAM40676.1 - 0.32 11.3 2.8 17 5.8 0.1 2.7 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 GAM40676.1 - 0.39 10.4 6.9 2.3 8.0 0.5 3.0 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF3449 PF11931.8 GAM40676.1 - 1.7 8.4 5.7 4.5 7.0 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) zf-C2H2 PF00096.26 GAM40676.1 - 1.9 9.1 10.5 12 6.5 0.7 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type Mito_carr PF00153.27 GAM40677.1 - 2.5e-29 101.0 1.9 5.7e-14 51.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Atg8 PF02991.16 GAM40678.1 - 2.7e-51 172.1 0.2 3.2e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 GAM40678.1 - 3e-06 27.5 0.0 3.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 RNA_pol_Rpb1_1 PF04997.12 GAM40679.1 - 1.1e-79 268.1 0.0 2e-79 267.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 GAM40679.1 - 1.6e-76 257.2 0.2 2.9e-76 256.4 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAM40679.1 - 6.7e-69 231.4 0.0 1.5e-68 230.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 GAM40679.1 - 1.2e-35 122.7 0.0 3.9e-35 121.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 GAM40679.1 - 1.1e-27 96.0 0.1 3.5e-27 94.5 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Cyclin PF08613.11 GAM40680.1 - 2.8e-31 109.1 1.1 2.8e-31 109.1 1.1 2.6 2 2 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAM40680.1 - 0.00052 19.8 0.0 0.00088 19.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Beta-lactamase PF00144.24 GAM40681.1 - 4.1e-33 115.0 0.1 6.4e-33 114.4 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase CTP_transf_1 PF01148.20 GAM40682.1 - 4.7e-81 272.4 24.0 5.8e-81 272.2 24.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.8 GAM40683.1 - 5.1e-41 140.0 0.5 1.5e-40 138.4 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 GAM40683.1 - 1.5e-05 23.8 4.8 0.023 13.2 0.1 2.8 2 1 1 3 3 3 2 DNA damage checkpoint protein Fez1 PF06818.15 GAM40683.1 - 0.00033 21.2 1.8 0.00076 20.0 1.8 1.6 1 0 0 1 1 1 1 Fez1 HMMR_N PF15905.5 GAM40683.1 - 0.0012 18.3 6.9 0.0019 17.7 6.9 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal CC2-LZ PF16516.5 GAM40683.1 - 0.0095 16.3 7.7 0.031 14.6 7.7 1.9 1 1 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator V_ATPase_I PF01496.19 GAM40683.1 - 0.036 12.0 4.4 0.055 11.4 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 GAM40683.1 - 0.084 13.5 4.8 0.38 11.4 3.0 2.6 1 1 1 2 2 2 0 Initiation control protein YabA BPA_C PF18040.1 GAM40683.1 - 0.15 12.0 0.1 0.44 10.5 0.1 1.7 1 0 0 1 1 1 0 beta porphyranase A C-terminal Spc24 PF08286.11 GAM40683.1 - 0.66 10.2 4.1 2.8 8.2 4.1 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 GAM40683.1 - 1.7 7.9 10.4 3.2 7.0 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 GAM40683.1 - 2 8.8 9.0 1.7 9.1 3.3 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF4140 PF13600.6 GAM40683.1 - 2.6 8.5 7.8 10 6.6 0.7 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) S4 PF01479.25 GAM40684.1 - 3.1e-14 52.4 0.0 6.5e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain SPG4 PF17325.2 GAM40684.1 - 0.029 15.4 1.0 0.029 15.4 1.0 2.7 2 1 0 2 2 2 0 Stationary phase protein 4 S4_2 PF13275.6 GAM40684.1 - 0.088 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 S4 domain SabA_adhesion PF18304.1 GAM40684.1 - 0.39 9.9 3.7 0.34 10.1 2.3 1.6 1 1 0 1 1 1 0 SabA N-terminal extracellular adhesion domain XRN_M PF17846.1 GAM40684.1 - 0.43 9.5 6.9 1.7 7.5 3.2 2.1 1 1 1 2 2 2 0 Xrn1 helical domain SOBP PF15279.6 GAM40684.1 - 6.1 7.4 9.6 0.96 10.0 6.0 1.5 2 0 0 2 2 2 0 Sine oculis-binding protein DUF2508 PF10704.9 GAM40685.1 - 0.043 14.0 2.0 0.13 12.5 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) SPX PF03105.19 GAM40685.1 - 0.2 11.5 21.1 0.049 13.5 0.7 2.2 2 0 0 2 2 2 0 SPX domain E1_dh PF00676.20 GAM40686.1 - 6.8e-113 376.6 0.1 8.4e-113 376.3 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 GAM40686.1 - 0.00037 19.8 0.0 0.00072 18.9 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase PH_10 PF15411.6 GAM40687.1 - 1.3e-26 93.2 0.1 3.8e-26 91.8 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 GAM40687.1 - 7.1e-14 52.4 0.0 1.4e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAM40687.1 - 1.6e-10 41.1 0.2 7.2e-09 35.8 0.0 3.0 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 GAM40687.1 - 0.00088 19.6 5.4 0.002 18.4 5.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GAM40687.1 - 0.0033 17.4 6.0 0.0065 16.4 6.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAM40687.1 - 0.0048 17.2 2.9 0.012 15.9 2.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 GAM40687.1 - 0.011 15.3 3.0 0.011 15.3 3.0 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 GAM40687.1 - 0.013 15.3 6.2 0.029 14.3 6.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM40687.1 - 0.015 15.1 4.9 0.039 13.8 4.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 GAM40687.1 - 0.043 14.1 4.8 0.1 12.9 4.8 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 GAM40687.1 - 0.075 12.9 2.2 0.18 11.7 2.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 GAM40687.1 - 0.28 11.3 0.7 0.52 10.5 0.7 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3H2C3 PF17122.5 GAM40687.1 - 0.58 10.2 5.5 1.4 9.0 5.5 1.7 1 1 0 1 1 1 0 Zinc-finger zf-RING_11 PF17123.5 GAM40687.1 - 1.4 8.7 3.4 3.3 7.5 3.4 1.7 1 0 0 1 1 1 0 RING-like zinc finger Cpn60_TCP1 PF00118.24 GAM40688.1 - 9.1e-150 499.5 7.0 1.1e-149 499.3 7.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.20 GAM40688.1 - 0.011 15.2 0.0 0.033 13.7 0.0 1.7 2 0 0 2 2 2 0 EAL domain PPP4R2 PF09184.11 GAM40688.1 - 0.022 14.4 3.3 0.028 14.0 2.4 1.7 2 0 0 2 2 2 0 PPP4R2 PrpR_N PF06506.11 GAM40688.1 - 0.034 13.7 0.2 0.14 11.8 0.1 2.1 2 0 0 2 2 2 0 Propionate catabolism activator RPN2_C PF18004.1 GAM40688.1 - 0.074 13.0 1.8 0.17 11.8 1.8 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain WRNPLPNID PF15017.6 GAM40688.1 - 0.11 13.4 9.5 0.31 12.0 9.5 1.8 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box TFB6 PF17110.5 GAM40688.1 - 0.11 12.2 1.6 0.34 10.7 1.6 1.8 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RXT2_N PF08595.11 GAM40688.1 - 0.11 12.5 3.5 0.29 11.2 3.5 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal RNA_pol_3_Rpc31 PF11705.8 GAM40688.1 - 0.15 12.3 8.7 0.3 11.3 8.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sigma70_ner PF04546.13 GAM40688.1 - 0.48 10.3 7.8 0.11 12.4 3.9 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 GAM40688.1 - 1.1 7.3 12.8 2 6.4 12.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pns11_12 PF17464.2 GAM40688.1 - 1.3 8.7 4.0 2.2 7.9 4.0 1.3 1 0 0 1 1 1 0 Non-structural protein 11 and 12 CobT PF06213.12 GAM40688.1 - 1.8 7.9 9.8 4.3 6.6 9.8 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 GAM40688.1 - 1.9 7.8 9.2 3.1 7.1 9.2 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 GAM40688.1 - 2.2 8.7 12.6 5.1 7.5 12.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 GAM40688.1 - 2.4 7.8 6.3 5 6.8 6.3 1.5 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 GAM40688.1 - 4.7 5.3 11.2 0.58 8.3 6.6 1.6 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.12 GAM40688.1 - 8.7 5.7 12.7 1.3 8.4 8.9 1.4 2 0 0 2 2 2 0 SDA1 Ribosomal_L12 PF00542.19 GAM40689.1 - 5.4e-20 71.5 6.9 1.7e-18 66.7 5.1 2.3 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 GAM40689.1 - 4.4e-11 42.3 11.3 4.4e-11 42.3 11.3 3.7 4 1 0 4 4 4 1 Ribosomal protein L7/L12 dimerisation domain Glyoxalase PF00903.25 GAM40690.1 - 3.1e-10 40.3 0.0 8.1e-10 39.0 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAM40690.1 - 7.4e-06 26.2 0.0 1.1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PrpR_N PF06506.11 GAM40690.1 - 0.036 13.6 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Propionate catabolism activator Glyoxalase_2 PF12681.7 GAM40690.1 - 0.072 13.0 0.0 4.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Glyoxalase-like domain Sel1 PF08238.12 GAM40691.1 - 0.0078 16.9 6.9 1.3 9.8 0.2 3.4 3 0 0 3 3 3 2 Sel1 repeat DUF3104 PF11302.8 GAM40692.1 - 0.12 12.2 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) SYF2 PF08231.12 GAM40693.1 - 4.3e-58 196.2 15.4 4.3e-58 196.2 15.4 2.0 2 0 0 2 2 2 1 SYF2 splicing factor TMEM214 PF10151.9 GAM40693.1 - 8.9 4.6 7.4 19 3.6 7.4 1.4 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator NAD_binding_10 PF13460.6 GAM40694.1 - 5.9e-07 29.5 0.0 4.8e-06 26.6 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM40694.1 - 2.1e-05 24.1 0.0 4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 GAM40694.1 - 0.004 16.6 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 GAM40694.1 - 0.0063 15.5 0.0 0.016 14.2 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAM40694.1 - 0.0076 15.5 0.1 0.13 11.4 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 GAM40694.1 - 0.008 15.3 0.0 0.062 12.4 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 GAM40694.1 - 0.0087 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 KR domain YEATS PF03366.16 GAM40695.1 - 3.1e-36 123.2 1.7 4.4e-36 122.7 1.7 1.2 1 0 0 1 1 1 1 YEATS family Chs7 PF12271.8 GAM40697.1 - 3.4e-109 364.6 6.8 4.1e-109 364.4 6.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DLH PF01738.18 GAM40698.1 - 5.9e-29 101.2 0.0 7.2e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 GAM40698.1 - 0.012 15.6 0.0 0.22 11.4 0.0 2.0 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 GAM40698.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LIDHydrolase PF10230.9 GAM40698.1 - 0.025 14.1 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Melibiase_2 PF16499.5 GAM40699.1 - 1.6e-47 162.1 0.3 3.3e-47 161.0 0.3 1.6 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 GAM40699.1 - 2.8e-12 46.5 0.2 8.6e-12 45.0 0.2 1.9 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain DUF4251 PF14059.6 GAM40699.1 - 1.3 9.0 4.5 4.1 7.4 0.1 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4251) Glyco_hydro_28 PF00295.17 GAM40700.1 - 2.5e-25 89.2 4.9 3.6e-25 88.7 4.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 GAM40700.1 - 0.00019 21.3 11.1 0.0005 20.0 9.1 2.7 2 1 0 2 2 2 1 Pectate lyase superfamily protein zf-C3HC4 PF00097.25 GAM40701.1 - 1.8e-07 30.9 6.2 3.4e-07 30.0 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM40701.1 - 1.9e-07 30.8 6.5 1.7e-06 27.7 3.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM40701.1 - 3.1e-06 27.4 7.0 4.2e-05 23.8 7.5 2.2 1 1 1 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.6 GAM40701.1 - 4.9e-06 26.5 6.1 5.3e-06 26.4 1.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAM40701.1 - 2e-05 24.6 4.5 0.00014 22.0 5.0 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 GAM40701.1 - 6.7e-05 22.7 5.0 0.00015 21.6 5.0 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM40701.1 - 8.8e-05 22.4 4.8 0.00027 20.8 4.8 1.9 1 1 1 2 2 2 1 zinc-RING finger domain TerY_C PF15616.6 GAM40701.1 - 0.13 12.3 0.4 0.29 11.3 0.4 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain Prok-RING_4 PF14447.6 GAM40701.1 - 0.28 11.1 9.0 7.2 6.6 9.4 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.20 GAM40701.1 - 0.33 10.7 9.6 1.7 8.5 9.0 2.2 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_11 PF17123.5 GAM40701.1 - 2.3 8.0 8.1 27 4.6 6.0 2.7 2 1 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 GAM40701.1 - 6 7.2 6.4 22 5.4 6.4 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain UCH PF00443.29 GAM40702.1 - 1.7e-44 152.3 0.0 2.6e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM40702.1 - 2e-10 40.8 0.0 1.1e-08 35.0 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cauli_VI PF01693.16 GAM40703.1 - 4.2e-39 132.6 7.8 3.2e-19 68.9 1.7 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 GAM40703.1 - 3e-37 128.0 0.0 5.4e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 GAM40703.1 - 0.0016 18.3 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like Na_H_Exchanger PF00999.21 GAM40704.1 - 9e-47 159.7 23.5 1.1e-46 159.3 23.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3464 PF11947.8 GAM40704.1 - 2.3 7.9 4.8 4.9 6.9 0.2 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 p450 PF00067.22 GAM40705.1 - 1.2e-07 30.9 0.1 0.0017 17.2 0.0 2.9 2 1 0 2 2 2 2 Cytochrome P450 VESA1_N PF12785.7 GAM40705.1 - 0.045 12.7 0.0 0.065 12.2 0.0 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 DUF3948 PF13134.6 GAM40705.1 - 0.097 12.4 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) TPR_12 PF13424.6 GAM40706.1 - 3.3e-20 72.2 0.7 9.4e-07 29.0 0.0 6.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAM40706.1 - 1.2e-12 47.2 3.4 0.00022 21.0 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM40706.1 - 2e-10 40.0 1.1 0.2 11.9 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAM40706.1 - 2.5e-10 39.7 0.0 0.0061 16.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 GAM40706.1 - 6.2e-08 32.1 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain PNP_UDP_1 PF01048.20 GAM40706.1 - 1.1e-07 31.3 0.0 2.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_7 PF13176.6 GAM40706.1 - 5.2e-06 26.1 0.1 1.7 8.8 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM40706.1 - 3.9e-05 23.5 0.3 4.5 7.7 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 GAM40706.1 - 0.00072 20.0 0.3 0.0029 18.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain TPR_16 PF13432.6 GAM40706.1 - 0.0024 18.5 0.3 24 5.7 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM40706.1 - 0.0095 16.4 0.3 0.29 11.7 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.6 GAM40706.1 - 0.012 15.9 0.0 0.04 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAM40706.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 GAM40706.1 - 0.058 13.3 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TPR_4 PF07721.14 GAM40706.1 - 0.062 14.0 0.0 0.42 11.4 0.0 2.5 2 0 0 2 2 1 0 Tetratricopeptide repeat Coatomer_E PF04733.14 GAM40706.1 - 0.063 12.7 0.1 1.7 8.0 0.1 2.6 3 0 0 3 3 3 0 Coatomer epsilon subunit TPR_14 PF13428.6 GAM40706.1 - 0.078 13.8 6.6 4.8 8.3 0.1 5.8 6 1 1 7 7 6 0 Tetratricopeptide repeat DUF3445 PF11927.8 GAM40706.1 - 0.14 11.8 0.2 0.72 9.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3445) PTPLA PF04387.14 GAM40707.1 - 2.9e-59 199.5 6.5 4.1e-59 199.0 6.5 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Adaptin_binding PF10199.9 GAM40708.1 - 1.7e-18 67.4 0.8 5.2e-17 62.6 3.8 1.9 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 DUF4611 PF15387.6 GAM40708.1 - 8.8 6.6 11.0 3.8 7.8 1.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) LSM PF01423.22 GAM40709.1 - 1.7e-15 56.4 0.2 2.3e-15 56.0 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAM40709.1 - 0.091 12.9 0.1 0.16 12.1 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain PGP_phosphatase PF09419.10 GAM40710.1 - 1.6e-53 180.8 0.0 2e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 GAM40710.1 - 1.3e-05 25.1 0.1 2.5e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAM40710.1 - 0.0046 17.3 0.1 1.8 8.8 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 GAM40711.1 - 6.9e-20 70.7 4.5 1.6e-19 69.5 4.5 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAM40711.1 - 0.00077 19.3 0.6 0.0017 18.2 0.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain Beta-lactamase PF00144.24 GAM40712.1 - 2.9e-37 128.7 0.0 3.4e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_15 PF00723.21 GAM40713.1 - 5.7e-104 348.4 1.9 6.9e-104 348.1 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 GAM40713.1 - 3e-36 123.2 1.2 7.6e-36 121.9 1.2 1.7 1 0 0 1 1 1 1 Starch binding domain Abhydrolase_1 PF00561.20 GAM40714.1 - 9.9e-11 41.8 0.4 2.4e-09 37.3 0.2 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM40714.1 - 1.1e-07 32.7 4.5 1.6e-07 32.2 4.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM40714.1 - 5.9e-06 25.7 0.0 1.7e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 GAM40714.1 - 0.071 13.5 0.1 0.25 11.7 0.1 2.0 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DUF1057 PF06342.12 GAM40714.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PhyH PF05721.13 GAM40715.1 - 3.1e-12 47.2 0.0 4.5e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 GAM40715.1 - 2.2e-08 33.3 0.1 0.019 13.8 0.1 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) MFS_1 PF07690.16 GAM40716.1 - 1.8e-31 109.3 34.4 1.8e-31 109.3 34.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM40716.1 - 0.00029 20.2 9.3 0.00029 20.2 9.3 2.2 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2619 PF10942.8 GAM40716.1 - 0.082 13.0 2.3 2.4 8.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2619) SH3_3 PF08239.11 GAM40717.1 - 0.0012 19.1 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 GAM40717.1 - 0.023 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain PhoLip_ATPase_C PF16212.5 GAM40720.1 - 2e-74 250.5 24.1 2e-74 250.5 24.1 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAM40720.1 - 1e-24 86.0 0.9 1.8e-23 82.0 0.1 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GAM40720.1 - 3.1e-12 46.4 0.0 2.4e-11 43.6 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM40720.1 - 4.5e-12 46.7 1.0 5.1e-07 30.2 0.6 3.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAM40720.1 - 8.3e-12 45.0 0.1 8.3e-12 45.0 0.1 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAM40720.1 - 0.0063 16.3 0.2 0.02 14.6 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sec62 PF03839.16 GAM40720.1 - 4.3 6.8 5.8 15 5.0 5.8 1.9 1 0 0 1 1 1 0 Translocation protein Sec62 SRP_TPR_like PF17004.5 GAM40723.1 - 1.7e-21 76.4 2.2 4.1e-21 75.2 1.4 2.1 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 GAM40723.1 - 1.8e-17 63.5 9.4 1.8e-17 63.5 9.4 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 GAM40723.1 - 1.3e-06 28.8 11.7 0.06 13.9 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM40723.1 - 0.0011 19.1 5.3 4.6 7.5 0.0 4.6 4 2 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 GAM40723.1 - 0.0062 16.6 13.2 15 6.0 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAM40723.1 - 0.057 14.1 3.3 26 5.8 0.3 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 GAM40723.1 - 0.064 13.5 0.6 11 6.5 0.0 3.6 3 0 0 3 3 3 0 PPR repeat TMEM82 PF15816.5 GAM40723.1 - 0.15 11.0 0.1 0.23 10.4 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 82 TPR_7 PF13176.6 GAM40723.1 - 1 9.6 8.5 8.5 6.7 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAM40723.1 - 3.9 7.9 8.0 4.6 7.6 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 GAM40723.1 - 6 7.3 15.9 0.79 10.2 0.5 4.7 5 0 0 5 5 5 0 Bacterial transcriptional activator domain Asp PF00026.23 GAM40724.1 - 1.2e-53 182.6 6.5 1.4e-53 182.3 6.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAM40724.1 - 1.2e-05 25.1 0.1 0.0011 18.8 0.1 2.9 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 GAM40724.1 - 8.6e-05 23.1 1.3 0.9 10.2 0.0 3.6 4 0 0 4 4 4 2 Aspartyl protease gag-asp_proteas PF13975.6 GAM40724.1 - 0.0017 18.9 0.1 0.5 11.0 0.0 2.8 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 GAM40724.1 - 0.0026 18.0 2.7 0.033 14.4 2.7 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Fringe PF02434.16 GAM40725.1 - 9.1e-10 38.4 0.2 2.3e-09 37.1 0.2 1.7 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.12 GAM40725.1 - 1.1e-08 34.8 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fungal_trans PF04082.18 GAM40727.1 - 6.2e-13 48.4 0.9 6.2e-13 48.4 0.9 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3961 PF13106.6 GAM40727.1 - 0.15 11.7 0.0 20 4.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) Glyco_hydro_15 PF00723.21 GAM40728.1 - 3.8e-101 339.1 0.5 4.7e-101 338.8 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 GAM40728.1 - 1.6e-26 92.0 0.4 5.4e-26 90.3 0.1 2.1 2 0 0 2 2 2 1 Starch binding domain Alpha-amylase PF00128.24 GAM40729.1 - 2.1e-51 175.5 0.1 5.8e-51 174.0 0.1 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 GAM40729.1 - 1.8e-27 95.4 0.1 3.9e-27 94.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF871 PF05913.11 GAM40729.1 - 0.039 13.2 0.0 0.27 10.4 0.0 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF871) FliD_N PF02465.18 GAM40729.1 - 0.34 11.6 3.0 0.23 12.2 0.8 1.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Homeobox_KN PF05920.11 GAM40730.1 - 5.7e-21 74.1 0.3 5.7e-21 74.1 0.3 1.8 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 GAM40730.1 - 9e-07 28.7 0.1 2.2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Homeodomain PEP_mutase PF13714.6 GAM40731.1 - 9.9e-40 136.5 0.0 1.2e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 GAM40731.1 - 1.1e-21 76.9 0.0 1.5e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Isocitrate lyase family FAD_binding_1 PF00667.20 GAM40733.1 - 6.4e-46 156.7 0.0 9.1e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GAM40733.1 - 4.7e-10 40.1 0.0 2e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Glyco_hydro_47 PF01532.20 GAM40734.1 - 3.8e-186 619.5 0.0 4.4e-186 619.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 GAM40734.1 - 0.035 12.6 0.0 0.79 8.1 0.0 2.1 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Med20 PF08612.11 GAM40735.1 - 5.7e-67 225.4 0.0 6.9e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex BES1_N PF05687.13 GAM40735.1 - 0.31 11.4 5.1 0.63 10.4 5.1 1.5 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal EF-hand_1 PF00036.32 GAM40736.1 - 1.3e-41 137.0 11.6 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAM40736.1 - 3.6e-36 123.4 5.3 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GAM40736.1 - 1.9e-34 117.3 11.5 2.4e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 GAM40736.1 - 3.8e-30 101.2 8.5 7.1e-09 34.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAM40736.1 - 6.8e-26 88.6 9.8 4.7e-06 25.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GAM40736.1 - 1.4e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GAM40736.1 - 6.8e-10 38.8 1.6 0.00078 19.4 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAM40736.1 - 5.9e-09 36.2 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 GAM40736.1 - 1e-06 28.6 0.1 0.008 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 GAM40736.1 - 6.4e-06 26.2 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 GAM40736.1 - 9.4e-05 23.2 0.2 0.0025 18.6 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 GAM40736.1 - 0.00013 21.9 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 GAM40736.1 - 0.00059 19.8 1.6 0.52 10.2 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 GAM40736.1 - 0.00062 20.1 0.7 0.66 10.3 0.1 2.6 2 1 1 3 3 3 2 RNA polymerase Rpb4 Dockerin_1 PF00404.18 GAM40736.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 GAM40736.1 - 0.0057 15.3 0.0 0.0058 15.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 GAM40736.1 - 0.0084 16.0 0.7 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 GAM40736.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 GAM40736.1 - 0.023 14.9 0.0 0.18 12.0 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein RuvA_C PF07499.13 GAM40736.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain dCache_2 PF08269.11 GAM40736.1 - 0.061 12.5 0.1 1 8.5 0.1 2.1 1 1 1 2 2 2 0 Cache domain MotA_activ PF09114.10 GAM40736.1 - 0.061 13.5 0.3 0.91 9.7 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF4497 PF14924.6 GAM40736.1 - 0.092 13.2 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RloB PF13707.6 GAM40736.1 - 0.11 12.7 1.3 0.72 10.0 0.2 2.1 1 1 1 2 2 2 0 RloB-like protein DUF5132 PF17195.4 GAM40736.1 - 0.16 12.1 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) SNARE PF05739.19 GAM40737.1 - 6.9e-16 58.0 2.5 1.6e-15 56.8 2.5 1.6 1 0 0 1 1 1 1 SNARE domain DUF2615 PF11027.8 GAM40737.1 - 0.052 13.7 0.9 0.083 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) KxDL PF10241.9 GAM40737.1 - 0.071 13.4 0.1 0.071 13.4 0.1 3.2 3 1 1 4 4 4 0 Uncharacterized conserved protein DUF948 PF06103.11 GAM40737.1 - 0.21 11.9 3.7 32 4.9 0.1 3.9 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Syntaxin PF00804.25 GAM40737.1 - 0.29 10.8 14.3 0.83 9.3 14.3 1.8 1 1 0 1 1 1 0 Syntaxin MCPsignal PF00015.21 GAM40737.1 - 3.2 7.5 9.9 0.39 10.5 2.0 2.6 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BBP1_C PF15272.6 GAM40737.1 - 4.4 7.1 11.3 2.6 7.8 2.6 2.5 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal DUF4407 PF14362.6 GAM40737.1 - 9.1 5.5 13.1 0.082 12.3 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CTD_bind PF04818.13 GAM40738.1 - 5.4e-19 68.8 0.1 1.4e-18 67.4 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Dynamitin PF04912.14 GAM40738.1 - 0.023 14.1 1.0 0.041 13.2 1.0 1.3 1 0 0 1 1 1 0 Dynamitin CTK3 PF12243.8 GAM40738.1 - 0.085 12.9 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 DUF3277 PF11681.8 GAM40738.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Clathrin_lg_ch PF01086.17 GAM40739.1 - 3.9e-76 256.1 3.2 4.4e-76 256.0 3.2 1.0 1 0 0 1 1 1 1 Clathrin light chain CDC37_N PF03234.14 GAM40740.1 - 3.9e-50 170.1 2.7 3.9e-50 170.1 2.7 3.0 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 GAM40740.1 - 4.1e-40 136.4 0.1 2.1e-39 134.1 0.0 2.1 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 GAM40740.1 - 2.2e-35 120.8 1.1 2.2e-35 120.8 1.1 2.6 3 0 0 3 3 3 1 Cdc37 C terminal domain Cytochrom_B562 PF07361.11 GAM40740.1 - 0.052 14.2 0.6 4.6 8.0 0.1 3.2 2 2 0 2 2 2 0 Cytochrome b562 DUF3573 PF12097.8 GAM40740.1 - 0.33 9.7 0.8 0.62 8.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ABC_membrane PF00664.23 GAM40741.1 - 3.8e-49 167.8 8.0 5e-49 167.4 8.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAM40741.1 - 9.4e-36 123.4 0.0 4.1e-35 121.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 GAM40741.1 - 1.5e-05 24.6 0.0 0.0015 18.0 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 GAM40741.1 - 0.0048 17.3 0.0 0.071 13.5 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM40741.1 - 0.0052 17.2 0.0 0.018 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM40741.1 - 0.0072 16.6 0.1 0.052 13.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GAM40741.1 - 0.0085 15.8 0.1 0.023 14.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 GAM40741.1 - 0.035 13.8 0.1 0.1 12.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAM40741.1 - 0.044 13.5 0.1 0.42 10.3 0.0 2.3 2 1 0 2 2 2 0 IstB-like ATP binding protein DUF5577 PF17740.1 GAM40741.1 - 0.07 12.8 2.1 0.13 11.9 2.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5577) AAA_5 PF07728.14 GAM40741.1 - 0.12 12.4 0.0 0.62 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 GAM40741.1 - 0.18 12.1 0.6 2.3 8.5 0.6 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit GDWWSH PF15667.5 GAM40741.1 - 0.19 11.1 1.7 0.29 10.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function with motif GDWWSH AAA_23 PF13476.6 GAM40741.1 - 0.3 11.6 2.1 0.71 10.3 0.0 2.5 3 0 0 3 3 2 0 AAA domain Nucleoside_tran PF01733.18 GAM40742.1 - 2.3e-47 161.9 1.6 2.3e-47 161.9 1.6 1.8 1 1 1 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 GAM40742.1 - 0.13 11.1 38.2 0.44 9.4 4.0 3.0 2 1 1 3 3 3 0 Major Facilitator Superfamily APH PF01636.23 GAM40743.1 - 3.2e-14 53.4 0.1 8.3e-12 45.5 0.0 2.5 2 1 0 2 2 2 2 Phosphotransferase enzyme family DUF5439 PF17507.2 GAM40743.1 - 0.16 12.2 0.0 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5439) Haspin_kinase PF12330.8 GAM40744.1 - 2.2e-40 138.7 0.0 3.9e-40 137.9 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain COX7a PF02238.15 GAM40746.1 - 8.3e-21 74.1 2.6 1.1e-20 73.8 2.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII LAB_N PF07578.11 GAM40746.1 - 0.046 13.8 0.3 0.06 13.4 0.3 1.3 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain Nitroreductase PF00881.24 GAM40748.1 - 7.4e-12 45.6 0.0 1.2e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family Fungal_trans PF04082.18 GAM40748.1 - 3e-05 23.2 0.1 6.1e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.19 GAM40749.1 - 3.9e-06 26.1 0.0 5.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V IDO PF01231.18 GAM40750.1 - 7.4e-151 502.8 0.0 8.5e-151 502.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF4246 PF14033.6 GAM40751.1 - 8.4e-175 582.2 0.3 1e-174 582.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 GAM40751.1 - 0.038 14.4 0.0 0.1 13.1 0.0 1.7 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Ins_P5_2-kin PF06090.12 GAM40752.1 - 7.3e-54 183.4 0.0 4.1e-53 181.0 0.0 1.8 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Seadorna_VP6 PF07407.11 GAM40752.1 - 0.0086 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP6 protein DUF1682 PF07946.14 GAM40753.1 - 1.2e-115 386.2 0.1 2e-115 385.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ge1_WD40 PF16529.5 GAM40755.1 - 0.0019 17.2 0.0 0.004 16.2 0.0 1.5 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CLZ PF16526.5 GAM40755.1 - 0.18 12.2 3.8 0.36 11.2 0.4 3.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Atg14 PF10186.9 GAM40755.1 - 1.2 8.2 4.6 0.88 8.6 2.4 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 GAM40755.1 - 4.5 7.3 8.3 0.49 10.5 2.9 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GATase_2 PF00310.21 GAM40756.1 - 6.5e-181 601.6 0.0 8.8e-181 601.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 GAM40756.1 - 7.6e-157 522.2 0.2 1.4e-156 521.3 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 GAM40756.1 - 1.1e-115 385.9 0.0 5.4e-113 377.1 0.0 2.2 2 0 0 2 2 2 2 Glutamate synthase central domain GXGXG PF01493.19 GAM40756.1 - 4e-85 284.2 4.2 6.4e-85 283.6 4.2 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 GAM40756.1 - 6.2e-28 97.9 0.2 2e-27 96.2 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 GAM40756.1 - 2.5e-21 75.5 0.1 5e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 GAM40756.1 - 1.1e-08 35.2 0.0 3.6e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM40756.1 - 2.3e-08 34.0 2.0 0.0016 18.1 0.4 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM40756.1 - 2.9e-08 34.1 0.2 3.5e-05 24.3 0.1 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM40756.1 - 5.6e-08 32.4 1.8 0.016 14.5 0.0 4.0 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAM40756.1 - 4e-07 29.7 0.2 7.8e-07 28.7 0.2 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 GAM40756.1 - 1.1e-05 24.9 0.3 2.6e-05 23.7 0.3 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM40756.1 - 3.4e-05 23.1 0.2 0.00021 20.5 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAM40756.1 - 4.6e-05 22.3 0.3 4.6e-05 22.3 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 GAM40756.1 - 0.0002 20.8 0.0 0.00058 19.2 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 GAM40756.1 - 0.00025 21.4 0.1 1 9.8 0.1 2.8 2 0 0 2 2 2 2 Putative NAD(P)-binding FMO-like PF00743.19 GAM40756.1 - 0.00083 17.9 0.1 0.3 9.5 0.0 2.9 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like AlaDh_PNT_C PF01262.21 GAM40756.1 - 0.0011 18.4 0.1 0.21 10.9 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GAM40756.1 - 0.0044 16.3 0.3 0.027 13.7 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 GAM40756.1 - 0.0051 15.9 0.4 0.34 9.9 0.2 2.5 2 0 0 2 2 2 1 Lycopene cyclase protein PG_isomerase_N PF18353.1 GAM40756.1 - 0.018 15.4 0.0 0.046 14.1 0.0 1.7 1 0 0 1 1 1 0 Phosphoglucose isomerase N-terminal domain GIDA PF01134.22 GAM40756.1 - 0.076 12.1 3.2 0.045 12.8 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 GAM40756.1 - 0.11 11.8 0.1 0.53 9.6 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GAM40756.1 - 0.17 12.5 0.1 2.2 8.9 0.1 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FMN_dh PF01070.18 GAM40756.1 - 0.39 9.7 2.2 1.2 8.1 1.8 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DUF3128 PF11326.8 GAM40757.1 - 1.3e-25 89.5 3.5 1.3e-25 89.5 3.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) DnaJ PF00226.31 GAM40757.1 - 0.14 12.3 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 DnaJ domain tRNA-synt_1c PF00749.21 GAM40758.1 - 5e-99 331.2 0.0 6.1e-99 330.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAM40758.1 - 7e-29 100.9 0.0 1.7e-28 99.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Raptor_N PF14538.6 GAM40758.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain RNA12 PF10443.9 GAM40759.1 - 3.1e-163 543.6 0.0 4.5e-163 543.1 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein MFS_1 PF07690.16 GAM40759.1 - 1.1e-34 119.9 38.9 1.1e-34 119.9 38.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily ATPase_2 PF01637.18 GAM40759.1 - 1.7e-05 24.9 0.1 8.2e-05 22.6 0.0 2.2 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 GAM40759.1 - 7.3e-05 22.5 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ScsC_N PF18312.1 GAM40759.1 - 0.016 15.0 2.3 9.2 6.2 0.0 3.7 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain ATP-synt_ab PF00006.25 GAM40759.1 - 0.043 13.5 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2487 PF10673.9 GAM40759.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) OATP PF03137.20 GAM40759.1 - 0.076 11.3 3.3 3.4 5.8 4.8 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family AAA_16 PF13191.6 GAM40759.1 - 0.096 13.1 0.0 0.33 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain MFS_1 PF07690.16 GAM40760.1 - 3.7e-14 52.4 14.9 2.3e-09 36.7 10.0 3.5 1 1 2 3 3 3 3 Major Facilitator Superfamily MscL PF01741.18 GAM40761.1 - 1.6e-19 70.4 0.0 2e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL FMN_dh PF01070.18 GAM40762.1 - 4.1e-105 351.6 0.0 5.3e-105 351.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase adh_short PF00106.25 GAM40762.1 - 3.5e-42 144.1 0.0 7.1e-41 139.8 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40762.1 - 3.3e-27 95.5 0.0 1.3e-26 93.6 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Cyt-b5 PF00173.28 GAM40762.1 - 4.2e-20 71.7 0.0 1.4e-19 70.0 0.0 2.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain KR PF08659.10 GAM40762.1 - 8.4e-11 42.1 0.0 1.8e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Glu_synthase PF01645.17 GAM40762.1 - 1.2e-06 27.9 0.1 2.8e-06 26.7 0.1 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase NAD_binding_10 PF13460.6 GAM40762.1 - 9.3e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding IMPDH PF00478.25 GAM40762.1 - 2.8e-05 23.3 0.1 0.00026 20.1 0.0 2.3 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Epimerase PF01370.21 GAM40762.1 - 0.0002 20.9 0.0 0.00045 19.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAM40762.1 - 0.00032 20.3 0.0 0.00061 19.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 GAM40762.1 - 0.0081 15.6 0.0 0.03 13.7 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NMO PF03060.15 GAM40762.1 - 0.023 14.1 0.2 0.053 12.9 0.2 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase DUF1776 PF08643.10 GAM40762.1 - 0.053 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) His_biosynth PF00977.21 GAM40762.1 - 0.11 12.0 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Aminotran_1_2 PF00155.21 GAM40763.1 - 5.2e-66 223.3 0.0 6.5e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAM40763.1 - 0.0024 17.2 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 GAM40763.1 - 0.062 12.2 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Tmemb_18A PF09771.9 GAM40763.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 ACAS_N PF16177.5 GAM40764.1 - 3.6e-06 26.8 1.5 5.5e-06 26.2 1.5 1.3 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus NDUF_B12 PF08122.12 GAM40764.1 - 0.055 13.5 1.2 0.13 12.3 0.3 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Peptidase_M16_C PF05193.21 GAM40765.1 - 1.1e-51 175.5 0.0 2.3e-51 174.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAM40765.1 - 1e-41 142.4 0.0 2.3e-40 138.0 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) AMP-binding PF00501.28 GAM40765.1 - 4.1e-38 131.1 0.0 7.3e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Tom22 PF04281.13 GAM40766.1 - 3.1e-30 104.8 3.1 5.5e-30 104.0 0.3 1.9 1 1 1 2 2 2 1 Mitochondrial import receptor subunit Tom22 PP1c_bdg PF10488.9 GAM40766.1 - 0.047 13.2 0.1 0.054 13.0 0.1 1.1 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region MBR1 PF17058.5 GAM40766.1 - 0.31 11.3 3.7 2.9 8.1 2.0 2.0 1 1 1 2 2 2 0 Mitochondrial biogenesis regulation protein 1 DUF4211 PF13926.6 GAM40767.1 - 3.3e-40 137.5 0.2 1.3e-39 135.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) Glyco_hydro_70 PF02324.16 GAM40767.1 - 0.062 11.5 0.1 0.094 10.9 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 zf-C2H2_assoc2 PF16624.5 GAM40767.1 - 0.14 13.2 2.3 1.3 10.1 2.3 2.7 1 0 0 1 1 1 0 Unstructured region upstream of a zinc-finger RBR PF17208.3 GAM40767.1 - 1.5 9.6 9.9 0.54 11.0 4.4 3.0 3 0 0 3 3 3 0 RNA binding Region Auxin_canalis PF05703.11 GAM40767.1 - 1.8 8.4 6.3 0.49 10.3 2.8 1.8 1 1 1 2 2 2 0 Auxin canalisation F-box-like PF12937.7 GAM40768.1 - 7.9e-06 25.7 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like RNA_pol_3_Rpc31 PF11705.8 GAM40769.1 - 0.00022 21.6 5.3 0.00022 21.6 5.3 2.2 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 GAM40769.1 - 0.061 12.7 23.0 0.21 11.0 9.7 2.1 2 0 0 2 2 2 0 SDA1 DUF913 PF06025.12 GAM40769.1 - 0.19 10.7 1.9 1.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.16 GAM40769.1 - 0.3 10.3 14.5 1.4 8.0 1.4 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Na_trans_assoc PF06512.13 GAM40769.1 - 0.35 11.1 9.7 0.42 10.9 1.7 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated DUF4065 PF13274.6 GAM40769.1 - 0.55 11.1 9.7 1.6 9.6 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) MEA1 PF06910.11 GAM40769.1 - 0.64 10.6 12.8 1.1 9.9 0.3 2.3 2 0 0 2 2 2 0 Male enhanced antigen 1 (MEA1) Mpp10 PF04006.12 GAM40769.1 - 0.74 8.2 23.4 1.1 7.6 11.0 2.1 2 0 0 2 2 2 0 Mpp10 protein TFIIA PF03153.13 GAM40769.1 - 1.3 8.9 16.9 2.9 7.8 1.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 GAM40769.1 - 2.8 7.2 21.3 1 8.6 1.9 2.1 2 0 0 2 2 2 0 BUD22 DARPP-32 PF05395.12 GAM40769.1 - 4 7.7 17.7 4.4 7.5 3.3 2.3 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 MTBP_N PF14918.6 GAM40769.1 - 4.3 6.7 9.5 0.025 14.1 1.0 1.6 2 0 0 2 2 1 0 MDM2-binding Sigma70_ner PF04546.13 GAM40769.1 - 4.9 7.0 27.1 1.1 9.1 4.6 2.7 3 0 0 3 3 3 0 Sigma-70, non-essential region DUF4820 PF16091.5 GAM40769.1 - 5.6 6.3 7.7 0.88 8.9 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Methyltransf_31 PF13847.6 GAM40770.1 - 9e-07 28.8 0.0 1.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM40770.1 - 4.5e-06 26.3 0.2 0.00065 19.3 0.0 2.3 1 1 0 2 2 2 1 Methyltransferase small domain N6_Mtase PF02384.16 GAM40770.1 - 3.3e-05 23.3 0.1 0.00089 18.6 0.1 2.2 1 1 0 1 1 1 1 N-6 DNA Methylase PrmA PF06325.13 GAM40770.1 - 0.00046 19.7 0.0 0.0007 19.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PrmC_N PF17827.1 GAM40770.1 - 0.00076 20.0 0.3 0.0039 17.8 0.1 2.3 2 0 0 2 2 2 1 PrmC N-terminal domain Methyltransf_25 PF13649.6 GAM40770.1 - 0.0023 18.6 0.0 0.0063 17.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 GAM40770.1 - 0.0031 16.9 0.0 0.015 14.7 0.0 1.9 1 1 0 1 1 1 1 RNA methyltransferase AviRa PF11599.8 GAM40770.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Ubie_methyltran PF01209.18 GAM40770.1 - 0.089 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAM40770.1 - 0.1 13.3 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain tRNA-synt_1b PF00579.25 GAM40771.1 - 5.4e-76 255.7 0.0 7.5e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Asp PF00026.23 GAM40771.1 - 3.2e-57 194.3 3.3 5.3e-57 193.6 3.3 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM40771.1 - 1.2e-06 28.9 1.1 3.7e-06 27.3 0.6 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAM40771.1 - 0.02 15.5 0.0 3.4 8.4 0.0 2.7 2 0 0 2 2 2 0 Aspartyl protease Ribosomal_S10 PF00338.22 GAM40772.1 - 7.5e-30 103.1 0.0 1.9e-28 98.5 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e PNP_UDP_1 PF01048.20 GAM40773.1 - 5.7e-54 182.8 0.0 7.4e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Fcf2 PF08698.11 GAM40774.1 - 3.4e-36 123.5 0.3 3.4e-36 123.5 0.3 1.8 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing CBFD_NFYB_HMF PF00808.23 GAM40775.1 - 4.4e-19 68.5 0.6 7.5e-19 67.8 0.6 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAM40775.1 - 6.1e-16 59.0 0.2 1.2e-15 58.0 0.2 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 GAM40775.1 - 0.0076 16.5 0.2 0.038 14.3 0.1 2.3 1 1 0 1 1 1 1 CENP-S associating Centromere protein X Sec15 PF04091.12 GAM40776.1 - 5.4e-112 374.3 1.9 5.4e-112 374.3 1.9 2.4 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 GAM40776.1 - 4.9e-05 23.2 3.9 4.9e-05 23.2 3.9 2.6 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain COG5 PF10392.9 GAM40776.1 - 0.00067 19.8 9.8 0.0095 16.1 5.4 3.4 2 1 1 3 3 3 1 Golgi transport complex subunit 5 COG2 PF06148.11 GAM40776.1 - 0.0029 17.7 5.6 0.0029 17.7 5.6 2.7 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.6 GAM40776.1 - 0.0053 16.6 10.4 0.036 13.9 3.5 3.0 2 1 0 2 2 2 2 Exocyst complex component Sec5 Vps51 PF08700.11 GAM40776.1 - 0.042 13.9 4.5 0.12 12.4 1.6 3.2 2 0 0 2 2 2 0 Vps51/Vps67 Mre11_DNA_bind PF04152.14 GAM40776.1 - 0.05 13.9 1.3 0.33 11.2 0.0 2.9 3 0 0 3 3 3 0 Mre11 DNA-binding presumed domain PUB PF09409.10 GAM40776.1 - 0.076 13.0 0.1 1.9 8.5 0.0 3.0 2 0 0 2 2 2 0 PUB domain KELK PF15796.5 GAM40776.1 - 0.12 12.8 2.1 0.81 10.2 1.0 2.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Vps54_N PF10475.9 GAM40776.1 - 0.14 11.4 11.4 0.046 13.0 7.5 2.0 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex DUF3510 PF12022.8 GAM40776.1 - 0.74 10.2 7.2 16 5.9 0.0 3.9 2 2 2 4 4 4 0 Domain of unknown function (DUF3510) MitMem_reg PF13012.6 GAM40776.1 - 2.5 8.6 10.8 0.53 10.7 0.2 3.9 3 1 1 4 4 4 0 Maintenance of mitochondrial structure and function RRM_2 PF04059.12 GAM40777.1 - 1.4e-31 108.5 1.5 2.8e-16 59.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif 2 RRM_1 PF00076.22 GAM40777.1 - 1.3e-06 28.1 0.1 0.19 11.5 0.1 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AhpC-TSA_2 PF13911.6 GAM40778.1 - 3.3e-08 33.6 0.0 5.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 GAM40778.1 - 3.3e-07 30.2 0.0 4.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAM40778.1 - 5.7e-05 22.9 0.0 8.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin adh_short PF00106.25 GAM40779.1 - 1.1e-36 126.1 0.5 1.4e-36 125.8 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40779.1 - 1.2e-28 100.2 0.8 4e-28 98.5 0.7 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40779.1 - 7e-16 58.6 0.1 9.5e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM40779.1 - 0.00099 18.3 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAM40779.1 - 0.0088 15.5 0.8 0.091 12.2 0.8 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.13 GAM40779.1 - 0.015 15.2 0.0 0.069 13.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family 3HCDH_N PF02737.18 GAM40779.1 - 0.056 13.3 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.8 GAM40779.1 - 0.15 11.9 0.8 0.29 10.9 0.8 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Phosphodiest PF01663.22 GAM40780.1 - 5.6e-11 42.6 0.7 1.1e-07 31.7 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 GAM40780.1 - 0.0069 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 GAM40780.1 - 0.0094 15.4 0.1 0.097 12.0 0.0 2.1 2 0 0 2 2 2 1 Sulfatase Inhibitor_G39P PF11417.8 GAM40780.1 - 0.11 13.1 0.1 0.37 11.4 0.1 1.9 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P DUF2423 PF10338.9 GAM40781.1 - 3.5e-22 78.4 1.0 3.5e-22 78.4 1.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Peroxin-3 PF04882.12 GAM40781.1 - 0.15 11.0 12.1 0.17 10.8 12.1 1.0 1 0 0 1 1 1 0 Peroxin-3 Orf78 PF06024.12 GAM40781.1 - 1.8 8.9 4.4 2.9 8.2 4.2 1.5 1 1 0 1 1 1 0 Orf78 (ac78) CDC45 PF02724.14 GAM40781.1 - 1.9 6.6 9.0 2 6.6 9.0 1.0 1 0 0 1 1 1 0 CDC45-like protein PINIT PF14324.6 GAM40782.1 - 2.8e-42 144.5 0.2 4.9e-42 143.7 0.2 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 GAM40782.1 - 5.6e-23 80.4 6.8 9.6e-23 79.7 6.8 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 GAM40782.1 - 5.4e-08 32.4 0.4 3.4e-07 29.9 0.1 2.3 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.8 GAM40782.1 - 1e-06 28.4 3.1 2.3e-06 27.3 3.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.15 GAM40782.1 - 0.091 12.8 2.8 0.26 11.4 2.8 1.8 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-C3HC4_4 PF15227.6 GAM40782.1 - 1.2 9.3 5.8 2.4 8.4 5.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FA_hydroxylase PF04116.13 GAM40783.1 - 2.7e-25 89.2 17.6 2.7e-25 89.2 17.6 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily adh_short PF00106.25 GAM40784.1 - 1.6e-42 145.2 1.0 2.2e-42 144.8 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40784.1 - 9.2e-32 110.5 0.1 1.1e-31 110.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40784.1 - 4.4e-10 39.8 0.6 1.1e-09 38.4 0.7 1.5 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 GAM40784.1 - 5.6e-08 32.5 0.0 6.9e-06 25.6 0.0 2.6 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 GAM40784.1 - 1e-05 25.5 0.1 1.5e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM40784.1 - 0.00017 21.1 0.1 0.00062 19.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAM40784.1 - 0.00034 20.2 0.2 0.00052 19.6 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family Rossmann-like PF10727.9 GAM40784.1 - 0.0081 16.0 0.6 0.025 14.4 0.6 1.9 1 0 0 1 1 1 1 Rossmann-like domain Sacchrp_dh_NADP PF03435.18 GAM40784.1 - 0.013 15.7 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 GAM40784.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GDP_Man_Dehyd PF16363.5 GAM40784.1 - 0.02 14.3 0.1 0.078 12.4 0.1 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 GAM40784.1 - 0.022 15.3 0.2 0.067 13.8 0.2 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 GAM40784.1 - 0.053 13.2 0.1 0.084 12.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 GAM40784.1 - 0.058 13.3 0.1 0.088 12.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.32 GAM40785.1 - 2e-61 202.5 14.4 1.4e-09 38.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM40785.1 - 9.8e-20 70.7 0.1 3.3e-05 24.1 0.0 6.4 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 GAM40785.1 - 5.8e-18 65.0 9.9 1e-17 64.2 9.9 1.4 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 GAM40785.1 - 9.6e-09 35.0 0.0 0.048 13.0 0.0 5.2 4 1 2 6 6 6 3 WD40-like domain Nup160 PF11715.8 GAM40785.1 - 4.7e-06 25.5 0.1 0.27 9.8 0.0 3.4 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAM40785.1 - 1.7e-05 24.0 0.1 0.57 9.1 0.0 4.5 1 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 GAM40785.1 - 5.4e-05 21.9 0.6 0.00044 18.9 0.3 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 GAM40785.1 - 0.00093 19.1 0.0 0.079 12.8 0.0 3.0 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 GAM40785.1 - 0.034 13.5 0.1 7 5.9 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal TPX2 PF06886.11 GAM40785.1 - 1.1 9.5 5.0 2.4 8.4 5.0 1.5 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) UPF0242 PF06785.11 GAM40785.1 - 1.4 9.0 6.0 1.9 8.5 6.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-C2H2 PF00096.26 GAM40786.1 - 6.1e-14 51.6 37.2 6.2e-05 23.2 1.6 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM40786.1 - 1.2e-11 44.4 27.1 7e-08 32.6 1.8 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAM40786.1 - 0.00029 21.4 6.8 0.0023 18.6 1.1 6.1 6 0 0 6 6 6 3 C2H2-type zinc finger Anth_synt_I_N PF04715.13 GAM40786.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region zf-C2H2_11 PF16622.5 GAM40786.1 - 0.82 9.5 10.2 0.26 11.1 0.4 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 GAM40786.1 - 1.1 9.7 8.1 3.6 8.1 0.8 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 GAM40786.1 - 1.6 8.8 9.6 14 5.8 0.3 4.2 2 1 1 4 4 4 0 Aberrant zinc-finger Tom7 PF08038.12 GAM40787.1 - 4.4e-08 32.7 0.8 7.6e-05 22.3 0.1 2.5 2 1 0 2 2 2 2 TOM7 family RRM_1 PF00076.22 GAM40788.1 - 4.4e-34 116.1 0.0 7.5e-16 57.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM40788.1 - 0.0019 17.8 0.1 0.074 12.6 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM40788.1 - 0.0029 17.7 0.0 0.029 14.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 GAM40788.1 - 0.01 15.5 0.5 1.1 9.0 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Cas_Cas2CT1978 PF09707.10 GAM40788.1 - 0.018 15.1 0.0 3.8 7.7 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF2015 PF09435.10 GAM40789.1 - 1.2e-46 157.2 0.0 1.3e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 GAM40790.1 - 1e-32 113.3 0.8 1.3e-32 113.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_N PF00056.23 GAM40791.1 - 1e-44 152.0 0.0 1.5e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 GAM40791.1 - 9.2e-44 149.3 0.0 1.3e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 GAM40791.1 - 0.00018 20.6 0.0 0.0003 19.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 GAM40791.1 - 0.027 14.0 0.0 3 7.4 0.0 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.19 GAM40791.1 - 0.063 12.6 0.1 0.7 9.2 0.1 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 GAM40791.1 - 0.09 12.7 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding 6PF2K PF01591.18 GAM40792.1 - 4.7e-62 209.2 0.0 7.4e-62 208.6 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase TRAPP PF04051.16 GAM40792.1 - 2.4e-44 150.6 0.0 8.9e-44 148.7 0.0 1.9 2 0 0 2 2 2 1 Transport protein particle (TRAPP) component WD40 PF00400.32 GAM40792.1 - 1.3e-32 111.3 19.8 1.2e-06 29.1 0.2 10.2 10 0 0 10 10 10 7 WD domain, G-beta repeat His_Phos_1 PF00300.22 GAM40792.1 - 9.9e-16 58.0 2.0 3e-15 56.4 0.7 2.3 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) ANAPC4_WD40 PF12894.7 GAM40792.1 - 2.8e-12 46.8 2.5 0.34 11.2 0.0 7.0 6 2 0 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM40792.1 - 0.042 12.8 1.7 3.9 6.3 0.0 3.5 3 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 GAM40792.1 - 0.15 12.1 0.0 4.1 7.5 0.0 3.5 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region KTI12 PF08433.10 GAM40792.1 - 0.16 11.4 0.5 0.36 10.2 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SBBP PF06739.11 GAM40792.1 - 0.47 10.5 2.3 9.2 6.4 1.8 2.9 2 0 0 2 2 2 0 Beta-propeller repeat Porin_3 PF01459.22 GAM40793.1 - 6.4e-84 281.6 0.1 7.5e-84 281.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.10 GAM40793.1 - 0.01 15.6 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.25 GAM40794.1 - 6.9e-66 222.3 0.0 8.1e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM40794.1 - 1.4e-25 90.0 0.0 1.9e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM40794.1 - 1.3e-06 27.9 0.0 1.3e-05 24.7 0.0 2.0 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 GAM40794.1 - 0.0017 18.3 0.9 0.012 15.6 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM40794.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 GAM40794.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIF4G_like PF09088.11 GAM40795.1 - 9.6e-90 299.5 0.1 3.3e-89 297.7 0.1 1.9 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.11 GAM40795.1 - 7e-74 248.6 0.0 1.2e-73 247.9 0.0 1.4 1 0 0 1 1 1 1 MIF4G like ABC_tran PF00005.27 GAM40796.1 - 3e-16 60.2 0.3 2.1e-15 57.4 0.3 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM40796.1 - 3.4e-10 40.2 4.7 0.00011 22.1 0.9 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM40796.1 - 0.00055 19.4 0.1 0.24 10.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM40796.1 - 0.00066 19.4 0.8 0.0014 18.3 0.8 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 GAM40796.1 - 0.0022 17.8 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.8 GAM40796.1 - 0.0034 15.0 0.3 0.0047 14.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_23 PF13476.6 GAM40796.1 - 0.0076 16.8 0.2 0.012 16.1 0.2 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GAM40796.1 - 0.011 15.7 0.2 0.017 15.0 0.2 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 GAM40796.1 - 0.015 15.1 0.1 0.02 14.6 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 GAM40796.1 - 0.026 14.7 0.1 0.046 14.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAM40796.1 - 0.03 14.7 0.3 0.054 13.9 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 GAM40796.1 - 0.032 13.8 0.1 0.061 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 GAM40796.1 - 0.082 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA PF00004.29 GAM40796.1 - 0.084 13.3 0.3 0.56 10.6 0.3 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 GAM40796.1 - 0.11 11.1 0.1 0.14 10.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 GAM40796.1 - 0.11 11.9 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM40796.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 GAM40796.1 - 0.14 12.4 0.4 0.35 11.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 GAM40796.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 GAM40796.1 - 0.2 11.6 0.6 0.91 9.5 0.2 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 GAM40796.1 - 0.24 11.1 0.1 0.39 10.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain IPPT PF01715.17 GAM40797.1 - 1.1e-41 143.2 6.4 1.2e-32 113.6 4.9 2.4 1 1 1 2 2 2 2 IPP transferase AAA_33 PF13671.6 GAM40797.1 - 5.9e-05 23.2 1.8 0.004 17.3 0.2 3.3 2 1 0 2 2 2 1 AAA domain zf-met PF12874.7 GAM40797.1 - 0.00092 19.5 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type IPT PF01745.16 GAM40797.1 - 0.0013 18.1 0.1 0.0032 16.9 0.0 1.7 2 0 0 2 2 2 1 Isopentenyl transferase AAA_18 PF13238.6 GAM40797.1 - 0.0017 18.9 2.4 0.022 15.3 1.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM40797.1 - 0.005 17.2 0.0 0.016 15.6 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain zf-C2H2_jaz PF12171.8 GAM40797.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding SEO_N PF14576.6 GAM40797.1 - 0.024 13.8 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Sieve element occlusion N-terminus AAA_22 PF13401.6 GAM40797.1 - 0.074 13.3 0.5 0.77 10.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 GAM40797.1 - 0.17 12.3 0.0 0.58 10.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAM40797.1 - 0.67 10.2 3.6 3.3 7.9 0.0 3.4 3 1 1 4 4 4 0 AAA domain RAI1 PF08652.11 GAM40798.1 - 1.4e-26 92.4 0.1 2.7e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF410 PF04190.13 GAM40799.1 - 3.3e-87 292.5 0.0 4e-87 292.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Menin PF05053.13 GAM40800.1 - 0.34 9.2 3.8 0.36 9.1 3.8 1.2 1 0 0 1 1 1 0 Menin DUF2981 PF11200.8 GAM40800.1 - 0.43 10.3 5.1 0.59 9.8 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) NST1 PF13945.6 GAM40800.1 - 0.79 9.8 9.3 1.4 9.0 9.3 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator AXIN1_TNKS_BD PF16646.5 GAM40800.1 - 2.2 9.3 10.5 0.58 11.1 2.9 3.0 2 2 0 2 2 2 0 Axin-1 tankyrase binding domain adh_short PF00106.25 GAM40801.1 - 2.3e-43 147.9 0.0 3.8e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40801.1 - 6.4e-26 91.3 0.0 1.1e-25 90.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.18 GAM40801.1 - 4.3e-15 55.5 1.0 7.2e-15 54.7 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain His_Phos_2 PF00328.22 GAM40801.1 - 1.3e-05 24.7 0.0 0.0057 16.1 0.0 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) KR PF08659.10 GAM40801.1 - 0.00094 19.1 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAM40801.1 - 0.0022 17.4 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 GAM40801.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Rep_fac_C PF08542.11 GAM40802.1 - 6e-24 84.3 0.0 1.7e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 GAM40802.1 - 3.1e-12 46.6 0.0 9e-09 35.3 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 GAM40802.1 - 6.4e-11 42.8 0.0 1.1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 GAM40802.1 - 7.9e-07 29.2 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM40802.1 - 1.6e-05 25.3 0.0 0.00055 20.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 GAM40802.1 - 2.6e-05 24.1 0.0 4.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 GAM40802.1 - 4e-05 23.4 0.0 9.8e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 GAM40802.1 - 4e-05 23.5 0.1 8.3e-05 22.5 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 GAM40802.1 - 0.00013 21.8 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 GAM40802.1 - 0.00031 21.0 0.0 0.47 10.7 0.1 2.4 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.15 GAM40802.1 - 0.0039 17.1 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 GAM40802.1 - 0.0058 16.0 0.1 0.056 12.8 0.0 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 GAM40802.1 - 0.0078 15.9 0.0 0.32 10.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 GAM40802.1 - 0.0096 16.2 0.0 0.027 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain MeaB PF03308.16 GAM40802.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_11 PF13086.6 GAM40802.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAM40802.1 - 0.018 15.4 0.1 0.12 12.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAM40802.1 - 0.053 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 NTPase TniB PF05621.11 GAM40802.1 - 0.057 12.8 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 GAM40802.1 - 0.076 12.6 0.0 0.37 10.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 GAM40802.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 GAM40802.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DEAD PF00270.29 GAM40802.1 - 0.12 12.1 0.1 5 6.9 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase HD_5 PF13487.6 GAM40802.1 - 0.17 12.2 0.0 0.48 10.7 0.0 1.8 1 0 0 1 1 1 0 HD domain AA_permease_2 PF13520.6 GAM40803.1 - 1.3e-62 212.0 43.3 1.7e-62 211.7 43.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM40803.1 - 3.1e-24 85.4 26.4 3.1e-24 85.4 26.4 2.0 2 0 0 2 2 2 1 Amino acid permease Aconitase PF00330.20 GAM40804.1 - 2.2e-111 373.1 0.4 1.7e-110 370.2 0.4 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAM40804.1 - 2.4e-25 89.4 0.0 5.2e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain FAD_binding_6 PF00970.24 GAM40804.1 - 1e-07 32.2 0.0 2.6e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GAM40804.1 - 4.1e-06 27.4 0.0 0.003 18.2 0.0 2.7 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAM40804.1 - 0.095 12.8 0.0 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Myb_DNA-binding PF00249.31 GAM40805.1 - 6.3e-32 109.5 5.7 8.5e-12 45.1 0.1 3.4 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM40805.1 - 2.4e-28 98.2 1.0 6.4e-13 48.7 0.1 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAM40805.1 - 0.0024 17.7 0.0 2 8.4 0.0 3.1 2 1 1 3 3 3 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 GAM40805.1 - 0.0029 17.9 0.1 7.3 7.0 0.1 3.0 3 0 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like SLIDE PF09111.10 GAM40805.1 - 0.0074 16.3 0.0 3.2 7.8 0.0 3.3 3 1 1 4 4 4 1 SLIDE SANT_DAMP1_like PF16282.5 GAM40805.1 - 0.048 13.9 1.5 0.44 10.8 0.1 2.5 2 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Pox_A9 PF04835.12 GAM40806.1 - 0.14 12.3 0.4 0.27 11.4 0.4 1.5 1 0 0 1 1 1 0 A9 protein conserved region FH2 PF02181.23 GAM40807.1 - 5.3e-88 295.6 6.4 5.3e-88 295.6 6.4 2.8 2 1 3 5 5 5 1 Formin Homology 2 Domain Drf_GBD PF06371.13 GAM40807.1 - 5.1e-67 225.1 0.7 1.5e-66 223.6 0.0 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 GAM40807.1 - 5e-50 169.8 7.4 6.9e-50 169.4 0.4 3.1 2 1 0 2 2 2 1 Diaphanous FH3 Domain TssO PF17561.2 GAM40807.1 - 2.3 8.3 9.8 0.078 13.1 1.1 2.7 2 0 0 2 2 2 0 Type VI secretion system, TssO CPBP PF02517.16 GAM40809.1 - 5.9e-16 58.6 6.4 5.9e-16 58.6 6.4 2.8 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease Suc_Fer-like PF06999.12 GAM40810.1 - 5.5e-55 186.3 0.0 9.2e-55 185.5 0.0 1.4 1 0 0 1 1 1 1 Sucrase/ferredoxin-like tRNA-synt_1 PF00133.22 GAM40810.1 - 1.1e-53 182.5 0.0 1.3e-21 76.5 0.0 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 GAM40810.1 - 8.7e-41 139.5 0.0 1.3e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 GAM40810.1 - 4.3e-28 98.2 0.3 2.2e-21 76.1 0.0 4.4 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 GAM40810.1 - 7.1e-12 45.5 0.0 1.3e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.19 GAM40810.1 - 0.0046 16.0 0.0 0.017 14.1 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.19 GAM40810.1 - 0.084 12.2 0.0 3.5 6.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Glyco_hydro_11 PF00457.17 GAM40811.1 - 1e-62 210.9 11.8 1.2e-62 210.6 11.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF373 PF04123.13 GAM40812.1 - 8.9 5.6 12.6 15 4.9 12.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) SET PF00856.28 GAM40813.1 - 4.5e-14 53.2 0.1 1.1e-13 51.9 0.1 1.7 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.6 GAM40813.1 - 0.11 12.7 0.1 0.38 11.1 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.19 GAM40814.1 - 6.1e-50 169.0 0.0 9.5e-50 168.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAM40814.1 - 1.4e-15 57.1 0.0 2.2e-15 56.5 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Peptidase_S78_2 PF14550.6 GAM40814.1 - 0.11 12.6 0.1 0.61 10.2 0.0 2.1 2 0 0 2 2 2 0 Putative phage serine protease XkdF PROCN PF08083.11 GAM40814.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain MnmE_helical PF12631.7 GAM40815.1 - 5.4e-31 108.4 0.0 2.3e-24 86.7 0.0 2.7 2 1 0 2 2 2 2 MnmE helical domain TrmE_N PF10396.9 GAM40815.1 - 2.1e-21 76.4 0.0 1.4e-20 73.8 0.0 2.4 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 GAM40815.1 - 1.2e-17 64.0 0.1 2.3e-17 63.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM40815.1 - 6e-08 32.5 0.1 6.7e-06 25.8 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAM40815.1 - 4.2e-05 23.1 0.1 0.00012 21.6 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAM40815.1 - 0.00011 22.3 1.2 0.00018 21.6 0.0 2.0 2 1 0 2 2 2 1 Dynamin family Glyco_hydro_3_C PF01915.22 GAM40815.1 - 0.0002 21.4 0.8 0.00035 20.6 0.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain AAA_24 PF13479.6 GAM40815.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 GAM40815.1 - 0.02 15.1 0.1 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 GAM40815.1 - 0.025 14.5 0.1 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 GAM40815.1 - 0.61 10.6 0.0 0.61 10.6 0.0 2.2 2 1 0 2 2 1 0 ABC transporter Gti1_Pac2 PF09729.9 GAM40816.1 - 2.8e-63 213.3 0.0 5.5e-63 212.3 0.0 1.5 1 0 0 1 1 1 1 Gti1/Pac2 family Sec1 PF00995.23 GAM40817.1 - 7.4e-136 454.7 0.1 8.7e-136 454.5 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Zn_clus PF00172.18 GAM40818.1 - 0.0023 18.0 5.2 0.0026 17.9 2.1 2.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrsW-protease PF13367.6 GAM40818.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 PrsW family intramembrane metalloprotease Sua5_yciO_yrdC PF01300.18 GAM40819.1 - 3e-14 52.9 0.0 1.4e-13 50.7 0.0 1.8 1 1 0 1 1 1 1 Telomere recombination MBOAT PF03062.19 GAM40820.1 - 5.8e-56 190.3 7.0 1.5e-55 189.0 7.0 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family NAD_binding_8 PF13450.6 GAM40821.1 - 2.1e-16 59.9 0.8 2.1e-16 59.9 0.8 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM40821.1 - 7e-08 32.0 0.1 2.7e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM40821.1 - 7.2e-07 29.1 2.9 2e-05 24.4 0.4 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAM40821.1 - 1.1e-05 24.9 0.1 4.3e-05 23.0 0.0 2.2 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 GAM40821.1 - 2.3e-05 23.3 1.8 0.00026 19.8 0.4 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 GAM40821.1 - 3.8e-05 24.2 0.3 0.039 14.5 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM40821.1 - 0.00011 21.5 0.9 0.00017 20.8 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 GAM40821.1 - 0.00013 22.0 0.4 0.00056 19.9 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 GAM40821.1 - 0.00033 20.0 0.1 0.0007 18.9 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 GAM40821.1 - 0.0029 17.0 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAM40821.1 - 0.061 12.4 1.8 2.4 7.2 0.0 2.9 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 GAM40821.1 - 0.068 12.2 0.2 0.11 11.5 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 GAM40821.1 - 0.25 11.0 1.8 3.8 7.1 0.2 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 GAM40821.1 - 0.3 10.1 0.9 0.49 9.4 0.9 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A GIDA PF01134.22 GAM40822.1 - 3.6e-154 513.6 0.0 4.7e-154 513.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 GAM40822.1 - 2.2e-68 230.6 1.3 2.5e-68 230.4 0.2 1.6 2 0 0 2 2 2 1 GidA associated domain adh_short PF00106.25 GAM40822.1 - 1e-32 113.2 0.1 4.3e-32 111.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40822.1 - 4.3e-22 78.8 0.0 7.2e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40822.1 - 2.1e-09 37.5 0.0 4.6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 KR domain FAD_oxidored PF12831.7 GAM40822.1 - 7.3e-06 25.6 0.5 7.3e-06 25.6 0.5 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM40822.1 - 5.4e-05 22.6 0.2 0.00011 21.6 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 GAM40822.1 - 0.00012 21.6 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_2 PF00890.24 GAM40822.1 - 0.0054 15.9 3.2 0.0054 15.9 3.2 2.0 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 GAM40822.1 - 0.0096 15.2 0.1 0.02 14.2 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 GAM40822.1 - 0.024 13.7 0.1 0.047 12.7 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein YjeF_N PF03853.15 GAM40822.1 - 0.026 14.4 0.2 9.7 6.0 0.2 2.5 2 0 0 2 2 2 0 YjeF-related protein N-terminus DapB_N PF01113.20 GAM40822.1 - 0.051 13.7 0.1 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus TPP_enzyme_M PF00205.22 GAM40822.1 - 0.17 11.6 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain RmlD_sub_bind PF04321.17 GAM40822.1 - 0.19 10.8 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain HI0933_like PF03486.14 GAM40822.1 - 0.36 9.5 3.2 0.38 9.4 0.8 2.1 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 GAM40822.1 - 1.2 8.6 4.2 10 5.6 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase ARD PF03079.14 GAM40823.1 - 4.8e-44 150.3 0.1 5.7e-44 150.1 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 GAM40823.1 - 3.1e-09 36.4 0.0 5.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 GAM40823.1 - 8.4e-05 22.5 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 GAM40823.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Tyr-DNA_phospho PF06087.12 GAM40824.1 - 4.3e-102 342.2 0.0 5.5e-102 341.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 GAM40824.1 - 2.2e-05 24.4 0.0 0.0023 17.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.20 GAM40824.1 - 0.0003 20.5 12.0 0.00089 19.0 2.2 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif ABC2_membrane PF01061.24 GAM40825.1 - 1.3e-81 273.0 53.4 1.1e-42 145.8 29.4 3.3 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 GAM40825.1 - 2.9e-36 125.0 0.0 4.1e-18 66.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAM40825.1 - 2.8e-28 97.6 4.1 5.9e-25 87.0 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 GAM40825.1 - 2.5e-13 50.4 0.6 7e-13 49.0 0.6 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 GAM40825.1 - 1.4e-05 25.1 0.1 0.00082 19.3 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 GAM40825.1 - 2.2e-05 25.0 0.0 0.00061 20.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM40825.1 - 2.6e-05 24.7 0.1 0.0046 17.4 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 GAM40825.1 - 4.6e-05 23.4 0.3 0.02 14.7 0.0 2.4 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 GAM40825.1 - 6.2e-05 23.2 0.0 0.0055 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 GAM40825.1 - 7.9e-05 22.3 0.0 0.0024 17.5 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 GAM40825.1 - 0.00018 21.8 0.2 0.048 13.9 0.0 3.8 4 1 1 5 5 4 1 AAA domain MMR_HSR1 PF01926.23 GAM40825.1 - 0.0003 20.8 0.1 0.095 12.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 GAM40825.1 - 0.00087 19.6 0.0 0.003 17.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAM40825.1 - 0.0011 18.7 0.0 0.099 12.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 GAM40825.1 - 0.002 17.8 0.3 0.49 10.2 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 GAM40825.1 - 0.0032 17.1 0.2 0.35 10.4 0.1 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 GAM40825.1 - 0.0047 16.9 0.4 0.27 11.2 0.2 2.5 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.19 GAM40825.1 - 0.014 14.9 0.5 0.092 12.2 0.1 2.3 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain TsaE PF02367.17 GAM40825.1 - 0.039 13.9 0.4 0.55 10.2 0.2 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 GAM40825.1 - 0.04 14.3 3.2 0.91 10.0 0.1 2.9 3 0 0 3 3 2 0 AAA domain Septin PF00735.18 GAM40825.1 - 0.054 12.8 0.2 0.54 9.5 0.1 2.2 2 0 0 2 2 2 0 Septin AAA_30 PF13604.6 GAM40825.1 - 0.099 12.3 2.0 2.7 7.7 0.2 2.8 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 GAM40825.1 - 0.15 11.4 0.6 6.5 6.0 0.2 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 GAM40825.1 - 0.18 11.9 0.1 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Dynamin family NB-ARC PF00931.22 GAM40825.1 - 0.19 10.9 1.3 4.3 6.4 0.2 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA PF00004.29 GAM40825.1 - 0.21 12.0 0.2 12 6.4 0.1 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 GAM40825.1 - 0.21 10.8 0.8 1.1 8.5 0.4 2.1 2 0 0 2 2 2 0 Zeta toxin MMM1 PF10296.9 GAM40826.1 - 3.1e-136 453.8 0.0 3.6e-136 453.6 0.0 1.0 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 SARAF PF06682.12 GAM40827.1 - 2.3e-94 316.7 0.1 3.3e-94 316.3 0.1 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF1523 PF07509.11 GAM40827.1 - 0.026 13.9 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1523) SUR7 PF06687.12 GAM40827.1 - 0.12 12.0 0.7 0.22 11.1 0.7 1.4 1 1 0 1 1 1 0 SUR7/PalI family Fungus-induced PF10917.8 GAM40827.1 - 2.7 8.4 8.3 4.1 7.8 6.5 2.3 1 1 1 2 2 2 0 Fungus-induced protein Myb_DNA-bind_7 PF15963.5 GAM40828.1 - 6.3e-29 99.7 0.2 6.3e-29 99.7 0.2 2.2 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 GAM40828.1 - 3.9e-08 33.3 0.0 7.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM40828.1 - 0.018 15.3 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain ABC1 PF03109.16 GAM40829.1 - 2.2e-34 118.2 2.5 3.8e-34 117.4 0.0 2.9 4 0 0 4 4 4 1 ABC1 family BRE1 PF08647.11 GAM40829.1 - 2.4e-27 94.9 13.6 2.4e-27 94.9 13.6 6.8 5 1 1 6 6 6 1 BRE1 E3 ubiquitin ligase DUF2935 PF11155.8 GAM40829.1 - 0.00074 19.8 0.0 1.1 9.6 0.0 4.3 1 1 1 2 2 2 1 Domain of unknown function (DUF2935) HALZ PF02183.18 GAM40829.1 - 0.018 15.2 21.8 4.3 7.6 0.1 7.7 7 0 0 7 7 7 0 Homeobox associated leucine zipper AMPK1_CBM PF16561.5 GAM40830.1 - 4.2e-29 100.6 0.2 7e-29 99.9 0.2 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 GAM40830.1 - 1.3e-24 86.3 1.0 4.1e-24 84.6 1.0 2.0 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain Peptidase_M22 PF00814.25 GAM40831.1 - 5.8e-84 282.0 0.0 7.2e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 GAM40831.1 - 0.12 12.0 0.1 0.63 9.6 0.1 1.9 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus SET PF00856.28 GAM40832.1 - 6.3e-21 75.5 0.0 1.7e-20 74.1 0.0 1.7 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 GAM40832.1 - 1.3e-16 61.4 4.9 2.4e-16 60.6 2.9 2.1 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding DUF3808 PF10300.9 GAM40832.1 - 0.13 11.0 0.7 0.19 10.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) EPL1 PF10513.9 GAM40833.1 - 1.1e-22 81.1 0.4 1.1e-22 81.1 0.4 3.1 2 1 0 2 2 2 1 Enhancer of polycomb-like THOC7 PF05615.13 GAM40833.1 - 0.015 15.5 4.6 0.015 15.5 4.6 3.1 3 0 0 3 3 3 0 Tho complex subunit 7 Med15 PF09606.10 GAM40833.1 - 1 7.9 16.4 1.9 7.1 16.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.6 GAM40833.1 - 3.2 8.2 9.7 0.9 10.0 5.2 2.2 2 0 0 2 2 2 0 AAA domain EF-hand_1 PF00036.32 GAM40834.1 - 4e-28 94.8 11.7 1.3e-08 33.8 1.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAM40834.1 - 9.2e-23 80.5 5.9 1.1e-13 51.4 1.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAM40834.1 - 2.7e-21 73.6 6.1 0.00012 21.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAM40834.1 - 2.9e-19 67.6 10.8 1.6e-07 30.5 0.7 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GAM40834.1 - 9.4e-14 51.0 12.5 3.3e-05 23.7 0.6 4.7 3 1 2 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAM40834.1 - 4.7e-06 26.9 0.0 0.0044 17.3 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAM40834.1 - 0.00012 22.0 9.0 0.13 12.2 0.4 4.0 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 GAM40834.1 - 0.039 14.3 0.1 0.57 10.5 0.0 2.5 2 1 1 3 3 3 0 EF-hand domain Glyco_hydro_cc PF11790.8 GAM40835.1 - 1.1e-61 208.5 1.3 1.7e-61 207.9 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core VPR PF00522.18 GAM40836.1 - 0.021 14.8 0.5 2.5 8.2 0.0 2.2 1 1 1 2 2 2 0 VPR/VPX protein Sdh5 PF03937.16 GAM40836.1 - 0.037 14.0 0.1 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase UCR_14kD PF02271.16 GAM40836.1 - 0.039 13.9 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Fungal_trans PF04082.18 GAM40837.1 - 1e-11 44.4 0.0 1.8e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40837.1 - 4.4e-10 39.5 10.1 8.2e-10 38.7 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.6 GAM40838.1 - 6.9e-20 72.5 0.0 1.3e-19 71.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAM40838.1 - 1.3e-13 51.1 0.0 7.2e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM40838.1 - 9.7e-07 28.6 0.1 2e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.20 GAM40838.1 - 0.06 13.5 0.1 0.18 11.9 0.1 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 GAM40838.1 - 0.17 11.3 0.1 0.17 11.3 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GMC_oxred_N PF00732.19 GAM40840.1 - 8.6e-64 215.7 0.0 1.1e-63 215.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM40840.1 - 4.3e-36 124.6 0.0 6.8e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 GAM40840.1 - 2.1e-06 27.6 6.3 6.7e-05 22.6 6.1 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAM40840.1 - 1.4e-05 24.4 0.1 3.8e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAM40840.1 - 0.00017 20.8 1.0 0.13 11.3 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAM40840.1 - 0.00051 20.2 0.1 0.0015 18.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM40840.1 - 0.00055 19.3 0.3 0.0025 17.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM40840.1 - 0.012 14.7 0.3 2.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 GAM40840.1 - 0.068 13.2 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAM40840.1 - 0.13 11.5 0.6 12 5.0 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM40840.1 - 0.17 12.5 0.5 2.2 8.9 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 GAM40840.1 - 0.19 10.2 0.0 0.32 9.5 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Ribosomal_S9 PF00380.19 GAM40841.1 - 2.4e-40 137.8 0.3 3.6e-40 137.2 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.19 GAM40842.1 - 1.4e-44 150.5 0.0 2.5e-44 149.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 GAM40842.1 - 6.4e-13 48.7 0.1 6.4e-13 48.7 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM40842.1 - 1.1e-06 28.6 0.1 1.1e-06 28.6 0.1 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM40842.1 - 2e-06 28.0 0.0 7.7e-06 26.2 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM40842.1 - 0.00079 19.6 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain OAD_gamma PF04277.13 GAM40842.1 - 3 8.5 4.8 6.8 7.4 4.8 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain NIF PF03031.18 GAM40843.1 - 1.1e-25 90.2 2.5 5.6e-25 87.9 2.5 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 GAM40843.1 - 0.089 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF705) DUF1682 PF07946.14 GAM40843.1 - 0.2 10.8 6.4 0.18 11.0 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) RRP36 PF06102.12 GAM40844.1 - 8e-50 169.0 32.5 8e-50 169.0 32.5 2.6 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 DUF2229 PF09989.9 GAM40844.1 - 0.07 12.8 3.4 0.14 11.8 3.4 1.6 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) RNA_pol_L_2 PF13656.6 GAM40846.1 - 1.2e-30 105.1 0.0 4.4e-21 74.4 0.0 2.2 1 1 1 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 GAM40846.1 - 2.2e-12 46.2 0.0 1.1e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.6 GAM40847.1 - 5.6e-06 27.0 0.5 7.8e-06 26.6 0.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 GAM40847.1 - 6.7e-05 22.9 0.3 0.00015 21.8 0.3 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) RRM_Rrp7 PF17799.1 GAM40847.1 - 0.023 14.5 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain IKKbetaNEMObind PF12179.8 GAM40847.1 - 0.12 12.5 0.0 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain DUF5301 PF17225.3 GAM40848.1 - 0.16 12.4 0.1 0.16 12.4 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5300) Abhydrolase_1 PF00561.20 GAM40849.1 - 1.8e-11 44.2 0.1 7.7e-11 42.1 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM40849.1 - 1.4e-05 24.5 0.0 3.7e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 TLD PF07534.16 GAM40850.1 - 0.11 12.7 0.0 0.36 11.0 0.0 1.8 2 0 0 2 2 2 0 TLD Cohesin_load PF10345.9 GAM40852.1 - 4.2e-171 570.4 9.0 5.3e-171 570.1 9.0 1.0 1 0 0 1 1 1 1 Cohesin loading factor FliS_cochap PF16522.5 GAM40852.1 - 0.035 14.1 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 Flagellar FLiS export co-chaperone, HP1076 Telomere_reg-2 PF10193.9 GAM40852.1 - 0.1 13.0 4.4 0.19 12.2 0.4 3.0 2 0 0 2 2 2 0 Telomere length regulation protein Histone PF00125.24 GAM40853.1 - 3.7e-42 143.8 2.7 1.5e-41 141.8 2.7 1.9 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GAM40853.1 - 0.0004 20.5 0.0 0.00072 19.6 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAM40853.1 - 0.0018 18.6 0.1 0.0029 18.0 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 GAM40853.1 - 0.069 13.4 0.5 0.14 12.5 0.5 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone adh_short PF00106.25 GAM40854.1 - 1.1e-41 142.4 0.1 1.4e-41 142.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40854.1 - 1.4e-32 113.2 0.0 2.1e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40854.1 - 1.5e-11 44.6 0.0 1.9e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM40854.1 - 8.4e-05 22.1 0.0 0.00015 21.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 GAM40854.1 - 0.16 11.3 0.0 0.69 9.2 0.0 2.0 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Gly_transf_sug PF04488.15 GAM40855.1 - 8.6e-21 74.4 0.1 1.8e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif SCIMP PF15050.6 GAM40855.1 - 0.078 13.4 2.2 0.14 12.6 2.2 1.4 1 0 0 1 1 1 0 SCIMP protein TcdA_TcdB PF12919.7 GAM40855.1 - 0.2 10.9 2.8 0.61 9.3 0.3 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain IGPD PF00475.18 GAM40857.1 - 3.5e-56 189.5 0.4 5.9e-56 188.8 0.5 1.3 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase Arena_RNA_pol PF06317.11 GAM40857.1 - 0.22 8.7 0.0 0.28 8.3 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase LRR_6 PF13516.6 GAM40859.1 - 0.029 14.4 4.6 31 5.0 0.0 6.3 8 0 0 8 8 8 0 Leucine Rich repeat PH PF00169.29 GAM40859.1 - 0.071 13.6 0.0 0.83 10.2 0.0 2.5 1 1 0 1 1 1 0 PH domain DUF4808 PF16066.5 GAM40859.1 - 3.9 8.1 6.8 0.48 11.0 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) Pet127 PF08634.10 GAM40860.1 - 9.5e-122 405.7 1.6 1.8e-121 404.7 1.6 1.5 1 0 0 1 1 1 1 Mitochondrial protein Pet127 GARS_A PF01071.19 GAM40861.1 - 1.3e-82 276.3 0.1 4.7e-82 274.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 GAM40861.1 - 2.9e-34 117.7 0.0 1.1e-33 115.8 0.0 2.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 GAM40861.1 - 1.2e-29 103.4 0.0 3.5e-29 101.9 0.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 GAM40861.1 - 1.5e-25 89.2 1.6 3.2e-25 88.2 0.4 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 GAM40861.1 - 1.7e-14 54.2 2.4 6.6e-14 52.3 2.4 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 GAM40861.1 - 0.00025 20.6 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 GAM40861.1 - 0.00078 19.5 0.1 0.0025 17.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 GAM40861.1 - 0.0013 18.3 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 GAM40861.1 - 0.032 13.8 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Actin PF00022.19 GAM40862.1 - 3.8e-150 500.0 0.0 2.2e-149 497.5 0.0 2.1 2 1 0 2 2 2 1 Actin Fes1 PF08609.10 GAM40863.1 - 5e-29 101.0 2.9 5e-29 101.0 2.9 1.9 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_EZ PF13513.6 GAM40863.1 - 2.6e-10 40.6 0.4 6.6e-09 36.1 0.0 2.5 2 0 0 2 2 2 1 HEAT-like repeat Arm PF00514.23 GAM40863.1 - 1e-07 31.7 0.3 0.0055 16.7 0.0 2.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 GAM40863.1 - 2.2e-07 30.6 0.1 0.052 13.8 0.0 3.2 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 GAM40863.1 - 5.3e-06 26.7 0.3 1.6e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 HEAT repeats AIRC PF00731.20 GAM40863.1 - 0.063 12.8 0.0 0.42 10.2 0.0 2.0 1 1 0 1 1 1 0 AIR carboxylase DUF3458_C PF17432.2 GAM40863.1 - 0.065 12.6 0.5 0.22 10.8 0.1 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF3458_C) ARM repeats V-ATPase_H_C PF11698.8 GAM40863.1 - 0.075 13.1 0.1 0.61 10.2 0.0 2.0 1 1 1 2 2 2 0 V-ATPase subunit H V-ATPase_H_N PF03224.14 GAM40863.1 - 0.098 11.9 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 V-ATPase subunit H UPF0220 PF05255.11 GAM40864.1 - 9.3e-72 240.0 4.6 1e-71 239.8 4.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Proteasome PF00227.26 GAM40865.1 - 9.2e-49 165.5 0.1 1.2e-48 165.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAM40865.1 - 3.1e-12 45.9 0.3 5e-12 45.3 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2862 PF11061.8 GAM40865.1 - 0.07 13.0 0.0 0.23 11.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2862) Lysine_decarbox PF03641.14 GAM40866.1 - 9.8e-29 100.1 0.0 2.1e-28 99.1 0.0 1.5 1 1 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 GAM40866.1 - 0.0031 17.1 0.7 0.033 13.8 0.1 2.2 2 0 0 2 2 2 1 SLOG cluster4 family DAGK_cat PF00781.24 GAM40866.1 - 0.14 11.8 0.8 4.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Med6 PF04934.14 GAM40867.1 - 3.8e-38 130.3 0.1 6.4e-38 129.6 0.1 1.4 1 0 0 1 1 1 1 MED6 mediator sub complex component Sld7_C PF18596.1 GAM40868.1 - 1.6e-13 50.5 0.0 4.4e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Sld7 C-terminal domain Glyco_hydro_43 PF04616.14 GAM40869.1 - 8.1e-27 94.3 0.4 4.9e-24 85.2 0.2 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Cellulase PF00150.18 GAM40869.1 - 3.1e-17 62.9 0.6 4.7e-17 62.3 0.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 GAM40869.1 - 4e-06 26.7 0.7 6.5e-06 26.0 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.17 GAM40869.1 - 0.0043 16.2 0.0 0.01 14.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 GAM40869.1 - 0.0084 15.5 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase Trs65 PF12735.7 GAM40869.1 - 0.15 11.5 1.7 0.23 10.8 1.7 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 DUF2255 PF10012.9 GAM40869.1 - 0.16 12.1 0.3 0.35 11.0 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) Mucin PF01456.17 GAM40869.1 - 8.8 6.3 23.2 27 4.8 23.2 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein MFS_1 PF07690.16 GAM40870.1 - 5.6e-33 114.3 26.6 5.6e-33 114.3 26.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM40870.1 - 0.00035 19.1 1.8 0.00068 18.2 1.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HAD_SAK_1 PF10307.9 GAM40871.1 - 8.1e-78 260.9 0.0 1.3e-77 260.3 0.0 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins zf-RING_2 PF13639.6 GAM40872.1 - 2.8e-09 37.1 4.4 4.6e-09 36.5 4.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAM40872.1 - 2.3e-07 30.5 2.1 3.4e-07 30.0 2.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAM40872.1 - 8.8e-07 29.1 2.5 2e-06 27.9 2.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAM40872.1 - 9.3e-07 28.6 2.9 1.4e-06 28.0 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM40872.1 - 9.3e-07 28.6 4.3 1.4e-06 28.0 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM40872.1 - 0.0024 17.7 3.6 0.0042 16.9 3.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAM40872.1 - 0.066 13.3 0.4 0.17 12.0 0.4 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 GAM40872.1 - 0.13 12.3 1.1 0.27 11.2 1.1 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 GAM40872.1 - 0.13 12.0 2.4 0.27 11.0 2.4 1.5 1 0 0 1 1 1 0 RING-like zinc finger MAM33 PF02330.16 GAM40873.1 - 5.2e-69 232.4 2.5 6.1e-69 232.2 2.5 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein CCB1 PF12046.8 GAM40873.1 - 0.13 11.6 0.1 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B Tma16 PF11176.8 GAM40874.1 - 5.3e-49 165.9 4.6 6.5e-49 165.6 4.6 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 MmgE_PrpD PF03972.14 GAM40874.1 - 0.0031 16.1 0.1 0.004 15.8 0.1 1.1 1 0 0 1 1 1 1 MmgE/PrpD family Ins_P5_2-kin PF06090.12 GAM40874.1 - 0.032 13.7 0.1 0.034 13.6 0.1 1.2 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase HTH_32 PF13565.6 GAM40874.1 - 1.8 9.2 8.9 0.36 11.5 4.8 2.0 2 1 0 2 2 2 0 Homeodomain-like domain XPG_I PF00867.18 GAM40875.1 - 4.3e-23 81.5 0.0 9.7e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 GAM40875.1 - 7.8e-23 80.9 0.0 1.7e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 GAM40875.1 - 0.00082 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 GAM40875.1 - 0.12 13.0 0.0 0.47 11.1 0.0 1.9 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Fig1 PF12351.8 GAM40876.1 - 4.5e-57 193.0 5.2 4.5e-57 193.0 5.2 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 GAM40876.1 - 5.9e-07 29.3 7.3 7.9e-07 28.9 7.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 GAM40876.1 - 0.0016 17.6 3.3 0.0016 17.6 3.3 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) SAM_adeno_trans PF01887.16 GAM40876.1 - 0.041 13.3 0.1 0.057 12.9 0.1 1.2 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase DUF751 PF05421.11 GAM40876.1 - 0.98 10.2 0.0 0.98 10.2 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF751) Ferlin_C PF16165.5 GAM40876.1 - 2.3 8.2 3.5 2.2 8.2 0.3 2.3 2 0 0 2 2 2 0 Ferlin C-terminus DUF2207 PF09972.9 GAM40876.1 - 8.7 5.0 18.5 20 3.8 9.9 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Ras PF00071.22 GAM40877.1 - 1.1e-07 31.5 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Ras family zf-BED PF02892.15 GAM40877.1 - 0.038 14.0 2.3 0.65 10.1 0.5 2.8 2 0 0 2 2 2 0 BED zinc finger Epimerase PF01370.21 GAM40878.1 - 9.7e-11 41.6 0.2 1.1e-09 38.1 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM40878.1 - 1.1e-07 32.0 0.1 1.5e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAM40878.1 - 4.9e-06 25.8 0.1 1.1e-05 24.6 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAM40878.1 - 7.5e-05 22.0 1.5 0.0037 16.5 0.1 2.7 2 1 0 2 2 2 1 Male sterility protein NmrA PF05368.13 GAM40878.1 - 9.6e-05 22.0 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 GAM40878.1 - 0.0017 17.5 0.1 0.0025 17.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAM40878.1 - 0.018 14.9 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 GAM40878.1 - 0.054 12.9 1.1 2.3 7.5 0.6 2.7 2 2 0 2 2 2 0 GDP-mannose 4,6 dehydratase Thr_synth_N PF14821.6 GAM40882.1 - 1.8e-29 101.8 0.0 5.8e-29 100.1 0.0 2.0 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 GAM40882.1 - 9.1e-18 64.7 0.0 3.3e-17 62.8 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme BCS1_N PF08740.11 GAM40883.1 - 3.1e-34 118.6 1.4 5.2e-34 117.9 0.8 1.6 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 GAM40883.1 - 3.7e-16 59.7 0.0 1.1e-07 32.4 0.0 2.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAM40883.1 - 0.0078 16.5 0.1 0.025 14.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 GAM40883.1 - 0.036 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAM40883.1 - 0.057 13.8 0.1 0.14 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 GAM40883.1 - 0.079 13.0 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 GAM40883.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC NMU PF02070.15 GAM40884.1 - 5.1 7.1 8.8 3.2 7.7 1.8 3.0 2 0 0 2 2 2 0 Neuromedin U Coatomer_WDAD PF04053.14 GAM40886.1 - 2.5e-142 475.0 0.5 6.7e-142 473.7 0.1 1.8 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 GAM40886.1 - 1.4e-106 356.6 0.1 2.1e-106 356.1 0.1 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 GAM40886.1 - 4e-40 135.1 16.5 4.5e-08 33.6 0.3 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM40886.1 - 1e-08 35.4 1.1 0.2 12.0 0.0 5.4 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM40886.1 - 0.0058 15.3 5.1 0.69 8.5 0.1 3.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Clathrin PF00637.20 GAM40886.1 - 0.25 11.2 1.6 1.2 9.0 0.0 2.7 3 1 0 3 3 3 0 Region in Clathrin and VPS Evr1_Alr PF04777.13 GAM40887.1 - 2.3e-29 101.8 2.6 2.3e-29 101.8 2.6 1.5 2 0 0 2 2 2 1 Erv1 / Alr family APOBEC4 PF18775.1 GAM40887.1 - 0.29 11.3 0.8 0.54 10.4 0.1 1.8 2 0 0 2 2 2 0 APOBEC4 DEK_C PF08766.11 GAM40888.1 - 0.0077 16.1 0.2 0.021 14.8 0.2 1.7 1 0 0 1 1 1 1 DEK C terminal domain SOG2 PF10428.9 GAM40888.1 - 4.1 6.5 8.1 5.8 6.0 8.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Glyco_transf_54 PF04666.13 GAM40889.1 - 8.7e-14 51.1 0.7 1.8e-11 43.5 0.3 2.6 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glyco_transf_25 PF01755.17 GAM40889.1 - 0.04 13.8 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Adaptin_N PF01602.20 GAM40890.1 - 1.8e-137 459.1 7.2 2.3e-137 458.7 7.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAM40890.1 - 4.1e-64 215.5 3.3 2.8e-60 203.0 1.3 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM40890.1 - 1.7e-17 63.6 5.3 1.6e-07 31.6 0.0 6.3 2 1 5 7 7 7 5 HEAT repeats HEAT PF02985.22 GAM40890.1 - 4.6e-13 48.2 2.5 0.019 15.2 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.23 GAM40890.1 - 0.00015 21.7 0.8 1.1 9.5 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 GAM40890.1 - 0.00098 18.7 0.1 3.4 7.2 0.0 3.5 2 1 1 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.6 GAM40890.1 - 0.0012 19.3 4.6 0.54 10.8 0.0 6.0 5 1 1 6 6 6 1 HEAT-like repeat Cnd3 PF12719.7 GAM40890.1 - 0.031 13.5 0.8 3.9 6.6 0.0 3.5 3 1 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain DUF2817 PF10994.8 GAM40890.1 - 0.042 13.2 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Sec7_N PF12783.7 GAM40890.1 - 0.28 11.1 1.8 0.87 9.5 0.5 2.7 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Ribosomal_60s PF00428.19 GAM40890.1 - 1.9 9.2 11.1 10 6.8 7.1 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein TBCC PF07986.12 GAM40891.1 - 1.7e-33 114.9 0.9 2.6e-33 114.3 0.9 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 GAM40891.1 - 1.6e-09 38.2 0.4 2.9e-09 37.4 0.4 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Pro-kuma_activ PF09286.11 GAM40892.1 - 3.1e-30 105.3 0.5 1.3e-29 103.3 0.2 2.3 2 1 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAM40892.1 - 2e-07 30.6 0.1 3.1e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Subtilase family PPO1_DWL PF12142.8 GAM40892.1 - 0.046 13.5 0.4 0.1 12.4 0.4 1.5 1 0 0 1 1 1 0 Polyphenol oxidase middle domain Cupin_2 PF07883.11 GAM40893.1 - 5.4e-07 29.2 0.0 9e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 GAM40893.1 - 2.7e-05 23.8 0.0 0.00012 21.7 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF861) adh_short PF00106.25 GAM40894.1 - 1.7e-16 60.2 0.3 2.5e-16 59.7 0.3 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40894.1 - 3.6e-13 49.6 0.5 1.1e-12 48.0 0.2 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40894.1 - 4.8e-08 33.1 0.6 8e-08 32.4 0.3 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 GAM40894.1 - 8.8e-06 25.7 1.4 8.8e-06 25.7 1.4 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 GAM40894.1 - 9.1e-06 25.4 2.3 1.5e-05 24.7 2.3 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAM40894.1 - 0.00027 20.5 0.2 0.0004 19.9 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 GAM40894.1 - 0.0031 17.6 1.0 0.0069 16.5 1.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 GAM40894.1 - 0.0037 16.7 0.1 0.0054 16.2 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DHO_dh PF01180.21 GAM40894.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase CSN8_PSD8_EIF3K PF10075.9 GAM40895.1 - 3.8e-18 65.9 0.0 7.6e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 GAM40895.1 - 0.00024 20.6 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family WD40 PF00400.32 GAM40896.1 - 0.013 16.4 0.2 8.5 7.4 0.0 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Vps51 PF08700.11 GAM40897.1 - 2.2e-26 91.8 0.0 5.5e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 GAM40897.1 - 0.016 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Dor1 PF04124.12 GAM40897.1 - 0.068 11.8 0.0 0.11 11.2 0.0 1.4 1 1 0 1 1 1 0 Dor1-like family FlgN PF05130.12 GAM40897.1 - 0.12 12.9 2.4 6.7 7.2 0.1 3.0 1 1 1 2 2 2 0 FlgN protein RMI1_N PF08585.12 GAM40898.1 - 5.7e-66 222.4 0.1 6.7e-66 222.1 0.1 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein TPR_2 PF07719.17 GAM40899.1 - 2.6e-28 95.8 43.4 0.0033 17.4 0.1 16.0 17 0 0 17 17 15 8 Tetratricopeptide repeat TPR_8 PF13181.6 GAM40899.1 - 6.8e-24 82.0 29.9 0.064 13.5 0.1 14.1 14 0 0 14 14 13 8 Tetratricopeptide repeat TPR_14 PF13428.6 GAM40899.1 - 1.2e-23 81.7 27.8 0.0027 18.4 0.0 16.3 14 5 5 19 19 16 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAM40899.1 - 1.7e-23 81.4 33.7 0.0081 16.0 0.1 15.1 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_19 PF14559.6 GAM40899.1 - 4.2e-23 81.6 16.0 0.0013 19.2 0.4 11.7 9 3 2 12 12 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAM40899.1 - 6.2e-23 81.2 39.2 0.00037 21.1 0.7 12.7 13 1 1 14 14 12 7 Tetratricopeptide repeat TPR_17 PF13431.6 GAM40899.1 - 7.8e-19 66.6 18.8 0.16 12.4 0.0 14.7 16 0 0 16 16 14 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM40899.1 - 1.2e-14 53.6 23.1 0.00048 19.8 0.1 8.8 9 0 0 9 9 7 4 TPR repeat TPR_12 PF13424.6 GAM40899.1 - 1.2e-13 51.1 43.2 1.4e-07 31.7 0.3 12.9 12 4 1 13 13 12 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAM40899.1 - 2.2e-13 49.2 17.6 0.0014 18.5 0.0 11.7 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM40899.1 - 1.9e-06 27.5 2.4 0.55 9.5 0.2 4.8 4 0 0 4 4 4 2 MalT-like TPR region TPR_6 PF13174.6 GAM40899.1 - 4.9e-06 26.8 22.3 0.2 12.4 0.1 11.8 14 0 0 14 14 11 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM40899.1 - 6.4e-06 26.3 15.0 4.3 7.6 0.2 7.4 6 2 1 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 GAM40899.1 - 8.9e-05 22.8 1.6 4 8.3 0.2 7.3 8 0 0 8 8 6 1 Tetratricopeptide repeat DUF2989 PF11207.8 GAM40899.1 - 0.00057 19.7 1.4 1.8 8.3 0.1 4.5 4 1 0 4 4 4 1 Protein of unknown function (DUF2989) TPR_9 PF13371.6 GAM40899.1 - 0.0019 18.3 4.7 6.2 7.1 0.0 6.4 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_22 PF18833.1 GAM40899.1 - 0.011 15.8 0.0 0.044 13.9 0.0 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM40899.1 - 0.025 14.5 15.5 0.038 13.9 0.1 7.1 8 0 0 8 8 6 0 Tetratricopeptide repeat Cas_Cas02710 PF09670.10 GAM40899.1 - 0.033 13.0 0.1 0.075 11.8 0.1 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) DUF627 PF04781.12 GAM40899.1 - 0.065 13.2 0.1 6.2 6.9 0.0 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF627) Sel1 PF08238.12 GAM40899.1 - 0.078 13.7 0.9 4.1 8.2 0.2 3.9 4 0 0 4 4 2 0 Sel1 repeat DUF2225 PF09986.9 GAM40899.1 - 0.62 9.8 3.3 4.9 6.8 0.1 3.2 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2225) FAT PF02259.23 GAM40899.1 - 0.92 8.7 10.3 7.9 5.6 0.3 4.7 5 0 0 5 5 5 0 FAT domain DUF3856 PF12968.7 GAM40899.1 - 9.8 6.2 8.8 8.2 6.5 0.0 5.0 7 1 0 7 7 4 0 Domain of Unknown Function (DUF3856) Glyco_hydro_5_C PF18564.1 GAM40900.1 - 1.7e-20 73.3 0.0 4.1e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 GAM40900.1 - 1.5e-09 37.7 6.1 6.3e-07 29.1 4.3 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) EKLF_TAD1 PF16832.5 GAM40900.1 - 0.063 13.2 0.7 0.14 12.0 0.7 1.5 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 Fungal_trans PF04082.18 GAM40901.1 - 5.2e-07 29.0 0.1 1.2e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 GAM40902.1 - 8.5e-20 71.0 0.0 1.1e-16 60.9 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40902.1 - 2.9e-13 49.9 0.1 2.9e-12 46.7 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40902.1 - 0.034 14.0 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 KR domain DHquinase_I PF01487.15 GAM40902.1 - 0.096 12.9 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Type I 3-dehydroquinase Xpo1 PF08389.12 GAM40903.1 - 3.4e-12 46.6 1.3 1.8e-10 41.1 0.8 3.8 2 1 0 2 2 2 1 Exportin 1-like protein IFRD PF05004.13 GAM40903.1 - 0.065 12.3 0.6 0.15 11.2 0.6 1.5 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 GAM40903.1 - 0.7 10.3 2.6 3.4 8.1 0.2 3.1 3 0 0 3 3 3 0 HEAT repeats 7TMR-HDED PF07697.11 GAM40903.1 - 4.1 7.5 5.7 1.7 8.7 0.3 2.9 4 0 0 4 4 4 0 7TM-HD extracellular GRIM-19 PF06212.12 GAM40904.1 - 3.4e-22 78.8 0.2 7.8e-22 77.6 0.2 1.6 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.21 GAM40905.1 - 2e-23 83.1 0.0 3.6e-22 79.0 0.0 2.3 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase NARP1 PF12569.8 GAM40905.1 - 2.8 6.8 10.2 13 4.5 7.2 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Fungal_trans PF04082.18 GAM40906.1 - 3.2e-24 85.4 0.2 6.6e-24 84.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40906.1 - 9.3e-08 32.1 10.2 1.9e-07 31.1 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.21 GAM40907.1 - 4.7e-46 157.1 0.0 5.9e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 2-Hacid_dh_C PF02826.19 GAM40908.1 - 5.6e-55 185.4 0.0 8.3e-55 184.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAM40908.1 - 2.3e-18 66.1 0.0 3.6e-18 65.5 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAM40908.1 - 2.2e-07 31.2 0.0 6.3e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 GAM40908.1 - 0.15 12.7 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 GAM40909.1 - 1.1e-32 114.0 0.0 1.3e-32 113.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM40909.1 - 4.4e-07 30.0 0.1 1.2e-06 28.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM40909.1 - 7.8e-06 25.4 0.0 2.5e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM40909.1 - 6.4e-05 22.2 0.0 0.0028 16.8 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 GAM40909.1 - 0.00013 22.0 0.0 0.039 13.9 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Glu_dehyd_C PF16912.5 GAM40909.1 - 0.0023 17.4 0.0 0.045 13.2 0.0 2.7 3 0 0 3 3 3 1 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 GAM40909.1 - 0.0034 16.7 0.0 0.076 12.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM40909.1 - 0.0051 15.9 0.0 2.7 7.0 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 GAM40909.1 - 0.0067 15.2 0.0 0.11 11.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 GAM40909.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 GAM40909.1 - 0.038 14.0 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 GAM40909.1 - 0.057 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.18 GAM40909.1 - 0.06 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 GAM40909.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 GAM40909.1 - 0.062 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 GAM40909.1 - 0.12 13.0 0.0 0.63 10.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 GAM40910.1 - 1.4e-78 264.8 25.8 1.7e-78 264.5 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM40910.1 - 6.4e-20 71.4 45.7 2.8e-16 59.4 24.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 GAM40911.1 - 4.1e-27 95.0 28.1 1.9e-14 53.3 13.0 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM40911.1 - 2.5e-11 43.1 1.1 2.5e-11 43.1 1.1 3.5 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAM40911.1 - 0.0017 16.8 0.6 0.0017 16.8 0.6 2.2 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) 60KD_IMP PF02096.20 GAM40911.1 - 0.02 14.8 0.5 0.02 14.8 0.5 2.4 2 2 0 2 2 2 0 60Kd inner membrane protein TssO PF17561.2 GAM40911.1 - 0.074 13.2 0.6 0.14 12.3 0.3 1.6 1 1 0 1 1 1 0 Type VI secretion system, TssO OATP PF03137.20 GAM40911.1 - 0.32 9.2 3.8 0.56 8.4 2.8 1.9 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4381 PF14316.6 GAM40911.1 - 2.3 8.4 5.8 0.81 9.9 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Methyltransf_25 PF13649.6 GAM40912.1 - 6.4e-05 23.6 0.0 0.00031 21.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM40912.1 - 0.00021 22.0 0.0 0.00042 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM40912.1 - 0.00028 20.7 0.0 0.00061 19.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Guanylate_cyc_2 PF09778.9 GAM40912.1 - 0.047 13.0 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Guanylylate cyclase Ubie_methyltran PF01209.18 GAM40912.1 - 0.05 12.9 0.0 14 4.9 0.0 2.9 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family TPR_12 PF13424.6 GAM40914.1 - 7.2e-30 103.1 8.0 2.6e-10 40.4 0.1 5.7 2 1 3 5 5 5 4 Tetratricopeptide repeat Asp_protease PF09668.10 GAM40914.1 - 1.4e-24 86.2 0.2 3e-24 85.2 0.2 1.5 1 0 0 1 1 1 1 Aspartyl protease TPR_10 PF13374.6 GAM40914.1 - 2.2e-22 78.2 9.2 4.8e-05 23.1 0.0 7.2 6 1 1 7 7 7 5 Tetratricopeptide repeat DUF3328 PF11807.8 GAM40914.1 - 1.3e-20 74.1 1.6 3.1e-20 72.9 1.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) TPR_1 PF00515.28 GAM40914.1 - 1.6e-13 49.8 16.3 0.0057 16.4 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAM40914.1 - 1.5e-12 46.6 12.1 0.036 14.2 0.1 5.9 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAM40914.1 - 3.2e-08 33.0 0.2 0.24 11.5 0.0 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM40914.1 - 4.6e-08 32.7 8.0 0.02 15.1 0.1 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM40914.1 - 2e-07 30.7 2.7 0.002 17.6 0.2 2.5 1 1 1 2 2 2 2 MalT-like TPR region gag-asp_proteas PF13975.6 GAM40914.1 - 1.9e-05 25.1 0.0 5.6e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease TPR_16 PF13432.6 GAM40914.1 - 8.1e-05 23.2 0.4 1.6 9.4 0.0 4.7 4 1 0 4 4 3 1 Tetratricopeptide repeat NB-ARC PF00931.22 GAM40914.1 - 0.00015 21.1 0.0 0.0003 20.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 GAM40914.1 - 0.00073 20.1 0.4 57 4.9 0.0 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_16 PF13191.6 GAM40914.1 - 0.00079 19.8 0.0 0.0022 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain TPR_17 PF13431.6 GAM40914.1 - 0.00081 19.6 1.0 51 4.6 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM40914.1 - 0.0016 18.9 4.8 0.52 10.9 0.8 4.4 2 2 1 3 3 3 1 Tetratricopeptide repeat ATPase_2 PF01637.18 GAM40914.1 - 0.016 15.1 0.0 0.077 12.9 0.0 2.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea PNP_UDP_1 PF01048.20 GAM40914.1 - 0.1 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Phosphorylase superfamily TPR_11 PF13414.6 GAM40914.1 - 0.15 11.8 2.1 1.3e+02 2.4 0.0 4.4 4 0 0 4 4 4 0 TPR repeat TPR_21 PF09976.9 GAM40914.1 - 0.16 11.7 4.7 26 4.4 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain PGF-CTERM PF18204.1 GAM40915.1 - 0.23 11.5 0.7 0.45 10.6 0.7 1.5 1 0 0 1 1 1 0 PGF-CTERM motif Ank_5 PF13857.6 GAM40916.1 - 7.4e-14 51.6 0.1 1.3e-05 25.3 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM40916.1 - 3.7e-13 49.7 0.0 0.00094 19.7 0.0 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM40916.1 - 5.4e-13 49.3 0.1 0.0082 16.7 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM40916.1 - 3.3e-10 39.3 0.2 0.015 15.8 0.0 5.1 4 1 1 5 5 5 3 Ankyrin repeat Ank PF00023.30 GAM40916.1 - 1.2e-05 25.5 0.0 2.7 8.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Asp_Glu_race PF01177.22 GAM40917.1 - 0.072 12.9 0.0 0.27 11.1 0.0 1.8 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase DUF1338 PF07063.13 GAM40918.1 - 3.4e-109 365.0 0.1 4e-109 364.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) VID27 PF08553.10 GAM40919.1 - 1.9e-195 648.9 0.0 2.7e-195 648.4 0.0 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 GAM40919.1 - 6.3e-78 260.5 0.3 6.3e-78 260.5 0.3 3.4 3 1 1 4 4 4 1 VID27 N-terminal region VID27_PH PF17747.1 GAM40919.1 - 7.1e-47 158.2 2.0 2.1e-46 156.7 0.8 2.2 2 0 0 2 2 2 1 VID27 PH-like domain UPF0149 PF03695.13 GAM40919.1 - 0.0047 17.2 6.1 0.014 15.7 3.6 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0149) TLD PF07534.16 GAM40920.1 - 1.3e-08 35.2 0.1 2.9e-06 27.6 0.0 2.6 2 0 0 2 2 2 2 TLD AIM3 PF17096.5 GAM40920.1 - 0.75 10.8 0.1 0.75 10.8 0.1 2.8 2 1 0 2 2 2 0 Altered inheritance of mitochondria protein 3 JAB PF01398.21 GAM40921.1 - 8.9e-17 61.2 0.0 2.4e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 GAM40921.1 - 7.4e-11 42.3 0.2 1.4e-10 41.3 0.2 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 GAM40921.1 - 1.8e-05 24.5 0.1 6.8e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain SurA_N_3 PF13624.6 GAM40921.1 - 0.45 10.3 2.2 0.79 9.5 0.2 2.1 2 0 0 2 2 2 0 SurA N-terminal domain Peptidase_U57 PF05582.12 GAM40922.1 - 0.071 12.4 1.7 0.13 11.5 1.7 1.4 1 0 0 1 1 1 0 YabG peptidase U57 Aldedh PF00171.22 GAM40924.1 - 3.1e-128 428.2 0.0 3.9e-128 427.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 GAM40924.1 - 0.091 12.8 1.0 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated LuxC PF05893.14 GAM40924.1 - 0.16 11.0 0.1 0.32 10.0 0.1 1.8 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Esterase_phd PF10503.9 GAM40925.1 - 0.0013 18.3 0.1 0.004 16.7 0.1 1.7 1 1 1 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.20 GAM40925.1 - 0.028 14.1 0.0 0.071 12.7 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.21 GAM40925.1 - 0.056 12.9 0.2 0.18 11.2 0.2 1.8 1 1 1 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GAM40925.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Pec_lyase_C PF00544.19 GAM40926.1 - 1.5e-15 57.4 10.2 5.1e-14 52.4 10.1 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GAM40926.1 - 0.00017 21.4 12.6 0.00043 20.2 2.6 2.4 1 1 1 2 2 2 2 Right handed beta helix region Pkinase PF00069.25 GAM40927.1 - 4e-14 52.6 0.0 1.2e-13 51.1 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 GAM40927.1 - 0.0034 16.2 0.0 0.0055 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 GAM40927.1 - 0.012 14.9 0.0 0.03 13.6 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase APH PF01636.23 GAM40927.1 - 0.034 14.0 0.1 0.14 12.1 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 GAM40927.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF2182 PF09948.9 GAM40927.1 - 5.5 6.8 5.5 1.1 9.1 1.5 1.7 2 0 0 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) Iso_dh PF00180.20 GAM40928.1 - 1.6e-71 241.3 0.0 2e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HAD_2 PF13419.6 GAM40929.1 - 1.6e-21 77.2 0.0 1.8e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM40929.1 - 4.6e-12 46.7 0.0 5.6e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM40929.1 - 0.00016 21.7 0.1 0.00055 19.9 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like D-ser_dehydrat PF14031.6 GAM40930.1 - 2.6e-22 79.3 0.0 7.5e-21 74.6 0.0 2.4 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 GAM40930.1 - 3.3e-13 49.8 0.0 4.9e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain FTHFS PF01268.19 GAM40931.1 - 2.8e-255 847.8 0.1 4.3e-255 847.2 0.1 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 GAM40931.1 - 5.1e-66 220.9 1.6 5.1e-66 220.9 1.6 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 GAM40931.1 - 3.7e-39 133.6 1.1 9.2e-39 132.3 0.9 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.27 GAM40931.1 - 0.016 14.8 0.1 0.053 13.1 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF1997 PF09366.10 GAM40931.1 - 0.19 11.8 0.0 1.7 8.8 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1997) AdoHcyase_NAD PF00670.21 GAM40931.1 - 0.44 10.6 1.9 4.7 7.2 0.4 2.8 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain WD40 PF00400.32 GAM40932.1 - 2.5e-27 94.6 0.3 1e-08 35.6 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM40932.1 - 7.5e-13 48.6 0.0 0.04 14.2 0.0 5.7 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 GAM40932.1 - 0.00028 20.7 0.1 0.00042 20.1 0.1 1.3 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 GAM40932.1 - 0.00034 19.4 0.1 0.021 13.5 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 GAM40932.1 - 0.016 14.6 0.0 1.6 8.0 0.0 2.7 2 1 0 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 GAM40932.1 - 0.025 13.6 0.5 21 3.9 0.1 3.2 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 GAM40932.1 - 0.077 12.0 0.0 2.4 7.1 0.0 2.2 1 1 1 2 2 2 0 Coatomer WD associated region PALB2_WD40 PF16756.5 GAM40932.1 - 0.13 11.2 0.2 8.5 5.2 0.1 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain MBF1 PF08523.10 GAM40933.1 - 1.2e-25 89.8 1.4 1.2e-25 89.8 1.4 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 GAM40933.1 - 1.9e-11 43.8 0.0 3.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 GAM40933.1 - 3.1e-06 27.4 0.1 1e-05 25.8 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain GATase_7 PF13537.6 GAM40934.1 - 1.5e-15 57.2 0.0 2.9e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAM40934.1 - 2.6e-15 56.8 0.0 5.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 GAM40934.1 - 3.3e-08 33.2 0.0 8.9e-08 31.8 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 GAM40934.1 - 2.7e-05 23.2 0.0 5.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PA PF02225.22 GAM40934.1 - 0.049 13.6 0.3 0.22 11.6 0.2 2.0 1 1 1 2 2 2 0 PA domain SH3_1 PF00018.28 GAM40935.1 - 1e-15 57.1 0.0 1.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAM40935.1 - 1.8e-13 50.1 0.1 5e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 GAM40935.1 - 1.7e-08 34.0 0.0 2.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Ank_2 PF12796.7 GAM40936.1 - 4.8e-24 84.7 0.6 9.6e-17 61.4 0.1 4.5 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM40936.1 - 1.9e-21 76.1 1.4 3.2e-07 30.8 0.1 5.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM40936.1 - 3.7e-18 65.4 5.8 8.9e-07 29.1 0.2 4.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 GAM40936.1 - 2e-16 59.6 2.5 0.00032 21.0 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 GAM40936.1 - 7.9e-16 56.6 3.6 0.0023 18.3 0.0 6.3 7 0 0 7 7 7 4 Ankyrin repeat AIM24 PF01987.17 GAM40937.1 - 1.3e-48 165.5 0.1 1.7e-48 165.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 KAR9 PF08580.10 GAM40937.1 - 0.9 8.0 7.5 1.1 7.7 7.5 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 TFIIA PF03153.13 GAM40937.1 - 3.7 7.5 6.2 4.6 7.1 6.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-5_eIF-2B PF01873.17 GAM40938.1 - 8.6e-41 138.5 0.1 1.4e-40 137.8 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF932 PF06067.11 GAM40938.1 - 0.17 11.6 1.1 0.85 9.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF932) TF_Zn_Ribbon PF08271.12 GAM40938.1 - 0.22 11.1 1.8 0.52 9.9 1.8 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 GAM40938.1 - 1.6 9.2 7.6 1.2 9.5 0.4 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain zf-HYPF PF07503.12 GAM40938.1 - 4.8 7.1 6.9 24 4.8 4.1 2.7 2 1 1 3 3 3 0 HypF finger LAT2 PF15703.5 GAM40939.1 - 0.011 15.6 0.2 0.014 15.3 0.2 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells family member 2 Zn_clus PF00172.18 GAM40940.1 - 0.13 12.4 7.4 0.24 11.6 7.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 GAM40940.1 - 1.6 8.9 5.7 5 7.3 5.7 2.0 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DEC-1_N PF04625.13 GAM40940.1 - 5.2 6.0 11.3 11 5.0 11.3 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DDE_3 PF13358.6 GAM40942.1 - 1.5e-33 115.6 0.0 2.9e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 GAM40942.1 - 1.4e-07 31.0 0.0 3.8e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix rve PF00665.26 GAM40942.1 - 0.00012 22.3 0.0 0.00028 21.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_1 PF03184.19 GAM40942.1 - 0.00034 20.3 0.0 0.00051 19.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 GAM40942.1 - 0.0032 17.7 0.0 0.0064 16.7 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 GAM40942.1 - 0.0049 17.5 0.2 0.031 14.9 0.0 2.3 3 0 0 3 3 3 1 Homeodomain-like domain DDE_Tnp_ISAZ013 PF07592.11 GAM40942.1 - 0.014 14.4 0.1 4.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain RRM_1 PF00076.22 GAM40944.1 - 1.1e-21 76.4 0.0 1.4e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM40944.1 - 0.0025 17.9 0.0 0.0036 17.4 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif GRP PF07172.11 GAM40944.1 - 0.41 11.4 26.5 0.64 10.7 26.5 1.4 1 0 0 1 1 1 0 Glycine rich protein family ChaC PF04752.12 GAM40945.1 - 3.1e-52 177.2 0.0 4e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein adh_short PF00106.25 GAM40946.1 - 5.2e-19 68.5 0.0 1.4e-17 63.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40946.1 - 1.2e-13 51.2 0.0 1.2e-11 44.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40946.1 - 1e-08 35.3 0.0 1.7e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM40946.1 - 0.0037 16.5 0.0 0.0058 15.8 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAM40946.1 - 0.0075 15.8 0.0 0.014 14.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family EF-hand_6 PF13405.6 GAM40947.1 - 8.8e-20 68.9 4.3 1.6e-06 27.6 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 GAM40947.1 - 2.7e-19 68.8 1.4 1e-08 34.9 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 GAM40947.1 - 1.1e-18 65.4 10.5 1.3e-06 27.5 0.2 4.4 4 1 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 GAM40947.1 - 3.8e-18 65.7 0.6 5.8e-07 29.9 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 GAM40947.1 - 1.3e-12 46.6 8.8 8.8e-06 25.0 0.5 3.9 3 1 0 3 3 3 3 EF hand Caleosin PF05042.13 GAM40947.1 - 0.091 12.7 1.3 11 6.0 0.1 3.0 2 1 0 3 3 3 0 Caleosin related protein DDT PF02791.17 GAM40947.1 - 0.11 12.8 0.0 1.1 9.7 0.0 2.2 1 1 1 2 2 2 0 DDT domain MFS_1 PF07690.16 GAM40948.1 - 5.2e-46 157.2 44.3 5.2e-46 157.2 44.3 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM40948.1 - 1.5e-21 76.5 12.8 1.5e-21 76.5 12.8 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM40948.1 - 1e-13 51.0 11.3 1e-13 51.0 11.3 3.3 3 0 0 3 3 3 1 Sugar (and other) transporter Aldedh PF00171.22 GAM40949.1 - 1.3e-70 238.2 10.5 2.9e-24 85.4 0.0 4.0 2 2 1 3 3 3 3 Aldehyde dehydrogenase family p450 PF00067.22 GAM40951.1 - 4.7e-70 236.6 0.0 6.1e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_8 PF13450.6 GAM40951.1 - 1.3e-05 25.4 0.0 3.6e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM40951.1 - 6e-05 22.4 0.0 0.00027 20.3 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM40951.1 - 9.7e-05 22.4 0.1 0.6 10.1 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 GAM40951.1 - 0.00061 19.1 0.0 0.0022 17.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 GAM40951.1 - 0.00094 18.9 1.2 0.32 10.5 0.6 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAM40951.1 - 0.063 12.6 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM40951.1 - 0.081 12.0 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 GAM40951.1 - 0.14 10.9 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans PF04082.18 GAM40952.1 - 1.3e-16 60.5 0.0 1.3e-16 60.5 0.0 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM40952.1 - 5.2e-09 36.1 9.2 8.4e-09 35.4 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KR PF08659.10 GAM40953.1 - 4.4e-50 170.1 0.1 1.7e-48 164.9 0.1 2.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 GAM40953.1 - 2e-07 30.8 0.1 7.6e-06 25.6 0.0 2.7 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM40953.1 - 3.1e-06 26.8 0.1 1.7e-05 24.3 0.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 GAM40953.1 - 9e-06 25.7 0.0 2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM40953.1 - 1.6e-05 24.7 0.1 3.7e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 GAM40953.1 - 0.0064 16.8 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ketoacyl-synt PF00109.26 GAM40954.1 - 2.6e-54 184.5 0.1 5.2e-45 154.0 0.0 2.9 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 GAM40954.1 - 3.1e-54 184.3 0.0 9e-53 179.4 0.0 2.2 1 1 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 GAM40954.1 - 5.5e-30 103.8 0.0 2e-29 102.0 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 GAM40954.1 - 1.7e-29 103.4 0.1 9.7e-21 74.6 0.0 2.3 1 1 1 2 2 2 2 Acyl transferase domain KAsynt_C_assoc PF16197.5 GAM40954.1 - 2.3e-15 57.0 0.0 6.2e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension DUF4350 PF14258.6 GAM40954.1 - 0.013 15.9 0.0 0.051 14.0 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) SRF-TF PF00319.18 GAM40955.1 - 3.5e-24 84.0 0.2 5.6e-24 83.4 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) F-box-like_2 PF13013.6 GAM40956.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain DUF1708 PF08101.11 GAM40957.1 - 6.7e-179 595.6 0.0 1.1e-178 594.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Muted PF14942.6 GAM40957.1 - 0.049 14.0 1.9 7.4 6.9 0.6 2.6 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF2406 PF10295.9 GAM40958.1 - 2.6e-27 95.3 1.5 7.4e-27 93.8 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) NSP2-B_epitope PF14757.6 GAM40958.1 - 0.054 13.2 3.9 0.098 12.3 3.9 1.4 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein adh_short PF00106.25 GAM40960.1 - 2.1e-44 151.4 0.0 2.8e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM40960.1 - 2.5e-27 96.0 0.0 3.2e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM40960.1 - 4.6e-08 33.2 0.0 6.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAM40960.1 - 1.9e-06 27.5 0.0 2.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 GAM40960.1 - 1.3e-05 24.8 0.1 2.6e-05 23.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM40960.1 - 0.024 14.5 0.1 0.035 14.0 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 GAM40960.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain G6PD_C PF02781.16 GAM40962.1 - 5.3e-113 377.0 0.0 9.1e-113 376.2 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 GAM40962.1 - 8.2e-61 205.7 0.1 1.5e-60 204.9 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MFS_2 PF13347.6 GAM40962.1 - 4.4e-13 48.6 8.7 4.4e-13 48.6 8.7 1.9 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 GAM40962.1 - 0.0011 18.0 3.6 0.0018 17.2 3.6 1.4 1 0 0 1 1 1 1 MFS_1 like family Ribosomal_L35Ae PF01247.18 GAM40963.1 - 3.3e-44 149.0 0.4 3.7e-44 148.8 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 GAM40963.1 - 0.0002 21.5 0.0 0.17 12.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 GAM40963.1 - 0.23 11.2 1.2 1.8 8.4 0.2 2.2 1 1 1 2 2 2 0 Putative transposon-encoded protein (DUF2080) VMA21 PF09446.10 GAM40964.1 - 3.8e-12 46.1 9.0 5.9e-12 45.5 9.0 1.3 1 0 0 1 1 1 1 VMA21-like domain CBS PF00571.28 GAM40965.1 - 7.8e-07 29.4 0.1 0.37 11.3 0.1 3.7 2 1 1 3 3 3 3 CBS domain Mito_carr PF00153.27 GAM40966.1 - 6.1e-47 157.5 5.6 2.8e-17 62.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein dUTPase PF00692.19 GAM40967.1 - 1.1e-14 54.2 0.0 1.6e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 GAM40967.1 - 0.0022 16.8 0.0 0.0045 15.8 0.0 1.5 1 1 1 2 2 2 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) AA_permease PF00324.21 GAM40968.1 - 6.8e-109 364.6 54.8 1.2e-106 357.2 54.8 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM40968.1 - 2.4e-20 72.8 55.2 5.7e-17 61.7 38.4 2.2 1 1 1 2 2 2 2 Amino acid permease HAD_2 PF13419.6 GAM40969.1 - 5.8e-06 26.5 0.0 1.1e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM40969.1 - 0.00033 21.0 0.0 0.0042 17.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L18A PF01775.17 GAM40969.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Fungal_trans_2 PF11951.8 GAM40970.1 - 3.4e-42 144.6 3.2 4e-42 144.4 3.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain 4HBT PF03061.22 GAM40971.1 - 3.4e-11 43.3 0.1 4.9e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily AMP-binding PF00501.28 GAM40972.1 - 3.7e-74 249.8 0.0 5.2e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ECH_1 PF00378.20 GAM40972.1 - 4.5e-45 153.9 0.3 6.7e-45 153.4 0.3 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM40972.1 - 7.1e-30 104.6 0.3 1.1e-29 104.0 0.3 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AMP-binding_C PF13193.6 GAM40972.1 - 0.00017 22.5 1.3 0.00031 21.6 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain KR PF08659.10 GAM40972.1 - 0.044 13.7 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 KR domain AAA_16 PF13191.6 GAM40974.1 - 4.1e-06 27.3 0.0 9.5e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 GAM40974.1 - 0.0005 20.1 0.0 0.00084 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAM40974.1 - 0.00071 20.1 0.0 0.0016 18.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Sigma54_activat PF00158.26 GAM40974.1 - 0.00077 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 GAM40974.1 - 0.00097 18.7 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 GAM40974.1 - 0.0013 19.2 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 GAM40974.1 - 0.0013 17.9 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 GAM40974.1 - 0.0021 18.3 0.3 0.012 15.9 0.3 2.0 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GAM40974.1 - 0.0026 17.7 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 GAM40974.1 - 0.0063 16.9 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 GAM40974.1 - 0.0092 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 GAM40974.1 - 0.013 15.0 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAM40974.1 - 0.015 15.7 0.4 0.28 11.5 0.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAM40974.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAM40974.1 - 0.022 13.8 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 GAM40974.1 - 0.03 14.0 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAM40974.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.16 GAM40974.1 - 0.053 13.0 0.8 0.33 10.4 0.1 2.0 1 1 1 2 2 2 0 PhoH-like protein DAP3 PF10236.9 GAM40974.1 - 0.062 12.5 0.1 0.29 10.3 0.0 1.8 1 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_5 PF07728.14 GAM40974.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAM40974.1 - 0.07 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Thymidylate_kin PF02223.17 GAM40974.1 - 0.084 12.5 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase SRP54 PF00448.22 GAM40974.1 - 0.092 12.4 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 GAM40974.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 GAM40974.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SWI2_SNF2 PF18766.1 GAM40974.1 - 0.13 11.9 0.3 0.31 10.7 0.2 1.5 1 1 1 2 2 2 0 SWI2/SNF2 ATPase TIP49 PF06068.13 GAM40974.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain MobB PF03205.14 GAM40974.1 - 0.16 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.14 GAM40974.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase NTPase_1 PF03266.15 GAM40974.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 GAM40974.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ResIII PF04851.15 GAM40974.1 - 0.18 11.8 0.5 0.63 10.0 0.5 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 GAM40974.1 - 0.19 12.2 0.3 0.41 11.1 0.1 1.6 2 0 0 2 2 1 0 AAA domain PEPCK_ATP PF01293.20 GAM40974.1 - 0.19 10.4 0.0 0.33 9.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 GAM40975.1 - 0.00071 20.0 0.0 0.002 18.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM40975.1 - 0.0023 18.2 0.2 0.044 14.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAM40975.1 - 0.0029 17.9 0.0 0.0062 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GAM40975.1 - 0.0042 17.0 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 GAM40975.1 - 0.0052 16.8 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 GAM40975.1 - 0.0062 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 KaiC ABC_tran PF00005.27 GAM40975.1 - 0.0068 16.9 0.0 0.03 14.9 0.0 2.1 1 1 0 1 1 1 1 ABC transporter zf-FCS PF06467.14 GAM40975.1 - 0.014 15.3 1.4 0.29 11.1 0.0 3.0 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif AAA_18 PF13238.6 GAM40975.1 - 0.026 15.1 0.0 0.091 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAM40975.1 - 0.035 13.8 0.1 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SSE PF00437.20 GAM40975.1 - 0.071 12.2 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein KTI12 PF08433.10 GAM40975.1 - 0.072 12.5 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_19 PF13245.6 GAM40975.1 - 0.077 13.3 0.0 5.6 7.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 GAM40975.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain 7TM_GPCR_Srab PF10292.9 GAM40975.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor DJ-1_PfpI PF01965.24 GAM40976.1 - 9.4e-13 48.3 0.0 5.6e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 GAM40976.1 - 1.5e-08 34.5 0.0 2.2e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like SNF2_N PF00176.23 GAM40977.1 - 6.3e-53 179.7 0.2 1.1e-52 178.9 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM40977.1 - 1.5e-18 67.1 0.1 1.1e-17 64.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM40977.1 - 1.3e-09 38.3 0.1 5.4e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAM40977.1 - 6.1e-05 22.3 0.1 0.00015 21.1 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 GAM40977.1 - 0.046 14.0 0.3 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif TBX PF12598.8 GAM40977.1 - 1.7 9.5 7.1 2.8 8.8 0.3 3.1 2 0 0 2 2 2 0 T-box transcription factor Cation_ATPase_C PF00689.21 GAM40978.1 - 1.9e-46 158.1 7.5 1.9e-46 158.1 7.5 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAM40978.1 - 9.3e-37 126.3 4.2 1.6e-36 125.6 0.0 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAM40978.1 - 3.9e-22 78.2 0.1 7e-22 77.3 0.1 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM40978.1 - 1.4e-19 71.2 0.0 3.2e-19 70.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM40978.1 - 4.1e-08 32.8 0.0 1.4e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM40978.1 - 5.6e-05 23.0 0.0 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1774 PF08611.10 GAM40978.1 - 0.084 13.2 4.9 0.24 11.7 0.1 2.8 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) Ferlin_C PF16165.5 GAM40978.1 - 0.46 10.4 2.9 0.39 10.7 0.3 2.2 2 0 0 2 2 2 0 Ferlin C-terminus Wzy_C PF04932.15 GAM40978.1 - 3.9 7.1 9.8 6.9 6.3 0.0 3.3 3 1 1 4 4 4 0 O-Antigen ligase SKG6 PF08693.10 GAM40980.1 - 4.7e-06 25.9 0.0 1.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PRR18 PF15671.5 GAM40980.1 - 9.7e-05 22.4 2.0 9.7e-05 22.4 2.0 1.6 1 1 1 2 2 2 1 Proline-rich protein family 18 Mid2 PF04478.12 GAM40980.1 - 0.0012 18.7 0.2 0.0021 17.9 0.2 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF4514 PF14986.6 GAM40980.1 - 0.096 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) Gly-zipper_YMGG PF13441.6 GAM40980.1 - 2.1 8.1 10.9 0.44 10.3 7.1 1.7 2 0 0 2 2 2 0 YMGG-like Gly-zipper Dus PF01207.17 GAM40981.1 - 1.5e-43 149.1 0.0 3.8e-43 147.7 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) PAN_1 PF00024.26 GAM40982.1 - 2e-11 43.7 11.7 0.0014 18.6 1.5 3.3 3 0 0 3 3 3 3 PAN domain TrbC PF04956.13 GAM40982.1 - 0.0027 17.9 0.0 0.0051 17.0 0.0 1.3 1 0 0 1 1 1 1 TrbC/VIRB2 family G6B PF15096.6 GAM40982.1 - 0.058 13.2 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 G6B family Phage_holin_2_4 PF16082.5 GAM40982.1 - 0.061 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like MANEC PF07502.14 GAM40982.1 - 0.42 10.9 10.9 0.31 11.3 0.3 3.5 3 1 0 3 3 3 0 MANEC domain Pyrophosphatase PF00719.19 GAM40983.1 - 9.6e-58 194.5 0.1 1.3e-57 194.1 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.9 GAM40984.1 - 1e-15 57.6 0.1 1.4e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.13 GAM40985.1 - 6.8e-18 64.4 5.9 3.6e-17 62.1 1.5 2.9 3 0 0 3 3 3 1 Sec20 DUF148 PF02520.17 GAM40985.1 - 0.02 15.0 0.8 0.58 10.3 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF148 ArsP_1 PF03773.13 GAM40985.1 - 0.033 13.4 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Predicted permease DUF3510 PF12022.8 GAM40985.1 - 0.055 13.8 2.5 0.066 13.6 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) CUT PF02376.15 GAM40985.1 - 0.96 9.7 4.2 9.4 6.5 4.2 2.5 1 1 0 1 1 1 0 CUT domain Rep_fac_C PF08542.11 GAM40986.1 - 3.2e-19 69.1 0.1 8.2e-19 67.8 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 GAM40986.1 - 2.5e-15 57.1 0.0 9.3e-15 55.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 GAM40986.1 - 1.8e-13 50.6 0.0 1.8e-12 47.3 0.0 2.5 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 GAM40986.1 - 6.6e-09 36.0 0.0 2.1e-08 34.3 0.0 1.9 2 1 0 2 2 1 1 Rad17 P-loop domain AAA_16 PF13191.6 GAM40986.1 - 8.6e-06 26.2 0.3 0.00098 19.5 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 GAM40986.1 - 1.7e-05 24.6 0.0 9.9e-05 22.1 0.0 2.2 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 GAM40986.1 - 6.4e-05 23.2 0.1 0.00025 21.3 0.1 2.1 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 GAM40986.1 - 7.2e-05 22.7 0.1 0.00024 21.0 0.0 1.9 1 1 1 2 2 2 1 AAA domain DUF2075 PF09848.9 GAM40986.1 - 8.9e-05 21.9 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 GAM40986.1 - 0.00012 22.3 0.0 0.00056 20.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAM40986.1 - 0.00024 20.5 0.0 0.016 14.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 GAM40986.1 - 0.00034 20.4 0.0 0.00082 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 GAM40986.1 - 0.00043 20.3 0.0 0.0013 18.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 GAM40986.1 - 0.00073 19.6 0.0 0.0024 17.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 GAM40986.1 - 0.0037 17.6 0.0 0.025 14.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 GAM40986.1 - 0.005 16.6 0.0 0.035 13.9 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase DUF815 PF05673.13 GAM40986.1 - 0.0059 15.8 0.0 0.0095 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 GAM40986.1 - 0.009 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 GAM40986.1 - 0.013 16.0 0.0 0.04 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAM40986.1 - 0.017 14.9 0.0 0.051 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 GAM40986.1 - 0.023 14.6 0.2 0.38 10.6 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 GAM40986.1 - 0.026 14.6 0.0 0.47 10.4 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 GAM40986.1 - 0.032 14.5 0.0 0.08 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 GAM40986.1 - 0.036 13.8 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_25 PF13481.6 GAM40986.1 - 0.061 12.9 0.7 0.96 9.0 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.6 GAM40986.1 - 0.14 12.6 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain SOGA PF11365.8 GAM40987.1 - 0.1 13.8 0.6 0.1 13.8 0.6 2.5 2 0 0 2 2 2 0 Protein SOGA Prefoldin_2 PF01920.20 GAM40987.1 - 0.11 12.5 1.7 0.34 10.9 1.7 1.8 1 0 0 1 1 1 0 Prefoldin subunit HET PF06985.11 GAM40988.1 - 1.1e-05 25.9 0.0 2.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EthD PF07110.11 GAM40991.1 - 0.036 15.2 0.0 0.081 14.1 0.0 1.5 1 1 0 1 1 1 0 EthD domain Gly-zipper_YMGG PF13441.6 GAM40993.1 - 0.0041 16.8 3.2 0.0079 15.9 3.2 1.4 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 GAM40993.1 - 0.0075 16.2 6.8 0.015 15.3 6.8 1.4 1 0 0 1 1 1 1 Glycine zipper Yip1 PF04893.17 GAM40993.1 - 0.015 15.0 0.1 0.022 14.5 0.1 1.2 1 0 0 1 1 1 0 Yip1 domain SKG6 PF08693.10 GAM40993.1 - 0.017 14.5 0.3 0.017 14.5 0.3 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Mucin PF01456.17 GAM40993.1 - 0.22 11.5 24.3 0.59 10.1 24.3 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein FeoB_associated PF12669.7 GAM40993.1 - 0.23 11.9 0.2 0.23 11.9 0.2 1.8 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Beta-APP PF03494.13 GAM40993.1 - 0.27 11.1 5.2 0.68 9.8 4.4 2.1 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) FAD_binding_2 PF00890.24 GAM40994.1 - 2e-126 422.5 3.4 2.5e-126 422.1 3.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 GAM40994.1 - 1.6e-44 151.0 1.0 2.4e-44 150.4 1.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 GAM40994.1 - 1.8e-06 27.4 0.2 0.0009 18.6 0.1 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM40994.1 - 0.00013 21.2 4.0 0.024 13.7 1.9 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.17 GAM40994.1 - 0.00027 20.3 0.2 0.05 12.8 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 GAM40994.1 - 0.0038 16.5 0.2 0.0075 15.6 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM40994.1 - 0.0088 15.7 1.0 0.026 14.1 1.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM40994.1 - 0.18 10.5 1.3 0.81 8.3 0.6 2.3 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 GAM40994.1 - 2.7 7.2 3.7 4.3 6.5 0.8 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AAA PF00004.29 GAM40995.1 - 5.9e-41 140.0 0.0 1.1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM40995.1 - 4.1e-06 26.5 0.1 1e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 GAM40995.1 - 7.1e-05 23.1 0.0 0.0059 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 GAM40995.1 - 0.00011 22.2 0.0 0.00043 20.3 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAM40995.1 - 0.00023 21.3 0.0 0.00069 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAM40995.1 - 0.00032 21.1 0.1 0.008 16.6 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 GAM40995.1 - 0.0019 17.4 0.0 0.0035 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 GAM40995.1 - 0.0082 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 GAM40995.1 - 0.021 15.1 0.1 0.063 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAM40995.1 - 0.029 13.9 0.0 0.097 12.2 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 GAM40995.1 - 0.049 13.8 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAM40995.1 - 0.059 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 GAM40995.1 - 0.082 12.6 0.1 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 GAM40995.1 - 0.084 12.7 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAM40995.1 - 0.089 12.5 0.1 0.24 11.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain DUF4164 PF13747.6 GAM40995.1 - 0.095 13.0 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) AAA_14 PF13173.6 GAM40995.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAM40995.1 - 0.15 12.6 0.0 0.48 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 GAM40995.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cpn60_TCP1 PF00118.24 GAM40996.1 - 3.9e-147 490.8 13.9 5e-147 490.5 13.9 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DPPIV_N PF00930.21 GAM40996.1 - 7.5e-111 370.3 0.4 1.2e-110 369.6 0.4 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 GAM40996.1 - 2.6e-57 193.7 4.8 2.6e-57 193.7 4.8 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GAM40996.1 - 3.1e-06 27.0 4.9 6e-05 22.8 2.3 2.4 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 GAM40996.1 - 9.6e-05 22.1 0.7 0.00025 20.8 0.7 1.6 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 GAM40996.1 - 0.00018 21.3 0.5 0.00038 20.2 0.2 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 GAM40996.1 - 0.00024 20.8 0.0 0.003 17.2 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S10 PF00450.22 GAM40996.1 - 0.0048 16.3 0.1 0.55 9.6 0.0 2.3 2 0 0 2 2 2 1 Serine carboxypeptidase Abhydrolase_2 PF02230.16 GAM40996.1 - 0.021 14.6 0.2 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase COesterase PF00135.28 GAM40996.1 - 0.024 13.5 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Questin_oxidase PF14027.6 GAM40997.1 - 1.8e-65 221.7 0.1 2.3e-65 221.4 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like HECT_2 PF09814.9 GAM40998.1 - 3.8e-107 358.4 0.0 4.3e-107 358.2 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 GAM40998.1 - 0.16 12.2 0.6 7.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TauD PF02668.16 GAM41000.1 - 3e-61 207.6 2.2 3.7e-61 207.3 2.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 GAM41001.1 - 1.3e-15 57.2 19.0 1.4e-15 57.1 8.0 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily F-box-like PF12937.7 GAM41002.1 - 3.5e-05 23.6 1.6 5.5e-05 23.0 0.4 2.1 2 0 0 2 2 2 1 F-box-like Trypan_PARP PF05887.11 GAM41004.1 - 0.00067 19.7 6.1 0.00067 19.7 6.1 1.4 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) DDHD PF02862.17 GAM41004.1 - 0.0073 16.5 2.2 0.0078 16.4 2.2 1.1 1 0 0 1 1 1 1 DDHD domain Merozoite_SPAM PF07133.11 GAM41004.1 - 0.062 13.3 19.2 0.077 13.0 19.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Paf1 PF03985.13 GAM41004.1 - 0.065 12.2 12.2 0.076 12.0 12.2 1.1 1 0 0 1 1 1 0 Paf1 DUF515 PF04415.12 GAM41004.1 - 0.24 9.7 16.7 0.3 9.4 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF5523 PF17661.1 GAM41004.1 - 0.25 11.0 10.3 0.31 10.7 10.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF4820 PF16091.5 GAM41004.1 - 0.28 10.5 10.0 0.35 10.2 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Nop14 PF04147.12 GAM41004.1 - 0.64 8.2 17.7 0.8 7.8 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family INO80_Ies4 PF08193.11 GAM41004.1 - 0.65 9.9 6.3 1.1 9.2 6.3 1.3 1 0 0 1 1 1 0 INO80 complex subunit Ies4 Macoilin PF09726.9 GAM41004.1 - 0.83 8.1 8.9 0.93 8.0 8.9 1.0 1 0 0 1 1 1 0 Macoilin family DUF913 PF06025.12 GAM41004.1 - 1.7 7.5 7.9 2.2 7.2 7.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NESP55 PF06390.12 GAM41004.1 - 1.7 8.1 25.3 5.7 6.5 25.3 1.9 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) RP-C_C PF11800.8 GAM41004.1 - 2 8.5 5.8 3.1 7.8 5.8 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Nop25 PF09805.9 GAM41004.1 - 2.9 8.4 10.6 4.1 7.9 10.6 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) MAP17 PF15807.5 GAM41004.1 - 3.3 8.0 5.8 4.8 7.4 5.8 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SDA1 PF05285.12 GAM41004.1 - 3.7 6.9 18.9 4.7 6.5 18.9 1.2 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 GAM41004.1 - 4.9 6.5 17.6 6.3 6.1 17.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 GAM41004.1 - 7.6 4.7 16.9 9.3 4.4 16.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GAM41004.1 - 8 4.4 19.4 9.5 4.2 19.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Hid1 PF12722.7 GAM41004.1 - 9 4.3 8.0 9.8 4.2 8.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GST_C_2 PF13410.6 GAM41005.1 - 8.3e-06 25.7 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM41005.1 - 2.3e-05 24.5 0.0 4.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM41005.1 - 2.6e-05 24.5 0.0 0.00014 22.2 0.1 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM41005.1 - 0.013 15.7 0.0 0.036 14.3 0.0 1.7 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Ribosomal_L37 PF08561.10 GAM41006.1 - 3.4e-44 150.2 0.3 4.9e-44 149.7 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 adh_short PF00106.25 GAM41007.1 - 4.1e-21 75.3 0.6 1.2e-17 64.0 0.5 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM41007.1 - 1.6e-10 40.9 1.3 8e-08 32.1 0.3 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM41007.1 - 0.00024 21.0 0.1 0.00058 19.8 0.1 1.5 1 0 0 1 1 1 1 KR domain EthD PF07110.11 GAM41007.1 - 0.11 13.6 0.0 0.37 12.0 0.0 1.9 2 0 0 2 2 2 0 EthD domain DUF1776 PF08643.10 GAM41007.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) AA_permease_2 PF13520.6 GAM41008.1 - 3.6e-48 164.5 49.1 5e-48 164.0 49.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM41008.1 - 3.6e-19 68.7 42.9 4.9e-19 68.3 42.9 1.0 1 0 0 1 1 1 1 Amino acid permease AAA PF00004.29 GAM41009.1 - 8.1e-51 171.9 0.0 2.7e-43 147.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM41009.1 - 1.3e-08 34.5 8.1 9.5e-05 22.1 0.2 3.0 3 0 0 3 3 3 2 AAA+ lid domain RuvB_N PF05496.12 GAM41009.1 - 8.7e-05 22.3 0.0 0.00042 20.1 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAM41009.1 - 9e-05 22.9 0.0 0.023 15.1 0.0 3.2 3 0 0 3 3 2 1 AAA ATPase domain Parvo_NS1 PF01057.17 GAM41009.1 - 0.00056 19.1 0.0 0.00097 18.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 GAM41009.1 - 0.0009 19.4 0.0 0.45 10.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAM41009.1 - 0.001 19.4 0.2 0.046 14.0 0.0 3.3 3 1 1 4 4 3 1 AAA domain RNA_helicase PF00910.22 GAM41009.1 - 0.0021 18.4 0.0 0.016 15.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.14 GAM41009.1 - 0.0032 17.6 0.0 0.0085 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 GAM41009.1 - 0.004 16.8 0.1 0.043 13.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 GAM41009.1 - 0.0064 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 GAM41009.1 - 0.009 15.8 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 GAM41009.1 - 0.015 15.9 0.0 0.12 12.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 GAM41009.1 - 0.018 14.4 0.1 0.051 12.9 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 GAM41009.1 - 0.031 13.6 0.0 0.083 12.2 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 GAM41009.1 - 0.035 14.1 0.0 0.13 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 GAM41009.1 - 0.036 14.1 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 GAM41009.1 - 0.042 13.4 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 GAM41009.1 - 0.063 13.3 0.0 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAM41009.1 - 0.07 13.4 0.0 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 GAM41009.1 - 0.098 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 GAM41009.1 - 0.11 12.2 0.2 0.97 9.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAM41009.1 - 0.13 11.5 0.0 3.1 6.9 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain MFS_1 PF07690.16 GAM41010.1 - 6.2e-32 110.9 32.4 1.1e-31 110.1 31.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM41010.1 - 1e-16 60.5 17.5 7.4e-15 54.4 17.5 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM41010.1 - 1.6e-13 50.3 2.2 1.6e-13 50.3 2.2 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 GAM41010.1 - 1 7.6 12.5 0.046 12.0 3.3 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4519 PF15012.6 GAM41010.1 - 1.9 8.7 4.2 1.1 9.5 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) zf-C2H2 PF00096.26 GAM41011.1 - 0.001 19.4 21.7 0.0043 17.4 7.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 GAM41011.1 - 0.0013 18.5 0.2 0.0013 18.5 0.2 2.9 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 GAM41011.1 - 0.018 15.8 6.2 0.018 15.8 6.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAM41011.1 - 0.43 10.9 9.2 0.97 9.8 6.5 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 GAM41011.1 - 1.2 9.2 6.4 3.3 7.8 0.5 2.8 2 0 0 2 2 2 0 BED zinc finger AA_permease_2 PF13520.6 GAM41012.1 - 2.9e-54 184.5 41.1 3.6e-54 184.2 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM41012.1 - 1.5e-20 73.3 32.2 2e-20 72.8 32.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.8 GAM41012.1 - 0.073 13.2 0.0 0.34 11.1 0.0 2.2 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 Cu_amine_oxid PF01179.20 GAM41013.1 - 4.1e-150 500.3 0.0 5e-150 500.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 GAM41013.1 - 2.9e-19 69.4 0.0 1.2e-18 67.4 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 GAM41013.1 - 3.4e-08 33.6 0.0 5.8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF4105 PF13387.6 GAM41013.1 - 0.13 11.8 0.5 13 5.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4105) Aldedh PF00171.22 GAM41014.1 - 2.3e-21 75.9 0.0 2.5e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CM_1 PF07736.11 GAM41014.1 - 0.019 15.3 0.0 0.027 14.9 0.0 1.2 1 0 0 1 1 1 0 Chorismate mutase type I Aldedh PF00171.22 GAM41015.1 - 6.2e-137 456.9 0.1 6.9e-137 456.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAM41015.1 - 0.035 13.6 0.0 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF3818 PF12825.7 GAM41016.1 - 4.8e-133 443.4 5.5 4.8e-133 443.4 5.5 1.7 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) MFS_1 PF07690.16 GAM41016.1 - 1.1e-44 152.8 41.0 9.8e-44 149.7 41.1 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily PXB PF12828.7 GAM41016.1 - 1e-38 132.3 0.7 1.8e-38 131.5 0.7 1.4 1 0 0 1 1 1 1 PX-associated Sugar_tr PF00083.24 GAM41016.1 - 3.8e-12 45.8 26.5 4.7e-11 42.2 16.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter PX PF00787.24 GAM41016.1 - 2e-10 40.6 0.2 9.5e-10 38.5 0.0 2.3 2 0 0 2 2 2 1 PX domain zf-GRF PF06839.12 GAM41017.1 - 0.0037 17.3 1.2 0.0067 16.5 1.2 1.4 1 0 0 1 1 1 1 GRF zinc finger TMF_DNA_bd PF12329.8 GAM41017.1 - 0.07 13.1 2.0 0.13 12.2 2.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 GAM41017.1 - 0.07 13.5 0.4 0.15 12.5 0.4 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain Tho2 PF11262.8 GAM41017.1 - 0.14 11.3 0.1 0.2 10.8 0.1 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Met_10 PF02475.16 GAM41018.1 - 7.1e-68 228.3 0.0 1.3e-67 227.4 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein TRM PF02005.16 GAM41018.1 - 0.021 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase RNA_pol_Rpb4 PF03874.16 GAM41019.1 - 4.5e-26 91.6 3.5 7e-26 91.0 3.5 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Cut8 PF08559.10 GAM41019.1 - 0.00052 19.7 0.9 0.0006 19.5 0.9 1.2 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein TROVE PF05731.11 GAM41019.1 - 0.062 12.3 0.1 0.069 12.2 0.1 1.1 1 0 0 1 1 1 0 TROVE domain FAD_binding_3 PF01494.19 GAM41020.1 - 9.1e-12 44.9 0.2 2.1e-07 30.5 0.0 2.2 1 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAM41020.1 - 0.099 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3328 PF11807.8 GAM41021.1 - 3.3e-46 157.8 1.5 4.3e-46 157.4 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ribosomal_S8e PF01201.22 GAM41022.1 - 2.5e-44 150.8 2.4 3.7e-44 150.2 2.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e PA26 PF04636.13 GAM41022.1 - 0.14 11.1 2.9 0.18 10.7 2.9 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CPP1-like PF11833.8 GAM41022.1 - 0.35 10.5 1.8 0.61 9.7 1.8 1.4 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Fungal_trans PF04082.18 GAM41023.1 - 1e-17 64.1 0.0 1.9e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM41023.1 - 0.0018 18.4 5.0 0.003 17.6 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5639 PF18690.1 GAM41023.1 - 0.33 11.2 1.7 0.58 10.4 0.6 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5639) Amidase PF01425.21 GAM41024.1 - 1.2e-21 77.2 0.4 2.7e-20 72.7 0.1 2.1 2 0 0 2 2 2 2 Amidase Sugar_tr PF00083.24 GAM41025.1 - 3.4e-102 342.7 24.8 4e-102 342.4 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM41025.1 - 3.5e-24 85.4 25.5 3.5e-24 85.4 25.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily BNR_2 PF13088.6 GAM41026.1 - 1.4e-69 234.5 0.0 1.6e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 GAM41026.1 - 1.7e-05 24.1 12.5 0.22 11.7 1.1 4.9 4 0 0 4 4 4 3 BNR/Asp-box repeat BNR_4 PF15892.5 GAM41026.1 - 0.00035 20.0 0.0 2.4 7.5 0.0 3.2 2 1 0 2 2 2 2 BNR repeat-containing family member Sortilin-Vps10 PF15902.5 GAM41026.1 - 0.011 14.5 0.4 1.7 7.4 0.1 2.5 3 0 0 3 3 3 0 Sortilin, neurotensin receptor 3, Aldo_ket_red PF00248.21 GAM41027.1 - 8.9e-66 222.1 0.0 1.1e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.28 GAM41028.1 - 2.5e-46 158.2 0.0 5.6e-46 157.0 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 GAM41028.1 - 8.4e-28 98.0 0.2 2.1e-27 96.7 0.2 1.7 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 GAM41028.1 - 4.4e-08 33.4 0.5 1.1e-07 32.1 0.1 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_1 PF00561.20 GAM41028.1 - 0.0019 17.9 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM41028.1 - 0.0084 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM41028.1 - 0.0096 16.5 0.1 0.018 15.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PEP-CTERM PF07589.11 GAM41029.1 - 0.093 12.8 1.8 0.17 12.0 1.8 1.5 1 0 0 1 1 1 0 PEP-CTERM motif Methyltransf_2 PF00891.18 GAM41030.1 - 2.7e-28 98.7 0.0 3.9e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 GAM41030.1 - 0.052 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 GAM41030.1 - 0.099 13.4 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain LETM1 PF07766.13 GAM41031.1 - 2.8e-104 348.2 0.2 2.8e-104 348.2 0.2 1.4 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 GAM41031.1 - 2.3e-05 24.0 0.1 0.0029 17.3 0.0 3.3 3 0 0 3 3 3 1 SAP domain BPL_N PF09825.9 GAM41031.1 - 2.2 7.3 13.3 1.7 7.6 0.1 2.5 2 1 0 2 2 2 0 Biotin-protein ligase, N terminal DUF2841 PF11001.8 GAM41032.1 - 5.4e-51 171.8 0.0 9.6e-51 171.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF2838 PF10998.8 GAM41032.1 - 2.5e-42 143.6 8.5 2.5e-42 143.6 8.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) SMC_N PF02463.19 GAM41033.1 - 3e-58 196.9 2.5 8.2e-57 192.2 2.5 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAM41033.1 - 4.8e-31 107.5 0.0 2e-30 105.5 0.0 2.2 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GAM41033.1 - 1.5e-10 41.4 0.5 1.4e-05 25.1 0.1 4.2 5 0 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAM41033.1 - 9.2e-09 36.1 25.1 9.2e-09 36.1 25.1 6.6 4 1 1 5 5 4 2 AAA domain AAA_29 PF13555.6 GAM41033.1 - 3.2e-08 33.2 0.0 7.6e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 GAM41033.1 - 0.00037 20.3 17.8 0.00037 20.3 17.8 4.9 3 1 1 4 4 3 1 AAA ATPase domain FPP PF05911.11 GAM41033.1 - 0.00078 17.8 2.6 0.00078 17.8 2.6 4.1 4 0 0 4 4 4 2 Filament-like plant protein, long coiled-coil SbcCD_C PF13558.6 GAM41033.1 - 0.0028 17.9 0.0 0.018 15.2 0.0 2.5 2 0 0 2 2 1 1 Putative exonuclease SbcCD, C subunit MscS_porin PF12795.7 GAM41033.1 - 0.0075 15.8 3.7 0.0075 15.8 3.7 7.0 5 1 0 6 6 6 1 Mechanosensitive ion channel porin domain GFD1 PF17331.2 GAM41033.1 - 0.012 15.8 4.7 0.047 13.9 4.7 2.1 1 0 0 1 1 1 0 GFD1 mRNA transport factor ATG16 PF08614.11 GAM41033.1 - 0.012 15.8 7.5 0.012 15.8 7.5 6.4 5 1 0 6 6 5 0 Autophagy protein 16 (ATG16) TMP_2 PF06791.13 GAM41033.1 - 0.22 11.1 2.8 0.16 11.7 0.3 2.1 2 0 0 2 2 2 0 Prophage tail length tape measure protein AAA_22 PF13401.6 GAM41033.1 - 0.44 10.8 5.6 10 6.4 0.0 4.7 4 1 0 4 4 4 0 AAA domain ABC_tran PF00005.27 GAM41033.1 - 0.93 10.0 0.0 0.93 10.0 0.0 6.5 4 3 1 5 5 4 0 ABC transporter DUF2939 PF11159.8 GAM41033.1 - 1.5 9.3 3.8 13 6.3 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) Filament PF00038.21 GAM41033.1 - 3.9 7.0 100.3 0.047 13.3 4.6 7.0 4 1 2 6 6 6 0 Intermediate filament protein CcmD PF04995.14 GAM41034.1 - 0.0032 17.5 0.1 0.0077 16.3 0.1 1.6 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) E3_binding PF02817.17 GAM41035.1 - 1.3e-09 38.2 0.1 3.6e-09 36.8 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain WD40 PF00400.32 GAM41036.1 - 1.2e-25 89.2 12.2 2.5e-05 24.9 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM41036.1 - 7.5e-15 55.0 5.3 0.00022 21.5 0.3 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM41036.1 - 4.8e-08 33.1 0.1 0.055 13.3 0.0 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAM41036.1 - 0.02 13.9 0.0 0.064 12.2 0.0 1.8 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 GAM41036.1 - 0.033 13.1 1.5 1 8.2 0.1 2.4 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 GAM41036.1 - 0.18 10.4 0.7 0.34 9.5 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Peptidase_M18 PF02127.15 GAM41037.1 - 6.6e-170 565.6 0.0 7.5e-170 565.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Ribosomal_L21p PF00829.21 GAM41038.1 - 3.1e-09 37.0 0.0 5.4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF1180 PF06679.12 GAM41038.1 - 0.27 11.6 3.1 0.47 10.9 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NUDIX PF00293.28 GAM41039.1 - 3.1e-08 33.7 0.3 1.7e-07 31.4 0.0 2.1 1 1 0 2 2 2 1 NUDIX domain Glyco_hydro_38N PF01074.22 GAM41043.1 - 2.7e-88 296.1 0.9 6e-88 294.9 0.9 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAM41043.1 - 6.8e-46 157.0 0.1 1.6e-44 152.6 0.1 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GAM41043.1 - 1.2e-26 92.7 0.0 2.8e-26 91.5 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 GAM41043.1 - 5.8e-13 48.7 0.0 1.9e-12 47.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain NuA4 PF09340.10 GAM41044.1 - 2.2e-27 94.7 0.2 6e-27 93.3 0.2 1.8 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Ctr PF04145.15 GAM41045.1 - 2.9e-32 112.3 1.4 3.5e-32 112.1 1.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family T2SSF PF00482.23 GAM41045.1 - 0.057 13.4 0.1 0.081 12.9 0.1 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F F-box PF00646.33 GAM41046.1 - 6.3e-08 32.3 0.0 1.5e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAM41046.1 - 2.2e-07 30.6 0.5 4.7e-07 29.6 0.5 1.6 1 0 0 1 1 1 1 F-box-like Cupin_8 PF13621.6 GAM41046.1 - 7.8e-07 29.1 0.1 0.041 13.6 0.0 2.2 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 GAM41046.1 - 0.0012 19.3 0.0 0.0023 18.3 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase F-box_4 PF15966.5 GAM41046.1 - 0.03 14.2 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 F-box DUF3545 PF12065.8 GAM41046.1 - 0.081 12.9 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) DEAD PF00270.29 GAM41047.1 - 1.2e-44 152.2 1.1 2.1e-44 151.4 1.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM41047.1 - 3.6e-32 111.0 0.2 5e-31 107.3 0.1 2.5 2 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM41047.1 - 8.3e-07 29.2 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 GAM41047.1 - 0.00012 21.9 0.2 0.00022 21.0 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM41047.1 - 0.00047 20.5 0.2 0.0032 17.8 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAM41047.1 - 0.0081 16.4 1.2 0.054 13.8 1.2 2.3 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 GAM41047.1 - 0.0098 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit fragilysinNterm PF16376.5 GAM41047.1 - 0.075 12.8 0.1 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain of fragilysin Flavi_DEAD PF07652.14 GAM41047.1 - 0.081 12.9 0.0 0.81 9.7 0.0 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain DUF1664 PF07889.12 GAM41048.1 - 0.00039 20.4 4.7 0.0093 16.0 1.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) IFT57 PF10498.9 GAM41048.1 - 0.0053 15.8 3.7 0.0077 15.2 3.7 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Retrotrans_gag PF03732.17 GAM41048.1 - 0.097 13.0 0.1 0.51 10.7 0.0 2.2 2 1 0 2 2 2 0 Retrotransposon gag protein Cnn_1N PF07989.11 GAM41048.1 - 0.19 11.9 2.1 5.9 7.1 0.1 2.7 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 YopH_N PF09013.10 GAM41048.1 - 0.19 12.0 2.7 4.1 7.7 0.5 2.5 1 1 1 2 2 2 0 YopH, N-terminal TMCO5 PF14992.6 GAM41048.1 - 0.25 10.9 6.7 0.82 9.2 6.3 1.9 1 1 0 1 1 1 0 TMCO5 family Fez1 PF06818.15 GAM41048.1 - 0.27 11.7 3.0 0.55 10.7 3.0 1.6 1 1 0 1 1 1 0 Fez1 YabA PF06156.13 GAM41048.1 - 0.38 11.4 4.1 1.6 9.4 0.6 2.7 1 1 1 2 2 2 0 Initiation control protein YabA ADIP PF11559.8 GAM41048.1 - 0.59 10.2 8.2 0.078 13.1 1.6 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CLZ PF16526.5 GAM41048.1 - 1.1 9.7 4.1 1.4 9.3 0.4 2.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels JIP_LZII PF16471.5 GAM41048.1 - 4.9 7.4 6.2 2.5 8.3 0.7 2.9 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II FAA_hydrolase PF01557.18 GAM41049.1 - 1.9e-53 181.3 0.0 2.3e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Pkinase PF00069.25 GAM41050.1 - 4.6e-47 160.6 0.0 7.6e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM41050.1 - 2.1e-17 63.3 0.0 3.2e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 GAM41050.1 - 0.0032 17.1 0.2 0.006 16.2 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 GAM41050.1 - 0.0081 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM41050.1 - 0.0091 14.8 0.3 0.042 12.6 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAM41050.1 - 0.031 13.6 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 GAM41050.1 - 0.08 12.9 0.0 0.44 10.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family VbhA PF18495.1 GAM41051.1 - 0.018 14.9 3.6 0.53 10.2 0.1 3.4 3 0 0 3 3 3 0 Antitoxin VbhA PWI PF01480.17 GAM41052.1 - 8.5e-30 102.9 0.1 1.5e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 PWI domain Fmp27_WPPW PF10359.9 GAM41052.1 - 0.058 12.2 0.9 0.082 11.7 0.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2058 PF09831.9 GAM41052.1 - 2.3 8.3 7.3 4.1 7.5 6.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) adh_short PF00106.25 GAM41054.1 - 4e-35 121.0 0.0 5.3e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM41054.1 - 5.6e-20 71.9 0.0 6.9e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM41054.1 - 9.9e-07 28.8 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 GAM41054.1 - 0.0006 19.9 0.0 0.00097 19.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 GAM41054.1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 GAM41054.1 - 0.0035 16.9 0.0 0.014 14.8 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAM41054.1 - 0.006 16.8 0.1 0.01 16.1 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 GAM41054.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_2 PF03446.15 GAM41054.1 - 0.16 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Hydrolase_6 PF13344.6 GAM41055.1 - 2.1e-28 98.4 0.0 3.9e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM41055.1 - 8.5e-14 51.4 0.0 1.6e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAM41055.1 - 1e-11 45.5 0.0 6.1e-05 23.4 0.0 3.0 1 1 2 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAM41055.1 - 5.4e-05 23.4 0.1 0.052 13.6 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase FR47 PF08445.10 GAM41056.1 - 1.7e-05 24.7 0.0 4.9e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 GAM41056.1 - 0.01 16.1 0.0 0.03 14.6 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM41056.1 - 0.011 16.1 0.0 0.077 13.4 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RRG8 PF17068.5 GAM41056.1 - 0.044 13.2 0.0 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Required for respiratory growth protein 8 mitochondrial FeoC PF09012.10 GAM41056.1 - 0.096 12.8 0.0 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 FeoC like transcriptional regulator CLP_protease PF00574.23 GAM41057.1 - 3.2e-75 252.0 0.0 4.2e-75 251.6 0.0 1.1 1 0 0 1 1 1 1 Clp protease Tugs PF17840.1 GAM41057.1 - 0.085 13.1 1.1 0.2 11.9 1.1 1.6 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain RRM_1 PF00076.22 GAM41058.1 - 1e-42 143.8 0.0 2.7e-20 72.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM41058.1 - 0.0004 20.4 0.0 0.13 12.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif CpcD PF01383.21 GAM41059.1 - 0.17 12.2 0.5 0.46 10.8 0.5 1.8 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain ABC2_membrane_5 PF13346.6 GAM41059.1 - 0.18 11.3 0.0 0.27 10.8 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein VP4_2 PF08935.10 GAM41059.1 - 2.3 8.8 7.3 7.7 7.2 0.3 3.2 3 1 0 3 3 3 0 Viral protein VP4 subunit MFS_1 PF07690.16 GAM41060.1 - 3.2e-34 118.4 57.8 6.7e-25 87.7 24.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4786 PF16027.5 GAM41060.1 - 0.2 12.2 0.1 0.4 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4786) Aa_trans PF01490.18 GAM41061.1 - 1.7e-15 56.7 28.3 1.7e-14 53.4 28.3 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein FR47 PF08445.10 GAM41062.1 - 0.0008 19.3 0.0 0.0083 16.1 0.0 2.2 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 GAM41062.1 - 0.0059 16.8 0.0 0.025 14.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 GAM41062.1 - 0.007 17.0 0.2 0.042 14.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM41062.1 - 0.081 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NACHT PF05729.12 GAM41063.1 - 6.9e-18 65.1 0.0 7.9e-12 45.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain NB-ARC PF00931.22 GAM41063.1 - 7.3e-14 51.6 0.0 1.4e-10 40.8 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_16 PF13191.6 GAM41063.1 - 3e-09 37.5 0.1 5e-05 23.7 0.0 3.6 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 GAM41063.1 - 5.2e-09 36.5 0.1 0.0016 18.7 0.0 3.9 3 2 1 4 4 4 2 AAA domain PNP_UDP_1 PF01048.20 GAM41063.1 - 1.4e-08 34.3 0.0 3.7e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 GAM41063.1 - 2.3e-07 31.3 0.1 0.00011 22.7 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) AAA PF00004.29 GAM41063.1 - 2.8e-06 27.8 0.0 0.042 14.3 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAM41063.1 - 7.3e-06 25.8 0.0 0.097 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAM41063.1 - 7.4e-06 26.5 0.0 0.098 13.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GAM41063.1 - 1.8e-05 25.0 0.0 0.0088 16.4 0.0 3.1 3 0 0 3 3 2 1 RNA helicase AAA_25 PF13481.6 GAM41063.1 - 3.8e-05 23.3 0.0 0.031 13.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 GAM41063.1 - 0.00013 21.7 0.0 0.55 9.9 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 GAM41063.1 - 0.00045 20.2 0.0 0.61 10.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.17 GAM41063.1 - 0.0022 17.1 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 GAM41063.1 - 0.0043 16.3 0.0 1.2 8.3 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.12 GAM41063.1 - 0.0045 16.7 0.0 0.76 9.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAM41063.1 - 0.0056 16.8 0.0 5.9 7.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 GAM41063.1 - 0.0059 16.5 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 1 NTPase Ank_3 PF13606.6 GAM41063.1 - 0.0081 16.6 0.0 1.6 9.5 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat KTI12 PF08433.10 GAM41063.1 - 0.013 14.9 0.0 4.3 6.7 0.0 2.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 TIP49 PF06068.13 GAM41063.1 - 0.018 14.3 0.0 0.35 10.0 0.0 2.3 2 0 0 2 2 2 0 TIP49 P-loop domain KAP_NTPase PF07693.14 GAM41063.1 - 0.021 14.1 0.0 2 7.6 0.0 2.4 1 1 0 2 2 2 0 KAP family P-loop domain ATPase PF06745.13 GAM41063.1 - 0.037 13.4 0.0 4.8 6.4 0.0 2.6 2 0 0 2 2 2 0 KaiC MMR_HSR1 PF01926.23 GAM41063.1 - 0.051 13.7 0.0 34 4.6 0.0 3.4 3 1 0 3 3 3 0 50S ribosome-binding GTPase AAA_28 PF13521.6 GAM41063.1 - 0.051 13.8 0.1 14 5.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 GAM41063.1 - 0.058 12.8 0.2 1.7 8.0 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.20 GAM41063.1 - 0.088 12.7 0.0 0.95 9.3 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase Rad17 PF03215.15 GAM41063.1 - 0.11 12.5 0.0 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain Ank_4 PF13637.6 GAM41063.1 - 0.11 13.1 0.1 16 6.2 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) AA_permease_2 PF13520.6 GAM41064.1 - 6.5e-36 124.1 28.7 1.1e-35 123.3 28.7 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM41064.1 - 3.3e-18 65.5 23.2 4.5e-18 65.1 23.2 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_6 PF12697.7 GAM41064.1 - 2.8e-07 31.4 0.2 6e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM41064.1 - 2.6e-05 23.6 0.1 9.7e-05 21.7 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM41064.1 - 0.0014 18.3 0.0 0.032 13.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM41064.1 - 0.018 14.5 0.0 0.37 10.2 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family PAF-AH_p_II PF03403.13 GAM41064.1 - 0.28 9.7 2.0 0.4 9.1 0.1 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Lyase_1 PF00206.20 GAM41068.1 - 3.7e-86 289.4 0.0 5.4e-86 288.8 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 GAM41068.1 - 1.9e-23 83.0 0.0 7.2e-23 81.1 0.0 2.0 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal ADH_zinc_N PF00107.26 GAM41069.1 - 3.4e-10 40.0 0.1 3.8e-09 36.6 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM41069.1 - 1.8e-07 31.0 0.0 0.0012 18.7 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM41069.1 - 3.3e-06 28.2 0.0 1.6e-05 26.0 0.0 1.9 1 1 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAM41069.1 - 0.0013 18.1 0.0 0.017 14.5 0.0 2.4 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N_2 PF16884.5 GAM41069.1 - 0.0024 17.7 0.0 0.0073 16.2 0.0 1.8 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase Glu_dehyd_C PF16912.5 GAM41069.1 - 0.0086 15.6 0.1 0.019 14.4 0.1 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus RmlD_sub_bind PF04321.17 GAM41069.1 - 0.013 14.6 0.0 0.035 13.2 0.0 1.7 1 1 1 2 2 2 0 RmlD substrate binding domain AsnA PF03590.15 GAM41070.1 - 0.02 14.6 0.1 0.043 13.6 0.0 1.5 2 0 0 2 2 2 0 Aspartate-ammonia ligase Methyltransf_12 PF08242.12 GAM41070.1 - 0.035 14.8 0.1 0.081 13.7 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAM41070.1 - 0.036 14.8 0.1 0.24 12.1 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain SBF PF01758.16 GAM41072.1 - 5.2e-51 173.1 3.7 5.2e-51 173.1 3.7 2.1 2 2 1 3 3 3 1 Sodium Bile acid symporter family LMWPc PF01451.21 GAM41073.1 - 2.6e-23 83.0 0.0 3.4e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase FMN_red PF03358.15 GAM41074.1 - 5.4e-23 81.4 0.0 7.4e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Methyltransf_31 PF13847.6 GAM41075.1 - 1.5e-31 109.2 0.0 2.4e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM41075.1 - 2.8e-21 76.0 0.0 6.1e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM41075.1 - 4.4e-20 72.1 0.0 1.7e-19 70.2 0.0 2.0 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM41075.1 - 3.7e-15 55.9 0.0 7e-15 55.0 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAM41075.1 - 5e-10 40.0 0.0 8.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM41075.1 - 3.8e-09 36.6 0.0 7.8e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAM41075.1 - 1e-08 35.0 0.2 1.7e-08 34.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 GAM41075.1 - 1.8e-07 31.1 0.2 4.6e-07 29.8 0.1 1.7 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 GAM41075.1 - 2e-05 24.2 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 GAM41075.1 - 0.00014 21.2 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 GAM41075.1 - 0.00018 21.3 0.0 0.00051 19.8 0.0 1.7 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.15 GAM41075.1 - 0.00032 20.6 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_2 PF00891.18 GAM41075.1 - 0.001 18.4 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain DOT1 PF08123.13 GAM41075.1 - 0.0042 16.7 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 GAM41075.1 - 0.005 16.8 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain HTH_9 PF08221.11 GAM41075.1 - 0.015 15.3 0.0 5.2 7.2 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Methyltransf_4 PF02390.17 GAM41075.1 - 0.026 14.0 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase NNMT_PNMT_TEMT PF01234.17 GAM41075.1 - 0.057 12.6 0.0 9.9 5.3 0.0 2.2 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_16 PF10294.9 GAM41075.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase U71 PF17474.2 GAM41075.1 - 0.14 12.1 1.2 0.46 10.5 0.7 2.0 2 0 0 2 2 2 0 Tegument protein UL11 homolog GCD14 PF08704.10 GAM41075.1 - 0.15 11.8 0.0 1.5 8.5 0.0 2.3 2 1 1 3 3 3 0 tRNA methyltransferase complex GCD14 subunit Aminotran_4 PF01063.19 GAM41077.1 - 1.4e-30 106.8 0.0 1.9e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Adaptin_binding PF10199.9 GAM41078.1 - 0.094 13.3 2.6 0.35 11.5 0.0 2.8 1 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 SDP_N PF12278.8 GAM41078.1 - 0.14 12.3 1.8 0.45 10.6 1.8 1.8 1 0 0 1 1 1 0 Sex determination protein N terminal PRELI PF04707.14 GAM41079.1 - 1.8e-24 86.3 0.0 6e-22 78.2 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family HSP70 PF00012.20 GAM41080.1 - 3.7e-11 42.0 0.0 3.5e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 GAM41080.1 - 1.2e-05 24.3 0.0 0.0017 17.2 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 GAM41080.1 - 0.0087 16.5 0.0 0.027 14.9 0.0 2.1 1 1 0 1 1 1 1 Cell division protein FtsA Ribosomal_S14 PF00253.21 GAM41081.1 - 0.071 12.9 0.6 3 7.7 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e Holin_2-3 PF13272.6 GAM41081.1 - 0.089 13.1 1.4 0.31 11.3 0.2 2.0 1 1 1 2 2 2 0 Putative 2/3 transmembrane domain holin FHA PF00498.26 GAM41082.1 - 1.8e-13 50.6 0.1 3.2e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAM41082.1 - 0.0041 17.4 0.0 0.013 15.8 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain BSP_II PF05432.11 GAM41082.1 - 0.0063 16.2 11.9 0.0063 16.2 11.9 2.0 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) TAT_signal PF10518.9 GAM41082.1 - 0.17 11.8 2.8 0.37 10.7 2.8 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence TPR_1 PF00515.28 GAM41083.1 - 2.9e-41 137.6 26.2 4.3e-08 32.6 0.0 11.4 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAM41083.1 - 1.3e-40 134.2 25.8 9.3e-07 28.5 0.0 10.8 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 GAM41083.1 - 3.7e-25 86.0 19.7 4.2e-05 23.4 0.0 10.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAM41083.1 - 2.4e-24 85.7 12.0 3.4e-07 30.8 0.1 7.2 7 1 2 9 9 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 GAM41083.1 - 2.2e-21 74.6 9.5 0.015 15.6 0.0 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAM41083.1 - 4.2e-20 71.2 24.3 9.4e-08 31.6 0.1 8.5 6 1 2 8 8 8 5 TPR repeat TPR_12 PF13424.6 GAM41083.1 - 2.6e-17 62.9 26.4 0.0021 18.3 1.2 8.5 3 1 5 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 GAM41083.1 - 1.8e-16 60.4 20.0 0.00013 22.4 0.4 8.2 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAM41083.1 - 3.8e-16 59.0 9.5 3.6e-07 30.2 0.1 6.1 4 1 3 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAM41083.1 - 1.8e-15 55.7 10.1 0.031 14.3 0.1 9.2 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAM41083.1 - 2.2e-15 56.0 15.3 0.0034 18.1 0.0 9.8 5 2 5 10 10 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM41083.1 - 8.1e-10 38.8 10.8 0.0046 17.1 0.0 5.6 3 1 3 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 GAM41083.1 - 2.5e-07 30.4 18.5 0.76 9.7 0.2 9.4 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM41083.1 - 8.8e-06 25.3 3.4 0.11 11.9 0.8 3.4 3 1 0 4 4 4 2 MalT-like TPR region DUF2397 PF09660.10 GAM41083.1 - 0.0005 19.1 2.9 0.00052 19.0 1.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2397) MAS20 PF02064.15 GAM41083.1 - 0.00053 20.1 9.8 0.041 14.0 2.2 4.2 4 0 0 4 4 4 1 MAS20 protein import receptor TPR_6 PF13174.6 GAM41083.1 - 0.0043 17.6 26.7 40 5.1 0.7 9.8 10 0 0 10 10 10 0 Tetratricopeptide repeat IPPT PF01715.17 GAM41083.1 - 0.0059 16.4 4.0 0.044 13.6 0.3 2.9 2 1 0 3 3 3 1 IPP transferase TPR_4 PF07721.14 GAM41083.1 - 0.0061 17.1 2.5 28 5.7 0.2 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 GAM41083.1 - 0.015 15.4 4.6 16 5.7 0.1 4.6 3 1 0 4 4 3 0 Anaphase-promoting complex subunit 5 SHNi-TPR PF10516.9 GAM41083.1 - 0.023 14.2 8.9 1.8 8.1 0.1 5.9 6 0 0 6 6 6 0 SHNi-TPR NARP1 PF12569.8 GAM41083.1 - 0.029 13.3 23.0 0.9 8.4 0.0 4.8 3 1 3 6 6 6 0 NMDA receptor-regulated protein 1 BCIP PF13862.6 GAM41083.1 - 0.062 13.1 1.5 11 5.8 0.6 2.5 2 0 0 2 2 2 0 p21-C-terminal region-binding protein DUF2561 PF10812.8 GAM41083.1 - 0.11 12.5 0.5 0.2 11.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Sel1 PF08238.12 GAM41083.1 - 0.25 12.1 4.8 13 6.6 0.2 3.8 3 0 0 3 3 2 0 Sel1 repeat DUF3856 PF12968.7 GAM41083.1 - 0.25 11.4 7.5 4 7.5 0.0 5.2 4 3 1 6 6 6 0 Domain of Unknown Function (DUF3856) Serinc PF03348.15 GAM41083.1 - 0.55 9.1 1.6 0.74 8.7 1.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Usp PF00582.26 GAM41083.1 - 3.3 8.2 9.0 4.4 7.8 3.2 3.4 3 1 0 3 3 3 0 Universal stress protein family Abhydrolase_2 PF02230.16 GAM41084.1 - 1.8e-24 86.8 0.5 6.9e-12 45.6 0.1 4.0 2 1 1 3 3 3 3 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 GAM41084.1 - 0.00027 20.5 0.2 0.0019 17.7 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 GAM41084.1 - 0.00067 19.4 0.0 0.0037 17.0 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 GAM41084.1 - 0.023 13.9 0.0 0.056 12.7 0.0 1.6 1 1 1 2 2 2 0 Serine aminopeptidase, S33 LIP PF03583.14 GAM41084.1 - 0.033 13.5 0.1 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase FA_desaturase PF00487.24 GAM41085.1 - 9.3e-17 61.7 20.8 9.3e-17 61.7 20.8 2.1 1 1 1 2 2 2 2 Fatty acid desaturase FliC_SP PF12613.8 GAM41085.1 - 0.098 13.2 1.7 0.19 12.2 1.7 1.4 1 0 0 1 1 1 0 Flagellin structural protein Sec1 PF00995.23 GAM41086.1 - 4.6e-127 425.7 0.0 5.3e-127 425.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family HCV_core PF01542.18 GAM41086.1 - 0.09 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus core protein DUF1043 PF06295.12 GAM41086.1 - 0.43 10.6 2.6 0.56 10.2 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) zf_CCCH_4 PF18345.1 GAM41087.1 - 5.9e-06 26.2 3.7 1e-05 25.4 3.7 1.4 1 0 0 1 1 1 1 Zinc finger domain 14-3-3 PF00244.20 GAM41087.1 - 0.008 15.7 0.4 0.016 14.7 0.4 1.4 1 0 0 1 1 1 1 14-3-3 protein zf-CCCH_4 PF18044.1 GAM41087.1 - 0.01 15.6 1.9 0.016 15.0 1.9 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger Torus PF16131.5 GAM41087.1 - 0.011 16.4 0.1 0.04 14.6 0.1 2.0 1 0 0 1 1 1 0 Torus domain zf-CCCH_3 PF15663.5 GAM41087.1 - 0.02 15.1 0.2 0.055 13.7 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH PF00642.24 GAM41087.1 - 0.033 14.1 1.1 0.052 13.5 1.1 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 GAM41087.1 - 0.13 12.8 1.3 0.21 12.1 1.3 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger AT_hook PF02178.19 GAM41087.1 - 0.31 11.1 6.6 1.3 9.1 6.6 2.2 1 0 0 1 1 1 0 AT hook motif DUF218 PF02698.17 GAM41088.1 - 4.2e-06 26.8 0.0 5.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain HORMA PF02301.18 GAM41089.1 - 6.2e-34 117.4 0.1 7.3e-34 117.2 0.1 1.0 1 0 0 1 1 1 1 HORMA domain DUF2660 PF10859.8 GAM41089.1 - 0.038 14.4 0.7 0.15 12.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2660) Arcadin_1 PF18653.1 GAM41089.1 - 0.064 13.3 0.1 8.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Arcadin 1 Hce2 PF14856.6 GAM41089.1 - 0.08 13.2 0.5 0.17 12.2 0.3 1.6 2 0 0 2 2 2 0 Pathogen effector; putative necrosis-inducing factor Csm1_B PF18211.1 GAM41089.1 - 0.16 11.8 0.7 0.5 10.2 0.1 2.2 2 1 0 2 2 2 0 Csm1 subunit domain B ORC_WH_C PF18137.1 GAM41089.1 - 0.26 11.4 3.4 0.42 10.7 3.4 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal GTP_EFTU PF00009.27 GAM41090.1 - 7.3e-50 169.2 0.0 1.2e-49 168.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 GAM41090.1 - 5.8e-43 145.4 3.8 9.9e-43 144.7 3.8 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 GAM41090.1 - 1.5e-17 63.4 0.0 2.8e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAM41090.1 - 3.6e-06 27.3 0.1 8.6e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 GAM41090.1 - 1.7e-05 24.4 0.0 0.00027 20.6 0.0 2.3 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 GAM41090.1 - 3.9e-05 23.7 0.0 0.0001 22.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 GAM41090.1 - 0.0073 16.4 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 GAM41090.1 - 0.0094 15.4 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RF3_C PF16658.5 GAM41090.1 - 0.013 15.3 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Cupin_2 PF07883.11 GAM41091.1 - 0.11 12.3 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Cupin domain Opy2 PF09463.10 GAM41092.1 - 7.1e-05 23.0 24.1 0.00011 22.4 24.1 1.3 1 0 0 1 1 1 1 Opy2 protein SKG6 PF08693.10 GAM41092.1 - 0.004 16.5 1.8 0.0089 15.4 1.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PTP_tm PF18861.1 GAM41092.1 - 0.09 12.8 0.3 0.16 11.9 0.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Podoplanin PF05808.11 GAM41092.1 - 0.37 10.9 0.0 0.37 10.9 0.0 3.4 2 1 0 2 2 2 0 Podoplanin Rad51 PF08423.11 GAM41093.1 - 0.006 15.9 0.0 0.0098 15.2 0.0 1.3 1 0 0 1 1 1 1 Rad51 PSY3 PF16836.5 GAM41093.1 - 0.018 14.6 0.0 0.058 12.9 0.0 1.6 1 1 0 1 1 1 0 Shu complex component Psy3, DNA-binding description Adeno_IVa2 PF02456.15 GAM41093.1 - 0.19 10.5 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein Lactamase_B PF00753.27 GAM41094.1 - 4.2e-18 66.1 0.6 5.3e-18 65.7 0.6 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM41094.1 - 0.019 14.5 0.0 0.03 13.8 0.0 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAM41094.1 - 0.14 12.1 0.2 1.9 8.4 0.2 2.2 1 1 0 1 1 1 0 Beta-lactamase superfamily domain NmrA PF05368.13 GAM41095.1 - 1e-23 84.1 0.8 1.2e-23 83.9 0.8 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM41095.1 - 3.8e-18 66.0 0.0 6.1e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM41095.1 - 7.8e-06 25.5 0.0 2.2e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAM41095.1 - 0.00014 22.1 0.2 0.00047 20.4 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 GAM41095.1 - 0.00095 18.5 0.6 0.0066 15.8 0.6 2.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 GAM41095.1 - 0.0027 17.1 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 GAM41095.1 - 0.005 17.3 0.1 0.013 15.9 0.1 2.0 1 1 0 1 1 1 1 Putative NAD(P)-binding adh_short PF00106.25 GAM41095.1 - 0.012 15.1 0.1 0.028 13.9 0.1 1.7 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 GAM41095.1 - 0.02 15.0 0.4 0.042 14.0 0.1 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 GAM41095.1 - 0.023 13.8 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.18 GAM41095.1 - 0.023 14.6 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 GAM41095.1 - 0.066 13.9 1.2 0.22 12.2 0.1 2.3 3 0 0 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Abhydrolase_6 PF12697.7 GAM41096.1 - 1.4e-21 78.1 1.3 1.6e-21 77.9 1.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM41096.1 - 0.00014 21.2 0.0 0.00087 18.6 0.0 2.2 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM41096.1 - 0.00018 21.3 0.1 0.00036 20.2 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 GAM41096.1 - 0.00079 19.1 0.3 0.005 16.5 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase DUF676 PF05057.14 GAM41096.1 - 0.0017 17.9 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 GAM41096.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 GAM41096.1 - 0.037 13.6 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.18 GAM41096.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 2) DUF3224 PF11528.8 GAM41097.1 - 1.4e-26 92.7 0.0 1.6e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3224) DUF2341 PF10102.9 GAM41097.1 - 0.11 13.1 0.0 0.3 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2341) Mitochondr_Som1 PF11093.8 GAM41098.1 - 7.9e-24 83.5 0.0 9.5e-24 83.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 TAF8_C PF10406.9 GAM41099.1 - 2.9e-21 75.8 0.9 8e-21 74.3 0.9 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 GAM41099.1 - 2.4e-09 37.1 0.0 4.4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated UQ_con PF00179.26 GAM41100.1 - 2.4e-38 130.9 0.0 3.2e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM41100.1 - 0.04 13.6 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Chitin_synth_1 PF01644.17 GAM41101.1 - 2.1e-70 235.9 0.0 8.2e-70 234.0 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.11 GAM41101.1 - 2.3e-28 97.9 0.0 4.5e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAM41101.1 - 1.9e-24 86.2 0.1 1e-19 70.6 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAM41101.1 - 9.4e-09 35.5 0.1 9.4e-09 35.5 0.1 2.5 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAM41101.1 - 0.0038 17.1 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PALP PF00291.25 GAM41102.1 - 4.7e-70 236.3 0.1 5.8e-70 236.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 GAM41102.1 - 0.0083 16.1 0.1 3.3 7.7 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase DegT_DnrJ_EryC1 PF01041.17 GAM41102.1 - 0.032 13.5 0.1 0.054 12.8 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IlvN PF07991.12 GAM41103.1 - 1.1e-45 155.1 0.0 1.7e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 GAM41103.1 - 2.6e-40 138.0 0.0 4e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 GAM41103.1 - 0.045 13.9 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2OG-FeII_Oxy_2 PF13532.6 GAM41104.1 - 1.4e-25 90.7 0.0 2.4e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 GAM41104.1 - 3.7e-20 72.8 0.0 1e-19 71.4 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family GST_C_2 PF13410.6 GAM41104.1 - 8.3e-06 25.7 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM41104.1 - 1.4e-05 25.2 0.0 3.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM41104.1 - 0.0003 20.9 0.0 0.00068 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PAS_3 PF08447.12 GAM41104.1 - 0.054 13.8 0.1 5.9 7.2 0.0 3.0 2 0 0 2 2 2 0 PAS fold ECH_1 PF00378.20 GAM41105.1 - 6.4e-38 130.5 0.1 3e-37 128.3 0.1 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM41105.1 - 1.1e-29 104.0 0.0 2.9e-27 96.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Phage_Capsid_P3 PF09018.11 GAM41105.1 - 0.078 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 P3 major capsid protein Tfb5 PF06331.12 GAM41106.1 - 1.4e-24 85.8 0.7 1.6e-24 85.7 0.7 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 HSP20 PF00011.21 GAM41107.1 - 1.5e-18 66.8 0.2 4.4e-13 49.2 0.0 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAM41107.1 - 8.8e-06 25.2 0.0 7.7e-05 22.2 0.0 2.2 1 1 0 1 1 1 1 HSP20-like domain found in ArsA MFS_1 PF07690.16 GAM41108.1 - 9.8e-42 143.1 43.9 9.8e-42 143.1 43.9 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM41108.1 - 6.8e-12 45.0 11.9 6.8e-12 45.0 11.9 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 GAM41108.1 - 4.2e-09 36.2 2.9 4.2e-09 36.2 2.9 2.5 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB PUCC PF03209.15 GAM41108.1 - 2.8e-06 26.6 19.2 0.00053 19.1 4.9 2.7 2 1 0 2 2 2 2 PUCC protein OATP PF03137.20 GAM41108.1 - 0.00065 18.1 11.6 0.00074 17.9 2.0 2.5 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF2270 PF10028.9 GAM41108.1 - 0.098 12.2 0.0 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) Tmpp129 PF10272.9 GAM41109.1 - 0.15 11.3 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Glyco_hydro_53 PF07745.13 GAM41111.1 - 1.2e-100 336.8 0.0 1.5e-100 336.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 GGACT PF06094.12 GAM41111.1 - 2.9e-07 31.1 0.1 9.3e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 GAM41111.1 - 0.00062 20.1 0.1 0.0047 17.3 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family Amidoligase_2 PF12224.8 GAM41112.1 - 1.8e-15 57.3 0.0 2.7e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme GGACT PF06094.12 GAM41113.1 - 5.2e-07 30.3 0.1 2.2e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 GAM41113.1 - 6e-05 23.4 0.0 0.00033 21.0 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family Rtf2 PF04641.12 GAM41113.1 - 0.079 12.3 2.5 0.12 11.8 2.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Amidoligase_2 PF12224.8 GAM41114.1 - 2.6e-15 56.8 0.0 3.5e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme SLC35F PF06027.12 GAM41115.1 - 6e-89 298.5 27.8 7e-89 298.3 27.8 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 GAM41115.1 - 4.7e-09 35.6 4.7 8.9e-09 34.7 4.3 1.6 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 GAM41115.1 - 0.001 19.2 38.6 0.0036 17.5 13.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family Ank_2 PF12796.7 GAM41116.1 - 5.9e-16 58.8 6.8 7e-09 36.2 0.9 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM41116.1 - 3.9e-12 45.2 3.4 0.00051 20.3 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 GAM41116.1 - 7.6e-09 35.6 4.4 1.7e-05 25.0 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAM41116.1 - 2.1e-08 34.3 1.6 0.00016 21.9 0.3 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM41116.1 - 2.4e-08 34.3 1.0 1.8e-07 31.6 0.2 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) F-box-like PF12937.7 GAM41116.1 - 0.015 15.1 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 F-box-like DLH PF01738.18 GAM41117.1 - 1.8e-14 53.8 0.0 2.4e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 GAM41117.1 - 0.086 13.4 0.1 0.16 12.5 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Acetyltransf_1 PF00583.25 GAM41118.1 - 6.8e-10 39.2 0.0 1e-09 38.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM41118.1 - 2.8e-09 37.0 0.0 5.3e-09 36.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM41118.1 - 1.3e-08 35.1 0.0 4e-08 33.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM41118.1 - 1.8e-05 24.8 0.0 0.007 16.4 0.0 2.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM41118.1 - 0.047 13.7 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 GAM41118.1 - 0.068 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ADH_N PF08240.12 GAM41119.1 - 4.8e-30 103.7 0.6 8.8e-30 102.8 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM41119.1 - 4.8e-14 52.5 0.2 2.6e-13 50.1 0.1 2.2 2 1 1 3 3 3 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAM41119.1 - 2.9e-07 30.2 0.1 0.008 15.7 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus 3HCDH_N PF02737.18 GAM41119.1 - 0.00014 21.8 0.1 0.00022 21.2 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 GAM41119.1 - 0.0033 16.7 0.2 0.005 16.1 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAM41119.1 - 0.012 14.9 0.1 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAM41119.1 - 0.023 14.0 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 GAM41119.1 - 0.033 15.2 0.0 0.077 14.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox PF00070.27 GAM41119.1 - 0.036 14.6 0.1 0.11 13.1 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 GAM41120.1 - 2.7e-45 154.8 0.0 3.9e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM41120.1 - 2.5e-25 89.2 0.0 3.9e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM41120.1 - 0.00044 19.6 0.0 0.0032 16.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 GAM41120.1 - 0.057 13.3 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 GAM41120.1 - 0.076 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Copper-fist PF00649.18 GAM41121.1 - 1.7e-22 78.6 2.3 2.5e-22 78.0 2.3 1.3 1 0 0 1 1 1 1 Copper fist DNA binding domain SOG2 PF10428.9 GAM41121.1 - 0.85 8.8 10.3 0.94 8.6 10.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein QWRF PF04484.12 GAM41121.1 - 4.3 7.0 9.5 5 6.8 9.5 1.3 1 0 0 1 1 1 0 QWRF family CiPC PF15800.5 GAM41121.1 - 8.2 6.0 14.6 9.1 5.9 14.1 1.4 1 1 0 1 1 1 0 Clock interacting protein circadian CMD PF02627.20 GAM41122.1 - 3.4e-07 30.2 0.2 7e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Lactonase PF10282.9 GAM41123.1 - 1.1e-21 77.5 0.0 1.7e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Frag1 PF10277.9 GAM41123.1 - 3.3e-18 66.0 9.3 5.5e-18 65.3 9.3 1.3 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Glyco_hydro_3_C PF01915.22 GAM41124.1 - 1e-47 162.8 0.0 1.7e-47 162.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAM41124.1 - 1e-38 133.5 0.0 1.8e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM41124.1 - 1.1e-20 73.5 0.1 2.1e-20 72.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Catalase PF00199.19 GAM41126.1 - 1.2e-162 541.5 0.0 1.4e-162 541.2 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 GAM41126.1 - 9.9e-48 161.6 1.2 1.8e-47 160.8 1.2 1.5 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 GAM41126.1 - 7.2e-16 58.2 0.0 1.3e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive MFS_1 PF07690.16 GAM41127.1 - 2.7e-09 36.4 15.5 3.6e-09 36.0 15.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAM41127.1 - 1.2e-06 28.4 4.8 1.2e-06 28.4 4.8 1.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_2 PF13347.6 GAM41127.1 - 0.0014 17.3 3.3 0.0023 16.6 3.3 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.24 GAM41127.1 - 0.0037 16.2 4.2 0.0037 16.2 4.2 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter PUCC PF03209.15 GAM41127.1 - 0.19 10.7 6.0 0.42 9.6 6.0 1.6 1 1 0 1 1 1 0 PUCC protein Sugar_tr PF00083.24 GAM41128.1 - 7.9e-101 338.1 20.6 9.1e-101 337.9 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM41128.1 - 1.9e-23 83.0 27.4 1.9e-23 83.0 27.4 2.5 2 1 1 3 3 3 1 Major Facilitator Superfamily TPR_19 PF14559.6 GAM41128.1 - 0.065 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Transferase PF02458.15 GAM41129.1 - 4.9e-06 25.5 0.0 2.4e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Transferase family PHD_4 PF16866.5 GAM41130.1 - 0.013 15.6 13.3 0.064 13.3 13.3 2.2 1 0 0 1 1 1 0 PHD-finger Baculo_PEP_C PF04513.12 GAM41130.1 - 0.013 15.5 2.3 0.019 15.0 2.3 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lipase_GDSL PF00657.22 GAM41130.1 - 0.016 15.2 0.5 0.2 11.6 0.6 2.0 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase PHD PF00628.29 GAM41130.1 - 0.022 14.6 15.1 0.04 13.8 15.1 1.4 1 0 0 1 1 1 0 PHD-finger DivIC PF04977.15 GAM41130.1 - 0.031 14.0 9.8 0.55 10.0 4.8 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 GAM41130.1 - 0.037 14.1 0.9 0.088 12.8 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 GAM41130.1 - 0.052 13.6 18.6 0.091 12.8 18.6 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 GAM41130.1 - 0.058 13.7 4.9 0.34 11.2 4.8 2.2 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 GAM41130.1 - 0.059 13.8 20.5 0.037 14.5 13.1 2.8 2 1 0 2 2 2 0 Cell division protein ZapB DUF2730 PF10805.8 GAM41130.1 - 0.16 12.1 2.4 0.38 10.9 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) FlaC_arch PF05377.11 GAM41130.1 - 0.18 12.2 2.0 19 5.8 0.1 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 GAM41130.1 - 0.48 10.6 9.5 6.9 6.8 4.6 2.6 2 0 0 2 2 2 0 Basic region leucine zipper HALZ PF02183.18 GAM41130.1 - 1.1 9.5 11.3 3.7 7.9 4.9 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.8 GAM41130.1 - 1.1 9.4 15.0 4.2 7.6 14.7 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding zf-4CXXC_R1 PF10497.9 GAM41130.1 - 1.2 9.4 13.0 0.13 12.5 8.2 1.9 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF3450 PF11932.8 GAM41130.1 - 1.2 8.3 15.4 0.021 14.2 7.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FAM209 PF15206.6 GAM41130.1 - 2.1 8.1 6.7 3.7 7.3 5.1 2.1 1 1 1 2 2 2 0 FAM209 family GAS PF13851.6 GAM41130.1 - 2.7 7.3 21.1 0.046 13.1 12.1 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 GAM41130.1 - 2.9 7.7 13.6 0.23 11.2 7.2 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 WD40_alt PF14077.6 GAM41130.1 - 6 6.8 6.8 2.3 8.2 0.6 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF4381 PF14316.6 GAM41131.1 - 0.068 13.4 0.8 4.3 7.6 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) FAD_binding_4 PF01565.23 GAM41132.1 - 8e-22 77.5 1.4 3e-21 75.6 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAM41132.1 - 0.016 15.3 0.1 0.049 13.7 0.1 1.9 1 0 0 1 1 1 0 Berberine and berberine like p450 PF00067.22 GAM41133.1 - 1.2e-53 182.5 0.0 1.5e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1382 PF07131.11 GAM41134.1 - 0.01 15.8 0.1 7.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1382) MFS_1 PF07690.16 GAM41138.1 - 3.7e-36 124.8 25.1 5.6e-36 124.2 25.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CoA_trans PF01144.23 GAM41139.1 - 2.8e-97 324.4 1.5 7.3e-62 208.6 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 GAM41139.1 - 0.00089 19.2 0.1 0.0017 18.3 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mannitol_dh_C PF08125.13 GAM41139.1 - 0.1 12.0 0.1 0.32 10.4 0.1 1.8 2 0 0 2 2 2 0 Mannitol dehydrogenase C-terminal domain Zn_clus PF00172.18 GAM41140.1 - 0.00013 22.0 7.1 0.00029 20.9 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5327 PF17261.2 GAM41140.1 - 0.0017 19.1 1.4 0.0042 17.8 1.4 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5327) Lactamase_B PF00753.27 GAM41141.1 - 4.4e-16 59.5 2.1 8.1e-16 58.6 2.1 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM41141.1 - 4.8e-05 23.0 0.2 7.8e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAM41141.1 - 0.022 14.6 0.1 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.14 GAM41142.1 - 1.2e-11 44.4 0.0 2.9e-08 33.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM41142.1 - 0.0015 18.2 0.3 0.0024 17.5 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM41142.1 - 0.0065 16.5 0.0 0.058 13.4 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GAM41142.1 - 0.093 12.0 0.0 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 GAM41142.1 - 0.097 12.9 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 GAM41142.1 - 0.2 12.3 0.1 4.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM41142.1 - 0.2 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 GAM41142.1 - 0.23 10.3 0.2 0.32 9.8 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase cobW PF02492.19 GAM41143.1 - 1e-49 168.5 4.9 3.4e-37 127.7 0.6 2.5 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAM41143.1 - 5.3e-20 71.1 0.1 6.7e-16 58.0 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 GAM41143.1 - 0.0013 18.3 1.5 0.25 10.8 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 GAM41143.1 - 0.0018 17.3 0.5 0.58 9.1 0.0 2.9 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 GAM41143.1 - 0.0019 18.1 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 GAM41143.1 - 0.0027 18.1 0.9 0.033 14.6 0.9 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 GAM41143.1 - 0.014 15.9 0.6 0.084 13.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAM41143.1 - 0.035 14.3 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAM41143.1 - 0.046 13.7 0.1 0.046 13.7 0.1 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 GAM41143.1 - 0.05 12.7 0.1 0.05 12.7 0.1 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 GAM41143.1 - 0.051 12.5 0.0 0.73 8.7 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.18 GAM41143.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 GAM41143.1 - 0.17 11.6 0.1 0.41 10.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GAM41143.1 - 0.21 11.9 0.9 1.3 9.3 0.9 2.4 1 1 0 1 1 1 0 AAA domain TauD PF02668.16 GAM41144.1 - 5.1e-52 177.3 0.0 5.8e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans PF04082.18 GAM41145.1 - 2.2e-12 46.6 0.0 3.9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM41145.1 - 7.2e-07 29.2 13.1 1.7e-06 28.0 13.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 GAM41146.1 - 2.4e-27 95.8 48.4 8.7e-19 67.7 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SURF4 PF02077.15 GAM41146.1 - 0.022 14.4 0.1 0.022 14.4 0.1 2.5 3 0 0 3 3 3 0 SURF4 family TMEM171 PF15471.6 GAM41146.1 - 3.2 6.6 10.8 1.8 7.5 0.0 3.7 4 1 0 4 4 4 0 Transmembrane protein family 171 PBP PF01161.20 GAM41147.1 - 1.2e-08 35.3 0.4 4.5e-08 33.5 0.1 1.9 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein CMAS PF02353.20 GAM41148.1 - 6.2e-77 258.6 0.0 9.3e-77 258.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 GAM41148.1 - 9.3e-15 55.1 0.0 2.2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM41148.1 - 1.4e-13 51.2 0.0 3.5e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM41148.1 - 1e-12 48.2 0.0 2.2e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM41148.1 - 1.3e-08 35.5 0.0 3.1e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM41148.1 - 1.6e-07 31.3 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 GAM41148.1 - 0.00027 20.6 0.0 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.19 GAM41148.1 - 0.00056 19.7 0.0 0.00086 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 GAM41148.1 - 0.00097 18.7 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 GAM41148.1 - 0.066 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_9 PF08003.11 GAM41148.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.18 GAM41148.1 - 0.19 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain MFS_1 PF07690.16 GAM41150.1 - 2.4e-42 145.2 62.1 2.6e-41 141.7 60.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily UcrQ PF02939.16 GAM41150.1 - 9.2e-31 105.6 0.3 3.1e-30 103.9 0.3 2.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 GAM41150.1 - 0.07 13.5 0.0 0.28 11.6 0.0 2.0 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 adh_short PF00106.25 GAM41151.1 - 2.4e-23 82.6 0.0 2e-22 79.6 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM41151.1 - 5.2e-12 45.8 0.0 1.1e-11 44.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM41151.1 - 6.5e-10 39.2 0.1 9.9e-10 38.6 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM41151.1 - 2e-06 27.4 0.1 3.1e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM41151.1 - 0.00011 21.7 0.1 0.00024 20.6 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF3425 PF11905.8 GAM41152.1 - 1.1e-17 64.2 1.6 1.4e-17 63.9 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Fungal_trans PF04082.18 GAM41153.1 - 6.3e-07 28.7 0.1 1.2e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SAC3_GANP PF03399.16 GAM41153.1 - 0.001 18.6 0.3 0.0017 17.8 0.3 1.4 1 0 0 1 1 1 1 SAC3/GANP family NmrA PF05368.13 GAM41154.1 - 7.8e-48 163.1 0.0 1.1e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM41154.1 - 2.6e-11 43.8 0.0 4.5e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAM41154.1 - 0.019 14.0 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 GAM41154.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain FMN_red PF03358.15 GAM41155.1 - 2.2e-31 108.7 0.0 2.8e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAM41155.1 - 5.2e-08 32.8 0.0 7.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Aldo_ket_red PF00248.21 GAM41156.1 - 2.6e-75 253.4 0.0 2.9e-75 253.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 GAM41157.1 - 3.1e-20 72.3 2.3 5.7e-20 71.5 2.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM41157.1 - 3.3e-09 36.7 7.7 6.5e-09 35.8 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphoesterase PF04185.14 GAM41158.1 - 4.1e-32 111.7 2.7 7.2e-31 107.7 2.7 2.1 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 GAM41158.1 - 0.19 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain FGFR3_TM PF18123.1 GAM41159.1 - 5.8 6.5 8.8 1.1 8.8 4.5 2.1 2 0 0 2 2 2 0 Fibroblast growth factor receptor 3 transmembrane domain Transp_cyt_pur PF02133.15 GAM41160.1 - 2.5e-18 66.1 37.8 1.2e-17 63.9 37.8 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PDR_assoc PF08370.11 GAM41160.1 - 0.045 13.5 1.6 0.11 12.3 0.2 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Fzo_mitofusin PF04799.13 GAM41160.1 - 1.1 8.8 2.1 1.8 8.1 2.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region 2OG-FeII_Oxy_3 PF13640.6 GAM41161.1 - 5.2e-10 40.1 0.2 9.6e-10 39.2 0.1 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Thioredoxin_6 PF13848.6 GAM41162.1 - 2.6e-16 60.1 0.0 3.9e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 GAM41162.1 - 6.4e-11 42.2 0.0 2.6e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Transferase PF02458.15 GAM41164.1 - 8.3e-15 54.4 0.0 1.4e-10 40.4 0.0 2.5 1 1 1 2 2 2 2 Transferase family NmrA PF05368.13 GAM41165.1 - 1.8e-23 83.3 0.0 2.5e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM41165.1 - 6.3e-19 68.6 0.0 1.6e-18 67.3 0.0 1.7 1 1 1 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 GAM41165.1 - 6.6e-06 26.6 0.2 0.00032 21.1 0.0 2.4 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 GAM41165.1 - 0.0016 17.9 0.0 0.0072 15.8 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 GAM41165.1 - 0.0023 18.0 0.3 0.0071 16.5 0.1 1.9 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 GAM41165.1 - 0.0038 16.4 0.1 0.029 13.6 0.0 2.2 3 0 0 3 3 3 1 Male sterility protein THF_DHG_CYH_C PF02882.19 GAM41165.1 - 0.019 14.3 0.1 0.28 10.5 0.1 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 GAM41165.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_106 PF17132.4 GAM41166.1 - 2e-14 52.9 0.0 3.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 alpha-L-rhamnosidase Fungal_trans PF04082.18 GAM41166.1 - 1.5e-11 43.9 0.0 2.4e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM41166.1 - 5.7e-08 32.8 10.9 9.3e-08 32.1 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_trans_2_3 PF13632.6 GAM41167.1 - 5.9e-35 121.0 1.1 1.2e-34 120.0 1.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Ank_2 PF12796.7 GAM41168.1 - 3.4e-81 267.9 0.2 3.1e-12 46.9 0.0 10.5 5 3 6 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM41168.1 - 5.8e-63 208.5 14.8 1.4e-08 35.1 0.0 15.4 6 4 13 19 19 19 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM41168.1 - 2.6e-58 187.1 21.9 0.0014 18.9 0.0 20.8 22 0 0 22 22 22 12 Ankyrin repeat Ank_5 PF13857.6 GAM41168.1 - 1.4e-46 155.9 17.7 1.2e-06 28.7 0.1 14.3 8 6 6 15 15 15 11 Ankyrin repeats (many copies) Ank PF00023.30 GAM41168.1 - 7.1e-44 146.4 20.8 0.0037 17.6 0.1 17.7 18 0 0 18 18 18 11 Ankyrin repeat DUF2457 PF10446.9 GAM41168.1 - 0.01 15.0 0.8 0.01 15.0 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Peptidase_S8 PF00082.22 GAM41170.1 - 1.7e-15 57.1 0.0 3.4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 GAM41170.1 - 4.6e-06 27.1 0.2 0.099 13.2 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM41170.1 - 2.1e-05 25.0 0.0 0.0089 16.6 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAM41170.1 - 0.00073 19.9 0.0 0.39 11.3 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 GAM41170.1 - 0.002 18.5 0.0 3.6 8.4 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat DUF4551 PF15087.6 GAM41170.1 - 0.18 10.6 5.7 0.28 10.0 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Dabb PF07876.12 GAM41171.1 - 5.7e-12 46.1 0.0 6.9e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ABM PF03992.16 GAM41171.1 - 0.031 14.4 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase FAD_binding_3 PF01494.19 GAM41172.1 - 8.3e-47 160.1 0.0 1e-46 159.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM41172.1 - 3.9e-07 30.0 1.1 6.4e-05 22.7 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM41172.1 - 3.3e-06 27.2 0.3 8.2e-06 26.0 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM41172.1 - 1.1e-05 24.8 0.0 0.00025 20.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM41172.1 - 1.4e-05 25.5 0.1 8.2e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM41172.1 - 0.00026 20.3 0.1 0.00087 18.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 GAM41172.1 - 0.00084 18.7 0.0 0.0023 17.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM41172.1 - 0.00085 18.1 0.1 0.0042 15.8 0.0 2.0 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 GAM41172.1 - 0.0074 15.4 0.2 0.015 14.4 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 GAM41172.1 - 0.012 16.0 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 GAM41172.1 - 0.024 13.7 0.1 0.058 12.4 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 GAM41172.1 - 0.032 13.9 0.2 0.068 12.8 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 GAM41172.1 - 0.041 13.2 0.1 2 7.7 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 GAM41172.1 - 0.06 13.9 0.1 0.16 12.5 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain TrkA_N PF02254.18 GAM41172.1 - 0.071 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 GAM41172.1 - 0.14 11.8 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 GAM41172.1 - 0.17 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 GAM41172.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_Gly3P_dh_N PF01210.23 GAM41172.1 - 0.19 11.7 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short PF00106.25 GAM41173.1 - 7.2e-32 110.4 0.1 1e-31 109.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM41173.1 - 1e-23 84.2 0.1 1.3e-23 83.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM41173.1 - 5.2e-09 36.3 0.0 6.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM41173.1 - 4.7e-06 26.2 0.0 1.2e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM41173.1 - 0.00055 19.4 0.0 0.0074 15.7 0.0 2.5 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GAM41173.1 - 0.005 16.0 0.0 0.011 14.9 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 GAM41173.1 - 0.04 14.4 0.0 0.8 10.1 0.0 2.4 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 GAM41173.1 - 0.089 11.9 0.0 0.17 11.0 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 GAM41173.1 - 0.11 12.7 0.1 0.48 10.7 0.1 2.0 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 GAM41174.1 - 1.3e-32 113.1 37.1 1.8e-32 112.6 37.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM41174.1 - 5.2e-07 29.3 8.9 5.2e-07 29.3 8.9 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Spc110_C PF18520.1 GAM41174.1 - 0.0071 15.9 0.1 0.016 14.8 0.1 1.6 1 0 0 1 1 1 1 Spindle pole body component 110 C-terminal domain AAT PF03417.16 GAM41175.1 - 2.5e-06 27.4 0.0 4.8e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Peptidase_A4 PF01828.17 GAM41176.1 - 1.9e-51 174.5 7.9 1.9e-51 174.5 7.9 1.9 2 0 0 2 2 2 1 Peptidase A4 family ADH_zinc_N PF00107.26 GAM41176.1 - 1.1e-07 31.8 1.1 3.2e-07 30.4 1.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 GAM41176.1 - 0.014 14.9 0.0 0.048 13.1 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 GAM41176.1 - 0.04 13.8 0.2 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.17 GAM41176.1 - 0.17 10.9 0.2 0.33 10.0 0.2 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Sugar_tr PF00083.24 GAM41177.1 - 1.1e-110 370.6 25.5 1.3e-110 370.3 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM41177.1 - 1.2e-14 54.0 40.6 5.2e-09 35.5 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OppC_N PF12911.7 GAM41177.1 - 0.38 10.8 4.7 0.22 11.5 0.7 2.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF1100 PF06500.11 GAM41178.1 - 0.0018 17.1 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 GAM41178.1 - 0.005 17.5 0.8 0.014 16.0 0.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAM41178.1 - 0.014 15.0 0.0 0.24 10.9 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.11 GAM41178.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Fungal_trans PF04082.18 GAM41180.1 - 0.0013 17.9 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 GAM41181.1 - 6.2e-34 117.2 0.0 2e-33 115.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM41181.1 - 5.7e-32 111.1 0.0 4.5e-31 108.2 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM41181.1 - 2.3e-10 40.7 0.2 2.3e-10 40.7 0.2 1.5 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 GAM41181.1 - 0.0025 16.9 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAM41181.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 GAM41181.1 - 0.023 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM41181.1 - 0.027 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 GAM41181.1 - 0.03 14.4 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 GAM41181.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase KR PF08659.10 GAM41182.1 - 3e-52 177.1 0.0 5.1e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 GAM41182.1 - 3.2e-18 66.3 0.0 1.1e-17 64.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 GAM41182.1 - 1.9e-11 45.1 0.0 3.6e-10 41.0 0.0 3.1 3 1 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAM41182.1 - 1.9e-11 44.0 0.0 6.2e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 GAM41182.1 - 7.1e-11 42.1 0.0 2.8e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM41182.1 - 1.8e-10 41.4 0.1 1e-09 38.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 GAM41182.1 - 5.5e-10 39.5 0.0 1.2e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 GAM41182.1 - 3.3e-09 37.3 0.0 2e-08 34.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM41182.1 - 5.1e-07 29.7 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 GAM41182.1 - 1.6e-05 24.5 0.0 3.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Ubie_methyltran PF01209.18 GAM41182.1 - 6.2e-05 22.4 0.0 0.00016 21.1 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PS-DH PF14765.6 GAM41182.1 - 6.3e-05 22.4 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_N PF08240.12 GAM41182.1 - 0.00026 20.8 0.1 0.00054 19.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_28 PF02636.17 GAM41182.1 - 0.013 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 GAM41182.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Lactamase_B PF00753.27 GAM41183.1 - 8e-11 42.3 2.4 1.2e-10 41.7 1.7 1.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM41183.1 - 0.00012 21.7 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FAD_binding_3 PF01494.19 GAM41184.1 - 1.5e-18 67.2 4.5 4.6e-11 42.6 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAM41184.1 - 1.9e-05 24.4 1.4 7.5e-05 22.5 0.7 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM41184.1 - 4.8e-05 22.7 1.6 0.018 14.3 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM41184.1 - 0.00013 21.2 2.4 0.00013 21.2 1.3 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GAM41184.1 - 0.00019 21.6 2.8 0.00028 21.1 0.5 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GAM41184.1 - 0.0003 20.3 0.1 0.00042 19.8 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM41184.1 - 0.0009 18.0 0.4 0.0013 17.5 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAM41184.1 - 0.034 13.4 0.1 0.057 12.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM41184.1 - 0.075 12.1 0.1 0.089 11.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 GAM41184.1 - 0.079 13.5 3.0 2 9.0 0.4 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM41184.1 - 0.19 10.6 0.8 1.2 7.9 0.2 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Transferase PF02458.15 GAM41185.1 - 1.4e-12 47.0 0.0 1.4e-09 37.1 0.0 2.5 2 1 0 2 2 2 2 Transferase family GMC_oxred_N PF00732.19 GAM41186.1 - 4.3e-57 193.7 0.0 5.8e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM41186.1 - 2.8e-34 118.7 0.1 7.1e-34 117.4 0.0 1.7 2 0 0 2 2 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 GAM41186.1 - 7.6e-08 32.0 0.1 0.0074 15.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM41186.1 - 1.6e-05 24.2 0.2 0.019 14.1 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAM41186.1 - 2.6e-05 23.6 0.1 0.00015 21.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM41186.1 - 3.6e-05 23.1 0.1 0.0005 19.4 0.1 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 GAM41186.1 - 3.7e-05 23.5 0.6 0.00063 19.4 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAM41186.1 - 0.00014 21.0 0.1 0.00022 20.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAM41186.1 - 0.0007 19.8 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAM41186.1 - 0.0075 16.3 0.8 0.014 15.4 0.1 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 GAM41186.1 - 0.014 14.3 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 GAM41186.1 - 0.036 12.8 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 GAM41186.1 - 0.094 11.9 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 GAM41186.1 - 0.14 12.4 0.1 0.42 10.9 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 GAM41187.1 - 5.9e-58 195.7 0.1 1.8e-57 194.2 0.0 2.0 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 GAM41187.1 - 1e-53 182.5 0.0 1.7e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAM41187.1 - 1.1e-44 153.2 0.0 2.9e-44 151.9 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM41187.1 - 1.8e-36 124.7 0.0 4.2e-36 123.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 GAM41187.1 - 4.5e-29 101.8 0.1 7.7e-21 74.8 0.0 3.4 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ADH_zinc_N_2 PF13602.6 GAM41187.1 - 5.5e-16 59.8 0.0 2.7e-14 54.4 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAM41187.1 - 4.7e-15 55.7 0.0 3e-14 53.1 0.1 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 GAM41187.1 - 1.1e-12 47.8 0.4 5.4e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 GAM41187.1 - 9.2e-11 41.9 0.0 1.9e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM41187.1 - 5.2e-10 40.0 0.0 1.5e-09 38.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM41187.1 - 8e-09 36.1 0.0 9e-08 32.7 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAM41187.1 - 1.4e-08 35.1 0.0 4.7e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short_C2 PF13561.6 GAM41187.1 - 4.9e-07 29.5 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_11 PF08241.12 GAM41187.1 - 5.3e-06 27.0 0.0 2.2e-05 25.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 GAM41187.1 - 6.4e-06 26.4 0.3 2.1e-05 24.8 0.3 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 GAM41187.1 - 4.6e-05 23.2 0.1 0.00011 22.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.6 GAM41187.1 - 0.00058 19.7 0.0 0.0034 17.2 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain GDP_Man_Dehyd PF16363.5 GAM41187.1 - 0.0012 18.4 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Ubie_methyltran PF01209.18 GAM41187.1 - 0.012 14.9 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family p450 PF00067.22 GAM41188.1 - 3e-42 145.0 0.0 7.3e-42 143.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Myb_DNA-binding PF00249.31 GAM41189.1 - 0.069 13.4 0.5 0.15 12.3 0.5 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DNA_pol_phi PF04931.13 GAM41189.1 - 1.6 6.8 4.5 1.8 6.6 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi adh_short PF00106.25 GAM41190.1 - 8.1e-20 71.1 0.5 1.6e-19 70.1 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAM41190.1 - 3.8e-10 39.9 0.7 5.9e-10 39.3 0.1 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 GAM41190.1 - 5.3e-09 36.0 0.0 1.9e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAM41190.1 - 3.2e-05 23.5 0.1 7.8e-05 22.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAM41190.1 - 0.042 13.9 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 GAM41190.1 - 0.058 12.5 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 GAM41191.1 - 2e-10 40.1 0.1 3.7e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DASH_Dad2 PF08654.10 GAM41191.1 - 0.0047 17.3 0.1 0.013 15.9 0.1 1.7 1 0 0 1 1 1 1 DASH complex subunit Dad2 p450 PF00067.22 GAM41192.1 - 5.4e-43 147.4 0.0 1e-42 146.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 GAM41193.1 - 9.6e-78 261.3 0.0 1.7e-77 260.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAM41193.1 - 2.6e-35 121.0 1.1 4.4e-35 120.2 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 GAM41193.1 - 5.9e-23 80.6 0.0 1.9e-22 78.9 0.0 1.9 2 0 0 2 2 1 1 Helix-turn-helix domain PS-DH PF14765.6 GAM41193.1 - 1.6e-18 67.0 0.0 2.8e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 GAM41193.1 - 7.1e-18 65.2 0.0 1.9e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 GAM41193.1 - 7.6e-15 55.0 0.5 1.8e-14 53.8 0.5 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 GAM41193.1 - 1.1e-13 51.4 0.0 4.2e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Acyl_transf_1 PF00698.21 GAM41193.1 - 2.8e-13 50.1 0.0 3.7e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain Abhydrolase_3 PF07859.13 GAM41193.1 - 9e-12 45.3 0.0 1.3e-09 38.3 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_25 PF13649.6 GAM41193.1 - 5.9e-10 39.7 0.0 1.7e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 GAM41193.1 - 8.9e-10 38.7 0.2 2.5e-06 27.4 0.1 3.6 3 1 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_11 PF08241.12 GAM41193.1 - 4.2e-09 36.9 0.0 1e-08 35.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAM41193.1 - 4.6e-09 36.7 0.1 1.3e-08 35.3 0.1 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 GAM41193.1 - 1.6e-08 34.5 0.0 1.2e-07 31.7 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Peptidase_S9 PF00326.21 GAM41193.1 - 4.2e-06 26.4 0.0 0.013 15.0 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 GAM41193.1 - 3.8e-05 22.8 0.0 6.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Thiolase_N PF00108.23 GAM41193.1 - 0.00029 20.3 0.0 0.0006 19.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_33 PF10017.9 GAM41193.1 - 0.00071 18.8 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_16 PF10294.9 GAM41193.1 - 0.00084 19.1 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Abhydrolase_6 PF12697.7 GAM41193.1 - 0.0047 17.6 0.5 0.065 13.8 0.3 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ubie_methyltran PF01209.18 GAM41193.1 - 0.02 14.2 0.0 0.048 13.0 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 GAM41193.1 - 0.03 13.9 0.0 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Thioesterase PF00975.20 GAM41193.1 - 0.088 12.9 0.1 20 5.2 0.0 2.9 3 0 0 3 3 3 0 Thioesterase domain DLH PF01738.18 GAM41193.1 - 0.15 11.6 0.0 7.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family MFS_1 PF07690.16 GAM41194.1 - 3e-08 33.0 14.2 3e-08 33.0 14.2 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM41194.1 - 7.2e-05 21.4 10.9 0.00013 20.5 10.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HABP4_PAI-RBP1 PF04774.15 GAM41195.1 - 0.017 16.0 1.1 0.025 15.4 1.1 1.3 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family ALAD PF00490.21 GAM41196.1 - 3.7e-121 404.2 0.0 4.4e-121 403.9 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Mac_assoc PF16628.5 GAM41197.1 - 2.5e-84 282.1 10.2 2.5e-84 282.1 10.2 2.2 2 1 1 3 3 3 1 Unstructured region on maltose acetyltransferase Mac PF12464.8 GAM41197.1 - 2.1e-12 47.1 0.0 6.4e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 GAM41197.1 - 2.2e-10 40.1 4.9 1.1e-07 31.5 0.0 3.4 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.18 GAM41197.1 - 6.9e-10 38.9 8.5 1.5e-09 37.8 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep PF00132.24 GAM41197.1 - 1.5e-08 34.0 5.6 0.00033 20.3 0.1 3.7 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) CRM1_C PF08767.11 GAM41199.1 - 2.4e-138 460.7 8.6 2.4e-138 460.7 8.6 3.0 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 GAM41199.1 - 4.2e-42 143.7 10.7 4.6e-41 140.4 6.4 3.9 3 1 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 GAM41199.1 - 9.8e-34 114.8 4.7 2e-33 113.9 3.6 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 GAM41199.1 - 3.3e-29 100.7 0.6 3.3e-29 100.7 0.6 2.7 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 GAM41199.1 - 2.5e-20 71.7 1.8 5.5e-20 70.6 1.8 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 GAM41199.1 - 4.8e-12 45.6 0.1 2.1e-11 43.5 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 GAM41199.1 - 0.017 15.1 5.5 0.09 12.7 0.0 4.2 5 1 1 6 6 6 0 Domain of unknown function (DUF3385) HD_assoc PF13286.6 GAM41199.1 - 0.11 13.0 2.3 25 5.5 0.2 3.9 4 0 0 4 4 4 0 Phosphohydrolase-associated domain AF-4 PF05110.13 GAM41200.1 - 0.018 13.2 16.2 0.019 13.1 16.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SURF2 PF05477.11 GAM41200.1 - 0.031 14.0 7.1 0.041 13.6 7.1 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 GAM41200.1 - 0.43 8.8 15.5 0.47 8.7 15.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GAM41200.1 - 1 7.4 8.7 1.3 7.0 8.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi NTPase_P4 PF11602.8 GAM41200.1 - 1.4 8.0 4.8 1.8 7.7 4.8 1.1 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 SR-25 PF10500.9 GAM41200.1 - 2.8 7.5 24.3 0.2 11.2 15.2 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Zip PF02535.22 GAM41200.1 - 7.9 5.6 8.5 10 5.2 8.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Shugoshin_N PF07558.11 GAM41201.1 - 6.4e-17 61.1 7.0 1.5e-16 59.9 3.4 2.5 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 GAM41201.1 - 1.5e-10 40.6 4.6 1.5e-10 40.6 4.6 2.6 2 0 0 2 2 2 1 Shugoshin C terminus bZIP_2 PF07716.15 GAM41201.1 - 0.01 15.9 0.5 0.056 13.5 0.5 2.3 1 0 0 1 1 1 0 Basic region leucine zipper Prok-TraM PF09228.10 GAM41201.1 - 0.017 15.5 0.3 0.056 13.8 0.3 2.0 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM CCDC85 PF10226.9 GAM41201.1 - 0.027 14.1 0.5 0.077 12.7 0.5 1.8 1 0 0 1 1 1 0 CCDC85 family HALZ PF02183.18 GAM41201.1 - 0.51 10.6 3.9 1.6 9.0 1.1 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 GAM41201.1 - 1 9.2 3.7 1.6 8.6 1.5 2.5 1 1 1 2 2 2 0 Septum formation initiator CtIP_N PF10482.9 GAM41201.1 - 1.2 9.1 7.3 2.8 8.0 0.8 3.0 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Mod_r PF07200.13 GAM41201.1 - 7.8 6.6 9.5 0.58 10.3 3.4 2.2 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DASH_Dad2 PF08654.10 GAM41202.1 - 1.6e-26 92.6 6.1 5.2e-26 91.0 6.1 1.7 1 1 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.22 GAM41202.1 - 0.0067 16.6 0.5 0.011 15.9 0.5 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain PAXX PF15384.6 GAM41202.1 - 0.019 14.6 1.2 0.022 14.4 1.2 1.2 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 CENP-F_leu_zip PF10473.9 GAM41202.1 - 0.037 14.1 1.7 0.044 13.8 1.7 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 GAM41202.1 - 0.043 13.9 4.2 0.051 13.6 4.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Duo1 PF08651.10 GAM41202.1 - 0.044 13.6 0.9 0.084 12.7 0.9 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 ABC_tran_CTD PF16326.5 GAM41202.1 - 0.073 13.3 6.1 0.6 10.4 0.8 2.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain NPV_P10 PF05531.12 GAM41202.1 - 0.086 13.3 2.1 0.72 10.4 0.8 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TEX13 PF15186.6 GAM41202.1 - 0.18 11.5 2.9 0.21 11.3 2.9 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DAO PF01266.24 GAM41203.1 - 2.1e-50 172.3 0.1 3.2e-50 171.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 GAM41203.1 - 2.1e-44 150.4 0.1 3.8e-44 149.6 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 GAM41203.1 - 8.9e-09 34.9 0.1 1.8e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAM41203.1 - 0.00039 19.9 0.5 0.00077 18.9 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM41203.1 - 0.0012 18.2 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM41203.1 - 0.0067 16.6 0.3 0.025 14.8 0.4 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 GAM41203.1 - 0.017 15.0 0.3 0.033 14.1 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 GAM41203.1 - 0.037 13.1 0.2 0.1 11.7 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 GAM41203.1 - 0.037 12.7 0.9 0.085 11.5 0.7 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 GAM41203.1 - 0.073 13.6 0.7 0.18 12.4 0.7 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM41203.1 - 0.11 11.7 0.4 0.23 10.6 0.3 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NFACT-R_1 PF05670.13 GAM41204.1 - 2.4e-31 108.6 0.9 1.1e-30 106.4 0.1 2.7 2 0 0 2 2 2 1 NFACT protein RNA binding domain GRAB PF10375.9 GAM41204.1 - 9.1e-09 34.9 0.1 2.5e-08 33.5 0.1 1.8 1 0 0 1 1 1 1 GRIP-related Arf-binding domain TBCC PF07986.12 GAM41204.1 - 0.027 14.2 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 Tubulin binding cofactor C Baculo_PEP_C PF04513.12 GAM41204.1 - 0.41 10.7 29.3 3 7.9 4.1 4.4 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 GAM41204.1 - 0.65 10.3 28.1 0.47 10.7 0.5 4.9 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 GAM41204.1 - 2.6 8.5 34.0 1.9 8.9 1.0 6.8 4 1 2 6 6 6 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 GAM41204.1 - 6.2 6.9 30.2 4.9 7.2 8.6 4.2 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Guanylate_kin PF00625.21 GAM41205.1 - 2e-65 219.9 0.0 2.5e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 GAM41205.1 - 1.9e-06 28.4 0.5 6.8e-06 26.6 0.5 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 GAM41205.1 - 9.8e-06 25.8 0.2 6.1e-05 23.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAM41205.1 - 4e-05 24.2 0.9 0.00015 22.3 0.5 2.1 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 GAM41205.1 - 0.00023 21.5 0.0 0.00057 20.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 GAM41205.1 - 0.00087 19.8 0.0 0.0013 19.2 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 GAM41205.1 - 0.0012 19.1 0.1 0.0025 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAM41205.1 - 0.0019 17.3 0.0 0.0035 16.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 GAM41205.1 - 0.0019 18.1 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_7 PF12775.7 GAM41205.1 - 0.0019 17.7 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 GAM41205.1 - 0.0027 17.8 0.0 0.0046 17.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 GAM41205.1 - 0.0029 17.4 0.2 0.039 13.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAM41205.1 - 0.0034 17.8 0.0 0.0064 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase DUF2075 PF09848.9 GAM41205.1 - 0.0078 15.5 0.0 0.14 11.4 0.0 2.0 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 GAM41205.1 - 0.0083 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_30 PF13604.6 GAM41205.1 - 0.0087 15.8 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAM41205.1 - 0.0092 16.4 0.1 0.034 14.6 0.0 1.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GAM41205.1 - 0.0099 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 GAM41205.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAM41205.1 - 0.019 14.7 0.1 0.035 13.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 GAM41205.1 - 0.023 14.6 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 GAM41205.1 - 0.04 13.9 0.1 0.2 11.6 0.0 2.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 GAM41205.1 - 0.043 13.7 0.0 0.051 13.5 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 GAM41205.1 - 0.091 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 GAM41205.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 GAM41205.1 - 0.18 11.7 0.3 1.7 8.5 0.0 2.3 2 1 0 2 2 2 0 Deoxynucleoside kinase Septin PF00735.18 GAM41206.1 - 1.6e-113 378.7 1.5 1.9e-113 378.5 1.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAM41206.1 - 3.7e-08 33.4 0.0 8.2e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 GAM41206.1 - 1e-05 24.9 0.0 1.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 GAM41206.1 - 8.6e-05 22.5 0.8 0.00046 20.1 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 GAM41206.1 - 0.00011 21.8 1.5 0.023 14.3 0.1 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 GAM41206.1 - 0.00027 21.0 0.4 0.81 9.7 0.2 2.5 1 1 1 2 2 2 2 Dynamin family AAA_7 PF12775.7 GAM41206.1 - 0.00075 19.1 0.1 0.0042 16.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 GAM41206.1 - 0.0023 17.2 0.1 0.0042 16.3 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 GAM41206.1 - 0.006 17.0 0.0 0.013 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 GAM41206.1 - 0.0091 16.5 0.5 0.019 15.5 0.2 1.6 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 GAM41206.1 - 0.014 15.7 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 GAM41206.1 - 0.02 14.3 0.1 0.33 10.3 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Roc PF08477.13 GAM41206.1 - 0.04 14.1 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAM41206.1 - 0.047 12.9 0.8 0.32 10.1 0.2 1.9 1 1 1 2 2 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 GAM41206.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 GAM41206.1 - 0.15 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L32p PF01783.23 GAM41207.1 - 7.7e-14 51.7 3.6 1.2e-13 51.1 3.6 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family WD40 PF00400.32 GAM41208.1 - 1.3e-20 73.3 13.1 9.2e-08 32.6 0.7 6.6 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM41208.1 - 6.7e-16 58.4 0.9 0.00018 21.7 0.0 4.4 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM41208.1 - 8.6e-05 22.5 0.1 0.038 13.9 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 GAM41208.1 - 0.00057 19.3 0.0 0.57 9.5 0.0 2.4 2 1 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 GAM41208.1 - 0.0075 15.0 0.0 1.3 7.6 0.0 2.2 1 1 0 2 2 2 2 Nucleoporin Nup120/160 VID27 PF08553.10 GAM41208.1 - 0.016 14.3 0.0 0.074 12.1 0.0 2.0 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain Cytochrom_D1 PF02239.16 GAM41208.1 - 0.066 11.7 0.1 0.72 8.3 0.1 2.0 1 1 0 1 1 1 0 Cytochrome D1 heme domain DUF1513 PF07433.11 GAM41208.1 - 0.072 12.2 0.1 6.5 5.7 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1513) Asp_decarbox PF02261.16 GAM41208.1 - 0.13 12.2 0.0 5.2 7.0 0.0 2.7 1 1 1 2 2 2 0 Aspartate decarboxylase Coatomer_WDAD PF04053.14 GAM41208.1 - 0.18 10.8 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region Spindle_Spc25 PF08234.12 GAM41209.1 - 3.3e-21 75.3 0.0 1e-20 73.7 0.0 1.9 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Filament PF00038.21 GAM41209.1 - 0.0028 17.3 10.4 0.006 16.2 10.4 1.5 1 0 0 1 1 1 1 Intermediate filament protein Polysacc_deac_1 PF01522.21 GAM41209.1 - 0.03 14.2 0.9 0.054 13.4 0.9 1.4 1 0 0 1 1 1 0 Polysaccharide deacetylase DUF4407 PF14362.6 GAM41209.1 - 0.093 12.1 10.7 0.15 11.4 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.11 GAM41209.1 - 0.67 8.4 11.7 0.89 8.0 11.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Calpain_III PF01067.22 GAM41209.1 - 1.1 9.5 3.9 1.8 8.8 3.9 1.3 1 0 0 1 1 1 0 Calpain large subunit, domain III Atg14 PF10186.9 GAM41209.1 - 1.5 7.9 10.4 2.4 7.2 10.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BRE1 PF08647.11 GAM41209.1 - 2.1 8.5 16.2 0.46 10.6 12.0 2.0 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase OmpH PF03938.14 GAM41209.1 - 5.5 7.3 16.3 3.7 7.9 14.3 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Rrn6 PF10214.9 GAM41210.1 - 2.8e-196 654.8 2.1 3.1e-196 654.6 2.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor HMA PF00403.26 GAM41211.1 - 1.9e-17 63.5 0.7 2.2e-17 63.3 0.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 GAM41211.1 - 0.07 13.5 0.1 0.18 12.2 0.0 1.7 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain GnsAB_toxin PF08178.11 GAM41211.1 - 0.15 12.0 0.7 2.2 8.2 0.2 2.1 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system DUF2293 PF10056.9 GAM41212.1 - 7e-30 103.1 0.4 1.4e-29 102.1 0.4 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) zinc_ribbon_6 PF14599.6 GAM41213.1 - 5.6e-21 74.3 1.5 5.6e-21 74.3 1.5 2.2 2 0 0 2 2 2 1 Zinc-ribbon zf-CHY PF05495.12 GAM41213.1 - 1.6e-18 66.9 15.5 1.6e-18 66.9 15.5 2.4 2 0 0 2 2 2 1 CHY zinc finger TF_Zn_Ribbon PF08271.12 GAM41213.1 - 0.82 9.2 7.1 2.2 7.9 0.5 3.1 2 1 0 2 2 2 0 TFIIB zinc-binding Cnn_1N PF07989.11 GAM41214.1 - 1.9e-24 85.6 4.0 1.9e-24 85.6 4.0 15.7 5 3 9 15 15 15 1 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 GAM41214.1 - 1.8e-20 73.3 6.3 2.5e-20 72.8 2.1 3.8 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Fez1 PF06818.15 GAM41214.1 - 0.00014 22.4 173.2 0.1 13.0 29.1 8.3 2 1 7 9 9 9 5 Fez1 TMF_TATA_bd PF12325.8 GAM41214.1 - 0.0054 16.9 11.7 0.0054 16.9 11.7 12.7 3 2 5 12 12 12 1 TATA element modulatory factor 1 TATA binding IL10 PF00726.17 GAM41214.1 - 0.037 13.5 6.2 0.69 9.4 0.1 3.7 3 0 0 3 3 3 0 Interleukin 10 TAF8_C PF10406.9 GAM41214.1 - 0.17 12.5 2.5 3.4 8.3 2.5 3.6 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term Spc7 PF08317.11 GAM41214.1 - 0.29 10.0 183.0 0.2 10.5 20.5 8.9 1 1 8 9 9 9 0 Spc7 kinetochore protein IF3_C PF00707.22 GAM41214.1 - 2.9 7.9 8.5 1 9.4 0.1 4.2 4 0 0 4 4 4 0 Translation initiation factor IF-3, C-terminal domain DUF150 PF02576.17 GAM41214.1 - 5 7.6 6.0 1.1 9.7 0.8 2.8 2 1 0 2 2 2 0 RimP N-terminal domain SGT1 PF07093.11 GAM41215.1 - 4.4e-97 325.9 18.1 2.5e-87 293.7 0.0 2.0 1 1 1 2 2 2 2 SGT1 protein DUF1980 PF09323.10 GAM41215.1 - 0.075 12.9 0.4 0.13 12.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) AMMECR1 PF01871.17 GAM41216.1 - 1.5e-27 96.2 0.0 7.9e-16 58.1 0.0 2.6 2 1 1 3 3 3 2 AMMECR1 AbLIM_anchor PF16182.5 GAM41216.1 - 0.0049 16.7 2.2 0.0049 16.7 2.2 1.6 2 0 0 2 2 2 1 Putative adherens-junction anchoring region of AbLIM ALS2CR11 PF15729.5 GAM41216.1 - 0.13 11.4 1.4 0.17 11.0 1.4 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 PI3K_1B_p101 PF10486.9 GAM41216.1 - 2.8 5.6 7.7 3.8 5.2 7.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pkinase PF00069.25 GAM41217.1 - 5.7e-75 252.1 0.0 7.5e-75 251.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM41217.1 - 4.3e-30 104.9 0.0 5.9e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM41217.1 - 6.5e-08 32.2 0.0 9.4e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAM41217.1 - 9e-05 21.4 0.0 0.00018 20.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAM41217.1 - 0.00015 21.2 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM41217.1 - 0.00026 21.0 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family SEN1_N PF12726.7 GAM41217.1 - 0.081 11.1 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 SEN1 N terminal DUF1744 PF08490.12 GAM41218.1 - 2.8e-151 503.7 0.1 4.1e-151 503.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 GAM41218.1 - 4.2e-82 276.0 0.2 6.1e-81 272.2 0.1 2.3 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 GAM41218.1 - 4.7e-14 52.0 0.0 2.3e-11 43.1 0.0 3.4 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 GAM41218.1 - 3.7e-08 33.3 0.1 9.8e-08 31.9 0.1 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 GAM41218.1 - 8e-05 22.7 0.0 0.00036 20.6 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily DUF3767 PF12597.8 GAM41219.1 - 1.3e-36 124.5 0.0 2e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Nop53 PF07767.11 GAM41219.1 - 2.8 7.3 10.0 1.8 7.9 0.2 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Nop PF01798.18 GAM41221.1 - 2.3e-88 295.6 0.0 2.3e-88 295.6 0.0 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 GAM41221.1 - 2.1e-14 53.6 0.2 2.1e-14 53.6 0.2 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 GAM41221.1 - 0.046 13.8 33.2 0.072 13.2 33.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.12 GAM41221.1 - 2.6 8.3 11.9 5 7.3 11.9 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3408 PF11888.8 GAM41221.1 - 3.3 7.9 15.9 38 4.4 16.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) RP-C_C PF11800.8 GAM41221.1 - 4.6 7.3 7.1 43 4.1 0.0 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region EIIBC-GUT_N PF03612.14 GAM41221.1 - 6.5 6.5 7.6 12 5.6 7.6 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CobT PF06213.12 GAM41221.1 - 8.1 5.7 20.7 1.6 8.1 17.0 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Cpn60_TCP1 PF00118.24 GAM41222.1 - 1.1e-163 545.4 1.2 1.2e-163 545.2 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3888 PF13027.6 GAM41222.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) Herpes_UL6 PF01763.16 GAM41222.1 - 0.12 10.8 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like MOZ_SAS PF01853.18 GAM41223.1 - 2.1e-63 213.2 0.0 3.6e-63 212.5 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GAM41223.1 - 1e-16 60.2 0.4 2e-16 59.4 0.4 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain IF2_N PF04760.15 GAM41223.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region RRM_1 PF00076.22 GAM41224.1 - 9.9e-11 41.3 0.0 5.2e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1664 PF07889.12 GAM41224.1 - 0.13 12.3 0.1 0.33 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Trimer_CC PF08954.11 GAM41224.1 - 0.72 9.5 4.0 3.1 7.4 0.1 3.6 3 0 0 3 3 3 0 Trimerisation motif Muted PF14942.6 GAM41224.1 - 1.1 9.6 4.4 4.7 7.6 0.1 2.7 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein tRNA-synt_2 PF00152.20 GAM41225.1 - 2.4e-67 227.3 0.0 6.9e-54 183.0 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAM41225.1 - 0.0028 17.6 0.0 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Sec23_trunk PF04811.15 GAM41227.1 - 1.4e-47 162.4 0.0 2.7e-47 161.4 0.0 1.5 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAM41227.1 - 1.7e-25 88.8 0.0 5.6e-25 87.1 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAM41227.1 - 1.6e-17 64.0 0.0 3.5e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAM41227.1 - 2.4e-16 59.5 6.2 6e-16 58.2 6.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAM41227.1 - 9e-07 28.7 0.0 2.2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat AA_permease_2 PF13520.6 GAM41228.1 - 6.5e-63 213.0 47.8 7.7e-63 212.8 47.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM41228.1 - 1.5e-19 70.0 41.4 2e-19 69.6 41.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2721 PF11026.8 GAM41228.1 - 0.6 10.0 0.0 0.6 10.0 0.0 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF2721) Peptidase_M56 PF05569.11 GAM41228.1 - 1.7 7.8 5.6 0.51 9.5 1.9 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 FMN_red PF03358.15 GAM41229.1 - 1.1e-07 31.7 0.0 1.5e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAM41229.1 - 0.00015 21.5 0.0 0.0002 21.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Gti1_Pac2 PF09729.9 GAM41230.1 - 2.9e-45 154.6 0.5 8.7e-38 130.2 0.1 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Lactamase_B_6 PF16661.5 GAM41232.1 - 1.9e-64 216.7 0.0 4.4e-64 215.5 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 GAM41232.1 - 6e-47 160.0 0.1 6e-47 160.0 0.1 2.1 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 GAM41232.1 - 4.8e-15 55.8 0.0 1.9e-14 53.9 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 GAM41232.1 - 2e-11 43.7 0.0 5.4e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 GAM41232.1 - 0.037 14.0 0.4 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily CDH-cyt PF16010.5 GAM41234.1 - 6.8e-17 61.7 0.3 1.1e-16 61.1 0.3 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase MFS_1 PF07690.16 GAM41235.1 - 2.4e-33 115.5 58.7 2.1e-32 112.4 40.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 GAM41236.1 - 1.2e-68 231.7 0.1 1.7e-68 231.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM41236.1 - 2.4e-09 37.2 10.4 3.8e-09 36.5 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FinO_N PF12602.8 GAM41236.1 - 0.11 12.8 0.4 0.28 11.5 0.4 1.6 1 0 0 1 1 1 0 Fertility inhibition protein N terminal AT_hook PF02178.19 GAM41236.1 - 0.43 10.6 6.8 1.2 9.2 6.8 1.9 1 0 0 1 1 1 0 AT hook motif Frag1 PF10277.9 GAM41237.1 - 1.2e-38 132.8 8.8 1.2e-38 132.8 8.8 2.8 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family U3_assoc_6 PF08640.11 GAM41238.1 - 4.9e-28 97.0 2.5 5.6e-28 96.8 0.8 1.9 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 GAM41238.1 - 8e-07 29.4 1.7 0.0016 19.1 0.2 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.10 GAM41238.1 - 0.0043 16.2 0.0 0.0072 15.5 0.0 1.4 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference Suf PF05843.14 GAM41238.1 - 0.042 13.8 4.6 0.068 13.1 0.6 2.8 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) DUF1351 PF07083.11 GAM41238.1 - 0.043 13.6 0.3 0.11 12.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Leo1 PF04004.13 GAM41240.1 - 2.4e-27 95.8 0.0 1.2e-26 93.5 0.0 2.1 1 1 0 1 1 1 1 Leo1-like protein Caf4 PF11615.8 GAM41240.1 - 0.057 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 CCR4-associated factor 4 Mob1_phocein PF03637.17 GAM41241.1 - 1e-50 172.1 0.0 1.4e-49 168.4 0.0 2.4 2 1 0 2 2 2 1 Mob1/phocein family Shugoshin_N PF07558.11 GAM41242.1 - 0.0013 18.6 0.6 0.0034 17.2 0.6 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Thioredoxin_7 PF13899.6 GAM41242.1 - 0.14 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like DUF4618 PF15397.6 GAM41242.1 - 0.18 11.2 1.8 11 5.3 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) Rhomboid PF01694.22 GAM41243.1 - 6.8e-24 84.6 7.5 6.8e-24 84.6 7.5 1.6 2 0 0 2 2 2 1 Rhomboid family Ribosomal_L6 PF00347.23 GAM41243.1 - 1.2e-20 74.0 2.6 1.1e-09 38.8 0.2 2.6 2 0 0 2 2 2 2 Ribosomal protein L6 Myb_DNA-binding PF00249.31 GAM41243.1 - 0.072 13.3 0.4 0.16 12.2 0.4 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF2157 PF09925.9 GAM41243.1 - 0.71 9.7 3.9 2 8.2 3.9 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF3336 PF11815.8 GAM41244.1 - 5.1e-33 113.7 0.0 9.6e-33 112.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAM41244.1 - 5.4e-17 62.7 0.1 1.2e-16 61.5 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase PhoD PF09423.10 GAM41244.1 - 1.3e-05 24.4 0.5 0.00095 18.3 0.2 2.4 2 1 0 2 2 2 2 PhoD-like phosphatase Fungal_trans_2 PF11951.8 GAM41245.1 - 7.3e-41 140.3 1.7 8.9e-41 140.0 1.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM41245.1 - 0.00011 22.2 10.4 0.0003 20.8 10.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 GAM41246.1 - 2.8e-48 164.8 48.7 3.5e-48 164.5 48.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM41246.1 - 1e-24 87.0 44.3 1.4e-24 86.6 44.3 1.0 1 0 0 1 1 1 1 Amino acid permease DUF267 PF03268.14 GAM41246.1 - 0.77 8.6 7.5 1.3 7.9 1.0 2.5 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF267 Phenol_monoox PF04663.12 GAM41246.1 - 4.1 7.6 6.9 9.9 6.4 0.0 3.3 3 0 0 3 3 3 0 Phenol hydroxylase conserved region Glutaredoxin PF00462.24 GAM41247.1 - 1.2e-14 54.3 0.0 2.8e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 GAM41247.1 - 0.041 13.7 0.1 0.041 13.7 0.1 2.2 1 1 1 2 2 2 0 F plasmid transfer operon protein Conotoxin PF02950.17 GAM41247.1 - 0.26 12.3 1.2 2.1 9.4 0.0 2.7 2 1 1 3 3 3 0 Conotoxin DUF4551 PF15087.6 GAM41247.1 - 0.27 10.0 8.4 0.33 9.7 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PXA PF02194.15 GAM41248.1 - 3.9e-49 167.1 0.7 1.7e-48 165.0 0.6 2.2 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 GAM41248.1 - 1.5e-25 90.0 0.2 1.9e-24 86.4 0.0 3.0 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 GAM41248.1 - 1.2e-19 70.4 1.2 2.7e-19 69.2 0.4 2.0 2 0 0 2 2 2 1 PX domain RGS PF00615.19 GAM41248.1 - 5.3e-12 46.0 0.1 2.2e-11 44.0 0.1 2.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain LRR19-TM PF15176.6 GAM41248.1 - 0.37 10.8 2.1 53 3.9 0.9 3.2 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain PEMT PF04191.13 GAM41249.1 - 5.6e-34 116.7 5.9 4e-33 114.0 3.3 2.3 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1223 PF06764.11 GAM41249.1 - 0.045 13.8 0.0 0.061 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) EPV_E5 PF08135.11 GAM41249.1 - 0.075 13.4 1.4 0.21 12.0 1.4 1.7 1 0 0 1 1 1 0 Major transforming protein E5 family Gryzun PF07919.12 GAM41250.1 - 2.7e-230 766.2 0.0 3.8e-230 765.7 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 GAM41250.1 - 4.1e-92 308.4 7.6 1.1e-82 277.6 7.0 2.3 2 0 0 2 2 2 2 Foie gras liver health family 1 RXT2_N PF08595.11 GAM41250.1 - 2.6e-28 99.0 0.1 2.6e-28 99.0 0.1 2.3 2 0 0 2 2 2 1 RXT2-like, N-terminal DUF4625 PF15418.6 GAM41251.1 - 0.27 11.5 8.1 0.73 10.1 4.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4625) DUF3328 PF11807.8 GAM41252.1 - 7.9e-48 163.1 0.0 9.8e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RIC3 PF15361.6 GAM41252.1 - 0.07 13.5 0.0 0.095 13.1 0.0 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF3961 PF13106.6 GAM41252.1 - 1.4 8.7 3.8 2.4 7.8 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Ank_3 PF13606.6 GAM41253.1 - 1.9e-20 70.8 0.1 2.8e-07 30.3 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 GAM41253.1 - 2.6e-20 71.9 1.0 2.4e-06 27.7 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 GAM41253.1 - 1.3e-19 70.6 0.0 5e-11 43.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM41253.1 - 1.2e-17 63.7 0.0 8.6e-10 38.7 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM41253.1 - 1.8e-17 63.4 0.0 6.9e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PEGA PF08308.11 GAM41253.1 - 0.0035 17.2 0.0 6.1 6.8 0.0 3.3 3 0 0 3 3 3 2 PEGA domain RNA_polI_A34 PF08208.11 GAM41254.1 - 4.5e-40 137.9 35.9 4.3e-38 131.5 35.9 2.0 1 1 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Endostatin PF06482.11 GAM41254.1 - 0.68 9.3 9.4 0.98 8.8 9.4 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CLP1_P PF16575.5 GAM41256.1 - 1e-25 90.6 0.0 1.8e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 GAM41256.1 - 0.024 15.0 0.1 0.31 11.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 GAM41256.1 - 0.047 14.2 0.2 0.22 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAM41256.1 - 0.052 13.7 0.5 0.45 10.7 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAM41256.1 - 0.07 13.4 0.2 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAM41256.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAM41256.1 - 0.18 11.6 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fungal_trans PF04082.18 GAM41257.1 - 3.9e-12 45.8 0.0 9.1e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cnn_1N PF07989.11 GAM41257.1 - 0.1 12.8 0.1 0.31 11.2 0.1 1.8 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 MFS_1 PF07690.16 GAM41258.1 - 2.3e-35 122.2 78.8 4.2e-27 95.0 47.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 GAM41258.1 - 2.6e-05 23.7 28.2 3.5e-05 23.3 28.2 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 GAM41258.1 - 0.00046 19.2 12.3 0.00046 19.2 12.3 3.7 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 GAM41258.1 - 0.003 16.5 28.7 0.012 14.5 5.6 3.2 2 2 1 3 3 3 3 MFS_1 like family PDCD2_C PF04194.13 GAM41259.1 - 9e-42 143.1 0.0 2.6e-40 138.4 0.0 2.2 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain zf-RING_7 PF02591.15 GAM41259.1 - 0.058 13.6 0.3 0.15 12.3 0.3 1.7 1 0 0 1 1 1 0 C4-type zinc ribbon domain A2L_zn_ribbon PF08792.10 GAM41259.1 - 0.56 10.0 0.1 0.56 10.0 0.1 2.1 3 0 0 3 3 3 0 A2L zinc ribbon domain Prenylcys_lyase PF07156.14 GAM41260.1 - 1.7e-99 333.3 0.0 2.2e-99 333.0 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 GAM41260.1 - 3e-13 49.8 0.0 1.8e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAM41260.1 - 5e-12 45.9 0.0 9.5e-12 44.9 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 GAM41260.1 - 1.2e-06 28.4 0.0 3.4e-06 26.9 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM41260.1 - 0.0012 18.2 0.0 0.0089 15.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM41260.1 - 0.0012 18.1 0.3 0.0088 15.3 0.1 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 GAM41260.1 - 0.014 15.4 0.1 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAM41260.1 - 0.16 12.5 0.1 2.3 8.9 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HsbA PF12296.8 GAM41261.1 - 1.8e-18 67.1 19.2 1.8e-18 67.1 19.2 3.3 2 1 1 3 3 3 1 Hydrophobic surface binding protein A SKA1 PF07160.12 GAM41261.1 - 0.96 9.2 2.5 16 5.3 1.0 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 PPP4R2 PF09184.11 GAM41261.1 - 7.6 6.0 8.7 11 5.5 8.7 1.4 1 0 0 1 1 1 0 PPP4R2 Utp14 PF04615.13 GAM41261.1 - 8.4 4.8 6.6 9.7 4.6 6.6 1.1 1 0 0 1 1 1 0 Utp14 protein HsbA PF12296.8 GAM41262.1 - 2.2e-27 95.9 12.8 2.2e-27 95.9 12.8 1.6 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF285 PF03382.14 GAM41262.1 - 0.096 12.4 0.0 0.18 11.6 0.0 1.5 1 1 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 GRAM PF02893.20 GAM41263.1 - 3.9e-30 104.0 0.4 4.2e-21 75.0 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 GAM41263.1 - 3.8e-26 91.8 0.0 7.7e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 GAM41263.1 - 2.1e-15 57.1 2.0 7.7e-14 52.1 0.0 3.6 4 0 0 4 4 4 1 PH domain PH_3 PF14593.6 GAM41263.1 - 2.7e-05 24.2 0.0 5.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 GAM41263.1 - 5.4e-05 23.4 0.1 0.00017 21.8 0.1 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 GAM41263.1 - 0.00091 19.6 0.6 0.00091 19.6 0.6 3.1 3 1 0 3 3 3 1 Pleckstrin homology domain UDPGT PF00201.18 GAM41263.1 - 0.0021 16.9 0.0 0.0043 15.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_2 PF08458.10 GAM41263.1 - 0.097 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Plant pleckstrin homology-like region SHMT PF00464.19 GAM41264.1 - 5.3e-207 687.2 0.0 6.2e-207 686.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 GAM41264.1 - 0.0057 16.0 0.0 0.01 15.2 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 GAM41264.1 - 0.087 11.3 0.0 0.19 10.2 0.0 1.5 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Baculo_DNA_bind PF04786.12 GAM41264.1 - 0.22 10.9 0.0 0.46 9.8 0.0 1.4 1 0 0 1 1 1 0 ssDNA binding protein Med9 PF07544.13 GAM41265.1 - 2.3e-17 62.8 0.1 1e-16 60.8 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 GAM41265.1 - 0.096 12.9 10.4 0.26 11.5 10.4 1.8 1 1 0 1 1 1 0 Subunit 21 of Mediator complex iPGM_N PF06415.13 GAM41266.1 - 1.6e-74 250.0 0.0 2.2e-74 249.6 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 GAM41266.1 - 6e-71 238.7 0.0 6.9e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 GAM41266.1 - 7.9e-06 25.7 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAM41266.1 - 2.6e-05 23.8 0.0 4.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.20 GAM41266.1 - 0.085 11.8 0.2 0.26 10.2 0.0 1.7 2 0 0 2 2 2 0 Alkaline phosphatase Prefoldin_2 PF01920.20 GAM41267.1 - 3.8e-21 75.0 18.0 5.2e-21 74.6 18.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 GAM41267.1 - 0.00017 21.6 5.7 0.00025 21.0 5.7 1.3 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.11 GAM41267.1 - 0.00023 21.4 12.1 0.094 13.0 5.5 2.1 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 Spc7 PF08317.11 GAM41267.1 - 0.0032 16.4 17.3 0.0043 16.0 17.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Myosin_tail_1 PF01576.19 GAM41267.1 - 0.0041 15.0 11.9 0.0052 14.7 11.9 1.1 1 0 0 1 1 1 1 Myosin tail Prefoldin PF02996.17 GAM41267.1 - 0.0044 16.9 4.2 0.0044 16.9 4.2 2.6 2 1 0 3 3 3 1 Prefoldin subunit XhlA PF10779.9 GAM41267.1 - 0.0047 17.1 2.3 0.0047 17.1 2.3 1.9 2 1 0 2 2 2 1 Haemolysin XhlA Rh5 PF18515.1 GAM41267.1 - 0.016 14.5 3.6 0.022 14.0 3.6 1.4 1 0 0 1 1 1 0 Rh5 coiled-coil domain Spore_YpjB PF09577.10 GAM41267.1 - 0.033 14.0 5.4 0.045 13.6 5.4 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Rx_N PF18052.1 GAM41267.1 - 0.11 12.8 10.5 0.99 9.7 3.5 2.2 2 0 0 2 2 2 0 Rx N-terminal domain CENP-F_leu_zip PF10473.9 GAM41267.1 - 0.2 11.7 16.6 0.55 10.2 4.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HalX PF08663.10 GAM41267.1 - 0.25 11.7 8.8 3.8 7.9 0.1 2.9 2 1 0 2 2 2 0 HalX domain DivIC PF04977.15 GAM41267.1 - 0.29 10.9 24.1 0.31 10.8 3.0 3.3 2 1 1 3 3 3 0 Septum formation initiator NPV_P10 PF05531.12 GAM41267.1 - 0.4 11.2 12.4 0.86 10.1 1.5 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein PHM7_cyt PF14703.6 GAM41267.1 - 0.47 10.7 7.1 0.81 9.9 7.1 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter PspA_IM30 PF04012.12 GAM41267.1 - 0.49 9.9 19.1 1.9 8.0 9.6 2.0 1 1 1 2 2 2 0 PspA/IM30 family CALCOCO1 PF07888.11 GAM41267.1 - 0.51 9.1 15.8 24 3.7 15.8 2.0 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like YabA PF06156.13 GAM41267.1 - 0.58 10.8 12.2 3.4 8.4 1.7 2.1 2 0 0 2 2 2 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 GAM41267.1 - 0.73 10.1 16.8 2 8.7 3.2 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.6 GAM41267.1 - 0.92 9.9 18.2 3.3 8.1 5.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Taxilin PF09728.9 GAM41267.1 - 0.98 8.5 18.0 14 4.7 18.0 2.0 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Bcr-Abl_Oligo PF09036.10 GAM41267.1 - 1.3 9.0 5.8 0.59 10.2 1.0 2.1 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain End3 PF12761.7 GAM41267.1 - 1.3 9.1 11.6 1.8 8.7 11.6 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Csm1_N PF18504.1 GAM41267.1 - 1.6 9.1 19.3 1.3 9.4 1.7 3.9 2 2 2 4 4 4 0 Csm1 N-terminal domain Occludin_ELL PF07303.13 GAM41267.1 - 1.6 9.5 8.1 0.68 10.7 3.4 2.1 1 1 1 2 2 2 0 Occludin homology domain GrpE PF01025.19 GAM41267.1 - 2.1 8.0 12.8 5.3 6.7 3.9 2.2 2 0 0 2 2 2 0 GrpE OmpH PF03938.14 GAM41267.1 - 2.2 8.6 28.7 3.7 7.9 13.7 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 GAM41267.1 - 2.3 8.4 18.2 71 3.6 18.2 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ABC_tran_CTD PF16326.5 GAM41267.1 - 2.5 8.4 23.2 1.1 9.5 2.2 3.6 2 2 1 3 3 3 0 ABC transporter C-terminal domain APG6_N PF17675.1 GAM41267.1 - 3.1 8.3 23.1 3.3 8.3 5.9 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Rootletin PF15035.6 GAM41267.1 - 3.5 7.6 14.1 0.74 9.8 6.8 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.12 GAM41267.1 - 3.8 8.0 15.3 0.97 9.9 2.2 2.3 1 1 0 2 2 2 0 Centromere protein H (CENP-H) FlaC_arch PF05377.11 GAM41267.1 - 4.4 7.8 12.4 8.6 6.8 2.2 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) HAUS-augmin3 PF14932.6 GAM41267.1 - 4.9 6.7 18.7 4.5 6.8 9.6 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 MCU PF04678.13 GAM41267.1 - 6.4 6.8 8.2 42 4.2 8.2 1.9 1 1 0 1 1 1 0 Mitochondrial calcium uniporter BRE1 PF08647.11 GAM41267.1 - 6.6 6.9 18.3 0.68 10.0 3.6 2.4 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 GAM41267.1 - 8.4 6.5 12.2 6.2 6.9 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tcp11 PF05794.13 GAM41268.1 - 1.7e-113 380.1 1.0 1.7e-113 380.1 1.0 3.2 3 1 0 3 3 2 1 T-complex protein 11 AAA PF00004.29 GAM41268.1 - 2e-41 141.5 0.0 7.8e-41 139.6 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 GAM41268.1 - 1.4e-28 98.6 0.1 5.2e-28 96.8 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 GAM41268.1 - 2.6e-22 78.7 2.2 2.6e-22 78.7 2.2 3.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 GAM41268.1 - 8.6e-05 22.3 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAM41268.1 - 0.00022 21.2 0.1 0.0017 18.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GAM41268.1 - 0.00046 20.0 0.0 0.0014 18.4 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 GAM41268.1 - 0.00059 20.2 0.0 0.064 13.6 0.0 3.3 3 0 0 3 3 2 1 RNA helicase TIP49 PF06068.13 GAM41268.1 - 0.0007 18.9 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 GAM41268.1 - 0.0014 17.8 0.0 0.0061 15.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 GAM41268.1 - 0.002 18.3 4.5 0.0067 16.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GAM41268.1 - 0.0023 18.0 0.0 0.0067 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAM41268.1 - 0.003 17.8 0.1 0.37 11.1 0.0 3.3 1 1 1 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 GAM41268.1 - 0.0032 17.2 0.3 0.1 12.4 0.0 3.2 3 0 0 3 3 3 1 AAA+ lid domain AAA_2 PF07724.14 GAM41268.1 - 0.0063 16.6 0.0 0.04 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAM41268.1 - 0.0089 16.4 0.0 0.0089 16.4 0.0 4.9 3 2 1 4 4 3 1 AAA ATPase domain AAA_17 PF13207.6 GAM41268.1 - 0.0093 16.4 0.4 0.16 12.4 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM41268.1 - 0.014 15.9 2.1 0.059 13.9 0.0 3.3 4 0 0 4 4 2 0 AAA domain AAA_24 PF13479.6 GAM41268.1 - 0.032 13.9 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAM41268.1 - 0.035 13.5 0.0 0.13 11.6 0.0 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 GAM41268.1 - 0.13 12.4 0.0 0.62 10.2 0.0 2.2 2 0 0 2 2 1 0 Torsin AAA_7 PF12775.7 GAM41268.1 - 0.17 11.4 2.3 0.59 9.6 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region Vert_HS_TF PF06546.11 GAM41268.1 - 0.25 11.0 9.5 0.0086 15.8 3.3 1.6 2 0 0 2 2 1 0 Vertebrate heat shock transcription factor Herpes_capsid PF06112.11 GAM41268.1 - 0.86 9.7 9.1 3.5 7.7 9.1 2.0 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein WD40 PF00400.32 GAM41269.1 - 4.3e-30 103.3 25.1 4.8e-07 30.4 0.0 8.4 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM41269.1 - 7.7e-11 42.2 6.7 0.081 13.2 0.3 5.7 5 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain DUF2844 PF11005.8 GAM41269.1 - 0.22 11.6 2.4 0.62 10.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2844) SH3_9 PF14604.6 GAM41269.1 - 0.55 10.1 2.2 0.49 10.3 0.3 1.9 2 0 0 2 2 2 0 Variant SH3 domain DUF2796 PF10986.8 GAM41269.1 - 1.7 8.6 10.9 3 7.8 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Endosulfine PF04667.17 GAM41270.1 - 6.3e-29 99.9 0.0 1e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Peptidase_S10 PF00450.22 GAM41271.1 - 6.3e-118 394.8 0.0 7.9e-118 394.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RNA_Me_trans PF04252.13 GAM41271.1 - 1e-76 257.0 0.0 1.6e-76 256.4 0.0 1.3 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase ICE2 PF08426.10 GAM41272.1 - 3.1e-156 520.6 11.2 3.5e-156 520.4 11.2 1.0 1 0 0 1 1 1 1 ICE2 Yae1_N PF09811.9 GAM41273.1 - 8.8e-07 28.5 1.2 8.8e-07 28.5 1.2 1.7 2 0 0 2 2 2 1 Essential protein Yae1, N terminal WD40 PF00400.32 GAM41274.1 - 1.9e-18 66.4 2.0 0.0029 18.4 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM41274.1 - 1.4e-06 28.5 0.0 0.94 9.8 0.0 5.4 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM41274.1 - 0.0022 17.0 0.1 0.022 13.7 0.0 2.6 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAM41274.1 - 0.018 14.4 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Nup160 PF11715.8 GAM41274.1 - 0.033 12.8 0.1 0.18 10.4 0.1 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 FliO PF04347.13 GAM41274.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO AROS PF15684.5 GAM41275.1 - 0.00029 21.4 5.2 0.014 16.0 0.2 2.1 2 0 0 2 2 2 2 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 IPU_b_solenoid PF18783.1 GAM41275.1 - 0.017 15.2 0.3 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 Isopullulanase beta-solenoid repeat HHH_4 PF14490.6 GAM41275.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain Abhydrolase_1 PF00561.20 GAM41276.1 - 9.4e-10 38.6 0.0 5.5e-09 36.0 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM41276.1 - 2.1e-05 23.9 0.1 0.00021 20.6 0.0 2.5 3 0 0 3 3 3 1 Serine aminopeptidase, S33 DUF3237 PF11578.8 GAM41277.1 - 2.8e-28 98.6 0.1 3.2e-28 98.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) ABC2_membrane PF01061.24 GAM41278.1 - 1.4e-10 40.9 19.4 2e-10 40.5 18.7 1.6 1 1 0 1 1 1 1 ABC-2 type transporter Pox_int_trans PF05718.12 GAM41279.1 - 0.014 14.2 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus intermediate transcription factor Folliculin PF11704.8 GAM41280.1 - 2.2e-53 180.9 0.1 6.9e-53 179.3 0.0 1.9 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport DASH_Spc19 PF08287.11 GAM41281.1 - 1.3e-50 171.4 8.4 1.7e-50 171.0 8.4 1.2 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.12 GAM41281.1 - 0.0016 18.4 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Glyco_hydro_63 PF03200.16 GAM41281.1 - 0.062 12.1 0.0 0.078 11.7 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain DUF4824 PF16106.5 GAM41281.1 - 0.073 12.3 6.2 0.091 12.0 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4824) COG5 PF10392.9 GAM41281.1 - 2 8.6 8.8 13 6.0 0.5 3.1 1 1 3 4 4 4 0 Golgi transport complex subunit 5 Ribosomal_S14 PF00253.21 GAM41282.1 - 1.4e-21 76.0 2.0 6.8e-21 73.8 0.4 2.1 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Synaphin PF05835.12 GAM41282.1 - 0.32 11.3 1.2 0.44 10.8 1.2 1.2 1 0 0 1 1 1 0 Synaphin protein Amidohydro_1 PF01979.20 GAM41284.1 - 2.8e-27 95.9 0.0 2.3e-26 92.9 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM41284.1 - 1.1e-13 51.5 0.1 3e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Vma12 PF11712.8 GAM41285.1 - 4.5e-39 133.7 0.0 6.3e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Prefoldin PF02996.17 GAM41286.1 - 2.2e-24 85.7 1.8 3.7e-24 84.9 0.9 1.8 2 1 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 GAM41286.1 - 0.016 15.2 0.6 0.053 13.5 0.0 2.1 2 2 1 3 3 3 0 Prefoldin subunit Sulfolobus_pRN PF05584.11 GAM41286.1 - 0.11 12.5 0.1 0.26 11.4 0.0 1.6 2 0 0 2 2 2 0 Sulfolobus plasmid regulatory protein CSN8_PSD8_EIF3K PF10075.9 GAM41287.1 - 1.1e-48 164.9 0.0 1.3e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Rsm22 PF09243.10 GAM41288.1 - 1.9e-29 102.8 0.0 4.2e-28 98.4 0.0 3.0 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 GAM41288.1 - 0.0015 18.4 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM41288.1 - 0.11 13.2 0.2 0.47 11.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Rogdi_lz PF10259.9 GAM41289.1 - 6.6e-86 288.1 0.0 7.5e-86 287.9 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein SUR7 PF06687.12 GAM41290.1 - 7.2e-43 146.7 13.0 8.4e-43 146.5 13.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 GAM41290.1 - 0.0024 17.4 3.6 0.0044 16.5 3.6 1.4 1 0 0 1 1 1 1 Clc-like Amastin PF07344.11 GAM41290.1 - 0.035 13.9 10.4 0.04 13.8 8.3 2.0 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF3959 PF13105.6 GAM41290.1 - 0.28 10.7 2.6 0.49 9.9 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF373 PF04123.13 GAM41290.1 - 0.29 10.5 0.8 0.44 9.9 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) HSP70 PF00012.20 GAM41291.1 - 1.9e-80 270.8 2.5 1.9e-80 270.8 2.5 1.5 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 GAM41291.1 - 2e-08 33.4 0.3 3.4e-08 32.7 0.3 1.3 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 GAM41291.1 - 0.019 14.0 0.1 2.8 6.9 0.0 2.8 2 1 1 3 3 3 0 Type IV pilus assembly protein PilM; AAA_33 PF13671.6 GAM41291.1 - 0.14 12.3 0.2 0.28 11.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain DUF3221 PF11518.8 GAM41291.1 - 0.14 12.5 1.2 0.38 11.1 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) Vpu PF00558.19 GAM41291.1 - 0.21 11.4 1.6 0.42 10.4 1.6 1.4 1 0 0 1 1 1 0 Vpu protein KH_6 PF15985.5 GAM41292.1 - 2.5e-17 63.0 0.0 5.8e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 GAM41292.1 - 8.6e-07 28.8 0.4 2.3e-06 27.4 0.4 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain Myb_DNA-binding PF00249.31 GAM41293.1 - 3.3e-10 40.0 8.2 0.0001 22.4 0.1 3.8 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM41293.1 - 2.1e-09 37.5 6.7 2.7e-07 30.7 0.1 3.7 2 2 1 3 3 3 2 Myb-like DNA-binding domain Glyco_transf_24 PF18404.1 GAM41294.1 - 7.3e-149 494.5 1.6 1.2e-148 493.7 1.6 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 GAM41294.1 - 2.6e-65 220.9 0.0 1.8e-64 218.1 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 GAM41294.1 - 6.9e-50 169.6 0.0 2e-49 168.1 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 GAM41294.1 - 5.6e-44 150.6 0.0 5.5e-40 137.6 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 GAM41294.1 - 8.9e-44 148.7 0.0 1.1e-42 145.2 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 GAM41294.1 - 6.7e-39 132.4 0.0 1.5e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 GAM41294.1 - 0.00057 19.5 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Rpp20 PF12328.8 GAM41297.1 - 3.2e-48 163.2 11.9 2.5e-47 160.3 11.9 2.6 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 GAM41297.1 - 2.2e-17 62.6 0.1 3.8e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 Alba Glypican PF01153.19 GAM41297.1 - 0.072 11.9 4.6 0.1 11.4 4.6 1.2 1 0 0 1 1 1 0 Glypican DUF2786 PF10979.8 GAM41297.1 - 0.13 12.2 0.7 0.36 10.8 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) PRP38_assoc PF12871.7 GAM41297.1 - 0.19 12.3 16.4 0.43 11.2 16.4 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term CDC45 PF02724.14 GAM41297.1 - 0.48 8.7 9.0 0.64 8.2 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein FHA PF00498.26 GAM41298.1 - 8.5e-17 61.3 0.0 2.4e-16 59.8 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAM41298.1 - 0.00028 21.2 0.0 0.0011 19.3 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Hormone_1 PF00103.20 GAM41298.1 - 0.54 10.0 5.0 0.3 10.8 2.0 2.1 1 1 1 2 2 2 0 Somatotropin hormone family YabA PF06156.13 GAM41298.1 - 1 10.0 23.6 0.2 12.3 5.7 4.1 4 0 0 4 4 4 0 Initiation control protein YabA LMBR1 PF04791.16 GAM41298.1 - 9.5 5.0 12.5 0.95 8.3 1.2 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein Romo1 PF10247.9 GAM41299.1 - 1.1e-25 89.7 19.3 1.3e-25 89.5 19.3 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 GAM41299.1 - 0.058 13.8 4.8 0.066 13.6 4.8 1.1 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Hamartin PF04388.12 GAM41300.1 - 3 6.4 7.6 3.3 6.2 7.6 1.0 1 0 0 1 1 1 0 Hamartin protein GCIP PF13324.6 GAM41301.1 - 0.2 11.2 0.9 0.25 10.9 0.9 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Adaptin_N PF01602.20 GAM41303.1 - 1.2e-114 383.8 1.0 1.8e-114 383.2 1.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 GAM41303.1 - 2.1e-60 203.3 3.9 4.7e-60 202.1 3.9 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 GAM41303.1 - 4.4e-33 113.8 1.0 1.5e-32 112.1 0.1 2.5 3 0 0 3 3 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 GAM41303.1 - 1.6e-17 63.6 2.6 3.7e-12 46.5 0.1 5.4 4 1 2 6 6 6 1 HEAT repeats Cnd1 PF12717.7 GAM41303.1 - 2.3e-08 34.2 10.7 0.0024 17.9 0.2 4.8 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAM41303.1 - 0.0032 17.6 7.8 0.39 11.1 0.2 5.6 7 0 0 7 7 5 1 HEAT repeat HEAT_PBS PF03130.16 GAM41303.1 - 0.0049 17.4 0.6 4.4 8.3 0.0 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 GAM41303.1 - 0.013 16.0 0.7 0.063 13.8 0.7 2.2 1 0 0 1 1 1 0 HEAT-like repeat E2F_CC-MB PF16421.5 GAM41303.1 - 0.043 14.2 0.1 0.19 12.1 0.1 2.1 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain DUF2057 PF09829.9 GAM41303.1 - 0.064 13.4 1.6 0.17 12.1 1.6 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF5010 PF16402.5 GAM41303.1 - 0.13 11.0 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) UNC45-central PF11701.8 GAM41303.1 - 1.6 8.7 5.4 41 4.1 0.1 3.9 4 1 0 4 4 4 0 Myosin-binding striated muscle assembly central Phosducin PF02114.16 GAM41304.1 - 4.2e-14 52.1 0.0 5.2e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 GAM41304.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DASH_Dad3 PF08656.10 GAM41304.1 - 0.08 13.0 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad3 U3_assoc_6 PF08640.11 GAM41304.1 - 0.27 11.3 3.9 0.13 12.4 1.6 1.6 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Exog_C PF18026.1 GAM41304.1 - 6.3 6.9 6.4 48 4.1 0.1 2.4 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain Sugar_tr PF00083.24 GAM41305.1 - 8.5e-76 255.6 24.4 1e-75 255.3 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM41305.1 - 1.4e-29 103.1 42.2 2.5e-21 76.0 18.1 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Grg1 PF11034.8 GAM41306.1 - 0.26 11.5 3.3 0.83 9.9 0.4 2.3 2 0 0 2 2 2 0 Glucose-repressible protein Grg1 Mannosidase_ig PF17786.1 GAM41307.1 - 2.4e-18 66.5 2.0 1.6e-16 60.6 0.2 3.0 2 1 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 GAM41307.1 - 1.2e-13 51.7 0.2 4.3e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 GAM41307.1 - 0.00021 21.2 0.1 0.00085 19.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Fungal_trans PF04082.18 GAM41308.1 - 7.2e-09 35.1 0.0 1.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM41308.1 - 8e-07 29.1 13.6 1.6e-06 28.1 13.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP1 PF08601.10 GAM41309.1 - 1.7e-08 34.6 5.2 1.7e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 GAM41309.1 - 2.5e-08 33.9 13.8 4e-08 33.2 13.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAM41309.1 - 0.00091 19.3 16.7 0.001 19.1 15.5 1.7 1 1 1 2 2 2 1 Basic region leucine zipper SHE3 PF17078.5 GAM41309.1 - 0.0011 18.7 4.3 0.0016 18.2 4.3 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DivIC PF04977.15 GAM41309.1 - 0.012 15.4 3.1 0.022 14.5 3.1 1.4 1 0 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.19 GAM41309.1 - 0.012 13.6 3.0 0.014 13.3 3.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_Maf PF03131.17 GAM41309.1 - 0.014 15.9 13.8 0.023 15.2 13.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor YabA PF06156.13 GAM41309.1 - 0.024 15.3 1.2 0.042 14.5 1.2 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DUF4407 PF14362.6 GAM41309.1 - 0.031 13.6 4.9 0.059 12.7 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 GAM41309.1 - 0.033 14.6 0.7 0.059 13.8 0.7 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 GAM41309.1 - 0.06 13.6 4.5 0.094 12.9 4.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TSC22 PF01166.18 GAM41309.1 - 0.17 12.2 1.6 2.4 8.5 0.6 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family GvpL_GvpF PF06386.11 GAM41309.1 - 0.3 11.0 5.0 0.45 10.4 5.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF UPF0242 PF06785.11 GAM41309.1 - 0.42 10.7 4.6 0.58 10.2 4.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 GAM41309.1 - 0.75 10.3 8.0 0.24 11.9 4.9 1.7 1 1 1 2 2 2 0 Cell division protein ZapB APG6_N PF17675.1 GAM41309.1 - 1.2 9.6 9.4 1.8 9.1 9.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region GTA_holin_3TM PF11351.8 GAM41309.1 - 1.4 9.5 4.1 1.9 9.1 3.7 1.5 1 1 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Pkinase PF00069.25 GAM41310.1 - 4.5e-26 91.8 0.0 5.9e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM41310.1 - 6.1e-14 51.9 0.0 8.5e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM41310.1 - 4.1e-09 35.7 0.0 6.3e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAM41310.1 - 0.00017 21.6 0.0 0.0015 18.5 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kelch_4 PF13418.6 GAM41311.1 - 3.3e-32 110.2 11.6 1.1e-07 31.7 0.8 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM41311.1 - 2.5e-30 104.1 16.5 3.2e-07 30.5 0.2 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM41311.1 - 1.9e-29 100.9 8.3 2.3e-12 46.7 0.9 6.2 4 1 2 6 6 6 5 Kelch motif Kelch_1 PF01344.25 GAM41311.1 - 4.7e-29 99.7 1.2 5e-12 45.2 0.2 5.7 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 GAM41311.1 - 2.4e-24 84.9 10.9 8.6e-07 28.8 0.2 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 GAM41311.1 - 4.6e-21 73.9 9.6 1.4e-10 40.7 0.6 6.6 6 0 0 6 6 6 4 Kelch motif TPR_MLP1_2 PF07926.12 GAM41311.1 - 0.0022 18.1 22.3 0.0022 18.1 22.3 7.6 6 2 3 9 9 9 2 TPR/MLP1/MLP2-like protein Raptor_N PF14538.6 GAM41312.1 - 6.1e-66 220.9 0.0 1.2e-65 220.0 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 GAM41312.1 - 1e-05 26.2 9.3 0.4 11.6 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.6 GAM41312.1 - 0.0074 16.3 1.5 1.2 9.2 0.3 2.9 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.22 GAM41312.1 - 0.009 16.2 2.5 1.5 9.3 0.0 3.6 4 0 0 4 4 4 1 HEAT repeat Atx10homo_assoc PF09759.9 GAM41312.1 - 0.14 12.2 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain p450 PF00067.22 GAM41313.1 - 2.8e-63 214.3 0.0 3.9e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PA PF02225.22 GAM41316.1 - 7.3e-09 35.5 0.0 2e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 PA domain EI24 PF07264.11 GAM41317.1 - 4.7e-13 49.8 3.5 1.6e-12 48.1 3.5 1.9 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) LRR_8 PF13855.6 GAM41318.1 - 6.8e-08 32.2 5.8 6.8e-08 32.2 5.8 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 GAM41318.1 - 0.00012 22.4 12.4 0.00017 21.9 3.6 3.5 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM41318.1 - 4.1 8.3 8.8 14 6.7 0.2 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat Epimerase PF01370.21 GAM41319.1 - 1.3e-20 73.9 0.0 1.8e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM41319.1 - 2.2e-07 30.6 0.2 0.00029 20.4 0.0 2.5 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAM41319.1 - 2.5e-07 30.1 0.2 3.6e-07 29.6 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 GAM41319.1 - 1.4e-06 28.3 0.3 2e-06 27.8 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM41319.1 - 2e-06 27.6 0.1 9.1e-06 25.4 0.1 1.8 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 GAM41319.1 - 5.3e-06 25.6 0.0 1.2e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAM41319.1 - 0.00025 20.3 0.0 0.0012 18.1 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DFP PF04127.15 GAM41319.1 - 0.067 13.0 0.2 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein ADH_zinc_N PF00107.26 GAM41319.1 - 0.09 12.8 0.4 0.45 10.5 0.0 2.2 3 0 0 3 3 3 0 Zinc-binding dehydrogenase YAcAr PF10686.9 GAM41319.1 - 0.36 10.8 2.7 0.35 10.9 0.2 2.2 3 0 0 3 3 3 0 YspA, cpYpsA-related SLOG family MFS_1 PF07690.16 GAM41320.1 - 1.8e-22 79.8 52.2 2.8e-19 69.2 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.13 GAM41321.1 - 8.3e-32 110.6 0.0 1.1e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM41321.1 - 1.1e-09 38.4 0.1 6.9e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 GAM41321.1 - 0.00014 21.4 0.1 0.00026 20.5 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 GAM41321.1 - 0.19 11.9 0.1 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PEP_mutase PF13714.6 GAM41322.1 - 1.3e-65 221.2 2.5 1.5e-65 221.0 2.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Radical_SAM PF04055.21 GAM41322.1 - 0.058 13.8 0.2 0.19 12.1 0.1 1.9 1 1 0 1 1 1 0 Radical SAM superfamily DUF3658 PF12395.8 GAM41322.1 - 0.075 12.9 0.0 0.21 11.5 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function NmrA PF05368.13 GAM41322.1 - 0.12 11.9 0.6 1.5 8.3 0.6 2.5 1 1 0 1 1 1 0 NmrA-like family MFS_1 PF07690.16 GAM41323.1 - 5e-28 98.0 36.0 5e-28 98.0 36.0 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3576 PF12100.8 GAM41323.1 - 0.18 11.9 0.3 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3576) SnoaL PF07366.12 GAM41324.1 - 4.7e-27 94.3 0.0 5.5e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 GAM41324.1 - 9e-20 71.2 0.0 1.1e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 GAM41324.1 - 0.0072 16.7 0.0 0.01 16.2 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SANT_DAMP1_like PF16282.5 GAM41324.1 - 0.083 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 NRN1 PF15056.6 GAM41324.1 - 0.13 12.3 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Neuritin protein family SnoaL_3 PF13474.6 GAM41324.1 - 0.14 12.4 0.0 0.58 10.4 0.0 1.8 2 0 0 2 2 2 0 SnoaL-like domain Hydrolase_6 PF13344.6 GAM41325.1 - 3.8e-23 81.5 0.0 6.2e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM41325.1 - 4.5e-18 65.1 0.0 1.6e-17 63.3 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 GAM41325.1 - 0.00021 21.6 0.1 0.029 14.6 0.1 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAM41325.1 - 0.06 13.4 0.0 8.9 6.4 0.0 2.5 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAM41325.1 - 0.097 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase tRNA-synt_2 PF00152.20 GAM41326.1 - 2.7e-65 220.5 0.1 3.4e-65 220.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAM41326.1 - 1.7e-05 24.7 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1570 PF07607.11 GAM41326.1 - 0.15 12.4 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) SRP-alpha_N PF04086.13 GAM41326.1 - 0.48 10.3 3.8 1 9.2 3.8 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Med3 PF11593.8 GAM41326.1 - 4.7 6.3 7.1 6.6 5.8 7.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SIP1 PF04938.12 GAM41327.1 - 1.5e-11 44.4 0.0 4.7e-09 36.3 0.0 2.5 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Abhydrolase_6 PF12697.7 GAM41328.1 - 0.00088 19.9 0.3 0.0017 19.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAM41328.1 - 0.00098 18.9 1.6 0.0034 17.1 0.1 2.6 2 2 1 3 3 3 1 PGAP1-like protein UPF0227 PF05728.12 GAM41328.1 - 0.0066 16.4 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.25 GAM41328.1 - 0.022 14.6 0.1 0.055 13.3 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_3 PF07859.13 GAM41328.1 - 0.022 14.6 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 GAM41328.1 - 0.028 14.5 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain DUF676 PF05057.14 GAM41328.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 GAM41328.1 - 0.049 12.9 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PX PF00787.24 GAM41329.1 - 1.4e-16 60.5 0.2 3.8e-16 59.1 0.2 1.7 2 0 0 2 2 2 1 PX domain FAD_binding_3 PF01494.19 GAM41330.1 - 1.2e-90 304.3 0.0 1.8e-90 303.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAM41330.1 - 5e-58 195.8 0.0 9.2e-58 194.9 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 GAM41330.1 - 5.3e-05 22.6 0.1 0.00012 21.4 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM41330.1 - 0.00019 20.7 0.0 0.002 17.4 0.0 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 GAM41330.1 - 0.00043 19.1 0.0 0.00063 18.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 GAM41330.1 - 0.00048 19.3 0.0 0.0011 18.2 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 GAM41330.1 - 0.0017 17.4 0.0 0.0031 16.6 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 GAM41330.1 - 0.0031 16.6 0.1 0.0054 15.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAM41330.1 - 0.0058 16.8 0.0 0.021 15.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM41330.1 - 0.012 15.2 0.1 0.021 14.4 0.1 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM41330.1 - 0.016 15.7 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM41330.1 - 0.026 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAM41330.1 - 0.061 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAM41330.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_25 PF13649.6 GAM41331.1 - 1e-17 64.6 0.0 1.6e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM41331.1 - 1.8e-15 57.4 0.0 3.3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM41331.1 - 3.9e-15 56.1 0.0 4.9e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM41331.1 - 1.4e-10 41.8 0.0 2.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM41331.1 - 4.5e-10 39.5 0.0 6.6e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM41331.1 - 7.7e-06 25.4 0.0 9.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAM41331.1 - 3.5e-05 23.4 0.0 5.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 GAM41331.1 - 0.0029 17.1 0.0 0.19 11.2 0.0 2.3 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain CMAS PF02353.20 GAM41331.1 - 0.005 16.2 0.0 0.016 14.5 0.0 1.6 1 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 GAM41331.1 - 0.0054 16.4 0.0 0.0066 16.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 GAM41331.1 - 0.0094 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase UPF0146 PF03686.13 GAM41331.1 - 0.052 13.4 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) DASH_Dad1 PF08649.10 GAM41332.1 - 0.038 14.2 0.2 21 5.4 0.3 3.5 2 0 0 2 2 2 0 DASH complex subunit Dad1 PKcGMP_CC PF16808.5 GAM41332.1 - 0.061 13.2 7.8 9.3 6.2 0.2 4.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TcpS PF17456.2 GAM41332.1 - 1 9.4 9.9 0.29 11.2 2.8 3.8 2 1 2 4 4 4 0 Toxin-coregulated pilus protein S PKHD_C PF18331.1 GAM41332.1 - 1.4 9.0 14.6 16 5.6 0.2 5.2 5 0 0 5 5 5 0 PKHD-type hydroxylase C-terminal domain Sugar_tr PF00083.24 GAM41333.1 - 1.4e-88 297.8 28.0 1.7e-88 297.5 28.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM41333.1 - 3.6e-18 65.6 27.4 3.6e-18 65.6 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2663 PF10864.8 GAM41333.1 - 0.49 10.8 1.9 0.72 10.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) DUF2427 PF10348.9 GAM41333.1 - 1.2 8.9 7.0 0.28 11.0 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) DUF1700 PF08006.11 GAM41333.1 - 2.4 7.6 4.4 5.5 6.5 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF4149 PF13664.6 GAM41334.1 - 1.6e-24 86.2 1.0 1.6e-24 86.2 1.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) TPR_12 PF13424.6 GAM41335.1 - 1e-57 192.4 25.5 1.6e-18 66.8 0.1 5.6 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 GAM41335.1 - 1.2e-54 180.8 10.2 2.6e-10 39.8 0.1 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 GAM41335.1 - 8.5e-26 88.7 22.3 0.00015 21.4 1.3 7.2 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 GAM41335.1 - 1.9e-21 74.5 10.8 0.01 15.8 0.2 7.0 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAM41335.1 - 1.2e-19 68.8 17.2 0.00057 19.8 0.6 7.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM41335.1 - 3.2e-18 66.2 1.8 1.5e-09 37.7 0.1 3.5 1 1 2 3 3 3 3 MalT-like TPR region TPR_8 PF13181.6 GAM41335.1 - 3e-16 58.2 15.7 0.0023 18.0 0.8 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAM41335.1 - 3e-13 49.4 7.5 1.8 9.6 0.4 8.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM41335.1 - 6.4e-12 45.9 13.5 0.01 16.5 0.0 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 GAM41335.1 - 1.9e-11 43.7 0.0 4.9e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.22 GAM41335.1 - 7.8e-10 38.4 0.0 2.6e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain DUF2225 PF09986.9 GAM41335.1 - 1.2e-09 38.2 7.6 0.00027 20.7 0.5 4.7 2 1 3 5 5 5 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.6 GAM41335.1 - 4.1e-08 33.0 2.6 0.094 13.1 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat AAA_16 PF13191.6 GAM41335.1 - 1.2e-07 32.3 0.0 2.9e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TPR_6 PF13174.6 GAM41335.1 - 3.4e-06 27.3 20.8 0.16 12.6 1.1 6.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_21 PF09976.9 GAM41335.1 - 0.00066 19.4 11.2 1.4 8.6 0.0 5.7 3 2 2 5 5 5 1 Tetratricopeptide repeat-like domain SNAP PF14938.6 GAM41335.1 - 0.0033 16.9 0.1 0.0089 15.5 0.1 1.7 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP AAA_22 PF13401.6 GAM41335.1 - 0.015 15.5 0.0 0.066 13.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain TPR_19 PF14559.6 GAM41335.1 - 0.018 15.6 12.9 0.11 13.1 1.2 5.6 4 1 1 6 6 5 0 Tetratricopeptide repeat RPN6_N PF18055.1 GAM41335.1 - 0.03 14.7 1.7 7.7 6.9 0.0 3.9 4 0 0 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain NACHT PF05729.12 GAM41335.1 - 0.041 13.8 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 GAM41335.1 - 0.054 13.4 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea 14-3-3 PF00244.20 GAM41335.1 - 0.073 12.6 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 14-3-3 protein TniB PF05621.11 GAM41335.1 - 0.13 11.7 0.0 0.42 10.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein TPR_11 PF13414.6 GAM41335.1 - 0.17 11.6 24.2 1.4 8.7 0.2 6.2 6 2 2 8 8 7 0 TPR repeat DUF5344 PF17279.2 GAM41335.1 - 0.2 12.2 0.1 19 5.9 0.0 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5344) DUF1897 PF09005.10 GAM41335.1 - 0.4 10.2 3.5 15 5.2 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1897) Ku_PK_bind PF08785.11 GAM41336.1 - 1.2e-38 132.0 0.2 3e-38 130.7 0.2 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 GAM41336.1 - 4.7e-32 111.3 0.0 8.7e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 GAM41336.1 - 1e-12 48.3 0.0 2.1e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 GAM41336.1 - 0.00091 19.5 0.1 0.0025 18.1 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.14 GAM41336.1 - 0.0037 17.9 0.4 0.0037 17.9 0.4 2.4 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm Ribosomal_L7Ae PF01248.26 GAM41337.1 - 1.9e-15 56.4 0.0 2.8e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zinc_ribbon_16 PF17034.5 GAM41338.1 - 1.4e-17 64.0 17.9 4.3e-15 56.0 15.5 3.4 2 1 0 2 2 2 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 GAM41338.1 - 0.0026 17.3 7.2 0.0026 17.3 7.2 2.9 4 0 0 4 4 4 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 GAM41338.1 - 0.0051 17.1 1.6 0.023 15.0 1.6 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain HrpB1_HrpK PF09613.10 GAM41338.1 - 0.013 15.1 0.5 0.026 14.2 0.5 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) WD40 PF00400.32 GAM41338.1 - 0.036 14.9 0.3 1.8 9.6 0.6 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Efg1 PF10153.9 GAM41339.1 - 6.1e-31 107.1 16.2 6.1e-31 107.1 16.2 2.1 2 0 0 2 2 2 1 rRNA-processing protein Efg1 Pox_A_type_inc PF04508.12 GAM41339.1 - 0.57 10.1 3.8 0.26 11.2 0.7 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat F-box-like PF12937.7 GAM41340.1 - 2.5e-12 46.5 0.0 8.2e-12 44.8 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM41340.1 - 1.2e-09 37.8 0.0 4.9e-09 35.8 0.0 2.2 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 GAM41340.1 - 1.3e-08 34.2 7.5 0.077 13.1 0.1 6.6 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.7 GAM41340.1 - 2.2e-05 24.7 3.7 0.13 12.8 0.1 4.8 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) PRANC PF09372.10 GAM41340.1 - 0.00014 22.1 0.7 0.00073 19.8 0.0 2.2 2 0 0 2 2 2 1 PRANC domain LRR_1 PF00560.33 GAM41340.1 - 0.004 17.5 6.0 6.7 7.7 0.0 5.3 6 0 0 6 6 6 1 Leucine Rich Repeat Secretin_N_2 PF07655.13 GAM41340.1 - 0.12 13.0 1.7 0.43 11.1 0.0 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Pkinase PF00069.25 GAM41341.1 - 3.5e-56 190.5 0.0 5.4e-56 189.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM41341.1 - 3.5e-20 72.4 0.0 5.3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM41341.1 - 1.5e-05 24.5 0.0 3.6e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAM41341.1 - 0.00099 19.1 0.1 0.013 15.4 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM41341.1 - 0.0013 17.8 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 GAM41341.1 - 0.004 16.0 0.0 0.0076 15.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 GAM41341.1 - 0.0049 16.5 0.2 0.014 15.0 0.2 1.7 1 1 0 1 1 1 1 RIO1 family RabGAP-TBC PF00566.18 GAM41342.1 - 1.1e-16 61.2 0.8 1.1e-16 61.2 0.8 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Spc7 PF08317.11 GAM41342.1 - 1.1 8.1 8.3 1.7 7.5 8.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 GAM41342.1 - 1.2 8.5 6.4 1.9 7.7 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADH_N PF08240.12 GAM41344.1 - 1.8e-28 98.6 0.4 3.1e-28 97.8 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM41344.1 - 1.1e-16 61.0 0.0 2e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 GAM41344.1 - 1.1e-06 28.4 0.6 2.3e-06 27.4 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 GAM41344.1 - 1.8e-06 27.6 0.0 2.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAM41344.1 - 0.00095 20.2 0.0 0.002 19.2 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase KH_1 PF00013.29 GAM41345.1 - 5.8e-41 138.2 10.1 2.9e-17 62.2 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GAM41345.1 - 1.1e-09 38.0 10.2 0.0064 16.3 1.1 3.5 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 GAM41345.1 - 1.6e-07 31.1 6.8 0.03 14.2 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 GAM41345.1 - 0.00017 21.6 6.8 0.1 12.7 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain Peptidase_M41 PF01434.18 GAM41346.1 - 1.2e-69 234.0 0.0 1.7e-69 233.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAM41346.1 - 2.1e-43 147.9 0.0 5e-43 146.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM41346.1 - 7.5e-13 48.1 1.4 1.4e-12 47.2 0.2 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 GAM41346.1 - 0.00021 21.3 0.0 0.00095 19.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM41346.1 - 0.00046 20.6 1.0 0.066 13.6 0.2 3.2 3 1 1 4 4 4 1 AAA ATPase domain RuvB_N PF05496.12 GAM41346.1 - 0.0041 16.9 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAM41346.1 - 0.0042 17.4 0.1 0.57 10.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 GAM41346.1 - 0.0048 16.2 0.1 0.0096 15.2 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 GAM41346.1 - 0.018 15.1 0.0 0.067 13.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 GAM41346.1 - 0.045 14.2 0.0 0.097 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4890 PF16231.5 GAM41346.1 - 0.067 13.7 0.4 6.5 7.3 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4890) IstB_IS21 PF01695.17 GAM41346.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAM41346.1 - 0.12 11.7 0.3 0.3 10.4 0.3 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAM41346.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAM41346.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsH_ext PF06480.15 GAM41347.1 - 6.5e-10 39.3 0.6 9.7e-09 35.6 0.1 2.7 2 1 1 3 3 3 1 FtsH Extracellular DUF2508 PF10704.9 GAM41347.1 - 0.023 14.9 2.6 0.065 13.4 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) DUF2009 PF09418.10 GAM41347.1 - 0.14 11.2 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Fungal_trans PF04082.18 GAM41349.1 - 1.1e-23 83.6 0.0 2.6e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM41349.1 - 8.8e-10 38.6 13.1 1.5e-09 37.8 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pam16 PF03656.13 GAM41350.1 - 2.7e-07 30.6 0.0 3.9e-07 30.1 0.0 1.3 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 GAM41350.1 - 3.9e-05 23.7 0.1 6.5e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L24e PF01246.20 GAM41351.1 - 0.00015 21.9 0.9 0.00015 21.9 0.9 2.2 3 0 0 3 3 3 1 Ribosomal protein L24e Methyltransf_31 PF13847.6 GAM41353.1 - 1.9e-13 50.5 0.0 7.8e-07 29.0 0.0 3.1 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 GAM41353.1 - 1.5e-10 41.2 0.3 2.1e-06 27.7 0.3 2.9 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_16 PF10294.9 GAM41353.1 - 2.8e-10 40.2 0.0 6.9e-10 38.9 0.0 1.6 2 0 0 2 2 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 GAM41353.1 - 1.1e-07 32.5 0.0 0.00012 22.7 0.0 3.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM41353.1 - 2.1e-05 25.2 0.7 0.0025 18.5 0.0 3.9 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM41353.1 - 7.8e-05 23.3 0.0 0.0037 17.9 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 GAM41353.1 - 0.0092 15.4 0.0 2.7 7.3 0.0 2.7 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAM41353.1 - 0.01 15.4 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 GAM41353.1 - 0.011 15.8 0.0 0.078 13.1 0.0 2.3 2 1 0 2 2 2 0 FtsJ-like methyltransferase zf-C2H2 PF00096.26 GAM41353.1 - 0.02 15.4 3.4 0.047 14.2 3.4 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type BING4CT PF08149.11 GAM41353.1 - 0.16 11.8 0.0 0.89 9.4 0.0 2.3 1 0 0 1 1 1 0 BING4CT (NUC141) domain MetW PF07021.12 GAM41353.1 - 0.22 11.1 0.4 0.95 9.0 0.1 2.1 3 0 0 3 3 3 0 Methionine biosynthesis protein MetW zf-C2H2_4 PF13894.6 GAM41353.1 - 0.67 11.0 3.3 1.8 9.6 3.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger FAM176 PF14851.6 GAM41353.1 - 2.6 7.7 17.9 1.7 8.3 4.8 3.5 3 0 0 3 3 3 0 FAM176 family SDA1 PF05285.12 GAM41353.1 - 3.7 6.9 22.0 0.089 12.2 14.2 2.3 2 0 0 2 2 2 0 SDA1 Helo_like_N PF17111.5 GAM41354.1 - 1.6e-08 34.2 2.3 1.7e-07 30.8 1.1 2.7 3 1 0 3 3 3 1 Fungal N-terminal domain of STAND proteins IBR PF01485.21 GAM41354.1 - 0.17 12.2 1.3 0.44 10.8 1.3 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_3 PF13878.6 GAM41354.1 - 0.98 9.3 3.2 0.7 9.8 0.7 2.1 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO MIP PF00230.20 GAM41355.1 - 6e-39 134.1 6.5 8.7e-39 133.6 6.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein SPW PF03779.14 GAM41355.1 - 0.22 11.1 2.7 2 8.0 0.0 2.6 2 0 0 2 2 2 0 SPW repeat Abhydrolase_1 PF00561.20 GAM41356.1 - 1.7e-14 54.1 0.2 2.1e-14 53.8 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM41356.1 - 4.6e-08 33.9 5.3 6.8e-08 33.4 5.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM41356.1 - 2.1e-05 23.9 0.1 3.6e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Tannase PF07519.11 GAM41357.1 - 4.4e-105 352.3 0.9 5.1e-105 352.1 0.9 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 GAM41357.1 - 3.3e-06 26.7 0.1 0.00061 19.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 GAM41357.1 - 0.0012 18.2 0.0 0.0035 16.6 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Fungal_trans_2 PF11951.8 GAM41358.1 - 9.3e-05 21.4 1.8 0.0058 15.5 1.8 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 GAM41359.1 - 9.4e-19 67.5 62.7 3.7e-18 65.6 29.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM41359.1 - 0.0049 15.8 5.7 0.0049 15.8 5.7 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter DUF5134 PF17197.4 GAM41359.1 - 0.72 9.7 5.2 0.9 9.4 0.1 3.1 1 1 0 2 2 2 0 Domain of unknown function (DUF5134) Hira PF07569.11 GAM41360.1 - 5.4e-84 281.4 0.0 1.1e-83 280.4 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 GAM41360.1 - 7.6e-27 93.0 28.7 2.6e-05 24.9 0.0 9.0 7 1 1 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM41360.1 - 1.4e-13 50.9 0.0 0.4 11.0 0.2 5.9 4 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 GAM41360.1 - 2.7e-09 36.6 0.0 8.2e-09 35.1 0.0 1.9 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 GAM41360.1 - 9e-06 25.5 1.0 0.44 10.6 0.0 4.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 GAM41360.1 - 4.5e-05 22.6 0.2 2 7.3 0.0 4.7 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 GAM41360.1 - 0.16 10.0 0.0 0.34 8.9 0.0 1.5 1 0 0 1 1 1 0 IKI3 family Dicty_REP PF05086.12 GAM41360.1 - 1.5 6.7 3.4 2 6.3 3.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3484 PF11983.8 GAM41360.1 - 7.6 7.7 7.1 7.8 7.7 4.2 2.4 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch Band_7 PF01145.25 GAM41361.1 - 2e-30 106.1 0.5 4.3e-30 105.0 0.5 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 GAM41361.1 - 2.9e-25 88.1 0.9 1.1e-24 86.2 0.9 2.1 1 0 0 1 1 1 1 C-terminal region of band_7 DRTGG PF07085.12 GAM41361.1 - 0.027 14.3 0.5 0.66 9.8 0.0 2.4 1 1 0 2 2 2 0 DRTGG domain Pox_A11 PF05061.13 GAM41361.1 - 0.09 12.0 0.2 0.15 11.3 0.2 1.4 1 0 0 1 1 1 0 Poxvirus A11 Protein La PF05383.17 GAM41362.1 - 1.4e-18 66.7 0.1 2.3e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 La domain NPR3 PF03666.13 GAM41363.1 - 7.5e-154 513.0 0.0 7.5e-154 513.0 0.0 1.5 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Ribosomal_S30AE PF02482.19 GAM41363.1 - 0.16 12.8 2.9 8 7.3 0.9 2.5 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein CHCH PF06747.13 GAM41364.1 - 8e-07 29.0 1.0 1.3e-06 28.4 1.0 1.4 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 GAM41364.1 - 0.00076 19.8 2.6 0.0078 16.5 0.3 2.3 1 1 1 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 GAM41364.1 - 0.0056 17.0 2.8 0.032 14.5 0.9 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 GAM41364.1 - 0.022 14.5 0.2 0.031 14.0 0.2 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Aldo_ket_red PF00248.21 GAM41365.1 - 9.7e-51 172.7 0.0 3.1e-50 171.0 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Mod_r PF07200.13 GAM41366.1 - 1.1e-24 87.1 3.8 1.5e-24 86.8 3.8 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein PspA_IM30 PF04012.12 GAM41366.1 - 0.17 11.4 4.4 0.25 10.9 4.4 1.3 1 0 0 1 1 1 0 PspA/IM30 family Sugar_tr PF00083.24 GAM41367.1 - 2e-106 356.6 19.2 2.3e-106 356.4 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM41367.1 - 1.5e-30 106.4 56.2 5.6e-25 88.0 30.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4083 PF13314.6 GAM41367.1 - 0.26 11.3 2.6 6.9 6.7 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) TRI12 PF06609.13 GAM41367.1 - 0.92 7.8 9.9 0.028 12.8 1.1 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) 7TM-7TMR_HD PF07698.11 GAM41367.1 - 4.6 7.0 20.8 0.61 9.8 6.5 3.5 2 2 0 2 2 2 0 7TM receptor with intracellular HD hydrolase OATP PF03137.20 GAM41367.1 - 4.6 5.4 11.3 0.54 8.5 2.3 2.7 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Dynamin_N PF00350.23 GAM41368.1 - 1.3e-21 77.4 0.2 1.3e-21 77.4 0.2 2.6 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 GAM41368.1 - 4.8e-19 68.7 4.0 1.5e-18 67.1 1.2 2.8 1 1 1 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 GAM41368.1 - 2.5e-08 34.0 0.5 1.2e-07 31.8 0.5 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM41368.1 - 0.00018 21.0 0.0 0.44 10.1 0.0 2.9 2 1 0 2 2 2 2 Ferrous iron transport protein B GED PF02212.18 GAM41368.1 - 0.012 15.7 0.1 0.13 12.4 0.0 2.6 2 0 0 2 2 2 0 Dynamin GTPase effector domain AAA_15 PF13175.6 GAM41368.1 - 0.085 12.5 7.2 0.15 11.7 3.9 3.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 GAM41368.1 - 0.43 10.9 2.1 1.3 9.4 0.1 2.9 3 1 0 3 3 3 0 AAA ATPase domain YchF-GTPase_C PF06071.13 GAM41369.1 - 6.2e-36 122.5 0.1 1.6e-35 121.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 GAM41369.1 - 2.2e-16 59.9 0.0 8e-16 58.1 0.0 1.9 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM41369.1 - 0.00095 18.7 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 GAM41369.1 - 0.0029 17.6 0.0 0.008 16.2 0.0 1.8 1 0 0 1 1 1 1 TGS domain AAA_23 PF13476.6 GAM41369.1 - 7.3 7.0 6.6 1.4e+02 2.9 6.7 2.4 1 1 0 1 1 1 0 AAA domain Pre-PUA PF17832.1 GAM41370.1 - 7e-24 84.3 0.1 9.5e-24 83.9 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 GAM41370.1 - 1e-13 51.1 0.1 1.4e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 PUA domain RIC1 PF07064.13 GAM41371.1 - 9e-87 290.6 0.1 1.4e-86 290.1 0.1 1.3 1 0 0 1 1 1 1 RIC1 WD40 PF00400.32 GAM41371.1 - 0.079 13.9 1.1 13 6.9 0.0 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat cwf18 PF08315.12 GAM41371.1 - 0.16 12.6 0.1 0.32 11.6 0.1 1.4 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor SGTA_dimer PF16546.5 GAM41372.1 - 5.7e-25 86.9 0.1 9.2e-25 86.2 0.1 1.3 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 GAM41372.1 - 1.2e-14 53.4 7.6 1.7e-05 24.5 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM41372.1 - 2.4e-13 49.1 10.1 0.00013 21.8 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM41372.1 - 1.7e-10 40.4 10.6 2.9e-06 26.8 1.8 3.3 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 GAM41372.1 - 1.8e-08 33.9 6.6 0.021 15.0 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAM41372.1 - 1.9e-07 31.0 1.8 0.0034 17.7 0.6 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM41372.1 - 5.8e-07 30.1 20.3 0.0001 22.9 4.8 3.1 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM41372.1 - 1e-06 29.0 8.4 0.11 13.3 1.3 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAM41372.1 - 2.1e-06 27.4 1.0 0.18 11.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM41372.1 - 5.4e-06 26.5 2.5 4.7e-05 23.5 1.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM41372.1 - 2.9e-05 24.5 4.7 0.0029 18.1 0.9 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM41372.1 - 3.9e-05 23.8 8.2 0.0027 18.0 2.0 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat STI1 PF17830.1 GAM41372.1 - 0.00013 21.8 6.2 0.003 17.4 2.9 2.5 2 0 0 2 2 2 1 STI1 domain XPC-binding PF09280.11 GAM41372.1 - 0.014 15.1 1.5 0.031 14.0 1.5 1.6 1 0 0 1 1 1 0 XPC-binding domain TPR_6 PF13174.6 GAM41372.1 - 0.019 15.5 4.5 0.66 10.7 0.4 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 GAM41372.1 - 0.043 14.3 2.9 0.087 13.3 1.9 1.9 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 GAM41372.1 - 0.047 13.6 11.3 0.16 11.8 0.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 GAM41372.1 - 0.13 12.3 1.8 3.3 7.8 0.1 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Tim44 PF04280.15 GAM41373.1 - 7.6e-35 120.2 0.0 2e-34 118.8 0.0 1.8 2 0 0 2 2 2 1 Tim44-like domain Med7 PF05983.11 GAM41373.1 - 0.077 13.1 4.8 0.18 11.9 4.8 1.6 1 0 0 1 1 1 0 MED7 protein DUF2052 PF09747.9 GAM41373.1 - 7.3 6.7 15.6 0.29 11.2 7.5 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FYDLN_acid PF09538.10 GAM41373.1 - 8.5 7.1 9.9 0.86 10.3 4.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Ribosomal_S11 PF00411.19 GAM41374.1 - 4.2e-09 36.8 0.0 7.8e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 VPS9 PF02204.18 GAM41375.1 - 3.1e-17 62.7 0.0 7.1e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 GAM41375.1 - 6.7e-16 58.2 0.1 2.8e-14 53.0 0.0 3.6 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM41375.1 - 8.3e-11 42.3 0.3 0.01 16.4 0.0 4.4 3 1 2 6 6 6 4 Ankyrin repeats (3 copies) PX PF00787.24 GAM41375.1 - 7.6e-08 32.3 0.1 3.8e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 PX domain Ank PF00023.30 GAM41375.1 - 0.00018 21.8 1.1 2.9 8.5 0.1 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 GAM41375.1 - 0.00019 21.9 0.1 3 8.6 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM41375.1 - 0.0023 18.3 0.2 4.1 8.3 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat SRP54 PF00448.22 GAM41375.1 - 0.0069 16.0 0.0 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ThiJ_like PF17124.5 GAM41375.1 - 0.15 11.7 0.0 13 5.4 0.0 2.6 2 0 0 2 2 2 0 ThiJ/PfpI family-like BsuBI_PstI_RE_N PF17728.1 GAM41375.1 - 0.4 10.6 2.7 0.37 10.7 0.7 1.9 2 0 0 2 2 2 0 BsuBI/PstI restriction endonuclease HTH domain FAM176 PF14851.6 GAM41376.1 - 0.0079 15.9 0.6 0.018 14.7 0.4 1.8 1 1 0 1 1 1 1 FAM176 family FecCD PF01032.18 GAM41376.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 FecCD transport family Tmemb_9 PF05434.11 GAM41376.1 - 0.16 11.9 0.2 0.41 10.5 0.2 1.7 1 1 0 1 1 1 0 TMEM9 Mucin15 PF15672.5 GAM41376.1 - 0.24 10.9 0.1 0.24 10.9 0.1 2.3 1 1 1 2 2 2 0 Cell-membrane associated Mucin15 DUF4644 PF15486.6 GAM41377.1 - 0.29 10.9 2.1 0.44 10.3 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4644) Inhibitor_I78 PF11720.8 GAM41378.1 - 4.9e-10 39.3 0.0 6.1e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 GAM41378.1 - 0.016 15.9 0.1 0.022 15.5 0.1 1.2 1 0 0 1 1 1 0 Potato inhibitor I family HMG_box PF00505.19 GAM41379.1 - 5.5e-10 39.5 12.3 1.9e-09 37.8 0.1 3.5 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAM41379.1 - 6.5e-07 29.8 0.2 6.5e-07 29.8 0.2 3.5 3 1 0 3 3 3 1 HMG-box domain FAM199X PF15814.5 GAM41379.1 - 0.078 12.0 2.5 0.13 11.3 2.5 1.3 1 0 0 1 1 1 0 Protein family FAM199X Mito_carr PF00153.27 GAM41381.1 - 1.7e-45 152.8 2.7 1e-17 63.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein JAB PF01398.21 GAM41382.1 - 1.2e-08 34.9 0.2 3.3e-07 30.3 0.2 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Abhydrolase_3 PF07859.13 GAM41383.1 - 7.4e-05 22.7 1.4 0.00033 20.6 1.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM41383.1 - 0.0058 17.2 1.2 0.0087 16.7 1.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM41383.1 - 0.024 14.3 0.1 0.049 13.3 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF3089 PF11288.8 GAM41383.1 - 0.056 13.0 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) CK_II_beta PF01214.18 GAM41384.1 - 8.4e-77 257.1 0.2 1.1e-76 256.7 0.2 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 GAM41384.1 - 0.17 12.0 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Aldo_ket_red PF00248.21 GAM41385.1 - 7.3e-31 107.4 0.0 9.9e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Nefa_Nip30_N PF10187.9 GAM41386.1 - 3.6e-34 117.3 12.5 9.7e-34 115.9 12.5 1.8 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Seryl_tRNA_N PF02403.22 GAM41386.1 - 0.19 12.0 9.1 0.065 13.5 4.6 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sugar_tr PF00083.24 GAM41387.1 - 6.1e-101 338.5 22.6 7e-101 338.3 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM41387.1 - 7.6e-27 94.1 36.1 7.7e-20 71.1 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MatC_N PF07158.11 GAM41387.1 - 0.0027 17.8 1.1 0.009 16.1 1.1 1.9 1 0 0 1 1 1 1 Dicarboxylate carrier protein MatC N-terminus Gly-zipper_Omp PF13488.6 GAM41387.1 - 0.31 11.1 4.2 0.85 9.7 4.2 1.7 1 0 0 1 1 1 0 Glycine zipper Alpha-L-AF_C PF06964.12 GAM41388.1 - 4.7e-28 98.4 0.0 7.1e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain DEAD PF00270.29 GAM41389.1 - 3.7e-49 166.9 0.0 1.1e-48 165.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM41389.1 - 4.6e-27 94.6 0.0 1.6e-26 92.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM41389.1 - 0.0074 16.3 0.0 0.024 14.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Fungal_trans PF04082.18 GAM41390.1 - 1.3e-14 53.9 0.2 1.8e-14 53.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAXX PF15384.6 GAM41390.1 - 0.21 11.3 0.4 1.5 8.4 0.1 2.1 2 0 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Sugar_tr PF00083.24 GAM41391.1 - 4.2e-85 286.3 17.3 4.9e-85 286.1 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM41391.1 - 1.5e-30 106.4 46.0 9.3e-26 90.6 27.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM41391.1 - 0.00014 20.4 1.4 0.00014 20.4 1.4 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AnmK PF03702.14 GAM41392.1 - 2e-86 290.4 0.0 2.3e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase WLM PF08325.10 GAM41393.1 - 0.00057 20.0 0.7 0.00057 20.0 0.7 1.7 2 0 0 2 2 2 1 WLM domain SVIP PF15811.5 GAM41393.1 - 2.6 8.5 13.2 2.6 8.6 11.5 1.9 1 1 0 1 1 1 0 Small VCP/p97-interacting protein adh_short_C2 PF13561.6 GAM41394.1 - 1.1e-42 146.2 0.0 7.8e-37 127.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM41394.1 - 1.8e-40 138.5 0.0 2.4e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM41394.1 - 6.4e-14 52.3 0.0 1.1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM41394.1 - 1e-05 25.1 0.1 0.0002 20.9 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM41394.1 - 0.004 16.6 0.0 0.064 12.7 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase ADH_N PF08240.12 GAM41395.1 - 1.9e-17 63.1 0.4 5.2e-17 61.7 0.4 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM41395.1 - 5.2e-12 45.9 0.0 8.3e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM41395.1 - 0.0013 19.8 0.0 0.0024 18.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TOBE_2 PF08402.10 GAM41395.1 - 0.08 13.1 0.0 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 TOBE domain PEP_hydrolase PF09370.10 GAM41397.1 - 2.7e-136 453.1 0.4 3e-136 452.9 0.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 GAM41397.1 - 0.0064 15.9 0.8 0.0073 15.7 0.1 1.4 2 0 0 2 2 2 1 Nitronate monooxygenase Radical_SAM PF04055.21 GAM41397.1 - 0.17 12.2 0.0 1.4 9.2 0.0 2.1 1 1 1 2 2 2 0 Radical SAM superfamily UPF0261 PF06792.11 GAM41398.1 - 4.3e-165 549.6 0.9 4.8e-165 549.4 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) zf-H2C2_2 PF13465.6 GAM41399.1 - 6.8e-06 26.3 2.8 6.8e-06 26.3 2.8 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 GAM41399.1 - 6.1e-05 23.2 4.0 6.1e-05 23.2 4.0 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 GAM41399.1 - 0.00027 20.8 0.8 0.00027 20.8 0.8 2.9 5 0 0 5 5 5 1 C2H2-type zinc finger zf-met PF12874.7 GAM41399.1 - 0.00061 20.1 8.9 0.0023 18.3 0.6 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAM41399.1 - 0.001 19.7 2.1 0.001 19.7 2.1 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger DUF2225 PF09986.9 GAM41399.1 - 0.0079 15.9 0.3 0.018 14.8 0.3 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-Di19 PF05605.12 GAM41399.1 - 0.01 16.1 4.8 0.01 16.1 4.8 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SRR1 PF07985.12 GAM41400.1 - 7.3e-06 25.9 0.0 1.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 SRR1 adh_short PF00106.25 GAM41401.1 - 3.7e-28 98.3 0.0 2.5e-20 72.8 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM41401.1 - 7.8e-17 61.6 0.0 1.7e-11 44.2 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM41401.1 - 5.7e-06 26.3 0.0 8.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Rax2 PF12768.7 GAM41402.1 - 0.00017 21.1 4.2 0.00032 20.2 0.3 2.5 1 1 1 2 2 2 1 Cortical protein marker for cell polarity Kelch_4 PF13418.6 GAM41402.1 - 0.0017 18.3 0.9 3.3 7.8 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM41402.1 - 0.0041 17.4 2.3 0.11 12.8 0.2 3.5 4 0 0 4 4 4 1 Kelch motif Mid2 PF04478.12 GAM41402.1 - 0.11 12.3 2.3 0.22 11.3 2.3 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4690 PF15756.5 GAM41402.1 - 0.82 10.3 8.6 1.5 9.5 5.8 2.7 1 1 0 2 2 2 0 Small Novel Rich in Cartilage HAT PF02184.16 GAM41403.1 - 2.3e-25 88.2 78.5 5.3e-15 55.1 4.1 14.3 15 0 0 15 15 15 7 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 GAM41403.1 - 9.5e-21 72.7 23.1 0.0029 18.3 0.2 11.2 8 4 4 12 12 11 7 Tetratricopeptide repeat TPR_19 PF14559.6 GAM41403.1 - 2.9e-18 66.1 0.0 2.4e-05 24.8 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat Suf PF05843.14 GAM41403.1 - 9.1e-16 58.7 27.7 3.4e-05 24.0 1.2 7.2 2 1 6 8 8 8 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 GAM41403.1 - 8.2e-10 38.4 2.3 0.06 13.8 0.0 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM41403.1 - 2.8e-08 33.4 7.9 5.2 7.5 0.0 8.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM41403.1 - 0.00062 20.2 19.3 21 6.0 0.0 8.7 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAM41403.1 - 0.0011 19.6 6.3 13 6.5 0.1 7.2 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM41403.1 - 0.0029 17.9 15.3 6.6 7.1 0.0 7.7 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM41403.1 - 0.009 16.1 18.2 1.1 9.5 0.0 8.1 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM41403.1 - 0.065 13.1 5.3 50 4.0 0.3 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 GAM41403.1 - 0.34 11.0 27.8 0.08 13.0 2.8 7.1 5 2 3 8 8 8 0 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 GAM41403.1 - 1.2 8.2 30.1 2.3 7.2 5.2 6.1 2 2 3 5 5 5 0 NRDE-2, necessary for RNA interference Nop PF01798.18 GAM41404.1 - 3.4e-63 213.2 0.0 4.8e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 GAM41404.1 - 2.2e-47 160.9 1.2 5.6e-47 159.6 1.2 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain AdoHcyase PF05221.17 GAM41406.1 - 8.1e-129 429.0 0.0 2.5e-74 250.1 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 GAM41406.1 - 1.8e-83 278.5 1.8 2.9e-83 277.8 1.8 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAM41406.1 - 8.8e-08 31.7 0.1 1.8e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 GAM41406.1 - 0.00086 18.9 0.2 0.0017 18.0 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 GAM41406.1 - 0.0061 16.3 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 GAM41406.1 - 0.012 15.8 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 GAM41406.1 - 0.014 15.3 0.5 0.025 14.5 0.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GAM41406.1 - 0.12 13.0 0.3 0.23 12.0 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 GAM41406.1 - 0.12 12.8 0.3 0.37 11.3 0.2 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding TFIIF_alpha PF05793.12 GAM41407.1 - 7.1 5.1 34.9 13 4.2 34.9 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Aldo_ket_red PF00248.21 GAM41408.1 - 3.8e-63 213.4 0.0 4.6e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PMC2NT PF08066.12 GAM41408.1 - 0.086 13.5 0.0 0.23 12.2 0.0 1.6 2 0 0 2 2 2 0 PMC2NT (NUC016) domain FMO-like PF00743.19 GAM41409.1 - 4.7e-69 233.2 0.0 7.4e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAM41409.1 - 6.4e-14 51.9 0.0 3.3e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM41409.1 - 2.2e-12 46.8 1.5 1.4e-08 34.3 0.1 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 GAM41409.1 - 3.5e-08 33.1 0.0 9.7e-07 28.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM41409.1 - 8.9e-08 32.3 0.0 2.2e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAM41409.1 - 5.3e-06 26.5 0.1 0.0014 18.6 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 GAM41409.1 - 0.00013 21.3 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 GAM41409.1 - 0.00015 22.2 0.0 0.2 12.1 0.0 2.5 2 1 0 2 2 2 2 Putative NAD(P)-binding Pyr_redox PF00070.27 GAM41409.1 - 0.00021 21.8 0.2 0.046 14.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 GAM41409.1 - 0.00035 20.2 0.0 0.021 14.4 0.0 2.9 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 GAM41409.1 - 0.0004 20.5 0.1 2.1 8.4 0.0 3.0 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 GAM41409.1 - 0.00044 19.6 0.0 0.0013 18.1 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Glu_dehyd_C PF16912.5 GAM41409.1 - 0.0012 18.4 0.3 0.0052 16.3 0.0 2.1 3 0 0 3 3 3 1 Glucose dehydrogenase C-terminus DAO PF01266.24 GAM41409.1 - 0.0012 18.5 0.0 0.073 12.6 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAM41409.1 - 0.022 14.0 0.1 0.07 12.4 0.0 1.9 3 0 0 3 3 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 GAM41409.1 - 0.023 14.8 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Amino_oxidase PF01593.24 GAM41409.1 - 0.036 13.3 0.1 0.89 8.8 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 GAM41409.1 - 0.047 12.8 0.0 0.094 11.8 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 GAM41409.1 - 0.066 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.23 GAM41409.1 - 0.076 13.0 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.14 GAM41409.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF4147 PF13660.6 GAM41409.1 - 0.21 11.1 0.0 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) zf-H2C2_2 PF13465.6 GAM41410.1 - 1e-07 32.1 6.8 2.4e-06 27.7 0.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 GAM41410.1 - 6.1e-07 29.3 1.5 0.01 15.8 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM41410.1 - 7.2e-06 26.2 0.3 7.2e-06 26.2 0.3 3.7 3 1 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 GAM41410.1 - 1.1e-05 26.0 4.2 0.15 12.7 0.8 3.0 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 GAM41410.1 - 0.00043 20.9 7.0 0.0049 17.6 0.2 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 GAM41410.1 - 0.21 11.4 0.8 0.54 10.1 0.0 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 GAM41410.1 - 0.41 11.0 2.2 2.6 8.5 0.2 2.8 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zap1_zf2 PF18217.1 GAM41410.1 - 2.9 8.0 12.5 7 6.7 5.3 3.0 2 1 0 2 2 2 0 Zap1 zinc finger 2 zf-H2C2_5 PF13909.6 GAM41410.1 - 8.7 6.2 8.0 0.6 9.9 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain SNF2_N PF00176.23 GAM41411.1 - 4.3e-56 190.1 0.0 6.7e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 GAM41411.1 - 5.3e-22 77.5 4.4 6.4e-14 51.6 1.1 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 GAM41411.1 - 2.4e-20 72.9 0.0 5.8e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 GAM41411.1 - 1.6e-09 38.1 0.0 1.6e-09 38.1 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.8 GAM41411.1 - 2.9e-08 33.2 0.0 7.3e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 GAM41411.1 - 7e-08 32.7 0.0 2.7e-05 24.2 0.0 3.0 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 GAM41411.1 - 9.9e-07 29.1 5.2 4.2e-06 27.1 1.4 4.1 3 1 1 4 4 4 2 Chromodomain helicase DNA-binding domain 1 CHDCT2 PF08074.11 GAM41411.1 - 0.0077 16.4 0.1 0.032 14.4 0.0 2.2 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain ABC_tran PF00005.27 GAM41412.1 - 4.5e-37 127.6 0.0 4.4e-17 62.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 GAM41412.1 - 3e-14 52.6 5.5 3e-14 52.6 5.5 2.1 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 GAM41412.1 - 4.4e-14 53.0 6.8 0.0069 16.2 0.0 4.2 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM41412.1 - 1.7e-12 47.3 2.4 0.00072 19.0 0.1 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAM41412.1 - 2.9e-06 27.8 0.0 0.015 15.7 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 GAM41412.1 - 3.3e-06 27.6 0.0 0.014 15.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GAM41412.1 - 1e-05 26.1 0.0 0.41 11.2 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 GAM41412.1 - 1.2e-05 25.6 0.1 0.01 16.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 GAM41412.1 - 1.3e-05 25.1 0.6 0.37 10.5 0.0 3.1 2 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 GAM41412.1 - 4.1e-05 23.2 0.6 0.12 12.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4 PF00037.27 GAM41412.1 - 7.3e-05 22.4 2.5 7.3e-05 22.4 2.5 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain Rad17 PF03215.15 GAM41412.1 - 0.00017 21.6 0.0 0.076 12.9 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 GAM41412.1 - 0.00037 20.5 0.1 0.38 10.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_13 PF13166.6 GAM41412.1 - 0.00058 18.7 0.8 0.0035 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAM41412.1 - 0.00059 19.6 0.2 0.1 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAM41412.1 - 0.00072 19.3 0.6 1.5 8.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 GAM41412.1 - 0.00076 19.8 1.0 0.78 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAM41412.1 - 0.001 19.2 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GAM41412.1 - 0.0013 19.1 0.4 1.1 9.7 0.0 2.9 3 0 0 3 3 2 1 RNA helicase Fer4_21 PF14697.6 GAM41412.1 - 0.0022 18.1 11.3 0.0045 17.1 11.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 GAM41412.1 - 0.0034 17.4 12.3 0.0077 16.3 2.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain TsaE PF02367.17 GAM41412.1 - 0.0042 17.1 0.2 0.063 13.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 GAM41412.1 - 0.0042 16.6 0.1 0.51 9.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 GAM41412.1 - 0.0045 17.0 1.3 0.73 9.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 GAM41412.1 - 0.0057 17.2 4.7 0.41 11.1 0.4 2.6 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 GAM41412.1 - 0.0081 15.4 0.0 2.1 7.5 0.0 2.8 2 1 1 3 3 3 1 NB-ARC domain AAA_14 PF13173.6 GAM41412.1 - 0.015 15.3 0.6 2.7 8.1 0.1 3.3 3 1 0 3 3 2 0 AAA domain AAA_25 PF13481.6 GAM41412.1 - 0.019 14.6 0.5 2.3 7.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain Fer4_10 PF13237.6 GAM41412.1 - 0.021 14.9 15.6 0.022 14.9 1.6 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain NACHT PF05729.12 GAM41412.1 - 0.025 14.5 2.3 1 9.3 0.1 2.8 3 0 0 3 3 3 0 NACHT domain VirE PF05272.11 GAM41412.1 - 0.029 14.1 0.0 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E MMR_HSR1 PF01926.23 GAM41412.1 - 0.032 14.3 0.2 12 6.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.22 GAM41412.1 - 0.033 13.8 3.3 0.67 9.6 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.17 GAM41412.1 - 0.038 13.7 1.0 6.5 6.4 0.0 2.8 3 0 0 3 3 2 0 Thymidylate kinase DUF815 PF05673.13 GAM41412.1 - 0.053 12.7 0.0 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fer4_9 PF13187.6 GAM41412.1 - 0.072 13.3 11.7 0.15 12.3 11.7 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 GAM41412.1 - 0.078 13.9 0.3 0.078 13.9 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain KAP_NTPase PF07693.14 GAM41412.1 - 0.091 12.0 0.0 6.7 5.9 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain PduV-EutP PF10662.9 GAM41412.1 - 0.091 12.5 2.1 0.21 11.3 0.1 2.5 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation ATPase PF06745.13 GAM41412.1 - 0.093 12.1 1.5 0.16 11.3 0.1 1.9 2 0 0 2 2 2 0 KaiC DLIC PF05783.11 GAM41412.1 - 0.094 11.5 0.4 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) MukB PF04310.12 GAM41412.1 - 0.28 11.0 0.6 13 5.5 0.0 2.6 3 0 0 3 3 2 0 MukB N-terminal Fer4_8 PF13183.6 GAM41412.1 - 0.29 11.6 6.7 0.29 11.6 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 GAM41412.1 - 0.6 10.7 12.7 0.069 13.7 1.6 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain CLP1_P PF16575.5 GAM41412.1 - 0.63 9.8 1.9 6.5 6.5 0.1 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Fer4_2 PF12797.7 GAM41412.1 - 1.8 8.8 9.9 0.25 11.5 1.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain NTPase_1 PF03266.15 GAM41412.1 - 2.1 8.2 3.6 11 5.9 0.2 2.8 3 0 0 3 3 3 0 NTPase Fer4_17 PF13534.6 GAM41412.1 - 6.1 7.5 10.4 0.21 12.2 0.8 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain FF PF01846.19 GAM41413.1 - 1.5e-50 169.1 19.7 3.6e-13 49.5 0.0 7.0 6 1 0 6 6 6 5 FF domain WW PF00397.26 GAM41413.1 - 6.3e-17 61.4 13.0 6.8e-08 32.5 0.4 2.7 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 GAM41413.1 - 0.53 10.6 7.5 8.3 6.7 2.6 2.7 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Trs65 PF12735.7 GAM41414.1 - 1.7e-93 313.5 0.0 1.1e-91 307.6 0.0 2.1 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.12 GAM41415.1 - 5.9e-20 71.3 2.5 8.7e-20 70.7 0.1 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.19 GAM41416.1 - 1.5e-148 494.8 0.6 1.7e-148 494.6 0.6 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 GAM41416.1 - 0.054 13.5 0.7 0.37 10.8 0.0 2.6 3 0 0 3 3 3 0 PA domain DUF3530 PF12048.8 GAM41416.1 - 0.06 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DSS1_SEM1 PF05160.13 GAM41417.1 - 2.7e-23 81.8 17.1 3.5e-23 81.4 17.1 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DUF3808 PF10300.9 GAM41418.1 - 2.4e-143 478.3 0.0 3e-143 478.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) PspA_IM30 PF04012.12 GAM41418.1 - 0.08 12.5 6.5 0.12 11.9 0.3 3.1 3 0 0 3 3 3 0 PspA/IM30 family MFS_1 PF07690.16 GAM41419.1 - 2.1e-28 99.3 65.2 2.2e-27 95.9 42.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Nup160 PF11715.8 GAM41420.1 - 1e-151 506.2 2.8 1.3e-151 505.9 2.8 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Rad51 PF08423.11 GAM41421.1 - 2.6e-129 429.9 0.0 3.2e-129 429.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 GAM41421.1 - 1.9e-10 40.6 0.0 2.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 GAM41421.1 - 2.1e-09 37.2 0.0 2.9e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 GAM41421.1 - 3.6e-06 27.5 0.9 1e-05 26.0 0.4 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 GAM41421.1 - 2.6e-05 23.7 0.6 0.00011 21.6 0.6 2.0 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 GAM41421.1 - 0.0017 17.7 0.2 0.02 14.3 0.0 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 GAM41421.1 - 0.023 15.0 0.3 0.099 12.9 0.3 2.0 1 1 0 1 1 1 0 AAA domain PAXNEB PF05625.11 GAM41421.1 - 0.038 13.1 0.4 0.33 10.1 0.1 2.0 2 0 0 2 2 2 0 PAXNEB protein Ldr_toxin PF13940.6 GAM41422.1 - 4.9 7.3 5.3 1.1 9.4 0.2 2.1 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system CPL PF08144.11 GAM41423.1 - 3.5e-30 105.2 0.0 5.8e-29 101.3 0.0 3.0 3 0 0 3 3 3 1 CPL (NUC119) domain Nop14 PF04147.12 GAM41423.1 - 0.25 9.5 30.4 0.37 8.9 30.4 1.2 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 GAM41423.1 - 0.41 10.6 32.8 1.3 9.0 32.8 1.8 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) LAP1C PF05609.12 GAM41423.1 - 1 8.4 16.1 1.9 7.5 16.1 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 GAM41423.1 - 2 7.1 14.4 3 6.5 14.4 1.3 1 0 0 1 1 1 0 Presenilin SURF2 PF05477.11 GAM41423.1 - 5.5 6.6 22.0 14 5.3 22.0 1.7 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) TT_ORF2 PF02957.15 GAM41424.1 - 5.3 8.0 6.8 5.6 7.9 2.3 3.0 2 0 0 2 2 2 0 TT viral ORF2 Zn_clus PF00172.18 GAM41425.1 - 0.0074 16.4 7.2 0.019 15.1 7.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-BED PF02892.15 GAM41425.1 - 0.011 15.8 0.2 0.026 14.5 0.2 1.7 1 0 0 1 1 1 0 BED zinc finger HbrB PF08539.11 GAM41425.1 - 0.099 12.6 0.7 0.25 11.3 0.2 1.9 2 0 0 2 2 2 0 HbrB-like DIOX_N PF14226.6 GAM41426.1 - 2.6e-13 50.7 0.0 4.7e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM41426.1 - 2.2e-12 47.3 0.0 4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_3 PF07859.13 GAM41427.1 - 6.6e-29 101.3 0.0 2.5e-28 99.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAM41427.1 - 0.18 10.6 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Lipocalin_5 PF13924.6 GAM41428.1 - 6.9e-34 116.7 0.0 9.9e-34 116.2 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain GMC_oxred_C PF05199.13 GAM41428.1 - 2.6e-12 47.5 0.0 3.9e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DNA_pol_B_palm PF14792.6 GAM41429.1 - 1.3e-33 115.6 0.0 4.5e-33 113.9 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 GAM41429.1 - 2.3e-24 85.3 0.0 1e-23 83.3 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.6 GAM41429.1 - 1.2e-19 70.4 1.0 2.6e-19 69.3 1.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 GAM41429.1 - 4.9e-19 67.9 0.2 4.5e-18 64.8 0.2 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda BRCT PF00533.26 GAM41429.1 - 5.1e-06 26.8 0.0 1.3e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAM41429.1 - 0.017 15.6 0.1 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain TAT_signal PF10518.9 GAM41429.1 - 0.022 14.6 0.2 0.047 13.6 0.2 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence NTP_transf_2 PF01909.23 GAM41429.1 - 0.039 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF1539 PF07560.11 GAM41429.1 - 0.12 12.4 0.9 2.8 8.0 0.5 3.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) ATP-synt_10 PF05176.14 GAM41430.1 - 2.9e-83 279.0 0.0 3.6e-83 278.7 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.8 GAM41431.1 - 2.4e-14 53.4 0.1 2.4e-14 53.4 0.1 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.6 GAM41431.1 - 0.0088 14.8 6.1 0.013 14.2 6.1 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 STAT_alpha PF01017.20 GAM41431.1 - 0.12 12.3 3.5 0.18 11.7 1.4 2.2 1 1 2 3 3 3 0 STAT protein, all-alpha domain Syntaxin-6_N PF09177.11 GAM41431.1 - 0.33 11.5 4.5 0.94 10.1 1.8 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Surfac_D-trimer PF09006.11 GAM41431.1 - 0.48 10.4 1.6 2 8.4 0.1 2.5 2 1 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Snapin_Pallidin PF14712.6 GAM41431.1 - 1 9.9 7.9 0.31 11.5 4.3 2.0 2 0 0 2 2 2 0 Snapin/Pallidin FUSC PF04632.12 GAM41431.1 - 7.4 5.0 6.2 8.5 4.8 6.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ribosomal_L29 PF00831.23 GAM41432.1 - 5.9e-18 64.6 0.7 5.9e-18 64.6 0.7 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein Cortex-I_coil PF09304.10 GAM41432.1 - 0.028 14.6 2.3 0.042 14.1 0.8 1.8 2 0 0 2 2 2 0 Cortexillin I, coiled coil CorA PF01544.18 GAM41432.1 - 0.053 12.8 2.8 0.069 12.5 2.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Med16 PF11635.8 GAM41433.1 - 1e-112 377.5 0.4 2.5e-74 250.6 0.0 4.4 1 1 2 3 3 3 3 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 GAM41433.1 - 0.012 15.9 0.0 0.45 10.8 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SIR2 PF02146.17 GAM41434.1 - 6e-30 104.5 0.0 4.2e-29 101.7 0.0 2.3 2 1 0 2 2 2 1 Sir2 family ACP_PD PF04336.12 GAM41434.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase CBFD_NFYB_HMF PF00808.23 GAM41435.1 - 2.2e-06 27.8 0.0 4.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAM41435.1 - 0.0077 16.6 0.0 0.0077 16.6 0.0 2.7 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 Nop14 PF04147.12 GAM41435.1 - 0.66 8.1 26.8 0.9 7.7 26.8 1.3 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 GAM41435.1 - 3.2 7.6 22.3 4.5 7.2 22.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FancD2 PF14631.6 GAM41435.1 - 3.4 4.9 8.6 5.2 4.3 8.6 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease GN3L_Grn1 PF08701.11 GAM41436.1 - 9.4e-24 83.3 22.1 9.4e-24 83.3 22.1 2.0 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 GAM41436.1 - 1.5e-18 67.0 0.4 1.2e-13 51.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM41436.1 - 7.4e-07 29.2 0.0 7.9e-06 25.9 0.0 2.3 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 GAM41436.1 - 1.7e-05 24.4 0.0 0.00018 21.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAM41436.1 - 0.00064 19.8 6.4 0.45 10.5 0.1 3.9 2 2 1 3 3 3 1 Dynamin family AIG1 PF04548.16 GAM41436.1 - 0.00089 18.6 0.0 0.049 12.9 0.0 2.3 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 GAM41436.1 - 0.0042 16.7 6.3 0.35 10.4 0.1 3.4 3 2 0 3 3 3 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 GAM41436.1 - 0.011 14.8 0.0 0.011 14.8 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 GAM41436.1 - 0.085 13.4 0.0 0.085 13.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 GAM41436.1 - 0.81 10.0 0.0 0.81 10.0 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain HAD_2 PF13419.6 GAM41437.1 - 4.1e-14 53.0 0.0 5.3e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM41437.1 - 1.1e-05 25.8 0.1 9.7e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 GAM41438.1 - 8.4e-17 60.8 2.7 5.4e-16 58.2 2.4 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 GAM41438.1 - 6.8e-05 22.7 0.8 6.8e-05 22.7 0.8 2.0 2 0 0 2 2 2 1 Homeobox KN domain DUF4638 PF15472.6 GAM41438.1 - 0.13 12.0 8.2 0.23 11.2 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) MFS_1 PF07690.16 GAM41439.1 - 4.4e-43 147.5 26.3 4.4e-43 147.5 26.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM41439.1 - 9.5e-11 41.2 9.1 9.5e-11 41.2 9.1 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAM41439.1 - 2.1e-06 26.4 3.8 3.2e-06 25.8 3.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ank_2 PF12796.7 GAM41440.1 - 2.3e-157 512.0 5.0 5.7e-20 71.7 0.0 13.5 6 2 5 13 13 13 12 Ankyrin repeats (3 copies) Ank PF00023.30 GAM41440.1 - 2.5e-122 394.5 5.8 3.6e-06 27.2 0.0 25.8 26 0 0 26 26 26 21 Ankyrin repeat Ank_4 PF13637.6 GAM41440.1 - 7.9e-118 383.5 5.9 3.2e-10 40.3 0.0 18.7 12 6 8 20 20 20 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM41440.1 - 2e-106 334.9 5.5 7.5e-05 22.8 0.0 25.9 25 0 0 25 25 25 22 Ankyrin repeat Ank_5 PF13857.6 GAM41440.1 - 1.6e-104 340.6 18.1 1.1e-09 38.4 0.0 20.5 8 4 14 22 22 22 19 Ankyrin repeats (many copies) CRC_subunit PF08624.10 GAM41440.1 - 1.3e-51 174.5 0.1 2.4e-51 173.7 0.1 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit HET PF06985.11 GAM41440.1 - 2.6e-05 24.6 3.5 0.00046 20.5 0.2 2.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Mic1 PF07035.12 GAM41440.1 - 0.12 12.1 0.9 16 5.1 0.0 4.1 5 0 0 5 5 5 0 Colon cancer-associated protein Mic1-like SLD3 PF08639.10 GAM41441.1 - 6.8e-163 543.3 15.4 6.8e-163 543.3 15.4 2.0 2 0 0 2 2 2 1 DNA replication regulator SLD3 ING PF12998.7 GAM41441.1 - 1.8 9.2 6.2 0.53 10.9 1.9 2.3 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding SYF2 PF08231.12 GAM41441.1 - 9.5 6.6 9.9 0.4 11.1 1.0 2.3 2 0 0 2 2 2 0 SYF2 splicing factor APG6_N PF17675.1 GAM41441.1 - 9.8 6.7 9.4 0.44 11.1 0.6 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region S-AdoMet_synt_C PF02773.16 GAM41442.1 - 9.2e-67 223.3 0.4 3.4e-66 221.4 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 GAM41442.1 - 1e-43 148.0 0.5 2e-43 147.1 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 GAM41442.1 - 3.2e-43 146.8 0.0 6.5e-43 145.8 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain ATP_bind_1 PF03029.17 GAM41443.1 - 1.2e-74 251.1 0.0 7e-74 248.6 0.0 1.8 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 GAM41443.1 - 0.00014 21.8 0.0 0.00035 20.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM41443.1 - 0.0003 21.2 0.0 0.0012 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain CLP1_P PF16575.5 GAM41443.1 - 0.00055 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 GAM41443.1 - 0.0011 18.8 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAM41443.1 - 0.0012 19.3 0.0 0.0033 17.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 GAM41443.1 - 0.0014 17.7 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 GAM41443.1 - 0.0021 18.3 0.0 0.0045 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAM41443.1 - 0.0022 18.5 0.0 0.0044 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM41443.1 - 0.0025 18.2 0.0 0.031 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAM41443.1 - 0.0062 16.9 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 GAM41443.1 - 0.0068 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 GAM41443.1 - 0.011 16.3 0.0 0.035 14.6 0.0 1.8 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 GAM41443.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 GAM41443.1 - 0.013 15.2 0.0 0.032 13.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAM41443.1 - 0.014 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 GAM41443.1 - 0.021 14.8 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 GAM41443.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 NTPase Sigma54_activat PF00158.26 GAM41443.1 - 0.034 13.8 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 GAM41443.1 - 0.034 14.0 0.2 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 GAM41443.1 - 0.035 13.8 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 GAM41443.1 - 0.037 14.2 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GAM41443.1 - 0.045 12.9 0.1 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.18 GAM41443.1 - 0.045 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Septin SRP54 PF00448.22 GAM41443.1 - 0.047 13.3 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 GAM41443.1 - 0.048 13.7 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 GAM41443.1 - 0.051 13.2 0.1 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 GAM41443.1 - 0.063 12.5 0.0 0.063 12.5 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain Thymidylate_kin PF02223.17 GAM41443.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Thymidylate kinase GTP_EFTU PF00009.27 GAM41443.1 - 0.074 12.6 0.0 5.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATPase PF06745.13 GAM41443.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_31 PF13614.6 GAM41443.1 - 0.097 12.6 0.0 6 6.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 GAM41443.1 - 0.1 12.3 0.0 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 GAM41443.1 - 0.14 11.9 0.1 0.31 10.7 0.0 1.5 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 GAM41443.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Apq12 PF12716.7 GAM41444.1 - 1.1e-19 70.1 16.5 1.1e-19 70.1 16.5 1.6 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis Prefoldin_2 PF01920.20 GAM41445.1 - 4.5e-22 78.0 2.8 5.4e-22 77.8 2.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit CCDC-167 PF15188.6 GAM41445.1 - 0.0047 17.2 0.9 0.0088 16.4 0.9 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 FlxA PF14282.6 GAM41445.1 - 0.014 15.3 8.7 0.93 9.5 3.9 2.3 2 0 0 2 2 2 0 FlxA-like protein Fib_alpha PF08702.10 GAM41445.1 - 0.017 15.3 4.6 0.096 12.9 0.3 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Swi5 PF07061.11 GAM41445.1 - 0.017 15.2 8.4 0.5 10.5 1.4 2.1 2 0 0 2 2 2 0 Swi5 SMODS PF18144.1 GAM41445.1 - 0.018 15.2 0.5 0.023 14.9 0.5 1.1 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain DUF4200 PF13863.6 GAM41445.1 - 0.031 14.7 3.3 0.51 10.7 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Mito_carr PF00153.27 GAM41445.1 - 0.049 13.6 0.1 0.098 12.6 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial carrier protein T6PP_N PF18572.1 GAM41445.1 - 0.1 12.4 3.7 0.41 10.5 3.7 1.9 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF5082 PF16888.5 GAM41445.1 - 0.11 12.8 6.0 5.6 7.3 4.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Syntaxin-6_N PF09177.11 GAM41445.1 - 0.17 12.4 2.7 0.52 10.9 2.7 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Spc24 PF08286.11 GAM41445.1 - 0.18 12.0 3.2 1.4 9.2 0.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ZapB PF06005.12 GAM41445.1 - 0.2 12.1 0.3 0.2 12.1 0.3 2.2 2 1 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 GAM41445.1 - 0.88 10.2 6.1 71 4.1 6.1 2.1 1 1 0 1 1 1 0 Initiation control protein YabA SlyX PF04102.12 GAM41445.1 - 2 9.1 8.0 9.7 6.9 3.0 2.3 2 0 0 2 2 2 0 SlyX USP8_interact PF08941.10 GAM41445.1 - 3.2 7.5 5.3 1.7 8.4 2.1 1.8 1 1 0 2 2 2 0 USP8 interacting NACHT_N PF17100.5 GAM41446.1 - 6.6e-53 179.8 0.8 1.7e-52 178.5 0.8 1.7 1 1 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 GAM41446.1 - 2.6e-09 37.5 1.9 0.00095 19.9 1.1 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat NACHT PF05729.12 GAM41446.1 - 0.00015 21.7 0.0 0.0003 20.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 GAM41446.1 - 0.00027 21.2 0.1 0.0084 16.4 0.0 3.0 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM41446.1 - 0.0082 14.8 0.3 0.22 10.1 0.0 2.4 3 0 0 3 3 3 1 Nucleoporin Nup120/160 AAA_16 PF13191.6 GAM41446.1 - 0.012 16.1 0.0 0.15 12.4 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain eIF2A PF08662.11 GAM41446.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAM41446.1 - 0.035 13.1 0.0 0.72 8.8 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 GAM41446.1 - 0.035 12.6 0.0 0.059 11.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain NmrA PF05368.13 GAM41447.1 - 1.6e-31 109.7 0.7 2e-31 109.4 0.7 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM41447.1 - 3.5e-13 49.9 0.0 5.9e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAM41447.1 - 3.7e-05 24.0 0.8 0.01 16.1 0.0 2.4 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 GAM41447.1 - 0.023 14.6 0.3 0.076 12.9 0.0 1.8 2 0 0 2 2 2 0 KR domain GARS_N PF02844.15 GAM41447.1 - 0.1 13.4 0.0 0.2 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain MTH865 PF07747.11 GAM41447.1 - 0.15 11.9 0.3 0.6 9.9 0.1 2.1 2 0 0 2 2 2 0 MTH865-like family Fungal_trans PF04082.18 GAM41448.1 - 0.00027 20.1 0.2 0.00063 18.9 0.1 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain F_actin_bind PF08919.10 GAM41448.1 - 0.055 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 F-actin binding Mito_carr PF00153.27 GAM41450.1 - 3e-53 177.7 2.9 5.5e-19 67.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AAA PF00004.29 GAM41451.1 - 0.00053 20.4 0.0 0.0046 17.4 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TFIIA PF03153.13 GAM41451.1 - 0.021 14.9 12.5 0.023 14.7 12.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DIOX_N PF14226.6 GAM41454.1 - 2.7e-27 95.9 0.1 4.9e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM41454.1 - 3.3e-16 59.6 0.0 5.6e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cytochrom_B559a PF00284.20 GAM41454.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit Rcd1 PF04078.13 GAM41455.1 - 2.4e-126 420.3 3.1 2.9e-126 420.0 3.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TAF4 PF05236.14 GAM41455.1 - 0.0075 16.1 6.5 0.012 15.4 6.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DAGK_cat PF00781.24 GAM41455.1 - 0.11 12.1 1.8 0.27 10.8 1.8 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain baeRF_family10 PF18854.1 GAM41455.1 - 0.17 12.1 13.2 1.3 9.3 9.8 2.5 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 Miff PF05644.11 GAM41455.1 - 0.35 10.4 5.7 0.54 9.8 5.7 1.3 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff EPL1 PF10513.9 GAM41455.1 - 0.74 10.2 4.1 1.1 9.7 4.1 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like TFIIA PF03153.13 GAM41455.1 - 1.3 9.0 19.6 1.6 8.6 19.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PHD PF00628.29 GAM41456.1 - 2.1e-07 30.7 12.9 4.8e-07 29.6 12.9 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAM41456.1 - 0.24 11.0 12.4 0.056 13.0 8.7 1.8 2 0 0 2 2 2 0 PHD-finger Sld5 PF05916.11 GAM41457.1 - 3.1e-13 50.1 0.0 7e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 GINS complex protein HMG_box PF00505.19 GAM41457.1 - 8.4e-11 42.1 0.6 1.8e-10 41.1 0.6 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 GAM41457.1 - 0.016 14.5 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Sulfate_transp PF00916.20 GAM41458.1 - 4.6e-59 200.1 23.3 7.5e-59 199.4 23.3 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 GAM41458.1 - 4e-14 52.4 0.0 8e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 GAM41458.1 - 1.1e-12 47.6 0.2 2e-12 46.7 0.2 1.4 1 0 0 1 1 1 1 STAS domain Dicty_CAR PF05462.11 GAM41458.1 - 0.013 14.7 1.0 0.024 13.8 1.0 1.4 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor PH_6 PF15406.6 GAM41459.1 - 7.4e-38 129.3 5.1 7.4e-38 129.3 5.1 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 GAM41459.1 - 1.1e-06 29.0 0.0 4.5e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 PH domain PH_4 PF15404.6 GAM41459.1 - 0.18 11.6 0.0 0.18 11.6 0.0 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain bZIP_2 PF07716.15 GAM41460.1 - 1.4e-06 28.2 7.6 3.2e-06 27.1 7.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAM41460.1 - 1.8e-05 24.7 6.2 3.9e-05 23.7 6.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor PKcGMP_CC PF16808.5 GAM41460.1 - 0.041 13.7 0.4 0.091 12.6 0.4 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Abhydrolase_1 PF00561.20 GAM41461.1 - 4.5e-15 56.0 0.1 4.7e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold PNP_UDP_1 PF01048.20 GAM41461.1 - 2.7e-11 43.2 0.3 8e-11 41.6 0.3 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Abhydrolase_6 PF12697.7 GAM41461.1 - 0.00027 21.6 0.0 0.00084 20.0 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM41461.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 GAM41461.1 - 0.085 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative esterase Cu_amine_oxid PF01179.20 GAM41462.1 - 5.5e-159 529.5 0.2 6.8e-159 529.2 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 GAM41462.1 - 3.5e-09 36.8 0.1 7.4e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 GAM41462.1 - 6.5e-06 26.5 0.0 1.9e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Asn_synthase PF00733.21 GAM41463.1 - 5.8e-15 55.8 0.1 5.6e-05 23.0 0.0 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 GAM41463.1 - 2.8e-06 27.3 0.0 2.2e-05 24.4 0.0 2.4 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAM41463.1 - 0.087 13.0 0.0 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferase domain GATase_4 PF13230.6 GAM41463.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferases class-II NAD_synthase PF02540.17 GAM41463.1 - 0.17 10.9 0.0 0.47 9.5 0.0 1.6 2 0 0 2 2 2 0 NAD synthase VPS9 PF02204.18 GAM41464.1 - 1e-20 73.9 0.0 1.9e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 GAM41464.1 - 3.2e-15 56.2 0.2 1e-14 54.5 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 GAM41464.1 - 1.9e-09 37.0 0.1 2.8e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 CUE domain Amelin PF05111.12 GAM41465.1 - 0.056 12.6 0.8 0.06 12.5 0.8 1.0 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) SURF4 PF02077.15 GAM41467.1 - 2.9e-97 325.4 8.5 3.3e-97 325.3 8.5 1.0 1 0 0 1 1 1 1 SURF4 family UPF0139 PF03669.13 GAM41467.1 - 0.068 13.0 1.4 0.25 11.2 0.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0139) HR_lesion PF05514.11 GAM41467.1 - 1.7 8.9 9.2 1 9.6 2.0 2.9 3 1 0 3 3 3 0 HR-like lesion-inducing DUF4191 PF13829.6 GAM41467.1 - 6.3 6.1 7.7 3.6 6.9 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) AA_permease PF00324.21 GAM41468.1 - 1e-95 321.1 37.6 2.3e-88 296.9 22.0 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 GAM41468.1 - 2.2e-21 76.2 31.4 3.2e-21 75.7 30.4 1.7 1 1 1 2 2 2 1 Amino acid permease FMO-like PF00743.19 GAM41468.1 - 2.9e-06 26.0 0.0 0.11 10.9 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAM41468.1 - 1.7e-05 24.2 0.0 7.9e-05 22.0 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM41468.1 - 0.0011 18.3 0.0 0.025 13.8 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM41468.1 - 0.0031 16.7 0.0 0.0086 15.3 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAM41468.1 - 0.006 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAM41468.1 - 0.0071 16.5 0.1 0.081 13.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Spore_YtrH PF14034.6 GAM41468.1 - 0.84 9.8 6.7 1 9.6 4.5 2.1 2 0 0 2 2 2 0 Sporulation protein YtrH HAD_2 PF13419.6 GAM41469.1 - 5e-14 52.8 0.0 7.3e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM41469.1 - 2.2e-10 41.2 0.0 1.6e-09 38.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM41469.1 - 0.0002 21.4 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like PC4 PF02229.16 GAM41469.1 - 0.074 12.7 0.8 0.78 9.4 0.1 2.4 2 0 0 2 2 2 0 Transcriptional Coactivator p15 (PC4) HTH_3 PF01381.22 GAM41469.1 - 0.14 12.2 0.0 0.71 10.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix Amidase PF01425.21 GAM41470.1 - 2.9e-77 260.5 2.0 8e-76 255.8 2.0 2.9 1 1 0 1 1 1 1 Amidase ICL PF00463.21 GAM41471.1 - 1.3e-115 386.9 0.0 1.6e-115 386.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 GAM41471.1 - 2.1e-07 30.6 0.0 4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF2935 PF11155.8 GAM41471.1 - 0.095 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Fungal_trans PF04082.18 GAM41472.1 - 1.2e-05 24.5 0.0 0.0089 15.1 0.0 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 GAM41474.1 - 1.7e-07 30.4 0.9 2.2e-07 30.1 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain VIT1 PF01988.19 GAM41475.1 - 1.5e-60 204.7 3.5 1.9e-60 204.4 3.5 1.1 1 0 0 1 1 1 1 VIT family DUF4202 PF13875.6 GAM41476.1 - 1.4e-80 269.6 0.9 1.5e-80 269.5 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) ClpS PF02617.17 GAM41476.1 - 0.098 12.5 0.3 5 7.0 0.0 2.5 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS HTH_29 PF13551.6 GAM41476.1 - 0.11 12.5 0.1 0.42 10.7 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn helix Hydrolase PF00702.26 GAM41477.1 - 0.00021 21.6 0.0 0.0007 19.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAM41477.1 - 0.00031 20.9 0.0 0.013 15.6 0.0 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Rox3 PF08633.10 GAM41478.1 - 1.1e-62 212.0 0.5 1.1e-62 212.0 0.5 1.7 2 0 0 2 2 2 1 Rox3 mediator complex subunit PBP1_TM PF14812.6 GAM41478.1 - 0.019 15.3 0.0 0.058 13.8 0.0 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hamartin PF04388.12 GAM41478.1 - 6.2 5.4 10.1 8.6 4.9 10.1 1.2 1 0 0 1 1 1 0 Hamartin protein MFS_1 PF07690.16 GAM41479.1 - 2.9e-30 105.4 22.1 4.2e-30 104.9 22.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1180 PF06679.12 GAM41479.1 - 0.053 13.9 0.0 0.089 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PEP_mutase PF13714.6 GAM41480.1 - 8.3e-50 169.5 0.1 1.1e-49 169.1 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 GAM41480.1 - 7.3e-12 44.5 0.2 1.1e-11 44.0 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 GAM41480.1 - 8.8e-06 25.3 0.0 0.0017 17.8 0.0 2.1 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase Fungal_trans PF04082.18 GAM41481.1 - 4.7e-18 65.2 0.1 7.3e-18 64.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM41481.1 - 7.7e-08 32.3 8.0 7.7e-08 32.3 8.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM41482.1 - 4.9e-14 52.0 0.0 7.7e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain OCD_Mu_crystall PF02423.15 GAM41483.1 - 8.8e-13 47.9 0.0 1.4e-05 24.2 0.0 2.1 1 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 GAM41483.1 - 0.02 14.9 0.0 6.1 6.9 0.0 2.6 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3479 PF11965.8 GAM41483.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) IU_nuc_hydro PF01156.19 GAM41485.1 - 1.7e-58 198.6 0.0 2.5e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Transketolase_C PF02780.20 GAM41485.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain DUF4820 PF16091.5 GAM41486.1 - 0.016 14.6 0.6 0.023 14.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Hamartin PF04388.12 GAM41486.1 - 1.5 7.4 8.4 1.7 7.2 8.4 1.0 1 0 0 1 1 1 0 Hamartin protein Tmemb_cc2 PF10267.9 GAM41486.1 - 1.9 7.5 3.4 2.1 7.4 3.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Med3 PF11593.8 GAM41486.1 - 2.2 7.4 17.9 2.8 7.1 17.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GREB1 PF15782.5 GAM41486.1 - 5.5 4.0 8.1 6.1 3.8 8.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HLH PF00010.26 GAM41487.1 - 3.7e-14 52.4 0.6 7.5e-14 51.4 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Adeno_E3_14_5 PF04834.12 GAM41487.1 - 0.14 12.7 1.7 2.3 8.8 0.0 3.0 3 0 0 3 3 3 0 Early E3 14.5 kDa protein WH2 PF02205.20 GAM41489.1 - 1.5e-10 40.5 0.3 2.3e-10 40.0 0.3 1.3 1 0 0 1 1 1 1 WH2 motif MPS2 PF17060.5 GAM41490.1 - 0.055 12.7 0.1 0.09 12.0 0.1 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 Ribosomal_L1 PF00687.21 GAM41491.1 - 8e-45 153.1 0.1 9.2e-45 152.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.18 GAM41491.1 - 0.028 13.1 0.1 0.039 12.7 0.1 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family SieB PF14163.6 GAM41492.1 - 0.043 13.3 0.7 0.1 12.1 0.7 1.6 1 0 0 1 1 1 0 Super-infection exclusion protein B CorA PF01544.18 GAM41492.1 - 0.35 10.2 5.7 1.1 8.5 0.4 2.7 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Arf PF00025.21 GAM41493.1 - 4.4e-79 264.0 0.5 5.2e-79 263.7 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAM41493.1 - 3e-14 53.3 0.0 4.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAM41493.1 - 3.9e-14 52.5 0.0 4.9e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 GAM41493.1 - 2.2e-13 50.2 0.0 2.4e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GAM41493.1 - 2.2e-13 50.1 1.3 1.9e-09 37.1 0.5 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 GAM41493.1 - 2.5e-10 40.1 0.0 3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM41493.1 - 4.2e-06 26.8 0.0 6.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 GAM41493.1 - 0.01 15.1 0.5 0.028 13.7 0.1 1.7 1 1 0 2 2 2 0 6-phosphofructo-2-kinase Choline_kinase PF01633.20 GAM41494.1 - 1.2e-46 159.0 0.0 2e-45 155.0 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 GAM41494.1 - 7.8e-09 35.8 0.1 3e-08 33.9 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family MFS_1 PF07690.16 GAM41495.1 - 4.7e-37 127.7 30.3 1e-36 126.6 25.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM41495.1 - 1.6e-07 30.6 14.7 6.1e-05 22.1 0.3 2.8 1 1 1 2 2 2 2 Sugar (and other) transporter Sugar_tr PF00083.24 GAM41496.1 - 2.3e-91 306.9 18.2 2.7e-91 306.7 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM41496.1 - 4.9e-33 114.5 40.9 1.8e-25 89.7 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LMBR1 PF04791.16 GAM41496.1 - 0.14 11.0 5.8 0.076 11.9 3.8 1.4 2 0 0 2 2 2 0 LMBR1-like membrane protein Sod_Cu PF00080.20 GAM41497.1 - 9e-12 45.4 0.0 1.3e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Pyr_redox_3 PF13738.6 GAM41498.1 - 2.4e-26 92.7 0.0 2.1e-24 86.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAM41498.1 - 1.3e-22 80.0 0.0 5.7e-21 74.5 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAM41498.1 - 2.5e-20 72.9 0.0 1.7e-16 60.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM41498.1 - 5.1e-15 55.4 0.3 1.4e-11 44.2 0.3 3.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 GAM41498.1 - 7.6e-09 36.0 0.1 0.024 15.2 0.1 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 GAM41498.1 - 1.1e-08 34.6 0.3 0.0028 17.0 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 GAM41498.1 - 2.4e-08 33.6 0.3 0.00038 19.8 0.1 3.1 2 1 1 3 3 3 2 FAD binding domain NAD_binding_9 PF13454.6 GAM41498.1 - 9.3e-07 29.0 0.2 0.37 10.8 0.0 3.9 3 1 1 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAM41498.1 - 2e-06 27.9 0.0 6.3e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 GAM41498.1 - 3.5e-05 23.5 0.0 0.16 11.6 0.0 2.8 2 1 1 3 3 3 2 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 GAM41498.1 - 5.1e-05 23.7 0.0 0.015 15.7 0.1 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 GAM41498.1 - 8.6e-05 21.8 0.0 0.0085 15.2 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.14 GAM41498.1 - 0.00019 20.3 0.0 0.052 12.2 0.0 3.0 4 0 0 4 4 4 1 HI0933-like protein 3HCDH_N PF02737.18 GAM41498.1 - 0.00021 21.2 0.0 0.073 12.9 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GAM41498.1 - 0.00034 21.1 0.0 3.3 8.4 0.0 3.5 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.22 GAM41498.1 - 0.00034 19.8 0.0 0.26 10.3 0.0 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A Shikimate_DH PF01488.20 GAM41498.1 - 0.00047 20.2 0.0 0.21 11.6 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 GAM41498.1 - 0.00056 19.5 0.0 0.0031 17.1 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 GAM41498.1 - 0.00088 19.5 0.2 0.87 9.9 0.0 2.9 3 0 0 3 3 2 1 TrkA-N domain DAO PF01266.24 GAM41498.1 - 0.0016 18.1 2.1 0.98 8.9 0.0 3.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAM41498.1 - 0.0026 17.1 0.0 0.57 9.4 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 GAM41498.1 - 0.0041 16.3 0.0 0.063 12.3 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_2 PF03446.15 GAM41498.1 - 0.0093 16.1 0.1 2.1 8.5 0.1 2.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Thi4 PF01946.17 GAM41498.1 - 0.011 14.9 0.1 1.6 7.9 0.0 3.2 4 0 0 4 4 4 0 Thi4 family XdhC_C PF13478.6 GAM41498.1 - 0.033 14.7 0.0 0.7 10.4 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_Gly3P_dh_N PF01210.23 GAM41498.1 - 0.12 12.4 0.0 0.96 9.4 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ELFV_dehydrog PF00208.21 GAM41498.1 - 0.35 10.5 0.9 0.52 10.0 0.2 1.6 2 0 0 2 2 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF3405 PF11885.8 GAM41499.1 - 9.4e-228 757.0 0.6 1.1e-227 756.7 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) MFS_1 PF07690.16 GAM41500.1 - 2.3e-40 138.6 48.9 2.3e-40 138.6 48.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM41500.1 - 1.7e-13 49.9 13.8 1.7e-13 49.9 13.8 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM41500.1 - 3.7e-12 45.9 5.4 3.7e-12 45.9 5.4 3.2 3 1 1 4 4 4 2 Sugar (and other) transporter DUF836 PF05768.14 GAM41501.1 - 5.4e-15 55.6 0.1 6.3e-15 55.4 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 GAM41501.1 - 0.00096 19.3 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin CHORD PF04968.12 GAM41502.1 - 3.3e-52 175.0 19.6 7.1e-28 97.1 6.7 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 GAM41502.1 - 1.4e-13 51.7 0.0 2.1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 CS domain Pheromone PF08015.11 GAM41502.1 - 0.45 11.6 4.2 1.5 9.9 4.2 2.0 1 1 0 1 1 1 0 Fungal mating-type pheromone BTK PF00779.19 GAM41502.1 - 1.6 8.6 13.4 6.1 6.8 1.1 3.6 2 1 0 2 2 2 0 BTK motif adh_short_C2 PF13561.6 GAM41503.1 - 7.8e-51 172.9 0.1 1e-50 172.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM41503.1 - 9.1e-48 162.3 0.0 1.2e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM41503.1 - 2.3e-11 43.9 0.0 4e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM41503.1 - 0.00088 18.8 0.1 0.0034 16.9 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 GAM41503.1 - 0.11 12.4 0.5 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 14-3-3 PF00244.20 GAM41504.1 - 2.6e-07 30.4 0.1 4.7e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 14-3-3 protein DUF3237 PF11578.8 GAM41505.1 - 2.6e-30 105.2 0.0 3e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) adh_short PF00106.25 GAM41506.1 - 1.5e-15 57.2 0.0 7.8e-15 54.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAM41506.1 - 3.4e-06 27.1 0.1 6.2e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 GAM41506.1 - 4.1e-06 26.5 0.0 7.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 GAM41506.1 - 0.1 12.0 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Metallophos PF00149.28 GAM41507.1 - 1.6e-08 35.3 1.3 2.8e-08 34.5 1.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SR-25 PF10500.9 GAM41507.1 - 0.0042 16.7 11.9 0.041 13.5 4.4 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein ArAE_2_N PF10337.9 GAM41508.1 - 2.6e-13 49.9 2.1 1.7e-10 40.6 0.1 2.6 2 0 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 GAM41508.1 - 2.9e-10 40.4 6.8 2.9e-10 40.4 6.8 2.7 3 1 0 3 3 3 1 Fusaric acid resistance protein-like DUF4770 PF15994.5 GAM41508.1 - 0.11 12.8 1.5 0.31 11.3 1.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Tim54 PF11711.8 GAM41508.1 - 0.25 10.1 3.9 0.34 9.7 2.4 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF4834 PF16118.5 GAM41508.1 - 0.29 12.1 2.2 74 4.4 1.6 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Acyl-CoA_dh_1 PF00441.24 GAM41509.1 - 3.9e-34 118.0 0.4 5.4e-34 117.6 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAM41509.1 - 1.5e-22 79.6 0.0 2.8e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAM41509.1 - 2e-12 47.8 0.0 1.4e-11 45.0 0.0 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAM41509.1 - 9.3e-08 32.4 0.2 1.6e-07 31.7 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CrtC PF07143.11 GAM41509.1 - 0.18 12.5 0.0 0.28 11.8 0.0 1.3 1 0 0 1 1 1 0 CrtC N-terminal lipocalin domain EMP24_GP25L PF01105.24 GAM41510.1 - 3.4e-48 164.0 0.5 3.9e-48 163.8 0.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Filament PF00038.21 GAM41511.1 - 0.0047 16.6 11.2 0.0047 16.6 11.2 5.1 4 1 1 5 5 5 3 Intermediate filament protein PAM2 PF07145.15 GAM41511.1 - 0.087 12.5 0.0 0.087 12.5 0.0 4.5 5 0 0 5 5 5 0 Ataxin-2 C-terminal region Spc7 PF08317.11 GAM41511.1 - 0.14 11.0 79.3 0.054 12.4 16.1 5.1 2 1 3 5 5 5 0 Spc7 kinetochore protein FliD_C PF07195.12 GAM41511.1 - 0.84 9.0 14.8 0.17 11.3 0.8 3.9 3 2 1 4 4 4 0 Flagellar hook-associated protein 2 C-terminus Pox_A_type_inc PF04508.12 GAM41511.1 - 1.7 8.6 5.3 15 5.6 3.3 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat adh_short PF00106.25 GAM41512.1 - 2.8e-19 69.4 0.0 4.6e-19 68.6 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM41512.1 - 9.2e-13 48.3 0.0 1.5e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM41512.1 - 3.2e-09 36.9 0.0 5.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM41512.1 - 4.8e-06 26.2 0.0 6.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 GAM41512.1 - 0.00026 20.3 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 GAM41512.1 - 0.00032 21.0 0.0 0.00048 20.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 GAM41512.1 - 0.00032 20.2 0.0 0.00043 19.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAM41512.1 - 0.0032 16.6 0.3 0.0072 15.5 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain 3HCDH_N PF02737.18 GAM41512.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 GAM41512.1 - 0.059 13.3 0.4 0.15 11.9 0.4 1.9 1 1 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAM41512.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 GAM41512.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sas10 PF09368.10 GAM41513.1 - 5.3e-28 97.3 10.4 5.3e-28 97.3 10.4 4.4 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 GAM41513.1 - 1.4e-12 48.0 4.5 2.4e-12 47.3 0.0 3.3 2 1 0 2 2 2 1 Sas10/Utp3/C1D family MutS_V PF00488.21 GAM41514.1 - 3.2e-43 148.0 0.0 6.2e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAM41514.1 - 2.3e-17 63.8 0.1 4e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 GAM41514.1 - 0.012 15.9 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV AAA PF00004.29 GAM41514.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 GAM41515.1 - 3.4e-44 151.0 2.0 3.6e-43 147.6 0.0 3.0 4 0 0 4 4 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAM41515.1 - 9.1e-36 121.9 2.8 9.1e-36 121.9 2.8 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 GAM41515.1 - 1.2e-25 89.4 0.2 3.9e-25 87.7 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 GAM41515.1 - 2.5e-19 70.0 0.9 1.2e-10 41.9 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAM41515.1 - 9.8e-12 45.0 0.0 4.3e-07 30.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM41515.1 - 1.3e-08 35.4 6.2 0.00023 21.6 0.1 3.9 3 2 0 4 4 3 2 AAA ATPase domain Sigma54_activat PF00158.26 GAM41515.1 - 1e-06 28.6 0.3 0.00096 18.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 GAM41515.1 - 2.1e-06 28.0 3.6 0.02 15.1 0.0 3.9 3 3 0 3 3 3 2 AAA domain TniB PF05621.11 GAM41515.1 - 3.2e-06 26.7 0.1 0.0048 16.3 0.0 3.6 2 1 0 2 2 2 1 Bacterial TniB protein AAA_14 PF13173.6 GAM41515.1 - 7.1e-06 26.1 0.0 0.025 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 GAM41515.1 - 3.2e-05 23.9 0.0 0.074 13.0 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_7 PF12775.7 GAM41515.1 - 3.5e-05 23.4 0.1 0.14 11.7 0.0 2.7 3 0 0 3 3 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAM41515.1 - 0.00025 20.9 0.0 0.45 10.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 GAM41515.1 - 0.00049 20.4 0.5 0.06 13.6 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_24 PF13479.6 GAM41515.1 - 0.00067 19.4 0.0 0.8 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAM41515.1 - 0.0013 19.3 0.9 2.9 8.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain SRP54 PF00448.22 GAM41515.1 - 0.0014 18.3 0.1 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ABC_tran PF00005.27 GAM41515.1 - 0.0018 18.8 2.3 0.41 11.1 0.0 3.3 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.21 GAM41515.1 - 0.0022 17.4 0.2 2.1 7.7 0.1 2.9 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GAM41515.1 - 0.003 17.9 0.0 2.2 8.7 0.0 3.0 2 0 0 2 2 2 1 RNA helicase ResIII PF04851.15 GAM41515.1 - 0.003 17.6 0.0 6.1 6.8 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Roc PF08477.13 GAM41515.1 - 0.0067 16.6 0.1 2.7 8.2 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 GAM41515.1 - 0.0074 16.3 0.1 6 6.9 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 GAM41515.1 - 0.0075 16.0 0.0 0.41 10.4 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 GAM41515.1 - 0.0082 16.5 0.7 0.23 11.8 0.1 3.0 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 GAM41515.1 - 0.0095 15.9 9.5 3.2 7.6 0.0 4.6 3 2 1 4 4 4 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 GAM41515.1 - 0.011 15.6 2.0 3.2 7.7 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase DUF815 PF05673.13 GAM41515.1 - 0.031 13.5 0.6 0.4 9.8 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_21 PF13304.6 GAM41515.1 - 0.036 13.9 2.0 0.49 10.2 0.0 3.1 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 GAM41515.1 - 0.036 14.2 0.1 13 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 GAM41515.1 - 0.04 12.8 0.1 0.85 8.5 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 GAM41515.1 - 0.057 12.7 0.0 6.7 5.9 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 GAM41515.1 - 0.058 13.1 4.7 0.12 12.1 0.0 3.4 3 1 1 4 4 3 0 AAA domain UvrD-helicase PF00580.21 GAM41515.1 - 0.07 12.6 3.1 0.64 9.5 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain PhoH PF02562.16 GAM41515.1 - 0.077 12.4 0.2 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 GAM41515.1 - 0.078 12.5 0.6 1.1 8.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAM41515.1 - 0.15 11.8 0.2 6.4 6.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rootletin PF15035.6 GAM41515.1 - 0.34 10.9 9.5 0.69 9.9 9.5 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DNA_topoisoIV PF00521.20 GAM41515.1 - 0.43 9.4 5.1 0.73 8.7 5.1 1.3 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A UPF0242 PF06785.11 GAM41515.1 - 0.96 9.5 8.6 2.2 8.3 8.6 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus EF1_GNE PF00736.19 GAM41516.1 - 1.6e-33 114.7 2.9 3.2e-33 113.7 2.9 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 GAM41516.1 - 7.6e-09 35.9 6.9 7.6e-09 35.9 6.9 2.5 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 GAM41516.1 - 0.0026 17.9 0.2 0.0061 16.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM41516.1 - 0.0044 17.2 1.4 0.012 15.8 0.1 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Thioesterase PF00975.20 GAM41516.1 - 0.015 15.4 0.2 0.023 14.8 0.2 1.2 1 0 0 1 1 1 0 Thioesterase domain MMgT PF10270.9 GAM41517.1 - 4.2e-32 110.5 0.0 5.1e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter UQ_con PF00179.26 GAM41519.1 - 4.6e-28 97.6 0.0 5e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM41519.1 - 0.0083 15.8 0.0 0.0097 15.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAM41519.1 - 0.05 13.9 0.0 0.056 13.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain RNB PF00773.19 GAM41521.1 - 3.7e-90 302.6 0.1 8e-90 301.5 0.0 1.6 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 GAM41521.1 - 1.8e-26 92.0 0.1 7.1e-26 90.1 0.0 2.1 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 GAM41521.1 - 4.9e-25 87.7 0.0 1.5e-24 86.1 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 GAM41521.1 - 8.2e-05 22.7 0.0 0.027 14.6 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 GAM41521.1 - 9.3e-05 22.2 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain GLE1 PF07817.13 GAM41522.1 - 2.2e-46 158.1 0.0 3.2e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 GLE1-like protein Caldesmon PF02029.15 GAM41522.1 - 0.04 12.7 48.3 0.054 12.2 48.3 1.1 1 0 0 1 1 1 0 Caldesmon MFS_1 PF07690.16 GAM41523.1 - 4.9e-27 94.8 31.9 4.9e-27 94.8 31.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM41523.1 - 0.0016 17.4 15.0 0.0016 17.4 15.0 3.3 3 0 0 3 3 3 2 Sugar (and other) transporter DUF3464 PF11947.8 GAM41523.1 - 0.26 11.1 1.9 0.68 9.7 1.9 1.8 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 Amidase PF01425.21 GAM41524.1 - 3.3e-81 273.6 0.0 6.8e-81 272.5 0.0 1.5 1 1 0 1 1 1 1 Amidase Oxidored_FMN PF00724.20 GAM41525.1 - 3.2e-39 135.2 0.0 4.3e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans_2 PF11951.8 GAM41526.1 - 2.6e-14 52.9 3.7 3.4e-14 52.5 3.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MIT PF04212.18 GAM41526.1 - 0.25 11.4 0.9 0.64 10.1 0.3 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF3425 PF11905.8 GAM41527.1 - 1.8e-13 50.5 0.2 4.1e-13 49.4 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 GAM41527.1 - 0.0014 18.7 17.6 0.021 14.9 17.6 2.2 1 1 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 GAM41527.1 - 0.011 16.1 0.1 0.024 14.9 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family LCD1 PF09798.9 GAM41527.1 - 0.38 9.2 0.8 0.51 8.8 0.8 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein bZIP_2 PF07716.15 GAM41527.1 - 2 8.6 19.5 2.3e+02 1.9 19.5 2.3 1 1 0 1 1 1 0 Basic region leucine zipper FAD_binding_3 PF01494.19 GAM41528.1 - 9.1e-16 58.0 0.0 1.2e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FA_hydroxylase PF04116.13 GAM41529.1 - 8.2e-18 65.0 3.6 8.2e-18 65.0 3.6 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.19 GAM41530.1 - 3.5e-39 133.8 0.3 3.5e-39 133.8 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e GNAT_acetyltr_2 PF13718.6 GAM41530.1 - 0.038 13.4 0.2 0.063 12.7 0.2 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 ORC5_C PF14630.6 GAM41530.1 - 0.05 13.1 0.4 0.074 12.5 0.4 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Proteasom_Rpn13 PF04683.13 GAM41531.1 - 8.5e-27 93.5 0.0 1.4e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 GAM41531.1 - 1e-10 41.7 1.4 3.2e-09 37.0 1.4 2.4 1 1 0 1 1 1 1 UCH-binding domain Ion_trans PF00520.31 GAM41532.1 - 1.1e-118 394.8 85.9 1.5e-42 145.6 5.4 4.9 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 GAM41532.1 - 0.00074 19.2 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 GAM41532.1 - 0.021 14.3 0.0 0.06 12.9 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 GAM41532.1 - 0.037 13.9 0.0 0.17 11.9 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain JSRP PF15312.6 GAM41532.1 - 0.14 12.0 0.0 0.57 10.1 0.0 2.0 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein DUF2149 PF09919.9 GAM41532.1 - 8.3 6.7 7.8 2.7 8.3 0.1 3.9 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2149) Cellulase PF00150.18 GAM41533.1 - 1.4e-16 60.8 5.9 1.8e-16 60.5 5.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SET PF00856.28 GAM41535.1 - 2.3e-17 63.9 0.0 8.2e-17 62.1 0.0 2.0 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 GAM41535.1 - 3.6e-14 53.3 2.1 3.6e-14 53.3 2.1 2.2 2 1 0 2 2 2 1 Pre-SET motif Metallothio_PEC PF02068.16 GAM41535.1 - 0.98 9.8 9.9 0.37 11.2 1.4 3.3 3 0 0 3 3 3 0 Plant PEC family metallothionein Pkinase PF00069.25 GAM41536.1 - 2.2e-70 237.1 0.0 3.1e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM41536.1 - 2.8e-40 138.2 0.0 6.6e-40 137.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 GAM41536.1 - 8.9e-17 60.6 0.4 1.6e-16 59.8 0.4 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 GAM41536.1 - 1.3e-05 24.7 0.0 0.00024 20.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAM41536.1 - 1.9e-05 24.1 0.0 3.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAM41536.1 - 0.00011 21.3 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAM41536.1 - 0.0011 18.9 0.1 0.0077 16.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GAM41536.1 - 0.068 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 GAM41536.1 - 0.087 12.4 0.2 0.22 11.1 0.2 1.6 1 1 0 1 1 1 0 RIO1 family ABC1 PF03109.16 GAM41536.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 ABC1 family DUF1604 PF07713.13 GAM41537.1 - 2.8e-44 148.8 2.7 1.1e-43 146.9 2.7 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 GAM41537.1 - 8e-07 28.9 1.7 2e-06 27.6 1.7 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAM41537.1 - 0.0093 16.0 0.1 0.054 13.6 0.0 2.5 2 0 0 2 2 2 1 G-patch domain UBD PF16455.5 GAM41538.1 - 6.5e-42 142.0 0.0 1.2e-41 141.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 GAM41538.1 - 1e-05 25.2 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAM41538.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAM41538.1 - 0.0021 18.6 0.7 0.0065 17.0 0.0 2.0 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain Shisa PF13908.6 GAM41538.1 - 1.9 8.7 4.1 4.2 7.6 1.7 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator SMN PF06003.12 GAM41538.1 - 5.1 6.3 8.3 0.25 10.6 1.5 2.0 2 1 0 2 2 2 0 Survival motor neuron protein (SMN) Nop52 PF05997.12 GAM41539.1 - 5.7e-55 186.4 0.9 7.2e-40 137.1 0.4 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 RNA_pol_Rpc4 PF05132.14 GAM41539.1 - 0.032 14.6 0.2 0.032 14.6 0.2 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 TssD PF17642.1 GAM41539.1 - 0.063 13.1 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Hemolysin coregulated protein Hcp (TssD) NOT2_3_5 PF04153.18 GAM41539.1 - 0.066 13.3 1.2 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family DUF2201_N PF13203.6 GAM41539.1 - 0.094 12.3 0.2 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain LRIF1 PF15741.5 GAM41539.1 - 0.13 10.8 5.3 0.2 10.2 5.3 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Connexin PF00029.19 GAM41539.1 - 0.13 12.0 0.3 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 Connexin AP3D1 PF06375.11 GAM41539.1 - 0.82 9.9 17.5 0.97 9.6 9.8 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 TRAP_alpha PF03896.16 GAM41539.1 - 2 7.6 6.1 5.1 6.2 1.1 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 GAM41539.1 - 2.6 6.7 3.8 4.1 6.1 3.8 1.3 1 0 0 1 1 1 0 Presenilin Vac_ImportDeg PF09783.9 GAM41540.1 - 1.3e-65 220.2 3.6 1.7e-65 219.8 3.6 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.14 GAM41541.1 - 4.4e-73 244.1 0.1 5e-73 243.9 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.20 GAM41542.1 - 1.9e-98 330.3 11.1 3e-98 329.7 11.1 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 GAM41542.1 - 4.8e-58 195.0 0.3 1.2e-57 193.8 0.3 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 GAM41542.1 - 1.2e-56 190.2 0.0 3.5e-56 188.7 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 GAM41542.1 - 2.3e-15 57.0 8.0 7.1e-11 42.4 0.1 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM41542.1 - 1.4e-10 41.4 3.0 8.4e-06 26.1 0.0 4.6 1 1 3 4 4 4 3 HEAT repeats Coatomer_g_Cpla PF16381.5 GAM41542.1 - 0.00013 22.1 0.0 0.00061 19.9 0.0 2.2 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_EZ PF13513.6 GAM41542.1 - 0.00016 22.1 0.4 0.048 14.2 0.0 4.4 3 1 1 4 4 4 2 HEAT-like repeat API5 PF05918.11 GAM41542.1 - 0.00044 19.2 3.5 0.026 13.3 0.0 2.9 3 0 0 3 3 3 2 Apoptosis inhibitory protein 5 (API5) HEAT PF02985.22 GAM41542.1 - 0.00047 20.2 1.3 0.55 10.6 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat AP4E_app_platf PF14807.6 GAM41542.1 - 0.013 15.8 0.2 0.05 14.0 0.2 2.0 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform DUF5578 PF17741.1 GAM41542.1 - 0.023 14.1 2.3 2.4 7.5 0.0 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5578) HNF-1A_C PF04813.12 GAM41542.1 - 0.061 14.1 0.0 0.24 12.2 0.0 2.0 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Arm PF00514.23 GAM41542.1 - 0.17 12.0 5.1 0.86 9.7 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DAGK_cat PF00781.24 GAM41543.1 - 3.4e-25 88.1 0.0 5.3e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 GAM41544.1 - 1.6e-66 224.4 0.0 3.4e-66 223.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM41544.1 - 7.8e-36 123.7 0.0 3.2e-25 88.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAM41544.1 - 0.0001 21.7 0.7 0.0049 16.2 0.6 2.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 GAM41544.1 - 0.0017 18.3 0.0 0.0053 16.7 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAM41544.1 - 0.0025 16.7 0.0 0.0049 15.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 GAM41544.1 - 0.011 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FERM_f0 PF16511.5 GAM41544.1 - 0.065 13.5 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM FtsX_ECD PF18075.1 GAM41544.1 - 0.07 13.8 0.0 0.31 11.7 0.0 2.2 1 0 0 1 1 1 0 FtsX extracellular domain Ammonium_transp PF00909.21 GAM41545.1 - 1.7e-120 402.4 29.0 1.9e-120 402.2 29.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 GAM41545.1 - 0.7 9.9 6.0 0.35 10.9 1.2 2.9 2 0 0 2 2 2 0 Bacteriophage P21 holin S RRM_1 PF00076.22 GAM41546.1 - 1.9e-15 56.4 0.0 3.9e-06 26.6 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tubulin PF00091.25 GAM41547.1 - 3.7e-68 229.6 0.0 6.5e-68 228.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAM41547.1 - 1e-41 142.0 0.0 1.7e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GAM41547.1 - 2.7e-05 24.5 0.0 7.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 GAM41547.1 - 0.0027 17.0 0.0 0.024 13.9 0.0 2.0 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 GAM41547.1 - 0.0033 17.1 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain TrmK PF04816.12 GAM41547.1 - 0.2 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Cation_ATPase_C PF00689.21 GAM41549.1 - 2.6e-44 151.1 15.7 5.9e-44 150.0 10.3 2.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAM41549.1 - 2.8e-38 131.2 1.0 2.8e-38 131.2 1.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAM41549.1 - 3.8e-22 78.2 0.0 8.4e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM41549.1 - 1.2e-17 64.9 0.0 3.3e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM41549.1 - 1.7e-08 34.0 0.2 8.6e-08 31.8 0.1 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM41549.1 - 4.1e-05 23.4 2.5 0.00019 21.2 1.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RskA PF10099.9 GAM41549.1 - 0.021 15.1 4.1 0.26 11.6 0.2 3.5 3 1 0 3 3 3 0 Anti-sigma-K factor rskA HD PF01966.22 GAM41550.1 - 8e-05 22.9 0.0 0.00012 22.3 0.0 1.2 1 0 0 1 1 1 1 HD domain Nup84_Nup100 PF04121.13 GAM41551.1 - 2.8e-147 491.9 10.6 2.8e-147 491.9 10.6 1.7 2 0 0 2 2 2 1 Nuclear pore protein 84 / 107 Aldo_ket_red PF00248.21 GAM41551.1 - 0.0022 17.3 0.1 0.16 11.2 0.0 2.4 2 0 0 2 2 2 1 Aldo/keto reductase family CDC45 PF02724.14 GAM41551.1 - 0.28 9.4 23.4 0.1 10.8 20.1 1.9 2 0 0 2 2 2 0 CDC45-like protein Zip PF02535.22 GAM41551.1 - 0.61 9.3 5.8 0.91 8.7 5.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.8 GAM41551.1 - 3.3 6.4 11.5 5.8 5.6 11.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.12 GAM41551.1 - 5.4 5.1 37.8 0.77 7.9 32.1 2.0 2 0 0 2 2 2 0 Nop14-like family Rad60-SLD PF11976.8 GAM41552.1 - 2.9e-20 71.8 0.3 3.4e-20 71.7 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAM41552.1 - 2.3e-11 43.3 0.1 2.6e-11 43.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Jak1_Phl PF17887.1 GAM41553.1 - 6.7 6.7 11.6 0.063 13.3 1.1 2.4 2 1 0 2 2 2 0 Jak1 pleckstrin homology-like domain MFS_1 PF07690.16 GAM41554.1 - 1.7e-31 109.4 44.8 1.7e-31 109.4 44.8 2.9 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM41554.1 - 9e-10 38.0 10.9 9e-10 38.0 10.9 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter Ligase_CoA PF00549.19 GAM41555.1 - 3.1e-37 127.7 1.3 1.7e-18 66.9 0.1 2.4 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 GAM41555.1 - 8.5e-18 64.8 0.2 3.4e-17 62.9 0.2 2.1 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 GAM41555.1 - 2.8e-11 43.4 0.0 1.2e-07 31.6 0.0 2.6 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 GAM41555.1 - 0.0012 19.3 0.3 0.01 16.3 0.1 2.5 3 0 0 3 3 3 1 CoA binding domain ATP-grasp_2 PF08442.10 GAM41555.1 - 0.039 13.5 0.0 0.17 11.4 0.0 2.1 1 1 0 1 1 1 0 ATP-grasp domain V-ATPase_C PF03223.15 GAM41556.1 - 3.9e-122 408.2 0.0 4.7e-122 408.0 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C 4HBT PF03061.22 GAM41556.1 - 6.7e-10 39.2 0.0 3.2e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 Thioesterase superfamily APS_kinase PF01583.20 GAM41557.1 - 9.8e-72 240.0 0.0 1.2e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 GAM41557.1 - 4.3e-06 26.9 0.0 7.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAM41557.1 - 7.2e-05 23.3 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM41557.1 - 0.0058 17.0 0.0 0.0065 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 GAM41557.1 - 0.0059 16.1 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 NCD2 PF04905.13 GAM41557.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) G-alpha PF00503.20 GAM41557.1 - 0.049 12.8 0.1 0.15 11.1 0.1 1.7 2 1 0 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.6 GAM41557.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain 6PF2K PF01591.18 GAM41557.1 - 0.12 11.6 0.1 0.2 10.9 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase MFS_1 PF07690.16 GAM41559.1 - 8.4e-27 94.0 29.2 2.5e-26 92.5 25.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Colicin_K PF17500.2 GAM41559.1 - 0.33 11.5 2.5 1.4 9.5 0.1 3.0 2 1 2 4 4 4 0 Colicin-K LapA_dom PF06305.11 GAM41559.1 - 3 7.7 4.5 2.1 8.2 0.0 3.0 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain GCV_T PF01571.21 GAM41560.1 - 1.5e-75 253.9 0.0 1.9e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 GAM41560.1 - 1.5e-14 53.7 0.0 3.5e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Aa_trans PF01490.18 GAM41561.1 - 0.019 13.7 3.6 0.022 13.5 3.6 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein Aa_trans PF01490.18 GAM41562.1 - 2.3e-20 72.7 22.6 2.8e-20 72.4 22.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PSI_PsaF PF02507.15 GAM41562.1 - 0.98 9.2 3.0 1.8 8.4 0.2 2.4 3 0 0 3 3 3 0 Photosystem I reaction centre subunit III AAT PF03417.16 GAM41563.1 - 5.7e-26 91.6 0.0 7e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Penicil_amidase PF01804.18 GAM41563.1 - 0.004 16.2 0.0 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 Penicillin amidase BCNT PF07572.12 GAM41563.1 - 1.8 8.7 7.1 11 6.2 1.8 3.9 4 1 0 4 4 4 0 Bucentaur or craniofacial development Fungal_trans PF04082.18 GAM41564.1 - 4.6e-25 88.2 1.2 1e-24 87.0 0.9 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 GAM41564.1 - 4.3e-14 52.2 29.5 1.2e-09 37.6 24.3 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Zn_clus PF00172.18 GAM41564.1 - 1.4e-07 31.6 4.7 2.8e-07 30.6 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2070 PF09843.9 GAM41564.1 - 0.011 14.1 0.5 0.017 13.5 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MFS_1_like PF12832.7 GAM41564.1 - 1.8 7.4 11.9 3.1 6.6 11.9 1.4 1 0 0 1 1 1 0 MFS_1 like family DAO PF01266.24 GAM41565.1 - 1.8e-26 93.6 0.0 2e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 GAM41565.1 - 0.0071 15.8 0.0 0.027 13.9 0.0 1.9 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 GAM41565.1 - 0.029 14.6 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 GAM41565.1 - 0.091 13.2 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 GAM41565.1 - 0.12 12.7 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAM41565.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 GAM41565.1 - 0.18 11.0 0.2 0.35 10.1 0.1 1.5 2 0 0 2 2 2 0 Thi4 family DUF3425 PF11905.8 GAM41566.1 - 3e-20 72.4 1.3 6.1e-20 71.4 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 GAM41566.1 - 1.5 9.0 10.2 2.6 8.2 10.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor Aldo_ket_red PF00248.21 GAM41567.1 - 1.8e-74 250.6 0.0 2.1e-74 250.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CBF PF03914.17 GAM41568.1 - 2.4e-57 193.7 0.5 2.4e-57 193.7 0.5 3.6 4 0 0 4 4 4 1 CBF/Mak21 family HGTP_anticodon PF03129.20 GAM41569.1 - 4.3e-11 42.8 0.0 8.8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAM41569.1 - 2.4e-07 30.9 0.0 5.3e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) MciZ PF13072.6 GAM41569.1 - 0.16 11.8 0.7 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 Mother cell inhibitor of FtsZ zinc_ribbon_13 PF09855.9 GAM41569.1 - 0.19 11.9 0.6 3 8.1 0.0 2.8 3 0 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Rubredoxin PF00301.20 GAM41569.1 - 0.81 9.8 2.9 1.2 9.2 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin Prefoldin PF02996.17 GAM41570.1 - 4.5e-26 91.1 1.1 5.6e-26 90.8 1.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 GAM41570.1 - 0.00054 19.9 2.3 0.012 15.6 0.6 2.1 2 0 0 2 2 2 1 Prefoldin subunit UvsW PF11637.8 GAM41570.1 - 0.0021 18.1 0.5 0.0091 16.1 0.4 2.1 2 1 0 2 2 2 1 ATP-dependant DNA helicase UvsW Fib_alpha PF08702.10 GAM41570.1 - 0.0044 17.2 3.6 1 9.6 0.7 2.1 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 GAM41570.1 - 0.011 16.0 0.4 0.17 12.2 0.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dynamitin PF04912.14 GAM41570.1 - 0.02 14.2 0.3 0.026 13.9 0.3 1.1 1 0 0 1 1 1 0 Dynamitin PHM7_cyt PF14703.6 GAM41570.1 - 0.032 14.5 1.0 0.069 13.4 1.0 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Tektin PF03148.14 GAM41570.1 - 0.04 12.7 1.3 2.4 6.8 0.2 2.0 2 0 0 2 2 2 0 Tektin family Snapin_Pallidin PF14712.6 GAM41570.1 - 0.047 14.1 1.1 3.2 8.2 0.1 2.2 2 0 0 2 2 2 0 Snapin/Pallidin Erf4 PF10256.9 GAM41570.1 - 0.075 13.1 0.1 3.1 7.9 0.1 2.4 1 1 1 3 3 3 0 Golgin subfamily A member 7/ERF4 family Serine_rich PF08824.10 GAM41570.1 - 0.085 12.9 0.2 0.74 9.8 0.1 2.0 2 0 0 2 2 2 0 Serine rich protein interaction domain DUF4164 PF13747.6 GAM41570.1 - 0.095 13.0 0.8 14 6.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) CLZ PF16526.5 GAM41570.1 - 0.1 13.0 2.8 1 9.8 0.4 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4315 PF14193.6 GAM41570.1 - 0.15 12.0 3.7 0.16 12.0 0.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) BST2 PF16716.5 GAM41570.1 - 0.21 12.2 3.0 6.1 7.5 0.2 2.5 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 YvrJ PF12841.7 GAM41570.1 - 0.37 10.3 1.7 9.9 5.8 0.1 2.3 2 0 0 2 2 2 0 YvrJ protein family TMF_DNA_bd PF12329.8 GAM41570.1 - 0.5 10.4 5.0 4.2 7.4 1.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RLAN PF14401.6 GAM41571.1 - 0.023 14.3 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain AAA PF00004.29 GAM41572.1 - 1.7e-15 57.6 0.0 3.2e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 GAM41572.1 - 2e-13 50.3 1.2 3e-12 46.5 0.5 2.6 1 1 1 2 2 2 1 AAA lid domain AAA_16 PF13191.6 GAM41572.1 - 3.5e-10 40.5 0.0 3.3e-09 37.4 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM41572.1 - 1.2e-09 38.6 0.0 3.6e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 GAM41572.1 - 6.9e-06 25.9 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 GAM41572.1 - 0.0018 18.7 0.0 0.0039 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAM41572.1 - 0.0072 16.6 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAM41572.1 - 0.011 15.6 0.0 0.011 15.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 GAM41572.1 - 0.014 15.4 0.0 0.056 13.4 0.0 2.1 2 1 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 GAM41572.1 - 0.039 14.5 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GAM41572.1 - 0.05 13.5 0.0 1.2 9.0 0.0 2.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 GAM41572.1 - 0.051 14.0 0.0 0.24 11.8 0.0 2.2 2 0 0 2 2 1 0 RNA helicase DUF2075 PF09848.9 GAM41572.1 - 0.063 12.5 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 GAM41572.1 - 0.084 13.0 0.0 0.49 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 GAM41572.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase KAP_NTPase PF07693.14 GAM41572.1 - 0.11 11.7 0.0 0.32 10.2 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain UvrD-helicase PF00580.21 GAM41572.1 - 0.11 12.0 0.4 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain TsaE PF02367.17 GAM41572.1 - 0.17 11.9 0.0 0.48 10.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Oxidored_FMN PF00724.20 GAM41573.1 - 7.4e-40 137.2 0.0 1.3e-39 136.4 0.0 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family WD40 PF00400.32 GAM41574.1 - 3.2e-43 144.8 12.0 5.5e-09 36.5 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM41574.1 - 4.2e-06 27.0 0.9 4.3 7.7 0.0 5.2 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM41574.1 - 0.033 13.5 0.0 0.088 12.1 0.0 1.7 2 0 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 GAM41574.1 - 0.037 12.7 2.1 23 3.4 0.1 4.1 1 1 2 5 5 5 0 Nucleoporin Nup120/160 Ank_2 PF12796.7 GAM41575.1 - 3.1e-42 143.1 5.5 2.1e-14 53.8 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM41575.1 - 1.2e-33 114.7 1.7 3.2e-09 36.9 0.0 4.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM41575.1 - 2.8e-31 107.5 2.6 1.2e-08 35.3 0.0 5.3 1 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM41575.1 - 6.8e-29 96.7 1.5 9e-05 22.6 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 GAM41575.1 - 2e-22 78.6 3.9 8e-05 22.9 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat TMF_TATA_bd PF12325.8 GAM41576.1 - 2e-41 140.8 13.7 2e-41 140.8 13.7 7.1 3 1 5 8 8 8 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 GAM41576.1 - 4.3e-21 74.7 16.3 4.3e-21 74.7 16.3 9.8 7 2 4 11 11 11 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 GAM41576.1 - 9.3e-06 26.0 5.3 9.3e-06 26.0 5.3 5.8 3 2 2 5 5 5 1 Autophagy protein 16 (ATG16) BST2 PF16716.5 GAM41576.1 - 0.012 16.1 9.7 0.012 16.1 9.7 7.6 5 2 3 8 8 8 0 Bone marrow stromal antigen 2 Golgin_A5 PF09787.9 GAM41576.1 - 5.6 6.3 94.9 0.71 9.3 35.6 4.6 3 2 1 4 4 4 0 Golgin subfamily A member 5 Laminin_II PF06009.12 GAM41576.1 - 5.9 6.9 61.9 0.032 14.3 3.2 6.6 2 2 4 7 7 7 0 Laminin Domain II Spc7 PF08317.11 GAM41576.1 - 6.6 5.5 101.4 0.023 13.6 20.3 5.3 2 1 2 4 4 4 0 Spc7 kinetochore protein DUF3584 PF12128.8 GAM41576.1 - 8.8 3.7 93.8 0.23 8.9 8.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) DUF948 PF06103.11 GAM41576.1 - 9 6.6 33.6 2.1 8.7 2.9 6.6 3 3 2 5 5 5 0 Bacterial protein of unknown function (DUF948) V-ATPase_H_N PF03224.14 GAM41577.1 - 1.2e-77 261.3 0.2 2.3e-77 260.4 0.0 1.6 2 0 0 2 2 2 1 V-ATPase subunit H Fungal_trans_2 PF11951.8 GAM41577.1 - 1e-58 199.0 0.6 2.4e-58 197.8 0.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain V-ATPase_H_C PF11698.8 GAM41577.1 - 6.1e-35 119.9 0.0 1.9e-34 118.3 0.0 1.8 1 0 0 1 1 1 1 V-ATPase subunit H Zn_clus PF00172.18 GAM41577.1 - 5.1e-07 29.7 10.8 8.1e-07 29.1 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ceramidase PF05875.12 GAM41578.1 - 1.1e-95 320.1 6.5 1.5e-95 319.6 6.5 1.1 1 0 0 1 1 1 1 Ceramidase Spc7 PF08317.11 GAM41578.1 - 0.0012 17.8 10.7 0.0012 17.8 10.7 4.9 5 0 0 5 5 5 2 Spc7 kinetochore protein DUF4094 PF13334.6 GAM41578.1 - 0.13 12.7 0.1 0.13 12.7 0.1 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4094) MatP_C PF17414.2 GAM41578.1 - 0.16 12.2 3.6 0.57 10.4 1.9 3.0 2 0 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain Peptidase_U4 PF03419.13 GAM41578.1 - 2.8 7.1 8.7 8.4 5.6 6.9 2.4 2 1 0 2 2 2 0 Sporulation factor SpoIIGA Filament PF00038.21 GAM41578.1 - 4.8 6.7 63.4 0.25 10.9 13.2 5.4 4 1 0 4 4 4 0 Intermediate filament protein DUF2407_C PF13373.6 GAM41578.1 - 5.7 7.1 12.6 0.15 12.2 2.0 3.4 3 0 0 3 3 3 0 DUF2407 C-terminal domain Abhydrolase_6 PF12697.7 GAM41579.1 - 6e-14 53.2 0.1 9.5e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM41579.1 - 9.5e-07 28.3 0.0 1.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM41579.1 - 0.00034 20.4 0.0 0.0014 18.3 0.0 2.0 3 0 0 3 3 3 1 alpha/beta hydrolase fold GMC_oxred_N PF00732.19 GAM41580.1 - 1.1e-62 212.1 0.0 1.4e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM41580.1 - 3.6e-32 111.8 0.0 9.1e-32 110.6 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAM41580.1 - 1.5e-06 27.5 0.2 0.0092 15.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAM41580.1 - 0.00018 21.6 0.2 0.00051 20.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM41580.1 - 0.00064 19.1 0.0 0.91 8.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM41580.1 - 0.0016 17.7 0.3 0.0068 15.7 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 GAM41580.1 - 0.0029 16.7 0.1 0.0046 16.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 GAM41580.1 - 0.0047 16.5 0.8 0.012 15.2 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM41580.1 - 0.081 12.1 0.1 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM41580.1 - 0.085 11.5 0.0 0.17 10.6 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein RTT107_BRCT_5 PF16770.5 GAM41581.1 - 2.3e-35 120.5 0.0 1e-31 108.8 0.0 3.8 4 0 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 GAM41581.1 - 1.4e-34 117.8 0.4 1.2e-20 73.2 0.1 6.5 6 1 0 6 6 6 3 twin BRCT domain BRCT PF00533.26 GAM41581.1 - 5.1e-30 103.7 0.0 2.3e-08 34.3 0.0 6.9 7 1 0 7 7 7 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAM41581.1 - 2.4e-24 85.5 0.0 8.2e-06 26.1 0.0 6.4 6 0 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 GAM41581.1 - 1.1e-10 41.6 0.0 0.00068 19.9 0.0 4.4 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 GAM41581.1 - 0.0084 16.2 0.0 4.8 7.3 0.0 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain HNF-1_N PF04814.13 GAM41581.1 - 0.76 10.4 3.2 1.6 9.3 3.2 1.5 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Mcm10 PF09332.11 GAM41581.1 - 6.7 6.0 12.7 10 5.4 12.7 1.2 1 0 0 1 1 1 0 Mcm10 replication factor ESCRT-II PF05871.12 GAM41582.1 - 1.3e-40 138.9 0.4 1.7e-40 138.5 0.4 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit Methyltransf_4 PF02390.17 GAM41583.1 - 2.1e-43 147.8 0.6 1.3e-28 99.7 0.0 3.1 2 1 1 3 3 3 3 Putative methyltransferase DUF913 PF06025.12 GAM41583.1 - 0.0014 17.7 0.1 0.041 12.9 0.0 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) Methyltransf_25 PF13649.6 GAM41583.1 - 0.0045 17.7 0.1 0.036 14.8 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain DUF4527 PF15030.6 GAM41583.1 - 0.0047 16.4 0.0 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4527) Methyltransf_32 PF13679.6 GAM41583.1 - 0.0093 16.0 0.0 0.024 14.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAM41583.1 - 0.012 15.2 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.12 GAM41583.1 - 0.021 15.6 0.2 0.18 12.6 0.0 2.5 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 GAM41583.1 - 0.081 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF4820 PF16091.5 GAM41583.1 - 0.37 10.1 2.3 29 3.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) LIM PF00412.22 GAM41584.1 - 1.5e-27 95.6 20.6 2.6e-10 40.3 3.8 3.7 3 1 0 3 3 3 3 LIM domain Zn_ribbon_recom PF13408.6 GAM41584.1 - 0.12 12.9 0.1 0.12 12.9 0.1 2.8 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain Paired_CXXCH_1 PF09699.10 GAM41584.1 - 0.91 9.3 5.8 0.8 9.5 0.2 3.3 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) RNB PF00773.19 GAM41585.1 - 1.1e-99 333.9 0.0 1.7e-99 333.3 0.0 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 GAM41585.1 - 1.9e-27 95.0 1.6 2.5e-27 94.7 0.3 2.0 2 0 0 2 2 2 1 S1 domain OB_Dis3 PF17849.1 GAM41585.1 - 6.3e-21 74.2 0.0 3.5e-20 71.8 0.0 2.4 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 GAM41585.1 - 1.8e-11 44.4 0.1 4.7e-11 43.1 0.1 1.7 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 GAM41585.1 - 2.6e-06 27.5 0.0 1.4e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 Cold shock domain Rrp44_CSD1 PF17216.3 GAM41585.1 - 3.9e-05 23.4 2.8 5.1e-05 23.0 0.9 2.2 1 1 1 2 2 2 1 Rrp44-like cold shock domain DUF3352 PF11832.8 GAM41585.1 - 0.079 11.6 0.4 0.12 11.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) CN_hydrolase PF00795.22 GAM41586.1 - 7e-57 192.7 0.1 7.8e-57 192.6 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ESSS PF10183.9 GAM41587.1 - 2.9e-21 75.7 0.0 3.5e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Dna2 PF08696.11 GAM41588.1 - 1.3e-68 230.8 0.7 3.1e-68 229.6 0.7 1.7 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 GAM41588.1 - 1.6e-55 187.9 0.0 4.1e-55 186.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAM41588.1 - 9.7e-33 114.0 2.1 1.3e-16 61.2 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 GAM41588.1 - 3.5e-14 53.0 0.0 7.9e-14 51.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM41588.1 - 1.1e-12 48.5 0.5 4.6e-12 46.5 0.1 2.3 3 0 0 3 3 2 1 AAA domain Cas_Cas4 PF01930.17 GAM41588.1 - 1.8e-10 41.1 0.6 1.7e-08 34.7 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 GAM41588.1 - 3.6e-08 33.6 0.2 6.6e-08 32.8 0.2 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 GAM41588.1 - 6.3e-06 26.1 3.7 0.25 11.1 0.1 3.7 3 1 1 4 4 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 GAM41588.1 - 9.1e-05 22.4 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 GAM41588.1 - 0.00087 18.9 0.2 0.00087 18.9 0.2 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 GAM41588.1 - 0.0012 18.6 0.1 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PIF1 PF05970.14 GAM41588.1 - 0.0022 17.2 0.3 0.012 14.8 0.3 2.0 1 1 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 GAM41588.1 - 0.0044 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 GAM41588.1 - 0.005 16.9 1.9 0.0083 16.2 0.2 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CbiA PF01656.23 GAM41588.1 - 0.0069 16.4 0.1 0.03 14.4 0.1 2.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Csa1 PF06023.12 GAM41588.1 - 0.0081 15.5 0.6 0.031 13.7 0.6 1.9 1 1 0 1 1 1 1 CRISPR-associated exonuclease Csa1 cobW PF02492.19 GAM41588.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 GAM41588.1 - 0.029 13.9 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 GAM41588.1 - 0.033 13.8 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 GAM41588.1 - 0.035 14.2 0.7 0.11 12.6 0.3 2.0 2 0 0 2 2 1 0 Helicase HerA, central domain MobB PF03205.14 GAM41588.1 - 0.036 13.9 0.1 0.091 12.7 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.9 GAM41588.1 - 0.046 12.9 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 GAM41588.1 - 0.05 13.9 0.2 1.6 9.0 0.0 3.2 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAM41588.1 - 0.062 13.2 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 GAM41588.1 - 0.069 13.7 0.0 0.22 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAM41588.1 - 0.13 12.7 0.0 0.41 11.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAM41588.1 - 0.14 12.2 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.6 GAM41588.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain RuvB_N PF05496.12 GAM41588.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MeaB PF03308.16 GAM41588.1 - 0.17 10.8 0.0 0.36 9.8 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SOG2 PF10428.9 GAM41589.1 - 1.8 7.7 6.2 2.6 7.2 6.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Ribonuc_P_40 PF08584.11 GAM41590.1 - 5.5e-57 193.2 0.0 5.4e-56 190.0 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.32 GAM41591.1 - 1.1e-26 92.5 5.7 2.9e-05 24.7 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM41591.1 - 1.2e-19 70.4 0.0 0.00029 21.1 0.0 5.8 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 GAM41591.1 - 2.4e-09 36.2 0.0 0.00029 19.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 GAM41591.1 - 1.7e-05 24.8 0.0 0.22 11.4 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAM41591.1 - 0.0063 15.2 1.3 0.11 11.1 0.3 2.1 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 GAM41591.1 - 0.02 14.0 0.0 0.28 10.2 0.0 2.4 2 2 1 3 3 3 0 Coatomer WD associated region Ge1_WD40 PF16529.5 GAM41591.1 - 0.089 11.7 0.0 7.1 5.5 0.0 3.3 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 GAM41591.1 - 0.16 10.8 0.0 0.36 9.7 0.0 1.5 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Fungal_trans PF04082.18 GAM41592.1 - 2e-14 53.3 0.0 4.6e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM41592.1 - 1.7e-09 37.6 9.6 3.1e-09 36.8 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L2_C PF03947.18 GAM41593.1 - 8.6e-53 177.9 4.0 1.9e-51 173.5 3.4 2.7 2 1 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 GAM41593.1 - 1.2e-27 95.6 0.7 2.8e-27 94.5 0.7 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.23 GAM41594.1 - 7.7e-47 158.2 0.0 5.5e-45 152.2 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAM41594.1 - 6e-35 119.9 0.1 1.3e-34 118.8 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain UPF0020 PF01170.18 GAM41595.1 - 3.9e-10 39.7 0.1 5.3e-08 32.8 0.1 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 GAM41595.1 - 0.00014 21.2 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.18 GAM41595.1 - 0.0042 16.8 0.1 0.02 14.6 0.0 1.9 2 0 0 2 2 2 1 DNA methylase MethyltransfD12 PF02086.15 GAM41595.1 - 0.12 12.0 0.1 0.42 10.2 0.1 1.9 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Zn_ribbon_17 PF17120.5 GAM41595.1 - 1.4 8.6 4.5 2.4 7.8 4.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type SIR2 PF02146.17 GAM41596.1 - 2.9e-59 200.0 0.0 4.1e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 GAM41596.1 - 0.00014 21.6 0.1 0.00037 20.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 GAM41596.1 - 0.0012 18.5 0.1 0.44 10.3 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain TPR_19 PF14559.6 GAM41597.1 - 7.8e-11 42.3 5.4 8e-05 23.1 0.3 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM41597.1 - 1.1e-10 41.6 2.6 1.2e-05 25.5 0.3 4.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM41597.1 - 2.7e-08 33.4 1.0 0.00065 19.7 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM41597.1 - 6e-08 32.2 1.8 0.0064 16.5 0.0 5.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM41597.1 - 3.8e-07 30.4 8.9 1.1 10.3 0.1 6.1 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM41597.1 - 1.8e-06 28.5 0.7 0.046 14.4 0.1 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM41597.1 - 1.4e-05 24.6 1.7 0.0032 16.9 0.1 2.6 2 1 0 2 2 2 2 MalT-like TPR region TPR_9 PF13371.6 GAM41597.1 - 3.6e-05 23.8 9.2 0.1 12.7 0.2 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM41597.1 - 3.7e-05 23.3 0.0 0.11 12.4 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAM41597.1 - 0.00048 19.7 0.2 0.01 15.5 0.0 3.2 4 0 0 4 4 4 1 TPR repeat TPR_10 PF13374.6 GAM41597.1 - 0.0006 19.6 0.6 15 5.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAM41597.1 - 0.0073 16.6 0.7 2.4e+02 2.5 0.1 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM41597.1 - 0.0079 16.8 4.5 46 4.9 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM41597.1 - 0.0095 15.9 0.4 6.9 6.9 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAM41597.1 - 0.087 12.3 3.4 0.37 10.3 0.1 3.1 3 0 0 3 3 3 0 SHNi-TPR Cwf_Cwc_15 PF04889.12 GAM41597.1 - 4.6 6.9 12.9 7.9 6.1 12.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RWD PF05773.22 GAM41598.1 - 4.4e-24 85.0 1.7 4.4e-24 85.0 1.7 1.6 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 GAM41598.1 - 0.12 12.9 17.8 0.48 10.9 17.5 2.2 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 Zip PF02535.22 GAM41598.1 - 0.13 11.4 1.5 0.15 11.2 1.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Smg4_UPF3 PF03467.15 GAM41598.1 - 0.19 11.7 6.7 0.32 11.0 6.7 1.4 1 0 0 1 1 1 0 Smg-4/UPF3 family Presenilin PF01080.17 GAM41598.1 - 3.1 6.5 5.4 3.8 6.2 5.4 1.1 1 0 0 1 1 1 0 Presenilin DASH_Spc19 PF08287.11 GAM41598.1 - 9.7 6.1 17.0 0.18 11.7 2.7 2.2 1 1 1 2 2 2 0 Spc19 UQ_con PF00179.26 GAM41600.1 - 3.7e-20 72.0 0.0 4.2e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAM41600.1 - 0.012 15.9 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 0 RWD domain DCB PF16213.5 GAM41601.1 - 1.7e-40 138.5 3.4 1.7e-40 138.5 3.4 2.8 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 GAM41601.1 - 2.5e-37 128.2 11.5 3.1e-37 127.9 1.3 4.2 4 1 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 GAM41601.1 - 2.3e-22 79.0 5.4 3.3e-22 78.5 2.1 2.6 3 0 0 3 3 3 1 C-terminal region of Mon2 protein Ipi1_N PF12333.8 GAM41601.1 - 5.1e-05 23.8 1.1 5.6 7.6 0.0 5.0 4 0 0 4 4 4 2 Rix1 complex component involved in 60S ribosome maturation DUF1981 PF09324.10 GAM41601.1 - 0.00018 21.3 0.9 0.74 9.7 0.0 5.9 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Vps26 PF03643.15 GAM41602.1 - 2e-130 433.8 0.2 2.4e-130 433.5 0.2 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 GAM41602.1 - 0.00016 21.7 0.1 0.82 9.7 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Totivirus_coat PF05518.11 GAM41602.1 - 0.09 10.8 1.7 0.11 10.6 1.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein AAA_18 PF13238.6 GAM41603.1 - 6.6e-10 39.6 0.0 8.1e-09 36.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAM41603.1 - 5e-09 36.5 0.0 2.4e-08 34.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain SKI PF01202.22 GAM41603.1 - 9.3e-07 29.1 0.0 0.001 19.2 0.0 2.2 2 0 0 2 2 2 2 Shikimate kinase AAA_17 PF13207.6 GAM41603.1 - 2.9e-06 27.7 0.0 0.001 19.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 GAM41603.1 - 0.00015 21.6 0.0 0.00039 20.2 0.0 1.6 2 0 0 2 2 2 1 Cytidylate kinase dNK PF01712.19 GAM41603.1 - 0.00023 21.1 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_22 PF13401.6 GAM41603.1 - 0.00091 19.5 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAM41603.1 - 0.0018 18.7 0.0 0.0039 17.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM41603.1 - 0.0048 17.3 0.0 0.0069 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 GAM41603.1 - 0.0068 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 GAM41603.1 - 0.0079 15.9 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK PF00406.22 GAM41603.1 - 0.0086 16.2 0.1 0.87 9.7 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase RuvB_N PF05496.12 GAM41603.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 GAM41603.1 - 0.014 14.6 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 GAM41603.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 GAM41603.1 - 0.016 15.5 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAM41603.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 GAM41603.1 - 0.028 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 GAM41603.1 - 0.035 14.5 0.0 0.083 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 GAM41603.1 - 0.039 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 GAM41603.1 - 0.04 13.5 0.0 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 GAM41603.1 - 0.045 13.5 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain CoaE PF01121.20 GAM41603.1 - 0.048 13.3 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase APS_kinase PF01583.20 GAM41603.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 GAM41603.1 - 0.079 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 GAM41603.1 - 0.085 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAM41603.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.6 GAM41603.1 - 0.12 12.0 0.0 0.26 10.8 0.0 1.5 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 GAM41603.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 GAM41603.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.16 GAM41603.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.6 GAM41603.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain 2-oxoacid_dh PF00198.23 GAM41604.1 - 3.1e-79 265.7 0.5 4.5e-79 265.2 0.5 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAM41604.1 - 3.1e-14 52.5 0.0 9.3e-14 51.0 0.0 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 GAM41604.1 - 4.3e-12 46.2 0.6 1.2e-11 44.7 0.1 2.1 2 0 0 2 2 2 1 e3 binding domain PI-PLC-X PF00388.19 GAM41605.1 - 1.4e-11 44.1 0.0 2.2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L10 PF00466.20 GAM41606.1 - 0.0032 17.6 0.0 0.021 14.9 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L10 ATXN-1_C PF12547.8 GAM41606.1 - 1 9.8 6.0 2.6 8.4 0.3 2.7 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator Glycos_transf_3 PF00591.21 GAM41607.1 - 1.2e-53 182.3 0.0 3.6e-45 154.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 GAM41607.1 - 3.3e-06 26.8 0.5 6.4e-06 25.9 0.5 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.13 GAM41608.1 - 9.1e-17 60.4 1.0 1.2e-16 60.0 1.0 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 GAM41608.1 - 0.0021 18.0 1.5 0.011 15.7 1.5 2.0 1 1 0 1 1 1 1 zinc-ribbon domain zf_UBZ PF18439.1 GAM41608.1 - 0.0056 16.2 0.7 1.9 8.2 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger HypA PF01155.19 GAM41608.1 - 0.018 15.1 0.3 0.022 14.8 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TFIIS_C PF01096.18 GAM41608.1 - 0.018 14.9 0.4 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DZR PF12773.7 GAM41608.1 - 0.029 14.4 0.5 0.042 13.9 0.5 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 GAM41608.1 - 0.03 14.0 0.3 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_ribbon_recom PF13408.6 GAM41608.1 - 0.045 14.3 0.7 2.5 8.7 0.1 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain ADK_lid PF05191.14 GAM41608.1 - 0.049 13.6 1.1 0.049 13.6 1.1 1.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid Nudix_N_2 PF14803.6 GAM41608.1 - 0.052 13.5 1.4 8.5 6.4 0.1 2.6 3 0 0 3 3 3 0 Nudix N-terminal TackOD1 PF18551.1 GAM41608.1 - 0.055 13.1 0.2 0.067 12.9 0.2 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-C2H2_11 PF16622.5 GAM41608.1 - 0.11 12.3 1.6 1.2 9.0 0.3 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 GAM41608.1 - 0.74 10.0 4.6 6.7 6.9 0.5 2.1 1 1 1 2 2 2 0 Zinc ribbon domain Ribosomal_L44 PF00935.19 GAM41608.1 - 0.96 10.0 3.7 1.9 9.0 0.8 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 Fe_hyd_lg_C PF02906.14 GAM41609.1 - 5.7e-53 180.1 0.0 1.7e-52 178.5 0.0 1.9 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fapy_DNA_glyco PF01149.24 GAM41609.1 - 3.3e-35 121.2 0.0 7.2e-35 120.1 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 GAM41609.1 - 4.3e-22 77.9 0.1 3.4e-21 75.0 0.0 2.5 3 0 0 3 3 3 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 GAM41609.1 - 0.0013 17.5 0.0 0.0035 16.2 0.0 1.7 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.22 GAM41609.1 - 0.012 16.0 1.7 0.087 13.2 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein S13/S18 NARP1 PF12569.8 GAM41610.1 - 1.8e-222 739.8 16.3 2.5e-219 729.5 12.5 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 GAM41610.1 - 3.5e-21 75.5 25.7 0.0027 18.2 0.1 7.8 7 1 1 8 8 7 7 Tetratricopeptide repeat TPR_14 PF13428.6 GAM41610.1 - 6.8e-18 63.8 18.6 0.12 13.2 0.2 11.1 7 4 5 12 12 11 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM41610.1 - 7.7e-17 60.0 31.9 0.0012 18.8 0.2 11.2 12 0 0 12 12 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAM41610.1 - 1.3e-14 54.6 16.5 0.062 14.0 0.9 8.6 6 1 2 9 9 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM41610.1 - 5.3e-14 52.2 5.1 1.2e-05 25.5 0.7 5.0 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 GAM41610.1 - 4.7e-11 42.2 3.7 0.0001 21.9 0.1 5.7 6 0 0 6 6 6 2 TPR repeat TPR_9 PF13371.6 GAM41610.1 - 3.2e-10 40.0 11.1 0.0022 18.1 1.4 6.0 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM41610.1 - 1.6e-07 31.0 22.4 0.0008 19.4 0.0 8.4 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM41610.1 - 2.7e-07 30.5 3.3 0.61 10.6 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM41610.1 - 1.2e-05 24.9 31.2 3.9e-05 23.3 0.5 9.7 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAM41610.1 - 6.4e-05 22.3 7.6 0.024 13.8 0.3 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM41610.1 - 0.0013 19.0 27.3 1.1 9.5 0.3 8.6 7 2 1 9 9 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAM41610.1 - 0.02 15.5 4.5 9.9 7.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 GAM41610.1 - 0.02 14.9 0.9 2.2 8.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM41610.1 - 0.044 14.4 18.5 2.3 9.0 0.2 7.8 10 0 0 10 10 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM41610.1 - 0.079 13.1 6.7 0.95 9.6 0.1 4.4 4 1 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 GAM41610.1 - 0.56 10.6 8.2 0.12 12.9 1.1 3.6 3 2 0 3 3 3 0 Bacterial transcriptional activator domain DUF2229 PF09989.9 GAM41610.1 - 1.8 8.2 6.3 0.52 9.9 0.7 2.7 3 0 0 3 3 3 0 CoA enzyme activase uncharacterised domain (DUF2229) Phage_Nu1 PF07471.12 GAM41610.1 - 6.3 6.5 7.5 3.3 7.4 2.0 2.5 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 CwfJ_C_2 PF04676.14 GAM41611.1 - 4.7e-29 101.2 0.1 4.7e-29 101.2 0.1 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 GAM41611.1 - 3e-28 98.2 0.0 8.5e-28 96.7 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 FumaraseC_C PF10415.9 GAM41611.1 - 0.23 11.9 0.6 12 6.4 0.1 2.7 2 0 0 2 2 2 0 Fumarase C C-terminus DUF3010 PF11215.8 GAM41611.1 - 0.27 11.5 0.7 1.2e+02 2.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3010) 2-Hacid_dh_C PF02826.19 GAM41612.1 - 2e-58 196.7 0.0 2.7e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAM41612.1 - 1.1e-15 57.5 0.0 1.5e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAM41612.1 - 0.00012 22.3 0.1 0.00024 21.3 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 GAM41612.1 - 0.0085 15.7 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 GAM41612.1 - 0.043 13.7 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 Rossmann-like domain AdoHcyase_NAD PF00670.21 GAM41612.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CAP_GLY PF01302.25 GAM41614.1 - 1.6e-19 69.7 0.2 4e-19 68.4 0.2 1.7 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 GAM41614.1 - 3.2e-12 46.4 12.3 0.0007 19.9 0.0 5.9 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM41614.1 - 1.5e-07 31.0 16.7 0.032 14.0 0.0 4.8 3 1 1 5 5 5 4 Leucine rich repeat zf-U1 PF06220.12 GAM41614.1 - 1.2e-06 28.2 0.7 2e-06 27.4 0.7 1.4 1 0 0 1 1 1 1 U1 zinc finger LRR_9 PF14580.6 GAM41614.1 - 3.8e-06 26.5 2.0 0.66 9.5 0.8 3.7 1 1 3 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 GAM41614.1 - 9e-06 25.4 10.6 0.062 13.4 0.1 5.7 6 0 0 6 6 6 3 Leucine Rich repeat DUF1619 PF07773.11 GAM41614.1 - 0.0034 17.4 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1619) SF3A2 PF16835.5 GAM41615.1 - 2.9e-36 123.7 0.0 4.4e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 GAM41615.1 - 1.8e-05 24.9 1.7 2e-05 24.8 0.5 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 GAM41615.1 - 0.047 13.3 1.5 0.11 12.1 1.5 1.7 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.25 GAM41616.1 - 1.1e-54 185.6 0.0 1.7e-53 181.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM41616.1 - 7.9e-25 87.6 0.5 1.8e-19 70.0 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 GAM41616.1 - 4.7e-06 25.8 0.1 6.7e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAM41616.1 - 6.7e-05 22.9 3.8 0.021 14.8 0.1 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 GAM41616.1 - 0.00026 20.4 0.0 0.00066 19.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAM41616.1 - 0.0016 17.8 0.4 0.0037 16.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 GAM41616.1 - 0.0071 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 GAM41616.1 - 0.031 13.1 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 GAM41616.1 - 0.039 13.6 0.2 8 6.0 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 NFACT-C PF11923.8 GAM41616.1 - 0.19 11.6 0.2 0.4 10.6 0.2 1.5 1 0 0 1 1 1 0 NFACT protein C-terminal domain Tim54 PF11711.8 GAM41617.1 - 5.5e-150 499.3 0.4 6.7e-150 499.0 0.4 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 ATP_bind_1 PF03029.17 GAM41618.1 - 3.8e-63 213.5 0.0 4.9e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 GAM41618.1 - 0.00062 19.4 0.0 0.0018 17.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 GAM41618.1 - 0.024 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 GAM41618.1 - 0.027 14.0 0.0 0.068 12.7 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 GAM41618.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Hexapep_2 PF14602.6 GAM41619.1 - 9.2e-13 47.7 4.9 7.5e-10 38.4 2.0 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 GAM41619.1 - 2.1e-12 46.2 11.2 6.6e-10 38.3 2.5 3.1 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 GAM41619.1 - 8.7e-11 41.9 0.1 1.4e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase DUF525 PF04379.14 GAM41619.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 ApaG domain GST_N_3 PF13417.6 GAM41620.1 - 3e-20 72.4 0.0 6.2e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM41620.1 - 8.7e-17 61.2 0.2 5.2e-16 58.7 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAM41620.1 - 6e-09 36.1 0.0 1.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM41620.1 - 1.8e-05 24.6 0.0 4.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GAM41620.1 - 0.00024 21.7 0.0 0.00049 20.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GAM41620.1 - 0.0036 17.5 0.0 0.009 16.2 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 GAM41620.1 - 0.0062 16.7 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SUZ PF12752.7 GAM41621.1 - 0.00014 22.5 10.2 0.00014 22.5 10.2 4.9 3 2 0 3 3 3 1 SUZ domain eIF3_subunit PF08597.10 GAM41621.1 - 1 9.2 9.7 4.5 7.1 4.1 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Hydrolase_6 PF13344.6 GAM41624.1 - 9.4e-21 73.8 0.0 1.7e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM41624.1 - 7.6e-20 70.8 0.0 2e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 GAM41624.1 - 0.0027 17.8 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM41624.1 - 0.028 14.7 0.0 7.4 6.8 0.0 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase 5-nucleotidase PF06189.12 GAM41624.1 - 0.041 12.8 0.2 0.065 12.2 0.2 1.3 1 0 0 1 1 1 0 5'-nucleotidase Aldo_ket_red PF00248.21 GAM41625.1 - 2.7e-49 167.9 0.0 7.1e-49 166.6 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_127 PF07944.12 GAM41626.1 - 2.3e-121 405.9 0.1 2.7e-121 405.6 0.1 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 ADH_zinc_N PF00107.26 GAM41627.1 - 1e-26 93.5 0.5 1.5e-26 92.9 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM41627.1 - 1.9e-17 64.5 0.0 5.7e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM41627.1 - 8.9e-07 28.8 0.0 2.2e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Peripla_BP_6 PF13458.6 GAM41627.1 - 0.041 13.5 2.4 0.14 11.8 0.5 2.0 1 1 1 2 2 2 0 Periplasmic binding protein DUF1751 PF08551.10 GAM41628.1 - 0.0017 18.9 0.2 0.0037 17.8 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) MFS_1 PF07690.16 GAM41629.1 - 2e-38 132.2 22.8 4.4e-37 127.8 22.8 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM41629.1 - 6.3e-08 31.9 13.6 6.3e-08 31.9 13.6 3.1 3 1 0 3 3 3 2 Sugar (and other) transporter BSD PF03909.17 GAM41630.1 - 1.1e-30 105.4 11.2 1.1e-15 57.4 0.8 3.2 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 GAM41630.1 - 4.9e-27 94.1 0.1 1.6e-26 92.5 0.1 1.9 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain CHIP_TPR_N PF18391.1 GAM41630.1 - 0.23 12.3 0.1 0.23 12.3 0.1 3.6 4 1 1 5 5 5 0 CHIP N-terminal tetratricopeptide repeat domain ING PF12998.7 GAM41631.1 - 1e-11 45.3 0.1 4.6e-11 43.2 0.1 2.1 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding F-box-like PF12937.7 GAM41631.1 - 7.9e-06 25.7 0.2 2e-05 24.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like PHD PF00628.29 GAM41631.1 - 0.0063 16.4 1.1 0.015 15.2 1.1 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 GAM41631.1 - 0.017 15.4 0.3 0.037 14.3 0.3 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF4378 PF14309.6 GAM41631.1 - 0.069 13.5 0.2 0.75 10.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) zf-HC5HC2H_2 PF13832.6 GAM41631.1 - 0.1 12.8 0.3 0.24 11.6 0.3 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain LRR_6 PF13516.6 GAM41631.1 - 4.2 7.7 6.4 34 4.9 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat Transket_pyr PF02779.24 GAM41632.1 - 2.1e-64 216.5 0.0 3.8e-64 215.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 GAM41632.1 - 1.9e-59 201.0 0.0 2.9e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 GAM41632.1 - 2.3e-57 193.0 0.0 3.9e-57 192.2 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 GAM41632.1 - 1.6e-19 69.2 0.9 1.6e-19 69.2 0.9 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus DUF2680 PF10925.8 GAM41632.1 - 0.08 13.0 0.4 0.31 11.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) Nucleo_P87 PF07267.11 GAM41633.1 - 3.5 6.4 5.4 6 5.6 5.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PIN_9 PF18477.1 GAM41634.1 - 0.2 12.0 0.9 2.3 8.6 0.3 2.5 2 0 0 2 2 2 0 PIN like domain DUF883 PF05957.13 GAM41634.1 - 3.5 8.3 7.7 1.3 9.7 2.4 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PNP_UDP_1 PF01048.20 GAM41635.1 - 3.9e-15 55.8 0.2 1.1e-14 54.3 0.2 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 GAM41636.1 - 4.8e-35 120.0 7.9 4.2e-10 40.1 0.3 6.0 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM41636.1 - 2.5e-28 98.1 3.8 3.1e-07 30.8 0.0 7.6 3 2 6 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM41636.1 - 7.7e-28 93.5 3.4 5.5e-05 23.2 0.0 10.0 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 GAM41636.1 - 3.6e-23 81.3 9.5 2.7e-07 30.8 0.0 7.5 5 1 2 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 GAM41636.1 - 1e-21 76.4 10.9 8.7e-05 22.8 0.0 9.6 10 0 0 10 10 9 3 Ankyrin repeat Sld5 PF05916.11 GAM41636.1 - 1.7e-21 76.7 0.1 7.8e-21 74.6 0.0 2.2 2 0 0 2 2 1 1 GINS complex protein NACHT PF05729.12 GAM41636.1 - 3.7e-07 30.2 1.3 4.6e-06 26.7 0.6 2.7 2 1 0 2 2 2 1 NACHT domain KAP_NTPase PF07693.14 GAM41636.1 - 7.3e-05 22.2 2.0 0.17 11.1 0.6 2.2 1 1 0 2 2 2 2 KAP family P-loop domain DUF1843 PF08898.10 GAM41636.1 - 0.00016 22.1 5.3 0.011 16.2 0.1 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF1843) AAA_22 PF13401.6 GAM41636.1 - 0.0004 20.7 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM41636.1 - 0.00064 20.1 0.0 0.002 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 GAM41636.1 - 0.0017 18.1 0.0 0.0063 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAM41636.1 - 0.016 15.6 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase YajC PF02699.15 GAM41636.1 - 0.02 14.8 0.3 1.2 9.0 0.0 3.4 2 1 2 4 4 3 0 Preprotein translocase subunit AAA_5 PF07728.14 GAM41636.1 - 0.02 14.9 0.0 0.49 10.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 GAM41636.1 - 0.034 14.6 0.0 0.11 13.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 GAM41636.1 - 0.047 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ATPase_2 PF01637.18 GAM41636.1 - 0.077 12.9 0.0 0.19 11.6 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 GAM41636.1 - 0.096 13.2 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAM41636.1 - 0.097 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 GAM41636.1 - 0.11 13.0 0.0 0.34 11.4 0.0 1.9 1 0 0 1 1 1 0 ABC transporter adh_short PF00106.25 GAM41638.1 - 8.8e-09 35.1 0.0 0.0007 19.1 0.0 3.2 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 GAM41638.1 - 0.0095 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 GAM41638.1 - 0.2 11.2 0.0 19 4.7 0.0 2.2 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase zf-C2H2 PF00096.26 GAM41639.1 - 1.8e-17 62.7 33.5 5.7e-05 23.3 3.3 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM41639.1 - 8.4e-16 57.6 24.9 3.9e-06 27.0 1.0 4.9 4 1 1 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAM41639.1 - 1.9e-07 31.3 30.3 0.064 14.1 2.7 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 GAM41639.1 - 0.016 15.5 10.8 0.056 13.7 5.5 3.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 GAM41639.1 - 0.022 15.4 12.0 0.92 10.2 0.2 4.3 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 GAM41639.1 - 0.68 10.3 7.5 36 4.8 0.0 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-tcix PF14952.6 GAM41639.1 - 0.73 9.5 4.2 4.2 7.1 0.2 2.9 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding zf-met PF12874.7 GAM41639.1 - 2.3 8.7 13.8 13 6.3 0.5 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-CGNR PF11706.8 GAM41639.1 - 5.9 6.8 15.0 0.79 9.6 0.5 4.1 4 0 0 4 4 4 0 CGNR zinc finger TFIIA PF03153.13 GAM41639.1 - 8.4 6.3 11.3 10 6.0 11.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SHR-BD PF06650.12 GAM41640.1 - 2.3e-98 328.9 0.0 4.8e-97 324.6 0.0 2.8 2 1 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 GAM41640.1 - 1.6e-80 270.3 0.0 5.1e-79 265.4 0.0 3.5 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 GAM41640.1 - 4.1e-73 245.0 4.4 1.5e-69 233.4 0.1 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 GAM41640.1 - 1e-44 152.7 9.4 9.7e-40 136.5 0.0 5.9 4 1 0 5 5 5 2 Repeating coiled region of VPS13 Chorein_N PF12624.7 GAM41640.1 - 3.9e-41 139.8 0.0 1.3e-40 138.2 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 GAM41640.1 - 1.8e-06 28.2 0.1 1.3e-05 25.5 0.0 2.5 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain DUF896 PF05979.12 GAM41640.1 - 0.038 13.9 6.4 0.62 10.0 0.3 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) DUF3429 PF11911.8 GAM41641.1 - 1.5e-43 148.6 10.5 2.2e-43 148.0 10.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FGGY_C PF02782.16 GAM41642.1 - 2.6e-74 249.3 1.2 4.4e-74 248.5 1.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GAM41642.1 - 3.6e-62 210.1 0.0 4.8e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF3140 PF11338.8 GAM41642.1 - 0.015 15.7 0.4 0.037 14.4 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) BcrAD_BadFG PF01869.20 GAM41642.1 - 0.022 14.2 0.7 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M41 PF01434.18 GAM41643.1 - 1.9e-57 194.2 0.4 3.7e-57 193.3 0.4 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAM41643.1 - 1.3e-42 145.4 0.0 3.3e-42 144.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM41643.1 - 2.5e-11 43.2 0.0 6.8e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAM41643.1 - 1e-05 25.5 0.0 3.5e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM41643.1 - 4.3e-05 24.0 0.4 0.00029 21.3 0.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 GAM41643.1 - 4.9e-05 22.7 0.1 0.00012 21.4 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 GAM41643.1 - 0.00028 21.2 2.3 0.028 14.7 0.2 3.1 3 1 0 3 3 1 1 AAA domain RuvB_N PF05496.12 GAM41643.1 - 0.00033 20.5 0.0 0.00095 18.9 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAM41643.1 - 0.0038 17.4 0.0 0.013 15.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 GAM41643.1 - 0.0093 15.2 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 GAM41643.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 GAM41643.1 - 0.021 15.0 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 GAM41643.1 - 0.027 13.9 0.3 0.052 12.9 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAM41643.1 - 0.035 14.7 0.0 0.093 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAM41643.1 - 0.036 13.6 1.9 0.61 9.6 0.3 2.4 1 1 1 2 2 2 0 AAA domain ATPase PF06745.13 GAM41643.1 - 0.055 12.8 0.1 1.5 8.1 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 GAM41643.1 - 0.07 13.4 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 GAM41643.1 - 0.11 12.9 0.3 0.29 11.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 GAM41643.1 - 0.18 11.3 0.1 0.48 9.9 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 GAM41643.1 - 0.28 11.1 2.8 1.8 8.4 0.1 2.7 3 0 0 3 3 3 0 NACHT domain MFS_1 PF07690.16 GAM41644.1 - 2e-32 112.5 72.4 7.4e-25 87.6 33.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM41644.1 - 1.2e-12 47.4 28.1 1.4e-06 27.5 7.0 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter NTP_transferase PF00483.23 GAM41645.1 - 6.5e-53 179.9 0.0 1.3e-52 178.9 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 GAM41645.1 - 2.3e-14 52.4 6.7 5.7e-11 41.7 1.6 3.0 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 GAM41645.1 - 1.3e-09 38.6 0.0 1.9e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 GAM41645.1 - 1.6e-06 27.7 6.9 2.1e-06 27.4 0.9 3.0 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 GAM41645.1 - 0.034 12.3 0.1 0.053 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) SRP54 PF00448.22 GAM41645.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IspD PF01128.19 GAM41645.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Sod_Fe_C PF02777.18 GAM41646.1 - 5.9e-36 122.7 1.2 1.1e-35 121.9 0.4 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GAM41646.1 - 6e-24 84.3 1.9 1.1e-23 83.5 1.9 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GCFC PF07842.12 GAM41647.1 - 1.3e-84 284.1 8.5 1.3e-84 284.1 8.5 1.5 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 GAM41647.1 - 2.7e-15 56.0 2.5 2.7e-15 56.0 2.5 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 GAM41647.1 - 1.9e-06 27.8 1.9 1.9e-06 27.8 1.9 2.2 2 0 0 2 2 2 1 G-patch domain Suc_Fer-like PF06999.12 GAM41648.1 - 7.6e-69 231.5 0.0 9.1e-69 231.2 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF2849 PF11011.8 GAM41648.1 - 0.14 12.8 0.9 0.34 11.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) NICE-3 PF07406.11 GAM41649.1 - 0.068 13.2 0.0 4.2 7.3 0.0 2.2 2 0 0 2 2 2 0 NICE-3 protein Aminotran_1_2 PF00155.21 GAM41650.1 - 1.3e-33 116.6 0.0 1.5e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PH_10 PF15411.6 GAM41651.1 - 1e-40 138.8 0.0 2.4e-40 137.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 GAM41651.1 - 1.2e-35 121.6 0.0 2.4e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 GAM41651.1 - 3.2e-23 82.9 1.0 5.3e-23 82.2 1.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 GAM41651.1 - 1.1e-08 34.9 0.1 2.3e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 GAM41651.1 - 0.085 13.4 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 PH domain WD40 PF00400.32 GAM41652.1 - 2.1e-31 107.5 8.1 0.00012 22.7 0.1 8.3 9 0 0 9 9 9 5 WD domain, G-beta repeat F-box-like PF12937.7 GAM41652.1 - 5.5e-12 45.4 0.4 1.4e-11 44.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM41652.1 - 2.3e-08 33.7 0.0 5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 GAM41652.1 - 0.00024 21.3 0.3 1.1 9.6 0.0 3.6 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM41652.1 - 0.0056 16.1 0.1 1.4 8.2 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain PALB2_WD40 PF16756.5 GAM41652.1 - 0.16 10.8 0.0 0.77 8.6 0.0 1.9 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 GAM41652.1 - 0.38 9.3 1.6 6.2 5.3 0.0 2.9 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Uds1 PF15456.6 GAM41653.1 - 1e-43 148.6 1.5 1e-43 148.6 1.5 6.9 3 1 4 7 7 7 1 Up-regulated During Septation APG6_N PF17675.1 GAM41653.1 - 0.009 16.5 8.4 0.009 16.5 8.4 7.9 3 2 4 7 7 7 2 Apg6 coiled-coil region CLZ PF16526.5 GAM41653.1 - 1.1 9.7 71.9 0.07 13.5 2.7 11.9 8 4 6 14 14 14 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Dynamitin PF04912.14 GAM41653.1 - 7.2 5.8 69.3 0.042 13.2 11.1 6.6 3 1 4 7 7 7 0 Dynamitin HsbA PF12296.8 GAM41653.1 - 8.7 6.8 10.3 2.9 8.3 3.7 3.4 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Lactamase_B PF00753.27 GAM41655.1 - 2.5e-12 47.2 0.1 6.6e-12 45.9 0.1 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM41655.1 - 6e-05 22.6 0.1 0.00015 21.4 0.1 1.8 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAM41655.1 - 0.0014 18.6 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_hydro_12 PF01670.16 GAM41656.1 - 1.2e-76 257.4 15.9 1.4e-76 257.2 15.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 MFS_1 PF07690.16 GAM41657.1 - 5.7e-29 101.1 31.6 5.7e-29 101.1 31.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 GAM41657.1 - 6.6e-09 34.8 1.0 6.6e-09 34.8 1.0 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 GAM41657.1 - 2.1e-05 23.6 1.5 2.1e-05 23.6 1.5 3.2 1 1 3 4 4 4 1 MFS_1 like family UCR_hinge PF02320.16 GAM41658.1 - 4.6e-27 94.0 6.0 4.6e-27 94.0 6.0 2.0 2 1 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein Mitofilin PF09731.9 GAM41658.1 - 0.0091 14.9 15.5 0.0099 14.8 15.5 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RR_TM4-6 PF06459.12 GAM41658.1 - 0.0096 15.8 12.4 0.01 15.7 12.4 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Mpp10 PF04006.12 GAM41658.1 - 0.025 13.0 18.9 0.027 12.9 18.9 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 GAM41658.1 - 0.068 12.5 20.1 0.077 12.3 20.1 1.0 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 GAM41658.1 - 0.27 10.6 23.8 0.41 10.0 23.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SAPS PF04499.15 GAM41658.1 - 0.61 8.8 7.5 0.65 8.7 7.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4045 PF13254.6 GAM41658.1 - 0.63 9.6 13.1 0.72 9.4 13.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CCDC53 PF10152.9 GAM41658.1 - 0.64 10.4 10.9 0.97 9.8 10.9 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SpoIIP PF07454.11 GAM41658.1 - 0.67 9.4 8.0 0.84 9.0 8.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Nop14 PF04147.12 GAM41658.1 - 0.96 7.6 23.3 1.1 7.4 23.3 1.0 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 GAM41658.1 - 1.6 8.7 37.6 2.1 8.3 37.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SDA1 PF05285.12 GAM41658.1 - 1.9 7.8 22.9 2.1 7.7 22.9 1.1 1 0 0 1 1 1 0 SDA1 PA26 PF04636.13 GAM41658.1 - 2.1 7.2 6.1 2.4 7.0 6.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Raftlin PF15250.6 GAM41658.1 - 2.2 7.0 9.3 2.3 6.9 9.3 1.1 1 0 0 1 1 1 0 Raftlin MDM10 PF12519.8 GAM41658.1 - 2.3 7.0 5.1 2.6 6.8 5.1 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SLC12 PF03522.15 GAM41658.1 - 2.3 7.1 4.4 2.5 7.0 4.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Spore_coat_CotO PF14153.6 GAM41658.1 - 3.2 7.7 23.5 4 7.3 23.5 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Lin-8 PF03353.15 GAM41658.1 - 3.6 7.0 13.4 4.4 6.8 13.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 GAM41658.1 - 4.2 5.5 16.3 4.6 5.4 16.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 GAM41658.1 - 4.3 6.6 25.4 4.8 6.5 25.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF913 PF06025.12 GAM41658.1 - 5.4 5.9 8.6 6.3 5.7 8.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 GAM41658.1 - 6 5.5 12.6 6.8 5.4 12.6 1.1 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 GAM41658.1 - 6 5.5 17.5 7.1 5.3 17.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 GAM41658.1 - 6.1 6.8 5.5 7.1 6.6 5.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 GAM41658.1 - 6.3 4.8 9.6 6.6 4.7 9.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDRGK PF09756.9 GAM41658.1 - 6.7 6.3 19.7 8.2 6.0 19.7 1.2 1 0 0 1 1 1 0 DDRGK domain Zip PF02535.22 GAM41658.1 - 7.8 5.6 7.4 8.1 5.6 7.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Vps36_ESCRT-II PF11605.8 GAM41659.1 - 5.3e-05 23.3 0.0 0.0021 18.2 0.0 2.2 1 1 1 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 GAM41659.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.6 1 1 0 1 1 1 0 GRAM domain Acyltransferase PF01553.21 GAM41660.1 - 2.1e-09 37.1 0.0 0.00072 19.2 0.0 2.2 2 0 0 2 2 2 2 Acyltransferase PRA-PH PF01503.17 GAM41660.1 - 0.013 15.9 0.1 0.058 13.8 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Prenyltransf PF01255.19 GAM41661.1 - 4.6e-79 265.1 0.0 6.7e-79 264.5 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Ppx-GppA PF02541.16 GAM41662.1 - 4e-41 141.3 0.0 1.5e-40 139.5 0.0 1.7 1 1 0 1 1 1 1 Ppx/GppA phosphatase family MFS_1 PF07690.16 GAM41662.1 - 3.2e-25 88.8 23.6 6.6e-25 87.8 23.6 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM41662.1 - 1.3e-06 27.6 13.2 2.1e-06 26.9 12.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter GDA1_CD39 PF01150.17 GAM41662.1 - 0.27 9.9 0.0 0.4 9.3 0.0 1.2 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family TPR_2 PF07719.17 GAM41663.1 - 1e-06 28.4 13.5 0.0027 17.7 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAM41663.1 - 2.9e-06 26.8 6.1 0.033 14.0 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM41663.1 - 1.3e-05 24.8 8.9 0.77 9.5 0.1 5.6 7 0 0 7 7 7 2 TPR repeat TPR_19 PF14559.6 GAM41663.1 - 0.00014 22.2 9.4 0.088 13.3 0.5 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM41663.1 - 0.0082 16.9 11.1 3.1 8.9 0.1 6.2 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM41663.1 - 0.013 15.8 1.5 1.1e+02 3.6 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAM41663.1 - 0.071 13.8 6.4 13 6.5 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM41663.1 - 0.66 10.3 3.1 13 6.3 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM41663.1 - 0.82 10.0 8.3 3.6 7.9 2.1 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 GAM41664.1 - 2e-46 158.8 0.0 2.5e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Death_2 PF14786.6 GAM41664.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Tube Death domain TPR_2 PF07719.17 GAM41665.1 - 8.1e-10 38.1 6.1 0.0055 16.7 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAM41665.1 - 5.6e-08 32.3 3.2 0.073 12.9 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM41665.1 - 0.00019 21.1 0.5 5 6.9 0.0 4.4 4 0 0 4 4 4 1 TPR repeat TPR_12 PF13424.6 GAM41665.1 - 0.0012 19.1 5.5 0.23 11.8 1.3 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAM41665.1 - 0.0026 18.2 3.6 0.32 11.7 2.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM41665.1 - 0.0032 17.6 0.2 18 5.9 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM41665.1 - 0.0034 16.8 0.8 0.03 13.7 0.1 2.5 3 0 0 3 3 3 1 MalT-like TPR region TPR_14 PF13428.6 GAM41665.1 - 0.0075 17.0 8.5 7.6 7.6 0.7 4.7 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM41665.1 - 0.011 16.4 5.1 25 5.6 2.9 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM41665.1 - 0.014 15.9 0.5 0.51 10.9 0.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM41665.1 - 0.017 15.1 2.6 45 4.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM41665.1 - 0.019 15.2 1.7 0.26 11.5 0.1 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Bystin PF05291.11 GAM41665.1 - 0.1 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Bystin TPR_10 PF13374.6 GAM41665.1 - 0.69 9.9 4.5 29 4.7 1.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Sacchrp_dh_C PF16653.5 GAM41666.1 - 9.8e-94 314.3 0.0 3.8e-93 312.4 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 GAM41666.1 - 3e-25 89.0 1.2 4.6e-25 88.4 1.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAM41666.1 - 4e-07 30.2 0.3 8.1e-07 29.2 0.3 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 GAM41666.1 - 3.9e-06 26.9 1.3 4.3e-06 26.8 0.4 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_7 PF13241.6 GAM41666.1 - 2.2e-05 24.8 0.3 4.4e-05 23.9 0.3 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 GAM41666.1 - 7.1e-05 22.2 0.8 0.00011 21.6 0.8 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 GAM41666.1 - 0.00068 19.2 0.1 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.16 GAM41666.1 - 0.0027 18.3 1.4 0.0044 17.7 1.4 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NmrA PF05368.13 GAM41666.1 - 0.0028 17.2 0.6 0.0043 16.6 0.6 1.2 1 0 0 1 1 1 1 NmrA-like family GFO_IDH_MocA PF01408.22 GAM41666.1 - 0.0085 16.9 0.1 0.014 16.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 GAM41666.1 - 0.0085 16.5 0.3 0.016 15.6 0.3 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain IlvN PF07991.12 GAM41666.1 - 0.011 15.3 0.9 0.027 14.0 0.4 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 GAM41666.1 - 0.021 15.1 1.1 0.037 14.3 1.1 1.4 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 GAM41666.1 - 0.044 13.1 0.1 0.1 12.0 0.1 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAM41666.1 - 0.1 11.6 0.1 0.19 10.7 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aha1_N PF09229.11 GAM41667.1 - 2.6e-40 137.8 3.1 4.1e-40 137.2 2.1 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 GAM41667.1 - 1.4e-19 70.5 0.8 2.6e-19 69.7 0.8 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein MAGE_N PF12440.8 GAM41667.1 - 3 8.6 7.7 4.7 8.0 1.3 2.5 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal FBPase PF00316.20 GAM41669.1 - 1.1e-67 227.2 0.0 1.5e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain V_ATPase_I PF01496.19 GAM41670.1 - 0 1068.9 0.0 0 1068.7 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DASH_Dam1 PF08653.10 GAM41670.1 - 0.019 14.8 0.3 11 5.9 0.0 4.0 4 0 0 4 4 4 0 DASH complex subunit Dam1 CheZ PF04344.13 GAM41670.1 - 0.041 13.8 2.3 0.25 11.2 0.1 2.3 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF1515 PF07439.11 GAM41670.1 - 0.081 13.0 0.5 0.19 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF3552 PF12072.8 GAM41670.1 - 0.14 11.5 2.2 5.7 6.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Filament PF00038.21 GAM41670.1 - 0.22 11.1 2.7 7.5 6.0 0.4 2.3 2 0 0 2 2 2 0 Intermediate filament protein RraA-like PF03737.15 GAM41671.1 - 1.4e-25 90.2 0.2 1.8e-25 89.9 0.2 1.2 1 0 0 1 1 1 1 Aldolase/RraA MWFE PF15879.5 GAM41671.1 - 4.6e-17 61.9 0.0 9.3e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit NTP_transf_3 PF12804.7 GAM41671.1 - 0.016 15.6 0.1 0.024 15.0 0.1 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain MOZ_SAS PF01853.18 GAM41672.1 - 8.1e-75 250.4 0.0 1.3e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GAM41672.1 - 4.8e-21 74.1 3.3 1.1e-20 72.9 3.3 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 GAM41672.1 - 3.5e-12 46.2 8.9 1.6e-11 44.1 8.3 2.4 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 GAM41672.1 - 0.0046 16.8 10.3 0.0046 16.8 10.3 2.2 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 GAM41672.1 - 3.8 7.5 6.6 10 6.1 6.6 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Velvet PF11754.8 GAM41673.1 - 1.1e-42 146.7 5.2 3.8e-32 112.2 0.3 2.5 1 1 1 2 2 2 2 Velvet factor Fungal_trans PF04082.18 GAM41673.1 - 9.2e-14 51.1 0.1 1.6e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cep3 PF16846.5 GAM41673.1 - 0.026 13.0 0.7 0.039 12.4 0.7 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Zn_clus PF00172.18 GAM41673.1 - 0.051 13.7 0.4 0.12 12.6 0.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NOA36 PF06524.12 GAM41673.1 - 5.7 6.2 8.3 1.1 8.5 3.8 1.9 2 0 0 2 2 2 0 NOA36 protein zf-PHD-like PF15446.6 GAM41674.1 - 0.2 11.3 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Pro_CA PF00484.19 GAM41675.1 - 2.9e-42 144.6 0.4 5.2e-42 143.8 0.0 1.5 2 0 0 2 2 2 1 Carbonic anhydrase Mannosyl_trans2 PF04188.13 GAM41677.1 - 7.7e-54 183.7 12.0 1.5e-53 182.7 12.0 1.4 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) BLM10_mid PF16507.5 GAM41678.1 - 3.3e-213 709.1 0.0 5.6e-213 708.3 0.0 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 GAM41678.1 - 1.9e-30 104.6 0.0 3.3e-29 100.6 0.0 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 GAM41678.1 - 1e-20 73.8 0.1 1.8e-19 69.8 0.0 2.7 3 0 0 3 3 3 1 Proteasome-substrate-size regulator, N-terminal CLASP_N PF12348.8 GAM41678.1 - 0.004 16.8 0.7 2.1 7.9 0.1 3.6 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 GAM41678.1 - 0.01 16.0 0.1 7.7 7.1 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 GAM41678.1 - 0.029 14.9 0.0 27 5.4 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat Thiolase_N PF00108.23 GAM41679.1 - 1.1e-75 254.4 0.9 1.9e-75 253.6 0.9 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAM41679.1 - 6.4e-43 145.3 0.2 1.4e-42 144.2 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAM41679.1 - 0.0038 16.9 0.4 0.026 14.1 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Cadherin_tail PF15974.5 GAM41679.1 - 0.089 13.1 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region ACP_syn_III PF08545.10 GAM41679.1 - 0.14 12.0 1.2 15 5.5 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HET PF06985.11 GAM41680.1 - 6.4e-12 46.0 7.9 2.8e-11 43.9 0.1 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 GAM41681.1 - 6e-14 51.7 43.1 6e-14 51.7 43.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM41681.1 - 7.5e-07 28.4 12.5 7.5e-07 28.4 12.5 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter FAD_binding_3 PF01494.19 GAM41683.1 - 1.4e-14 54.2 6.9 5.8e-07 29.1 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAM41683.1 - 8.2e-06 25.3 0.5 0.00051 19.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM41683.1 - 7.7e-05 22.8 2.4 0.00018 21.7 2.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAM41683.1 - 0.0019 18.2 3.8 0.28 11.1 2.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding SE PF08491.10 GAM41683.1 - 0.0051 15.9 0.0 0.13 11.3 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.24 GAM41683.1 - 0.0082 15.5 1.0 0.81 8.9 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 GAM41683.1 - 0.0095 15.6 6.1 0.026 14.1 4.7 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 GAM41683.1 - 0.062 12.4 0.4 0.12 11.5 0.3 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 GAM41683.1 - 0.07 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 GAM41683.1 - 0.078 12.0 4.3 0.16 11.0 4.3 1.7 1 1 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 GAM41683.1 - 0.096 11.4 0.7 0.15 10.7 0.7 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 GAM41683.1 - 0.22 12.1 3.3 0.29 11.7 1.7 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Drf_GBD PF06371.13 GAM41684.1 - 8.9e-17 61.3 3.7 1.9e-15 57.0 3.7 2.4 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Nramp PF01566.18 GAM41685.1 - 6.5e-94 314.8 15.5 6.5e-94 314.8 15.5 1.6 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein DUF1129 PF06570.11 GAM41685.1 - 2.7 7.4 5.7 0.96 8.9 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2755 PF10954.8 GAM41685.1 - 9.2 6.3 7.8 27 4.7 2.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2755) Snf7 PF03357.21 GAM41686.1 - 1.1e-43 148.9 13.1 1.3e-43 148.6 13.1 1.0 1 0 0 1 1 1 1 Snf7 Zwint PF15556.6 GAM41686.1 - 0.0017 17.9 4.7 0.0023 17.5 4.7 1.3 1 0 0 1 1 1 1 ZW10 interactor DUF4201 PF13870.6 GAM41686.1 - 0.0018 18.0 7.2 0.0018 18.0 7.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) NPV_P10 PF05531.12 GAM41686.1 - 0.0051 17.2 5.7 0.6 10.6 1.0 2.8 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 GAM41686.1 - 0.011 16.0 4.2 2.2 8.7 0.0 3.3 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Alpha-2-MRAP_C PF06401.11 GAM41686.1 - 0.015 15.3 4.1 0.024 14.6 3.3 1.7 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain bZIP_1 PF00170.21 GAM41686.1 - 0.035 14.2 4.8 4.5 7.4 1.1 3.2 2 1 0 3 3 3 0 bZIP transcription factor HHH_2 PF12826.7 GAM41686.1 - 0.042 13.9 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF5082 PF16888.5 GAM41686.1 - 0.046 14.0 8.3 5.1 7.4 2.0 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) DUF848 PF05852.11 GAM41686.1 - 0.053 13.6 6.1 0.037 14.1 4.3 1.7 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Prefoldin_2 PF01920.20 GAM41686.1 - 0.054 13.5 7.0 1.3 9.0 0.0 3.2 2 1 1 3 3 3 0 Prefoldin subunit FlaC_arch PF05377.11 GAM41686.1 - 0.056 13.8 7.8 3.9 7.9 0.0 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.15 GAM41686.1 - 0.13 11.9 2.9 0.15 11.6 2.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4844 PF16133.5 GAM41686.1 - 0.15 12.6 2.9 0.43 11.1 2.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4844) DUF4094 PF13334.6 GAM41686.1 - 0.27 11.7 3.1 14 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) FapA PF03961.13 GAM41686.1 - 0.63 8.6 7.9 2.4 6.7 2.1 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A CCDC-167 PF15188.6 GAM41686.1 - 3.2 8.2 0.0 3.2 8.2 0.0 3.1 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 EMC3_TMCO1 PF01956.16 GAM41686.1 - 8.5 6.1 10.8 8.2 6.1 6.8 2.0 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like SAPS PF04499.15 GAM41687.1 - 3.9e-201 669.1 0.2 3.9e-201 669.1 0.2 2.9 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein Complex1_51K PF01512.17 GAM41688.1 - 2.6e-46 157.3 0.0 4.2e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 GAM41688.1 - 6.4e-29 99.9 0.3 1.4e-28 98.8 0.3 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 GAM41688.1 - 2.4e-08 33.7 0.0 5.7e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 SLBB domain SET PF00856.28 GAM41688.1 - 0.0086 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 SET domain DUF3568 PF12092.8 GAM41688.1 - 1.1 9.4 3.2 0.37 10.9 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) Swi5 PF07061.11 GAM41689.1 - 0.0093 16.0 6.0 0.16 12.1 0.0 2.5 3 0 0 3 3 3 2 Swi5 LPD22 PF18834.1 GAM41689.1 - 0.035 14.3 0.5 11 6.3 0.0 2.6 2 1 0 2 2 2 0 Large polyvalent protein associated domain 22 UFC1 PF08694.11 GAM41689.1 - 0.041 13.5 1.6 0.41 10.3 0.2 2.1 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 FapA PF03961.13 GAM41689.1 - 0.075 11.6 2.5 0.1 11.2 2.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2968 PF11180.8 GAM41689.1 - 0.1 12.2 0.2 0.1 12.2 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Cluap1 PF10234.9 GAM41689.1 - 0.12 11.7 6.9 0.89 8.9 6.9 1.9 1 1 0 1 1 1 0 Clusterin-associated protein-1 THOC7 PF05615.13 GAM41689.1 - 0.13 12.5 7.8 7.8 6.8 0.0 2.6 2 1 1 3 3 3 0 Tho complex subunit 7 AAA_13 PF13166.6 GAM41689.1 - 0.23 10.0 5.2 0.38 9.3 2.3 1.9 2 0 0 2 2 2 0 AAA domain Apolipoprotein PF01442.18 GAM41689.1 - 0.38 10.6 8.6 3.4 7.5 8.2 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain ZapB PF06005.12 GAM41689.1 - 0.6 10.6 7.2 14 6.2 0.1 2.7 2 1 0 2 2 2 0 Cell division protein ZapB FmiP_Thoc5 PF09766.9 GAM41689.1 - 1 8.6 9.4 0.12 11.6 5.3 1.5 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 DUF1542 PF07564.11 GAM41689.1 - 1.1 9.4 8.7 0.63 10.2 3.8 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) UPF0242 PF06785.11 GAM41689.1 - 2.4 8.2 8.7 0.71 9.9 4.8 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CdvA PF18822.1 GAM41689.1 - 2.6 7.9 11.4 3.1 7.7 5.8 2.7 2 1 0 2 2 2 0 CdvA-like coiled-coil domain MFS_1 PF07690.16 GAM41690.1 - 9.7e-27 93.8 12.3 9.7e-27 93.8 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PPP4R2 PF09184.11 GAM41690.1 - 0.0067 16.1 8.5 0.0093 15.6 8.5 1.2 1 0 0 1 1 1 1 PPP4R2 Nop14 PF04147.12 GAM41690.1 - 0.41 8.8 18.8 0.6 8.3 18.8 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleo_P87 PF07267.11 GAM41690.1 - 0.79 8.5 2.7 1.1 8.0 2.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAM176 PF14851.6 GAM41690.1 - 1.5 8.5 9.0 3.9 7.1 9.0 1.7 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.12 GAM41690.1 - 2 8.1 21.0 4.5 6.9 19.7 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SGT1 PF07093.11 GAM41690.1 - 4.1 5.7 11.1 5.6 5.3 11.1 1.1 1 0 0 1 1 1 0 SGT1 protein SDA1 PF05285.12 GAM41690.1 - 5 6.5 20.8 8.2 5.8 20.8 1.2 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.11 GAM41690.1 - 5.5 7.0 10.4 11 6.0 10.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Sporozoite_P67 PF05642.11 GAM41690.1 - 6.3 4.7 10.0 9.3 4.2 10.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.9 GAM41690.1 - 7.4 5.6 27.4 12 4.9 27.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PI3K_1B_p101 PF10486.9 GAM41690.1 - 8.3 4.0 10.5 12 3.5 10.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nup96 PF12110.8 GAM41691.1 - 1.7e-80 270.3 0.3 2.6e-80 269.7 0.3 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 GAM41691.1 - 4.8e-51 172.8 0.0 8e-51 172.1 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 GAM41691.1 - 7.4e-09 36.3 83.4 2.9e-06 28.0 39.8 10.3 3 2 6 9 9 9 4 Nucleoporin FG repeat region AMP-binding PF00501.28 GAM41692.1 - 6.9e-88 295.0 0.1 8.5e-88 294.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM41692.1 - 1.8e-27 96.1 0.4 1.5e-25 90.0 0.4 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 GAM41692.1 - 1.2e-16 60.3 0.3 3.2e-16 59.0 0.3 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus GET2 PF08690.10 GAM41693.1 - 4.8e-17 62.6 0.0 7.6e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 GET complex subunit GET2 ketoacyl-synt PF00109.26 GAM41694.1 - 1.1e-69 234.9 0.0 2.7e-69 233.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAM41694.1 - 3.2e-32 111.0 0.7 8.4e-32 109.7 0.7 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 GAM41694.1 - 1.5e-26 92.1 0.0 5.9e-26 90.2 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Acyl_transf_1 PF00698.21 GAM41694.1 - 5.1e-19 68.9 0.0 2.9e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain PP-binding PF00550.25 GAM41694.1 - 8e-16 58.2 0.1 6e-15 55.3 0.1 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 GAM41694.1 - 3.6e-14 53.3 0.0 1.3e-13 51.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain SAT PF16073.5 GAM41694.1 - 4e-12 46.4 6.7 1.4e-08 34.8 0.2 4.1 2 1 1 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_23 PF13489.6 GAM41694.1 - 8e-11 42.0 0.0 2.6e-09 37.1 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain PS-DH PF14765.6 GAM41694.1 - 1e-10 41.4 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_25 PF13649.6 GAM41694.1 - 4.7e-10 40.0 0.0 2.2e-09 37.9 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM41694.1 - 5.1e-08 33.5 0.0 2.6e-06 28.0 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAM41694.1 - 7.6e-08 32.8 0.0 2.6e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 GAM41694.1 - 5.2e-06 26.0 0.3 1.8e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 GAM41694.1 - 1.7e-05 24.6 0.0 0.00022 21.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAM41694.1 - 0.014 15.2 0.0 0.065 13.0 0.0 2.1 2 0 0 2 2 2 0 Lysine methyltransferase ACP_syn_III PF08545.10 GAM41694.1 - 0.019 14.8 0.2 0.019 14.8 0.2 1.9 2 0 0 2 2 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_33 PF10017.9 GAM41694.1 - 0.081 12.1 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_28 PF02636.17 GAM41694.1 - 0.15 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 GAM41694.1 - 0.17 11.2 0.0 0.49 9.7 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family FSH1 PF03959.13 GAM41695.1 - 4.4e-27 95.1 0.0 6.3e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 GAM41695.1 - 7.9e-07 29.1 0.0 1.7e-05 24.8 0.0 2.3 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 GAM41695.1 - 0.00067 19.6 0.5 0.0013 18.7 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold PE-PPE PF08237.11 GAM41695.1 - 0.052 13.1 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain SdpI PF13630.6 GAM41696.1 - 5.6 7.2 6.5 1.5 9.0 2.1 2.3 2 0 0 2 2 2 0 SdpI/YhfL protein family Lactamase_B_2 PF12706.7 GAM41697.1 - 6.1e-30 104.3 0.0 7.3e-22 77.9 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAM41697.1 - 1.6e-09 37.9 0.0 4.7e-09 36.3 0.0 1.7 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAM41697.1 - 0.011 15.7 4.7 0.086 12.8 1.1 3.2 2 2 1 3 3 3 0 Metallo-beta-lactamase superfamily GDPD PF03009.17 GAM41698.1 - 1.2e-32 113.7 0.0 1.9e-26 93.4 0.0 2.7 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family C2 PF00168.30 GAM41698.1 - 4.4e-29 100.8 0.0 8.5e-17 61.3 0.0 2.6 2 0 0 2 2 2 2 C2 domain GDPD_2 PF13653.6 GAM41698.1 - 0.11 13.0 1.7 0.17 12.4 0.1 2.3 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Aminotran_1_2 PF00155.21 GAM41699.1 - 6.2e-70 236.2 0.0 7.1e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAM41699.1 - 5e-05 22.0 0.0 9e-05 21.2 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 GAM41699.1 - 0.00072 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 GAM41699.1 - 0.0071 15.3 0.0 0.016 14.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAM41699.1 - 0.021 14.1 0.1 0.087 12.1 0.1 1.8 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Zn_clus PF00172.18 GAM41700.1 - 1.3 9.2 7.8 2.4 8.3 7.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MgsA_C PF12002.8 GAM41701.1 - 8.9e-59 198.2 0.1 1.5e-58 197.4 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 GAM41701.1 - 5.6e-23 81.1 0.4 2.2e-22 79.2 0.1 2.1 2 0 0 2 2 2 1 AAA C-terminal domain AAA PF00004.29 GAM41701.1 - 8.7e-13 48.8 0.1 2e-12 47.7 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAM41701.1 - 9.5e-10 38.4 0.0 1.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 GAM41701.1 - 1e-05 25.1 0.2 0.019 14.4 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAM41701.1 - 0.00011 22.3 0.3 0.0041 17.1 0.1 2.7 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 GAM41701.1 - 0.00046 19.9 0.1 0.027 14.2 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 GAM41701.1 - 0.00063 20.2 0.1 0.14 12.5 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 GAM41701.1 - 0.00063 19.9 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 GAM41701.1 - 0.0025 17.6 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAM41701.1 - 0.0031 17.3 0.0 0.0062 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAM41701.1 - 0.0051 17.1 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 GAM41701.1 - 0.006 15.8 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 GAM41701.1 - 0.014 15.7 0.3 0.031 14.6 0.3 1.6 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 GAM41701.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 GAM41701.1 - 0.016 15.2 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 GAM41701.1 - 0.024 13.8 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain SKI PF01202.22 GAM41701.1 - 0.063 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Shikimate kinase ResIII PF04851.15 GAM41701.1 - 0.095 12.7 1.2 6 6.8 0.0 2.5 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 GAM41701.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 GAM41701.1 - 0.21 11.3 0.5 0.43 10.3 0.1 1.7 2 0 0 2 2 2 0 AAA domain zf-Di19 PF05605.12 GAM41701.1 - 0.29 11.4 1.0 0.56 10.5 1.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DEAD PF00270.29 GAM41702.1 - 1.2e-48 165.2 0.0 1.9e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM41702.1 - 5.3e-30 104.0 0.2 1.7e-28 99.1 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GAM41702.1 - 1.8e-05 24.1 0.2 5.7e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 GAM41702.1 - 0.00041 20.4 0.0 0.0013 18.8 0.0 1.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAM41702.1 - 0.014 15.8 0.0 0.04 14.3 0.0 1.8 2 1 0 2 2 2 0 AAA domain EF-hand_7 PF13499.6 GAM41703.1 - 1.6e-16 60.5 2.5 2.7e-10 40.6 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAM41703.1 - 4.4e-15 54.0 0.7 1.5e-05 24.2 0.0 3.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GAM41703.1 - 8.2e-14 50.3 4.6 6.8e-06 25.6 0.1 3.8 4 1 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 GAM41703.1 - 4.3e-11 42.5 3.4 1.7e-08 34.2 0.2 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GAM41703.1 - 0.0017 17.7 1.1 1.5 8.4 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 GAM41703.1 - 0.042 13.8 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF3572 PF12096.8 GAM41703.1 - 0.048 13.9 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) EFhand_Ca_insen PF08726.10 GAM41703.1 - 0.15 12.1 0.1 0.59 10.3 0.0 2.0 2 0 0 2 2 2 0 Ca2+ insensitive EF hand DUF4106 PF13388.6 GAM41703.1 - 5.2 6.2 12.6 1.7 7.8 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) Reprolysin_5 PF13688.6 GAM41704.1 - 6.7e-61 205.9 9.3 6.7e-61 205.9 9.3 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAM41704.1 - 3.1e-48 164.1 4.9 5.5e-48 163.3 4.9 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 GAM41704.1 - 1e-46 159.3 4.6 1e-46 159.3 4.6 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 GAM41704.1 - 8e-17 61.8 31.8 8e-17 61.8 31.8 4.6 3 1 1 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 GAM41704.1 - 1.4e-10 41.7 0.6 4.8e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 GAM41704.1 - 2.9e-06 27.7 11.7 2.9e-06 27.7 11.7 4.9 1 1 2 3 3 3 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 GAM41704.1 - 0.0026 18.0 0.0 0.0052 17.0 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M66 PF10462.9 GAM41704.1 - 0.049 12.6 0.1 0.093 11.7 0.1 1.4 1 0 0 1 1 1 0 Peptidase M66 MFS_1 PF07690.16 GAM41705.1 - 5.8e-26 91.2 30.5 5.8e-26 91.2 30.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM41705.1 - 9.5e-07 28.0 15.8 9.5e-07 28.0 15.8 3.2 3 1 0 3 3 3 1 Sugar (and other) transporter Fungal_trans PF04082.18 GAM41706.1 - 5.5e-08 32.2 0.7 8.1e-08 31.6 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.13 GAM41707.1 - 3.1e-07 30.9 0.0 7.6e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 GAM41707.1 - 4.4e-07 29.0 0.0 0.22 10.2 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 GAM41707.1 - 0.042 14.2 0.0 0.13 12.7 0.0 1.8 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase FAD_binding_3 PF01494.19 GAM41708.1 - 1.7e-23 83.5 0.0 4.5e-23 82.0 0.0 1.7 2 1 0 2 2 2 1 FAD binding domain ADC PF06314.11 GAM41708.1 - 6.2e-11 42.3 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.6 GAM41708.1 - 7.4e-08 32.5 0.3 2.2e-07 31.0 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM41708.1 - 4.2e-07 29.5 0.1 8.6e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM41708.1 - 2.9e-05 23.4 0.3 4.7e-05 22.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM41708.1 - 2.9e-05 23.8 1.3 0.00023 20.9 1.8 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 GAM41708.1 - 0.00068 18.6 0.7 0.0032 16.4 0.2 2.1 1 1 1 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 GAM41708.1 - 0.002 17.5 0.1 0.0034 16.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM41708.1 - 0.0028 16.4 0.7 0.0094 14.7 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 GAM41708.1 - 0.0045 17.5 0.3 0.018 15.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM41708.1 - 0.0052 15.9 0.1 0.007 15.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 GAM41708.1 - 0.017 14.4 0.1 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 GAM41708.1 - 0.059 12.7 0.3 0.12 11.7 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 GAM41708.1 - 0.063 12.5 1.6 0.16 11.2 0.6 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cupin_2 PF07883.11 GAM41709.1 - 2e-07 30.6 0.0 3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 GAM41709.1 - 0.016 14.8 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PepX_C PF08530.10 GAM41710.1 - 1.6e-46 159.1 0.0 2.5e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 GAM41710.1 - 4.6e-41 141.2 1.1 7e-41 140.6 1.1 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 GAM41710.1 - 0.0021 17.4 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 M20_dimer PF07687.14 GAM41711.1 - 2.3e-16 59.7 0.1 4.8e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 GAM41711.1 - 2.6e-16 59.9 0.4 1.6e-15 57.4 0.4 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 GAM41711.1 - 0.0022 17.7 0.0 0.0055 16.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 MFS_1 PF07690.16 GAM41712.1 - 4.6e-28 98.1 26.1 4.6e-28 98.1 26.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_S9 PF00326.21 GAM41713.1 - 5.6e-36 124.0 0.0 8.4e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 GAM41713.1 - 1.2e-15 56.9 5.3 2.8e-07 30.3 0.0 4.6 4 0 0 4 4 4 4 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.13 GAM41713.1 - 6.4e-07 29.4 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM41713.1 - 0.00043 19.6 0.2 0.071 12.4 0.2 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 GAM41713.1 - 0.0021 17.6 0.0 0.01 15.4 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9_N PF02897.15 GAM41713.1 - 0.0025 16.7 0.1 0.25 10.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain DPPIV_N PF00930.21 GAM41713.1 - 0.0025 16.6 0.1 6 5.5 0.0 3.8 4 0 0 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_2 PF02230.16 GAM41713.1 - 0.013 15.3 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase TruB_C PF09142.11 GAM41713.1 - 0.018 14.8 0.0 0.78 9.6 0.0 2.6 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Abhydrolase_1 PF00561.20 GAM41713.1 - 0.02 14.5 0.4 0.065 12.9 0.7 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold COesterase PF00135.28 GAM41713.1 - 0.11 11.3 0.2 0.17 10.7 0.2 1.1 1 0 0 1 1 1 0 Carboxylesterase family Esterase_phd PF10503.9 GAM41714.1 - 0.00031 20.3 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 GAM41714.1 - 0.032 13.5 0.0 0.15 11.3 0.0 1.8 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Aldedh PF00171.22 GAM41715.1 - 3.2e-12 45.7 0.1 2.4e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family LsmAD PF06741.13 GAM41715.1 - 0.1 13.2 0.3 0.24 12.0 0.3 1.6 1 0 0 1 1 1 0 LsmAD domain zf-H2C2_2 PF13465.6 GAM41716.1 - 4.2e-09 36.4 10.7 9.4e-09 35.3 2.7 3.2 3 0 0 3 3 3 1 Zinc-finger double domain Fungal_trans PF04082.18 GAM41716.1 - 1.9e-08 33.7 0.3 3.8e-08 32.7 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAM41716.1 - 1.1e-06 28.7 9.2 0.001 19.4 3.4 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM41716.1 - 4.4e-06 27.1 7.5 0.0045 17.7 2.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_clus PF00172.18 GAM41716.1 - 6.6e-06 26.2 9.2 6.6e-06 26.2 9.2 2.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LigB PF02900.18 GAM41717.1 - 1.2e-16 60.6 0.0 1.5e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MFS_1 PF07690.16 GAM41718.1 - 2.5e-19 69.4 24.1 2.5e-19 69.4 24.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4118 PF13493.6 GAM41718.1 - 0.046 13.5 0.6 0.046 13.5 0.6 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4118) Fzo_mitofusin PF04799.13 GAM41718.1 - 2.3 7.8 3.2 4.8 6.7 3.2 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF4191 PF13829.6 GAM41718.1 - 9.5 5.5 8.1 0.48 9.7 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) PhyH PF05721.13 GAM41719.1 - 0.00024 21.4 0.0 0.00085 19.6 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 GAM41719.1 - 0.00037 19.4 0.4 0.14 10.9 0.0 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) FAA_hydrolase PF01557.18 GAM41720.1 - 5.2e-54 183.2 0.0 8.5e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Peptidase_S15 PF02129.18 GAM41720.1 - 1.1e-38 133.4 0.1 1.4e-36 126.5 0.0 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 GAM41720.1 - 1.7e-29 103.4 0.0 2.5e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain FAA_hydrolase_N PF09298.11 GAM41720.1 - 7.3e-20 71.2 0.0 1.2e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal GFA PF04828.14 GAM41722.1 - 4.8e-15 55.7 8.8 5.3e-08 33.1 1.5 3.4 2 1 1 3 3 3 3 Glutathione-dependent formaldehyde-activating enzyme Bd3614-deam PF14439.6 GAM41722.1 - 0.029 14.5 0.7 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Bd3614-like deaminase VWA_N2 PF16164.5 GAM41722.1 - 3 8.1 10.1 0.86 9.8 0.2 2.8 2 2 0 2 2 2 0 VWA N-terminal DUF4636 PF15468.6 GAM41723.1 - 0.081 12.6 3.2 0.13 12.0 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) CCDC106 PF15794.5 GAM41723.1 - 0.21 11.3 6.6 0.3 10.8 6.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 GAM41723.1 - 0.23 9.7 8.8 0.25 9.6 7.9 1.4 2 0 0 2 2 2 0 CDC45-like protein MFMR_assoc PF16596.5 GAM41723.1 - 0.29 11.6 10.6 0.68 10.4 10.6 1.7 1 0 0 1 1 1 0 Disordered region downstream of MFMR NAM-associated PF14303.6 GAM41723.1 - 2.2 9.0 11.6 2.5 8.8 10.6 1.7 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain Apt1 PF10351.9 GAM41723.1 - 2.9 6.6 8.5 3.8 6.3 8.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain IMS PF00817.20 GAM41724.1 - 7.9e-39 133.0 0.0 1.8e-38 131.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 GAM41724.1 - 5.8e-16 59.3 0.2 2.6e-15 57.2 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 GAM41724.1 - 0.01 16.1 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif HHH_5 PF14520.6 GAM41724.1 - 0.069 13.8 0.0 0.19 12.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain zf_UBZ PF18439.1 GAM41724.1 - 0.071 12.7 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger HHH PF00633.23 GAM41724.1 - 0.13 12.2 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Fungal_lectin PF07938.12 GAM41727.1 - 4.5e-10 39.4 1.1 7.2e-10 38.7 1.0 1.4 1 1 0 1 1 1 1 Fungal fucose-specific lectin ACC_central PF08326.12 GAM41730.1 - 0.23 9.6 0.2 0.67 8.1 0.0 1.7 2 0 0 2 2 2 0 Acetyl-CoA carboxylase, central region Ald_Xan_dh_C2 PF02738.18 GAM41731.1 - 1.7e-205 683.6 4.3 2.4e-205 683.1 4.3 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 GAM41731.1 - 3.6e-46 157.0 0.0 8.7e-46 155.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 GAM41731.1 - 3.3e-33 114.3 0.0 7.2e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 GAM41731.1 - 1.9e-30 105.0 0.1 9.9e-30 102.8 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 GAM41731.1 - 2.5e-29 101.1 0.0 5.5e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 GAM41731.1 - 4.6e-07 29.7 0.1 4.6e-07 29.7 0.1 2.3 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain AF0941-like PF14591.6 GAM41731.1 - 0.25 11.9 1.2 0.96 10.0 0.1 2.2 2 0 0 2 2 2 0 AF0941-like DUF3328 PF11807.8 GAM41732.1 - 0.48 10.2 2.2 10 5.8 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DIM1 PF02966.16 GAM41734.1 - 6.5e-67 223.4 0.1 7.4e-67 223.2 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 GAM41734.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin SNF2_N PF00176.23 GAM41736.1 - 1.9e-41 142.0 0.0 3.5e-37 128.0 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM41736.1 - 6.6e-07 29.7 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UPF0184 PF03670.13 GAM41736.1 - 0.084 13.3 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Ribosomal_S6e PF01092.19 GAM41737.1 - 2.2e-57 192.5 0.0 5.2e-57 191.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Pribosyltran_N PF13793.6 GAM41738.1 - 4.8e-45 152.2 1.5 1.3e-43 147.6 0.1 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAM41738.1 - 3.9e-41 141.1 5.8 3.2e-35 121.8 1.7 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAM41738.1 - 9.8e-19 67.4 1.0 3.8e-17 62.3 0.5 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAM41738.1 - 7e-05 22.4 0.3 0.00014 21.3 0.3 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF913 PF06025.12 GAM41739.1 - 1.5e-130 435.5 0.0 1.5e-130 435.5 0.0 5.7 5 1 0 5 5 5 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 GAM41739.1 - 4.8e-105 351.9 9.4 4.8e-105 351.9 9.4 2.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) HECT PF00632.25 GAM41739.1 - 3.5e-95 319.0 0.0 9.4e-95 317.6 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 GAM41739.1 - 3.5e-30 102.5 21.6 2.3e-11 42.7 2.6 4.3 3 0 0 3 3 3 3 Ubiquitin binding region V-ATPase_H_N PF03224.14 GAM41739.1 - 0.1 11.9 0.7 0.65 9.2 0.1 2.7 2 0 0 2 2 2 0 V-ATPase subunit H Glyco_transf_34 PF05637.12 GAM41740.1 - 2.6e-61 207.4 0.0 3.8e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Steroid_dh PF02544.16 GAM41740.1 - 1.2e-31 109.7 0.6 4.2e-31 108.0 0.2 2.0 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 GAM41740.1 - 0.0079 16.6 1.0 0.018 15.4 0.2 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 GAM41740.1 - 0.031 13.8 0.1 0.055 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DUF4407 PF14362.6 GAM41740.1 - 0.67 9.2 5.5 0.083 12.2 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ribosomal_L28 PF00830.19 GAM41741.1 - 7.6e-15 54.9 1.1 7.6e-15 54.9 1.1 1.6 2 0 0 2 2 2 1 Ribosomal L28 family DHHA2 PF02833.14 GAM41741.1 - 0.097 12.8 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 DHHA2 domain TIP49 PF06068.13 GAM41742.1 - 1.4e-163 544.1 0.0 1.7e-163 543.9 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 GAM41742.1 - 2.9e-23 81.8 0.0 1.6e-22 79.4 0.0 2.2 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 GAM41742.1 - 7.5e-11 42.6 0.2 5.1e-07 30.2 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAM41742.1 - 5e-10 39.3 0.0 1.1e-06 28.4 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAM41742.1 - 6.4e-05 23.2 0.1 0.39 11.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAM41742.1 - 0.0008 19.8 0.2 0.0066 16.9 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 GAM41742.1 - 0.00086 19.7 1.3 0.064 13.6 0.3 2.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAM41742.1 - 0.00089 19.3 0.1 0.18 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 GAM41742.1 - 0.0023 17.7 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 GAM41742.1 - 0.0026 18.0 0.1 0.0054 17.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAM41742.1 - 0.0065 15.8 0.2 0.015 14.6 0.2 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.6 GAM41742.1 - 0.0075 15.9 0.1 0.017 14.7 0.1 1.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAM41742.1 - 0.022 14.2 0.1 0.75 9.1 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAM41742.1 - 0.053 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 GAM41742.1 - 0.063 12.6 0.1 0.16 11.3 0.1 1.6 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.9 GAM41742.1 - 0.065 12.5 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 GAM41742.1 - 0.071 13.7 0.0 0.25 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 GAM41742.1 - 0.088 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_7 PF12775.7 GAM41742.1 - 0.12 11.9 0.3 0.41 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region V-SNARE PF05008.15 GAM41743.1 - 3.5e-22 78.5 5.0 3.5e-22 78.5 5.0 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 GAM41743.1 - 3.8e-15 55.9 2.6 3.8e-15 55.9 2.6 2.6 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Thump_like PF18096.1 GAM41743.1 - 0.00099 19.0 0.0 0.0028 17.5 0.0 1.7 2 0 0 2 2 2 1 THUMP domain-like Acyl-CoA_dh_2 PF08028.11 GAM41743.1 - 0.025 14.8 0.1 0.043 14.1 0.1 1.6 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Prominin PF05478.11 GAM41743.1 - 0.22 9.4 1.6 0.37 8.7 0.2 1.7 2 0 0 2 2 2 0 Prominin zf-C4H2 PF10146.9 GAM41743.1 - 1 9.6 8.1 5.6 7.2 8.0 2.1 1 1 0 1 1 1 0 Zinc finger-containing protein Exonuc_VII_L PF02601.15 GAM41743.1 - 1.4 8.5 11.9 8.5 5.8 11.9 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF2407_C PF13373.6 GAM41744.1 - 6.7e-44 149.5 0.1 1.2e-43 148.6 0.1 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 GAM41744.1 - 5.3e-33 113.7 0.0 9.2e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 GAM41744.1 - 0.0001 22.0 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 GAM41744.1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Fe-S_biosyn PF01521.20 GAM41745.1 - 1.7e-20 73.2 0.0 3.2e-20 72.4 0.0 1.4 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis DUF1741 PF08427.10 GAM41746.1 - 1.1e-92 309.9 0.3 1.8e-92 309.3 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) MRG PF05712.13 GAM41747.1 - 3.4e-58 196.2 2.5 4.6e-58 195.8 2.5 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 GAM41747.1 - 1.3e-10 41.0 2.7 2.8e-10 39.9 2.7 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GAM41747.1 - 0.00026 20.9 1.2 0.00077 19.3 1.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.17 GAM41747.1 - 0.01 16.2 0.1 0.026 14.9 0.1 1.6 1 0 0 1 1 1 0 PWWP domain Cnl2_NKP2 PF09447.10 GAM41748.1 - 1.1e-26 92.7 1.5 2.3e-26 91.7 1.5 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein DUF948 PF06103.11 GAM41748.1 - 0.068 13.4 1.5 0.11 12.8 0.4 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Mod_r PF07200.13 GAM41748.1 - 0.9 9.6 5.0 2.8 8.0 5.0 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Ctf8 PF09696.10 GAM41749.1 - 5.3e-46 156.5 0.0 6.5e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Dabb PF07876.12 GAM41750.1 - 6.2e-10 39.6 0.0 6.9e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Chalcone_N PF18232.1 GAM41750.1 - 0.0088 16.4 0.0 0.01 16.2 0.0 1.1 1 0 0 1 1 1 1 Chalcone isomerase N-terminal domain RabGAP-TBC PF00566.18 GAM41751.1 - 9.8e-47 159.4 0.0 4.3e-46 157.3 0.0 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain APG6_N PF17675.1 GAM41751.1 - 0.0028 18.2 7.2 0.0028 18.2 7.2 2.8 3 0 0 3 3 3 1 Apg6 coiled-coil region UPF0242 PF06785.11 GAM41751.1 - 0.13 12.3 21.8 0.32 11.1 21.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SHE3 PF17078.5 GAM41751.1 - 0.44 10.2 15.8 0.82 9.3 15.8 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 HALZ PF02183.18 GAM41751.1 - 0.86 9.9 4.8 0.36 11.1 0.9 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Mago_nashi PF02792.14 GAM41751.1 - 2.2 8.4 6.5 0.23 11.6 0.9 2.0 1 1 1 2 2 2 0 Mago nashi protein PPTA PF01239.22 GAM41752.1 - 1.3e-33 113.7 22.3 3.6e-08 32.9 0.1 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF1016_N PF17761.1 GAM41752.1 - 0.015 15.5 1.7 0.078 13.1 1.5 2.2 1 1 0 1 1 1 0 DUF1016 N-terminal domain PhoD_N PF16655.5 GAM41752.1 - 0.051 14.1 0.1 0.24 12.0 0.0 2.0 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain DUF469 PF04320.14 GAM41752.1 - 0.27 12.1 3.2 1.2 10.1 0.1 2.8 3 1 0 3 3 3 0 Protein with unknown function (DUF469) DUF3950 PF13132.6 GAM41752.1 - 0.5 10.2 1.9 2 8.2 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3950) Utp12 PF04003.12 GAM41753.1 - 2.8e-22 79.1 0.0 4.7e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family DUF3157 PF11355.8 GAM41753.1 - 0.0022 17.6 0.2 0.39 10.3 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3157) ANAPC4_WD40 PF12894.7 GAM41753.1 - 0.17 12.2 0.2 29 5.1 0.0 4.1 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.13 GAM41753.1 - 0.18 11.7 41.2 0.51 10.3 6.0 2.8 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit Bromodomain PF00439.25 GAM41754.1 - 4.2e-41 138.9 0.4 4e-20 71.7 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 GAM41754.1 - 9.7e-19 67.3 2.2 3e-18 65.7 1.5 2.3 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Sin3_corepress PF08295.12 GAM41754.1 - 0.24 11.5 5.6 0.097 12.7 2.1 2.1 2 0 0 2 2 2 0 Sin3 family co-repressor V_ATPase_I PF01496.19 GAM41754.1 - 0.57 8.0 7.2 0.91 7.4 7.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3573 PF12097.8 GAM41754.1 - 1.6 7.5 7.4 2.6 6.8 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HAUS4 PF14735.6 GAM41755.1 - 5.4e-11 42.7 1.2 9.1e-11 41.9 1.2 1.5 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 Use1 PF09753.9 GAM41755.1 - 0.032 13.9 0.2 0.063 13.0 0.2 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 Seryl_tRNA_N PF02403.22 GAM41755.1 - 0.056 13.7 1.7 0.58 10.4 0.2 2.2 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-CSL PF05207.13 GAM41756.1 - 4.8e-22 77.4 0.3 6.4e-22 77.1 0.3 1.2 1 0 0 1 1 1 1 CSL zinc finger Frataxin_Cyay PF01491.16 GAM41757.1 - 0.0031 17.6 0.2 0.0056 16.7 0.2 1.4 1 0 0 1 1 1 1 Frataxin-like domain Cmyb_C PF09316.10 GAM41757.1 - 0.044 13.4 0.1 0.048 13.3 0.1 1.1 1 0 0 1 1 1 0 C-myb, C-terminal DUF1730 PF08331.10 GAM41757.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) AKAP7_NLS PF10469.9 GAM41758.1 - 1.2e-18 67.8 0.0 2.3e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain HsbA PF12296.8 GAM41759.1 - 1.2e-26 93.5 7.4 1.2e-26 93.5 7.4 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Glyco_hydro_16 PF00722.21 GAM41760.1 - 5.9e-15 55.2 0.4 2.5e-14 53.2 0.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 GAM41760.1 - 1.5e-07 30.2 4.6 1.2e-05 24.0 0.5 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Sec6 PF06046.13 GAM41761.1 - 2.1e-172 574.5 5.3 2.8e-172 574.1 5.3 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 GAM41761.1 - 0.022 13.7 7.4 0.22 10.4 2.4 2.4 2 0 0 2 2 2 0 Vps53-like, N-terminal RPAP3_C PF13877.6 GAM41761.1 - 0.047 14.2 0.5 11 6.6 0.0 3.6 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 Laminin_II PF06009.12 GAM41761.1 - 0.055 13.5 1.0 0.12 12.3 0.5 1.8 1 1 0 1 1 1 0 Laminin Domain II LprI PF07007.12 GAM41761.1 - 0.19 12.4 0.1 0.19 12.4 0.1 3.2 3 1 1 4 4 4 0 Lysozyme inhibitor LprI FadA PF09403.10 GAM41761.1 - 7.8 7.1 8.9 23 5.6 1.0 3.0 2 1 0 2 2 2 0 Adhesion protein FadA Ribosomal_L30 PF00327.20 GAM41762.1 - 2.1e-11 43.5 0.2 2.8e-11 43.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Pyridoxal_deC PF00282.19 GAM41763.1 - 5.7e-18 64.8 0.0 9.2e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GAM41763.1 - 6e-06 25.5 0.0 3.3e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAM41763.1 - 0.0021 17.4 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family HMGL-like PF00682.19 GAM41764.1 - 5.3e-79 265.5 0.4 7.9e-79 264.9 0.4 1.3 1 0 0 1 1 1 1 HMGL-like Endonuc-BglII PF09195.11 GAM41764.1 - 0.082 12.7 0.0 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 Restriction endonuclease BglII PTH2 PF01981.16 GAM41766.1 - 1.3e-36 125.5 0.2 1.8e-36 124.9 0.2 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SART-1 PF03343.13 GAM41767.1 - 2e-191 637.8 63.8 2.3e-191 637.6 63.8 1.0 1 0 0 1 1 1 1 SART-1 family Aminotran_1_2 PF00155.21 GAM41768.1 - 1.3e-89 301.0 0.0 1.5e-89 300.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Hpt PF01627.23 GAM41769.1 - 5e-13 49.1 0.5 8.6e-13 48.4 0.1 1.6 2 0 0 2 2 2 1 Hpt domain IreB PF06135.12 GAM41769.1 - 0.085 13.1 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 IreB regulatory phosphoprotein MCU PF04678.13 GAM41770.1 - 6.9e-27 94.7 0.3 6.9e-27 94.7 0.3 2.6 2 1 0 3 3 3 1 Mitochondrial calcium uniporter DUF1281 PF06924.11 GAM41770.1 - 0.0073 15.9 0.4 0.013 15.1 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1281) dsrm PF00035.26 GAM41770.1 - 0.12 13.2 0.0 0.23 12.2 0.0 1.4 1 0 0 1 1 1 0 Double-stranded RNA binding motif Prenyltrans PF00432.21 GAM41771.1 - 1e-25 89.1 20.9 4.3e-05 23.2 1.0 6.4 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Peptidase_S64 PF08192.11 GAM41771.1 - 0.00012 20.8 0.0 0.00018 20.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 DUF4268 PF14088.6 GAM41771.1 - 0.038 13.9 0.0 7.2 6.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4268) SQHop_cyclase_N PF13249.6 GAM41771.1 - 0.044 12.9 0.0 1.7 7.7 0.0 2.2 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain Zn_clus PF00172.18 GAM41772.1 - 0.0033 17.5 7.7 0.0072 16.4 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.9 GAM41772.1 - 1.1 8.8 14.7 2 8.0 14.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pap_E4 PF02711.14 GAM41772.1 - 2.4 9.1 9.4 7.1 7.7 9.4 1.8 1 0 0 1 1 1 0 E4 protein ubiquitin PF00240.23 GAM41773.1 - 6.6e-84 275.7 17.9 1.6e-33 114.2 0.6 4.0 3 1 1 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 GAM41773.1 - 8.2e-37 124.9 13.0 1e-15 57.3 0.7 4.0 3 1 1 4 4 4 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAM41773.1 - 3.9e-14 52.9 6.8 0.00022 21.6 0.1 4.3 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 GAM41773.1 - 5.6e-08 32.6 0.3 0.015 15.2 0.1 2.5 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GAM41773.1 - 6.4e-08 32.9 1.8 0.0084 16.4 0.1 2.5 2 1 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAM41773.1 - 1.7e-07 31.3 0.8 0.068 13.3 0.0 3.6 3 2 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like Sde2_N_Ubi PF13019.6 GAM41773.1 - 2.3e-06 27.5 1.8 0.27 11.1 0.0 3.5 1 1 1 3 3 3 2 Silencing defective 2 N-terminal ubiquitin domain DUF2407 PF10302.9 GAM41773.1 - 3.7e-06 27.4 1.0 0.059 13.9 0.2 2.4 2 1 0 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAM41773.1 - 8.3e-06 25.8 14.6 7.2 6.7 0.5 5.8 5 1 1 6 6 6 0 Ubiquitin-like domain ACT_5 PF13710.6 GAM41773.1 - 0.00011 22.0 2.1 6.2 6.7 0.0 3.3 3 0 0 3 3 3 2 ACT domain Big_7 PF17957.1 GAM41773.1 - 0.00069 20.3 0.5 20 6.1 0.1 3.1 3 0 0 3 3 3 0 Bacterial Ig domain TmoB PF06234.12 GAM41773.1 - 0.0011 18.9 0.4 8 6.6 0.0 3.6 3 2 0 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) Methyltrans_RNA PF04452.14 GAM41773.1 - 0.0015 17.9 0.2 0.97 8.7 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase PDGLE PF13190.6 GAM41773.1 - 0.0017 18.2 2.4 0.87 9.5 0.1 3.4 1 1 1 3 3 3 1 PDGLE domain DUF3861 PF12977.7 GAM41773.1 - 0.0018 18.4 0.7 7.4 6.8 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) YcgR_2 PF12945.7 GAM41773.1 - 0.003 17.7 5.6 3.2 8.0 0.2 3.2 2 1 1 3 3 3 1 Flagellar protein YcgR UDP-g_GGTase PF06427.11 GAM41773.1 - 0.0055 16.8 1.4 3.6 7.8 0.0 3.2 3 1 1 4 4 3 1 UDP-glucose:Glycoprotein Glucosyltransferase NEAT PF05031.12 GAM41773.1 - 0.0063 17.1 1.9 0.2 12.3 0.5 2.3 1 1 1 2 2 2 2 Iron Transport-associated domain DUF2870 PF11069.8 GAM41773.1 - 0.025 15.0 0.0 18 5.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) DUF493 PF04359.14 GAM41773.1 - 0.032 14.8 0.1 85 3.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF493) ACT_4 PF13291.6 GAM41773.1 - 0.058 14.0 0.5 86 3.8 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF969 PF06149.12 GAM41773.1 - 0.061 12.7 0.0 13 5.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF969) ORF11CD3 PF10549.9 GAM41773.1 - 0.067 13.3 0.0 55 4.0 0.0 3.4 3 0 0 3 3 3 0 ORF11CD3 domain Sortase PF04203.13 GAM41773.1 - 0.081 12.7 0.8 19 5.1 0.1 2.9 1 1 1 3 3 3 0 Sortase domain Tash_PEST PF07708.11 GAM41773.1 - 0.1 12.8 18.4 4.1 7.7 1.5 3.3 3 0 0 3 3 3 0 Tash protein PEST motif PI3K_p85B PF02192.16 GAM41773.1 - 0.18 11.5 3.5 42 4.0 0.0 3.3 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain DMA PF03474.14 GAM41773.1 - 0.21 11.2 1.5 65 3.2 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif Myosin_N PF02736.19 GAM41773.1 - 3 7.7 7.1 69 3.4 0.0 4.3 4 0 0 4 4 3 0 Myosin N-terminal SH3-like domain FlgD_ig PF13860.6 GAM41773.1 - 4.6 7.2 5.6 1.1e+02 2.8 0.1 3.2 3 0 0 3 3 3 0 FlgD Ig-like domain BRAP2 PF07576.12 GAM41774.1 - 8.2e-35 119.0 0.0 1.4e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 GAM41774.1 - 4.7e-21 74.9 4.6 1.4e-20 73.4 4.6 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 GAM41774.1 - 5e-08 33.2 9.5 5e-08 33.2 9.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM41774.1 - 1.6e-05 24.7 9.7 1.6e-05 24.7 9.7 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM41774.1 - 0.00044 20.0 5.1 0.00044 20.0 5.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ZapB PF06005.12 GAM41774.1 - 0.00047 20.5 12.1 0.00061 20.2 1.1 2.5 1 1 1 2 2 2 1 Cell division protein ZapB zf-rbx1 PF12678.7 GAM41774.1 - 0.00073 19.8 7.1 0.00073 19.8 7.1 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAM41774.1 - 0.0011 18.6 5.7 0.0011 18.6 5.7 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAM41774.1 - 0.0012 18.8 5.5 0.0012 18.8 5.5 2.9 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAM41774.1 - 0.0013 18.6 8.8 0.0013 18.6 8.8 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM41774.1 - 0.0023 17.8 7.9 0.0023 17.8 7.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain GIT_CC PF16559.5 GAM41774.1 - 0.0029 17.5 3.1 0.055 13.3 1.1 2.5 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor zf-ANAPC11 PF12861.7 GAM41774.1 - 0.0091 16.0 5.2 0.026 14.6 5.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 GAM41774.1 - 0.012 15.5 3.4 0.012 15.5 3.4 2.0 2 0 0 2 2 1 0 zf-RING of BARD1-type protein JAKMIP_CC3 PF16034.5 GAM41774.1 - 0.057 13.4 9.1 0.11 12.4 9.1 1.4 1 0 0 1 1 1 0 JAKMIP CC3 domain Prok-RING_4 PF14447.6 GAM41774.1 - 0.08 12.8 18.4 0.023 14.5 9.0 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Cep57_MT_bd PF06657.13 GAM41774.1 - 0.14 12.6 3.3 1.1 9.7 0.4 2.9 3 0 0 3 3 2 0 Centrosome microtubule-binding domain of Cep57 Exonuc_VII_L PF02601.15 GAM41774.1 - 0.19 11.3 4.9 0.34 10.5 4.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc29 PF17082.5 GAM41774.1 - 0.24 11.2 4.7 0.058 13.2 0.8 2.0 2 0 0 2 2 2 0 Spindle Pole Component 29 DUF2959 PF11172.8 GAM41774.1 - 0.54 10.4 9.9 1 9.5 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) FAM76 PF16046.5 GAM41774.1 - 0.77 9.1 6.4 1.9 7.8 6.4 1.6 1 0 0 1 1 1 0 FAM76 protein DUF745 PF05335.13 GAM41774.1 - 1.7 8.3 16.9 64 3.2 16.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF745) zf-RING_4 PF14570.6 GAM41774.1 - 1.8 8.4 6.1 4.1 7.3 6.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CENP-F_leu_zip PF10473.9 GAM41774.1 - 4.5 7.3 18.0 0.47 10.5 13.3 1.8 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ALS2CR11 PF15729.5 GAM41774.1 - 5.3 6.1 6.6 0.57 9.3 1.3 1.7 1 1 1 2 2 2 0 Amyotrophic lateral sclerosis 2 candidate 11 TPR_MLP1_2 PF07926.12 GAM41774.1 - 6.3 6.9 22.3 13 5.9 21.9 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein E1-E2_ATPase PF00122.20 GAM41775.1 - 1.6e-40 138.6 18.0 1.6e-33 115.7 0.9 3.5 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAM41775.1 - 4.8e-29 101.4 2.5 4.8e-29 101.4 2.5 2.4 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 GAM41775.1 - 1.6e-23 82.6 0.1 1e-22 80.0 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM41775.1 - 1.7e-16 61.2 1.2 5.4e-15 56.2 1.2 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM41775.1 - 2e-13 49.8 0.0 5.6e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM41775.1 - 6.3e-06 26.1 1.4 0.012 15.4 0.9 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S4 PF01479.25 GAM41775.1 - 0.058 13.1 0.4 0.14 11.9 0.4 1.6 1 0 0 1 1 1 0 S4 domain HAD PF12710.7 GAM41775.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Zn_clus PF00172.18 GAM41776.1 - 7.9e-07 29.1 8.9 1.7e-06 28.0 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAM41776.1 - 0.00042 19.2 0.1 0.00088 18.2 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.22 GAM41777.1 - 4.4e-22 79.2 0.0 6.8e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 GAM41777.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.16 GAM41777.1 - 0.068 13.8 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Methyltransf_23 PF13489.6 GAM41778.1 - 3.4e-17 62.8 0.0 6.6e-17 61.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM41778.1 - 2.2e-12 47.5 0.0 6.2e-12 46.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM41778.1 - 6.6e-12 46.0 0.0 2.9e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM41778.1 - 2.2e-11 44.4 0.0 6.1e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM41778.1 - 4e-08 33.2 0.0 5.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAM41778.1 - 0.0014 18.0 0.0 0.082 12.2 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase DXP_redisom_C PF08436.12 GAM41778.1 - 0.0022 18.1 0.0 0.0063 16.7 0.0 1.8 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain CheR PF01739.18 GAM41778.1 - 0.024 14.1 0.0 2.4 7.6 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 GAM41778.1 - 0.089 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family zf-C2H2 PF00096.26 GAM41779.1 - 2.4e-19 68.6 27.4 3.1e-05 24.2 1.7 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM41779.1 - 2.6e-17 62.3 23.6 1.2e-06 28.7 1.5 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAM41779.1 - 1.6e-10 40.9 25.1 0.0035 18.1 1.3 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAM41779.1 - 7.9e-06 26.0 2.3 0.76 10.1 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 GAM41779.1 - 0.00012 22.6 4.6 0.1 13.3 0.4 2.9 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-met PF12874.7 GAM41779.1 - 0.00028 21.1 12.1 0.038 14.4 0.2 4.0 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 GAM41779.1 - 0.011 15.9 0.3 2.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 GAM41779.1 - 0.017 14.9 0.8 0.017 14.9 0.8 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-MYST PF17772.1 GAM41779.1 - 0.054 13.1 1.4 3.9 7.1 0.0 2.9 3 0 0 3 3 3 0 MYST family zinc finger domain zf_UBZ PF18439.1 GAM41779.1 - 0.11 12.1 2.2 0.98 9.1 0.2 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Yippee-Mis18 PF03226.14 GAM41779.1 - 0.23 11.7 2.1 14 5.9 0.1 2.3 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly C1_4 PF07975.12 GAM41779.1 - 0.64 10.3 5.7 0.74 10.1 0.2 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain LIM PF00412.22 GAM41779.1 - 0.88 9.8 5.1 15 5.9 0.0 3.0 2 1 1 3 3 3 0 LIM domain DUF4764 PF15961.5 GAM41779.1 - 6.3 5.4 8.7 51 2.3 8.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4764) HNH PF01844.23 GAM41779.1 - 7.4 6.8 7.5 6.8 7.0 0.1 3.5 4 0 0 4 4 4 0 HNH endonuclease Zn_ribbon_recom PF13408.6 GAM41779.1 - 8.1 7.0 7.5 2.5 8.7 3.0 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-CRD PF17979.1 GAM41779.1 - 9.4 6.3 9.0 2.8 8.0 1.9 2.1 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions DUF155 PF02582.14 GAM41780.1 - 1.5e-53 181.5 0.1 2.2e-53 181.0 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF5082 PF16888.5 GAM41781.1 - 0.039 14.2 4.8 1.4 9.3 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) AIRC PF00731.20 GAM41782.1 - 2.2e-59 199.3 0.7 4.5e-59 198.3 0.7 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 GAM41782.1 - 1.4e-53 181.0 0.0 3.3e-53 179.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 GAM41782.1 - 1.4e-14 53.5 0.1 3e-14 52.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 GAM41782.1 - 1.5e-05 24.6 0.2 4.5e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 GAM41782.1 - 3.9e-05 23.3 0.0 0.00027 20.6 0.0 2.3 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus PrpR_N PF06506.11 GAM41782.1 - 5.6e-05 22.8 0.4 0.0086 15.7 0.1 3.0 3 0 0 3 3 3 1 Propionate catabolism activator 2-Hacid_dh_C PF02826.19 GAM41782.1 - 0.00075 18.9 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAM41782.1 - 0.00086 18.7 0.0 0.0019 17.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 GAM41782.1 - 0.0026 17.7 0.1 0.0074 16.2 0.1 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAM41782.1 - 0.0073 16.5 0.1 0.021 15.0 0.1 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 GAM41782.1 - 0.011 16.3 0.4 0.039 14.5 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 GAM41782.1 - 0.062 12.8 0.1 0.098 12.1 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family XdhC_C PF13478.6 GAM41782.1 - 0.072 13.6 0.1 0.29 11.7 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain ATP-grasp_3 PF02655.14 GAM41782.1 - 0.096 12.7 0.0 0.27 11.3 0.0 2.0 1 1 0 1 1 1 0 ATP-grasp domain NAD_Gly3P_dh_N PF01210.23 GAM41782.1 - 0.15 12.0 0.7 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.6 GAM41782.1 - 0.35 10.7 2.1 0.35 10.7 0.4 1.8 2 0 0 2 2 2 0 NAD(P)H-binding PPP4R2 PF09184.11 GAM41783.1 - 1.8e-10 40.9 2.2 7.2e-10 38.9 2.2 2.1 1 1 0 1 1 1 1 PPP4R2 GATA PF00320.27 GAM41784.1 - 1.1e-15 57.0 5.9 2.1e-15 56.0 5.9 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 GAM41784.1 - 1.6e-13 50.8 0.0 3.1e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 GAM41784.1 - 6.2e-07 29.4 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 GAM41784.1 - 4e-06 27.0 0.0 2.3e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 GAM41784.1 - 1.5e-05 25.2 0.0 3.8e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 GAM41784.1 - 4.2e-05 23.6 0.0 8.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 PAS domain Zn-ribbon_8 PF09723.10 GAM41784.1 - 0.0094 16.1 0.1 0.019 15.1 0.1 1.4 1 0 0 1 1 1 1 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 GAM41784.1 - 0.034 13.6 0.6 0.37 10.3 0.1 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding AAA_23 PF13476.6 GAM41785.1 - 2.3e-37 129.5 4.0 2.3e-37 129.5 4.0 7.5 2 1 3 5 5 2 1 AAA domain SMC_N PF02463.19 GAM41785.1 - 9.1e-08 31.8 0.0 9.1e-08 31.8 0.0 3.6 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAM41785.1 - 2.4e-07 30.8 67.6 1.4e-05 25.0 16.8 5.4 2 2 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.6 GAM41785.1 - 4.6e-07 29.9 16.3 0.0023 17.8 0.0 4.4 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 GAM41785.1 - 8.7e-07 29.1 0.0 3.4e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 GAM41785.1 - 0.00071 19.3 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain T3SS_needle_E PF08988.10 GAM41785.1 - 0.0048 17.0 2.7 0.0048 17.0 2.7 6.0 5 1 0 6 6 6 1 Type III secretion system, cytoplasmic E component of needle AAA_16 PF13191.6 GAM41785.1 - 0.06 13.7 0.0 0.06 13.7 0.0 5.3 4 1 0 5 5 4 0 AAA ATPase domain ABC_tran PF00005.27 GAM41785.1 - 0.12 12.9 0.0 0.12 12.9 0.0 7.9 3 2 2 5 5 3 0 ABC transporter YqjK PF13997.6 GAM41785.1 - 0.14 12.4 0.4 0.83 9.9 0.4 2.5 1 0 0 1 1 1 0 YqjK-like protein AAA_13 PF13166.6 GAM41785.1 - 0.16 10.6 0.0 0.057 12.1 24.9 7.7 3 1 6 9 9 9 0 AAA domain PCI PF01399.27 GAM41786.1 - 0.0047 17.4 0.0 0.0082 16.6 0.0 1.3 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 GAM41786.1 - 0.057 13.3 0.3 0.094 12.6 0.3 1.3 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Ribosomal_60s PF00428.19 GAM41786.1 - 4.5 7.9 7.5 3.3 8.4 0.1 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein RGS PF00615.19 GAM41787.1 - 1.2e-12 48.2 0.0 2.2e-09 37.6 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Bromodomain PF00439.25 GAM41788.1 - 7.4e-24 83.6 0.7 1.6e-23 82.6 0.7 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 GAM41788.1 - 3.2e-08 33.8 0.0 6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM41788.1 - 9.2e-07 28.9 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM41788.1 - 0.00042 20.7 0.1 0.00077 19.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rad1 PF02144.16 GAM41789.1 - 6.3e-79 264.9 0.0 1.3e-47 162.2 0.0 2.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Papilin_u7 PF16626.5 GAM41790.1 - 0.19 12.3 0.3 0.5 11.0 0.1 1.8 2 1 0 2 2 2 0 Linking region between Kunitz_BPTI and I-set on papilin E1-E2_ATPase PF00122.20 GAM41791.1 - 1.8e-50 171.0 1.3 6.7e-50 169.1 1.3 2.0 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 GAM41791.1 - 2.7e-44 149.4 6.1 1.1e-11 45.0 0.2 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 GAM41791.1 - 9.6e-37 127.3 0.8 2.3e-36 126.1 0.8 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAM41791.1 - 1.5e-07 31.4 0.5 3.9e-05 23.5 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAM41791.1 - 0.029 14.8 0.2 0.092 13.1 0.2 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Transketolase_C PF02780.20 GAM41791.1 - 0.034 14.0 1.8 0.32 10.9 0.1 3.1 3 0 0 3 3 3 0 Transketolase, C-terminal domain Orai-1 PF07856.12 GAM41791.1 - 0.036 13.7 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 Mediator of CRAC channel activity EccE PF11203.8 GAM41791.1 - 0.062 13.6 0.1 31 5.0 0.1 4.4 5 0 0 5 5 5 0 Putative type VII ESX secretion system translocon, EccE PASTA PF03793.19 GAM41791.1 - 0.13 12.1 0.2 0.45 10.4 0.2 2.0 1 0 0 1 1 1 0 PASTA domain DUF3435 PF11917.8 GAM41794.1 - 1.8e-86 290.7 0.0 2.7e-86 290.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) NACHT PF05729.12 GAM41794.1 - 0.00012 22.1 0.0 0.00027 20.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 GAM41794.1 - 0.0004 19.7 0.0 0.0013 18.1 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Com_YlbF PF06133.11 GAM41794.1 - 0.014 16.0 0.0 0.092 13.4 0.0 2.3 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Glyco_hydro_16 PF00722.21 GAM41795.1 - 1.2e-06 28.2 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Methyltransf_23 PF13489.6 GAM41796.1 - 1.2e-17 64.3 0.0 1.7e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM41796.1 - 3.4e-08 34.1 0.0 8.3e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM41796.1 - 6.4e-06 26.0 0.0 7.2e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM41796.1 - 0.00013 22.6 0.0 0.00028 21.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM41796.1 - 0.00024 21.8 0.0 0.0018 19.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAM41796.1 - 0.0026 17.5 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 GAM41796.1 - 0.0035 16.8 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 GAM41796.1 - 0.034 13.6 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 GAM41796.1 - 0.049 13.2 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain LMSTEN PF07988.12 GAM41796.1 - 0.097 12.2 0.4 0.24 10.9 0.4 1.7 1 0 0 1 1 1 0 LMSTEN motif DUF3489 PF11994.8 GAM41797.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) WD40 PF00400.32 GAM41798.1 - 2.2e-49 164.4 7.6 1.5e-10 41.5 0.0 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM41798.1 - 2.3e-16 59.9 0.0 2.3e-05 24.6 0.0 5.2 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 GAM41798.1 - 1.5e-09 38.0 0.0 4.3e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAM41798.1 - 8.3e-09 36.1 0.2 2.1e-07 31.5 0.1 3.0 2 1 1 3 3 3 1 AAA ATPase domain Proteasome_A_N PF10584.9 GAM41798.1 - 2e-08 33.7 0.5 2.8 7.7 0.0 5.4 5 0 0 5 5 5 3 Proteasome subunit A N-terminal signature Ge1_WD40 PF16529.5 GAM41798.1 - 3.7e-08 32.7 1.1 0.42 9.5 0.0 5.1 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAM41798.1 - 9.9e-06 25.4 0.6 11 6.1 0.0 5.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PNP_UDP_1 PF01048.20 GAM41798.1 - 4.5e-05 22.8 0.3 0.00022 20.6 0.3 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily WXG100 PF06013.12 GAM41798.1 - 0.0063 16.7 0.4 21 5.5 0.0 4.9 5 0 0 5 5 5 0 Proteins of 100 residues with WXG APS_kinase PF01583.20 GAM41798.1 - 0.018 14.9 0.4 0.069 13.0 0.1 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase Cytochrom_D1 PF02239.16 GAM41798.1 - 0.027 13.0 0.0 1.2 7.6 0.0 2.3 1 1 0 2 2 2 0 Cytochrome D1 heme domain AAA_30 PF13604.6 GAM41798.1 - 0.057 13.1 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAM41798.1 - 0.066 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 GAM41798.1 - 0.066 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF1652 PF07865.11 GAM41798.1 - 0.12 12.3 0.0 21 5.0 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1652) AAA_22 PF13401.6 GAM41798.1 - 0.16 12.3 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain CmcI PF04989.12 GAM41798.1 - 0.2 11.4 0.1 0.38 10.4 0.1 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase adh_short PF00106.25 GAM41799.1 - 1.3e-34 119.4 0.0 2.1e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM41799.1 - 4.7e-27 95.1 0.0 9.3e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PNP_UDP_1 PF01048.20 GAM41799.1 - 1.1e-14 54.3 0.0 2.9e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Phosphorylase superfamily KR PF08659.10 GAM41799.1 - 8.2e-07 29.1 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 KR domain NB-ARC PF00931.22 GAM41799.1 - 9.2e-06 25.0 0.0 1.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF1776 PF08643.10 GAM41799.1 - 1.6e-05 24.4 0.0 0.011 15.1 0.0 2.5 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) AAA_16 PF13191.6 GAM41799.1 - 0.00027 21.3 0.1 0.00077 19.9 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain MARVEL PF01284.23 GAM41800.1 - 0.0028 17.7 3.9 0.0047 16.9 3.9 1.4 1 0 0 1 1 1 1 Membrane-associating domain PROL5-SMR PF15621.6 GAM41800.1 - 0.021 15.4 0.2 0.021 15.4 0.2 2.9 3 0 0 3 3 3 0 Proline-rich submaxillary gland androgen-regulated family Comm PF15957.5 GAM41800.1 - 0.059 13.7 0.1 0.84 10.0 0.0 2.7 3 0 0 3 3 3 0 Commissureless GAIN PF16489.5 GAM41800.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain WBP-1 PF11669.8 GAM41800.1 - 0.23 12.1 1.1 1.2 9.8 1.1 2.2 1 1 0 1 1 1 0 WW domain-binding protein 1 SUR7 PF06687.12 GAM41800.1 - 3.1 7.4 9.3 0.16 11.6 1.7 2.3 1 1 1 3 3 3 0 SUR7/PalI family FAD_binding_4 PF01565.23 GAM41801.1 - 4.9e-25 87.9 0.9 8.8e-25 87.1 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain DUF4671 PF15710.5 GAM41801.1 - 0.074 11.9 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4671) NAD_binding_1 PF00175.21 GAM41802.1 - 8.6e-06 26.4 0.0 0.25 12.0 0.0 2.6 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAM41802.1 - 0.00042 20.5 0.0 0.0064 16.6 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain EKLF_TAD2 PF16833.5 GAM41802.1 - 0.0014 18.6 0.5 0.0033 17.4 0.5 1.7 1 0 0 1 1 1 1 Erythroid krueppel-like transcription factor, transactivation 2 Metallophos PF00149.28 GAM41803.1 - 7e-17 62.6 0.3 1.1e-16 61.9 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM41803.1 - 0.00011 22.5 0.0 0.0013 18.9 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HAD PF12710.7 GAM41804.1 - 4.7e-21 76.1 0.0 6.3e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 GAM41804.1 - 0.015 14.7 0.0 3.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase Hydrolase PF00702.26 GAM41804.1 - 0.088 13.1 0.9 26 5.0 0.0 3.6 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase GCD14 PF08704.10 GAM41805.1 - 3.2e-08 33.6 0.0 0.00046 19.9 0.0 2.4 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 GAM41805.1 - 0.00099 18.9 0.2 0.003 17.4 0.1 1.9 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_25 PF13649.6 GAM41805.1 - 0.042 14.6 0.0 6.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Exo_endo_phos PF03372.23 GAM41806.1 - 1.1e-19 70.8 0.0 3.7e-19 69.2 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 GAM41806.1 - 4.4e-13 48.8 7.7 1.3e-08 34.4 1.2 2.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GAM41806.1 - 1.3e-12 47.7 1.5 1.4e-06 28.5 0.5 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM41806.1 - 0.4 11.4 1.2 1.6e+02 3.5 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat TFIIA PF03153.13 GAM41806.1 - 8.6 6.2 13.3 12 5.7 13.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_25 PF13649.6 GAM41807.1 - 2e-09 38.0 0.0 4.2e-08 33.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM41807.1 - 3.8e-06 27.4 0.0 1.1e-05 25.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM41807.1 - 0.00012 22.0 0.0 0.00042 20.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM41807.1 - 0.0089 15.4 0.0 0.037 13.4 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAM41807.1 - 0.009 15.8 0.0 0.051 13.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Complex1_LYR PF05347.15 GAM41808.1 - 2.9e-09 36.8 0.1 3.5e-09 36.6 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAM41808.1 - 6e-07 30.1 0.1 6.8e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF3638 PF12340.8 GAM41809.1 - 2.5e-92 308.3 0.0 4.1e-92 307.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 GAM41809.1 - 2.6e-15 55.5 0.1 6e-15 54.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) 4HBT_2 PF13279.6 GAM41811.1 - 2.7e-18 66.6 0.0 3.7e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 GAM41811.1 - 0.19 12.1 0.0 0.42 11.0 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily DUF1612 PF07756.12 GAM41812.1 - 8.4 6.7 10.8 2.5 8.4 2.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1612) Flavin_Reduct PF01613.18 GAM41813.1 - 7.5e-28 97.5 0.0 8.8e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Pup PF05639.11 GAM41814.1 - 0.1 13.6 1.0 0.19 12.7 1.0 1.4 1 0 0 1 1 1 0 Pup-like protein Vps5 PF09325.10 GAM41816.1 - 3.4e-89 298.4 2.2 5.7e-89 297.7 2.2 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 GAM41816.1 - 6.8e-25 87.2 0.0 1.6e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_3 PF16746.5 GAM41816.1 - 0.0087 15.8 4.7 0.32 10.7 1.1 2.5 1 1 1 2 2 2 2 BAR domain of APPL family Lipase_GDSL PF00657.22 GAM41816.1 - 0.12 12.3 0.1 0.75 9.7 0.0 2.0 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase DUF3450 PF11932.8 GAM41816.1 - 0.19 11.0 6.9 0.077 12.3 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Aldolase_II PF00596.21 GAM41817.1 - 7.8e-45 153.1 0.0 9.3e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.18 GAM41818.1 - 2.5e-170 566.2 16.9 3.1e-170 565.9 16.9 1.1 1 0 0 1 1 1 1 Calreticulin family Aldedh PF00171.22 GAM41819.1 - 1.7e-83 280.7 0.0 1.9e-83 280.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Chlam_PMP PF02415.17 GAM41819.1 - 0.15 12.6 4.8 2.4 8.8 0.0 3.1 2 1 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Dynamitin PF04912.14 GAM41821.1 - 5.1e-73 246.6 12.4 7.9e-73 246.0 12.4 1.3 1 1 0 1 1 1 1 Dynamitin Tmemb_cc2 PF10267.9 GAM41821.1 - 0.00012 21.4 3.2 0.00012 21.4 3.2 2.3 1 1 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein DUF1664 PF07889.12 GAM41821.1 - 0.0026 17.8 0.9 0.42 10.7 0.1 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) DivIC PF04977.15 GAM41821.1 - 0.0038 16.9 17.8 0.026 14.3 0.8 4.1 4 0 0 4 4 4 2 Septum formation initiator Laminin_II PF06009.12 GAM41821.1 - 0.004 17.2 0.4 0.004 17.2 0.4 3.6 3 2 1 4 4 4 1 Laminin Domain II Cep57_CLD_2 PF14197.6 GAM41821.1 - 0.023 14.8 1.0 0.023 14.8 1.0 3.8 4 1 1 5 5 4 0 Centrosome localisation domain of PPC89 KxDL PF10241.9 GAM41821.1 - 0.085 13.1 2.2 1.8 8.9 0.1 3.4 3 1 0 3 3 3 0 Uncharacterized conserved protein DUF16 PF01519.16 GAM41821.1 - 0.18 12.3 3.2 0.58 10.7 0.9 2.9 3 2 1 4 4 4 0 Protein of unknown function DUF16 PhaP_Bmeg PF09602.10 GAM41821.1 - 0.2 11.6 7.1 6.2 6.7 0.2 3.4 3 1 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Jnk-SapK_ap_N PF09744.9 GAM41821.1 - 0.26 11.5 15.6 0.097 12.9 2.4 3.4 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 GAM41821.1 - 0.3 9.9 11.3 1 8.1 3.6 3.2 3 0 0 3 3 3 0 Spc7 kinetochore protein APG6_N PF17675.1 GAM41821.1 - 0.94 10.0 14.7 6.4 7.3 4.3 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region GBP_C PF02841.14 GAM41821.1 - 1.3 8.3 7.6 0.24 10.7 1.3 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain FapA PF03961.13 GAM41821.1 - 1.6 7.3 7.3 0.74 8.3 2.1 2.3 2 1 0 2 2 2 0 Flagellar Assembly Protein A FlxA PF14282.6 GAM41821.1 - 1.6 8.8 13.2 0.58 10.2 0.2 4.4 5 0 0 5 5 4 0 FlxA-like protein TMPIT PF07851.13 GAM41821.1 - 1.7 7.8 4.1 2.4 7.3 0.5 2.5 3 0 0 3 3 3 0 TMPIT-like protein Snapin_Pallidin PF14712.6 GAM41821.1 - 2.5 8.6 9.8 1.1 9.7 0.7 4.2 4 1 0 4 4 3 0 Snapin/Pallidin Spc24 PF08286.11 GAM41821.1 - 3.4 8.0 12.7 2.7 8.3 0.4 3.7 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 Spectrin PF00435.21 GAM41821.1 - 3.6 8.1 11.6 12 6.4 1.6 3.7 3 1 0 3 3 3 0 Spectrin repeat Rho_Binding PF08912.11 GAM41821.1 - 4 8.3 11.4 0.86 10.5 0.8 3.9 4 0 0 4 4 4 0 Rho Binding ADIP PF11559.8 GAM41821.1 - 6.4 6.8 16.4 2.1 8.4 0.5 3.8 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 GAM41821.1 - 6.6 7.4 13.9 1.6 9.4 0.8 4.3 3 3 1 4 4 3 0 SlyX DUF2203 PF09969.9 GAM41821.1 - 9.4 7.0 12.1 7.4 7.3 0.7 3.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Pyr_redox_2 PF07992.14 GAM41822.1 - 7.6e-51 173.1 0.2 1e-50 172.6 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM41822.1 - 1.9e-18 66.8 0.0 8.7e-17 61.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM41822.1 - 4.8e-16 59.1 0.9 1.3e-13 51.3 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM41822.1 - 2.1e-05 23.9 0.1 5.2e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.6 GAM41822.1 - 6.6e-05 23.3 0.1 0.019 15.4 0.1 3.0 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 GAM41822.1 - 0.00067 19.8 0.5 0.24 11.7 0.1 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GAM41822.1 - 0.002 17.5 0.4 0.2 11.0 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAM41822.1 - 0.0027 16.9 0.1 0.29 10.2 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 GAM41822.1 - 0.0073 15.6 1.6 3.8 6.7 0.0 3.2 2 1 1 3 3 3 1 FAD binding domain DAO PF01266.24 GAM41822.1 - 0.0083 15.7 2.5 1.1 8.8 0.0 3.5 3 1 1 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.22 GAM41822.1 - 0.017 14.3 2.8 2.1 7.3 0.0 3.9 4 1 1 5 5 5 0 Glucose inhibited division protein A GTP_EFTU PF00009.27 GAM41822.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Shikimate_DH PF01488.20 GAM41822.1 - 0.12 12.4 0.2 9.5 6.3 0.0 2.9 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase BOFC_N PF08977.10 GAM41822.1 - 0.16 11.9 0.6 2 8.5 0.5 2.5 3 0 0 3 3 3 0 Bypass of Forespore C, N terminal FAD_binding_2 PF00890.24 GAM41822.1 - 1.2 8.1 7.2 1 8.4 0.9 2.9 3 1 0 3 3 3 0 FAD binding domain PhoD PF09423.10 GAM41823.1 - 0.00044 19.4 0.0 0.0026 16.8 0.0 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase PGA2 PF07543.12 GAM41823.1 - 0.07 13.1 2.7 0.19 11.7 2.7 1.8 1 0 0 1 1 1 0 Protein trafficking PGA2 Peptidase_S8 PF00082.22 GAM41824.1 - 1.1e-34 120.1 2.3 1.6e-34 119.6 2.3 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 GAM41824.1 - 1.3e-25 89.2 1.0 2.4e-25 88.3 1.0 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain PX PF00787.24 GAM41825.1 - 3.9e-19 68.7 0.1 7.9e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 GAM41825.1 - 5e-14 52.4 5.3 1.2e-07 31.5 1.0 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 GAM41825.1 - 0.0048 16.6 2.8 0.26 10.9 2.8 2.3 1 1 0 1 1 1 1 BAR domain Sec34 PF04136.15 GAM41825.1 - 0.034 14.0 0.4 0.063 13.2 0.1 1.6 2 0 0 2 2 2 0 Sec34-like family Occludin_ELL PF07303.13 GAM41825.1 - 0.12 13.2 1.4 2.2 9.1 0.0 2.8 3 0 0 3 3 3 0 Occludin homology domain DUF1664 PF07889.12 GAM41825.1 - 0.24 11.5 1.7 7.6 6.6 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-LITAF-like PF10601.9 GAM41826.1 - 0.0013 18.9 0.9 0.0021 18.3 0.9 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain FAD_binding_3 PF01494.19 GAM41828.1 - 1.3e-18 67.4 0.0 1.5e-16 60.6 0.0 2.9 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 GAM41828.1 - 0.0015 17.6 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 GAM41828.1 - 0.005 16.1 0.0 0.0071 15.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM41828.1 - 0.0073 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAM41828.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.6 GAM41828.1 - 0.018 14.2 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAM41828.1 - 0.023 14.9 0.1 0.058 13.6 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAM41828.1 - 0.043 12.7 0.0 0.25 10.2 0.0 2.1 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.17 GAM41828.1 - 0.19 10.9 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family tRNA-synt_His PF13393.6 GAM41829.1 - 3.4e-35 121.8 0.0 4.7e-29 101.6 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 GAM41829.1 - 6.9e-14 51.8 0.0 1.4e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAM41829.1 - 1.4e-05 25.2 0.0 2.9e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 GAM41829.1 - 0.0003 20.4 0.0 0.00058 19.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs UCH PF00443.29 GAM41830.1 - 3.9e-57 193.7 0.4 8.1e-57 192.6 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM41830.1 - 1.2e-27 97.4 2.9 2.7e-20 73.2 0.4 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 GAM41830.1 - 0.00083 18.9 2.9 0.035 13.6 2.3 2.9 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase BTB PF00651.31 GAM41832.1 - 2.8e-07 30.7 0.0 4.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Glyco_transf_22 PF03901.17 GAM41834.1 - 1.2e-46 159.8 15.7 1.7e-46 159.3 15.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Abhydrolase_6 PF12697.7 GAM41834.1 - 9.2e-11 42.8 0.0 2.1e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM41834.1 - 4.3e-09 36.0 0.3 9e-09 34.9 0.1 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAM41834.1 - 1.3e-06 28.7 0.0 2.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 GAM41834.1 - 5.3e-05 23.1 0.5 0.00073 19.3 0.5 2.4 1 1 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 GAM41834.1 - 6.9e-05 22.5 0.7 0.00046 19.8 0.2 2.6 3 0 0 3 3 3 1 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 GAM41834.1 - 0.0042 16.9 0.9 2.7 7.8 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase PEP_hydrolase PF09370.10 GAM41834.1 - 0.0046 16.2 0.5 0.73 9.0 0.0 2.2 2 0 0 2 2 2 2 Phosphoenolpyruvate hydrolase-like Abhydrolase_1 PF00561.20 GAM41834.1 - 0.0053 16.4 0.0 0.51 9.9 0.0 2.7 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM41834.1 - 0.037 13.5 0.9 2.6 7.5 0.0 2.6 2 1 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_8 PF06259.12 GAM41834.1 - 0.1 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF676 PF05057.14 GAM41834.1 - 0.11 12.1 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) CPP1-like PF11833.8 GAM41834.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.2 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Abhydrolase_5 PF12695.7 GAM41834.1 - 0.19 11.5 1.4 0.27 11.0 0.3 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family FSH1 PF03959.13 GAM41834.1 - 0.21 11.2 0.4 0.93 9.1 0.4 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) p450 PF00067.22 GAM41835.1 - 1.2e-43 149.5 0.0 1.2e-28 100.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Amino_oxidase PF01593.24 GAM41836.1 - 1.7e-82 278.1 0.1 2.5e-71 241.3 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 GAM41836.1 - 3.6e-12 46.4 0.0 7.3e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 GAM41836.1 - 2.5e-08 34.0 0.0 6.1e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 GAM41836.1 - 0.0012 19.2 2.4 0.0028 18.0 2.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box DAO PF01266.24 GAM41836.1 - 0.002 17.8 1.1 0.002 17.8 1.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM41836.1 - 0.0053 16.7 0.1 0.04 13.9 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAM41836.1 - 0.017 14.4 0.1 0.073 12.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM41836.1 - 0.056 12.7 0.2 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM41836.1 - 0.057 12.6 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family CoaE PF01121.20 GAM41837.1 - 1.5e-42 145.2 0.0 2e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase HCV_env PF01539.17 GAM41837.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 AAA_18 PF13238.6 GAM41837.1 - 0.085 13.4 0.2 0.77 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF3431 PF11913.8 GAM41838.1 - 2.7e-86 288.8 0.4 3.5e-86 288.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Lipase_3 PF01764.25 GAM41838.1 - 1.3e-12 47.8 0.1 2.4e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 GAM41838.1 - 7.9e-05 22.6 3.2 0.0016 18.4 0.1 2.9 3 0 0 3 3 3 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 GAM41838.1 - 0.023 14.0 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM41838.1 - 0.049 14.2 0.4 0.1 13.2 0.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_M16_M PF16187.5 GAM41839.1 - 5e-96 321.3 1.4 9.6e-96 320.3 1.4 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 GAM41839.1 - 3.9e-34 118.3 0.2 1e-20 74.5 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAM41839.1 - 8.6e-29 100.4 7.5 1.3e-27 96.6 2.4 3.9 2 2 1 3 3 3 1 Insulinase (Peptidase family M16) Arb2 PF09757.9 GAM41840.1 - 8.2e-105 349.6 1.5 1.1e-104 349.1 1.5 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 GAM41840.1 - 8.7e-85 284.9 0.0 1.2e-84 284.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain B-block_TFIIIC PF04182.12 GAM41840.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Gp_dh_C PF02800.20 GAM41841.1 - 8.3e-70 233.4 0.0 1.3e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAM41841.1 - 3.4e-37 126.8 1.5 7.5e-37 125.7 0.3 2.0 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GAM41841.1 - 0.029 14.5 0.1 0.11 12.6 0.1 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Pho88 PF10032.9 GAM41842.1 - 2e-76 255.3 0.0 2.5e-76 255.0 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4536 PF15055.6 GAM41842.1 - 1.4 9.2 0.0 1.4 9.2 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4536) Histone PF00125.24 GAM41843.1 - 1.1e-16 61.4 0.0 1.4e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 GAM41843.1 - 1.7e-12 46.8 0.0 3.4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 GAM41843.1 - 3.5e-05 24.0 0.0 4.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.22 GAM41845.1 - 6.4e-11 42.1 0.3 1.6e-10 40.8 0.3 1.8 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 GAM41845.1 - 2.9e-06 27.0 0.1 5.1e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAS_C PF12026.8 GAM41845.1 - 0.22 11.6 0.3 0.34 11.0 0.3 1.2 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain Sugar_tr PF00083.24 GAM41846.1 - 9.7e-37 126.9 24.3 5.9e-22 78.2 8.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM41846.1 - 2.8e-18 66.0 39.7 9.1e-10 38.0 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Polysacc_lyase PF14099.6 GAM41847.1 - 1.8e-51 175.0 10.6 2e-51 174.8 10.6 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Aldo_ket_red PF00248.21 GAM41848.1 - 2.2e-13 50.1 0.0 6.4e-13 48.6 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family COesterase PF00135.28 GAM41849.1 - 3.3e-88 296.8 0.0 4.4e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM41849.1 - 3.8e-07 30.2 0.1 4.4e-06 26.7 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM41849.1 - 0.0006 19.4 0.2 0.0011 18.5 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family MFS_1 PF07690.16 GAM41850.1 - 2.9e-25 89.0 25.6 2.1e-15 56.5 12.2 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF1563 PF07599.11 GAM41850.1 - 0.14 12.3 0.4 0.33 11.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) p450 PF00067.22 GAM41851.1 - 2.8e-58 197.8 0.0 4.1e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 GAM41851.1 - 9.6e-07 28.1 0.0 3.4e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Herpes_UL95 PF03038.14 GAM41851.1 - 0.00063 19.0 0.1 0.0011 18.2 0.1 1.3 1 0 0 1 1 1 1 UL95 family TPR_16 PF13432.6 GAM41851.1 - 0.028 15.1 0.2 0.1 13.2 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM41851.1 - 0.03 14.6 0.9 0.14 12.4 0.9 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_M19 PF01244.21 GAM41852.1 - 2.7e-104 348.8 0.0 3.4e-104 348.5 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) HSF_DNA-bind PF00447.17 GAM41853.1 - 8.6e-28 96.8 0.2 2e-27 95.6 0.2 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.8 GAM41853.1 - 0.0053 16.7 2.6 0.27 11.2 0.1 2.6 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Ets PF00178.22 GAM41853.1 - 0.012 16.0 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 Ets-domain CENP-F_leu_zip PF10473.9 GAM41853.1 - 0.021 14.8 0.9 3.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JHY PF15261.6 GAM41853.1 - 0.039 14.7 0.7 0.039 14.7 0.7 2.5 3 0 0 3 3 3 0 Jhy protein DUF2968 PF11180.8 GAM41853.1 - 0.053 13.2 3.0 0.14 11.7 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Pex19 PF04614.12 GAM41853.1 - 0.056 13.2 1.7 0.17 11.6 0.2 2.5 3 0 0 3 3 3 0 Pex19 protein family MRP-L28 PF09812.9 GAM41853.1 - 0.099 12.8 1.7 0.39 10.8 0.8 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 DUF4404 PF14357.6 GAM41853.1 - 0.14 12.8 1.1 1.4 9.6 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) APG6_N PF17675.1 GAM41853.1 - 0.57 10.7 4.0 0.45 11.0 0.8 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region MINDY_DUB PF04424.13 GAM41854.1 - 7.2e-19 67.9 0.0 1.3e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase Gcd10p PF04189.13 GAM41855.1 - 3e-120 400.9 0.1 3.8e-120 400.6 0.1 1.1 1 0 0 1 1 1 1 Gcd10p family FF PF01846.19 GAM41855.1 - 0.95 9.7 3.0 0.64 10.2 0.7 1.9 2 0 0 2 2 2 0 FF domain P21-Arc PF04062.14 GAM41856.1 - 1.1e-52 178.6 0.0 1.3e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit AAA PF00004.29 GAM41857.1 - 9.8e-17 61.6 0.0 1.8e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 GAM41857.1 - 6e-16 58.6 0.0 1.7e-15 57.2 0.0 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 GAM41857.1 - 5.4e-13 49.0 0.0 1.4e-12 47.7 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 GAM41857.1 - 4e-09 36.7 0.0 8.5e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 GAM41857.1 - 2.2e-07 30.8 0.1 6e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAM41857.1 - 2.4e-07 31.1 0.2 3e-06 27.6 0.1 2.6 2 2 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 GAM41857.1 - 1.2e-06 28.7 0.0 4.4e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 GAM41857.1 - 2.6e-06 27.4 0.2 9.3e-05 22.3 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM41857.1 - 3.7e-06 27.4 0.0 1.3e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GAM41857.1 - 6.1e-06 26.3 0.1 8e-05 22.7 0.1 2.7 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 GAM41857.1 - 6.2e-06 26.3 0.0 0.00067 19.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 GAM41857.1 - 3.1e-05 24.3 0.1 9.7e-05 22.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAM41857.1 - 3.7e-05 23.5 0.0 6.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAM41857.1 - 3.8e-05 23.5 0.0 0.00014 21.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 GAM41857.1 - 5.4e-05 23.0 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit ResIII PF04851.15 GAM41857.1 - 8.8e-05 22.6 0.0 0.047 13.7 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 GAM41857.1 - 0.00017 21.4 0.2 0.00094 19.0 0.2 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 GAM41857.1 - 0.00043 19.5 0.0 0.00078 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 GAM41857.1 - 0.0012 19.4 0.0 0.0023 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAM41857.1 - 0.0016 18.7 0.1 0.0034 17.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 GAM41857.1 - 0.0021 17.5 0.4 0.38 10.2 0.0 2.3 1 1 1 2 2 2 1 PhoH-like protein TniB PF05621.11 GAM41857.1 - 0.0025 17.2 0.0 0.025 14.0 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein DUF2075 PF09848.9 GAM41857.1 - 0.0057 15.9 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 GAM41857.1 - 0.0078 15.8 0.1 0.026 14.1 0.0 1.8 1 1 1 2 2 2 1 AAA domain DEAD PF00270.29 GAM41857.1 - 0.0085 15.9 0.1 0.071 12.9 0.1 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase TK PF00265.18 GAM41857.1 - 0.015 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase Mg_chelatase PF01078.21 GAM41857.1 - 0.017 14.5 0.2 0.12 11.7 0.1 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAM41857.1 - 0.019 14.5 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 GAM41857.1 - 0.02 14.6 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 GAM41857.1 - 0.029 14.8 0.0 0.069 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 GAM41857.1 - 0.037 14.5 0.0 0.067 13.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter T2SSE PF00437.20 GAM41857.1 - 0.043 12.9 0.0 0.1 11.7 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 GAM41857.1 - 0.067 12.9 0.0 0.65 9.7 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 GAM41857.1 - 0.068 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea F_actin_cap_B PF01115.17 GAM41857.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 F-actin capping protein, beta subunit NTPase_1 PF03266.15 GAM41857.1 - 0.12 12.3 0.1 1.3 9.0 0.1 2.2 1 1 0 2 2 2 0 NTPase His_Phos_2 PF00328.22 GAM41858.1 - 0.015 14.7 0.0 0.6 9.4 0.0 2.3 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 2) HCMV_UL124 PF17609.2 GAM41858.1 - 0.047 13.9 2.7 0.15 12.3 2.7 1.9 1 0 0 1 1 1 0 Family of unknown function Glyco_hydro_28 PF00295.17 GAM41859.1 - 1.4e-122 408.8 18.0 1.6e-122 408.6 18.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2180 PF09947.9 GAM41859.1 - 0.13 12.2 0.2 0.25 11.3 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) DUF3300 PF11737.8 GAM41860.1 - 0.87 9.1 2.9 1.8 8.0 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) Pro_isomerase PF00160.21 GAM41861.1 - 6.3e-39 133.8 0.0 1.5e-38 132.6 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CHAT PF12770.7 GAM41862.1 - 5.6e-36 124.4 0.1 9e-36 123.8 0.1 1.3 1 0 0 1 1 1 1 CHAT domain Ank_3 PF13606.6 GAM41862.1 - 1e-05 25.5 1.2 0.93 10.3 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 GAM41862.1 - 0.0025 18.4 2.0 0.27 11.8 0.0 4.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM41862.1 - 0.0037 17.8 0.1 6 7.5 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Birna_VP3 PF01767.16 GAM41862.1 - 0.035 14.2 0.2 7.1 6.7 0.1 2.5 2 0 0 2 2 2 0 Birnavirus VP3 protein DUF4267 PF14087.6 GAM41863.1 - 1.8e-24 85.9 0.1 3.7e-24 84.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Myb_DNA-binding PF00249.31 GAM41864.1 - 6.1e-14 51.9 0.0 1.5e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM41864.1 - 0.0037 17.5 0.2 0.26 11.6 0.2 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAM41864.1 - 0.0047 16.8 0.0 0.0047 16.8 0.0 2.8 3 0 0 3 3 3 1 Myb DNA-binding like MORN PF02493.20 GAM41865.1 - 1.1e-16 59.7 26.0 5.8e-06 25.9 0.6 4.6 4 0 0 4 4 4 4 MORN repeat UCH PF00443.29 GAM41865.1 - 2.8e-15 56.5 0.0 5.2e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_3 PF13920.6 GAM41865.1 - 2.4e-10 40.1 10.7 3.9e-10 39.4 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) USP7_ICP0_bdg PF12436.8 GAM41865.1 - 0.0016 17.8 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 Prok-RING_4 PF14447.6 GAM41865.1 - 0.015 15.2 10.3 0.027 14.3 10.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAM41865.1 - 0.46 10.5 11.2 0.88 9.6 11.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DS PF01916.17 GAM41866.1 - 6.1e-129 429.4 0.0 7.1e-129 429.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Acyl-CoA_dh_1 PF00441.24 GAM41867.1 - 9.6e-32 110.3 0.6 1.7e-31 109.5 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 GAM41867.1 - 6.5e-21 74.3 0.1 1.7e-20 72.9 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 GAM41867.1 - 9e-17 61.1 0.2 1.8e-16 60.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAM41867.1 - 2.1e-07 31.3 1.1 2.9e-07 30.8 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAM41867.1 - 1.7e-06 28.7 0.2 4.9e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 GAM41867.1 - 0.065 12.9 0.0 4.3 6.9 0.0 2.4 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Corona_NS2A PF05213.12 GAM41867.1 - 0.093 12.1 0.1 0.54 9.5 0.0 2.0 2 0 0 2 2 2 0 Coronavirus NS2A protein Methyltr_RsmB-F PF01189.17 GAM41869.1 - 9.6e-73 244.1 0.0 1.6e-72 243.4 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 GAM41869.1 - 4.4e-07 30.3 0.0 1.2e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 GAM41869.1 - 0.023 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Blt1 PF12754.7 GAM41870.1 - 3.6e-63 212.4 0.1 4.8e-63 212.0 0.1 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 GAM41870.1 - 4.5e-23 80.6 0.3 8.5e-23 79.7 0.3 1.5 1 0 0 1 1 1 1 Get5 carboxyl domain XPA_C PF05181.12 GAM41871.1 - 6e-26 90.2 3.1 1.3e-25 89.1 3.1 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 GAM41871.1 - 0.011 15.7 8.7 0.011 15.7 8.7 2.2 2 0 0 2 2 2 0 XPA protein N-terminal HD-ZIP_N PF04618.12 GAM41871.1 - 0.13 12.8 0.1 0.61 10.6 0.0 2.1 2 0 0 2 2 2 0 HD-ZIP protein N terminus OrfB_Zn_ribbon PF07282.11 GAM41871.1 - 2.7 8.0 7.2 2 8.4 0.1 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain NMO PF03060.15 GAM41872.1 - 1.3e-36 126.7 3.6 4e-26 92.2 0.8 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 GAM41872.1 - 1.3e-07 30.9 2.5 1.2e-06 27.8 2.5 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAM41872.1 - 1e-06 28.1 1.7 1.6e-06 27.4 1.7 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 GAM41872.1 - 0.00013 21.3 0.4 0.00028 20.2 0.4 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 GAM41872.1 - 0.23 10.6 0.5 0.4 9.8 0.5 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DAO PF01266.24 GAM41873.1 - 2.4e-48 165.5 0.0 2.9e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM41873.1 - 0.0016 18.5 0.7 0.065 13.2 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAM41873.1 - 0.013 14.7 0.2 0.26 10.5 0.2 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Invas_SpaK PF03519.14 GAM41873.1 - 0.02 15.0 0.0 2.5 8.2 0.0 3.2 3 0 0 3 3 3 0 Invasion protein B family K_oxygenase PF13434.6 GAM41873.1 - 0.022 13.9 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAM41873.1 - 0.036 13.3 0.0 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM41873.1 - 0.076 13.3 0.3 0.18 12.0 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF2271 PF10029.9 GAM41873.1 - 0.15 11.7 0.0 8.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Predicted periplasmic protein (DUF2271) HI0933_like PF03486.14 GAM41873.1 - 0.22 10.2 0.6 0.47 9.1 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein RSN1_7TM PF02714.15 GAM41874.1 - 6.8e-87 291.2 20.3 6.8e-87 291.2 20.3 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAM41874.1 - 2.5e-41 141.0 1.2 2.5e-41 141.0 1.2 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAM41874.1 - 2.2e-33 115.9 0.6 4.2e-33 115.0 0.6 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 GAM41874.1 - 1.6e-28 98.7 0.9 4e-28 97.4 0.2 2.0 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 GAM41874.1 - 0.065 13.1 0.0 0.25 11.2 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FlaF PF07309.11 GAM41874.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein FlaF Cerato-platanin PF07249.12 GAM41875.1 - 1.5e-39 134.8 0.8 2e-39 134.4 0.8 1.2 1 0 0 1 1 1 1 Cerato-platanin MelC1 PF06236.11 GAM41875.1 - 0.9 9.6 4.8 32 4.6 3.6 2.3 2 1 0 2 2 2 0 Tyrosinase co-factor MelC1 WW PF00397.26 GAM41876.1 - 4.1e-07 30.0 1.8 1.3e-06 28.3 1.8 2.0 1 0 0 1 1 1 1 WW domain Extensin_2 PF04554.13 GAM41876.1 - 0.0014 18.6 61.2 0.084 13.0 23.5 3.7 2 1 2 4 4 4 3 Extensin-like region DUF3425 PF11905.8 GAM41877.1 - 4.9e-16 58.8 0.2 1.5e-15 57.3 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) CaKB PF03185.15 GAM41878.1 - 0.076 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Acetyltransf_10 PF13673.7 GAM41879.1 - 0.0025 17.8 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM41879.1 - 0.0032 17.7 0.0 0.0042 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Chromate_transp PF02417.15 GAM41880.1 - 2.9e-28 99.0 7.0 3.3e-28 98.8 7.0 1.1 1 0 0 1 1 1 1 Chromate transporter ADH_zinc_N PF00107.26 GAM41881.1 - 1.1e-12 48.0 0.0 2.1e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM41881.1 - 3.5e-11 42.9 0.1 6.4e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAM41881.1 - 0.00037 20.4 0.0 0.00083 19.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 GAM41881.1 - 0.0018 19.3 0.0 0.0031 18.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.16 GAM41882.1 - 9.9e-41 139.8 51.3 1.4e-40 139.4 48.2 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM41882.1 - 4.5e-11 41.9 16.6 6.3e-11 41.4 16.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LapA_dom PF06305.11 GAM41882.1 - 2.7 7.9 4.5 20 5.1 1.6 3.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Zn_clus PF00172.18 GAM41883.1 - 8.4e-08 32.2 11.6 1.7e-07 31.2 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 GAM41884.1 - 1.6e-94 317.3 28.7 1.9e-94 317.1 28.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM41884.1 - 6.4e-28 97.7 37.9 9e-26 90.6 25.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CYSTM PF12734.7 GAM41884.1 - 3.4 8.1 5.6 4.3 7.7 0.3 3.0 3 0 0 3 3 3 0 Cysteine-rich TM module stress tolerance Trp_oprn_chp PF09534.10 GAM41884.1 - 7.4 6.3 8.9 18 5.1 0.8 2.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Aldo_ket_red PF00248.21 GAM41885.1 - 3.6e-71 239.7 0.0 4.2e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_7 PF13508.7 GAM41886.1 - 7.2e-07 29.5 0.0 1.4e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM41886.1 - 5.8e-06 26.5 0.0 9.9e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM41886.1 - 0.00037 20.4 0.0 0.00081 19.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM41886.1 - 0.037 14.1 0.0 4.2 7.5 0.0 2.7 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM41886.1 - 0.13 12.3 0.0 0.42 10.6 0.0 1.8 1 1 1 2 2 2 0 FR47-like protein AA_permease_2 PF13520.6 GAM41888.1 - 2e-52 178.4 48.1 2.7e-52 178.1 48.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM41888.1 - 2.8e-34 118.5 32.9 2.8e-34 118.5 32.9 1.8 2 0 0 2 2 2 1 Amino acid permease GST_N_2 PF13409.6 GAM41889.1 - 6.4e-20 71.2 0.0 1.4e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM41889.1 - 2.5e-11 43.4 0.0 1.9e-10 40.6 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM41889.1 - 0.0033 17.8 0.0 5.3 7.5 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM41889.1 - 0.0081 16.4 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM41889.1 - 0.013 15.7 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GFO_IDH_MocA PF01408.22 GAM41890.1 - 5.5e-24 85.3 0.0 9.6e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 GAM41890.1 - 0.016 15.7 0.0 0.038 14.4 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Corona_NS2A PF05213.12 GAM41890.1 - 0.069 12.5 0.1 0.22 10.8 0.0 1.7 1 1 1 2 2 2 0 Coronavirus NS2A protein RGS PF00615.19 GAM41891.1 - 8.7e-28 97.0 0.2 8.6e-27 93.8 0.1 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 GAM41891.1 - 4.4e-17 61.9 0.1 6.7e-16 58.1 0.0 2.6 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) AA_permease_2 PF13520.6 GAM41892.1 - 8.8e-64 215.9 53.9 1.1e-63 215.6 53.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM41892.1 - 9.6e-21 73.9 42.1 1.3e-20 73.5 42.1 1.0 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 GAM41892.1 - 4.1 7.4 0.0 4.1 7.4 0.0 4.5 5 0 0 5 5 5 0 LPXTG cell wall anchor motif Orf78 PF06024.12 GAM41893.1 - 0.14 12.4 1.7 0.3 11.4 1.7 1.6 1 0 0 1 1 1 0 Orf78 (ac78) FAD_binding_3 PF01494.19 GAM41894.1 - 7.6e-77 258.9 0.0 9.5e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAM41894.1 - 2.4e-46 157.8 0.0 7.2e-46 156.3 0.0 1.8 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.10 GAM41894.1 - 0.0073 15.4 0.0 0.027 13.5 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.17 GAM41894.1 - 0.015 14.6 0.1 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 GAM41894.1 - 0.047 12.8 0.6 0.094 11.8 0.6 1.4 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 GAM41894.1 - 0.048 12.5 0.0 0.1 11.4 0.0 1.6 1 0 0 1 1 1 0 MCRA family Trp_halogenase PF04820.14 GAM41894.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.24 GAM41894.1 - 0.2 11.2 0.3 0.57 9.7 0.3 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase Glyoxalase PF00903.25 GAM41895.1 - 1e-05 25.8 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sugar_tr PF00083.24 GAM41896.1 - 7.9e-27 94.2 11.1 9.1e-22 77.5 3.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM41897.1 - 4.8e-33 114.5 22.5 7.4e-33 113.9 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SnoaL_4 PF13577.6 GAM41897.1 - 2.7e-13 50.2 0.2 1.3e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 SnoaL-like domain Dioxygenase_C PF00775.21 GAM41897.1 - 1.6e-09 37.5 0.2 9.5e-09 34.9 0.1 2.1 2 0 0 2 2 2 1 Dioxygenase MFS_1 PF07690.16 GAM41898.1 - 6.7e-27 94.3 35.8 6.7e-27 94.3 35.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Peptidase_S9 PF00326.21 GAM41898.1 - 0.00018 21.1 0.3 0.0019 17.7 0.3 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 GAM41898.1 - 0.00046 19.7 0.1 0.0011 18.5 0.1 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase AXE1 PF05448.12 GAM41898.1 - 0.044 12.4 0.1 0.15 10.7 0.1 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) ATP1G1_PLM_MAT8 PF02038.16 GAM41898.1 - 1.1 8.7 0.0 1.1 8.7 0.0 3.3 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family KR PF08659.10 GAM41899.1 - 5.4e-65 218.7 0.2 5.4e-65 218.7 0.2 2.8 3 0 0 3 3 3 1 KR domain ketoacyl-synt PF00109.26 GAM41899.1 - 2.5e-53 181.2 0.0 4.7e-53 180.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAM41899.1 - 2.8e-50 171.6 0.1 5.3e-50 170.7 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 GAM41899.1 - 5.4e-50 170.3 0.0 8.3e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 GAM41899.1 - 1.1e-37 128.6 0.0 3.8e-37 126.9 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 GAM41899.1 - 6.7e-20 71.4 0.8 1.7e-18 66.8 0.1 3.1 3 0 0 3 3 3 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 GAM41899.1 - 1.8e-16 60.6 0.0 6e-16 58.9 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 GAM41899.1 - 1.9e-15 57.0 0.0 2e-14 53.7 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM41899.1 - 7.1e-15 56.2 0.0 3.9e-14 53.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 GAM41899.1 - 1.9e-11 44.0 0.0 8.7e-11 41.8 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 GAM41899.1 - 4.7e-07 30.1 1.0 1.4e-06 28.6 1.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 GAM41899.1 - 5.8e-07 29.4 0.1 1.9e-06 27.7 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.15 GAM41899.1 - 0.02 14.0 0.0 0.041 13.0 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ELFV_dehydrog PF00208.21 GAM41899.1 - 0.034 13.9 0.9 0.72 9.5 0.0 2.7 3 0 0 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Thiolase_N PF00108.23 GAM41899.1 - 0.097 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 GAM41899.1 - 0.15 11.5 0.1 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAM41899.1 - 0.17 11.3 0.3 1.5 8.2 0.1 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family FSH1 PF03959.13 GAM41900.1 - 1.2e-24 87.2 0.0 1.9e-24 86.5 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_M20 PF01546.28 GAM41901.1 - 1.1e-13 51.3 0.0 2.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 GFO_IDH_MocA PF01408.22 GAM41901.1 - 3.3e-11 44.1 0.1 7.2e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold M20_dimer PF07687.14 GAM41901.1 - 1.3e-06 28.3 0.0 3.2e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain TauD PF02668.16 GAM41902.1 - 6.4e-40 137.6 1.5 2.2e-39 135.9 1.5 1.7 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DPRP PF04244.13 GAM41902.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein DUF3830 PF12903.7 GAM41903.1 - 2.4e-25 88.9 0.0 2.9e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) DHDPS PF00701.22 GAM41904.1 - 9.2e-27 93.5 0.0 1.4e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family AA_permease PF00324.21 GAM41905.1 - 2.9e-88 296.6 24.7 3.5e-88 296.3 24.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM41905.1 - 1e-22 80.6 26.8 1.3e-22 80.2 26.8 1.1 1 0 0 1 1 1 1 Amino acid permease S_4TM PF18159.1 GAM41905.1 - 0.041 13.2 0.9 0.094 12.0 0.4 1.9 1 1 0 1 1 1 0 SMODS-associating 4TM effector domain FAD_binding_6 PF00970.24 GAM41906.1 - 2e-22 79.4 0.0 3.6e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GAM41906.1 - 6e-21 75.1 0.0 4.4e-20 72.3 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 GAM41906.1 - 5.2e-14 52.1 0.0 9.6e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Phage_TAC_6 PF09550.10 GAM41906.1 - 0.2 12.1 0.1 0.5 10.8 0.1 1.7 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC POX PF07526.11 GAM41907.1 - 0.34 11.5 4.8 0.65 10.6 4.8 1.4 1 0 0 1 1 1 0 Associated with HOX Presenilin PF01080.17 GAM41907.1 - 2.9 6.6 7.3 3.1 6.5 7.3 1.1 1 0 0 1 1 1 0 Presenilin Folliculin PF11704.8 GAM41907.1 - 5 7.0 6.5 5.6 6.8 5.8 1.4 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport p450 PF00067.22 GAM41908.1 - 1.1e-31 110.2 0.1 1.4e-31 109.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATP_bind_3 PF01171.20 GAM41908.1 - 0.16 11.7 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 PP-loop family p450 PF00067.22 GAM41909.1 - 2e-54 185.1 0.0 2.5e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1192 PF06698.11 GAM41909.1 - 2 8.5 5.7 20 5.3 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Peptidase_M19 PF01244.21 GAM41910.1 - 3.8e-103 345.0 0.0 4.6e-103 344.7 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) MFS_1 PF07690.16 GAM41911.1 - 5.5e-33 114.3 20.2 5.5e-33 114.3 20.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Ank_4 PF13637.6 GAM41912.1 - 1e-10 41.9 0.8 6.8e-07 29.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM41912.1 - 1.2e-08 35.1 2.0 3.4e-05 24.0 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM41912.1 - 2.8e-07 31.0 0.5 3.2e-06 27.6 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 GAM41912.1 - 3.6e-05 24.0 0.5 0.065 13.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 GAM41912.1 - 6e-05 23.1 0.1 0.13 12.9 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat TPR_2 PF07719.17 GAM41912.1 - 0.0026 17.7 1.8 0.29 11.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM41912.1 - 0.051 13.8 1.4 14 6.2 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF410 PF04190.13 GAM41912.1 - 0.094 12.5 0.1 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF410) TPR_1 PF00515.28 GAM41912.1 - 0.26 11.2 2.9 2.1 8.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.24 GAM41913.1 - 3.6e-28 98.6 3.1 7.6e-14 51.4 0.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM41913.1 - 9.5e-12 44.5 11.2 1e-08 34.6 0.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 GAM41913.1 - 0.16 10.2 2.4 0.22 9.7 2.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Sortilin-Vps10 PF15902.5 GAM41914.1 - 4.1e-11 42.3 8.2 0.00049 19.0 0.0 5.4 6 1 0 6 6 6 3 Sortilin, neurotensin receptor 3, CBM_1 PF00734.18 GAM41914.1 - 1.4e-10 41.0 13.1 4.9e-10 39.2 13.1 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.20 GAM41914.1 - 0.00049 19.7 40.7 2.2 8.6 0.2 9.6 9 0 0 9 9 9 6 BNR/Asp-box repeat BNR_6 PF15899.5 GAM41914.1 - 0.19 11.8 11.9 6.4 7.1 0.1 7.2 9 0 0 9 9 9 0 BNR-Asp box repeat BNR_2 PF13088.6 GAM41914.1 - 0.67 9.2 16.1 1.6 7.9 0.1 5.2 3 2 2 5 5 5 0 BNR repeat-like domain NmrA PF05368.13 GAM41915.1 - 4.4e-09 36.2 0.1 1e-08 35.1 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM41915.1 - 1.4e-08 34.9 0.0 2.2e-07 31.0 0.0 2.4 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 GAM41915.1 - 0.0023 17.9 0.0 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAM41915.1 - 0.02 14.4 0.0 0.6 9.5 0.0 2.4 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family DUF3880 PF12996.7 GAM41915.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) MFS_1 PF07690.16 GAM41916.1 - 3.7e-36 124.8 31.5 3.7e-36 124.8 31.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Esterase_phd PF10503.9 GAM41916.1 - 7.8e-12 45.2 6.0 2.6e-06 27.1 1.1 2.6 2 1 0 2 2 2 2 Esterase PHB depolymerase Zn_clus PF00172.18 GAM41916.1 - 1e-05 25.5 7.3 2.9e-05 24.1 7.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S9 PF00326.21 GAM41916.1 - 0.00033 20.2 0.4 0.00061 19.3 0.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family MASE2 PF05230.11 GAM41916.1 - 1.5 8.9 7.6 0.24 11.5 1.8 2.6 2 0 0 2 2 2 0 MASE2 domain 3HCDH_N PF02737.18 GAM41917.1 - 1.2e-23 83.9 0.0 2.6e-21 76.3 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 GAM41917.1 - 5e-23 81.5 0.0 9.4e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ApbA PF02558.16 GAM41917.1 - 8.2e-05 22.3 0.0 0.0027 17.3 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 GAM41917.1 - 0.0014 19.2 0.0 0.0038 17.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM41917.1 - 0.0072 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 GAM41917.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.8 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 GAM41917.1 - 0.12 12.6 0.1 0.46 10.8 0.0 2.0 2 1 1 3 3 3 0 TrkA-N domain NAD_binding_2 PF03446.15 GAM41917.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 GAM41917.1 - 0.16 11.3 0.1 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 GAM41918.1 - 2.2e-24 86.3 0.0 7.3e-24 84.7 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM41918.1 - 8.2e-09 35.5 0.9 0.00011 21.9 0.5 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM41918.1 - 1.3e-08 34.4 0.0 0.0006 19.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM41918.1 - 2.4e-07 29.8 0.1 5.3e-07 28.7 0.1 1.5 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 GAM41918.1 - 9.4e-07 29.3 0.1 0.00019 21.9 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM41918.1 - 2.1e-06 27.9 0.3 5.1e-06 26.6 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM41918.1 - 2e-05 23.9 0.9 3.2e-05 23.2 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 GAM41918.1 - 0.00011 21.2 1.8 0.16 10.8 0.4 2.1 1 1 0 2 2 2 2 Tryptophan halogenase SE PF08491.10 GAM41918.1 - 0.00094 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase GIDA PF01134.22 GAM41918.1 - 0.0013 17.9 0.3 0.0019 17.3 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAM41918.1 - 0.003 16.9 0.1 0.017 14.4 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAM41918.1 - 0.0059 15.9 0.2 0.22 10.8 0.1 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 GAM41918.1 - 0.013 14.9 0.2 0.018 14.4 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAM41918.1 - 0.021 14.1 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GAM41918.1 - 0.034 13.4 0.4 0.059 12.6 0.4 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 GAM41918.1 - 0.04 13.5 0.1 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 GAM41918.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 GAM41918.1 - 0.1 11.6 0.1 0.4 9.7 0.1 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein Cu-oxidase_3 PF07732.15 GAM41919.1 - 1.3e-38 131.7 0.1 1.3e-38 131.7 0.1 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAM41919.1 - 1.7e-32 112.0 6.2 4.8e-26 91.1 2.0 4.1 3 2 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 GAM41919.1 - 8.1e-27 94.3 0.1 5.4e-25 88.4 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase Methyltransf_2 PF00891.18 GAM41920.1 - 1.9e-25 89.4 0.2 4.7e-25 88.1 0.2 1.6 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 GAM41920.1 - 0.038 14.0 0.6 0.11 12.5 0.1 2.1 2 1 0 2 2 2 0 Dimerisation domain DUF4880 PF16220.5 GAM41920.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) Ank_2 PF12796.7 GAM41921.1 - 2e-89 294.3 7.6 6.1e-12 46.0 0.2 15.4 7 3 8 16 16 16 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM41921.1 - 2.8e-73 241.4 27.5 1.1e-06 29.0 0.0 24.8 13 7 13 27 27 27 15 Ankyrin repeats (many copies) Ank PF00023.30 GAM41921.1 - 5.6e-72 235.3 24.8 8.9e-06 25.9 0.0 23.3 24 0 0 24 24 24 13 Ankyrin repeat Ank_5 PF13857.6 GAM41921.1 - 1.1e-62 207.2 30.5 3.9e-08 33.4 0.0 19.0 17 3 3 20 20 20 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM41921.1 - 3.4e-59 189.8 22.6 3e-05 24.0 0.0 24.6 30 0 0 30 30 30 10 Ankyrin repeat NACHT PF05729.12 GAM41921.1 - 2.4e-08 34.1 0.1 8.2e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 GAM41921.1 - 0.0013 19.1 0.0 0.0052 17.2 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain E3_UbLigase_EDD PF11547.8 GAM41921.1 - 0.036 13.8 0.1 23 4.8 0.0 3.4 3 0 0 3 3 3 0 E3 ubiquitin ligase EDD APS_kinase PF01583.20 GAM41921.1 - 0.097 12.6 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase PS-DH PF14765.6 GAM41922.1 - 7.7e-64 215.8 0.0 1.1e-63 215.2 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 GAM41922.1 - 2.6e-63 213.2 0.2 5.9e-63 212.0 0.2 1.7 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 GAM41922.1 - 7e-62 209.3 0.0 2.3e-61 207.6 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAM41922.1 - 6.7e-52 177.0 0.0 1.3e-51 176.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM41922.1 - 2.4e-34 117.9 0.1 8e-34 116.2 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAM41922.1 - 1.4e-22 80.3 0.0 2.9e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 GAM41922.1 - 4.5e-20 72.2 0.0 3e-19 69.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM41922.1 - 9.2e-11 41.9 0.0 1.3e-09 38.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM41922.1 - 1.2e-10 41.9 0.0 3.1e-09 37.4 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM41922.1 - 1.3e-10 41.3 0.0 1.3e-09 38.1 0.0 2.6 4 0 0 4 4 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 GAM41922.1 - 1.5e-10 41.2 0.0 8.3e-10 38.7 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 GAM41922.1 - 7.3e-10 38.6 0.2 2.4e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.12 GAM41922.1 - 2.6e-07 31.2 0.0 6.1e-06 26.8 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain adh_short_C2 PF13561.6 GAM41922.1 - 1.1e-06 28.4 0.0 3.8e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 GAM41922.1 - 2.2e-06 27.9 0.1 5.9e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 GAM41922.1 - 2.4e-06 28.6 0.0 1.2e-05 26.3 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_16 PF10294.9 GAM41922.1 - 9.7e-05 22.2 0.0 0.007 16.1 0.0 2.8 2 0 0 2 2 2 1 Lysine methyltransferase 3Beta_HSD PF01073.19 GAM41922.1 - 0.001 18.1 0.1 0.0094 15.0 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 GAM41922.1 - 0.0029 17.0 1.0 0.0058 16.0 1.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 GAM41922.1 - 0.0057 16.5 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SAT PF16073.5 GAM41922.1 - 0.073 12.8 0.1 0.92 9.2 0.1 2.3 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Hydrolase_4 PF12146.8 GAM41923.1 - 9.1e-10 38.2 0.0 1.1e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM41923.1 - 7.4e-09 35.6 0.0 1.2e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM41923.1 - 7.2e-06 26.8 0.0 9.2e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 GAM41923.1 - 2e-05 23.4 0.0 0.0016 17.2 0.0 2.5 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 GAM41923.1 - 2.2e-05 24.5 0.0 5.8e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 GAM41923.1 - 0.0018 17.8 0.0 0.97 8.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Carn_acyltransf PF00755.20 GAM41924.1 - 8.5e-105 351.6 0.0 1.3e-104 351.0 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 GAM41924.1 - 7.8e-55 186.2 0.0 1.3e-36 126.5 0.0 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAM41924.1 - 3.4e-50 171.3 0.2 5.7e-50 170.6 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 GAM41924.1 - 3.4e-50 171.0 0.0 6.1e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 GAM41924.1 - 1.4e-35 121.9 0.1 3.6e-35 120.5 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAM41924.1 - 4.5e-16 59.3 0.1 3.6e-10 40.3 0.0 2.8 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 GAM41924.1 - 5.2e-12 47.0 0.0 1.8e-11 45.2 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAM41924.1 - 2.8e-09 37.1 0.0 6.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.10 GAM41924.1 - 4.9e-06 26.6 0.1 0.0065 16.4 0.0 3.1 2 1 1 3 3 3 2 KR domain PP-binding PF00550.25 GAM41924.1 - 7.7e-06 26.2 0.7 2.3e-05 24.7 0.7 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 GAM41924.1 - 0.0059 16.5 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 GAM41924.1 - 0.13 11.5 0.5 0.26 10.6 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.22 GAM41925.1 - 2.9e-45 154.9 0.0 4.5e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.23 GAM41926.1 - 7.6e-96 320.9 25.5 1.8e-54 185.2 4.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM41926.1 - 1e-68 230.1 0.0 1.3e-34 119.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAM41926.1 - 1.2e-15 57.6 0.0 3.2e-05 23.5 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAM41926.1 - 4.1e-08 33.4 3.2 0.0075 16.1 0.3 3.9 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM41926.1 - 3.4e-07 29.9 1.2 0.00034 20.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 GAM41926.1 - 1.9e-06 27.0 0.5 0.011 14.5 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 GAM41926.1 - 4.8e-06 27.1 1.6 0.031 14.7 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAM41926.1 - 9.5e-06 25.6 0.7 0.021 14.8 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase AAA_15 PF13175.6 GAM41926.1 - 1.3e-05 25.2 0.2 0.0061 16.3 0.1 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAM41926.1 - 1.7e-05 25.1 0.9 0.51 10.6 0.1 3.8 2 2 0 2 2 2 2 AAA domain PRK PF00485.18 GAM41926.1 - 6.9e-05 22.7 0.4 0.13 12.0 0.0 2.6 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 GAM41926.1 - 9.8e-05 21.7 0.7 1.7 7.9 0.0 4.2 4 0 0 4 4 4 1 Zeta toxin ATP-synt_ab PF00006.25 GAM41926.1 - 0.00011 21.9 0.2 0.08 12.6 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 GAM41926.1 - 0.00022 21.8 8.1 0.0011 19.5 0.7 2.8 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 GAM41926.1 - 0.00038 20.2 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GAM41926.1 - 0.0015 18.3 0.6 1.7 8.3 0.1 3.0 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 GAM41926.1 - 0.0024 18.4 0.1 0.15 12.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 GAM41926.1 - 0.0093 16.1 4.3 0.5 10.4 1.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain MeaB PF03308.16 GAM41926.1 - 0.0096 14.9 0.1 0.7 8.8 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 GAM41926.1 - 0.013 15.5 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 GAM41926.1 - 0.013 15.1 0.0 7.3 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAM41926.1 - 0.013 14.6 0.2 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 GAM41926.1 - 0.016 15.3 0.5 6.1 7.0 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 GAM41926.1 - 0.018 15.3 2.6 0.33 11.2 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAM41926.1 - 0.024 14.2 0.0 6.8 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 GAM41926.1 - 0.037 14.5 0.1 27 5.2 0.0 3.8 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 GAM41926.1 - 0.042 13.0 0.2 8.8 5.4 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.6 GAM41926.1 - 0.082 13.1 0.3 17 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 GAM41926.1 - 0.085 12.8 0.1 4.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.6 GAM41926.1 - 2.2 8.6 9.8 15 5.9 0.2 4.3 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Glyco_hydro_11 PF00457.17 GAM41927.1 - 1e-60 204.4 18.1 1.2e-60 204.2 18.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Maff2 PF12750.7 GAM41927.1 - 0.093 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Maff2 family Pyr_redox_3 PF13738.6 GAM41928.1 - 1.6e-17 63.7 0.1 2e-14 53.6 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM41928.1 - 2.1e-14 53.4 0.0 2.6e-12 46.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAM41928.1 - 7.7e-13 47.7 0.7 1.7e-09 36.7 0.2 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAM41928.1 - 9.9e-10 38.1 0.2 2.2e-07 30.4 0.1 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAM41928.1 - 1.2e-06 28.7 0.0 3.1e-05 24.1 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAM41928.1 - 0.00057 18.7 0.1 0.0025 16.6 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 GAM41928.1 - 0.0013 19.2 0.3 0.44 11.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SnoaL_2 PF12680.7 GAM41928.1 - 0.0017 18.9 0.0 0.0059 17.2 0.0 1.9 1 0 0 1 1 1 1 SnoaL-like domain FAD_binding_3 PF01494.19 GAM41928.1 - 0.0021 17.4 0.0 0.0048 16.2 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAM41928.1 - 0.0021 17.4 0.0 0.036 13.3 0.0 2.6 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.24 GAM41928.1 - 0.0034 16.5 0.0 0.0064 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 GAM41928.1 - 0.034 13.5 0.1 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4176 PF13780.6 GAM41928.1 - 0.051 13.6 0.2 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) Shikimate_DH PF01488.20 GAM41928.1 - 0.059 13.4 0.0 7 6.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 GAM41928.1 - 0.063 12.3 0.5 0.42 9.7 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 GAM41928.1 - 0.084 13.1 0.2 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 GAM41928.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sugar_tr PF00083.24 GAM41930.1 - 1.5e-96 324.0 24.7 1.8e-96 323.7 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM41930.1 - 2.2e-27 95.9 17.3 2.2e-27 95.9 17.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.12 GAM41931.1 - 2.6e-29 101.3 2.6 5.8e-29 100.2 2.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM41931.1 - 3.9e-20 72.2 0.1 6.3e-20 71.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM41931.1 - 6.5e-07 30.5 0.0 1.4e-06 29.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAM41931.1 - 2e-05 24.2 0.3 3.4e-05 23.4 0.3 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 GAM41931.1 - 0.00018 20.9 0.3 0.0003 20.2 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Asp_decarbox PF02261.16 GAM41931.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Aspartate decarboxylase TrkA_N PF02254.18 GAM41931.1 - 0.034 14.4 0.1 0.061 13.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain SUR7 PF06687.12 GAM41932.1 - 5.3e-12 45.8 2.9 6.4e-12 45.5 2.9 1.0 1 0 0 1 1 1 1 SUR7/PalI family SQHop_cyclase_N PF13249.6 GAM41933.1 - 4.1e-62 209.9 1.2 2.7e-58 197.4 0.2 3.2 3 0 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 GAM41933.1 - 2.9e-48 164.6 0.1 1.7e-46 158.8 0.2 2.6 2 1 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 GAM41933.1 - 0.00052 19.7 7.5 0.0012 18.6 0.2 4.3 5 0 0 5 5 5 1 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 GAM41933.1 - 0.00056 19.0 0.0 0.59 9.1 0.0 2.7 2 1 0 2 2 2 2 A-macroglobulin TED domain Pec_lyase PF09492.10 GAM41933.1 - 0.013 14.8 0.0 0.57 9.4 0.0 2.2 2 0 0 2 2 2 0 Pectic acid lyase Amidohydro_2 PF04909.14 GAM41934.1 - 9e-36 124.1 0.0 1.1e-35 123.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Peptidase_S15 PF02129.18 GAM41935.1 - 3.1e-42 145.0 0.2 7.9e-39 133.9 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 GAM41935.1 - 4.2e-31 108.7 0.0 5.8e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Sugar_tr PF00083.24 GAM41936.1 - 1.8e-69 234.8 24.8 2e-69 234.6 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM41936.1 - 1.6e-21 76.6 23.4 1.6e-21 76.6 23.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.25 GAM41938.1 - 3e-16 59.5 0.0 7.4e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.18 GAM41938.1 - 2.1e-12 46.6 2.4 5.1e-12 45.4 0.1 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain NAD_binding_8 PF13450.6 GAM41938.1 - 2.6e-09 37.2 0.0 1.5e-07 31.5 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 GAM41938.1 - 1.9e-08 33.2 0.1 5.5e-08 31.7 0.0 1.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like adh_short_C2 PF13561.6 GAM41938.1 - 1.9e-08 34.1 0.0 4.4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase K_oxygenase PF13434.6 GAM41938.1 - 3.1e-07 29.9 0.3 8.1e-05 21.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAM41938.1 - 9.3e-07 28.4 0.1 0.029 13.6 0.1 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.10 GAM41938.1 - 2.1e-05 24.5 0.0 0.0016 18.3 0.0 2.6 2 0 0 2 2 2 1 KR domain Zn_clus PF00172.18 GAM41938.1 - 6e-05 23.1 1.5 0.00013 22.0 1.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 GAM41938.1 - 0.00022 20.5 0.0 0.042 13.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 GAM41938.1 - 0.00091 19.3 0.0 2.2 8.3 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 GAM41938.1 - 0.002 17.5 0.2 0.079 12.3 0.0 2.6 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_9 PF13454.6 GAM41938.1 - 0.0042 17.1 0.0 0.087 12.8 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 GAM41938.1 - 0.0081 15.8 0.2 0.06 12.9 0.2 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase GDP_Man_Dehyd PF16363.5 GAM41938.1 - 0.039 13.4 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 GAM41938.1 - 0.056 13.9 0.2 34 4.9 0.0 3.4 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 GAM41938.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Thi4 PF01946.17 GAM41938.1 - 0.19 10.9 0.3 4.9 6.3 0.1 2.3 2 0 0 2 2 2 0 Thi4 family Aldo_ket_red PF00248.21 GAM41939.1 - 6.1e-76 255.4 0.0 6.8e-76 255.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Thiolase_N PF00108.23 GAM41940.1 - 7.1e-65 218.9 0.0 1.3e-64 218.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAM41940.1 - 1.6e-40 137.5 0.2 7.8e-40 135.3 0.1 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 GAM41940.1 - 0.00021 21.0 0.0 0.052 13.4 0.0 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 GAM41940.1 - 0.00079 19.1 0.7 0.0075 15.9 0.7 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain DUF2236 PF09995.9 GAM41941.1 - 0.00068 19.9 0.6 0.00093 19.5 0.6 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) MFS_1 PF07690.16 GAM41942.1 - 1.6e-35 122.7 42.0 5.8e-35 120.9 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MWFE PF15879.5 GAM41942.1 - 0.075 13.2 0.0 0.49 10.6 0.0 2.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit MFS_1 PF07690.16 GAM41943.1 - 6.7e-35 120.6 32.3 6.7e-35 120.6 32.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_A24 PF01478.18 GAM41943.1 - 0.15 12.5 0.2 0.15 12.5 0.2 3.2 2 2 0 2 2 2 0 Type IV leader peptidase family DUF2070 PF09843.9 GAM41943.1 - 3.7 5.7 22.9 0.075 11.3 10.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) AnmK PF03702.14 GAM41944.1 - 3.1e-55 187.8 0.0 1.2e-34 120.0 0.0 2.1 2 0 0 2 2 2 2 Anhydro-N-acetylmuramic acid kinase FGGY_C PF02782.16 GAM41944.1 - 0.027 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain UL42 PF17638.2 GAM41945.1 - 0.72 9.8 3.0 3.9 7.5 0.1 2.3 2 0 0 2 2 2 0 HCMV UL42 Methyltransf_2 PF00891.18 GAM41946.1 - 1.8e-22 79.7 0.0 2.7e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 GAM41946.1 - 0.00054 20.6 0.0 0.0037 17.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MarR_2 PF12802.7 GAM41946.1 - 0.049 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 MarR family Ubie_methyltran PF01209.18 GAM41946.1 - 0.05 12.9 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PTR2 PF00854.21 GAM41947.1 - 1.1e-55 189.1 3.5 2.6e-55 187.9 3.5 1.5 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 GAM41947.1 - 1.5e-08 33.9 29.2 1.7e-08 33.8 24.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAM41947.1 - 9.5e-06 24.7 0.6 0.0018 17.2 0.7 2.7 1 1 1 2 2 2 2 MFS_1 like family EBP PF05241.12 GAM41947.1 - 3.3 7.1 9.9 0.81 9.1 4.6 2.3 2 0 0 2 2 2 0 Emopamil binding protein GDP_Man_Dehyd PF16363.5 GAM41948.1 - 1.3e-120 402.8 0.0 1.6e-120 402.5 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAM41948.1 - 2.3e-56 191.0 0.0 2.9e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM41948.1 - 7.1e-05 22.1 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAM41948.1 - 0.024 13.7 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 GAM41948.1 - 0.17 11.5 0.0 0.48 9.9 0.0 1.7 3 0 0 3 3 3 0 NmrA-like family HgmA PF04209.13 GAM41949.1 - 2.1e-131 438.5 0.1 2.7e-131 438.2 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase MFS_1 PF07690.16 GAM41950.1 - 5.9e-35 120.8 28.2 5.9e-35 120.8 28.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM41950.1 - 5.2e-08 31.8 2.1 5.2e-08 31.8 2.1 1.7 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DUF1918 PF08940.11 GAM41950.1 - 0.0017 17.9 0.1 0.0031 17.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1918) IPTL-CTERM PF18203.1 GAM41950.1 - 0.64 10.0 3.9 2.4 8.2 1.7 2.6 2 0 0 2 2 2 0 IPTL-CTERM motif FAD_binding_3 PF01494.19 GAM41951.1 - 7.3e-34 117.5 0.0 6e-33 114.5 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 GAM41951.1 - 2.9e-07 30.0 0.1 0.0016 17.8 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM41951.1 - 2.3e-06 27.0 0.1 0.00042 19.7 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 GAM41951.1 - 0.00012 21.2 0.0 0.0041 16.2 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 GAM41951.1 - 0.00022 20.9 0.1 0.012 15.3 0.5 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM41951.1 - 0.00043 19.1 0.0 0.012 14.3 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 GAM41951.1 - 0.00053 19.0 0.2 0.017 14.0 0.1 2.7 2 1 0 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.12 GAM41951.1 - 0.00078 18.6 0.0 0.21 10.6 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAM41951.1 - 0.0049 16.0 0.1 0.01 15.0 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 GAM41951.1 - 0.0055 16.0 0.0 0.18 11.1 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM41951.1 - 0.0061 16.8 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAM41951.1 - 0.014 14.5 0.2 0.019 14.0 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 GAM41951.1 - 0.017 15.6 0.1 11 6.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM41951.1 - 0.021 14.8 0.1 0.63 10.0 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 GAM41951.1 - 0.071 12.4 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 GAM41951.1 - 0.078 12.2 0.2 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 Thi4 family DUF3712 PF12505.8 GAM41952.1 - 2.6e-22 79.4 1.6 2.6e-22 79.4 1.6 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF3712) Amidohydro_1 PF01979.20 GAM41953.1 - 3.1e-23 82.7 0.3 7.6e-23 81.4 0.3 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM41953.1 - 1.7e-12 47.6 0.1 2.6e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family PepX_C PF08530.10 GAM41954.1 - 1.3e-25 90.7 0.1 2.6e-25 89.7 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 GAM41954.1 - 2.6e-22 79.7 0.3 4e-22 79.1 0.3 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) MFS_1 PF07690.16 GAM41954.1 - 5.6e-19 68.3 10.8 9.7e-19 67.5 10.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM41954.1 - 3.6e-08 32.8 0.5 7.8e-08 31.7 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 GAM41954.1 - 0.044 12.7 0.1 0.044 12.7 0.1 2.4 3 0 0 3 3 3 0 Sugar (and other) transporter Abhydrolase_1 PF00561.20 GAM41955.1 - 4.5e-24 85.5 0.0 6e-23 81.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM41955.1 - 2.2e-17 63.1 0.1 1.5e-16 60.4 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM41955.1 - 1.4e-13 51.9 0.0 1.9e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 GAM41955.1 - 1.1e-08 34.2 0.0 6e-06 25.2 0.0 2.0 2 0 0 2 2 2 2 Ndr family DUF915 PF06028.11 GAM41955.1 - 7.8e-07 28.7 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.13 GAM41955.1 - 9.4e-06 25.6 0.0 0.029 14.2 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase Abhydrolase_4 PF08386.10 GAM41955.1 - 6e-05 23.1 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein BAAT_C PF08840.11 GAM41955.1 - 7.1e-05 22.8 0.0 0.00025 21.0 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.7 GAM41955.1 - 0.00013 21.8 0.0 0.4 10.4 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAM41955.1 - 0.0024 17.4 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.20 GAM41955.1 - 0.0068 16.5 0.1 0.011 15.8 0.1 1.3 1 1 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.8 GAM41955.1 - 0.0074 15.9 0.0 0.025 14.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Palm_thioest PF02089.15 GAM41955.1 - 0.011 15.7 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase FSH1 PF03959.13 GAM41955.1 - 0.012 15.3 0.0 0.14 11.8 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 GAM41955.1 - 0.046 13.6 0.0 0.096 12.5 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 GAM41955.1 - 0.049 13.3 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 GAM41955.1 - 0.089 12.7 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) DUF1057 PF06342.12 GAM41955.1 - 0.093 11.7 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) PAF-AH_p_II PF03403.13 GAM41955.1 - 0.094 11.2 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II MoaF_C PF17409.2 GAM41956.1 - 1e-48 163.7 0.2 3.6e-48 161.9 0.1 1.8 2 0 0 2 2 2 1 MoaF C-terminal domain MoaF PF10703.9 GAM41956.1 - 2.5e-32 111.0 0.1 1.7e-27 95.5 0.0 2.1 2 0 0 2 2 2 2 MoaF N-terminal domain PA_decarbox PF05870.11 GAM41956.1 - 0.0021 17.7 0.1 0.0056 16.3 0.0 1.6 2 0 0 2 2 2 1 Phenolic acid decarboxylase (PAD) v110 PF01639.17 GAM41956.1 - 0.073 12.9 0.0 18 5.3 0.0 2.4 2 0 0 2 2 2 0 Viral family 110 AA_permease_2 PF13520.6 GAM41957.1 - 1.1e-29 103.5 38.3 1.3e-24 86.8 25.1 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 GAM41957.1 - 0.00027 19.7 23.4 0.00027 19.7 23.4 2.1 1 1 1 2 2 2 1 Amino acid permease Zn_clus PF00172.18 GAM41958.1 - 7.6e-07 29.2 11.7 1.8e-06 27.9 11.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDZ_2 PF13180.6 GAM41958.1 - 0.0094 16.3 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain FAD_binding_3 PF01494.19 GAM41959.1 - 1.1e-07 31.4 2.9 2.3e-06 27.1 2.9 2.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM41959.1 - 1.6e-07 30.9 0.1 2.4e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM41959.1 - 2.7e-07 30.7 0.9 8.4e-07 29.1 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ADC PF06314.11 GAM41959.1 - 5.9e-07 29.3 0.0 9.5e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) DAO PF01266.24 GAM41959.1 - 7.8e-06 25.7 0.5 1.7e-05 24.5 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM41959.1 - 1.1e-05 24.7 0.7 1.9e-05 23.9 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 GAM41959.1 - 2.8e-05 23.2 0.2 0.00011 21.2 0.0 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 GAM41959.1 - 0.001 19.6 0.0 0.0026 18.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAM41959.1 - 0.0012 18.2 0.2 0.0022 17.4 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 GAM41959.1 - 0.0027 16.9 0.2 0.0038 16.4 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 GAM41959.1 - 0.005 15.6 0.2 0.0071 15.1 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 GAM41959.1 - 0.027 13.7 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 GAM41959.1 - 0.028 13.7 0.1 0.043 13.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAM41959.1 - 0.049 12.9 0.2 0.09 12.1 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 GAM41959.1 - 0.06 13.0 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.24 GAM41959.1 - 0.14 11.4 0.1 0.27 10.5 0.1 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Methyltransf_3 PF01596.17 GAM41960.1 - 3.4e-13 49.2 0.0 4.4e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 GAM41960.1 - 4.1e-11 43.8 0.0 6.4e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 GAM41961.1 - 2.6e-27 95.7 48.4 5e-22 78.3 35.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_CA PF00484.19 GAM41961.1 - 0.11 12.8 0.1 0.25 11.6 0.1 1.6 1 1 0 1 1 1 0 Carbonic anhydrase ketoacyl-synt PF00109.26 GAM41962.1 - 2.6e-72 243.4 0.0 5.7e-72 242.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 GAM41962.1 - 2e-69 234.0 0.0 6.5e-69 232.3 0.0 2.0 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 GAM41962.1 - 3.1e-40 138.6 0.0 5e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM41962.1 - 4.6e-33 113.7 0.7 1.3e-32 112.3 0.7 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 GAM41962.1 - 3.6e-28 99.2 0.0 1.9e-27 96.9 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 GAM41962.1 - 9.4e-17 61.2 0.0 1.8e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 GAM41962.1 - 2.7e-08 34.2 0.0 9.1e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 GAM41962.1 - 1.6e-07 31.6 0.0 4.3e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 GAM41962.1 - 0.00027 21.6 0.3 0.29 11.7 0.0 3.5 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 GAM41962.1 - 0.00095 18.6 0.0 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain VCBS PF13517.6 GAM41963.1 - 3.6e-13 49.9 18.9 7.5e-08 32.8 2.0 4.1 1 1 4 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 GAM41963.1 - 4.6e-10 39.1 2.4 0.0059 16.0 0.1 3.5 1 1 2 3 3 3 3 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 GAM41963.1 - 1.1e-07 31.8 6.9 0.0066 16.6 0.2 3.7 3 0 0 3 3 3 2 FG-GAP repeat EF-hand_1 PF00036.32 GAM41963.1 - 3.6e-06 26.1 2.6 0.64 9.7 0.2 3.8 4 0 0 4 4 3 2 EF hand DUF3642 PF12182.8 GAM41963.1 - 0.00011 22.3 4.2 0.67 10.3 0.1 3.6 3 1 0 3 3 3 2 Bacterial lipoprotein DUF1905 PF08922.11 GAM41963.1 - 0.0003 20.8 0.5 5.9 7.0 0.0 4.1 1 1 3 4 4 4 1 Domain of unknown function (DUF1905) PliI PF16743.5 GAM41963.1 - 0.00071 19.3 2.4 0.71 9.6 0.1 3.0 2 1 1 3 3 3 2 Periplasmic lysozyme inhibitor of I-type lysozyme EF-hand_6 PF13405.6 GAM41963.1 - 0.00079 19.2 2.8 2.6 8.2 0.1 4.0 4 0 0 4 4 3 2 EF-hand domain CBM_6 PF03422.15 GAM41963.1 - 0.0052 17.1 11.1 1.9 8.8 0.2 4.7 2 1 3 5 5 5 2 Carbohydrate binding module (family 6) RicinB_lectin_2 PF14200.6 GAM41963.1 - 0.0054 17.4 7.5 0.033 14.9 2.1 2.8 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like EF-hand_4 PF12763.7 GAM41963.1 - 0.028 14.4 2.8 2.5 8.1 0.1 3.4 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 GAM41963.1 - 0.033 13.7 7.3 0.86 9.2 0.4 3.1 3 0 0 3 3 3 0 EF hand MYT1 PF08474.11 GAM41963.1 - 0.042 13.8 0.0 6.2 6.7 0.0 2.8 1 1 3 4 4 4 0 Myelin transcription factor 1 EF-hand_7 PF13499.6 GAM41963.1 - 0.095 13.2 1.0 54 4.3 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain pair DUF4304 PF14137.6 GAM41963.1 - 0.15 12.2 0.4 5.8 7.1 0.0 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF4304) FaeA PF04703.12 GAM41963.1 - 0.83 10.1 8.3 10 6.6 0.1 4.3 5 0 0 5 5 4 0 FaeA-like protein Crystall_2 PF09076.10 GAM41963.1 - 6.4 6.8 7.0 5 7.1 0.2 3.6 2 1 2 4 4 4 0 Beta/Gamma crystallin F-box-like_2 PF13013.6 GAM41964.1 - 0.16 11.9 0.0 0.46 10.5 0.0 1.9 1 1 0 1 1 1 0 F-box-like domain KR PF08659.10 GAM41965.1 - 7.3e-50 169.4 0.2 1.2e-49 168.6 0.2 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 GAM41965.1 - 4e-10 39.5 0.1 1.2e-09 38.0 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM41965.1 - 9.7e-07 28.6 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase VCBS PF13517.6 GAM41966.1 - 4.5e-29 100.8 56.5 4.9e-09 36.6 6.5 7.9 4 2 4 8 8 8 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Vps62 PF06101.11 GAM41966.1 - 3.2e-10 38.9 6.2 1.7e-09 36.5 3.4 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 TcdB_toxin_midN PF12256.8 GAM41966.1 - 9.2e-10 38.2 3.1 2.6 7.4 0.0 6.3 5 1 1 6 6 6 3 Insecticide toxin TcdB middle/N-terminal region Ank_2 PF12796.7 GAM41966.1 - 8.6e-09 35.9 0.0 0.0036 17.9 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM41966.1 - 6.4e-06 26.1 0.0 0.25 12.0 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 GAM41966.1 - 8.7e-06 26.2 0.0 0.13 12.9 0.0 4.2 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Dockerin_1 PF00404.18 GAM41966.1 - 1.3e-05 25.3 7.3 3.3 8.0 0.2 5.4 5 0 0 5 5 5 2 Dockerin type I domain Ank PF00023.30 GAM41966.1 - 9.8e-05 22.6 0.1 0.021 15.2 0.0 3.9 2 1 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 GAM41966.1 - 0.00021 21.5 0.0 0.0076 16.5 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) FG-GAP PF01839.23 GAM41966.1 - 0.0046 17.1 34.0 0.014 15.5 1.3 6.7 6 1 0 6 6 6 3 FG-GAP repeat MFS_1 PF07690.16 GAM41968.1 - 1.5e-33 116.2 35.9 1.2e-32 113.3 28.2 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM41968.1 - 8.2e-13 48.0 11.2 1.2e-11 44.2 5.0 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 GAM41968.1 - 5.1e-05 21.9 2.6 0.00011 20.8 2.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.18 GAM41968.1 - 0.00017 21.6 3.1 0.00017 21.6 3.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_2 PF02230.16 GAM41969.1 - 3.6e-22 79.2 0.0 2.7e-21 76.4 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 GAM41969.1 - 6.7e-05 22.5 0.0 0.00024 20.7 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 GAM41969.1 - 0.015 15.2 0.0 2.5 7.9 0.0 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold Sugar_tr PF00083.24 GAM41970.1 - 4.2e-48 164.3 11.8 1.8e-29 103.0 3.1 2.9 1 1 1 2 2 2 2 Sugar (and other) transporter Glyco_hydro_45 PF02015.16 GAM41970.1 - 0.077 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 Glyco_hydro_3 PF00933.21 GAM41971.1 - 1.3e-27 97.1 0.0 2.1e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM41971.1 - 1.4e-18 66.7 0.3 2.8e-18 65.8 0.0 1.7 2 0 0 2 2 2 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 GAM41971.1 - 8.1e-16 58.6 0.0 2.1e-15 57.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain DUF4976 PF16347.5 GAM41971.1 - 2.3e-08 34.2 3.3 2.3e-07 31.0 3.3 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) CARDB PF07705.11 GAM41971.1 - 0.00062 20.0 0.1 0.0014 18.8 0.1 1.6 1 0 0 1 1 1 1 CARDB DUF11 PF01345.18 GAM41971.1 - 0.02 15.2 2.1 0.24 11.7 2.1 2.4 1 1 0 1 1 1 0 Domain of unknown function DUF11 polyprenyl_synt PF00348.17 GAM41972.1 - 1.9e-51 174.6 0.0 4.1e-51 173.5 0.0 1.5 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 GAM41972.1 - 8.1e-07 28.6 0.3 0.00063 19.2 0.3 2.3 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain CRAL_TRIO PF00650.20 GAM41973.1 - 2.2e-25 89.2 0.0 3.2e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAM41973.1 - 0.0071 16.5 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MFS_1 PF07690.16 GAM41974.1 - 3.2e-32 111.8 39.3 3.2e-32 111.8 39.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM41975.1 - 8.3e-13 48.0 0.6 1.7e-12 47.0 0.5 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain TPP_enzyme_N PF02776.18 GAM41976.1 - 5.2e-38 130.3 0.1 1.6e-37 128.8 0.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAM41976.1 - 6.1e-18 65.1 0.0 1.6e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAM41976.1 - 4.3e-10 39.4 0.0 2e-09 37.3 0.0 2.2 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Glyco_hydro_15 PF00723.21 GAM41977.1 - 3.1e-104 349.3 0.1 3.6e-104 349.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 DUF3682 PF12446.8 GAM41977.1 - 2 8.9 18.1 6.2 7.3 18.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Recep_L_domain PF01030.24 GAM41978.1 - 0.00048 20.2 0.6 0.21 11.7 0.2 3.8 2 2 1 3 3 3 2 Receptor L domain Sugar_tr PF00083.24 GAM41979.1 - 1.4e-125 419.7 17.5 1.7e-125 419.5 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM41979.1 - 1.7e-23 83.1 22.0 1.7e-23 83.1 22.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM41980.1 - 1.5e-70 238.3 24.5 1.8e-70 238.1 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM41980.1 - 2.4e-16 59.6 29.5 2.4e-16 59.6 29.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM41980.1 - 1.7e-05 23.5 2.1 1.7e-05 23.5 2.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4383 PF14325.6 GAM41980.1 - 0.12 12.6 7.2 0.56 10.5 7.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) Spc29 PF17082.5 GAM41981.1 - 0.00027 20.9 1.8 0.00032 20.6 1.8 1.3 1 0 0 1 1 1 1 Spindle Pole Component 29 Apolipoprotein PF01442.18 GAM41981.1 - 0.0019 18.1 3.9 0.01 15.7 3.9 2.0 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Spc7 PF08317.11 GAM41981.1 - 0.003 16.5 8.1 0.003 16.5 8.1 1.6 1 1 1 2 2 2 1 Spc7 kinetochore protein Laminin_I PF06008.14 GAM41981.1 - 0.0068 16.1 1.9 0.0068 16.1 1.9 1.7 1 1 0 2 2 2 1 Laminin Domain I Tweety PF04906.13 GAM41981.1 - 0.017 13.8 0.1 0.025 13.3 0.1 1.2 1 0 0 1 1 1 0 Tweety Cluap1 PF10234.9 GAM41981.1 - 0.027 13.9 5.5 0.036 13.4 5.5 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 WDCP PF15390.6 GAM41981.1 - 0.036 12.5 3.5 0.044 12.2 3.5 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family AAA_23 PF13476.6 GAM41981.1 - 0.073 13.6 6.1 0.1 13.1 6.1 1.3 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.6 GAM41981.1 - 0.076 13.5 3.7 0.15 12.6 0.4 2.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Exonuc_VII_L PF02601.15 GAM41981.1 - 0.18 11.4 4.2 0.2 11.2 4.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DHR10 PF18595.1 GAM41981.1 - 0.28 11.2 15.7 0.1 12.7 10.3 2.2 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain FmiP_Thoc5 PF09766.9 GAM41981.1 - 0.29 10.4 8.7 0.32 10.2 8.0 1.3 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 SlyX PF04102.12 GAM41981.1 - 0.37 11.5 5.6 0.47 11.1 1.7 2.5 2 0 0 2 2 2 0 SlyX ALMT PF11744.8 GAM41981.1 - 0.38 9.5 2.6 0.46 9.3 1.9 1.2 1 1 0 1 1 1 0 Aluminium activated malate transporter DUF3053 PF11254.8 GAM41981.1 - 0.53 9.8 2.8 0.62 9.6 1.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) KLRAQ PF10205.9 GAM41981.1 - 0.81 10.0 9.4 0.2 11.9 3.5 2.3 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF1664 PF07889.12 GAM41981.1 - 1.4 9.0 5.2 1.7 8.7 3.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 GAM41981.1 - 1.4 9.5 14.6 0.056 14.0 7.4 2.0 2 1 0 2 2 2 0 Apg6 coiled-coil region PEARLI-4 PF05278.12 GAM41981.1 - 1.8 8.1 11.1 0.11 12.0 5.8 1.6 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) CC2-LZ PF16516.5 GAM41981.1 - 1.9 8.9 11.4 2.9 8.3 7.1 2.4 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator UPF0242 PF06785.11 GAM41981.1 - 1.9 8.5 11.6 1.2 9.2 7.2 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4164 PF13747.6 GAM41981.1 - 2.1 8.7 9.6 2.9 8.2 2.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) OmpH PF03938.14 GAM41981.1 - 2.3 8.5 13.2 32 4.8 12.7 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Ly49 PF08391.10 GAM41981.1 - 2.8 8.3 5.1 0.97 9.8 2.4 1.6 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF16 PF01519.16 GAM41981.1 - 3.1 8.3 9.0 2.7 8.5 3.5 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 TMPIT PF07851.13 GAM41981.1 - 3.5 6.8 7.0 3.4 6.8 6.5 1.4 1 1 0 1 1 1 0 TMPIT-like protein XhlA PF10779.9 GAM41981.1 - 3.9 7.7 10.4 0.51 10.6 5.4 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Spc24 PF08286.11 GAM41981.1 - 4.4 7.6 8.3 2.3 8.5 4.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3450 PF11932.8 GAM41981.1 - 4.5 6.5 10.4 0.88 8.8 5.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 GAM41981.1 - 4.8 7.3 12.6 2.1 8.4 1.1 3.0 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Tex_N PF09371.10 GAM41981.1 - 6.2 6.5 11.1 3 7.5 3.8 2.7 2 1 1 3 3 3 0 Tex-like protein N-terminal domain EMP24_GP25L PF01105.24 GAM41981.1 - 7.1 6.5 7.3 15 5.5 7.3 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD FAM76 PF16046.5 GAM41981.1 - 7.5 5.8 10.2 8.2 5.7 0.1 2.0 1 1 1 2 2 2 0 FAM76 protein MFS_1 PF07690.16 GAM41982.1 - 2.6e-36 125.3 20.0 7.1e-36 123.9 20.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Ferric_reduct PF01794.19 GAM41982.1 - 0.052 13.7 3.5 0.078 13.1 2.2 2.1 1 1 0 1 1 1 0 Ferric reductase like transmembrane component Bac_luciferase PF00296.20 GAM41983.1 - 3.1e-57 194.4 0.0 4e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 GAM41984.1 - 7.9e-22 77.6 45.2 1.4e-21 76.9 45.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.25 GAM41984.1 - 0.0027 17.2 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.16 GAM41985.1 - 9.3e-25 87.3 35.0 9.3e-25 87.3 35.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Aa_trans PF01490.18 GAM41986.1 - 4e-24 85.1 38.3 4.8e-24 84.8 38.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FAD_binding_3 PF01494.19 GAM41987.1 - 1.6e-08 34.2 1.5 1.1e-07 31.4 1.5 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM41987.1 - 4.5e-05 23.6 0.4 0.00017 21.8 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM41987.1 - 0.00027 20.3 0.1 0.00079 18.7 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM41987.1 - 0.00046 19.9 5.1 0.00059 19.5 1.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM41987.1 - 0.00089 18.1 0.4 0.018 13.7 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 GAM41987.1 - 0.0012 18.9 0.3 0.0065 16.5 0.3 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAM41987.1 - 0.0052 15.9 0.1 0.017 14.1 0.1 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 GAM41987.1 - 0.027 13.3 0.8 0.08 11.8 0.4 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 GAM41987.1 - 0.054 14.1 0.4 0.12 12.9 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM41987.1 - 0.088 12.1 0.4 0.16 11.2 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CHAT PF12770.7 GAM41988.1 - 1.6e-31 109.8 0.0 2.9e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_7 PF13176.6 GAM41988.1 - 0.18 11.9 6.0 7.9 6.8 0.1 5.4 4 1 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 GAM41988.1 - 1.8 8.7 7.0 18 5.5 0.0 5.2 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 GAM41988.1 - 3.2 8.2 5.7 10 6.6 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM41988.1 - 7.5 6.6 35.2 0.073 13.0 1.0 9.4 11 1 1 12 12 12 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 GAM41989.1 - 1.2e-44 152.6 3.6 4.9e-37 127.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM41989.1 - 1.8e-39 135.2 1.0 5.3e-39 133.7 1.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 GAM41989.1 - 0.02 14.2 0.3 0.043 13.1 0.1 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 GAM41989.1 - 0.026 14.4 0.5 0.038 13.9 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 GAM41989.1 - 0.064 13.1 0.1 0.097 12.6 0.1 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus AdoHcyase_NAD PF00670.21 GAM41989.1 - 0.067 13.3 0.3 0.17 11.9 0.3 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fungal_trans_2 PF11951.8 GAM41990.1 - 6.6e-10 38.4 0.0 1.4e-09 37.3 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pox_A_type_inc PF04508.12 GAM41990.1 - 0.15 11.9 1.7 0.31 11.0 1.7 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF899 PF05988.12 GAM41991.1 - 4.6e-76 255.1 0.0 5.5e-76 254.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.21 GAM41991.1 - 0.00086 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAM41991.1 - 0.005 16.6 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin MCRA PF06100.11 GAM41992.1 - 1.7e-101 340.5 0.0 9.2e-90 301.8 0.0 2.0 1 1 1 2 2 2 2 MCRA family FAD_binding_4 PF01565.23 GAM41993.1 - 7.8e-20 71.0 0.0 1.2e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF2278 PF10042.9 GAM41994.1 - 4.8e-76 255.3 0.1 7.4e-76 254.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) LTD PF00932.19 GAM41994.1 - 0.00051 20.4 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 Lamin Tail Domain Stirrup PF09061.6 GAM41994.1 - 0.011 15.9 0.0 0.03 14.5 0.0 1.7 1 0 0 1 1 1 0 Stirrup PLA2_B PF01735.18 GAM41995.1 - 8.4e-186 618.1 8.1 9.8e-186 617.9 8.1 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Ifi-6-16 PF06140.13 GAM41997.1 - 1.2e-08 34.8 8.5 2.1e-08 34.0 8.5 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family p450 PF00067.22 GAM41998.1 - 3.2e-49 168.0 0.0 4.3e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 GAM41998.1 - 4.9e-07 29.7 0.0 9.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM41998.1 - 0.0007 20.3 0.0 0.0056 17.4 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM41998.1 - 0.00086 19.1 0.0 0.0043 16.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM41998.1 - 0.084 13.6 0.0 0.27 12.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Cauli_AT PF03233.13 GAM41998.1 - 0.092 12.7 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Aphid transmission protein Aldedh PF00171.22 GAM41999.1 - 3.8e-79 266.3 0.0 4.7e-79 266.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAM41999.1 - 0.085 12.3 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Y_phosphatase3 PF13350.6 GAM42000.1 - 8.9e-52 176.4 0.0 8.1e-51 173.2 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAM42000.1 - 0.0066 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 GAM42000.1 - 0.019 14.5 0.0 0.045 13.3 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family RapA_C PF12137.8 GAM42000.1 - 0.077 12.0 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal DUF2492 PF10678.9 GAM42000.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2492) polyprenyl_synt PF00348.17 GAM42001.1 - 1.2e-64 217.9 0.0 2.8e-64 216.6 0.0 1.7 2 0 0 2 2 2 1 Polyprenyl synthetase Prenyltrans PF00432.21 GAM42001.1 - 0.00047 19.8 0.0 0.016 14.9 0.0 3.1 3 0 0 3 3 3 1 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 GAM42001.1 - 0.03 13.4 0.0 0.089 11.9 0.0 1.8 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain DUF2959 PF11172.8 GAM42001.1 - 0.049 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Med26 PF08711.11 GAM42001.1 - 0.067 13.2 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 TFIIS helical bundle-like domain p450 PF00067.22 GAM42002.1 - 8.9e-73 245.6 0.0 1.1e-72 245.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 GAM42003.1 - 9e-72 242.3 0.0 1.2e-71 241.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 GAM42004.1 - 9.1e-36 123.1 0.1 1.3e-35 122.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42004.1 - 4.1e-25 88.7 0.0 6.1e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM42004.1 - 2.4e-11 43.9 0.5 5.5e-07 29.7 0.0 2.1 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 GAM42004.1 - 0.0002 20.9 0.1 0.0004 19.9 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1120 PF06551.12 GAM42004.1 - 0.094 12.9 0.0 0.64 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1120) Glyco_hydro_cc PF11790.8 GAM42006.1 - 3.1e-57 193.9 4.3 3.6e-57 193.7 4.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Pox_A14 PF05767.12 GAM42007.1 - 0.00011 22.3 0.4 0.00032 20.8 0.4 1.7 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 HlyIII PF03006.20 GAM42007.1 - 0.00093 19.0 1.5 0.002 17.9 0.3 2.0 1 1 1 2 2 2 1 Haemolysin-III related OATP PF03137.20 GAM42007.1 - 0.095 11.0 0.6 2 6.6 0.1 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_Dp1 PF16938.5 GAM42007.1 - 0.18 12.0 8.0 0.088 13.0 4.4 2.4 2 0 0 2 2 2 0 Putative phage holin Dp-1 FliG_N PF14842.6 GAM42007.1 - 0.2 12.2 0.0 0.33 11.5 0.0 1.3 1 0 0 1 1 1 0 FliG N-terminal domain DUF4131 PF13567.6 GAM42007.1 - 2.1 7.9 8.4 1.9 8.1 2.0 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) Glyco_hydro_18 PF00704.28 GAM42009.1 - 4e-23 82.6 1.4 2.2e-22 80.2 1.4 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4646 PF15496.6 GAM42010.1 - 0.0002 22.0 0.0 0.00035 21.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.9 GAM42010.1 - 0.0047 17.0 0.0 0.0083 16.2 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF2637 PF10935.8 GAM42010.1 - 0.11 12.3 2.2 0.083 12.8 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) DUF3112 PF11309.8 GAM42012.1 - 1.2e-16 60.8 10.0 1e-09 38.2 0.4 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) Peptidase_S10 PF00450.22 GAM42013.1 - 7.5e-78 262.8 0.2 9.9e-78 262.4 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_31 PF01055.26 GAM42014.1 - 1.3e-146 489.3 6.1 1.9e-146 488.7 6.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 GAM42014.1 - 6.1e-37 126.4 0.4 1.1e-36 125.5 0.4 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 GAM42014.1 - 6.5e-12 45.6 0.3 3e-11 43.5 0.3 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like Stig1 PF04885.13 GAM42015.1 - 0.06 13.8 1.2 0.21 12.1 0.1 2.0 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 DSPn PF14671.6 GAM42016.1 - 1.5e-42 145.4 0.0 5e-40 137.2 0.0 2.5 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 GAM42016.1 - 5.4e-16 58.6 0.1 1.4e-15 57.2 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM42016.1 - 1.9e-06 27.6 0.0 3.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 GAM42016.1 - 0.082 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Pcc1 PF09341.10 GAM42017.1 - 3.9e-31 107.0 0.4 4.9e-31 106.7 0.4 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 Abhydrolase_1 PF00561.20 GAM42018.1 - 2.2e-28 99.6 0.2 3.1e-28 99.1 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM42018.1 - 1.5e-25 89.8 0.2 4.8e-17 62.0 0.2 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM42018.1 - 4.9e-19 69.8 0.0 6.2e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAM42018.1 - 9.7e-07 28.5 0.6 0.026 14.0 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family DUF1749 PF08538.10 GAM42018.1 - 0.0011 18.1 0.2 0.003 16.7 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Chlorophyllase2 PF12740.7 GAM42018.1 - 0.0014 17.6 0.0 0.0033 16.4 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S15 PF02129.18 GAM42018.1 - 0.0014 18.2 0.0 0.37 10.3 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 GAM42018.1 - 0.0015 18.4 0.0 0.0044 16.8 0.0 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 GAM42018.1 - 0.02 14.4 0.0 0.093 12.3 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Ser_hydrolase PF06821.13 GAM42018.1 - 0.026 14.4 0.0 0.24 11.2 0.0 2.2 2 1 0 2 2 2 0 Serine hydrolase PAF-AH_p_II PF03403.13 GAM42018.1 - 0.034 12.6 0.1 3.1 6.2 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase PF07224.11 GAM42018.1 - 0.04 12.9 0.1 0.1 11.6 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase Abhydrolase_5 PF12695.7 GAM42018.1 - 0.04 13.7 0.1 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF915 PF06028.11 GAM42018.1 - 0.052 12.9 0.1 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) AXE1 PF05448.12 GAM42018.1 - 0.059 12.0 0.0 0.2 10.3 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) RTA1 PF04479.13 GAM42019.1 - 2.2e-45 154.8 6.1 2.5e-31 108.9 2.8 2.1 2 0 0 2 2 2 2 RTA1 like protein Phage_holin_3_6 PF07332.11 GAM42019.1 - 3.8 7.6 7.4 1 9.5 0.1 2.6 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III EPV_E5 PF08135.11 GAM42019.1 - 8.2 6.9 12.7 0.24 11.8 6.2 1.8 2 0 0 2 2 2 0 Major transforming protein E5 family Fungal_trans_2 PF11951.8 GAM42020.1 - 7.7e-10 38.1 1.3 1.1e-09 37.6 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM42020.1 - 1.8e-07 31.1 9.8 2.7e-07 30.6 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GSHPx PF00255.19 GAM42021.1 - 1.6e-39 133.8 0.0 2.4e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 GAM42021.1 - 0.0021 18.0 0.0 0.0034 17.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Translin PF01997.16 GAM42022.1 - 3.9e-46 157.6 0.3 4.9e-46 157.3 0.3 1.2 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.22 GAM42022.1 - 0.078 13.0 0.0 0.65 10.1 0.0 2.2 2 0 0 2 2 2 0 GMP synthase C terminal domain ABC_tran PF00005.27 GAM42023.1 - 9.3e-44 149.3 0.0 5.2e-25 88.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAM42023.1 - 2.2e-29 102.9 37.3 2.1e-28 99.7 9.9 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 GAM42023.1 - 1.3e-10 41.1 1.5 0.14 11.5 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAM42023.1 - 5.5e-08 32.9 1.0 0.006 16.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 GAM42023.1 - 3e-06 27.3 5.1 0.18 11.5 0.0 4.2 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAM42023.1 - 2.8e-05 24.4 0.0 0.38 11.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 GAM42023.1 - 9.4e-05 22.1 2.2 0.28 11.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 GAM42023.1 - 0.00051 19.6 0.9 0.11 12.0 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region cobW PF02492.19 GAM42023.1 - 0.00079 19.1 2.7 0.4 10.3 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 GAM42023.1 - 0.0013 18.5 0.7 8.2 6.1 0.0 4.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_16 PF13191.6 GAM42023.1 - 0.0048 17.3 0.2 0.94 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 GAM42023.1 - 0.0052 17.0 1.0 2 8.7 0.3 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit T2SSE PF00437.20 GAM42023.1 - 0.0055 15.8 0.5 0.92 8.5 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 GAM42023.1 - 0.0095 16.4 0.0 2.4 8.6 0.0 3.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 GAM42023.1 - 0.0099 16.1 0.6 0.69 10.1 0.0 3.1 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 GAM42023.1 - 0.016 15.2 0.7 4.3 7.2 0.1 2.6 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.9 GAM42023.1 - 0.02 13.9 0.8 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 GAM42023.1 - 0.026 14.6 0.7 3.8 7.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 GAM42023.1 - 0.029 14.9 0.2 3.9 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 GAM42023.1 - 0.033 13.5 0.2 2 7.6 0.0 2.3 2 0 0 2 2 2 0 Septin Pox_A32 PF04665.12 GAM42023.1 - 0.037 13.5 0.6 0.21 11.0 0.1 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.6 GAM42023.1 - 0.038 14.1 0.1 9 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 GAM42023.1 - 0.062 13.2 2.0 0.55 10.1 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 GAM42023.1 - 0.067 12.8 0.4 3 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAM42023.1 - 0.071 12.4 0.9 2.5 7.3 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin UFD1 PF03152.14 GAM42023.1 - 0.096 12.2 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 AAA_24 PF13479.6 GAM42023.1 - 0.099 12.3 1.3 0.46 10.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 GAM42023.1 - 0.11 12.1 1.8 10 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 GAM42023.1 - 0.14 12.2 0.4 6.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 GAM42023.1 - 0.14 12.2 5.5 0.83 9.7 0.7 2.5 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 GAM42023.1 - 0.15 11.4 1.9 7.3 5.9 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.6 GAM42023.1 - 0.25 11.7 0.8 33 4.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain DEAD PF00270.29 GAM42023.1 - 0.27 11.0 1.9 7.6 6.3 0.0 3.3 4 0 0 4 4 4 0 DEAD/DEAH box helicase HSP70 PF00012.20 GAM42025.1 - 2e-07 29.6 0.0 9.1e-07 27.4 0.0 1.8 2 0 0 2 2 2 1 Hsp70 protein BcrAD_BadFG PF01869.20 GAM42025.1 - 0.00085 18.9 0.0 0.0073 15.8 0.0 2.2 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family MreB_Mbl PF06723.13 GAM42025.1 - 0.091 11.6 0.1 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Ribonucleas_3_3 PF14622.6 GAM42026.1 - 1.6e-10 41.3 0.0 2.3e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 GAM42026.1 - 3.1e-09 37.4 0.1 2.4e-08 34.5 0.1 2.1 1 1 0 1 1 1 1 Ribonuclease III domain Pro-kuma_activ PF09286.11 GAM42027.1 - 1e-47 162.0 0.0 3.2e-47 160.4 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain WD40 PF00400.32 GAM42027.1 - 4.8e-05 24.1 0.2 0.75 10.8 0.0 3.4 2 1 1 3 3 3 2 WD domain, G-beta repeat Peptidase_S8 PF00082.22 GAM42027.1 - 0.00024 20.4 0.5 0.00047 19.5 0.5 1.4 1 0 0 1 1 1 1 Subtilase family SecD-TM1 PF13721.6 GAM42027.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 SecD export protein N-terminal TM region Ribosomal_L22e PF01776.17 GAM42028.1 - 1.6e-47 160.4 0.2 1.9e-47 160.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family BTK PF00779.19 GAM42029.1 - 2.4 8.1 5.9 0.47 10.3 1.3 2.1 2 0 0 2 2 2 0 BTK motif DUF676 PF05057.14 GAM42030.1 - 1.7e-49 168.3 0.0 2.6e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 GAM42030.1 - 3.8e-06 27.7 0.0 5.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 GAM42030.1 - 1.7e-05 24.8 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 GAM42030.1 - 0.0049 16.6 0.1 0.012 15.4 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 GAM42030.1 - 0.0061 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Lipase_2 PF01674.18 GAM42030.1 - 0.012 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) Hydrolase_6 PF13344.6 GAM42031.1 - 1e-22 80.1 0.0 2e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM42031.1 - 1.1e-12 47.8 0.0 9.7e-12 44.8 0.0 2.6 2 1 0 2 2 2 1 HAD-hyrolase-like Lipase_3 PF01764.25 GAM42031.1 - 0.025 14.4 0.0 0.089 12.7 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) Hydrolase PF00702.26 GAM42031.1 - 0.058 13.7 0.0 5.1 7.3 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase CFEM PF05730.11 GAM42032.1 - 0.0013 18.8 9.8 0.0028 17.7 9.8 1.5 1 0 0 1 1 1 1 CFEM domain ATP-synt_C PF00137.21 GAM42035.1 - 3.2e-35 120.3 34.6 1.3e-21 76.7 15.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF1713 PF08213.11 GAM42036.1 - 1.2e-10 41.2 19.5 2e-10 40.4 19.5 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 GAM42036.1 - 0.11 13.2 0.2 0.35 11.6 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial protein Pet20 G-alpha PF00503.20 GAM42037.1 - 3.8e-108 361.8 0.3 4.6e-108 361.5 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM42037.1 - 2.6e-12 46.5 0.2 1.3e-07 31.2 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM42037.1 - 4.7e-08 32.7 0.3 0.00012 21.6 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GAM42037.1 - 0.012 15.8 0.5 1.3 9.3 0.1 2.9 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 GAM42037.1 - 0.019 14.4 0.1 0.037 13.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein MMR_HSR1 PF01926.23 GAM42037.1 - 0.042 13.9 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 GAM42037.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 GAM42037.1 - 0.063 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sugar_tr PF00083.24 GAM42038.1 - 4.2e-118 395.1 25.9 5.2e-118 394.8 25.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1445 PF07286.12 GAM42038.1 - 2.6e-46 157.1 0.0 4.4e-46 156.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) MFS_1 PF07690.16 GAM42038.1 - 1.1e-25 90.3 50.6 5.7e-22 78.1 27.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 GAM42039.1 - 1.5e-48 165.6 31.5 1.5e-48 165.6 31.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42039.1 - 4.8e-11 42.2 8.7 4.8e-11 42.2 8.7 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 GAM42039.1 - 1.6 6.9 10.0 0.19 10.0 4.3 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3425 PF11905.8 GAM42040.1 - 1.7e-24 86.2 0.6 2.9e-24 85.4 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 GAM42040.1 - 0.0042 17.1 12.7 0.1 12.7 6.0 2.4 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 GAM42040.1 - 0.014 15.4 20.0 0.13 12.4 5.9 2.4 2 0 0 2 2 2 0 Basic region leucine zipper ZapB PF06005.12 GAM42040.1 - 0.037 14.5 1.9 0.037 14.5 1.9 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DUF572 PF04502.13 GAM42040.1 - 0.095 12.3 5.1 0.13 11.8 5.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PRKG1_interact PF15898.5 GAM42040.1 - 0.66 10.9 9.1 1.5 9.8 9.1 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 GAM42040.1 - 2.7 8.7 5.7 0.3 11.8 1.0 1.8 2 0 0 2 2 2 0 Initiation control protein YabA Hydrophobin PF01185.18 GAM42041.1 - 1.9e-11 44.4 12.9 2.7e-11 43.9 12.9 1.2 1 0 0 1 1 1 1 Fungal hydrophobin CAP_N PF01213.19 GAM42041.1 - 9.7 5.6 6.0 14 5.0 6.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GMC_oxred_N PF00732.19 GAM42042.1 - 1.1e-65 222.0 0.0 1.7e-65 221.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM42042.1 - 2.1e-29 102.9 0.1 3.6e-29 102.2 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAM42042.1 - 8e-08 31.7 0.1 7.3e-07 28.6 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAM42042.1 - 9.5e-06 24.9 0.3 0.00089 18.4 0.3 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM42042.1 - 2.1e-05 24.3 2.1 0.0034 17.0 0.2 2.8 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM42042.1 - 9.2e-05 22.6 0.4 0.00032 20.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM42042.1 - 0.0004 19.7 0.1 0.0057 15.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM42042.1 - 0.13 11.5 0.5 0.49 9.6 0.1 1.9 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 GAM42042.1 - 0.13 12.5 0.4 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 GAM42042.1 - 0.18 11.0 0.1 8.4 5.5 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2282 PF10048.9 GAM42043.1 - 0.36 10.9 4.2 33 4.6 0.1 3.4 2 1 1 3 3 3 0 Predicted integral membrane protein (DUF2282) Bys1 PF04681.12 GAM42044.1 - 8.4e-15 55.0 1.1 9.9e-15 54.8 1.1 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein AMP-binding PF00501.28 GAM42045.1 - 8.5e-78 261.8 0.0 2.8e-77 260.1 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 GAM42045.1 - 5.5e-57 192.9 0.0 1.3e-56 191.6 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein AMP-binding_C PF13193.6 GAM42045.1 - 4e-13 50.1 0.0 1.1e-12 48.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 GAM42045.1 - 3.4e-11 43.3 0.0 6.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 GAM42045.1 - 1.4e-09 37.7 0.0 2.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM42045.1 - 1.3e-07 30.9 0.0 2.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAM42045.1 - 0.0014 17.8 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAM42045.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FAD_binding_4 PF01565.23 GAM42046.1 - 9.3e-29 99.9 4.3 1.6e-28 99.2 4.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM42046.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like GMC_oxred_N PF00732.19 GAM42047.1 - 5e-52 177.1 0.0 8.4e-52 176.4 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM42047.1 - 1.7e-33 116.2 0.0 3.3e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAM42047.1 - 1.9e-06 27.2 0.0 2.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 GAM42047.1 - 8.2e-05 22.0 0.2 0.0002 20.7 0.1 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 GAM42047.1 - 0.00011 22.3 0.9 0.00058 20.0 0.1 2.5 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM42047.1 - 0.0011 18.6 0.5 0.0043 16.7 0.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM42047.1 - 0.0017 17.7 0.2 0.0053 16.0 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM42047.1 - 0.0028 16.8 0.0 0.0077 15.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 GAM42047.1 - 0.0068 15.7 0.1 0.065 12.5 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM42047.1 - 0.058 12.1 0.2 0.14 10.8 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 GAM42047.1 - 0.066 13.5 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain OPT PF03169.15 GAM42048.1 - 1.3e-129 433.7 47.1 1.5e-129 433.4 47.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_hyd_65N_2 PF14498.6 GAM42049.1 - 3.2e-49 167.9 0.0 4.8e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Bac_rhamnosid6H PF17389.2 GAM42049.1 - 0.01 15.1 0.3 0.019 14.2 0.3 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Rap1_C PF11626.8 GAM42049.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Glyco_hydro_35 PF01301.19 GAM42050.1 - 2e-77 260.9 2.2 2.7e-77 260.5 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 GAM42050.1 - 7.3e-07 28.9 1.6 1.4e-06 27.9 1.6 1.5 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 GAM42050.1 - 8e-06 26.4 5.4 0.0055 17.3 0.2 3.8 4 1 0 4 4 4 2 Beta-galactosidase jelly roll domain Aldo_ket_red PF00248.21 GAM42051.1 - 1.3e-69 234.6 0.0 1.5e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family APH PF01636.23 GAM42052.1 - 4.3e-08 33.4 0.0 6.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RS4NT PF08071.12 GAM42052.1 - 0.094 12.9 0.0 4.6 7.4 0.0 2.5 2 0 0 2 2 2 0 RS4NT (NUC023) domain RIO1 PF01163.22 GAM42052.1 - 0.098 12.2 0.0 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.20 GAM42052.1 - 0.14 11.5 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 GAM42052.1 - 0.17 11.5 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ECH_1 PF00378.20 GAM42053.1 - 2.9e-41 141.5 0.0 3.8e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM42053.1 - 1.8e-28 100.0 0.1 3.5e-27 95.8 0.0 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase NTS_2 PF15448.6 GAM42053.1 - 0.072 13.5 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein Saf_2TM PF18303.1 GAM42053.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain COG5 PF10392.9 GAM42054.1 - 0.018 15.2 0.1 0.053 13.7 0.1 1.8 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Hydant_A_N PF05378.13 GAM42054.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region COesterase PF00135.28 GAM42057.1 - 2.5e-74 251.0 0.0 3e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM42057.1 - 1.1e-05 25.4 0.1 0.15 11.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold TauD PF02668.16 GAM42058.1 - 1.9e-40 139.4 0.2 3.7e-40 138.4 0.2 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3533 PF12051.8 GAM42059.1 - 1.5e-111 373.0 18.8 1.9e-111 372.7 18.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF1746 PF08508.10 GAM42059.1 - 0.043 14.1 1.5 0.27 11.6 2.0 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1746) Con-6 PF10346.9 GAM42060.1 - 7.4e-26 89.9 6.1 1.2e-13 50.9 0.2 2.2 2 0 0 2 2 2 2 Conidiation protein 6 RTP1_C2 PF10304.9 GAM42060.1 - 0.024 14.3 0.6 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 NmrA PF05368.13 GAM42062.1 - 1.3e-09 38.0 0.0 2.2e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM42062.1 - 2.4e-09 37.3 0.0 3.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 GAM42063.1 - 3.6e-40 137.2 0.0 5.4e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAM42063.1 - 1.7e-10 40.7 0.0 2.1e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAM42063.1 - 1.1e-07 32.2 0.0 2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 GAM42063.1 - 4.3e-06 27.2 0.0 9.4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_C PF03720.15 GAM42063.1 - 0.0028 18.1 0.0 0.047 14.1 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain MFS_1 PF07690.16 GAM42064.1 - 3.1e-36 125.0 34.2 4e-36 124.7 34.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M20 PF01546.28 GAM42064.1 - 2.3e-33 115.7 0.0 3.5e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Sugar_tr PF00083.24 GAM42064.1 - 6.6e-12 45.0 6.8 6.6e-12 45.0 6.8 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter Peptidase_M28 PF04389.17 GAM42064.1 - 0.00048 19.9 0.0 0.0019 17.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.14 GAM42064.1 - 0.0016 18.3 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DLH PF01738.18 GAM42065.1 - 3.6e-32 111.7 0.0 4.2e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF915 PF06028.11 GAM42065.1 - 0.021 14.1 0.0 0.061 12.7 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.21 GAM42065.1 - 0.064 12.7 0.0 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family GAS2 PF02187.17 GAM42065.1 - 0.17 12.0 0.2 0.68 10.1 0.1 2.0 1 1 1 2 2 2 0 Growth-Arrest-Specific Protein 2 Domain NMT1 PF09084.11 GAM42066.1 - 8.6e-05 22.6 0.0 0.00027 20.9 0.0 1.8 2 0 0 2 2 2 1 NMT1/THI5 like SBP_bac_3 PF00497.20 GAM42066.1 - 0.061 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 GAM42066.1 - 0.065 12.9 0.0 0.4 10.3 0.0 2.4 1 1 0 1 1 1 0 NMT1-like family Phosphonate-bd PF12974.7 GAM42066.1 - 0.099 12.2 0.0 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein MFS_1 PF07690.16 GAM42067.1 - 1.2e-28 100.1 54.5 3.4e-18 65.7 16.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42067.1 - 1.3e-09 37.5 45.8 7.9e-07 28.3 13.7 3.6 2 2 1 3 3 3 3 Sugar (and other) transporter Sugar_tr PF00083.24 GAM42068.1 - 8e-116 387.6 29.4 2.5e-115 385.9 29.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM42068.1 - 1.1e-20 73.9 44.2 9.6e-15 54.3 23.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ThiJ_like PF17124.5 GAM42069.1 - 8.4e-14 51.7 0.0 1.2e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 GAM42069.1 - 5.6e-13 49.0 0.0 6.4e-12 45.6 0.0 2.4 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 GAM42069.1 - 0.0035 17.0 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Pkinase PF00069.25 GAM42070.1 - 7e-25 87.9 0.0 5.4e-24 85.0 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM42070.1 - 4.5e-10 39.2 0.0 2.6e-09 36.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM42070.1 - 0.017 14.5 0.0 0.042 13.1 0.0 1.6 2 0 0 2 2 2 0 Kinase-like YonK PF09642.10 GAM42070.1 - 0.18 12.0 0.0 0.51 10.5 0.0 1.7 1 0 0 1 1 1 0 YonK protein Insulin_TMD PF17870.1 GAM42071.1 - 0.035 14.2 0.5 2.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF4448 PF14610.6 GAM42071.1 - 0.14 11.9 0.2 0.21 11.4 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) AA_permease_2 PF13520.6 GAM42072.1 - 1.6e-27 96.4 9.9 2.1e-27 96.0 9.9 1.1 1 0 0 1 1 1 1 Amino acid permease Ank_2 PF12796.7 GAM42072.1 - 2.8e-24 85.5 0.6 1.7e-07 31.7 0.3 4.7 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM42072.1 - 1.3e-22 79.8 3.6 9.1e-06 26.1 0.1 6.7 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAM42072.1 - 4.4e-17 61.7 6.0 0.0078 16.6 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 GAM42072.1 - 2.7e-14 51.9 8.8 0.25 12.0 0.0 8.9 7 2 2 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 GAM42072.1 - 7.1e-13 48.5 6.8 0.095 13.0 0.0 7.0 3 2 5 8 8 8 6 Ankyrin repeats (many copies) AA_permease PF00324.21 GAM42072.1 - 1e-07 30.9 8.9 1.5e-07 30.4 8.9 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 GAM42072.1 - 0.00027 19.7 4.9 0.00039 19.3 4.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MIP PF00230.20 GAM42073.1 - 2.3e-45 155.1 14.6 3.2e-45 154.6 14.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein PfkB PF00294.24 GAM42074.1 - 1.3e-46 159.3 0.7 1.7e-46 158.9 0.7 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 GAM42074.1 - 8e-05 22.1 0.1 0.00011 21.6 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Glyco_hydro_76 PF03663.14 GAM42076.1 - 5.5e-162 539.4 21.4 6.4e-162 539.2 21.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 GAM42076.1 - 0.081 12.0 12.5 0.29 10.2 1.8 3.1 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 Abhydrolase_1 PF00561.20 GAM42077.1 - 1.3e-19 70.9 0.1 5.1e-15 55.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 GAM42077.1 - 6.2e-18 64.8 0.1 2.1e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein DUF2264 PF10022.9 GAM42078.1 - 2.9e-135 450.9 0.0 3.7e-135 450.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) VSP PF03302.13 GAM42080.1 - 8e-06 25.0 8.6 1.1e-05 24.5 8.6 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.10 GAM42080.1 - 4.4e-05 22.8 1.8 4.4e-05 22.8 1.8 1.9 2 0 0 2 2 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 GAM42080.1 - 7.2e-05 22.6 0.1 9.4e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Podoplanin PF05808.11 GAM42080.1 - 0.00012 22.2 6.6 0.00012 22.2 6.6 1.6 2 0 0 2 2 2 1 Podoplanin Amnionless PF14828.6 GAM42080.1 - 0.0023 16.9 0.1 0.0029 16.5 0.1 1.2 1 0 0 1 1 1 1 Amnionless MGC-24 PF05283.11 GAM42080.1 - 0.0028 18.1 8.8 0.0028 18.1 8.8 1.8 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin PTP_tm PF18861.1 GAM42080.1 - 0.031 14.3 3.5 0.051 13.6 3.5 1.5 1 1 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Stevor PF17410.2 GAM42080.1 - 0.14 11.7 1.8 0.2 11.2 1.8 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Hamartin PF04388.12 GAM42080.1 - 0.15 10.7 6.6 0.24 10.0 6.6 1.3 1 0 0 1 1 1 0 Hamartin protein RIFIN PF02009.16 GAM42080.1 - 0.17 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Rifin AJAP1_PANP_C PF15298.6 GAM42080.1 - 0.19 11.9 13.5 0.34 11.1 13.5 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus FSA_C PF10479.9 GAM42080.1 - 1.1 7.3 11.7 1.3 7.1 11.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus LapA_dom PF06305.11 GAM42080.1 - 1.5 8.7 3.5 2.1 8.2 0.7 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Glycophorin_A PF01102.18 GAM42080.1 - 2.2 8.6 8.0 0.19 12.0 2.4 1.9 2 0 0 2 2 2 0 Glycophorin A Mid2 PF04478.12 GAM42080.1 - 3.5 7.5 8.6 1.2 8.9 4.6 2.3 2 1 0 2 2 2 0 Mid2 like cell wall stress sensor Alpha_GJ PF03229.13 GAM42080.1 - 8.8 6.9 21.8 1.3 9.6 17.8 1.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J MFS_1 PF07690.16 GAM42081.1 - 1.2e-30 106.6 20.5 1.2e-30 106.6 20.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Vma12 PF11712.8 GAM42081.1 - 0.089 12.9 0.1 0.28 11.3 0.1 1.8 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Phage_holin_3_6 PF07332.11 GAM42081.1 - 3.8 7.6 22.5 20 5.3 2.0 4.1 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PFK PF00365.20 GAM42082.1 - 1e-190 632.1 0.2 7.2e-105 350.4 0.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 GAM42082.1 - 0.025 14.2 0.1 0.11 12.1 0.1 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Lactamase_B PF00753.27 GAM42083.1 - 2.3e-19 70.2 0.1 3.2e-19 69.7 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM42083.1 - 0.00096 18.7 0.1 0.0044 16.5 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain N6-adenineMlase PF10237.9 GAM42083.1 - 0.064 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Sulfotransfer_3 PF13469.6 GAM42083.1 - 0.16 12.3 0.1 0.38 11.1 0.1 1.6 2 0 0 2 2 2 0 Sulfotransferase family adh_short PF00106.25 GAM42084.1 - 1.1e-34 119.6 0.0 1.6e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42084.1 - 2.4e-33 115.6 0.0 2.9e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM42084.1 - 1.7e-06 28.1 0.2 3.4e-05 23.8 0.1 2.5 2 1 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 GAM42084.1 - 0.0079 16.5 0.1 0.015 15.6 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ank_2 PF12796.7 GAM42085.1 - 7.7e-86 282.8 13.2 6.4e-15 55.5 0.0 8.1 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM42085.1 - 3.2e-64 212.5 6.2 1e-11 45.1 0.0 10.4 6 3 5 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM42085.1 - 7.6e-60 191.8 8.7 6.6e-05 23.0 0.0 14.7 15 1 0 15 15 15 13 Ankyrin repeat Ank_5 PF13857.6 GAM42085.1 - 2.5e-59 196.5 11.0 7.3e-09 35.7 0.0 10.3 5 4 6 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 GAM42085.1 - 5.3e-58 191.1 12.2 1.2e-05 25.5 0.0 14.2 15 0 0 15 15 15 9 Ankyrin repeat PEGA PF08308.11 GAM42085.1 - 0.0024 17.7 0.0 34 4.4 0.0 4.8 4 1 1 5 5 5 0 PEGA domain Ank_2 PF12796.7 GAM42086.1 - 1.4e-80 265.9 0.1 7.8e-16 58.4 0.0 6.2 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 GAM42086.1 - 1.2e-63 209.0 0.0 1.3e-05 25.4 0.0 11.0 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.6 GAM42086.1 - 1.2e-63 203.5 0.0 5.2e-05 23.3 0.0 11.0 11 0 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.6 GAM42086.1 - 2.2e-57 190.7 0.0 9.9e-12 45.1 0.0 6.6 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM42086.1 - 5e-46 154.2 0.1 1e-07 32.1 0.0 9.3 1 1 9 10 10 10 9 Ankyrin repeats (many copies) PEGA PF08308.11 GAM42086.1 - 0.0014 18.4 0.0 67 3.5 0.0 6.3 9 0 0 9 9 9 0 PEGA domain Mic1 PF07035.12 GAM42086.1 - 0.033 13.9 0.1 16 5.2 0.0 4.4 4 1 0 4 4 4 0 Colon cancer-associated protein Mic1-like VWA_3_C PF18571.1 GAM42086.1 - 0.039 13.8 7.6 37 4.3 0.0 7.1 9 0 0 9 9 9 0 von Willebrand factor type A C-terminal domain Asp PF00026.23 GAM42087.1 - 2.5e-48 165.1 0.6 3.1e-48 164.8 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAM42087.1 - 0.02 14.7 0.0 0.48 10.2 0.0 2.3 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal TAXi_N PF14543.6 GAM42087.1 - 0.038 14.2 0.5 2.7 8.2 0.4 2.7 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Ank_4 PF13637.6 GAM42088.1 - 2.2e-17 63.2 1.8 4.6e-05 23.9 0.0 6.9 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM42088.1 - 3.9e-16 59.4 1.9 2.5e-05 24.8 0.0 5.5 5 1 0 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 GAM42088.1 - 7.2e-12 45.2 13.2 0.059 13.8 0.2 8.8 8 2 1 9 9 9 3 Ankyrin repeat Ank_3 PF13606.6 GAM42088.1 - 1.1e-11 43.8 10.8 0.015 15.8 0.1 9.4 10 0 0 10 10 10 1 Ankyrin repeat F-box-like PF12937.7 GAM42088.1 - 1.2e-06 28.3 2.1 2.8e-06 27.1 2.1 1.7 1 0 0 1 1 1 1 F-box-like Ank_5 PF13857.6 GAM42088.1 - 2e-05 24.7 9.0 0.16 12.3 0.0 5.8 5 2 1 6 6 6 2 Ankyrin repeats (many copies) F-box PF00646.33 GAM42088.1 - 0.0091 15.9 0.3 0.0091 15.9 0.3 2.0 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 GAM42088.1 - 0.17 11.7 0.2 0.3 11.0 0.2 1.3 1 0 0 1 1 1 0 F-box DUF4646 PF15496.6 GAM42090.1 - 9.2e-09 36.0 0.1 1.9e-06 28.5 0.1 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) ISN1 PF06437.11 GAM42091.1 - 4.1e-198 658.4 0.0 4.6e-198 658.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Merozoite_SPAM PF07133.11 GAM42094.1 - 0.04 13.9 15.6 0.056 13.4 15.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) BSP_II PF05432.11 GAM42094.1 - 0.053 13.2 13.8 0.079 12.7 13.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TRAP_alpha PF03896.16 GAM42094.1 - 0.058 12.6 3.2 0.081 12.1 3.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4820 PF16091.5 GAM42094.1 - 0.086 12.2 5.0 0.11 11.8 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Nucleo_P87 PF07267.11 GAM42094.1 - 0.091 11.6 4.0 0.096 11.5 4.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 GAM42094.1 - 0.11 11.8 5.7 0.18 11.1 5.7 1.3 1 0 0 1 1 1 0 NOA36 protein Connexin PF00029.19 GAM42094.1 - 0.17 11.6 0.7 0.22 11.3 0.7 1.2 1 0 0 1 1 1 0 Connexin CENP-B_dimeris PF09026.10 GAM42094.1 - 0.18 12.2 8.6 0.35 11.3 8.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RR_TM4-6 PF06459.12 GAM42094.1 - 0.22 11.3 7.1 0.28 11.0 7.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DNA_pol_phi PF04931.13 GAM42094.1 - 0.26 9.4 7.8 0.29 9.2 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC27 PF09507.10 GAM42094.1 - 1.2 8.4 17.9 1.5 8.1 17.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 GAM42094.1 - 1.3 7.2 5.8 1.5 7.0 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 GAM42094.1 - 1.8 7.6 9.2 2.6 7.1 9.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PBP_sp32 PF07222.12 GAM42094.1 - 3.9 6.8 11.5 6.5 6.1 11.5 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Presenilin PF01080.17 GAM42094.1 - 5.6 5.6 6.4 5.8 5.6 6.4 1.2 1 0 0 1 1 1 0 Presenilin GEMIN8 PF15348.6 GAM42094.1 - 7 6.9 13.4 7.4 6.8 12.8 1.5 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Drf_FH1 PF06346.12 GAM42096.1 - 0.63 9.7 17.1 0.12 12.1 13.2 1.4 1 1 0 1 1 1 0 Formin Homology Region 1 DUF2239 PF09998.9 GAM42097.1 - 0.071 12.9 0.2 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) Med17 PF10156.9 GAM42098.1 - 1.1e-112 377.1 7.0 1.6e-112 376.6 7.0 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Fmp27 PF10344.9 GAM42098.1 - 0.027 12.6 1.9 0.04 12.0 1.9 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Protamine_P2 PF00841.19 GAM42098.1 - 0.38 11.3 1.8 42 4.7 1.3 2.6 2 0 0 2 2 2 0 Sperm histone P2 Glyco_hydro_1 PF00232.18 GAM42099.1 - 2e-73 247.4 3.7 4.5e-71 239.6 3.7 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 cNMP_binding PF00027.29 GAM42100.1 - 2.6e-29 101.1 0.7 2.7e-17 62.6 0.0 5.6 6 0 0 6 6 6 4 Cyclic nucleotide-binding domain Patatin PF01734.22 GAM42100.1 - 2.8e-17 63.6 6.8 4.2e-12 46.7 2.8 3.5 3 0 0 3 3 3 2 Patatin-like phospholipase SMN PF06003.12 GAM42100.1 - 2.4 7.4 3.8 4.6 6.4 0.1 2.3 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Fungal_trans_2 PF11951.8 GAM42101.1 - 7.3e-08 31.6 0.9 5.6e-07 28.7 0.9 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain NOA36 PF06524.12 GAM42102.1 - 4.8 6.4 12.0 9.2 5.5 12.0 1.4 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 GAM42102.1 - 5.6 6.6 8.6 14 5.3 8.6 1.7 1 0 0 1 1 1 0 FAM176 family Roughex PF06020.11 GAM42102.1 - 6.1 5.8 11.8 11 5.0 11.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Vfa1 PF08432.10 GAM42102.1 - 8.1 6.7 18.3 2 8.7 8.3 2.7 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 MFS_1 PF07690.16 GAM42103.1 - 1e-20 74.0 49.1 1.1e-20 73.8 45.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42103.1 - 1.5e-05 24.1 16.5 1.5e-05 24.1 16.5 3.7 1 1 1 3 3 3 1 Sugar (and other) transporter MMPL PF03176.15 GAM42103.1 - 0.018 14.0 0.1 0.018 14.0 0.1 2.1 2 0 0 2 2 2 0 MMPL family FAA_hydrolase PF01557.18 GAM42104.1 - 1.9e-63 214.0 0.0 3e-63 213.4 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_1 PF00561.20 GAM42104.1 - 2.1e-25 89.8 0.0 2.1e-23 83.3 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM42104.1 - 2.5e-19 69.5 0.0 4.8e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM42104.1 - 1.1e-17 65.4 0.9 2.3e-17 64.4 0.9 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Amidohydro_1 PF01979.20 GAM42104.1 - 1.1e-13 51.2 0.7 1.8e-13 50.5 0.7 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM42104.1 - 4.4e-06 26.4 3.8 0.0002 21.0 0.3 3.4 2 1 0 2 2 2 1 Amidohydrolase family BAAT_C PF08840.11 GAM42104.1 - 0.0012 18.8 0.0 0.0036 17.2 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ndr PF03096.14 GAM42104.1 - 0.0028 16.4 0.0 0.0044 15.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family UPF0227 PF05728.12 GAM42104.1 - 0.0058 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_4 PF08386.10 GAM42104.1 - 0.006 16.7 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Ser_hydrolase PF06821.13 GAM42104.1 - 0.012 15.5 0.0 1.8 8.4 0.0 2.3 1 1 1 2 2 2 0 Serine hydrolase Thioesterase PF00975.20 GAM42104.1 - 0.02 15.0 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 GAM42104.1 - 0.033 13.9 0.1 1.2 8.8 0.1 2.3 1 1 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 GAM42104.1 - 0.074 12.7 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Putative esterase Fungal_trans PF04082.18 GAM42105.1 - 1.3e-09 37.5 0.1 1.9e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM42105.1 - 6.1e-09 35.9 11.2 1.3e-08 34.8 11.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_1 PF00175.21 GAM42106.1 - 2.3e-13 50.7 0.0 4.8e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 GAM42106.1 - 3.4e-08 34.0 0.0 6.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Globin NAD_binding_6 PF08030.12 GAM42106.1 - 2.1e-07 31.2 0.1 2.9e-06 27.5 0.0 2.6 2 1 1 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 GAM42106.1 - 0.0002 21.7 0.0 0.00038 20.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NMO PF03060.15 GAM42107.1 - 1.4e-31 110.2 4.4 1.2e-20 74.2 1.8 2.7 2 1 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 GAM42107.1 - 2.5e-07 30.0 4.7 6.4e-06 25.4 2.8 2.6 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAM42107.1 - 4.2e-06 26.0 3.0 4.6e-06 25.9 1.7 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 GAM42107.1 - 6.4e-05 22.3 0.2 9.5e-05 21.7 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Aldedh PF00171.22 GAM42108.1 - 1.3e-138 462.4 0.3 1.5e-138 462.2 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 GAM42109.1 - 4.6e-39 134.3 35.8 7e-39 133.7 35.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42109.1 - 1.6e-12 47.0 9.9 4.2e-12 45.7 9.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MARVEL PF01284.23 GAM42110.1 - 3.6e-10 40.0 12.6 4.7e-10 39.7 12.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain RasGAP PF00616.19 GAM42110.1 - 0.043 13.5 0.2 0.06 13.0 0.2 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF5504 PF17608.2 GAM42110.1 - 0.19 11.8 4.2 0.22 11.6 3.7 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5504) Mtc PF03820.17 GAM42110.1 - 0.9 8.5 6.0 1.4 7.9 0.9 2.0 1 1 1 2 2 2 0 Tricarboxylate carrier SUR7 PF06687.12 GAM42110.1 - 2.3 7.8 10.8 3 7.4 1.0 2.2 1 1 1 2 2 2 0 SUR7/PalI family DUF202 PF02656.15 GAM42110.1 - 2.7 8.5 9.0 2.9 8.4 2.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF2069 PF09842.9 GAM42110.1 - 6.1 7.1 12.0 0.34 11.1 1.2 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2069) GRIP PF01465.20 GAM42111.1 - 3e-16 59.1 0.4 7.2e-16 57.8 0.4 1.7 1 0 0 1 1 1 1 GRIP domain Acetyltransf_1 PF00583.25 GAM42111.1 - 5.8e-15 55.6 0.0 1.6e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAM42111.1 - 1.3e-06 28.2 0.0 4.7e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 GAM42111.1 - 1.9e-05 25.0 0.0 4.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM42111.1 - 6.6e-05 22.9 0.0 0.00025 21.0 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GAS PF13851.6 GAM42111.1 - 9.7e-05 21.8 19.8 9.7e-05 21.8 19.8 11.1 3 2 7 10 10 10 4 Growth-arrest specific micro-tubule binding DUF4201 PF13870.6 GAM42111.1 - 0.0012 18.6 13.0 0.0012 18.6 13.0 10.0 2 2 7 10 10 9 4 Domain of unknown function (DUF4201) AAA_13 PF13166.6 GAM42111.1 - 0.0014 17.3 21.1 0.0014 17.3 21.1 6.0 2 2 3 5 5 5 2 AAA domain Spc7 PF08317.11 GAM42111.1 - 0.0015 17.5 20.2 0.0015 17.5 20.2 8.4 2 2 5 8 8 8 4 Spc7 kinetochore protein Acetyltransf_3 PF13302.7 GAM42111.1 - 0.0019 18.9 0.0 0.0092 16.7 0.0 2.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CENP-F_leu_zip PF10473.9 GAM42111.1 - 0.0035 17.4 15.8 0.0035 17.4 15.8 10.3 3 2 8 11 11 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 GAM42111.1 - 0.0041 17.3 26.5 0.0041 17.3 26.5 10.4 2 2 9 11 11 8 2 Tropomyosin like Seryl_tRNA_N PF02403.22 GAM42111.1 - 0.0082 16.4 11.5 0.0082 16.4 11.5 11.8 4 3 10 14 14 13 2 Seryl-tRNA synthetase N-terminal domain Csm1_N PF18504.1 GAM42111.1 - 0.0084 16.4 5.5 0.0084 16.4 5.5 15.6 5 3 13 18 18 18 1 Csm1 N-terminal domain DivIC PF04977.15 GAM42111.1 - 0.019 14.7 0.4 0.019 14.7 0.4 15.2 5 4 9 14 14 14 0 Septum formation initiator Acetyltransf_4 PF13420.7 GAM42111.1 - 0.75 9.9 0.0 0.75 9.9 0.0 3.1 4 1 0 4 4 1 0 Acetyltransferase (GNAT) domain Fez1 PF06818.15 GAM42111.1 - 0.76 10.2 159.0 5.9 7.3 14.1 8.6 1 1 7 9 9 9 0 Fez1 ATG16 PF08614.11 GAM42111.1 - 2.7 8.2 185.0 0.77 10.0 21.0 9.9 3 2 6 9 9 9 0 Autophagy protein 16 (ATG16) SNARE PF05739.19 GAM42111.1 - 4.2 7.4 10.4 0.28 11.2 0.2 3.7 3 0 0 3 3 3 0 SNARE domain Peptidase_S64 PF08192.11 GAM42112.1 - 0.19 10.2 0.0 0.19 10.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S64 FtsH_ext PF06480.15 GAM42112.1 - 2.7 8.4 4.4 0.92 9.9 0.5 2.2 2 0 0 2 2 2 0 FtsH Extracellular SKG6 PF08693.10 GAM42113.1 - 8.7e-07 28.2 5.1 1.9e-06 27.2 5.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 GAM42113.1 - 0.00018 21.3 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) ANAPC1 PF12859.7 GAM42116.1 - 0.16 12.6 0.5 0.24 11.9 0.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Anoctamin PF04547.12 GAM42117.1 - 2.3e-110 369.6 10.9 3.6e-110 368.9 10.9 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel Brr6_like_C_C PF10104.9 GAM42117.1 - 1e-36 125.7 1.6 4.3e-36 123.6 0.7 2.5 2 0 0 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain Pex2_Pex12 PF04757.14 GAM42117.1 - 0.083 12.5 0.1 0.24 11.0 0.1 1.8 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region DUF443 PF04276.12 GAM42117.1 - 0.81 9.5 6.8 20 4.9 5.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF443) MFS_1 PF07690.16 GAM42117.1 - 0.96 8.3 12.5 0.64 8.9 9.6 2.1 2 1 0 2 2 2 0 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM42118.1 - 6.6e-15 54.9 0.1 1.3e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Caroten_synth PF04240.12 GAM42118.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Carotenoid biosynthesis protein Glyco_transf_20 PF00982.21 GAM42119.1 - 2.2e-167 557.5 0.0 3.4e-167 556.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 adh_short PF00106.25 GAM42119.1 - 9.9e-15 54.5 0.0 2.1e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM42119.1 - 1.5e-10 41.3 0.1 3.6e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 GAM42119.1 - 7.5e-07 28.9 0.1 2.9e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Glyco_transf_5 PF08323.11 GAM42119.1 - 0.022 14.4 0.1 0.045 13.4 0.1 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain Glyco_trans_1_2 PF13524.6 GAM42119.1 - 0.084 13.3 0.0 0.33 11.4 0.0 2.0 1 0 0 1 1 1 0 Glycosyl transferases group 1 Ras PF00071.22 GAM42120.1 - 5.9e-40 136.5 0.0 6.8e-37 126.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 GAM42120.1 - 2.8e-30 105.0 0.0 4.5e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM42120.1 - 5.4e-11 42.2 0.0 1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM42120.1 - 1.4e-05 25.2 0.1 2.1e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAM42120.1 - 0.0022 18.4 0.0 0.004 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAM42120.1 - 0.0038 17.1 0.0 0.0082 16.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase SRPRB PF09439.10 GAM42120.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 GAM42120.1 - 0.024 14.9 0.1 0.097 12.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 GAM42120.1 - 0.035 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 GAM42120.1 - 0.061 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 GAM42120.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Dynamin family AAA_24 PF13479.6 GAM42120.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain FMN_dh PF01070.18 GAM42121.1 - 2.8e-124 414.7 0.1 3.4e-124 414.4 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 GAM42121.1 - 6.6e-24 83.9 0.0 1.5e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 GAM42121.1 - 2.9e-08 33.3 0.0 4.6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 GAM42121.1 - 0.00012 21.3 0.5 0.00023 20.3 0.1 1.7 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 GAM42121.1 - 0.0005 19.6 0.3 0.001 18.6 0.1 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 GAM42121.1 - 0.032 13.7 2.4 0.71 9.3 0.2 2.5 2 1 0 3 3 3 0 Histidine biosynthesis protein G3P_antiterm PF04309.12 GAM42121.1 - 0.17 11.3 0.0 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Metallophos PF00149.28 GAM42122.1 - 4.8e-11 43.5 4.6 2.8e-10 41.0 4.6 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM42122.1 - 1e-05 25.8 0.4 0.00018 21.7 0.3 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.16 GAM42123.1 - 5.4e-46 157.1 24.6 5.4e-46 157.1 24.6 1.8 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42123.1 - 3.1e-09 36.2 10.2 3.1e-09 36.2 10.2 3.2 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAM42123.1 - 4.7e-08 31.9 3.9 8.9e-08 31.0 3.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2_4 PF16082.5 GAM42123.1 - 0.032 13.9 0.0 0.17 11.6 0.0 2.2 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF5316 PF17247.2 GAM42123.1 - 0.44 10.6 3.3 4.5 7.3 0.2 3.9 3 1 0 3 3 3 0 Family of unknown function (DUF5316) Methyltransf_2 PF00891.18 GAM42125.1 - 0.024 13.9 0.0 0.048 13.0 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain HTH_20 PF12840.7 GAM42125.1 - 0.025 14.6 0.2 0.059 13.4 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 GAM42125.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 GAM42125.1 - 0.069 13.1 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 HTH domain DUF1772 PF08592.11 GAM42126.1 - 5.1e-19 68.9 0.4 6.1e-19 68.7 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) MFS_1 PF07690.16 GAM42127.1 - 2e-54 184.9 40.4 2e-54 184.9 40.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42127.1 - 3.1e-17 62.6 6.1 3.1e-17 62.6 6.1 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAM42127.1 - 7.3e-09 34.6 2.5 7.3e-09 34.6 2.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 GAM42127.1 - 5.9e-08 31.5 7.8 1e-07 30.8 7.8 1.5 1 1 0 1 1 1 1 Transmembrane secretion effector MFS_4 PF06779.14 GAM42127.1 - 5e-06 26.0 6.4 5e-06 26.0 6.4 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2583 PF10762.9 GAM42127.1 - 0.49 10.9 3.3 0.49 10.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Thioesterase PF00975.20 GAM42128.1 - 1.7e-15 57.7 0.0 2e-14 54.3 0.0 2.2 1 1 0 1 1 1 1 Thioesterase domain Fungal_trans PF04082.18 GAM42128.1 - 3.6e-11 42.6 0.3 6.1e-11 41.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2974 PF11187.8 GAM42128.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Malectin_like PF12819.7 GAM42128.1 - 0.19 10.9 1.3 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Malectin-like domain Pkinase PF00069.25 GAM42129.1 - 7.4e-06 25.5 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM42129.1 - 0.00045 19.6 0.0 0.00065 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM42130.1 - 7.7e-21 74.6 0.0 2.6e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Ank_2 PF12796.7 GAM42130.1 - 8.2e-19 68.0 0.0 7e-11 42.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 GAM42130.1 - 6.2e-18 65.0 0.0 1.2e-16 60.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 GAM42130.1 - 1.4e-13 49.7 0.1 0.0045 17.4 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 GAM42130.1 - 8.1e-13 48.6 0.0 7e-05 23.3 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM42130.1 - 1.1e-12 47.9 0.3 8e-05 22.8 0.0 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAM42130.1 - 1.8e-11 43.9 0.3 0.0053 17.2 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat MID_MedPIWI PF18296.1 GAM42130.1 - 0.03 14.1 0.4 0.05 13.4 0.4 1.3 1 0 0 1 1 1 0 MID domain of medPIWI Pox_ser-thr_kin PF05445.11 GAM42130.1 - 0.16 10.9 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 GAM42131.1 - 5.1e-40 137.5 0.0 4.6e-22 78.6 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM42131.1 - 3.7e-14 52.6 0.2 1.1e-09 38.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM42131.1 - 0.058 12.2 0.3 0.085 11.6 0.3 1.5 1 1 0 1 1 1 0 Fungal protein kinase Bud13 PF09736.9 GAM42132.1 - 1.4e-49 168.3 6.3 1.4e-49 168.3 6.3 3.2 3 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Synaptobrevin PF00957.21 GAM42132.1 - 6.3e-14 51.5 1.0 1.4e-13 50.4 1.0 1.6 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAM42132.1 - 2.3e-13 50.0 0.0 5.3e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sec63 PF02889.16 GAM42133.1 - 2.1e-127 423.6 0.4 2.6e-77 259.5 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 GAM42133.1 - 4.3e-52 176.4 0.4 2.5e-26 92.5 0.7 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 GAM42133.1 - 1.1e-21 77.6 0.0 1.4e-10 41.4 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAM42133.1 - 2.6e-16 59.9 0.0 1.6e-06 28.4 0.0 4.5 4 2 0 4 4 4 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAM42133.1 - 1e-08 35.5 0.2 0.00034 20.9 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GAM42133.1 - 8.1e-08 32.2 0.2 0.0041 16.9 0.3 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GAM42133.1 - 1.1e-05 25.8 0.9 0.0045 17.3 0.8 2.7 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 GAM42133.1 - 0.0015 18.7 0.0 0.0052 16.9 0.0 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain IstB_IS21 PF01695.17 GAM42133.1 - 0.028 14.2 0.1 5.5 6.7 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein TniB PF05621.11 GAM42133.1 - 0.075 12.4 0.5 17 4.8 0.1 3.5 4 0 0 4 4 4 0 Bacterial TniB protein AAA_7 PF12775.7 GAM42133.1 - 0.11 12.0 0.0 12 5.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 GAM42133.1 - 3.9 7.8 5.4 7.8 6.9 0.0 3.8 4 0 0 4 4 4 0 AAA ATPase domain Profilin PF00235.19 GAM42135.1 - 9.2e-33 113.2 0.1 1e-32 113.1 0.1 1.0 1 0 0 1 1 1 1 Profilin Ank_2 PF12796.7 GAM42136.1 - 1.1e-34 118.8 1.6 3.1e-11 43.7 0.3 5.6 2 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM42136.1 - 6.4e-28 93.7 4.4 0.00057 20.1 0.0 11.4 11 0 0 11 11 10 5 Ankyrin repeat Ank_4 PF13637.6 GAM42136.1 - 2.5e-26 91.7 1.7 0.00053 20.5 0.0 8.2 4 4 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 GAM42136.1 - 5.7e-23 80.3 10.7 0.012 16.0 0.1 9.8 8 1 1 9 9 9 6 Ankyrin repeat AAA PF00004.29 GAM42136.1 - 2e-19 70.3 0.0 2e-14 54.2 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Ank_5 PF13857.6 GAM42136.1 - 5.6e-18 64.8 5.1 0.027 14.8 0.1 8.4 4 2 6 10 10 9 6 Ankyrin repeats (many copies) AAA_22 PF13401.6 GAM42136.1 - 2.2e-11 44.2 0.2 3.7e-07 30.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 GAM42136.1 - 2.4e-10 41.1 5.1 7.4e-05 23.2 0.5 4.2 2 2 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 GAM42136.1 - 3.2e-10 40.2 0.2 1.2e-08 35.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 GAM42136.1 - 1.6e-05 24.5 0.0 0.072 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 GAM42136.1 - 2.8e-05 24.2 0.2 0.22 11.6 0.9 3.9 3 1 0 3 3 2 1 AAA domain AAA_18 PF13238.6 GAM42136.1 - 9.2e-05 23.0 0.3 0.1 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GAM42136.1 - 0.00054 20.3 0.1 0.016 15.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 GAM42136.1 - 0.0016 17.7 5.0 0.037 13.2 0.0 3.6 3 0 0 3 3 3 1 NB-ARC domain AAA_33 PF13671.6 GAM42136.1 - 0.0026 17.9 0.2 1.8 8.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 GAM42136.1 - 0.0068 16.4 0.1 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 GAM42136.1 - 0.0082 15.4 0.2 0.096 11.9 0.0 2.5 2 1 1 3 3 3 1 KAP family P-loop domain TsaE PF02367.17 GAM42136.1 - 0.026 14.5 0.0 0.38 10.8 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 GAM42136.1 - 0.051 13.9 0.1 15 5.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain TrbH PF07283.11 GAM42136.1 - 0.13 12.5 0.2 0.64 10.2 0.0 2.2 2 0 0 2 2 2 0 Conjugal transfer protein TrbH AAA_7 PF12775.7 GAM42136.1 - 0.16 11.5 0.5 7.8 6.0 0.0 3.3 3 1 0 3 3 3 0 P-loop containing dynein motor region DUF4795 PF16043.5 GAM42136.1 - 1.3 8.6 5.0 5.6 6.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Fungal_trans_2 PF11951.8 GAM42137.1 - 3.8e-10 39.1 0.0 5.4e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain HU-DNA_bdg PF14848.6 GAM42137.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA-binding domain 2OG-FeII_Oxy_3 PF13640.6 GAM42138.1 - 0.066 14.1 0.0 0.11 13.4 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily YL1_C PF08265.11 GAM42139.1 - 8.2e-15 54.3 0.2 1.4e-14 53.6 0.2 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Actin PF00022.19 GAM42140.1 - 1.2e-56 192.1 0.0 1e-31 110.0 0.0 2.3 2 0 0 2 2 2 2 Actin bZIP_1 PF00170.21 GAM42141.1 - 3.1e-09 36.8 7.5 9.3e-09 35.3 7.5 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAM42141.1 - 0.058 13.5 10.9 2.3 8.3 9.2 2.9 2 1 0 2 2 2 0 Basic region leucine zipper HALZ PF02183.18 GAM42141.1 - 3.4 8.0 7.0 0.29 11.4 1.4 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper E1-E2_ATPase PF00122.20 GAM42142.1 - 1.3e-40 138.9 7.6 2e-40 138.3 2.2 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAM42142.1 - 9.6e-38 129.7 0.7 9.6e-38 129.7 0.7 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAM42142.1 - 4e-22 79.5 0.0 6.7e-12 46.1 0.0 2.8 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM42142.1 - 2.8e-13 49.7 0.0 5.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAM42142.1 - 1.7e-12 46.9 0.0 4.1e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2157 PF09925.9 GAM42142.1 - 0.0036 17.1 7.2 0.029 14.2 0.1 3.1 4 0 0 4 4 4 2 Predicted membrane protein (DUF2157) Hydrolase_3 PF08282.12 GAM42142.1 - 0.0037 17.0 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.9 GAM42142.1 - 0.0092 16.4 0.7 0.045 14.2 0.7 2.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) DoxX PF07681.12 GAM42142.1 - 1.9 9.1 6.3 1.5 9.5 0.1 3.1 2 0 0 2 2 2 0 DoxX TMEM43 PF07787.12 GAM42142.1 - 3.1 7.1 4.5 3 7.2 0.3 2.4 2 0 0 2 2 2 0 Transmembrane protein 43 SnoaL PF07366.12 GAM42143.1 - 6.4e-05 22.7 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.18 GAM42143.1 - 0.0079 15.8 0.5 0.044 13.3 0.5 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Methyltransf_2 PF00891.18 GAM42144.1 - 8.7e-28 97.1 0.0 1.3e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 GAM42144.1 - 0.0062 17.3 0.1 0.019 15.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM42144.1 - 0.016 15.9 0.1 0.047 14.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain CheR PF01739.18 GAM42144.1 - 0.05 13.1 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TPR_10 PF13374.6 GAM42145.1 - 9.9e-52 171.5 8.3 6.1e-07 29.1 0.0 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 GAM42145.1 - 2.5e-51 171.9 23.9 1.8e-11 44.2 0.0 7.0 3 2 5 8 8 7 7 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM42145.1 - 4.6e-20 72.3 2.8 9.1e-09 35.1 0.2 3.3 1 1 2 3 3 3 3 MalT-like TPR region PNP_UDP_1 PF01048.20 GAM42145.1 - 4.9e-13 48.9 0.0 7.9e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_2 PF07719.17 GAM42145.1 - 1.1e-12 47.0 15.7 0.059 13.5 0.2 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat NB-ARC PF00931.22 GAM42145.1 - 1.8e-09 37.2 0.1 5.8e-09 35.5 0.1 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 GAM42145.1 - 2.2e-09 37.9 0.1 5.9e-09 36.5 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain TPR_7 PF13176.6 GAM42145.1 - 4.9e-08 32.5 14.8 0.48 10.6 0.1 8.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM42145.1 - 1.2e-07 31.2 14.4 2.1 8.3 0.0 7.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAM42145.1 - 2.4e-07 31.2 7.5 2.4 8.7 0.4 7.4 6 1 1 7 7 7 2 Tetratricopeptide repeat AAA_22 PF13401.6 GAM42145.1 - 0.00046 20.5 0.0 0.0041 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 GAM42145.1 - 0.00076 19.5 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_16 PF13432.6 GAM42145.1 - 0.00085 19.9 6.0 2.9 8.6 0.2 6.3 6 2 0 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAM42145.1 - 0.0014 19.0 2.7 27 5.8 0.1 6.0 7 0 0 7 7 4 0 Tetratricopeptide repeat NACHT PF05729.12 GAM42145.1 - 0.0039 17.1 0.1 0.022 14.7 0.1 2.3 1 1 0 1 1 1 1 NACHT domain TPR_14 PF13428.6 GAM42145.1 - 0.013 16.2 16.5 3.3 8.8 0.0 8.7 9 2 1 10 10 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAM42145.1 - 0.05 14.0 7.3 1.6e+02 3.0 0.0 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat TrwB_AAD_bind PF10412.9 GAM42145.1 - 0.056 12.4 0.0 0.16 10.8 0.0 1.7 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 GAM42145.1 - 0.07 13.7 0.0 0.29 11.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 GAM42145.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MeaB PF03308.16 GAM42145.1 - 0.16 11.0 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TPR_8 PF13181.6 GAM42145.1 - 0.19 12.0 15.1 8.2 6.9 0.1 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat RPN6_N PF18055.1 GAM42145.1 - 1.4 9.2 5.5 29 5.1 0.3 3.8 3 1 2 5 5 5 0 26S proteasome regulatory subunit RPN6 N-terminal domain Rbsn PF11464.8 GAM42145.1 - 6.2 6.6 6.2 2.4 8.0 0.1 3.4 4 0 0 4 4 3 0 Rabenosyn Rab binding domain DEAD PF00270.29 GAM42146.1 - 1.4e-15 57.5 0.0 3.1e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAM42146.1 - 1.2e-09 38.4 0.0 4.1e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAM42146.1 - 6.9e-07 29.6 0.0 5.2e-06 26.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhoH PF02562.16 GAM42146.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein GH115_C PF17829.1 GAM42146.1 - 0.21 11.4 0.9 2.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Gylcosyl hydrolase family 115 C-terminal domain AChE_tetra PF08674.10 GAM42146.1 - 0.24 11.1 6.4 0.59 9.9 6.4 1.6 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain PLDc_2 PF13091.6 GAM42147.1 - 2.6e-22 79.2 0.0 2.6e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain FAM83 PF07894.12 GAM42147.1 - 0.0012 18.5 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 2 FAM83 A-H PLDc PF00614.22 GAM42147.1 - 0.006 16.7 0.5 2.6 8.4 0.1 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif STG PF15809.5 GAM42150.1 - 0.0071 16.5 0.4 0.01 15.9 0.4 1.3 1 0 0 1 1 1 1 Simian taste bud-specific gene product family SLT PF01464.20 GAM42150.1 - 0.042 13.5 0.3 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 Transglycosylase SLT domain Lysozyme_like PF13702.6 GAM42150.1 - 0.13 11.9 0.0 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Lysozyme-like Pectate_lyase_3 PF12708.7 GAM42151.1 - 2.3e-51 174.7 10.4 2.5e-43 148.4 5.7 2.6 2 1 0 2 2 2 2 Pectate lyase superfamily protein Beta_helix PF13229.6 GAM42151.1 - 0.0022 17.9 7.9 0.0022 17.9 7.9 2.6 3 0 0 3 3 3 1 Right handed beta helix region End_N_terminal PF12218.8 GAM42151.1 - 0.037 13.7 1.5 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Sterol_MT_C PF08498.10 GAM42152.1 - 2e-29 101.7 0.7 3.2e-29 101.0 0.7 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 GAM42152.1 - 8.3e-22 77.7 0.0 1.8e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM42152.1 - 1e-19 71.0 0.0 3.3e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM42152.1 - 1.1e-18 67.4 0.0 1.7e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAM42152.1 - 1.7e-13 50.5 0.0 2.6e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 GAM42152.1 - 3.4e-12 46.5 0.0 5.8e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM42152.1 - 1.8e-10 40.6 0.0 2.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAM42152.1 - 4.8e-09 36.9 0.0 1.1e-08 35.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 GAM42152.1 - 8e-06 24.7 0.0 1.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 GAM42152.1 - 0.00034 20.4 0.0 0.00059 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 GAM42152.1 - 0.0016 17.9 0.0 0.0036 16.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 GAM42152.1 - 0.0019 17.5 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_15 PF09445.10 GAM42152.1 - 0.0039 16.8 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 GAM42152.1 - 0.015 15.0 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 GAM42152.1 - 0.036 14.1 0.7 0.091 12.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.12 GAM42152.1 - 0.037 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 GAM42152.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 GAM42152.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB RRM_1 PF00076.22 GAM42153.1 - 5.8e-09 35.7 0.0 9.2e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM42153.1 - 0.00013 21.7 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 GAM42153.1 - 0.00054 19.9 0.0 0.00087 19.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Complex1_LYR PF05347.15 GAM42154.1 - 3.5e-06 27.0 1.3 4.2e-06 26.7 0.4 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) MOSC PF03473.17 GAM42154.1 - 0.01 15.8 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 0 MOSC domain Complex1_LYR_2 PF13233.6 GAM42154.1 - 0.084 13.6 1.8 0.1 13.4 1.8 1.3 1 1 0 1 1 1 0 Complex1_LYR-like RAC_head PF16717.5 GAM42155.1 - 5.6e-31 107.4 8.1 5.6e-31 107.4 8.1 3.3 2 1 0 2 2 2 1 Ribosome-associated complex head domain DnaJ PF00226.31 GAM42155.1 - 2.8e-18 65.8 4.1 4.3e-18 65.2 1.8 2.7 2 0 0 2 2 2 1 DnaJ domain DUF1178 PF06676.11 GAM42155.1 - 2.9 8.3 0.0 2.9 8.3 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1178) CemA PF03040.14 GAM42155.1 - 7.2 6.5 6.4 14 5.5 6.4 1.4 1 0 0 1 1 1 0 CemA family Aldo_ket_red PF00248.21 GAM42156.1 - 3.5e-69 233.2 0.0 4e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_tail_X PF05489.12 GAM42156.1 - 0.17 11.6 0.0 0.44 10.2 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X Amidase PF01425.21 GAM42157.1 - 9.8e-34 117.1 0.2 1.4e-33 116.5 0.2 1.2 1 0 0 1 1 1 1 Amidase ThrE PF06738.12 GAM42158.1 - 8.5e-74 247.9 19.0 2.5e-67 226.7 5.5 2.4 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 GAM42158.1 - 1.7e-10 41.1 9.6 1.7e-10 41.1 9.6 3.5 2 2 0 2 2 2 1 Threonine/Serine exporter, ThrE tRNA-synt_1c PF00749.21 GAM42159.1 - 6.6e-89 297.9 0.8 9.5e-88 294.1 0.8 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAM42159.1 - 3.2e-28 98.8 0.0 1.1e-27 97.0 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain PseudoU_synth_2 PF00849.22 GAM42159.1 - 0.072 13.2 0.1 15 5.6 0.0 2.4 2 0 0 2 2 2 0 RNA pseudouridylate synthase LepB_GAP_N PF18172.1 GAM42159.1 - 0.15 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 LepB GAP domain N-terminal subdomain Ribosomal_60s PF00428.19 GAM42159.1 - 2.1 9.0 16.7 4.7 7.9 16.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein FMO-like PF00743.19 GAM42160.1 - 4.3e-39 134.3 0.0 1.5e-15 56.7 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAM42160.1 - 5.4e-17 62.0 0.0 7.9e-13 48.3 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM42160.1 - 1.7e-13 50.5 0.0 2.3e-12 46.8 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM42160.1 - 2.9e-09 37.0 0.5 0.00014 21.6 0.2 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM42160.1 - 1.5e-08 34.8 0.0 5.6e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAM42160.1 - 2.1e-08 33.9 0.0 0.00024 20.5 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 GAM42160.1 - 3.4e-08 33.0 2.1 3e-06 26.6 0.1 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAM42160.1 - 7e-08 32.6 2.2 0.001 19.1 0.0 4.5 4 1 0 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.14 GAM42160.1 - 1.9e-07 30.1 0.1 0.0015 17.3 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 GAM42160.1 - 2e-05 25.1 2.9 0.00047 20.7 0.0 3.4 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 GAM42160.1 - 2.2e-05 24.6 0.0 0.17 11.9 0.0 3.1 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 GAM42160.1 - 0.00013 21.3 0.1 0.0052 16.1 0.1 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 GAM42160.1 - 0.00045 19.4 0.6 0.024 13.7 0.6 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAM42160.1 - 0.0047 16.2 0.1 0.014 14.7 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 GAM42160.1 - 0.027 14.1 0.0 0.29 10.8 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 GAM42160.1 - 0.034 13.5 0.2 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 GAM42160.1 - 0.07 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 GAM42160.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GST_N PF02798.20 GAM42161.1 - 5.4e-14 52.3 0.0 9.9e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAM42161.1 - 6.4e-12 45.7 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM42161.1 - 7.6e-12 45.3 0.0 1.6e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM42161.1 - 1.2e-11 44.8 0.0 3e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM42161.1 - 8.4e-10 38.7 0.0 1.4e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM42161.1 - 0.00014 21.8 0.0 0.00039 20.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain KR PF08659.10 GAM42162.1 - 3.7e-61 206.2 0.0 1.3e-60 204.3 0.0 2.0 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 GAM42162.1 - 4.7e-55 186.9 0.0 7.3e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 GAM42162.1 - 5.9e-48 163.6 0.0 2e-32 112.8 0.0 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAM42162.1 - 3.3e-46 158.3 0.2 9.9e-46 156.7 0.2 1.8 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM42162.1 - 5.7e-39 132.8 0.1 1.6e-38 131.3 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 GAM42162.1 - 6.4e-17 62.1 0.0 3.5e-16 59.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAM42162.1 - 2.2e-16 60.3 0.1 1e-12 48.5 0.1 2.8 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 GAM42162.1 - 1.3e-15 57.6 0.0 5.1e-15 55.6 0.0 2.1 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM42162.1 - 2.7e-15 57.6 0.0 2.1e-14 54.7 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 GAM42162.1 - 1.2e-13 51.0 0.1 4.3e-12 45.9 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 GAM42162.1 - 2.3e-11 43.8 0.0 4.8e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 GAM42162.1 - 2.1e-09 37.3 0.0 5.3e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_25 PF13649.6 GAM42162.1 - 1.3e-08 35.4 0.0 1.1e-07 32.4 0.0 2.8 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.12 GAM42162.1 - 3.2e-08 33.4 1.1 2.1e-07 30.8 0.3 2.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 GAM42162.1 - 2e-07 31.5 0.0 7.5e-07 29.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 GAM42162.1 - 5.1e-06 26.8 0.1 1.7e-05 25.1 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 GAM42162.1 - 0.00026 20.8 0.0 0.0007 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 GAM42162.1 - 0.017 14.9 0.2 0.24 11.1 0.2 2.4 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Ubie_methyltran PF01209.18 GAM42162.1 - 0.033 13.5 0.0 0.091 12.1 0.0 1.7 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.15 GAM42162.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DHDPS PF00701.22 GAM42163.1 - 8.1e-39 133.0 0.0 9.8e-39 132.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.22 GAM42163.1 - 0.026 14.5 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 PA domain Sugar_tr PF00083.24 GAM42164.1 - 6.5e-86 289.0 24.1 1.9e-85 287.4 24.1 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM42164.1 - 5.6e-21 74.8 35.8 2e-18 66.4 15.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 GAM42164.1 - 0.54 10.5 4.8 1.8 8.9 4.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Fungal_trans PF04082.18 GAM42165.1 - 5.9e-28 97.6 0.1 1.2e-27 96.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM42165.1 - 3.9e-07 30.1 9.1 9.7e-07 28.8 9.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FSH1 PF03959.13 GAM42166.1 - 1.2e-12 47.9 0.0 5.5e-12 45.8 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Glyco_hydro_65N PF03636.15 GAM42167.1 - 2.4e-24 86.2 0.0 4.9e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 GAM42167.1 - 5.9e-23 81.4 3.4 1.6e-16 60.1 0.5 3.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain F5_F8_type_C PF00754.25 GAM42167.1 - 2.7e-05 24.3 0.2 2.7e-05 24.3 0.2 2.3 2 1 0 2 2 2 1 F5/8 type C domain Glyco_hydro_30 PF02055.16 GAM42168.1 - 6.2e-32 110.9 3.2 9.5e-32 110.3 3.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 GAM42168.1 - 2.5e-09 37.2 0.5 6.3e-09 35.9 0.5 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 GAM42168.1 - 0.0003 20.1 0.8 0.00088 18.6 0.1 2.1 1 1 0 2 2 2 1 Glycosyl hydrolase family 59 AA_permease_2 PF13520.6 GAM42169.1 - 1.2e-88 297.9 41.7 1.2e-88 297.9 41.7 1.3 1 1 0 1 1 1 1 Amino acid permease PBP PF01161.20 GAM42170.1 - 0.00031 21.1 0.1 0.00038 20.8 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Zn_clus PF00172.18 GAM42171.1 - 1.9e-07 31.1 7.2 3.7e-07 30.1 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.13 GAM42172.1 - 3.1e-19 70.1 0.0 4.1e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HGWP PF03578.15 GAM42172.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 HGWP repeat Helitron_like_N PF14214.6 GAM42173.1 - 4.7e-30 105.2 0.0 1.1e-29 104.0 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 GAM42173.1 - 7.5e-21 74.7 0.1 6.4e-20 71.6 0.1 2.0 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 GAM42173.1 - 8.9e-12 45.1 0.0 2.4e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM42173.1 - 1.4e-09 38.4 0.0 3.7e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Pentapeptide_4 PF13599.6 GAM42173.1 - 0.00045 20.3 1.6 0.92 9.7 0.0 4.0 3 1 1 4 4 4 1 Pentapeptide repeats (9 copies) Ploopntkinase3 PF18751.1 GAM42173.1 - 0.28 11.1 1.1 1.3 8.9 0.2 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MFS_1 PF07690.16 GAM42175.1 - 6e-38 130.7 47.3 1.7e-37 129.2 47.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.22 GAM42175.1 - 3.4e-27 95.3 0.0 5.1e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRI12 PF06609.13 GAM42175.1 - 9.3e-11 40.8 10.9 9.3e-11 40.8 10.9 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 GAM42176.1 - 1.1e-45 156.3 0.0 1.4e-45 156.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 GAM42177.1 - 2e-33 115.8 43.4 2e-33 115.8 43.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Desulfoferrod_N PF06397.12 GAM42177.1 - 0.04 13.5 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Adeno_E4_34 PF04528.13 GAM42177.1 - 0.066 13.1 0.5 0.26 11.1 0.1 2.1 2 0 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region Methyltransf_25 PF13649.6 GAM42178.1 - 2.5e-24 85.8 0.0 7e-24 84.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM42178.1 - 2.7e-22 79.2 0.0 6.4e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM42178.1 - 5.6e-22 78.2 0.0 2.3e-21 76.3 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM42178.1 - 7.2e-17 61.7 0.0 3.3e-16 59.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM42178.1 - 1.2e-14 54.3 0.0 2.8e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAM42178.1 - 4.8e-14 52.9 0.0 1.3e-13 51.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain AAA PF00004.29 GAM42178.1 - 4.7e-11 43.2 0.0 1.1e-10 42.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MTS PF05175.14 GAM42178.1 - 3.2e-07 30.1 0.0 7.5e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 GAM42178.1 - 7e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 GAM42178.1 - 3e-05 23.5 0.0 5.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 GAM42178.1 - 0.00013 21.9 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAM42178.1 - 0.00024 20.6 0.0 0.00056 19.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 GAM42178.1 - 0.0004 19.9 0.0 0.0028 17.1 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase AAA_16 PF13191.6 GAM42178.1 - 0.00097 19.6 0.0 0.0027 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM42178.1 - 0.0042 17.4 0.0 0.0092 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain MetW PF07021.12 GAM42178.1 - 0.0042 16.7 0.0 0.072 12.7 0.0 2.7 3 1 0 3 3 3 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 GAM42178.1 - 0.0061 16.6 0.0 0.017 15.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Torsin PF06309.11 GAM42178.1 - 0.0072 16.4 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 Torsin CheR PF01739.18 GAM42178.1 - 0.011 15.3 0.0 1.3 8.5 0.0 2.4 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain AAA_30 PF13604.6 GAM42178.1 - 0.012 15.4 0.1 0.048 13.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain Methyltransf_9 PF08003.11 GAM42178.1 - 0.014 14.4 0.0 0.033 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) AAA_5 PF07728.14 GAM42178.1 - 0.016 15.2 0.0 0.048 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Methyltransf_29 PF03141.16 GAM42178.1 - 0.052 12.1 0.0 0.14 10.7 0.0 1.5 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AAA_33 PF13671.6 GAM42178.1 - 0.071 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Methyltransf_15 PF09445.10 GAM42178.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MFS_1 PF07690.16 GAM42179.1 - 9e-20 70.9 7.4 1.3e-19 70.4 5.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42179.1 - 2.1e-11 43.4 2.4 6e-10 38.6 0.0 3.0 3 1 1 4 4 4 2 Sugar (and other) transporter GDC-P PF02347.16 GAM42180.1 - 1.8e-172 574.0 0.0 5.5e-161 536.2 0.0 2.6 2 1 0 2 2 2 2 Glycine cleavage system P-protein Amidohydro_1 PF01979.20 GAM42180.1 - 2.1e-62 211.4 0.0 3.8e-62 210.6 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM42180.1 - 1.4e-09 37.9 0.7 3.8e-07 29.9 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Beta_elim_lyase PF01212.21 GAM42180.1 - 6e-07 29.0 0.2 1.5e-06 27.7 0.2 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase tRNA_int_end_N2 PF12928.7 GAM42180.1 - 0.17 12.1 0.0 0.97 9.7 0.0 2.3 2 0 0 2 2 2 0 tRNA-splicing endonuclease subunit sen54 N-term Peptidase_S28 PF05577.12 GAM42181.1 - 2.2e-50 171.7 0.2 2.3e-41 142.0 0.0 2.7 3 0 0 3 3 3 2 Serine carboxypeptidase S28 ASFV_J13L PF05568.11 GAM42181.1 - 0.3 10.8 1.7 0.58 9.9 1.7 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein MFS_1 PF07690.16 GAM42182.1 - 5.2e-30 104.6 71.2 2.6e-26 92.4 45.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42182.1 - 0.076 11.9 45.1 0.67 8.7 19.0 3.0 1 1 0 2 2 2 0 Sugar (and other) transporter Zn_clus PF00172.18 GAM42183.1 - 1.9e-08 34.3 12.7 4.4e-08 33.1 12.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM42183.1 - 1.6e-05 24.1 0.1 3.1e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_2 PF07883.11 GAM42184.1 - 7.2e-10 38.4 0.1 4.9e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 GAM42184.1 - 0.004 16.8 0.0 0.0086 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Pyridoxal_deC PF00282.19 GAM42185.1 - 5.1e-104 348.0 0.0 6.2e-104 347.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 GAM42185.1 - 7e-07 28.8 0.0 1.8e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GAM42185.1 - 0.044 12.9 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II MBOAT PF03062.19 GAM42185.1 - 0.12 11.7 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family PNP_UDP_1 PF01048.20 GAM42186.1 - 9.7e-08 31.5 0.0 3.1e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Metallophos PF00149.28 GAM42187.1 - 1.8e-36 126.6 0.1 3.4e-36 125.7 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAM42187.1 - 3.2e-13 49.9 0.7 3.2e-13 49.9 0.7 2.1 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Peptidase_S8 PF00082.22 GAM42188.1 - 1.5e-24 86.8 0.0 2.5e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Glyco_hydro_65N PF03636.15 GAM42190.1 - 8.2e-32 110.7 0.0 1.4e-31 109.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 GAM42190.1 - 7.1e-25 87.7 6.2 5.9e-20 71.5 1.8 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 GAM42190.1 - 0.00032 20.6 0.1 0.0012 18.7 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain F5_F8_type_C PF00754.25 GAM42190.1 - 0.0085 16.2 1.5 0.17 12.0 0.1 3.1 3 0 0 3 3 3 1 F5/8 type C domain SMC_Nse1 PF07574.13 GAM42191.1 - 8.3e-72 241.2 0.2 1.2e-71 240.7 0.2 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 GAM42191.1 - 1.4e-14 54.1 9.4 2.2e-14 53.5 9.4 1.3 1 0 0 1 1 1 1 RING-like domain AbiEi_4 PF13338.6 GAM42191.1 - 0.0021 18.1 0.0 0.0048 17.0 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin zf-RING_2 PF13639.6 GAM42191.1 - 0.0029 17.9 7.9 0.0045 17.3 7.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 GAM42191.1 - 0.0076 16.3 2.3 0.013 15.6 2.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2161 PF09929.9 GAM42191.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) Ribosomal_60s PF00428.19 GAM42191.1 - 0.022 15.3 2.9 0.022 15.3 2.9 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein zf-HC5HC2H_2 PF13832.6 GAM42191.1 - 0.063 13.4 2.2 0.14 12.3 2.2 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GAM42191.1 - 0.58 10.4 6.5 1.6 9.1 6.5 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain Zn_ribbon_17 PF17120.5 GAM42191.1 - 0.69 9.6 3.9 1.2 8.9 3.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 GAM42191.1 - 0.9 9.5 6.8 1.5 8.7 6.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GAM42191.1 - 0.96 9.7 5.3 2.5 8.3 5.3 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain YdjO PF14169.6 GAM42191.1 - 1.2 8.9 4.2 3 7.6 4.2 1.7 1 0 0 1 1 1 0 Cold-inducible protein YdjO FYDLN_acid PF09538.10 GAM42191.1 - 1.6 9.4 7.0 0.13 12.9 1.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C3HC4_2 PF13923.6 GAM42191.1 - 1.7 8.6 6.4 3.1 7.7 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DAO PF01266.24 GAM42192.1 - 9.7e-45 153.7 0.3 1.1e-44 153.5 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM42192.1 - 1.1e-05 24.8 0.0 0.014 14.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM42192.1 - 3e-05 24.5 0.1 0.18 12.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM42192.1 - 0.0098 16.1 0.1 0.024 14.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAM42192.1 - 0.042 13.1 0.0 0.99 8.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 GAM42192.1 - 0.17 11.9 0.7 0.48 10.4 0.0 2.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding adh_short PF00106.25 GAM42193.1 - 4.8e-42 143.6 0.0 5.7e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42193.1 - 9e-27 94.1 0.0 1.1e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM42193.1 - 2.9e-10 40.4 0.0 3.7e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM42193.1 - 0.081 12.4 0.0 0.2 11.1 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CBFD_NFYB_HMF PF00808.23 GAM42194.1 - 2.5e-18 66.1 0.5 6.2e-18 64.9 0.5 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAM42194.1 - 1e-06 29.1 1.0 1.3e-06 28.8 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 SPOB_ab PF14682.6 GAM42194.1 - 0.018 15.1 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Bromo_TP PF07524.13 GAM42194.1 - 0.02 14.9 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated DUF5333 PF17267.2 GAM42194.1 - 0.05 13.8 0.5 0.065 13.4 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5333) Hexokinase_1 PF00349.21 GAM42195.1 - 1.8e-50 171.6 0.0 2.5e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 GAM42195.1 - 1.7e-39 135.7 0.0 6.2e-39 133.9 0.0 1.9 1 1 0 1 1 1 1 Hexokinase DUF1786 PF08735.10 GAM42195.1 - 0.052 12.8 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) DUF3328 PF11807.8 GAM42196.1 - 4.6e-34 118.1 0.1 5.8e-34 117.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.16 GAM42197.1 - 7.8e-36 123.7 31.4 9.7e-36 123.4 31.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Actin PF00022.19 GAM42198.1 - 2.6e-23 82.3 0.0 5.2e-21 74.7 0.0 2.9 3 0 0 3 3 3 2 Actin NAD_binding_6 PF08030.12 GAM42198.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Kin17_mid PF10357.9 GAM42199.1 - 2.9e-49 166.2 3.0 2.9e-49 166.2 3.0 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 GAM42199.1 - 0.013 15.8 2.7 0.03 14.6 2.7 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAM42199.1 - 0.021 15.2 3.6 0.021 15.2 3.6 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GAM42199.1 - 0.083 13.2 0.3 0.083 13.2 0.3 2.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Fasciclin PF02469.22 GAM42200.1 - 2.1e-44 150.8 2.0 5.4e-24 84.8 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain MFS_1 PF07690.16 GAM42201.1 - 7.3e-29 100.8 32.3 1.8e-14 53.5 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAM42201.1 - 2e-06 26.9 12.5 0.00053 19.0 1.6 2.2 1 1 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 GAM42201.1 - 0.00017 20.6 24.7 0.0082 15.0 24.7 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1624 PF07786.12 GAM42201.1 - 0.021 14.4 0.1 0.021 14.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1624) DUF647 PF04884.14 GAM42201.1 - 0.15 11.7 0.1 0.15 11.7 0.1 2.1 3 0 0 3 3 3 0 Vitamin B6 photo-protection and homoeostasis TRI12 PF06609.13 GAM42201.1 - 0.2 10.0 17.4 0.011 14.2 1.1 2.7 3 0 0 3 3 3 0 Fungal trichothecene efflux pump (TRI12) Snf7 PF03357.21 GAM42202.1 - 0.00052 19.7 8.9 0.0007 19.2 8.9 1.2 1 0 0 1 1 1 1 Snf7 DUF4157 PF13699.6 GAM42202.1 - 0.014 15.6 1.5 0.014 15.6 1.5 2.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4157) bZIP_2 PF07716.15 GAM42203.1 - 7.9e-11 41.9 15.9 7.9e-11 41.9 15.9 2.8 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.21 GAM42203.1 - 1.2e-06 28.5 17.2 1.2e-06 28.5 17.2 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 GAM42203.1 - 0.0012 19.3 15.4 0.0012 19.3 15.4 2.1 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF3450 PF11932.8 GAM42203.1 - 0.0045 16.3 5.0 0.0045 16.3 5.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) APG6_N PF17675.1 GAM42203.1 - 0.011 16.3 13.4 0.021 15.3 13.4 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Caps_synth_GfcC PF06251.11 GAM42203.1 - 0.51 9.9 3.3 2 8.0 1.2 2.3 2 0 0 2 2 2 0 Capsule biosynthesis GfcC Bystin PF05291.11 GAM42204.1 - 2.3e-131 437.4 0.0 3.2e-131 437.0 0.0 1.1 1 0 0 1 1 1 1 Bystin Ank_2 PF12796.7 GAM42205.1 - 3.7e-42 142.8 0.0 1.4e-13 51.2 0.0 5.2 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM42205.1 - 4e-34 116.5 0.1 2.2e-09 37.7 0.0 7.5 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM42205.1 - 5.2e-32 106.3 0.3 0.0045 17.4 0.0 9.5 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 GAM42205.1 - 1.9e-27 94.4 7.0 0.01 16.3 0.0 9.9 8 1 1 9 9 9 7 Ankyrin repeat NACHT_N PF17100.5 GAM42205.1 - 1.1e-24 87.6 0.0 2e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_5 PF13857.6 GAM42205.1 - 7.8e-22 77.1 1.4 0.0049 17.2 0.0 8.4 5 3 4 9 9 9 4 Ankyrin repeats (many copies) NACHT PF05729.12 GAM42205.1 - 1.4e-05 25.1 0.0 0.00021 21.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 GAM42205.1 - 8.2e-05 23.1 0.0 0.00032 21.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAM42205.1 - 0.00042 20.6 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AFG1_ATPase PF03969.16 GAM42205.1 - 0.011 14.7 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase AAA_14 PF13173.6 GAM42205.1 - 0.15 12.1 0.2 3.8 7.5 0.2 2.6 1 1 0 1 1 1 0 AAA domain Astro_capsid_p PF12226.8 GAM42205.1 - 9 5.3 13.7 17 4.5 13.7 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Amidase PF01425.21 GAM42207.1 - 3.4e-116 388.9 0.5 4.3e-116 388.5 0.5 1.1 1 0 0 1 1 1 1 Amidase Eno-Rase_NADH_b PF12242.8 GAM42207.1 - 0.21 11.4 1.1 9.4 6.1 0.2 2.9 3 1 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.26 GAM42208.1 - 5.9e-15 55.4 0.0 9.9e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM42208.1 - 0.0048 16.8 0.0 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Metallophos PF00149.28 GAM42209.1 - 6.2e-12 46.5 2.8 7e-12 46.3 1.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 GAM42209.1 - 0.14 12.4 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Transket_pyr PF02779.24 GAM42210.1 - 2.2e-47 161.0 0.0 6.5e-47 159.5 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAM42210.1 - 5.7e-36 123.1 0.1 2e-35 121.4 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain zf-C2H2 PF00096.26 GAM42211.1 - 0.0032 17.8 1.2 0.0068 16.8 1.2 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 GAM42211.1 - 0.0054 17.1 0.3 0.01 16.2 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAM42211.1 - 0.017 15.4 1.9 0.027 14.7 1.9 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF3592 PF12158.8 GAM42211.1 - 0.062 13.4 0.2 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) zf-C2H2_2 PF12756.7 GAM42211.1 - 0.077 13.3 0.2 0.12 12.7 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 GAM42211.1 - 0.079 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 GAM42211.1 - 0.087 13.7 0.5 0.2 12.6 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3449 PF11931.8 GAM42211.1 - 0.22 11.3 0.9 3.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) DUF1691 PF07950.11 GAM42212.1 - 2.8e-39 134.2 4.2 5.7e-30 104.2 1.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) DUF2637 PF10935.8 GAM42212.1 - 0.29 11.0 4.1 0.43 10.5 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2637) TRM PF02005.16 GAM42213.1 - 1.3e-114 383.3 0.0 2.4e-100 336.4 0.0 2.1 1 1 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 GAM42213.1 - 1.2e-07 31.7 0.0 2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DUF2067 PF09840.9 GAM42213.1 - 0.00043 19.9 0.0 0.00092 18.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) PrmA PF06325.13 GAM42213.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Abhydrolase_6 PF12697.7 GAM42214.1 - 2.2e-20 74.2 0.0 2.6e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3786 PF12654.7 GAM42214.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Abhydrolase_5 PF12695.7 GAM42214.1 - 0.098 12.4 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.25 GAM42215.1 - 1.7e-24 86.4 0.0 2e-23 82.9 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42215.1 - 1.4e-17 64.1 0.0 7.7e-17 61.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM42215.1 - 6e-06 26.3 0.2 1.8e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 KR domain Ank_2 PF12796.7 GAM42216.1 - 1e-40 138.2 0.4 3.6e-17 62.7 0.0 4.1 4 1 2 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM42216.1 - 5.2e-21 72.5 0.1 9.4e-05 22.5 0.0 6.4 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 GAM42216.1 - 4.9e-20 71.0 0.0 4.8e-05 23.6 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 GAM42216.1 - 1.6e-17 63.7 0.0 7.7e-09 35.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM42216.1 - 1.6e-17 63.3 0.1 7.3e-07 29.3 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) NACHT PF05729.12 GAM42216.1 - 5.5e-06 26.4 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAM42216.1 - 0.00012 22.5 0.0 0.00044 20.7 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain PNP_UDP_1 PF01048.20 GAM42216.1 - 0.00015 21.1 0.0 0.00025 20.4 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.6 GAM42216.1 - 0.0013 19.0 0.0 0.004 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain FAS_I_H PF18314.1 GAM42217.1 - 9.6e-76 253.9 0.0 2.1e-75 252.8 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 GAM42217.1 - 5.1e-63 212.3 0.0 1.1e-62 211.2 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 GAM42217.1 - 2.7e-22 79.6 0.0 5e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 GAM42217.1 - 1.4e-19 70.3 0.0 3.1e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 GAM42217.1 - 4.9e-11 42.7 0.0 1.6e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 GAM42217.1 - 1.1e-06 28.3 0.0 2.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM42217.1 - 0.0026 17.7 0.0 0.0084 16.0 0.0 1.9 1 0 0 1 1 1 1 KR domain DUF1729 PF08354.10 GAM42218.1 - 1.2e-159 531.0 0.0 1.7e-159 530.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 GAM42218.1 - 2e-91 306.8 0.0 5.2e-90 302.2 0.0 2.5 2 0 0 2 2 2 1 Acyl transferase domain FAS_meander PF17951.1 GAM42218.1 - 2.3e-53 179.9 0.2 9.3e-53 178.0 0.0 2.1 2 0 0 2 2 2 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 GAM42218.1 - 1.5e-39 136.2 0.0 3.7e-39 134.9 0.0 1.7 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 GAM42218.1 - 1.4e-38 131.8 0.0 4.8e-38 130.1 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 GAM42218.1 - 4.3e-38 129.6 0.0 9.8e-38 128.5 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 GAM42218.1 - 3.5e-21 75.7 0.0 9.6e-21 74.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase MCRS_N PF13325.6 GAM42218.1 - 0.042 13.9 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein TFIIF_alpha PF05793.12 GAM42219.1 - 1.7e-05 23.6 15.2 1.7e-05 23.6 15.2 3.3 1 1 3 4 4 4 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF383 PF04063.14 GAM42221.1 - 2.8e-68 229.3 0.2 2.7e-67 226.1 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 GAM42221.1 - 1.7e-19 69.4 1.5 1.7e-19 69.4 1.5 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF384) HEAT PF02985.22 GAM42221.1 - 0.027 14.7 0.0 0.33 11.3 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat IBR PF01485.21 GAM42222.1 - 4e-15 55.8 33.8 1.3e-07 31.7 10.3 2.4 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain DUF2158 PF09926.9 GAM42222.1 - 0.0018 17.9 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized small protein (DUF2158) Inositol_P PF00459.25 GAM42223.1 - 2.3e-61 207.7 0.0 4.4e-61 206.8 0.0 1.4 1 0 0 1 1 1 1 Inositol monophosphatase family DUF676 PF05057.14 GAM42223.1 - 8.9e-41 139.8 0.0 4.3e-39 134.3 0.0 2.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 GAM42223.1 - 0.17 11.7 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) His_Phos_2 PF00328.22 GAM42224.1 - 5.3e-113 378.2 0.1 7.2e-113 377.8 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 GAM42224.1 - 8e-38 128.5 0.0 1.7e-37 127.4 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 GAM42224.1 - 9.5e-06 25.3 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.12 GAM42225.1 - 2.3e-69 233.4 0.0 3.6e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 GAM42225.1 - 4.6e-16 58.9 0.1 0.0082 16.4 0.0 6.4 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAM42225.1 - 1.8e-13 50.7 20.7 3.4e-05 24.5 0.4 10.5 9 1 0 9 9 9 2 WD domain, G-beta repeat PALB2_WD40 PF16756.5 GAM42225.1 - 0.0045 16.0 0.4 0.48 9.3 0.0 3.5 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain eIF2A PF08662.11 GAM42225.1 - 0.037 13.9 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A XPG_I_2 PF12813.7 GAM42226.1 - 2e-86 289.5 0.0 2.6e-86 289.2 0.0 1.1 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 GAM42226.1 - 3.4e-05 24.1 0.0 8.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region Fcf1 PF04900.12 GAM42227.1 - 3.6e-38 129.9 0.4 6.8e-38 129.1 0.4 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 GAM42227.1 - 1.8e-12 47.6 0.8 4.8e-12 46.2 0.1 1.8 2 0 0 2 2 2 1 PIN like domain Tma16 PF11176.8 GAM42227.1 - 0.1 12.4 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Translation machinery-associated protein 16 Ank_2 PF12796.7 GAM42228.1 - 3.4e-26 91.6 0.1 2e-14 53.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM42228.1 - 8e-25 86.9 6.9 4e-10 40.0 0.4 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM42228.1 - 5.2e-23 78.6 1.0 8.7e-05 22.7 0.1 5.1 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 GAM42228.1 - 7.2e-21 73.7 6.3 5.7e-07 29.7 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAM42228.1 - 7.3e-15 54.8 4.9 0.00031 21.0 0.2 4.6 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Lipase_GDSL_2 PF13472.6 GAM42228.1 - 8.5e-15 55.6 7.0 1.6e-12 48.2 0.8 3.2 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAM42228.1 - 3.8e-13 49.9 1.6 2.4e-09 37.5 0.6 2.3 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 GAM42228.1 - 0.00051 20.2 0.6 0.0011 19.1 0.2 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Phage_sheath_1C PF17482.2 GAM42228.1 - 0.0037 17.2 1.5 0.016 15.2 1.5 2.0 1 0 0 1 1 1 1 Phage tail sheath C-terminal domain Asp PF00026.23 GAM42229.1 - 2.1e-18 66.9 0.0 2.8e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease BTB PF00651.31 GAM42229.1 - 5.3e-05 23.4 0.2 0.00022 21.5 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain Trypan_PARP PF05887.11 GAM42229.1 - 0.011 15.7 2.9 0.019 14.9 2.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PGAP1 PF07819.13 GAM42230.1 - 0.00034 20.4 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAM42230.1 - 0.0012 19.5 0.0 0.0015 19.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF726 PF05277.12 GAM42230.1 - 0.0089 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cutinase PF01083.22 GAM42230.1 - 0.055 13.4 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Cutinase DUF676 PF05057.14 GAM42230.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 GAM42230.1 - 0.071 12.4 0.0 0.34 10.2 0.0 1.8 1 1 1 2 2 2 0 Serine aminopeptidase, S33 DUF2333 PF10095.9 GAM42230.1 - 0.089 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Lipase_3 PF01764.25 GAM42230.1 - 0.17 11.8 0.0 0.43 10.4 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) AAA_16 PF13191.6 GAM42231.1 - 0.00078 19.9 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 GAM42231.1 - 0.0029 17.5 0.1 0.0049 16.8 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NACHT PF05729.12 GAM42231.1 - 0.0075 16.2 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 GAM42231.1 - 0.0082 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 GAM42231.1 - 0.019 14.7 0.1 0.056 13.1 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase AAA_18 PF13238.6 GAM42231.1 - 0.033 14.7 0.0 0.086 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAM42231.1 - 0.035 14.3 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAM42231.1 - 0.05 13.9 0.1 0.14 12.5 0.0 1.7 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 GAM42231.1 - 0.054 12.7 0.1 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain Cytidylate_kin PF02224.18 GAM42231.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase RNA_helicase PF00910.22 GAM42231.1 - 0.17 12.3 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PNP_UDP_1 PF01048.20 GAM42232.1 - 4.9e-13 48.9 0.0 9.4e-13 48.0 0.0 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 GAM42233.1 - 4.8e-15 55.9 0.0 3.9e-10 40.2 0.0 3.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM42233.1 - 5.5e-10 39.6 0.9 4.2e-06 27.2 0.1 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) NACHT PF05729.12 GAM42233.1 - 1.1e-08 35.1 0.1 2.6e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 GAM42233.1 - 1.2e-06 28.7 1.0 0.00027 21.2 0.1 4.1 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM42233.1 - 2.4e-06 27.5 0.0 0.17 12.6 0.0 4.8 5 0 0 5 5 4 1 Ankyrin repeat Ank PF00023.30 GAM42233.1 - 1.3e-05 25.4 0.1 0.0025 18.2 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat RNA_helicase PF00910.22 GAM42233.1 - 0.0013 19.1 0.1 0.0038 17.6 0.1 1.8 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 GAM42233.1 - 0.0022 18.4 0.0 0.0066 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM42233.1 - 0.0037 17.5 0.8 0.028 14.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 GAM42233.1 - 0.017 15.0 0.2 0.05 13.5 0.2 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 GAM42233.1 - 0.021 14.0 0.0 0.053 12.7 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 GAM42233.1 - 0.043 13.5 0.1 0.089 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 GAM42233.1 - 0.054 13.9 0.0 0.17 12.3 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rbsn PF11464.8 GAM42233.1 - 0.071 12.9 1.8 0.14 11.9 0.5 2.2 2 0 0 2 2 2 0 Rabenosyn Rab binding domain Ploopntkinase3 PF18751.1 GAM42233.1 - 0.14 12.1 0.0 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 GAM42233.1 - 0.16 12.3 0.0 0.43 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNase_H PF00075.24 GAM42235.1 - 3.4e-05 24.1 0.0 7.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 GAM42235.1 - 0.099 12.5 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 Reverse transcriptase-like Asp PF00026.23 GAM42238.1 - 9e-18 64.7 1.7 1.2e-17 64.3 1.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Ank_2 PF12796.7 GAM42241.1 - 5.9e-11 42.8 0.1 2.1e-10 41.0 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM42241.1 - 5.4e-07 29.8 0.6 0.0053 17.1 0.5 3.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM42241.1 - 3.4e-06 27.0 0.0 0.0086 16.5 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 GAM42241.1 - 1.4e-05 25.3 0.2 0.11 13.0 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 GAM42241.1 - 0.0002 21.8 0.2 0.0021 18.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DYW_deaminase PF14432.6 GAM42241.1 - 0.058 13.3 0.8 2.3 8.1 0.0 3.4 3 0 0 3 3 3 0 DYW family of nucleic acid deaminases TolA_bind_tri PF16331.5 GAM42241.1 - 0.13 12.4 2.5 9.7 6.4 0.0 3.3 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF2677 PF10838.8 GAM42241.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2677) Lipase_GDSL_2 PF13472.6 GAM42242.1 - 1.3e-11 45.2 1.4 2.1e-10 41.3 1.0 2.3 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAM42242.1 - 1.6e-05 25.0 1.3 1.6e-05 25.0 1.3 1.8 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 GAM42242.1 - 0.054 12.7 0.8 0.1 11.8 0.8 1.4 1 0 0 1 1 1 0 OSK domain Myb_DNA-binding PF00249.31 GAM42243.1 - 0.036 14.3 0.1 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Peptidase_S15 PF02129.18 GAM42244.1 - 2.8e-38 132.1 3.7 1.3e-36 126.6 1.7 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 GAM42244.1 - 4.1e-25 89.0 0.0 6.7e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain p450 PF00067.22 GAM42245.1 - 1.6e-67 228.3 0.0 2e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 GAM42246.1 - 1e-19 71.1 0.0 9.8e-11 41.5 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAM42246.1 - 0.002 17.4 0.0 0.031 13.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM42246.1 - 0.0029 17.8 0.4 0.006 16.8 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAM42246.1 - 0.15 10.7 0.2 0.29 9.8 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans PF04082.18 GAM42247.1 - 1.8e-11 43.6 0.0 3.3e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM42247.1 - 4.5e-05 23.5 15.4 0.0001 22.3 15.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BDM PF10684.9 GAM42247.1 - 0.12 12.7 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein FMO-like PF00743.19 GAM42248.1 - 9.7e-16 57.3 0.1 5.8e-15 54.7 0.2 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 GAM42248.1 - 1.2e-14 54.3 0.0 7.2e-12 45.4 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Lactamase_B_2 PF12706.7 GAM42248.1 - 1.5e-07 31.2 0.1 2.9e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAM42248.1 - 5.5e-07 29.8 0.2 1.3e-06 28.6 0.2 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Pyr_redox_2 PF07992.14 GAM42248.1 - 3.8e-06 26.4 0.0 0.00077 18.8 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM42248.1 - 0.00033 19.9 0.0 0.0071 15.5 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAM42248.1 - 0.00081 18.7 0.0 0.011 15.0 0.0 2.6 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B_3 PF13483.6 GAM42248.1 - 0.0053 16.7 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain NAD_binding_9 PF13454.6 GAM42248.1 - 0.051 13.6 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GAM42248.1 - 0.2 10.9 0.0 0.39 9.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Abhydrolase_6 PF12697.7 GAM42249.1 - 2.9e-17 64.0 0.0 3.4e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 GAM42249.1 - 0.04 13.5 0.0 0.088 12.4 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase p450 PF00067.22 GAM42250.1 - 5.1e-70 236.5 0.0 8.4e-70 235.8 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Mst1_SARAH PF11629.8 GAM42250.1 - 0.036 14.1 0.9 7.9 6.7 0.2 3.4 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 FAD_binding_3 PF01494.19 GAM42251.1 - 2.8e-14 53.2 0.1 4.5e-07 29.4 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAM42251.1 - 0.0034 16.7 1.0 0.048 12.9 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM42251.1 - 0.043 14.1 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-CHCC PF10276.9 GAM42251.1 - 0.045 13.8 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger domain Gp_UL130 PF11668.8 GAM42251.1 - 0.16 11.9 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 HCMV glycoprotein pUL130 DAO PF01266.24 GAM42251.1 - 0.24 11.0 0.7 0.82 9.2 0.1 2.1 2 1 1 3 3 3 0 FAD dependent oxidoreductase Abhydrolase_6 PF12697.7 GAM42252.1 - 8.6e-15 55.9 0.4 1.1e-14 55.6 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 GAM42252.1 - 1.2e-12 47.2 0.6 1.9e-10 39.9 0.2 2.8 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 GAM42252.1 - 1.4e-12 47.4 0.1 3.8e-12 46.0 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM42252.1 - 5.3e-10 39.4 0.2 3.2e-08 33.6 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM42252.1 - 5.9e-10 39.0 0.2 6.7e-07 29.0 0.2 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GAM42252.1 - 4.7e-08 32.9 0.1 2.2e-07 30.7 0.1 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 GAM42252.1 - 2.9e-07 30.2 0.3 1.4e-05 24.8 0.0 2.8 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 GAM42252.1 - 7.4e-05 22.8 0.0 0.00049 20.1 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1100 PF06500.11 GAM42252.1 - 0.00032 19.6 0.0 0.00069 18.5 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_3 PF07859.13 GAM42252.1 - 0.005 16.7 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Adeno_PX PF05829.12 GAM42252.1 - 0.052 13.4 0.4 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 Adenovirus late L2 mu core protein (Protein X) Exo_endo_phos_2 PF14529.6 GAM42253.1 - 5.2e-21 74.7 0.1 1.3e-20 73.4 0.1 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 GAM42253.1 - 9.3e-17 61.3 0.0 3.5e-16 59.4 0.0 2.0 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 GAM42253.1 - 6.3e-13 49.1 0.0 1.3e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.23 GAM42253.1 - 5.3e-05 22.9 0.2 0.00015 21.4 0.1 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Sfi1_C PF10638.9 GAM42253.1 - 0.049 14.4 0.5 0.19 12.5 0.1 2.2 2 0 0 2 2 2 0 Spindle body associated protein C-terminus Helo_like_N PF17111.5 GAM42254.1 - 2.5e-20 72.7 5.1 3.5e-20 72.3 5.1 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins UPF0231 PF06062.11 GAM42254.1 - 0.43 10.9 3.3 4.1 7.7 0.8 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) Exo_endo_phos_2 PF14529.6 GAM42255.1 - 1e-17 64.1 0.4 4e-17 62.1 0.4 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 GAM42255.1 - 9.2e-11 42.1 0.0 2.7e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.27 GAM42255.1 - 0.00028 20.5 0.0 0.00085 18.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.16 GAM42257.1 - 4.2e-31 108.1 48.6 1.5e-30 106.3 44.5 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42257.1 - 5.7e-12 45.2 11.2 5.7e-12 45.2 11.2 2.6 2 0 0 2 2 2 1 Sugar (and other) transporter Ntox22 PF15527.6 GAM42257.1 - 0.074 13.1 5.1 0.52 10.4 1.3 3.0 1 1 1 2 2 2 0 Bacterial toxin 22 BLM10_mid PF16507.5 GAM42257.1 - 0.19 10.3 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, mid region ketoacyl-synt PF00109.26 GAM42258.1 - 5.4e-71 239.1 0.0 9.7e-71 238.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 GAM42258.1 - 1.1e-62 212.0 0.0 1.6e-62 211.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 GAM42258.1 - 1.2e-57 194.7 0.1 1.1e-56 191.6 0.1 2.6 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 GAM42258.1 - 5.2e-49 167.5 0.0 9.7e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM42258.1 - 8.9e-35 119.3 0.5 3.1e-34 117.5 0.5 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAM42258.1 - 5.2e-17 62.3 0.0 1.3e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 GAM42258.1 - 1.2e-08 34.6 0.1 3e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 GAM42258.1 - 1.7e-05 24.3 0.4 7.9e-05 22.1 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain PP-binding PF00550.25 GAM42258.1 - 0.0029 17.9 0.0 0.0091 16.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Pyr_redox_3 PF13738.6 GAM42259.1 - 1.2e-13 51.0 0.0 9.9e-13 48.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAM42259.1 - 5.2e-10 38.4 0.0 0.0013 17.3 0.0 3.1 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAM42259.1 - 1.9e-07 30.5 0.0 4.5e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) adh_short_C2 PF13561.6 GAM42260.1 - 4.3e-51 173.7 2.5 7.4e-51 173.0 2.5 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM42260.1 - 1.1e-47 162.0 0.4 1.7e-47 161.4 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM42260.1 - 4.5e-07 29.9 0.5 8.8e-07 29.0 0.5 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM42260.1 - 2.2e-06 27.3 0.4 0.033 13.7 0.1 3.2 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family DUF3117 PF11314.8 GAM42260.1 - 0.39 10.6 1.6 0.49 10.3 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3117) DUF3237 PF11578.8 GAM42261.1 - 1.3e-28 99.7 0.1 1.5e-28 99.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) FAD_binding_3 PF01494.19 GAM42262.1 - 3.1e-23 82.6 0.0 4.8e-23 82.0 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 GAM42262.1 - 2.3e-06 27.1 0.3 4.8e-06 26.0 0.3 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM42262.1 - 5.1e-05 22.5 3.8 9.8e-05 21.6 3.8 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM42262.1 - 8.9e-05 22.7 1.0 0.00028 21.1 1.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM42262.1 - 0.00019 20.8 4.2 0.0069 15.6 1.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM42262.1 - 0.0003 20.5 0.1 0.00048 19.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase CH_2 PF06294.11 GAM42262.1 - 0.027 14.6 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 CH-like domain in sperm protein Lycopene_cycl PF05834.12 GAM42262.1 - 0.076 12.0 1.4 0.76 8.8 1.4 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 GAM42262.1 - 0.091 12.0 0.4 0.16 11.2 0.4 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 GAM42262.1 - 0.095 12.0 2.5 0.14 11.5 2.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAM42262.1 - 0.31 10.3 0.8 0.56 9.5 0.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAM42262.1 - 0.33 10.0 3.9 0.64 9.0 3.9 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 GAM42262.1 - 0.52 9.0 4.2 0.13 11.0 1.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 GAM42262.1 - 1.3 9.6 4.7 1.2 9.7 1.6 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pro_CA PF00484.19 GAM42263.1 - 4.7e-09 36.7 0.2 1.3e-08 35.3 0.2 1.8 1 1 0 1 1 1 1 Carbonic anhydrase NAD_binding_10 PF13460.6 GAM42264.1 - 2.5e-13 50.3 0.0 4e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM42264.1 - 2.6e-12 46.8 0.0 4.5e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAM42264.1 - 0.013 14.9 0.0 0.042 13.3 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 GAM42264.1 - 0.058 13.3 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 KR domain Peptidase_S49 PF01343.18 GAM42264.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 Pro-kuma_activ PF09286.11 GAM42264.1 - 0.1 12.9 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain 3Beta_HSD PF01073.19 GAM42264.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sulfotransfer_3 PF13469.6 GAM42265.1 - 1e-05 26.1 0.0 4.3e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase family 4HBT_2 PF13279.6 GAM42266.1 - 1.7e-07 31.7 0.0 2.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily zinc_ribbon_9 PF14369.6 GAM42267.1 - 0.41 10.9 3.2 0.71 10.2 3.2 1.4 1 0 0 1 1 1 0 zinc-ribbon Glyco_hydro_88 PF07470.13 GAM42268.1 - 9.2e-84 281.4 3.1 1.4e-83 280.8 3.1 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.16 GAM42268.1 - 1.6e-30 106.2 24.2 2.6e-30 105.6 24.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_127 PF07944.12 GAM42268.1 - 3.4e-05 22.6 0.1 3.4e-05 22.6 0.1 1.6 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 DUF21 PF01595.20 GAM42268.1 - 1.1 8.9 5.1 17 5.1 0.1 3.5 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain Glyco_hydro_38N PF01074.22 GAM42269.1 - 4.8e-81 272.3 0.8 7.2e-81 271.7 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAM42269.1 - 2.1e-52 178.3 0.2 3.3e-52 177.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GAM42269.1 - 2.4e-25 88.5 0.0 5.7e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 GAM42269.1 - 1.2e-09 38.1 0.0 1.5e-08 34.6 0.0 2.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_115 PF15979.5 GAM42270.1 - 3.7e-126 421.1 0.0 5.4e-126 420.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 GAM42270.1 - 4e-44 150.5 0.0 7.3e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Glyco_hydro_67N PF03648.14 GAM42270.1 - 0.0004 20.6 0.0 0.00083 19.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus p450 PF00067.22 GAM42272.1 - 2.1e-59 201.5 0.0 2.8e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_4 PF01063.19 GAM42273.1 - 2e-11 44.2 0.0 2.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV AMP-binding PF00501.28 GAM42274.1 - 7.6e-248 822.0 7.8 1.7e-83 280.5 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 GAM42274.1 - 2.5e-157 524.2 0.1 4.1e-35 121.3 0.0 7.6 5 2 1 6 6 6 6 Condensation domain PP-binding PF00550.25 GAM42274.1 - 6.8e-42 141.7 7.9 4.3e-10 39.8 0.2 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAM42274.1 - 1.1e-10 42.4 0.0 0.074 14.0 0.0 4.5 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain OAD_beta PF03977.13 GAM42274.1 - 1.4e-05 24.2 0.3 0.051 12.6 0.1 2.3 2 0 0 2 2 2 2 Na+-transporting oxaloacetate decarboxylase beta subunit Transferase PF02458.15 GAM42274.1 - 0.066 11.9 0.0 8.3 4.9 0.0 2.8 3 0 0 3 3 3 0 Transferase family Mating_N PF12731.7 GAM42274.1 - 0.077 13.1 0.3 20 5.4 0.1 2.8 2 0 0 2 2 2 0 Mating-type protein beta 1 ABC_membrane PF00664.23 GAM42275.1 - 1.4e-28 100.4 12.8 2.5e-28 99.5 11.1 2.0 1 1 1 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAM42275.1 - 4.4e-25 88.8 0.0 1e-24 87.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GAM42275.1 - 4.4e-06 26.3 0.6 0.019 14.4 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAM42275.1 - 0.00012 22.0 0.0 0.02 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM42275.1 - 0.0014 18.4 0.1 0.0039 16.9 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 GAM42275.1 - 0.0095 16.5 0.2 0.034 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 GAM42275.1 - 0.015 15.4 0.8 0.031 14.4 0.1 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM42275.1 - 0.045 13.6 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase MeaB PF03308.16 GAM42275.1 - 0.048 12.6 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP-synt_ab PF00006.25 GAM42275.1 - 0.055 13.1 0.2 0.24 11.0 0.1 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 GAM42275.1 - 0.058 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_15 PF13175.6 GAM42275.1 - 0.065 12.9 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF2919 PF11143.8 GAM42275.1 - 0.084 13.2 2.6 0.18 12.1 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) DUF87 PF01935.17 GAM42275.1 - 0.12 12.5 0.7 0.27 11.3 0.3 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain AMP-binding PF00501.28 GAM42276.1 - 3.1e-188 625.6 1.4 5.7e-83 278.9 0.1 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 GAM42276.1 - 3.5e-81 273.2 0.0 1.7e-25 89.6 0.0 4.9 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.25 GAM42276.1 - 8.8e-20 70.8 1.1 8.8e-09 35.6 0.0 3.0 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAM42276.1 - 3.8e-05 24.6 0.0 0.73 10.8 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain NTP_transf_9 PF04248.12 GAM42276.1 - 0.11 12.4 0.1 9.2 6.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF427) Ank_5 PF13857.6 GAM42277.1 - 0.0024 18.1 0.5 1.6 9.1 0.1 3.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM42277.1 - 0.048 14.3 0.6 0.36 11.5 0.1 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM42278.1 - 7.8e-21 74.5 0.1 1.6e-05 25.4 0.0 6.3 1 1 5 7 7 7 4 Ankyrin repeats (3 copies) NACHT PF05729.12 GAM42278.1 - 1.8e-10 40.9 0.0 3.7e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 GAM42278.1 - 6.5e-09 35.9 0.0 0.0008 19.7 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 GAM42278.1 - 7.9e-09 36.1 0.0 3.8e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Ank PF00023.30 GAM42278.1 - 7.3e-07 29.4 0.0 0.052 14.0 0.0 7.4 9 1 0 9 9 8 1 Ankyrin repeat Ank_3 PF13606.6 GAM42278.1 - 1.7e-06 27.9 0.0 4.7 8.1 0.0 6.0 6 0 0 6 6 4 1 Ankyrin repeat AAA_22 PF13401.6 GAM42278.1 - 5.8e-05 23.4 0.0 0.00026 21.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain Ank_4 PF13637.6 GAM42278.1 - 0.00023 21.7 0.0 0.037 14.6 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) AAA PF00004.29 GAM42278.1 - 0.0014 19.1 0.0 0.015 15.7 0.0 2.8 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAM42278.1 - 0.0016 18.6 0.0 0.0059 16.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 GAM42278.1 - 0.0062 16.9 0.1 0.21 12.0 0.0 2.9 2 0 0 2 2 2 1 RNA helicase SseB_C PF14581.6 GAM42278.1 - 0.023 14.8 0.7 16 5.7 0.0 3.6 1 1 2 3 3 3 0 SseB protein C-terminal domain AAA_14 PF13173.6 GAM42278.1 - 0.028 14.4 0.2 1.9 8.5 0.1 2.9 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 GAM42278.1 - 0.031 14.2 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Torsin PF06309.11 GAM42278.1 - 0.14 12.2 0.0 1.1 9.3 0.0 2.5 2 1 0 2 2 2 0 Torsin Omega_Repress PF07764.11 GAM42278.1 - 0.22 12.1 7.7 16 6.1 0.1 4.8 3 1 2 5 5 5 0 Omega Transcriptional Repressor CW_7 PF08230.11 GAM42278.1 - 0.36 10.6 12.0 3.9 7.3 0.3 4.2 4 1 1 5 5 5 0 CW_7 repeat YDG PF18657.1 GAM42278.1 - 1 9.6 5.0 2.1 8.6 0.1 3.3 1 1 3 4 4 4 0 YDG domain Ank_2 PF12796.7 GAM42280.1 - 1.2e-11 45.0 0.0 0.011 16.3 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM42280.1 - 3.1e-11 42.4 5.8 0.018 15.5 0.0 6.7 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 GAM42280.1 - 1.9e-10 41.0 0.4 0.26 11.9 0.0 5.8 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 GAM42280.1 - 3.9e-07 30.2 0.1 3.5 8.2 0.0 5.3 5 1 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 GAM42280.1 - 9.6e-06 25.8 3.3 0.056 13.8 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Trypan_PARP PF05887.11 GAM42281.1 - 0.0026 17.7 19.4 0.0056 16.7 19.4 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) AT_hook PF02178.19 GAM42281.1 - 0.094 12.6 6.9 0.35 10.9 6.9 2.1 1 0 0 1 1 1 0 AT hook motif Rrn6 PF10214.9 GAM42281.1 - 0.13 10.8 16.6 0.017 13.7 1.7 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor RNase_H2_suC PF08615.11 GAM42281.1 - 0.96 9.6 6.5 0.064 13.4 0.9 1.9 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DDHD PF02862.17 GAM42281.1 - 1.3 9.1 12.1 2.8 8.0 3.2 2.4 2 0 0 2 2 2 0 DDHD domain Spt20 PF12090.8 GAM42281.1 - 3.2 7.3 37.0 0.27 10.8 19.3 2.3 2 0 0 2 2 2 0 Spt20 family DsrC PF04358.13 GAM42281.1 - 6.3 7.4 9.7 32 5.1 0.9 3.3 3 1 0 3 3 3 0 DsrC like protein Gti1_Pac2 PF09729.9 GAM42281.1 - 9.3 6.3 11.3 8 6.5 2.8 2.5 2 0 0 2 2 2 0 Gti1/Pac2 family Glyco_hydro_32N PF00251.20 GAM42282.1 - 1.1e-49 169.6 0.0 1.8e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 GAM42282.1 - 4.8e-17 62.4 0.0 7e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.6 GAM42282.1 - 0.0022 17.3 0.1 0.42 9.9 0.2 3.1 2 1 1 3 3 3 2 BNR repeat-like domain BNR PF02012.20 GAM42282.1 - 1.9 8.8 5.8 1.2 9.4 0.3 2.8 2 0 0 2 2 2 0 BNR/Asp-box repeat DUF2961 PF11175.8 GAM42283.1 - 6.9e-87 291.0 3.7 8.7e-87 290.6 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) Sugar_tr PF00083.24 GAM42284.1 - 4.9e-73 246.5 20.0 6.1e-73 246.2 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM42284.1 - 1.7e-18 66.7 25.8 1.7e-18 66.7 25.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM42284.1 - 2.7e-05 22.8 0.9 4.2e-05 22.2 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4815 PF16075.5 GAM42284.1 - 0.15 10.3 0.0 0.21 9.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4815) DUF4383 PF14325.6 GAM42284.1 - 0.37 11.1 11.5 0.51 10.6 8.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4383) Glyco_hydro_32N PF00251.20 GAM42285.1 - 5.9e-156 518.7 12.3 5.2e-69 233.1 0.4 3.2 3 0 0 3 3 3 3 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 GAM42285.1 - 3.9e-51 173.2 5.7 1e-33 116.6 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 C terminal CDC48_2 PF02933.17 GAM42285.1 - 0.12 12.2 0.0 0.75 9.6 0.0 2.3 1 1 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 HET PF06985.11 GAM42286.1 - 1.2e-09 38.7 0.4 4.2e-08 33.7 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_32N PF00251.20 GAM42287.1 - 6.9e-75 252.4 0.3 8.3e-75 252.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 GAM42287.1 - 4.2e-25 88.6 0.1 6.7e-25 87.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.20 GAM42287.1 - 0.052 13.6 0.1 0.49 10.6 0.1 2.9 1 0 0 1 1 1 0 BNR/Asp-box repeat Glyco_hydro_32N PF00251.20 GAM42288.1 - 1.7e-87 293.8 6.9 1.8e-70 237.9 1.7 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 GAM42288.1 - 3.4e-39 134.4 1.3 6.9e-39 133.4 1.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.6 GAM42288.1 - 0.15 11.4 2.8 0.35 10.1 0.7 2.3 2 1 1 3 3 3 0 BNR repeat-like domain Sugar_tr PF00083.24 GAM42289.1 - 3.4e-123 411.9 21.1 4.2e-123 411.6 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM42289.1 - 1.2e-22 80.3 26.8 1.2e-22 80.3 26.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42290.1 - 1.6e-84 284.4 25.2 2e-84 284.1 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM42290.1 - 5.6e-26 91.3 41.9 5.9e-21 74.8 16.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM42290.1 - 0.00012 20.7 2.0 0.00012 20.7 2.0 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) VIT1 PF01988.19 GAM42290.1 - 0.13 12.2 13.8 0.52 10.1 3.5 2.6 2 0 0 2 2 2 0 VIT family HemY_N PF07219.13 GAM42290.1 - 0.45 10.7 4.9 1 9.6 0.3 3.1 2 0 0 2 2 2 0 HemY protein N-terminus Peptidase_S9 PF00326.21 GAM42291.1 - 0.00096 18.7 0.2 0.0023 17.4 0.2 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 GAM42291.1 - 0.0015 18.4 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM42291.1 - 0.0029 18.2 0.3 0.019 15.6 0.2 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 GAM42291.1 - 0.092 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 GAM42291.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) GFO_IDH_MocA PF01408.22 GAM42292.1 - 3.1e-12 47.4 0.0 2.6e-10 41.1 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ABC2_membrane PF01061.24 GAM42293.1 - 5.2e-69 231.9 48.0 1.8e-35 122.2 22.7 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 GAM42293.1 - 2.2e-26 93.0 0.0 2.1e-16 60.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAM42293.1 - 3.6e-23 81.3 9.2 1.4e-21 76.2 0.0 3.4 3 1 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 GAM42293.1 - 1.4e-07 31.0 40.0 0.0003 20.0 20.1 2.9 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 GAM42293.1 - 0.0011 19.4 0.0 0.45 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 GAM42293.1 - 0.0019 17.8 1.0 0.012 15.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAM42293.1 - 0.0023 17.8 0.2 0.036 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM42293.1 - 0.0023 17.6 0.4 1.8 8.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM42293.1 - 0.0038 17.1 0.5 0.33 10.8 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase Orthoreo_P10 PF07204.11 GAM42293.1 - 0.004 17.1 2.4 0.14 12.1 0.1 3.3 3 0 0 3 3 3 1 Orthoreovirus membrane fusion protein p10 AAA_22 PF13401.6 GAM42293.1 - 0.0069 16.7 0.0 2.3 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM42293.1 - 0.0077 16.8 0.0 1.4 9.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 GAM42293.1 - 0.022 14.2 0.1 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain TRAM1 PF08390.11 GAM42293.1 - 0.063 12.9 0.2 0.063 12.9 0.2 2.1 2 0 0 2 2 1 0 TRAM1-like protein AAA_33 PF13671.6 GAM42293.1 - 0.097 12.8 0.2 5.2 7.2 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAM42293.1 - 0.17 12.1 0.7 1.8 8.8 0.6 2.2 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 GAM42293.1 - 1.2 8.4 16.6 3.5 6.8 3.3 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein NmrA PF05368.13 GAM42294.1 - 5.3e-11 42.5 0.0 8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM42294.1 - 0.00013 21.9 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 GAM42294.1 - 0.19 11.6 0.6 3.3 7.6 0.1 2.6 2 1 1 3 3 3 0 KR domain Pec_lyase_C PF00544.19 GAM42295.1 - 0.0015 18.2 0.1 0.0016 18.0 0.1 1.1 1 0 0 1 1 1 1 Pectate lyase Pyr_redox_2 PF07992.14 GAM42296.1 - 7.2e-40 137.1 0.8 9e-40 136.7 0.8 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM42296.1 - 3.7e-13 49.8 1.2 2.1e-10 41.0 0.5 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM42296.1 - 1e-09 38.1 2.9 1.7e-07 30.8 1.2 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM42296.1 - 8.6e-08 31.6 1.8 0.026 13.6 0.0 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein K_oxygenase PF13434.6 GAM42296.1 - 9.6e-05 21.7 2.3 3.6 6.6 0.2 3.9 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 GAM42296.1 - 0.0023 17.6 6.3 0.073 12.6 1.7 3.4 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 GAM42296.1 - 0.0038 16.5 1.2 1.9 7.7 0.1 2.6 3 0 0 3 3 3 2 Thi4 family Semialdhyde_dh PF01118.24 GAM42296.1 - 0.0046 17.4 0.3 0.026 15.0 0.1 2.4 3 1 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain HI0933_like PF03486.14 GAM42296.1 - 0.017 13.9 9.4 0.53 8.9 0.4 3.7 3 1 1 4 4 4 0 HI0933-like protein DUF5130 PF17174.4 GAM42296.1 - 0.02 15.1 0.8 0.06 13.6 0.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5130) Mqo PF06039.15 GAM42296.1 - 0.029 12.9 0.2 0.067 11.7 0.1 1.6 1 1 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) TrkA_N PF02254.18 GAM42296.1 - 0.059 13.6 0.2 7.4 6.9 0.1 2.8 2 1 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.6 GAM42296.1 - 0.1 13.0 0.1 5.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 GAM42296.1 - 0.14 11.0 1.3 9.7 4.9 0.0 3.4 4 0 0 4 4 4 0 Tryptophan halogenase PNP_UDP_1 PF01048.20 GAM42297.1 - 2.1e-13 50.1 0.4 6.5e-13 48.5 0.4 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Ribosomal_60s PF00428.19 GAM42297.1 - 0.076 13.6 0.9 0.076 13.6 0.9 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein FAM176 PF14851.6 GAM42297.1 - 0.1 12.2 1.2 0.18 11.4 1.2 1.3 1 0 0 1 1 1 0 FAM176 family Retinal PF15449.6 GAM42297.1 - 0.15 9.8 0.1 0.19 9.5 0.1 1.0 1 0 0 1 1 1 0 Retinal protein RNase_H PF00075.24 GAM42298.1 - 1.2e-06 28.8 1.6 0.0076 16.4 0.2 2.7 2 1 1 3 3 3 2 RNase H Exo_endo_phos_2 PF14529.6 GAM42299.1 - 1.2e-10 41.3 1.4 1.3e-10 41.1 0.2 1.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Antifungal_prot PF11402.8 GAM42300.1 - 7.5 6.9 10.7 3 8.2 1.6 2.9 3 0 0 3 3 3 0 Antifungal protein p450 PF00067.22 GAM42301.1 - 1.1e-07 31.1 4.2 4.2e-05 22.5 0.0 3.1 2 1 1 3 3 3 3 Cytochrome P450 MFS_1 PF07690.16 GAM42302.1 - 8.4e-30 103.9 86.0 1.5e-24 86.6 48.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42302.1 - 4.1e-08 32.5 34.6 0.00011 21.3 15.6 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 GAM42302.1 - 0.0006 19.2 18.3 0.0006 19.2 18.3 1.6 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB DcpS PF05652.12 GAM42303.1 - 8.3e-34 116.6 0.1 2.1e-33 115.3 0.0 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 GAM42303.1 - 5.7e-29 100.9 0.4 1.1e-28 100.0 0.4 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding NACHT PF05729.12 GAM42304.1 - 3.1e-24 85.8 0.2 5e-24 85.1 0.2 1.3 1 0 0 1 1 1 1 NACHT domain Ses_B PF17046.5 GAM42304.1 - 0.005 16.8 0.1 0.013 15.4 0.1 1.7 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein AAA_19 PF13245.6 GAM42304.1 - 0.0066 16.8 0.0 0.024 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAM42304.1 - 0.022 15.1 0.0 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase ResIII PF04851.15 GAM42304.1 - 0.062 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TsaE PF02367.17 GAM42304.1 - 0.088 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 GAM42304.1 - 0.094 12.5 0.0 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 GAM42306.1 - 1.5e-08 34.8 0.0 2.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pho86 PF11124.8 GAM42306.1 - 0.0019 17.7 0.2 0.0038 16.7 0.2 1.5 1 1 0 1 1 1 1 Inorganic phosphate transporter Pho86 SAM35 PF10806.8 GAM42306.1 - 0.0041 17.4 0.1 1.3 9.3 0.0 2.3 2 0 0 2 2 2 2 SAM35, subunit of SAM coomplex RICTOR_N PF14664.6 GAM42306.1 - 0.059 12.3 0.1 0.084 11.8 0.1 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Acetyltransf_10 PF13673.7 GAM42306.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM42306.1 - 0.15 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM42306.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.24 GAM42307.1 - 1.4e-46 159.3 19.1 3.4e-46 158.1 19.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM42307.1 - 2.3e-19 69.6 28.2 2.3e-19 69.6 28.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CPP1-like PF11833.8 GAM42307.1 - 2 8.0 0.0 2 8.0 0.0 2.8 4 0 0 4 4 4 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Abhydrolase_4 PF08386.10 GAM42308.1 - 1.9e-07 31.1 0.0 5.6e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein RNase_H PF00075.24 GAM42310.1 - 5.5e-10 39.6 0.0 2.2e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 GAM42310.1 - 0.026 15.2 0.4 0.055 14.2 0.4 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Sfi1_C PF10638.9 GAM42310.1 - 0.08 13.7 0.5 0.16 12.7 0.1 1.7 2 0 0 2 2 2 0 Spindle body associated protein C-terminus TPR_10 PF13374.6 GAM42311.1 - 1.2e-114 371.5 18.3 3.5e-12 45.8 0.0 12.9 12 1 1 13 13 13 12 Tetratricopeptide repeat TPR_12 PF13424.6 GAM42311.1 - 7.3e-110 359.4 39.3 2.6e-15 56.4 0.4 10.0 1 1 10 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.6 GAM42311.1 - 1.9e-29 99.5 22.5 0.0037 17.2 0.0 12.6 12 1 1 13 13 12 7 Tetratricopeptide repeat TPR_2 PF07719.17 GAM42311.1 - 4.5e-23 79.4 22.6 0.06 13.5 0.0 12.5 11 1 1 12 12 12 6 Tetratricopeptide repeat TPR_1 PF00515.28 GAM42311.1 - 1.4e-20 72.2 18.0 0.14 12.1 0.1 11.0 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.6 GAM42311.1 - 1e-18 67.7 2.3 0.012 16.3 0.1 10.3 9 3 2 11 11 11 4 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM42311.1 - 5.5e-18 65.4 25.2 1e-06 28.4 8.5 3.4 1 1 1 3 3 3 3 MalT-like TPR region TPR_4 PF07721.14 GAM42311.1 - 6.2e-18 63.5 10.2 0.72 10.7 0.3 10.2 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAM42311.1 - 5.2e-12 46.1 15.9 0.56 10.8 0.0 10.0 5 4 5 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAM42311.1 - 5.9e-12 45.1 10.2 1.6 9.3 0.0 9.9 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM42311.1 - 1.2e-07 31.4 11.4 0.1 12.9 0.0 7.8 8 0 0 8 8 7 1 Tetratricopeptide repeat NB-ARC PF00931.22 GAM42311.1 - 1.3e-06 27.8 0.0 0.022 13.9 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain ANAPC3 PF12895.7 GAM42311.1 - 0.00045 20.4 5.3 10 6.4 0.1 5.9 4 3 1 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 GAM42311.1 - 0.0041 17.8 23.3 50 5.1 0.0 11.0 11 1 1 12 12 11 0 Tetratricopeptide repeat Ses_B PF17046.5 GAM42311.1 - 0.033 14.2 0.3 0.061 13.3 0.3 1.4 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein AAA_16 PF13191.6 GAM42311.1 - 0.085 13.2 0.0 0.72 10.2 0.0 2.5 1 1 0 1 1 1 0 AAA ATPase domain DUF1771 PF08590.10 GAM42311.1 - 0.2 12.0 4.5 2.2 8.7 0.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) CAML PF14963.6 GAM42311.1 - 0.23 11.5 0.1 0.23 11.5 0.1 2.9 2 1 1 3 3 2 0 Calcium signal-modulating cyclophilin ligand TPR_6 PF13174.6 GAM42311.1 - 0.79 10.5 25.2 43 5.0 0.1 9.8 10 1 0 10 10 10 0 Tetratricopeptide repeat RPN6_N PF18055.1 GAM42311.1 - 1 9.7 16.8 15 6.0 0.4 5.4 5 0 0 5 5 5 0 26S proteasome regulatory subunit RPN6 N-terminal domain PPR PF01535.20 GAM42311.1 - 1.1 9.6 11.6 1.3e+02 3.1 0.1 7.5 9 0 0 9 9 8 0 PPR repeat DUF1897 PF09005.10 GAM42311.1 - 5.1 6.7 8.7 59 3.3 0.2 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF1897) AA_permease_2 PF13520.6 GAM42312.1 - 3.1e-81 273.4 32.3 3.8e-81 273.1 32.3 1.1 1 0 0 1 1 1 1 Amino acid permease TPP_enzyme_N PF02776.18 GAM42313.1 - 8.8e-34 116.6 0.0 1.6e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAM42313.1 - 1.9e-18 66.5 0.0 5.6e-18 65.0 0.0 1.8 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 GAM42313.1 - 3.6e-17 62.6 1.2 2.1e-16 60.1 0.0 2.7 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain FAD_binding_3 PF01494.19 GAM42314.1 - 2.8e-63 214.3 0.0 3.8e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Nucleotid_trans PF03407.16 GAM42314.1 - 8.7e-05 22.6 0.2 0.00015 21.8 0.2 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase FAD_binding_2 PF00890.24 GAM42314.1 - 0.0003 20.0 0.2 0.00049 19.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM42314.1 - 0.00041 20.5 0.1 0.00092 19.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAM42314.1 - 0.00041 19.7 0.0 0.0011 18.3 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 GAM42314.1 - 0.0014 18.1 0.1 0.0047 16.3 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM42314.1 - 0.0038 16.5 0.0 0.0064 15.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM42314.1 - 0.0059 16.2 0.2 0.013 15.1 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAM42314.1 - 0.017 14.4 0.1 0.45 9.7 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 GAM42314.1 - 0.045 14.3 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PALP PF00291.25 GAM42314.1 - 0.094 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Alpha-2-MRAP_N PF06400.11 GAM42314.1 - 0.097 12.7 0.1 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, N-terminal domain GIDA PF01134.22 GAM42314.1 - 0.23 10.5 0.1 0.35 9.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Aldo_ket_red PF00248.21 GAM42315.1 - 8.2e-40 136.8 0.0 1.2e-29 103.5 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Ank_4 PF13637.6 GAM42318.1 - 3.9e-66 218.6 18.9 9.6e-11 42.0 0.1 11.1 3 2 9 12 12 12 11 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM42318.1 - 3.3e-64 213.5 13.3 1.5e-14 54.4 0.2 6.9 2 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM42318.1 - 1.7e-45 147.7 9.1 0.0012 19.1 0.0 13.1 12 0 0 12 12 12 9 Ankyrin repeat Ank PF00023.30 GAM42318.1 - 1.5e-43 145.4 23.9 0.0013 19.1 0.1 13.0 13 0 0 13 13 12 10 Ankyrin repeat Ank_5 PF13857.6 GAM42318.1 - 2.9e-38 129.4 11.3 0.00053 20.2 0.0 11.6 3 2 8 11 11 11 10 Ankyrin repeats (many copies) NACHT PF05729.12 GAM42318.1 - 4.3e-06 26.7 0.0 8.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAM42318.1 - 4.6e-05 23.9 0.0 0.00036 21.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF3447 PF11929.8 GAM42318.1 - 5.6e-05 23.0 0.0 11 6.1 0.0 6.4 3 2 5 8 8 6 1 Domain of unknown function (DUF3447) PNP_UDP_1 PF01048.20 GAM42318.1 - 8.5e-05 21.9 0.2 0.0054 16.0 0.0 2.5 2 0 0 2 2 2 1 Phosphorylase superfamily AAA_22 PF13401.6 GAM42318.1 - 0.003 17.8 0.0 0.029 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM42318.1 - 0.08 13.5 0.0 1.5 9.3 0.0 2.8 1 1 0 1 1 1 0 AAA domain DUF4751 PF15942.5 GAM42318.1 - 0.1 12.5 0.2 0.34 10.8 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4751) AAA_14 PF13173.6 GAM42318.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAM42318.1 - 0.15 12.5 0.0 0.95 9.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Inhibitor_I24 PF10465.9 GAM42318.1 - 9.1 6.3 11.7 10 6.1 0.2 4.7 2 2 4 6 6 6 0 PinA peptidase inhibitor VCBS PF13517.6 GAM42321.1 - 2.3e-36 124.1 59.9 8.5e-10 39.1 1.0 6.9 3 2 4 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 GAM42321.1 - 1.7e-25 90.4 3.1 9.9e-13 48.9 0.7 3.2 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAM42321.1 - 1.9e-12 47.6 3.3 4.9e-08 33.2 0.5 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 GAM42321.1 - 1.2e-06 28.1 17.5 0.067 12.6 0.1 7.3 6 2 2 9 9 9 3 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 GAM42321.1 - 6.2e-06 26.2 36.6 0.014 15.5 0.1 7.3 7 0 0 7 7 7 4 FG-GAP repeat Lipase_GDSL_3 PF14606.6 GAM42321.1 - 0.0016 18.6 0.1 0.0042 17.3 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family BBS2_C PF14782.6 GAM42321.1 - 0.016 14.0 0.7 0.3 9.8 0.0 2.6 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal OSK PF17182.4 GAM42321.1 - 0.066 12.4 0.6 0.14 11.3 0.6 1.5 1 0 0 1 1 1 0 OSK domain EF-hand_1 PF00036.32 GAM42321.1 - 1.1 9.0 19.5 0.17 11.5 0.2 5.0 5 0 0 5 5 5 0 EF hand AA_permease_2 PF13520.6 GAM42322.1 - 4.5e-45 154.3 46.2 6.1e-45 153.8 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM42322.1 - 1.4e-21 76.7 36.6 1.4e-21 76.7 36.6 1.8 2 0 0 2 2 2 1 Amino acid permease YpmT PF17431.2 GAM42322.1 - 0.016 15.2 3.4 0.029 14.4 0.7 2.8 2 0 0 2 2 2 0 Uncharacterized YmpT-like p450 PF00067.22 GAM42323.1 - 3.3e-46 158.0 0.0 4.7e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FtsX PF02687.21 GAM42323.1 - 1.5 9.4 11.1 11 6.5 0.0 3.6 3 0 0 3 3 3 0 FtsX-like permease family AC_N PF16214.5 GAM42323.1 - 2.5 7.2 5.6 4 6.5 5.6 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Methyltransf_2 PF00891.18 GAM42324.1 - 7.3e-21 74.4 0.0 1.5e-20 73.4 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_25 PF13649.6 GAM42324.1 - 7.5e-05 23.4 0.0 0.00031 21.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM42324.1 - 0.00071 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain SLT_L PF14718.6 GAM42324.1 - 0.016 15.3 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain TetR_C_27 PF17935.1 GAM42324.1 - 0.025 14.6 0.0 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Methyltransf_12 PF08242.12 GAM42324.1 - 0.098 13.4 0.0 0.56 11.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain CheR PF01739.18 GAM42324.1 - 0.13 11.7 0.0 1.4 8.4 0.0 2.4 2 1 1 3 3 3 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 GAM42324.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ADH_zinc_N PF00107.26 GAM42325.1 - 6.8e-08 32.6 0.1 6e-07 29.5 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM42325.1 - 6.6e-06 27.2 0.0 1.2e-05 26.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM42325.1 - 9.8e-05 22.2 0.0 0.012 15.5 0.0 2.8 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAM42325.1 - 0.00025 20.9 0.0 0.0022 17.9 0.0 2.1 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase 2-Hacid_dh_C PF02826.19 GAM42325.1 - 0.0003 20.2 0.0 0.051 12.9 0.0 2.7 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 GAM42325.1 - 0.0045 16.5 0.0 0.0078 15.7 0.0 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus CNV-Replicase_N PF16688.5 GAM42325.1 - 0.045 14.1 0.0 0.087 13.2 0.0 1.4 1 0 0 1 1 1 0 Replicase polyprotein N-term from Coronavirus nsp1 PP-binding PF00550.25 GAM42326.1 - 8.3e-22 77.3 5.0 1.9e-10 40.9 0.2 3.1 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.6 GAM42326.1 - 2.7e-15 56.4 0.0 4.3e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 GAM42326.1 - 2.3e-12 47.5 0.0 6.9e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain Zn_clus PF00172.18 GAM42327.1 - 9.7e-10 38.4 8.5 9.7e-10 38.4 8.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EDR1 PF14381.6 GAM42327.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Peptidase_M20 PF01546.28 GAM42328.1 - 1.6e-14 54.1 0.0 3.8e-12 46.4 0.0 2.7 2 1 0 2 2 2 2 Peptidase family M20/M25/M40 PNP_UDP_1 PF01048.20 GAM42328.1 - 2.6e-09 36.7 0.0 7.1e-09 35.3 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily M20_dimer PF07687.14 GAM42328.1 - 0.00024 21.0 0.2 0.00079 19.3 0.1 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAM42328.1 - 0.086 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Asp PF00026.23 GAM42329.1 - 1.4e-48 165.9 19.5 3.1e-48 164.8 19.5 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAM42329.1 - 1.6e-06 28.0 0.3 0.00069 19.4 0.3 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 GAM42329.1 - 6.5e-06 26.7 2.6 0.00025 21.6 0.3 2.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 GAM42329.1 - 0.056 14.0 2.7 0.51 10.9 0.1 3.1 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease FAD_binding_3 PF01494.19 GAM42330.1 - 6.9e-30 104.5 0.0 2.8e-29 102.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM42330.1 - 3.6e-08 33.4 0.1 0.00024 20.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM42330.1 - 1.9e-06 27.4 0.0 0.00014 21.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM42330.1 - 1.8e-05 24.9 0.2 5.8e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM42330.1 - 0.00052 19.2 0.1 0.00096 18.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 GAM42330.1 - 0.0015 17.7 0.0 0.051 12.6 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.12 GAM42330.1 - 0.0066 15.6 0.1 0.027 13.5 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 GAM42330.1 - 0.014 15.9 0.0 0.088 13.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAM42330.1 - 0.085 12.1 0.0 0.44 9.8 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 GAM42330.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 GAM42330.1 - 0.15 10.8 0.0 0.53 8.9 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein DUF455 PF04305.14 GAM42331.1 - 7.7e-99 330.2 0.4 9.6e-99 329.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 GAM42331.1 - 2.7e-06 27.2 0.0 6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 GAM42331.1 - 0.00045 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Bac_rhamnosid6H PF17389.2 GAM42332.1 - 1.6e-19 70.4 7.1 9.7e-19 67.8 0.2 2.8 3 0 0 3 3 3 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 GAM42332.1 - 1.6e-11 43.8 0.5 1.6e-11 43.8 0.5 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF608 PF04685.13 GAM42332.1 - 2.8e-06 26.7 1.6 3.8e-06 26.3 1.6 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Trehalase PF01204.18 GAM42332.1 - 1.8e-05 23.8 0.1 2.7e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 GAM42332.1 - 6.7e-05 22.0 0.1 0.00019 20.5 0.1 1.7 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Glyco_hydro_36 PF17167.4 GAM42332.1 - 0.0008 18.2 0.1 0.0019 17.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase 36 superfamily, catalytic domain Sulfotransfer_4 PF17784.1 GAM42332.1 - 0.056 13.3 0.0 0.86 9.4 0.0 2.4 2 0 0 2 2 2 0 Sulfotransferase domain Bac_rhamnosid PF05592.11 GAM42332.1 - 0.064 13.2 0.0 0.35 10.9 0.0 2.0 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Glyco_hydro_63 PF03200.16 GAM42332.1 - 0.066 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain TRI12 PF06609.13 GAM42333.1 - 2.2e-43 148.6 15.5 2.6e-43 148.3 15.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4538 PF15061.6 GAM42333.1 - 0.049 13.4 2.5 0.098 12.4 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) MFS_1 PF07690.16 GAM42333.1 - 1.6 7.6 39.6 0.011 14.7 23.4 2.9 1 1 0 2 2 2 0 Major Facilitator Superfamily DUF1129 PF06570.11 GAM42333.1 - 2.4 7.6 5.8 0.84 9.1 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) TRI12 PF06609.13 GAM42334.1 - 3.8e-23 81.8 2.4 4.3e-23 81.6 2.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 GAM42334.1 - 2.3e-14 53.1 14.6 2.8e-14 52.8 14.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42334.1 - 2.1e-10 40.1 3.4 2.4e-10 39.9 3.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter YrhC PF14143.6 GAM42334.1 - 0.27 11.3 1.4 4.9 7.3 0.5 2.7 2 1 0 2 2 2 0 YrhC-like protein Tetraspanin PF00335.20 GAM42334.1 - 1.4 8.6 4.6 2.5 7.8 4.5 1.6 1 1 0 1 1 1 0 Tetraspanin family Isochorismatase PF00857.20 GAM42338.1 - 6.8e-39 133.8 0.0 8.3e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family AMP-binding PF00501.28 GAM42342.1 - 1.5e-201 669.5 0.0 1.9e-68 231.0 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 GAM42342.1 - 7.2e-139 463.4 10.2 1.4e-32 113.0 0.0 6.2 5 1 0 5 5 5 5 Condensation domain PP-binding PF00550.25 GAM42342.1 - 1e-40 137.9 14.6 6.2e-08 32.9 0.1 6.6 6 0 0 6 6 6 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAM42342.1 - 2.2e-14 54.2 2.1 2.6e-09 37.9 0.6 3.7 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain ABC_membrane PF00664.23 GAM42343.1 - 2.6e-85 286.4 22.6 7e-44 150.5 5.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM42343.1 - 2.2e-64 216.0 0.0 9.7e-31 107.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 GAM42343.1 - 1.2e-16 60.9 3.6 3e-06 26.8 0.2 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 GAM42343.1 - 1.2e-08 34.2 0.2 0.0029 16.5 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 GAM42343.1 - 1.3e-07 32.2 2.5 0.014 15.8 0.4 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 GAM42343.1 - 1.4e-07 31.1 0.0 0.014 15.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 GAM42343.1 - 4.6e-07 30.2 0.1 0.0011 19.2 0.0 2.9 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_22 PF13401.6 GAM42343.1 - 1.1e-06 28.9 0.2 0.32 11.3 0.0 4.3 5 0 0 5 5 5 2 AAA domain RsgA_GTPase PF03193.16 GAM42343.1 - 2.5e-06 27.5 0.0 0.029 14.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 GAM42343.1 - 2.3e-05 24.3 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 GAM42343.1 - 0.00027 21.5 4.0 0.11 13.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 GAM42343.1 - 0.0003 20.2 0.2 0.29 10.4 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin AAA_30 PF13604.6 GAM42343.1 - 0.00031 20.5 1.3 0.27 10.9 0.0 3.5 3 1 0 3 3 3 1 AAA domain G-alpha PF00503.20 GAM42343.1 - 0.0005 19.3 0.0 0.093 11.9 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_21 PF13304.6 GAM42343.1 - 0.00062 19.7 0.3 0.66 9.7 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 GAM42343.1 - 0.0014 18.8 2.9 2.2 8.6 0.1 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.29 GAM42343.1 - 0.0049 17.3 0.6 19 5.7 0.1 3.8 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAM42343.1 - 0.011 15.7 0.0 7.7 6.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 GAM42343.1 - 0.019 15.0 0.0 1.8 8.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3987 PF13148.6 GAM42343.1 - 0.034 13.1 0.0 2.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_25 PF13481.6 GAM42343.1 - 0.042 13.4 0.1 1.7 8.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 GAM42343.1 - 0.043 14.4 0.0 4.9 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAM42343.1 - 0.044 13.9 0.0 6.9 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAM42343.1 - 0.045 13.5 0.0 6.9 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAM42343.1 - 0.054 13.7 0.1 11 6.3 0.1 2.9 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 GAM42343.1 - 0.056 12.4 0.0 7.6 5.3 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain CbiA PF01656.23 GAM42343.1 - 0.074 13.1 0.0 0.72 9.9 0.0 2.5 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MoaE PF02391.17 GAM42343.1 - 0.082 13.2 0.4 13 6.1 0.0 2.7 2 0 0 2 2 2 0 MoaE protein PRK PF00485.18 GAM42343.1 - 0.099 12.4 0.1 8 6.1 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 GAM42343.1 - 0.19 11.3 0.0 19 4.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3325 PF11804.8 GAM42343.1 - 1.2 9.4 9.2 2.2 8.5 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) APH PF01636.23 GAM42344.1 - 1.5e-10 41.4 0.0 1.8e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM42344.1 - 9.1e-06 25.4 0.0 1.6e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 GAM42344.1 - 0.069 12.4 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase ABC2_membrane PF01061.24 GAM42345.1 - 2.2e-85 285.3 54.3 6.4e-44 149.9 18.1 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 GAM42345.1 - 2e-38 132.0 0.0 1.1e-17 64.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAM42345.1 - 5.6e-29 99.9 0.7 5.6e-29 99.9 0.7 4.2 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.6 GAM42345.1 - 2.9e-11 43.8 0.1 6.8e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 GAM42345.1 - 6.5e-07 29.9 0.2 0.0033 17.8 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 GAM42345.1 - 1.1e-05 25.2 0.2 0.001 18.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM42345.1 - 9.2e-05 23.0 0.0 0.015 15.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAM42345.1 - 0.00013 22.0 0.1 0.0053 16.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 GAM42345.1 - 0.0004 19.6 18.3 0.0004 19.6 18.3 2.8 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_33 PF13671.6 GAM42345.1 - 0.00091 19.4 1.6 0.18 11.9 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_29 PF13555.6 GAM42345.1 - 0.0023 17.6 2.3 0.053 13.3 0.1 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_17 PF13207.6 GAM42345.1 - 0.0051 17.2 0.3 0.38 11.2 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 GAM42345.1 - 0.01 16.1 0.3 1.6 9.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 GAM42345.1 - 0.018 14.9 1.1 1.9 8.3 0.2 3.0 3 0 0 3 3 3 0 NACHT domain MMR_HSR1 PF01926.23 GAM42345.1 - 0.034 14.2 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 GAM42345.1 - 0.044 13.2 0.0 1.7 8.0 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 GAM42345.1 - 0.046 13.4 0.3 0.59 9.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 GAM42345.1 - 0.05 13.4 2.9 0.85 9.4 0.0 2.9 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system dNK PF01712.19 GAM42345.1 - 0.057 13.3 0.0 0.66 9.8 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase cobW PF02492.19 GAM42345.1 - 0.085 12.4 1.4 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 GAM42345.1 - 0.12 12.8 0.1 19 5.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 GAM42345.1 - 0.17 11.8 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain BUD22 PF09073.10 GAM42345.1 - 0.24 10.7 0.0 0.24 10.7 0.0 1.5 2 0 0 2 2 1 0 BUD22 SUIM_assoc PF16619.5 GAM42347.1 - 0.13 12.3 0.0 7.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2235 PF09994.9 GAM42348.1 - 2.8e-67 227.1 0.0 5.5e-43 147.4 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2985 PF11204.8 GAM42349.1 - 9.6e-37 125.0 1.8 3.9e-36 123.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DUF981 PF06168.11 GAM42349.1 - 0.0065 16.4 0.3 0.6 10.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF981) MFS_1_like PF12832.7 GAM42349.1 - 0.043 12.7 1.1 0.089 11.6 1.1 1.5 1 1 0 1 1 1 0 MFS_1 like family DUF3035 PF11233.8 GAM42349.1 - 0.076 13.3 0.2 0.12 12.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) LapA_dom PF06305.11 GAM42349.1 - 0.25 11.2 1.2 0.55 10.1 0.2 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Glyco_transf_28 PF03033.20 GAM42350.1 - 4.7e-19 68.8 0.1 2.4e-11 43.9 0.0 2.8 3 0 0 3 3 3 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 GAM42350.1 - 1e-05 24.5 0.0 1.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 GAM42350.1 - 0.00082 19.7 0.0 0.0028 18.0 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 GAM42350.1 - 0.0024 17.9 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_hydro_76 PF03663.14 GAM42351.1 - 2.6e-143 478.0 34.0 3.3e-143 477.7 34.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Ammonium_transp PF00909.21 GAM42352.1 - 9.3e-65 218.9 29.0 5.3e-63 213.1 29.0 2.0 1 1 0 1 1 1 1 Ammonium Transporter Family DUF2374 PF09574.10 GAM42352.1 - 5.1 7.0 8.7 0.25 11.2 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) HLH PF00010.26 GAM42354.1 - 1.3e-13 50.6 0.5 2.3e-13 49.9 0.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SR-25 PF10500.9 GAM42354.1 - 0.0057 16.3 6.0 0.007 16.0 6.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein eIF-4B PF06273.11 GAM42354.1 - 8.7 5.3 11.4 0.28 10.2 5.7 1.3 2 0 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B Glyco_hydro_28 PF00295.17 GAM42355.1 - 2.4e-49 168.2 13.8 3.2e-49 167.8 13.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 TPR_10 PF13374.6 GAM42356.1 - 1.7e-40 135.8 5.4 6.6e-09 35.4 0.0 6.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAM42356.1 - 2e-38 130.6 7.1 1.7e-17 63.5 0.6 4.0 1 1 1 3 3 3 3 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 GAM42356.1 - 1.2e-28 100.0 0.2 9.5e-14 51.2 0.1 3.1 2 2 0 2 2 2 2 Phosphorylase superfamily Ank_2 PF12796.7 GAM42356.1 - 2e-17 63.5 0.2 0.0041 17.7 0.0 7.2 5 2 1 7 7 7 3 Ankyrin repeats (3 copies) TPR_7 PF13176.6 GAM42356.1 - 3e-15 55.1 12.8 0.02 14.9 0.0 6.2 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAM42356.1 - 8.2e-14 50.7 6.1 0.021 14.6 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat LysM PF01476.20 GAM42356.1 - 3.8e-13 49.3 0.9 0.00019 21.4 0.0 5.1 6 0 0 6 6 5 3 LysM domain AAA_16 PF13191.6 GAM42356.1 - 1.2e-11 45.3 0.0 0.00016 22.1 0.0 3.2 2 0 0 2 2 2 2 AAA ATPase domain TPR_14 PF13428.6 GAM42356.1 - 3.1e-08 33.8 8.9 0.39 11.7 0.1 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM42356.1 - 7.2e-07 28.9 7.0 2.2 8.6 0.1 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM42356.1 - 5.7e-05 22.6 2.3 0.00024 20.6 1.3 2.3 1 1 1 2 2 2 2 MalT-like TPR region NB-ARC PF00931.22 GAM42356.1 - 0.0003 20.0 0.0 0.018 14.2 0.0 2.7 2 1 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 GAM42356.1 - 0.00044 20.2 0.0 0.0026 17.7 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea TPR_8 PF13181.6 GAM42356.1 - 0.00076 19.5 5.8 20 5.7 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM42356.1 - 0.002 18.6 5.5 3.2 8.3 0.1 4.3 2 1 1 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.6 GAM42356.1 - 0.014 15.7 0.0 1.3 9.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain TPR_16 PF13432.6 GAM42356.1 - 0.016 15.9 12.0 0.28 11.9 0.8 4.8 4 1 1 5 5 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAM42356.1 - 0.051 14.2 0.0 40 5.2 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_24 PF13479.6 GAM42356.1 - 0.13 12.0 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain CG-1 PF03859.16 GAM42356.1 - 0.17 11.7 0.1 49 3.7 0.0 3.8 2 1 1 3 3 3 0 CG-1 domain TetR_C_34 PF17929.1 GAM42356.1 - 0.22 11.6 0.7 1 9.4 0.2 2.5 3 0 0 3 3 1 0 Tetracyclin repressor-like, C-terminal domain EELM2 PF15863.5 GAM42357.1 - 0.097 12.8 0.2 0.24 11.5 0.1 1.6 2 0 0 2 2 2 0 Extended EGL-27 and MTA1 homology domain Ank_2 PF12796.7 GAM42358.1 - 6.7e-31 106.7 0.1 2.6e-13 50.3 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM42358.1 - 1.9e-26 92.1 1.5 2.9e-11 43.6 0.0 5.8 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAM42358.1 - 9.8e-25 85.9 0.2 1e-05 25.7 0.1 6.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 GAM42358.1 - 3.9e-23 81.2 3.7 1.4e-08 34.8 0.3 6.4 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM42358.1 - 2.6e-20 70.3 0.1 8.4e-05 22.7 0.1 6.6 6 0 0 6 6 6 4 Ankyrin repeat VCBS PF13517.6 GAM42359.1 - 1.4e-28 99.2 58.9 2.9e-11 43.8 3.7 8.8 5 2 5 10 10 10 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 GAM42359.1 - 6.3e-26 91.9 7.1 2.3e-16 60.7 0.7 3.1 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAM42359.1 - 8e-17 61.9 1.7 2.8e-13 50.3 0.1 3.1 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 GAM42359.1 - 5.2e-08 32.5 7.2 0.59 9.5 0.0 6.6 5 1 2 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.6 GAM42359.1 - 0.0026 17.9 0.0 0.0058 16.8 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.23 GAM42359.1 - 0.063 13.4 42.6 0.4 10.9 1.2 7.9 7 0 0 7 7 7 0 FG-GAP repeat Dockerin_1 PF00404.18 GAM42359.1 - 1.1 9.5 16.9 22 5.3 0.0 6.2 7 0 0 7 7 7 0 Dockerin type I domain HATPase_c PF02518.26 GAM42360.1 - 4.4e-28 98.0 0.1 1.1e-27 96.8 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM42360.1 - 8.3e-20 71.0 0.2 3.9e-19 68.9 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAM42360.1 - 1.3e-19 70.0 0.0 5.3e-19 68.0 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 GAM42360.1 - 1.9e-09 38.0 0.0 4.6e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 GAM42360.1 - 2.6e-07 31.3 0.0 7.5e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 GAM42360.1 - 7.5e-06 26.3 0.0 2.1e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 GAM42360.1 - 9.2e-05 21.9 0.0 0.00026 20.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain TPR_1 PF00515.28 GAM42360.1 - 0.0024 17.6 0.4 7 6.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat HATPase_c_3 PF13589.6 GAM42360.1 - 0.023 14.5 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_8 PF13181.6 GAM42360.1 - 0.025 14.8 0.0 0.33 11.3 0.0 2.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAM42360.1 - 0.12 13.1 0.0 48 4.7 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat FAD_binding_3 PF01494.19 GAM42361.1 - 2.7e-15 56.5 0.0 4.8e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 GAM42361.1 - 0.00011 22.2 0.2 0.012 15.7 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAM42361.1 - 0.00018 20.9 0.1 0.068 12.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM42361.1 - 0.00028 19.9 0.1 0.0024 16.8 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 GAM42361.1 - 0.00069 19.8 0.1 0.0018 18.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAM42361.1 - 0.00096 18.5 0.1 0.0016 17.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 GAM42361.1 - 0.012 15.2 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM42361.1 - 0.043 12.9 0.1 0.11 11.5 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 GAM42361.1 - 0.052 14.1 0.1 0.71 10.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HLH PF00010.26 GAM42362.1 - 7.7e-14 51.4 0.9 1.5e-13 50.5 0.9 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SR-25 PF10500.9 GAM42362.1 - 0.01 15.4 4.1 0.013 15.1 4.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NAM-associated PF14303.6 GAM42362.1 - 0.055 14.2 0.4 0.069 13.9 0.4 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Helo_like_N PF17111.5 GAM42363.1 - 7.7e-88 293.3 5.3 4e-80 268.1 0.3 2.3 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins PRESAN PF09687.10 GAM42363.1 - 0.0047 17.5 0.2 0.023 15.3 0.0 2.1 1 1 0 1 1 1 1 Plasmodium RESA N-terminal HbrB PF08539.11 GAM42363.1 - 0.13 12.3 1.3 0.22 11.5 0.1 1.9 2 0 0 2 2 2 0 HbrB-like dCache_1 PF02743.18 GAM42363.1 - 0.44 10.3 2.6 29 4.3 0.0 2.3 2 1 0 2 2 2 0 Cache domain Sirohm_synth_M PF14824.6 GAM42363.1 - 1.5 8.4 6.1 5.5 6.5 0.0 3.3 3 0 0 3 3 3 0 Sirohaem biosynthesis protein central DUF1664 PF07889.12 GAM42363.1 - 4.1 7.5 14.1 10 6.2 1.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CorA PF01544.18 GAM42363.1 - 9.8 5.4 9.6 2.1 7.6 0.9 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein OTT_1508_deam PF14441.6 GAM42364.1 - 3.9e-20 71.6 1.6 7.9e-20 70.6 1.6 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Seadorna_VP7 PF07387.11 GAM42365.1 - 0.16 11.0 0.0 0.17 10.9 0.0 1.0 1 0 0 1 1 1 0 Seadornavirus VP7 UPRTase PF14681.6 GAM42366.1 - 1e-36 126.4 0.2 2.3e-36 125.2 0.1 1.7 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase AAA_17 PF13207.6 GAM42366.1 - 6e-19 68.8 0.0 1.6e-18 67.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain HAD PF12710.7 GAM42366.1 - 1.5e-14 54.8 0.0 3.5e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_33 PF13671.6 GAM42366.1 - 3.4e-05 24.0 0.0 8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAM42366.1 - 0.00014 22.4 0.0 0.00034 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Pribosyltran PF00156.27 GAM42366.1 - 0.00015 21.3 0.6 0.0027 17.3 0.6 2.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain AAA_16 PF13191.6 GAM42366.1 - 0.0026 18.2 0.1 0.0076 16.6 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 GAM42366.1 - 0.0063 15.8 0.0 0.0099 15.1 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain MeaB PF03308.16 GAM42366.1 - 0.026 13.5 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 GAM42366.1 - 0.027 15.0 0.0 0.066 13.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 GAM42366.1 - 0.052 13.8 0.0 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Peptidase_U4 PF03419.13 GAM42366.1 - 0.076 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA HEAT_2 PF13646.6 GAM42367.1 - 1.4e-65 217.6 31.2 2.6e-10 40.6 0.1 9.4 4 3 7 11 11 10 10 HEAT repeats HEAT PF02985.22 GAM42367.1 - 1.6e-38 127.4 15.3 0.44 10.9 0.0 17.6 18 0 0 18 18 17 8 HEAT repeat HEAT_EZ PF13513.6 GAM42367.1 - 1.4e-30 105.3 18.1 0.019 15.5 0.2 14.1 7 5 7 14 14 14 8 HEAT-like repeat Cnd1 PF12717.7 GAM42367.1 - 6.9e-20 71.7 19.8 1.7e-06 28.2 0.6 8.6 3 2 3 6 6 6 5 non-SMC mitotic condensation complex subunit 1 NACHT PF05729.12 GAM42367.1 - 5.9e-15 55.6 0.0 1.7e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Vac14_Fab1_bd PF12755.7 GAM42367.1 - 1e-14 54.9 5.8 2.3 8.9 0.0 11.3 2 2 9 12 12 12 1 Vacuolar 14 Fab1-binding region NLRC4_HD2 PF17776.1 GAM42367.1 - 1.4e-09 38.5 0.4 6.5e-09 36.4 0.1 2.4 2 0 0 2 2 1 1 NLRC4 helical domain HD2 RTP1_C1 PF10363.9 GAM42367.1 - 1.5e-08 34.8 8.5 0.014 15.6 0.4 7.2 1 1 4 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 GAM42367.1 - 9.1e-08 31.6 10.1 0.92 8.6 0.2 6.8 4 3 2 6 6 6 3 Nuclear condensing complex subunits, C-term domain PNP_UDP_1 PF01048.20 GAM42367.1 - 1.6e-07 30.8 0.0 4.6e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily DIRP PF06584.13 GAM42367.1 - 6.5e-06 26.3 7.2 5.2 7.3 0.0 7.0 3 2 2 8 8 8 1 DIRP RasGEF_N_2 PF14663.6 GAM42367.1 - 1.7e-05 25.2 18.7 4.9 7.6 0.2 10.5 6 4 6 12 12 12 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain NB-ARC PF00931.22 GAM42367.1 - 0.00012 21.3 0.0 0.00012 21.3 0.0 3.8 4 1 2 6 6 6 1 NB-ARC domain AAA_22 PF13401.6 GAM42367.1 - 0.0002 21.7 0.4 0.01 16.1 0.0 4.0 3 3 0 3 3 3 1 AAA domain Adeno_E3_14_5 PF04834.12 GAM42367.1 - 0.0011 19.5 9.3 55 4.4 0.1 9.8 10 6 4 14 14 12 0 Early E3 14.5 kDa protein HEAT_PBS PF03130.16 GAM42367.1 - 0.0012 19.3 21.6 42 5.2 0.0 11.1 12 0 0 12 12 10 0 PBS lyase HEAT-like repeat AAA PF00004.29 GAM42367.1 - 0.0026 18.2 0.0 0.02 15.3 0.0 2.7 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) VHS PF00790.19 GAM42367.1 - 0.0036 17.2 19.3 3.1 7.6 0.3 6.8 3 2 3 7 7 7 2 VHS domain AAA_18 PF13238.6 GAM42367.1 - 0.013 16.1 0.0 0.073 13.6 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAM42367.1 - 0.013 15.5 0.0 0.28 11.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 GAM42367.1 - 0.035 14.5 0.1 0.035 14.5 0.1 4.1 4 2 0 4 4 3 0 AAA ATPase domain Viral_helicase1 PF01443.18 GAM42367.1 - 0.04 13.7 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 GAM42367.1 - 0.071 13.5 0.0 0.35 11.3 0.0 2.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAM42367.1 - 0.099 12.5 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.9 GAM42367.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 GAM42367.1 - 0.15 12.1 0.0 0.75 9.8 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_Cyto PF17910.1 GAM42367.1 - 0.2 12.2 11.9 2.8 8.6 0.3 5.8 5 2 0 5 5 5 0 FeoB cytosolic helical domain Josephin PF02099.17 GAM42367.1 - 0.22 11.6 9.6 7.7 6.6 0.1 5.5 4 3 0 4 4 4 0 Josephin CTK3 PF12243.8 GAM42367.1 - 0.26 11.3 15.4 4.9 7.2 0.0 7.6 6 2 4 10 10 9 0 CTD kinase subunit gamma CTK3 SesA PF17107.5 GAM42367.1 - 0.64 10.2 14.1 36 4.6 0.1 5.9 4 1 2 7 7 5 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Band_7_1 PF13421.6 GAM42367.1 - 0.84 9.3 6.8 68 3.1 0.0 5.0 1 1 3 6 6 6 0 SPFH domain-Band 7 family DUF5388 PF17363.2 GAM42367.1 - 3.8 7.8 7.9 18 5.6 0.0 5.0 5 1 1 6 6 3 0 Family of unknown function (DUF5388) Dopey_N PF04118.14 GAM42367.1 - 5.9 5.9 19.1 2.3 7.2 7.9 4.5 1 1 1 3 3 3 0 Dopey, N-terminal F-box PF00646.33 GAM42367.1 - 8.3 6.4 9.6 1.4e+02 2.5 0.0 6.8 10 0 0 10 10 4 0 F-box domain adh_short_C2 PF13561.6 GAM42368.1 - 4.3e-57 193.4 0.7 4.9e-57 193.2 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM42368.1 - 2e-49 167.7 0.1 2.3e-49 167.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM42368.1 - 2.3e-08 34.2 0.1 3.3e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAM42368.1 - 0.032 13.6 0.0 0.094 12.0 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 GAM42368.1 - 0.13 12.1 0.1 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 GAM42368.1 - 0.13 11.7 0.1 0.44 10.0 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DLH PF01738.18 GAM42370.1 - 3.5e-23 82.3 0.1 5.2e-23 81.7 0.1 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 GAM42370.1 - 0.0092 15.7 0.1 0.11 12.2 0.0 2.5 3 1 0 3 3 3 1 alpha/beta hydrolase fold DUF915 PF06028.11 GAM42370.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) BAAT_C PF08840.11 GAM42370.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Aspzincin_M35 PF14521.6 GAM42371.1 - 0.00017 22.2 0.1 0.0018 18.8 0.0 2.4 2 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase Phage_Gp17 PF17549.2 GAM42372.1 - 9.8 6.2 9.5 1.1 9.3 2.2 2.2 2 0 0 2 2 2 0 Gene Product 17 ATG101 PF07855.12 GAM42373.1 - 0.12 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Autophagy-related protein 101 Glyco_hydro_3_C PF01915.22 GAM42374.1 - 1.2e-47 162.5 0.1 1.9e-47 161.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAM42374.1 - 2.3e-28 99.5 0.0 4.6e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM42374.1 - 4.7e-07 29.8 0.0 9.7e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain DDR PF08841.10 GAM42374.1 - 0.056 12.4 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain SnoaL_2 PF12680.7 GAM42375.1 - 2.2e-05 25.0 0.0 3.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 GAM42375.1 - 0.00024 20.9 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase AMP-binding PF00501.28 GAM42376.1 - 1.5e-69 234.7 0.0 2.1e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 GAM42376.1 - 1.3e-60 204.7 0.0 2.8e-60 203.7 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 GAM42376.1 - 2.7e-53 180.4 0.8 4.7e-53 179.6 0.8 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42376.1 - 2.6e-40 138.5 1.0 4.1e-40 137.8 0.4 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM42376.1 - 5.8e-16 58.9 0.6 5.5e-13 49.2 0.3 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 GAM42376.1 - 3.8e-14 52.7 0.0 1.3e-07 31.4 0.0 2.7 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAM42376.1 - 2.1e-11 44.0 0.0 5.6e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 GAM42376.1 - 2.6e-09 36.5 0.0 6.5e-06 25.3 0.0 3.1 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAM42376.1 - 7.5e-08 31.8 0.1 1.4e-05 24.4 0.0 2.7 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.6 GAM42376.1 - 5.9e-07 29.6 0.1 7.5e-06 26.0 0.1 2.8 4 0 0 4 4 4 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAM42376.1 - 1.1e-05 24.8 2.9 0.0049 16.0 0.1 3.1 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAM42376.1 - 0.0067 15.9 0.0 2.7 7.3 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase DFP PF04127.15 GAM42376.1 - 0.01 15.7 0.3 0.034 14.0 0.3 1.8 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Aa_trans PF01490.18 GAM42377.1 - 2.4e-52 178.1 40.2 2.7e-52 177.9 40.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Saf_2TM PF18303.1 GAM42377.1 - 5.7 6.5 11.2 1.3 8.6 0.1 3.5 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain COX2_TM PF02790.15 GAM42377.1 - 7.6 6.8 12.8 0.21 11.7 2.4 3.4 3 1 1 4 4 4 0 Cytochrome C oxidase subunit II, transmembrane domain DUF1080 PF06439.11 GAM42378.1 - 0.00011 22.3 0.2 0.082 13.0 0.0 2.5 2 1 0 2 2 2 2 Domain of Unknown Function (DUF1080) Laminin_G_2 PF02210.24 GAM42378.1 - 0.0063 17.1 0.0 0.49 11.0 0.0 2.4 2 0 0 2 2 2 1 Laminin G domain CBM_4_9 PF02018.17 GAM42378.1 - 0.067 13.5 3.9 2 8.6 0.3 3.3 2 1 1 3 3 3 0 Carbohydrate binding domain Pyr_redox_2 PF07992.14 GAM42380.1 - 4.8e-18 65.4 0.0 1.5e-17 63.8 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM42380.1 - 1.8e-06 27.3 0.3 1.9e-05 23.9 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAM42380.1 - 2.7e-06 26.3 0.0 0.00042 19.1 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAM42380.1 - 7.5e-06 25.4 2.0 0.082 12.1 0.3 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM42380.1 - 0.00064 18.9 10.1 0.017 14.2 0.4 2.7 2 1 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 GAM42380.1 - 0.0017 18.5 0.0 0.0045 17.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GAM42380.1 - 0.0018 17.7 1.4 0.0024 17.3 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 GAM42380.1 - 0.002 17.8 0.1 0.0061 16.2 0.1 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAM42380.1 - 0.0027 17.0 0.0 0.0065 15.7 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 GAM42380.1 - 0.0031 16.8 1.1 0.0061 15.9 0.8 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 GAM42380.1 - 0.0049 16.9 0.1 1.5 8.8 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding DUF4554 PF15091.6 GAM42380.1 - 0.026 13.4 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Lycopene_cycl PF05834.12 GAM42380.1 - 0.039 13.0 0.1 0.089 11.8 0.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.6 GAM42380.1 - 0.06 12.5 0.1 4.4 6.3 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 GAM42380.1 - 0.12 11.6 0.2 1 8.6 0.1 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase SRR1 PF07985.12 GAM42381.1 - 1.1e-08 35.0 0.0 2.2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 SRR1 PNP_UDP_1 PF01048.20 GAM42382.1 - 1.7e-08 34.0 0.0 3e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily adh_short_C2 PF13561.6 GAM42383.1 - 4.5e-55 186.8 0.1 5.7e-55 186.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM42383.1 - 6.2e-44 149.8 0.2 7.7e-44 149.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM42383.1 - 4.3e-14 52.8 0.1 6.3e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM42383.1 - 7.3e-07 28.9 0.1 1.5e-06 27.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM42383.1 - 2.5e-05 23.8 0.0 3.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAM42383.1 - 0.013 14.6 0.2 0.019 14.0 0.2 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Iso_dh PF00180.20 GAM42383.1 - 0.015 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase Pyr_redox_2 PF07992.14 GAM42383.1 - 0.015 14.6 0.2 0.044 13.0 0.1 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 GAM42383.1 - 0.1 11.9 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 GAM42383.1 - 0.11 13.1 0.1 0.25 11.9 0.0 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase HATPase_c PF02518.26 GAM42383.1 - 0.17 12.4 0.0 0.42 11.1 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hva1_TUDOR PF11160.8 GAM42384.1 - 0.0021 18.2 0.5 0.0036 17.5 0.5 1.5 1 1 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Arrestin_N PF00339.29 GAM42385.1 - 0.0012 18.9 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAM42385.1 - 0.094 13.2 0.7 4.2 7.8 0.1 2.7 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain YpzI PF14140.6 GAM42386.1 - 0.0036 17.0 4.2 1.4 8.8 0.2 3.9 4 0 0 4 4 4 2 YpzI-like protein KGG PF10685.9 GAM42387.1 - 1.8e-13 50.3 15.1 3.6e-08 33.4 0.4 3.2 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif RTA1 PF04479.13 GAM42388.1 - 3.6e-57 193.3 9.0 6.1e-57 192.6 9.0 1.4 1 0 0 1 1 1 1 RTA1 like protein Glyco_hydro_30 PF02055.16 GAM42388.1 - 6.2e-35 120.8 8.3 1.6e-34 119.5 8.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 GAM42388.1 - 3.2e-07 30.5 1.9 7.9e-07 29.2 1.9 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 GAM42388.1 - 2.9e-05 23.5 2.7 6.8e-05 22.2 2.7 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Collar PF07484.12 GAM42388.1 - 0.15 12.1 0.7 0.54 10.3 0.2 2.2 2 0 0 2 2 2 0 Phage Tail Collar Domain TRAM_LAG1_CLN8 PF03798.16 GAM42389.1 - 1.1e-29 103.6 13.9 1.1e-29 103.6 13.9 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 GAM42389.1 - 3.6e-22 77.8 0.6 1.2e-21 76.2 0.1 2.2 2 0 0 2 2 2 1 TRAM1-like protein FMO-like PF00743.19 GAM42390.1 - 3.6e-21 75.2 0.0 1.6e-20 73.1 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAM42390.1 - 3.1e-15 56.2 0.0 3.1e-11 43.1 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM42390.1 - 1.8e-09 37.2 0.0 2.3e-06 27.0 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 GAM42390.1 - 3.5e-09 36.3 0.0 1.7e-08 34.0 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM42390.1 - 1.1e-05 25.6 0.4 0.00014 22.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 GAM42390.1 - 1.7e-05 24.2 0.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 GAM42390.1 - 3.7e-05 24.2 1.7 0.22 12.1 0.4 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM42390.1 - 5.9e-05 23.1 0.1 0.059 13.4 0.1 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 GAM42390.1 - 0.00057 20.0 0.0 0.91 9.6 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 GAM42390.1 - 0.0012 18.5 1.3 0.008 15.8 0.3 2.6 4 0 0 4 4 4 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 GAM42390.1 - 0.0024 17.8 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 GAM42390.1 - 0.0063 16.9 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 GAM42390.1 - 0.19 10.4 0.7 1.4 7.5 0.1 2.3 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 GAM42390.1 - 7.6 5.5 5.0 0.88 8.6 0.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A PCI PF01399.27 GAM42391.1 - 0.016 15.7 0.0 1.4 9.5 0.0 2.8 2 0 0 2 2 2 0 PCI domain TPR_2 PF07719.17 GAM42391.1 - 0.23 11.7 3.3 0.79 10.0 3.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 GAM42392.1 - 0.00073 18.9 0.0 0.0017 17.6 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily Acyl_transf_1 PF00698.21 GAM42393.1 - 5.4e-58 197.0 0.0 8.7e-58 196.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 GAM42393.1 - 6e-54 182.7 0.8 4.1e-31 108.3 0.0 2.9 1 1 1 2 2 2 2 KR domain PS-DH PF14765.6 GAM42393.1 - 8.9e-53 179.5 0.0 1.3e-52 178.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 GAM42393.1 - 6e-46 157.1 0.0 1.6e-27 96.7 0.0 2.6 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAM42393.1 - 1.7e-29 102.2 0.0 4e-29 101.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAM42393.1 - 7.5e-22 77.9 0.0 3.2e-21 75.9 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 GAM42393.1 - 3.8e-15 56.0 0.0 1.8e-14 53.9 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM42393.1 - 2.6e-13 51.2 0.0 2.2e-12 48.2 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 GAM42393.1 - 1.2e-09 38.8 0.0 4.3e-09 37.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 GAM42393.1 - 4e-09 36.2 1.5 9.9e-08 31.7 0.2 3.0 2 1 0 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.6 GAM42393.1 - 1e-06 28.6 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM42393.1 - 1.8e-06 28.5 0.0 2.7e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM42393.1 - 1.1e-05 25.3 0.0 3.9e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 GAM42393.1 - 0.0028 17.5 0.3 0.0061 16.4 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 GAM42393.1 - 0.011 15.3 0.1 0.045 13.3 0.1 2.0 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 GAM42393.1 - 0.019 15.3 0.0 0.06 13.7 0.0 2.0 1 0 0 1 1 1 0 Phosphopantetheine attachment site PCMT PF01135.19 GAM42393.1 - 0.097 12.4 0.0 0.62 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) p450 PF00067.22 GAM42394.1 - 3.4e-29 101.9 0.2 2.3e-14 53.0 0.1 2.2 1 1 1 2 2 2 2 Cytochrome P450 DUF3153 PF11353.8 GAM42394.1 - 0.096 12.3 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Zn_clus PF00172.18 GAM42395.1 - 4.8e-07 29.8 7.7 4.8e-07 29.8 7.7 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1776 PF08643.10 GAM42395.1 - 0.0024 17.3 1.2 0.0048 16.3 1.2 1.5 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DIOX_N PF14226.6 GAM42396.1 - 4.1e-26 92.1 0.1 4.9e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.16 GAM42397.1 - 5.9e-25 87.9 77.1 9.6e-21 74.1 40.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1279 PF06916.13 GAM42397.1 - 0.11 13.1 0.5 0.11 13.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) Abhydrolase_3 PF07859.13 GAM42398.1 - 3.1e-30 105.6 0.0 3e-26 92.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 GAM42398.1 - 1.7e-06 27.2 0.7 8.3e-06 24.9 0.7 1.8 1 1 0 1 1 1 1 Carboxylesterase family HTH_Tnp_Tc5 PF03221.16 GAM42400.1 - 1e-14 54.3 0.9 8.9e-14 51.3 0.0 2.6 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 GAM42400.1 - 9.7e-08 31.9 0.1 2.5e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_24 PF13412.6 GAM42400.1 - 0.02 14.4 0.1 0.068 12.7 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding LexA_DNA_bind PF01726.16 GAM42400.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain EHN PF06441.12 GAM42401.1 - 1.3e-27 96.3 0.1 3.7e-27 94.8 0.0 1.8 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 GAM42401.1 - 6.5e-12 45.6 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold bZIP_1 PF00170.21 GAM42402.1 - 6.8e-06 26.1 3.6 1.4e-05 25.1 3.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor TMEM223 PF14640.6 GAM42402.1 - 0.071 13.3 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Transmembrane protein 223 bZIP_Maf PF03131.17 GAM42402.1 - 0.16 12.5 6.7 0.42 11.2 6.7 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor Fungal_trans_2 PF11951.8 GAM42403.1 - 0.0023 16.8 0.2 0.0063 15.4 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ribosomal_L30_N PF08079.12 GAM42403.1 - 0.09 13.0 5.0 0.15 12.4 5.0 1.2 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Epimerase PF01370.21 GAM42405.1 - 5e-23 81.8 0.1 4.9e-22 78.6 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM42405.1 - 1.4e-14 54.3 0.5 2.6e-13 50.1 0.1 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAM42405.1 - 3.2e-08 32.9 0.0 5e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAM42405.1 - 2.3e-06 26.9 0.0 5e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAM42405.1 - 5.3e-06 25.8 0.1 1.7e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 GAM42405.1 - 9.8e-05 22.3 0.0 0.00031 20.7 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAM42405.1 - 0.00086 18.5 0.1 0.0097 15.1 0.1 2.4 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein Sugar_tr PF00083.24 GAM42406.1 - 1.1e-90 304.7 30.3 2.4e-73 247.6 11.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter AMP-binding PF00501.28 GAM42407.1 - 6.1e-64 216.2 0.0 8e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Ribonucleas_3_3 PF14622.6 GAM42408.1 - 1.6e-08 34.7 0.3 4.4e-08 33.3 0.1 1.8 2 0 0 2 2 2 1 Ribonuclease-III-like Condensation PF00668.20 GAM42408.1 - 3.8e-05 22.5 3.0 0.0016 17.2 0.1 2.2 2 0 0 2 2 2 2 Condensation domain Ribonuclease_3 PF00636.26 GAM42408.1 - 4.4e-05 24.0 0.2 0.00034 21.2 0.2 2.3 1 1 0 1 1 1 1 Ribonuclease III domain FAD_binding_3 PF01494.19 GAM42409.1 - 1.3e-76 258.1 0.0 1.7e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 GAM42409.1 - 9.4e-05 21.7 1.9 0.22 10.6 0.3 2.3 1 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAM42409.1 - 0.00056 19.6 0.1 0.41 10.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM42409.1 - 0.0078 16.4 0.8 0.038 14.2 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM42409.1 - 0.018 14.3 0.0 0.16 11.2 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 GAM42410.1 - 2.7e-31 108.9 14.7 3e-31 108.8 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3021 PF11457.8 GAM42410.1 - 0.19 12.1 16.6 0.83 10.0 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) DUF3566 PF12089.8 GAM42410.1 - 0.33 11.3 6.5 0.55 10.6 0.3 2.9 2 1 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) GlpM PF06942.12 GAM42410.1 - 1.3 9.4 7.0 1.5 9.3 1.2 2.4 2 1 0 2 2 2 0 GlpM protein TMIE PF16038.5 GAM42410.1 - 4.1 7.3 5.5 8.1 6.4 0.0 2.9 2 1 1 3 3 3 0 TMIE protein Sugar_tr PF00083.24 GAM42411.1 - 8.6e-71 239.1 27.5 1e-70 238.9 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM42411.1 - 1.1e-18 67.3 57.7 4.3e-16 58.8 33.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 GAM42412.1 - 0.017 14.6 0.0 0.053 13.0 0.0 1.8 2 1 0 2 2 2 0 short chain dehydrogenase GMC_oxred_N PF00732.19 GAM42413.1 - 3.8e-49 167.6 0.0 1.2e-23 83.9 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase ADH_zinc_N PF00107.26 GAM42413.1 - 3e-07 30.5 0.2 5.6e-07 29.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DeoRC PF00455.22 GAM42413.1 - 0.031 14.2 0.1 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain NAD_binding_8 PF13450.6 GAM42415.1 - 1.1e-11 44.8 0.4 2.1e-11 43.9 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAM42415.1 - 2.3e-05 23.9 0.0 0.00031 20.1 0.0 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 GAM42415.1 - 3.3e-05 23.4 0.7 5.7e-05 22.6 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 GAM42415.1 - 0.00024 20.8 2.0 0.024 14.2 1.9 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM42415.1 - 0.0022 17.1 1.1 0.0035 16.5 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 GAM42415.1 - 0.0029 16.4 0.6 0.0046 15.7 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 GAM42415.1 - 0.0031 16.8 0.4 0.0057 15.9 0.4 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAM42415.1 - 0.0033 16.7 0.3 0.0053 16.0 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM42415.1 - 0.017 15.7 0.3 0.05 14.2 0.3 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ferric_reduct PF01794.19 GAM42416.1 - 1.8e-06 28.1 0.5 4.3e-06 26.8 0.5 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Hemerythrin PF01814.23 GAM42416.1 - 1.1e-05 26.1 0.0 1.8e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain adh_short PF00106.25 GAM42418.1 - 1e-12 48.0 0.0 1.4e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42418.1 - 4.7e-10 39.4 0.0 6.2e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAM42418.1 - 0.0025 17.3 0.0 0.0041 16.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAM42418.1 - 0.0047 16.1 0.0 0.007 15.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 GAM42418.1 - 0.026 14.4 0.0 0.11 12.3 0.0 1.9 1 1 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 GAM42418.1 - 0.21 11.0 0.0 0.4 10.0 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 GAM42419.1 - 3.3e-16 59.1 39.5 1.3e-14 53.9 39.5 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42419.1 - 0.0061 15.5 21.0 0.027 13.4 0.3 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter DUF5316 PF17247.2 GAM42419.1 - 0.016 15.2 0.3 0.016 15.2 0.3 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5316) Transferase PF02458.15 GAM42420.1 - 3.4e-22 78.7 0.0 1.7e-19 69.8 0.0 2.1 2 0 0 2 2 2 2 Transferase family ANAPC2 PF08672.11 GAM42420.1 - 0.027 15.0 0.0 0.88 10.1 0.0 2.5 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 MFS_1 PF07690.16 GAM42421.1 - 6.6e-40 137.1 51.8 1.3e-39 136.2 50.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M48_N PF16491.5 GAM42421.1 - 0.53 10.2 6.5 0.092 12.6 1.7 2.2 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices Transferase PF02458.15 GAM42422.1 - 0.00012 20.9 0.0 0.00026 19.8 0.0 1.5 1 0 0 1 1 1 1 Transferase family adh_short PF00106.25 GAM42423.1 - 8.5e-35 120.0 1.7 1e-34 119.8 1.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42423.1 - 3.5e-24 85.7 1.5 9.8e-24 84.2 1.5 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM42423.1 - 5.2e-14 52.6 1.6 7e-14 52.1 1.6 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM42423.1 - 2.9e-11 43.0 0.3 3.7e-11 42.7 0.3 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAM42423.1 - 2.5e-10 40.2 0.3 4.4e-10 39.4 0.3 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM42423.1 - 0.0022 17.4 0.3 0.021 14.2 0.3 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Eno-Rase_NADH_b PF12242.8 GAM42423.1 - 0.044 13.5 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.21 GAM42423.1 - 0.21 10.9 1.4 1.1 8.6 0.2 2.1 2 0 0 2 2 2 0 ThiF family Lactamase_B PF00753.27 GAM42424.1 - 1.8e-15 57.4 3.4 6.7e-14 52.4 3.4 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM42424.1 - 0.0003 20.4 0.4 0.00069 19.2 0.4 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ketoacyl-synt PF00109.26 GAM42425.1 - 1.3e-75 254.2 0.0 3.1e-75 253.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 GAM42425.1 - 2.6e-47 161.6 0.1 4.1e-46 157.6 0.0 2.5 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 GAM42425.1 - 1e-40 140.2 0.0 1.9e-40 139.3 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM42425.1 - 1.4e-34 118.6 2.0 6.5e-34 116.5 0.4 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 GAM42425.1 - 1.4e-10 41.4 0.1 5.6e-10 39.4 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 GAM42425.1 - 4.6e-09 36.7 0.0 1.2e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 GAM42425.1 - 1.1e-08 34.6 0.0 2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 GAM42425.1 - 3.4e-05 23.3 0.1 8.8e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Scytalone_dh PF02982.14 GAM42426.1 - 8.6e-68 227.2 0.2 1e-67 226.9 0.2 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 GAM42426.1 - 2.1e-07 31.1 0.3 2.5e-07 30.9 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain adh_short_C2 PF13561.6 GAM42427.1 - 4e-57 193.5 2.0 5.4e-57 193.0 2.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM42427.1 - 2e-48 164.5 0.9 2.4e-48 164.2 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM42427.1 - 1.7e-11 44.4 0.7 2.2e-11 44.0 0.7 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 GAM42427.1 - 0.0032 16.9 0.8 0.048 13.0 0.2 2.2 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 GAM42427.1 - 0.0051 16.3 0.6 0.032 13.7 0.6 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 GAM42427.1 - 0.034 13.5 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Frtz PF11768.8 GAM42428.1 - 0.006 15.0 0.0 0.009 14.4 0.0 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF505 PF04458.12 GAM42428.1 - 0.11 10.9 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF505) HTH_7 PF02796.15 GAM42428.1 - 0.12 12.4 0.0 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase AflR PF08493.10 GAM42429.1 - 2.1e-15 56.9 3.8 7.3e-15 55.2 3.8 1.8 1 1 0 1 1 1 1 Aflatoxin regulatory protein FAD_binding_3 PF01494.19 GAM42430.1 - 4.5e-12 45.9 0.1 1.6e-11 44.0 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM42430.1 - 1.2e-06 28.4 0.1 0.05 13.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM42430.1 - 5.7e-05 22.5 0.1 0.13 11.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM42430.1 - 0.00017 20.8 0.1 0.0013 17.9 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAM42430.1 - 0.0091 14.7 0.2 0.16 10.7 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 GAM42430.1 - 0.06 12.7 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.25 GAM42431.1 - 1.9e-23 83.0 0.0 8.1e-22 77.6 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42431.1 - 3.5e-13 49.7 0.0 1.2e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM42431.1 - 2.4e-08 34.1 0.1 3.6e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 KR domain AMP-binding PF00501.28 GAM42432.1 - 2.8e-51 174.4 0.0 4e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_10 PF13460.6 GAM42432.1 - 1.6e-13 51.0 0.0 3.2e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM42432.1 - 2.7e-07 30.4 0.0 5.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 GAM42432.1 - 0.066 13.8 0.0 0.29 11.8 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 GAM42432.1 - 0.076 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 GAM42432.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.19 GAM42432.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAM42432.1 - 0.17 11.0 0.0 0.39 9.8 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Questin_oxidase PF14027.6 GAM42433.1 - 1.8e-89 300.6 0.0 2.1e-89 300.4 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like baeRF_family7 PF18849.1 GAM42433.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 p450 PF00067.22 GAM42434.1 - 1.3e-60 205.5 0.0 1.7e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 GAM42435.1 - 3e-31 108.7 0.0 5.8e-31 107.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Cas9-BH PF16593.5 GAM42435.1 - 0.035 13.8 0.1 0.086 12.6 0.1 1.6 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 DUF1972 PF09314.11 GAM42435.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) 5_nucleotid_C PF02872.18 GAM42436.1 - 8.4e-40 136.6 0.0 4.3e-39 134.3 0.0 2.3 3 0 0 3 3 3 1 5'-nucleotidase, C-terminal domain Fungal_trans_2 PF11951.8 GAM42436.1 - 3.3e-07 29.5 0.1 7.9e-07 28.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Metallophos PF00149.28 GAM42436.1 - 4e-05 24.2 0.1 0.0001 22.9 0.1 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zn_clus PF00172.18 GAM42436.1 - 0.0011 19.1 5.0 0.0021 18.1 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIE-A_C PF11521.8 GAM42437.1 - 0.0082 16.4 0.1 0.0082 16.4 0.1 2.3 3 0 0 3 3 3 1 C-terminal general transcription factor TFIIE alpha UPF0731 PF14982.6 GAM42437.1 - 0.036 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 UPF0731 family CbtA PF09490.10 GAM42437.1 - 0.18 11.6 0.6 0.32 10.7 0.6 1.4 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) TRP PF06011.12 GAM42438.1 - 6.3e-154 512.8 33.9 7.6e-154 512.5 33.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 GAM42438.1 - 5.6e-35 120.7 0.6 8.6e-35 120.1 0.6 1.3 1 0 0 1 1 1 1 ML-like domain Choline_sulf_C PF12411.8 GAM42438.1 - 0.098 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal CFEM PF05730.11 GAM42439.1 - 5.8e-15 55.1 9.0 1e-14 54.4 9.0 1.4 1 0 0 1 1 1 1 CFEM domain Ldh_2 PF02615.14 GAM42441.1 - 2.5e-127 424.6 0.3 2.9e-127 424.4 0.3 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Quaking_NLS PF16551.5 GAM42441.1 - 0.047 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative nuclear localisation signal of quaking adh_short_C2 PF13561.6 GAM42442.1 - 5.9e-58 196.2 0.4 7.4e-58 195.9 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM42442.1 - 3.1e-45 154.1 1.2 3.6e-45 153.8 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM42442.1 - 0.00066 19.6 0.2 0.001 19.0 0.2 1.2 1 0 0 1 1 1 1 KR domain SWIRM-assoc_3 PF16498.5 GAM42442.1 - 0.016 15.4 0.6 0.042 14.1 0.6 1.7 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal 4HBT PF03061.22 GAM42443.1 - 4.8e-10 39.6 0.3 8.6e-10 38.8 0.2 1.5 1 1 1 2 2 2 1 Thioesterase superfamily DUF5042 PF16445.5 GAM42443.1 - 0.12 10.7 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5042) ILVD_EDD PF00920.21 GAM42444.1 - 2.2e-150 501.7 0.2 2.5e-150 501.5 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family Dabb PF07876.12 GAM42445.1 - 2.4e-12 47.3 0.4 3.6e-12 46.7 0.4 1.3 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF3198 PF11433.8 GAM42445.1 - 0.007 16.2 0.3 0.012 15.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3198) Fungal_trans PF04082.18 GAM42446.1 - 2.6e-17 62.7 1.9 4.5e-17 62.0 1.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain WBS28 PF15164.6 GAM42446.1 - 0.061 12.6 1.8 0.38 10.0 0.1 2.1 2 0 0 2 2 2 0 Williams-Beuren syndrome chromosomal region 28 protein homologue DUF4188 PF13826.6 GAM42446.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) Abhydrolase_1 PF00561.20 GAM42448.1 - 3.7e-14 53.0 0.0 6.4e-13 48.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM42448.1 - 2.5e-11 43.3 0.0 7.5e-11 41.8 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM42448.1 - 7.2e-06 26.8 0.0 9.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 GAM42448.1 - 3.2e-05 22.8 0.0 8.7e-05 21.3 0.0 1.6 2 0 0 2 2 2 1 Ndr family Peptidase_S9 PF00326.21 GAM42448.1 - 7.2e-05 22.4 0.0 0.054 13.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 GAM42448.1 - 0.01 15.7 0.0 0.046 13.6 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 GAM42448.1 - 0.018 14.6 0.0 2.1 7.9 0.0 2.9 3 0 0 3 3 3 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 GAM42448.1 - 0.097 12.5 0.0 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase peroxidase PF00141.23 GAM42449.1 - 5.1e-43 147.4 0.0 7.4e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF2161 PF09929.9 GAM42450.1 - 0.13 12.4 1.0 0.25 11.5 1.0 1.4 1 0 0 1 1 1 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) DUF4407 PF14362.6 GAM42450.1 - 0.33 10.2 1.2 0.43 9.9 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Amidohydro_1 PF01979.20 GAM42451.1 - 1.1e-36 126.9 0.3 1.4e-36 126.5 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM42451.1 - 7.4e-07 29.0 0.3 0.0026 17.3 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase family Alpha-amylase PF00128.24 GAM42452.1 - 2.7e-102 342.8 0.0 3.8e-102 342.3 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 GAM42452.1 - 2.8e-07 30.6 0.0 6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Alpha-amylase_C PF02806.18 GAM42452.1 - 0.0065 16.9 0.1 0.027 14.9 0.0 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain hDGE_amylase PF14701.6 GAM42452.1 - 0.02 14.0 0.0 0.075 12.1 0.0 1.8 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_32C PF08244.12 GAM42453.1 - 5e-26 91.6 0.0 8.3e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 GAM42453.1 - 6.8e-21 75.1 0.0 1.1e-20 74.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain BNR PF02012.20 GAM42453.1 - 0.0015 18.2 1.5 0.094 12.8 0.1 3.3 3 0 0 3 3 3 1 BNR/Asp-box repeat Fungal_trans PF04082.18 GAM42454.1 - 0.0057 15.7 0.2 0.018 14.0 0.0 1.9 3 0 0 3 3 3 1 Fungal specific transcription factor domain MFS_1 PF07690.16 GAM42455.1 - 6e-19 68.2 55.0 2.5e-13 49.7 37.2 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Pox_A14 PF05767.12 GAM42455.1 - 6.1 7.1 9.1 0.55 10.4 1.9 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 ADH_zinc_N_2 PF13602.6 GAM42456.1 - 6.8e-25 88.6 0.0 1.1e-24 87.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAM42456.1 - 3.2e-13 49.8 0.0 1.4e-12 47.7 0.0 1.9 1 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM42456.1 - 1.7e-07 31.1 0.1 7.9e-07 28.9 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_3 PF07859.13 GAM42457.1 - 5.6e-16 59.0 0.0 2e-07 31.1 0.0 3.6 2 1 1 3 3 3 3 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAM42457.1 - 0.15 10.9 0.2 4 6.2 0.0 2.2 1 1 1 2 2 2 0 Steryl acetyl hydrolase ParA PF10609.9 GAM42458.1 - 5.9e-85 284.6 0.1 7.1e-83 277.8 0.1 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAM42458.1 - 3.5e-13 49.7 0.0 4e-10 39.8 0.0 2.2 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAM42458.1 - 5.9e-09 36.1 1.1 3.8e-08 33.5 1.1 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 GAM42458.1 - 1.6e-06 27.6 0.1 2.5e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 GAM42458.1 - 0.0002 20.7 0.1 0.0018 17.5 0.2 2.2 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.6 GAM42458.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Ribosomal_S27e PF01667.17 GAM42458.1 - 0.0027 17.4 0.2 0.005 16.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 Fer4_NifH PF00142.18 GAM42458.1 - 0.0057 16.1 0.0 0.071 12.5 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 GAM42458.1 - 0.058 12.7 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein CBP_BcsQ PF06564.12 GAM42458.1 - 0.076 12.5 0.1 0.22 11.0 0.1 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 GAM42458.1 - 0.1 11.6 0.2 0.16 10.9 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 GAM42458.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF1610 PF07754.11 GAM42458.1 - 0.36 10.8 2.7 0.76 9.8 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) TRAUB PF08164.12 GAM42459.1 - 2.8e-32 111.1 0.1 1.4e-31 108.8 0.1 2.3 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 GAM42459.1 - 9.3e-25 87.9 3.9 9.3e-25 87.9 3.9 3.2 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor DUF2433 PF10360.9 GAM42460.1 - 4.1e-49 165.8 0.0 8e-49 164.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.7 GAM42460.1 - 0.0017 18.5 0.0 0.0056 16.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 GAM42460.1 - 0.0045 17.5 0.0 0.011 16.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PAP1 PF08601.10 GAM42461.1 - 5.4e-116 388.4 39.9 2e-106 356.9 11.1 4.0 3 1 1 4 4 4 2 Transcription factor PAP1 bZIP_1 PF00170.21 GAM42461.1 - 4e-09 36.4 10.7 1.1e-08 35.1 10.7 1.7 1 0 0 1 1 1 1 bZIP transcription factor DUF16 PF01519.16 GAM42461.1 - 0.0025 18.3 1.1 0.0069 16.9 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF16 EMP24_GP25L PF01105.24 GAM42461.1 - 0.014 15.3 0.3 0.029 14.3 0.3 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD bZIP_2 PF07716.15 GAM42461.1 - 0.026 14.6 13.7 0.061 13.4 12.6 2.1 1 1 1 2 2 2 0 Basic region leucine zipper SlyX PF04102.12 GAM42461.1 - 0.092 13.4 0.4 0.27 11.9 0.4 1.8 1 0 0 1 1 1 0 SlyX PSI_PsaF PF02507.15 GAM42461.1 - 0.15 11.9 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III SHE3 PF17078.5 GAM42461.1 - 6.9 6.3 11.9 0.055 13.2 3.7 1.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 GAM42461.1 - 7 7.2 17.8 0.16 12.5 10.1 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Tudor_3 PF18115.1 GAM42463.1 - 1.6e-08 34.3 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain SMN PF06003.12 GAM42463.1 - 1.2e-05 24.7 0.6 1.2e-05 24.7 0.6 1.5 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) DUF4537 PF15057.6 GAM42463.1 - 0.0001 22.3 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 GAM42463.1 - 0.0047 16.7 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Tudor_2 PF18104.1 GAM42463.1 - 0.0073 16.0 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain TUDOR PF00567.24 GAM42463.1 - 0.025 14.6 0.0 0.067 13.2 0.0 1.7 1 1 1 2 2 2 0 Tudor domain YbjQ_1 PF01906.17 GAM42465.1 - 8e-29 100.3 0.8 9.8e-29 100.1 0.8 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding HD PF01966.22 GAM42466.1 - 0.00013 22.2 0.1 0.00024 21.3 0.1 1.5 1 0 0 1 1 1 1 HD domain Beta-lactamase PF00144.24 GAM42469.1 - 1.2e-39 136.5 0.0 1.8e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_31 PF01055.26 GAM42470.1 - 1.5e-113 380.3 2.0 2e-113 379.9 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GAM42470.1 - 7.7e-18 64.6 0.1 8.5e-17 61.2 0.1 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like Sugar_tr PF00083.24 GAM42471.1 - 9e-98 328.1 20.2 1e-97 327.9 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM42471.1 - 7.8e-33 113.9 45.2 3.5e-28 98.6 24.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM42471.1 - 0.00065 18.3 1.5 0.00065 18.3 1.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_PK PF05891.12 GAM42471.1 - 0.17 11.4 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Fungal_trans PF04082.18 GAM42472.1 - 1.8e-13 50.1 0.0 3.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain 3Beta_HSD PF01073.19 GAM42473.1 - 2.9e-22 79.0 0.0 4.1e-17 62.1 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM42473.1 - 3.4e-20 72.5 0.1 4.7e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM42473.1 - 3.6e-19 69.3 0.1 3.6e-17 62.8 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAM42473.1 - 2.8e-08 33.3 0.1 1.3e-07 31.1 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GAM42473.1 - 5.8e-08 32.2 0.1 8.5e-06 25.1 0.1 2.1 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 GAM42473.1 - 6e-08 32.1 0.1 8.2e-08 31.7 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 GAM42473.1 - 0.00011 22.1 0.1 0.001 19.0 0.1 2.5 1 1 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 GAM42473.1 - 0.00037 20.9 0.0 0.00087 19.7 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAM42473.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Uma2 PF05685.12 GAM42473.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative restriction endonuclease p450 PF00067.22 GAM42474.1 - 1.6e-22 79.9 0.0 1.9e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 GAM42475.1 - 5.6e-17 61.8 0.0 2.6e-16 59.7 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAM42475.1 - 8.2e-07 29.1 0.1 1.3e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 GAM42475.1 - 4.5e-05 23.1 0.0 7.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NPC1_N PF16414.5 GAM42476.1 - 1.2e-84 283.7 5.6 1.8e-84 283.1 5.6 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 GAM42476.1 - 1.9e-78 264.5 9.0 9e-78 262.2 9.0 1.9 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 GAM42476.1 - 1.5e-52 177.5 7.2 1.5e-52 177.5 7.2 2.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation adh_short PF00106.25 GAM42476.1 - 1.2e-35 122.7 0.4 2.3e-35 121.8 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42476.1 - 4.1e-34 118.1 0.1 7.5e-34 117.3 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM42476.1 - 3.2e-11 43.5 0.4 6.4e-11 42.5 0.4 1.5 1 0 0 1 1 1 1 KR domain MMPL PF03176.15 GAM42476.1 - 8.7e-06 24.9 9.9 8.7e-06 24.9 9.9 3.3 4 0 0 4 4 4 1 MMPL family DUF2165 PF09933.9 GAM42476.1 - 0.035 14.1 6.3 2.5 8.1 0.9 3.2 3 0 0 3 3 3 0 Predicted small integral membrane protein (DUF2165) Alpha-amylase PF00128.24 GAM42477.1 - 6.1e-56 190.4 1.9 6.1e-56 190.4 1.9 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 GAM42477.1 - 9.2e-36 121.7 0.6 2.5e-35 120.2 0.6 1.8 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.11 GAM42477.1 - 3.4e-32 110.6 0.5 3.4e-32 110.6 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) AMPK1_CBM PF16561.5 GAM42477.1 - 0.002 18.3 0.4 0.0077 16.4 0.0 2.2 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase HEAT_EZ PF13513.6 GAM42478.1 - 3.2e-19 69.0 8.0 2.2e-05 24.8 0.0 10.5 8 2 2 10 10 10 3 HEAT-like repeat HEAT_2 PF13646.6 GAM42478.1 - 8.5e-19 67.7 3.4 0.00023 21.5 0.0 7.6 7 1 0 7 7 7 4 HEAT repeats HEAT PF02985.22 GAM42478.1 - 5.8e-17 60.3 6.0 0.00072 19.6 0.0 10.0 12 0 0 12 12 10 2 HEAT repeat Cnd1 PF12717.7 GAM42478.1 - 1.1e-11 45.1 0.4 0.00038 20.5 0.0 4.4 5 0 0 5 5 4 3 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 GAM42478.1 - 1.9e-07 30.9 0.0 8.4e-07 28.8 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain ParcG PF10274.9 GAM42478.1 - 1.8e-06 28.2 1.0 0.026 14.7 0.1 4.3 3 2 2 5 5 5 1 Parkin co-regulated protein Vac14_Fab1_bd PF12755.7 GAM42478.1 - 8.3e-06 26.3 0.0 1.5 9.5 0.0 5.7 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 GAM42478.1 - 8.4e-06 24.6 0.0 0.25 9.9 0.0 3.4 3 1 0 3 3 3 2 Adaptin N terminal region Tti2 PF10521.9 GAM42478.1 - 1.5e-05 24.7 0.1 0.27 10.7 0.0 4.4 3 1 1 4 4 4 2 Tti2 family MMS19_C PF12460.8 GAM42478.1 - 0.00019 20.7 0.2 4.3 6.4 0.0 3.7 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 GAM42478.1 - 0.00023 21.3 2.1 12 6.2 0.0 5.8 5 1 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 GAM42478.1 - 0.00084 19.0 0.0 0.3 10.6 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal DUF577 PF04510.12 GAM42478.1 - 0.0017 18.2 0.0 0.006 16.5 0.0 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF577) UNC45-central PF11701.8 GAM42478.1 - 0.013 15.4 0.4 0.36 10.8 0.3 3.2 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Arm PF00514.23 GAM42478.1 - 0.015 15.3 0.0 32 4.8 0.0 5.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 GAM42478.1 - 0.036 13.8 0.0 6.4 6.5 0.0 3.5 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis 2OG-FeII_Oxy PF03171.20 GAM42479.1 - 5.3e-16 58.9 0.0 9.4e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PEP-utilisers_N PF05524.13 GAM42481.1 - 1.2 9.3 3.7 8.3 6.6 0.4 3.0 3 1 1 4 4 4 0 PEP-utilising enzyme, N-terminal CENP-F_leu_zip PF10473.9 GAM42481.1 - 4.7 7.2 8.3 1.8 8.6 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADH_zinc_N PF00107.26 GAM42482.1 - 1.4e-25 89.7 0.6 2.6e-25 88.9 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM42482.1 - 2.5e-16 60.9 0.1 6.2e-16 59.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM42482.1 - 3.1e-11 43.1 0.0 1.6e-10 40.8 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 GAM42482.1 - 0.0011 19.2 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 GAM42482.1 - 0.0026 17.1 0.1 0.0043 16.4 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_2 PF16884.5 GAM42482.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase 2-Hacid_dh_C PF02826.19 GAM42482.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_4 PF01565.23 GAM42483.1 - 7.7e-24 84.0 0.7 1.3e-23 83.3 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain Herpes_UL49_5 PF05702.11 GAM42483.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Metallophos PF00149.28 GAM42484.1 - 3.3e-27 96.3 2.3 6e-27 95.5 2.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 GAM42484.1 - 4.5e-15 56.3 0.3 1.5e-14 54.6 0.3 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 GAM42484.1 - 1.2e-13 51.4 0.1 3.4e-13 50.0 0.1 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 GAM42484.1 - 0.039 14.5 0.2 0.11 13.1 0.1 1.8 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain fn3 PF00041.21 GAM42484.1 - 0.068 13.5 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Fibronectin type III domain Ank_2 PF12796.7 GAM42485.1 - 7.5e-45 151.4 10.7 2.4e-11 44.0 0.0 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM42485.1 - 7.7e-39 131.6 15.8 1.1e-07 32.2 0.1 6.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM42485.1 - 6.7e-30 99.8 6.4 0.0014 18.9 0.0 7.2 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 GAM42485.1 - 1.5e-26 91.6 14.9 0.00046 20.5 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 GAM42485.1 - 8.3e-25 86.5 10.5 3.6e-06 27.1 0.1 6.3 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Glyco_hydro_25 PF01183.20 GAM42486.1 - 7.5e-42 143.5 0.3 8.6e-42 143.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 OPT PF03169.15 GAM42487.1 - 9.5e-165 549.7 57.6 1.1e-164 549.5 57.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DAO PF01266.24 GAM42488.1 - 2.3e-27 96.5 0.2 2.9e-27 96.2 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM42488.1 - 0.00023 20.5 0.0 0.0003 20.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM42488.1 - 0.00048 20.3 0.5 0.0012 19.0 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 GAM42488.1 - 0.00072 19.2 1.2 0.0014 18.2 1.2 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 GAM42488.1 - 0.00099 18.3 0.7 0.0013 17.9 0.7 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAM42488.1 - 0.0078 15.3 0.6 0.012 14.8 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAM42488.1 - 0.03 13.7 0.2 0.049 13.0 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM42488.1 - 0.038 14.5 0.3 0.073 13.6 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 GAM42488.1 - 0.059 13.2 0.1 0.085 12.7 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 GAM42488.1 - 0.068 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 GAM42488.1 - 0.15 12.6 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding TauD PF02668.16 GAM42489.1 - 2.7e-29 102.8 0.1 5.9e-29 101.7 0.1 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 GAM42490.1 - 1.5e-10 40.5 32.3 1.5e-10 40.5 32.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAM42490.1 - 3.2e-10 40.0 7.6 3.2e-10 40.0 7.6 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Fungal_trans PF04082.18 GAM42491.1 - 2.5e-21 75.9 0.0 6.9e-21 74.5 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM42491.1 - 3e-09 36.8 7.2 5.4e-09 36.0 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KfrA_N PF11740.8 GAM42491.1 - 0.031 15.0 2.5 0.099 13.3 1.5 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term 2-Hacid_dh_C PF02826.19 GAM42492.1 - 9.3e-45 152.2 0.0 1.7e-44 151.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAM42492.1 - 0.00016 21.3 0.0 0.00038 20.1 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAM42492.1 - 0.00051 20.2 0.0 0.00087 19.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase THDPS_N_2 PF14805.6 GAM42492.1 - 0.0029 17.8 0.5 0.0071 16.5 0.1 1.8 2 0 0 2 2 2 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal DUF2567 PF10821.8 GAM42494.1 - 0.021 14.9 1.1 0.021 14.9 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2567) adh_short PF00106.25 GAM42495.1 - 2.6e-33 115.1 0.0 3.5e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42495.1 - 3.3e-26 92.3 0.0 4.2e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.19 GAM42495.1 - 0.027 13.8 0.0 0.22 10.9 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.8 GAM42495.1 - 0.032 14.0 1.2 0.12 12.2 0.2 2.3 2 1 1 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 GAM42495.1 - 0.033 13.6 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 GAM42495.1 - 0.043 13.8 0.1 0.22 11.5 0.0 2.1 2 1 0 2 2 2 0 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 GAM42495.1 - 0.14 11.4 0.2 0.31 10.3 0.2 1.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.10 GAM42495.1 - 0.15 12.0 0.1 2.2 8.2 0.1 2.2 1 1 0 1 1 1 0 KR domain Amidohydro_1 PF01979.20 GAM42496.1 - 1.9e-58 198.4 0.0 2.3e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM42496.1 - 4.1e-12 46.3 0.0 4.9e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 GAM42496.1 - 0.00068 19.1 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase adh_short PF00106.25 GAM42497.1 - 1.4e-21 76.8 0.0 2e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42497.1 - 1.1e-15 57.8 0.1 1.5e-15 57.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM42497.1 - 1.6e-06 28.2 0.0 2.4e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM42497.1 - 2e-06 27.5 0.0 0.054 12.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM42497.1 - 0.00033 20.6 0.1 0.00049 20.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAM42497.1 - 0.00042 19.8 0.3 0.025 14.0 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAM42497.1 - 0.0023 17.6 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 GAM42497.1 - 0.0071 15.5 0.2 0.16 11.0 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein DUF421 PF04239.12 GAM42497.1 - 0.052 13.3 0.2 4.6 7.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF421) adh_short PF00106.25 GAM42498.1 - 5.7e-18 65.1 0.2 1.4e-17 63.8 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM42498.1 - 8.2e-10 38.9 0.0 1.6e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 GAM42498.1 - 1.5e-08 34.5 0.0 2.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PEX11 PF05648.14 GAM42499.1 - 2.9e-34 118.5 0.0 3.3e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) F-actin_cap_A PF01267.17 GAM42500.1 - 2.7e-95 318.8 0.0 3.1e-95 318.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF3188 PF11384.8 GAM42502.1 - 0.0027 17.4 0.7 0.0068 16.1 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3188) PIRT PF15099.6 GAM42502.1 - 0.04 13.5 0.2 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DAG1 PF05454.11 GAM42502.1 - 0.058 12.8 1.1 0.82 9.0 0.0 2.5 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EphA2_TM PF14575.6 GAM42502.1 - 0.1 13.5 0.0 0.41 11.6 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 GAM42502.1 - 0.2 11.5 0.0 0.2 11.5 0.0 3.3 3 0 0 3 3 3 0 TMEM154 protein family SNF2_N PF00176.23 GAM42503.1 - 6.7e-63 212.5 0.1 1.4e-62 211.4 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM42503.1 - 1.4e-17 64.0 0.0 1.2e-16 61.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 GAM42503.1 - 4e-09 36.2 2.9 8.7e-09 35.1 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM42503.1 - 3.3e-08 33.2 2.0 3.3e-08 33.2 2.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 GAM42503.1 - 1.1e-06 28.8 0.0 4.5e-06 26.8 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 GAM42503.1 - 1.2e-05 25.5 3.6 3e-05 24.3 3.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAM42503.1 - 2.5e-05 24.1 3.3 5.2e-05 23.0 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM42503.1 - 0.00012 22.1 1.7 0.00025 21.0 1.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAM42503.1 - 0.00029 20.7 3.7 0.00029 20.7 3.7 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 GAM42503.1 - 0.00064 19.5 4.0 0.0018 18.0 4.0 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 GAM42503.1 - 0.003 17.4 4.6 0.016 15.0 4.6 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 SDA1 PF05285.12 GAM42503.1 - 0.01 15.3 22.0 0.024 14.1 22.0 1.5 1 0 0 1 1 1 0 SDA1 zf-C3HC4_4 PF15227.6 GAM42503.1 - 0.026 14.7 5.1 0.067 13.4 5.1 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_14 PF17978.1 GAM42503.1 - 0.068 13.6 0.5 0.15 12.5 0.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 GAM42503.1 - 0.091 12.5 0.4 0.22 11.3 0.4 1.6 1 0 0 1 1 1 0 RING-like zinc finger Nop14 PF04147.12 GAM42503.1 - 0.36 9.0 19.2 0.75 7.9 19.2 1.5 1 0 0 1 1 1 0 Nop14-like family DZR PF12773.7 GAM42503.1 - 0.57 10.3 5.0 1.8 8.7 5.1 1.7 1 1 0 1 1 1 0 Double zinc ribbon CDC45 PF02724.14 GAM42503.1 - 0.61 8.3 21.0 1.2 7.3 21.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 GAM42503.1 - 1.3 7.1 4.1 2.2 6.3 4.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ras PF00071.22 GAM42504.1 - 1.3e-40 138.6 0.0 2.1e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Nas2_N PF18265.1 GAM42504.1 - 2.2e-29 101.2 0.1 4e-29 100.4 0.1 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain Roc PF08477.13 GAM42504.1 - 7.4e-21 74.6 0.0 2.2e-20 73.1 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase PDZ_6 PF17820.1 GAM42504.1 - 4.4e-13 48.9 0.4 7.8e-13 48.1 0.4 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAM42504.1 - 1.6e-07 31.5 0.5 7.6e-07 29.4 0.1 2.3 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 GAM42504.1 - 1.9e-06 28.1 0.1 3.7e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Arf PF00025.21 GAM42504.1 - 5.4e-05 22.7 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family RhoGEF PF00621.20 GAM42505.1 - 3.6e-18 66.4 1.8 5.7e-18 65.8 1.8 1.3 1 0 0 1 1 1 1 RhoGEF domain SBDS PF01172.18 GAM42506.1 - 1.4e-25 89.2 0.1 1.7e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein UDG PF03167.19 GAM42507.1 - 4e-18 65.9 0.0 6.7e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF2130 PF09903.9 GAM42508.1 - 0.011 15.0 5.4 0.02 14.1 5.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Phage_GP20 PF06810.11 GAM42508.1 - 0.055 13.3 7.0 0.1 12.4 7.0 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 UPF0242 PF06785.11 GAM42508.1 - 0.12 12.4 7.5 0.18 11.9 7.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 GAM42508.1 - 0.16 11.3 1.2 0.26 10.6 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YlqD PF11068.8 GAM42508.1 - 0.26 11.7 10.6 0.075 13.4 7.6 1.6 2 0 0 2 2 2 0 YlqD protein DUF4337 PF14235.6 GAM42508.1 - 0.28 11.3 2.2 0.44 10.7 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HIP1_clath_bdg PF16515.5 GAM42508.1 - 0.4 11.3 12.8 0.13 12.9 9.2 1.9 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2884 PF11101.8 GAM42508.1 - 0.44 10.0 7.3 0.13 11.8 4.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) ACCA PF03255.14 GAM42508.1 - 0.52 10.2 5.5 0.9 9.4 5.5 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TMPIT PF07851.13 GAM42508.1 - 0.61 9.3 3.8 0.91 8.7 3.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein BST2 PF16716.5 GAM42508.1 - 0.9 10.2 12.2 0.47 11.1 9.5 1.9 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 ArAE_2_N PF10337.9 GAM42508.1 - 1.2 8.1 3.5 1.8 7.5 3.5 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal XhlA PF10779.9 GAM42508.1 - 1.6 9.0 7.0 3.6 7.9 7.0 1.7 1 0 0 1 1 1 0 Haemolysin XhlA Glyco_hydro_106 PF17132.4 GAM42509.1 - 1.2e-24 86.7 0.9 3.8e-24 85.0 0.1 2.0 2 0 0 2 2 2 1 alpha-L-rhamnosidase Glyco_hydro_2_N PF02837.18 GAM42509.1 - 0.037 13.9 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain AA_permease_2 PF13520.6 GAM42510.1 - 1.4e-52 179.0 48.3 1.8e-52 178.6 48.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM42510.1 - 1.8e-18 66.4 43.6 2.3e-18 66.1 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 GAM42510.1 - 0.34 9.7 3.1 0.66 8.7 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Tweety PF04906.13 GAM42510.1 - 1.3 7.6 5.8 0.12 11.0 0.6 1.9 2 0 0 2 2 2 0 Tweety Acetyltransf_2 PF00797.17 GAM42511.1 - 1.6e-43 149.3 0.0 2.4e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase Fumarate_red_D PF02313.17 GAM42512.1 - 5.7 7.1 8.9 7.5 6.7 0.9 2.6 2 0 0 2 2 2 0 Fumarate reductase subunit D HKR_ArcB_TM PF18415.1 GAM42512.1 - 7.9 7.4 9.6 1.5 9.7 0.5 2.9 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain EthD PF07110.11 GAM42513.1 - 0.12 13.6 0.0 0.27 12.4 0.0 1.7 1 0 0 1 1 1 0 EthD domain FAD_binding_8 PF08022.12 GAM42514.1 - 1.7e-21 76.4 0.0 3.6e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 GAM42514.1 - 2.6e-21 76.4 0.0 4.3e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 GAM42514.1 - 7e-19 68.2 7.1 7e-19 68.2 7.1 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 GAM42514.1 - 0.15 12.4 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NRDE-2 PF08424.10 GAM42515.1 - 4.1e-98 328.4 3.9 1.8e-96 323.1 3.7 2.7 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference Spem1 PF15670.5 GAM42515.1 - 0.37 10.3 5.9 0.93 9.0 5.9 1.6 1 0 0 1 1 1 0 Spermatid maturation protein 1 Peptidase_S49_N PF08496.10 GAM42515.1 - 0.55 10.3 2.4 0.62 10.1 0.3 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal BP28CT PF08146.12 GAM42516.1 - 2.5e-42 144.4 2.0 1.3e-41 142.1 1.5 2.6 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 GAM42516.1 - 1.9e-24 86.3 1.6 1.9e-24 86.3 1.6 5.9 5 1 1 6 6 6 1 U3 small nucleolar RNA-associated protein 10 Tti2 PF10521.9 GAM42516.1 - 0.00068 19.3 0.8 0.11 12.0 0.0 3.8 4 0 0 4 4 4 1 Tti2 family HEAT_EZ PF13513.6 GAM42516.1 - 0.0027 18.2 11.0 1.1 9.9 0.1 7.0 9 0 0 9 9 9 1 HEAT-like repeat Cnd1 PF12717.7 GAM42516.1 - 0.0099 15.9 3.7 1.9 8.5 0.0 4.9 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAM42516.1 - 0.031 14.5 8.9 1.2 9.6 0.0 5.9 6 0 0 6 6 6 0 HEAT repeat Nipped-B_C PF12830.7 GAM42516.1 - 0.071 13.1 4.0 0.54 10.2 0.1 4.0 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus Cas_APE2256 PF09651.10 GAM42516.1 - 0.17 11.8 0.4 0.53 10.2 0.1 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) Ank_2 PF12796.7 GAM42517.1 - 1.4e-42 144.2 0.0 3.9e-10 40.2 0.0 5.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM42517.1 - 2.6e-31 107.2 1.9 4.5e-07 30.0 0.0 7.3 4 2 4 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM42517.1 - 2.7e-30 104.3 5.2 1.4e-05 25.6 0.0 7.4 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM42517.1 - 3.3e-26 88.5 0.1 0.013 16.0 0.0 9.9 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 GAM42517.1 - 1.7e-23 82.0 0.1 0.019 15.4 0.0 10.2 10 0 0 10 10 10 5 Ankyrin repeat NACHT PF05729.12 GAM42517.1 - 4.8e-09 36.3 0.0 1.1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GAM42517.1 - 0.00076 19.8 0.0 0.0023 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAM42517.1 - 0.082 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Bul1_N PF04425.12 GAM42518.1 - 5e-05 22.2 0.5 0.00026 19.9 0.2 2.1 2 0 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.12 GAM42518.1 - 6.4e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus Arrestin_N PF00339.29 GAM42518.1 - 0.00067 19.7 0.0 0.0026 17.8 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Sulfatase PF00884.23 GAM42519.1 - 1.5e-60 205.2 0.1 1.9e-60 204.8 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 GAM42519.1 - 1.6e-20 72.7 0.7 2.8e-20 71.9 0.7 1.4 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 GAM42519.1 - 5.9e-12 45.8 0.2 1.4e-05 24.8 0.0 2.5 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 GAM42519.1 - 0.0041 16.2 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF229 PF02995.17 GAM42519.1 - 0.0079 14.8 0.0 0.01 14.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.6 GAM42519.1 - 0.0095 16.7 0.3 0.026 15.3 0.2 1.8 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 GAM42519.1 - 0.09 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Metalloenzyme PF01676.18 GAM42519.1 - 0.092 12.1 0.0 0.56 9.5 0.0 2.0 2 0 0 2 2 2 0 Metalloenzyme superfamily EMP70 PF02990.16 GAM42520.1 - 5.7e-197 655.5 0.1 6.8e-197 655.2 0.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 ubiquitin PF00240.23 GAM42521.1 - 1.1e-21 76.4 0.0 1.6e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAM42521.1 - 3.2e-09 36.5 0.0 5.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 GAM42521.1 - 3.9e-08 33.0 0.1 1e-07 31.7 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 GAM42521.1 - 2.2e-06 27.8 0.0 4.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAM42521.1 - 4.2e-06 27.3 0.0 9.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain YukD PF08817.10 GAM42521.1 - 0.004 17.8 0.0 0.016 15.9 0.0 2.0 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.6 GAM42521.1 - 0.0087 16.5 0.1 0.023 15.1 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Blt1 PF12754.7 GAM42521.1 - 0.021 15.2 0.1 0.045 14.1 0.1 1.6 1 0 0 1 1 1 0 Blt1 N-terminal domain STI1 PF17830.1 GAM42521.1 - 0.055 13.4 17.2 1.7 8.7 1.7 3.7 2 1 1 3 3 3 0 STI1 domain GerD PF17898.1 GAM42521.1 - 6.8 6.7 5.7 4.6 7.2 2.9 2.1 2 1 1 3 3 3 0 Spore germination GerD central core domain MMS1_N PF10433.9 GAM42522.1 - 2.1e-136 455.4 0.1 1.1e-89 301.3 0.0 2.7 2 1 1 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GAM42522.1 - 1.3e-100 336.9 0.0 1.1e-99 333.8 0.0 2.3 3 0 0 3 3 3 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 GAM42522.1 - 0.0089 16.3 0.0 0.33 11.3 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 GAM42522.1 - 0.074 13.0 0.1 27 4.8 0.0 3.5 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal CN_hydrolase PF00795.22 GAM42523.1 - 3.3e-30 105.3 0.1 5.8e-29 101.2 0.1 2.1 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase GrpB PF04229.14 GAM42524.1 - 1.2e-46 158.8 0.0 1.4e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Asparaginase_2 PF01112.18 GAM42525.1 - 1.5e-46 158.8 1.0 7.1e-39 133.6 0.2 2.2 2 0 0 2 2 2 2 Asparaginase tRNA-synt_2 PF00152.20 GAM42525.1 - 1.5e-22 80.1 0.0 2.2e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) HIT PF01230.23 GAM42525.1 - 1.6e-08 35.2 0.0 0.012 16.4 0.0 2.6 2 0 0 2 2 2 2 HIT domain tRNA-synt_2d PF01409.20 GAM42525.1 - 0.00011 21.8 0.1 0.14 11.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) ArAE_2_N PF10337.9 GAM42527.1 - 5.7e-32 111.4 12.2 1.2e-28 100.4 10.0 3.6 2 1 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 GAM42527.1 - 1.8e-11 44.3 18.1 1.8e-11 44.3 18.1 2.5 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 GAM42527.1 - 0.00036 20.4 0.1 0.0019 18.1 0.1 2.3 1 1 0 1 1 1 1 Aromatic acid exporter family member 2 BING4CT PF08149.11 GAM42527.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 BING4CT (NUC141) domain DUF4407 PF14362.6 GAM42527.1 - 0.63 9.3 0.0 0.63 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF445 PF04286.12 GAM42528.1 - 0.12 12.1 3.2 0.65 9.8 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF445) RGS12_us2 PF16611.5 GAM42528.1 - 0.26 11.7 4.5 0.82 10.1 4.5 1.9 1 0 0 1 1 1 0 Unstructured region between RBD and GoLoco Pyridoxal_deC PF00282.19 GAM42529.1 - 4.6e-78 262.6 0.0 6.3e-78 262.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GAM42529.1 - 0.00024 20.2 0.0 0.0004 19.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 GAM42529.1 - 0.0099 14.6 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain TPR_1 PF00515.28 GAM42530.1 - 5e-08 32.4 3.4 0.031 14.1 0.5 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM42530.1 - 1e-07 31.5 2.3 0.052 13.7 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM42530.1 - 0.0046 17.1 1.7 1.3 9.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM42530.1 - 0.013 16.1 0.1 0.67 10.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM42530.1 - 0.02 15.4 0.7 0.13 12.8 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM42530.1 - 0.19 11.8 2.9 23 5.2 0.4 3.2 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat PhetRS_B1 PF18262.1 GAM42531.1 - 0.0096 16.1 0.1 6.8 7.0 0.0 2.3 2 0 0 2 2 2 2 Phe-tRNA synthetase beta subunit B1 domain SSXT PF05030.12 GAM42532.1 - 0.00061 19.4 0.0 0.014 15.0 0.0 3.1 3 0 0 3 3 3 2 SSXT protein (N-terminal region) BRF1 PF07741.13 GAM42532.1 - 1.2 9.6 6.0 2.6 8.4 6.0 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Pox_A11 PF05061.13 GAM42532.1 - 1.3 8.2 4.5 1.8 7.8 4.5 1.1 1 0 0 1 1 1 0 Poxvirus A11 Protein Presenilin PF01080.17 GAM42532.1 - 2.8 6.6 12.5 4 6.1 12.5 1.4 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 GAM42532.1 - 3.9 7.3 12.6 5.8 6.7 12.6 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TCP PF03634.13 GAM42532.1 - 5.9 7.4 12.3 0.81 10.2 8.2 1.7 2 0 0 2 2 2 0 TCP family transcription factor PDZ_1 PF12812.7 GAM42533.1 - 7.3e-54 179.7 0.0 1.8e-35 120.8 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 GAM42533.1 - 2e-24 87.2 0.9 3.7e-21 76.6 0.1 2.7 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 GAM42533.1 - 2.8e-19 68.7 0.9 2e-09 37.1 0.4 4.7 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 GAM42533.1 - 5.3e-14 52.3 0.1 9.6e-06 25.8 0.0 4.0 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 GAM42533.1 - 4.9e-12 46.0 0.0 4.1e-05 23.8 0.0 3.7 3 0 0 3 3 3 3 PDZ domain Trypsin PF00089.26 GAM42533.1 - 0.00073 19.4 0.0 0.0031 17.4 0.0 2.0 1 1 0 1 1 1 1 Trypsin 4HPAD_g_N PF18671.1 GAM42533.1 - 0.005 16.5 0.0 0.015 15.0 0.0 1.9 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Tricorn_PDZ PF14685.6 GAM42533.1 - 0.0069 16.3 0.3 0.9 9.6 0.1 3.7 4 0 0 4 4 4 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 GAM42533.1 - 0.023 13.4 0.1 0.048 12.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S7 PF00949.21 GAM42533.1 - 0.11 12.4 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease MFS_1 PF07690.16 GAM42534.1 - 2.5e-05 23.4 16.5 9.9e-05 21.4 10.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily HMG_box PF00505.19 GAM42534.1 - 0.0095 16.3 0.0 1.3 9.5 0.1 2.7 2 0 0 2 2 2 1 HMG (high mobility group) box ESSS PF10183.9 GAM42534.1 - 0.13 12.4 2.6 0.73 10.1 0.1 2.9 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) V_ATPase_I PF01496.19 GAM42534.1 - 0.14 10.0 0.0 0.2 9.6 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GFA PF04828.14 GAM42535.1 - 3.3e-05 24.2 1.2 3.3e-05 24.2 1.2 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Thymidylat_synt PF00303.19 GAM42536.1 - 3.1e-108 361.0 0.0 3.5e-108 360.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Peptidase_A4 PF01828.17 GAM42537.1 - 1.2e-76 256.9 13.1 1.4e-76 256.6 13.1 1.1 1 0 0 1 1 1 1 Peptidase A4 family NmrA PF05368.13 GAM42538.1 - 1.1e-20 74.2 0.0 1.4e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 GAM42538.1 - 0.00013 22.2 0.2 0.0028 17.9 0.1 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAM42538.1 - 0.0094 16.0 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 GAM42538.1 - 0.076 13.5 0.0 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding CHAT PF12770.7 GAM42539.1 - 0.035 13.5 0.0 0.095 12.1 0.0 1.8 1 1 0 1 1 1 0 CHAT domain GST_N PF02798.20 GAM42540.1 - 8.4e-17 61.3 0.0 1.2e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAM42540.1 - 8.6e-14 51.7 0.0 1.3e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM42540.1 - 2.7e-09 37.2 0.0 3.9e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM42540.1 - 0.00013 22.1 0.0 0.00021 21.4 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 GAM42540.1 - 0.0077 16.6 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM42540.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GAM42540.1 - 0.12 13.1 0.0 0.18 12.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 GAM42540.1 - 0.18 12.1 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Zn_clus PF00172.18 GAM42541.1 - 0.0019 18.3 2.4 0.0036 17.4 2.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 GAM42542.1 - 2e-34 119.1 0.3 2.4e-34 118.8 0.3 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM42542.1 - 4.8e-05 22.9 0.1 0.00029 20.4 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAM42542.1 - 0.00023 20.8 0.1 0.00041 20.0 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 GAM42542.1 - 0.0074 15.3 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PAC2 PF09754.9 GAM42542.1 - 0.057 13.4 0.0 0.063 13.3 0.0 1.1 1 0 0 1 1 1 0 PAC2 family HTH_53 PF18606.1 GAM42542.1 - 0.14 11.9 0.0 0.57 9.9 0.0 2.0 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain TPR_12 PF13424.6 GAM42543.1 - 1.5e-27 95.7 9.5 2.7e-09 37.2 0.0 5.2 4 1 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAM42543.1 - 1.2e-20 72.6 16.7 1.6e-05 24.6 0.0 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAM42543.1 - 3e-10 39.4 4.5 1 9.6 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM42543.1 - 2.2e-07 30.6 7.4 0.0017 17.8 0.0 3.6 2 2 1 3 3 3 2 MalT-like TPR region TPR_19 PF14559.6 GAM42543.1 - 2.9e-07 30.9 3.5 2.2 8.8 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM42543.1 - 5.2e-06 27.0 5.9 0.13 13.0 0.1 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat PPR PF01535.20 GAM42543.1 - 5.3e-05 23.2 0.1 0.3 11.4 0.0 4.4 5 1 0 5 5 3 1 PPR repeat TPR_14 PF13428.6 GAM42543.1 - 0.00026 21.5 11.9 11 7.1 0.0 6.5 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAM42543.1 - 0.00044 20.6 2.2 5.1 8.0 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM42543.1 - 0.0096 16.1 0.2 15 6.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM42543.1 - 0.015 15.3 2.1 20 5.6 0.0 5.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM42543.1 - 0.019 14.6 0.9 1.5 8.6 0.0 3.8 4 1 0 4 4 4 0 TPR repeat TPR_6 PF13174.6 GAM42543.1 - 0.2 12.4 2.8 1.8e+02 3.1 0.0 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat INCENP_ARK-bind PF03941.15 GAM42544.1 - 2.8e-16 59.2 2.9 2.8e-16 59.2 2.9 2.6 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Reticulon PF02453.17 GAM42545.1 - 6.1e-27 94.5 4.2 8.7e-27 94.0 4.2 1.2 1 0 0 1 1 1 1 Reticulon YL1 PF05764.13 GAM42546.1 - 4.3e-05 23.8 9.9 7e-05 23.1 9.9 1.2 1 0 0 1 1 1 1 YL1 nuclear protein DNA_topoisoIV PF00521.20 GAM42547.1 - 4.1e-138 460.9 1.4 1.3e-137 459.2 0.3 2.1 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 GAM42547.1 - 6.3e-54 181.7 7.0 2.2e-53 179.9 7.0 2.1 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 GAM42547.1 - 7.3e-26 90.7 2.6 7.3e-26 90.7 2.6 2.0 2 0 0 2 2 2 1 DNA gyrase B HATPase_c PF02518.26 GAM42547.1 - 5.2e-16 59.1 0.1 1.9e-15 57.3 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 GAM42547.1 - 7.3e-07 29.4 0.0 5e-06 26.7 0.0 2.5 2 0 0 2 2 2 1 Toprim domain Glyoxal_oxid_N PF07250.11 GAM42547.1 - 0.17 11.0 0.0 0.41 9.8 0.0 1.5 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus RabGAP-TBC PF00566.18 GAM42548.1 - 1.3e-28 100.1 2.8 7.4e-23 81.3 1.9 3.1 2 1 1 3 3 3 2 Rab-GTPase-TBC domain MSC PF09402.10 GAM42548.1 - 2 7.8 15.1 3.7 6.9 2.1 2.5 1 1 1 2 2 2 0 Man1-Src1p-C-terminal domain Fungal_trans PF04082.18 GAM42550.1 - 0.014 14.4 0.2 0.038 13.0 0.2 1.7 1 1 0 1 1 1 0 Fungal specific transcription factor domain Pyr_redox_2 PF07992.14 GAM42551.1 - 5e-35 121.2 0.1 6.8e-35 120.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM42551.1 - 8.8e-13 48.6 0.4 7.1e-11 42.5 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM42551.1 - 7.7e-07 28.7 0.1 2.4e-06 27.0 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM42551.1 - 0.0014 17.8 0.0 0.0035 16.6 0.0 1.6 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) SBDS_C PF09377.10 GAM42552.1 - 1.7e-44 150.6 0.0 3.1e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 GAM42552.1 - 1e-31 108.8 0.3 2.1e-31 107.9 0.3 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein AP3D1 PF06375.11 GAM42552.1 - 0.0081 16.4 1.0 0.019 15.2 1.0 1.6 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 Peptidase_S10 PF00450.22 GAM42553.1 - 1.3e-131 439.9 0.3 1.5e-131 439.6 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 GAM42553.1 - 5.8e-14 52.7 0.1 1.5e-13 51.3 0.1 1.8 2 0 0 2 2 2 1 Carboxypeptidase Y pro-peptide ApoLp-III PF07464.11 GAM42553.1 - 0.0023 18.0 0.0 0.0043 17.2 0.0 1.3 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Ribosomal_S13 PF00416.22 GAM42554.1 - 3.4e-56 189.1 3.3 3.9e-56 188.9 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 GAM42554.1 - 0.06 12.1 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.8 GAM42554.1 - 0.098 13.1 0.0 0.21 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2746) HHH_6 PF14579.6 GAM42554.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix motif Med4 PF10018.9 GAM42555.1 - 3.8e-42 144.2 3.0 5.2e-42 143.7 3.0 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 RP-C_C PF11800.8 GAM42555.1 - 0.0023 18.1 1.7 0.0027 17.8 0.8 1.6 1 1 0 1 1 1 1 Replication protein C C-terminal region Pes-10 PF07149.11 GAM42555.1 - 0.032 13.3 1.4 0.044 12.8 1.4 1.2 1 0 0 1 1 1 0 Pes-10 DNA_pol_phi PF04931.13 GAM42555.1 - 0.04 12.1 7.6 0.048 11.8 7.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 GAM42555.1 - 0.05 14.0 7.2 0.13 12.6 7.2 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2151 PF10221.9 GAM42555.1 - 0.89 8.1 5.0 4.3 5.8 0.5 2.0 1 1 1 2 2 2 0 Cell cycle and development regulator CDC45 PF02724.14 GAM42555.1 - 1.7 6.8 7.5 2.1 6.5 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GAM42555.1 - 1.8 8.7 17.5 3 7.9 17.5 1.4 1 1 0 1 1 1 0 YL1 nuclear protein RRN3 PF05327.11 GAM42555.1 - 5.1 5.5 6.2 6.5 5.2 6.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 GAM42555.1 - 7.3 5.8 13.5 0.78 9.0 9.3 1.5 2 0 0 2 2 2 0 NOA36 protein MFS_1 PF07690.16 GAM42556.1 - 4.4e-24 85.1 19.7 4.4e-24 85.1 19.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ExbD PF02472.16 GAM42556.1 - 0.14 12.4 0.1 0.24 11.6 0.1 1.3 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR MFS_1 PF07690.16 GAM42557.1 - 6.7e-27 94.3 28.0 6.7e-27 94.3 28.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF202 PF02656.15 GAM42558.1 - 2.4e-16 59.9 0.6 9.1e-16 58.1 0.1 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF202) Rhodanese PF00581.20 GAM42559.1 - 5.7e-17 62.2 0.0 4.3e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain 3Beta_HSD PF01073.19 GAM42560.1 - 3.2e-13 49.3 0.1 4.5e-11 42.3 0.1 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM42560.1 - 1.3e-10 41.1 0.3 6.8e-10 38.8 0.1 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAM42560.1 - 1.4e-07 30.9 0.2 6.3e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 GAM42560.1 - 6.1e-07 29.1 0.4 1.4e-06 28.0 0.4 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAM42560.1 - 6.5e-06 26.2 0.1 1.1e-05 25.4 0.1 1.4 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 GAM42560.1 - 4.2e-05 23.2 0.1 0.00012 21.7 0.2 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 GAM42560.1 - 0.004 16.6 0.1 0.29 10.6 0.2 2.9 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 GAM42560.1 - 0.0077 15.4 0.2 0.13 11.4 0.2 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain Fungal_trans PF04082.18 GAM42561.1 - 2.5e-12 46.4 0.0 4.7e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-CCCH_4 PF18044.1 GAM42561.1 - 0.00033 20.4 2.3 0.00033 20.4 2.3 4.3 4 0 0 4 4 4 1 CCCH-type zinc finger zf-CCCH PF00642.24 GAM42561.1 - 0.0015 18.3 1.6 0.0015 18.3 1.6 3.5 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RSS_P20 PF11757.8 GAM42561.1 - 0.19 12.2 0.4 0.86 10.1 0.4 2.1 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain zf_CCCH_4 PF18345.1 GAM42561.1 - 3 8.0 15.1 0.098 12.7 3.7 3.6 3 0 0 3 3 3 0 Zinc finger domain MFS_1 PF07690.16 GAM42562.1 - 5.4e-20 71.6 53.6 3.3e-13 49.3 30.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PepSY_TM PF03929.16 GAM42562.1 - 1.2 8.8 6.4 0.56 9.8 1.7 2.4 2 0 0 2 2 2 0 PepSY-associated TM region GMC_oxred_N PF00732.19 GAM42564.1 - 1.1e-63 215.4 0.0 1.4e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM42564.1 - 9.4e-34 117.0 0.0 1.8e-33 116.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAM42564.1 - 1.1e-05 24.7 0.9 2.1e-05 23.7 0.3 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAM42564.1 - 0.00031 20.9 1.2 0.00059 20.0 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM42564.1 - 0.00059 19.5 3.6 0.0028 17.3 3.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM42564.1 - 0.0018 17.4 1.1 0.055 12.6 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 GAM42564.1 - 0.049 13.9 0.5 0.23 11.7 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.14 GAM42564.1 - 0.083 12.1 0.5 0.27 10.4 0.1 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM42564.1 - 0.18 11.0 1.0 4.1 6.6 0.8 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM42564.1 - 0.18 11.0 0.8 0.77 8.9 0.2 2.0 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 GAM42564.1 - 0.19 10.5 0.2 0.26 10.1 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase COesterase PF00135.28 GAM42565.1 - 4.1e-45 154.6 0.0 6e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM42565.1 - 0.0063 16.4 0.5 0.023 14.6 0.5 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Sugar_tr PF00083.24 GAM42566.1 - 6.9e-67 226.3 30.9 8e-67 226.0 30.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM42566.1 - 1.1e-13 50.9 32.3 1.1e-13 50.9 32.3 2.5 1 1 2 3 3 3 1 Major Facilitator Superfamily DUF5085 PF16895.5 GAM42566.1 - 0.18 12.1 0.1 0.51 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5085) DUF3425 PF11905.8 GAM42567.1 - 2.5e-25 88.9 0.7 4e-25 88.2 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Reprolysin_5 PF13688.6 GAM42568.1 - 1.3e-48 165.7 2.0 2.5e-48 164.9 2.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAM42568.1 - 7e-42 143.4 0.2 1.2e-41 142.6 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 GAM42568.1 - 6.2e-32 111.1 1.1 1e-31 110.4 1.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 GAM42568.1 - 2e-08 34.8 0.1 1.2e-07 32.3 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 GAM42568.1 - 7e-06 26.1 1.3 2.6e-05 24.2 1.3 1.8 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 GAM42568.1 - 0.00021 21.6 0.0 0.0004 20.6 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide adh_short PF00106.25 GAM42569.1 - 1.6e-29 102.7 0.0 3.2e-29 101.8 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42569.1 - 1.5e-18 67.3 0.0 2e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAM42569.1 - 0.0088 15.5 0.1 0.053 13.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAM42569.1 - 0.017 15.1 1.4 0.23 11.4 0.3 2.4 2 1 0 2 2 2 0 KR domain DLH PF01738.18 GAM42570.1 - 5.9e-06 26.0 0.1 5.5e-05 22.8 0.1 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 GAM42570.1 - 0.00042 20.3 0.0 0.00094 19.2 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 GAM42570.1 - 0.0026 16.5 0.3 0.063 12.0 0.1 2.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 GAM42570.1 - 0.023 14.0 0.2 0.079 12.2 0.2 1.9 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 GAM42570.1 - 0.044 12.7 0.0 0.91 8.4 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase enzyme Peptidase_S9 PF00326.21 GAM42570.1 - 0.088 12.3 1.0 0.57 9.6 0.6 2.4 2 1 1 3 3 3 0 Prolyl oligopeptidase family ADH_zinc_N PF00107.26 GAM42571.1 - 2.3e-17 63.2 0.1 3.3e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM42571.1 - 3.9e-05 23.5 0.0 6.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 GAM42571.1 - 0.027 13.9 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Urocanase PF01175.18 GAM42571.1 - 0.11 12.1 0.1 9.5 5.8 0.0 2.1 2 0 0 2 2 2 0 Urocanase Rossmann-like domain COesterase PF00135.28 GAM42572.1 - 1.7e-32 113.0 0.1 2.1e-32 112.7 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM42572.1 - 0.00013 21.9 0.0 0.00015 21.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 GAM42572.1 - 0.0084 15.6 3.3 0.014 14.9 2.9 1.4 1 1 0 1 1 1 1 Esterase PHB depolymerase Zn_clus PF00172.18 GAM42574.1 - 3.2e-09 36.8 13.9 5.4e-09 36.0 13.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAM42574.1 - 5.3e-09 35.4 0.8 1.4e-08 33.9 0.2 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain DUF4122 PF13498.6 GAM42574.1 - 0.15 11.7 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) zf-RVT PF13966.6 GAM42575.1 - 0.00029 21.5 0.0 0.00057 20.5 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase FAD_binding_4 PF01565.23 GAM42576.1 - 1e-22 80.4 3.1 2.4e-22 79.2 3.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM42576.1 - 3.9e-12 46.1 3.4 6.4e-12 45.4 1.2 2.3 2 0 0 2 2 2 1 Berberine and berberine like DUF3937 PF13073.6 GAM42577.1 - 2.1 8.5 5.9 0.28 11.3 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3937) Glyco_hydro_92 PF07971.12 GAM42578.1 - 1.2e-144 482.7 0.4 1.5e-144 482.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 GAM42578.1 - 1.1e-64 218.6 3.6 3.1e-64 217.1 3.6 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain LIP PF03583.14 GAM42581.1 - 0.0018 17.7 4.6 0.29 10.4 2.6 2.2 2 0 0 2 2 2 2 Secretory lipase Peptidase_S9 PF00326.21 GAM42581.1 - 0.016 14.7 0.3 0.04 13.4 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family E1_dh PF00676.20 GAM42582.1 - 1.9e-100 335.7 0.0 2.3e-100 335.4 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 GAM42582.1 - 0.00068 19.5 1.6 0.0013 18.5 1.6 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 GAM42582.1 - 0.00089 18.5 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Rad4 PF03835.15 GAM42583.1 - 1.8e-37 128.3 0.1 5.1e-37 126.8 0.1 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 GAM42583.1 - 2.9e-27 94.8 0.1 1.1e-26 93.1 0.1 2.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 GAM42583.1 - 9.1e-23 79.9 0.2 2e-22 78.8 0.2 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 GAM42583.1 - 1.4e-13 51.6 0.1 1.4e-13 51.6 0.1 2.8 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 GAM42583.1 - 0.022 15.2 0.0 0.092 13.2 0.0 2.1 1 1 0 1 1 1 0 Transglutaminase-like superfamily DUF5435 PF17503.2 GAM42584.1 - 0.018 14.7 0.2 0.067 12.9 0.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5435) Aminotran_3 PF00202.21 GAM42585.1 - 3e-92 309.4 0.0 4.4e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans_2 PF11951.8 GAM42585.1 - 9e-10 37.9 0.0 7.5e-06 25.0 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Aminotran_1_2 PF00155.21 GAM42585.1 - 0.0011 18.2 0.1 0.0034 16.6 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II BSD PF03909.17 GAM42586.1 - 3.6e-20 71.7 1.4 7.4e-20 70.7 1.4 1.6 1 0 0 1 1 1 1 BSD domain DUF572 PF04502.13 GAM42586.1 - 0.028 14.1 15.6 0.088 12.4 2.3 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF572) MDMPI_N PF11716.8 GAM42586.1 - 0.066 13.9 1.5 0.13 13.0 0.2 2.2 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain TBCC_N PF16752.5 GAM42586.1 - 1.4 9.4 7.4 7.2 7.1 3.0 3.0 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Suf PF05843.14 GAM42586.1 - 2.1 8.2 8.9 0.51 10.3 5.2 1.7 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) Ran-binding PF05508.11 GAM42587.1 - 2.4e-121 404.5 0.9 3.4e-121 404.0 0.9 1.2 1 0 0 1 1 1 1 RanGTP-binding protein DHDPS PF00701.22 GAM42587.1 - 0.11 11.1 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family GTP_EFTU PF00009.27 GAM42588.1 - 1.3e-40 139.1 0.0 2.1e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAM42588.1 - 5.2e-28 97.6 0.0 1.1e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAM42588.1 - 2.1e-06 28.0 0.2 5.6e-06 26.7 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAM42588.1 - 0.028 14.5 0.0 0.18 11.9 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase CDC27 PF09507.10 GAM42588.1 - 9.6 5.5 17.7 14 5.0 17.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 WGG PF10273.9 GAM42590.1 - 8.6e-29 100.0 0.2 1.5e-28 99.2 0.2 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Vfa1 PF08432.10 GAM42590.1 - 0.12 12.7 2.1 0.17 12.2 2.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RXT2_N PF08595.11 GAM42590.1 - 0.16 12.0 4.4 0.23 11.5 4.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 GAM42590.1 - 0.25 9.6 5.9 0.23 9.7 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3245 PF11595.8 GAM42590.1 - 0.8 10.2 7.8 1.5 9.3 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) DNA_pol_phi PF04931.13 GAM42590.1 - 1.1 7.3 12.9 1.6 6.7 12.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 GAM42590.1 - 2 7.7 13.6 2.8 7.2 13.6 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 GAM42590.1 - 3.7 8.0 13.9 7.9 6.9 13.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pes-10 PF07149.11 GAM42590.1 - 8.3 5.3 8.5 12 4.9 8.5 1.2 1 0 0 1 1 1 0 Pes-10 CIAPIN1 PF05093.13 GAM42591.1 - 1.1e-39 135.0 5.3 1.8e-39 134.3 5.3 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 GAM42591.1 - 5.4e-37 127.0 0.0 8.1e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus SKG6 PF08693.10 GAM42592.1 - 2.9e-06 26.6 0.1 6.5e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CFEM PF05730.11 GAM42592.1 - 0.00063 19.8 7.2 0.0011 19.0 7.2 1.3 1 0 0 1 1 1 1 CFEM domain VSP PF03302.13 GAM42592.1 - 0.0014 17.6 0.1 0.0025 16.8 0.1 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 GAM42592.1 - 0.0037 17.4 0.3 0.0037 17.4 0.3 1.7 2 0 0 2 2 2 1 Podoplanin MLANA PF14991.6 GAM42592.1 - 0.066 13.5 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein melan-A TMEM154 PF15102.6 GAM42592.1 - 0.25 11.3 1.4 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family RNase_H PF00075.24 GAM42593.1 - 1.1e-10 41.8 0.0 2.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 RNase H Amidase PF01425.21 GAM42594.1 - 2.1e-68 231.3 0.1 2.9e-65 221.0 0.0 2.1 2 0 0 2 2 2 2 Amidase Isochorismatase PF00857.20 GAM42597.1 - 8.6e-31 107.5 0.0 9.6e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family AP_endonuc_2 PF01261.24 GAM42598.1 - 3e-43 147.7 0.0 3.9e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel 6PGD PF00393.19 GAM42599.1 - 3.2e-88 295.9 0.0 3.9e-88 295.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 GAM42599.1 - 7e-35 120.5 0.0 1.1e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 GAM42599.1 - 8.1e-07 29.1 0.1 1.4e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 GAM42599.1 - 0.0014 18.7 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 GAM42599.1 - 0.0018 17.7 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 GAM42599.1 - 0.0059 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 GAM42599.1 - 0.02 15.4 0.1 0.047 14.3 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 GAM42599.1 - 0.047 13.3 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 GAM42599.1 - 0.075 13.6 0.2 0.21 12.2 0.2 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 GAM42599.1 - 0.094 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RSF PF14876.6 GAM42599.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator NAD_binding_8 PF13450.6 GAM42599.1 - 0.14 12.4 0.1 0.4 10.9 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Metallophos PF00149.28 GAM42600.1 - 1.9e-15 57.9 0.0 2.8e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RHH_4 PF13467.6 GAM42600.1 - 0.096 12.6 0.1 21 5.1 0.0 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix domain DUF4690 PF15756.5 GAM42601.1 - 0.0023 18.5 2.5 0.0056 17.2 2.5 1.6 1 0 0 1 1 1 1 Small Novel Rich in Cartilage DUF4448 PF14610.6 GAM42601.1 - 0.005 16.6 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF347 PF03988.12 GAM42601.1 - 0.092 12.9 4.6 0.23 11.7 4.6 1.7 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Glyco_hydro_28 PF00295.17 GAM42602.1 - 9e-105 350.3 20.8 9e-105 350.3 20.8 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 PNP_UDP_1 PF01048.20 GAM42603.1 - 2.2e-38 131.8 0.3 3.9e-38 131.0 0.3 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Fungal_trans PF04082.18 GAM42603.1 - 2.4e-12 46.5 0.2 1.2e-11 44.2 0.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF572 PF04502.13 GAM42604.1 - 2.4e-68 231.2 4.4 3e-68 230.9 4.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) MFS_1 PF07690.16 GAM42604.1 - 1.4e-42 145.9 27.6 2.5e-42 145.1 25.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42604.1 - 1.5e-10 40.6 8.4 1.5e-10 40.6 8.4 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 GAM42604.1 - 4.8e-06 25.3 5.3 8.3e-06 24.5 5.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 GAM42604.1 - 0.0029 16.1 0.3 0.0055 15.2 0.3 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector Atg14 PF10186.9 GAM42604.1 - 4.4 6.3 9.3 7.9 5.5 9.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PTPA PF03095.15 GAM42605.1 - 9.5e-119 396.3 0.0 1.1e-118 396.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF2115 PF09888.9 GAM42606.1 - 0.1 13.1 0.6 0.32 11.5 0.6 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF1515 PF07439.11 GAM42606.1 - 1.6 8.8 4.0 2.7 8.0 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF3140 PF11338.8 GAM42606.1 - 2.8 8.4 7.4 1.1 9.8 2.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) ATG16 PF08614.11 GAM42607.1 - 0.00075 19.8 32.4 0.00075 19.8 32.4 9.8 1 1 7 9 9 9 4 Autophagy protein 16 (ATG16) Spc7 PF08317.11 GAM42607.1 - 0.0014 17.6 12.1 0.0014 17.6 12.1 9.6 1 1 9 10 10 10 4 Spc7 kinetochore protein SOAR PF16533.5 GAM42607.1 - 0.0079 16.1 4.1 0.0079 16.1 4.1 10.5 2 2 4 10 10 10 1 STIM1 Orai1-activating region BUD22 PF09073.10 GAM42608.1 - 8.5e-110 368.0 37.5 9.7e-110 367.9 37.5 1.0 1 0 0 1 1 1 1 BUD22 PRTP PF01366.18 GAM42608.1 - 6.6 4.6 6.5 0.55 8.2 1.9 1.5 2 0 0 2 2 2 0 Herpesvirus processing and transport protein Complex1_30kDa PF00329.19 GAM42609.1 - 2.2e-45 154.2 0.0 3e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.6 GAM42610.1 - 2.5e-19 68.8 13.3 4.1e-19 68.1 13.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 GAM42610.1 - 4.1e-06 26.6 7.7 6.8e-06 25.8 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 GAM42610.1 - 0.00068 19.4 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 GAM42610.1 - 0.0012 19.1 11.5 0.0021 18.3 11.5 1.4 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 GAM42610.1 - 0.0016 18.4 5.2 0.0027 17.7 5.2 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 GAM42610.1 - 0.22 11.4 9.6 1.6 8.7 9.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 GAM42610.1 - 0.24 11.3 12.7 0.44 10.5 12.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MCLC PF05934.11 GAM42610.1 - 1.4 7.5 5.9 2.7 6.6 5.9 1.4 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DZR PF12773.7 GAM42610.1 - 2.8 8.0 10.2 37 4.4 10.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_UBOX PF13445.6 GAM42610.1 - 5.2 7.2 10.8 11 6.2 10.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger E1_dh PF00676.20 GAM42611.1 - 2.1e-68 230.5 0.1 1.5e-63 214.5 0.0 2.1 1 1 1 2 2 2 2 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 GAM42611.1 - 0.00058 19.7 0.4 0.012 15.4 0.4 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SidC_N PF18219.1 GAM42611.1 - 0.049 12.6 0.1 0.068 12.1 0.1 1.1 1 0 0 1 1 1 0 SidC N-terminal domain DXP_synthase_N PF13292.6 GAM42611.1 - 0.19 10.9 0.0 0.4 9.8 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Malate_DH PF12434.8 GAM42611.1 - 0.36 10.9 5.2 2.2 8.4 0.3 2.8 2 0 0 2 2 2 0 Malate dehydrogenase enzyme GST_N_3 PF13417.6 GAM42612.1 - 1.4e-12 47.8 0.0 2.1e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM42612.1 - 1.2e-05 25.5 0.0 1.7e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAM42612.1 - 2.2e-05 24.7 0.0 3.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Amidase02_C PF12123.8 GAM42612.1 - 0.068 12.9 0.1 0.48 10.2 0.0 2.4 4 0 0 4 4 4 0 N-acetylmuramoyl-l-alanine amidase Acetyltransf_10 PF13673.7 GAM42613.1 - 2.4e-10 40.4 0.0 4.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM42613.1 - 3.7e-10 40.1 0.0 7e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM42613.1 - 4.2e-10 39.9 0.0 8.9e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 GAM42613.1 - 0.00044 20.3 0.0 0.00093 19.3 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 GAM42613.1 - 0.0039 17.3 0.0 0.011 15.8 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAM42613.1 - 0.0084 16.8 0.0 0.28 11.8 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM42613.1 - 0.046 13.7 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Amidase PF01425.21 GAM42614.1 - 1.5e-22 80.2 0.2 2.2e-22 79.7 0.2 1.1 1 0 0 1 1 1 1 Amidase Hint PF01079.20 GAM42614.1 - 0.039 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Hint module Lipase_3 PF01764.25 GAM42614.1 - 0.18 11.6 0.5 0.73 9.7 0.7 2.1 2 1 0 2 2 2 0 Lipase (class 3) Ig_mannosidase PF17753.1 GAM42617.1 - 3.5e-19 68.3 0.2 2.5e-18 65.6 0.1 2.5 2 0 0 2 2 2 1 Ig-fold domain Mannosidase_ig PF17786.1 GAM42617.1 - 2.1e-13 50.7 1.4 1e-12 48.5 0.1 2.8 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 GAM42617.1 - 1.2e-09 38.9 0.1 1.4e-08 35.3 0.1 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 DUF4217 PF13959.6 GAM42617.1 - 0.096 12.9 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) PEP_mutase PF13714.6 GAM42618.1 - 1.7e-40 139.0 0.1 2e-40 138.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 GAM42618.1 - 8.6e-22 77.3 0.0 1.2e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF1275 PF06912.11 GAM42619.1 - 1.3e-45 155.8 13.4 1.5e-45 155.5 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3953 PF13129.6 GAM42619.1 - 0.021 14.6 3.9 3 7.7 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3953) Gly-zipper_Omp PF13488.6 GAM42619.1 - 0.046 13.7 3.4 0.28 11.2 0.7 2.4 2 0 0 2 2 2 0 Glycine zipper DUF4149 PF13664.6 GAM42619.1 - 0.35 11.2 4.9 0.65 10.3 2.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) HRG PF16954.5 GAM42619.1 - 1.9 9.0 7.3 0.21 12.0 1.7 2.4 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Transgly_assoc PF04226.13 GAM42619.1 - 5.7 7.3 10.2 0.58 10.5 1.3 3.1 3 1 1 4 4 4 0 Transglycosylase associated protein Aldedh PF00171.22 GAM42620.1 - 1.3e-86 290.9 1.4 3.9e-68 230.0 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF423 PF04241.15 GAM42621.1 - 0.96 9.7 4.0 1.6 9.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF423) CYYR1 PF10873.8 GAM42621.1 - 3.1 8.2 6.5 19 5.7 0.1 2.7 3 0 0 3 3 3 0 Cysteine and tyrosine-rich protein 1 MFS_1 PF07690.16 GAM42622.1 - 1.9e-50 171.7 27.5 1.9e-50 171.7 27.5 2.7 3 0 0 3 3 3 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 GAM42622.1 - 4e-39 134.7 0.0 3.1e-37 128.5 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 GAM42622.1 - 4.2e-25 88.6 0.0 3.6e-24 85.5 0.1 2.0 1 1 1 2 2 2 1 Dienelactone hydrolase family Sugar_tr PF00083.24 GAM42622.1 - 1.2e-14 54.0 2.0 1.2e-14 54.0 2.0 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.18 GAM42622.1 - 1.1e-08 34.5 0.2 1.8e-08 33.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRI12 PF06609.13 GAM42622.1 - 6.8e-05 21.5 0.8 0.00011 20.8 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) COesterase PF00135.28 GAM42622.1 - 0.049 12.5 0.0 0.11 11.4 0.0 1.4 1 1 0 1 1 1 0 Carboxylesterase family Abhydrolase_1 PF00561.20 GAM42622.1 - 0.13 11.9 0.0 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold adh_short PF00106.25 GAM42623.1 - 1.3e-25 90.0 0.0 8.6e-21 74.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42623.1 - 2.9e-11 43.4 0.0 3.6e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAM42623.1 - 1.5e-05 24.6 0.0 2.2e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAM42623.1 - 5.5e-05 23.2 0.0 9.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 GAM42623.1 - 0.00046 19.7 0.1 0.0008 18.9 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAM42623.1 - 0.0075 15.4 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 GAM42623.1 - 0.014 15.4 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.12 GAM42623.1 - 0.041 13.0 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Bac_luciferase PF00296.20 GAM42624.1 - 1.2e-58 199.0 0.2 1.6e-58 198.6 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Glyco_hydro_3_C PF01915.22 GAM42625.1 - 7.1e-45 153.5 0.0 1.2e-44 152.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAM42625.1 - 9.2e-43 146.8 0.0 1.4e-42 146.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM42625.1 - 8.2e-20 70.7 0.2 1.4e-19 69.9 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Fungal_trans PF04082.18 GAM42626.1 - 2.8e-12 46.3 0.3 1.1e-11 44.3 0.3 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM42626.1 - 0.00028 20.9 14.3 0.00047 20.2 14.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAM42626.1 - 0.013 14.3 1.0 0.31 9.8 0.0 2.7 3 0 0 3 3 3 0 Fungal specific transcription factor domain DUF3445 PF11927.8 GAM42628.1 - 1.8e-70 237.1 0.0 2.2e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_hydro_79C PF16862.5 GAM42629.1 - 2e-14 54.3 0.2 4.7e-14 53.1 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_2 PF00703.21 GAM42630.1 - 1.3e-15 58.0 0.9 3.1e-15 56.8 0.3 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 GAM42630.1 - 6.4e-08 33.1 0.2 9.3e-07 29.4 0.0 2.8 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 GAM42630.1 - 0.00035 20.3 0.1 0.0011 18.7 0.1 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 GAM42630.1 - 0.039 13.8 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Ig_GlcNase PF18368.1 GAM42630.1 - 0.081 13.1 0.4 2 8.6 0.0 2.9 3 0 0 3 3 3 0 Exo-beta-D-glucosaminidase Ig-fold domain GFO_IDH_MocA PF01408.22 GAM42631.1 - 5.6e-20 72.4 0.0 1.1e-19 71.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 GAM42631.1 - 0.0053 17.3 0.2 0.019 15.5 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 GAM42631.1 - 0.0055 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAM42631.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PhyH PF05721.13 GAM42632.1 - 2.1e-14 54.3 0.0 2.9e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 GAM42632.1 - 0.054 13.9 0.0 0.18 12.3 0.0 1.8 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Zn_clus PF00172.18 GAM42633.1 - 5.2e-06 26.5 3.2 9.4e-06 25.7 3.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 GAM42634.1 - 1.1e-62 212.4 29.7 5.4e-47 160.7 11.1 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM42634.1 - 3.5e-07 29.5 23.6 3.5e-07 29.5 23.6 3.5 1 1 2 3 3 3 3 Major Facilitator Superfamily Phage_holin_1 PF04531.13 GAM42634.1 - 3.4 8.3 9.2 2.4 8.7 2.1 2.8 1 1 1 2 2 2 0 Bacteriophage holin UPF0139 PF03669.13 GAM42634.1 - 5.5 6.9 5.7 6.1 6.8 3.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) HSP70 PF00012.20 GAM42635.1 - 2.3e-09 36.0 0.2 1.8e-08 33.0 0.2 1.9 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAM42635.1 - 0.024 13.5 0.4 0.14 10.9 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein N2227 PF07942.12 GAM42636.1 - 9.9e-92 307.0 0.0 1.2e-91 306.7 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 GAM42636.1 - 0.009 15.9 0.0 0.018 14.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM42636.1 - 0.016 15.8 0.0 0.05 14.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAM42636.1 - 0.025 15.3 0.0 0.18 12.6 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain DUF16 PF01519.16 GAM42637.1 - 6.8 7.2 14.9 3.4 8.2 11.3 2.3 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF2278 PF10042.9 GAM42638.1 - 4.9e-70 235.7 0.8 7.6e-70 235.1 0.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) MFS_1 PF07690.16 GAM42639.1 - 6e-37 127.4 33.8 6e-37 127.4 33.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42639.1 - 1.4e-13 50.5 5.2 1.4e-13 50.5 5.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 GAM42639.1 - 7.1e-07 28.8 4.4 8.5e-07 28.6 0.3 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB FA_desaturase PF00487.24 GAM42639.1 - 0.045 13.6 16.1 0.027 14.3 5.6 2.6 2 1 0 2 2 2 0 Fatty acid desaturase ArAE_2_N PF10337.9 GAM42639.1 - 0.059 12.4 0.6 0.11 11.5 0.6 1.4 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Orthopox_A5L PF06193.11 GAM42640.1 - 0.68 9.3 11.8 1 8.8 11.8 1.2 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Mucin PF01456.17 GAM42640.1 - 1.1 9.3 26.7 0.13 12.3 22.4 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Glyco_hydro_3 PF00933.21 GAM42641.1 - 1.7e-13 50.6 0.0 2.1e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAM42641.1 - 0.0088 16.1 0.2 0.014 15.5 0.1 1.4 2 0 0 2 2 2 1 Fibronectin type III-like domain PhetRS_B1 PF18262.1 GAM42641.1 - 0.075 13.3 0.0 0.17 12.1 0.0 1.6 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain HEM4 PF02602.15 GAM42641.1 - 0.076 12.4 0.0 0.088 12.1 0.0 1.1 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD AA_permease PF00324.21 GAM42642.1 - 3.3e-123 411.8 49.9 4.1e-123 411.5 49.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM42642.1 - 2.7e-32 112.2 53.3 3.7e-32 111.7 53.3 1.1 1 0 0 1 1 1 1 Amino acid permease Alpha-amylase PF00128.24 GAM42643.1 - 2.6e-20 73.3 0.0 5.3e-20 72.2 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 GAM42643.1 - 2.8e-06 25.9 0.4 0.064 11.4 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Mito_carr PF00153.27 GAM42645.1 - 3.5e-45 151.9 7.1 5.9e-17 61.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Amidase PF01425.21 GAM42646.1 - 2.1e-91 307.2 0.1 5.8e-80 269.5 0.1 2.0 1 1 0 2 2 2 2 Amidase p450 PF00067.22 GAM42647.1 - 6.2e-47 160.4 0.0 1.2e-46 159.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 PorA PF11271.8 GAM42648.1 - 0.00088 18.7 1.4 0.00088 18.7 1.4 1.7 2 1 0 2 2 2 1 Porin PorA adh_short_C2 PF13561.6 GAM42649.1 - 2.1e-43 148.6 0.6 2.8e-43 148.2 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM42649.1 - 8.6e-41 139.5 0.2 1.4e-40 138.8 0.1 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAM42649.1 - 4.1e-12 46.4 0.2 7e-12 45.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Paxillin PF03535.13 GAM42649.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Paxillin family Acetyltransf_7 PF13508.7 GAM42650.1 - 6.9e-10 39.2 0.0 1.8e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM42650.1 - 8.4e-09 35.7 0.2 2.3e-08 34.3 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM42650.1 - 1.4e-08 34.8 0.0 3.2e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM42650.1 - 0.0012 18.9 0.0 0.0045 17.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM42650.1 - 0.036 14.0 0.1 0.11 12.4 0.1 1.8 1 1 0 1 1 1 0 FR47-like protein PAP_central PF04928.17 GAM42651.1 - 4e-110 366.7 0.0 5.1e-110 366.3 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 GAM42651.1 - 1.7e-59 200.3 0.0 2.5e-59 199.7 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 GAM42651.1 - 3.4e-11 43.3 0.0 7.2e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 GAM42651.1 - 0.17 11.6 0.1 0.41 10.4 0.1 1.6 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain DUF3817 PF12823.7 GAM42652.1 - 0.15 12.9 0.0 0.16 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3817) Fungal_trans PF04082.18 GAM42653.1 - 1.5e-17 63.5 0.1 3e-15 56.0 0.0 2.7 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM42653.1 - 4.4e-06 26.7 13.8 7e-06 26.1 13.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Viral_P18 PF04521.13 GAM42653.1 - 0.088 12.6 2.9 0.094 12.5 1.0 2.0 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Say1_Mug180 PF10340.9 GAM42654.1 - 4.5e-27 94.9 0.0 6.3e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 GAM42654.1 - 2.3e-22 79.9 0.0 3.3e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAM42654.1 - 0.006 15.5 0.2 0.076 11.9 0.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.16 GAM42654.1 - 0.0079 16.0 0.1 0.89 9.3 0.0 2.8 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Tri3 PF07428.11 GAM42655.1 - 1.8e-188 626.6 0.0 2.1e-188 626.4 0.0 1.0 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 AATase PF07247.12 GAM42655.1 - 0.00021 20.0 0.1 0.051 12.1 0.0 2.1 2 0 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.20 GAM42655.1 - 0.085 11.5 0.0 2.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Condensation domain Flavin_Reduct PF01613.18 GAM42656.1 - 9.4e-19 68.0 0.0 2e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Flavin reductase like domain Mucin PF01456.17 GAM42657.1 - 1.7 8.7 6.4 2.2 8.3 6.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Pyr_redox_2 PF07992.14 GAM42658.1 - 5.9e-35 120.9 0.0 2.2e-31 109.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM42658.1 - 4.8e-09 36.7 0.0 1.9e-07 31.6 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM42658.1 - 0.14 10.8 0.0 0.59 8.8 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein CMD PF02627.20 GAM42659.1 - 3.2e-05 23.9 0.0 0.00045 20.2 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Leukocidin PF07968.12 GAM42659.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Leukocidin/Hemolysin toxin family NmrA PF05368.13 GAM42660.1 - 0.035 13.7 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.16 GAM42661.1 - 0.0006 18.8 0.4 0.00072 18.6 0.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ATP19 PF11022.8 GAM42662.1 - 0.081 13.3 0.1 32 5.0 0.0 2.9 1 1 1 2 2 2 0 ATP synthase subunit K PAZ PF02170.22 GAM42662.1 - 0.11 12.2 10.2 5.6 6.8 0.2 3.0 1 1 2 3 3 3 0 PAZ domain DUF4484 PF14831.6 GAM42662.1 - 0.23 11.5 2.5 3.1 7.8 2.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) Imm31 PF15591.6 GAM42662.1 - 3 7.8 5.2 58 3.6 0.1 2.9 1 1 2 3 3 3 0 Immunity protein 31 Rnf-Nqr PF02508.14 GAM42663.1 - 0.1 12.6 1.8 0.15 12.1 1.8 1.3 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein RNase_H PF00075.24 GAM42664.1 - 4.8e-09 36.5 0.0 1e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 RNase H Sfi1_C PF10638.9 GAM42664.1 - 0.015 16.1 0.1 0.028 15.1 0.1 1.4 1 0 0 1 1 1 0 Spindle body associated protein C-terminus ABC_tran PF00005.27 GAM42665.1 - 3e-46 157.4 0.1 1.7e-26 93.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAM42665.1 - 1.3e-25 90.6 12.2 1.3e-25 90.6 12.2 3.0 2 1 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.6 GAM42665.1 - 5e-12 46.2 0.0 0.00027 20.8 0.0 3.7 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM42665.1 - 1.1e-09 38.0 0.9 0.0054 16.2 0.1 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAM42665.1 - 1.5e-08 35.0 0.8 0.0096 16.2 0.4 3.4 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAM42665.1 - 2.5e-08 34.0 0.6 0.0027 17.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 GAM42665.1 - 4.5e-08 32.7 0.5 0.0033 17.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAM42665.1 - 3.5e-07 30.9 0.7 0.0039 17.7 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAM42665.1 - 1.1e-06 29.2 0.1 0.047 14.1 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 GAM42665.1 - 7.9e-05 22.8 0.3 0.0038 17.3 0.0 2.3 2 0 0 2 2 2 1 Dynamin family cobW PF02492.19 GAM42665.1 - 8.3e-05 22.2 1.0 0.18 11.4 0.4 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 GAM42665.1 - 0.00014 21.7 0.2 0.17 11.5 0.2 2.2 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 GAM42665.1 - 0.00017 20.8 0.3 0.2 10.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_7 PF12775.7 GAM42665.1 - 0.00018 21.1 0.2 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 GAM42665.1 - 0.00022 21.4 0.2 1.1 9.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 GAM42665.1 - 0.00038 20.9 0.1 0.34 11.3 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 GAM42665.1 - 0.0012 18.1 0.2 0.1 11.8 0.0 2.7 2 1 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 GAM42665.1 - 0.0012 19.4 0.0 0.66 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAM42665.1 - 0.0016 18.2 0.2 0.14 11.8 0.0 3.0 3 0 0 3 3 2 1 IstB-like ATP binding protein Roc PF08477.13 GAM42665.1 - 0.0017 18.6 0.2 0.6 10.3 0.0 3.1 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 GAM42665.1 - 0.002 17.9 0.2 0.1 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAM42665.1 - 0.0035 17.3 0.4 4.6 7.2 0.1 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 GAM42665.1 - 0.0042 16.8 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 GAM42665.1 - 0.0043 16.9 0.4 1.7 8.4 0.0 2.5 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 GAM42665.1 - 0.0059 16.7 0.1 4.2 7.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 GAM42665.1 - 0.0089 15.0 2.4 1 8.2 0.0 2.9 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.6 GAM42665.1 - 0.0091 15.6 0.0 1.5 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAM42665.1 - 0.011 16.0 1.7 4.2 7.7 0.1 3.2 4 0 0 4 4 2 0 AAA domain TsaE PF02367.17 GAM42665.1 - 0.014 15.4 0.1 6.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 GAM42665.1 - 0.043 13.7 2.0 1.3 8.9 0.0 3.0 3 0 0 3 3 2 0 NTPase ATP_bind_1 PF03029.17 GAM42665.1 - 0.045 13.5 0.1 9.2 6.0 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Rad17 PF03215.15 GAM42665.1 - 0.064 13.2 0.1 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 GAM42665.1 - 0.069 13.4 1.0 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 GAM42665.1 - 0.072 12.9 0.3 1.6 8.5 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase ABC_ATPase PF09818.9 GAM42665.1 - 0.077 11.8 1.4 1 8.1 0.2 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Adeno_IVa2 PF02456.15 GAM42665.1 - 0.084 11.7 0.9 1.3 7.8 0.2 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein NACHT PF05729.12 GAM42665.1 - 0.089 12.7 0.3 12 5.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_35 PF14516.6 GAM42665.1 - 0.09 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Pox_A32 PF04665.12 GAM42665.1 - 0.091 12.2 0.3 2.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.12 GAM42665.1 - 0.093 12.0 0.3 7.6 5.8 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin ATPase_2 PF01637.18 GAM42665.1 - 0.099 12.5 0.1 20 5.0 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 GAM42665.1 - 0.14 11.9 1.7 12 5.6 0.1 3.0 3 0 0 3 3 3 0 Cytidylate kinase RNA_helicase PF00910.22 GAM42665.1 - 0.14 12.5 0.1 17 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 GAM42665.1 - 0.15 11.2 0.3 1 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PRK PF00485.18 GAM42665.1 - 0.17 11.6 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_PrkA PF08298.11 GAM42665.1 - 0.2 10.6 0.1 1.5 7.6 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain TMEM125 PF15109.6 GAM42665.1 - 2.4 8.5 6.8 0.74 10.2 0.6 3.3 3 0 0 3 3 2 0 TMEM125 protein family Lsm_interact PF05391.11 GAM42665.1 - 6.8 6.3 5.3 2.1 8.0 0.1 2.4 2 0 0 2 2 2 0 Lsm interaction motif MFS_1 PF07690.16 GAM42666.1 - 5.6e-23 81.4 18.6 9.9e-23 80.6 18.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily HSP20 PF00011.21 GAM42667.1 - 1.9e-11 44.0 0.9 1.9e-11 44.0 0.9 2.1 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAM42667.1 - 0.0013 18.2 0.3 0.088 12.4 0.0 2.8 2 1 1 3 3 3 1 HSP20-like domain found in ArsA Ank_2 PF12796.7 GAM42668.1 - 8.6e-49 164.1 0.1 2.1e-15 57.1 0.1 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM42668.1 - 3.7e-42 142.2 6.5 2.4e-11 43.9 0.1 7.0 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 GAM42668.1 - 1.5e-39 132.7 4.6 2.8e-06 27.5 0.0 9.1 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.6 GAM42668.1 - 3.7e-35 115.9 1.4 0.00017 21.8 0.0 9.2 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 GAM42668.1 - 1e-30 105.4 2.9 8.7e-07 29.1 0.1 7.0 4 2 3 7 7 7 6 Ankyrin repeats (many copies) CorA PF01544.18 GAM42668.1 - 4.3e-14 52.5 0.5 4.3e-14 52.5 0.5 2.4 4 0 0 4 4 4 1 CorA-like Mg2+ transporter protein DUF5089 PF17002.5 GAM42668.1 - 0.0049 16.8 4.5 0.0049 16.8 4.5 2.5 3 1 1 4 4 3 1 Domain of unknown function (DUF5089) CENP-B_N PF04218.13 GAM42668.1 - 0.013 15.2 0.1 0.14 11.9 0.0 2.4 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain GLE1 PF07817.13 GAM42668.1 - 0.11 11.7 0.6 0.24 10.6 0.6 1.5 1 0 0 1 1 1 0 GLE1-like protein HBS1_N PF08938.10 GAM42668.1 - 0.26 11.6 2.6 0.78 10.1 2.6 1.9 1 0 0 1 1 1 0 HBS1 N-terminus FAM76 PF16046.5 GAM42668.1 - 2.2 7.5 16.5 0.21 10.9 4.9 2.4 2 0 0 2 2 2 0 FAM76 protein A_deaminase PF00962.22 GAM42669.1 - 5.1e-38 131.2 0.0 6e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 GAM42669.1 - 0.00083 18.8 0.1 0.0012 18.2 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM42669.1 - 0.0026 17.3 0.0 0.0045 16.5 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family MFS_1 PF07690.16 GAM42670.1 - 1.4e-31 109.7 29.9 2e-31 109.2 29.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM42670.1 - 6.9e-06 25.6 17.2 1.5e-05 24.5 3.5 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF1727 PF08353.10 GAM42670.1 - 0.12 12.3 0.4 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1727) LRR_8 PF13855.6 GAM42672.1 - 0.46 10.3 2.5 14 5.5 0.0 3.7 4 1 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 GAM42672.1 - 7.3 7.2 9.4 14 6.3 0.0 4.6 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) TRI5 PF06330.11 GAM42673.1 - 1e-26 93.7 1.5 2.3e-26 92.5 1.5 1.4 1 1 0 1 1 1 1 Trichodiene synthase (TRI5) p450 PF00067.22 GAM42674.1 - 7e-79 265.7 0.1 8.2e-79 265.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4166 PF13761.6 GAM42674.1 - 0.23 11.3 1.1 2 8.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4166) WD40 PF00400.32 GAM42675.1 - 3.5e-20 72.0 2.0 1.6e-11 44.6 0.0 3.7 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM42675.1 - 2.6e-06 27.6 0.0 0.0003 21.0 0.0 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 GAM42675.1 - 0.001 19.0 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Ret2_MD PF18528.1 GAM42675.1 - 0.0019 18.5 0.0 0.25 11.7 0.0 2.2 2 0 0 2 2 2 1 RNA editing 3' terminal uridylyl transferase 2 middle domain Proteasome_A_N PF10584.9 GAM42675.1 - 0.0074 15.9 0.0 2.5 7.9 0.0 2.7 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature Ge1_WD40 PF16529.5 GAM42675.1 - 0.039 12.9 0.0 0.15 11.0 0.0 1.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PNP_UDP_1 PF01048.20 GAM42676.1 - 5.8e-06 25.7 0.1 6.2e-06 25.6 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily MFS_1 PF07690.16 GAM42677.1 - 1.7e-32 112.8 50.9 1.7e-32 112.8 50.9 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42677.1 - 1.1e-09 37.7 12.1 1.1e-09 37.7 12.1 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter InaF-motif PF15018.6 GAM42677.1 - 6.5 6.7 8.8 0.75 9.7 1.9 3.0 2 0 0 2 2 2 0 TRP-interacting helix Aminotran_1_2 PF00155.21 GAM42678.1 - 5.5e-14 52.1 0.0 7.4e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Hemerythrin PF01814.23 GAM42679.1 - 1.7e-13 51.3 1.1 2.5e-13 50.8 1.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TCTP PF00838.17 GAM42679.1 - 0.013 15.9 0.1 0.017 15.5 0.1 1.1 1 0 0 1 1 1 0 Translationally controlled tumour protein TetR_C_37 PF18665.1 GAM42679.1 - 0.22 12.1 2.1 11 6.6 0.2 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain F-box-like PF12937.7 GAM42680.1 - 0.001 18.9 0.8 0.001 18.9 0.8 2.8 3 1 0 3 3 3 1 F-box-like F-box PF00646.33 GAM42680.1 - 0.0046 16.8 0.3 0.012 15.5 0.3 1.7 1 0 0 1 1 1 1 F-box domain Glyco_hydro_35 PF01301.19 GAM42681.1 - 3.7e-84 283.1 0.8 5e-84 282.6 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 GAM42681.1 - 3.5e-60 202.9 0.0 6e-60 202.1 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 GAM42681.1 - 4.7e-59 197.9 8.7 5.3e-34 117.2 0.5 2.8 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 GAM42681.1 - 1.3e-20 72.7 0.4 3.5e-20 71.3 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Pyr_redox_2 PF07992.14 GAM42682.1 - 8.7e-52 176.2 0.1 1.1e-51 175.8 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM42682.1 - 6e-23 81.2 0.0 2.5e-19 69.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAM42682.1 - 4.2e-22 78.5 0.1 9.1e-22 77.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 GAM42682.1 - 2e-10 40.4 0.4 7.7e-08 31.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM42682.1 - 1.2e-07 31.9 2.3 0.0034 17.6 0.1 3.3 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAM42682.1 - 1.5e-07 30.8 4.3 0.00038 19.7 1.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.6 GAM42682.1 - 2.5e-06 26.9 0.0 0.00035 19.8 0.0 2.6 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 GAM42682.1 - 5e-06 26.1 1.6 0.012 15.0 0.1 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAM42682.1 - 5.6e-05 22.5 0.2 0.06 12.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 GAM42682.1 - 0.0001 21.2 1.1 0.22 10.2 0.2 2.9 2 1 0 2 2 2 2 HI0933-like protein 3HCDH_N PF02737.18 GAM42682.1 - 0.00025 21.0 0.6 0.012 15.6 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAM42682.1 - 0.00038 19.8 0.3 0.0019 17.5 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 GAM42682.1 - 0.002 17.3 3.8 0.0022 17.1 0.1 2.4 2 1 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 GAM42682.1 - 0.0048 17.3 0.1 0.13 12.7 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding XdhC_C PF13478.6 GAM42682.1 - 0.0051 17.3 0.0 0.22 12.0 0.0 2.4 2 0 0 2 2 2 1 XdhC Rossmann domain NAD_Gly3P_dh_N PF01210.23 GAM42682.1 - 0.0099 15.9 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 GAM42682.1 - 0.012 14.9 0.1 0.047 12.9 0.0 2.0 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 GAM42682.1 - 0.014 15.0 3.8 0.83 9.2 0.3 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF2590 PF10761.9 GAM42682.1 - 0.015 15.4 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2590) UDPG_MGDP_dh_N PF03721.14 GAM42682.1 - 0.026 14.1 1.5 0.57 9.7 0.2 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 GAM42682.1 - 0.036 13.1 0.3 4 6.4 0.0 2.5 2 0 0 2 2 2 0 Lycopene cyclase protein DFP PF04127.15 GAM42682.1 - 0.042 13.7 0.2 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein TrkA_N PF02254.18 GAM42682.1 - 0.053 13.8 2.9 9.8 6.5 0.2 3.4 3 1 0 3 3 3 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 GAM42682.1 - 0.068 12.5 0.3 1.8 7.9 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 GAM42682.1 - 0.16 10.8 2.8 0.85 8.4 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 GAM42682.1 - 1.1 8.9 3.5 9.6 5.8 0.4 2.7 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DAO PF01266.24 GAM42683.1 - 2.7e-34 119.3 0.2 3.4e-34 119.0 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM42683.1 - 0.0013 18.9 0.3 0.0084 16.3 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM42683.1 - 0.012 14.8 0.4 0.17 11.1 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM42683.1 - 0.11 11.7 0.2 0.26 10.5 0.2 1.5 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.6 GAM42683.1 - 0.17 11.0 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAM42683.1 - 0.19 11.7 0.2 1.2 9.1 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.16 GAM42684.1 - 5.4e-15 55.2 21.1 7e-15 54.8 21.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.6 GAM42684.1 - 0.15 11.7 1.4 0.34 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ytp1 PF10355.9 GAM42685.1 - 8.8e-94 313.8 11.6 1.6e-93 313.0 11.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 GAM42685.1 - 2.6e-27 94.7 2.0 2.6e-27 94.7 2.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF1700 PF08006.11 GAM42685.1 - 0.093 12.3 0.1 0.093 12.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) Pectate_lyase_3 PF12708.7 GAM42686.1 - 2.4e-104 347.8 20.2 1.3e-88 296.4 7.7 3.1 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 GAM42686.1 - 3.8e-08 32.9 2.8 0.0017 18.0 0.2 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase FMO-like PF00743.19 GAM42687.1 - 3.4e-12 45.6 0.1 1.1e-11 43.9 0.0 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAM42687.1 - 2e-10 40.4 0.0 1.4e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM42687.1 - 2.3e-10 40.6 0.0 7.4e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAM42687.1 - 2.4e-10 40.1 0.0 3.4e-07 29.7 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAM42687.1 - 3e-09 36.6 0.0 7.4e-08 32.0 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM42687.1 - 1.8e-05 24.8 1.6 0.00084 19.3 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 GAM42687.1 - 0.1 12.7 0.6 19 5.3 0.0 3.9 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 GAM42687.1 - 0.12 11.6 0.0 0.38 9.9 0.0 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 GAM42688.1 - 1.5e-64 218.4 0.0 1.5e-63 215.2 0.0 2.4 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAM42688.1 - 9.4e-28 97.3 0.0 1.7e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.10 GAM42688.1 - 0.0019 17.3 0.0 0.078 12.0 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 GAM42688.1 - 0.021 15.1 0.1 0.069 13.4 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM42688.1 - 0.047 12.9 0.0 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM42688.1 - 0.057 12.1 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_4 PF01565.23 GAM42689.1 - 3.1e-24 85.3 0.0 6.2e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 GAM42689.1 - 2.8e-14 53.4 0.0 4.1e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain ADH_zinc_N PF00107.26 GAM42690.1 - 1.5e-25 89.7 0.1 2.6e-25 88.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAM42690.1 - 1.8e-11 43.9 0.0 3.2e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N PF08240.12 GAM42690.1 - 7.7e-11 41.8 0.0 1.9e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 GAM42690.1 - 2.3e-05 23.8 0.5 3.9e-05 23.1 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 GAM42690.1 - 4.2e-05 24.6 0.1 0.00082 20.4 0.0 2.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 GAM42690.1 - 0.022 14.5 1.1 0.9 9.2 0.2 2.2 1 1 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF4072 PF13284.6 GAM42690.1 - 0.075 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) Fungal_trans PF04082.18 GAM42691.1 - 8.1e-08 31.6 0.0 1.7e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cation_efflux PF01545.21 GAM42693.1 - 2.1e-15 57.0 7.0 2.7e-15 56.6 7.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAM42693.1 - 2.6e-10 40.3 0.2 6.1e-10 39.1 0.2 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter GAT PF03127.14 GAM42694.1 - 1.1e-14 54.5 0.7 1.1e-14 54.5 0.7 1.7 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 GAM42694.1 - 0.00021 21.2 0.0 0.00043 20.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain Syntaxin_2 PF14523.6 GAM42694.1 - 0.044 14.1 0.2 0.086 13.2 0.2 1.5 1 0 0 1 1 1 0 Syntaxin-like protein Ribosomal_L22 PF00237.19 GAM42695.1 - 2.7e-41 140.0 0.1 4.2e-41 139.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e 2-Hacid_dh_C PF02826.19 GAM42696.1 - 2.2e-55 186.8 0.0 3e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAM42696.1 - 5.7e-12 45.5 0.0 7.2e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAM42696.1 - 0.00087 19.5 0.1 0.0022 18.2 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 GAM42696.1 - 0.067 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_N PF08240.12 GAM42697.1 - 1.5e-27 95.6 0.1 2.6e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 GAM42697.1 - 3e-13 49.8 0.6 1e-06 28.4 0.0 2.2 1 1 1 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 GAM42697.1 - 6.2e-13 48.9 1.3 1.3e-12 47.8 0.1 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ApbA PF02558.16 GAM42697.1 - 0.05 13.2 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 GAM42697.1 - 0.053 13.8 0.1 0.14 12.4 0.1 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 GAM42698.1 - 3.3e-46 157.8 0.1 3.7e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM42698.1 - 2.9e-44 150.9 0.1 3.7e-44 150.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM42698.1 - 7.5e-11 42.3 0.1 1.1e-10 41.8 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM42698.1 - 1.5e-05 24.6 0.0 3e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM42698.1 - 6.6e-05 22.5 0.1 9.9e-05 21.9 0.1 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAM42698.1 - 0.00016 21.6 0.0 0.00043 20.2 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAM42698.1 - 0.0074 15.5 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAM42698.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ACT PF01842.25 GAM42698.1 - 0.14 12.0 0.1 11 5.9 0.0 2.4 2 0 0 2 2 2 0 ACT domain Fungal_trans PF04082.18 GAM42699.1 - 1.6e-07 30.6 0.1 2.3e-06 26.8 0.1 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM42699.1 - 0.0034 17.5 2.9 0.0067 16.5 2.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 GAM42700.1 - 4.2e-55 186.9 0.3 5.3e-55 186.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM42700.1 - 8.1e-52 175.5 0.7 1.2e-51 175.0 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAM42700.1 - 1.1e-09 38.5 0.3 1.7e-09 37.8 0.3 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM42700.1 - 5.7e-08 32.5 0.0 7.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM42700.1 - 0.00025 20.5 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAM42700.1 - 0.00078 18.6 0.3 0.0029 16.7 0.1 2.0 2 1 0 2 2 2 1 RmlD substrate binding domain ADH_zinc_N PF00107.26 GAM42700.1 - 0.0017 18.3 0.1 0.0041 17.1 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 GAM42700.1 - 0.0081 16.6 0.1 0.071 13.6 0.1 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Glyco_transf_5 PF08323.11 GAM42700.1 - 0.033 13.9 0.0 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 Starch synthase catalytic domain THF_DHG_CYH_C PF02882.19 GAM42700.1 - 0.052 12.9 0.1 0.12 11.7 0.1 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 GAM42700.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_transf_4 PF13439.6 GAM42700.1 - 0.18 11.8 0.0 5.5 7.0 0.0 2.5 2 1 1 3 3 3 0 Glycosyltransferase Family 4 Ferric_reduct PF01794.19 GAM42701.1 - 2.1e-24 86.0 9.3 5.8e-24 84.6 9.3 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAM42701.1 - 7.7e-14 52.1 0.1 1.6e-11 44.6 0.1 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAM42701.1 - 2.4e-10 40.5 0.2 2.7e-05 24.2 0.2 2.5 2 0 0 2 2 2 2 FAD-binding domain DUF4271 PF14093.6 GAM42701.1 - 1.5 8.7 7.3 1.7 8.5 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) CASP_C PF08172.12 GAM42702.1 - 9.1e-90 300.4 1.1 9.1e-90 300.4 1.1 3.8 2 1 2 4 4 4 1 CASP C terminal TPR_MLP1_2 PF07926.12 GAM42702.1 - 0.0063 16.6 7.2 0.0063 16.6 7.2 6.6 5 2 2 7 7 7 1 TPR/MLP1/MLP2-like protein betaPIX_CC PF16523.5 GAM42702.1 - 0.049 13.5 16.1 0.13 12.1 2.3 4.4 3 1 0 3 3 3 0 betaPIX coiled coil FliD_C PF07195.12 GAM42702.1 - 0.76 9.2 22.4 0.043 13.2 2.8 4.0 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 C-terminus PT-VENN PF04829.13 GAM42702.1 - 0.76 9.9 6.9 1.4 9.1 4.7 2.5 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif K_channel_TID PF07941.11 GAM42702.1 - 0.86 10.1 12.0 1.8 9.0 6.7 2.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF3037 PF11236.8 GAM42702.1 - 4.5 7.7 7.2 3.9 7.9 1.4 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF3037) NAD_binding_1 PF00175.21 GAM42702.1 - 4.6 7.9 6.8 2.5 8.8 0.0 3.4 4 0 0 4 4 4 0 Oxidoreductase NAD-binding domain Vps39_2 PF10367.9 GAM42703.1 - 1.7e-08 34.8 0.0 3.2e-07 30.8 0.0 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 GAM42703.1 - 0.00046 20.4 0.2 0.014 15.7 0.0 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Dioxygenase_C PF00775.21 GAM42704.1 - 2.1e-43 147.9 0.0 2.9e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 GAM42704.1 - 1e-31 108.6 0.0 1.9e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 GAM42704.1 - 0.12 12.7 0.0 0.64 10.3 0.0 2.1 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Zn_clus PF00172.18 GAM42705.1 - 0.027 14.6 9.7 0.06 13.5 9.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.22 GAM42706.1 - 3e-20 71.7 0.2 3.9e-20 71.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAM42706.1 - 0.02 15.0 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Pan3_PK PF18101.1 GAM42707.1 - 1.9e-63 212.5 0.8 3e-63 211.9 0.8 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 GAM42707.1 - 1.1e-06 28.2 0.0 1.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM42707.1 - 0.018 14.4 0.1 0.027 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase UBA_4 PF14555.6 GAM42708.1 - 4.7e-13 48.7 0.0 1.1e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 GAM42708.1 - 1.8e-09 37.7 0.0 5.5e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 UBX domain BAF1_ABF1 PF04684.13 GAM42708.1 - 0.042 12.9 1.5 0.06 12.4 1.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1682 PF07946.14 GAM42708.1 - 0.17 11.1 8.2 0.29 10.3 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Peptidase_M16 PF00675.20 GAM42709.1 - 4.6e-56 189.0 0.5 9.9e-56 187.9 0.5 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAM42709.1 - 3e-36 125.1 0.0 4.3e-35 121.4 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Epimerase PF01370.21 GAM42710.1 - 1.5e-19 70.4 0.0 1.9e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM42710.1 - 1.2e-12 47.5 0.0 1.5e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM42710.1 - 1.1e-07 31.6 0.0 2.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAM42710.1 - 6.4e-05 22.2 0.0 0.0001 21.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 GAM42710.1 - 0.0011 19.3 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 GAM42710.1 - 0.0027 16.9 0.0 0.2 10.8 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 GAM42710.1 - 0.0027 17.2 0.0 0.025 14.1 0.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 GAM42710.1 - 0.0059 15.8 0.0 0.02 14.0 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 GAM42710.1 - 0.007 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Cytochrome-c551 PF10643.9 GAM42710.1 - 0.18 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 FAD_binding_3 PF01494.19 GAM42711.1 - 3.9e-18 65.8 0.1 9.9e-11 41.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAM42711.1 - 1e-06 28.2 0.1 0.0034 16.7 0.3 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM42711.1 - 2e-06 27.9 0.5 4.6e-06 26.8 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM42711.1 - 2.7e-06 27.2 0.7 0.0058 16.2 0.9 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM42711.1 - 6e-06 25.6 0.8 0.0052 15.9 2.3 2.2 1 1 1 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 GAM42711.1 - 0.0028 18.2 0.1 0.3 11.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 GAM42711.1 - 0.0039 16.6 0.1 0.0074 15.7 0.1 1.5 1 0 0 1 1 1 1 ThiF family Trp_halogenase PF04820.14 GAM42711.1 - 0.0063 15.4 0.1 0.0091 14.9 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 GAM42711.1 - 0.026 13.8 0.3 0.053 12.7 0.3 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 GAM42711.1 - 0.045 13.0 0.5 0.45 9.7 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cytotoxic PF09000.10 GAM42711.1 - 0.053 13.9 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Cytotoxic FAD_oxidored PF12831.7 GAM42711.1 - 0.09 12.1 0.4 0.24 10.7 0.4 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 GAM42711.1 - 0.12 11.4 0.4 0.2 10.7 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fibrillarin PF01269.17 GAM42712.1 - 1.4e-104 348.2 0.0 1.7e-104 347.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 GAM42712.1 - 2.8e-06 27.2 0.1 5.2e-06 26.3 0.1 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 GAM42712.1 - 0.021 14.4 0.0 0.05 13.2 0.0 1.6 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 GAM42712.1 - 0.036 13.8 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HET PF06985.11 GAM42713.1 - 0.00039 20.8 0.1 0.02 15.2 0.1 2.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 GAM42714.1 - 8e-77 253.9 12.1 4e-13 49.7 0.2 5.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM42714.1 - 6.7e-54 179.6 0.5 2e-12 47.4 0.0 7.3 4 1 3 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 GAM42714.1 - 2.6e-43 144.6 6.4 2.3e-05 24.6 0.0 10.8 11 0 0 11 11 11 10 Ankyrin repeat Ank_3 PF13606.6 GAM42714.1 - 2.3e-41 135.1 0.0 0.0067 16.8 0.0 11.2 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 GAM42714.1 - 7.4e-39 131.3 1.9 2.5e-05 24.5 0.0 7.6 4 2 3 7 7 7 7 Ankyrin repeats (many copies) BiPBP_C PF06832.12 GAM42714.1 - 0.14 12.2 0.0 2.3 8.3 0.0 2.9 3 2 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family F-box-like PF12937.7 GAM42714.1 - 0.21 11.5 2.0 0.26 11.2 0.5 2.0 2 0 0 2 2 2 0 F-box-like DUF3455 PF11937.8 GAM42715.1 - 1e-45 156.0 0.8 1.3e-45 155.6 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 GAM42715.1 - 4.4e-19 68.4 0.7 4.4e-19 68.4 0.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2990) ADH_N_2 PF16884.5 GAM42716.1 - 6.1e-22 77.6 0.0 9.8e-22 76.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 GAM42716.1 - 6.7e-22 77.9 0.0 9.7e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM42716.1 - 3.1e-13 50.9 0.0 6.2e-13 49.9 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 GAM42716.1 - 0.011 15.5 0.0 0.25 11.1 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2855) CybS PF05328.12 GAM42717.1 - 3.7e-50 169.1 0.0 5.1e-50 168.6 0.0 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Maf PF02545.14 GAM42718.1 - 3.4e-45 153.9 0.0 4.3e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein zinc_ribbon_2 PF13240.6 GAM42719.1 - 0.024 14.3 0.7 0.058 13.1 0.7 1.6 1 0 0 1 1 1 0 zinc-ribbon domain GFA PF04828.14 GAM42719.1 - 0.031 14.6 0.0 0.064 13.6 0.0 1.7 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme HLH PF00010.26 GAM42720.1 - 2.7e-08 33.6 0.0 5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.12 GAM42720.1 - 0.0077 15.6 0.1 0.0088 15.4 0.1 1.2 1 0 0 1 1 1 1 Umbravirus long distance movement (LDM) family Med9 PF07544.13 GAM42720.1 - 0.017 15.2 0.3 0.038 14.1 0.1 1.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 MIG-14_Wnt-bd PF06664.12 GAM42722.1 - 0.0018 17.6 12.2 0.0025 17.1 12.2 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Fungal_trans_2 PF11951.8 GAM42723.1 - 1.7e-11 43.6 2.0 5e-11 42.0 2.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM42723.1 - 3.3e-08 33.5 9.4 6.2e-08 32.6 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_2 PF13519.6 GAM42723.1 - 0.00063 20.4 0.0 0.0048 17.5 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 GAM42723.1 - 0.016 15.5 0.0 0.065 13.5 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain PNP_UDP_1 PF01048.20 GAM42724.1 - 2.6e-09 36.7 0.0 7.7e-09 35.1 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.6 GAM42724.1 - 0.00015 22.2 0.1 0.0019 18.6 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 GAM42724.1 - 0.00026 21.0 0.1 0.00086 19.3 0.1 1.8 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 GAM42724.1 - 0.00049 19.4 1.4 0.083 12.1 0.1 2.2 1 1 1 2 2 2 2 KAP family P-loop domain AAA_22 PF13401.6 GAM42724.1 - 0.016 15.5 0.1 0.11 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAM42724.1 - 0.033 14.6 0.2 0.33 11.3 0.0 2.7 4 0 0 4 4 4 0 RNA helicase AAA PF00004.29 GAM42724.1 - 0.086 13.3 0.1 0.41 11.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAM42724.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ANAPC4 PF12896.7 GAM42726.1 - 3e-69 232.6 2.3 4.3e-69 232.1 2.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 GAM42726.1 - 4.4e-30 103.8 0.0 1.8e-29 101.9 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain YkuI_C PF10388.9 GAM42726.1 - 0.022 14.6 0.2 1.6 8.6 0.0 2.7 3 0 0 3 3 3 0 EAL-domain associated signalling protein domain HEAT_EZ PF13513.6 GAM42727.1 - 6.3e-12 45.7 10.7 2.8e-08 34.1 0.0 6.9 8 0 0 8 8 8 2 HEAT-like repeat HEAT PF02985.22 GAM42727.1 - 7.8e-12 44.4 13.1 3.6e-05 23.7 0.1 8.2 8 1 0 8 8 8 3 HEAT repeat IBN_N PF03810.19 GAM42727.1 - 8.8e-09 35.2 3.5 3.5e-08 33.3 0.2 3.7 5 0 0 5 5 5 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 GAM42727.1 - 9.5e-08 32.3 14.8 0.0008 19.7 0.1 6.9 4 2 1 7 7 7 2 HEAT repeats CLASP_N PF12348.8 GAM42727.1 - 7.8e-05 22.3 1.8 0.081 12.5 0.0 4.3 3 1 0 4 4 4 1 CLASP N terminal HEAT_PBS PF03130.16 GAM42727.1 - 0.041 14.5 0.1 94 4.1 0.0 5.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DUF3338 PF11819.8 GAM42727.1 - 0.08 12.9 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) Ribosomal_S8 PF00410.19 GAM42728.1 - 5.1e-21 74.9 0.1 7.6e-21 74.4 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.22 GAM42729.1 - 1.1e-13 51.4 0.0 6.9e-12 45.5 0.0 2.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Lactamase_B_2 PF12706.7 GAM42730.1 - 1.3e-11 44.4 0.0 2.4e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAM42730.1 - 3.1e-09 36.9 0.0 6.8e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ubiquitin PF00240.23 GAM42732.1 - 1.5e-07 31.1 0.0 5.7e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 GAM42732.1 - 0.014 15.9 0.0 0.051 14.1 0.0 2.0 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAM42732.1 - 0.02 15.0 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like PS_Dcarbxylase PF02666.15 GAM42733.1 - 1.5e-77 259.7 0.0 1.6e-76 256.3 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase ANAPC10 PF03256.16 GAM42733.1 - 2.9e-41 141.2 0.0 4.9e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) DUF1206 PF06724.11 GAM42733.1 - 0.094 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) CAP_N PF01213.19 GAM42733.1 - 6.1 6.2 8.4 11 5.3 8.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Iso_dh PF00180.20 GAM42734.1 - 5.4e-125 417.2 0.0 6.1e-125 417.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CDP-OH_P_transf PF01066.21 GAM42735.1 - 9.2e-13 48.8 0.5 9.2e-13 48.8 0.5 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ABC_tran PF00005.27 GAM42736.1 - 3.5e-49 166.8 3.8 5.8e-27 94.9 0.0 3.4 3 0 0 3 3 3 2 ABC transporter PP2C PF00481.21 GAM42736.1 - 3.4e-32 112.1 0.0 1.9e-26 93.3 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C ABC_membrane PF00664.23 GAM42736.1 - 8.3e-23 81.4 30.3 1.1e-20 74.5 10.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GAM42736.1 - 4.6e-09 36.0 4.0 0.4 10.1 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM42736.1 - 9.9e-09 34.8 0.4 0.0058 16.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM42736.1 - 1.1e-07 31.9 0.3 0.0034 17.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 GAM42736.1 - 1.5e-06 28.6 0.2 0.017 15.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 GAM42736.1 - 7.1e-05 23.4 14.9 0.021 15.3 0.1 3.7 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 GAM42736.1 - 0.00012 22.1 3.7 0.36 10.6 0.0 4.4 5 1 0 6 6 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAM42736.1 - 0.00016 21.5 3.4 0.075 12.7 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.6 GAM42736.1 - 0.00018 21.9 0.7 0.6 10.5 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 GAM42736.1 - 0.00041 20.4 0.0 1 9.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase NB-ARC PF00931.22 GAM42736.1 - 0.00076 18.7 0.4 1.3 8.1 0.0 3.2 3 1 0 3 3 2 1 NB-ARC domain AAA_33 PF13671.6 GAM42736.1 - 0.00089 19.4 0.0 1.4 9.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 GAM42736.1 - 0.0019 17.8 0.7 4 7.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 GAM42736.1 - 0.0021 17.2 0.1 1.7 7.6 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein ATG16 PF08614.11 GAM42736.1 - 0.0022 18.3 16.3 0.005 17.1 16.0 1.7 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) RNA_helicase PF00910.22 GAM42736.1 - 0.0022 18.3 0.1 3.3 8.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 GAM42736.1 - 0.0029 17.0 0.5 0.12 11.7 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 GAM42736.1 - 0.0036 17.1 0.7 2.4 7.9 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.6 GAM42736.1 - 0.0038 17.8 0.0 1.1 9.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 GAM42736.1 - 0.0039 17.3 5.1 0.8 9.7 0.0 3.8 3 0 0 3 3 3 1 Dynamin family Rad17 PF03215.15 GAM42736.1 - 0.0049 16.8 0.7 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain ATP-synt_ab PF00006.25 GAM42736.1 - 0.0052 16.5 0.0 0.56 9.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain zf-C4H2 PF10146.9 GAM42736.1 - 0.0063 16.8 0.3 0.015 15.6 0.3 1.6 1 0 0 1 1 1 1 Zinc finger-containing protein Roc PF08477.13 GAM42736.1 - 0.0077 16.4 0.1 8 6.7 0.0 3.2 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 GAM42736.1 - 0.0086 16.0 0.1 0.28 11.1 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea PRK PF00485.18 GAM42736.1 - 0.0091 15.8 1.7 0.24 11.1 0.1 3.1 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 GAM42736.1 - 0.0097 15.4 0.1 0.96 8.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 GAM42736.1 - 0.018 15.1 0.0 0.38 10.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 GAM42736.1 - 0.019 15.0 0.1 8.6 6.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 GAM42736.1 - 0.019 15.2 4.2 3.3 7.9 0.1 3.5 3 0 0 3 3 2 0 AAA domain Adeno_IVa2 PF02456.15 GAM42736.1 - 0.028 13.2 0.9 0.061 12.1 0.1 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein NACHT PF05729.12 GAM42736.1 - 0.038 13.9 0.1 13 5.6 0.0 2.8 2 0 0 2 2 2 0 NACHT domain Septin PF00735.18 GAM42736.1 - 0.047 13.0 0.0 0.54 9.5 0.0 2.2 2 0 0 2 2 2 0 Septin cobW PF02492.19 GAM42736.1 - 0.05 13.2 0.5 0.92 9.1 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 GAM42736.1 - 0.059 13.8 0.0 5.4 7.4 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAM42736.1 - 0.063 13.0 0.2 7.2 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 GAM42736.1 - 0.074 12.8 0.2 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 GAM42736.1 - 0.08 12.7 1.0 8.5 6.1 0.1 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 GAM42736.1 - 0.11 12.8 0.5 12 6.2 0.2 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fib_alpha PF08702.10 GAM42736.1 - 0.12 12.5 10.7 0.38 10.9 10.7 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PP2C_2 PF13672.6 GAM42736.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 2C FPP PF05911.11 GAM42736.1 - 0.13 10.4 10.0 0.23 9.6 10.0 1.3 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF4407 PF14362.6 GAM42736.1 - 0.15 11.4 7.1 0.35 10.2 7.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) G-alpha PF00503.20 GAM42736.1 - 0.16 11.1 2.0 12 5.0 0.0 2.7 3 0 0 3 3 2 0 G-protein alpha subunit AAA_13 PF13166.6 GAM42736.1 - 0.2 10.3 7.7 0.41 9.2 7.7 1.4 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 GAM42736.1 - 0.23 10.3 15.0 0.45 9.3 15.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 GAM42736.1 - 0.97 8.9 7.7 2.2 7.8 7.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.8 GAM42736.1 - 1 6.8 15.3 1.3 6.4 14.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ABC_ATPase PF09818.9 GAM42736.1 - 2 7.1 9.1 3.7 6.2 0.0 4.1 5 0 0 5 5 4 0 Predicted ATPase of the ABC class Bacillus_HBL PF05791.11 GAM42736.1 - 2 8.2 5.7 1.3 8.8 0.6 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FAM76 PF16046.5 GAM42736.1 - 2.1 7.7 7.5 4.8 6.4 7.5 1.6 1 0 0 1 1 1 0 FAM76 protein DUF3552 PF12072.8 GAM42736.1 - 2.3 7.6 18.2 6.4 6.1 17.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF16 PF01519.16 GAM42736.1 - 3.3 8.2 12.7 1.4 9.5 4.4 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 BRE1 PF08647.11 GAM42736.1 - 3.7 7.7 11.6 15 5.7 11.6 2.1 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase HMMR_N PF15905.5 GAM42736.1 - 4.2 6.8 13.7 7.5 5.9 13.7 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Atg14 PF10186.9 GAM42736.1 - 4.9 6.1 15.0 9 5.3 15.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 GAM42736.1 - 7.2 6.7 10.5 6 6.9 7.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 GAM42736.1 - 7.6 7.0 20.9 2.7 8.4 17.3 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) RRM_1 PF00076.22 GAM42737.1 - 1.3e-42 143.4 0.5 1.9e-20 72.4 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 GAM42737.1 - 1.2e-23 84.0 0.1 3.6e-23 82.5 0.1 1.9 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 GAM42737.1 - 2.5e-05 24.1 0.0 0.042 13.7 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 GAM42737.1 - 0.007 16.4 0.0 0.024 14.7 0.0 1.9 1 0 0 1 1 1 1 RNA binding motif PHM7_cyt PF14703.6 GAM42737.1 - 0.014 15.7 0.0 3.7 7.8 0.0 3.1 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 GAM42737.1 - 0.059 13.5 0.1 2 8.6 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 GAM42737.1 - 0.091 12.4 0.0 0.93 9.1 0.0 2.1 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.28 GAM42738.1 - 3.3e-19 68.8 0.2 3.3e-19 68.8 0.2 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 GAM42738.1 - 1.3e-13 51.5 16.3 2.4e-13 50.6 16.1 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 GAM42738.1 - 0.13 12.5 0.3 0.27 11.4 0.3 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region COX14 PF14880.6 GAM42738.1 - 0.27 11.1 2.8 0.25 11.2 0.6 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Fungal_trans PF04082.18 GAM42740.1 - 3.1e-20 72.3 0.9 4.9e-20 71.7 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_2 PF04909.14 GAM42741.1 - 1.5e-21 77.5 0.0 4.9e-21 75.8 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase Adap_comp_sub PF00928.21 GAM42743.1 - 2.7e-19 69.6 0.1 3.6e-19 69.2 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAM42743.1 - 1e-06 28.7 0.1 1.7e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 GAM42743.1 - 0.00052 20.4 0.2 0.0011 19.4 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) muHD PF10291.9 GAM42743.1 - 0.0072 15.8 0.0 0.022 14.2 0.0 1.7 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain Mg_trans_NIPA PF05653.14 GAM42744.1 - 7.3e-75 251.8 5.6 9.7e-75 251.4 5.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA DUF2420 PF10336.9 GAM42744.1 - 1.3e-21 76.7 0.0 2.7e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) EamA PF00892.20 GAM42744.1 - 0.00015 22.0 5.3 0.00015 22.0 5.3 2.1 2 0 0 2 2 2 1 EamA-like transporter family Mg_trans_NIPA PF05653.14 GAM42745.1 - 1.6e-08 34.0 1.2 1.9e-08 33.8 1.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Syja_N PF02383.18 GAM42747.1 - 7.7e-92 308.0 0.3 1.3e-91 307.3 0.0 1.5 2 0 0 2 2 2 1 SacI homology domain hSac2 PF12456.8 GAM42747.1 - 2.3e-40 136.9 0.0 4.7e-40 135.9 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase HEAT_EZ PF13513.6 GAM42748.1 - 9.3e-40 134.6 5.4 2.1e-16 60.1 0.0 10.1 9 2 1 10 10 10 5 HEAT-like repeat HEAT PF02985.22 GAM42748.1 - 7.8e-30 100.4 12.0 8.5e-06 25.6 0.0 11.5 12 0 0 12 12 10 5 HEAT repeat HEAT_2 PF13646.6 GAM42748.1 - 3.3e-22 78.7 1.3 0.0014 18.9 0.0 8.9 6 3 3 9 9 9 5 HEAT repeats Cnd1 PF12717.7 GAM42748.1 - 1.4e-15 57.7 0.2 4.6e-05 23.5 0.0 5.3 4 1 0 4 4 4 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 GAM42748.1 - 1.1e-09 38.8 0.1 0.38 11.4 0.0 6.9 4 2 4 8 8 8 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 GAM42748.1 - 1.2e-08 34.9 0.0 1.9 8.0 0.1 6.6 4 3 2 6 6 6 3 CLASP N terminal Adaptin_N PF01602.20 GAM42748.1 - 3.8e-08 32.4 0.1 0.0011 17.6 0.0 4.0 2 2 1 4 4 4 2 Adaptin N terminal region Arm PF00514.23 GAM42748.1 - 8e-08 32.1 2.2 0.39 10.8 0.0 6.5 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 GAM42748.1 - 1.2e-06 27.9 5.8 0.066 12.3 0.2 5.5 6 0 0 6 6 6 2 RNAPII transcription regulator C-terminal IBN_N PF03810.19 GAM42748.1 - 2.9e-06 27.1 0.2 0.15 12.0 0.0 5.2 3 1 1 4 4 4 1 Importin-beta N-terminal domain DRIM PF07539.12 GAM42748.1 - 4.1e-05 22.1 0.0 0.022 13.1 0.0 4.0 3 1 0 4 4 4 1 Down-regulated in metastasis RIX1 PF08167.12 GAM42748.1 - 0.0024 17.6 0.1 3.6 7.3 0.0 4.5 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis DUF3437 PF11919.8 GAM42748.1 - 0.0027 17.6 0.1 0.55 10.2 0.0 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) Tti2 PF10521.9 GAM42748.1 - 0.0053 16.3 0.3 21 4.5 0.0 4.3 2 2 3 5 5 5 0 Tti2 family Dopey_N PF04118.14 GAM42748.1 - 0.012 14.7 1.3 0.43 9.7 0.0 2.9 2 1 1 3 3 3 0 Dopey, N-terminal TIP120 PF08623.10 GAM42748.1 - 0.13 12.1 0.3 18 5.0 0.0 4.1 5 0 0 5 5 5 0 TATA-binding protein interacting (TIP20) Bac_luciferase PF00296.20 GAM42749.1 - 2.7e-58 197.9 0.0 3.9e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.17 GAM42750.1 - 2.5e-07 29.9 12.1 2.5e-07 29.9 12.1 1.9 1 1 1 2 2 2 1 Sodium:solute symporter family VirC2 PF07181.11 GAM42750.1 - 0.18 11.2 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 VirC2 protein FMO-like PF00743.19 GAM42751.1 - 3.8e-15 55.3 0.1 4.8e-13 48.4 0.1 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 GAM42751.1 - 3.2e-14 52.9 0.0 8.3e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM42751.1 - 1.7e-08 34.1 0.2 1e-06 28.2 0.0 3.0 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM42751.1 - 1.5e-07 31.0 0.0 1.2e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM42751.1 - 7.1e-07 29.1 0.1 9.1e-06 25.5 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM42751.1 - 4e-05 23.6 0.1 0.0004 20.4 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 GAM42751.1 - 9.5e-05 21.8 0.0 0.43 9.9 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 GAM42751.1 - 0.00016 21.0 0.0 0.002 17.4 0.0 2.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 GAM42751.1 - 0.0054 16.0 0.2 0.012 14.8 0.1 1.6 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 GAM42751.1 - 0.12 11.4 0.4 9.6 5.2 0.1 2.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 GAM42751.1 - 0.13 12.3 0.1 27 4.8 0.0 3.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 GAM42751.1 - 0.19 11.0 0.0 0.65 9.2 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 GAM42751.1 - 0.24 10.6 0.2 0.38 9.9 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N PF00107.26 GAM42752.1 - 1.1e-07 31.9 0.2 2.3e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM42752.1 - 0.00012 21.9 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM42752.1 - 0.0058 17.7 0.0 0.017 16.2 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans_2 PF11951.8 GAM42753.1 - 1.5e-06 27.3 1.3 2.4e-06 26.6 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain IL34 PF15036.6 GAM42753.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Interleukin 34 Peptidase_C12 PF01088.21 GAM42754.1 - 1.6e-69 233.9 0.0 1.9e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 GAM42754.1 - 2e-08 34.0 0.0 2e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases Choline_kinase PF01633.20 GAM42755.1 - 2.5e-56 190.6 0.0 4.8e-56 189.7 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 GAM42755.1 - 2.5e-17 62.3 0.0 6e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 GAM42755.1 - 2.5e-05 24.3 0.6 2.5e-05 24.3 0.6 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family YopH_N PF09013.10 GAM42755.1 - 0.17 12.1 0.1 0.4 11.0 0.1 1.6 1 0 0 1 1 1 0 YopH, N-terminal Mem_trans PF03547.18 GAM42756.1 - 1.9e-55 187.8 0.0 2.7e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Membrane transport protein APH PF01636.23 GAM42756.1 - 0.00017 21.6 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAM42757.1 - 6.4e-55 186.3 0.0 3.6e-52 177.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM42757.1 - 1.5e-31 109.6 0.0 1e-30 106.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 GAM42757.1 - 0.0023 17.1 0.1 0.0037 16.4 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 GAM42757.1 - 0.0035 16.7 0.0 0.0052 16.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAM42757.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pyr_redox_2 PF07992.14 GAM42758.1 - 4e-54 183.9 1.1 6.3e-54 183.2 1.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAM42758.1 - 2.6e-30 104.9 0.6 4.6e-30 104.1 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAM42758.1 - 1.1e-14 54.8 0.3 1.1e-14 54.8 0.3 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM42758.1 - 5.8e-10 38.9 2.0 1.1e-08 34.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM42758.1 - 0.00041 19.6 0.0 0.00065 18.9 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 GAM42758.1 - 0.013 15.4 0.2 0.013 15.4 0.2 2.5 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 GAM42758.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 GAM42758.1 - 0.33 10.0 5.0 0.36 9.9 1.6 2.4 2 1 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.16 GAM42759.1 - 1.7e-36 125.9 20.9 2.1e-36 125.6 20.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ECH_1 PF00378.20 GAM42760.1 - 1.6e-39 135.7 0.0 2.5e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM42760.1 - 1.7e-22 80.4 0.0 2.6e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CorA PF01544.18 GAM42760.1 - 8e-06 25.4 6.9 1.5e-05 24.5 6.6 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_64 PF16483.5 GAM42762.1 - 7.3e-119 397.3 0.1 8.6e-119 397.1 0.1 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Pes-10 PF07149.11 GAM42763.1 - 5.5 5.9 10.7 7.4 5.5 10.7 1.1 1 0 0 1 1 1 0 Pes-10 ADH_N PF08240.12 GAM42764.1 - 1e-11 44.7 0.0 3.1e-11 43.1 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM42764.1 - 1.4e-11 45.5 0.0 3.4e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acetyltransf_10 PF13673.7 GAM42765.1 - 1.1e-07 31.8 0.0 2.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM42765.1 - 1.3e-07 31.9 0.0 5.4e-07 29.9 0.0 1.9 1 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM42765.1 - 0.00015 22.1 0.0 0.00026 21.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM42765.1 - 0.0017 18.3 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAM42765.1 - 0.011 15.7 0.1 0.22 11.6 0.0 2.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM42765.1 - 0.024 14.7 0.0 0.14 12.3 0.0 2.0 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase DUF4200 PF13863.6 GAM42766.1 - 0.003 17.9 1.6 0.0095 16.3 1.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) CCDC53 PF10152.9 GAM42766.1 - 0.028 14.8 4.8 0.15 12.5 0.6 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Jnk-SapK_ap_N PF09744.9 GAM42766.1 - 0.11 12.8 2.4 0.096 12.9 0.4 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 tRNA-synt_2b PF00587.25 GAM42767.1 - 1.2e-31 110.1 0.0 2e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAM42767.1 - 8.1e-05 22.7 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain p450 PF00067.22 GAM42769.1 - 7.6e-71 239.2 0.0 9.5e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_28 PF03033.20 GAM42770.1 - 1.5e-17 63.9 0.4 2.5e-10 40.5 0.1 2.6 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 GAM42770.1 - 7.3e-05 23.0 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 GAM42770.1 - 0.00067 18.6 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UIM PF02809.20 GAM42770.1 - 0.015 15.1 0.8 0.049 13.6 0.8 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif Glyco_tran_28_C PF04101.16 GAM42770.1 - 0.028 14.4 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain SMBP PF16785.5 GAM42770.1 - 4.9 7.4 8.2 0.59 10.4 3.2 2.0 2 0 0 2 2 2 0 Small metal-binding protein ADH_N PF08240.12 GAM42771.1 - 1e-27 96.2 2.4 2.5e-27 94.9 2.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM42771.1 - 4.2e-12 46.2 0.0 7.3e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAM42771.1 - 1.8e-05 24.3 0.4 0.1 12.1 0.1 3.2 3 0 0 3 3 3 3 Glucose dehydrogenase C-terminus Glyco_hydro_16 PF00722.21 GAM42772.1 - 3.7e-43 147.0 1.1 3.7e-43 147.0 1.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Fungal_trans_2 PF11951.8 GAM42772.1 - 7.6e-06 25.0 0.1 7.6e-06 25.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Abhydrolase_1 PF00561.20 GAM42773.1 - 1.8e-10 40.9 0.2 2.5e-10 40.4 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM42773.1 - 1.7e-07 30.8 0.0 2.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 ATP-synt_G PF04718.15 GAM42774.1 - 1.3e-36 125.4 0.6 3e-36 124.2 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DEAD PF00270.29 GAM42775.1 - 4.5e-26 91.7 0.4 7.7e-25 87.7 0.4 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM42775.1 - 7.8e-24 84.2 0.1 4.5e-23 81.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM42775.1 - 2.1e-06 27.9 0.0 1.5e-05 25.1 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 GAM42775.1 - 0.0019 17.1 0.1 0.022 13.6 0.1 2.1 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SNF2_N PF00176.23 GAM42775.1 - 0.011 14.5 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain T4SS-DNA_transf PF02534.14 GAM42775.1 - 0.025 13.4 0.0 0.025 13.4 0.0 2.8 4 0 0 4 4 4 0 Type IV secretory system Conjugative DNA transfer SbcCD_C PF13558.6 GAM42775.1 - 0.12 12.7 0.1 0.35 11.1 0.1 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Hamartin PF04388.12 GAM42775.1 - 0.76 8.4 12.7 0.096 11.3 8.1 1.7 2 0 0 2 2 2 0 Hamartin protein Bacillus_PapR PF05968.11 GAM42776.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacillus PapR protein Methyltransf_16 PF10294.9 GAM42777.1 - 2.2e-22 79.6 0.0 3.7e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GAM42777.1 - 0.0001 22.2 0.0 0.00021 21.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain VPS28 PF03997.12 GAM42778.1 - 2.6e-73 245.8 0.0 3e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Noc2 PF03715.13 GAM42779.1 - 4.1e-129 430.1 0.2 1.2e-128 428.5 0.0 1.9 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 GAM42779.1 - 0.025 12.8 0.0 0.025 12.8 0.0 3.4 2 2 1 3 3 3 0 Nop14-like family Glyco_hydro_18 PF00704.28 GAM42780.1 - 5.3e-25 88.8 0.4 9.5e-25 88.0 0.4 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 PT-VENN PF04829.13 GAM42780.1 - 0.61 10.2 3.7 0.29 11.2 0.6 2.2 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif CMD PF02627.20 GAM42781.1 - 0.0007 19.6 0.0 0.4 10.8 0.0 2.5 2 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family adh_short_C2 PF13561.6 GAM42782.1 - 2e-61 207.5 0.3 2.5e-61 207.2 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM42782.1 - 7.4e-48 162.6 1.2 9.2e-48 162.3 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM42782.1 - 0.00042 20.3 0.1 0.00064 19.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM42782.1 - 0.0031 17.0 0.1 0.012 15.1 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 GAM42782.1 - 0.035 14.0 0.3 0.07 13.0 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DLH PF01738.18 GAM42783.1 - 1.4e-20 73.8 0.0 1.7e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAM42783.1 - 0.13 11.7 1.7 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family MFS_1 PF07690.16 GAM42784.1 - 4.7e-28 98.1 29.4 6.2e-28 97.7 29.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 GAM42784.1 - 2.2e-06 26.8 10.6 2.2e-06 26.8 10.6 1.4 1 1 0 1 1 1 1 MFS_1 like family DUF485 PF04341.12 GAM42784.1 - 0.069 13.1 0.0 0.069 13.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Fungal_trans PF04082.18 GAM42785.1 - 1.9e-27 96.0 1.8 1.9e-27 96.0 1.8 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM42785.1 - 4.3e-09 36.3 9.2 1.3e-08 34.8 9.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dimerisation PF08100.11 GAM42785.1 - 0.05 13.6 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 Dimerisation domain MoaC PF01967.21 GAM42786.1 - 3e-45 153.7 0.3 7.9e-45 152.3 0.3 1.8 1 0 0 1 1 1 1 MoaC family ABC_tran PF00005.27 GAM42786.1 - 2.7e-44 151.0 0.1 1.1e-20 74.6 0.0 4.0 2 1 0 2 2 2 2 ABC transporter Mob_synth_C PF06463.13 GAM42786.1 - 3.6e-36 123.9 0.3 1.8e-35 121.7 0.0 2.4 3 0 0 3 3 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 GAM42786.1 - 3e-26 92.8 0.1 7.5e-26 91.5 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily AAA_21 PF13304.6 GAM42786.1 - 6.4e-15 55.7 3.7 0.0014 18.5 0.0 4.7 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM42786.1 - 9.7e-11 41.5 2.6 0.006 16.1 0.0 4.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 GAM42786.1 - 4.9e-08 32.9 3.0 1.6e-07 31.3 3.0 1.9 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 GAM42786.1 - 1.6e-06 28.2 0.2 0.07 13.2 0.0 3.6 4 0 0 4 4 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 GAM42786.1 - 3.9e-05 23.5 0.2 0.028 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 GAM42786.1 - 0.0001 22.0 6.1 0.0054 16.5 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain NACHT PF05729.12 GAM42786.1 - 0.00018 21.5 0.1 1.2 9.0 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_18 PF13238.6 GAM42786.1 - 0.00021 21.9 0.5 0.31 11.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain Fer4_12 PF13353.6 GAM42786.1 - 0.00065 20.0 0.0 0.0019 18.5 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain AAA_28 PF13521.6 GAM42786.1 - 0.00085 19.6 0.5 0.21 11.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAM42786.1 - 0.0014 18.9 0.4 2.6 8.3 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 GAM42786.1 - 0.002 18.6 17.3 0.16 12.5 0.1 3.5 3 1 0 3 3 2 2 AAA domain MeaB PF03308.16 GAM42786.1 - 0.0022 17.0 0.7 0.87 8.5 0.2 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 GAM42786.1 - 0.003 16.8 1.2 12 5.0 0.1 3.4 3 0 0 3 3 3 0 NB-ARC domain AAA_33 PF13671.6 GAM42786.1 - 0.0042 17.2 0.4 1.3 9.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM42786.1 - 0.0043 17.5 8.3 0.93 9.8 0.1 3.5 2 1 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.6 GAM42786.1 - 0.0049 16.9 0.8 5.9 6.9 0.0 3.5 4 1 0 4 4 2 0 AAA domain RNA_helicase PF00910.22 GAM42786.1 - 0.0051 17.2 0.4 9.3 6.7 0.0 3.3 3 0 0 3 3 3 0 RNA helicase RsgA_GTPase PF03193.16 GAM42786.1 - 0.0054 16.6 4.2 2.3 8.1 0.0 3.5 2 1 1 3 3 3 1 RsgA GTPase AAA_30 PF13604.6 GAM42786.1 - 0.0056 16.4 1.9 3.6 7.2 0.1 3.8 2 2 0 3 3 3 1 AAA domain AAA PF00004.29 GAM42786.1 - 0.015 15.7 1.0 2.4 8.6 0.0 3.5 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 GAM42786.1 - 0.022 14.8 0.2 5.6 7.0 0.1 2.8 2 0 0 2 2 2 0 Dynamin family Hairpins PF04877.12 GAM42786.1 - 0.024 14.3 1.7 0.029 14.0 0.3 1.9 2 0 0 2 2 1 0 HrpZ ATPase_2 PF01637.18 GAM42786.1 - 0.039 13.9 0.3 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 GAM42786.1 - 0.041 13.9 0.2 2.4 8.2 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) PRK PF00485.18 GAM42786.1 - 0.052 13.3 0.0 10 5.8 0.0 3.0 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 GAM42786.1 - 0.06 13.4 3.1 1.3 9.0 0.1 3.1 3 0 0 3 3 2 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 GAM42786.1 - 0.06 12.7 0.2 0.72 9.2 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 GAM42786.1 - 0.062 13.0 0.8 22 4.7 0.1 3.3 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase Keratin_2_head PF16208.5 GAM42786.1 - 0.075 13.2 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Keratin type II head AAA_17 PF13207.6 GAM42786.1 - 0.083 13.3 5.6 7 7.1 0.0 4.1 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.9 GAM42786.1 - 0.1 12.3 0.7 8.9 6.1 0.1 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 GAM42786.1 - 0.15 11.4 1.6 5.1 6.3 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin NTPase_1 PF03266.15 GAM42786.1 - 0.17 11.8 1.5 19 5.1 0.0 4.0 4 0 0 4 4 4 0 NTPase Thymidylate_kin PF02223.17 GAM42786.1 - 0.17 11.5 0.9 19 4.8 0.0 3.1 3 0 0 3 3 3 0 Thymidylate kinase BTB PF00651.31 GAM42787.1 - 7.1e-16 58.4 0.0 1.3e-14 54.4 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain Vps39_2 PF10367.9 GAM42787.1 - 0.012 16.1 0.5 0.042 14.3 0.3 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 FYVE PF01363.21 GAM42787.1 - 0.44 10.7 3.1 1.7 8.9 3.1 2.0 1 1 0 1 1 1 0 FYVE zinc finger Acetyltransf_3 PF13302.7 GAM42788.1 - 1.7e-14 54.7 0.0 2.3e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain bZIP_1 PF00170.21 GAM42790.1 - 1.4e-09 37.9 10.0 1.4e-09 37.9 10.0 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAM42790.1 - 0.00022 21.2 10.8 0.00022 21.2 10.8 2.9 3 0 0 3 3 3 1 Basic region leucine zipper PilO PF04350.13 GAM42790.1 - 0.053 13.7 0.3 0.053 13.7 0.3 2.4 2 0 0 2 2 2 0 Pilus assembly protein, PilO Noggin PF05806.12 GAM42790.1 - 2.3 8.1 5.0 4.2 7.2 4.3 1.7 1 1 0 1 1 1 0 Noggin adh_short PF00106.25 GAM42791.1 - 2.7e-38 131.4 0.1 2.7e-38 131.4 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42791.1 - 1e-27 97.2 0.2 1.6e-27 96.6 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM42791.1 - 3e-06 27.2 0.2 4.9e-06 26.6 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAM42791.1 - 0.0001 22.3 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM42791.1 - 0.00013 21.6 0.0 0.00032 20.3 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family Vma12 PF11712.8 GAM42791.1 - 0.036 14.1 0.6 0.061 13.4 0.6 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Epimerase PF01370.21 GAM42791.1 - 0.054 12.9 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Lactamase_B_4 PF13691.6 GAM42792.1 - 4.3e-22 77.6 0.0 9.6e-22 76.4 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 GAM42792.1 - 9e-12 44.9 0.1 6.7e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain T3SS_basalb_I PF17001.5 GAM42792.1 - 0.17 12.5 1.8 1 10.0 0.4 3.0 4 0 0 4 4 4 0 Type III secretion basal body protein I, YscI, HrpB, PscI Zn_clus PF00172.18 GAM42792.1 - 1.4 9.1 14.6 2.5 8.3 14.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DSBA PF01323.20 GAM42793.1 - 1.3e-22 80.5 0.0 8.5e-16 58.3 0.0 2.1 1 1 0 2 2 2 2 DSBA-like thioredoxin domain DUF2379 PF09543.10 GAM42793.1 - 0.031 14.5 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) TipAS PF07739.13 GAM42793.1 - 0.11 13.1 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain WD40 PF00400.32 GAM42794.1 - 2.5e-50 167.4 17.1 3.2e-09 37.3 0.6 8.4 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM42794.1 - 2.9e-11 43.5 0.1 0.00033 20.9 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM42794.1 - 9.3e-08 31.2 0.6 0.0002 20.1 0.0 3.9 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAM42794.1 - 0.0048 15.7 0.0 3.5 6.3 0.0 2.8 2 1 0 3 3 3 2 Nup133 N terminal like Ge1_WD40 PF16529.5 GAM42794.1 - 0.03 13.3 0.1 3.2 6.6 0.0 3.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein His_Phos_2 PF00328.22 GAM42795.1 - 1.1e-13 51.3 0.2 4.6e-12 46.0 0.2 2.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Tricho_coat PF05892.11 GAM42795.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Trichovirus coat protein 2OG-FeII_Oxy_3 PF13640.6 GAM42796.1 - 1.7e-11 44.8 0.1 3e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3201 PF11447.8 GAM42796.1 - 0.0037 16.8 0.1 0.0071 15.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3201) DUF3328 PF11807.8 GAM42797.1 - 1.2e-05 25.2 0.0 1.5e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 GAM42798.1 - 0.044 13.5 3.6 0.13 12.1 3.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) DUF3328 PF11807.8 GAM42799.1 - 2.7e-21 76.3 6.7 1.6e-20 73.9 6.7 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Vpu PF00558.19 GAM42799.1 - 0.0074 16.0 0.4 0.0074 16.0 0.4 1.7 2 0 0 2 2 2 1 Vpu protein Abhydrolase_3 PF07859.13 GAM42800.1 - 1.3e-48 165.6 0.2 2.3e-48 164.9 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAM42800.1 - 7.8e-13 48.1 0.1 2.5e-12 46.4 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family NinF PF05810.12 GAM42800.1 - 0.014 15.2 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 NinF protein DUF2974 PF11187.8 GAM42800.1 - 0.018 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF4147 PF13660.6 GAM42800.1 - 0.035 13.6 0.1 0.054 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) DLH PF01738.18 GAM42800.1 - 0.055 13.0 0.0 4.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Say1_Mug180 PF10340.9 GAM42800.1 - 0.096 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase F-box PF00646.33 GAM42801.1 - 0.6 10.0 2.6 0.84 9.6 0.4 2.4 3 0 0 3 3 3 0 F-box domain Gtr1_RagA PF04670.12 GAM42802.1 - 2.3e-68 230.0 0.1 3e-68 229.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 GAM42802.1 - 5.9e-05 22.6 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAM42802.1 - 0.013 14.9 0.1 0.039 13.4 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAM42802.1 - 0.049 13.7 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM42802.1 - 0.059 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Roc PF08477.13 GAM42802.1 - 0.094 12.9 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 GAM42802.1 - 0.14 12.5 0.0 0.38 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Cyt-b5 PF00173.28 GAM42803.1 - 6.2e-07 29.5 0.0 1.2e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain U1snRNP70_N PF12220.8 GAM42803.1 - 1.1 10.0 8.9 1.9 9.2 0.1 2.5 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ketoacyl-synt PF00109.26 GAM42804.1 - 9.3e-56 189.2 0.0 1.4e-41 142.8 0.0 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAM42804.1 - 1.5e-49 169.2 0.2 3e-49 168.2 0.2 1.5 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 GAM42804.1 - 7e-43 147.1 2.5 2.1e-27 96.4 0.4 4.4 3 2 1 4 4 4 3 Starter unit:ACP transacylase in aflatoxin biosynthesis Ribosomal_S25 PF03297.15 GAM42804.1 - 6.4e-37 125.8 4.4 1.8e-36 124.4 4.4 1.8 1 0 0 1 1 1 1 S25 ribosomal protein Ketoacyl-synt_C PF02801.22 GAM42804.1 - 2.2e-36 124.4 1.0 5.8e-36 123.1 1.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 GAM42804.1 - 4.8e-21 75.9 0.0 1.4e-20 74.4 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain PS-DH PF14765.6 GAM42804.1 - 7.5e-13 48.4 0.0 1.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 GAM42804.1 - 7.3e-12 45.5 0.5 2.5e-11 43.7 0.5 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 GAM42804.1 - 2.6e-07 31.1 0.1 9.6e-07 29.3 0.1 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension HTH_DeoR PF08220.12 GAM42804.1 - 0.076 12.8 0.8 0.73 9.6 0.1 2.9 3 0 0 3 3 3 0 DeoR-like helix-turn-helix domain HTH_24 PF13412.6 GAM42804.1 - 0.099 12.2 0.6 4.5 6.9 0.0 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding ABC_membrane PF00664.23 GAM42805.1 - 2.2e-89 299.8 21.0 3.2e-45 154.9 7.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM42805.1 - 1.2e-71 239.6 0.7 1.4e-36 126.0 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAM42805.1 - 7.3e-12 45.2 8.3 0.0008 18.9 1.6 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAM42805.1 - 7.8e-09 36.1 0.9 0.00079 19.8 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 GAM42805.1 - 8e-09 35.1 0.4 0.0052 16.5 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM42805.1 - 2.7e-08 33.9 0.7 0.0035 17.3 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 GAM42805.1 - 1.4e-07 31.8 0.9 0.011 16.0 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GAM42805.1 - 3.9e-07 30.0 1.9 0.023 14.4 0.2 3.6 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 GAM42805.1 - 6e-07 28.6 1.4 0.01 14.7 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 GAM42805.1 - 1.1e-06 28.6 0.0 0.044 13.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain G-alpha PF00503.20 GAM42805.1 - 2.9e-06 26.7 0.1 0.022 13.9 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Zeta_toxin PF06414.12 GAM42805.1 - 9.8e-06 25.0 1.3 0.0042 16.4 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin MMR_HSR1 PF01926.23 GAM42805.1 - 1.6e-05 24.9 0.0 0.055 13.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 GAM42805.1 - 4.5e-05 23.7 1.0 0.037 14.1 0.0 2.7 2 1 0 2 2 2 1 Helicase HerA, central domain AAA PF00004.29 GAM42805.1 - 6.5e-05 23.4 0.3 1 9.8 0.0 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 GAM42805.1 - 9e-05 22.4 1.8 0.54 10.0 0.0 3.2 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system APS_kinase PF01583.20 GAM42805.1 - 9.2e-05 22.4 0.1 0.045 13.7 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 GAM42805.1 - 0.00021 21.5 0.3 0.52 10.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 GAM42805.1 - 0.00021 21.1 0.0 0.54 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAM42805.1 - 0.00027 20.5 0.0 0.51 9.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 GAM42805.1 - 0.00042 19.7 0.1 0.55 9.5 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family SbcCD_C PF13558.6 GAM42805.1 - 0.00062 20.0 3.5 1.2 9.5 0.4 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 GAM42805.1 - 0.0013 19.3 0.0 2.9 8.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 GAM42805.1 - 0.0017 18.3 0.4 1.7 8.6 0.0 4.0 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 GAM42805.1 - 0.0018 18.8 0.3 2.1 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAM42805.1 - 0.0021 17.3 0.0 0.35 10.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 GAM42805.1 - 0.0022 17.6 0.0 1.1 8.8 0.0 3.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAM42805.1 - 0.0037 16.7 0.1 1.1 8.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IIGP PF05049.13 GAM42805.1 - 0.0044 16.1 0.4 0.19 10.8 0.1 2.3 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) MeaB PF03308.16 GAM42805.1 - 0.0058 15.7 0.0 0.92 8.4 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TniB PF05621.11 GAM42805.1 - 0.012 15.0 0.5 41 3.5 0.0 4.5 5 0 0 5 5 5 0 Bacterial TniB protein PRK PF00485.18 GAM42805.1 - 0.014 15.2 0.2 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 GAM42805.1 - 0.019 15.2 0.1 3.1 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 GAM42805.1 - 0.019 14.3 0.0 0.59 9.4 0.0 2.3 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.23 GAM42805.1 - 0.021 14.9 1.4 1 9.4 0.1 2.6 2 0 0 2 2 2 0 Dynamin family Pox_A32 PF04665.12 GAM42805.1 - 0.032 13.7 0.2 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 GAM42805.1 - 0.033 14.0 0.1 9 6.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 GAM42805.1 - 0.046 12.9 0.0 11 5.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 GAM42805.1 - 0.05 14.0 0.1 9.2 6.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 GAM42805.1 - 0.076 12.9 0.0 5.6 6.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 GAM42805.1 - 0.079 12.9 0.1 15 5.4 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 KAP_NTPase PF07693.14 GAM42805.1 - 0.083 12.1 0.0 3.9 6.6 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain FeoB_N PF02421.18 GAM42805.1 - 0.11 12.0 0.0 5.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 GAM42805.1 - 0.12 12.6 0.0 30 4.8 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 GAM42805.1 - 0.35 10.8 1.9 25 4.7 0.0 3.5 4 0 0 4 4 3 0 NTPase UDPGT PF00201.18 GAM42806.1 - 1.8e-24 86.4 0.0 4.5e-24 85.1 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GAM42806.1 - 2.5e-09 37.3 0.0 4.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 GAM42806.1 - 0.019 15.4 0.0 0.031 14.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_1_3 PF13528.6 GAM42806.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 RTA1 PF04479.13 GAM42807.1 - 6.7e-60 202.2 11.8 6.7e-60 202.2 11.8 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF996 PF06195.13 GAM42807.1 - 0.0026 18.0 4.6 0.0026 18.0 4.6 3.2 1 1 2 4 4 4 3 Protein of unknown function (DUF996) COX7B PF05392.11 GAM42807.1 - 0.85 9.3 4.1 1.9 8.2 0.0 3.2 3 1 1 4 4 4 0 Cytochrome C oxidase chain VIIB ketoacyl-synt PF00109.26 GAM42808.1 - 7.2e-77 258.4 0.2 1.2e-76 257.7 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAM42808.1 - 3.2e-61 206.4 0.5 3.2e-61 206.4 0.5 2.2 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 GAM42808.1 - 1.5e-50 172.1 0.0 4.1e-50 170.7 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAM42808.1 - 1.1e-49 169.7 0.5 4.2e-49 167.8 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM42808.1 - 4e-34 117.1 0.2 1.1e-33 115.7 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAM42808.1 - 1.9e-20 73.4 0.1 7.4e-20 71.5 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 GAM42808.1 - 1.2e-17 64.1 0.0 5.1e-17 62.1 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 GAM42808.1 - 1.3e-15 57.4 5.1 8.5e-15 54.7 0.2 2.7 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 GAM42808.1 - 3.4e-15 57.3 0.0 1.7e-14 55.0 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 GAM42808.1 - 3.1e-07 30.2 1.5 6.9e-07 29.1 0.1 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 GAM42808.1 - 4e-07 30.3 0.0 9.9e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 GAM42808.1 - 1.2e-06 28.4 0.5 3.8e-06 26.8 0.5 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 GAM42808.1 - 7.4e-05 22.2 0.1 0.00016 21.1 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ELFV_dehydrog PF00208.21 GAM42808.1 - 0.03 14.1 2.1 4.9 6.8 0.1 2.6 3 0 0 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.21 GAM42808.1 - 0.065 12.6 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 ThiF family PALP PF00291.25 GAM42808.1 - 6.2 6.1 7.5 0.75 9.1 0.3 2.7 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme Dus PF01207.17 GAM42809.1 - 1.7e-59 201.4 0.0 7.8e-59 199.3 0.0 2.0 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DUF1484 PF07363.11 GAM42809.1 - 0.0072 17.3 3.1 0.66 11.0 1.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1484) BKACE PF05853.12 GAM42809.1 - 0.043 13.1 0.1 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 beta-keto acid cleavage enzyme DHO_dh PF01180.21 GAM42809.1 - 0.098 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Imm39 PF15568.6 GAM42809.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 39 LysM PF01476.20 GAM42810.1 - 2.8e-09 36.9 0.0 1.8e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 LysM domain adh_short PF00106.25 GAM42811.1 - 1.7e-13 50.5 0.0 1.1e-08 34.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42811.1 - 1.6e-07 31.2 0.0 2.8e-06 27.1 0.0 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM42811.1 - 7.2e-05 22.8 0.0 9.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 KR domain STAT_int PF02865.17 GAM42811.1 - 0.0085 16.6 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 STAT protein, protein interaction domain Aldo_ket_red PF00248.21 GAM42812.1 - 2.8e-55 187.6 0.0 3.4e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Inositol_P PF00459.25 GAM42813.1 - 2.6e-73 246.9 0.0 3.3e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family SPT2 PF08243.11 GAM42814.1 - 0.09 13.3 2.2 0.097 13.2 1.7 1.3 1 1 0 1 1 1 0 SPT2 chromatin protein Pox_E6 PF04656.12 GAM42815.1 - 0.00038 19.0 0.0 0.00052 18.6 0.0 1.1 1 0 0 1 1 1 1 Pox virus E6 protein FYRC PF05965.14 GAM42815.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 F/Y rich C-terminus Transferase PF02458.15 GAM42816.1 - 1.3e-19 70.2 0.0 2.2e-17 62.9 0.0 2.0 2 0 0 2 2 2 2 Transferase family SPECT1 PF18680.1 GAM42816.1 - 0.05 13.3 0.1 0.084 12.5 0.1 1.2 1 0 0 1 1 1 0 Plasmodium host cell traversal SPECT1 DUF1365 PF07103.11 GAM42817.1 - 4.5e-22 78.9 0.3 7.8e-22 78.1 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1365) DUF2357 PF09823.9 GAM42817.1 - 0.077 12.2 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) DUF1479 PF07350.12 GAM42818.1 - 2.6e-149 497.5 0.0 3e-149 497.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 GAM42818.1 - 0.013 15.7 0.4 0.62 10.3 0.3 2.7 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Caudo_TAP PF02413.17 GAM42818.1 - 0.11 12.7 0.1 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK DSBA PF01323.20 GAM42819.1 - 1.7e-21 76.9 0.0 2.1e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Hexokinase_2 PF03727.16 GAM42820.1 - 8.9e-64 215.2 0.0 2.3e-62 210.6 0.0 2.1 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 GAM42820.1 - 4.4e-60 203.0 0.0 7.8e-60 202.2 0.0 1.4 1 0 0 1 1 1 1 Hexokinase HemX PF04375.14 GAM42820.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Zn_clus PF00172.18 GAM42821.1 - 6e-07 29.5 9.3 1e-06 28.8 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glucosamine_iso PF01182.20 GAM42822.1 - 9.5e-21 74.7 0.0 1.5e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.13 GAM42822.1 - 0.044 12.9 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain AA_permease_2 PF13520.6 GAM42824.1 - 8.7e-60 202.7 55.8 1.1e-59 202.4 55.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM42824.1 - 5.8e-23 81.2 45.7 7.6e-23 80.8 45.7 1.0 1 0 0 1 1 1 1 Amino acid permease ATPase_gene1 PF09527.10 GAM42826.1 - 0.074 13.2 1.2 0.074 13.2 1.2 1.7 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF1689 PF07954.11 GAM42826.1 - 0.08 13.3 0.0 0.2 12.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1689) DUF883 PF05957.13 GAM42826.1 - 0.3 11.7 5.1 0.51 11.0 0.5 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) LCM PF04072.14 GAM42827.1 - 1.3e-21 77.4 0.0 4.2e-21 75.7 0.0 1.9 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase C1_1 PF00130.22 GAM42827.1 - 0.22 11.5 0.6 0.41 10.6 0.6 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DEAD_2 PF06733.15 GAM42828.1 - 1e-49 168.6 0.9 3e-49 167.0 0.2 2.0 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 GAM42828.1 - 4.2e-45 153.8 3.3 5.7e-41 140.3 1.1 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 GAM42828.1 - 4e-43 147.5 0.0 8.4e-43 146.5 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DUF4953 PF16313.5 GAM42828.1 - 0.19 10.9 0.4 0.53 9.4 0.0 1.8 2 0 0 2 2 2 0 Met-zincin RNA_pol_Rpb1_5 PF04998.17 GAM42829.1 - 2.4e-79 266.5 0.4 4.1e-79 265.8 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAM42829.1 - 4.6e-63 212.4 0.1 9.2e-63 211.4 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 GAM42829.1 - 3.1e-36 124.7 0.0 1.6e-35 122.3 0.0 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 GAM42829.1 - 5.5e-29 101.5 0.0 2.6e-27 96.0 0.0 2.9 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 GAM42829.1 - 5.8e-15 55.2 0.0 5.8e-15 55.2 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Nop14 PF04147.12 GAM42829.1 - 0.019 13.2 22.5 0.032 12.5 22.5 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GAM42829.1 - 3 7.2 32.7 5.7 6.3 32.7 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GAM42829.1 - 4.7 6.4 27.5 8.6 5.6 27.5 1.3 1 0 0 1 1 1 0 BUD22 PRP3 PF08572.10 GAM42830.1 - 1.1e-71 241.1 6.6 2e-71 240.3 6.6 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 GAM42830.1 - 1.2e-47 161.7 0.1 1.2e-47 161.7 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) ASFV_J13L PF05568.11 GAM42830.1 - 5.5 6.7 6.9 5.7 6.6 5.6 1.6 1 1 0 1 1 1 0 African swine fever virus J13L protein Gar1 PF04410.14 GAM42831.1 - 8e-48 162.1 0.4 1.8e-47 161.0 0.4 1.6 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region SR-25 PF10500.9 GAM42831.1 - 2.8 7.5 8.3 10 5.6 1.6 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Glyco_transf_22 PF03901.17 GAM42832.1 - 2.5e-83 280.7 13.8 2.9e-83 280.4 13.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Chitin_synth_1 PF01644.17 GAM42833.1 - 6.9e-69 231.0 0.0 9.9e-69 230.5 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 GAM42833.1 - 1.2e-27 95.6 0.1 3.5e-27 94.1 0.1 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAM42833.1 - 1.1e-23 83.6 0.0 1.2e-19 70.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAM42833.1 - 1.5e-08 34.8 10.8 1.5e-07 31.5 10.8 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAM42833.1 - 1.6e-06 28.2 0.0 4.8e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 2-Hacid_dh_C PF02826.19 GAM42834.1 - 4e-42 143.6 0.1 8.4e-42 142.5 0.1 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAM42834.1 - 2.6e-24 85.4 0.0 7.7e-24 83.9 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 GAM42834.1 - 2.7e-06 27.5 0.0 4.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.17 GAM42834.1 - 1.1e-05 26.0 0.5 9.8e-05 22.9 0.1 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.6 GAM42834.1 - 3.5e-05 24.3 0.2 0.0028 18.2 0.1 2.2 2 0 0 2 2 2 1 XdhC Rossmann domain IlvN PF07991.12 GAM42834.1 - 0.0021 17.6 0.1 0.0042 16.7 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 GAM42834.1 - 0.021 14.2 2.9 0.073 12.4 2.8 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 GAM42834.1 - 0.024 14.9 2.0 0.67 10.2 0.2 2.7 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 GAM42834.1 - 0.064 13.4 0.4 0.14 12.3 0.4 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MAP65_ASE1 PF03999.12 GAM42835.1 - 1.1 7.9 2.3 1.3 7.7 2.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Rav1p_C PF12234.8 GAM42836.1 - 3e-283 941.1 0.0 5.2e-283 940.3 0.0 1.4 1 0 0 1 1 1 1 RAVE protein 1 C terminal Sfi1 PF08457.10 GAM42836.1 - 1e-177 592.2 78.8 1e-177 592.2 78.8 2.2 1 1 1 2 2 2 2 Sfi1 spindle body protein ANAPC4_WD40 PF12894.7 GAM42836.1 - 0.0029 17.9 0.2 30 5.0 0.1 4.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain tRNA-synt_1 PF00133.22 GAM42837.1 - 7.8e-221 734.5 0.0 1.1e-220 733.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAM42837.1 - 4e-26 91.8 0.0 1e-25 90.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAM42837.1 - 1.9e-12 46.7 0.0 0.00018 20.4 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 GAM42837.1 - 0.066 12.5 0.1 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Uso1_p115_head PF04869.14 GAM42838.1 - 4.1e-109 364.5 0.0 8.7e-109 363.4 0.0 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 GAM42838.1 - 5.9e-13 49.3 70.4 1.5e-05 25.4 70.4 3.8 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region PKK PF12474.8 GAM42838.1 - 0.00023 21.3 27.0 0.00023 21.3 27.0 4.0 1 1 1 4 4 4 2 Polo kinase kinase DUF3584 PF12128.8 GAM42838.1 - 1.3 6.5 57.9 1.9 5.9 57.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) XRN_M PF17846.1 GAM42839.1 - 3.2e-144 481.2 2.5 3.4e-143 477.8 0.0 2.5 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 GAM42839.1 - 7.1e-101 336.7 1.7 5.7e-100 333.7 0.0 2.1 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 GAM42839.1 - 0.0019 18.2 1.8 0.0035 17.4 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle UDPG_MGDP_dh_N PF03721.14 GAM42839.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-CCHC_2 PF13696.6 GAM42839.1 - 0.16 11.8 1.6 0.32 10.8 1.6 1.5 1 0 0 1 1 1 0 Zinc knuckle EPSP_synthase PF00275.20 GAM42840.1 - 3.6e-123 411.4 0.0 5.2e-123 410.8 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 GAM42840.1 - 1.2e-100 336.1 0.1 1.9e-100 335.4 0.1 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 GAM42840.1 - 1.5e-57 195.5 0.0 2.9e-57 194.6 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 GAM42840.1 - 2e-38 132.0 0.0 2.2e-36 125.4 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 GAM42840.1 - 4.7e-24 84.5 0.0 1.4e-23 83.0 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 GAM42840.1 - 7.8e-09 35.2 0.3 2.9e-08 33.4 0.1 2.1 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 GAM42840.1 - 3.8e-08 33.3 0.1 1e-07 31.9 0.1 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_16 PF13191.6 GAM42840.1 - 0.0013 19.1 0.4 2.3 8.6 0.0 3.8 4 0 0 4 4 4 1 AAA ATPase domain AAA_18 PF13238.6 GAM42840.1 - 0.022 15.3 0.0 0.071 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAM42840.1 - 0.053 13.8 0.0 0.32 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAM42840.1 - 0.064 13.0 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 GAM42840.1 - 0.14 12.1 0.0 0.44 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.26 GAM42841.1 - 7.5e-10 38.7 15.0 0.00016 22.0 1.4 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM42841.1 - 5.4e-06 26.8 10.8 0.029 15.2 1.1 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAM42841.1 - 0.11 12.9 5.4 19 5.9 1.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.15 GAM42841.1 - 0.35 10.9 2.0 0.88 9.6 2.0 1.7 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.12 GAM42841.1 - 0.56 10.5 6.5 0.94 9.8 1.5 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CENP-T_C PF15511.6 GAM42842.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 GAM42842.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 GAM42842.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 GAM42842.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 GAM42842.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 GAM42842.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAM42842.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 GAM42842.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 GAM42842.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 GAM42843.1 - 1e-51 174.7 2.5 1.1e-51 174.6 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GAM42843.1 - 6e-06 26.6 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 GAM42843.1 - 4.9e-05 23.4 0.5 7.4e-05 22.8 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 GAM42843.1 - 6.5e-05 23.5 1.2 7.7e-05 23.3 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 GAM42843.1 - 0.0032 17.7 0.3 0.0065 16.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAM42843.1 - 0.026 14.6 0.2 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit MFS_1 PF07690.16 GAM42844.1 - 6.7e-40 137.1 49.8 2.9e-39 135.0 46.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM42844.1 - 3e-10 39.5 8.9 3e-10 39.5 8.9 3.5 2 1 2 4 4 4 1 Sugar (and other) transporter Anophelin PF10731.9 GAM42844.1 - 0.31 10.9 1.1 0.87 9.5 1.1 1.7 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Mpv17_PMP22 PF04117.12 GAM42845.1 - 4.4e-16 58.9 0.2 4.4e-16 58.9 0.2 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family Exo5 PF09810.9 GAM42846.1 - 1.7e-140 468.7 0.0 3.5e-140 467.7 0.0 1.5 2 0 0 2 2 2 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 GAM42846.1 - 0.00052 20.0 0.2 0.88 9.4 0.0 3.4 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily DUF3799 PF12684.7 GAM42846.1 - 0.0033 17.2 0.0 0.0082 15.9 0.0 1.6 2 0 0 2 2 2 1 PDDEXK-like domain of unknown function (DUF3799) DUF3445 PF11927.8 GAM42847.1 - 4.3e-81 271.8 0.0 5.9e-81 271.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF4079 PF13301.6 GAM42847.1 - 0.085 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) Baculo_11_kDa PF06143.11 GAM42847.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family NmrA PF05368.13 GAM42848.1 - 3.8e-36 124.8 0.0 9.4e-36 123.5 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM42848.1 - 9.6e-09 35.4 0.3 1.4e-08 34.8 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 GAM42848.1 - 9.8e-05 22.6 0.1 0.00017 21.8 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 GAM42848.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 GAM42848.1 - 0.0077 16.8 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 GAM42848.1 - 0.012 15.9 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 GAM42848.1 - 0.016 14.7 0.1 0.049 13.1 0.1 1.9 2 0 0 2 2 2 0 short chain dehydrogenase PALP PF00291.25 GAM42848.1 - 0.067 12.6 0.1 0.097 12.1 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme KR PF08659.10 GAM42848.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 KR domain DUF3425 PF11905.8 GAM42849.1 - 2.5e-18 66.2 0.1 3.4e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) OPT PF03169.15 GAM42850.1 - 3.6e-160 534.6 19.1 4.3e-160 534.3 19.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SH3_9 PF14604.6 GAM42851.1 - 1.7e-07 31.0 0.0 2.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM42851.1 - 3.2e-05 23.4 0.0 4.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAM42851.1 - 4.9e-05 22.9 0.0 8.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain GT87 PF09594.10 GAM42851.1 - 0.2 11.3 5.5 0.73 9.5 0.3 2.8 3 0 0 3 3 3 0 Glycosyltransferase family 87 Apt1 PF10351.9 GAM42851.1 - 0.66 8.8 6.8 0.89 8.3 6.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Red1 PF07964.11 GAM42851.1 - 1.1 7.4 9.5 1.5 6.9 9.5 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Pkinase PF00069.25 GAM42852.1 - 5.2e-43 147.3 0.0 7.8e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM42852.1 - 1.4e-16 60.6 0.0 2.1e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM42852.1 - 0.012 15.6 0.2 0.089 12.7 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 GAM42852.1 - 0.018 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like KIX_2 PF16987.5 GAM42852.1 - 0.022 14.7 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 KIX domain Pkinase_fungal PF17667.1 GAM42852.1 - 0.045 12.5 0.0 0.075 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase muHD PF10291.9 GAM42853.1 - 1.4e-85 287.0 0.4 1.9e-85 286.5 0.4 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 GAM42853.1 - 2.4e-06 27.8 0.0 1.5e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BAR PF03114.18 GAM42853.1 - 0.053 13.2 0.7 0.1 12.2 0.7 1.4 1 0 0 1 1 1 0 BAR domain MAD PF05557.13 GAM42854.1 - 1.6e-48 165.6 77.7 2.4e-38 132.0 78.5 3.3 2 1 0 2 2 2 2 Mitotic checkpoint protein Bacillus_HBL PF05791.11 GAM42854.1 - 0.013 15.3 10.8 0.013 15.3 10.8 5.5 5 2 1 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) HALZ PF02183.18 GAM42854.1 - 0.6 10.4 28.1 7.6 6.8 0.5 7.8 6 0 0 6 6 6 0 Homeobox associated leucine zipper DUF1474 PF07342.11 GAM42854.1 - 0.94 10.0 4.3 0.57 10.7 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1474) DUF1664 PF07889.12 GAM42854.1 - 2 8.5 35.8 0.72 9.9 8.3 5.5 5 1 1 6 6 6 0 Protein of unknown function (DUF1664) Ribosomal_L7Ae PF01248.26 GAM42855.1 - 4e-19 68.2 1.0 4e-19 68.2 1.0 2.5 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MSC PF09402.10 GAM42855.1 - 0.02 14.4 1.2 0.032 13.7 1.2 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Urocanase PF01175.18 GAM42855.1 - 0.13 11.9 0.9 0.18 11.4 0.9 1.1 1 0 0 1 1 1 0 Urocanase Rossmann-like domain Ribosomal_L7Ae PF01248.26 GAM42856.1 - 1.6e-24 85.4 0.0 1.8e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family E7 PF00527.18 GAM42857.1 - 0.042 14.0 1.6 9 6.6 0.0 3.0 3 0 0 3 3 3 0 E7 protein, Early protein MMR_HSR1_C PF08438.10 GAM42860.1 - 1.1e-35 122.6 0.0 2.3e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 GAM42860.1 - 6.7e-18 64.8 0.0 1.9e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM42860.1 - 5.4e-07 29.3 0.0 5.4e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 GAM42860.1 - 0.034 14.2 0.2 0.067 13.2 0.2 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GTP_EFTU PF00009.27 GAM42860.1 - 0.11 12.0 1.4 0.55 9.7 0.0 2.4 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain SET PF00856.28 GAM42862.1 - 0.00041 20.8 0.0 0.0034 17.8 0.0 2.1 2 0 0 2 2 2 1 SET domain DUF4145 PF13643.6 GAM42862.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) Fungal_trans PF04082.18 GAM42863.1 - 4.7e-30 104.5 0.0 7.8e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM42863.1 - 7.9e-08 32.3 16.0 1.3e-07 31.6 16.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 GAM42863.1 - 0.11 12.7 0.0 0.11 12.7 0.0 2.4 3 0 0 3 3 3 0 bZIP transcription factor Hydrolase_4 PF12146.8 GAM42864.1 - 2e-12 46.9 0.0 1.5e-09 37.5 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM42864.1 - 6.7e-09 36.7 0.3 1.2e-08 35.8 0.1 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.11 GAM42864.1 - 2.6e-08 33.1 0.0 3.6e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 GAM42864.1 - 1.1e-05 25.2 0.1 0.00012 21.8 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM42864.1 - 2.2e-05 24.0 0.0 5.6e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GAM42864.1 - 0.00013 21.6 0.2 0.0023 17.6 0.0 2.4 1 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 GAM42864.1 - 0.0017 18.0 0.0 0.016 14.7 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 GAM42864.1 - 0.013 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 GAM42864.1 - 0.016 13.9 0.0 0.028 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.20 GAM42864.1 - 0.019 14.6 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Asp2 PF16929.5 GAM42864.1 - 0.035 13.1 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter UPF0227 PF05728.12 GAM42864.1 - 0.037 14.0 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) FSH1 PF03959.13 GAM42864.1 - 0.038 13.6 0.0 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Fungal_trans PF04082.18 GAM42865.1 - 8.6e-11 41.4 0.0 1.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM42865.1 - 4.1e-06 26.8 11.8 4.1e-06 26.8 11.8 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM42866.1 - 3.2e-18 65.7 0.1 5.5e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM42866.1 - 7.6e-11 42.0 11.5 1.4e-10 41.1 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transketolase_N PF00456.21 GAM42867.1 - 8.2e-152 505.0 0.1 1.1e-151 504.5 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAM42867.1 - 1.3e-44 152.0 0.0 2.3e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAM42867.1 - 7.8e-12 45.2 0.0 2.1e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAM42867.1 - 3.9e-05 23.0 0.1 0.00041 19.7 0.1 2.0 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 GAM42867.1 - 0.01 14.8 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component ThiP_synth PF10120.9 GAM42867.1 - 0.08 12.6 0.1 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Thiamine-phosphate synthase Beta_elim_lyase PF01212.21 GAM42867.1 - 0.086 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Alba PF01918.21 GAM42867.1 - 0.27 11.1 0.8 1 9.2 0.1 2.2 2 0 0 2 2 2 0 Alba Spermine_synth PF01564.17 GAM42868.1 - 6.2e-74 247.5 0.0 8.4e-74 247.1 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 GAM42868.1 - 1.9e-23 82.1 0.1 3.2e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 GAM42868.1 - 0.00023 21.8 0.0 0.00048 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM42868.1 - 0.006 17.3 0.0 0.017 15.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 GAM42868.1 - 0.02 14.1 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_18 PF12847.7 GAM42868.1 - 0.035 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 GAM42868.1 - 0.16 11.3 0.1 0.39 10.0 0.1 1.6 1 1 1 2 2 2 0 O-methyltransferase domain UcrQ PF02939.16 GAM42869.1 - 9.3e-34 115.2 0.3 1.1e-33 115.0 0.3 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 GAM42869.1 - 0.022 15.2 0.0 0.029 14.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Band_7 PF01145.25 GAM42870.1 - 3.4e-24 85.8 6.5 6.2e-24 85.0 5.9 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 GAM42870.1 - 0.0015 17.6 3.7 0.002 17.2 3.7 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial PknG_rubred PF16919.5 GAM42870.1 - 0.096 12.9 0.2 0.16 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain Methyltransf_34 PF11312.8 GAM42871.1 - 2.4e-105 352.2 0.1 3.5e-105 351.6 0.1 1.2 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Abhydrolase_3 PF07859.13 GAM42873.1 - 4.2e-37 128.1 0.0 5.1e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM42873.1 - 1.9e-05 24.2 0.0 3.6e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAM42873.1 - 7.6e-05 23.4 0.0 0.00011 22.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAM42873.1 - 0.00025 20.7 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.12 GAM42873.1 - 0.0013 17.4 0.0 0.22 10.1 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 GAM42873.1 - 0.0048 16.7 0.0 0.0082 16.0 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2974 PF11187.8 GAM42873.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Aldo_ket_red PF00248.21 GAM42874.1 - 2.1e-50 171.6 0.0 2.4e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tubulin PF00091.25 GAM42876.1 - 1.3e-59 201.8 0.0 2.3e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAM42876.1 - 1.4e-44 151.3 0.3 1.4e-44 151.3 0.3 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAM42876.1 - 0.031 13.9 0.0 0.082 12.6 0.0 1.7 1 0 0 1 1 1 0 Tubulin domain DUF202 PF02656.15 GAM42877.1 - 4e-22 78.4 0.4 4e-22 78.4 0.4 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF202) PTPA PF03095.15 GAM42878.1 - 8.3e-109 363.7 0.0 9.9e-109 363.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein NLRC4_HD2 PF17776.1 GAM42878.1 - 0.03 14.9 0.0 4.5 7.8 0.0 3.1 3 0 0 3 3 3 0 NLRC4 helical domain HD2 zf-AN1 PF01428.16 GAM42879.1 - 9.6e-13 48.1 6.0 9.6e-13 48.1 6.0 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 GAM42879.1 - 0.032 14.6 5.3 0.032 14.6 5.3 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DUF1754 PF08555.10 GAM42880.1 - 4.8e-14 52.9 22.0 7e-14 52.4 22.0 1.2 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CDC27 PF09507.10 GAM42880.1 - 0.01 15.3 16.8 0.011 15.1 16.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Trypan_PARP PF05887.11 GAM42880.1 - 0.37 10.8 6.9 0.56 10.2 6.9 1.4 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) hDGE_amylase PF14701.6 GAM42880.1 - 0.53 9.3 4.1 0.62 9.1 4.1 1.0 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF3987 PF13148.6 GAM42880.1 - 1.8 7.5 6.5 1 8.3 4.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3987) Adaptin_binding PF10199.9 GAM42880.1 - 4.3 8.0 15.0 9 6.9 15.0 1.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 FYVE_2 PF02318.16 GAM42880.1 - 7.9 6.7 8.1 1.4 9.2 4.1 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger EamA PF00892.20 GAM42881.1 - 3.8e-13 49.8 24.5 2.3e-06 27.8 0.6 2.4 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 GAM42881.1 - 0.00016 21.3 2.0 0.00016 21.3 2.0 1.8 2 0 0 2 2 2 1 Solute carrier family 35 CSG2 PF16965.5 GAM42881.1 - 0.00018 20.6 13.8 0.00063 18.8 10.1 2.5 2 1 0 2 2 2 1 Ceramide synthase regulator Nuc_sug_transp PF04142.15 GAM42881.1 - 0.016 14.4 6.7 0.05 12.8 6.7 1.7 1 1 0 1 1 1 0 Nucleotide-sugar transporter UAA PF08449.11 GAM42881.1 - 0.033 13.4 3.3 0.051 12.8 3.3 1.4 1 0 0 1 1 1 0 UAA transporter family DUF4395 PF14340.6 GAM42881.1 - 6.3 7.1 12.3 0.88 9.9 0.8 4.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4395) DUF202 PF02656.15 GAM42881.1 - 7.2 7.1 21.4 2.1 8.9 6.7 4.7 4 2 0 4 4 4 0 Domain of unknown function (DUF202) Actin PF00022.19 GAM42882.1 - 3.2e-108 362.0 0.0 2.1e-107 359.3 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 GAM42882.1 - 7.9e-05 21.6 0.0 0.00026 19.9 0.0 1.7 1 1 0 1 1 1 1 MreB/Mbl protein Actin_micro PF17003.5 GAM42882.1 - 0.18 11.0 0.3 2.1 7.4 0.2 2.1 2 0 0 2 2 2 0 Putative actin-like family NAD_binding_2 PF03446.15 GAM42883.1 - 8.2e-22 78.1 0.0 1.7e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3425 PF11905.8 GAM42883.1 - 2.6e-18 66.2 1.2 5.5e-18 65.1 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) NAD_binding_11 PF14833.6 GAM42883.1 - 2.3e-11 44.0 0.0 4.5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase bZIP_1 PF00170.21 GAM42883.1 - 0.014 15.4 10.7 0.034 14.2 9.8 2.0 1 1 1 2 2 2 0 bZIP transcription factor COG5 PF10392.9 GAM42883.1 - 0.039 14.1 1.3 7.2 6.8 2.7 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 GTP_cyclohydro2 PF00925.20 GAM42884.1 - 2.6e-56 189.7 0.0 3.7e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF1325 PF07039.11 GAM42885.1 - 4.7e-34 117.3 0.0 1.7e-33 115.5 0.0 2.0 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 GAM42885.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain PMI_typeI PF01238.21 GAM42886.1 - 3.5e-147 490.5 0.0 4.1e-147 490.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Coatomer_E PF04733.14 GAM42887.1 - 2.6e-65 220.7 3.5 3e-65 220.5 3.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 GAM42887.1 - 2.8e-11 43.8 15.4 4.4e-05 23.9 3.1 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM42887.1 - 5.3e-08 33.4 11.1 0.0078 16.8 0.2 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM42887.1 - 8.2e-08 32.4 0.5 0.0018 18.4 1.1 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAM42887.1 - 9.6e-06 25.9 3.4 3.4 8.5 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM42887.1 - 1.3e-05 25.4 9.5 0.0032 17.7 1.8 3.8 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM42887.1 - 2.1e-05 25.0 16.2 0.0032 18.2 0.2 4.9 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAM42887.1 - 0.00011 22.5 20.7 0.042 14.5 0.4 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAM42887.1 - 0.00049 19.8 4.2 0.16 11.9 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAM42887.1 - 0.00094 18.5 2.5 0.011 14.9 0.9 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM42887.1 - 0.0016 18.4 15.9 0.0081 16.2 0.1 4.9 6 0 0 6 6 5 1 Tetratricopeptide repeat Type_III_YscG PF09477.10 GAM42887.1 - 0.0087 16.1 1.8 0.11 12.6 1.0 2.8 2 1 1 3 3 3 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_10 PF13374.6 GAM42887.1 - 0.018 14.9 5.7 4.3 7.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAM42887.1 - 0.02 15.2 0.8 3.4 8.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAM42887.1 - 0.04 14.1 4.0 0.26 11.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat HWE_HK PF07536.14 GAM42887.1 - 0.11 13.2 3.5 43 4.9 0.0 3.7 2 1 1 4 4 4 0 HWE histidine kinase Glyco_hydro_16 PF00722.21 GAM42890.1 - 7.2e-40 136.3 3.0 7.2e-40 136.3 3.0 2.0 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 Lip_prot_lig_C PF10437.9 GAM42890.1 - 0.18 11.8 0.2 0.4 10.7 0.2 1.6 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus RAP1 PF07218.11 GAM42890.1 - 2.8 6.1 6.6 3.2 5.9 6.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Stanniocalcin PF03298.13 GAM42891.1 - 4.4e-05 22.9 0.1 4.9e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Stanniocalcin family MID_MedPIWI PF18296.1 GAM42891.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 MID domain of medPIWI Toxin_22 PF08092.11 GAM42891.1 - 2 8.5 6.7 7.1 6.8 6.3 2.1 2 1 0 2 2 2 0 Magi peptide toxin family PI-PLC-X PF00388.19 GAM42892.1 - 1.7e-60 202.8 0.0 2.9e-60 202.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 GAM42892.1 - 3.2e-45 153.2 0.1 4.8e-42 142.9 0.1 2.6 2 0 0 2 2 2 2 Phosphatidylinositol-specific phospholipase C, Y domain GDPD PF03009.17 GAM42892.1 - 0.0062 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_1 PF00036.32 GAM42892.1 - 0.0074 15.8 0.1 0.081 12.5 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_like PF09279.11 GAM42892.1 - 0.034 14.6 0.3 0.077 13.5 0.1 1.7 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.6 GAM42892.1 - 0.2 12.2 0.5 1.6 9.2 0.1 2.5 2 1 1 3 3 3 0 EF-hand domain pair E_Pc_C PF06752.12 GAM42892.1 - 0.27 11.3 11.1 1.1 9.4 11.4 1.9 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus DUF3439 PF11921.8 GAM42892.1 - 2.2 8.3 11.5 5.6 7.0 11.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AAA_12 PF13087.6 GAM42893.1 - 7e-59 198.8 0.0 1.4e-58 197.8 0.0 1.5 2 0 0 2 2 2 1 AAA domain UPF1_Zn_bind PF09416.10 GAM42893.1 - 1.1e-55 187.7 0.1 4.3e-55 185.9 0.0 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.6 GAM42893.1 - 1.6e-54 185.5 2.7 3.4e-31 109.0 0.2 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 GAM42893.1 - 1.6e-33 114.8 0.0 2.9e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 GAM42893.1 - 1.3e-13 51.2 0.3 1.9e-12 47.3 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM42893.1 - 2.7e-11 44.0 0.1 2.4e-10 40.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 GAM42893.1 - 7.7e-06 26.0 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 GAM42893.1 - 3e-05 23.9 0.2 0.3 10.8 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 GAM42893.1 - 0.00057 19.2 0.1 0.012 14.9 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 GAM42893.1 - 0.00058 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 GAM42893.1 - 0.0019 17.8 0.0 0.024 14.1 0.0 2.3 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 GAM42893.1 - 0.0023 17.1 0.1 0.56 9.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase DEAD PF00270.29 GAM42893.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_10 PF12846.7 GAM42893.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ATPase PF06745.13 GAM42893.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 GAM42893.1 - 0.14 12.5 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Brix PF04427.18 GAM42894.1 - 1.3e-30 107.0 0.0 1.6e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Brix domain PTCB-BRCT PF12738.7 GAM42895.1 - 7.9e-09 35.3 0.1 1.9e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 GAM42895.1 - 2.2e-08 34.4 0.1 4.9e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain WGR PF05406.15 GAM42895.1 - 6.2e-06 26.2 0.8 1.9e-05 24.6 0.1 2.1 2 0 0 2 2 2 1 WGR domain BRCT_2 PF16589.5 GAM42895.1 - 5.9e-05 23.4 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 GAM42895.1 - 0.00016 21.9 0.1 0.00053 20.2 0.1 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain Poty_PP PF08440.10 GAM42895.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Potyviridae polyprotein BRCT_3 PF18428.1 GAM42895.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain IGPS PF00218.21 GAM42896.1 - 2.2e-96 321.9 0.0 1.1e-95 319.6 0.0 1.9 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 GAM42896.1 - 8.3e-56 188.9 0.1 5.4e-51 173.1 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 GAM42896.1 - 1.8e-46 158.3 0.0 3e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAM42896.1 - 5.6e-05 23.0 0.2 0.00021 21.1 0.2 1.9 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 GAM42896.1 - 0.0013 18.5 1.4 0.017 14.9 0.1 2.9 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain Peripla_BP_2 PF01497.18 GAM42896.1 - 0.0044 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Periplasmic binding protein NanE PF04131.14 GAM42896.1 - 0.0046 16.2 0.5 0.17 11.1 0.0 2.7 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 GAM42896.1 - 0.014 14.9 0.6 0.3 10.5 0.0 2.6 3 0 0 3 3 3 0 Histidine biosynthesis protein YjeF_N PF03853.15 GAM42896.1 - 0.065 13.1 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 YjeF-related protein N-terminus Nup188_C PF18378.1 GAM42897.1 - 5.1e-144 479.7 0.4 8.1e-144 479.0 0.4 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 GAM42897.1 - 4.5e-76 256.6 0.0 6.9e-75 252.6 0.0 2.3 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Drf_FH3 PF06367.16 GAM42897.1 - 0.19 11.3 0.3 22 4.6 0.0 3.5 4 0 0 4 4 4 0 Diaphanous FH3 Domain DUF4570 PF15134.6 GAM42897.1 - 0.51 10.4 1.8 1.3 9.1 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) G-alpha PF00503.20 GAM42898.1 - 5.8e-122 407.2 1.3 6.7e-122 407.0 1.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM42898.1 - 1.7e-14 53.6 1.6 2e-09 37.2 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 GAM42898.1 - 1.3e-05 24.9 0.0 5.5e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 GAM42898.1 - 0.0013 18.2 2.0 0.072 12.4 0.0 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 GAM42898.1 - 0.0057 16.4 0.1 0.041 13.6 0.1 2.2 1 1 1 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 GAM42898.1 - 0.026 14.8 0.7 2.4 8.4 0.0 2.8 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 GAM42898.1 - 0.072 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 GAM42898.1 - 0.13 11.8 0.1 1.7 8.1 0.1 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 GAM42898.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 GAM42898.1 - 0.16 12.1 0.1 12 6.1 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Use1 PF09753.9 GAM42899.1 - 4.4e-10 39.7 0.6 8.4e-10 38.8 0.6 1.7 1 1 0 1 1 1 1 Membrane fusion protein Use1 Sacchrp_dh_NADP PF03435.18 GAM42900.1 - 8.5e-12 45.5 0.0 1.3e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAM42900.1 - 0.16 12.0 0.0 0.59 10.2 0.0 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 GAM42901.1 - 2e-20 73.1 0.1 3.1e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM42901.1 - 7.3e-19 69.1 0.0 9.3e-18 65.6 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM42901.1 - 1.6e-07 31.2 0.0 6.8e-07 29.1 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 GAM42901.1 - 0.044 14.1 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF1771 PF08590.10 GAM42903.1 - 2.1e-25 88.9 8.5 6.3e-25 87.3 8.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 GAM42903.1 - 2.6e-11 43.7 0.9 9.1e-11 42.0 0.3 2.2 3 0 0 3 3 3 1 Smr domain CsgA PF17334.2 GAM42903.1 - 0.15 12.8 3.6 3.9 8.3 0.8 2.6 3 0 0 3 3 3 0 Minor curli fiber component A Peripla_BP_3 PF13377.6 GAM42903.1 - 0.88 9.9 3.0 0.99 9.7 0.2 2.1 2 0 0 2 2 2 0 Periplasmic binding protein-like domain DUF4407 PF14362.6 GAM42903.1 - 7.6 5.8 6.3 0.71 9.2 1.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) polyprenyl_synt PF00348.17 GAM42904.1 - 1.8e-67 227.1 0.0 2.3e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CDC14 PF08045.11 GAM42905.1 - 1.7e-131 437.5 0.0 1.9e-131 437.4 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component End3 PF12761.7 GAM42906.1 - 3.8e-71 239.4 1.6 5.2e-71 238.9 1.6 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 GAM42906.1 - 6.8e-53 177.0 0.1 2.2e-49 165.7 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 GAM42906.1 - 1.7e-08 33.4 0.3 1.8e-07 30.2 0.3 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 GAM42906.1 - 1.7e-06 28.4 3.0 5.2e-06 26.8 0.1 2.8 3 0 0 3 3 2 1 EF-hand domain pair EF-hand_8 PF13833.6 GAM42906.1 - 2.3e-05 24.1 0.1 0.0049 16.7 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GAM42906.1 - 3.5e-05 23.4 0.6 0.0004 20.1 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 GAM42906.1 - 0.0024 17.3 1.0 0.0095 15.4 0.2 2.3 2 0 0 2 2 2 1 EF hand RPW8 PF05659.11 GAM42906.1 - 0.016 14.9 1.5 0.035 13.8 0.2 2.0 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 NPV_P10 PF05531.12 GAM42906.1 - 0.31 11.5 0.8 1 9.9 0.3 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 GAM42906.1 - 0.32 10.3 6.0 0.79 9.0 6.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 GAM42906.1 - 0.35 9.7 8.7 0.18 10.7 3.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 GAM42906.1 - 0.65 10.1 10.1 0.22 11.6 2.0 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.11 GAM42906.1 - 1.1 9.5 4.3 2 8.7 0.3 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4201 PF13870.6 GAM42906.1 - 1.2 8.9 12.0 0.19 11.5 5.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) SlyX PF04102.12 GAM42906.1 - 1.4 9.6 4.9 19 6.0 0.1 3.1 2 1 0 2 2 2 0 SlyX ADIP PF11559.8 GAM42906.1 - 2.2 8.3 9.9 1.6 8.8 4.2 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding RRP36 PF06102.12 GAM42906.1 - 9 6.2 12.1 0.49 10.4 3.8 2.3 1 1 1 2 2 2 0 rRNA biogenesis protein RRP36 SNF2_N PF00176.23 GAM42907.1 - 7.6e-64 215.6 2.7 8.5e-64 215.5 0.0 2.2 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM42907.1 - 6e-22 78.1 0.3 3.2e-21 75.8 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM42907.1 - 1.4e-06 28.4 0.0 4.5e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAM42907.1 - 6.9e-06 25.4 0.0 9.6e-05 21.7 0.0 2.3 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DSPc PF00782.20 GAM42908.1 - 4.7e-12 45.9 0.0 1.2e-11 44.5 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain zf-C2H2 PF00096.26 GAM42909.1 - 3e-06 27.4 15.1 0.14 12.6 2.4 3.9 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 GAM42909.1 - 3.1e-06 27.5 1.0 3.8e-06 27.2 0.1 1.5 2 0 0 2 2 2 1 Aberrant zinc-finger Cnn_1N PF07989.11 GAM42909.1 - 0.016 15.4 0.9 0.039 14.1 0.5 1.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 zf-C2H2_4 PF13894.6 GAM42909.1 - 0.04 14.8 7.8 19 6.4 0.6 3.9 3 1 0 3 3 3 0 C2H2-type zinc finger Transpos_assoc PF13963.6 GAM42909.1 - 0.078 13.3 3.0 0.12 12.7 0.2 2.2 2 0 0 2 2 2 0 Transposase-associated domain Trimer_CC PF08954.11 GAM42909.1 - 0.11 12.1 2.0 0.25 10.9 2.0 1.5 1 0 0 1 1 1 0 Trimerisation motif zf-H2C2_2 PF13465.6 GAM42909.1 - 0.84 10.2 10.9 7.2 7.2 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Aldo_ket_red PF00248.21 GAM42910.1 - 2.6e-57 194.3 0.0 2.9e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPP_enzyme_N PF02776.18 GAM42911.1 - 1.2e-20 73.9 0.0 2.1e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAM42911.1 - 5.6e-13 48.9 0.1 3.1e-12 46.5 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PEP_mutase PF13714.6 GAM42912.1 - 1.8e-44 152.0 0.2 3e-44 151.3 0.0 1.4 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase TauD PF02668.16 GAM42913.1 - 5.8e-24 85.3 0.1 8.3e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 GAM42914.1 - 2e-15 56.6 35.7 2e-15 56.6 35.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 GAM42914.1 - 0.065 13.0 0.2 0.065 13.0 0.2 3.2 4 1 1 5 5 5 0 Lipopolysaccharide assembly protein A domain Glyco_hydro_31 PF01055.26 GAM42915.1 - 3.2e-124 415.5 3.3 4.4e-124 415.0 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 GAM42915.1 - 1.2e-30 106.1 0.0 2.7e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase GMC_oxred_N PF00732.19 GAM42916.1 - 8.6e-52 176.3 0.0 1.3e-51 175.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM42916.1 - 6e-33 114.4 0.0 1.2e-32 113.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 GAM42916.1 - 5.8e-06 26.1 0.0 0.00067 19.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM42916.1 - 6.1e-05 22.3 0.1 0.0062 15.7 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GAM42916.1 - 0.00097 19.3 0.4 0.005 17.0 0.5 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAM42916.1 - 0.0033 16.4 0.1 0.0049 15.8 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 GAM42916.1 - 0.0035 16.5 0.1 0.0058 15.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAM42916.1 - 0.0074 15.5 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM42916.1 - 0.017 14.4 0.1 3.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GST_N_3 PF13417.6 GAM42917.1 - 6e-08 33.0 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAM42917.1 - 9.4e-06 25.9 0.0 2.3e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM42917.1 - 0.00048 20.4 0.0 0.0014 18.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Homeobox_KN PF05920.11 GAM42917.1 - 0.026 14.4 0.2 3.7 7.5 0.1 2.4 2 0 0 2 2 2 0 Homeobox KN domain A_deaminase PF00962.22 GAM42918.1 - 8.6e-09 35.2 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase RRP7 PF12923.7 GAM42918.1 - 0.059 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RVT_1 PF00078.27 GAM42919.1 - 1.1e-05 25.1 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ThiD2 PF17792.1 GAM42919.1 - 0.036 14.5 0.5 1.9 9.0 0.0 3.4 3 0 0 3 3 3 0 ThiD2 family CENP-B_dimeris PF09026.10 GAM42919.1 - 0.054 13.9 17.2 0.04 14.3 3.2 3.6 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Transp_cyt_pur PF02133.15 GAM42920.1 - 3.1e-152 507.4 45.7 3.6e-152 507.2 45.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Urb2 PF10441.9 GAM42921.1 - 2.3e-22 79.9 0.2 1.2e-21 77.6 0.0 2.4 2 0 0 2 2 2 1 Urb2/Npa2 family DUF543 PF04418.12 GAM42922.1 - 2.6e-28 97.8 0.0 3.1e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) GST_N_4 PF17172.4 GAM42924.1 - 8.5e-22 77.8 0.1 1.9e-21 76.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 GAM42924.1 - 1.8e-18 66.0 0.1 3.6e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 GAM42924.1 - 1.1e-12 48.3 0.2 3.9e-12 46.6 0.1 2.0 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 GAM42924.1 - 2.5e-06 27.8 0.0 5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 GAM42924.1 - 0.0027 17.7 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_31 PF13847.6 GAM42925.1 - 9.6e-10 38.5 0.0 1.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM42925.1 - 9e-09 35.9 0.0 2.4e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM42925.1 - 1.1e-07 32.4 0.0 6.3e-07 30.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM42925.1 - 1.4e-07 31.5 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM42925.1 - 2.2e-07 31.5 0.0 4.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM42925.1 - 1.9e-05 24.1 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 GAM42925.1 - 0.00051 19.8 0.0 0.00059 19.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_33 PF10017.9 GAM42925.1 - 0.00059 19.1 0.0 0.015 14.5 0.0 2.1 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_32 PF13679.6 GAM42925.1 - 0.00062 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 GAM42925.1 - 0.0057 16.2 0.0 0.0095 15.4 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_7 PF03492.15 GAM42925.1 - 0.017 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase TehB PF03848.14 GAM42925.1 - 0.022 14.1 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Gyro_capsid PF04162.12 GAM42925.1 - 0.17 10.3 0.2 0.23 9.9 0.2 1.2 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) p450 PF00067.22 GAM42926.1 - 8.5e-36 123.7 0.3 1.4e-35 122.9 0.3 1.3 1 0 0 1 1 1 1 Cytochrome P450 Thioredoxin_7 PF13899.6 GAM42926.1 - 0.03 14.5 0.0 13 6.0 0.0 3.3 3 0 0 3 3 3 0 Thioredoxin-like Mit_KHE1 PF10173.9 GAM42927.1 - 1.3e-63 214.6 1.8 1.9e-63 214.0 1.8 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related MARVEL PF01284.23 GAM42928.1 - 0.0041 17.2 3.0 0.0062 16.6 3.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Cupin_2 PF07883.11 GAM42929.1 - 3.4e-08 33.1 0.1 5.9e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 GAM42929.1 - 7.5e-07 28.9 0.1 1.1e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 GAM42929.1 - 0.00078 19.2 0.0 0.00095 18.9 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 GAM42929.1 - 0.0094 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.14 GAM42929.1 - 0.02 15.1 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cupin_3 PF05899.12 GAM42929.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cullin PF00888.22 GAM42930.1 - 7.2e-193 642.6 11.9 1e-192 642.1 11.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAM42930.1 - 1.1e-26 92.6 4.0 4.4e-26 90.7 4.0 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain AnfG_VnfG PF03139.15 GAM42930.1 - 0.77 9.9 11.3 0.037 14.1 1.6 3.4 3 1 1 4 4 4 0 Vanadium/alternative nitrogenase delta subunit Phosphorylase PF00343.20 GAM42931.1 - 0 1057.7 0.0 0 1057.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.6 GAM42931.1 - 0.12 12.4 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform G-alpha PF00503.20 GAM42932.1 - 2.5e-113 378.9 0.5 2.8e-113 378.7 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM42932.1 - 3.2e-15 56.0 0.8 2.6e-10 40.0 0.3 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM42932.1 - 3.5e-05 23.3 0.2 0.063 12.6 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GAM42932.1 - 0.0033 17.6 0.3 0.86 9.8 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 GAM42932.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Avl9 PF09794.9 GAM42933.1 - 1.7e-109 366.0 0.0 2.8e-56 190.9 0.0 2.2 1 1 1 2 2 2 2 Transport protein Avl9 Pkinase PF00069.25 GAM42933.1 - 1.7e-65 221.0 0.0 2.5e-65 220.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM42933.1 - 3e-30 105.3 0.0 5.1e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAM42933.1 - 4e-05 22.7 0.1 8.7e-05 21.6 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAM42933.1 - 0.00088 18.7 0.0 0.0028 17.0 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2347 PF09804.9 GAM42933.1 - 0.0017 18.0 1.1 0.045 13.3 0.0 3.1 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2347) APH PF01636.23 GAM42933.1 - 0.004 17.1 0.0 0.0097 15.8 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAM42933.1 - 0.0055 16.1 0.0 0.26 10.6 0.0 2.2 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 GAM42933.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 GAM42933.1 - 0.19 11.3 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Afi1 PF07792.12 GAM42933.1 - 1.4 9.4 0.0 1.4 9.4 0.0 3.2 3 1 0 3 3 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking ABC_membrane_2 PF06472.15 GAM42934.1 - 3e-103 344.9 0.9 4.6e-103 344.3 0.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GAM42934.1 - 7.9e-18 65.3 0.0 1.6e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM42934.1 - 8.7e-05 22.5 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAM42934.1 - 0.0049 17.4 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GAM42934.1 - 0.017 14.8 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 GAM42934.1 - 0.051 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 GAM42934.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RuvB_N PF05496.12 GAM42934.1 - 0.14 11.9 0.1 1.6 8.4 0.0 2.6 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_15 PF13175.6 GAM42934.1 - 0.17 11.6 0.1 0.42 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Fungal_trans PF04082.18 GAM42935.1 - 4.3e-06 26.0 0.6 8.3e-06 25.0 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain PRORP PF16953.5 GAM42935.1 - 0.15 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-only RNase P DJ-1_PfpI PF01965.24 GAM42936.1 - 8e-12 45.3 0.0 1.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family LRR_6 PF13516.6 GAM42937.1 - 0.00045 20.1 1.8 11 6.4 0.0 5.6 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 GAM42937.1 - 0.0015 18.9 5.4 8.1 7.0 0.1 5.4 4 2 0 5 5 5 2 Leucine Rich repeats (2 copies) CDC45 PF02724.14 GAM42937.1 - 0.13 10.5 3.1 0.26 9.5 3.1 1.5 1 0 0 1 1 1 0 CDC45-like protein LRR_1 PF00560.33 GAM42937.1 - 6.8 7.7 7.6 75 4.5 0.1 5.5 6 1 0 6 6 6 0 Leucine Rich Repeat Ribosomal_L5e PF17144.4 GAM42938.1 - 1.1e-79 266.1 0.6 2e-79 265.3 0.6 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 GAM42938.1 - 7.4e-34 116.6 8.7 7.4e-34 116.6 8.7 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 GAM42938.1 - 0.023 15.1 0.2 0.049 14.0 0.2 1.5 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Thr_synth_N PF14821.6 GAM42938.1 - 0.041 14.1 0.2 1.3 9.3 0.0 2.8 2 1 0 2 2 2 0 Threonine synthase N terminus Colicin_immun PF09204.10 GAM42938.1 - 0.11 13.1 1.4 0.27 11.8 0.1 2.4 3 1 0 3 3 3 0 Bacterial self-protective colicin-like immunity HAD_2 PF13419.6 GAM42939.1 - 3.7e-06 27.1 0.0 6.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM42939.1 - 0.0061 16.6 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAM42939.1 - 0.026 14.8 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FTA4 PF13093.6 GAM42940.1 - 7.1e-55 186.0 8.0 1.5e-54 185.0 8.0 1.5 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF98 PF01947.16 GAM42940.1 - 0.024 14.6 0.2 0.067 13.2 0.2 1.7 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase RRF_GI PF12614.8 GAM42940.1 - 0.035 14.3 0.9 0.16 12.1 0.1 2.3 2 0 0 2 2 2 0 Ribosome recycling factor DUF4047 PF13256.6 GAM42940.1 - 0.04 14.1 1.1 0.1 12.8 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) MFS_1 PF07690.16 GAM42942.1 - 3.6e-31 108.4 44.2 7.6e-30 104.0 24.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 GAM42943.1 - 7.7e-46 156.7 0.2 1.2e-45 156.0 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 GAM42943.1 - 2e-21 76.1 0.0 3.7e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 GAM42943.1 - 1.5e-17 63.9 3.6 6.9e-17 61.8 0.9 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 GAM42943.1 - 1.6e-16 60.1 0.0 5e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 GAM42943.1 - 1.5e-15 56.9 0.1 5.9e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Fer2_BFD PF04324.15 GAM42943.1 - 1.6e-15 57.2 8.3 1.8e-12 47.4 5.6 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 GAM42943.1 - 5.5e-09 35.7 0.0 1.4e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 GAM42943.1 - 1.7e-05 24.6 3.8 0.031 14.2 0.2 3.8 4 0 0 4 4 4 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 GAM42943.1 - 0.0045 17.0 0.1 5.6 6.9 0.0 3.6 3 1 1 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.14 GAM42943.1 - 0.14 10.8 0.0 5.2 5.6 0.0 2.5 2 0 0 2 2 2 0 HI0933-like protein Mo-co_dimer PF03404.16 GAM42944.1 - 1.5e-59 200.0 0.0 3.2e-59 198.9 0.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 GAM42944.1 - 1.1e-53 181.4 0.0 1.7e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain NAD_binding_1 PF00175.21 GAM42944.1 - 8.3e-32 110.1 0.0 1.8e-31 109.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAM42944.1 - 1.2e-31 109.0 0.0 2e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 GAM42944.1 - 1e-17 64.0 0.0 2.4e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 GAM42944.1 - 0.0081 16.3 0.1 0.038 14.1 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain GCP_C_terminal PF04130.13 GAM42945.1 - 2.2e-68 231.0 0.1 3.2e-68 230.5 0.1 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GAM42945.1 - 9.3e-45 153.6 0.0 1.6e-44 152.8 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF4003 PF13170.6 GAM42945.1 - 0.069 12.5 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Eaf7 PF07904.13 GAM42946.1 - 3.2e-29 101.4 0.0 3.2e-29 101.4 0.0 2.3 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 NOA36 PF06524.12 GAM42946.1 - 1.7 7.9 9.2 4.1 6.7 9.2 1.6 1 0 0 1 1 1 0 NOA36 protein Spt5_N PF11942.8 GAM42946.1 - 6.6 7.8 19.5 12 7.0 14.3 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DNA_pol_phi PF04931.13 GAM42946.1 - 8.5 4.3 15.3 13 3.7 15.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Iso_dh PF00180.20 GAM42947.1 - 2.8e-100 335.9 0.0 3.4e-100 335.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 GAM42947.1 - 0.022 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 HHH_2 PF12826.7 GAM42947.1 - 0.031 14.4 0.0 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sec5 PF15469.6 GAM42948.1 - 1.1e-37 129.7 0.0 3.1e-37 128.3 0.0 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 GAM42948.1 - 1.7e-05 24.8 0.0 6.7e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 Vps51/Vps67 rRNA_processing PF08524.11 GAM42949.1 - 0.1 12.6 30.1 0.22 11.5 26.1 2.8 1 1 1 2 2 2 0 rRNA processing DUF1619 PF07773.11 GAM42949.1 - 0.18 11.7 0.1 0.27 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1619) DUF4210 PF13915.6 GAM42950.1 - 7.7e-33 112.9 1.6 1.6e-32 111.9 0.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 GAM42950.1 - 7.7e-25 86.8 0.4 1.7e-24 85.7 0.4 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis CAP_N PF01213.19 GAM42951.1 - 3.9e-114 381.4 0.1 3.9e-114 381.4 0.1 1.5 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 GAM42951.1 - 5.3e-55 185.3 1.3 7.6e-55 184.8 1.3 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DEC-1_N PF04625.13 GAM42951.1 - 0.51 9.3 22.4 0.31 10.0 13.0 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region PfkB PF00294.24 GAM42952.1 - 3e-11 43.2 0.0 3.7e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase dsrm PF00035.26 GAM42954.1 - 9.8e-08 32.6 0.0 1.9e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 GAM42954.1 - 6.4e-06 26.7 0.0 3.1e-05 24.5 0.0 2.2 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GAM42954.1 - 4.4e-05 23.7 0.0 0.0062 16.7 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease-III-like BSP PF04450.12 GAM42955.1 - 8.7e-72 241.2 0.0 1e-71 241.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_M91 PF14891.6 GAM42955.1 - 0.0022 18.3 0.0 0.0038 17.6 0.0 1.4 1 0 0 1 1 1 1 Effector protein Peptidase_M76 PF09768.9 GAM42955.1 - 0.018 14.8 0.2 0.027 14.3 0.2 1.2 1 0 0 1 1 1 0 Peptidase M76 family CLASP_N PF12348.8 GAM42956.1 - 9.9e-158 522.5 0.3 1.3e-92 309.5 0.0 2.4 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 GAM42956.1 - 4.2e-05 23.4 1.0 7.9 7.0 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 GAM42956.1 - 0.0023 18.0 0.0 0.8 9.7 0.0 3.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM42956.1 - 0.0069 16.8 2.9 1.4 9.3 0.2 4.8 4 1 1 5 5 5 1 HEAT repeats UME PF08064.13 GAM42956.1 - 0.025 14.5 0.0 0.22 11.5 0.0 2.5 3 0 0 3 3 3 0 UME (NUC010) domain DUF3361 PF11841.8 GAM42956.1 - 0.054 13.4 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) RhoGAP PF00620.27 GAM42957.1 - 1.2e-48 164.7 0.0 4.2e-48 163.0 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 GAM42957.1 - 0.0004 20.5 8.1 0.0004 20.5 8.1 2.5 2 0 0 2 2 2 1 LIM domain NAP PF00956.18 GAM42957.1 - 0.0065 15.7 1.4 0.026 13.7 0.8 2.2 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Zn-ribbon_8 PF09723.10 GAM42957.1 - 0.036 14.2 10.8 0.9 9.7 1.5 3.5 3 0 0 3 3 3 0 Zinc ribbon domain CENP-O PF09496.10 GAM42957.1 - 0.048 13.6 5.5 0.41 10.6 0.7 2.5 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component TF_Zn_Ribbon PF08271.12 GAM42957.1 - 0.35 10.4 12.5 1.6 8.3 1.0 4.3 3 1 1 4 4 4 0 TFIIB zinc-binding zf-C3HC4_3 PF13920.6 GAM42957.1 - 8.5 6.3 12.7 2.9 7.8 4.5 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DASH_Ask1 PF08655.10 GAM42958.1 - 5.6e-31 106.2 0.2 9.2e-31 105.5 0.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 MoCF_biosynth PF00994.24 GAM42958.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Probable molybdopterin binding domain LicD PF04991.13 GAM42961.1 - 3.3e-23 83.0 5.8 1.3e-15 58.2 1.5 2.2 1 1 1 2 2 2 2 LicD family Thiolase_N PF00108.23 GAM42962.1 - 1.1e-70 238.0 0.2 2.3e-70 237.0 0.1 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAM42962.1 - 2.8e-42 143.3 0.9 7.7e-42 141.8 0.2 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAM42962.1 - 3.3e-05 23.6 0.4 0.00036 20.2 0.3 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 GAM42962.1 - 0.024 14.5 0.3 3.7 7.5 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HSP70 PF00012.20 GAM42963.1 - 9.9e-170 565.6 1.8 9.9e-170 565.6 1.8 2.0 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 GAM42963.1 - 1.1e-09 37.5 0.1 2.8e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 GAM42963.1 - 0.015 15.7 0.4 9.1 6.8 0.0 3.4 2 2 0 2 2 2 0 Cell division protein FtsA Ketoacyl-synt_C PF02801.22 GAM42963.1 - 0.045 13.8 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain FGGY_C PF02782.16 GAM42963.1 - 0.099 12.4 0.2 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF4288 PF14119.6 GAM42963.1 - 0.25 11.8 3.0 0.62 10.5 3.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) Chitin_synth_2 PF03142.15 GAM42964.1 - 1.1e-22 80.4 3.9 3.3e-21 75.5 4.3 2.3 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 GAM42964.1 - 3.8e-12 46.5 9.9 3.8e-12 46.5 9.9 2.7 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAM42964.1 - 2.7e-10 40.5 0.0 4.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAM42964.1 - 0.00081 19.2 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 La PF05383.17 GAM42965.1 - 2.7e-20 72.2 0.0 4.6e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 GAM42965.1 - 3.8e-07 29.8 0.1 7.6e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dabb PF07876.12 GAM42966.1 - 2.8e-10 40.7 0.0 3.1e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain FSH1 PF03959.13 GAM42967.1 - 2.4e-31 109.1 0.0 3e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 GAM42967.1 - 1.8e-06 28.7 0.2 2.2e-06 28.5 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM42967.1 - 0.06 13.0 0.4 0.23 11.1 0.2 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold ketoacyl-synt PF00109.26 GAM42968.1 - 1.1e-67 228.3 0.0 1.8e-67 227.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAM42968.1 - 1.2e-62 211.0 0.5 1e-61 208.0 0.2 2.5 3 0 0 3 3 2 1 KR domain PS-DH PF14765.6 GAM42968.1 - 1.3e-38 133.0 0.0 2e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 GAM42968.1 - 1e-37 128.7 0.0 3e-37 127.2 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 GAM42968.1 - 1.7e-21 77.1 0.1 4.1e-12 46.2 0.0 2.9 1 1 1 2 2 2 2 Acyl transferase domain Methyltransf_12 PF08242.12 GAM42968.1 - 1.2e-19 70.9 0.0 2.9e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM42968.1 - 2e-14 54.0 0.0 9.6e-14 51.9 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM42968.1 - 3.6e-13 49.6 0.0 1.1e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM42968.1 - 7.5e-13 48.9 0.0 2.1e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM42968.1 - 8.5e-13 48.5 0.0 2.4e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 GAM42968.1 - 1e-10 41.4 0.2 3e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 GAM42968.1 - 7.6e-09 35.8 0.0 1.9e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 GAM42968.1 - 1.5e-08 35.0 0.0 8e-08 32.7 0.0 2.3 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Ubie_methyltran PF01209.18 GAM42968.1 - 1.7e-08 34.1 0.0 4.3e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 GAM42968.1 - 2.6e-06 27.2 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_28 PF02636.17 GAM42968.1 - 0.00033 20.4 0.0 0.00064 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 GAM42968.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_24 PF13578.6 GAM42968.1 - 0.0031 18.5 0.0 0.013 16.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 GAM42968.1 - 0.0067 16.2 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Thiolase_N PF00108.23 GAM42968.1 - 0.01 15.3 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 GAM42968.1 - 0.024 13.8 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_33 PF10017.9 GAM42968.1 - 0.025 13.8 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent SUI1 PF01253.22 GAM42969.1 - 8.6e-23 80.7 1.0 1.9e-22 79.6 0.5 1.9 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 GAM42969.1 - 4.6e-08 33.6 0.0 4e-06 27.4 0.0 2.8 1 1 0 1 1 1 1 Pre-PUA-like domain Kin17_mid PF10357.9 GAM42969.1 - 0.061 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein Glyco_hydro_61 PF03443.14 GAM42970.1 - 4.8e-70 235.7 0.2 7.1e-70 235.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TIG PF01833.24 GAM42971.1 - 5.4e-10 39.2 1.6 1.9e-09 37.5 0.6 2.5 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.6 GAM42971.1 - 5.7e-10 39.3 0.3 2.6e-05 24.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM42971.1 - 9e-07 29.4 0.0 1.7e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAM42971.1 - 2.6e-06 27.6 1.3 0.058 13.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 GAM42971.1 - 8.3e-06 26.3 0.1 2.3e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM42971.1 - 0.00051 20.3 0.2 0.89 10.3 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat DUF2157 PF09925.9 GAM42971.1 - 0.21 11.4 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) TRAPPC10 PF12584.8 GAM42972.1 - 4.2e-38 130.5 0.0 7.1e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 GAM42972.1 - 0.031 13.8 1.8 0.043 13.4 0.2 2.0 2 0 0 2 2 2 0 Foie gras liver health family 1 Glyco_hydro_18 PF00704.28 GAM42973.1 - 3.2e-40 138.8 1.8 3.2e-40 138.8 1.8 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.20 GAM42973.1 - 4.1e-06 26.8 0.3 1e-05 25.5 0.3 1.8 1 0 0 1 1 1 1 LysM domain Chitin_bind_1 PF00187.19 GAM42973.1 - 7.8e-05 23.1 11.1 7.8e-05 23.1 11.1 3.1 2 1 0 2 2 2 1 Chitin recognition protein Aspzincin_M35 PF14521.6 GAM42974.1 - 0.01 16.3 0.0 0.025 15.1 0.0 1.7 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase LysM PF01476.20 GAM42975.1 - 5e-25 87.3 0.0 0.0002 21.3 0.0 5.3 5 0 0 5 5 5 5 LysM domain HTH_Tnp_1 PF01527.20 GAM42975.1 - 0.017 15.4 0.0 55 4.2 0.0 4.0 4 0 0 4 4 4 0 Transposase Cauli_VI PF01693.16 GAM42975.1 - 0.035 14.4 0.0 1.1e+02 3.3 0.0 4.2 4 0 0 4 4 4 0 Caulimovirus viroplasmin Tox-ODYAM1 PF15642.6 GAM42975.1 - 0.046 12.7 0.0 11 4.9 0.0 3.5 4 0 0 4 4 4 0 Toxin in Odyssella and Amoebophilus Rad51 PF08423.11 GAM42977.1 - 1.9e-44 151.8 0.0 5.3e-41 140.6 0.0 2.1 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 GAM42977.1 - 2.4e-11 43.6 0.0 3.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GAM42977.1 - 3.7e-09 36.3 0.0 1.4e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 KaiC RecA PF00154.21 GAM42977.1 - 2.2e-05 24.1 0.1 0.0013 18.2 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 GAM42977.1 - 0.0015 17.9 0.3 0.075 12.3 0.1 2.7 2 1 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 GAM42977.1 - 0.0024 18.1 0.0 0.0044 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 GAM42977.1 - 0.032 13.7 0.2 0.062 12.8 0.2 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein NACHT PF05729.12 GAM42977.1 - 0.17 11.8 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FA_desaturase PF00487.24 GAM42978.1 - 2.6e-23 83.2 21.6 8.5e-23 81.5 21.6 1.8 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 GAM42978.1 - 6.1e-07 29.7 0.0 1.6e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Cyclase PF04199.13 GAM42979.1 - 0.00015 22.0 0.0 0.00024 21.4 0.0 1.4 1 1 0 1 1 1 1 Putative cyclase PDZ_6 PF17820.1 GAM42979.1 - 0.056 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 PDZ domain adh_short PF00106.25 GAM42981.1 - 2.7e-33 115.1 0.0 3.4e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM42981.1 - 4.8e-17 62.3 0.0 6.3e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM42981.1 - 5.1e-07 29.8 0.6 1e-06 28.8 0.2 1.9 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 GAM42981.1 - 0.00062 19.7 0.1 0.001 19.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM42981.1 - 0.0016 17.9 0.1 0.0023 17.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAM42981.1 - 0.0022 18.1 0.0 0.0074 16.4 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 GAM42981.1 - 0.0043 16.6 0.1 0.0066 16.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 GAM42981.1 - 0.021 15.1 0.1 0.04 14.2 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1776 PF08643.10 GAM42981.1 - 0.033 13.6 0.1 0.093 12.1 0.1 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 GAM42981.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Fungal_trans PF04082.18 GAM42982.1 - 8.5e-05 21.7 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_62 PF03664.13 GAM42983.1 - 5.7e-136 452.2 10.6 6.6e-136 452.0 10.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 DUF3598 PF12204.8 GAM42983.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) AsnC_trans_reg PF01037.21 GAM42983.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.2 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain Questin_oxidase PF14027.6 GAM42984.1 - 1.2e-75 255.2 0.2 1.4e-75 254.9 0.2 1.1 1 0 0 1 1 1 1 Questin oxidase-like NAD_binding_10 PF13460.6 GAM42985.1 - 4.2e-15 56.1 0.0 1.6e-14 54.2 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM42985.1 - 4.2e-05 23.2 0.0 6.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 GAM42985.1 - 0.0016 18.7 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 GAM42985.1 - 0.0026 16.8 0.0 0.0034 16.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAM42985.1 - 0.066 12.4 0.0 0.16 11.1 0.1 1.7 2 1 0 2 2 2 0 Male sterility protein Semialdhyde_dh PF01118.24 GAM42985.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 GAM42985.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Aldolase_II PF00596.21 GAM42986.1 - 3.2e-09 37.0 0.1 5e-09 36.3 0.1 1.4 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain AA_permease_2 PF13520.6 GAM42987.1 - 1.8e-61 208.3 54.8 2.2e-61 208.0 54.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM42987.1 - 4e-33 114.7 49.6 5.3e-33 114.3 49.6 1.0 1 0 0 1 1 1 1 Amino acid permease JmjC PF02373.22 GAM42988.1 - 3.7e-37 127.3 0.8 7.6e-37 126.2 0.4 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 GAM42988.1 - 6.6e-19 68.1 2.7 1.2e-18 67.2 2.7 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GAM42988.1 - 8.1e-19 67.7 2.8 1.9e-18 66.5 2.8 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.17 GAM42988.1 - 1.5e-15 56.9 0.6 4e-15 55.5 0.6 1.8 1 0 0 1 1 1 1 jmjN domain AA_permease PF00324.21 GAM42989.1 - 4.6e-118 394.9 45.0 5.5e-118 394.6 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM42989.1 - 2.4e-29 102.4 45.9 3.1e-29 102.0 45.9 1.0 1 0 0 1 1 1 1 Amino acid permease Alpha-amylase_C PF02806.18 GAM42990.1 - 8.3e-28 96.7 0.1 1.8e-27 95.6 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 GAM42990.1 - 6.2e-19 68.2 0.0 1.8e-18 66.7 0.0 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 GAM42990.1 - 9.8e-16 58.2 0.0 1.6e-11 44.3 0.1 2.4 1 1 0 2 2 2 2 Alpha amylase, catalytic domain Carn_acyltransf PF00755.20 GAM42991.1 - 1.7e-208 694.0 0.0 2.5e-208 693.5 0.0 1.2 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Glyco_hydro_92 PF07971.12 GAM42992.1 - 4.9e-140 467.5 1.9 6.2e-140 467.2 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 GAM42992.1 - 7.5e-50 170.0 6.0 1.1e-49 169.5 6.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain DUF4576 PF15144.6 GAM42992.1 - 0.058 13.3 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) UPF0160 PF03690.13 GAM42993.1 - 6.3e-124 413.7 0.0 7.1e-124 413.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ODV-E18 PF10717.9 GAM42994.1 - 0.07 13.0 0.3 5.7 6.9 0.0 2.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Ras PF00071.22 GAM42995.1 - 2e-62 209.5 0.2 2.5e-62 209.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM42995.1 - 1.7e-34 118.6 0.2 2.5e-34 118.1 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM42995.1 - 4.5e-12 45.8 0.1 6.1e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM42995.1 - 1.5e-07 31.5 0.1 2.4e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM42995.1 - 8.3e-05 22.5 0.2 0.0077 16.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 GAM42995.1 - 0.00066 19.3 0.2 0.0033 17.0 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 GAM42995.1 - 0.0011 19.2 0.0 0.0086 16.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 GAM42995.1 - 0.0023 17.3 0.1 0.0039 16.6 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 GAM42995.1 - 0.0071 16.4 0.2 0.022 14.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM42995.1 - 0.012 16.0 0.1 0.019 15.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 GAM42995.1 - 0.016 14.6 0.0 0.027 13.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 GAM42995.1 - 0.022 15.3 0.1 0.032 14.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 GAM42995.1 - 0.032 13.9 0.1 0.083 12.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 GAM42995.1 - 0.059 12.8 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 GAM42995.1 - 0.073 12.9 0.7 0.1 12.4 0.6 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 GAM42995.1 - 0.12 11.9 0.1 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 GAM42995.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region GMC_oxred_N PF00732.19 GAM42996.1 - 3.9e-73 246.4 0.1 5.3e-73 246.0 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM42996.1 - 2e-23 83.5 0.0 3.5e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAM42996.1 - 0.00036 19.8 0.0 0.00078 18.6 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM42996.1 - 0.0004 20.5 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAM42996.1 - 0.00046 19.5 0.0 0.00096 18.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 GAM42996.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAM42996.1 - 0.042 12.9 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Fas_alpha_ACP PF18325.1 GAM42997.1 - 4.1e-57 193.0 1.0 7e-57 192.3 0.2 1.9 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 GAM42997.1 - 3.4e-47 160.7 0.0 7.6e-47 159.6 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 GAM42997.1 - 3.2e-20 72.8 0.1 9.9e-20 71.2 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAM42997.1 - 5.3e-10 39.4 0.0 1.8e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 GAM42997.1 - 1.3e-07 31.3 0.1 1.9e-06 27.5 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase Vir_act_alpha_C PF10400.9 GAM42997.1 - 1 10.1 3.1 1.4 9.7 0.1 2.5 2 0 0 2 2 2 0 Virulence activator alpha C-term DUF1729 PF08354.10 GAM42998.1 - 7.3e-142 472.4 0.0 1.2e-141 471.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 GAM42998.1 - 1.7e-57 195.3 0.0 7.7e-55 186.6 0.0 3.8 3 1 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 GAM42998.1 - 2.5e-39 134.4 0.0 6.9e-39 133.0 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 GAM42998.1 - 8.8e-35 120.6 0.1 3.1e-34 118.8 0.0 1.9 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 GAM42998.1 - 7.8e-31 106.2 0.0 2.6e-30 104.5 0.0 1.9 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 GAM42998.1 - 4.9e-24 84.9 0.0 1.3e-23 83.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase FAS_N PF17828.1 GAM42998.1 - 1.6e-08 34.6 0.0 4.4e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Pertussis_S2S3 PF02918.15 GAM42998.1 - 0.011 15.6 0.0 0.051 13.5 0.0 2.1 2 0 0 2 2 2 0 Pertussis toxin, subunit 2 and 3, C-terminal domain NMO PF03060.15 GAM42998.1 - 0.049 13.0 0.8 0.8 9.0 0.8 2.4 1 1 0 1 1 1 0 Nitronate monooxygenase Ank_2 PF12796.7 GAM42999.1 - 1.5e-22 80.0 4.7 5.8e-19 68.5 1.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM42999.1 - 1.9e-18 66.6 0.6 5.3e-10 39.6 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAM42999.1 - 3.2e-18 65.3 2.9 3.5e-06 27.2 0.6 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 GAM42999.1 - 2.7e-15 56.2 3.4 1.5e-07 31.5 0.9 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM42999.1 - 4.3e-15 54.3 0.5 0.00032 20.9 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.21 GAM42999.1 - 0.2 11.8 5.6 0.23 11.6 4.4 1.7 2 0 0 2 2 2 0 bZIP transcription factor FAD_binding_3 PF01494.19 GAM43000.1 - 2e-73 247.7 0.0 2.7e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAM43000.1 - 1.7e-05 24.9 0.0 4.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 GAM43000.1 - 4.7e-05 23.1 0.3 0.0044 16.6 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM43000.1 - 0.00025 20.3 0.4 0.0052 15.9 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 GAM43000.1 - 0.0063 15.9 0.4 0.035 13.5 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM43000.1 - 0.0087 15.3 0.0 0.021 14.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM43000.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM43000.1 - 0.079 11.7 0.2 0.17 10.5 0.2 1.5 1 0 0 1 1 1 0 HI0933-like protein p450 PF00067.22 GAM43001.1 - 8.8e-60 202.7 0.0 1.1e-59 202.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyl-CoA_dh_1 PF00441.24 GAM43002.1 - 4e-20 72.5 0.3 9.8e-20 71.3 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAM43002.1 - 3.3e-13 49.6 0.0 8.1e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AidB_N PF18158.1 GAM43002.1 - 1.7e-10 41.0 0.0 3.7e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAM43002.1 - 4.1e-06 27.1 1.0 1.4e-05 25.4 1.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TryThrA_C PF12319.8 GAM43002.1 - 0.0046 16.5 0.9 0.0092 15.5 0.9 1.4 1 0 0 1 1 1 1 Tryptophan-Threonine-rich plasmodium antigen C terminal NAD_binding_1 PF00175.21 GAM43003.1 - 2.7e-33 114.9 0.0 4.4e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAM43003.1 - 1.7e-27 95.6 0.0 3.5e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 GAM43003.1 - 2.8e-19 69.0 0.1 5e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 GAM43003.1 - 1e-06 29.0 0.0 0.00019 21.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DUF829 PF05705.14 GAM43004.1 - 3.1e-42 145.1 0.0 3.8e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) MFS_1 PF07690.16 GAM43005.1 - 4.3e-41 141.0 43.2 4.3e-41 141.0 43.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 GAM43005.1 - 0.0042 15.4 1.8 0.0042 15.4 1.8 2.6 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 GAM43006.1 - 1e-06 28.0 0.6 1.7e-06 27.3 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM43006.1 - 0.0005 20.1 11.1 0.00082 19.4 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_31 PF01055.26 GAM43007.1 - 1.2e-35 123.5 3.1 3.1e-23 82.7 0.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 GAM43007.1 - 2e-33 115.0 0.0 3.6e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 GAM43007.1 - 0.0014 18.9 0.1 0.022 15.0 0.1 2.8 4 0 0 4 4 4 1 Galactose mutarotase-like Alpha-amylase PF00128.24 GAM43008.1 - 5e-67 226.8 0.9 6.9e-67 226.4 0.9 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 GAM43008.1 - 2.7e-36 123.7 0.4 6.8e-36 122.4 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) CBM_20 PF00686.19 GAM43008.1 - 8.5e-35 118.6 0.4 2.1e-34 117.3 0.4 1.6 1 0 0 1 1 1 1 Starch binding domain AMPK1_CBM PF16561.5 GAM43008.1 - 0.0052 17.0 0.1 0.014 15.6 0.1 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Curlin_rpt PF07012.12 GAM43008.1 - 0.082 12.9 0.7 0.21 11.6 0.7 1.7 1 0 0 1 1 1 0 Curlin associated repeat Chromo PF00385.24 GAM43009.1 - 1.1e-08 34.9 1.6 2.3e-08 33.8 1.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_2 PF07724.14 GAM43010.1 - 1.6e-38 132.5 0.0 1.5e-37 129.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 GAM43010.1 - 1.5e-14 54.6 0.0 2.9e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GAM43010.1 - 2.7e-09 36.9 0.1 8.9e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GAM43010.1 - 1.5e-06 28.3 0.0 3.4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAM43010.1 - 0.00033 20.1 0.1 0.015 14.7 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 GAM43010.1 - 0.00034 20.4 0.0 0.071 12.8 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 GAM43010.1 - 0.002 18.4 0.1 0.019 15.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 GAM43010.1 - 0.003 16.7 0.1 0.0061 15.7 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 GAM43010.1 - 0.0035 17.7 0.1 0.014 15.8 0.1 1.8 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAM43010.1 - 0.0037 17.0 0.1 0.033 13.9 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 GAM43010.1 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 GAM43010.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM43010.1 - 0.037 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 GAM43010.1 - 0.04 13.8 0.1 0.12 12.2 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAM43010.1 - 0.061 13.7 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 GAM43010.1 - 0.093 12.9 0.4 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 GAM43010.1 - 0.099 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAM43010.1 - 0.1 13.1 0.0 0.28 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAM43010.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE F-box-like PF12937.7 GAM43011.1 - 0.0025 17.7 1.2 0.0055 16.6 0.4 2.1 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 GAM43011.1 - 0.006 16.5 0.0 0.013 15.5 0.0 1.7 1 1 0 1 1 1 1 F-box-like domain F-box PF00646.33 GAM43011.1 - 0.01 15.7 0.9 0.032 14.1 0.9 1.9 1 0 0 1 1 1 0 F-box domain Brix PF04427.18 GAM43012.1 - 3.6e-29 102.3 0.0 5.6e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain WW PF00397.26 GAM43012.1 - 3.6e-07 30.2 1.0 7.6e-07 29.1 1.0 1.6 1 0 0 1 1 1 1 WW domain Abp2 PF09441.10 GAM43015.1 - 5e-80 267.6 0.1 9.7e-80 266.6 0.1 1.5 2 0 0 2 2 2 1 ARS binding protein 2 F-box-like PF12937.7 GAM43016.1 - 0.0034 17.3 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like Cytomega_UL84 PF06284.11 GAM43017.1 - 0.15 10.5 1.0 0.19 10.1 1.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Ashwin PF15323.6 GAM43018.1 - 0.18 11.8 5.8 0.27 11.2 5.8 1.2 1 0 0 1 1 1 0 Developmental protein E2F_TDP PF02319.20 GAM43019.1 - 0.0048 16.9 0.2 0.0085 16.1 0.0 1.5 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Myb_DNA-binding PF00249.31 GAM43019.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAM43020.1 - 3.9e-05 23.7 0.0 8.8e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain Ank_2 PF12796.7 GAM43022.1 - 7e-49 164.4 10.9 4e-13 49.8 0.4 6.0 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM43022.1 - 5.3e-37 125.7 9.3 1.2e-06 29.0 0.3 8.3 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 GAM43022.1 - 1.8e-30 104.0 22.0 0.019 15.4 0.0 11.3 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.6 GAM43022.1 - 1.3e-23 80.5 8.2 0.31 11.7 0.0 11.4 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 GAM43022.1 - 2.6e-23 81.8 12.2 0.0039 17.5 0.0 10.6 3 3 8 11 11 11 7 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 GAM43022.1 - 2.9e-08 33.3 0.5 1.3e-07 31.2 0.5 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 GAM43022.1 - 2.9e-07 30.5 0.0 6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAM43022.1 - 0.0078 16.6 0.0 0.039 14.3 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 GAM43022.1 - 0.056 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PAS_11 PF14598.6 GAM43022.1 - 0.14 12.3 0.1 3 8.0 0.1 3.1 3 0 0 3 3 3 0 PAS domain AAA PF00004.29 GAM43022.1 - 0.17 12.3 0.0 0.76 10.2 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1843 PF08898.10 GAM43022.1 - 9.1 6.9 6.3 29 5.3 0.0 4.2 4 1 1 5 5 4 0 Domain of unknown function (DUF1843) Glyco_hydro_31 PF01055.26 GAM43023.1 - 5.7e-87 292.7 3.0 5.2e-81 273.1 0.7 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GAM43023.1 - 2.8e-18 66.0 0.0 4.8e-17 62.0 0.1 2.9 3 0 0 3 3 3 1 Galactose mutarotase-like PAP_assoc PF03828.19 GAM43024.1 - 7.5e-12 45.3 0.1 7.5e-12 45.3 0.1 1.8 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAM43024.1 - 3.2e-07 30.5 0.0 7.8e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain GFA PF04828.14 GAM43025.1 - 7.8e-16 58.2 16.7 1.8e-11 44.2 0.5 3.5 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme PRKCSH_1 PF13015.6 GAM43026.1 - 3.7e-34 117.6 3.3 7.5e-33 113.4 0.9 2.9 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH-like PF12999.7 GAM43026.1 - 2.5e-30 105.5 5.6 2.6e-28 99.0 0.3 2.9 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH PF07915.13 GAM43026.1 - 4e-09 37.4 0.2 1.4e-08 35.6 0.2 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG16 PF08614.11 GAM43026.1 - 0.0012 19.1 3.3 0.0012 19.1 3.3 3.1 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) ATG27 PF09451.10 GAM43026.1 - 0.007 16.2 1.3 0.015 15.2 1.3 1.5 1 0 0 1 1 1 1 Autophagy-related protein 27 Fib_alpha PF08702.10 GAM43026.1 - 0.022 15.0 8.4 1.3 9.2 0.0 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Herpes_UL6 PF01763.16 GAM43026.1 - 0.18 10.3 0.7 0.3 9.6 0.7 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like CASP_C PF08172.12 GAM43026.1 - 1.3 8.3 11.4 0.32 10.3 7.6 1.9 2 1 0 2 2 2 0 CASP C terminal Spc7 PF08317.11 GAM43026.1 - 1.5 7.6 16.8 1.8 7.4 0.1 3.0 3 0 0 3 3 3 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 GAM43026.1 - 1.9 9.1 10.6 2 9.0 0.2 3.4 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Spc24 PF08286.11 GAM43026.1 - 2 8.7 9.8 13 6.0 2.0 3.4 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DUF16 PF01519.16 GAM43026.1 - 3.4 8.2 9.9 0.4 11.2 2.4 2.6 3 0 0 3 3 2 0 Protein of unknown function DUF16 SlyX PF04102.12 GAM43026.1 - 4.2 8.0 7.4 25 5.6 0.1 2.9 3 0 0 3 3 3 0 SlyX Tektin PF03148.14 GAM43026.1 - 7 5.3 18.2 3.6 6.2 0.2 3.1 3 0 0 3 3 3 0 Tektin family Rtf2 PF04641.12 GAM43027.1 - 1.3e-63 214.9 3.9 1.5e-63 214.6 3.9 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 GAM43027.1 - 4.6e-07 29.6 0.0 0.021 14.6 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 GAM43027.1 - 0.011 15.7 0.0 0.034 14.2 0.0 1.8 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 GAM43027.1 - 0.013 15.5 0.1 0.023 14.7 0.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAM43027.1 - 0.03 14.2 0.1 0.057 13.3 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM43027.1 - 0.083 13.2 0.1 0.18 12.1 0.1 1.6 1 1 0 1 1 1 0 Ring finger domain Alph_Pro_TM PF09608.10 GAM43027.1 - 0.18 11.6 0.2 0.25 11.1 0.2 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) zf-RING_11 PF17123.5 GAM43027.1 - 0.22 11.3 0.8 0.73 9.6 0.0 2.1 2 0 0 2 2 2 0 RING-like zinc finger Ribosomal_L50 PF10501.9 GAM43028.1 - 4e-19 68.8 0.0 9.2e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal subunit 39S DUF3306 PF11748.8 GAM43028.1 - 1.2 10.0 11.2 1.2 10.0 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Thiolase_N PF00108.23 GAM43029.1 - 1.6e-77 260.4 0.6 2.6e-77 259.7 0.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAM43029.1 - 8.5e-45 151.4 1.4 2.4e-44 149.9 0.7 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAM43029.1 - 0.011 15.3 0.3 0.051 13.2 0.2 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain DAHP_synth_1 PF00793.20 GAM43031.1 - 7.6e-100 333.3 0.0 9.4e-100 333.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Hexokinase_2 PF03727.16 GAM43033.1 - 2.3e-60 204.0 0.0 3.5e-60 203.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 GAM43033.1 - 3.4e-46 157.7 0.0 5.2e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Tom37_C PF11801.8 GAM43033.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Tom37 C-terminal domain AAA PF00004.29 GAM43035.1 - 3.7e-53 179.5 0.0 3.5e-43 147.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 GAM43035.1 - 2.4e-29 101.5 0.2 5.3e-29 100.4 0.2 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 GAM43035.1 - 4.3e-16 58.4 0.1 7.9e-09 35.2 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 GAM43035.1 - 1.7e-08 35.1 4.1 0.0017 18.8 0.2 4.1 2 2 1 3 3 3 2 AAA ATPase domain NACHT PF05729.12 GAM43035.1 - 2.3e-07 30.9 1.7 4.6e-05 23.4 0.1 3.2 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 GAM43035.1 - 3.7e-06 27.3 2.2 0.037 14.3 0.2 4.0 2 2 1 3 3 3 2 AAA domain TsaE PF02367.17 GAM43035.1 - 8e-06 25.9 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 GAM43035.1 - 1.2e-05 25.8 0.0 0.02 15.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 GAM43035.1 - 1.9e-05 24.9 0.0 0.15 12.2 0.0 2.6 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GAM43035.1 - 4.4e-05 23.3 0.0 0.016 15.0 0.0 2.8 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAM43035.1 - 0.00017 21.6 0.1 0.47 10.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GAM43035.1 - 0.00026 20.8 0.1 0.2 11.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 GAM43035.1 - 0.00032 20.7 0.0 0.48 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 GAM43035.1 - 0.00082 19.6 0.0 0.22 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GAM43035.1 - 0.0011 18.5 0.0 0.033 13.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 GAM43035.1 - 0.0014 19.2 0.8 0.29 11.7 0.0 3.0 3 0 0 3 3 2 1 ABC transporter Zeta_toxin PF06414.12 GAM43035.1 - 0.0023 17.2 0.0 0.57 9.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin KAP_NTPase PF07693.14 GAM43035.1 - 0.004 16.4 0.0 0.017 14.4 0.0 1.8 1 1 1 2 2 2 1 KAP family P-loop domain AAA_33 PF13671.6 GAM43035.1 - 0.0054 16.9 0.2 0.24 11.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain ATPase PF06745.13 GAM43035.1 - 0.0086 15.5 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 1 KaiC Mg_chelatase PF01078.21 GAM43035.1 - 0.0091 15.4 0.1 0.95 8.8 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 GAM43035.1 - 0.013 15.1 3.7 7.5 6.1 0.1 3.9 2 2 2 4 4 4 0 AAA domain AAA_17 PF13207.6 GAM43035.1 - 0.013 15.9 0.2 3 8.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAM43035.1 - 0.015 15.7 0.0 10 6.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 GAM43035.1 - 0.02 14.7 0.0 0.57 9.9 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 GAM43035.1 - 0.021 14.8 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 GAM43035.1 - 0.022 14.5 0.1 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TIP49 PF06068.13 GAM43035.1 - 0.036 13.3 0.1 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain PEX-2N PF09263.10 GAM43035.1 - 0.057 13.7 0.2 1.4 9.2 0.2 2.7 1 1 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal AAA_19 PF13245.6 GAM43035.1 - 0.087 13.2 0.2 0.83 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAM43035.1 - 0.097 12.6 0.0 3.1 7.6 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 GAM43035.1 - 0.14 11.2 0.0 1.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 GAM43035.1 - 0.16 11.7 0.2 1.5 8.6 0.3 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.19 GAM43035.1 - 0.28 10.8 1.8 2.1 7.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 GAM43036.1 - 1.9e-95 318.2 0.0 3.4e-95 317.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAM43036.1 - 3.8e-33 114.0 0.1 6.9e-33 113.2 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 GAM43036.1 - 7.4e-22 77.9 0.9 1.8e-21 76.6 0.9 1.7 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 GAM43036.1 - 8.5e-21 74.2 0.4 2.1e-20 72.9 0.4 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 GAM43036.1 - 3e-07 30.0 0.0 2e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAM43036.1 - 1.3e-06 28.5 0.0 3.9e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 GAM43036.1 - 0.00022 21.0 0.2 0.0033 17.2 0.0 2.6 2 0 0 2 2 2 1 AAA lid domain AAA_3 PF07726.11 GAM43036.1 - 0.023 14.5 0.0 0.078 12.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAM43036.1 - 0.15 11.7 0.0 0.75 9.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AMP-binding PF00501.28 GAM43037.1 - 2.1e-98 329.7 0.0 2.5e-98 329.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM43037.1 - 2.8e-09 37.8 0.4 6.3e-09 36.7 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phage_capsid PF05065.13 GAM43037.1 - 0.003 16.9 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 Phage capsid family Cu_amine_oxid PF01179.20 GAM43038.1 - 9.3e-164 545.2 0.1 1.1e-163 544.9 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 GAM43038.1 - 8.8e-05 22.8 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 GAM43038.1 - 0.0026 18.0 0.1 0.0059 16.8 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CMAS PF02353.20 GAM43039.1 - 8.8e-64 215.4 0.1 1.1e-63 215.1 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 GAM43039.1 - 9.1e-08 32.7 0.0 1.9e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM43039.1 - 1.8e-07 31.1 0.0 3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM43039.1 - 7.8e-07 29.7 0.0 1.7e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 GAM43039.1 - 0.0018 17.8 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 GAM43039.1 - 0.0037 18.0 0.0 0.0077 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM43039.1 - 0.062 13.1 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAM43039.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FSIP2 PF15783.5 GAM43040.1 - 0.88 7.4 3.8 1.3 6.9 3.8 1.1 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 Tropomyosin_1 PF12718.7 GAM43041.1 - 1.5e-51 174.3 32.7 1.7e-51 174.1 32.7 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 GAM43041.1 - 7.6e-09 35.3 31.4 2e-05 24.1 16.2 2.5 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.9 GAM43041.1 - 0.00012 22.2 21.0 0.00038 20.6 7.5 2.9 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein GAS PF13851.6 GAM43041.1 - 0.0021 17.4 29.4 0.0097 15.3 19.4 2.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Qua1 PF16274.5 GAM43041.1 - 0.0029 17.4 0.7 0.0029 17.4 0.7 2.8 2 1 1 3 3 2 1 Qua1 domain DUF4407 PF14362.6 GAM43041.1 - 0.0044 16.4 21.7 0.0048 16.3 15.6 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) Spc7 PF08317.11 GAM43041.1 - 0.0066 15.4 31.7 0.16 10.8 10.6 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein bZIP_1 PF00170.21 GAM43041.1 - 0.0071 16.4 26.8 0.22 11.7 0.3 4.3 2 1 2 4 4 4 2 bZIP transcription factor ATG16 PF08614.11 GAM43041.1 - 0.015 15.5 29.6 0.15 12.3 8.6 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ERM PF00769.19 GAM43041.1 - 0.016 15.0 14.8 0.016 15.0 14.8 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF724 PF05266.14 GAM43041.1 - 0.016 15.0 23.7 0.031 14.1 8.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TACC_C PF05010.14 GAM43041.1 - 0.021 14.6 25.5 0.1 12.4 18.0 2.3 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal APG6_N PF17675.1 GAM43041.1 - 0.022 15.3 38.4 0.19 12.3 19.5 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region BLOC1_2 PF10046.9 GAM43041.1 - 0.022 15.0 21.0 0.092 13.1 0.7 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.6 GAM43041.1 - 0.049 14.0 31.8 0.22 11.9 13.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Jnk-SapK_ap_N PF09744.9 GAM43041.1 - 0.06 13.6 30.8 0.044 14.0 20.7 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SOGA PF11365.8 GAM43041.1 - 0.067 14.3 22.7 1.6 9.9 9.6 3.5 2 1 1 3 3 3 0 Protein SOGA MAD PF05557.13 GAM43041.1 - 0.084 11.2 28.5 0.13 10.6 28.5 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein EzrA PF06160.12 GAM43041.1 - 0.096 10.8 23.9 0.09 10.9 8.4 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA ADIP PF11559.8 GAM43041.1 - 0.097 12.8 29.4 2.3 8.3 7.0 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Uso1_p115_C PF04871.13 GAM43041.1 - 0.12 12.7 32.8 1.1 9.6 12.9 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_TATA_bd PF12325.8 GAM43041.1 - 0.14 12.4 26.7 0.68 10.2 19.2 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 GAM43041.1 - 0.15 12.5 19.1 0.75 10.2 2.5 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 GAM43041.1 - 0.16 12.0 30.4 0.34 11.0 11.9 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus VGPC1_C PF16799.5 GAM43041.1 - 0.17 11.9 8.0 0.58 10.2 2.0 3.0 2 1 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 MS_channel PF00924.18 GAM43041.1 - 0.17 11.4 1.9 0.19 11.3 1.5 1.2 1 1 0 1 1 1 0 Mechanosensitive ion channel BST2 PF16716.5 GAM43041.1 - 0.18 12.4 26.5 0.11 13.1 7.7 3.6 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 KASH_CCD PF14662.6 GAM43041.1 - 0.2 11.4 30.0 0.83 9.5 13.2 2.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 GAM43041.1 - 0.23 11.5 14.5 0.32 11.0 4.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 GAM43041.1 - 0.36 10.9 35.4 0.21 11.6 10.2 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 GAM43041.1 - 0.37 11.2 24.3 3.7 8.0 24.5 1.9 1 1 0 1 1 1 0 Fez1 CENP-F_leu_zip PF10473.9 GAM43041.1 - 0.52 10.3 31.0 2.3 8.2 10.8 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CLZ PF16526.5 GAM43041.1 - 0.52 10.7 21.8 4.2 7.8 1.6 3.3 1 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Lebercilin PF15619.6 GAM43041.1 - 0.56 9.8 30.9 5.1 6.7 23.7 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease SlyX PF04102.12 GAM43041.1 - 0.59 10.8 22.2 4.8 7.9 3.2 3.8 1 1 2 3 3 3 0 SlyX Laminin_II PF06009.12 GAM43041.1 - 0.82 9.7 17.8 0.15 12.1 6.8 2.2 1 1 1 2 2 2 0 Laminin Domain II FPP PF05911.11 GAM43041.1 - 0.83 7.8 27.1 0.23 9.6 12.7 1.9 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil ZapB PF06005.12 GAM43041.1 - 1.3 9.6 37.4 5.5 7.5 0.7 3.8 1 1 1 2 2 1 0 Cell division protein ZapB Striatin PF08232.12 GAM43041.1 - 1.4 9.5 23.3 7.9 7.1 17.9 2.1 1 1 1 2 2 2 0 Striatin family DUF5595 PF18077.1 GAM43041.1 - 1.6 8.9 21.3 1.3 9.2 5.6 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF5595) HAP1_N PF04849.13 GAM43041.1 - 1.6 7.8 28.5 2.9 7.0 5.3 2.4 1 1 1 2 2 2 0 HAP1 N-terminal conserved region FAM76 PF16046.5 GAM43041.1 - 1.7 7.9 22.2 2.4 7.4 8.4 2.1 1 1 1 2 2 2 0 FAM76 protein DUF465 PF04325.13 GAM43041.1 - 1.8 8.7 15.9 2.4 8.3 0.1 4.2 3 1 1 4 4 3 0 Protein of unknown function (DUF465) Prefoldin_2 PF01920.20 GAM43041.1 - 2 8.4 31.7 1.2 9.1 1.2 4.0 2 1 0 2 2 1 0 Prefoldin subunit HMMR_N PF15905.5 GAM43041.1 - 2 7.8 31.1 8 5.8 31.1 1.7 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Fmp27_WPPW PF10359.9 GAM43041.1 - 2.3 7.0 23.0 0.11 11.3 9.0 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF3450 PF11932.8 GAM43041.1 - 2.4 7.4 28.3 4.8 6.4 1.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 GAM43041.1 - 2.7 8.1 35.0 1 9.4 12.0 3.4 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Phage_GPO PF05929.11 GAM43041.1 - 3 7.4 19.9 1.1 8.8 15.0 1.9 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase PRKG1_interact PF15898.5 GAM43041.1 - 3 8.8 27.7 6.8 7.7 20.0 2.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4201 PF13870.6 GAM43041.1 - 3.1 7.5 26.9 40 3.9 19.8 2.1 1 1 1 2 2 1 0 Domain of unknown function (DUF4201) XhlA PF10779.9 GAM43041.1 - 3.3 8.0 24.8 3 8.1 5.3 4.0 1 1 3 4 4 4 0 Haemolysin XhlA DUF1640 PF07798.11 GAM43041.1 - 3.9 7.5 24.2 1.6e+02 2.2 24.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) bZIP_2 PF07716.15 GAM43041.1 - 4.1 7.6 35.7 1.9 8.6 5.2 5.8 2 2 2 4 4 3 0 Basic region leucine zipper OmpH PF03938.14 GAM43041.1 - 4.3 7.7 32.2 4.3 7.7 18.4 2.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 GAM43041.1 - 4.7 6.7 16.2 6.8 6.2 16.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FlxA PF14282.6 GAM43041.1 - 5 7.2 25.5 8.4 6.5 0.2 3.1 1 1 2 3 3 3 0 FlxA-like protein DUF720 PF05302.11 GAM43041.1 - 5.5 6.9 9.2 1.1 9.1 5.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF720) Lectin_N PF03954.14 GAM43041.1 - 5.8 6.7 14.3 3 7.6 4.8 2.6 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF2730 PF10805.8 GAM43041.1 - 6 7.0 15.4 1.2 9.3 1.8 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) FapA PF03961.13 GAM43041.1 - 6.7 5.2 25.5 0.59 8.7 9.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A TMPIT PF07851.13 GAM43041.1 - 7.5 5.7 21.8 2.2 7.4 3.5 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF2203 PF09969.9 GAM43041.1 - 7.7 7.3 18.3 11 6.7 5.6 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) BRE1 PF08647.11 GAM43041.1 - 7.7 6.7 28.6 45 4.2 9.0 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase AAA_13 PF13166.6 GAM43041.1 - 8.4 4.9 23.1 17 3.9 23.1 1.5 1 1 0 1 1 1 0 AAA domain CENP-H PF05837.12 GAM43041.1 - 8.7 6.8 26.7 1.8e+04 -4.3 26.7 2.7 1 1 0 1 1 0 0 Centromere protein H (CENP-H) YabA PF06156.13 GAM43041.1 - 9.3 6.9 24.2 57 4.4 0.5 3.0 1 1 0 2 2 2 0 Initiation control protein YabA Rootletin PF15035.6 GAM43041.1 - 9.7 6.2 28.6 1e+02 2.8 28.4 2.2 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Nop25 PF09805.9 GAM43042.1 - 3.9e-39 134.3 14.0 3.9e-39 134.3 14.0 3.0 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) Serglycin PF04360.12 GAM43042.1 - 0.51 10.3 3.0 0.76 9.7 1.6 1.8 1 1 0 2 2 2 0 Serglycin ATP-synt_S1 PF05827.12 GAM43043.1 - 0.00029 20.7 0.5 0.0005 19.9 0.5 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) EXS PF03124.14 GAM43045.1 - 8.5e-108 360.6 11.7 9.6e-108 360.4 11.7 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.14 GAM43046.1 - 5.2e-43 147.2 3.3 7e-43 146.8 3.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 GAM43046.1 - 1e-11 44.5 8.5 1.2e-10 41.1 9.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM43046.1 - 1.9e-11 44.1 9.9 7.4e-11 42.2 10.4 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 GAM43046.1 - 1.3e-10 41.0 7.3 2.1e-10 40.3 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM43046.1 - 2.1e-10 40.4 4.7 3.5e-09 36.5 4.5 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAM43046.1 - 2.1e-10 40.3 7.1 3.6e-10 39.5 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM43046.1 - 8.3e-08 32.1 6.8 1.4e-07 31.3 6.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAM43046.1 - 1.2e-07 31.5 6.8 1.9e-07 30.8 6.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GAM43046.1 - 4e-06 27.0 8.7 1e-05 25.7 8.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 GAM43046.1 - 3.6e-05 23.8 8.8 3.6e-05 23.8 8.8 2.0 3 0 0 3 3 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GAM43046.1 - 0.0044 16.8 2.5 0.23 11.3 2.6 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 GAM43046.1 - 0.0055 16.8 7.1 0.01 16.0 7.1 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-Nse PF11789.8 GAM43046.1 - 0.0066 16.2 2.8 0.091 12.6 4.5 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 GAM43046.1 - 0.016 15.3 2.7 0.034 14.2 2.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.12 GAM43046.1 - 0.15 11.4 1.8 0.37 10.1 0.3 2.3 2 1 0 2 2 2 0 Rtf2 RING-finger zf-RING_4 PF14570.6 GAM43046.1 - 0.19 11.5 8.4 0.5 10.2 8.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 GAM43046.1 - 1.7 8.8 8.0 3 8.1 6.6 2.1 2 1 0 2 2 1 0 FYVE zinc finger zf-RING_11 PF17123.5 GAM43046.1 - 3.5 7.5 7.7 1.1 9.0 3.8 2.2 2 0 0 2 2 2 0 RING-like zinc finger IBR PF01485.21 GAM43046.1 - 5.3 7.3 8.6 21 5.5 8.6 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DNA_pol_A_exo1 PF01612.20 GAM43047.1 - 1.8e-16 60.4 0.0 2.2e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease YkyA PF10368.9 GAM43049.1 - 1.8 8.2 10.0 0.21 11.2 4.1 2.2 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein KxDL PF10241.9 GAM43049.1 - 4 7.8 11.7 0.31 11.4 3.8 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein LSM PF01423.22 GAM43050.1 - 1.4e-21 76.0 0.1 1.5e-21 75.8 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAM43050.1 - 0.0071 16.5 0.0 0.0085 16.2 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Glyco_hydro_18 PF00704.28 GAM43051.1 - 4.1e-48 164.7 0.6 8.1e-48 163.7 0.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 GAM43051.1 - 1.5e-05 25.0 0.0 0.0019 18.2 0.0 2.9 2 0 0 2 2 2 1 LysM domain Chitin_bind_1 PF00187.19 GAM43051.1 - 0.00019 21.8 10.0 0.00019 21.8 10.0 3.4 3 0 0 3 3 3 1 Chitin recognition protein RhoGAP PF00620.27 GAM43052.1 - 2e-16 60.2 0.2 4.6e-16 59.0 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 GAM43052.1 - 2.1e-11 43.7 0.0 4.6e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 GAM43052.1 - 9.8e-08 32.2 0.0 3.3e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain AA_permease PF00324.21 GAM43053.1 - 1.7e-151 505.1 43.7 1.9e-151 504.9 43.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAM43053.1 - 4.7e-38 131.1 44.6 5.6e-38 130.9 44.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 GAM43053.1 - 0.0011 17.9 0.5 0.0024 16.7 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4781) Peroxidase_2 PF01328.17 GAM43054.1 - 1.5e-45 156.0 0.0 2.3e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 CFEM PF05730.11 GAM43055.1 - 1.2e-16 60.6 9.8 2e-16 59.8 9.8 1.4 1 0 0 1 1 1 1 CFEM domain GMC_oxred_C PF05199.13 GAM43056.1 - 4e-28 98.7 0.0 7.9e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 GAM43056.1 - 5.3e-09 35.9 0.0 0.00043 19.8 0.0 3.1 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 GAM43056.1 - 0.00041 20.5 0.0 0.00097 19.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM43056.1 - 0.0037 16.5 0.0 0.0065 15.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM43056.1 - 0.039 13.0 0.8 0.076 12.1 0.8 1.4 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 GAM43056.1 - 0.12 12.1 0.3 0.24 11.0 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 GAM43056.1 - 0.16 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein adh_short PF00106.25 GAM43057.1 - 1e-18 67.5 0.2 1.5e-18 67.0 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 GAM43057.1 - 2.9e-06 26.9 0.2 5.9e-05 22.6 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAM43057.1 - 7.1e-05 22.8 0.2 0.0003 20.7 0.0 1.9 2 0 0 2 2 2 1 KR domain TrkA_N PF02254.18 GAM43057.1 - 0.049 13.9 0.1 0.22 11.8 0.0 2.0 2 1 1 3 3 3 0 TrkA-N domain eIF3m_C_helix PF18005.1 GAM43058.1 - 5.3e-10 38.8 3.0 1.2e-09 37.7 3.0 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 GAM43058.1 - 3.4e-09 37.2 0.0 7.5e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain DNA_pol_phi PF04931.13 GAM43058.1 - 0.0049 15.0 0.1 0.0067 14.6 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase phi TMA7 PF09072.10 GAM43058.1 - 1.8 9.4 4.7 0.63 10.9 0.9 2.1 2 0 0 2 2 2 0 Translation machinery associated TMA7 Med3 PF11593.8 GAM43059.1 - 5.7 6.0 17.0 7.4 5.7 17.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal 4HBT PF03061.22 GAM43060.1 - 1.9e-08 34.5 0.0 3.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 GAM43061.1 - 4.4e-49 168.0 0.4 5.1e-49 167.8 0.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 GAM43061.1 - 7.7e-06 26.2 0.0 0.089 13.2 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily Glyco_transf_20 PF00982.21 GAM43062.1 - 1.1e-163 545.3 0.0 1.6e-163 544.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAM43062.1 - 1.9e-39 135.1 0.0 3.2e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 GAM43062.1 - 0.087 12.5 0.3 0.15 11.7 0.3 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain Stk19 PF10494.9 GAM43063.1 - 7.8e-89 297.6 0.0 9.4e-89 297.3 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DUF3074 PF11274.8 GAM43064.1 - 3.4e-46 157.6 0.1 4.4e-46 157.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) zf-H2C2_2 PF13465.6 GAM43065.1 - 1.7e-11 43.9 19.5 7.1e-06 26.2 1.4 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 GAM43065.1 - 3.5e-09 36.6 25.0 0.0046 17.3 8.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 GAM43065.1 - 1.4e-06 28.2 18.8 0.0021 18.0 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 GAM43065.1 - 4.2e-06 27.1 21.3 0.044 14.6 6.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 GAM43065.1 - 0.0069 16.7 6.2 0.016 15.5 6.2 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 GAM43065.1 - 0.044 13.6 0.5 0.11 12.4 0.5 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif Zn-ribbon_8 PF09723.10 GAM43065.1 - 0.14 12.3 6.8 0.14 12.3 1.3 2.6 1 1 2 3 3 3 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 GAM43065.1 - 0.18 12.2 8.7 2 8.8 2.4 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.8 GAM43065.1 - 0.18 12.1 2.0 0.17 12.2 0.7 1.6 1 1 0 1 1 1 0 zinc-finger-containing domain DZR PF12773.7 GAM43065.1 - 0.22 11.6 6.5 1.7 8.8 5.8 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-CHCC PF10276.9 GAM43065.1 - 0.4 10.8 5.9 0.87 9.7 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger domain zf-C2HC_2 PF13913.6 GAM43065.1 - 0.57 10.1 5.5 0.31 11.0 0.5 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 GAM43065.1 - 0.72 9.7 3.2 1.9 8.4 0.3 2.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) HNH_5 PF14279.6 GAM43065.1 - 1.1 9.2 3.7 5.3 7.0 1.9 2.8 2 1 0 2 2 2 0 HNH endonuclease zinc_ribbon_15 PF17032.5 GAM43065.1 - 2.1 9.1 4.5 12 6.7 4.1 2.0 1 1 1 2 2 2 0 zinc-ribbon family GAGA PF09237.11 GAM43065.1 - 2.6 7.9 6.3 11 5.9 1.0 2.7 1 1 1 2 2 2 0 GAGA factor zf-C2H2_3rep PF18868.1 GAM43065.1 - 4.1 8.1 8.1 10 6.8 2.7 3.5 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 GAM43065.1 - 9.8 5.9 7.8 21 4.8 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF1706 PF08020.11 GAM43066.1 - 0.089 12.7 1.4 0.63 9.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) ADH_N PF08240.12 GAM43068.1 - 1.3e-25 89.4 0.1 2.2e-25 88.6 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM43068.1 - 8.8e-24 83.9 1.2 1.3e-23 83.4 1.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM43068.1 - 0.0013 19.7 0.0 0.0027 18.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 GAM43068.1 - 0.0021 17.9 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.21 GAM43068.1 - 0.11 11.8 1.1 0.16 11.2 1.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amidohydro_2 PF04909.14 GAM43069.1 - 2.3e-17 63.7 0.4 7.5e-17 62.0 0.4 1.9 1 1 0 1 1 1 1 Amidohydrolase AAA PF00004.29 GAM43070.1 - 7.4e-12 45.8 0.0 2e-11 44.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM43070.1 - 1.8e-10 41.4 0.4 2.1e-09 38.0 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAM43070.1 - 2.5e-09 37.5 0.0 6.4e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 GAM43070.1 - 4.9e-08 32.8 0.5 6.4e-07 29.3 0.1 3.1 3 1 0 3 3 3 1 CDC6, C terminal winged helix domain AAA_19 PF13245.6 GAM43070.1 - 0.00014 22.2 0.0 0.00034 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 GAM43070.1 - 0.00034 20.1 0.0 0.00077 18.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein AAA_lid_10 PF17872.1 GAM43070.1 - 0.0005 20.1 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA lid domain NACHT PF05729.12 GAM43070.1 - 0.0012 18.8 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 GAM43070.1 - 0.012 15.2 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 GAM43070.1 - 0.016 15.0 0.0 0.049 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 GAM43070.1 - 0.018 14.8 0.0 0.14 11.9 0.0 2.1 1 1 1 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 GAM43070.1 - 0.021 15.2 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 GAM43070.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 GAM43070.1 - 0.076 13.0 0.0 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 GAM43070.1 - 0.086 12.0 0.0 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SSE PF00437.20 GAM43070.1 - 0.089 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TIP49 PF06068.13 GAM43070.1 - 0.1 11.8 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 GAM43070.1 - 0.15 12.6 0.8 0.35 11.4 0.0 2.1 2 1 0 2 2 1 0 AAA domain Thioredoxin_7 PF13899.6 GAM43071.1 - 9.9e-18 64.1 0.0 2.1e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 GAM43071.1 - 3.9e-15 55.4 0.7 8e-15 54.4 0.7 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 GAM43071.1 - 3.1e-08 33.7 0.0 9.5e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.13 GAM43071.1 - 0.06 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 TAP C-terminal domain Thioredoxin_2 PF13098.6 GAM43071.1 - 0.063 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Pkinase PF00069.25 GAM43072.1 - 1.7e-50 171.9 0.0 4e-38 131.3 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM43072.1 - 1.2e-36 126.3 0.0 5e-27 94.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Fungal_trans PF04082.18 GAM43073.1 - 1.6e-20 73.2 0.0 2.9e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM43073.1 - 2.5e-06 27.5 11.9 4.4e-06 26.7 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_luciferase PF00296.20 GAM43073.1 - 0.15 11.4 0.1 0.46 9.9 0.0 1.7 2 0 0 2 2 2 0 Luciferase-like monooxygenase MR_MLE_C PF13378.6 GAM43074.1 - 6.3e-43 146.9 0.0 8.7e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 GAM43074.1 - 1.7e-10 41.1 0.0 2.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short_C2 PF13561.6 GAM43075.1 - 1.1e-45 156.0 0.1 1.3e-44 152.5 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM43075.1 - 5.1e-36 124.0 1.8 2.2e-35 121.9 1.8 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM43075.1 - 1.4e-06 28.4 0.5 2.3e-06 27.6 0.5 1.3 1 0 0 1 1 1 1 KR domain ADK PF00406.22 GAM43076.1 - 4.9e-42 143.6 0.0 6.4e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAM43076.1 - 1.1e-35 123.1 0.0 2e-35 122.2 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM43076.1 - 1.1e-09 38.9 0.0 4.7e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 GAM43076.1 - 4.5e-07 29.7 0.1 4e-05 23.4 0.1 2.2 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 GAM43076.1 - 3.9e-06 27.1 0.0 1.5e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAM43076.1 - 0.12 11.6 0.1 0.87 8.8 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin DUF202 PF02656.15 GAM43077.1 - 0.13 12.7 4.4 2.9 8.4 0.8 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Oxidored_q2 PF00420.24 GAM43077.1 - 0.18 11.4 0.7 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L ELO PF01151.18 GAM43077.1 - 0.24 10.9 4.4 6.4 6.2 0.8 2.2 1 1 1 2 2 2 0 GNS1/SUR4 family THEG4 PF15834.5 GAM43077.1 - 0.52 10.3 4.9 0.26 11.3 1.6 2.1 2 0 0 2 2 2 0 Testis highly expressed protein 4 Vma12 PF11712.8 GAM43077.1 - 0.95 9.5 2.8 31 4.6 2.7 2.5 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4271 PF14093.6 GAM43077.1 - 1.9 8.3 6.8 1.8 8.4 2.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) DUF1218 PF06749.12 GAM43077.1 - 8.1 7.0 6.8 0.31 11.6 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Cnd2 PF05786.14 GAM43078.1 - 0 1046.4 0.3 0 1046.2 0.3 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 GAM43078.1 - 0.0066 16.7 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal FXMRP1_C_core PF12235.8 GAM43078.1 - 0.11 13.1 0.3 0.11 13.1 0.3 2.8 3 0 0 3 3 3 0 Fragile X-related 1 protein core C terminal Na_Ca_ex PF01699.24 GAM43079.1 - 2.8e-46 157.2 33.0 1.1e-23 83.9 15.8 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein EF-hand_4 PF12763.7 GAM43080.1 - 2.1e-23 82.3 0.0 3.8e-13 49.3 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 GAM43080.1 - 2.3e-10 39.9 1.5 3.7e-10 39.3 0.2 2.1 2 0 0 2 2 2 1 WH2 motif DUF1720 PF08226.11 GAM43080.1 - 1.6e-09 38.0 53.4 8.6e-08 32.5 28.0 7.6 5 2 2 7 7 7 3 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 GAM43080.1 - 9.8e-05 21.6 0.0 0.002 17.5 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 GAM43080.1 - 0.0068 16.2 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 GAM43080.1 - 0.014 15.8 0.0 0.014 15.8 0.0 3.4 5 0 0 5 5 5 0 EF-hand domain pair EF-hand_6 PF13405.6 GAM43080.1 - 0.037 13.9 0.0 1.1 9.3 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain FAM176 PF14851.6 GAM43081.1 - 1.6 8.4 4.8 4.8 6.8 4.8 1.8 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 GAM43081.1 - 8.9 6.8 13.0 4.3 7.8 7.5 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.32 GAM43082.1 - 5.2e-17 61.9 7.1 2.8e-07 31.1 0.3 5.8 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM43082.1 - 4.2e-08 33.4 0.0 0.00087 19.5 0.0 3.8 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 GAM43082.1 - 0.00053 18.8 0.3 0.0032 16.3 0.1 1.9 1 1 1 2 2 2 1 Nup133 N terminal like WDCP PF15390.6 GAM43082.1 - 0.009 14.4 0.0 0.11 10.9 0.0 2.1 2 0 0 2 2 2 1 WD repeat and coiled-coil-containing protein family Coatomer_WDAD PF04053.14 GAM43082.1 - 0.018 14.1 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Frtz PF11768.8 GAM43082.1 - 0.03 12.6 0.1 0.15 10.4 0.0 1.8 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 GAM43082.1 - 0.032 12.7 0.0 12 4.3 0.1 3.0 2 2 1 3 3 3 0 Cytochrome D1 heme domain Utp8 PF10395.9 GAM43082.1 - 0.067 11.7 1.0 2.8 6.3 0.0 1.9 1 1 1 2 2 2 0 Utp8 family Mito_carr PF00153.27 GAM43083.1 - 8e-52 173.1 4.7 2.7e-18 65.6 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribonuc_red_sm PF00268.21 GAM43084.1 - 1.4e-122 408.6 0.6 1.7e-122 408.3 0.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SNF2_N PF00176.23 GAM43085.1 - 6.5e-69 232.3 0.0 9.1e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 GAM43085.1 - 2.8e-23 81.6 0.0 9.5e-23 80.0 0.0 1.9 2 0 0 2 2 2 1 HIRAN domain Helicase_C PF00271.31 GAM43085.1 - 1.8e-15 57.2 0.0 4.3e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM43085.1 - 7.2e-05 22.9 0.0 0.00016 21.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 GAM43085.1 - 0.00075 19.3 4.0 0.0015 18.3 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM43085.1 - 0.0014 18.6 7.8 0.0028 17.6 7.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger PLU-1 PF08429.11 GAM43085.1 - 0.0022 17.2 1.3 0.0048 16.1 1.3 1.5 1 0 0 1 1 1 1 PLU-1-like protein zf-C3HC4 PF00097.25 GAM43085.1 - 0.0022 17.8 7.4 0.0042 16.9 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM43085.1 - 0.0029 17.4 6.3 0.005 16.7 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM43085.1 - 0.0049 17.2 7.8 0.011 16.0 7.8 1.7 1 0 0 1 1 1 1 Ring finger domain UBA_4 PF14555.6 GAM43085.1 - 0.084 12.7 0.1 0.42 10.5 0.0 2.2 3 0 0 3 3 3 0 UBA-like domain zf-RING_5 PF14634.6 GAM43085.1 - 0.11 12.5 6.2 0.24 11.4 6.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAM43085.1 - 0.5 10.6 7.0 1 9.6 7.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SQS_PSY PF00494.19 GAM43086.1 - 1.6e-50 172.1 0.0 2.6e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase CorA PF01544.18 GAM43087.1 - 6.3e-25 88.1 10.5 1.4e-18 67.2 1.4 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein DNApol_Exo PF18136.1 GAM43088.1 - 2.1e-105 351.9 0.1 3.9e-105 351.0 0.1 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 GAM43088.1 - 2.7e-56 191.2 0.0 4.5e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 GAM43088.1 - 0.03 14.0 0.3 0.66 9.7 0.3 2.4 1 1 0 1 1 1 0 3'-5' exonuclease Bromodomain PF00439.25 GAM43088.1 - 0.059 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Bromodomain zf-RING_UBOX PF13445.6 GAM43089.1 - 3.1e-09 36.7 0.3 6.2e-09 35.7 0.2 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAM43089.1 - 5.3e-09 35.8 8.0 9.3e-09 35.0 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM43089.1 - 1.2e-08 34.6 4.6 1.2e-08 34.6 4.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM43089.1 - 1.5e-07 31.6 6.9 2.9e-07 30.7 6.9 1.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAM43089.1 - 1.6e-07 31.1 9.3 4.1e-07 29.8 9.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM43089.1 - 1e-06 28.6 7.3 1.7e-06 27.9 7.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAM43089.1 - 3.6e-05 23.8 3.8 0.0006 19.9 4.7 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAM43089.1 - 9.2e-05 22.2 7.6 0.0016 18.3 7.6 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-4CXXC_R1 PF10497.9 GAM43089.1 - 0.00089 19.4 2.0 0.0014 18.8 2.0 1.3 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 SART-1 PF03343.13 GAM43089.1 - 0.046 12.3 0.1 0.044 12.4 0.1 1.1 1 0 0 1 1 1 0 SART-1 family zf-RING_11 PF17123.5 GAM43089.1 - 0.28 11.0 6.9 0.69 9.7 6.9 1.7 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 GAM43089.1 - 0.29 11.0 9.3 0.94 9.3 9.3 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 GAM43089.1 - 0.91 9.9 8.1 3.1 8.1 8.1 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain FYVE PF01363.21 GAM43089.1 - 1 9.6 5.8 2.7 8.2 5.8 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_10 PF16685.5 GAM43089.1 - 1.1 9.4 6.5 7.8 6.7 6.6 2.2 1 1 1 2 2 2 0 zinc RING finger of MSL2 Gin PF10764.9 GAM43089.1 - 4.8 7.2 6.7 3 7.9 4.1 1.9 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin UPF0052 PF01933.18 GAM43090.1 - 5.6e-60 203.1 0.0 7.6e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 ThiJ_like PF17124.5 GAM43091.1 - 1.6e-54 184.6 0.0 1.9e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 GAM43091.1 - 2.8e-10 40.2 0.0 6e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 GAM43091.1 - 0.0092 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ArabFuran-catal PF09206.11 GAM43092.1 - 3.7e-143 476.6 11.9 4.8e-143 476.2 11.9 1.1 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 GAM43092.1 - 4.1e-57 192.1 2.1 6.5e-57 191.5 2.1 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain IL33 PF15095.6 GAM43092.1 - 0.0022 17.5 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Interleukin 33 TRI12 PF06609.13 GAM43093.1 - 6.2e-52 176.8 17.6 8.1e-52 176.5 17.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 GAM43093.1 - 1.2e-26 93.4 51.6 1.3e-25 90.1 49.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM43093.1 - 2.1e-10 40.1 9.5 2.1e-10 40.1 9.5 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter CrgA PF06781.12 GAM43093.1 - 2.3 8.3 7.2 0.73 9.9 0.2 3.4 2 1 0 2 2 2 0 Cell division protein CrgA Lactamase_B PF00753.27 GAM43095.1 - 1.5e-06 28.4 0.7 3.4e-06 27.2 0.7 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM43095.1 - 0.035 13.6 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain FAA_hydrolase PF01557.18 GAM43096.1 - 7.2e-48 163.1 0.0 9.6e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 GAM43096.1 - 3.9e-23 81.7 0.0 5.9e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal AMP-binding PF00501.28 GAM43097.1 - 3.6e-45 154.3 0.0 5.4e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Putative_PNPOx PF01243.20 GAM43097.1 - 1.9e-07 31.2 0.0 3e-06 27.3 0.0 2.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ACAS_N PF16177.5 GAM43097.1 - 0.042 13.8 0.1 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus EamA PF00892.20 GAM43097.1 - 0.079 13.1 19.4 0.024 14.8 14.0 2.6 2 1 0 2 2 2 0 EamA-like transporter family TMEM234 PF10639.9 GAM43097.1 - 0.14 12.2 2.0 0.33 11.0 2.0 1.6 1 0 0 1 1 1 0 Putative transmembrane family 234 Hormone_3 PF00159.18 GAM43097.1 - 0.2 11.8 1.6 0.46 10.6 0.3 2.4 2 0 0 2 2 2 0 Pancreatic hormone peptide Voltage_CLC PF00654.20 GAM43098.1 - 6.3e-87 292.1 26.9 6.3e-87 292.1 26.9 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 GAM43098.1 - 4.7e-12 46.2 0.0 3.1e-05 24.3 0.0 2.7 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.23 GAM43099.1 - 7.1e-16 58.2 0.4 3.7e-15 56.0 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAM43099.1 - 0.0024 18.2 0.2 0.0048 17.2 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 UCR_TM PF02921.14 GAM43100.1 - 3.8e-11 43.3 0.6 7.9e-11 42.3 0.6 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 GAM43100.1 - 5e-11 42.4 0.0 9.9e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PPR_2 PF13041.6 GAM43101.1 - 1.1e-43 147.1 11.0 2e-09 37.5 0.0 12.5 10 4 4 14 14 14 7 PPR repeat family PPR_3 PF13812.6 GAM43101.1 - 1.3e-28 98.8 0.3 0.0036 17.3 0.0 10.6 8 4 3 11 11 11 8 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAM43101.1 - 7.6e-23 79.9 0.0 2.4e-06 27.2 0.0 10.5 10 0 0 10 10 10 3 PPR repeat PPR PF01535.20 GAM43101.1 - 6e-21 73.2 34.6 0.00056 20.0 0.1 15.6 21 2 0 21 21 21 6 PPR repeat PPR_long PF17177.4 GAM43101.1 - 1.8e-19 70.0 17.6 1.4e-08 34.4 0.1 6.3 5 1 1 6 6 6 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 GAM43101.1 - 5.8e-09 36.4 0.0 7.5e-07 29.6 0.0 4.0 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) RPN7 PF10602.9 GAM43101.1 - 0.015 15.0 0.2 3.6 7.3 0.0 3.5 3 0 0 3 3 3 0 26S proteasome subunit RPN7 Serglycin PF04360.12 GAM43101.1 - 0.019 14.9 0.9 0.054 13.4 0.9 1.8 1 0 0 1 1 1 0 Serglycin SelB-wing_2 PF09106.11 GAM43101.1 - 0.021 15.0 0.0 0.47 10.7 0.0 3.6 2 0 0 2 2 2 0 Elongation factor SelB, winged helix TPR_7 PF13176.6 GAM43101.1 - 0.033 14.2 1.7 16 5.8 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4205 PF13898.6 GAM43101.1 - 0.1 11.5 0.6 0.22 10.4 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) DUF507 PF04368.13 GAM43101.1 - 0.2 11.6 2.1 4 7.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF507) GHMP_kinases_N PF00288.26 GAM43102.1 - 9.8e-14 51.3 1.4 2e-13 50.3 1.4 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAM43102.1 - 1e-10 41.8 0.6 3.3e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal Rad60-SLD_2 PF13881.6 GAM43103.1 - 1.1e-11 44.8 0.0 3.5e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAM43103.1 - 0.00059 20.4 0.0 0.0017 18.9 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 GAM43103.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family UMP1 PF05348.11 GAM43104.1 - 1.6e-37 128.3 0.0 2.1e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Ribosom_S12_S23 PF00164.25 GAM43105.1 - 1.4e-29 102.0 0.9 1.4e-29 102.0 0.9 1.6 2 0 0 2 2 2 1 Ribosomal protein S12/S23 TPR_2 PF07719.17 GAM43106.1 - 4.6e-16 57.6 9.2 0.36 11.1 0.0 10.4 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAM43106.1 - 3e-14 53.0 3.0 0.00025 21.3 0.2 7.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM43106.1 - 5.7e-14 51.0 7.3 0.05 13.6 0.0 9.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAM43106.1 - 1.9e-13 50.0 5.7 0.9 10.5 0.0 9.5 8 2 2 10 10 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM43106.1 - 4.7e-13 49.4 0.1 0.0026 18.2 0.0 6.7 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM43106.1 - 2.7e-12 45.9 7.8 0.17 11.8 0.0 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM43106.1 - 3e-10 39.5 3.9 0.066 13.5 0.0 7.4 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM43106.1 - 7.8e-10 39.2 0.0 2.3 8.9 0.0 6.6 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM43106.1 - 2.2e-09 36.8 9.2 0.15 11.8 0.1 8.7 9 1 1 10 10 10 2 TPR repeat TPR_6 PF13174.6 GAM43106.1 - 9.2e-09 35.4 13.3 8.4 7.3 0.0 9.7 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_15 PF13429.6 GAM43106.1 - 2.9e-07 30.0 0.1 0.92 8.7 0.2 4.5 2 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM43106.1 - 5.7e-07 29.7 0.3 2.5 8.4 0.0 5.1 1 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 GAM43106.1 - 3.9e-05 23.2 0.3 0.38 10.1 0.0 3.0 2 0 0 2 2 2 2 MalT-like TPR region NACHT PF05729.12 GAM43106.1 - 5.3e-05 23.2 0.0 0.00033 20.6 0.0 2.3 2 0 0 2 2 2 1 NACHT domain RPN7 PF10602.9 GAM43106.1 - 5.9e-05 22.8 9.4 2.4 7.8 0.2 5.6 3 2 3 7 7 6 3 26S proteasome subunit RPN7 TPR_4 PF07721.14 GAM43106.1 - 0.00015 22.0 0.1 4.7 8.1 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM43106.1 - 0.00023 20.9 2.8 2.7 8.0 0.0 4.9 6 0 0 6 6 5 2 Tetratricopeptide repeat AAA_16 PF13191.6 GAM43106.1 - 0.0039 17.6 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain TPR_17 PF13431.6 GAM43106.1 - 0.0044 17.3 1.2 27 5.4 0.0 5.6 7 0 0 7 7 5 0 Tetratricopeptide repeat PPR PF01535.20 GAM43106.1 - 0.014 15.6 1.0 3 8.3 0.0 4.2 4 0 0 4 4 4 0 PPR repeat AAA_22 PF13401.6 GAM43106.1 - 0.017 15.4 0.0 0.076 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Asp_Glu_race_2 PF14669.6 GAM43106.1 - 0.085 12.5 0.1 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Putative aspartate racemase NARP1 PF12569.8 GAM43106.1 - 0.095 11.6 0.2 0.78 8.6 0.1 2.4 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 bZIP_1 PF00170.21 GAM43107.1 - 2.6e-07 30.6 12.3 9.1e-06 25.7 11.3 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAM43107.1 - 5.6e-06 26.3 16.6 1.8e-05 24.7 12.4 2.2 1 1 1 2 2 2 1 Basic region leucine zipper Laminin_I PF06008.14 GAM43107.1 - 0.0021 17.8 0.5 0.0024 17.6 0.5 1.0 1 0 0 1 1 1 1 Laminin Domain I HALZ PF02183.18 GAM43107.1 - 0.003 17.8 0.1 0.0071 16.5 0.0 1.7 1 1 1 2 2 2 1 Homeobox associated leucine zipper YabA PF06156.13 GAM43107.1 - 0.0055 17.3 0.8 0.0074 16.9 0.4 1.4 1 1 0 1 1 1 1 Initiation control protein YabA bZIP_Maf PF03131.17 GAM43107.1 - 0.0067 16.9 11.6 0.0067 16.9 11.6 1.7 1 1 1 2 2 2 1 bZIP Maf transcription factor PEPcase_2 PF14010.6 GAM43107.1 - 0.021 13.3 0.1 0.027 13.0 0.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Carboxyl_trans PF01039.22 GAM43107.1 - 0.066 11.8 0.5 0.082 11.5 0.5 1.0 1 0 0 1 1 1 0 Carboxyl transferase domain SpecificRecomb PF10136.9 GAM43107.1 - 0.42 8.8 2.4 0.51 8.6 2.4 1.0 1 0 0 1 1 1 0 Site-specific recombinase Aldolase_II PF00596.21 GAM43108.1 - 5.1e-37 127.6 0.0 6.9e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Flavoprotein PF02441.19 GAM43109.1 - 7.4e-22 77.8 0.0 9.1e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein UbiD PF01977.16 GAM43111.1 - 2.4e-115 385.6 0.0 2.8e-115 385.5 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DUF4440 PF14534.6 GAM43112.1 - 0.027 14.8 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF3723 PF12520.8 GAM43114.1 - 2e-52 178.6 0.0 2.5e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) p450 PF00067.22 GAM43117.1 - 1e-24 87.2 0.0 1.3e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2841 PF11001.8 GAM43118.1 - 1.8e-41 141.1 0.0 2.3e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF3723 PF12520.8 GAM43119.1 - 1.2e-57 195.8 0.7 1.2e-57 195.8 0.7 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3723) FAD_binding_3 PF01494.19 GAM43120.1 - 6.4e-07 28.9 0.0 1.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 GAM43120.1 - 1.2e-06 27.8 31.2 4.1e-06 26.0 31.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAM43120.1 - 0.00041 20.1 5.9 0.00041 20.1 5.9 2.6 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 Condensation PF00668.20 GAM43121.1 - 1.5e-05 23.9 0.0 0.00012 20.9 0.0 1.9 1 1 1 2 2 2 2 Condensation domain CPBP PF02517.16 GAM43122.1 - 0.45 10.9 4.0 1.2 9.6 4.0 1.7 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease MFS_1 PF07690.16 GAM43123.1 - 6.4e-23 81.2 49.4 3.2e-20 72.4 30.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4405 PF14358.6 GAM43123.1 - 0.77 10.3 9.0 0.16 12.5 3.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) TauD PF02668.16 GAM43124.1 - 2.2e-45 155.5 0.9 2.9e-45 155.2 0.9 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cu_amine_oxid PF01179.20 GAM43125.1 - 1.1e-123 413.2 3.4 1.1e-123 413.2 3.4 1.4 2 0 0 2 2 2 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 GAM43125.1 - 6.1e-32 109.2 0.2 1.9e-31 107.6 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 GAM43125.1 - 6.5e-08 32.7 0.0 1.3e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Glyco_hydro_cc PF11790.8 GAM43126.1 - 1.2e-40 139.6 0.1 1.3e-40 139.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Neurokinin_B PF03823.14 GAM43126.1 - 0.26 11.4 0.2 1.3 9.2 0.0 1.9 2 0 0 2 2 2 0 Neurokinin B Sugar_tr PF00083.24 GAM43127.1 - 1.8e-47 162.3 15.6 5.4e-27 94.7 5.7 2.8 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM43127.1 - 7.8e-15 54.6 21.3 7.8e-10 38.2 5.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily SET PF00856.28 GAM43129.1 - 0.0075 16.7 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 SET domain Fungal_trans PF04082.18 GAM43130.1 - 5.9e-19 68.1 0.0 1.1e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_31 PF01055.26 GAM43131.1 - 2.3e-114 383.0 1.8 3.5e-114 382.4 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GAM43131.1 - 1.6e-05 25.1 0.2 0.00011 22.5 0.0 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF4968 PF16338.5 GAM43131.1 - 0.0005 20.3 0.0 0.00084 19.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) DUF1349 PF07081.11 GAM43132.1 - 0.043 13.5 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1349) DUF5125 PF17163.4 GAM43132.1 - 0.047 13.9 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5125) Alpha_adaptinC2 PF02883.20 GAM43132.1 - 0.082 13.2 0.2 0.19 12.1 0.2 1.6 1 0 0 1 1 1 0 Adaptin C-terminal domain Sugar_tr PF00083.24 GAM43133.1 - 4.2e-88 296.2 21.7 5.2e-88 295.9 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM43133.1 - 2.2e-25 89.3 28.0 3e-25 88.9 28.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_5 PF05631.14 GAM43133.1 - 0.0011 18.0 0.9 0.0011 18.0 0.9 1.6 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 GAM43133.1 - 0.0015 17.5 20.8 0.012 14.5 12.7 2.3 2 0 0 2 2 2 2 MFS_1 like family TPR_19 PF14559.6 GAM43133.1 - 0.16 12.5 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Melibiase PF02065.18 GAM43134.1 - 1.5e-20 73.5 0.0 1.3e-14 53.9 0.0 2.1 1 1 1 2 2 2 2 Melibiase Glyoxalase_6 PF18029.1 GAM43134.1 - 0.025 15.4 0.1 0.067 14.0 0.1 1.7 2 0 0 2 2 2 0 Glyoxalase-like domain MFS_1 PF07690.16 GAM43135.1 - 2.4e-25 89.2 32.8 2.4e-25 89.2 32.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Neurensin PF14927.6 GAM43135.1 - 3.2 7.5 9.8 0.069 12.9 0.6 2.8 4 0 0 4 4 4 0 Neurensin DUF2207 PF09972.9 GAM43137.1 - 0.011 14.6 0.0 0.011 14.6 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SR-25 PF10500.9 GAM43137.1 - 6.3 6.3 19.7 12 5.4 19.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MFS_1 PF07690.16 GAM43138.1 - 8.1e-31 107.2 50.8 4.5e-26 91.6 32.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM43138.1 - 1.2e-18 67.2 24.9 4.7e-18 65.3 24.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Phage_cap_E PF03864.15 GAM43138.1 - 0.13 11.5 0.1 0.19 10.9 0.1 1.1 1 0 0 1 1 1 0 Phage major capsid protein E Cyclin PF08613.11 GAM43140.1 - 1.6e-39 135.8 2.3 2.6e-24 86.4 0.6 2.4 2 0 0 2 2 2 2 Cyclin Proteasome PF00227.26 GAM43141.1 - 1.1e-48 165.2 0.3 1.3e-48 165.0 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Hydrolase_4 PF12146.8 GAM43142.1 - 4.9e-15 55.4 0.0 4.5e-11 42.5 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM43142.1 - 1.3e-13 51.2 0.0 1.8e-09 37.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM43142.1 - 2.8e-06 28.1 0.0 2.9e-05 24.8 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 GAM43142.1 - 1e-05 24.4 0.0 0.017 13.8 0.1 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 GAM43142.1 - 1.7e-05 24.6 0.0 6.3e-05 22.7 0.0 1.9 2 1 0 2 2 2 1 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 GAM43142.1 - 0.00014 21.5 0.0 0.0046 16.6 0.0 2.1 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase DUF818 PF05677.12 GAM43142.1 - 0.00042 19.4 0.0 0.00055 19.0 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.11 GAM43142.1 - 0.00049 20.1 0.0 0.091 12.7 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 GAM43142.1 - 0.00067 19.3 0.0 0.012 15.2 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAM43142.1 - 0.0026 17.3 0.0 0.024 14.1 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 GAM43142.1 - 0.0033 17.3 0.0 0.0066 16.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 GAM43142.1 - 0.0064 16.2 0.0 0.032 13.9 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 GAM43142.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 GAM43142.1 - 0.029 14.2 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S28 PF05577.12 GAM43142.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_5 PF12695.7 GAM43142.1 - 0.14 12.0 0.0 0.67 9.7 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2974 PF11187.8 GAM43142.1 - 0.19 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) ATP11 PF06644.11 GAM43143.1 - 2.1e-102 342.6 0.0 2.4e-102 342.4 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein CCDC24 PF15669.5 GAM43143.1 - 0.0072 16.2 5.0 0.012 15.5 5.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family Myb_DNA-bind_6 PF13921.6 GAM43143.1 - 0.018 15.3 0.2 0.039 14.2 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain FAM60A PF15396.6 GAM43143.1 - 0.036 14.1 2.3 0.051 13.6 2.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A FAM199X PF15814.5 GAM43143.1 - 1 8.3 6.2 1.6 7.7 6.2 1.2 1 0 0 1 1 1 0 Protein family FAM199X FSA_C PF10479.9 GAM43143.1 - 1.7 6.7 4.6 2.5 6.1 4.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Herpes_pp85 PF04637.12 GAM43143.1 - 2.4 6.5 4.9 3.3 6.0 4.9 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Mannosidase_ig PF17786.1 GAM43144.1 - 7.8e-18 64.9 0.0 2.5e-17 63.2 0.0 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 GAM43144.1 - 9.2e-11 42.4 0.2 2.9e-10 40.8 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 LPMO_10 PF03067.15 GAM43145.1 - 2.3e-05 25.1 0.2 5.2e-05 24.0 0.2 1.6 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading RTA1 PF04479.13 GAM43146.1 - 6.7e-47 159.8 6.6 1.1e-46 159.1 6.6 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF805 PF05656.14 GAM43146.1 - 2.9 8.3 13.3 1.2 9.6 1.2 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF805) Aldo_ket_red PF00248.21 GAM43147.1 - 1.1e-68 231.6 0.0 1.3e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fumerase PF05681.14 GAM43147.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Aminotran_4 PF01063.19 GAM43148.1 - 2.7e-30 105.9 0.0 3.4e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Evr1_Alr PF04777.13 GAM43149.1 - 1.4e-26 92.8 0.1 2.5e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC4 PF18775.1 GAM43149.1 - 0.023 14.8 0.1 0.043 14.0 0.1 1.5 1 0 0 1 1 1 0 APOBEC4 RSF PF14876.6 GAM43150.1 - 0.011 14.7 0.1 0.018 14.0 0.1 1.3 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator Phage_TAC_1 PF06222.11 GAM43151.1 - 0.15 11.8 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone MFS_1 PF07690.16 GAM43152.1 - 3.5e-40 138.0 43.2 3.5e-40 138.0 43.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily PIRT PF15099.6 GAM43152.1 - 0.46 10.1 8.9 7.5 6.2 0.2 3.5 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family Glyco_hydro_92 PF07971.12 GAM43153.1 - 4.3e-145 484.2 1.8 5.5e-145 483.8 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 GAM43153.1 - 1.7e-57 195.1 0.5 2.7e-57 194.4 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain R3H PF01424.22 GAM43154.1 - 1.2e-12 47.6 0.0 2.9e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 R3H domain DUF1929 PF09118.11 GAM43155.1 - 1.9e-20 72.9 0.4 4e-20 71.9 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 GAM43155.1 - 1.8e-15 56.5 3.6 8e-08 32.3 0.0 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 GAM43155.1 - 3.7e-12 45.6 0.1 4e-05 23.1 0.1 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 GAM43155.1 - 7e-10 38.8 3.0 0.00076 19.4 0.0 4.7 4 1 0 4 4 4 2 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 GAM43155.1 - 1.8e-07 30.6 0.0 0.033 13.4 0.0 2.9 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.15 GAM43155.1 - 0.00018 21.3 7.5 0.18 11.8 0.1 4.8 4 2 0 4 4 4 2 Kelch motif FAD_binding_4 PF01565.23 GAM43155.1 - 0.001 18.8 1.0 0.04 13.6 0.1 2.6 2 1 0 2 2 2 1 FAD binding domain Kelch_3 PF13415.6 GAM43155.1 - 0.0059 16.9 0.2 0.17 12.2 0.0 3.5 3 1 0 3 3 3 1 Galactose oxidase, central domain DUF5122 PF17164.4 GAM43155.1 - 3.3 8.1 5.9 22 5.4 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Promethin PF16015.5 GAM43156.1 - 4.5e-14 52.3 7.7 7e-14 51.6 7.7 1.3 1 0 0 1 1 1 1 Promethin DUF3784 PF12650.7 GAM43156.1 - 0.038 14.2 1.5 0.038 14.2 1.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) DUF2207 PF09972.9 GAM43156.1 - 0.09 11.5 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2721 PF11026.8 GAM43156.1 - 1.5 8.7 7.1 18 5.2 7.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) Raffinose_syn PF05691.12 GAM43158.1 - 1e-50 172.4 2.2 1.6e-48 165.1 2.2 2.3 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 ADH_N PF08240.12 GAM43159.1 - 2.1e-29 101.6 1.7 3.9e-29 100.7 1.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM43159.1 - 6.2e-12 45.6 0.0 1.5e-06 28.2 0.0 2.7 2 1 1 3 3 3 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAM43159.1 - 0.0011 18.4 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N_assoc PF13823.6 GAM43159.1 - 0.0081 16.1 0.9 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 GAM43159.1 - 0.034 13.4 0.1 0.068 12.5 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SGL PF08450.12 GAM43160.1 - 8.3e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 GAM43160.1 - 0.0018 18.2 0.3 0.25 11.5 0.0 2.9 2 0 0 2 2 2 1 NHL repeat Lactonase PF10282.9 GAM43160.1 - 0.037 13.3 0.0 1.6 7.9 0.0 2.2 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller SBBP PF06739.11 GAM43160.1 - 0.047 13.7 0.2 6.9 6.8 0.0 2.6 2 0 0 2 2 2 0 Beta-propeller repeat MmgE_PrpD PF03972.14 GAM43161.1 - 3.7e-89 299.3 0.1 4.5e-89 299.0 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Mito_carr PF00153.27 GAM43162.1 - 4.1e-31 106.8 8.6 2.5e-14 53.0 0.2 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAM43162.1 - 0.0043 16.3 4.5 1.5 7.9 0.1 3.0 2 1 0 2 2 2 2 Gammaproteobacterial serine protease Lactamase_B PF00753.27 GAM43163.1 - 4.2e-08 33.4 1.0 6.4e-08 32.8 1.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM43163.1 - 0.03 13.8 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain SUA5 PF03481.13 GAM43163.1 - 0.035 14.7 0.0 0.055 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding TauD PF02668.16 GAM43164.1 - 2e-43 149.1 0.1 2.5e-43 148.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 GAM43165.1 - 5.9e-33 114.3 31.6 5.9e-33 114.3 31.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1269 PF06897.12 GAM43165.1 - 0.89 9.9 3.0 18 5.7 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) ResB PF05140.14 GAM43166.1 - 0.051 12.3 0.2 0.067 11.9 0.2 1.1 1 0 0 1 1 1 0 ResB-like family HgmA PF04209.13 GAM43167.1 - 8.7e-192 637.5 0.1 9.9e-192 637.3 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase p450 PF00067.22 GAM43168.1 - 2e-53 181.8 0.0 2.8e-52 178.0 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 FAA_hydrolase PF01557.18 GAM43168.1 - 2.2e-50 171.3 0.0 3.5e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 GAM43168.1 - 1.9e-30 105.2 0.0 3.6e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal TRI12 PF06609.13 GAM43169.1 - 9.7e-12 44.1 21.5 2.2e-07 29.7 21.5 3.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 GAM43169.1 - 0.0014 17.6 44.7 0.11 11.4 19.5 3.3 2 2 0 2 2 2 2 Major Facilitator Superfamily Tmemb_14 PF03647.13 GAM43169.1 - 2.7 8.8 17.7 0.19 12.5 1.6 3.6 4 1 0 4 4 4 0 Transmembrane proteins 14C Peptidase_S15 PF02129.18 GAM43170.1 - 9.4e-25 87.7 0.5 6.2e-23 81.8 0.5 2.5 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DSS1_SEM1 PF05160.13 GAM43170.1 - 0.068 13.2 0.1 8.3 6.6 0.0 2.6 2 0 0 2 2 2 0 DSS1/SEM1 family LigD_N PF13298.6 GAM43171.1 - 2.5e-37 127.4 0.1 4.9e-37 126.4 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) FAD_binding_4 PF01565.23 GAM43172.1 - 3.7e-27 94.7 1.7 5.8e-27 94.1 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM43172.1 - 8.4e-10 38.6 0.0 1.8e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like COQ7 PF03232.13 GAM43173.1 - 2.3e-67 226.1 1.1 2.9e-67 225.8 1.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 GAM43173.1 - 0.0013 19.1 0.2 0.0045 17.4 0.0 1.9 1 1 1 2 2 2 1 Rubrerythrin DUF2986 PF11661.8 GAM43173.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) Plus-3 PF03126.18 GAM43174.1 - 6.5e-33 113.5 0.0 8.1e-32 110.0 0.0 2.5 2 0 0 2 2 2 1 Plus-3 domain MRC1 PF09444.10 GAM43175.1 - 2.9e-41 141.4 23.8 2.9e-41 141.4 23.8 7.4 6 1 1 7 7 7 1 MRC1-like domain RibD_C PF01872.17 GAM43176.1 - 2.7e-29 102.4 0.0 4.5e-15 56.0 0.0 2.1 1 1 1 2 2 2 2 RibD C-terminal domain ZnuA PF01297.17 GAM43176.1 - 0.079 12.4 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic MA-Mit PF09245.10 GAM43176.1 - 0.12 11.8 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen HMGL-like PF00682.19 GAM43176.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 HMGL-like MFS_1 PF07690.16 GAM43177.1 - 2.7e-45 154.8 43.1 2.7e-45 154.8 43.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM43177.1 - 1.8e-15 56.8 13.9 1.8e-15 56.8 13.9 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter adh_short PF00106.25 GAM43178.1 - 2e-28 99.2 0.0 5.4e-28 97.8 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43178.1 - 5.3e-15 55.6 0.0 8.5e-15 54.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM43178.1 - 3.8e-10 40.0 0.2 5e-10 39.6 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM43178.1 - 3.1e-05 23.6 0.0 3.6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM43178.1 - 0.0077 15.7 0.0 0.0098 15.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAM43178.1 - 0.086 12.0 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ketoacyl-synt PF00109.26 GAM43179.1 - 9.8e-73 244.8 0.0 2.5e-72 243.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 GAM43179.1 - 1.3e-49 169.1 0.0 7.8e-49 166.6 0.0 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 GAM43179.1 - 1.7e-41 142.8 0.1 3e-41 142.0 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM43179.1 - 1.7e-34 118.3 0.5 4.2e-34 117.1 0.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 GAM43179.1 - 1.9e-11 43.7 0.0 8.4e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 GAM43179.1 - 5.5e-10 39.7 0.0 1.3e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 GAM43179.1 - 7.7e-10 39.0 0.2 2.2e-09 37.5 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 GAM43179.1 - 1e-06 28.4 0.3 2.2e-06 27.2 0.3 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lactamase_B PF00753.27 GAM43180.1 - 6.9e-12 45.8 3.3 1.1e-10 41.8 3.3 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM43180.1 - 0.003 17.1 1.1 0.0046 16.5 1.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain NAD_binding_10 PF13460.6 GAM43181.1 - 4.9e-16 59.1 0.0 6.8e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM43181.1 - 2.4e-06 27.3 0.0 4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 GAM43181.1 - 0.00012 21.2 0.6 0.00016 20.8 0.6 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 GAM43181.1 - 0.02 15.3 0.0 0.15 12.5 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 GAM43181.1 - 0.089 12.2 0.1 0.17 11.4 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM43181.1 - 0.11 11.6 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GMC_oxred_N PF00732.19 GAM43182.1 - 2.5e-50 171.6 0.0 1.9e-49 168.6 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM43182.1 - 1.7e-31 109.7 0.0 3e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAM43182.1 - 0.00012 21.3 0.0 0.00023 20.3 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAM43182.1 - 0.00064 19.9 0.0 0.0024 18.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM43182.1 - 0.00084 18.7 0.0 0.018 14.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM43182.1 - 0.0058 16.3 0.1 0.04 13.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAM43182.1 - 0.03 13.6 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 GAM43182.1 - 0.034 12.9 0.0 0.095 11.4 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 GAM43182.1 - 0.037 13.3 0.1 3.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Questin_oxidase PF14027.6 GAM43183.1 - 5.4e-84 282.7 0.1 6.6e-84 282.4 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like NAD_binding_10 PF13460.6 GAM43184.1 - 5.5e-14 52.5 0.0 1.3e-13 51.2 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM43184.1 - 1.8e-07 31.0 0.0 3.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAM43184.1 - 0.0084 15.6 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM43184.1 - 0.02 13.9 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 GAM43184.1 - 0.029 14.8 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 GAM43184.1 - 0.063 12.4 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAM43184.1 - 0.079 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase p450 PF00067.22 GAM43185.1 - 2.9e-56 191.2 0.0 3.7e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 GAM43186.1 - 3.3e-57 193.7 1.6 4.4e-57 193.3 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM43186.1 - 4.4e-49 166.6 2.4 5.4e-49 166.3 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM43186.1 - 5.9e-12 45.9 0.2 7.9e-12 45.4 0.2 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAM43186.1 - 0.018 14.3 0.3 0.57 9.5 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF460 PF04312.13 GAM43186.1 - 0.045 13.5 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF460) DUF1776 PF08643.10 GAM43186.1 - 0.097 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MCC-bdg_PDZ PF10506.9 GAM43186.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Scytalone_dh PF02982.14 GAM43187.1 - 5.9e-67 224.4 0.2 6.6e-67 224.3 0.2 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 GAM43187.1 - 0.00031 20.9 0.3 0.00052 20.1 0.3 1.3 1 0 0 1 1 1 1 SnoaL-like domain GMC_oxred_N PF00732.19 GAM43188.1 - 3.1e-49 168.0 0.1 4.5e-49 167.4 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM43188.1 - 1.4e-32 113.2 0.0 2.4e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 GAM43188.1 - 1.3e-05 24.6 0.0 0.00052 19.3 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM43188.1 - 3.2e-05 24.1 0.0 0.00013 22.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAM43188.1 - 0.00018 20.7 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAM43188.1 - 0.001 18.4 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 GAM43188.1 - 0.0016 17.8 0.0 0.0045 16.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM43188.1 - 0.0061 15.3 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 GAM43188.1 - 0.008 15.8 0.0 0.019 14.6 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM43188.1 - 0.0092 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 GAM43188.1 - 0.014 15.7 0.1 0.041 14.1 0.0 1.9 2 0 0 2 2 1 0 TrkA-N domain Thi4 PF01946.17 GAM43188.1 - 0.019 14.2 0.1 0.036 13.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 GAM43188.1 - 0.073 13.1 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding AflR PF08493.10 GAM43189.1 - 1.4e-14 54.3 5.8 1.4e-14 54.3 5.8 1.8 2 1 0 2 2 2 1 Aflatoxin regulatory protein Methyltransf_2 PF00891.18 GAM43191.1 - 1.1e-27 96.7 0.0 1.8e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 GAM43191.1 - 1e-05 26.1 0.2 7.2e-05 23.4 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM43191.1 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Sigma70_r4_2 PF08281.12 GAM43191.1 - 0.00067 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_IclR PF09339.10 GAM43191.1 - 0.0039 17.0 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain Methyltransf_12 PF08242.12 GAM43191.1 - 0.014 16.2 0.0 0.037 14.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain HTH_Tnp_ISL3 PF13542.6 GAM43191.1 - 0.049 13.1 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_AsnC-type PF13404.6 GAM43191.1 - 0.052 13.4 1.3 0.083 12.7 0.0 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 GAM43191.1 - 0.052 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MTS PF05175.14 GAM43191.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain TMEM234 PF10639.9 GAM43192.1 - 6.6e-35 119.6 0.2 9.3e-27 93.4 0.3 2.0 2 0 0 2 2 2 2 Putative transmembrane family 234 EamA PF00892.20 GAM43192.1 - 0.0022 18.2 6.4 0.4 10.8 4.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family PetM PF08041.11 GAM43192.1 - 0.078 12.6 1.3 0.078 12.6 1.3 2.1 3 0 0 3 3 3 0 PetM family of cytochrome b6f complex subunit 7 Chitin_synth_1 PF01644.17 GAM43193.1 - 4.9e-76 254.2 0.0 7.5e-76 253.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 GAM43193.1 - 2.9e-30 104.0 0.0 6.2e-30 103.0 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAM43193.1 - 5.7e-22 78.0 5.1 2e-18 66.3 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAM43193.1 - 1.9e-06 27.9 6.2 1.9e-06 27.9 6.2 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 MFS_1 PF07690.16 GAM43194.1 - 9.6e-31 107.0 26.3 9.6e-31 107.0 26.3 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 GAM43195.1 - 1.4e-30 106.4 24.7 1.4e-30 106.4 24.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM43195.1 - 1e-14 54.3 7.0 1e-14 54.3 7.0 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Amidase PF01425.21 GAM43196.1 - 2.8e-100 336.4 0.0 5.1e-100 335.6 0.0 1.4 1 0 0 1 1 1 1 Amidase Fungal_trans PF04082.18 GAM43196.1 - 1.1e-26 93.5 0.0 2.2e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMN_dh PF01070.18 GAM43197.1 - 2.4e-106 355.7 0.0 2.8e-106 355.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 GAM43197.1 - 7.3e-06 25.4 0.0 1.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 GAM43197.1 - 0.0029 17.1 0.1 0.0047 16.4 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAM43197.1 - 0.003 16.6 0.4 0.012 14.6 0.1 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 GAM43197.1 - 0.068 12.6 0.0 10 5.5 0.0 2.3 2 0 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 GAM43197.1 - 0.14 11.5 0.0 8.6 5.6 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG MFS_1 PF07690.16 GAM43198.1 - 3.1e-28 98.7 31.6 3.1e-28 98.7 31.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4534 PF15049.6 GAM43198.1 - 0.079 12.7 0.9 0.21 11.3 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) DUF2530 PF10745.9 GAM43198.1 - 2.3 8.5 13.8 0.095 12.9 2.3 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF2530) TPP_enzyme_N PF02776.18 GAM43199.1 - 2.5e-38 131.4 1.2 8.1e-38 129.7 0.2 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAM43199.1 - 5.7e-24 84.6 0.9 4.4e-23 81.7 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAM43199.1 - 2.6e-08 33.7 0.0 5.5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain XFP_N PF09364.10 GAM43199.1 - 0.016 14.1 0.1 0.025 13.4 0.1 1.2 1 0 0 1 1 1 0 XFP N-terminal domain Glyco_hydro_28 PF00295.17 GAM43200.1 - 3e-06 26.5 2.3 5.9e-06 25.6 2.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Alginate_lyase PF05426.12 GAM43200.1 - 0.0021 17.7 8.0 0.0052 16.4 8.0 1.6 1 1 0 1 1 1 1 Alginate lyase Beta_helix PF13229.6 GAM43200.1 - 0.12 12.3 14.6 2.2 8.1 12.9 2.9 2 1 0 2 2 2 0 Right handed beta helix region Ribosomal_L27A PF00828.19 GAM43201.1 - 3.4e-23 82.7 0.0 5e-23 82.2 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RAP PF08373.10 GAM43201.1 - 0.14 12.3 0.4 0.24 11.5 0.4 1.5 1 0 0 1 1 1 0 RAP domain LMWPc PF01451.21 GAM43202.1 - 6.1e-22 78.5 0.0 9.3e-17 61.7 0.0 2.1 2 0 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase Hydrolase_like PF13242.6 GAM43203.1 - 0.00069 19.6 0.0 0.002 18.1 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAM43203.1 - 0.18 12.1 0.0 0.45 10.8 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cupin_2 PF07883.11 GAM43204.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Fungal_trans_2 PF11951.8 GAM43205.1 - 3.5e-07 29.4 4.6 4.9e-07 28.9 4.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 GAM43206.1 - 6.1e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Pescadillo_N PF06732.11 GAM43207.1 - 1e-124 415.5 0.2 1e-124 415.5 0.2 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 GAM43207.1 - 2.8e-05 24.5 0.0 0.00013 22.3 0.0 2.2 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAM43207.1 - 0.001 19.4 0.0 0.07 13.5 0.0 3.2 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 GAM43207.1 - 0.074 13.3 0.0 0.28 11.5 0.0 2.0 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain PIG-U PF06728.13 GAM43208.1 - 2.3e-121 405.5 26.8 2.6e-121 405.3 26.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Acetyltransf_1 PF00583.25 GAM43209.1 - 3e-14 53.3 0.0 4.5e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM43209.1 - 4.4e-09 36.6 0.2 7e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM43209.1 - 1.5e-08 34.6 0.0 2.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM43209.1 - 0.0014 18.7 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 GAM43209.1 - 0.0018 18.2 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 GAM43209.1 - 0.043 14.5 0.0 0.075 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAM43209.1 - 0.21 11.7 0.0 0.41 10.8 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SOG2 PF10428.9 GAM43209.1 - 0.58 9.3 17.5 0.7 9.0 17.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Aldedh PF00171.22 GAM43210.1 - 1.2e-170 568.0 0.4 1.4e-170 567.8 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pertussis_S2S3 PF02918.15 GAM43211.1 - 0.068 13.1 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Pertussis toxin, subunit 2 and 3, C-terminal domain DUF4261 PF14080.6 GAM43211.1 - 0.17 12.0 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) MIF4G PF02854.19 GAM43212.1 - 1.1e-23 83.9 0.4 1.1e-23 83.9 0.4 2.4 3 0 0 3 3 3 1 MIF4G domain MA3 PF02847.17 GAM43212.1 - 8.7e-19 67.6 0.1 4.2e-18 65.4 0.0 2.3 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.15 GAM43213.1 - 2.9e-26 91.7 1.8 1.2e-25 89.7 1.8 1.9 1 1 0 1 1 1 1 Signal recognition particle 14kD protein Inp1 PF12634.7 GAM43214.1 - 4e-34 117.6 0.0 9.7e-34 116.3 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 FAM176 PF14851.6 GAM43214.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 FAM176 family EI24 PF07264.11 GAM43215.1 - 6.3e-14 52.6 0.6 8.9e-06 26.1 0.7 2.2 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) Pro_isomerase PF00160.21 GAM43216.1 - 3.8e-49 167.0 0.2 6.8e-49 166.2 0.2 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 GAM43216.1 - 6.8e-06 25.7 4.7 2.4e-05 23.9 0.7 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM43216.1 - 3.1e-05 23.8 9.5 0.00042 20.3 0.6 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM43216.1 - 0.00029 20.7 11.4 0.0003 20.7 1.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM43216.1 - 0.00069 19.7 2.7 0.019 15.1 1.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM43216.1 - 0.02 15.6 11.8 0.27 11.9 8.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM43216.1 - 0.094 13.0 7.5 5.2 7.4 3.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM43216.1 - 0.12 13.2 9.8 0.38 11.7 3.2 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat UbiD PF01977.16 GAM43217.1 - 2.9e-09 36.3 0.0 4.1e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase DDE_1 PF03184.19 GAM43218.1 - 5e-41 140.2 2.4 3.3e-40 137.6 0.2 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_ABP1_N PF18107.1 GAM43218.1 - 2.3e-20 72.1 4.9 3.1e-20 71.7 3.1 2.2 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 GAM43218.1 - 6.7e-11 42.1 2.3 7.6e-11 41.9 0.7 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_Tnp_Tc3_2 PF01498.18 GAM43218.1 - 0.0061 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 GAM43218.1 - 0.13 12.9 0.8 0.39 11.4 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Tyr_Deacylase PF02580.16 GAM43219.1 - 3.5e-51 173.5 0.2 4.5e-51 173.2 0.2 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Flg_hook PF02120.16 GAM43219.1 - 0.047 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Not3 PF04065.15 GAM43220.1 - 6.4e-85 284.3 19.4 9e-85 283.8 19.4 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 GAM43220.1 - 1.9e-44 150.9 10.7 5.3e-44 149.5 10.7 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family RPW8 PF05659.11 GAM43220.1 - 0.071 12.8 8.2 0.023 14.4 1.8 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 MCM3AP_GANP PF16769.5 GAM43220.1 - 0.084 11.1 8.1 0.12 10.6 8.1 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP DUF2373 PF10180.9 GAM43220.1 - 0.12 12.2 3.3 0.3 11.0 3.3 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) LPP PF04728.13 GAM43220.1 - 0.15 12.5 0.9 0.55 10.7 0.5 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF1192 PF06698.11 GAM43220.1 - 0.16 12.0 4.7 0.067 13.3 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Cep57_MT_bd PF06657.13 GAM43220.1 - 0.79 10.2 5.9 15 6.1 0.7 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Mu-like_Pro PF10123.9 GAM43220.1 - 1.2 8.7 8.1 2.3 7.7 8.1 1.4 1 0 0 1 1 1 0 Mu-like prophage I protein Spore_III_AB PF09548.10 GAM43220.1 - 8.8 6.4 10.2 1.6 8.8 5.2 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) 5_3_exonuc PF01367.20 GAM43220.1 - 9 7.0 6.2 52 4.5 0.5 2.8 2 1 1 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold FAD_binding_3 PF01494.19 GAM43221.1 - 2.7e-52 178.2 0.0 3.3e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM43221.1 - 6e-08 32.7 0.2 4.6e-05 23.2 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM43221.1 - 0.0001 21.2 0.1 0.00015 20.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 GAM43221.1 - 0.0015 17.7 0.3 0.035 13.2 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GAM43221.1 - 0.0036 17.5 0.0 0.0096 16.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM43221.1 - 0.017 14.3 0.1 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM43221.1 - 0.023 13.9 0.0 0.079 12.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM43221.1 - 0.024 15.2 0.1 0.056 14.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Tetrabrachion PF11401.8 GAM43221.1 - 0.12 12.4 0.2 1.9 8.6 0.1 2.5 2 0 0 2 2 2 0 Tetrabrachion Thi4 PF01946.17 GAM43221.1 - 0.16 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 GAM43221.1 - 0.23 11.3 0.6 0.77 9.6 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DLH PF01738.18 GAM43222.1 - 2.1e-18 66.7 0.0 2.6e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 GAM43222.1 - 0.13 11.9 0.1 1.3 8.6 0.1 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold K_oxygenase PF13434.6 GAM43223.1 - 2.4e-14 53.2 0.2 5.2e-10 39.0 0.0 3.1 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAM43223.1 - 1.8e-12 47.2 0.0 1.5e-09 37.5 0.0 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAM43223.1 - 6.8e-12 44.6 0.1 9.8e-11 40.8 0.1 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 GAM43223.1 - 1.3e-08 35.0 0.0 4.1e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM43223.1 - 1.7e-06 27.9 0.0 3.1e-05 23.7 0.0 2.8 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM43223.1 - 3.2e-06 26.6 0.0 0.00071 18.9 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM43223.1 - 0.00037 20.5 0.0 0.0079 16.2 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAM43223.1 - 0.0034 17.9 0.1 0.025 15.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 GAM43223.1 - 0.25 11.8 0.6 9 6.8 0.0 3.0 3 0 0 3 3 3 0 Putative NAD(P)-binding EHN PF06441.12 GAM43224.1 - 1.4e-26 93.0 0.0 2.5e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 GAM43224.1 - 9.1e-12 45.2 0.0 1.4e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM43224.1 - 0.00018 22.2 5.3 0.00051 20.7 4.9 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Dak1 PF02733.17 GAM43225.1 - 6.5e-103 343.9 2.1 1e-102 343.2 2.1 1.3 1 0 0 1 1 1 1 Dak1 domain Sugar_tr PF00083.24 GAM43225.1 - 1.3e-99 334.1 24.5 1.8e-99 333.7 24.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Dak2 PF02734.17 GAM43225.1 - 3.1e-34 118.4 0.7 5.5e-34 117.6 0.7 1.3 1 0 0 1 1 1 1 DAK2 domain ADH_N PF08240.12 GAM43225.1 - 3e-27 94.6 1.9 3e-27 94.6 1.9 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 GAM43225.1 - 8.9e-27 93.9 44.9 4.5e-26 91.6 18.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.26 GAM43225.1 - 1.6e-12 47.5 0.0 3.7e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAM43225.1 - 9.6e-05 22.0 0.2 0.00038 20.0 0.2 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 GAM43226.1 - 7.7e-14 51.8 0.0 1.5e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM43226.1 - 3e-08 34.8 0.0 6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM43226.1 - 1.8e-06 27.8 0.3 1.3e-05 25.0 0.2 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Fungal_trans_2 PF11951.8 GAM43227.1 - 7.8e-06 24.9 0.6 1.2e-05 24.3 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM43227.1 - 0.045 13.9 0.9 0.09 12.9 0.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1772 PF08592.11 GAM43228.1 - 8.9e-28 97.3 8.3 1.6e-27 96.5 8.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) NMT1_3 PF16868.5 GAM43229.1 - 4.6e-15 55.8 0.0 6e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family SBP_bac_11 PF13531.6 GAM43229.1 - 0.17 11.6 0.0 0.9 9.2 0.0 1.9 1 1 0 2 2 2 0 Bacterial extracellular solute-binding protein Fungal_trans PF04082.18 GAM43230.1 - 3.7e-12 45.8 0.3 7.3e-12 44.9 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM43230.1 - 6e-08 32.7 10.7 1.3e-07 31.6 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1449 PF07290.11 GAM43231.1 - 0.025 14.2 0.4 0.081 12.5 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) UCR_Fe-S_N PF10399.9 GAM43231.1 - 2.9 7.3 8.3 0.19 11.1 2.6 2.1 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal CE2_N PF17996.1 GAM43232.1 - 1.1e-17 63.9 0.0 1.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 GAM43232.1 - 1.4e-12 48.3 1.5 2.6e-12 47.5 1.5 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.18 GAM43232.1 - 9.6e-10 38.2 13.4 2e-09 37.3 13.4 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.22 GAM43232.1 - 3.1e-06 27.3 0.1 5.2e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_43 PF04616.14 GAM43233.1 - 2.2e-55 188.0 3.3 2.4e-55 187.9 2.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 GAM43233.1 - 2e-05 24.4 0.0 3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain MFS_1 PF07690.16 GAM43234.1 - 2.1e-28 99.3 24.0 2.1e-28 99.3 24.0 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM43234.1 - 5.3e-12 45.3 15.0 5.3e-12 45.3 15.0 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAM43234.1 - 3.4e-07 29.1 6.6 3.4e-07 29.1 6.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1240 PF06836.12 GAM43234.1 - 0.041 14.4 0.3 0.041 14.4 0.3 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1240) FAD_binding_3 PF01494.19 GAM43235.1 - 1.8e-27 96.5 0.0 2e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM43235.1 - 4.3e-09 36.4 1.0 2.3e-06 27.4 0.6 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM43235.1 - 4.7e-05 22.3 0.4 0.00013 20.8 0.4 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 GAM43235.1 - 0.00012 22.3 0.4 0.00024 21.3 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM43235.1 - 0.00025 20.4 0.0 0.00045 19.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM43235.1 - 0.00069 19.0 0.6 0.0033 16.7 0.4 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 GAM43235.1 - 0.0012 18.4 0.1 0.0022 17.6 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 GAM43235.1 - 0.0032 16.8 0.5 0.0074 15.6 0.3 1.7 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 GAM43235.1 - 0.007 15.5 0.2 0.0098 15.0 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.18 GAM43235.1 - 0.018 14.9 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 GAM43235.1 - 0.021 15.4 0.7 0.081 13.5 0.2 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM43235.1 - 0.022 13.9 0.6 0.034 13.2 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain Glu_dehyd_C PF16912.5 GAM43235.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 GAM43235.1 - 0.1 13.0 0.1 0.18 12.2 0.1 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Big_7 PF17957.1 GAM43237.1 - 0.054 14.3 0.6 0.35 11.7 0.1 2.5 3 0 0 3 3 3 0 Bacterial Ig domain Glyco_hydro_26 PF02156.15 GAM43238.1 - 1.1e-06 28.3 0.9 1.9e-06 27.6 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Pro-kuma_activ PF09286.11 GAM43239.1 - 3.9e-40 137.4 0.0 1.5e-38 132.3 0.0 2.3 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain DUF5609 PF18429.1 GAM43239.1 - 0.11 12.3 0.0 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5609) GST_N_3 PF13417.6 GAM43240.1 - 1.1e-12 48.2 0.0 2.2e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAM43240.1 - 2e-10 40.9 0.0 5.2e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM43240.1 - 1e-09 38.5 0.1 1.7e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM43240.1 - 1.4e-09 38.0 0.3 3.4e-09 36.8 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM43240.1 - 3.3e-08 33.7 0.0 6.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM43240.1 - 1.9e-05 24.6 2.1 2.9e-05 24.0 0.6 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GAM43240.1 - 0.0023 18.5 0.0 0.22 12.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GAM43240.1 - 0.043 14.6 0.0 0.11 13.2 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain MetRS-N PF09635.10 GAM43240.1 - 0.14 12.7 0.0 0.37 11.4 0.0 1.7 2 0 0 2 2 2 0 MetRS-N binding domain RhoGEF PF00621.20 GAM43241.1 - 1.1e-36 126.8 0.1 2.4e-36 125.7 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain Peptidase_C48 PF02902.19 GAM43241.1 - 1.1e-15 58.1 0.0 2.8e-15 56.7 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 GAM43241.1 - 0.058 13.4 0.1 0.88 9.7 0.1 2.5 2 0 0 2 2 2 0 Domian of unknown function (DUF4951) MSP1_C PF07462.11 GAM43241.1 - 8.7 4.9 6.8 0.26 9.9 0.3 1.7 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus PBP PF01161.20 GAM43242.1 - 3.2e-15 56.6 0.0 3.9e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Telomerase_RBD PF12009.8 GAM43243.1 - 2.2e-45 154.1 0.1 6e-45 152.6 0.1 1.8 1 1 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain Aldo_ket_red PF00248.21 GAM43243.1 - 2e-25 89.6 0.0 3.4e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family RVT_1 PF00078.27 GAM43243.1 - 3.4e-16 59.4 0.1 1.7e-11 44.1 0.0 2.9 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.16 GAM43244.1 - 2.7e-35 121.9 27.2 2.7e-35 121.9 27.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 GAM43245.1 - 5.5e-19 68.6 0.0 1.7e-18 67.0 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM43245.1 - 3.8e-09 36.2 0.1 5.4e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM43245.1 - 8.5e-09 35.0 0.2 6.6e-08 32.0 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 GAM43245.1 - 3e-07 30.3 0.0 0.0002 21.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM43245.1 - 4.7e-06 26.7 0.1 1e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAM43245.1 - 3.4e-05 24.3 0.4 0.0031 18.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM43245.1 - 5.2e-05 22.1 0.0 0.00015 20.6 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 GAM43245.1 - 7.8e-05 22.2 0.1 0.00019 20.9 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAM43245.1 - 0.0017 17.7 0.1 0.0027 17.0 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM43245.1 - 0.002 17.3 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAM43245.1 - 0.0053 16.1 0.1 0.0089 15.3 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 GAM43245.1 - 0.024 14.0 0.0 0.35 10.1 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 GAM43245.1 - 0.025 13.8 0.1 0.046 13.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 GAM43245.1 - 0.081 11.8 0.1 0.24 10.2 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 GAM43245.1 - 0.17 10.9 0.1 0.36 9.8 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 GAM43245.1 - 0.18 11.3 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain p450 PF00067.22 GAM43246.1 - 6.9e-79 265.7 0.0 9.4e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_5 PF00266.19 GAM43247.1 - 4.1e-28 98.4 0.0 5.5e-18 65.1 0.0 2.1 1 1 0 2 2 2 2 Aminotransferase class-V MFS_1 PF07690.16 GAM43248.1 - 6e-43 147.1 37.3 6e-43 147.1 37.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM43248.1 - 8.4e-12 44.7 5.9 8.4e-12 44.7 5.9 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 GAM43248.1 - 3e-07 30.1 5.3 3e-07 30.1 5.3 2.5 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 GAM43248.1 - 0.17 10.1 14.8 0.059 11.7 1.0 3.2 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF2583 PF10762.9 GAM43248.1 - 0.22 11.9 1.0 0.79 10.2 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) Glyco_hydro_31 PF01055.26 GAM43249.1 - 2.3e-114 383.0 1.7 3.4e-114 382.4 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 GAM43249.1 - 0.001 19.3 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 GAM43249.1 - 0.0015 18.8 1.5 0.0083 16.4 0.1 2.8 3 1 0 3 3 3 1 Galactose mutarotase-like SKG6 PF08693.10 GAM43250.1 - 0.00011 21.6 2.9 0.00011 21.6 2.9 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 GAM43250.1 - 0.00019 21.5 3.7 0.00038 20.6 3.7 1.4 1 0 0 1 1 1 1 Podoplanin Glycophorin_A PF01102.18 GAM43250.1 - 0.0049 17.1 0.8 0.01 16.0 0.8 1.5 1 0 0 1 1 1 1 Glycophorin A DUF4448 PF14610.6 GAM43250.1 - 0.0078 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Stevor PF17410.2 GAM43250.1 - 0.054 13.0 1.5 0.073 12.6 1.5 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Amnionless PF14828.6 GAM43250.1 - 0.063 12.1 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless TrbC PF04956.13 GAM43250.1 - 1.1 9.5 8.2 2.9 8.2 8.2 1.8 1 1 0 1 1 1 0 TrbC/VIRB2 family VSP PF03302.13 GAM43250.1 - 1.5 7.6 20.0 2.8 6.7 20.0 1.4 1 1 0 1 1 1 0 Giardia variant-specific surface protein MGC-24 PF05283.11 GAM43250.1 - 5.7 7.4 19.8 0.19 12.2 8.5 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CE2_N PF17996.1 GAM43251.1 - 2.6e-19 69.2 0.2 6.6e-19 67.9 0.1 1.7 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 GAM43251.1 - 3.8e-16 60.0 2.5 5.2e-16 59.6 2.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAM43251.1 - 1.1e-06 28.8 0.1 1.6e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Aminotran_3 PF00202.21 GAM43252.1 - 1.2e-89 300.8 0.0 1.8e-89 300.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Abhydrolase_4 PF08386.10 GAM43252.1 - 3.3e-19 68.9 0.0 8.6e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein MFS_1 PF07690.16 GAM43252.1 - 3.6e-18 65.6 34.0 1.1e-17 64.0 34.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 GAM43252.1 - 2.9e-12 46.8 0.0 7.6e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Plasmid_RAQPRD PF09686.10 GAM43253.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.5 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF948 PF06103.11 GAM43253.1 - 0.062 13.6 2.2 0.28 11.5 0.7 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SapB_1 PF05184.15 GAM43253.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Saposin-like type B, region 1 Baculo_PEP_C PF04513.12 GAM43253.1 - 1.3 9.1 14.8 0.57 10.2 8.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NmrA PF05368.13 GAM43254.1 - 3.8e-20 72.5 0.0 7.2e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM43254.1 - 3.3e-13 49.9 0.1 7.5e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding S1-P1_nuclease PF02265.16 GAM43255.1 - 1.3e-70 238.1 0.0 1.5e-70 237.9 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease ThiF PF00899.21 GAM43256.1 - 6.1e-61 205.9 0.0 8.8e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 GAM43256.1 - 1.9e-10 41.2 0.0 4.4e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain DPBB_1 PF03330.18 GAM43258.1 - 3.6e-05 23.9 0.1 6.5e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Lytic transglycolase Big_9 PF17963.1 GAM43258.1 - 0.11 13.2 0.7 0.11 13.2 0.7 2.0 2 0 0 2 2 2 0 Bacterial Ig domain NmrA PF05368.13 GAM43259.1 - 5.2e-18 65.5 0.1 6.6e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM43259.1 - 5.2e-16 59.1 0.0 1.1e-15 58.0 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 GAM43259.1 - 0.00025 20.6 0.0 0.0007 19.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.22 GAM43259.1 - 0.0006 20.6 0.0 0.0013 19.5 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold KR PF08659.10 GAM43259.1 - 0.0031 17.4 0.0 0.028 14.3 0.0 2.1 2 0 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.24 GAM43259.1 - 0.016 15.7 0.0 0.13 12.7 0.0 2.5 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 GAM43259.1 - 0.13 12.5 0.1 1.4 9.2 0.0 2.6 4 1 0 4 4 4 0 TrkA-N domain 3Beta_HSD PF01073.19 GAM43259.1 - 0.15 11.0 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox_2 PF07992.14 GAM43260.1 - 4.1e-19 68.9 0.0 2.3e-12 46.8 0.0 2.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM43260.1 - 7e-05 21.7 0.0 0.002 16.9 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 GAM43260.1 - 0.00092 18.4 0.2 0.0076 15.4 0.0 2.1 1 1 1 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 GAM43260.1 - 0.0028 17.6 0.4 0.81 9.7 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GAM43260.1 - 0.003 16.9 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 GAM43260.1 - 0.0032 16.6 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 GAM43260.1 - 0.0039 16.5 0.0 0.26 10.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAM43260.1 - 0.034 13.5 0.1 0.069 12.5 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 GAM43260.1 - 0.038 13.2 0.1 0.063 12.5 0.1 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 GAM43260.1 - 0.04 14.1 0.1 0.087 13.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAM43260.1 - 0.044 12.8 0.0 0.23 10.4 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.6 GAM43260.1 - 0.051 12.7 0.1 2 7.5 0.0 2.4 1 1 2 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 GAM43260.1 - 0.11 12.0 0.6 0.48 9.9 0.6 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase Fer2_3 PF13085.6 GAM43261.1 - 1.7e-31 108.4 0.0 2.9e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 GAM43261.1 - 1.5e-08 35.0 6.5 1.5e-08 35.0 6.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 GAM43261.1 - 6.1e-07 29.5 3.8 6.1e-07 29.5 3.8 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 GAM43261.1 - 1.9e-06 28.2 8.3 1.9e-06 28.2 8.3 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 GAM43261.1 - 0.0035 17.9 4.8 0.0035 17.9 4.8 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 GAM43261.1 - 0.013 15.4 0.4 0.013 15.4 0.4 2.3 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 GAM43261.1 - 0.76 10.0 6.5 0.72 10.1 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 GAM43261.1 - 2.9 8.1 12.4 33 4.8 5.2 2.9 2 1 2 4 4 4 0 4Fe-4S dicluster domain Aldedh PF00171.22 GAM43262.1 - 1.8e-71 241.1 0.0 3.8e-47 160.8 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Glyoxalase PF00903.25 GAM43263.1 - 1e-23 83.9 0.7 1.3e-15 57.7 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAM43263.1 - 5.7e-14 52.3 0.1 1e-06 29.0 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 GAM43263.1 - 1.4e-07 31.8 0.0 0.011 15.8 0.1 2.9 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 GAM43263.1 - 0.00018 21.7 0.1 0.002 18.3 0.0 2.4 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_6 PF18029.1 GAM43263.1 - 0.026 15.3 0.1 0.61 10.9 0.0 2.4 2 1 0 2 2 2 0 Glyoxalase-like domain HNH PF01844.23 GAM43263.1 - 0.14 12.4 1.4 0.29 11.3 1.4 1.4 1 0 0 1 1 1 0 HNH endonuclease DUF2530 PF10745.9 GAM43264.1 - 6.8 7.0 10.2 0.64 10.3 0.7 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) Methyltransf_2 PF00891.18 GAM43265.1 - 5.2e-25 88.0 0.0 8e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Sigma70_r4 PF04545.16 GAM43265.1 - 0.034 13.6 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2805 PF10985.8 GAM43265.1 - 0.037 14.4 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Methyltransf_4 PF02390.17 GAM43265.1 - 0.14 11.6 0.1 0.75 9.2 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase Sugar_tr PF00083.24 GAM43266.1 - 1.3e-95 320.9 25.1 1.6e-95 320.7 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM43266.1 - 5e-26 91.4 35.5 5.4e-21 74.9 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 GAM43266.1 - 0.00014 20.9 0.2 0.00031 19.8 0.2 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 GAM43266.1 - 0.0038 15.7 4.7 0.019 13.4 1.1 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 GAM43266.1 - 0.14 12.7 1.5 0.58 10.7 1.5 2.0 1 0 0 1 1 1 0 Phage holin family 2 F_bP_aldolase PF01116.20 GAM43267.1 - 6.3e-70 235.8 0.5 1.2e-67 228.3 0.4 2.0 1 1 1 2 2 2 2 Fructose-bisphosphate aldolase class-II Methyltransf_24 PF13578.6 GAM43267.1 - 0.077 14.0 0.0 0.15 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_11 PF14833.6 GAM43268.1 - 1.1e-39 135.4 0.3 4.9e-29 101.0 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 GAM43268.1 - 8.3e-38 130.0 0.0 1.6e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 GAM43268.1 - 0.00057 19.8 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GAM43268.1 - 0.00087 19.8 0.0 0.0029 18.1 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh PF00984.19 GAM43268.1 - 0.0062 16.7 0.2 0.22 11.7 0.0 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Git3 PF11710.8 GAM43269.1 - 4.2e-29 101.8 12.6 1.7e-28 99.8 12.6 1.9 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 GAM43269.1 - 2.1e-15 56.6 0.1 6.4e-15 55.0 0.1 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 GAM43269.1 - 3.8e-06 26.4 9.6 4.6e-06 26.1 9.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 GAM43269.1 - 6.7e-06 25.4 11.3 9.3e-06 25.0 11.3 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Glyco_hydro_30 PF02055.16 GAM43270.1 - 1.2e-11 44.2 0.0 1.8e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 GAM43270.1 - 2.5e-09 36.8 0.1 3.8e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 GAM43270.1 - 6.5e-08 32.7 0.4 1.6e-07 31.5 0.4 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydr_30_2 PF14587.6 GAM43270.1 - 0.031 13.9 3.2 0.054 13.1 0.0 2.5 3 0 0 3 3 3 0 O-Glycosyl hydrolase family 30 Big_7 PF17957.1 GAM43270.1 - 1.8 9.4 6.9 6.2 7.7 0.1 3.7 3 1 1 4 4 4 0 Bacterial Ig domain FAD_binding_4 PF01565.23 GAM43271.1 - 1.4e-23 83.1 2.1 2.5e-23 82.4 2.1 1.4 1 0 0 1 1 1 1 FAD binding domain G_glu_transpept PF01019.21 GAM43273.1 - 4.9e-168 560.1 0.0 5.7e-168 559.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MFS_1 PF07690.16 GAM43274.1 - 6.3e-19 68.1 36.1 2.6e-17 62.8 34.8 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM43274.1 - 9.7e-06 24.3 7.6 2.2e-05 23.1 7.6 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SLX9 PF15341.6 GAM43275.1 - 2.6e-36 124.9 10.3 3.2e-36 124.6 10.3 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 NAD_Gly3P_dh_N PF01210.23 GAM43276.1 - 4.9e-47 159.8 0.0 1e-46 158.8 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 GAM43276.1 - 9.3e-44 149.1 0.3 1.5e-43 148.5 0.3 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 GAM43276.1 - 0.023 15.3 0.0 11 6.7 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent hDGE_amylase PF14701.6 GAM43277.1 - 3e-185 616.5 0.0 3.8e-185 616.2 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 GAM43277.1 - 1.4e-122 409.4 0.0 3.6e-122 408.0 0.0 1.7 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 GAM43277.1 - 2.1e-86 289.7 0.0 3.5e-86 289.0 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 GAM43277.1 - 1.8e-31 108.1 0.0 3.6e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 GAM43277.1 - 0.00067 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, catalytic domain F-box-like PF12937.7 GAM43278.1 - 7.1e-05 22.6 0.1 0.00017 21.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like RSN1_7TM PF02714.15 GAM43279.1 - 8.8e-82 274.5 24.2 1.5e-81 273.7 24.2 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAM43279.1 - 3.1e-37 127.7 0.1 3.1e-37 127.7 0.1 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAM43279.1 - 3e-28 99.2 0.2 5.7e-28 98.3 0.2 1.5 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 GAM43279.1 - 0.0065 15.4 0.8 0.0065 15.4 0.8 2.2 1 1 0 2 2 2 1 Calcium-activated chloride channel DUF4396 PF14342.6 GAM43279.1 - 2.4 8.5 8.7 1.5 9.1 2.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4396) DAHP_synth_1 PF00793.20 GAM43280.1 - 1.7e-104 348.6 0.0 1.9e-104 348.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ank_2 PF12796.7 GAM43281.1 - 2.4e-212 688.2 28.6 1.6e-18 67.0 0.0 14.9 3 1 14 18 18 18 17 Ankyrin repeats (3 copies) Ank PF00023.30 GAM43281.1 - 9.3e-155 497.0 13.2 6.1e-07 29.6 0.0 26.6 26 0 0 26 26 26 25 Ankyrin repeat Ank_4 PF13637.6 GAM43281.1 - 1.3e-146 475.2 14.0 6e-13 49.0 0.0 19.2 8 5 13 21 21 21 20 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM43281.1 - 3.7e-129 404.8 7.0 1.6e-05 24.9 0.0 25.5 25 0 0 25 25 25 23 Ankyrin repeat Ank_5 PF13857.6 GAM43281.1 - 2.1e-105 343.4 31.3 2.6e-11 43.5 0.6 20.3 7 6 11 21 21 21 19 Ankyrin repeats (many copies) HET PF06985.11 GAM43281.1 - 2.2e-06 28.1 1.3 0.00034 21.0 0.1 2.7 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) VWA_3_C PF18571.1 GAM43281.1 - 0.00066 19.5 4.4 3.9 7.4 0.0 7.7 10 0 0 10 10 10 1 von Willebrand factor type A C-terminal domain GATase_7 PF13537.6 GAM43281.1 - 0.051 13.5 0.0 66 3.4 0.0 4.9 3 1 1 4 4 4 0 Glutamine amidotransferase domain SAND PF01342.21 GAM43281.1 - 0.068 12.9 0.0 57 3.5 0.0 4.7 4 0 0 4 4 4 0 SAND domain SUB1_ProdP9 PF18213.1 GAM43282.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 Pal1 PF08316.11 GAM43283.1 - 3.5 8.4 7.2 11 6.8 7.2 2.0 1 1 0 1 1 1 0 Pal1 cell morphology protein AIG2_2 PF13772.6 GAM43284.1 - 0.0021 18.4 0.1 0.0084 16.5 0.1 2.0 2 0 0 2 2 2 1 AIG2-like family GATA-N PF05349.12 GAM43284.1 - 0.042 14.1 0.0 0.11 12.8 0.0 1.6 2 0 0 2 2 2 0 GATA-type transcription activator, N-terminal Cytochrom_C1 PF02167.15 GAM43285.1 - 1.3e-92 309.5 0.0 1.7e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 GAM43285.1 - 0.0077 16.5 0.1 0.017 15.4 0.1 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Phi-29_GP3 PF05435.11 GAM43285.1 - 0.09 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 Cytochrom_C PF00034.21 GAM43285.1 - 0.13 13.5 1.7 0.6 11.3 0.3 2.8 3 2 0 3 3 3 0 Cytochrome c AAA PF00004.29 GAM43286.1 - 1.3e-24 87.1 0.0 3.1e-24 85.9 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 GAM43286.1 - 2.1e-14 53.9 0.0 6.1e-14 52.4 0.0 1.7 2 0 0 2 2 2 1 BCS1 N terminal RuvB_N PF05496.12 GAM43286.1 - 5.7e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAM43286.1 - 0.006 16.6 0.0 0.025 14.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAM43286.1 - 0.0094 15.1 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 GAM43286.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAM43286.1 - 0.016 15.6 0.0 0.037 14.4 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 GAM43286.1 - 0.017 15.5 0.1 0.065 13.6 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain TIP49 PF06068.13 GAM43286.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Sec10 PF07393.11 GAM43287.1 - 3.4e-164 548.1 0.0 4.2e-164 547.8 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 GAM43287.1 - 1.2e-05 25.1 0.0 3.3e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM43287.1 - 3.1e-05 23.7 0.0 6.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAM43287.1 - 0.02 14.8 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 F-box Epimerase PF01370.21 GAM43288.1 - 4.6e-19 68.8 0.0 9.9e-19 67.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM43288.1 - 1.9e-16 59.9 0.0 3.6e-16 59.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAM43288.1 - 3.5e-12 46.0 0.1 2.5e-11 43.3 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 GAM43288.1 - 2.4e-10 40.3 0.0 4.1e-10 39.6 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 GAM43288.1 - 4.2e-08 33.3 0.0 7.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAM43288.1 - 3.5e-07 30.3 0.0 5.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 GAM43288.1 - 1.1e-05 25.0 0.0 2.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 GAM43288.1 - 9.4e-05 21.7 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 GAM43288.1 - 0.00033 20.3 0.4 0.0021 17.7 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 GAM43288.1 - 0.042 12.9 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain CAP PF00188.26 GAM43289.1 - 1.4e-22 80.8 2.1 1.9e-22 80.4 2.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Cullin PF00888.22 GAM43289.1 - 0.28 9.7 0.0 0.33 9.5 0.0 1.1 1 0 0 1 1 1 0 Cullin family WD40 PF00400.32 GAM43290.1 - 1.1e-56 187.5 23.2 3.8e-10 40.2 0.0 9.0 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM43290.1 - 1.5e-24 86.1 2.1 0.00042 20.6 0.0 6.6 3 3 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM43290.1 - 4.3e-08 33.3 0.1 0.0041 17.0 0.0 3.8 1 1 3 5 5 5 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAM43290.1 - 1.9e-06 27.1 0.3 0.13 11.2 0.0 4.1 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAM43290.1 - 3.7e-06 25.9 3.7 4.4 5.8 0.0 5.2 2 2 2 5 5 5 3 Nucleoporin Nup120/160 NLE PF08154.12 GAM43290.1 - 0.00018 22.0 0.1 0.00033 21.1 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40_like PF17005.5 GAM43290.1 - 0.00025 20.5 0.0 2.9 7.1 0.0 4.2 3 2 2 5 5 5 2 WD40-like domain PD40 PF07676.12 GAM43290.1 - 0.0092 15.9 0.1 24 5.0 0.0 4.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF5046 PF16465.5 GAM43290.1 - 0.018 14.5 0.0 3.2 7.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5046) DUF4550 PF15084.6 GAM43290.1 - 0.024 15.0 0.3 0.14 12.6 0.2 2.4 2 1 1 3 3 2 0 Domain of unknown function (DUF4550) Nbas_N PF15492.6 GAM43290.1 - 0.051 12.9 0.2 9.7 5.4 0.0 3.3 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal 120_Rick_ant PF12574.8 GAM43290.1 - 0.21 10.7 0.9 7.9 5.6 0.0 2.3 2 0 0 2 2 2 0 120 KDa Rickettsia surface antigen MutS_V PF00488.21 GAM43291.1 - 1e-62 211.6 0.3 1.7e-62 210.8 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAM43291.1 - 1.5e-31 110.1 4.2 1.5e-31 110.1 4.2 1.9 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 GAM43291.1 - 2.5e-09 37.5 0.1 5.9e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 GAM43291.1 - 4.2e-09 36.6 0.2 1.1e-08 35.3 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_30 PF13604.6 GAM43291.1 - 0.036 13.8 0.0 0.15 11.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_27 PF13514.6 GAM43291.1 - 0.098 12.2 0.0 0.52 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Vps51 PF08700.11 GAM43292.1 - 0.14 12.3 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Vps51/Vps67 SWIB PF02201.18 GAM43293.1 - 5.3e-29 99.9 0.4 1.4e-28 98.6 0.1 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 GAM43293.1 - 9.6e-12 44.6 1.0 4.9e-11 42.4 0.1 2.2 2 0 0 2 2 2 1 DEK C terminal domain Ndc1_Nup PF09531.10 GAM43293.1 - 3.5 6.2 5.7 3.9 6.0 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.12 GAM43293.1 - 4.2 7.1 9.3 5.6 6.7 9.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF2A PF08662.11 GAM43294.1 - 1.3e-34 119.8 0.7 9e-32 110.5 0.3 3.6 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 GAM43294.1 - 2.5e-08 33.6 0.0 5.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM83 PF07894.12 GAM43294.1 - 0.012 15.2 0.2 0.021 14.4 0.2 1.4 1 0 0 1 1 1 0 FAM83 A-H WD40 PF00400.32 GAM43294.1 - 0.053 14.4 1.1 2.2 9.3 0.1 3.9 5 0 0 5 5 5 0 WD domain, G-beta repeat Fungal_trans PF04082.18 GAM43295.1 - 1.3e-07 31.0 0.1 4e-07 29.3 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.22 GAM43296.1 - 1.1e-43 149.7 0.0 1.6e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 GAM43296.1 - 4.1e-16 59.4 0.0 4.1e-07 29.9 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM43296.1 - 1.1e-10 42.6 0.0 1.8e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family pKID PF02173.17 GAM43296.1 - 0.03 13.8 0.1 0.059 12.8 0.1 1.4 1 0 0 1 1 1 0 pKID domain Hydrolase_4 PF12146.8 GAM43296.1 - 0.11 11.8 0.0 5.3 6.2 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 p450 PF00067.22 GAM43297.1 - 2.5e-65 221.1 0.0 3.2e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 GAM43298.1 - 3.2e-22 78.9 60.2 3.8e-21 75.4 47.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAM43298.1 - 0.056 12.3 23.3 0.026 13.4 19.9 2.1 1 1 1 2 2 2 0 MFS_1 like family Scytalone_dh PF02982.14 GAM43299.1 - 3.2e-27 95.3 0.2 3.7e-27 95.1 0.2 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 GAM43299.1 - 0.00011 22.3 0.0 0.00013 22.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Peptidase_M15_4 PF13539.6 GAM43299.1 - 0.13 12.8 0.1 3 8.4 0.0 2.2 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase MFS_1 PF07690.16 GAM43300.1 - 3.4e-25 88.7 38.5 3.4e-25 88.7 38.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM43300.1 - 8.2e-11 41.0 24.4 1.6e-10 40.1 24.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 GAM43300.1 - 0.11 12.7 0.2 0.11 12.7 0.2 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF1453 PF07301.11 GAM43300.1 - 0.37 10.8 8.8 0.56 10.2 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1453) Ank_2 PF12796.7 GAM43301.1 - 5.8e-27 94.1 4.7 1.7e-10 41.3 0.0 4.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM43301.1 - 3.8e-23 81.5 2.6 1.9e-05 25.1 0.0 7.0 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM43301.1 - 1.6e-21 76.0 3.4 9.2e-07 29.0 0.1 6.2 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAM43301.1 - 4.1e-15 55.5 15.4 0.042 14.3 0.5 8.6 8 1 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 GAM43301.1 - 6e-14 50.8 2.4 2 9.3 0.0 8.0 7 0 0 7 7 7 4 Ankyrin repeat DUF1843 PF08898.10 GAM43301.1 - 3.6 8.2 14.2 1.3 9.6 0.4 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) ADH_N PF08240.12 GAM43302.1 - 1.2e-22 79.9 0.0 2.7e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 GAM43302.1 - 0.0021 17.6 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 GAM43302.1 - 0.023 14.0 0.1 0.036 13.4 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.13 GAM43303.1 - 2.2e-56 191.1 0.5 2.7e-56 190.7 0.5 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM43303.1 - 8.4e-19 68.2 0.0 1.2e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAM43303.1 - 0.0061 15.6 0.0 0.0083 15.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans PF04082.18 GAM43304.1 - 1.2e-11 44.1 0.3 3.3e-11 42.7 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM43304.1 - 0.25 11.5 2.9 0.41 10.8 2.9 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrolase_4 PF12146.8 GAM43305.1 - 7.6e-09 35.2 0.2 5.1e-05 22.6 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM43305.1 - 0.0014 18.3 0.1 0.0098 15.6 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM43305.1 - 0.037 14.6 0.1 0.046 14.3 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAM43305.1 - 0.041 13.3 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family BAAT_C PF08840.11 GAM43305.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3602 PF12223.8 GAM43306.1 - 2.4e-16 60.1 10.6 6.1e-12 46.0 1.9 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 GAM43306.1 - 0.47 10.0 4.7 0.96 9.0 0.3 2.7 1 1 2 3 3 3 0 GTP1/OBG Far-17a_AIG1 PF04750.14 GAM43307.1 - 1.9e-59 200.4 10.1 2.2e-59 200.2 10.1 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF5336 PF17270.2 GAM43307.1 - 0.023 14.4 1.6 0.049 13.3 0.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5336) Pam17 PF08566.10 GAM43308.1 - 9.5e-68 227.2 0.0 1.6e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Herpes_UL73 PF03554.13 GAM43308.1 - 0.43 10.6 4.3 0.26 11.3 1.8 2.0 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein GMC_oxred_C PF05199.13 GAM43309.1 - 4.7e-31 108.3 0.0 7e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 GAM43309.1 - 9.5e-17 61.3 0.3 1.6e-16 60.5 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase HHH_5 PF14520.6 GAM43309.1 - 0.067 13.8 0.0 0.22 12.2 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain GMC_oxred_N PF00732.19 GAM43310.1 - 5.5e-26 91.6 0.0 6.5e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAM43310.1 - 9.6e-05 21.6 1.1 0.00012 21.2 1.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 GAM43310.1 - 0.0027 17.4 1.5 0.017 14.7 2.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAM43310.1 - 0.0036 16.6 1.5 0.0039 16.5 0.3 1.5 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 GAM43310.1 - 0.018 13.9 0.3 0.024 13.5 0.3 1.1 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 GAM43310.1 - 0.041 12.9 1.4 0.1 11.7 1.6 1.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 GAM43310.1 - 0.062 13.5 1.2 0.084 13.1 0.5 1.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GAM43310.1 - 4.2 6.6 5.2 24 4.1 3.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Glyco_hyd_65N_2 PF14498.6 GAM43312.1 - 5.5e-55 186.8 0.2 7.8e-55 186.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_43 PF04616.14 GAM43313.1 - 2.2e-36 125.7 5.2 2.2e-36 125.7 5.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 GAM43313.1 - 1.3e-27 96.9 0.0 1.9e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF3821 PF12863.7 GAM43313.1 - 6.4 6.6 9.8 1.4 8.8 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3821) p450 PF00067.22 GAM43315.1 - 8.4e-56 189.6 0.0 3.5e-54 184.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 COesterase PF00135.28 GAM43316.1 - 5.8e-64 216.8 0.0 8.4e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Aminotran_5 PF00266.19 GAM43316.1 - 5.1e-16 58.6 0.0 1.8e-15 56.8 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Abhydrolase_3 PF07859.13 GAM43316.1 - 0.0003 20.7 0.0 0.0012 18.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Cys_Met_Meta_PP PF01053.20 GAM43316.1 - 0.006 15.2 0.0 0.011 14.2 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAM43316.1 - 0.0077 15.4 0.0 0.042 13.0 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAM43316.1 - 0.058 12.7 0.3 0.36 10.1 0.3 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Sugar_tr PF00083.24 GAM43318.1 - 1.1e-91 308.0 28.0 1.4e-91 307.7 28.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM43318.1 - 3.2e-14 52.6 52.3 7.5e-10 38.3 38.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM43319.1 - 9.6e-08 31.4 0.0 9.6e-08 31.4 0.0 2.5 4 0 0 4 4 4 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM43319.1 - 2.6e-07 30.7 13.0 6.1e-07 29.5 13.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DS PF01916.17 GAM43319.1 - 0.024 13.9 0.0 0.058 12.6 0.0 1.6 1 0 0 1 1 1 0 Deoxyhypusine synthase NmrA PF05368.13 GAM43320.1 - 6.5e-31 107.7 0.0 1.5e-30 106.5 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM43320.1 - 5.4e-08 32.9 0.0 7.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAM43320.1 - 7.4e-05 22.3 0.0 0.00016 21.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM43320.1 - 0.038 13.4 0.0 0.63 9.4 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 GAM43321.1 - 1.4e-35 122.9 27.6 2.1e-35 122.3 27.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3474 PF11960.8 GAM43322.1 - 0.018 15.2 0.3 0.1 12.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Velvet PF11754.8 GAM43324.1 - 2.4e-95 319.2 0.0 3e-95 318.9 0.0 1.0 1 0 0 1 1 1 1 Velvet factor Big_3 PF07523.12 GAM43325.1 - 1.3e-06 28.6 1.4 2.6e-06 27.6 1.4 1.6 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) Glyco_hydro_43 PF04616.14 GAM43325.1 - 0.0012 18.3 0.5 0.0024 17.3 0.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 BUD22 PF09073.10 GAM43326.1 - 0.037 13.4 14.5 0.044 13.1 14.5 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 GAM43326.1 - 2.5 6.1 15.2 3.8 5.5 15.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi Acetyltransf_3 PF13302.7 GAM43327.1 - 1.4e-28 100.3 0.0 1.6e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM43327.1 - 6.4e-08 32.8 0.0 1.3e-06 28.7 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 GAM43327.1 - 0.022 14.9 0.0 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 GAM43327.1 - 0.18 11.5 0.1 1.6 8.4 0.0 2.2 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain BTB PF00651.31 GAM43328.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain FAD_binding_3 PF01494.19 GAM43330.1 - 3.9e-13 49.4 0.4 9.3e-13 48.1 0.4 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM43330.1 - 0.00017 21.8 0.0 0.00043 20.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM43330.1 - 0.0018 17.9 0.6 0.0052 16.4 0.1 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM43330.1 - 0.0033 16.7 0.2 0.083 12.1 0.1 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM43330.1 - 0.0044 15.9 0.4 0.038 12.9 0.1 2.0 1 1 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 GAM43330.1 - 0.0069 16.4 0.1 0.028 14.4 0.1 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAM43330.1 - 0.07 12.2 0.4 0.79 8.7 0.4 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein MCRA PF06100.11 GAM43330.1 - 0.075 11.8 0.1 0.14 10.9 0.1 1.4 2 0 0 2 2 2 0 MCRA family MFS_1 PF07690.16 GAM43331.1 - 3.7e-23 82.0 31.4 6.1e-23 81.3 31.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM43331.1 - 5.3e-07 29.3 16.1 0.0016 17.8 2.9 2.6 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB PS-DH PF14765.6 GAM43331.1 - 0.002 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase UPF0239 PF06783.11 GAM43331.1 - 0.13 12.4 0.2 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) AA_permease_2 PF13520.6 GAM43333.1 - 7.4e-61 206.3 54.4 9.3e-61 205.9 54.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM43333.1 - 2.9e-28 98.7 46.0 3.9e-28 98.3 46.0 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 GAM43334.1 - 1.5e-36 126.2 0.0 2.7e-36 125.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF3149 PF11346.8 GAM43334.1 - 1.8 8.3 4.9 4.1 7.1 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) adh_short_C2 PF13561.6 GAM43335.1 - 9.8e-40 136.6 0.0 1.1e-39 136.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM43335.1 - 2.3e-26 92.5 0.0 2.8e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase SnoaL_2 PF12680.7 GAM43336.1 - 4.2e-10 40.2 0.2 5.5e-10 39.8 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 GAM43336.1 - 0.031 14.7 0.1 0.044 14.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Aldedh PF00171.22 GAM43337.1 - 2.7e-130 435.0 0.0 3e-130 434.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Herpes_PAP PF03325.13 GAM43337.1 - 0.15 11.7 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus polymerase accessory protein adh_short PF00106.25 GAM43338.1 - 1.9e-35 122.1 0.0 2.8e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43338.1 - 2e-30 106.1 0.0 2.5e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 GAM43338.1 - 0.00067 19.6 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 GAM43338.1 - 0.001 19.0 0.0 0.0019 18.2 0.0 1.4 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 GAM43338.1 - 0.035 14.7 0.1 0.094 13.3 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 GAM43338.1 - 0.081 12.0 0.4 0.11 11.6 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 GAM43338.1 - 0.097 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 GAM43339.1 - 1.2e-22 80.2 0.0 2.2e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM43339.1 - 1.7e-21 76.1 2.9 1.7e-21 76.1 2.9 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM43339.1 - 3.9e-09 37.6 0.0 7.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 GAM43340.1 - 2.1e-30 105.7 0.3 2.8e-30 105.3 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_2 PF07883.11 GAM43341.1 - 2.2e-24 85.0 0.9 3.7e-16 58.6 0.3 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 GAM43341.1 - 0.0011 18.9 1.6 0.0081 16.1 0.3 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.12 GAM43341.1 - 0.0011 18.6 0.0 0.28 10.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) ARD PF03079.14 GAM43341.1 - 0.067 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 ARD/ARD' family FAA_hydrolase PF01557.18 GAM43342.1 - 1.3e-56 191.7 0.0 1.7e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TRI12 PF06609.13 GAM43343.1 - 3e-08 32.6 1.6 3.7e-08 32.2 1.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DSBA PF01323.20 GAM43344.1 - 4.5e-34 117.9 0.0 5.1e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 GAM43344.1 - 0.0018 18.5 0.3 0.0028 17.8 0.0 1.4 2 0 0 2 2 2 1 Thioredoxin NAD_binding_1 PF00175.21 GAM43345.1 - 1.1e-14 55.0 0.0 2.1e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 GAM43345.1 - 1.9e-09 38.0 0.1 4.4e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.24 GAM43345.1 - 1.7e-05 25.1 0.0 3.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAM43345.1 - 2.3e-05 24.6 0.0 8.2e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 GAM43345.1 - 0.00032 20.6 0.0 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Protoglobin Titin_Ig-rpts PF06582.12 GAM43346.1 - 0.075 13.0 0.2 0.17 11.9 0.2 1.6 1 0 0 1 1 1 0 Titin repeat Methyltransf_2 PF00891.18 GAM43349.1 - 6.5e-26 90.9 0.0 1.9e-25 89.4 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain CBM_2 PF00553.19 GAM43349.1 - 0.0012 19.2 0.2 0.003 17.8 0.2 1.6 1 0 0 1 1 1 1 Cellulose binding domain Methyltransf_31 PF13847.6 GAM43349.1 - 0.06 13.1 2.0 0.22 11.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Ysc84 PF04366.12 GAM43349.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Las17-binding protein actin regulator AAA_23 PF13476.6 GAM43349.1 - 3.7 8.0 9.3 8.2 6.9 9.3 1.6 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 GAM43350.1 - 3.1e-66 223.5 0.0 5.9e-66 222.6 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM43350.1 - 3.9e-18 65.8 0.0 1.3e-17 64.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM43350.1 - 2.7e-08 34.0 0.0 1.6e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit IMS_C PF11799.8 GAM43350.1 - 0.024 15.3 0.2 0.75 10.5 0.0 3.1 3 0 0 3 3 3 0 impB/mucB/samB family C-terminal domain TFIIF_beta PF02270.15 GAM43350.1 - 0.083 13.0 0.1 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 TFIIF, beta subunit HTH domain FtsL PF04999.13 GAM43350.1 - 0.098 12.7 3.7 0.33 11.0 3.7 1.9 1 0 0 1 1 1 0 Cell division protein FtsL Baculo_F PF12259.8 GAM43350.1 - 1.3 7.5 2.8 1.9 6.9 2.8 1.2 1 0 0 1 1 1 0 Baculovirus F protein AAA_11 PF13086.6 GAM43350.1 - 1.5 8.5 0.0 1.5 8.5 0.0 4.1 3 1 0 3 3 3 0 AAA domain Pkinase PF00069.25 GAM43351.1 - 2.1e-50 171.5 0.2 2.4e-49 168.1 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM43351.1 - 2.4e-23 82.7 0.0 5.4e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM43351.1 - 0.00023 21.2 3.7 0.0004 20.4 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAM43351.1 - 0.0033 17.1 0.4 0.017 14.8 0.4 2.0 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 GAM43351.1 - 0.19 11.3 4.0 0.36 10.4 0.2 2.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase eIF-3c_N PF05470.12 GAM43352.1 - 7.2e-177 589.3 17.2 8.3e-143 476.8 0.3 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 GAM43352.1 - 7.8e-13 48.9 3.6 3.6e-12 46.7 0.0 3.3 3 1 0 3 3 3 1 PCI domain DUF1385 PF07136.11 GAM43352.1 - 0.015 14.6 0.0 0.063 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) DUF3713 PF12506.8 GAM43352.1 - 2.9 8.2 8.4 4 7.8 2.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3713) SDA1 PF05285.12 GAM43352.1 - 4.5 6.6 28.0 7.3 5.9 28.0 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GAM43352.1 - 8.7 4.5 17.7 14 3.9 17.7 1.3 1 0 0 1 1 1 0 CDC45-like protein EAP30 PF04157.16 GAM43353.1 - 1.8e-72 243.4 0.0 2.1e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.7 GAM43353.1 - 0.098 12.6 0.0 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 MarR family HTH_27 PF13463.6 GAM43353.1 - 0.14 12.6 0.1 0.34 11.4 0.1 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain Ribosomal_L30_N PF08079.12 GAM43354.1 - 7e-27 93.5 16.5 1.1e-26 92.9 16.5 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 GAM43354.1 - 7.9e-18 64.1 2.1 7.9e-18 64.1 2.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e adh_short PF00106.25 GAM43356.1 - 2.4e-80 268.6 9.0 1.2e-42 145.6 1.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43356.1 - 5.5e-65 219.2 4.2 2e-35 122.4 0.3 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 GAM43356.1 - 1e-31 109.1 0.0 1.8e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 GAM43356.1 - 2.4e-25 89.5 2.7 1.4e-11 44.7 0.4 2.4 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 GAM43356.1 - 2.4e-05 23.7 1.4 0.0002 20.7 0.2 2.5 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PglL_A PF15864.5 GAM43356.1 - 2.4 8.0 8.0 5.5 6.8 1.0 2.4 2 0 0 2 2 2 0 Protein glycosylation ligase RhoGAP PF00620.27 GAM43357.1 - 1e-30 106.5 0.0 1.7e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain AIF-MLS PF14962.6 GAM43357.1 - 0.87 9.5 4.8 2.2 8.2 4.8 1.7 1 0 0 1 1 1 0 Mitochondria Localisation Sequence MFS_1 PF07690.16 GAM43359.1 - 1e-24 87.2 30.6 1e-24 87.2 30.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 GAM43359.1 - 0.099 10.9 7.8 0.26 9.5 7.8 1.7 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 GAM43360.1 - 2.3e-06 26.8 0.1 4.8e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain SBP_bac_11 PF13531.6 GAM43361.1 - 0.00016 21.5 0.0 0.00027 20.8 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Sugar_tr PF00083.24 GAM43362.1 - 1.4e-85 287.9 17.8 5.1e-79 266.3 14.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM43362.1 - 1.9e-27 96.2 24.7 3.1e-26 92.1 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAM43362.1 - 0.055 12.3 13.4 0.69 8.7 7.0 2.3 2 0 0 2 2 2 0 MFS_1 like family OATP PF03137.20 GAM43362.1 - 0.13 10.5 11.2 0.059 11.6 2.8 2.8 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF5311 PF17238.2 GAM43362.1 - 0.16 11.8 0.4 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5311) Phage_holin_3_2 PF04550.12 GAM43362.1 - 4.8 7.8 7.5 10 6.8 0.8 3.3 3 1 0 3 3 3 0 Phage holin family 2 Nramp PF01566.18 GAM43363.1 - 6.2e-92 308.3 22.1 1.7e-91 306.9 22.1 1.7 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein p450 PF00067.22 GAM43364.1 - 3.7e-06 26.0 0.0 4e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tho2 PF11262.8 GAM43364.1 - 0.1 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Fungal_trans PF04082.18 GAM43365.1 - 4.6e-07 29.1 0.1 8.8e-07 28.2 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Prenyltrans PF00432.21 GAM43366.1 - 2e-54 181.0 3.1 4.1e-11 42.4 0.0 5.8 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 GAM43366.1 - 0.002 17.3 0.0 0.042 12.9 0.0 2.5 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 GAM43366.1 - 0.0055 15.8 0.0 3.4 6.7 0.0 3.4 2 1 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain DHOR PF06537.11 GAM43366.1 - 0.074 11.7 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase zf-C2H2_jaz PF12171.8 GAM43367.1 - 0.03 14.6 0.8 0.08 13.3 0.8 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAM43367.1 - 1.4 9.4 4.7 7.2 7.2 4.7 2.2 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GAM43367.1 - 9.7 6.6 7.3 0.76 10.1 2.2 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) MutS_V PF00488.21 GAM43368.1 - 2.2e-74 249.6 0.2 5e-74 248.4 0.2 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAM43368.1 - 5.2e-38 131.2 2.0 1.3e-37 129.9 2.0 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 GAM43368.1 - 1.4e-29 102.6 0.0 3.5e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 GAM43368.1 - 1.4e-08 35.1 0.0 5.8e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 GAM43368.1 - 0.0017 18.7 0.0 0.022 15.1 0.0 2.8 2 0 0 2 2 2 1 MutS family domain IV DUF4911 PF16256.5 GAM43368.1 - 0.025 14.6 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4911) AROS PF15684.5 GAM43369.1 - 1.6 9.3 5.2 9.4 6.8 0.4 2.6 2 0 0 2 2 2 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 Abhydrolase_6 PF12697.7 GAM43370.1 - 1.9e-05 25.4 0.4 2.5e-05 25.0 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM43370.1 - 0.0017 18.0 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM43370.1 - 0.003 16.8 0.4 0.0051 16.1 0.4 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Fungal_trans PF04082.18 GAM43371.1 - 3.1e-06 26.4 0.4 7.7e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2235 PF09994.9 GAM43372.1 - 3.9e-77 259.4 0.0 4.9e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_6 PF12697.7 GAM43373.1 - 0.01 16.5 0.0 0.023 15.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM43373.1 - 0.083 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 GAM43373.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 GAM43373.1 - 0.14 11.3 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase HCV_NS4b PF01001.19 GAM43374.1 - 0.17 11.4 0.1 0.22 11.1 0.1 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4b PPARgamma_N PF12577.8 GAM43375.1 - 0.048 14.3 0.4 22 5.8 0.0 3.1 2 1 1 3 3 3 0 PPAR gamma N-terminal region Phage_tail_S PF05069.13 GAM43375.1 - 0.085 12.7 1.3 0.16 11.8 1.3 1.4 1 0 0 1 1 1 0 Phage virion morphogenesis family ADH_N_2 PF16884.5 GAM43376.1 - 4e-24 84.6 0.0 8e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 GAM43376.1 - 1.6e-19 70.1 0.1 2.7e-19 69.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM43376.1 - 4e-07 31.2 0.0 9e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 GAM43377.1 - 3.4e-42 144.1 0.1 5.6e-42 143.4 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43377.1 - 6.9e-39 133.8 0.1 2e-38 132.2 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM43377.1 - 3.3e-09 36.9 0.4 1.6e-08 34.7 0.1 2.0 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GAM43377.1 - 0.00028 20.1 0.1 0.00049 19.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 GAM43377.1 - 0.00028 20.9 0.0 0.0005 20.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 GAM43377.1 - 0.0058 16.7 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 GAM43377.1 - 0.041 13.3 0.2 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 GAM43377.1 - 0.054 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 GAM43377.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 GAM43377.1 - 0.062 12.8 0.3 0.22 10.9 0.3 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 GAM43377.1 - 0.072 13.5 0.1 0.31 11.5 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding HisG PF01634.18 GAM43378.1 - 6.8e-56 188.7 0.5 6.8e-56 188.7 0.5 1.4 2 0 0 2 2 2 1 ATP phosphoribosyltransferase HisG_C PF08029.11 GAM43378.1 - 8.6e-29 99.5 1.2 1.8e-28 98.5 1.2 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain Phage_sheath_1N PF17481.2 GAM43378.1 - 0.045 14.2 1.0 0.87 10.1 0.9 2.3 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain DUF1697 PF08002.11 GAM43378.1 - 0.065 13.7 0.1 0.11 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) Adaptin_binding PF10199.9 GAM43379.1 - 0.73 10.5 3.7 3.2 8.4 3.7 2.1 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Sugar_tr PF00083.24 GAM43380.1 - 4.5e-41 141.2 15.2 1.2e-26 93.6 1.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM43380.1 - 1.6e-16 60.2 30.7 1.3e-15 57.2 29.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily zf-CCHC_5 PF14787.6 GAM43381.1 - 0.00024 20.8 2.9 0.00057 19.5 2.9 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 GAM43381.1 - 0.002 18.1 1.1 0.0036 17.3 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle Tuberin PF03542.16 GAM43381.1 - 0.13 11.4 0.4 6.7 5.7 0.0 2.1 2 0 0 2 2 2 0 Tuberin RT_RNaseH PF17917.1 GAM43382.1 - 7.2e-37 125.9 0.5 1.6e-36 124.7 0.5 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAM43382.1 - 1.7e-32 112.7 0.1 2.8e-32 112.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GAM43382.1 - 1.2e-28 99.1 0.0 3.8e-28 97.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GAM43382.1 - 3.2e-22 78.4 0.0 7e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 GAM43382.1 - 6.9e-17 61.1 1.9 2e-16 59.6 1.0 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GAM43382.1 - 9.2e-15 54.9 0.0 1.9e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GAM43382.1 - 5.3e-06 26.5 0.0 2.2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 H2C2 zinc finger RVT_thumb PF06817.14 GAM43382.1 - 0.1 12.4 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase thumb domain SR-25 PF10500.9 GAM43383.1 - 0.52 9.9 10.5 0.97 9.0 10.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein S-methyl_trans PF02574.16 GAM43384.1 - 6.5e-62 209.8 0.0 7.4e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Peptidase_S58 PF03576.14 GAM43385.1 - 2.6e-114 381.8 0.2 3.2e-114 381.5 0.2 1.0 1 0 0 1 1 1 1 Peptidase family S58 CortBP2 PF09727.9 GAM43386.1 - 0.004 17.1 1.2 0.0075 16.2 1.2 1.4 1 0 0 1 1 1 1 Cortactin-binding protein-2 NPV_P10 PF05531.12 GAM43386.1 - 0.051 14.0 0.2 0.12 12.8 0.0 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 GAM43386.1 - 0.097 12.0 3.3 0.99 8.7 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DASH_Dad2 PF08654.10 GAM43386.1 - 0.33 11.4 0.0 0.33 11.4 0.0 2.3 4 0 0 4 4 4 0 DASH complex subunit Dad2 Myb_DNA-bind_3 PF12776.7 GAM43386.1 - 0.4 11.7 3.5 4.4 8.3 0.2 2.7 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain MIP-T3_C PF17749.1 GAM43386.1 - 0.82 9.6 4.9 0.37 10.7 0.6 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region p450 PF00067.22 GAM43387.1 - 2.8e-72 243.9 0.0 3.7e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 GAM43388.1 - 2.4e-47 161.7 48.2 2.2e-45 155.3 40.0 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 GAM43388.1 - 9.7e-24 83.8 32.0 9.7e-24 83.8 32.0 1.8 2 0 0 2 2 2 1 Amino acid permease Aminotran_1_2 PF00155.21 GAM43389.1 - 4.6e-62 210.3 0.0 6.1e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Pro_racemase PF05544.11 GAM43390.1 - 1.7e-127 425.0 0.2 1.9e-127 424.8 0.2 1.0 1 0 0 1 1 1 1 Proline racemase AAA PF00004.29 GAM43391.1 - 1.4e-16 61.1 0.0 2.7e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM43391.1 - 0.0022 18.3 0.2 0.0079 16.5 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 GAM43391.1 - 0.0038 17.2 0.1 0.01 15.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM43391.1 - 0.0069 16.8 0.2 0.033 14.6 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 GAM43391.1 - 0.028 14.8 0.0 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAM43391.1 - 0.047 13.4 0.1 0.088 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 GAM43391.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.26 GAM43391.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PNP_UDP_1 PF01048.20 GAM43392.1 - 4.1e-10 39.3 0.0 9.5e-10 38.1 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily SAS4 PF15460.6 GAM43394.1 - 2.2e-34 117.5 8.1 8.3e-34 115.6 8.1 2.1 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 UCH_C PF18031.1 GAM43394.1 - 0.0015 18.3 3.0 0.0057 16.5 3.0 2.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases PEHE PF15275.6 GAM43394.1 - 0.015 15.9 0.2 0.015 15.9 0.2 5.3 4 2 0 4 4 4 0 PEHE domain Oxidored_FMN PF00724.20 GAM43395.1 - 1e-74 251.8 0.0 1.5e-74 251.3 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 GAM43395.1 - 0.082 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Peptidase_M85 PF13678.6 GAM43397.1 - 0.044 13.4 0.1 0.07 12.7 0.1 1.2 1 0 0 1 1 1 0 NFkB-p65-degrading zinc protease Pollen_allerg_1 PF01357.21 GAM43398.1 - 1.9e-08 34.2 0.0 3.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Pollen allergen Glyco_hydro_3_C PF01915.22 GAM43399.1 - 1.4e-53 181.9 0.0 2.4e-53 181.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain MFS_1 PF07690.16 GAM43399.1 - 4.5e-44 150.8 56.7 4e-29 101.7 39.6 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Glyco_hydro_3 PF00933.21 GAM43399.1 - 1.4e-39 136.4 0.0 2.2e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Sugar_tr PF00083.24 GAM43399.1 - 2.2e-28 99.3 36.7 1.2e-26 93.6 12.8 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter Fn3-like PF14310.6 GAM43399.1 - 3.3e-21 75.2 1.2 1.3e-20 73.3 1.1 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 GAM43399.1 - 1e-06 28.7 0.0 2.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Fungal_trans PF04082.18 GAM43400.1 - 3.9e-10 39.2 0.0 7.3e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAM43400.1 - 3.1e-08 33.6 7.1 0.00088 19.6 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM43400.1 - 4.7e-07 30.1 6.3 0.011 16.6 0.4 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAM43400.1 - 5.6e-05 23.0 4.2 0.0033 17.4 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAM43400.1 - 0.0015 18.9 10.9 0.27 11.7 0.9 3.8 3 0 0 3 3 3 2 Zinc-finger double domain FAM76 PF16046.5 GAM43400.1 - 0.0084 15.5 0.7 0.014 14.8 0.7 1.2 1 0 0 1 1 1 1 FAM76 protein zf-C2H2_8 PF15909.5 GAM43400.1 - 0.091 13.1 0.9 0.2 11.9 0.9 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 GAM43400.1 - 0.11 12.1 1.8 9.4 6.0 0.3 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 GAM43400.1 - 0.24 11.9 3.8 0.26 11.8 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAM43400.1 - 0.34 11.2 5.6 6.9 7.1 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 GAM43400.1 - 0.78 10.2 5.0 60 4.2 5.0 2.7 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 GAM43400.1 - 1.2 9.2 4.5 13 5.9 0.8 2.6 1 1 1 2 2 2 0 BED zinc finger Bac_rhamnosid6H PF17389.2 GAM43401.1 - 2.9e-122 408.2 0.3 3.7e-122 407.8 0.3 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 GAM43401.1 - 8.8e-43 146.1 0.0 1.8e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 GAM43401.1 - 3.5e-29 100.8 0.0 1e-28 99.3 0.0 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 GAM43401.1 - 4.5e-20 71.2 0.2 1.2e-19 69.9 0.2 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Sugar_tr PF00083.24 GAM43402.1 - 4e-67 227.0 30.3 5.1e-67 226.7 30.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM43402.1 - 1.5e-21 76.8 39.4 1.5e-21 76.8 39.4 2.4 1 1 2 3 3 3 1 Major Facilitator Superfamily MFS_2 PF13347.6 GAM43402.1 - 0.0006 18.5 4.8 0.0006 18.5 4.8 3.9 2 2 1 3 3 3 3 MFS/sugar transport protein AT_hook PF02178.19 GAM43403.1 - 2.6e-11 42.0 46.5 0.15 12.0 1.5 8.5 7 0 0 7 7 7 7 AT hook motif DUF5005 PF16396.5 GAM43403.1 - 0.083 11.6 0.3 1.3 7.7 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5005) Macro PF01661.21 GAM43404.1 - 3.7e-11 43.1 0.1 1.9e-09 37.6 0.1 2.3 1 1 0 1 1 1 1 Macro domain DHDPS PF00701.22 GAM43405.1 - 3.1e-47 160.7 0.1 3.7e-47 160.4 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF218 PF02698.17 GAM43405.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 DUF218 domain MR_MLE_C PF13378.6 GAM43406.1 - 6e-53 179.7 0.1 8.1e-53 179.2 0.1 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 GAM43406.1 - 2.7e-19 69.5 0.0 5.1e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Queuosine_synth PF02547.15 GAM43406.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein adh_short PF00106.25 GAM43407.1 - 5e-46 156.6 0.5 1e-45 155.6 0.5 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43407.1 - 1.3e-45 155.8 0.2 3.9e-45 154.2 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM43407.1 - 2e-08 34.4 5.3 5.6e-07 29.6 1.1 2.9 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 GAM43407.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.11 GAM43407.1 - 0.012 15.3 0.1 0.14 11.8 0.0 2.3 2 1 0 2 2 2 0 Starch synthase catalytic domain DFP PF04127.15 GAM43407.1 - 0.017 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Exotox-A_cataly PF09009.10 GAM43407.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A catalytic Fungal_trans_2 PF11951.8 GAM43408.1 - 1.9e-16 59.9 0.1 3.8e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Med3 PF11593.8 GAM43408.1 - 0.14 11.3 1.3 0.22 10.7 0.1 1.8 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal HsbA PF12296.8 GAM43409.1 - 5.9e-21 75.1 11.3 5.9e-21 75.1 11.3 2.6 2 1 1 3 3 3 1 Hydrophobic surface binding protein A Fungal_trans PF04082.18 GAM43410.1 - 6.2e-19 68.1 0.1 1.3e-18 67.0 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S28e PF01200.18 GAM43411.1 - 3e-31 107.2 2.3 3.4e-31 107.0 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Dscam_C PF12355.8 GAM43412.1 - 0.92 10.5 3.6 3.4 8.7 0.2 2.3 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal CDC45 PF02724.14 GAM43413.1 - 0.28 9.4 2.3 0.38 9.0 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 GAM43413.1 - 0.33 10.2 8.2 0.48 9.7 8.2 1.2 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 GAM43413.1 - 0.57 8.2 6.6 0.023 12.8 0.9 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen AflR PF08493.10 GAM43414.1 - 0.083 12.4 6.8 0.12 11.9 6.8 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein Hexokinase_1 PF00349.21 GAM43415.1 - 3e-41 141.5 0.0 5.2e-41 140.7 0.0 1.4 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 GAM43415.1 - 2.3e-36 125.5 0.0 3.6e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Ank_2 PF12796.7 GAM43417.1 - 4.1e-56 187.5 0.8 7.8e-13 48.8 0.0 5.4 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM43417.1 - 2.4e-45 152.4 1.3 2.9e-07 30.9 0.0 9.2 3 3 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM43417.1 - 3.4e-39 128.3 0.4 0.0051 17.2 0.0 11.8 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 GAM43417.1 - 2.6e-33 113.6 1.6 1.2e-10 41.4 0.0 8.0 5 3 3 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 GAM43417.1 - 3.1e-29 100.1 3.8 0.076 13.5 0.0 10.9 11 0 0 11 11 11 7 Ankyrin repeat F-box PF00646.33 GAM43417.1 - 0.0016 18.3 0.5 0.004 17.0 0.5 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAM43417.1 - 0.0062 16.4 0.4 0.014 15.3 0.4 1.6 1 0 0 1 1 1 1 F-box-like VWA_3_C PF18571.1 GAM43417.1 - 0.073 13.0 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain Fungal_trans PF04082.18 GAM43418.1 - 1.2e-20 73.7 0.0 1.9e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM43418.1 - 3.3e-06 27.1 6.3 6.8e-06 26.1 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 GAM43419.1 - 6.1e-33 114.2 39.8 7.3e-33 113.9 39.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM43419.1 - 1.6e-07 30.9 22.8 1.8e-07 30.8 10.1 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB COesterase PF00135.28 GAM43420.1 - 1.2e-99 334.5 0.0 1.5e-99 334.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM43420.1 - 2.5e-08 34.1 0.1 1.8e-07 31.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PALP PF00291.25 GAM43421.1 - 2.3e-43 148.7 0.1 2.5e-43 148.6 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.18 GAM43421.1 - 0.094 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 LytB protein ABC2_membrane PF01061.24 GAM43422.1 - 2.5e-79 265.6 56.5 2.2e-45 154.7 24.4 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 GAM43422.1 - 2.7e-37 128.3 0.0 1.6e-17 64.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAM43422.1 - 6.9e-31 106.0 18.0 3e-30 103.9 0.0 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 GAM43422.1 - 1.1e-18 67.6 0.0 2.6e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 GAM43422.1 - 6e-07 30.0 0.1 0.00043 20.7 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAM43422.1 - 3.7e-06 26.9 0.2 0.00041 20.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 GAM43422.1 - 4.5e-05 23.4 0.2 1.5 8.5 0.1 3.5 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GAM43422.1 - 5.9e-05 22.7 0.2 0.00076 19.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 GAM43422.1 - 0.00019 22.0 0.0 0.023 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAM43422.1 - 0.002 17.9 1.5 0.027 14.2 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 GAM43422.1 - 0.0021 17.8 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAM43422.1 - 0.0026 18.0 0.2 1.1 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAM43422.1 - 0.0031 17.7 0.1 0.16 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 GAM43422.1 - 0.0038 16.8 0.3 1.2 8.7 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 GAM43422.1 - 0.0071 16.3 3.0 3.8 7.4 0.2 3.3 3 0 0 3 3 3 2 NACHT domain SMC_N PF02463.19 GAM43422.1 - 0.01 15.3 0.0 1.7 8.0 0.0 3.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 GAM43422.1 - 0.018 15.5 0.1 4.7 7.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 GAM43422.1 - 0.019 15.4 0.2 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF4209 PF13910.6 GAM43422.1 - 0.02 15.1 0.0 0.18 12.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4209) AAA_19 PF13245.6 GAM43422.1 - 0.041 14.2 0.3 3.2 8.1 0.1 3.0 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 GAM43422.1 - 0.058 13.1 0.1 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 GAM43422.1 - 0.08 13.2 0.0 2.8 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 GAM43422.1 - 0.1 11.7 38.3 0.067 12.3 22.7 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein dNK PF01712.19 GAM43422.1 - 0.13 12.1 1.1 12 5.7 0.0 2.6 3 0 0 3 3 2 0 Deoxynucleoside kinase Viral_helicase1 PF01443.18 GAM43422.1 - 0.14 11.9 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 GAM43422.1 - 0.15 11.3 0.2 9.5 5.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RuvB_N PF05496.12 GAM43422.1 - 0.24 11.1 0.4 16 5.2 0.1 2.6 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NifU_N PF01592.16 GAM43423.1 - 5.6e-42 142.9 0.1 7.2e-42 142.6 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Aldo_ket_red PF00248.21 GAM43424.1 - 3.3e-60 203.8 0.0 3.7e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 GAM43425.1 - 7.1e-06 26.0 4.4 1.3e-05 25.2 4.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAM43425.1 - 3.3e-05 22.9 0.6 6.1e-05 22.0 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FNIP_M PF14637.6 GAM43425.1 - 0.11 12.5 0.7 2 8.3 0.2 2.4 2 1 0 2 2 2 0 Folliculin-interacting protein middle domain ADH_zinc_N PF00107.26 GAM43426.1 - 2.8e-11 43.5 0.0 5.6e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase CENP-S PF15630.6 GAM43426.1 - 9.3e-10 38.8 0.0 2.6e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 CENP-S protein ADH_N PF08240.12 GAM43426.1 - 2.5e-05 24.1 0.1 4.7e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Scytalone_dh PF02982.14 GAM43427.1 - 1.8e-14 53.9 0.4 2.4e-14 53.5 0.4 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 GAM43427.1 - 2e-08 34.4 0.9 2.5e-08 34.1 0.9 1.1 1 0 0 1 1 1 1 SnoaL-like domain adh_short PF00106.25 GAM43428.1 - 2.2e-39 135.0 0.4 1.4e-37 129.1 0.4 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43428.1 - 1.1e-21 77.5 0.7 1.2e-19 70.8 0.7 2.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM43428.1 - 9.6e-09 35.4 0.2 1.7e-08 34.6 0.2 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAM43428.1 - 0.0019 17.5 0.1 0.0035 16.7 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Gamma_PGA_hydro PF05908.11 GAM43428.1 - 0.0029 17.1 1.7 0.0086 15.5 0.2 2.0 2 0 0 2 2 2 1 Poly-gamma-glutamate hydrolase 3HCDH_N PF02737.18 GAM43428.1 - 0.019 14.8 0.7 0.039 13.8 0.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 GAM43428.1 - 0.14 11.6 0.5 0.32 10.4 0.5 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TRI12 PF06609.13 GAM43429.1 - 4.5e-29 101.3 24.7 4.1e-27 94.9 16.1 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 GAM43429.1 - 2.7e-17 62.7 57.1 5.1e-17 61.8 49.3 3.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM43429.1 - 1.4e-09 37.4 13.0 1.4e-09 37.4 13.0 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter Pectate_lyase_3 PF12708.7 GAM43430.1 - 2.7e-54 184.3 27.8 7.9e-26 91.2 4.3 4.4 4 2 1 5 5 5 3 Pectate lyase superfamily protein End_N_terminal PF12218.8 GAM43430.1 - 0.013 15.2 1.0 0.086 12.5 0.0 2.6 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase UvdE PF03851.14 GAM43431.1 - 2.9e-111 371.1 0.0 4.7e-111 370.5 0.0 1.3 1 0 0 1 1 1 1 UV-endonuclease UvdE Anillin_N PF16018.5 GAM43431.1 - 5.6 7.6 9.2 2.3 8.9 3.9 3.0 3 0 0 3 3 3 0 Anillin N-terminus Glyco_hydro_61 PF03443.14 GAM43432.1 - 0.012 15.6 0.6 0.063 13.2 0.0 2.3 2 1 0 2 2 2 0 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 GAM43432.1 - 0.017 15.8 0.1 0.049 14.3 0.1 1.8 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading PGA2 PF07543.12 GAM43433.1 - 7.4e-21 74.6 22.2 5.9e-16 58.7 7.3 2.1 1 1 1 2 2 2 2 Protein trafficking PGA2 SpoIIIAH PF12685.7 GAM43433.1 - 0.0032 17.3 10.8 0.0053 16.6 10.8 1.3 1 0 0 1 1 1 1 SpoIIIAH-like protein V_ATPase_I PF01496.19 GAM43433.1 - 0.3 9.0 9.5 0.73 7.7 9.5 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 GAM43433.1 - 2.4 7.3 8.7 6 6.0 8.7 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter EphA2_TM PF14575.6 GAM43433.1 - 3.2 8.7 5.4 97 4.0 5.4 2.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LAP1C PF05609.12 GAM43433.1 - 5 6.1 19.4 6.5 5.7 19.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BNR_2 PF13088.6 GAM43434.1 - 8.5e-09 35.1 0.0 6.4e-08 32.2 0.0 2.1 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 GAM43434.1 - 6e-07 28.5 10.8 1 9.7 0.1 5.5 4 0 0 4 4 4 4 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 GAM43434.1 - 0.034 13.0 0.9 2.1 7.0 0.1 2.8 1 1 0 2 2 2 0 Sortilin, neurotensin receptor 3, Mo-co_dimer PF03404.16 GAM43434.1 - 0.041 13.9 0.4 12 5.9 0.0 3.6 4 0 0 4 4 4 0 Mo-co oxidoreductase dimerisation domain tRNA-synt_1g PF09334.11 GAM43435.1 - 6.7e-141 469.5 0.2 1.7e-79 267.4 0.2 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 GAM43435.1 - 6.9e-06 26.1 0.6 1.5e-05 25.0 0.6 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 GAM43435.1 - 6.1e-05 21.5 11.0 0.00013 20.3 0.0 3.3 4 0 0 4 4 4 2 tRNA synthetases class I (I, L, M and V) MFS_1 PF07690.16 GAM43438.1 - 2.8e-33 115.3 32.1 2.8e-33 115.3 32.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM43438.1 - 2.4e-14 53.1 1.1 2.4e-14 53.1 1.1 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter DUF4112 PF13430.6 GAM43438.1 - 1 9.7 5.9 0.31 11.3 0.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4112) Zn_clus PF00172.18 GAM43439.1 - 5.2e-09 36.1 2.8 5.2e-09 36.1 2.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2183 PF09949.9 GAM43440.1 - 2.7e-32 111.0 0.0 6.6e-32 109.8 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Sporozoite_P67 PF05642.11 GAM43442.1 - 0.0017 16.5 6.8 0.0027 15.9 6.8 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen eIF-3c_N PF05470.12 GAM43442.1 - 0.55 8.5 2.8 0.65 8.2 2.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_pol_phi PF04931.13 GAM43442.1 - 2.4 6.1 6.9 3.7 5.5 6.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 GAM43442.1 - 5.3 6.3 9.2 0.46 9.8 4.8 1.5 2 0 0 2 2 2 0 NOA36 protein MARVEL PF01284.23 GAM43443.1 - 1.4e-07 31.6 10.8 1.9e-07 31.2 10.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF805 PF05656.14 GAM43443.1 - 0.23 11.9 1.7 2.9 8.4 1.7 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF1158 PF06643.11 GAM43443.1 - 0.38 11.3 2.6 0.81 10.2 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1158) FMO-like PF00743.19 GAM43444.1 - 2.8e-13 49.2 0.0 7e-13 47.8 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAM43444.1 - 1.7e-11 43.9 0.0 1.2e-09 37.8 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAM43444.1 - 9.6e-11 41.5 0.0 2.3e-09 36.9 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM43444.1 - 2.3e-10 40.6 0.1 3.2e-08 33.7 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAM43444.1 - 2.5e-07 30.2 0.0 4.7e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM43444.1 - 7.4e-06 26.1 0.0 1.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM43444.1 - 7.8e-05 22.4 0.0 0.0048 16.5 0.1 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAM43444.1 - 0.00014 21.2 0.1 0.0011 18.2 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NIR_SIR PF01077.22 GAM43444.1 - 0.021 14.3 0.2 0.064 12.8 0.1 1.8 2 0 0 2 2 2 0 Nitrite and sulphite reductase 4Fe-4S domain FAD_binding_2 PF00890.24 GAM43444.1 - 0.051 12.6 0.0 4.3 6.3 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 GAM43444.1 - 0.099 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM43444.1 - 0.21 10.2 0.2 12 4.5 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein DUF1481 PF07356.12 GAM43445.1 - 0.0061 16.3 3.6 0.018 14.8 0.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1481) Sec1 PF00995.23 GAM43446.1 - 1.4e-110 371.3 0.0 1.9e-110 370.8 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Pkinase PF00069.25 GAM43446.1 - 1.4e-67 227.9 0.0 2.3e-67 227.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM43446.1 - 7e-33 114.0 0.0 1.3e-32 113.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM43446.1 - 0.00017 21.0 0.0 0.00038 19.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM43446.1 - 0.0057 16.0 0.0 0.017 14.5 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DGCR6 PF07324.11 GAM43446.1 - 0.069 12.8 0.7 0.38 10.3 0.4 2.3 3 0 0 3 3 3 0 DiGeorge syndrome critical region 6 (DGCR6) protein DUF1757 PF08560.10 GAM43447.1 - 0.0064 16.6 0.0 0.013 15.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1757) DUF3493 PF11998.8 GAM43447.1 - 0.071 13.3 1.4 2.6 8.3 0.0 2.7 3 1 0 3 3 3 0 Low psii accumulation1 / Rep27 Fungal_trans_2 PF11951.8 GAM43448.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fungus-induced PF10917.8 GAM43448.1 - 0.26 11.6 3.1 0.53 10.6 3.1 1.4 1 0 0 1 1 1 0 Fungus-induced protein EF-hand_7 PF13499.6 GAM43449.1 - 2.3e-23 82.4 4.9 9.2e-15 54.9 0.7 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 GAM43449.1 - 4.4e-23 79.1 10.2 1.2e-07 30.8 0.1 4.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GAM43449.1 - 1.7e-22 77.4 2.7 3.4e-06 26.5 0.1 5.6 5 1 1 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 GAM43449.1 - 8e-16 56.7 8.6 0.00015 21.1 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 GAM43449.1 - 9.7e-11 41.4 14.4 0.0012 18.6 0.7 5.1 3 2 1 4 4 4 3 EF-hand domain pair NAD_binding_10 PF13460.6 GAM43449.1 - 7.4e-09 35.8 0.1 1.8e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding EF-hand_4 PF12763.7 GAM43449.1 - 5.3e-08 32.7 5.8 0.011 15.7 0.2 4.3 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand 3Beta_HSD PF01073.19 GAM43449.1 - 1e-05 24.7 0.0 3e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 GAM43449.1 - 0.00027 21.0 0.0 0.00077 19.6 0.0 1.9 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 GAM43449.1 - 0.00042 19.9 0.0 0.0015 18.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family EF-hand_9 PF14658.6 GAM43449.1 - 0.003 17.8 0.8 0.047 14.0 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain NAD_binding_4 PF07993.12 GAM43449.1 - 0.0068 15.6 0.0 0.17 11.0 0.0 2.4 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 GAM43449.1 - 0.024 15.1 0.0 0.067 13.6 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SPARC_Ca_bdg PF10591.9 GAM43449.1 - 0.16 12.3 3.0 4.4 7.7 0.2 3.4 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EMP70 PF02990.16 GAM43450.1 - 7.9e-203 674.8 2.2 1.1e-202 674.4 2.2 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Sas10_Utp3 PF04000.15 GAM43451.1 - 1.6e-17 63.9 1.4 3e-17 63.0 0.3 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DNA_pol_phi PF04931.13 GAM43451.1 - 1.5 6.8 15.4 3.2 5.8 15.4 1.4 1 0 0 1 1 1 0 DNA polymerase phi Striatin PF08232.12 GAM43451.1 - 2.4 8.7 12.0 0.34 11.5 5.9 2.5 1 1 1 2 2 2 0 Striatin family NOA36 PF06524.12 GAM43451.1 - 5.5 6.2 10.1 11 5.3 10.1 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 GAM43451.1 - 6.2 7.3 11.5 14 6.1 11.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cerato-platanin PF07249.12 GAM43452.1 - 3.8e-37 127.0 2.2 4.5e-37 126.8 2.2 1.1 1 0 0 1 1 1 1 Cerato-platanin DUF5127 PF17168.4 GAM43453.1 - 1.7e-77 260.3 7.4 2.5e-77 259.7 7.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 GAM43453.1 - 3.2e-74 248.3 1.1 6.7e-74 247.3 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 GAM43453.1 - 5.1e-66 222.2 0.3 5.1e-66 222.2 0.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 GAM43453.1 - 2e-08 33.7 0.2 9.9e-08 31.4 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Phage_T4_gp36 PF03903.13 GAM43453.1 - 0.036 14.0 3.7 0.04 13.9 0.7 2.4 2 0 0 2 2 2 0 Phage T4 tail fibre APH PF01636.23 GAM43454.1 - 1.2e-18 67.9 0.0 1.5e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM43454.1 - 4.6e-06 26.4 0.0 6.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Lipase_GDSL_2 PF13472.6 GAM43455.1 - 5.3e-14 53.0 0.9 7e-14 52.6 0.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAM43455.1 - 6.4e-07 29.5 0.4 9.8e-07 28.9 0.4 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ELF PF03317.13 GAM43455.1 - 0.19 11.7 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 ELF protein GFO_IDH_MocA PF01408.22 GAM43456.1 - 1.3e-17 64.8 0.0 2.4e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAM43456.1 - 2.9e-17 62.7 0.3 6.4e-17 61.6 0.3 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain MFS_1 PF07690.16 GAM43457.1 - 3.6e-32 111.7 34.6 4.9e-32 111.2 33.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_42C PF08533.10 GAM43457.1 - 0.082 12.6 0.0 0.77 9.5 0.0 2.4 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Fungal_trans PF04082.18 GAM43458.1 - 2.5e-27 95.6 0.7 2.5e-27 95.6 0.7 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Pro-kuma_activ PF09286.11 GAM43459.1 - 1.3e-45 155.1 0.0 3.7e-45 153.7 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAM43459.1 - 1.8e-05 24.2 1.2 3.3e-05 23.3 1.2 1.3 1 0 0 1 1 1 1 Subtilase family DJ-1_PfpI PF01965.24 GAM43460.1 - 1.9e-09 37.6 0.0 6e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family Ntox1 PF15500.6 GAM43460.1 - 0.035 14.5 0.1 0.11 12.9 0.0 1.7 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 Fungal_trans PF04082.18 GAM43461.1 - 4.7e-21 75.0 1.8 8.7e-21 74.1 1.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM43461.1 - 1.1e-07 31.8 11.2 1.9e-07 31.1 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain THOC7 PF05615.13 GAM43461.1 - 0.0022 18.3 1.9 0.0042 17.4 0.1 2.3 3 0 0 3 3 3 1 Tho complex subunit 7 CCD48 PF15799.5 GAM43461.1 - 0.0043 15.4 0.6 0.013 13.9 0.7 1.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 48 AKNA PF12443.8 GAM43461.1 - 0.053 14.2 0.1 0.16 12.6 0.1 1.8 1 0 0 1 1 1 0 AT-hook-containing transcription factor Macoilin PF09726.9 GAM43461.1 - 0.11 11.0 1.6 0.16 10.5 1.6 1.1 1 0 0 1 1 1 0 Macoilin family Filament PF00038.21 GAM43461.1 - 0.18 11.4 1.7 0.14 11.7 0.2 1.5 2 0 0 2 2 2 0 Intermediate filament protein DivIC PF04977.15 GAM43461.1 - 0.22 11.3 2.5 0.3 10.9 0.5 2.2 2 0 0 2 2 2 0 Septum formation initiator HalX PF08663.10 GAM43461.1 - 0.62 10.4 2.3 1.1 9.6 0.9 2.1 2 0 0 2 2 2 0 HalX domain Tropomyosin PF00261.20 GAM43461.1 - 2.7 7.3 4.8 1.9 7.8 0.4 2.4 3 0 0 3 3 3 0 Tropomyosin Csm1_N PF18504.1 GAM43461.1 - 3.5 8.0 5.5 1 9.8 0.9 2.4 3 0 0 3 3 2 0 Csm1 N-terminal domain p450 PF00067.22 GAM43462.1 - 1.1e-29 103.6 0.0 1.2e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5486 PF17588.2 GAM43462.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5486) AbiJ_NTD5 PF18865.1 GAM43462.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 zf-C2H2 PF00096.26 GAM43463.1 - 6.1e-06 26.4 16.6 0.00023 21.4 0.8 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.18 GAM43463.1 - 2.2e-05 24.5 9.8 6e-05 23.1 9.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 GAM43463.1 - 2.2e-05 24.9 15.1 0.0023 18.6 0.7 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAM43463.1 - 0.085 13.2 0.2 0.085 13.2 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-CCHC_2 PF13696.6 GAM43463.1 - 0.099 12.5 10.5 0.47 10.3 2.2 2.8 2 0 0 2 2 2 0 Zinc knuckle zf-met PF12874.7 GAM43463.1 - 3 8.4 8.6 1.8 9.1 0.3 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 GAM43463.1 - 4.4 7.9 9.5 0.78 10.3 1.9 3.1 3 0 0 3 3 3 0 Zinc-finger double domain MFS_1 PF07690.16 GAM43464.1 - 2.8e-33 115.3 20.8 2.8e-33 115.3 20.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM43464.1 - 2.4e-12 46.5 6.9 2.4e-12 46.5 6.9 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAM43464.1 - 5.1e-07 28.5 5.3 9e-07 27.7 5.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 GAM43464.1 - 3.6e-05 22.2 0.5 0.00017 20.0 0.1 2.1 2 0 0 2 2 2 1 BT1 family DUF3040 PF11239.8 GAM43464.1 - 1 9.7 0.0 1 9.7 0.0 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF3040) PTR2 PF00854.21 GAM43464.1 - 1.5 7.5 10.6 0.44 9.3 5.7 2.3 2 1 1 3 3 3 0 POT family Mito_carr PF00153.27 GAM43466.1 - 5.8e-58 192.8 4.6 2e-19 69.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TRP PF06011.12 GAM43467.1 - 4.8e-37 127.7 25.4 3e-31 108.6 19.9 2.1 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 GAM43467.1 - 9.9e-19 68.1 0.0 1.6e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 ML-like domain KAP_NTPase PF07693.14 GAM43469.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Rnf-Nqr PF02508.14 GAM43469.1 - 2.2 8.2 11.7 6.7 6.7 11.7 1.7 1 1 0 1 1 1 0 Rnf-Nqr subunit, membrane protein Cys_Met_Meta_PP PF01053.20 GAM43470.1 - 6.6e-52 176.3 0.0 9.2e-52 175.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Methyltransf_23 PF13489.6 GAM43470.1 - 2.2e-13 50.4 0.0 4.3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM43470.1 - 8.1e-08 32.9 0.0 2.3e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM43470.1 - 1.1e-05 26.1 0.0 3.7e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM43470.1 - 0.0019 18.8 0.0 0.0045 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Aminotran_1_2 PF00155.21 GAM43470.1 - 0.0024 17.1 0.0 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Methyltransf_31 PF13847.6 GAM43470.1 - 0.011 15.5 0.0 0.039 13.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 GAM43470.1 - 0.051 12.9 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Aminotran_5 PF00266.19 GAM43470.1 - 0.051 12.5 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V MTS PF05175.14 GAM43470.1 - 0.18 11.3 0.0 0.46 10.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain RNB PF00773.19 GAM43472.1 - 2.6e-45 155.2 0.0 1.3e-42 146.3 0.0 2.5 1 1 0 1 1 1 1 RNB domain Tom6 PF17112.5 GAM43473.1 - 0.1 12.1 0.3 0.23 11.0 0.3 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal RNA_pol_Rpb2_6 PF00562.28 GAM43474.1 - 4.6e-123 411.1 0.0 7e-123 410.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAM43474.1 - 9.6e-57 191.8 0.0 2e-56 190.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 GAM43474.1 - 2.3e-46 157.9 0.0 6e-46 156.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 CTNNBL PF08216.11 GAM43474.1 - 8.2e-39 132.0 0.1 2.3e-38 130.5 0.1 1.8 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear RNA_pol_Rpb2_7 PF04560.20 GAM43474.1 - 9.8e-33 112.4 0.0 2.4e-32 111.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 GAM43474.1 - 1.7e-25 89.0 0.1 5e-25 87.5 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 GAM43474.1 - 2.2e-24 85.5 0.8 7.4e-24 83.8 0.8 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 GAM43474.1 - 3.8e-21 75.4 0.2 1.3e-20 73.6 0.2 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Arm PF00514.23 GAM43474.1 - 0.0017 18.3 0.0 0.2 11.8 0.0 3.0 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Mo25 PF08569.11 GAM43474.1 - 0.04 13.3 0.3 0.097 12.0 0.3 1.7 1 0 0 1 1 1 0 Mo25-like PHTB1_C PF14728.6 GAM43474.1 - 0.16 11.1 1.5 0.3 10.1 1.5 1.4 1 0 0 1 1 1 0 PTHB1 C-terminus AMPK1_CBM PF16561.5 GAM43475.1 - 0.00011 22.4 0.0 0.00018 21.6 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase SPX PF03105.19 GAM43475.1 - 1 9.2 6.6 1.2 9.0 6.6 1.1 1 0 0 1 1 1 0 SPX domain Beta-lactamase PF00144.24 GAM43476.1 - 9.9e-49 166.4 0.2 1.9e-48 165.4 0.0 1.5 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 GAM43476.1 - 2.4e-13 50.4 0.0 4.5e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Nre_N PF04894.12 GAM43476.1 - 0.022 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal Nre, N-terminal CAC1F_C PF16885.5 GAM43476.1 - 0.062 13.0 1.5 0.1 12.3 1.5 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Presenilin PF01080.17 GAM43476.1 - 0.23 10.2 1.7 0.29 9.9 1.7 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 GAM43476.1 - 0.35 10.1 0.8 0.5 9.5 0.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.16 GAM43476.1 - 4.3 6.8 6.1 6.6 6.2 6.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Nucleopor_Nup85 PF07575.13 GAM43477.1 - 4.8e-26 91.5 0.0 1.7e-24 86.4 0.0 2.2 1 1 0 1 1 1 1 Nup85 Nucleoporin SDA1 PF05285.12 GAM43477.1 - 0.004 16.6 16.1 0.0075 15.7 16.1 1.4 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GAM43477.1 - 0.16 10.1 19.7 0.26 9.4 19.7 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 GAM43477.1 - 1.1 7.7 21.0 1.9 7.0 21.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 GAM43477.1 - 1.4 8.2 17.6 2.4 7.4 17.6 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GAM43477.1 - 8.7 4.5 15.9 13 3.9 15.9 1.1 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 GAM43478.1 - 2.2e-43 148.6 46.3 4.8e-43 147.4 46.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM43478.1 - 3.3e-14 52.3 25.4 4.2e-14 51.9 25.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SPC25 PF06703.11 GAM43478.1 - 0.63 9.8 3.0 0.62 9.8 0.4 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Pox_A14 PF05767.12 GAM43478.1 - 1.2 9.4 5.5 0.49 10.6 0.1 2.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Sugar_tr PF00083.24 GAM43479.1 - 1.1e-129 433.2 22.4 1.3e-129 433.0 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM43479.1 - 1.6e-25 89.8 58.4 2.8e-24 85.7 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5357 PF17310.2 GAM43479.1 - 0.071 11.7 9.6 1.4 7.4 4.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5357) ADIP PF11559.8 GAM43480.1 - 2.3e-43 147.9 14.5 2.3e-43 147.9 14.5 2.5 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 GAM43480.1 - 0.00081 19.0 13.4 0.00081 19.0 13.4 2.4 2 0 0 2 2 2 1 Golgin subfamily A member 5 SOGA PF11365.8 GAM43480.1 - 0.012 16.7 4.3 0.012 16.7 4.3 3.6 4 0 0 4 4 4 0 Protein SOGA RepA_C PF04796.12 GAM43480.1 - 0.096 12.7 0.8 0.3 11.1 0.8 1.9 1 0 0 1 1 1 0 Plasmid encoded RepA protein TTRAP PF14203.6 GAM43480.1 - 0.24 11.4 1.4 1.7 8.7 0.1 2.7 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein FAP206 PF12018.8 GAM43480.1 - 0.29 10.6 7.3 0.76 9.2 7.3 1.7 1 0 0 1 1 1 0 Domain of unknown function Rx_N PF18052.1 GAM43480.1 - 1.3 9.3 9.4 3.6 7.9 2.4 3.5 2 1 1 3 3 3 0 Rx N-terminal domain FlaC_arch PF05377.11 GAM43480.1 - 6.3 7.3 11.6 1.2 9.6 1.3 3.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 GAM43480.1 - 6.5 5.5 22.7 0.023 13.6 11.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein KxDL PF10241.9 GAM43480.1 - 8 6.8 13.5 10 6.5 9.9 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein F-box PF00646.33 GAM43481.1 - 1.8e-10 40.5 0.6 6.2e-10 38.7 0.6 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAM43481.1 - 2.9e-10 39.9 0.7 6.2e-10 38.8 0.7 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GAM43481.1 - 0.00014 22.1 15.0 0.77 10.3 0.2 7.1 3 2 1 5 5 5 1 Leucine Rich repeats (2 copies) TPR_12 PF13424.6 GAM43481.1 - 0.0029 17.8 3.0 0.014 15.6 0.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM43481.1 - 0.011 15.4 0.3 0.029 14.0 0.3 1.7 1 0 0 1 1 1 0 TPR repeat PPR PF01535.20 GAM43481.1 - 0.021 15.0 1.4 16 6.0 0.0 3.4 3 0 0 3 3 3 0 PPR repeat TPR_2 PF07719.17 GAM43481.1 - 0.025 14.7 7.7 0.28 11.4 0.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 GAM43481.1 - 0.037 14.5 2.6 1.1 9.7 0.6 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain REF PF05755.12 GAM43481.1 - 0.08 12.8 0.2 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) TPR_14 PF13428.6 GAM43481.1 - 0.091 13.6 0.8 7.4 7.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM43481.1 - 0.099 13.2 4.6 10 6.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM43481.1 - 0.13 12.2 6.5 1.8 8.5 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAM43481.1 - 0.14 12.8 2.3 0.86 10.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM43481.1 - 0.6 10.4 3.6 5.3 7.4 0.1 2.5 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 IDO PF01231.18 GAM43482.1 - 3.4e-37 128.3 0.0 4.5e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase PET117 PF15786.5 GAM43483.1 - 6.3e-26 90.4 1.9 7.2e-26 90.3 1.9 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF3824 PF12868.7 GAM43483.1 - 0.069 13.8 0.6 0.077 13.7 0.6 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) V-ATPase_G PF03179.15 GAM43484.1 - 3.7e-33 114.2 17.5 4.3e-33 114.0 17.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 GAM43484.1 - 0.017 15.2 11.8 0.017 15.2 11.8 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 GAM43484.1 - 0.031 14.7 15.6 0.045 14.2 15.6 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF3584 PF12128.8 GAM43484.1 - 0.044 11.3 10.5 0.044 11.3 10.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3552 PF12072.8 GAM43484.1 - 0.07 12.5 21.6 0.047 13.1 17.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF1834 PF08873.11 GAM43484.1 - 0.12 12.1 0.8 0.15 11.8 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) DUF2229 PF09989.9 GAM43484.1 - 0.12 12.0 3.8 0.14 11.8 3.8 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF2203 PF09969.9 GAM43484.1 - 0.15 12.8 5.8 0.21 12.3 5.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) V_ATPase_I PF01496.19 GAM43484.1 - 0.5 8.2 7.4 0.59 8.0 7.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATP11 PF06644.11 GAM43484.1 - 0.67 9.7 9.0 0.79 9.5 9.0 1.0 1 0 0 1 1 1 0 ATP11 protein DUF4337 PF14235.6 GAM43484.1 - 6.2 6.9 10.4 9.4 6.3 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF883 PF05957.13 GAM43484.1 - 7.6 7.2 10.7 75 4.0 10.7 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.6 GAM43484.1 - 8.6 5.6 9.8 9.6 5.5 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Arrestin_N PF00339.29 GAM43485.1 - 1.1e-13 51.5 0.3 1.1e-13 51.5 0.3 3.7 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 GAM43485.1 - 0.64 9.4 0.0 0.64 9.4 0.0 3.1 3 0 0 3 3 3 0 Bul1 C terminus Pyr_redox_2 PF07992.14 GAM43486.1 - 8.5e-48 163.1 0.1 1.1e-47 162.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 GAM43486.1 - 2e-16 59.7 0.0 5.8e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 GAM43486.1 - 1.6e-14 54.2 0.9 1.7e-12 47.7 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 GAM43486.1 - 1e-08 35.1 0.0 5.8e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.6 GAM43486.1 - 7e-06 26.5 0.0 2.9e-05 24.5 0.0 2.1 3 0 0 3 3 3 1 Reductase C-terminal NAD_binding_9 PF13454.6 GAM43486.1 - 0.0084 16.1 0.0 5.2 7.0 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 GAM43486.1 - 0.011 14.9 0.1 2.4 7.2 0.0 2.4 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 GAM43486.1 - 0.013 15.0 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Kelch_1 PF01344.25 GAM43486.1 - 0.037 13.6 0.2 4.9 6.8 0.0 3.2 3 0 0 3 3 3 0 Kelch motif TrkA_N PF02254.18 GAM43486.1 - 0.12 12.7 0.2 1.4 9.2 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain Tegument_dsDNA PF12818.7 GAM43487.1 - 0.011 14.9 1.3 2.2 7.4 0.7 2.3 2 0 0 2 2 2 0 dsDNA viral tegument protein Bap31_Bap29_C PF18035.1 GAM43487.1 - 0.023 14.7 2.5 0.58 10.2 0.0 3.1 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Phage_GP20 PF06810.11 GAM43487.1 - 4.1 7.2 23.7 0.17 11.7 6.0 3.4 2 1 2 4 4 4 0 Phage minor structural protein GP20 BRE1 PF08647.11 GAM43487.1 - 7.1 6.8 28.2 0.063 13.4 12.4 3.4 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase TMPIT PF07851.13 GAM43487.1 - 7.8 5.6 16.4 3.1 6.9 6.2 2.5 1 1 1 2 2 2 0 TMPIT-like protein Dicty_REP PF05086.12 GAM43487.1 - 8.2 4.3 11.7 14 3.5 11.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CLTH PF10607.9 GAM43488.1 - 9.4e-30 103.5 0.0 1.7e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 GAM43488.1 - 3.1e-20 72.5 0.1 4.9e-20 71.8 0.1 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 GAM43488.1 - 0.00024 21.0 0.2 0.00087 19.2 0.2 2.1 1 0 0 1 1 1 1 LisH ADH_zinc_N PF00107.26 GAM43489.1 - 1.5e-18 67.0 0.0 2.3e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 GAM43489.1 - 5.3e-10 39.2 0.0 2.5e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 GAM43489.1 - 7.8e-06 27.0 0.0 1.4e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase INO80_Ies4 PF08193.11 GAM43490.1 - 5.8e-54 183.6 21.2 5.8e-54 183.6 21.2 1.7 1 1 1 2 2 2 1 INO80 complex subunit Ies4 DnaJ PF00226.31 GAM43491.1 - 1.2e-14 54.1 0.0 2.1e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain EF-hand_like PF09279.11 GAM43491.1 - 0.15 12.6 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like RPA43_OB PF17875.1 GAM43492.1 - 2.1e-39 135.0 0.0 2.1e-39 135.0 0.0 2.9 3 0 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 GAM43492.1 - 0.00022 21.5 0.0 0.00059 20.1 0.0 1.8 1 1 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 AP3D1 PF06375.11 GAM43492.1 - 2 8.6 14.7 3.8 7.7 5.1 2.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Fungal_trans_2 PF11951.8 GAM43493.1 - 1.2e-06 27.6 1.6 2.3e-06 26.7 1.6 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM43493.1 - 6.8e-05 22.9 10.0 0.00013 22.0 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF755 PF05501.11 GAM43493.1 - 3.1 8.1 9.0 7.9 6.8 9.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF755) MFS_1 PF07690.16 GAM43494.1 - 1.5e-30 106.3 29.3 2.4e-30 105.7 29.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_16 PF10294.9 GAM43494.1 - 2.8e-18 66.3 0.0 4.6e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MFS_4 PF06779.14 GAM43494.1 - 1.9e-05 24.2 10.9 7.5e-05 22.2 1.5 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MTS PF05175.14 GAM43494.1 - 0.0069 16.0 0.0 0.018 14.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Ribosomal_S24e PF01282.19 GAM43495.1 - 1.3e-35 121.1 0.4 2.2e-35 120.4 0.1 1.5 1 1 1 2 2 2 1 Ribosomal protein S24e RRXRR PF14239.6 GAM43495.1 - 0.0039 17.1 2.6 0.0049 16.8 2.5 1.2 1 1 0 1 1 1 1 RRXRR protein FAD_binding_4 PF01565.23 GAM43495.1 - 0.028 14.2 0.0 0.036 13.8 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain ArAE_2_N PF10337.9 GAM43496.1 - 1.4e-99 334.3 4.2 3.6e-98 329.7 0.6 2.3 2 0 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 GAM43496.1 - 3.8e-50 170.8 0.1 3.5e-49 167.7 0.1 2.3 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 GAM43496.1 - 5.3e-10 39.5 18.3 5.3e-10 39.5 18.3 3.5 3 1 0 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 GAM43496.1 - 0.0011 17.7 23.7 0.019 13.6 0.0 4.0 3 2 0 3 3 3 3 Fusaric acid resistance protein family ALMT PF11744.8 GAM43496.1 - 2.2 7.0 16.0 0.055 12.3 7.4 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter Amidohydro_2 PF04909.14 GAM43497.1 - 4.6e-42 144.8 0.1 5.4e-42 144.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase FtsJ PF01728.19 GAM43498.1 - 1.5e-07 31.7 0.0 4.3e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF2207 PF09972.9 GAM43498.1 - 0.32 9.7 1.4 0.44 9.2 0.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Shisa PF13908.6 GAM43498.1 - 0.46 10.7 8.0 2.7 8.2 0.0 2.9 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator WD40 PF00400.32 GAM43499.1 - 1.6e-42 142.7 11.1 2.5e-05 24.9 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM43499.1 - 9.4e-13 48.3 0.3 0.001 19.3 0.0 5.0 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM43499.1 - 0.01 15.2 0.0 7.2 5.8 0.1 3.4 2 1 2 4 4 4 0 WD40-like domain Nup160 PF11715.8 GAM43499.1 - 0.071 11.7 0.1 7.1 5.1 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAM43499.1 - 0.11 11.3 1.1 8 5.1 0.1 2.6 1 1 0 2 2 2 0 Nup133 N terminal like TRAPP PF04051.16 GAM43500.1 - 2.9e-29 101.7 0.0 3.3e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component RRM_1 PF00076.22 GAM43503.1 - 1.1e-44 150.1 0.0 2e-16 59.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM43503.1 - 0.00024 21.0 0.1 0.0039 17.2 0.0 2.8 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 GAM43503.1 - 0.0005 20.1 0.0 0.0032 17.5 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 GAM43503.1 - 0.00086 19.1 0.0 0.15 11.9 0.0 2.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 GAM43503.1 - 0.0035 17.4 0.1 0.13 12.4 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 GAM43503.1 - 0.031 13.9 0.0 0.18 11.4 0.0 2.2 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Statherin PF03875.13 GAM43503.1 - 7.2 6.8 7.2 23 5.2 7.2 1.9 1 0 0 1 1 1 0 Statherin TFB6 PF17110.5 GAM43504.1 - 3.3e-54 183.2 0.0 3.3e-54 183.2 0.0 1.4 2 0 0 2 2 2 1 Subunit 11 of the general transcription factor TFIIH TPR_12 PF13424.6 GAM43505.1 - 2.7e-08 34.0 2.8 0.00019 21.6 0.7 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM43505.1 - 0.00072 19.5 4.8 20 5.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM43505.1 - 0.006 17.1 0.1 0.014 15.9 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Fuseless PF15993.5 GAM43505.1 - 0.028 13.6 0.2 0.05 12.8 0.2 1.4 1 0 0 1 1 1 0 Fuseless TPR_20 PF14561.6 GAM43505.1 - 0.038 14.3 0.1 0.086 13.2 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAM43505.1 - 0.042 14.5 0.1 0.12 13.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM43505.1 - 0.054 13.7 5.7 3.1 8.2 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Gal_mutarotas_2 PF13802.6 GAM43505.1 - 0.091 13.1 0.0 0.39 11.1 0.0 2.1 1 0 0 1 1 1 0 Galactose mutarotase-like DUF3433 PF11915.8 GAM43505.1 - 0.43 11.1 2.7 1 9.9 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) TPR_10 PF13374.6 GAM43505.1 - 1.5 8.8 3.6 11 6.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Golgin_A5 PF09787.9 GAM43506.1 - 0.28 10.6 2.1 7.9 5.8 0.1 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 RRM_Rrp7 PF17799.1 GAM43507.1 - 3.1e-29 101.8 0.0 4.9e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 GAM43507.1 - 3.3e-29 101.4 3.4 3.3e-29 101.4 3.4 2.0 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain MFS_1 PF07690.16 GAM43508.1 - 1.1e-29 103.5 15.2 1.4e-29 103.1 15.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM43508.1 - 3.2e-09 36.6 3.3 4.6e-09 36.1 3.3 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF2929 PF11151.8 GAM43508.1 - 0.017 15.4 0.2 0.18 12.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) Rad51 PF08423.11 GAM43509.1 - 2.8e-112 374.1 0.0 3.5e-112 373.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 GAM43509.1 - 2e-11 43.9 0.0 2.7e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 GAM43509.1 - 1.4e-08 35.2 0.8 3.1e-08 34.1 0.2 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 GAM43509.1 - 2.5e-07 30.3 0.0 6.2e-07 29.0 0.0 1.8 2 1 0 2 2 2 1 KaiC AAA_25 PF13481.6 GAM43509.1 - 1.1e-05 25.1 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAM43509.1 - 0.01 15.6 0.0 0.04 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.15 GAM43509.1 - 0.019 14.3 0.1 0.7 9.2 0.1 2.2 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.11 GAM43509.1 - 0.081 12.1 0.2 1.2 8.2 0.0 2.2 2 1 0 2 2 2 0 PAXNEB protein Phage_HK97_TLTM PF06120.11 GAM43509.1 - 0.15 11.3 0.0 11 5.1 0.0 2.2 2 0 0 2 2 2 0 Tail length tape measure protein zf-CCHC PF00098.23 GAM43510.1 - 2.1e-44 147.7 58.3 2.4e-07 30.5 0.9 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 GAM43510.1 - 2.7e-09 36.6 41.8 0.19 11.5 1.1 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 GAM43510.1 - 0.00045 20.1 47.7 0.013 15.5 0.6 6.9 3 2 2 5 5 5 4 Zinc knuckle zf-CCHC_5 PF14787.6 GAM43510.1 - 0.001 18.7 44.7 0.021 14.5 0.9 7.1 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GAM43510.1 - 0.056 13.3 1.0 0.056 13.3 1.0 7.1 7 0 0 7 7 7 0 Zinc knuckle DUF4366 PF14283.6 GAM43510.1 - 0.93 9.5 3.2 1.8 8.6 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) UDPGP PF01704.18 GAM43511.1 - 4e-50 170.7 0.0 1.3e-49 169.0 0.0 1.7 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pro_isomerase PF00160.21 GAM43512.1 - 1.1e-20 74.6 0.0 2.3e-20 73.5 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 GAM43512.1 - 1.6e-15 56.7 0.1 4.8e-15 55.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_47 PF01532.20 GAM43514.1 - 7.5e-119 397.6 0.0 1e-118 397.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Abhydrolase_1 PF00561.20 GAM43515.1 - 2.5e-16 60.1 0.2 1.9e-09 37.6 0.2 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM43515.1 - 6.2e-13 49.9 0.0 7.8e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM43515.1 - 4.2e-11 42.6 0.0 2.2e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAM43515.1 - 4.6e-05 23.0 0.3 0.094 12.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 GAM43515.1 - 0.0049 17.0 0.0 0.0086 16.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.18 GAM43515.1 - 0.0049 16.4 0.1 1.5 8.3 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 GAM43515.1 - 0.08 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AIG2_2 PF13772.6 GAM43516.1 - 0.00019 21.7 0.1 0.093 13.1 0.0 2.8 3 0 0 3 3 3 2 AIG2-like family GGACT PF06094.12 GAM43516.1 - 0.00029 21.4 0.2 0.00085 19.9 0.2 1.8 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like GspH PF12019.8 GAM43516.1 - 0.043 14.2 0.1 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 Type II transport protein GspH LigB PF02900.18 GAM43517.1 - 9.2e-33 113.5 0.0 1.2e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short PF00106.25 GAM43518.1 - 4.5e-09 36.1 0.0 6.2e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43518.1 - 4.7e-09 36.2 0.0 5.8e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 GAM43518.1 - 0.006 16.2 0.1 0.0096 15.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAM43518.1 - 0.0087 15.5 0.0 0.035 13.6 0.0 1.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAM43518.1 - 0.014 14.5 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.18 GAM43518.1 - 0.032 14.1 0.1 0.05 13.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAM43518.1 - 0.078 13.2 0.2 0.67 10.2 0.2 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Phage_T4_gp36 PF03903.13 GAM43518.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Phage T4 tail fibre 2-Hacid_dh_C PF02826.19 GAM43518.1 - 0.21 10.9 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pribosyltran PF00156.27 GAM43519.1 - 5.7e-17 61.7 0.0 7.7e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAM43519.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Ribonuc_L-PSP PF01042.21 GAM43521.1 - 1.2e-37 128.6 0.0 1.5e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.18 GAM43522.1 - 8.5e-28 97.1 0.2 1.3e-27 96.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dak1 PF02733.17 GAM43523.1 - 2.8e-99 332.0 2.0 4.4e-99 331.3 2.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 GAM43523.1 - 6.8e-45 153.1 1.0 6.8e-45 153.1 1.0 1.8 2 0 0 2 2 2 1 DAK2 domain NAD_binding_4 PF07993.12 GAM43524.1 - 1.2e-36 126.2 0.0 1.9e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAM43524.1 - 1.8e-31 109.2 0.0 2.8e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAM43524.1 - 5.5e-13 48.9 0.0 1.1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAM43524.1 - 4.2e-08 33.4 0.1 1e-07 32.2 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 GAM43524.1 - 0.025 14.0 0.1 0.13 11.7 0.0 2.1 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase SNF2_N PF00176.23 GAM43525.1 - 1.3e-65 221.4 0.6 2.4e-65 220.5 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM43525.1 - 4.6e-20 72.0 0.0 1.7e-19 70.2 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM43525.1 - 1.7e-09 37.9 0.0 5.4e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 GAM43525.1 - 1.2e-07 32.0 9.3 1.2e-07 32.0 9.3 3.0 2 0 0 2 2 2 1 HSA DEAD PF00270.29 GAM43525.1 - 0.00051 19.9 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Membr_traf_MHD PF10540.9 GAM43526.1 - 1e-19 71.2 0.5 8.5e-10 39.0 0.4 2.9 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 GAM43526.1 - 4.8e-13 49.3 0.0 9.5e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain NDUF_B8 PF05821.11 GAM43526.1 - 2.1e-09 37.5 0.0 5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF810 PF05664.11 GAM43526.1 - 2.1e-08 33.2 1.7 1.8e-07 30.1 0.3 2.6 3 0 0 3 3 3 1 Plant family of unknown function (DUF810) ATP12 PF07542.11 GAM43527.1 - 1.5e-43 147.9 2.2 1.8e-43 147.7 1.0 1.7 2 0 0 2 2 2 1 ATP12 chaperone protein Oxysterol_BP PF01237.18 GAM43528.1 - 5.4e-128 427.0 0.1 1.2e-127 425.8 0.0 1.5 2 0 0 2 2 2 1 Oxysterol-binding protein Glyco_tranf_2_3 PF13641.6 GAM43528.1 - 2.4e-29 102.8 0.1 4.1e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 zf-Mss51 PF13824.6 GAM43528.1 - 1.6e-28 98.6 5.3 5.4e-28 96.9 5.3 2.0 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Ank_2 PF12796.7 GAM43528.1 - 3.3e-15 56.4 0.0 5.9e-08 33.2 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM43528.1 - 1.1e-13 51.1 0.2 2.9e-09 37.0 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM43528.1 - 8e-11 42.3 0.1 2.8e-05 24.6 0.1 4.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM43528.1 - 1e-10 41.5 0.1 0.011 16.2 0.0 3.9 4 0 0 4 4 3 2 Ankyrin repeat PH PF00169.29 GAM43528.1 - 2e-10 41.1 0.4 5.4e-10 39.7 0.4 1.8 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 GAM43528.1 - 8.3e-09 35.0 0.0 0.031 14.8 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat PH_8 PF15409.6 GAM43528.1 - 1.5e-06 28.4 0.6 4.2e-06 27.0 0.6 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Glycos_transf_2 PF00535.26 GAM43528.1 - 4.4e-06 26.6 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAM43528.1 - 0.00011 21.8 0.0 0.00064 19.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 PH_11 PF15413.6 GAM43528.1 - 0.00054 20.4 1.7 0.00054 20.4 1.7 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain zf-MYND PF01753.18 GAM43528.1 - 0.0057 16.7 2.1 0.013 15.6 0.4 2.3 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 GAM43528.1 - 0.34 10.8 2.1 7.6 6.5 0.3 2.4 2 0 0 2 2 2 0 HIT zinc finger LLC1 PF14945.6 GAM43528.1 - 0.97 10.0 5.5 0.39 11.3 1.8 2.3 2 0 0 2 2 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Malic_M PF03949.15 GAM43531.1 - 3.9e-94 314.7 0.0 5.4e-94 314.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GAM43531.1 - 9.7e-32 110.2 0.1 8.8e-30 103.8 0.0 2.4 1 1 1 2 2 2 2 Malic enzyme, N-terminal domain GCHY-1 PF02649.14 GAM43531.1 - 0.016 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 bZIP_1 PF00170.21 GAM43532.1 - 1.8e-05 24.8 1.9 5.2e-05 23.3 1.9 1.7 1 0 0 1 1 1 1 bZIP transcription factor Na_Ca_ex PF01699.24 GAM43534.1 - 1.9e-38 131.8 48.0 1.3e-22 80.4 20.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YL1 PF05764.13 GAM43534.1 - 0.39 10.8 14.2 0.61 10.2 14.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Ras PF00071.22 GAM43535.1 - 7.5e-39 132.9 0.0 2.1e-38 131.4 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 GAM43535.1 - 3.5e-28 98.2 0.0 6.1e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM43535.1 - 1.1e-09 38.0 0.0 3.6e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM43535.1 - 9.3e-06 25.2 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAM43535.1 - 9.7e-05 22.0 0.0 0.00041 19.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM43535.1 - 0.00051 20.1 0.0 0.00088 19.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM43535.1 - 0.0019 18.1 0.0 0.058 13.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 GAM43535.1 - 0.0058 16.1 0.0 0.01 15.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 GAM43535.1 - 0.01 15.6 0.0 0.043 13.6 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 GAM43535.1 - 0.03 14.5 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM43535.1 - 0.033 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 GAM43535.1 - 0.048 13.6 0.0 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 GAM43535.1 - 0.059 13.8 0.1 0.13 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAM43535.1 - 0.078 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAM43535.1 - 0.086 12.8 0.0 0.32 11.0 0.0 1.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 GAM43535.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAM43535.1 - 0.15 12.6 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Adeno_IVa2 PF02456.15 GAM43535.1 - 0.21 10.3 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein PduV-EutP PF10662.9 GAM43535.1 - 0.22 11.3 0.0 0.88 9.3 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Glyco_hydro_3_C PF01915.22 GAM43536.1 - 4.8e-43 147.5 0.1 9.1e-43 146.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain ADH_N PF08240.12 GAM43536.1 - 1.1e-32 112.1 0.1 1.1e-32 112.1 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_3 PF00933.21 GAM43536.1 - 2.8e-32 112.4 0.0 5e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain ADH_zinc_N PF00107.26 GAM43536.1 - 5e-22 78.3 0.5 1.2e-21 77.0 0.5 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase WSC PF01822.19 GAM43536.1 - 3.7e-18 65.5 13.8 7.7e-18 64.5 13.8 1.6 1 0 0 1 1 1 1 WSC domain Glu_dehyd_C PF16912.5 GAM43536.1 - 2.2e-08 33.9 0.3 4.3e-08 32.9 0.3 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAM43536.1 - 0.00065 20.8 0.0 0.0021 19.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAM43536.1 - 0.0034 16.7 1.3 0.0083 15.4 1.3 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 GAM43536.1 - 0.042 13.1 0.0 0.13 11.5 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 GAM43536.1 - 0.059 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 GAM43536.1 - 0.081 13.6 0.1 0.39 11.5 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase domain BNR PF02012.20 GAM43537.1 - 0.096 12.7 6.1 6.5 7.2 0.4 3.7 3 0 0 3 3 3 0 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 GAM43537.1 - 0.2 10.4 0.1 1.4 7.6 0.0 2.0 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, FAD-oxidase_C PF02913.19 GAM43538.1 - 1.4e-56 191.9 0.1 1.9e-56 191.5 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAM43538.1 - 2.3e-38 131.1 0.0 3.8e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Clr5 PF14420.6 GAM43540.1 - 6.9e-19 67.8 0.8 3e-18 65.8 0.8 2.2 1 0 0 1 1 1 1 Clr5 domain RNA_pol_N PF01194.17 GAM43541.1 - 6.4e-31 106.4 1.2 7.7e-31 106.2 1.2 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.32 GAM43542.1 - 3.6e-05 24.4 1.6 0.096 13.6 0.0 5.7 6 0 0 6 6 6 1 WD domain, G-beta repeat Fer4_13 PF13370.6 GAM43543.1 - 0.27 11.8 2.6 9.9 6.8 0.3 3.8 3 2 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I PP2C PF00481.21 GAM43544.1 - 3.5e-21 76.0 0.0 1.3e-13 51.2 0.0 2.4 1 1 1 2 2 2 2 Protein phosphatase 2C Sugar_tr PF00083.24 GAM43545.1 - 2.4e-102 343.1 26.4 2.8e-102 342.9 26.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM43545.1 - 2.2e-23 82.8 31.1 4.8e-13 48.8 12.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM43545.1 - 0.00083 18.0 22.4 0.0063 15.1 2.8 2.9 2 2 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 GAM43545.1 - 3.8 5.7 11.8 0.15 10.3 0.8 2.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family adh_short_C2 PF13561.6 GAM43546.1 - 7.7e-27 94.3 0.1 9.4e-27 94.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM43546.1 - 2e-17 63.3 0.0 2.5e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM43546.1 - 0.00034 20.6 0.1 0.00052 20.0 0.1 1.3 1 0 0 1 1 1 1 KR domain PALP PF00291.25 GAM43546.1 - 0.0042 16.6 0.1 0.012 15.0 0.1 1.7 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme Oxidored_nitro PF00148.19 GAM43546.1 - 0.018 13.8 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase NAD_binding_7 PF13241.6 GAM43546.1 - 0.019 15.4 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 GAM43546.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DDE_1 PF03184.19 GAM43547.1 - 8.1e-15 54.9 0.0 2.6e-13 50.0 0.0 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 GAM43547.1 - 3.8e-05 23.6 0.0 0.00011 22.1 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain NACHT PF05729.12 GAM43548.1 - 3.1e-12 46.7 0.0 7.3e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 GAM43548.1 - 1.5e-08 34.1 0.0 3.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 GAM43548.1 - 0.00081 19.7 0.0 0.0025 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM43548.1 - 0.014 15.8 0.2 0.068 13.5 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 GAM43548.1 - 0.063 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA PF00004.29 GAM43548.1 - 0.092 13.2 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PNP_UDP_1 PF01048.20 GAM43548.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphorylase superfamily AAA_18 PF13238.6 GAM43548.1 - 0.15 12.6 0.0 0.44 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GAM43548.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 GAM43548.1 - 0.17 11.9 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DDE_3 PF13358.6 GAM43549.1 - 4.5e-33 114.1 0.0 6.6e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 GAM43549.1 - 1.1e-07 31.3 0.0 2.9e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix rve PF00665.26 GAM43549.1 - 0.00034 20.8 0.0 0.00074 19.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_1 PF03184.19 GAM43549.1 - 0.00036 20.2 0.0 0.00053 19.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 GAM43549.1 - 0.023 13.7 0.0 3.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain TPR_12 PF13424.6 GAM43551.1 - 1e-119 391.0 50.8 9.1e-20 70.7 0.2 9.0 3 2 9 12 12 12 11 Tetratricopeptide repeat TPR_10 PF13374.6 GAM43551.1 - 2.5e-91 297.4 9.1 2.1e-12 46.5 0.0 12.2 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_1 PF00515.28 GAM43551.1 - 2.8e-32 109.2 24.6 0.00056 19.6 0.2 11.6 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_7 PF13176.6 GAM43551.1 - 5.7e-31 104.3 17.1 0.022 14.7 0.0 12.2 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 GAM43551.1 - 5.4e-19 66.7 28.2 0.018 15.1 0.2 11.2 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAM43551.1 - 3e-17 61.8 19.2 1.2 10.2 0.0 12.8 12 1 1 13 13 12 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAM43551.1 - 4.7e-17 60.7 20.1 0.21 11.9 0.0 11.0 11 0 0 11 11 11 4 Tetratricopeptide repeat MIT PF04212.18 GAM43551.1 - 1e-15 57.5 0.5 0.77 9.9 0.0 9.1 9 0 0 9 9 8 3 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 GAM43551.1 - 6.6e-15 55.3 9.6 0.00017 21.1 4.4 4.8 1 1 4 5 5 5 4 MalT-like TPR region TPR_16 PF13432.6 GAM43551.1 - 4.1e-12 46.5 23.7 0.064 13.9 0.1 10.0 7 2 2 9 9 9 4 Tetratricopeptide repeat SET PF00856.28 GAM43551.1 - 9.2e-09 35.9 0.8 6.7e-08 33.1 0.8 2.3 1 1 0 1 1 1 1 SET domain ANAPC3 PF12895.7 GAM43551.1 - 5.2e-08 33.0 1.5 0.37 11.1 0.0 5.7 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF676 PF05057.14 GAM43551.1 - 6e-08 32.5 0.1 0.0059 16.1 0.0 2.7 2 0 0 2 2 2 2 Putative serine esterase (DUF676) NACHT PF05729.12 GAM43551.1 - 1.5e-05 25.0 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Abhydrolase_6 PF12697.7 GAM43551.1 - 2.5e-05 25.0 0.9 0.37 11.3 0.1 3.7 3 1 0 3 3 3 2 Alpha/beta hydrolase family TPR_4 PF07721.14 GAM43551.1 - 5.9e-05 23.3 16.3 4.3 8.3 0.2 9.9 11 0 0 11 11 9 1 Tetratricopeptide repeat AAA_16 PF13191.6 GAM43551.1 - 0.00011 22.6 4.6 0.18 12.2 0.4 3.5 2 2 0 2 2 2 2 AAA ATPase domain TPR_3 PF07720.12 GAM43551.1 - 0.00023 21.1 12.1 0.3 11.1 0.0 8.6 10 0 0 10 10 10 1 Tetratricopeptide repeat Hydrolase_4 PF12146.8 GAM43551.1 - 0.00031 20.1 0.0 0.43 9.8 0.0 2.6 2 0 0 2 2 2 2 Serine aminopeptidase, S33 SRP54 PF00448.22 GAM43551.1 - 0.0017 18.0 0.0 1.2 8.8 0.0 3.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Ser_hydrolase PF06821.13 GAM43551.1 - 0.002 18.0 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 1 Serine hydrolase AAA_22 PF13401.6 GAM43551.1 - 0.0023 18.2 0.0 2.5 8.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain PGAP1 PF07819.13 GAM43551.1 - 0.0038 17.0 0.2 1.5 8.4 0.0 2.5 2 0 0 2 2 2 1 PGAP1-like protein DUF2225 PF09986.9 GAM43551.1 - 0.0058 16.4 2.7 0.36 10.5 0.0 3.9 3 2 3 6 6 5 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.6 GAM43551.1 - 0.0064 16.8 8.5 38 5.0 0.0 7.8 8 0 0 8 8 8 0 Tetratricopeptide repeat ResIII PF04851.15 GAM43551.1 - 0.0089 16.1 0.0 3 7.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 GAM43551.1 - 0.0097 15.6 0.0 3.9 7.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAM43551.1 - 0.013 15.1 0.0 12 5.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain TPR_19 PF14559.6 GAM43551.1 - 0.02 15.4 15.8 23 5.6 0.0 7.5 5 2 1 6 6 6 0 Tetratricopeptide repeat CAS_C PF12026.8 GAM43551.1 - 0.021 14.9 0.0 7.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Crk-Associated Substrate C-terminal domain IstB_IS21 PF01695.17 GAM43551.1 - 0.032 14.0 0.1 12 5.6 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein 4HBT_3 PF13622.6 GAM43551.1 - 0.086 13.1 0.4 20 5.3 0.1 2.7 2 0 0 2 2 2 0 Thioesterase-like superfamily TPR_12 PF13424.6 GAM43552.1 - 1.1e-13 51.2 0.1 3e-13 49.9 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM43552.1 - 1.9e-12 46.6 0.2 7.3e-09 35.2 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM43552.1 - 6.2e-07 29.0 1.7 0.0013 18.5 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM43552.1 - 0.00047 20.1 1.2 0.85 9.9 0.4 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM43552.1 - 0.00092 19.7 0.0 0.0039 17.7 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM43552.1 - 0.0018 18.3 0.5 0.2 11.9 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM43552.1 - 0.016 15.2 1.2 2.2 8.5 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM43552.1 - 0.018 15.3 1.1 0.095 12.9 0.1 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 GAM43552.1 - 0.018 15.8 7.5 0.32 11.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM43552.1 - 0.025 14.2 1.0 3.1 7.5 0.1 2.5 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 GAM43552.1 - 0.9 10.2 8.5 5.8 7.6 0.1 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_64 PF16483.5 GAM43553.1 - 6.8e-114 381.0 0.0 7.7e-114 380.8 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Patatin PF01734.22 GAM43555.1 - 6.3e-07 29.8 0.1 0.00015 22.0 0.0 2.5 2 0 0 2 2 2 2 Patatin-like phospholipase Zn-ribbon_8 PF09723.10 GAM43555.1 - 0.95 9.6 5.4 4.2 7.6 0.2 3.5 3 0 0 3 3 3 0 Zinc ribbon domain Prok-RING_4 PF14447.6 GAM43555.1 - 5.9 6.8 23.1 0.047 13.6 5.1 4.2 4 1 0 4 4 4 0 Prokaryotic RING finger family 4 YdjO PF14169.6 GAM43555.1 - 7.3 6.4 10.3 0.39 10.5 0.4 3.3 4 0 0 4 4 4 0 Cold-inducible protein YdjO Zn_clus PF00172.18 GAM43556.1 - 0.014 15.5 1.7 0.028 14.5 1.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2730 PF10805.8 GAM43556.1 - 0.13 12.4 0.1 0.31 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) P2 PF07194.11 GAM43556.1 - 0.14 12.2 0.0 5.6 7.1 0.0 2.3 2 0 0 2 2 2 0 P2 response regulator binding domain Ank_2 PF12796.7 GAM43557.1 - 5.9e-14 52.4 0.0 8.7e-13 48.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM43557.1 - 1.1e-12 48.1 0.2 5.6e-05 23.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM43557.1 - 4.9e-12 44.9 0.2 5e-05 23.4 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAM43557.1 - 1.5e-08 34.7 0.3 0.00076 19.7 0.0 3.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 GAM43557.1 - 2.8e-08 33.9 0.0 0.0044 17.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Phage_holin_3_3 PF16083.5 GAM43557.1 - 0.085 13.0 0.2 0.085 13.0 0.2 1.9 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III VWA PF00092.28 GAM43559.1 - 0.00017 21.9 0.0 0.00033 21.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAM43559.1 - 0.00094 19.8 0.0 0.0024 18.5 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain CFEM PF05730.11 GAM43560.1 - 0.014 15.5 1.8 0.031 14.4 1.8 1.6 1 0 0 1 1 1 0 CFEM domain TIL PF01826.17 GAM43560.1 - 3.4 8.0 5.6 0.38 11.0 0.6 1.9 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain WXG100 PF06013.12 GAM43564.1 - 0.027 14.7 2.1 0.48 10.7 0.3 2.6 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Perilipin PF03036.16 GAM43564.1 - 0.072 12.1 0.6 0.11 11.5 0.6 1.2 1 0 0 1 1 1 0 Perilipin family Sec34 PF04136.15 GAM43564.1 - 0.11 12.4 0.1 9 6.2 0.0 2.5 2 0 0 2 2 2 0 Sec34-like family p450 PF00067.22 GAM43565.1 - 9.8e-51 172.9 0.0 1.4e-50 172.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1911 PF08929.10 GAM43566.1 - 0.12 13.2 0.0 0.32 11.8 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1911) Serine_rich PF08824.10 GAM43567.1 - 0.046 13.7 0.1 0.14 12.1 0.1 1.8 1 1 0 1 1 1 0 Serine rich protein interaction domain TPR_12 PF13424.6 GAM43571.1 - 1.3e-44 150.3 12.9 4.5e-20 71.7 2.4 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAM43571.1 - 1.6e-35 120.0 5.1 1.7e-12 46.8 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAM43571.1 - 1.2e-09 37.5 4.8 0.0034 17.3 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM43571.1 - 3.5e-08 32.9 10.6 0.00055 19.6 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAM43571.1 - 1.7e-06 28.3 2.9 1.5 9.8 0.1 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM43571.1 - 4.4e-06 26.4 3.7 0.29 11.4 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM43571.1 - 6.3e-06 26.0 1.2 0.35 11.2 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAM43571.1 - 0.00054 20.3 0.2 2.8 8.8 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_16 PF13191.6 GAM43571.1 - 0.0006 20.2 0.5 0.0023 18.4 0.5 2.3 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 GAM43571.1 - 0.00068 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ANAPC3 PF12895.7 GAM43571.1 - 0.0085 16.3 0.8 0.34 11.2 0.1 3.0 2 1 2 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 NACHT PF05729.12 GAM43571.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TPR_16 PF13432.6 GAM43571.1 - 0.027 15.1 11.2 0.031 14.9 0.7 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAM43571.1 - 0.038 14.4 0.1 2 9.0 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM43571.1 - 0.064 13.8 1.7 2.2 8.8 0.2 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF1925 PF09094.11 GAM43571.1 - 0.12 12.7 0.4 1e+02 3.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1925) NRBF2_MIT PF17169.4 GAM43571.1 - 0.22 11.8 1.7 30 5.0 0.1 3.4 2 1 1 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 MIT PF04212.18 GAM43571.1 - 0.33 11.0 4.0 26 5.0 0.1 3.9 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain PPR PF01535.20 GAM43571.1 - 3.3 8.1 4.0 65 4.1 0.0 3.7 4 0 0 4 4 3 0 PPR repeat DUF3176 PF11374.8 GAM43572.1 - 1.6e-17 63.6 0.7 6.5e-17 61.7 0.7 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) UPF0767 PF15990.5 GAM43572.1 - 0.033 14.3 0.6 0.097 12.8 0.0 2.0 2 0 0 2 2 2 0 UPF0767 family YccV-like PF08755.11 GAM43573.1 - 8.6e-29 99.9 0.1 2e-28 98.7 0.1 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like FA_hydroxylase PF04116.13 GAM43573.1 - 4.4e-25 88.6 17.4 4.4e-25 88.6 17.4 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Transglut_core2 PF13369.6 GAM43573.1 - 1.7e-14 53.7 0.0 3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 GAM43573.1 - 1.5e-09 37.6 0.9 3.6e-09 36.4 0.9 1.8 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 GAM43573.1 - 1.3e-06 28.9 0.3 3.8e-06 27.4 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 GAM43573.1 - 1.7e-06 27.7 0.1 4.1e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 GAM43573.1 - 0.12 12.4 1.2 0.47 10.5 1.2 2.0 1 1 0 1 1 1 0 F-box-like domain DnaJ PF00226.31 GAM43574.1 - 5.2e-25 87.3 0.5 1.3e-24 86.1 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.7 GAM43574.1 - 5.3e-12 45.7 11.5 7.6e-08 32.5 3.7 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAM43574.1 - 1.2e-10 41.4 14.4 1.1e-08 35.2 7.5 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAM43574.1 - 1.6e-08 34.8 10.6 0.00091 19.5 2.5 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAM43574.1 - 1.3e-05 25.6 7.1 0.058 14.3 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM43574.1 - 3.7e-05 23.9 9.7 0.047 14.2 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type RPT PF13446.6 GAM43574.1 - 0.011 15.6 0.0 0.04 13.8 0.0 1.9 1 0 0 1 1 1 0 A repeated domain in UCH-protein zf-C2H2_6 PF13912.6 GAM43574.1 - 0.041 13.9 11.8 0.046 13.7 3.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2256 PF10013.9 GAM43574.1 - 0.073 13.2 0.4 10 6.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Phage_int_SAM_1 PF02899.17 GAM43574.1 - 0.21 11.9 1.6 0.71 10.2 1.6 1.9 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain LIM PF00412.22 GAM43574.1 - 0.46 10.7 4.7 1.4 9.2 0.8 2.4 2 0 0 2 2 2 0 LIM domain R3H PF01424.22 GAM43575.1 - 3.1e-14 52.7 0.1 6.9e-14 51.6 0.1 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 GAM43575.1 - 6.6e-11 41.9 0.3 2.2e-10 40.2 0.3 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAM43575.1 - 0.0014 18.7 0.3 0.0014 18.7 0.3 2.9 3 0 0 3 3 3 1 G-patch domain Peptidase_C54 PF03416.19 GAM43576.1 - 2.2e-97 325.8 0.0 2.9e-97 325.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Apt1 PF10351.9 GAM43576.1 - 0.097 11.5 3.4 0.12 11.2 3.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 GAM43576.1 - 0.21 9.8 5.0 0.28 9.4 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.13 GAM43576.1 - 0.83 7.9 3.5 1.2 7.5 3.5 1.1 1 0 0 1 1 1 0 Menin Histone PF00125.24 GAM43577.1 - 9.5e-17 61.6 1.8 1.9e-16 60.6 1.8 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 GAM43577.1 - 0.00029 21.2 0.0 0.00047 20.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 GAM43577.1 - 0.0025 18.1 1.3 0.003 17.8 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 GAM43578.1 - 4.3e-21 74.4 2.8 7.6e-21 73.6 2.8 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 GAM43578.1 - 2.8e-17 63.3 0.0 3.8e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAM43578.1 - 1e-05 25.7 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.15 GAM43579.1 - 3.5e-09 36.6 1.0 6.4e-09 35.7 1.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) 2-oxoacid_dh PF00198.23 GAM43580.1 - 8.3e-81 270.8 0.0 1.1e-80 270.4 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAM43580.1 - 7.9e-17 60.9 1.3 1.6e-16 59.8 1.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAM43580.1 - 5.6e-05 22.9 0.2 0.0014 18.4 0.1 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 GAM43580.1 - 0.00012 22.8 0.3 0.024 15.3 0.1 2.4 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 GAM43580.1 - 0.006 16.5 0.2 0.3 11.1 0.0 2.5 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 GAM43580.1 - 0.048 13.5 1.2 0.16 11.8 0.2 2.2 2 0 0 2 2 2 0 Glycine cleavage H-protein DUF2052 PF09747.9 GAM43580.1 - 1.7 8.7 4.9 2.6 8.2 4.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 GAM43580.1 - 4 7.2 9.3 5.1 6.8 9.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FmrO PF07091.11 GAM43581.1 - 0.083 12.4 0.1 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) Peptidase_C12 PF01088.21 GAM43582.1 - 2.1e-58 197.5 0.0 3e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Nrap_D4 PF17405.2 GAM43584.1 - 6.2e-58 195.7 0.1 1e-57 194.9 0.1 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 GAM43584.1 - 6.4e-45 152.6 0.2 1.6e-43 148.1 0.0 2.6 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap PF03813.14 GAM43584.1 - 1.6e-42 145.1 0.3 2.8e-42 144.3 0.3 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 GAM43584.1 - 6.9e-42 143.2 0.0 1.4e-41 142.3 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D5 PF17406.2 GAM43584.1 - 4.6e-38 130.5 0.2 1.2e-37 129.2 0.2 1.7 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 DUF948 PF06103.11 GAM43584.1 - 0.0016 18.6 0.1 0.013 15.8 0.0 2.2 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Rx_N PF18052.1 GAM43584.1 - 0.12 12.6 0.8 22 5.4 0.2 2.5 2 0 0 2 2 2 0 Rx N-terminal domain Cys_Met_Meta_PP PF01053.20 GAM43585.1 - 1.7e-33 115.7 0.0 2.3e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAM43585.1 - 0.00032 20.0 0.0 0.00045 19.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MRP-L20 PF12824.7 GAM43586.1 - 6.5e-57 192.3 6.9 7.5e-57 192.1 6.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Peptidase_M20 PF01546.28 GAM43587.1 - 7.8e-33 113.9 0.0 9.9e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM43587.1 - 3.7e-13 49.4 0.0 6.8e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAM43587.1 - 0.035 13.8 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 DUF5395 PF17373.2 GAM43587.1 - 0.14 12.8 0.1 0.34 11.6 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5395) SMC_N PF02463.19 GAM43588.1 - 2.2e-18 66.5 21.2 2e-11 43.7 0.4 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAM43588.1 - 6.1e-13 49.7 22.2 6.1e-13 49.7 22.2 5.8 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 GAM43588.1 - 1.5e-10 41.3 36.0 1.8e-10 41.1 18.4 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 GAM43588.1 - 3.5e-08 33.6 10.3 1.5e-06 28.3 2.3 3.5 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_hinge PF06470.13 GAM43588.1 - 2.8e-05 24.4 0.9 0.00011 22.5 0.1 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 GAM43588.1 - 0.00072 19.2 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 GAM43588.1 - 0.074 13.6 0.1 0.074 13.6 0.1 6.0 3 2 2 5 5 5 0 ABC transporter Nrap_D6 PF17407.2 GAM43588.1 - 0.078 13.2 0.0 0.34 11.1 0.0 2.1 1 0 0 1 1 1 0 Nrap protein domain 6 Spc7 PF08317.11 GAM43588.1 - 3.5 6.4 91.1 0.25 10.2 12.8 5.6 4 2 2 6 6 6 0 Spc7 kinetochore protein DEAD PF00270.29 GAM43589.1 - 6.3e-43 146.6 0.1 8.9e-43 146.1 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM43589.1 - 3.5e-28 98.2 1.0 6.2e-27 94.1 0.4 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM43589.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAM43589.1 - 0.15 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Mito_carr PF00153.27 GAM43590.1 - 4.5e-53 177.2 3.7 5.8e-23 80.6 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein PCRF PF03462.18 GAM43591.1 - 2.5e-49 167.8 0.1 7.4e-49 166.3 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 GAM43591.1 - 4e-33 113.8 0.4 8.9e-33 112.7 0.4 1.6 1 0 0 1 1 1 1 RF-1 domain DnaJ PF00226.31 GAM43592.1 - 5.2e-22 77.7 0.8 1.9e-21 75.9 0.8 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 GAM43592.1 - 1e-16 61.2 2.0 0.00017 22.0 0.7 4.2 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAM43592.1 - 2.3e-16 58.8 0.0 7.3e-06 25.6 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM43592.1 - 1.2e-15 56.3 6.6 0.0018 18.2 0.0 7.6 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAM43592.1 - 4.5e-14 51.9 6.9 0.075 13.9 0.0 7.0 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAM43592.1 - 2.2e-13 50.1 5.5 4.2e-05 23.6 0.1 4.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM43592.1 - 9.1e-12 44.2 0.0 0.0076 16.4 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAM43592.1 - 1.9e-09 37.6 5.9 3.1 8.6 0.0 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM43592.1 - 1.2e-07 32.2 4.9 0.0013 19.3 0.1 5.2 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAM43592.1 - 5.2e-07 29.3 0.0 0.015 15.0 0.0 5.2 4 1 1 5 5 5 1 TPR repeat TPR_7 PF13176.6 GAM43592.1 - 1.3e-06 28.0 0.9 1.9 8.7 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM43592.1 - 7.5e-06 26.1 6.3 0.071 13.4 0.0 4.8 4 2 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM43592.1 - 1.8e-05 24.9 12.5 0.018 15.2 1.2 5.2 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GAM43592.1 - 3.1e-05 24.1 0.0 0.033 14.6 0.0 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 GAM43592.1 - 0.0021 17.7 0.3 0.017 14.8 0.0 2.5 3 1 1 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) PknG_TPR PF16918.5 GAM43592.1 - 0.0052 15.6 0.1 0.44 9.2 0.0 2.9 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_20 PF14561.6 GAM43592.1 - 0.01 16.2 2.3 1.6 9.1 0.1 3.6 3 2 1 4 4 3 0 Tetratricopeptide repeat KORA PF16509.5 GAM43592.1 - 0.011 16.0 0.8 0.03 14.6 0.2 2.1 2 1 0 2 2 2 0 TrfB plasmid transcriptional repressor Med15 PF09606.10 GAM43592.1 - 0.012 14.4 0.1 0.018 13.8 0.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Alkyl_sulf_dimr PF14863.6 GAM43592.1 - 0.087 13.3 2.0 16 6.0 0.1 3.9 3 2 0 3 3 3 0 Alkyl sulfatase dimerisation Syntaxin_2 PF14523.6 GAM43592.1 - 0.2 12.0 2.8 1.1 9.6 0.5 2.5 2 0 0 2 2 2 0 Syntaxin-like protein Fis1_TPR_C PF14853.6 GAM43592.1 - 0.7 10.0 2.9 83 3.4 0.0 4.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat SLATT_5 PF18160.1 GAM43592.1 - 2.5 7.4 5.7 5.9 6.2 1.2 2.3 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 PCMT PF01135.19 GAM43593.1 - 1.9e-54 184.6 0.0 3.6e-54 183.7 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.25 GAM43593.1 - 1.4e-40 139.4 0.0 4.4e-38 131.2 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM43593.1 - 6.7e-09 35.4 0.0 4.2e-05 23.0 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Methyltransf_31 PF13847.6 GAM43593.1 - 6.5e-06 26.0 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM43593.1 - 7.5e-05 23.4 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAM43593.1 - 0.0016 18.5 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain APH PF01636.23 GAM43593.1 - 0.0025 17.8 0.1 0.69 9.8 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family MetW PF07021.12 GAM43593.1 - 0.047 13.3 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Pkinase_fungal PF17667.1 GAM43593.1 - 0.054 12.3 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Methyltransf_11 PF08241.12 GAM43593.1 - 0.06 14.0 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAM43593.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAM43593.1 - 0.11 13.3 0.0 0.29 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 GAM43593.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Cnd1_N PF12922.7 GAM43594.1 - 7.4e-63 211.3 0.5 2.1e-62 209.8 0.5 1.9 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 GAM43594.1 - 9.4e-49 165.6 3.2 2.5e-43 147.9 0.5 3.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM43594.1 - 1e-10 41.9 3.3 0.00017 21.9 0.0 5.2 4 1 0 5 5 5 2 HEAT repeats HEAT PF02985.22 GAM43594.1 - 3.4e-09 36.2 7.9 0.058 13.7 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat Adaptin_N PF01602.20 GAM43594.1 - 8e-07 28.0 6.1 0.009 14.6 0.6 4.4 3 1 0 3 3 3 2 Adaptin N terminal region RTP1_C1 PF10363.9 GAM43594.1 - 3.9e-05 23.8 0.2 0.21 11.8 0.0 4.1 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 GAM43594.1 - 0.0022 17.3 0.5 0.0022 17.3 0.5 3.3 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 GAM43594.1 - 0.0025 18.3 8.7 0.32 11.6 0.0 5.3 5 1 0 5 5 5 1 HEAT-like repeat YtzH PF14165.6 GAM43594.1 - 0.11 12.9 0.3 2.7 8.4 0.0 2.7 2 0 0 2 2 2 0 YtzH-like protein Oxysterol_BP PF01237.18 GAM43595.1 - 3.4e-55 187.4 0.7 8.2e-54 182.8 0.7 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein OTU PF02338.19 GAM43596.1 - 5.5e-06 26.9 0.0 9.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DUF4678 PF15727.5 GAM43596.1 - 0.067 12.4 1.7 0.094 12.0 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) Bromodomain PF00439.25 GAM43597.1 - 4.2e-31 106.8 6.4 1.3e-18 66.8 0.6 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 GAM43597.1 - 1.6e-18 66.7 0.9 3.3e-18 65.7 0.9 1.6 1 0 0 1 1 1 1 BAH domain IER PF05760.12 GAM43597.1 - 0.00012 22.5 1.5 0.00012 22.5 1.5 3.3 3 0 0 3 3 3 2 Immediate early response protein (IER) BBS2_N PF14781.6 GAM43597.1 - 0.19 11.7 0.2 0.38 10.7 0.2 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal CDC45 PF02724.14 GAM43597.1 - 0.81 7.9 17.3 0.0048 15.3 6.0 2.0 2 0 0 2 2 2 0 CDC45-like protein zf-CCCH_4 PF18044.1 GAM43598.1 - 0.01 15.6 0.2 0.023 14.5 0.2 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAM43598.1 - 0.1 12.7 0.7 0.2 11.8 0.7 1.4 1 0 0 1 1 1 0 Zinc finger domain Torus PF16131.5 GAM43598.1 - 0.15 12.8 0.0 0.47 11.2 0.0 1.8 1 0 0 1 1 1 0 Torus domain TBX PF12598.8 GAM43598.1 - 9.1 7.2 8.6 8.4 7.3 3.7 2.8 2 0 0 2 2 2 0 T-box transcription factor CdvA PF18822.1 GAM43599.1 - 0.002 17.9 1.5 0.0033 17.3 1.5 1.3 1 0 0 1 1 1 1 CdvA-like coiled-coil domain TPR_MLP1_2 PF07926.12 GAM43599.1 - 0.0021 18.1 2.9 0.0036 17.4 2.9 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein RLL PF10036.9 GAM43599.1 - 0.017 15.0 1.6 0.021 14.7 1.6 1.1 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein Med9 PF07544.13 GAM43599.1 - 0.023 14.8 2.2 0.044 13.9 2.2 1.5 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 MetOD2 PF18548.1 GAM43599.1 - 0.053 13.6 0.5 0.12 12.5 0.5 1.6 1 0 0 1 1 1 0 Metanogen output domain 2 TSC22 PF01166.18 GAM43599.1 - 0.11 12.8 2.7 0.44 10.9 0.2 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4349 PF14257.6 GAM43599.1 - 0.11 11.9 4.1 0.18 11.2 4.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) SlyX PF04102.12 GAM43599.1 - 1.1 9.9 3.7 9.7 6.9 0.1 2.5 2 1 0 2 2 2 0 SlyX DUF4140 PF13600.6 GAM43599.1 - 2.9 8.4 6.9 16 6.0 1.6 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 GAM43599.1 - 3 8.1 8.0 6 7.2 1.1 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Sel1 PF08238.12 GAM43600.1 - 9.5e-21 73.8 20.7 1.8e-07 31.6 0.0 7.1 6 0 0 6 6 6 6 Sel1 repeat TPR_1 PF00515.28 GAM43600.1 - 0.0061 16.3 0.6 0.052 13.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM43600.1 - 1.5 9.1 0.0 1.5 9.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM43600.1 - 2.7 9.1 4.3 8.3 7.5 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Helicase_C_2 PF13307.6 GAM43601.1 - 8e-56 188.9 0.0 2.6e-55 187.2 0.0 2.0 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 GAM43601.1 - 2.6e-51 173.7 1.8 6.2e-51 172.5 1.8 1.7 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 GAM43601.1 - 0.00018 21.2 0.2 0.004 16.8 0.0 2.6 2 0 0 2 2 2 1 Helical and beta-bridge domain ResIII PF04851.15 GAM43601.1 - 0.00098 19.2 0.4 1.7 8.7 0.1 3.0 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM43601.1 - 0.0095 15.7 0.4 0.55 10.0 0.3 2.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AbiH PF14253.6 GAM43601.1 - 0.034 14.0 1.7 0.082 12.8 1.2 1.8 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH PhoH PF02562.16 GAM43601.1 - 0.083 12.3 0.0 3.7 6.9 0.0 2.6 2 1 1 3 3 3 0 PhoH-like protein AAA_22 PF13401.6 GAM43601.1 - 0.38 11.0 4.8 0.58 10.4 0.1 3.0 3 1 0 3 3 3 0 AAA domain DUF4349 PF14257.6 GAM43601.1 - 0.72 9.3 5.5 3.1 7.2 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) PilJ PF13675.6 GAM43601.1 - 3.7 7.6 7.3 1 9.4 1.2 2.8 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Abhydrolase_6 PF12697.7 GAM43602.1 - 0.00038 21.1 0.1 0.00051 20.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM43602.1 - 0.002 17.4 0.0 0.0066 15.7 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAM43602.1 - 0.032 13.7 0.0 6.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family PLDc PF00614.22 GAM43603.1 - 2.8e-15 55.8 0.2 1.8e-07 31.1 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GAM43603.1 - 1.3e-12 47.8 0.0 2e-06 27.7 0.0 3.2 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 GAM43603.1 - 4e-09 36.5 0.1 1.9e-08 34.3 0.1 2.3 1 0 0 1 1 1 1 PX domain Glyco_transf_28 PF03033.20 GAM43604.1 - 2.6e-11 43.7 0.0 5.2e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyoxalase_6 PF18029.1 GAM43605.1 - 0.042 14.6 0.1 0.73 10.7 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain PAS_9 PF13426.7 GAM43606.1 - 6.4e-28 97.1 0.0 1.3e-16 60.7 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 GAM43606.1 - 5.8e-23 81.0 0.0 3.1e-13 49.8 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 GAM43606.1 - 8.8e-17 61.1 0.0 2.8e-07 30.5 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.27 GAM43606.1 - 8.3e-15 54.1 8.9 1.7e-14 53.1 8.9 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.6 GAM43606.1 - 1.4e-10 41.3 0.0 4.9e-06 26.6 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 GAM43606.1 - 6.5e-10 39.2 0.0 0.00098 19.4 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 GAM43606.1 - 0.015 15.4 0.0 0.057 13.5 0.0 1.9 2 0 0 2 2 2 0 PAS domain PAS_2 PF08446.11 GAM43606.1 - 0.048 14.3 0.0 4.8 7.9 0.0 3.2 3 0 0 3 3 3 0 PAS fold Nudix_N_2 PF14803.6 GAM43606.1 - 0.63 10.0 3.6 1.2 9.2 3.6 1.4 1 0 0 1 1 1 0 Nudix N-terminal Ras PF00071.22 GAM43607.1 - 3.5e-30 104.7 0.1 1.8e-28 99.2 0.1 2.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 GAM43607.1 - 0.0016 18.6 0.0 0.0061 16.8 0.0 2.0 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM43607.1 - 0.015 14.8 0.0 1.2 8.5 0.0 2.2 1 1 0 1 1 1 0 ADP-ribosylation factor family TIP_N PF12457.8 GAM43607.1 - 0.31 11.4 6.9 0.16 12.4 3.7 2.1 2 0 0 2 2 2 0 Tuftelin interacting protein N terminal Cnn_1N PF07989.11 GAM43608.1 - 6.8e-23 80.6 11.3 6.8e-23 80.6 11.3 13.1 9 1 2 12 12 12 3 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 GAM43608.1 - 7.9e-18 64.5 26.4 2.2e-15 56.7 18.9 12.5 15 1 1 16 16 16 3 Micro-tubular organiser Mto1 C-term Mto2-binding region Fib_alpha PF08702.10 GAM43608.1 - 0.0067 16.6 10.4 0.0067 16.6 10.4 8.0 4 2 3 8 8 8 1 Fibrinogen alpha/beta chain family DUF2935 PF11155.8 GAM43608.1 - 0.1 12.9 4.9 4.1 7.8 0.2 4.9 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) QRPTase_C PF01729.19 GAM43609.1 - 1.3e-47 161.7 0.4 1.3e-45 155.2 0.4 2.1 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 GAM43609.1 - 1e-22 80.0 0.1 3.9e-22 78.1 0.0 2.1 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Isochorismatase PF00857.20 GAM43610.1 - 6e-17 62.4 0.1 2.5e-16 60.3 0.1 1.8 1 1 0 1 1 1 1 Isochorismatase family LETM1 PF07766.13 GAM43611.1 - 5.7e-09 35.7 0.0 4.2e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 LETM1-like protein zf-C2H2_11 PF16622.5 GAM43611.1 - 0.34 10.7 4.6 0.36 10.6 1.2 2.5 1 1 1 2 2 2 0 zinc-finger C2H2-type PAP_assoc PF03828.19 GAM43612.1 - 0.0055 16.9 0.5 0.039 14.2 0.0 2.5 2 1 0 2 2 2 1 Cid1 family poly A polymerase Transp_cyt_pur PF02133.15 GAM43615.1 - 1.8e-88 297.2 34.2 3.8e-87 292.9 34.2 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.6 GAM43616.1 - 9.7e-29 100.5 0.1 1.5e-28 99.9 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM43616.1 - 8.1e-19 68.0 0.0 2.8e-18 66.3 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CorA PF01544.18 GAM43617.1 - 4e-05 23.1 0.2 7.4e-05 22.2 0.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_S8 PF00082.22 GAM43619.1 - 8.3e-18 64.7 0.1 1.7e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 Subtilase family AAA_16 PF13191.6 GAM43620.1 - 6.3e-07 29.9 0.1 6.3e-07 29.9 0.1 3.4 4 1 1 5 5 5 1 AAA ATPase domain AAA PF00004.29 GAM43620.1 - 0.0011 19.4 0.0 0.007 16.8 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM43620.1 - 0.0012 19.1 0.0 0.004 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 GAM43620.1 - 0.0015 18.5 0.1 0.0092 15.9 0.0 2.4 2 1 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 GAM43620.1 - 0.0063 15.7 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 GAM43620.1 - 0.078 13.5 0.0 0.43 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain zf-C2H2_2 PF12756.7 GAM43620.1 - 0.15 12.4 2.0 5.8 7.3 0.0 3.9 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAM43620.1 - 0.16 12.9 2.5 38 5.5 0.2 4.2 3 0 0 3 3 3 0 C2H2-type zinc finger ABC_tran PF00005.27 GAM43620.1 - 0.16 12.5 0.0 0.64 10.5 0.0 2.0 1 0 0 1 1 1 0 ABC transporter Macro_2 PF14519.6 GAM43621.1 - 3.3e-07 29.9 0.0 5.8e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Macro-like domain Macro PF01661.21 GAM43621.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.6 1 1 0 1 1 1 0 Macro domain Glyco_transf_20 PF00982.21 GAM43623.1 - 3.9e-149 497.4 0.0 5.6e-149 496.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAM43623.1 - 6.8e-77 257.7 0.0 1.9e-76 256.3 0.0 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase F_bP_aldolase PF01116.20 GAM43623.1 - 1.4e-54 185.5 0.4 1.2e-53 182.4 0.4 2.2 1 1 0 1 1 1 1 Fructose-bisphosphate aldolase class-II BRD4_CDT PF17105.5 GAM43623.1 - 0.21 11.2 0.1 0.45 10.2 0.1 1.5 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Ad_cyc_g-alpha PF08509.11 GAM43623.1 - 0.45 10.3 1.6 2.6 7.8 0.0 2.8 3 0 0 3 3 3 0 Adenylate cyclase G-alpha binding domain Sugar_tr PF00083.24 GAM43624.1 - 6.3e-100 335.2 18.5 7.6e-100 334.9 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM43624.1 - 2e-20 73.0 26.5 2.2e-15 56.4 5.2 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily PNP_UDP_1 PF01048.20 GAM43625.1 - 2.2e-11 43.4 1.3 7.4e-11 41.7 1.3 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.22 GAM43625.1 - 2.7e-09 36.6 0.0 4.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 GAM43625.1 - 7.6e-08 32.9 0.4 2.5e-06 28.0 0.1 3.3 3 1 0 3 3 3 1 AAA ATPase domain TPR_10 PF13374.6 GAM43625.1 - 5.1e-06 26.2 0.0 0.0033 17.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat adh_short_C2 PF13561.6 GAM43625.1 - 1.6e-05 24.6 0.0 5.3e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ATPase_2 PF01637.18 GAM43625.1 - 5.7e-05 23.1 0.0 0.00034 20.6 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 GAM43625.1 - 7.6e-05 22.7 0.0 0.00019 21.4 0.0 1.7 1 1 0 1 1 1 1 NACHT domain adh_short PF00106.25 GAM43625.1 - 8.4e-05 22.1 0.0 0.00021 20.8 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase TPR_12 PF13424.6 GAM43625.1 - 0.00012 22.2 0.9 0.00074 19.8 0.9 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat AAA_22 PF13401.6 GAM43625.1 - 0.0042 17.3 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAM43625.1 - 0.023 14.8 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAM43625.1 - 0.049 13.7 0.0 0.18 11.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAM43625.1 - 0.072 13.1 0.0 0.56 10.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 GAM43625.1 - 0.18 12.3 0.0 0.49 10.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 GAM43625.1 - 0.18 11.2 0.0 0.43 10.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Aspzincin_M35 PF14521.6 GAM43627.1 - 1.4e-08 35.4 3.0 1.4e-07 32.1 0.4 3.1 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 GAM43627.1 - 0.00035 19.6 0.1 0.00082 18.3 0.1 1.5 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family adh_short_C2 PF13561.6 GAM43628.1 - 1.7e-14 53.9 0.1 2.3e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM43628.1 - 2.6e-13 49.9 0.1 1.2e-12 47.7 0.1 1.8 1 1 1 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 GAM43628.1 - 3.3e-06 26.7 0.0 8.7e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AAA_22 PF13401.6 GAM43628.1 - 0.039 14.2 0.0 2.8 8.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain RmlD_sub_bind PF04321.17 GAM43628.1 - 0.041 13.0 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 GAM43628.1 - 0.087 12.4 0.2 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 GAM43628.1 - 0.12 12.3 0.7 0.32 10.8 0.1 1.8 1 1 1 2 2 2 0 NAD(P)H-binding N_BRCA1_IG PF16158.5 GAM43630.1 - 2.1e-32 111.9 0.3 7.2e-32 110.1 0.3 2.0 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 GAM43630.1 - 2.3e-22 78.5 52.3 1.7e-08 34.1 8.0 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 GAM43630.1 - 0.42 11.0 48.0 0.17 12.2 8.8 4.6 4 0 0 4 4 4 0 C1 domain Btz PF09405.10 GAM43631.1 - 1.9e-31 109.0 4.8 4.4e-31 107.8 4.8 1.6 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding RRM_1 PF00076.22 GAM43632.1 - 3.2e-24 84.5 0.6 6.8e-14 51.5 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM43632.1 - 0.00071 19.5 0.6 0.54 10.3 0.0 2.7 2 1 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GAM43632.1 - 0.012 15.7 0.0 0.39 10.9 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif Spt20 PF12090.8 GAM43632.1 - 0.21 11.1 2.2 0.29 10.7 0.1 2.0 2 0 0 2 2 2 0 Spt20 family HSP90 PF00183.18 GAM43632.1 - 0.78 8.6 8.0 1.3 7.8 8.0 1.4 1 0 0 1 1 1 0 Hsp90 protein DNA_pol_phi PF04931.13 GAM43632.1 - 0.84 7.7 11.6 1.2 7.2 11.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 GAM43632.1 - 2.1 6.8 4.3 3.4 6.1 4.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ino80_Iec3 PF14612.6 GAM43633.1 - 1.1e-80 271.7 3.1 1.1e-80 271.7 3.1 1.5 2 0 0 2 2 2 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling RdRP_2 PF00978.21 GAM43633.1 - 0.07 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase Sec7 PF01369.20 GAM43634.1 - 3.8e-27 95.2 0.0 8e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 GAM43634.1 - 2.8e-19 69.6 0.0 1.2e-18 67.6 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain RRM_1 PF00076.22 GAM43635.1 - 1.5e-09 37.5 0.2 3.3e-09 36.4 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 GAM43636.1 - 2.8e-27 95.6 62.4 2.5e-19 69.4 37.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM43636.1 - 0.00049 19.1 10.9 0.00049 19.1 10.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter YesK PF14150.6 GAM43636.1 - 0.21 11.8 10.7 1.9 8.7 1.2 3.6 3 0 0 3 3 3 0 YesK-like protein MFS_1_like PF12832.7 GAM43636.1 - 0.32 9.8 19.1 0.15 10.9 10.6 2.8 1 1 2 3 3 3 0 MFS_1 like family Fungal_trans PF04082.18 GAM43637.1 - 1.3e-10 40.8 2.4 2e-10 40.1 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4413 PF14372.6 GAM43637.1 - 0.091 13.1 1.4 3.1 8.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4413) DUF2408 PF10303.9 GAM43637.1 - 0.13 12.8 0.7 3 8.4 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) Asp_protease_2 PF13650.6 GAM43638.1 - 8e-17 61.7 0.0 5.5e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GAM43638.1 - 3.8e-16 59.4 0.0 5.4e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GAM43638.1 - 7.3e-09 35.5 0.0 0.00099 18.9 0.0 2.5 2 1 0 2 2 2 2 Retroviral aspartyl protease Asp_protease PF09668.10 GAM43638.1 - 2.2e-06 27.5 0.0 0.012 15.4 0.0 2.6 2 1 0 2 2 2 2 Aspartyl protease RVP PF00077.20 GAM43638.1 - 0.0002 21.6 0.0 0.013 15.8 0.0 3.0 2 1 0 2 2 2 1 Retroviral aspartyl protease Helo_like_N PF17111.5 GAM43638.1 - 0.041 13.3 0.1 0.074 12.4 0.0 1.4 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins CRAL_TRIO PF00650.20 GAM43639.1 - 7.9e-41 139.4 0.3 1.2e-40 138.8 0.3 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAM43639.1 - 8.4e-11 41.9 0.1 2.4e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAM43639.1 - 8.6e-09 35.7 0.0 1.4e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain FXR_C1 PF16096.5 GAM43640.1 - 0.15 12.3 0.3 0.15 12.3 0.3 2.9 3 0 0 3 3 3 0 Fragile X-related 1 protein C-terminal region 2 ECR1_N PF14382.6 GAM43641.1 - 3.6e-13 49.0 1.0 1.2e-12 47.4 1.1 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 GAM43641.1 - 1.2e-05 25.5 0.7 2.5e-05 24.5 0.7 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 GAM43641.1 - 0.004 17.8 0.4 0.53 10.9 0.1 2.8 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 DUF3759 PF12585.8 GAM43642.1 - 2.5e-35 120.4 4.2 3.4e-35 119.9 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) MyTH4 PF00784.17 GAM43642.1 - 0.066 13.7 0.0 0.11 13.1 0.0 1.4 1 1 0 1 1 1 0 MyTH4 domain DUF2939 PF11159.8 GAM43642.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Amidase PF01425.21 GAM43643.1 - 1.8e-66 225.0 0.0 2.3e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 Amidase Fungal_trans PF04082.18 GAM43644.1 - 4.6e-12 45.5 1.8 4.9e-12 45.5 0.4 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 GAM43645.1 - 1.2e-37 130.0 0.1 2.2e-34 119.3 0.1 3.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM43645.1 - 0.00029 21.0 0.1 0.0006 20.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM43645.1 - 0.00062 19.1 0.1 0.00097 18.5 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM43645.1 - 0.0012 18.1 0.1 0.0018 17.5 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAM43645.1 - 0.0013 18.0 0.1 0.0023 17.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM43645.1 - 0.012 15.2 0.5 0.021 14.4 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM43645.1 - 0.023 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 GAM43645.1 - 0.029 14.9 0.1 0.07 13.7 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM43645.1 - 0.057 12.1 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 GAM43645.1 - 0.07 12.2 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Glyoxalase PF00903.25 GAM43646.1 - 5.3e-08 33.1 1.5 1.3e-07 31.8 1.2 1.8 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Abhydrolase_1 PF00561.20 GAM43648.1 - 2.4e-25 89.7 0.1 8.1e-25 87.9 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM43648.1 - 5.8e-14 53.2 0.0 8e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM43648.1 - 1.3e-07 31.1 0.0 0.00011 21.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 GAM43648.1 - 0.053 12.4 0.0 0.077 11.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 GAM43648.1 - 0.12 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Mycobact_memb PF05423.13 GAM43649.1 - 0.043 13.7 0.1 0.075 13.0 0.1 1.4 1 0 0 1 1 1 0 Mycobacterium membrane protein DUF5559 PF17714.1 GAM43649.1 - 0.059 13.3 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5559) DUF2749 PF10907.8 GAM43649.1 - 0.079 13.1 0.2 0.18 12.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Vpu PF00558.19 GAM43649.1 - 0.12 12.1 0.9 0.33 10.7 0.1 1.9 2 0 0 2 2 2 0 Vpu protein DUF4834 PF16118.5 GAM43649.1 - 0.47 11.4 5.1 5.4 8.1 5.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Zn_clus PF00172.18 GAM43650.1 - 6.7e-05 22.9 11.7 0.00014 21.9 11.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_1 PF00232.18 GAM43651.1 - 1.7e-110 369.6 0.0 1.6e-68 231.2 0.4 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 Bac_rhamnosid6H PF17389.2 GAM43652.1 - 1.1e-117 393.1 0.0 1.4e-117 392.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 GAM43652.1 - 1.3e-54 184.6 0.0 2.7e-54 183.6 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 GAM43652.1 - 3.9e-26 91.0 0.0 7.2e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 GAM43652.1 - 4e-12 45.7 0.0 1.1e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain PD40 PF07676.12 GAM43653.1 - 0.058 13.4 0.1 0.29 11.1 0.1 2.3 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Sugar_tr PF00083.24 GAM43654.1 - 1.8e-66 224.9 23.7 2.1e-66 224.7 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM43654.1 - 3.4e-18 65.7 29.1 1.8e-11 43.5 16.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Na_Ca_ex PF01699.24 GAM43655.1 - 9.2e-31 106.8 21.3 2.8e-16 59.8 6.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein UPF0220 PF05255.11 GAM43655.1 - 0.0092 15.5 0.1 0.036 13.6 0.0 2.0 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0220) DHHC PF01529.20 GAM43655.1 - 2.1 8.4 0.0 2.1 8.4 0.0 3.4 4 0 0 4 4 4 0 DHHC palmitoyltransferase Ion_trans PF00520.31 GAM43655.1 - 2.2 7.5 12.0 2.6 7.2 3.4 2.8 2 1 0 2 2 2 0 Ion transport protein Sdh_cyt PF01127.22 GAM43655.1 - 5.1 7.2 9.6 0.45 10.6 0.2 3.3 2 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sugar_tr PF00083.24 GAM43656.1 - 2.2e-122 409.2 19.3 3.8e-122 408.4 19.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM43656.1 - 1.6e-30 106.2 62.0 5.6e-25 88.0 36.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box PF00646.33 GAM43657.1 - 0.0015 18.4 0.2 0.0049 16.7 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAM43657.1 - 0.029 14.3 0.1 0.089 12.7 0.1 1.9 1 0 0 1 1 1 0 F-box-like CoA_transf_3 PF02515.17 GAM43658.1 - 2e-46 158.8 0.0 2.7e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Ank_2 PF12796.7 GAM43659.1 - 4e-47 158.7 8.7 3.4e-13 50.0 0.0 5.7 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 GAM43659.1 - 4.5e-37 124.9 19.4 7.5e-05 23.0 0.0 10.4 10 1 0 10 10 8 7 Ankyrin repeat Ank_4 PF13637.6 GAM43659.1 - 4.8e-35 119.5 5.5 1.8e-08 34.8 0.1 6.7 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM43659.1 - 2.5e-33 110.3 4.9 8.8e-06 25.7 0.0 10.0 9 1 1 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 GAM43659.1 - 2.3e-29 101.0 3.7 0.00014 22.1 0.0 8.4 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Methyltransf_23 PF13489.6 GAM43659.1 - 1.6e-22 80.1 0.1 4.6e-22 78.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM43659.1 - 2.5e-10 40.3 0.0 8.5e-09 35.4 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM43659.1 - 4.9e-09 36.8 0.0 3.8e-08 33.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM43659.1 - 1.7e-06 28.7 0.0 8.2e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM43659.1 - 3.7e-05 24.3 0.0 0.00015 22.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 GAM43659.1 - 0.001 19.2 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 GAM43659.1 - 0.01 15.4 0.0 0.1 12.2 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.17 GAM43659.1 - 0.042 13.3 0.0 0.16 11.4 0.0 2.0 1 0 0 1 1 1 0 Putative methyltransferase CARD PF00619.21 GAM43659.1 - 0.053 13.5 0.2 5.3 7.2 0.0 3.0 3 0 0 3 3 3 0 Caspase recruitment domain GAT PF03127.14 GAM43659.1 - 7.2 7.0 6.8 8.6 6.8 0.4 3.9 3 1 1 4 4 4 0 GAT domain PhyH PF05721.13 GAM43660.1 - 2.8e-26 93.1 0.1 3.7e-25 89.4 0.1 2.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UNC-50 PF05216.13 GAM43660.1 - 2.5e-15 56.7 0.2 3.7e-15 56.1 0.2 1.2 1 0 0 1 1 1 1 UNC-50 family PP28 PF10252.9 GAM43661.1 - 8.7e-26 90.2 20.3 8.7e-26 90.2 20.3 3.1 1 1 2 3 3 3 1 Casein kinase substrate phosphoprotein PP28 LAP1C PF05609.12 GAM43661.1 - 5.7 5.9 16.4 7.1 5.6 16.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Lipase_GDSL_2 PF13472.6 GAM43662.1 - 5.4e-13 49.7 0.3 6.6e-13 49.4 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAM43662.1 - 6.6e-08 32.8 0.0 7.8e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ank PF00023.30 GAM43663.1 - 1.2e-15 57.2 1.2 0.0003 21.1 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 GAM43663.1 - 1.7e-15 57.4 0.2 2e-09 37.9 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM43663.1 - 1.2e-13 51.2 1.0 3.9e-10 40.0 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM43663.1 - 9.6e-10 37.9 1.2 0.058 14.0 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat PNP_UDP_1 PF01048.20 GAM43663.1 - 4.9e-08 32.5 0.0 9.1e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily Ank_5 PF13857.6 GAM43663.1 - 8.9e-08 32.3 2.6 0.00022 21.4 0.3 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) NACHT PF05729.12 GAM43663.1 - 3.4e-06 27.1 0.0 7.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAM43663.1 - 0.0011 19.4 0.1 0.0086 16.5 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAM43663.1 - 0.0031 17.8 0.0 0.012 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 GAM43663.1 - 0.071 13.5 0.0 0.41 11.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Aldose_epim PF01263.20 GAM43665.1 - 1.7e-60 204.9 0.1 1.9e-60 204.7 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Zn_clus PF00172.18 GAM43666.1 - 2.5e-08 33.9 12.0 4.1e-08 33.2 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 GAM43667.1 - 1.2e-22 80.3 53.1 2e-22 79.6 49.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF485 PF04341.12 GAM43667.1 - 0.022 14.7 3.5 0.022 14.7 3.5 4.5 3 2 3 6 6 6 0 Protein of unknown function, DUF485 HMGL-like PF00682.19 GAM43669.1 - 9.8e-47 159.7 0.0 1.4e-46 159.2 0.0 1.3 1 0 0 1 1 1 1 HMGL-like ECH_1 PF00378.20 GAM43669.1 - 1.1e-25 90.4 0.0 1.8e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM43669.1 - 3.4e-22 79.4 0.0 6e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase F-box-like PF12937.7 GAM43670.1 - 0.00082 19.2 0.3 0.0019 18.1 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM43670.1 - 0.0012 18.7 2.5 0.0042 16.9 0.4 2.6 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 GAM43670.1 - 0.0016 18.3 0.2 0.0043 16.9 0.2 1.7 1 0 0 1 1 1 1 F-box Pinin_SDK_N PF04697.13 GAM43671.1 - 0.023 15.4 0.2 0.023 15.4 0.2 3.5 1 1 0 3 3 3 0 pinin/SDK conserved region BCA_ABC_TP_C PF12399.8 GAM43671.1 - 0.35 10.8 2.3 4.9 7.2 0.3 2.4 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter VirionAssem_T7 PF11653.8 GAM43672.1 - 0.68 10.5 0.1 0.68 10.5 0.1 2.4 2 1 1 3 3 3 0 Bacteriophage T7 virion assembly protein Cation_efflux PF01545.21 GAM43673.1 - 7.7e-25 87.8 10.9 1.3e-24 87.0 10.9 1.4 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAM43673.1 - 2.6e-05 24.3 0.0 5.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter F-box-like PF12937.7 GAM43674.1 - 0.026 14.4 0.2 0.063 13.2 0.2 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 GAM43674.1 - 0.03 14.2 0.2 0.03 14.2 0.2 1.9 2 0 0 2 2 2 0 F-box domain Ribonuc_L-PSP PF01042.21 GAM43675.1 - 3.8e-39 133.4 0.1 4.2e-39 133.3 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF2529 PF10740.9 GAM43675.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) Abhydrolase_3 PF07859.13 GAM43676.1 - 1.9e-58 197.8 1.4 5.1e-56 189.9 1.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAM43676.1 - 6.9e-10 38.4 0.0 9.8e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 GAM43676.1 - 0.0054 15.6 0.0 0.028 13.3 0.0 2.1 3 0 0 3 3 3 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 GAM43676.1 - 0.0091 15.5 1.0 0.028 13.9 0.1 2.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family Pkinase PF00069.25 GAM43677.1 - 2.2e-63 214.1 0.0 2.9e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM43677.1 - 8.8e-35 120.2 0.0 1.3e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM43677.1 - 3.1e-06 26.2 0.4 1.1e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAM43677.1 - 0.0008 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 GAM43677.1 - 0.02 14.0 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 GAM43677.1 - 0.044 12.7 0.0 0.044 12.7 0.0 1.7 2 1 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 GAM43677.1 - 0.061 12.9 0.7 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 RIO1 family SH2_2 PF14633.6 GAM43678.1 - 1.4e-87 292.7 0.0 4.6e-87 291.0 0.0 2.0 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 GAM43678.1 - 1.2e-36 125.7 1.0 1.2e-36 125.7 1.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 GAM43678.1 - 1.8e-27 95.7 0.0 3.8e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 GAM43678.1 - 4.7e-23 81.6 0.0 4e-22 78.6 0.0 2.6 2 1 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 GAM43678.1 - 7.4e-18 64.9 25.5 7.4e-18 64.9 25.5 6.4 5 2 1 6 6 6 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 GAM43678.1 - 1.2e-07 32.5 3.6 3.9e-06 27.7 3.6 3.3 1 1 0 1 1 1 1 HHH domain SH2 PF00017.24 GAM43678.1 - 5.1e-06 26.5 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 GAM43678.1 - 5.5e-05 23.3 0.0 0.00017 21.8 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tex_N PF09371.10 GAM43678.1 - 0.14 11.8 0.0 0.14 11.8 0.0 3.8 4 0 0 4 4 4 0 Tex-like protein N-terminal domain MFS_1 PF07690.16 GAM43679.1 - 1.6e-26 93.1 19.5 1.6e-26 93.1 19.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily PRT_C PF08372.10 GAM43679.1 - 0.071 12.9 0.4 0.16 11.7 0.4 1.6 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal MFS_1 PF07690.16 GAM43680.1 - 1e-05 24.6 0.1 1.3e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily K-box PF01486.17 GAM43680.1 - 0.28 11.4 1.6 0.31 11.3 0.4 1.6 2 0 0 2 2 2 0 K-box region HpcH_HpaI PF03328.14 GAM43681.1 - 3.8e-34 117.7 0.2 5.1e-34 117.3 0.2 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 GAM43681.1 - 0.00016 20.9 0.1 0.0084 15.3 0.1 2.7 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain Ribonuc_L-PSP PF01042.21 GAM43682.1 - 2.4e-22 79.2 0.0 3e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP 2OG-FeII_Oxy PF03171.20 GAM43683.1 - 2.4e-12 47.2 0.0 5e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 GAM43683.1 - 1.9e-10 41.5 0.0 4.7e-10 40.3 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Fungal_trans PF04082.18 GAM43684.1 - 2.4e-18 66.1 1.3 5.2e-18 65.0 1.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAM43684.1 - 4.9e-07 29.9 12.1 3.5e-05 24.0 0.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAM43684.1 - 2.4e-06 27.9 13.6 0.0039 17.9 0.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 GAM43684.1 - 2.4e-05 24.6 4.0 0.053 13.9 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 GAM43684.1 - 0.044 14.2 8.5 0.12 12.8 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 GAM43684.1 - 0.19 12.1 4.5 9.2 6.7 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAM43684.1 - 0.66 10.3 6.9 21 5.5 1.9 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) ABM PF03992.16 GAM43685.1 - 0.0075 16.4 1.2 0.06 13.5 0.6 2.5 2 1 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Fungal_trans PF04082.18 GAM43686.1 - 2.8e-07 29.8 0.0 5.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Oxysterol_BP PF01237.18 GAM43687.1 - 9.3e-115 383.4 0.0 1.7e-114 382.6 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Transp_cyt_pur PF02133.15 GAM43687.1 - 8.3e-90 301.7 44.0 1.1e-89 301.3 44.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PH_8 PF15409.6 GAM43687.1 - 6.9e-38 128.8 0.1 1.7e-37 127.5 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 GAM43687.1 - 1.1e-06 29.0 0.0 2.8e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAM43687.1 - 0.14 12.6 0.5 2.6 8.5 0.5 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain SGL PF08450.12 GAM43688.1 - 2.1e-39 135.6 0.0 2.1e-37 129.0 0.0 2.1 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 GAM43688.1 - 0.00074 19.4 0.0 0.0025 17.8 0.0 2.0 1 0 0 1 1 1 1 NHL repeat DUF839 PF05787.13 GAM43688.1 - 0.021 14.0 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) Reg_prop PF07494.11 GAM43688.1 - 0.11 12.8 1.0 1.7 9.1 0.1 3.0 3 0 0 3 3 3 0 Two component regulator propeller IFRD PF05004.13 GAM43689.1 - 9.7e-85 284.3 10.2 1.4e-84 283.9 10.2 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Cnd3 PF12719.7 GAM43689.1 - 1.9e-05 24.0 1.5 4.7e-05 22.7 0.6 1.9 1 1 1 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 GAM43689.1 - 0.011 16.1 0.1 1.5 9.3 0.0 2.9 1 1 1 2 2 2 0 HEAT repeats HEAT PF02985.22 GAM43689.1 - 0.023 14.9 0.1 13 6.4 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat HUN PF08729.10 GAM43690.1 - 3.7e-08 33.3 0.1 7e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.10 GAM43692.1 - 4e-25 87.7 0.0 7.5e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 GAM43692.1 - 8.6e-16 57.5 10.2 1.5e-15 56.7 10.2 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal DUF4085 PF13315.6 GAM43692.1 - 0.33 10.5 1.8 0.54 9.8 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) HGTP_anticodon PF03129.20 GAM43693.1 - 2.1e-23 82.3 0.9 5e-23 81.1 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAM43693.1 - 1.9e-07 31.2 0.0 8.1e-07 29.2 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) adh_short PF00106.25 GAM43695.1 - 4.6e-32 111.1 2.4 4.6e-32 111.1 2.4 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43695.1 - 2.5e-22 79.6 3.2 7.2e-22 78.1 3.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans_2 PF11951.8 GAM43695.1 - 6e-20 71.4 0.1 1.2e-19 70.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 GAM43695.1 - 2.2e-15 56.4 0.0 4.2e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.10 GAM43695.1 - 2.3e-13 50.4 0.2 1.3e-12 48.1 0.3 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAM43695.1 - 0.0044 16.5 1.9 0.042 13.3 0.5 3.0 3 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM43695.1 - 0.061 12.5 0.2 0.1 11.7 0.2 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CAF1A PF12253.8 GAM43695.1 - 0.07 13.3 0.2 0.19 11.9 0.2 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A tRNA-synt_1b PF00579.25 GAM43696.1 - 8.8e-53 179.5 0.0 1.1e-52 179.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ANAPC1 PF12859.7 GAM43697.1 - 1e-30 107.0 0.5 1e-30 107.0 0.5 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 GAM43697.1 - 0.26 11.8 8.0 1.3 9.6 0.0 4.2 4 0 0 4 4 4 0 Proteasome/cyclosome repeat SKG6 PF08693.10 GAM43698.1 - 4.9e-08 32.3 1.2 1e-07 31.2 1.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 GAM43698.1 - 0.005 16.7 1.3 0.019 14.8 1.3 2.1 1 0 0 1 1 1 1 TMEM154 protein family DAG1 PF05454.11 GAM43698.1 - 0.053 12.9 0.2 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4448 PF14610.6 GAM43698.1 - 0.053 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Peptidase_M56 PF05569.11 GAM43698.1 - 0.14 11.3 0.2 0.26 10.5 0.2 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 UBA2_C PF16195.5 GAM43698.1 - 0.79 10.5 7.7 0.051 14.3 1.6 2.2 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus p450 PF00067.22 GAM43699.1 - 1.5e-58 198.7 0.0 2e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 eIF2A PF08662.11 GAM43700.1 - 3.5e-81 271.7 0.0 2.3e-80 269.1 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 GAM43700.1 - 0.0012 19.6 1.2 0.12 13.3 0.1 4.1 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM43700.1 - 0.014 15.7 0.0 38 4.7 0.0 4.8 4 1 2 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 GAM43700.1 - 0.027 13.0 0.0 0.049 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain PD40 PF07676.12 GAM43700.1 - 0.071 13.1 0.6 42 4.2 0.1 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat SOG2 PF10428.9 GAM43700.1 - 0.14 11.3 1.3 0.19 10.9 1.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein IKI3 PF04762.12 GAM43700.1 - 0.17 9.9 0.0 0.28 9.1 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Acetyltransf_13 PF13880.6 GAM43703.1 - 3.1e-26 91.2 0.0 1.2e-25 89.2 0.0 2.0 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 GAM43703.1 - 3.6e-13 49.1 0.1 8.1e-13 48.0 0.1 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO EMG1 PF03587.14 GAM43704.1 - 4.3e-80 268.0 0.0 5e-80 267.8 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase RP854 PF17460.2 GAM43704.1 - 0.009 15.8 0.0 0.019 14.8 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized protein RP854 Glyoxalase PF00903.25 GAM43705.1 - 0.01 16.0 0.1 0.034 14.3 0.0 1.9 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Rick_17kDa_Anti PF05433.15 GAM43705.1 - 0.24 11.3 2.2 0.55 10.1 2.2 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain UQ_con PF00179.26 GAM43706.1 - 7.4e-52 174.7 0.0 8.3e-52 174.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAM43706.1 - 0.049 13.9 0.0 0.059 13.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 GAM43706.1 - 0.059 13.2 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 GAM43706.1 - 0.076 12.7 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B Acyl-CoA_dh_N PF02771.16 GAM43707.1 - 1.5e-26 93.2 0.1 3.2e-26 92.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 GAM43707.1 - 1.3e-24 87.1 0.2 2.5e-24 86.2 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAM43707.1 - 8.6e-16 57.9 0.0 1.6e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAM43707.1 - 9.8e-07 29.1 0.5 9.8e-07 29.1 0.5 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain NAD_binding_6 PF08030.12 GAM43708.1 - 3.1e-33 115.1 0.0 4.6e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAM43708.1 - 7.2e-21 74.3 0.0 1.8e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 GAM43708.1 - 4.6e-13 49.4 10.3 4.6e-13 49.4 10.3 2.2 1 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 GAM43708.1 - 0.064 13.9 0.0 0.29 11.8 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain He_PIG_assoc PF10632.9 GAM43709.1 - 0.069 12.8 0.1 3.6 7.3 0.0 2.9 3 0 0 3 3 3 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Zn_clus PF00172.18 GAM43710.1 - 5.8e-09 35.9 12.0 1e-08 35.2 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM43710.1 - 4.3e-06 25.9 1.1 8.3e-06 25.0 1.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Alpha-amylase PF00128.24 GAM43711.1 - 6.1e-110 367.9 1.0 4.2e-109 365.2 1.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 GAM43711.1 - 0.0053 16.8 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 GAM43711.1 - 0.011 14.9 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Sugar_tr PF00083.24 GAM43712.1 - 3e-88 296.7 22.9 3.4e-88 296.5 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM43712.1 - 4.9e-21 75.0 52.4 5.6e-19 68.3 26.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM43712.1 - 2.2e-05 23.2 21.0 0.0017 17.0 2.8 3.0 2 1 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 GAM43712.1 - 0.0014 17.6 9.2 0.011 14.6 3.5 2.2 2 0 0 2 2 2 2 MFS_1 like family Ndc1_Nup PF09531.10 GAM43712.1 - 1.3 7.6 3.7 2.3 6.8 3.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup OppC_N PF12911.7 GAM43712.1 - 2.7 8.0 8.0 1.6 8.8 0.5 2.9 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Glyco_hydro_49N PF17433.2 GAM43713.1 - 3.5e-93 310.5 1.9 3.5e-93 310.5 1.9 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 49 N-terminal Ig-like domain Glyco_hydro_49 PF03718.13 GAM43713.1 - 8.5e-44 148.3 0.4 1.7e-43 147.3 0.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 B_solenoid_dext PF18841.1 GAM43713.1 - 2.9e-17 62.6 4.2 7.6e-17 61.3 4.2 1.8 1 0 0 1 1 1 1 Beta solenoid repeat from Dextranase IPU_b_solenoid PF18783.1 GAM43713.1 - 4.8e-14 52.1 0.6 1e-13 51.1 0.6 1.6 1 0 0 1 1 1 1 Isopullulanase beta-solenoid repeat adh_short PF00106.25 GAM43714.1 - 1.5e-37 128.9 0.0 2.1e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43714.1 - 2.3e-26 92.8 0.1 3e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 GAM43714.1 - 8.4e-07 28.8 0.1 1.4e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM43714.1 - 4.9e-06 26.5 0.0 9.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 GAM43714.1 - 8.3e-05 22.1 0.0 0.0023 17.4 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 GAM43714.1 - 0.0001 21.9 0.1 0.0014 18.1 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAM43714.1 - 0.0022 17.9 0.3 0.0038 17.2 0.1 1.6 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 GAM43714.1 - 0.0061 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 GAM43714.1 - 0.0091 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain DNA_pol_lambd_f PF10391.9 GAM43714.1 - 0.0099 15.7 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda NAD_binding_2 PF03446.15 GAM43714.1 - 0.086 13.0 0.0 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 GAM43714.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.17 GAM43714.1 - 0.16 11.0 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain PPTA PF01239.22 GAM43715.1 - 0.11 12.3 0.1 0.42 10.4 0.1 2.0 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat Zn_clus PF00172.18 GAM43716.1 - 8.3e-09 35.4 7.8 1.3e-08 34.8 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM43716.1 - 4.3e-05 22.7 0.2 0.0001 21.5 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain XPG_I PF00867.18 GAM43717.1 - 3e-32 110.8 1.3 1.9e-31 108.3 0.0 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 GAM43717.1 - 1.2e-30 105.9 0.3 5.9e-30 103.7 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 GAM43717.1 - 3.2e-06 27.6 0.6 1.9e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 GAM43717.1 - 0.038 14.6 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_2 PF12826.7 GAM43717.1 - 0.099 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Muted PF14942.6 GAM43717.1 - 0.84 10.0 9.6 2.8 8.3 1.3 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Linker_histone PF00538.19 GAM43718.1 - 2.5e-31 107.9 0.5 6.6e-31 106.5 0.5 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family PIP5K PF01504.18 GAM43719.1 - 5e-101 337.5 0.0 9.9e-101 336.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Fungal_trans PF04082.18 GAM43720.1 - 0.051 12.6 0.1 0.082 11.9 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 GAM43721.1 - 1e-29 103.9 0.0 1.5e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM43721.1 - 2e-05 25.3 0.2 3.9e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 GAM43721.1 - 0.02 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family FSH1 PF03959.13 GAM43721.1 - 0.036 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 GAM43721.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family AXE1 PF05448.12 GAM43721.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 GAM43721.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PNP_UDP_1 PF01048.20 GAM43722.1 - 5e-09 35.8 0.1 8.1e-08 31.8 0.1 2.4 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 GAM43723.1 - 3.6e-21 75.6 0.0 2.4e-14 53.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM43723.1 - 1.7e-18 64.7 0.0 0.00013 22.1 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 GAM43723.1 - 5.3e-15 55.1 0.0 0.0013 19.1 0.0 4.3 4 0 0 4 4 3 3 Ankyrin repeat Ank_4 PF13637.6 GAM43723.1 - 5.3e-13 49.2 0.0 2.4e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM43723.1 - 3.1e-09 36.9 0.0 0.054 13.8 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) zf-C2H2 PF00096.26 GAM43723.1 - 5.6e-05 23.4 13.8 0.15 12.5 0.2 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type DUF1101 PF06503.11 GAM43723.1 - 0.0012 18.2 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1101) DUF4451 PF14616.6 GAM43723.1 - 0.025 14.8 1.8 0.056 13.7 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Pox_G9-A16 PF03003.16 GAM43723.1 - 0.069 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 FOXP-CC PF16159.5 GAM43723.1 - 0.075 13.7 5.2 1.1 10.0 1.1 3.3 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 GAM43723.1 - 6.1 8.0 18.5 0.97 10.5 0.3 4.3 5 0 0 5 5 4 0 C2H2-type zinc finger PEP_mutase PF13714.6 GAM43724.1 - 3.2e-60 203.5 3.0 5e-60 202.9 3.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase MTD PF01993.18 GAM43724.1 - 0.058 12.7 0.6 4.6 6.5 0.2 2.1 2 0 0 2 2 2 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase TFIID_20kDa PF03847.13 GAM43726.1 - 4.5e-21 75.1 0.0 7.3e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 GAM43726.1 - 0.057 13.8 0.0 0.057 13.8 0.0 3.1 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 PI3K_C2 PF00792.24 GAM43726.1 - 0.088 12.7 0.5 0.18 11.8 0.5 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 TLP-20 PF06088.11 GAM43726.1 - 0.14 12.1 0.4 0.26 11.2 0.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Allexi_40kDa PF05549.11 GAM43726.1 - 0.33 10.4 6.0 0.72 9.3 6.0 1.6 1 0 0 1 1 1 0 Allexivirus 40kDa protein DASH_Spc34 PF08657.10 GAM43727.1 - 4.2e-42 144.7 9.9 9.2e-23 81.3 0.2 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 HEPN_DZIP3 PF18738.1 GAM43727.1 - 0.016 14.9 0.2 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 DZIP3/ hRUL138-like HEPN DASH_Spc19 PF08287.11 GAM43727.1 - 1.4 8.8 6.6 0.15 11.9 1.9 1.7 2 0 0 2 2 2 0 Spc19 Uds1 PF15456.6 GAM43727.1 - 2.7 8.2 7.4 0.95 9.6 3.6 2.1 2 1 0 2 2 2 0 Up-regulated During Septation Rpn3_C PF08375.11 GAM43728.1 - 5.1e-25 87.7 0.9 5.1e-25 87.7 0.9 2.4 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 GAM43728.1 - 8.7e-19 68.0 0.1 7.9e-18 64.9 0.0 2.5 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 GAM43728.1 - 0.039 14.1 0.0 0.15 12.3 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 GAM43728.1 - 0.063 13.3 0.3 0.8 9.7 0.1 2.6 2 1 0 2 2 2 0 CSN8/PSMD8/EIF3K family SOG2 PF10428.9 GAM43728.1 - 4.5 6.4 8.8 6.4 5.9 8.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 GAM43728.1 - 7 5.1 6.4 11 4.5 6.4 1.2 1 0 0 1 1 1 0 Macoilin family polyprenyl_synt PF00348.17 GAM43730.1 - 8.1e-72 241.3 0.0 2.1e-71 240.0 0.0 1.6 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 GAM43730.1 - 0.003 17.2 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 SAICAR_synt PF01259.18 GAM43731.1 - 7.7e-99 330.4 0.0 8.9e-99 330.2 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase ANAPC5 PF12862.7 GAM43732.1 - 1e-35 121.7 3.1 1e-35 121.7 3.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 GAM43732.1 - 8.8e-06 25.4 0.3 0.00066 19.5 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM43732.1 - 5.5e-05 23.4 5.2 0.092 13.0 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM43732.1 - 0.0019 18.2 0.3 0.059 13.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM43732.1 - 0.0022 18.5 0.2 1.9 9.1 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM43732.1 - 0.014 15.3 0.1 0.88 9.8 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAM43732.1 - 0.018 15.7 0.3 0.27 11.9 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM43732.1 - 0.058 13.5 0.1 0.39 11.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Aegerolysin PF06355.13 GAM43733.1 - 6.3e-36 123.3 0.5 7.8e-36 123.0 0.5 1.0 1 0 0 1 1 1 1 Aegerolysin ATP-grasp_2 PF08442.10 GAM43734.1 - 1.9e-52 177.8 0.0 2.6e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 GAM43734.1 - 9.9e-09 35.0 0.0 1.9e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 GAM43734.1 - 7.7e-07 29.1 0.2 1.7e-06 27.9 0.1 1.6 2 0 0 2 2 2 1 CoA-ligase CIA30 PF08547.12 GAM43735.1 - 1.5e-39 135.5 0.0 7.9e-26 91.0 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Cation_ATPase_N PF00690.26 GAM43735.1 - 0.024 14.3 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus GSH-S_ATP PF02955.16 GAM43736.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain PhyH PF05721.13 GAM43737.1 - 6.5e-07 29.8 0.3 5.9e-06 26.7 0.3 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3425 PF11905.8 GAM43738.1 - 6.5e-07 29.4 0.1 1.3e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) SOG2 PF10428.9 GAM43738.1 - 0.0021 17.4 8.4 0.003 16.8 8.4 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein adh_short PF00106.25 GAM43739.1 - 8.4e-25 87.4 0.6 5.2e-20 71.7 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43739.1 - 3.6e-14 52.9 0.2 6.5e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM43739.1 - 8.8e-08 32.3 0.1 1.5e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 GAM43739.1 - 0.058 12.6 0.4 0.25 10.5 0.2 2.2 2 1 0 2 2 2 0 Male sterility protein Toprim_4 PF13662.6 GAM43739.1 - 0.13 12.7 0.1 0.5 10.9 0.1 2.1 1 1 0 1 1 1 0 Toprim domain adh_short PF00106.25 GAM43741.1 - 8.3e-26 90.6 0.0 1.4e-25 89.9 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43741.1 - 1.4e-19 70.6 0.8 6.7e-19 68.4 0.8 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM43741.1 - 5.4e-07 29.7 1.2 6.7e-06 26.1 0.1 2.2 2 0 0 2 2 2 1 KR domain Methyltransf_25 PF13649.6 GAM43741.1 - 0.11 13.2 0.1 0.33 11.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 GAM43741.1 - 0.19 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Eno-Rase_NADH_b PF12242.8 GAM43741.1 - 0.34 10.7 1.1 0.72 9.6 1.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pup PF05639.11 GAM43742.1 - 2.8e-08 34.6 0.2 4.6e-08 33.8 0.2 1.3 1 0 0 1 1 1 1 Pup-like protein YecM PF06185.12 GAM43742.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 YecM protein SesA PF17107.5 GAM43743.1 - 1.5e-36 125.3 0.1 4.6e-36 123.7 0.1 1.9 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_12 PF13424.6 GAM43743.1 - 1.6e-15 57.2 0.4 1.7e-14 53.8 0.5 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM43743.1 - 1.4e-11 43.9 0.9 0.00019 21.2 0.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.22 GAM43743.1 - 6.4e-08 32.1 0.0 0.00057 19.1 0.0 2.5 1 1 1 2 2 2 2 NB-ARC domain TPR_MalT PF17874.1 GAM43743.1 - 1.8e-05 24.3 1.2 3e-05 23.6 1.2 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_1 PF00515.28 GAM43743.1 - 2e-05 24.2 3.9 0.0002 21.1 0.6 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.6 GAM43743.1 - 0.00037 20.9 0.7 0.0015 18.9 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain TPR_2 PF07719.17 GAM43743.1 - 0.00046 20.1 4.4 0.002 18.1 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM43743.1 - 0.00062 20.4 3.7 0.11 13.3 0.1 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 GAM43743.1 - 0.0018 18.0 0.3 0.0035 17.1 0.3 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 GAM43743.1 - 0.0037 17.2 0.2 0.16 12.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat IstB_IS21 PF01695.17 GAM43743.1 - 0.01 15.6 0.1 0.042 13.6 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein TPR_11 PF13414.6 GAM43743.1 - 0.01 15.5 0.2 0.025 14.3 0.2 1.7 1 0 0 1 1 1 0 TPR repeat TPR_8 PF13181.6 GAM43743.1 - 0.014 15.6 2.1 0.11 12.7 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAM43743.1 - 0.022 15.4 4.1 0.18 12.5 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ATPase_2 PF01637.18 GAM43743.1 - 0.028 14.3 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Phage_T4_Ndd PF06591.11 GAM43743.1 - 0.15 11.9 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) TPR_19 PF14559.6 GAM43743.1 - 1.4 9.4 5.8 0.57 10.7 1.7 2.4 2 1 1 3 3 2 0 Tetratricopeptide repeat Glyco_hydro_18 PF00704.28 GAM43745.1 - 1.8e-14 54.2 2.0 5.2e-14 52.7 2.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 GST_N_3 PF13417.6 GAM43746.1 - 2.7e-10 40.5 0.1 8.4e-10 38.9 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM43746.1 - 2.5e-07 30.9 0.0 6.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM43746.1 - 0.00011 22.4 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM43746.1 - 0.00011 22.3 0.0 0.00027 21.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GAM43746.1 - 0.00085 19.5 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 GAM43746.1 - 0.0043 17.0 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM43746.1 - 0.0096 16.2 0.0 0.86 10.0 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain SQHop_cyclase_N PF13249.6 GAM43746.1 - 0.024 13.7 0.0 0.053 12.6 0.0 1.5 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain bZIP_1 PF00170.21 GAM43747.1 - 4.9e-07 29.8 8.2 5.4e-07 29.6 6.6 1.9 1 1 1 2 2 2 1 bZIP transcription factor MSA-2c PF12238.8 GAM43747.1 - 0.14 12.1 4.4 3.4 7.6 0.0 2.1 1 1 1 2 2 2 0 Merozoite surface antigen 2c bZIP_2 PF07716.15 GAM43747.1 - 0.15 12.2 10.4 0.32 11.1 10.4 1.7 1 1 0 1 1 1 0 Basic region leucine zipper Fungal_trans_2 PF11951.8 GAM43748.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short_C2 PF13561.6 GAM43749.1 - 3.6e-65 219.8 0.8 4.1e-65 219.6 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM43749.1 - 3.9e-47 160.2 1.3 4.9e-47 159.9 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM43749.1 - 5.7e-12 45.9 0.6 7.8e-12 45.5 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM43749.1 - 4.9e-05 22.9 0.2 0.00011 21.8 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 GAM43749.1 - 0.033 13.6 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 GAM43749.1 - 0.034 13.5 0.9 0.062 12.6 0.1 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TF_AP-2 PF03299.14 GAM43749.1 - 0.086 12.8 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Transcription factor AP-2 AdoHcyase_NAD PF00670.21 GAM43749.1 - 0.14 12.2 2.8 0.53 10.3 2.8 1.9 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Eno-Rase_NADH_b PF12242.8 GAM43749.1 - 0.18 11.6 1.3 0.65 9.8 1.3 1.9 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GMC_oxred_N PF00732.19 GAM43750.1 - 4e-65 220.1 0.0 5.9e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM43750.1 - 9.5e-31 107.3 0.0 1.6e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAM43750.1 - 1.2e-05 24.6 1.0 3.2e-05 23.1 0.4 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAM43750.1 - 2.6e-05 23.5 1.9 0.00024 20.3 1.9 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM43750.1 - 5.1e-05 23.4 0.3 0.00013 22.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM43750.1 - 0.00076 18.8 0.0 0.094 12.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM43750.1 - 0.0016 17.8 0.1 0.0036 16.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAM43750.1 - 0.0039 16.5 0.1 0.01 15.1 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM43750.1 - 0.0047 16.6 4.5 0.028 14.0 4.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM43750.1 - 0.0058 15.4 0.7 0.011 14.5 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 GAM43750.1 - 0.091 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAM43750.1 - 0.1 13.2 0.0 1.5 9.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 GAM43751.1 - 8.2e-18 64.7 0.0 8.7e-14 51.5 0.0 3.0 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM43751.1 - 1.5e-06 27.7 0.0 3.7e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 GAM43751.1 - 0.093 12.3 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Fungal_trans_2 PF11951.8 GAM43752.1 - 0.00032 19.6 0.2 0.0013 17.6 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Hemerythrin PF01814.23 GAM43753.1 - 2.9e-12 47.3 0.2 4.1e-12 46.9 0.2 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Abhydrolase_6 PF12697.7 GAM43754.1 - 8.1e-10 39.7 0.0 9.9e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM43754.1 - 3.8e-07 29.6 0.0 5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM43754.1 - 9.6e-07 28.7 0.0 1.8e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 GAM43754.1 - 0.00093 19.4 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF2920 PF11144.8 GAM43754.1 - 0.0011 18.2 0.0 0.0014 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Lipase_3 PF01764.25 GAM43754.1 - 0.013 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 GAM43754.1 - 0.015 15.2 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 GAM43754.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.12 GAM43754.1 - 0.029 14.0 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_5 PF12695.7 GAM43754.1 - 0.086 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 GAM43754.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF676 PF05057.14 GAM43754.1 - 0.16 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ank_4 PF13637.6 GAM43755.1 - 3.9e-33 113.4 0.1 1.8e-07 31.6 0.0 7.9 6 1 2 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM43755.1 - 2.4e-29 101.7 0.0 2.6e-06 27.9 0.0 5.2 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM43755.1 - 1.8e-23 80.1 3.9 0.0034 17.7 0.0 10.8 10 1 1 11 11 11 4 Ankyrin repeat Ank PF00023.30 GAM43755.1 - 6.8e-21 73.7 2.0 0.0043 17.4 0.0 9.6 9 2 1 10 10 10 3 Ankyrin repeat Ank_5 PF13857.6 GAM43755.1 - 3.3e-18 65.5 1.9 3e-06 27.4 0.0 6.8 6 2 2 8 8 8 3 Ankyrin repeats (many copies) F-box-like PF12937.7 GAM43755.1 - 0.0026 17.6 1.5 0.0032 17.3 0.3 1.8 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 GAM43755.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 F-box DUF2478 PF10649.9 GAM43755.1 - 0.08 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) F-box PF00646.33 GAM43755.1 - 0.14 12.1 0.3 0.28 11.1 0.3 1.5 1 0 0 1 1 1 0 F-box domain p450 PF00067.22 GAM43756.1 - 5.2e-58 196.9 0.0 6.3e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SRP72 PF08492.12 GAM43756.1 - 0.23 11.9 1.2 1.3 9.5 0.2 2.5 3 0 0 3 3 3 0 SRP72 RNA-binding domain MFS_1 PF07690.16 GAM43757.1 - 0.0017 17.4 10.3 0.0017 17.4 10.3 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Claudin_2 PF13903.6 GAM43757.1 - 2.4 7.9 11.7 9.7 5.9 1.3 3.7 4 0 0 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction Med12 PF09497.10 GAM43759.1 - 1.7e-27 95.5 0.0 4.5e-27 94.1 0.0 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 GAM43759.1 - 0.00075 18.5 0.1 0.0093 14.9 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic Mediator 12 subunit domain VIR_N PF15912.5 GAM43759.1 - 0.038 13.6 2.6 0.069 12.7 2.6 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal UPF0139 PF03669.13 GAM43760.1 - 2.9e-07 30.2 0.3 3.8e-07 29.9 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) 7tm_2 PF00002.24 GAM43760.1 - 0.064 12.5 0.0 0.076 12.3 0.0 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) SUI1 PF01253.22 GAM43761.1 - 3.1e-28 98.1 3.6 4.1e-28 97.7 3.6 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 GAM43761.1 - 0.081 13.2 0.4 0.13 12.5 0.4 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain EOS1 PF12326.8 GAM43762.1 - 2.7e-13 50.2 9.2 2.7e-13 50.2 9.2 1.7 1 1 0 2 2 2 1 N-glycosylation protein MBA1 PF07961.11 GAM43763.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 MBA1-like protein MFS_1 PF07690.16 GAM43764.1 - 7.1e-50 169.9 30.9 2.4e-36 125.4 13.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAM43764.1 - 8.8e-09 34.2 3.3 8.8e-09 34.2 3.3 2.4 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 GAM43764.1 - 3.2e-08 32.6 5.3 3.2e-08 32.6 5.3 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 GAM43764.1 - 1.1e-05 24.5 3.5 1.1e-05 24.5 3.5 2.6 1 1 1 2 2 2 1 MFS_1 like family MFS_3 PF05977.13 GAM43764.1 - 2e-05 23.2 12.0 0.0029 16.1 1.7 2.4 2 1 0 2 2 2 2 Transmembrane secretion effector PTR2 PF00854.21 GAM43764.1 - 0.0014 17.5 1.5 0.3 9.9 0.6 2.2 2 0 0 2 2 2 2 POT family RhoGAP PF00620.27 GAM43765.1 - 5.9e-51 172.3 0.0 2e-50 170.6 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 GAM43765.1 - 1.9e-10 40.8 0.3 1.9e-10 40.8 0.3 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DUF3135 PF11333.8 GAM43765.1 - 0.11 12.7 0.5 11 6.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) GIDA_assoc PF13932.6 GAM43765.1 - 0.18 11.9 6.1 0.36 11.0 6.1 1.4 1 0 0 1 1 1 0 GidA associated domain Zn_clus PF00172.18 GAM43766.1 - 6.9e-07 29.3 10.3 1.2e-06 28.6 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM43766.1 - 0.041 12.9 0.1 0.098 11.7 0.1 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ras PF00071.22 GAM43767.1 - 1.6e-54 183.9 0.0 1.9e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM43767.1 - 1.7e-20 73.4 0.0 2.5e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM43767.1 - 9.7e-08 31.7 0.0 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM43767.1 - 0.02 14.5 0.0 0.047 13.2 0.0 1.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RRM_1 PF00076.22 GAM43768.1 - 3.7e-13 49.1 0.0 8.8e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.6 GAM43769.1 - 2.3e-20 73.1 0.0 3.8e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM43769.1 - 1.3e-09 38.7 0.0 8.1e-08 32.9 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM43769.1 - 1.7e-08 35.0 0.0 4.8e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM43769.1 - 3e-08 33.6 0.0 3.2e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM43769.1 - 9.1e-05 23.0 0.0 0.00021 21.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAM43769.1 - 0.014 14.9 0.6 0.079 12.4 0.0 2.4 3 0 0 3 3 3 0 Putative methyltransferase MTS PF05175.14 GAM43769.1 - 0.032 13.8 0.0 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain UPF0146 PF03686.13 GAM43769.1 - 0.063 13.2 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) CMS1 PF14617.6 GAM43770.1 - 2.4e-72 243.3 10.7 3.3e-72 242.9 10.7 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 GAM43770.1 - 2.9e-07 30.4 0.1 3.4e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Tim54 PF11711.8 GAM43770.1 - 1.4 7.6 11.0 1.9 7.2 11.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 GAM43770.1 - 6.8 5.8 5.1 7.7 5.6 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CENP-T_C PF15511.6 GAM43771.1 - 7.2e-47 158.0 0.0 1.1e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAM43771.1 - 2.6e-08 34.1 0.1 4.6e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 GAM43771.1 - 0.00092 19.6 2.1 0.00097 19.5 0.0 2.1 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAM43771.1 - 0.088 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SURF1 PF02104.15 GAM43772.1 - 5.3e-45 153.8 0.0 8.8e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 SURF1 family UBX PF00789.20 GAM43774.1 - 1.3e-11 44.6 0.0 2.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 UBX domain TFIIA PF03153.13 GAM43774.1 - 0.13 12.3 22.8 0.01 15.8 17.3 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Synaphin PF05835.12 GAM43774.1 - 0.7 10.2 18.1 1.6 9.0 18.1 1.6 1 0 0 1 1 1 0 Synaphin protein Tho2 PF11262.8 GAM43774.1 - 4.8 6.3 10.6 8.4 5.5 10.6 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF2076 PF09849.9 GAM43775.1 - 4.1e-09 36.9 12.0 5.3e-09 36.5 12.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 GAM43775.1 - 2.7e-05 24.2 2.2 4.1e-05 23.6 2.2 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 GAM43775.1 - 0.019 15.0 0.5 0.031 14.3 0.5 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Bindin PF02084.15 GAM43775.1 - 0.22 11.8 3.9 0.27 11.5 3.5 1.4 1 1 0 1 1 1 0 Bindin Sporozoite_P67 PF05642.11 GAM43775.1 - 2.4 6.2 7.0 2.8 5.9 7.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sas10_Utp3 PF04000.15 GAM43776.1 - 4.5e-18 65.6 1.0 4.5e-18 65.6 1.0 2.9 3 2 0 3 3 3 1 Sas10/Utp3/C1D family ApbA_C PF08546.11 GAM43777.1 - 1.5e-33 115.6 0.5 2.2e-33 115.1 0.5 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 GAM43777.1 - 4.3e-20 71.9 0.0 8.2e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA SET PF00856.28 GAM43778.1 - 1.4e-14 54.9 0.0 2.3e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 SET domain Methyltransf_24 PF13578.6 GAM43778.1 - 5.9e-12 46.5 0.0 1.8e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 GAM43778.1 - 7.4e-10 38.4 0.0 1.3e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase CmcI PF04989.12 GAM43778.1 - 0.029 14.0 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Oxidored_FMN PF00724.20 GAM43780.1 - 8.7e-98 327.7 0.0 1e-97 327.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 GAM43780.1 - 0.012 15.0 0.0 2.6 7.4 0.0 2.8 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel TrkH PF02386.16 GAM43781.1 - 3.4e-92 309.5 1.6 5.2e-86 289.1 0.3 2.6 2 1 0 2 2 2 2 Cation transport protein Coq4 PF05019.13 GAM43782.1 - 3.1e-95 317.7 0.0 3.8e-95 317.4 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DUF2236 PF09995.9 GAM43782.1 - 0.058 13.6 0.2 0.1 12.8 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) dsDNA_bind PF01984.20 GAM43783.1 - 1.1e-39 135.1 9.3 1.3e-39 134.9 9.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.6 GAM43783.1 - 0.0062 17.1 0.2 0.008 16.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4615) DUF2526 PF10735.9 GAM43783.1 - 4.1 7.6 8.6 1.5 9.0 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) Sec2p PF06428.11 GAM43784.1 - 1.1e-28 99.0 19.8 1.1e-28 99.0 19.8 2.7 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p Macoilin PF09726.9 GAM43784.1 - 0.0026 16.4 19.9 0.0026 16.4 19.9 1.7 2 0 0 2 2 2 1 Macoilin family GCN5L1 PF06320.13 GAM43784.1 - 1.7 8.8 17.0 1.1 9.5 12.1 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF3584 PF12128.8 GAM43784.1 - 2.3 5.6 24.9 3.5 5.0 24.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CorA PF01544.18 GAM43784.1 - 3.2 7.0 8.9 6.1 6.1 8.9 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF5339 PF17274.2 GAM43784.1 - 6.5 7.7 21.1 2.7 8.9 7.9 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5339) ADIP PF11559.8 GAM43784.1 - 6.8 6.8 23.8 4.4 7.4 15.5 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Tup_N PF08581.10 GAM43784.1 - 7.7 6.9 19.7 3.1 8.2 4.5 3.4 2 1 1 3 3 3 0 Tup N-terminal PRP21_like_P PF12230.8 GAM43785.1 - 6.3e-60 202.7 6.2 1.3e-59 201.8 6.2 1.5 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 GAM43785.1 - 4.5e-39 132.2 2.0 5.8e-20 71.0 0.0 2.5 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 GAM43785.1 - 0.0046 16.5 0.2 0.01 15.4 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger PMT PF02366.18 GAM43786.1 - 7.7e-79 264.7 16.4 1.6e-78 263.7 16.4 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAM43786.1 - 2.7e-68 229.5 9.5 2.7e-68 229.5 9.5 2.0 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 GAM43786.1 - 8.3e-48 162.7 0.2 1.9e-47 161.5 0.0 1.7 2 0 0 2 2 2 1 MIR domain RHH_5 PF07878.11 GAM43787.1 - 0.095 12.6 0.2 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Pkinase PF00069.25 GAM43788.1 - 6.3e-18 65.1 0.1 5.4e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM43788.1 - 3.2e-06 26.6 0.0 3.4e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM43788.1 - 0.0073 16.3 0.3 0.036 14.0 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Glyco_hydro_2_C PF02836.17 GAM43789.1 - 0.003 16.7 0.0 0.0051 16.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Alpha_L_fucos PF01120.17 GAM43790.1 - 8.3e-87 291.9 2.7 1.2e-86 291.4 2.7 1.2 1 0 0 1 1 1 1 Alpha-L-fucosidase DHHC PF01529.20 GAM43792.1 - 2.3e-34 118.4 4.7 2.3e-34 118.4 4.7 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.17 GAM43792.1 - 0.025 14.3 0.8 0.025 14.3 0.8 2.2 2 0 0 2 2 2 0 Yip1 domain SET PF00856.28 GAM43793.1 - 6.2e-14 52.7 0.3 6.2e-14 52.7 0.3 4.4 3 3 0 3 3 3 1 SET domain AWS PF17907.1 GAM43793.1 - 1.5e-08 34.6 7.9 1.5e-08 34.6 7.9 1.9 2 0 0 2 2 2 1 AWS domain PBP1_TM PF14812.6 GAM43793.1 - 0.92 9.9 12.7 0.03 14.7 3.2 3.4 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mg_trans_NIPA PF05653.14 GAM43794.1 - 3.1e-75 253.0 10.4 1.4e-66 224.6 3.7 2.0 1 1 1 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 GAM43794.1 - 0.0023 18.1 2.9 0.0023 18.1 2.9 3.6 3 1 0 3 3 3 2 EamA-like transporter family Complex1_LYR PF05347.15 GAM43795.1 - 9.2e-11 41.6 3.2 9.2e-11 41.6 3.2 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAM43795.1 - 0.0017 19.1 1.1 0.0038 18.0 1.1 1.5 1 0 0 1 1 1 1 Complex1_LYR-like NA37 PF04245.13 GAM43795.1 - 0.084 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein PMC2NT PF08066.12 GAM43796.1 - 0.12 13.1 0.0 0.12 13.1 0.0 2.6 2 1 0 2 2 2 0 PMC2NT (NUC016) domain Mucin PF01456.17 GAM43796.1 - 1 9.3 6.9 0.19 11.7 3.4 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein CDC45 PF02724.14 GAM43796.1 - 1.2 7.4 7.7 1.3 7.3 7.7 1.2 1 0 0 1 1 1 0 CDC45-like protein HeLo PF14479.6 GAM43796.1 - 2.8 7.8 7.8 1.1e+02 2.6 7.8 2.5 1 1 0 1 1 1 0 Prion-inhibition and propagation DUF3619 PF12279.8 GAM43798.1 - 0.24 11.7 1.4 0.66 10.3 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) Sugar_tr PF00083.24 GAM43799.1 - 1.8e-130 435.8 27.3 2.1e-130 435.6 27.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM43799.1 - 8.2e-24 84.2 41.3 2.4e-18 66.2 23.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM43799.1 - 3e-05 22.7 10.1 0.0012 17.4 4.5 3.5 3 1 1 4 4 4 2 MFS/sugar transport protein Pox_A14 PF05767.12 GAM43799.1 - 0.012 15.8 2.2 0.19 11.9 0.1 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Methyltransf_11 PF08241.12 GAM43800.1 - 1.5e-15 57.6 0.0 3.3e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM43800.1 - 7.3e-12 45.8 0.0 1.7e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM43800.1 - 2.2e-08 34.1 0.0 4.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Acetyltransf_1 PF00583.25 GAM43800.1 - 1.5e-07 31.7 0.0 3.9e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Methyltransf_12 PF08242.12 GAM43800.1 - 3e-07 31.1 0.0 8.5e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM43800.1 - 1.6e-06 28.0 0.0 3.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM43800.1 - 1.4e-05 24.5 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Acetyltransf_7 PF13508.7 GAM43800.1 - 6.6e-05 23.3 0.0 0.00015 22.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM43800.1 - 0.00013 21.9 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM43800.1 - 0.048 13.6 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein ATP-sulfurylase PF01747.17 GAM43801.1 - 2.3e-87 291.9 0.1 3.5e-87 291.3 0.1 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 GAM43801.1 - 1.5e-59 200.4 0.1 2.4e-59 199.7 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 GAM43801.1 - 4.6e-51 172.6 0.0 7.7e-51 171.9 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.10 GAM43801.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ZZ PF00569.17 GAM43802.1 - 9.4 6.1 7.8 3.7 7.4 0.3 3.4 3 0 0 3 3 3 0 Zinc finger, ZZ type AT_hook PF02178.19 GAM43803.1 - 4.9e-05 22.7 12.2 0.05 13.5 0.2 2.7 2 0 0 2 2 2 2 AT hook motif Eaf7 PF07904.13 GAM43803.1 - 0.32 11.4 5.5 0.62 10.5 2.8 2.7 2 1 0 2 2 2 0 Chromatin modification-related protein EAF7 UPF0449 PF15136.6 GAM43803.1 - 6 7.4 7.1 3.5 8.1 0.0 3.1 3 1 0 3 3 3 0 Uncharacterised protein family UPF0449 Amidohydro_3 PF07969.11 GAM43805.1 - 7.9e-25 88.3 0.2 6.4e-22 78.7 0.3 2.0 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 GAM43805.1 - 6.4e-08 32.3 0.0 8.4e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family MBOAT_2 PF13813.6 GAM43805.1 - 0.0027 18.0 0.2 0.0067 16.7 0.2 1.7 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family 4HBT_3 PF13622.6 GAM43806.1 - 3.8e-45 155.1 0.2 4.5e-45 154.9 0.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Med13_C PF06333.12 GAM43806.1 - 0.027 13.7 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain MFS_1 PF07690.16 GAM43807.1 - 3.7e-19 68.9 35.5 5e-19 68.4 35.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MRP-S35 PF10246.9 GAM43807.1 - 0.09 12.7 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 Atypical_Card PF18461.1 GAM43807.1 - 0.15 12.3 0.8 0.55 10.5 0.1 2.1 2 0 0 2 2 2 0 Atypical caspase recruitment domain Clusterin PF01093.17 GAM43809.1 - 0.00047 19.3 0.2 0.00074 18.7 0.2 1.3 1 0 0 1 1 1 1 Clusterin zf-Di19 PF05605.12 GAM43809.1 - 0.0076 16.5 3.3 0.24 11.7 0.4 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 GAM43809.1 - 0.5 10.9 5.9 6.8 7.3 0.2 3.0 2 0 0 2 2 2 0 Zinc-finger double domain adh_short PF00106.25 GAM43810.1 - 1.7e-11 44.0 0.0 1.8e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43810.1 - 7.1e-07 29.0 0.0 8.1e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAD_binding_3 PF01494.19 GAM43811.1 - 7.8e-11 41.8 3.7 5e-08 32.6 0.5 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAM43811.1 - 2.7e-05 23.9 0.1 9.5e-05 22.1 0.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM43811.1 - 0.014 15.7 1.2 0.03 14.5 0.7 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAM43811.1 - 0.039 14.5 0.2 0.12 13.0 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAM43811.1 - 0.053 12.8 0.2 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 GAM43811.1 - 0.053 12.7 0.1 0.36 10.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PAPS_reduct PF01507.19 GAM43812.1 - 1.6e-44 152.0 0.0 2.2e-43 148.3 0.0 2.0 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.7 GAM43813.1 - 1.5e-25 90.7 0.0 2.4e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM43813.1 - 1.9e-19 70.8 0.6 3.3e-19 70.0 0.6 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAM43813.1 - 2.8e-10 40.4 0.0 9.6e-09 35.3 0.0 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAM43813.1 - 3.7e-06 27.1 0.2 5.2e-05 23.4 0.2 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 GAM43813.1 - 0.00027 20.4 0.0 0.0015 17.9 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase DUF4392 PF14336.6 GAM43813.1 - 0.09 12.2 0.4 2.4 7.5 0.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4392) LIAS_N PF16881.5 GAM43814.1 - 1.3e-23 83.4 0.0 2.9e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 GAM43814.1 - 9.3e-15 55.4 0.0 1.4e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily WD40 PF00400.32 GAM43816.1 - 6.3e-08 33.2 3.6 6.7e-05 23.6 0.1 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM43816.1 - 0.0028 17.9 0.0 4 7.8 0.0 4.0 1 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 GAM43816.1 - 0.0067 16.0 2.0 1 8.9 0.0 3.3 1 1 1 3 3 3 1 PQQ-like domain TMF_TATA_bd PF12325.8 GAM43816.1 - 0.011 15.9 7.7 0.019 15.2 7.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Gryzun-like PF12742.7 GAM43816.1 - 0.021 14.8 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking PQQ_3 PF13570.6 GAM43816.1 - 0.022 15.3 8.7 1.6 9.3 0.5 4.0 3 1 1 4 4 4 0 PQQ-like domain Radial_spoke_3 PF06098.11 GAM43816.1 - 3.6 6.8 11.0 5.6 6.1 11.0 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 DeoC PF01791.9 GAM43817.1 - 1.2e-16 61.1 3.9 1.6e-16 60.7 3.9 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 GAM43817.1 - 6.6e-05 22.3 0.3 0.00012 21.4 0.3 1.5 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 GAM43817.1 - 0.0069 15.9 0.4 0.016 14.7 0.2 1.6 2 0 0 2 2 2 1 Histidine biosynthesis protein Glyco_transf_64 PF09258.10 GAM43818.1 - 0.094 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain Methyltransf_2 PF00891.18 GAM43819.1 - 7.3e-23 81.0 0.0 1.1e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 GAM43819.1 - 3.2e-05 23.8 0.0 7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 GAM43819.1 - 0.0013 18.7 0.1 0.0027 17.7 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain HTH_IclR PF09339.10 GAM43819.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.8 1 1 0 1 1 1 0 IclR helix-turn-helix domain Cu-oxidase_2 PF07731.14 GAM43820.1 - 0.013 15.2 1.1 0.1 12.3 0.6 2.0 1 1 1 2 2 2 0 Multicopper oxidase PDZ_4 PF17816.1 GAM43821.1 - 0.041 14.3 0.1 0.25 11.7 0.0 2.3 2 0 0 2 2 2 0 PDZ domain TSNAXIP1_N PF15739.5 GAM43821.1 - 0.95 9.9 4.4 0.42 11.0 0.3 2.3 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF2235 PF09994.9 GAM43822.1 - 7e-65 219.2 0.0 1.3e-39 136.3 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) F-box-like PF12937.7 GAM43823.1 - 9.4e-06 25.4 0.2 2.4e-05 24.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM43823.1 - 0.033 14.1 2.7 0.041 13.8 0.2 2.4 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 GAM43824.1 - 0.0013 18.6 0.1 0.0035 17.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like TP_methylase PF00590.20 GAM43825.1 - 2.7e-48 164.7 0.0 2.5e-46 158.3 0.0 2.2 2 0 0 2 2 2 2 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 GAM43825.1 - 2.9e-19 69.4 0.0 6.7e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 GAM43825.1 - 6.9e-14 51.2 0.5 7.1e-09 35.2 0.1 2.7 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 GAM43825.1 - 1.1e-07 31.1 0.1 2.7e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central PBP1_TM PF14812.6 GAM43825.1 - 0.61 10.5 4.1 0.21 12.0 1.1 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Abhydrolase_3 PF07859.13 GAM43826.1 - 1.7e-12 47.6 0.0 2.4e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM43826.1 - 2.6e-05 23.8 0.0 0.0044 16.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 GAM43826.1 - 4.4e-05 22.9 0.0 0.00018 20.9 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 GAM43826.1 - 0.0019 16.9 0.0 0.3 9.7 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 GAM43826.1 - 0.011 14.7 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme COesterase PF00135.28 GAM43826.1 - 0.017 14.0 0.0 0.044 12.6 0.0 1.5 2 0 0 2 2 2 0 Carboxylesterase family Esterase PF00756.20 GAM43826.1 - 0.09 12.4 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Abhydrolase_1 PF00561.20 GAM43826.1 - 0.14 11.7 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ceramidase PF05875.12 GAM43827.1 - 3.5e-83 279.1 6.5 4.3e-83 278.8 6.5 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.11 GAM43827.1 - 0.021 14.7 0.9 0.099 12.6 0.9 2.3 1 0 0 1 1 1 0 Trp-operon Leader Peptide Vma12 PF11712.8 GAM43827.1 - 1.9 8.6 5.7 7.1 6.7 2.3 2.3 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PCI PF01399.27 GAM43828.1 - 2.5e-22 79.3 0.0 1.2e-21 77.2 0.0 2.1 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 GAM43828.1 - 4.6e-16 58.6 0.6 1.3e-15 57.2 0.6 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain KORA PF16509.5 GAM43828.1 - 0.041 14.1 0.8 1.8 8.9 0.3 2.8 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor DUF4230 PF14014.6 GAM43828.1 - 7.7 6.8 9.1 1.4 9.2 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF4230) FSH1 PF03959.13 GAM43829.1 - 7.2e-66 221.9 0.0 8.9e-66 221.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 GAM43829.1 - 7.9e-06 26.6 1.3 3.6e-05 24.5 1.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 GAM43829.1 - 0.002 18.3 0.0 0.007 16.5 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain DLH PF01738.18 GAM43829.1 - 0.087 12.4 0.0 5.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Glyco_hydro_99 PF16317.5 GAM43830.1 - 0.088 11.9 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 99 Ribosomal_S27e PF01667.17 GAM43831.1 - 1e-28 98.8 6.7 1.3e-28 98.5 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 GAM43831.1 - 0.26 11.3 6.1 2 8.4 4.2 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type CDP-OH_P_transf PF01066.21 GAM43832.1 - 4.1e-18 65.9 0.2 4.1e-18 65.9 0.2 3.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Putative_PNPOx PF01243.20 GAM43833.1 - 1.9e-12 47.2 0.0 5e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase BPL_LplA_LipB PF03099.19 GAM43834.1 - 0.00014 21.7 0.0 0.00035 20.5 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ras PF00071.22 GAM43835.1 - 5.1e-42 143.2 0.1 6e-42 143.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM43835.1 - 6.4e-13 49.0 0.0 1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM43835.1 - 5.6e-06 25.9 0.0 6.8e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM43835.1 - 0.083 12.2 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AP_endonuc_2 PF01261.24 GAM43836.1 - 5.5e-28 97.8 0.0 1.2e-27 96.8 0.0 1.5 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 GAM43836.1 - 0.0021 17.7 0.0 0.0092 15.7 0.0 2.0 2 0 0 2 2 2 1 AP endonuclease family 2 C terminus CWC25 PF12542.8 GAM43837.1 - 3.3e-26 92.2 0.7 3.3e-26 92.2 0.7 4.0 2 2 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 GAM43837.1 - 3.1e-12 46.5 10.0 3.1e-12 46.5 10.0 3.9 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR PCI PF01399.27 GAM43838.1 - 1.4e-21 77.0 2.0 1.4e-21 77.0 0.5 1.8 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.6 GAM43838.1 - 0.0018 18.2 2.5 0.17 12.0 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM43838.1 - 0.0029 17.4 1.8 0.018 14.8 0.1 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM43838.1 - 0.014 15.4 6.0 0.016 15.2 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM43838.1 - 0.016 15.5 1.0 0.46 10.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM43838.1 - 0.022 14.5 0.1 0.022 14.5 0.1 2.5 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 GAM43838.1 - 0.14 13.0 3.6 1.6 9.8 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM43838.1 - 0.17 12.1 1.7 1.8 9.0 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_C65 PF10275.9 GAM43839.1 - 6e-57 192.9 0.0 7.5e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Ank_2 PF12796.7 GAM43840.1 - 1.8e-19 70.1 0.2 7.7e-10 39.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM43840.1 - 1.7e-18 66.7 6.4 5.1e-07 30.1 0.1 3.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM43840.1 - 6.3e-13 48.7 1.7 3.7e-05 23.9 0.2 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM43840.1 - 1.5e-11 44.1 8.9 0.0044 17.4 0.1 4.6 3 2 1 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 GAM43840.1 - 2.1e-11 43.0 0.4 0.015 15.8 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat MMM1 PF10296.9 GAM43841.1 - 0.00017 20.8 0.0 0.00049 19.3 0.0 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 GAM43841.1 - 0.0026 18.2 0.0 0.012 16.0 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 GAM43841.1 - 0.069 13.7 0.0 0.49 10.9 0.0 2.4 3 0 0 3 3 3 0 PH domain ANTH PF07651.16 GAM43842.1 - 2e-64 217.3 0.0 2e-64 217.3 0.0 3.7 2 2 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 GAM43842.1 - 4.9e-56 189.2 8.1 4.9e-56 189.2 8.1 6.0 4 2 0 6 6 6 1 I/LWEQ domain Pox_F11 PF04943.12 GAM43842.1 - 0.85 8.6 7.0 0.49 9.4 0.2 2.6 2 0 0 2 2 2 0 Poxvirus F11 protein TAF8_C PF10406.9 GAM43842.1 - 1.1 9.9 4.1 3.5 8.3 2.8 2.8 1 1 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term MATalpha_HMGbox PF04769.12 GAM43843.1 - 1.7e-37 128.7 0.0 3.2e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box DUF3316 PF11777.8 GAM43843.1 - 0.04 14.0 0.1 0.063 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) Peptidase_C93 PF06035.11 GAM43843.1 - 0.097 12.5 0.0 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Exo_endo_phos PF03372.23 GAM43845.1 - 7.3e-13 48.6 0.1 1.1e-12 48.0 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 GAM43845.1 - 0.0002 21.4 0.8 0.00046 20.2 0.8 1.7 1 0 0 1 1 1 1 GRF zinc finger COX6A PF02046.15 GAM43846.1 - 4.8e-51 172.0 3.6 5.6e-51 171.7 3.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DJ-1_PfpI PF01965.24 GAM43847.1 - 1.3e-16 60.8 0.0 1.7e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Fungal_trans PF04082.18 GAM43848.1 - 3.3e-26 91.9 1.5 3.4e-26 91.8 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM43848.1 - 5.4e-10 39.2 9.8 9.9e-10 38.4 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 GAM43848.1 - 1.8e-05 24.8 0.0 3.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Gal4-like dimerisation domain Slu7 PF11708.8 GAM43849.1 - 2.1e-81 273.6 20.2 2.1e-81 273.6 20.2 2.7 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 GAM43849.1 - 0.016 14.9 0.4 0.071 12.9 0.6 2.0 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_L37e PF01907.19 GAM43850.1 - 6.2e-28 96.7 11.5 1.2e-27 95.8 11.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e EthD PF07110.11 GAM43850.1 - 1.3e-19 71.1 0.5 2.2e-19 70.4 0.5 1.4 1 0 0 1 1 1 1 EthD domain DZR PF12773.7 GAM43850.1 - 0.044 13.8 1.3 0.077 13.0 1.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon MmlI PF09448.10 GAM43850.1 - 0.093 13.2 0.1 0.29 11.6 0.1 1.8 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase HypA PF01155.19 GAM43850.1 - 0.29 11.2 1.5 0.33 11.0 0.5 1.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF35_N PF12172.8 GAM43850.1 - 0.32 10.9 2.4 0.59 10.1 2.4 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ribbon_3 PF13248.6 GAM43850.1 - 0.63 9.5 2.9 1.7 8.2 2.9 1.7 1 1 0 1 1 1 0 zinc-ribbon domain ATG16 PF08614.11 GAM43851.1 - 0.00019 21.7 10.7 0.00019 21.7 10.7 5.0 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) Bac_globin PF01152.21 GAM43851.1 - 0.0048 17.0 1.0 0.022 14.9 0.0 2.6 3 0 0 3 3 3 1 Bacterial-like globin Spc7 PF08317.11 GAM43851.1 - 1.4 7.7 64.4 0.98 8.2 28.8 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein FAD-oxidase_C PF02913.19 GAM43852.1 - 4.1e-66 223.2 0.0 6e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAM43852.1 - 2.1e-33 115.0 0.0 4.3e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 GAM43852.1 - 0.066 11.9 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Semialdhyde_dhC PF02774.18 GAM43853.1 - 3.4e-34 118.5 0.0 4.7e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 GAM43853.1 - 2.5e-29 102.2 0.0 5.5e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_S4e PF00900.20 GAM43854.1 - 2.7e-37 126.5 0.2 5.7e-37 125.5 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 GAM43854.1 - 1.6e-24 85.2 0.0 2.9e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 GAM43854.1 - 2.5e-17 62.7 5.2 4.7e-17 61.8 5.2 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 GAM43854.1 - 1.2e-06 28.1 0.0 2.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 GAM43854.1 - 0.00015 21.6 2.9 0.00015 21.6 2.9 3.1 4 0 0 4 4 4 1 KOW motif RNase_H PF00075.24 GAM43855.1 - 2.1e-27 96.1 0.0 1.2e-18 67.6 0.0 2.3 2 0 0 2 2 2 2 RNase H RVT_3 PF13456.6 GAM43855.1 - 1.7e-05 24.6 0.1 0.078 12.8 0.0 2.8 3 0 0 3 3 3 2 Reverse transcriptase-like Spc29 PF17082.5 GAM43855.1 - 0.28 11.0 2.8 12 5.6 0.0 2.9 2 1 1 3 3 3 0 Spindle Pole Component 29 RNase_H PF00075.24 GAM43856.1 - 6.6e-23 81.5 0.3 8.5e-23 81.1 0.3 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 GAM43856.1 - 2.3e-08 33.9 0.1 0.00093 19.0 0.1 2.3 2 1 0 2 2 2 2 Reverse transcriptase-like RasGEF PF00617.19 GAM43857.1 - 5.4e-10 39.8 0.6 1.2e-09 38.7 0.6 1.5 1 0 0 1 1 1 1 RasGEF domain Ank_2 PF12796.7 GAM43858.1 - 1.7e-71 236.8 15.8 4.1e-13 49.7 0.1 7.9 3 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM43858.1 - 3.7e-50 167.7 12.5 4.6e-09 36.6 0.0 11.1 8 3 4 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM43858.1 - 5e-50 166.9 17.7 1.3e-10 41.3 0.3 11.9 4 4 8 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 GAM43858.1 - 5.8e-45 149.8 19.6 1.2e-05 25.5 0.2 13.3 13 0 0 13 13 13 10 Ankyrin repeat Ank_3 PF13606.6 GAM43858.1 - 9.6e-40 130.0 15.0 8e-06 25.8 0.1 13.7 15 0 0 15 15 14 7 Ankyrin repeat AAA_22 PF13401.6 GAM43858.1 - 4e-08 33.6 0.0 1.5e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 GAM43858.1 - 8.5e-05 22.5 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAM43858.1 - 9.9e-05 22.8 0.0 0.00039 20.9 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain Helo_like_N PF17111.5 GAM43858.1 - 0.0021 17.4 0.6 0.0045 16.4 0.6 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins ZZ PF00569.17 GAM43858.1 - 0.035 13.9 14.3 0.071 12.9 14.3 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type IstB_IS21 PF01695.17 GAM43858.1 - 0.096 12.4 0.0 2.6 7.7 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Zip PF02535.22 GAM43859.1 - 0.011 14.9 0.6 0.014 14.6 0.2 1.4 1 1 1 2 2 2 0 ZIP Zinc transporter Lyase_aromatic PF00221.19 GAM43860.1 - 6.1e-131 437.3 0.8 9.2e-131 436.7 0.8 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase p450 PF00067.22 GAM43860.1 - 6.7e-36 124.0 0.0 1e-35 123.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.8 GAM43861.1 - 5.9e-92 308.9 0.0 7.5e-92 308.5 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase AMP-binding PF00501.28 GAM43862.1 - 2.7e-16 59.2 0.1 7e-16 57.8 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Abhydrolase_6 PF12697.7 GAM43863.1 - 3.8e-06 27.7 0.2 5.3e-06 27.2 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM43863.1 - 0.03 13.6 0.0 0.06 12.6 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 His_Phos_2 PF00328.22 GAM43864.1 - 8.5e-53 180.1 0.0 1e-52 179.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 GAM43865.1 - 1.2e-15 57.7 0.0 3.1e-14 53.1 0.0 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sugar_tr PF00083.24 GAM43866.1 - 1e-79 268.6 15.8 1.2e-79 268.4 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM43866.1 - 6.9e-12 45.0 28.1 2.2e-08 33.5 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAM43866.1 - 0.083 11.7 9.4 0.045 12.6 3.9 2.3 2 0 0 2 2 2 0 MFS_1 like family Myb_DNA-bind_6 PF13921.6 GAM43867.1 - 7.5e-16 58.1 0.0 4.2e-08 33.3 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAM43867.1 - 4.1e-15 55.7 0.3 2.7e-07 30.7 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain FXR_C1 PF16096.5 GAM43867.1 - 0.0058 16.8 0.2 0.68 10.2 0.3 3.2 2 0 0 2 2 2 1 Fragile X-related 1 protein C-terminal region 2 SLIDE PF09111.10 GAM43867.1 - 0.015 15.3 0.0 5 7.2 0.0 2.5 2 0 0 2 2 2 0 SLIDE PX PF00787.24 GAM43868.1 - 1.1e-27 96.3 0.2 1.3e-27 96.1 0.2 1.1 1 0 0 1 1 1 1 PX domain TAL_FSA PF00923.19 GAM43869.1 - 1.9e-29 103.0 0.0 3.1e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Sugar_tr PF00083.24 GAM43870.1 - 9.1e-87 291.8 12.7 1.1e-86 291.6 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM43870.1 - 8.9e-17 61.0 33.2 6.1e-10 38.5 14.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM43870.1 - 1.6e-06 27.0 9.0 0.0017 17.0 4.0 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 GAM43870.1 - 0.34 9.7 11.0 0.033 13.0 2.1 2.2 2 0 0 2 2 2 0 MFS_1 like family Aldo_ket_red PF00248.21 GAM43871.1 - 3.7e-73 246.3 0.0 4.2e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPP_enzyme_N PF02776.18 GAM43872.1 - 1.1e-56 191.2 0.0 6.8e-56 188.6 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAM43872.1 - 3.3e-49 166.6 0.3 3.5e-48 163.3 0.1 2.8 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAM43872.1 - 4.1e-40 136.7 0.1 7.4e-40 135.9 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 GAM43872.1 - 0.0031 17.3 0.1 0.0059 16.4 0.1 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CO_dh PF02552.16 GAM43872.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit BTB PF00651.31 GAM43873.1 - 0.096 12.9 0.6 0.22 11.8 0.1 1.8 2 0 0 2 2 2 0 BTB/POZ domain DUF2846 PF11008.8 GAM43873.1 - 0.11 12.6 0.0 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2846) adh_short PF00106.25 GAM43874.1 - 4.4e-19 68.7 0.1 1.8e-16 60.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43874.1 - 1.1e-13 51.3 0.1 2.1e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM43874.1 - 0.00021 21.2 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF3073 PF11273.8 GAM43874.1 - 0.026 15.3 0.1 6.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) DRTGG PF07085.12 GAM43874.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 DRTGG domain DUF1749 PF08538.10 GAM43875.1 - 6.7e-93 311.1 0.0 8.6e-93 310.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.20 GAM43875.1 - 0.0021 17.8 0.0 0.0055 16.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM43875.1 - 0.0069 17.0 0.0 0.011 16.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM43875.1 - 0.012 14.8 0.0 0.031 13.6 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 COesterase PF00135.28 GAM43875.1 - 0.028 13.3 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DUF900 PF05990.12 GAM43875.1 - 0.082 12.4 0.0 0.17 11.4 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 GAM43875.1 - 0.098 12.4 0.2 0.5 10.1 0.2 2.2 1 1 0 2 2 2 0 PGAP1-like protein AMP-binding PF00501.28 GAM43876.1 - 3.2e-75 253.3 0.0 3.3e-70 236.8 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 GAM43876.1 - 3.2e-66 223.9 0.0 1.3e-32 113.1 0.0 3.5 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.25 GAM43876.1 - 7.6e-29 99.9 0.2 5.7e-13 49.0 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAM43876.1 - 0.0023 18.9 0.0 4.3 8.4 0.0 3.3 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 GAM43876.1 - 0.053 13.3 0.0 1.5 8.5 0.0 2.7 3 0 0 3 3 3 0 Wax ester synthase-like Acyl-CoA acyltransferase domain ABC_membrane PF00664.23 GAM43877.1 - 4.3e-92 308.6 21.2 8.9e-53 179.7 3.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM43877.1 - 3.3e-63 212.3 0.5 5.4e-30 104.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 GAM43877.1 - 1.6e-14 53.9 6.2 3.5e-05 23.3 0.1 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM43877.1 - 1e-08 34.8 0.4 0.0025 17.5 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM43877.1 - 2.4e-07 31.3 2.3 0.029 14.8 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAM43877.1 - 7.1e-07 29.6 2.4 0.14 12.5 0.1 4.3 2 2 0 2 2 2 2 AAA domain DUF87 PF01935.17 GAM43877.1 - 1.7e-05 25.0 0.3 0.033 14.3 0.1 2.8 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_30 PF13604.6 GAM43877.1 - 2e-05 24.4 0.5 0.063 13.0 0.0 3.5 3 1 0 3 3 3 2 AAA domain APS_kinase PF01583.20 GAM43877.1 - 8.1e-05 22.6 0.1 0.06 13.2 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase RsgA_GTPase PF03193.16 GAM43877.1 - 0.00021 21.3 0.0 0.088 12.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase DUF3987 PF13148.6 GAM43877.1 - 0.00028 20.0 0.0 0.036 13.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) Zeta_toxin PF06414.12 GAM43877.1 - 0.00064 19.1 0.0 0.5 9.6 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin ABC_ATPase PF09818.9 GAM43877.1 - 0.00067 18.6 0.2 0.062 12.1 0.0 2.9 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 GAM43877.1 - 0.001 18.7 1.5 1 8.9 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 GAM43877.1 - 0.0025 18.4 0.0 4.8 7.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GAM43877.1 - 0.0029 17.8 0.0 3.7 7.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 GAM43877.1 - 0.0037 17.4 0.2 5.9 7.2 0.0 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.29 GAM43877.1 - 0.0038 17.6 0.1 51 4.3 0.0 4.3 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 GAM43877.1 - 0.0055 16.5 0.5 0.11 12.3 0.0 2.9 3 1 0 3 3 2 1 DEAD/DEAH box helicase AAA_23 PF13476.6 GAM43877.1 - 0.0063 17.0 5.9 0.6 10.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 GAM43877.1 - 0.0087 16.1 0.2 5.4 7.1 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 GAM43877.1 - 0.014 15.2 5.5 0.72 9.6 0.0 4.0 3 1 1 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 GAM43877.1 - 0.019 15.0 0.0 6.2 6.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GAM43877.1 - 0.059 12.9 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 GAM43877.1 - 0.064 12.4 0.1 12 5.0 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain SRP54 PF00448.22 GAM43877.1 - 0.071 12.7 0.2 13 5.4 0.0 2.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain KdpD PF02702.17 GAM43877.1 - 0.087 12.3 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain G-alpha PF00503.20 GAM43877.1 - 0.15 11.2 0.0 11 5.0 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 GAM43877.1 - 0.15 11.8 0.0 8.1 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Cad PF03596.13 GAM43877.1 - 0.42 10.5 7.4 0.23 11.3 0.8 2.9 3 0 0 3 3 2 0 Cadmium resistance transporter Acetyltransf_8 PF13523.6 GAM43878.1 - 1.3e-41 141.6 0.1 1.8e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ECH_1 PF00378.20 GAM43879.1 - 4.4e-56 190.0 0.0 5.3e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM43879.1 - 2.5e-30 106.1 0.9 2e-26 93.3 0.2 2.4 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DoxD PF04173.13 GAM43879.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 TQO small subunit DoxD MFS_1 PF07690.16 GAM43880.1 - 3.7e-19 68.9 45.2 1.5e-17 63.6 42.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM43880.1 - 5.6e-08 31.7 20.5 1.4e-07 30.4 20.5 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2672 PF10878.8 GAM43880.1 - 0.14 12.2 0.5 0.3 11.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) adh_short PF00106.25 GAM43881.1 - 1.3e-36 125.9 0.0 1.6e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43881.1 - 2.1e-28 99.5 0.0 2.6e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 GAM43881.1 - 1.1e-08 34.9 0.0 0.00011 21.7 0.0 2.3 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) KR PF08659.10 GAM43881.1 - 7.3e-07 29.3 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAM43881.1 - 0.028 14.3 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Fungal_trans_2 PF11951.8 GAM43882.1 - 1.1e-05 24.4 0.0 5.1e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain PAF-AH_p_II PF03403.13 GAM43883.1 - 2.8e-21 75.5 0.0 1.4e-11 43.6 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 GAM43883.1 - 5.5e-08 32.0 0.0 8.9e-08 31.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 GAM43883.1 - 3.4e-05 23.2 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 GAM43883.1 - 0.00024 20.2 0.1 0.0036 16.4 0.1 2.1 1 1 0 1 1 1 1 Chlorophyllase Abhydrolase_5 PF12695.7 GAM43883.1 - 0.0052 16.6 0.4 3.6 7.3 0.0 2.4 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 GAM43883.1 - 0.013 16.1 0.3 0.038 14.6 0.1 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM43883.1 - 0.13 11.9 0.2 18 4.9 0.1 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold DNA_photolyase PF00875.18 GAM43884.1 - 3.7e-34 118.1 0.0 5.4e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase F-box-like PF12937.7 GAM43885.1 - 6e-06 26.0 0.0 1.9e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 GAM43885.1 - 0.099 12.6 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 F-box-like domain F-box PF00646.33 GAM43885.1 - 0.38 10.7 5.7 11 6.0 5.7 2.6 1 1 0 1 1 1 0 F-box domain WD40 PF00400.32 GAM43886.1 - 3.4e-19 68.8 7.9 8.8e-05 23.2 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 GAM43886.1 - 0.00016 20.4 2.2 0.13 10.8 0.2 3.4 4 0 0 4 4 4 2 Cytochrome D1 heme domain SDA1 PF05285.12 GAM43886.1 - 0.018 14.5 4.8 0.027 13.9 4.8 1.2 1 0 0 1 1 1 0 SDA1 PQQ_3 PF13570.6 GAM43886.1 - 0.024 15.1 1.3 1.7 9.2 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain DUF4604 PF15377.6 GAM43886.1 - 0.099 13.1 1.5 0.17 12.3 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DNA_pol_phi PF04931.13 GAM43886.1 - 0.51 8.4 11.3 0.67 8.0 11.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi PTPRCAP PF15713.5 GAM43886.1 - 0.67 10.2 5.2 1.3 9.3 5.2 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RRN3 PF05327.11 GAM43886.1 - 7 5.1 10.6 11 4.5 10.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SecE PF00584.20 GAM43887.1 - 1.2e-07 31.5 0.1 1.9e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_1 PF00076.22 GAM43888.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_5 PF13909.6 GAM43889.1 - 0.079 12.7 11.4 0.048 13.4 3.7 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 GAM43889.1 - 0.4 10.4 0.0 0.4 10.4 0.0 3.0 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 GAM43889.1 - 4.5 7.9 15.7 0.1 13.1 2.6 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type TPP_enzyme_C PF02775.21 GAM43890.1 - 5.1e-11 42.6 0.2 8.3e-11 41.9 0.2 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAM43890.1 - 8.7e-08 32.0 0.0 1.4e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Ifi-6-16 PF06140.13 GAM43891.1 - 8.6e-10 38.4 26.6 1.2e-09 37.9 26.1 1.6 1 1 0 1 1 1 1 Interferon-induced 6-16 family MFS_1 PF07690.16 GAM43892.1 - 2.9e-11 42.9 46.6 6.5e-05 22.0 14.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM43892.1 - 6.5e-09 34.7 16.3 8e-09 34.5 16.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPR_12 PF13424.6 GAM43893.1 - 4.4e-48 161.5 21.6 6.2e-14 52.1 0.1 7.0 5 1 2 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 GAM43893.1 - 2.8e-42 141.5 20.9 3.6e-08 33.0 0.1 9.4 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 GAM43893.1 - 3.3e-14 51.8 19.3 0.00076 19.4 0.0 8.5 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_4 PF07721.14 GAM43893.1 - 2.6e-13 49.2 0.2 0.5 11.1 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAM43893.1 - 3.3e-12 45.5 17.7 0.022 14.8 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM43893.1 - 3.3e-11 43.1 12.1 1.1e-06 28.3 3.0 3.3 2 1 1 3 3 3 3 MalT-like TPR region TPR_1 PF00515.28 GAM43893.1 - 2.2e-10 39.9 10.0 0.035 13.9 0.0 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat NB-ARC PF00931.22 GAM43893.1 - 2.9e-09 36.5 0.0 3.1e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain TPR_8 PF13181.6 GAM43893.1 - 3.4e-09 36.2 3.8 1.5 9.2 0.0 7.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM43893.1 - 7.9e-07 29.6 10.1 0.49 11.1 3.5 6.5 3 3 3 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM43893.1 - 5e-06 26.9 24.9 1.1 10.3 0.1 8.7 8 3 2 10 10 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM43893.1 - 8.8e-06 26.1 3.8 0.023 15.2 0.1 4.6 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM43893.1 - 1.7e-05 24.8 0.0 12 6.5 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM43893.1 - 0.00068 19.8 2.5 0.83 9.9 0.1 4.5 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 NACHT PF05729.12 GAM43893.1 - 0.0015 18.5 0.3 0.017 15.0 0.0 2.8 2 1 0 2 2 2 1 NACHT domain Coatomer_E PF04733.14 GAM43893.1 - 0.0054 16.2 0.9 0.45 9.9 0.1 3.2 2 1 1 3 3 3 1 Coatomer epsilon subunit AAA_33 PF13671.6 GAM43893.1 - 0.0091 16.2 0.0 0.057 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain PPR PF01535.20 GAM43893.1 - 0.015 15.5 1.7 4.6 7.7 0.0 4.8 5 0 0 5 5 4 0 PPR repeat DnaJ PF00226.31 GAM43893.1 - 0.016 15.3 0.0 0.07 13.3 0.0 2.1 1 0 0 1 1 1 0 DnaJ domain AAA_16 PF13191.6 GAM43893.1 - 0.037 14.4 0.1 0.22 11.9 0.1 2.4 1 1 0 1 1 1 0 AAA ATPase domain TPR_5 PF12688.7 GAM43893.1 - 0.43 10.8 11.7 7.3 6.9 0.1 4.2 2 1 2 4 4 4 0 Tetratrico peptide repeat MFS_1 PF07690.16 GAM43894.1 - 3e-38 131.7 28.6 3e-38 131.7 28.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM43894.1 - 1.4e-13 50.6 4.5 1.4e-13 50.6 4.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Glyco_hydro_43 PF04616.14 GAM43896.1 - 1e-37 130.0 0.0 1.3e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.24 GAM43898.1 - 7.2e-79 265.7 13.6 8.3e-79 265.5 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM43898.1 - 3.9e-19 68.8 26.1 2e-17 63.2 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_32C PF08244.12 GAM43899.1 - 2.9e-16 59.9 0.0 4.5e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 GAM43899.1 - 1e-14 54.8 0.0 3e-14 53.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain BNR PF02012.20 GAM43899.1 - 0.092 12.8 8.5 0.16 12.1 0.2 3.5 3 0 0 3 3 3 0 BNR/Asp-box repeat DUF4975 PF16346.5 GAM43899.1 - 0.14 12.2 0.1 0.23 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) Periviscerokin PF08259.11 GAM43899.1 - 0.37 11.2 0.1 0.37 11.2 0.1 2.1 2 0 0 2 2 2 0 Periviscerokinin family BNR_6 PF15899.5 GAM43899.1 - 1.2 9.4 3.3 2.6 8.3 0.7 2.5 2 0 0 2 2 2 0 BNR-Asp box repeat Methyltransf_3 PF01596.17 GAM43900.1 - 5.5e-28 97.6 0.0 6.9e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 GAM43900.1 - 2.6e-09 38.0 0.0 4.6e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 GAM43900.1 - 0.0002 21.1 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_18 PF12847.7 GAM43900.1 - 0.00024 21.0 0.0 0.0004 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAM43900.1 - 0.00033 20.5 0.2 0.00063 19.6 0.0 1.4 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 GAM43900.1 - 0.0018 17.8 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TrmK PF04816.12 GAM43900.1 - 0.0089 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_25 PF13649.6 GAM43900.1 - 0.0093 16.7 0.1 0.054 14.2 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM43900.1 - 0.07 12.9 0.0 0.6 9.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAM43900.1 - 0.15 12.7 0.1 0.61 10.8 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Glyco_hydro_79C PF16862.5 GAM43902.1 - 8.7e-12 45.8 0.0 1.8e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Mito_carr PF00153.27 GAM43904.1 - 1.2e-72 239.9 1.7 5.2e-24 84.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L21e PF01157.18 GAM43905.1 - 2.5e-45 152.4 2.2 4e-45 151.8 2.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e SMP PF04927.12 GAM43905.1 - 0.044 14.3 0.0 0.069 13.6 0.0 1.3 1 0 0 1 1 1 0 Seed maturation protein Nudix_hydro PF18290.1 GAM43905.1 - 0.16 12.0 0.2 0.3 11.1 0.2 1.4 1 0 0 1 1 1 0 Nudix hydrolase domain S4 PF01479.25 GAM43906.1 - 1.1e-12 47.4 0.8 1.1e-12 47.4 0.8 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 GAM43906.1 - 2.8e-06 28.2 0.2 5.4e-06 27.2 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Prefoldin PF02996.17 GAM43907.1 - 0.0022 17.9 2.0 0.0022 17.9 2.0 3.3 1 1 2 3 3 3 1 Prefoldin subunit Fez1 PF06818.15 GAM43907.1 - 0.0039 17.7 18.8 0.041 14.3 18.8 2.1 1 1 0 1 1 1 1 Fez1 DUF948 PF06103.11 GAM43907.1 - 0.0048 17.1 3.8 0.0097 16.1 2.2 2.1 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) ABC_tran_CTD PF16326.5 GAM43907.1 - 0.015 15.5 1.5 0.015 15.5 1.5 4.4 1 1 3 4 4 4 0 ABC transporter C-terminal domain BLOC1_2 PF10046.9 GAM43907.1 - 0.023 15.0 5.3 0.023 15.0 5.3 2.5 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 GAM43907.1 - 0.088 10.7 3.8 0.12 10.3 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Kre28 PF17097.5 GAM43907.1 - 0.19 10.6 6.6 1 8.3 6.5 2.1 1 1 0 1 1 1 0 Spindle pole body component BRE1 PF08647.11 GAM43907.1 - 0.19 11.8 16.2 0.14 12.2 2.3 3.2 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 GAM43907.1 - 0.29 10.0 20.0 0.34 9.8 8.4 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 GAM43907.1 - 0.37 11.4 18.8 1.2 9.8 2.4 3.6 2 1 1 3 3 3 0 SlyX DUF4407 PF14362.6 GAM43907.1 - 0.51 9.6 14.0 1.6 8.0 14.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) WDCP PF15390.6 GAM43907.1 - 0.59 8.5 4.2 0.65 8.3 3.2 1.4 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF1664 PF07889.12 GAM43907.1 - 0.92 9.5 6.6 0.56 10.3 3.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 GAM43907.1 - 1 9.2 13.8 1.8 8.3 4.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ADIP PF11559.8 GAM43907.1 - 1.3 9.0 17.9 2.8 8.0 1.1 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 GAM43907.1 - 1.4 9.2 15.9 0.35 11.1 5.6 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF3552 PF12072.8 GAM43907.1 - 1.4 8.3 19.6 2.1 7.7 7.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Lzipper-MIP1 PF14389.6 GAM43907.1 - 3.4 8.0 15.7 2.7 8.3 9.1 2.9 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 FAM76 PF16046.5 GAM43907.1 - 4.3 6.6 10.6 2.6 7.3 4.6 2.1 2 0 0 2 2 2 0 FAM76 protein DUF1843 PF08898.10 GAM43907.1 - 4.9 7.7 7.8 17 6.0 0.2 3.6 5 0 0 5 5 3 0 Domain of unknown function (DUF1843) HIP1_clath_bdg PF16515.5 GAM43907.1 - 5.9 7.6 16.7 4.1 8.1 7.2 2.7 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1657 PF07870.11 GAM43907.1 - 6.3 6.8 10.4 3.2 7.7 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1657) AAA_13 PF13166.6 GAM43907.1 - 6.9 5.2 11.8 19 3.7 12.0 1.4 1 1 0 1 1 1 0 AAA domain DUF2721 PF11026.8 GAM43907.1 - 7 6.6 5.5 18 5.2 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF2203 PF09969.9 GAM43907.1 - 7.1 7.4 12.3 3.7 8.3 0.9 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Prefoldin_2 PF01920.20 GAM43907.1 - 7.2 6.6 15.5 0.76 9.8 4.0 3.4 2 2 1 3 3 3 0 Prefoldin subunit UPF0449 PF15136.6 GAM43907.1 - 8.3 6.9 10.0 1.4 9.4 2.1 2.9 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 Macoilin PF09726.9 GAM43908.1 - 3.6 6.0 14.9 4.2 5.8 14.9 1.2 1 0 0 1 1 1 0 Macoilin family Vps62 PF06101.11 GAM43909.1 - 2.7e-12 45.8 2.2 6.1e-12 44.6 2.2 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Septin PF00735.18 GAM43910.1 - 1.1e-33 116.7 0.0 1.9e-11 43.8 0.0 3.2 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.18 GAM43910.1 - 0.00058 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 GAM43910.1 - 0.0069 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAM43910.1 - 0.059 13.4 1.2 0.22 11.6 0.3 2.5 2 1 0 2 2 2 0 Dynamin family G-alpha PF00503.20 GAM43910.1 - 0.069 12.3 0.0 0.18 10.9 0.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 GAM43910.1 - 0.088 13.2 0.1 0.75 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain DUF4637 PF15470.6 GAM43910.1 - 1.2 8.9 6.6 0.13 12.0 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) CAP_N PF01213.19 GAM43910.1 - 8.9 5.7 8.8 28 4.1 8.8 1.9 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Annexin PF00191.20 GAM43911.1 - 3.2e-12 46.3 3.3 0.008 16.2 0.0 4.5 4 0 0 4 4 4 4 Annexin DUF3915 PF13054.6 GAM43911.1 - 0.88 9.6 9.2 0.032 14.2 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) adh_short_C2 PF13561.6 GAM43912.1 - 6.2e-53 179.7 0.0 7.3e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM43912.1 - 1.2e-42 145.5 0.0 1.5e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM43912.1 - 3.1e-15 56.5 0.0 4.3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 GAM43912.1 - 0.0002 20.4 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM43912.1 - 0.00035 20.1 0.0 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM43912.1 - 0.0021 17.5 0.1 0.0048 16.4 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAM43912.1 - 0.017 14.2 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 GAM43912.1 - 0.017 15.3 0.0 0.045 14.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 GAM43912.1 - 0.025 14.8 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 GAM43912.1 - 0.15 11.9 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Lactamase_B PF00753.27 GAM43913.1 - 3e-11 43.7 2.0 7.8e-11 42.3 2.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM43913.1 - 1.4e-05 24.7 0.6 3.1e-05 23.6 0.6 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain WSC PF01822.19 GAM43914.1 - 3.6e-16 59.1 6.3 1e-15 57.7 6.3 1.8 1 0 0 1 1 1 1 WSC domain RelB PF04221.12 GAM43914.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 RelB antitoxin Toxin_3 PF00537.18 GAM43914.1 - 7.4 6.8 10.9 4.4 7.6 2.0 3.1 3 0 0 3 3 3 0 Scorpion toxin-like domain Aldo_ket_red PF00248.21 GAM43915.1 - 3.2e-17 62.7 0.0 7.9e-17 61.4 0.0 1.6 2 0 0 2 2 2 1 Aldo/keto reductase family His_Phos_2 PF00328.22 GAM43915.1 - 0.06 12.7 0.7 0.088 12.1 0.7 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Zn_clus PF00172.18 GAM43915.1 - 8 6.7 14.0 43 4.3 14.0 2.0 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.28 GAM43916.1 - 5.5e-36 124.2 0.0 7.9e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 AATase PF07247.12 GAM43916.1 - 1e-14 54.0 0.0 2.4e-14 52.8 0.0 1.5 1 1 0 1 1 1 1 Alcohol acetyltransferase M20_dimer PF07687.14 GAM43916.1 - 3.2e-08 33.4 0.1 7.2e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Condensation PF00668.20 GAM43916.1 - 0.00015 20.6 0.0 0.00029 19.6 0.0 1.4 1 0 0 1 1 1 1 Condensation domain WES_acyltransf PF03007.16 GAM43916.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain GPI-anchored PF10342.9 GAM43917.1 - 0.0004 21.1 0.9 0.0004 21.1 0.9 3.6 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SPX PF03105.19 GAM43917.1 - 5 6.9 6.4 5.5 6.8 6.4 1.2 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 GAM43917.1 - 8.1 5.5 23.0 9.7 5.3 23.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1993 PF09351.10 GAM43918.1 - 6.3e-56 189.0 0.3 7e-56 188.8 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) G_glu_transpept PF01019.21 GAM43920.1 - 1.9e-139 465.7 0.0 2.2e-139 465.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PALP PF00291.25 GAM43922.1 - 6e-68 229.4 3.2 6.8e-68 229.2 3.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 GAM43923.1 - 1e-13 51.4 0.4 2.4e-13 50.2 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM43923.1 - 1.9e-05 24.5 0.0 6.1e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 GAM43923.1 - 0.00077 18.8 2.0 0.0012 18.1 2.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.13 GAM43923.1 - 0.0016 18.0 1.0 0.0026 17.3 1.0 1.2 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 GAM43923.1 - 0.044 13.9 0.1 0.081 13.0 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 GAM43924.1 - 1.2e-10 42.3 0.0 2.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Fungal_trans PF04082.18 GAM43924.1 - 4e-05 22.8 1.4 6.8e-05 22.0 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFO_IDH_MocA_C PF02894.17 GAM43924.1 - 0.004 17.1 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Lactamase_B PF00753.27 GAM43925.1 - 1.2e-09 38.5 0.4 4.1e-09 36.7 0.4 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM43925.1 - 1.3e-05 24.8 0.1 2.5e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FAD_binding_3 PF01494.19 GAM43926.1 - 2e-62 211.5 0.0 2.7e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM43926.1 - 0.0021 17.7 0.1 0.0084 15.7 0.0 2.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM43926.1 - 0.014 15.6 0.0 0.044 14.0 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM43926.1 - 0.026 13.8 0.0 0.26 10.5 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM43926.1 - 0.035 13.3 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 GAM43926.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 GAM43926.1 - 0.065 11.9 0.0 0.28 9.9 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 GAM43926.1 - 0.086 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 GAM43926.1 - 0.13 12.9 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 GAM43927.1 - 0.00011 21.7 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 GAM43928.1 - 2.5e-22 79.3 0.0 7.3e-20 71.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43928.1 - 3.3e-08 33.4 0.0 1.3e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM43928.1 - 9.1e-08 32.2 0.0 1.8e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM43928.1 - 2.6e-05 23.8 0.0 3.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAM43928.1 - 0.0051 16.9 0.0 0.035 14.2 0.0 2.1 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 GAM43928.1 - 0.011 15.0 0.0 0.043 12.9 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ApoC-I PF04691.12 GAM43928.1 - 0.061 13.3 0.3 0.14 12.1 0.3 1.6 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) adh_short PF00106.25 GAM43929.1 - 1.1e-40 139.2 0.3 2.1e-40 138.3 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43929.1 - 1.2e-31 110.1 0.3 1.9e-31 109.4 0.3 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM43929.1 - 1.4e-12 47.9 0.0 2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM43929.1 - 3.5e-08 33.2 0.0 3.5e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAM43929.1 - 1e-05 25.8 0.1 0.00057 20.2 0.2 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 GAM43929.1 - 9.7e-05 22.3 0.2 0.00015 21.7 0.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAM43929.1 - 0.058 12.5 0.2 0.73 8.9 0.2 2.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein FAD_binding_3 PF01494.19 GAM43930.1 - 2.4e-21 76.4 0.1 3.8e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM43930.1 - 2.9e-07 30.4 0.1 0.0079 15.8 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM43930.1 - 3.2e-05 23.3 0.1 0.017 14.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM43930.1 - 0.00081 19.9 0.1 0.046 14.3 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 GAM43930.1 - 0.00099 18.8 0.1 0.0026 17.4 0.1 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 GAM43930.1 - 0.0029 17.8 0.0 0.0073 16.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAM43930.1 - 0.017 14.0 0.0 3.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Fungal_trans PF04082.18 GAM43931.1 - 1.4e-18 66.9 0.2 2e-18 66.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM43931.1 - 1.9e-06 27.9 13.9 3.5e-06 27.0 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 GAM43932.1 - 2.6e-22 79.2 45.2 4.4e-17 62.0 24.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM43932.1 - 0.022 13.2 26.3 0.03 12.8 26.3 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 GAM43932.1 - 0.03 14.5 0.4 0.03 14.5 0.4 2.8 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF2304 PF10066.9 GAM43932.1 - 2.7 8.3 10.7 0.24 11.6 4.6 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) MFS_1 PF07690.16 GAM43933.1 - 3.6e-27 95.2 70.0 1.9e-25 89.6 34.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipase_GDSL_2 PF13472.6 GAM43934.1 - 2.1e-16 60.8 0.0 2.5e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAM43934.1 - 6.9e-11 42.5 0.0 8.4e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Myb_DNA-binding PF00249.31 GAM43935.1 - 6.2e-07 29.5 0.2 1.2e-06 28.6 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM43935.1 - 0.015 15.5 0.1 0.036 14.3 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain SLIDE PF09111.10 GAM43935.1 - 0.1 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 SLIDE DUF3963 PF13124.6 GAM43935.1 - 0.24 11.4 0.2 0.83 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) PBP1_TM PF14812.6 GAM43935.1 - 9.7 6.6 13.8 2.8 8.4 6.3 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0016 PF01169.19 GAM43936.1 - 3.9e-39 132.8 26.3 1.1e-19 70.5 10.8 2.5 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Helo_like_N PF17111.5 GAM43936.1 - 0.11 11.9 3.3 4.1 6.7 0.0 2.5 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins DUF2070 PF09843.9 GAM43936.1 - 0.12 10.6 7.4 0.045 12.1 3.8 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) YabA PF06156.13 GAM43936.1 - 1.7 9.3 7.6 0.21 12.3 0.8 2.6 3 0 0 3 3 3 0 Initiation control protein YabA DUF3584 PF12128.8 GAM43936.1 - 2.8 5.3 8.7 1.1 6.7 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TPR_10 PF13374.6 GAM43937.1 - 1.2e-18 66.3 6.4 0.0045 16.8 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 GAM43937.1 - 8.6e-17 61.2 7.5 7.1e-08 32.6 0.1 4.1 1 1 2 4 4 4 4 Tetratricopeptide repeat NB-ARC PF00931.22 GAM43937.1 - 6.4e-05 22.3 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RE_AccI PF09545.10 GAM43937.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 AccI restriction endonuclease TPR_4 PF07721.14 GAM43937.1 - 8.4 7.4 6.8 8.2 7.4 0.9 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 GAM43938.1 - 3.3e-37 128.2 23.4 8.3e-30 103.9 5.2 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM43938.1 - 2.2e-14 53.2 2.2 2.2e-14 53.2 2.2 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAM43938.1 - 0.0053 15.2 3.9 0.0095 14.4 3.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FA_desaturase PF00487.24 GAM43938.1 - 6.4 6.5 26.1 0.13 12.0 4.4 3.7 2 2 1 4 4 4 0 Fatty acid desaturase HATPase_c PF02518.26 GAM43939.1 - 1e-22 80.7 0.1 2.5e-22 79.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM43939.1 - 3.2e-21 75.6 0.1 5.8e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAM43939.1 - 1.7e-12 47.2 0.1 7e-12 45.2 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Ago_hook PF10427.9 GAM43941.1 - 0.011 16.3 2.1 0.51 10.9 0.8 2.1 2 0 0 2 2 2 0 Argonaute hook SGT1 PF07093.11 GAM43941.1 - 0.072 11.5 0.1 0.1 11.0 0.1 1.1 1 0 0 1 1 1 0 SGT1 protein adh_short PF00106.25 GAM43942.1 - 9.5e-42 142.7 0.9 1.2e-41 142.3 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM43942.1 - 2.6e-31 109.0 0.2 3.3e-31 108.6 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 GAM43942.1 - 2.9e-06 26.9 0.0 1.7e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 GAM43942.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 GAM43942.1 - 0.027 14.5 0.0 0.045 13.7 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase NmrA PF05368.13 GAM43942.1 - 0.037 13.6 0.1 0.059 12.9 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family DUF2761 PF10959.8 GAM43942.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2761) RmlD_sub_bind PF04321.17 GAM43942.1 - 0.16 11.1 0.0 0.31 10.1 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain TPP_enzyme_N PF02776.18 GAM43943.1 - 2.6e-25 89.0 2.6 6e-25 87.8 1.7 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAM43943.1 - 1.1e-16 61.0 0.0 2.4e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAM43943.1 - 3.1e-08 33.5 0.1 7.9e-08 32.1 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain MFS_1 PF07690.16 GAM43944.1 - 8.7e-34 117.0 53.4 4.9e-29 101.4 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.22 GAM43945.1 - 5.1e-154 513.2 0.1 6e-154 513.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_18 PF00704.28 GAM43946.1 - 2.1e-63 215.0 1.4 2.3e-63 214.8 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Gln-synt_C PF00120.24 GAM43947.1 - 1.8e-58 198.2 0.0 4.2e-58 197.0 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 GAM43947.1 - 3.8e-16 59.7 0.0 8.8e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase PIN_10 PF18478.1 GAM43947.1 - 0.026 14.7 0.1 0.3 11.3 0.1 2.5 2 0 0 2 2 2 0 PIN like domain HTH_43 PF09904.9 GAM43947.1 - 0.11 12.5 0.5 0.39 10.7 0.0 2.2 2 1 1 3 3 3 0 Winged helix-turn helix GPI2 PF06432.11 GAM43948.1 - 1.6e-82 277.1 13.6 2.4e-81 273.3 9.3 2.0 2 0 0 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase Fumble PF03630.14 GAM43950.1 - 8.2e-144 478.8 0.1 1e-143 478.5 0.1 1.1 1 0 0 1 1 1 1 Fumble Glyoxal_oxid_N PF07250.11 GAM43951.1 - 5e-39 133.9 0.0 1.5e-38 132.4 0.0 1.8 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 GAM43951.1 - 1.2e-21 76.8 0.0 2.6e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) DEAD PF00270.29 GAM43952.1 - 3.6e-41 140.8 0.0 6.4e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM43952.1 - 3.6e-28 98.1 0.0 9.8e-28 96.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 GAM43952.1 - 0.00079 18.3 0.0 0.021 13.6 0.0 2.2 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ResIII PF04851.15 GAM43952.1 - 0.0019 18.2 0.0 0.0056 16.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Polysacc_deac_1 PF01522.21 GAM43953.1 - 3.6e-19 68.9 0.0 6.4e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase MoaE PF02391.17 GAM43954.1 - 1.2e-33 115.7 0.0 1.6e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 MoaE protein SCO1-SenC PF02630.14 GAM43955.1 - 2.2e-49 166.8 0.0 3.3e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 GAM43955.1 - 8.6e-05 22.4 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 GAM43955.1 - 0.015 15.6 0.0 0.034 14.5 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like APG6_N PF17675.1 GAM43956.1 - 4.1 7.9 25.6 3.5 8.2 1.2 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region Yae1_N PF09811.9 GAM43959.1 - 5.7e-12 45.1 0.2 1e-11 44.3 0.2 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal PAPS_reduct PF01507.19 GAM43959.1 - 0.071 13.1 1.6 0.18 11.8 1.3 1.7 1 1 1 2 2 2 0 Phosphoadenosine phosphosulfate reductase family DUF3176 PF11374.8 GAM43960.1 - 1.6e-24 86.2 0.0 2.7e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Zip PF02535.22 GAM43961.1 - 2.5e-34 119.0 14.9 2.5e-34 119.0 14.9 1.9 2 1 0 2 2 2 1 ZIP Zinc transporter SSP160 PF06933.11 GAM43961.1 - 0.51 8.5 8.0 0.018 13.3 0.8 1.8 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 HRXXH PF13933.6 GAM43962.1 - 3.1e-93 311.8 0.2 1.1e-92 310.1 0.2 1.7 1 1 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 GAM43962.1 - 0.0068 17.0 0.2 0.015 15.8 0.2 1.6 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Sporozoite_P67 PF05642.11 GAM43962.1 - 0.12 10.4 1.2 0.14 10.3 1.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Acatn PF13000.7 GAM43963.1 - 1.6e-164 548.5 18.9 1.4e-84 284.6 7.0 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MFS_1_like PF12832.7 GAM43963.1 - 0.037 12.9 9.1 0.076 11.9 9.1 1.4 1 0 0 1 1 1 0 MFS_1 like family IQCJ-SCHIP1 PF15157.6 GAM43964.1 - 0.72 9.7 4.5 1.2 9.0 4.5 1.3 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Goodbye PF17109.5 GAM43965.1 - 4.2e-09 36.9 0.0 4.2e-09 36.9 0.0 2.6 3 0 0 3 3 3 1 fungal STAND N-terminal Goodbye domain AAA_22 PF13401.6 GAM43965.1 - 6.5e-06 26.5 0.0 0.00011 22.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 GAM43965.1 - 0.0001 22.8 0.0 0.00067 20.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 GAM43965.1 - 0.071 12.2 0.0 0.19 10.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein EST1 PF10374.9 GAM43965.1 - 0.11 13.2 2.3 0.4 11.3 0.1 3.2 3 0 0 3 3 3 0 Telomerase activating protein Est1 AAA_25 PF13481.6 GAM43965.1 - 0.14 11.7 0.0 0.46 10.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF3328 PF11807.8 GAM43967.1 - 6.2e-52 176.5 0.0 7.7e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Phage_holin_2_4 PF16082.5 GAM43968.1 - 0.3 10.8 1.7 11 5.8 0.0 2.7 2 1 1 3 3 3 0 Bacteriophage holin family, superfamily II-like CENP-O PF09496.10 GAM43969.1 - 8.9e-68 228.4 0.2 2.5e-67 227.0 0.0 1.7 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component DivIVA PF05103.13 GAM43969.1 - 0.65 10.1 3.4 0.3 11.2 0.7 1.7 2 0 0 2 2 2 0 DivIVA protein Sugar_tr PF00083.24 GAM43971.1 - 2.1e-102 343.3 21.8 2.3e-102 343.2 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM43971.1 - 5.9e-23 81.4 32.3 3.4e-19 69.0 6.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAM43971.1 - 0.00025 19.5 2.3 0.0005 18.5 2.3 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans_2 PF11951.8 GAM43972.1 - 2.7e-19 69.3 1.4 4.1e-19 68.7 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM43973.1 - 4.3e-07 30.0 7.0 7.4e-07 29.2 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain STAG PF08514.11 GAM43973.1 - 0.016 15.1 0.3 0.038 13.9 0.3 1.5 1 0 0 1 1 1 0 STAG domain adh_short_C2 PF13561.6 GAM43974.1 - 2.5e-55 187.6 4.2 4.2e-55 186.9 4.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM43974.1 - 1.8e-39 135.3 2.0 3.4e-39 134.3 2.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM43974.1 - 1.2e-09 38.3 2.6 1.3e-09 38.2 0.4 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAM43974.1 - 0.00048 19.7 0.5 0.00084 18.9 0.3 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM43974.1 - 0.0023 17.1 0.0 0.0041 16.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAM43974.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 GAM43974.1 - 0.032 14.7 0.5 0.059 13.8 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Caudo_TAP PF02413.17 GAM43974.1 - 0.037 14.2 0.1 0.095 12.9 0.1 1.7 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK Transketolase_N PF00456.21 GAM43975.1 - 1.6e-127 425.1 0.0 2.6e-127 424.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAM43975.1 - 3.3e-37 127.9 0.0 1.2e-36 126.1 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 GAM43975.1 - 3.6e-07 29.5 0.1 6.1e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 GAM43975.1 - 1.1e-06 28.1 0.0 3.5e-06 26.4 0.0 1.8 2 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 GAM43975.1 - 0.00012 21.9 1.4 0.0054 16.5 0.6 3.5 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 GAM43975.1 - 0.01 15.7 0.1 0.026 14.4 0.1 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain L_lac_phage_MSP PF06488.11 GAM43975.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein adh_short_C2 PF13561.6 GAM43976.1 - 7.3e-50 169.7 0.0 9.8e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM43976.1 - 2.6e-42 144.5 0.0 3e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM43976.1 - 9.1e-14 51.8 0.0 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM43976.1 - 0.0095 15.4 0.0 0.24 10.8 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ABC_tran PF00005.27 GAM43977.1 - 3.5e-20 72.9 0.0 7.2e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM43977.1 - 0.00056 19.8 0.1 0.037 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM43977.1 - 0.011 15.2 0.9 0.29 10.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Aa_trans PF01490.18 GAM43977.1 - 0.075 11.7 0.9 0.099 11.3 0.9 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein AAA_29 PF13555.6 GAM43977.1 - 0.13 12.0 0.3 0.31 10.8 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAM43977.1 - 0.13 12.4 0.2 0.46 10.6 0.2 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase Atg29_N PF18388.1 GAM43978.1 - 1.2e-25 89.1 1.4 2.3e-25 88.1 1.4 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain ABC_tran PF00005.27 GAM43978.1 - 2.1e-21 76.9 0.0 4.2e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 GAM43978.1 - 0.018 14.8 0.1 0.051 13.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM43978.1 - 0.026 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 GAM43978.1 - 0.027 13.9 0.2 8.9 5.7 0.0 2.2 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAM43978.1 - 0.031 14.8 0.0 0.06 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAM43978.1 - 0.04 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 GAM43978.1 - 0.054 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 GAM43978.1 - 0.099 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 GAM43978.1 - 0.1 12.9 0.3 0.29 11.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain GST_N_2 PF13409.6 GAM43979.1 - 5.3e-11 42.7 0.0 9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAM43979.1 - 6.2e-11 42.5 0.1 1.7e-10 41.1 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM43979.1 - 1e-06 28.7 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM43979.1 - 0.01 16.1 0.0 0.033 14.5 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM43979.1 - 0.013 15.6 0.0 0.055 13.7 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_35 PF01301.19 GAM43980.1 - 1.2e-88 297.7 1.7 1.7e-88 297.3 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 CBM_1 PF00734.18 GAM43980.1 - 4.5e-14 52.1 16.3 1.1e-13 50.9 16.3 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_42 PF02449.15 GAM43980.1 - 8.9e-13 48.3 0.4 1.1e-11 44.7 0.4 2.0 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 GAM43980.1 - 8.7e-05 23.1 0.4 0.00057 20.4 0.0 2.5 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain SGP PF17228.2 GAM43980.1 - 3 8.7 11.2 0.31 11.9 4.3 2.8 3 0 0 3 3 3 0 Sulphur globule protein Sporozoite_P67 PF05642.11 GAM43980.1 - 7.6 4.5 7.7 12 3.9 7.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DFP PF04127.15 GAM43981.1 - 5.4e-10 39.4 0.0 0.012 15.4 0.0 3.8 3 1 1 4 4 4 3 DNA / pantothenate metabolism flavoprotein Fringe PF02434.16 GAM43982.1 - 0.0001 21.8 0.0 0.0022 17.5 0.0 2.3 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.26 GAM43982.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 PAN domain PAN_4 PF14295.6 GAM43982.1 - 0.016 15.1 0.5 0.033 14.1 0.5 1.5 1 0 0 1 1 1 0 PAN domain Galactosyl_T PF01762.21 GAM43982.1 - 0.043 13.6 0.0 0.87 9.4 0.0 2.3 1 1 0 1 1 1 0 Galactosyltransferase Glyco_transf_34 PF05637.12 GAM43982.1 - 0.56 9.9 2.6 0.99 9.1 2.6 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family FAD_binding_4 PF01565.23 GAM43983.1 - 4.1e-21 75.2 1.0 8.3e-21 74.2 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM43983.1 - 1.2e-09 38.1 0.4 4.3e-09 36.3 0.4 2.0 1 0 0 1 1 1 1 Berberine and berberine like Alpha-amylase PF00128.24 GAM43985.1 - 5.6e-116 387.8 0.8 5.6e-116 387.8 0.8 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 GAM43985.1 - 2.1e-08 34.1 0.0 4.5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Alpha-amylase_C PF02806.18 GAM43985.1 - 0.0048 17.3 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain hDGE_amylase PF14701.6 GAM43985.1 - 0.0081 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain MFS_1 PF07690.16 GAM43986.1 - 2.4e-34 118.8 43.3 3.8e-34 118.2 43.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_1 PF01979.20 GAM43987.1 - 2e-44 152.3 0.0 2.4e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM43987.1 - 6e-21 75.4 0.2 3.7e-15 56.3 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Fungal_trans PF04082.18 GAM43988.1 - 1.7e-17 63.3 0.2 2.9e-17 62.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM43988.1 - 0.00015 21.8 9.9 0.0003 20.9 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NMT1_3 PF16868.5 GAM43989.1 - 1.9e-12 47.2 0.0 5.5e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 NMT1-like family FAD_binding_3 PF01494.19 GAM43990.1 - 6e-51 173.7 0.0 7.2e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM43990.1 - 0.00019 21.6 0.0 0.00042 20.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM43990.1 - 0.0017 18.0 0.1 0.0036 16.9 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM43990.1 - 0.007 15.6 0.0 0.021 14.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM43990.1 - 0.0073 15.6 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 GAM43990.1 - 0.0084 14.9 0.0 0.017 13.9 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 GAM43990.1 - 0.038 13.1 0.1 0.067 12.3 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 GAM43990.1 - 0.04 13.0 0.1 0.089 11.8 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 GAM43990.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 GAM43990.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 GAM43991.1 - 4.1e-37 128.0 0.0 9.1e-37 126.9 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 NMT1 PF09084.11 GAM43991.1 - 0.0017 18.3 0.0 0.0066 16.4 0.0 1.9 2 0 0 2 2 2 1 NMT1/THI5 like DLH PF01738.18 GAM43992.1 - 3e-27 95.6 0.0 3.6e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF915 PF06028.11 GAM43992.1 - 0.0047 16.3 0.0 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 GAM43992.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Questin_oxidase PF14027.6 GAM43993.1 - 1.5e-74 251.6 0.1 1.8e-74 251.3 0.1 1.0 1 0 0 1 1 1 1 Questin oxidase-like adh_short_C2 PF13561.6 GAM43994.1 - 4.2e-57 193.4 0.3 5.3e-57 193.1 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM43994.1 - 8.5e-45 152.6 0.2 9.9e-45 152.4 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM43994.1 - 3.7e-07 30.2 0.1 9.6e-07 28.9 0.1 1.6 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 GAM43994.1 - 7.3e-06 25.3 0.1 4.9e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain Phage_Mu_Gp45 PF06890.12 GAM43994.1 - 0.031 14.0 0.0 0.17 11.7 0.0 2.1 2 1 0 2 2 2 0 Bacteriophage Mu Gp45 protein Epimerase PF01370.21 GAM43994.1 - 0.062 12.8 0.1 0.09 12.2 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 GAM43994.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) APC_r PF05923.12 GAM43995.1 - 0.00048 19.8 0.3 0.00071 19.2 0.3 1.2 1 0 0 1 1 1 1 APC repeat Fungal_trans_2 PF11951.8 GAM43996.1 - 2.5e-06 26.6 1.7 6.5e-06 25.2 0.5 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain TMEM70 PF06979.12 GAM43996.1 - 0.039 14.4 0.2 0.086 13.3 0.2 1.5 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex ADH_zinc_N PF00107.26 GAM43997.1 - 5e-12 45.9 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM43997.1 - 1.3e-08 34.7 0.0 2.9e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM43997.1 - 2e-05 25.7 0.0 4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 GAM43997.1 - 0.0032 17.3 0.0 0.0062 16.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Epimerase PF01370.21 GAM43997.1 - 0.072 12.5 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PNP_UDP_1 PF01048.20 GAM43998.1 - 2.1e-14 53.3 0.0 3.2e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily G-patch PF01585.23 GAM43999.1 - 1.6e-12 47.1 1.1 3.5e-12 46.0 1.1 1.6 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 GAM43999.1 - 3.9e-10 38.9 3.7 7.1e-10 38.0 3.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 GAM43999.1 - 6.1e-09 35.6 0.0 0.00012 21.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 GAM43999.1 - 4.6e-07 29.8 0.5 1.3e-06 28.4 0.5 1.8 1 0 0 1 1 1 1 G-patch domain RED_N PF07808.13 GAM43999.1 - 0.0062 16.1 0.8 0.0062 16.1 0.8 2.3 3 0 0 3 3 3 1 RED-like protein N-terminal region NCD3G PF07562.14 GAM43999.1 - 0.36 10.8 7.3 0.54 10.3 2.3 2.3 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Cdh1_DBD_1 PF18196.1 GAM43999.1 - 2.5 8.4 7.5 3.4 8.0 0.2 3.3 3 0 0 3 3 3 0 Chromodomain helicase DNA-binding domain 1 Arginosuc_synth PF00764.19 GAM44000.1 - 1e-47 163.3 0.0 1.4e-47 162.8 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 GAM44000.1 - 0.0031 17.0 0.0 0.0086 15.6 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 GAM44000.1 - 0.0035 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase MSA-2c PF12238.8 GAM44000.1 - 0.13 12.3 2.5 0.22 11.5 2.5 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF3445 PF11927.8 GAM44001.1 - 1.8e-63 214.2 0.0 2.1e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) MFS_1 PF07690.16 GAM44002.1 - 4.9e-36 124.4 56.7 4.9e-36 124.4 56.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM44002.1 - 3.5e-08 32.3 22.6 1.5e-07 30.2 22.6 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Endomucin PF07010.12 GAM44002.1 - 0.74 9.7 9.2 3.4 7.6 3.5 2.3 2 0 0 2 2 2 0 Endomucin IncE PF17627.2 GAM44002.1 - 1.3 9.0 8.8 3.9 7.5 0.3 3.4 3 0 0 3 3 3 0 Inclusion membrane protein E Isochorismatase PF00857.20 GAM44003.1 - 3.6e-21 76.1 0.0 5e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family AMP-binding PF00501.28 GAM44004.1 - 3.1e-301 997.9 0.1 3.7e-77 259.7 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 GAM44004.1 - 4.7e-165 549.7 0.3 1e-46 159.6 0.0 4.6 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.25 GAM44004.1 - 2.1e-51 172.1 3.8 1e-11 45.0 0.0 5.6 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAM44004.1 - 4e-08 34.1 0.1 1.5 9.8 0.0 4.7 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain Hist_deacetyl PF00850.19 GAM44005.1 - 2.1e-71 240.9 0.0 5.7e-71 239.5 0.0 1.6 1 1 0 1 1 1 1 Histone deacetylase domain TPR_10 PF13374.6 GAM44007.1 - 7.5e-62 203.7 10.3 3.4e-11 42.6 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 GAM44007.1 - 4.9e-59 196.6 17.1 2e-17 63.2 0.2 5.3 1 1 2 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAM44007.1 - 3.1e-27 93.2 11.7 7.5e-05 22.4 0.0 7.0 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 GAM44007.1 - 5.1e-23 79.4 7.3 0.0018 18.2 0.0 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat Sacchrp_dh_NADP PF03435.18 GAM44007.1 - 2.9e-19 69.6 0.6 6.6e-19 68.5 0.6 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TPR_MalT PF17874.1 GAM44007.1 - 1.5e-17 64.0 3.7 7.4e-10 38.7 0.2 3.6 1 1 2 3 3 3 3 MalT-like TPR region TPR_2 PF07719.17 GAM44007.1 - 1.1e-16 59.5 8.4 0.0047 16.9 0.0 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAM44007.1 - 8.6e-16 56.8 5.4 0.053 13.8 0.1 7.1 6 0 0 6 6 6 3 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 GAM44007.1 - 2.5e-12 46.5 0.1 8.9e-12 44.8 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_16 PF13432.6 GAM44007.1 - 1.9e-11 44.4 5.6 7.6e-05 23.3 0.3 5.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM44007.1 - 1.3e-07 31.8 7.3 0.78 10.7 0.0 7.0 6 1 1 7 7 6 1 Tetratricopeptide repeat AAA_16 PF13191.6 GAM44007.1 - 1.9e-07 31.6 0.0 5e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 GAM44007.1 - 3.6e-07 29.6 0.0 6.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_21 PF09976.9 GAM44007.1 - 6.1e-06 26.1 5.4 0.32 10.7 0.0 5.0 2 2 2 5 5 5 1 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 GAM44007.1 - 5.1e-05 23.5 0.0 9.9 7.1 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM44007.1 - 0.00019 21.1 13.3 0.11 12.3 0.0 6.0 7 0 0 7 7 7 2 TPR repeat TPR_17 PF13431.6 GAM44007.1 - 0.00023 21.3 7.2 7.1 7.3 0.0 6.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM44007.1 - 0.0038 17.7 3.6 4.3 7.9 0.2 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat RPN6_C_helix PF18503.1 GAM44007.1 - 0.034 13.9 0.3 6.4 6.6 0.1 3.0 2 0 0 2 2 2 0 26S proteasome subunit RPN6 C-terminal helix domain CoA_binding PF02629.19 GAM44007.1 - 0.042 14.5 0.2 17 6.2 0.0 2.5 2 0 0 2 2 2 0 CoA binding domain AAA_22 PF13401.6 GAM44007.1 - 0.13 12.5 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain TPR_6 PF13174.6 GAM44007.1 - 9.4 7.1 11.3 88 4.1 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Sugar_tr PF00083.24 GAM44008.1 - 1e-108 364.2 25.1 1.6e-108 363.5 25.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM44008.1 - 1.7e-24 86.4 77.4 1.1e-22 80.5 42.9 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Nop52 PF05997.12 GAM44008.1 - 0.074 12.8 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Nucleolar protein,Nop52 OATP PF03137.20 GAM44008.1 - 4.5 5.4 10.3 3.2 5.9 7.7 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 GAM44010.1 - 4.7e-18 65.2 28.4 2e-17 63.2 28.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM44010.1 - 1.8e-08 33.7 4.0 1.8e-08 33.7 4.0 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAM44010.1 - 0.00033 19.2 9.4 0.0007 18.1 9.4 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Tetraspanin PF00335.20 GAM44010.1 - 1.7 8.3 6.8 0.23 11.2 1.8 2.0 2 0 0 2 2 2 0 Tetraspanin family MFS_1 PF07690.16 GAM44011.1 - 8.5e-46 156.5 43.7 2.8e-45 154.8 43.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM44011.1 - 2.9e-19 69.0 13.9 6.8e-19 67.7 13.7 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM44011.1 - 1.5e-15 57.0 7.4 1.5e-15 57.0 7.4 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter ATG22 PF11700.8 GAM44011.1 - 0.088 11.4 15.9 0.045 12.4 11.8 2.5 2 1 0 2 2 2 0 Vacuole effluxer Atg22 like MFS_3 PF05977.13 GAM44011.1 - 0.46 8.8 15.9 0.019 13.4 5.2 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector PepX_C PF08530.10 GAM44012.1 - 1.5e-40 139.5 0.0 2.1e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 GAM44012.1 - 1.1e-38 133.4 0.4 3.6e-36 125.1 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 GAM44012.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PhyH PF05721.13 GAM44013.1 - 1.7e-08 35.0 0.0 5.7e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 GAM44013.1 - 3e-06 26.3 0.2 0.044 12.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) Methyltransf_2 PF00891.18 GAM44014.1 - 2.3e-19 69.5 0.0 3.7e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MFS_1 PF07690.16 GAM44014.1 - 2e-16 59.9 23.9 2e-16 59.9 23.9 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Dimerisation PF08100.11 GAM44014.1 - 5e-06 26.4 0.4 1.2e-05 25.2 0.4 1.7 1 0 0 1 1 1 1 Dimerisation domain Sugar_tr PF00083.24 GAM44014.1 - 7.7e-06 25.0 14.4 7.7e-06 25.0 14.4 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter Tmemb_170 PF10190.9 GAM44014.1 - 0.013 15.8 1.5 0.093 13.1 1.5 2.5 1 0 0 1 1 1 0 Putative transmembrane protein 170 Dimerisation2 PF16864.5 GAM44014.1 - 0.063 13.3 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Recombinase PF07508.13 GAM44014.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Recombinase Rrf2 PF02082.20 GAM44014.1 - 0.12 12.7 0.3 0.37 11.2 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator FAD_binding_3 PF01494.19 GAM44015.1 - 4.6e-18 65.6 2.5 3.6e-17 62.6 2.5 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM44015.1 - 3.8e-07 29.6 0.1 4.3e-06 26.2 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAM44015.1 - 1.5e-06 27.4 2.2 0.015 14.2 0.0 2.6 1 1 1 2 2 2 2 Tryptophan halogenase DAO PF01266.24 GAM44015.1 - 1.6e-06 28.0 2.3 4.8e-06 26.4 0.4 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM44015.1 - 5e-06 26.6 0.1 1.3e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM44015.1 - 6.1e-05 22.3 0.1 9.8e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 GAM44015.1 - 0.00045 19.6 0.3 0.99 8.7 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAM44015.1 - 0.0012 17.7 0.5 0.0023 16.7 0.5 1.6 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAM44015.1 - 0.0028 16.9 0.2 0.0064 15.8 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM44015.1 - 0.013 16.0 0.6 0.031 14.8 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM44015.1 - 0.025 13.6 2.0 0.4 9.7 1.7 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 GAM44015.1 - 0.028 13.7 0.1 0.069 12.4 0.1 1.6 1 0 0 1 1 1 0 Thi4 family PhyH PF05721.13 GAM44016.1 - 8.1e-08 32.8 0.1 1.4e-06 28.7 0.1 2.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 GAM44016.1 - 1.6e-06 27.2 0.0 0.092 11.5 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) Zn_clus PF00172.18 GAM44018.1 - 1.3e-08 34.8 9.2 1.3e-08 34.8 9.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3552 PF12072.8 GAM44018.1 - 0.084 12.3 0.9 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) MFS_1 PF07690.16 GAM44019.1 - 2.6e-23 82.6 53.6 2.9e-09 36.3 27.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM44019.1 - 0.00032 19.7 13.8 0.00032 19.7 13.8 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter ADH_zinc_N PF00107.26 GAM44020.1 - 7.2e-13 48.7 0.4 1.4e-12 47.7 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM44020.1 - 2.6e-07 30.5 0.0 5.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM44020.1 - 0.017 16.2 0.0 0.043 14.9 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAM44020.1 - 0.023 14.0 1.1 0.039 13.3 0.2 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 GAM44020.1 - 0.043 13.7 0.2 0.074 12.9 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 GAM44020.1 - 0.046 13.2 0.9 0.07 12.6 0.4 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Beta-prism_lec PF16458.5 GAM44020.1 - 0.082 12.9 0.2 0.36 10.8 0.0 2.1 3 0 0 3 3 3 0 Beta-prism lectin NUP PF06516.11 GAM44021.1 - 2.8e-138 460.4 0.5 3.2e-138 460.2 0.5 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Glyco_hydro_12 PF01670.16 GAM44022.1 - 6.8e-19 68.7 8.8 4.1e-17 62.9 9.1 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 12 Glyco_tranf_2_3 PF13641.6 GAM44023.1 - 7.2e-23 81.7 0.0 1.3e-22 80.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAM44023.1 - 3.5e-17 63.0 0.5 3.5e-17 63.0 0.5 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAM44023.1 - 1.7e-14 54.0 0.0 3.7e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 GAM44023.1 - 3e-14 52.5 1.8 1.1e-08 34.1 0.2 3.3 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.6 GAM44023.1 - 7e-11 41.9 0.0 1.1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 GAM44023.1 - 0.00062 18.5 0.1 0.0088 14.7 0.0 2.3 2 0 0 2 2 2 1 Chitin synthase GFA PF04828.14 GAM44024.1 - 4.5e-16 59.0 0.0 5.5e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme UPF0258 PF06789.12 GAM44025.1 - 0.0094 16.1 0.1 0.018 15.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) DUF1676 PF07898.13 GAM44025.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF3675 PF12428.8 GAM44025.1 - 3.2 8.3 4.6 21 5.7 4.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3675) DAO PF01266.24 GAM44026.1 - 1.6e-36 126.7 0.0 1.9e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM44026.1 - 0.0026 18.0 0.3 0.0069 16.6 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAM44026.1 - 0.0028 17.7 0.7 0.009 16.0 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAM44026.1 - 0.0042 16.4 0.4 0.91 8.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM44026.1 - 0.009 15.3 0.1 0.016 14.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAM44026.1 - 0.013 14.8 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM44026.1 - 0.019 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein MCRA PF06100.11 GAM44026.1 - 0.043 12.6 0.1 0.059 12.2 0.1 1.1 1 0 0 1 1 1 0 MCRA family Beta-lactamase PF00144.24 GAM44027.1 - 1.4e-49 169.2 1.2 3e-49 168.1 0.8 1.7 2 0 0 2 2 2 1 Beta-lactamase DUF3433 PF11915.8 GAM44027.1 - 8.3e-28 96.7 15.5 5.9e-24 84.3 3.2 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) DUF3471 PF11954.8 GAM44027.1 - 2.4e-10 40.8 0.0 4.7e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Abhydrolase_6 PF12697.7 GAM44029.1 - 9.5e-14 52.5 0.0 1.6e-13 51.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM44029.1 - 3.4e-07 29.8 0.0 6.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM44029.1 - 8.1e-05 22.4 0.0 0.00095 18.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 GAM44029.1 - 0.045 12.4 0.0 0.069 11.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family Slx4 PF09494.10 GAM44029.1 - 1.3 9.0 3.2 72 3.4 0.0 3.3 3 0 0 3 3 3 0 Slx4 endonuclease Beta_helix PF13229.6 GAM44030.1 - 1e-11 45.0 25.7 1.2e-10 41.5 9.0 3.7 2 1 1 3 3 3 2 Right handed beta helix region FMN_dh PF01070.18 GAM44031.1 - 3.8e-111 371.5 0.7 4.5e-111 371.2 0.7 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 GAM44031.1 - 3e-22 78.6 0.0 1.3e-21 76.5 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 GAM44031.1 - 7.8e-07 28.6 0.2 3.2e-06 26.5 0.1 1.9 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 GAM44031.1 - 7.8e-06 25.1 1.7 5.6e-05 22.3 0.6 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 GAM44031.1 - 0.00026 20.5 0.4 0.00037 20.0 0.4 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 GAM44031.1 - 0.081 12.2 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG ApbA PF02558.16 GAM44032.1 - 1.4e-33 115.7 0.1 1.8e-33 115.3 0.1 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 GAM44032.1 - 4.3e-27 94.8 0.0 6.3e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal GCD14_N PF14801.6 GAM44034.1 - 0.15 11.9 0.2 0.26 11.2 0.2 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term SMP PF04927.12 GAM44036.1 - 5.1e-15 55.7 13.2 5.1e-05 23.7 0.5 3.1 2 1 1 3 3 3 3 Seed maturation protein Ifi-6-16 PF06140.13 GAM44036.1 - 0.0035 17.2 0.3 0.0035 17.2 0.3 2.5 3 0 0 3 3 3 1 Interferon-induced 6-16 family Reo_sigma1 PF01664.16 GAM44037.1 - 0.052 12.8 0.2 3.3 6.9 0.0 2.1 2 0 0 2 2 2 0 Reovirus viral attachment protein sigma 1 DIOX_N PF14226.6 GAM44038.1 - 1.1e-18 68.1 0.0 1.5e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM44038.1 - 4.5e-17 62.4 0.0 1.7e-16 60.6 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lactamase_B_2 PF12706.7 GAM44039.1 - 3.1e-29 101.9 0.0 1.6e-28 99.6 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAM44039.1 - 9.8e-11 41.8 0.0 3e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Zn_clus PF00172.18 GAM44039.1 - 0.00014 21.9 1.3 0.00036 20.6 1.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.15 GAM44040.1 - 1.4e-182 608.6 55.8 1.7e-182 608.4 55.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Acyl_transf_1 PF00698.21 GAM44042.1 - 1.2e-16 61.1 0.2 0.00013 21.6 0.0 3.1 1 1 2 3 3 3 3 Acyl transferase domain Cys_Met_Meta_PP PF01053.20 GAM44043.1 - 1.2e-63 215.0 0.0 7.1e-63 212.4 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAM44043.1 - 0.0013 17.8 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V HAD_2 PF13419.6 GAM44044.1 - 1e-16 61.5 0.0 1.8e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM44044.1 - 1.1e-05 25.4 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAM44044.1 - 0.00034 21.0 0.0 0.00054 20.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GRDP-like PF07173.12 GAM44046.1 - 3.7e-16 60.1 15.8 8.3e-12 46.0 0.3 4.3 3 1 1 4 4 4 2 Glycine-rich domain-containing protein-like Fib_alpha PF08702.10 GAM44046.1 - 0.0017 18.5 2.8 0.0017 18.5 2.8 2.0 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 GAM44046.1 - 0.044 13.8 2.9 0.13 12.3 1.2 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) YabA PF06156.13 GAM44046.1 - 0.048 14.3 1.3 0.048 14.3 1.3 2.8 4 0 0 4 4 4 0 Initiation control protein YabA Baculo_PEP_C PF04513.12 GAM44046.1 - 0.051 13.6 0.1 0.097 12.7 0.1 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.13 GAM44046.1 - 0.22 12.3 17.8 0.087 13.6 3.8 3.4 2 1 1 3 3 3 0 Occludin homology domain T3SSipB PF16535.5 GAM44046.1 - 0.7 10.4 10.4 0.53 10.8 1.5 2.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB Nup54 PF13874.6 GAM44046.1 - 1.8 8.6 9.9 0.029 14.5 1.7 2.1 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Atg14 PF10186.9 GAM44046.1 - 5.6 5.9 18.7 22 4.0 18.7 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_23 PF13476.6 GAM44046.1 - 8.4 6.8 10.2 15 6.0 10.2 1.4 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 GAM44047.1 - 2.1e-96 323.5 0.0 2.6e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_114 PF03537.13 GAM44048.1 - 3.3e-89 298.2 4.4 5.5e-89 297.5 4.4 1.3 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 DRMBL PF07522.14 GAM44048.1 - 1.9e-34 118.2 0.0 5.1e-34 116.8 0.0 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 GAM44048.1 - 5.5e-06 26.0 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAM44048.1 - 0.029 14.4 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Methyltransf_11 PF08241.12 GAM44049.1 - 4.4e-07 30.5 0.0 1.1e-06 29.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM44049.1 - 0.016 15.9 0.0 0.045 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 GAM44050.1 - 7.5e-10 38.9 0.0 1.6e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM44050.1 - 0.003 17.4 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain F-box-like PF12937.7 GAM44050.1 - 0.0063 16.4 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM44050.1 - 0.051 13.5 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 F-box domain PGM_PMM_I PF02878.16 GAM44051.1 - 7.2e-15 54.9 0.0 1.7e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 GAM44051.1 - 4.8e-08 33.2 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 GAM44051.1 - 2.3e-07 31.3 0.0 4.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 GAM44051.1 - 1.6e-05 25.0 0.1 0.00016 21.7 0.0 2.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ank_2 PF12796.7 GAM44052.1 - 5.7e-34 116.6 1.0 4.1e-18 65.7 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM44052.1 - 4.2e-27 94.2 0.2 7.1e-11 42.4 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM44052.1 - 1.5e-21 74.2 0.0 3.2e-05 24.0 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 GAM44052.1 - 2e-20 72.3 1.4 6.6e-06 26.3 0.1 5.4 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAM44052.1 - 2.6e-19 69.0 3.4 5.6e-06 26.5 0.2 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DUF4205 PF13898.6 GAM44052.1 - 0.056 12.4 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) MFS_1 PF07690.16 GAM44054.1 - 8.9e-24 84.1 43.7 8.9e-24 84.1 43.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM44054.1 - 2.9e-16 59.0 25.3 4.1e-16 58.5 25.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ArAE_2_N PF10337.9 GAM44054.1 - 0.21 10.6 7.8 0.018 14.1 3.0 1.6 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal RNase_H PF00075.24 GAM44055.1 - 5.3e-12 46.1 0.0 7.2e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 GAM44055.1 - 0.0023 17.7 0.3 0.14 11.9 0.3 2.2 1 1 0 1 1 1 1 Reverse transcriptase-like MFS_1 PF07690.16 GAM44056.1 - 2.7e-11 43.0 55.2 6.8e-08 31.8 17.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TPT PF03151.16 GAM44057.1 - 2.8e-20 72.8 16.0 3.6e-20 72.5 16.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAM44057.1 - 2.3e-06 27.8 31.0 0.00062 19.9 11.0 2.7 2 1 0 2 2 2 2 EamA-like transporter family NADHdh-2_N PF12155.8 GAM44057.1 - 5 7.6 12.9 0.16 12.3 0.5 3.5 2 1 1 3 3 3 0 NADH dehydrogenase subunit 2 N-terminal zf-C2H2_4 PF13894.6 GAM44058.1 - 3.6e-05 24.2 21.6 0.00075 20.1 2.4 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM44058.1 - 7.5e-05 23.0 19.8 0.15 12.6 2.5 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type Homeobox_KN PF05920.11 GAM44058.1 - 0.00014 21.7 1.2 0.00036 20.4 1.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 GAM44058.1 - 0.0019 18.2 0.0 0.0056 16.7 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 GAM44058.1 - 0.002 17.9 0.8 0.0058 16.4 0.8 1.8 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 GAM44058.1 - 0.085 12.3 0.1 0.25 10.9 0.1 1.8 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez zf-C2H2_2 PF12756.7 GAM44058.1 - 0.6 10.5 4.4 18 5.7 0.0 3.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 GAM44058.1 - 4 8.0 10.8 0.38 11.3 0.7 3.2 3 1 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.15 GAM44059.1 - 0.019 15.0 3.5 0.74 9.9 0.1 2.6 2 0 0 2 2 2 0 BED zinc finger SH3BGR PF04908.15 GAM44060.1 - 5.4e-05 23.3 0.0 0.00028 21.0 0.0 2.3 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Ribul_P_3_epim PF00834.19 GAM44061.1 - 1.2e-61 207.5 0.0 1.8e-60 203.8 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 GAM44061.1 - 0.049 12.9 0.1 0.072 12.4 0.1 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 GAM44061.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TPR_10 PF13374.6 GAM44062.1 - 4.8e-61 201.1 1.1 1e-11 44.3 0.0 7.0 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 GAM44062.1 - 3.8e-44 148.9 6.4 1.5e-14 54.1 0.1 4.9 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAM44062.1 - 5.6e-17 60.4 5.2 0.19 11.8 0.1 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 GAM44062.1 - 4e-10 39.3 0.0 7.1e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.22 GAM44062.1 - 1.1e-09 37.8 0.1 4.7e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain TPR_1 PF00515.28 GAM44062.1 - 1.9e-09 36.9 8.2 1.4 8.9 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAM44062.1 - 8.2e-09 34.9 8.2 1.7 8.9 0.1 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAM44062.1 - 3e-07 30.9 4.5 0.43 11.1 0.1 6.4 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM44062.1 - 8.3e-07 28.7 6.8 3.8e-06 26.5 1.6 2.7 1 1 2 3 3 3 2 MalT-like TPR region AAA_16 PF13191.6 GAM44062.1 - 2.6e-06 27.9 0.0 9.6e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain TPR_17 PF13431.6 GAM44062.1 - 5.1e-06 26.5 6.9 9.7 6.8 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_22 PF13401.6 GAM44062.1 - 0.0044 17.3 0.0 0.043 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAM44062.1 - 0.0052 16.7 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_16 PF13432.6 GAM44062.1 - 0.013 16.2 1.0 20 5.9 0.1 4.4 4 1 0 4 4 3 0 Tetratricopeptide repeat ATPase_2 PF01637.18 GAM44062.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF1897 PF09005.10 GAM44062.1 - 0.025 14.1 1.7 34 4.0 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) AAA_5 PF07728.14 GAM44062.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ANAPC3 PF12895.7 GAM44062.1 - 0.099 12.9 0.2 5.1 7.4 0.0 3.6 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA_18 PF13238.6 GAM44062.1 - 0.12 12.9 0.0 0.37 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 GAM44062.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 GAM44062.1 - 0.16 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TPR_8 PF13181.6 GAM44062.1 - 1.6 9.1 6.9 13 6.4 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat CNOT1_TTP_bind PF16417.5 GAM44063.1 - 0.062 12.5 0.5 0.1 11.7 0.5 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain ACI44 PF15270.6 GAM44064.1 - 1.7 8.9 8.6 2 8.7 1.1 2.2 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor Colipase PF01114.18 GAM44064.1 - 3.1 7.5 16.6 6.4 6.5 4.3 2.3 2 0 0 2 2 2 0 Colipase, N-terminal domain adh_short PF00106.25 GAM44067.1 - 5.4e-14 52.1 0.1 1.2e-10 41.2 0.1 3.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM44067.1 - 3.1e-08 33.4 0.0 2.3e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM44067.1 - 5.5e-05 23.2 0.0 9.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Cas_Cas4 PF01930.17 GAM44067.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF83 Peripla_BP_1 PF00532.21 GAM44067.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Oxidored_nitro PF00148.19 GAM44067.1 - 0.099 11.3 0.0 2 7.1 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase PBP PF01161.20 GAM44068.1 - 3.7e-17 62.9 0.9 4.7e-17 62.6 0.9 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Zn_clus PF00172.18 GAM44069.1 - 4.9e-05 23.4 12.2 0.00015 21.8 12.2 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAM44069.1 - 0.0085 14.9 0.0 0.0085 14.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 GAM44070.1 - 1.9e-09 36.9 3.8 4.3e-09 35.7 3.8 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF982 PF06169.12 GAM44070.1 - 0.14 12.2 0.1 0.58 10.2 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF982) FAD_binding_3 PF01494.19 GAM44071.1 - 6.2e-24 84.9 0.0 3.4e-23 82.5 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM44071.1 - 4e-07 30.0 0.1 0.00027 20.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM44071.1 - 6.6e-05 22.2 0.1 0.00012 21.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM44071.1 - 9.5e-05 22.6 0.2 0.00026 21.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAM44071.1 - 0.00026 20.2 0.1 0.047 12.7 0.1 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAM44071.1 - 0.0014 18.0 0.1 0.062 12.5 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 GAM44071.1 - 0.0025 16.9 0.0 0.13 11.3 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase Thi4 PF01946.17 GAM44071.1 - 0.0038 16.5 0.1 0.0058 15.9 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 GAM44071.1 - 0.0081 15.5 0.2 0.016 14.4 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM44071.1 - 0.014 15.9 0.1 0.54 10.9 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 GAM44071.1 - 0.023 15.2 0.1 0.067 13.8 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 GAM44071.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 GAM44071.1 - 0.069 13.1 0.3 0.42 10.6 0.2 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding IlvN PF07991.12 GAM44071.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain K_oxygenase PF13434.6 GAM44071.1 - 0.15 11.2 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 GAM44071.1 - 0.21 10.2 0.1 1.1 7.9 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Aldo_ket_red PF00248.21 GAM44072.1 - 2.2e-75 253.6 0.0 2.5e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pyridox_ox_2 PF12900.7 GAM44073.1 - 6.1e-22 78.1 0.0 1.4e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_S9 PF00326.21 GAM44073.1 - 0.027 14.0 0.0 0.065 12.7 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Amidase PF01425.21 GAM44074.1 - 2.5e-108 362.9 0.0 3.7e-108 362.4 0.0 1.2 1 0 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.8 GAM44075.1 - 1.1e-40 139.7 1.3 1.3e-40 139.5 1.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fig1 PF12351.8 GAM44075.1 - 0.021 14.8 0.5 0.19 11.6 0.2 2.1 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 SNO PF01174.19 GAM44075.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Retrotrans_gag PF03732.17 GAM44076.1 - 0.013 15.8 0.1 0.027 14.7 0.0 1.6 2 0 0 2 2 2 0 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 GAM44076.1 - 0.038 13.7 0.4 0.13 12.0 0.4 1.7 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type YpmT PF17431.2 GAM44076.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized YmpT-like adh_short PF00106.25 GAM44078.1 - 0.0089 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase GPI2 PF06432.11 GAM44079.1 - 0.033 13.6 8.9 0.4 10.1 3.1 2.4 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase PMT_4TMC PF16192.5 GAM44079.1 - 0.12 11.9 10.3 0.78 9.3 9.3 2.2 1 1 1 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase SCIMP PF15050.6 GAM44079.1 - 0.43 11.0 6.0 1.2 9.6 3.6 2.4 1 1 1 2 2 2 0 SCIMP protein Cation_ATPase_C PF00689.21 GAM44079.1 - 3.6 7.3 9.0 6.5 6.4 9.0 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Virul_fac_BrkB PF03631.15 GAM44079.1 - 6.1 6.4 12.5 82 2.7 12.4 2.1 1 1 0 1 1 1 0 Virulence factor BrkB MFS_1 PF07690.16 GAM44080.1 - 4e-19 68.8 38.4 5.7e-19 68.2 38.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fibrinogen_aC PF12160.8 GAM44080.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha C domain DUF4131 PF13567.6 GAM44080.1 - 0.41 10.3 5.5 0.91 9.1 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) FAD_binding_3 PF01494.19 GAM44082.1 - 1.7e-17 63.7 0.0 2.7e-16 59.7 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM44082.1 - 3.9e-06 27.0 0.1 8.7e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM44082.1 - 0.0002 21.1 0.1 0.0019 17.9 0.1 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM44082.1 - 0.0022 17.3 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM44082.1 - 0.0059 17.1 0.0 0.094 13.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM44082.1 - 0.012 14.9 0.1 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 GAM44082.1 - 0.07 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain MFS_1 PF07690.16 GAM44084.1 - 6.3e-35 120.7 31.4 1.7e-33 116.0 30.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.9 GAM44084.1 - 0.03 14.5 0.2 1.8 8.8 0.0 3.1 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Holin_BhlA PF10960.8 GAM44084.1 - 0.16 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 BhlA holin family Glyco_hydro_18 PF00704.28 GAM44085.1 - 9.9e-23 81.3 3.1 2.6e-22 79.9 3.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.18 GAM44085.1 - 1.1e-09 38.0 9.7 1.1e-09 38.0 9.7 3.1 3 0 0 3 3 3 1 Fungal cellulose binding domain Abhydrolase_3 PF07859.13 GAM44086.1 - 7.2e-27 94.6 0.0 2.2e-25 89.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAM44086.1 - 0.048 12.5 0.2 5.3 5.8 0.2 2.1 1 1 1 2 2 2 0 Carboxylesterase family tRNA-synt_1d PF00750.19 GAM44087.1 - 1.8e-65 221.2 0.0 2.6e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 GAM44087.1 - 1.2e-13 51.3 0.0 2.6e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain NRIP1_repr_3 PF15689.5 GAM44087.1 - 0.0036 17.6 0.3 0.014 15.7 0.3 2.0 1 0 0 1 1 1 1 Nuclear receptor-interacting protein 1 repression 3 CCDC53 PF10152.9 GAM44087.1 - 2.9 8.3 0.0 2.9 8.3 0.0 3.5 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex BTB PF00651.31 GAM44089.1 - 3e-10 40.3 0.1 8.2e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Ist1 PF03398.14 GAM44089.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway TFIIF_alpha PF05793.12 GAM44089.1 - 0.19 10.3 6.2 0.28 9.7 6.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) tRNA-synt_1c PF00749.21 GAM44090.1 - 1.7e-56 191.4 1.0 3.4e-43 147.7 0.1 2.4 2 1 1 3 3 3 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAM44090.1 - 1.8e-25 89.8 0.0 4.5e-25 88.5 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF3328 PF11807.8 GAM44091.1 - 1.5e-55 188.4 0.1 1.8e-55 188.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) CD225 PF04505.12 GAM44092.1 - 0.014 15.6 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF3328 PF11807.8 GAM44093.1 - 0.01 15.6 0.2 0.031 14.0 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) p450 PF00067.22 GAM44094.1 - 3e-46 158.1 0.0 9.3e-46 156.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Amidohydro_1 PF01979.20 GAM44095.1 - 2.3e-49 168.6 0.1 3e-49 168.2 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM44095.1 - 4.6e-18 65.9 0.9 5.5e-13 49.2 0.1 2.8 2 1 1 3 3 3 2 Amidohydrolase family A_deaminase PF00962.22 GAM44095.1 - 0.0085 15.5 0.1 0.034 13.5 0.0 1.8 2 0 0 2 2 2 1 Adenosine/AMP deaminase Xan_ur_permease PF00860.20 GAM44096.1 - 3.4e-50 170.9 31.8 1.5e-49 168.8 31.8 1.8 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 GAM44096.1 - 0.00042 20.7 4.0 0.00042 20.7 4.0 3.8 4 0 0 4 4 4 1 Molybdate transporter of MFS superfamily Zn_clus PF00172.18 GAM44097.1 - 1.6e-07 31.4 10.9 3.4e-07 30.3 10.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAM44097.1 - 0.0044 16.1 1.8 0.0092 15.0 1.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DIOX_N PF14226.6 GAM44098.1 - 1.1e-17 64.8 0.0 1.7e-16 61.0 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM44098.1 - 4.4e-16 59.2 0.0 7.7e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AP_endonuc_2 PF01261.24 GAM44100.1 - 1.6e-29 102.9 0.0 6.8e-29 100.8 0.0 1.8 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel adh_short_C2 PF13561.6 GAM44101.1 - 4.2e-58 196.7 0.0 4.8e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM44101.1 - 1.9e-44 151.5 0.0 2.2e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM44101.1 - 1.9e-11 44.2 0.0 3.6e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM44101.1 - 4.9e-06 26.2 0.0 0.00037 20.0 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM44101.1 - 0.00011 21.5 0.0 0.00015 21.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAM44101.1 - 0.00061 19.3 0.0 0.00086 18.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 GAM44101.1 - 0.047 14.1 0.0 0.073 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 GAM44101.1 - 0.1 12.9 0.0 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 GAM44101.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAM44101.1 - 0.21 10.6 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sugar_tr PF00083.24 GAM44102.1 - 1.1e-120 403.6 30.1 1.2e-120 403.4 30.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM44102.1 - 1.9e-26 92.8 69.0 6.2e-23 81.3 36.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 GAM44102.1 - 0.00041 19.4 8.6 0.00074 18.5 2.9 2.5 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM Sugar_tr PF00083.24 GAM44103.1 - 1.1e-111 374.0 18.5 1.2e-111 373.8 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM44103.1 - 1.2e-20 73.8 35.6 1.9e-16 60.0 5.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 GAM44104.1 - 5.1e-18 65.0 0.1 8.4e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S15 PF02129.18 GAM44106.1 - 6e-47 160.5 1.2 8.8e-47 159.9 1.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) MFS_1 PF07690.16 GAM44106.1 - 7.9e-38 130.3 43.6 1.4e-37 129.5 43.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily PepX_C PF08530.10 GAM44106.1 - 3.9e-37 128.4 0.2 6e-37 127.8 0.2 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Sugar_tr PF00083.24 GAM44106.1 - 2.6e-11 43.1 11.5 3.2e-11 42.7 10.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter ADH_N PF08240.12 GAM44106.1 - 2.4e-07 30.6 0.0 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM44106.1 - 2.2e-05 24.4 0.1 4.7e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 GAM44106.1 - 0.065 12.7 0.5 0.099 12.1 0.5 1.2 1 0 0 1 1 1 0 short chain dehydrogenase TMPIT PF07851.13 GAM44106.1 - 0.41 9.9 0.7 0.81 8.9 0.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein OATP PF03137.20 GAM44106.1 - 0.79 7.9 8.0 0.17 10.1 1.6 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cupin_2 PF07883.11 GAM44107.1 - 8.8e-09 35.0 0.0 1.3e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 GAM44107.1 - 0.077 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain ABC_tran PF00005.27 GAM44108.1 - 7.2e-43 146.4 0.2 2.2e-25 89.8 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 GAM44108.1 - 1.3e-27 97.2 25.7 1.9e-27 96.6 9.8 2.8 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 GAM44108.1 - 1e-15 57.8 2.7 2.7e-07 30.3 0.0 4.0 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAM44108.1 - 1.3e-09 38.3 1.9 0.13 12.0 0.0 5.2 4 1 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM44108.1 - 7.6e-08 32.0 2.8 0.0051 16.5 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAM44108.1 - 1.1e-06 29.3 0.2 0.044 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAM44108.1 - 7.8e-06 26.4 0.0 0.23 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 GAM44108.1 - 9.4e-05 22.5 0.8 0.21 11.6 0.1 2.6 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 GAM44108.1 - 0.00011 22.3 2.6 0.4 10.8 0.2 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM44108.1 - 0.00076 19.4 0.9 0.82 9.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 GAM44108.1 - 0.0011 18.8 0.6 0.16 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAM44108.1 - 0.0026 18.0 1.6 0.48 10.7 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM44108.1 - 0.0038 17.8 0.1 0.45 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAM44108.1 - 0.0042 16.2 1.5 0.71 8.9 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 GAM44108.1 - 0.0046 16.3 0.6 0.71 9.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP-synt_ab PF00006.25 GAM44108.1 - 0.0048 16.6 0.2 3 7.5 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 GAM44108.1 - 0.0069 15.7 0.1 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin MeaB PF03308.16 GAM44108.1 - 0.049 12.6 0.3 0.3 10.0 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB LPD3 PF18798.1 GAM44108.1 - 0.051 13.8 0.2 0.74 10.1 0.0 2.7 3 0 0 3 3 2 0 Large polyvalent protein-associated domain 3 RNA_helicase PF00910.22 GAM44108.1 - 0.052 13.9 0.3 6.1 7.3 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.6 GAM44108.1 - 0.058 13.1 0.8 4.9 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 GAM44108.1 - 0.1 12.4 1.8 0.56 10.0 0.2 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 GAM44108.1 - 0.15 12.3 1.1 37 4.5 0.1 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase PRK PF00485.18 GAM44108.1 - 0.47 10.2 1.3 0.63 9.8 0.2 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 GAM44108.1 - 0.47 10.5 4.2 1.1 9.3 0.1 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain ABC_ATPase PF09818.9 GAM44108.1 - 0.54 9.0 2.6 0.34 9.7 0.4 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Tim17 PF02466.19 GAM44109.1 - 8.6e-31 106.6 7.4 1.1e-30 106.3 7.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.6 GAM44109.1 - 0.074 13.2 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal DUF1582 PF07621.11 GAM44110.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) AMP-binding PF00501.28 GAM44111.1 - 4.8e-142 473.5 0.0 8.7e-74 248.6 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 GAM44111.1 - 2.7e-68 230.7 0.0 9e-41 140.0 0.0 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 GAM44111.1 - 4.3e-33 113.5 1.3 8.6e-10 38.8 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAM44111.1 - 3e-06 28.1 0.0 0.029 15.3 0.0 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Ribosomal_S7 PF00177.21 GAM44111.1 - 0.051 13.2 0.2 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e AMP-binding PF00501.28 GAM44113.1 - 9.9e-77 258.3 0.0 1.3e-76 257.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 GAM44113.1 - 7.2e-65 219.4 0.1 1.9e-36 125.7 0.0 3.3 2 1 1 3 3 3 3 Condensation domain PP-binding PF00550.25 GAM44113.1 - 3.7e-20 72.0 0.3 1.2e-11 44.8 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 GAM44114.1 - 3.1e-17 63.5 0.0 4.4e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 GAM44114.1 - 0.00013 22.6 0.0 0.00017 22.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM44114.1 - 0.00074 18.8 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 GAM44114.1 - 0.0036 17.2 0.0 0.0045 16.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 GAM44114.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 GAM44114.1 - 0.15 11.9 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AMP-binding PF00501.28 GAM44115.1 - 8.8e-64 215.6 0.0 1.2e-63 215.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM44115.1 - 4.3e-17 62.8 0.7 1.2e-16 61.4 0.6 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 GAM44116.1 - 2.9e-70 236.7 0.0 5.6e-70 235.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAM44116.1 - 2.9e-62 209.8 0.2 7.9e-62 208.4 0.2 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 GAM44116.1 - 7.7e-54 182.9 0.0 1.2e-53 182.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAM44116.1 - 1.5e-46 159.4 0.0 2.8e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM44116.1 - 4.4e-39 133.1 0.1 1.2e-38 131.7 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 GAM44116.1 - 3.5e-21 75.8 0.0 1.3e-20 73.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 GAM44116.1 - 4.7e-19 68.6 0.2 1.6e-17 63.7 0.1 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM44116.1 - 7.4e-18 65.9 0.0 4.8e-16 60.0 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 GAM44116.1 - 4.7e-17 62.1 0.1 1.3e-16 60.6 0.1 1.8 1 0 0 1 1 1 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 GAM44116.1 - 8.8e-14 51.9 0.0 2.4e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 GAM44116.1 - 2.5e-12 47.4 0.0 2.8e-11 44.0 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain adh_short_C2 PF13561.6 GAM44116.1 - 1.1e-11 44.7 0.1 3.2e-11 43.3 0.0 1.7 2 0 0 2 2 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_11 PF08241.12 GAM44116.1 - 8.5e-10 39.2 0.1 1.9e-08 34.8 0.0 3.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM44116.1 - 8.1e-09 35.5 0.0 1.7e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 GAM44116.1 - 1.5e-07 31.7 0.0 4.2e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 GAM44116.1 - 2.7e-07 30.2 0.0 1.7e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAM44116.1 - 6.1e-06 26.1 0.0 1.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAM44116.1 - 9e-05 22.3 0.0 0.00053 19.8 0.0 2.1 2 0 0 2 2 2 1 Lysine methyltransferase 3Beta_HSD PF01073.19 GAM44116.1 - 0.0025 16.9 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family SAT PF16073.5 GAM44116.1 - 0.008 15.9 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_N PF00108.23 GAM44116.1 - 0.051 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 GAM44116.1 - 0.092 11.9 0.0 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DREV PF05219.12 GAM44116.1 - 0.2 10.7 0.0 0.42 9.7 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase p450 PF00067.22 GAM44117.1 - 6.2e-36 124.1 0.1 7.5e-36 123.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 AATase PF07247.12 GAM44118.1 - 1.4e-19 70.1 0.0 6.8e-19 67.8 0.0 2.0 1 1 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 GAM44118.1 - 0.0073 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 GAM44118.1 - 0.04 12.6 0.0 0.12 11.0 0.0 1.8 2 0 0 2 2 2 0 Condensation domain PIG-L PF02585.17 GAM44119.1 - 2.6e-22 79.9 0.0 3.5e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Gly_transf_sug PF04488.15 GAM44120.1 - 2.5e-10 40.8 0.0 7.1e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif NB PF04159.13 GAM44120.1 - 0.16 12.1 0.0 2.8 8.0 0.0 2.2 2 0 0 2 2 2 0 NB glycoprotein Methyltransf_25 PF13649.6 GAM44121.1 - 3.5e-12 46.9 0.0 6.9e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM44121.1 - 6.4e-12 46.0 0.0 1.5e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM44121.1 - 2.4e-08 33.9 0.0 4.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM44121.1 - 1.3e-06 28.4 0.0 3.5e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM44121.1 - 4.4e-06 27.3 0.0 8.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM44121.1 - 3.4e-05 23.3 0.0 6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAM44121.1 - 0.0076 15.8 0.0 0.013 15.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Hemopexin PF00045.19 GAM44121.1 - 0.073 13.0 0.2 0.31 11.0 0.1 2.1 2 0 0 2 2 2 0 Hemopexin Methyltransf_32 PF13679.6 GAM44121.1 - 0.081 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 GAM44121.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 GAM44121.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Metallophos PF00149.28 GAM44122.1 - 1.4e-08 35.5 0.2 1.8e-08 35.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM44122.1 - 0.021 15.0 0.0 0.052 13.7 0.0 1.8 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Elicitin PF00964.17 GAM44122.1 - 0.19 11.8 3.9 5.2 7.2 0.2 2.5 2 0 0 2 2 2 0 Elicitin Ribonuclease PF00545.20 GAM44123.1 - 2.7e-09 37.7 0.1 4.1e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 ribonuclease FMN_dh PF01070.18 GAM44124.1 - 1.9e-99 333.0 0.0 2.3e-99 332.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 GAM44124.1 - 8.5e-23 80.3 0.4 3e-22 78.5 0.0 2.1 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 GAM44124.1 - 3.4e-05 23.0 1.1 0.00011 21.3 0.5 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 GAM44124.1 - 6e-05 22.4 0.0 0.0001 21.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 GAM44124.1 - 0.03 13.7 0.1 0.046 13.1 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.21 GAM44124.1 - 0.15 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase COesterase PF00135.28 GAM44125.1 - 1.5e-10 40.6 0.9 5.4e-10 38.7 0.9 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM44125.1 - 9.2e-10 38.7 0.0 1.2e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 GAM44125.1 - 0.001 18.1 0.0 0.0014 17.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.7 GAM44125.1 - 0.0013 19.4 0.4 0.0023 18.6 0.1 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 GAM44125.1 - 0.0029 16.6 0.0 0.0038 16.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Say1_Mug180 PF10340.9 GAM44125.1 - 0.0069 15.3 0.1 0.012 14.5 0.1 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase MFS_1 PF07690.16 GAM44126.1 - 1.7e-28 99.6 36.7 1.7e-28 99.6 36.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAM44126.1 - 7.2e-05 22.2 7.6 7.2e-05 22.2 7.6 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB FA_desaturase PF00487.24 GAM44127.1 - 0.0004 20.3 1.0 0.00059 19.8 1.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF2070 PF09843.9 GAM44127.1 - 0.52 8.5 4.8 0.7 8.1 4.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) adh_short_C2 PF13561.6 GAM44128.1 - 8.2e-35 120.5 0.7 1.4e-33 116.4 0.7 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM44128.1 - 7.7e-21 74.4 0.6 4.6e-20 71.9 0.6 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM44128.1 - 0.00027 20.9 0.7 0.026 14.4 0.0 2.2 1 1 1 2 2 2 2 KR domain DUF1485 PF07364.12 GAM44128.1 - 0.054 12.8 0.1 0.25 10.6 0.0 1.8 2 0 0 2 2 2 0 Metallopeptidase family M81 ADH_zinc_N PF00107.26 GAM44129.1 - 1.1e-08 35.1 0.0 2.9e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM44129.1 - 2e-05 24.4 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAM44129.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Glyco_hydro_38N PF01074.22 GAM44130.1 - 8.4e-83 278.1 0.2 1.3e-82 277.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAM44130.1 - 3.4e-54 184.2 0.0 5.3e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GAM44130.1 - 9.6e-10 38.5 0.2 3.1e-07 30.4 0.0 2.7 1 1 1 2 2 2 2 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 GAM44130.1 - 7.9e-09 35.5 0.0 8.6e-08 32.2 0.0 2.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain MFS_1 PF07690.16 GAM44131.1 - 1.9e-30 106.0 28.4 2.5e-30 105.6 28.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.25 GAM44131.1 - 1.5e-20 73.5 0.1 3.2e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM44131.1 - 5.3e-20 72.0 0.1 3e-19 69.5 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase GFO_IDH_MocA PF01408.22 GAM44131.1 - 1.9e-08 35.1 0.0 4.8e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAM44131.1 - 0.00065 19.7 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF1776 PF08643.10 GAM44131.1 - 0.041 13.3 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MWFE PF15879.5 GAM44131.1 - 0.84 9.8 4.1 21 5.4 0.1 4.3 5 0 0 5 5 5 0 NADH-ubiquinone oxidoreductase MWFE subunit Hepar_II_III PF07940.13 GAM44132.1 - 4.2e-10 39.6 0.1 9e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 Heparinase II/III-like protein DUF4962 PF16332.5 GAM44132.1 - 4.2e-06 25.5 0.5 6.2e-06 25.0 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4962) MFS_1 PF07690.16 GAM44133.1 - 7.6e-13 48.1 31.5 2e-12 46.7 31.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAM44133.1 - 3.8e-12 46.2 6.1 3.8e-12 46.2 6.1 2.3 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Arif-1 PF06770.11 GAM44133.1 - 0.0042 16.8 0.9 0.18 11.5 0.0 2.7 2 0 0 2 2 2 1 Actin-rearrangement-inducing factor (Arif-1) PucR PF07905.11 GAM44133.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family MANEC PF07502.14 GAM44134.1 - 9.8e-07 29.0 3.6 0.012 15.9 0.1 2.6 2 0 0 2 2 2 2 MANEC domain PAN_4 PF14295.6 GAM44134.1 - 0.00053 19.8 19.4 0.0009 19.1 0.6 3.6 4 1 0 4 4 4 2 PAN domain Fungal_trans_2 PF11951.8 GAM44135.1 - 3.1e-64 217.2 1.7 3.9e-64 216.8 1.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM44135.1 - 2.8e-08 33.7 12.1 7.2e-08 32.4 12.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.24 GAM44136.1 - 5.6e-24 85.4 0.0 8.2e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase OPT PF03169.15 GAM44137.1 - 1.6e-168 562.2 51.1 1.8e-168 562.0 51.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Fungal_trans PF04082.18 GAM44138.1 - 8.5e-12 44.7 0.1 1.3e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAM44138.1 - 1.6e-09 37.7 9.2 3e-09 36.9 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.6 GAM44139.1 - 3.6e-20 73.4 0.1 8.8e-20 72.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAM44139.1 - 7.2e-15 55.1 0.7 1.3e-14 54.3 0.4 1.5 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM44139.1 - 0.00075 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sugar_tr PF00083.24 GAM44140.1 - 9.2e-127 423.6 25.8 1.1e-126 423.4 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM44140.1 - 1.4e-19 70.3 37.7 4.6e-13 48.8 10.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.12 GAM44140.1 - 0.27 11.4 3.6 2.6 8.3 0.0 3.0 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 FAD_binding_4 PF01565.23 GAM44141.1 - 1.1e-16 60.8 3.3 1.1e-16 60.8 3.3 1.8 2 0 0 2 2 2 1 FAD binding domain Aft1_OSA PF11785.8 GAM44142.1 - 0.19 12.2 1.4 0.35 11.4 0.1 2.1 2 0 0 2 2 2 0 Aft1 osmotic stress response (OSM) domain Glyco_hydro_18 PF00704.28 GAM44143.1 - 5e-57 194.0 5.0 9e-57 193.2 5.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 GAM44143.1 - 1.9e-08 34.6 10.6 1.9e-08 34.6 10.6 4.2 4 1 0 4 4 4 1 Chitin recognition protein LysM PF01476.20 GAM44143.1 - 9.6e-05 22.4 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 LysM domain Aspzincin_M35 PF14521.6 GAM44144.1 - 2.6e-06 28.0 1.2 1.5e-05 25.5 0.6 2.4 1 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase Sec_GG PF07549.14 GAM44144.1 - 0.13 11.8 0.7 8 6.1 0.0 2.4 2 0 0 2 2 2 0 SecD/SecF GG Motif ATLF PF07737.11 GAM44145.1 - 0.11 11.8 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain Pectate_lyase_3 PF12708.7 GAM44146.1 - 2.9e-77 259.4 9.9 3.4e-75 252.6 7.9 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 GAM44146.1 - 0.045 13.5 1.3 0.08 12.7 0.2 2.0 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase GPHR_N PF12537.8 GAM44146.1 - 0.35 11.0 4.0 0.88 9.7 4.0 1.6 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal Peptidase_M91 PF14891.6 GAM44147.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 Effector protein Ank_4 PF13637.6 GAM44148.1 - 0.001 19.6 0.2 0.16 12.6 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM44148.1 - 0.0041 17.7 0.0 0.051 14.2 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAM44148.1 - 0.072 13.6 0.4 0.63 10.6 0.2 2.5 2 0 0 2 2 2 0 Ankyrin repeat Pkinase PF00069.25 GAM44149.1 - 2.2e-53 181.3 0.0 7.8e-45 153.3 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM44149.1 - 1.8e-28 99.5 0.0 5.5e-20 71.7 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAM44149.1 - 5e-07 29.3 0.1 7.9e-06 25.4 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 GAM44149.1 - 0.00054 19.4 0.1 0.0078 15.6 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family HXXSHH PF07586.11 GAM44149.1 - 0.0028 17.3 0.3 0.0053 16.4 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1552) GIT_CC PF16559.5 GAM44149.1 - 0.011 15.6 0.0 0.055 13.4 0.0 2.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fib_alpha PF08702.10 GAM44149.1 - 0.05 13.8 0.6 0.48 10.6 0.1 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Helo_like_N PF17111.5 GAM44150.1 - 1.3e-23 83.5 2.8 1.9e-23 83.0 2.8 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 GAM44150.1 - 1.1e-06 28.8 1.2 1.9e-06 28.1 0.1 1.9 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_2 PF12796.7 GAM44151.1 - 1.2e-73 243.7 2.6 8.5e-15 55.1 0.0 5.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM44151.1 - 9.2e-56 185.5 1.5 3e-12 46.8 0.1 6.2 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 GAM44151.1 - 4e-47 156.7 0.2 4.6e-06 26.8 0.1 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 GAM44151.1 - 1.3e-40 132.7 0.0 5.3e-06 26.4 0.0 7.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 GAM44151.1 - 5e-34 115.9 9.7 1e-09 38.5 0.1 5.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) NACHT PF05729.12 GAM44151.1 - 1.8e-09 37.7 0.0 3.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAM44151.1 - 0.00029 21.2 0.0 0.0011 19.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain EF1G PF00647.19 GAM44151.1 - 0.081 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Talaromyces_cellulolyticus-TcelY94_1.0/GCA_000829775.1_TcelY94_1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Talaromyces_cellulolyticus-TcelY94_1.0/GCA_000829775.1_TcelY94_1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Talaromyces_cellulolyticus-TcelY94_1.0/GCA_000829775.1_TcelY94_1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Talaromyces_cellulolyticus-TcelY94_1.0/GCA_000829775.1_TcelY94_1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 06:44:37 2019 # [ok]